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Sample records for european commission dg

  1. Impact assessment and policy learning in the European Commission

    SciTech Connect

    Ruddy, Thomas F. Hilty, Lorenz M.

    2008-02-15

    Governance for sustainable development requires policy coherence and Environmental Policy Integration, which are being hindered by difficulties coordinating the two separate impact assessment processes being conducted in the European Commission. One of them, the Commission-wide Impact Assessment process, looks primarily at EU-internal impacts, whereas the other one, Sustainability Impact Assessment (SIA) in DG Trade, looks outward to other countries and intergovernmental organizations. Ideally, the two processes should complement one another, especially as the two are set to continue being done in parallel. The paper uses a case study of the reform of the European sugar regime under a World Trade Organization ruling to demonstrate how the two impact assessment processes could better complement one another. Feedback from the experience had with existing trade agreements could then promote policy learning and inform the negotiations on new agreements. The number of new bilateral and Regional Trade Agreements is expected to continue rising, thus increasing the importance of the Commission-wide Impact Assessment process required for them.

  2. European Commission activities in eHealth.

    PubMed

    Olsson, Silas; Lymberis, Andreas; Whitehouse, Diane

    2004-12-01

    Health-care is an information-intensive and knowledge-demanding sector, which is why eHealth solutions are so important in this field. The European Commission (EC) has been initiating and funding research and development activities regarding Information and Communication Technologies (ICT) for health, or "eHealth", since 1988. These programmes covered priority topics like electronic health-care records, regional and national health networks, telemedicine in homecare and care-at-the-point-of-need to support continuity of care concepts, systems to support people to stay healthy, and systems and tools to support health professionals to work more efficiently and safely on patients. During the 15-year span of the programmes, the European Union (EU) has contributed about 500 million Euro to approximately 400 R&D projects, support activities, best practice and studies covering technical, clinical, ethical, legal, organisational and market issues. eHealth has shown proven benefits in application fields like improved access to care, care at the point-of-need, citizen-centred care, improved quality and cost containment. Such applications were on show at the EU High Level eHealth Conferences in Brussels, Belgium, in 2003, and in Cork, Ireland, in 2004. eHealth is now on the governmental agenda of EU Member States to be implemented on a broader scale. In line with this development, the Commission has taken a number of policy initiatives. A European Union Action Plan for a European eHealth Area was published by the Commission in April 2004 and endorsed by the EU health ministers in June 2004. This means that, for the first time, Europe has a coherent agenda for the implementation of eHealth. This report will concentrate on eHealth activities initiated by the Information Society Directorate-General of the European Commission.

  3. Meeting DG's

    ScienceCinema

    None

    2016-07-12

    Le DG J.Adams commente les 3 thèmes de la réunion: 1.) le prochain DG du Cern (qui sera H.Schopper) 2.) le LEP 3.) les conclusions du comité des finances concernant salaires, allocations etc. Discussion entre le DG J.Adams, Mons.Ullmann, chef du personel et l'auditoire

  4. A New Impetus for European Youth. European Commission White Paper.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium).

    Despite their highly divergent situations, young people largely share the same values, ambitions, and difficulties. Despite the more complex social and economic context in which young Europeans are currently living, they are well equipped to adapt. National and European policymakers must facilitate this process of change by making young people…

  5. Research on photonic components: the perspective of the European Commission

    NASA Astrophysics Data System (ADS)

    Kalbe, Gustav

    2008-11-01

    The importance of photonic technologies for the European economy is recognized by the European Union and enjoys continued support. The mechanisms of the European Union to support research and development by introducing the "7th European Framework Program for Collaborative Research" are outlined. The topical content of the Framework Program is presented, as well as its implementation and in particular the support of photonic components related research and development. We will highlight the importance of the collaborative European effort and give examples of its impact. We will then provide an overview of the current topics supported by the European Commission. We will conclude by presenting the long term vision and giving indications on the likely research priorities for Photonic Components in the ICT Workprogram 2009-2010 of the 7th Framework Program (FP7).

  6. The INQUA Loess Commission as a Central European Enterprise

    NASA Astrophysics Data System (ADS)

    Smalley, Ian; Markovic, Slobodan; O'Hara-Dhand, Ken

    2010-03-01

    The International Union of Quaternary Research (INQUA) organized the study and consideration of the Quaternary Period (the last 2.6 million years in Earth's history) via a set of commissions, sub-commissions, working groups, projects and programmes. One of the most successful and best records was the Loess Commission (LC) which functioned assub-commission and then commission from 1961 to 2003, resulting in 40 years of useful activity. The history of the LC can be divided into three phases: 1, from 1961-1977 when the President was Julius Fink; 2, from 1977-1991, with President Marton Pecsi; 3, from 1991-2003 with Presidents An Zhi-Sheng and Ian Smalley. Fink, from Vienna, and Pecsi, from Budapest, gave the LC a distinctly Central European aspect. The nature of loess in Central Europe influenced the nature of the LC but the settings for phases 1 and 2 were quite distinct. Phase 1 was a small scale academic operation, carried out in German. As phase 2 began in 1977 the scope expanded and Central Europe became a base for worldwide loess studies. where the LC language changed to English. Phase 2 was run from a National Geographical Institute and demonstrated a different approach to loess research, although the basic programmes of continent-wide mapping and stratigraphy remained the same. The Commission benefited from this change of style and emphasis. In phase 3 the administration moved away from Central Europe but the Finkian ethos remained solid.

  7. The European Commission proposal for a marine strategy: lacking substance.

    PubMed

    Salomon, Markus

    2006-11-01

    The European Commission's proposed Marine Strategy constitutes a highly inadequate approach to long-term protection of the European Seas. The main problem with the strategy is the restriction to a proposed directive in which only EU Member States are placed under obligation to develop their own environmental objectives and marine protection activity programmes. This 'renationalisation' results in the exclusion of key policy areas like Common Agricultural Policy (CAP) and Common Fishery Policy in which the EU has centralised powers. Furthermore, there is no plan to refine EU environmental law relevant to marine protection and nor are there any provisions for the linking of EU-level action with the international conventions for the protection of the oceans.

  8. European Union energy policy integration: A case of European Commission policy entrepreneurship and increasing supranationalism

    PubMed Central

    Maltby, Tomas

    2013-01-01

    Focusing on gas, this article explores the role of the European Commission in the process of European Union energy security policy development, and the extent to which the policy area is becoming increasingly supranational. Situating the article within the literature on agenda-setting and framing, it is argued that a policy window was opened as a result of: enlargement to include more energy import dependent states, a trend of increasing energy imports and prices, and gas supply disruptions. From the mid-2000s, the Commission contributed to a shift in political norms, successfully framing import dependency as a problem requiring an EU-level solution, based on the institution’s pre-existing preferences for a diversified energy supply and internal energy market. Whilst Member States retain significant sovereignty, the Commission has achieved since 2006 creeping competencies in the internal, and to a lesser extent external, dimensions of EU energy policy. PMID:24926115

  9. European Union energy policy integration: A case of European Commission policy entrepreneurship and increasing supranationalism.

    PubMed

    Maltby, Tomas

    2013-04-01

    Focusing on gas, this article explores the role of the European Commission in the process of European Union energy security policy development, and the extent to which the policy area is becoming increasingly supranational. Situating the article within the literature on agenda-setting and framing, it is argued that a policy window was opened as a result of: enlargement to include more energy import dependent states, a trend of increasing energy imports and prices, and gas supply disruptions. From the mid-2000s, the Commission contributed to a shift in political norms, successfully framing import dependency as a problem requiring an EU-level solution, based on the institution's pre-existing preferences for a diversified energy supply and internal energy market. Whilst Member States retain significant sovereignty, the Commission has achieved since 2006 creeping competencies in the internal, and to a lesser extent external, dimensions of EU energy policy.

  10. European Commission project: European Guideline for Target Group-Oriented Psychosocial Aftercare-Implementation.

    PubMed

    Vymetal, Stepan; Deistler, Albert; Bering, Robert; Schedlich, Claudia; Rooze, Magda; Orengo, Francisco; Zurek, Gisela; Krtickova, Michaela

    2011-06-01

    After disasters, the individual health and well-being of first responders and affected population are affected for years. Therefore, psychosocial help is needed. Although most victims recover on their own, a minority of survivors, members of rescue teams, or relatives develop long-term, disaster-related psychic disorders, such as post-traumatic stress disorder (PTSD). This subgroup especially should receive timely and appropriate psychosocial help. Many European countries offer post-disaster psychosocial care from a variety of caregivers (i.e., professionals and volunteers, non-governmental organizations, church or commercial organizations). Therefore, European standards for providing post-disaster psychosocial support currently is required. This article describes the project European Guideline for Target Group-Oriented Psychosocial Aftercare-Implementation, supported by the European Commission.

  11. Mobility as a Continuum: European Commission Mobility Policies for Schools and Higher Education

    ERIC Educational Resources Information Center

    Dvir, Yuval; Yemini, Miri

    2017-01-01

    This study explores the rationale and aims of European Commission (EC) mobility programmes for schools and higher education systems, namely the Comenius and the European Action Scheme for the Mobility of University Students (ERASMUS) funding schemes. Our findings indicate that the aims, rationales and means of mobility programmes for the school…

  12. [Environmental and occupational exposure to vitreous fibers: the initiatives of the European Commission].

    PubMed

    Aresini, G A

    1999-01-01

    The recent classification of a certain number of glass fibres by the European Commission within the framework of the Council Directive 67/548/CEE has reopened the debate on the carcinogenicity of these fibres at the level of the European Union. There is the risk of a law suit being field before the Court of Justice in Luxembourg against Germany, "guilty" of not having observed Community regulations. As regards worker protection, the recent Council Directive on chemical agents reviews the legal aspects concerning both preventive measures and the setting of limit values of occupational exposure.

  13. [The ethics review process in the Seventh Framework Programme of the European Commission].

    PubMed

    Pérez Blanco, V; Hirsch, F; González Pantaleón, P; Kritikos, M; Karatzas, I

    2010-01-01

    The Seventh Framework Programme of the European Commission (EC) is one of the most important instruments for public funding of research and technological development. Besides the scientific assessment of each proposal, the ethical issues raised in them are evaluated in accordance with the current European legislation and the ethical principles laid down in the international declarations supported by Member States. Such ethical review is organized by the "Governance and Ethics" Unit (Directorate-General for Research), although it is done by professionals from different sectors and backgrounds who register themselves voluntary in a database.

  14. Direct-to-consumer advertising of prescription drugs: European Commission persists in putting industry's interests first.

    PubMed

    2013-01-01

    In late September 2010, Members of the European Parliament (MEPs) issued their verdict on European Commission proposals aimed at lifting the ban on pharmaceutical companies communicating directly with the general public about prescription drugs. The MEPs were able to limit the scope of some of the more harmful aspects of these proposals, in particular by proposing that drug regulatory agencies should pre-screen the "information" produced by drug companies before it is made available to the public. In December 2010, faced with ongoing opposition from European Member States, the Commission appeared to back down, announcing that it was drawing up "amended proposals". They were publicly released in February 2012 but still leave the door open to direct-to-consumer advertising of prescription drugs, particularly "reminder advertising". As of 4 July 2012, the amended proposals had not yet been examined by Member States, thus obstructing the legislative process. Public health and management of the costs of social services for Member States are at stake. The Medicines in Europe Forum (MiEF) and the International Society of Drug Bulletins (ISDB) urge Member States to continue to refuse to examine the Commission's proposals, and have drawn up concrete counterproposals that would enable the general public to obtain relevant health information.

  15. Comparative decline in funding of European Commission malaria vaccine projects: what next for the European scientists working in this field?

    PubMed

    Thøgersen, Regitze L; Holder, Anthony A; Hill, Adrian V S; Arnot, David E; Imoukhuede, Egeruan B; Leroy, Odile

    2011-09-01

    Since 2000, under the Fifth and subsequent Framework Programmes, the European Commission has funded research to spur the development of a malaria vaccine. This funding has contributed to the promotion of an integrated infrastructure consisting of European basic, applied and clinical scientists in academia and small and medium enterprises, together with partners in Africa. Research has added basic understanding of what is required of a malaria vaccine, allowing selected candidates to be prioritized and some to be moved forward into clinical trials. To end the health burden of malaria, and its economic and social impact on development, the international community has now essentially committed itself to the eventual eradication of malaria. Given the current tentative advances towards elimination or eradication of malaria in many endemic areas, malaria vaccines constitute an additional and almost certainly essential component of any strategic plan to interrupt transmission of malaria. However, funding for malaria vaccines has been substantially reduced in the Seventh Framework Programme compared with earlier Framework Programmes, and without further support the gains made by earlier European investment will be lost.

  16. The History of Soil Mapping and Classification in Europe: The role of the European Commission

    NASA Astrophysics Data System (ADS)

    Montanarella, Luca

    2014-05-01

    Early systematic soil mapping in Europe dates back to the early times of soil science in the 19th Century and was developed at National scales mostly for taxation purposes. National soil classification systems emerged out of the various scientific communities active at that time in leading countries like Germany, Austria, France, Belgium, United Kingdom and many others. Different scientific communities were leading in the various countries, in some cases stemming from geological sciences, in others as a branch of agricultural sciences. Soil classification for the purpose of ranking soils for their capacity to be agriculturally productive emerged as the main priority, allowing in some countries for very detailed and accurate soil maps at 1:5,000 scale and larger. Detailed mapping was mainly driven by taxation purposes in the early times but evolved in several countries also as a planning and management tool for farms and local administrations. The need for pan-European soil mapping and classification efforts emerged only after World War II in the early 1950's under the auspices of FAO with the aim to compile a common European soil map as a contribution to the global soil mapping efforts of FAO at that time. These efforts evolved over the next decades, with the support of the European Commission, towards the establishment of a permanent network of National soil survey institutions (the European Soil Bureau Network). With the introduction of digital soil mapping technologies, the new European Soil Information System (EUSIS) was established, incorporating data at multiple scales for the EU member states and bordering countries. In more recent years, the formal establishment of the European Soil Data Centre (ESDAC) hosted by the European Commission, together with a formal legal framework for soil mapping and soil classification provided by the INSPIRE directive and the related standardization and harmonization efforts, has led to the operational development of advanced

  17. Status and commissioning results of the helium refrigerator plant for the European XFEL

    NASA Astrophysics Data System (ADS)

    Blum, L.; Wilhelm, H.; Petersen, B.; Schnautz, T.

    2015-12-01

    The European XFEL project is under construction at DESY in Germany. The superconducting XFEL linac is supplied by the XFEL helium refrigerator plant. This plant consists of two existing refrigerators, which were in service for the HERA storage ring until 2007. Since the XFEL linear accelerator requires cryogenic cooling at 2K, the existing cryogenic infrastructure had to be modified. Two of the three existing HERA helium refrigerators were required to cover the design heat load of the XFEL-linac. The refrigerator infrastructure was extended by a 2 K cooling loop, whose main component consists of a string of four cold compressors generating approximately 1.7 kW isothermal cooling capacity at 2K. The step by step commissioning and extension of the accelerator as well as the future upgrade option of the heat load demanded an extremely high turn down ability, a particular challenge for 2K cold compressor strings. The commissioning of the helium refrigerator infrastructure is underway and should be completed soon. The current status of this project, commissioning results and particular challenges are presented.

  18. Testing patients during seizures: A European consensus procedure developed by a joint taskforce of the ILAE - Commission on European Affairs and the European Epilepsy Monitoring Unit Association.

    PubMed

    Beniczky, Sándor; Neufeld, Miri; Diehl, Beate; Dobesberger, Judith; Trinka, Eugen; Mameniskiene, Ruta; Rheims, Sylvain; Gil-Nagel, Antonio; Craiu, Dana; Pressler, Ronit; Krysl, David; Lebedinsky, Angelina; Tassi, Laura; Rubboli, Guido; Ryvlin, Philippe

    2016-09-01

    There is currently no international consensus procedure for performing comprehensive periictal testing of patients in the epilepsy monitoring units (EMUs). Our primary goal was to develop a standardized procedure for managing and testing patients during and after seizures in EMUs. The secondary goal was to assess whether it could be implemented in clinical practice (feasibility). A taskforce was appointed by the International League Against Epilepsy (ILAE)-Commission on European Affairs and the European Epilepsy Monitoring Unit Association, to develop a standardized ictal testing battery (ITB) based on expert opinion and experience with various local testing protocols. ITB contains a comprehensive set of 10 items that evidence the clinically relevant semiologic features, and it is adaptive to the dynamics of the individual seizures. The feasibility of the ITB was prospectively evaluated on 250 seizures from 152 consecutive patients in 10 centers. ITB was successfully implemented in clinical practice in all 10 participating centers and was considered feasible in 93% of the tested seizures. ITB was not feasible for testing seizures of very short duration.

  19. 75 FR 54918 - Draft Regulatory Guide, DG-1247, “Design-Basis Hurricane and Hurricane Missiles for Nuclear Power...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... COMMISSION Draft Regulatory Guide, DG-1247, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power... issuance and availability of Draft Regulatory Guide (DG)--1247, ``Design-Basis Hurricane and Hurricane... permits and licenses. The draft regulatory guide (DG), entitled, ``Design-Basis Hurricane and...

  20. Environmental risk assessment of medicinal products for human use according to European Commission recommendations.

    PubMed

    Huschek, Gerd; Hansen, Peter D; Maurer, Hans H; Krengel, Dietmar; Kayser, Anja

    2004-06-01

    Presented here, based on new recommendations of the European Commission, is an environmental risk assessment (ERA) of a selected group of pharmaceuticals for Phase I, environmental exposure assessment, and Phase II Tier A, initial environmental fate and effect analysis. This pharmaceutical group is composed of the 111 highest-selling human drug substances that have annual sales in Germany of more than 5,000 kg. The data required for this ERA came from analyzing: (1) sales annually (in kg or IU) of the 2671 active pharmaceutical drug substances (2001) on the German market in all medicinal products sold by pharmacies (with and without prescriptions) and used in hospitals in 1996-2001; (2) the use pattern of drug substances as categorized according to Anatomical Therapeutic Chemical (ATC) classification indexes ATC3 and ATC7; (3) data for excretion, toxicity, and metabolites of the 111 selected human drug substances; (4) the physicochemical properties of these substances; and (5) the degradability of selected drug substances in sewage treatment plants (STPs) by using a validated and accredited liquid chromatography-electrospray ionization tandem mass spectrometry method. A correction factor for the pharmaceutical therapeutic (PT) activity of metabolites, the PT(Index) (excretion rate/100) for drug substances and PT active metabolites was established to refine the predicted environmental concentration (PEC(SURFACEWATER)). A refinement of the PEC(SURFACEWATER) was carried out with the market penetration factor of the human drug substances in Germany. In addition, for effect analysis the predicted no-effects concentration (PNEC) was calculated using assessment factors. The estimated PEC results were validated with the exposure results of effluents of the STPs. All results on ERA of drug substances have been documented in a Microsoft Access 2000 database.

  1. LCT for the European data relay system: in orbit commissioning of the Alphasat and Sentinel 1A LCTs

    NASA Astrophysics Data System (ADS)

    Heine, F.; Mühlnikel, G.; Zech, H.; Tröndle, D.; Seel, S.; Motzigemba, M.; Meyer, R.; Philipp-May, S.; Benzi, E.

    2015-03-01

    The European Data Relay System (EDRS) relies on optical communication links between Low Earth Orbit (LEO) and geostationary (GEO) spacecrafts. Data transmission at 1.8 Gbps between the S/Cs will be applied. EDRS is foreseen to go into operation in 2015. As a precursor to the EDRS GEO Laser Communication Terminals (LCT), an LCT is embarked on the Alphasat GEO S/C. Sentinel 1A is a LEO earth observation satellite as part of ESAs Copernicus program and carries an LCT on board. Both the Alphasat and the Sentinel 1A LCT have completed their individual in orbit commissioning and a joint link commissioning phase, with first LEO to GEO optical communication links in 2014. In this presentation, the design principle of the LCT applied for EDRS will be investigated. The most recent results of the in-orbit link commissioning phase of the LCTs on board of Alphasat and Sentinel 1A will be presented.

  2. The European Social Fund: The Commission, the Member State and Levels of Governance

    ERIC Educational Resources Information Center

    Brine, Jacqueline

    2004-01-01

    The European Social Fund (ESF) is the European Union structural fund that redistributes funds to facilitate vocational education and training (VET). With the exception of the Common Agricultural Policy it is the EU's largest instrument for redistribution. Currently linked to the European Employment Strategy it match-funds, and through its…

  3. Educational Innovations in Finnish and European Contexts: An Analysis of the Aims and Outcomes of "The European Observatory" of the European Commission (1994-1998). Research Report 200.

    ERIC Educational Resources Information Center

    Tella, Seppo; Tirri, Kirsi

    The purpose of this document is to analyze some of the major developments and research findings of the European Observatory of Innovations in Education and Training (1994-1998). The Observatory was a consortium of 13 member countries of the European Union serving as a European network of researchers and educators in the field of comparative…

  4. Electromagnetic fields: activities in the European Commission with a focus on research projects and the Scientific Committee of Emerging and Newly Identified Health Risks (SCENIHR).

    PubMed

    Meroni, Donata; Schreck, Stefan

    2015-09-01

    The article summarizes the main activities of the European Commission concerning electromagnetic fields. It explains also the regulatory context, with a special focus on past and current research projects funded by the European Union and the role of the SCENIHR in assessing risks related to EMF. Main conclusions of the SCENIHR opinion adopted in 2015 on EMF are reported.

  5. Astrobiology Road Mapping (AstRoMap) - A project within FP7 of the European Commission: First results

    NASA Astrophysics Data System (ADS)

    Gomez-Gomez, Felipe; Capria, Maria Teresa; Palomba, Ernesto; Walter, Nicolas; Rettberg, Petra; Muller, Christian; Horneck, Gerda

    AstRoMap (Astrobiology and Planetary Exploration Road Mapping) is a funded project formulated in the 5th Call of the European Commission FP7 framework. The main objectives of the AstRoMap are: 1. Identify the main astrobiology issues to be addressed by Europe in the next decades in relation with space exploration 2. Identify potential mission concepts that would allow addressing these issues 3. Identify the technology developments required to enable these missions 4. Provide a prioritized roadmap integrating science and technology activities as well as ground-based approach 5. Map scientific knowledge related to astrobiology in Europe To reach those objectives, AstRoMap is executed within the following steps: 1. Community consultation. In order to map the European astrobiology landscape and to provide a collaborative networking platform for this community, the AstRoMap project hosts a database of scientists (European and beyond) interested in astrobiology and planetary exploration (see: http://www.astromap.eu/database.html). It reflects the demography and the research and teaching activities of the astrobiology community, as well as their professional profiles and involvement in astrobiology projects. Considering future aspects of astrobiology in Europe, the need for more astrobiology-dedicated funding programmes at the EU level, especially for cross-disciplinary groups, was stressed. This might eventually lead to the creation of a European laboratory of Astrobiology, or even of a European Astrobiology Institute. 2. Workshops organisation. On the basis of the feedbacks from the community consultation, the potential participants and interesting topics are being identified to take part in the following workshops: 1-. Origin of organic compounds, steps to life; 2. Physico-chemical boundary conditions for habitability 3. Biosignatures as facilitating life detection 4. Origin of the Solar system 3. Astrobiology road-mapping. Based on the results and major conclusions

  6. [The EU law on genetically modified organisms: the European Commission changes the strategy in order to allow, restrict, or prohibit its culture].

    PubMed

    González Vaqué, Luis

    2010-01-01

    On July 13 2010, the European Commission adopted a series of measures which outline a new approach on Genetically Modified Organisms (GMOs) cultivation in the Member States. This proposal, which still retains the basis of the existing science-based GMO authorisation system, will be implemented through: a Communication from the Commission, explaining the new approach on the freedom for Member States to decide on the cultivation of genetically modified crops; the "Proposal for a Regulation of the European Parliament and of the Council amending Directive 2001/18/EC as regards the possibility for the Member States to restrict or prohibit the cultivation of GMOs in their territory"; and a new "European Commission Recommendation (2010/C 200/01) of 13 July 2010 on guidelines for the development of national co-existence measures to avoid the unintended presence of GMOs in conventional and organic crops".

  7. Assessing the Impacts of Revising the Tobacco Products Directive: Study to Support a DG SANCO Impact Assessment.

    PubMed

    Tiessen, Jan; Hunt, Priscillia; Celia, Claire; Fazekas, Mihaly; de Vries, Han; Staetsky, Laura; Diepeveen, Stephanie; Rabinovich, Lila; Ridsdale, Helen; Ling, Tom

    2011-01-01

    Tobacco use is one of the largest avoidable causes of morbidity and premature death in the EU. Whilst smoking prevalence in the EU has been declining over the past 30 years, smoking has remained more prevalent among men than women in the EU-27, with some of the new Member States reporting the widest gaps between male and female smokers. For young smokers (13 to 15 years old) this situation is somewhat reversed, with slightly more girls than boys smoking. Against this background, the European Commission Directorate-General for Health and Consumer Protection (DG SANCO) considered a revision of the Tobacco Products Directive 2001/37/EC across five general areas: scope of the directive, labelling requirements, registration and market control fees, ingredients, and sales arrangements. More specifically, the types of policy options under consideration included (but were not limited to): an increase of warning label sizes on the back of packaging to 100%, a restriction for the display of products at retail outlets and an introduction of additional measurement method for TNCO (the modified ISO method) with maximum limits set accordingly. DG SANCO commissioned RAND Europe to provide support in assessing the potential health, macroeconomic, and compliance cost and administrative burden impacts of revising the Tobacco Products Directive. In addition to assessing impacts, the study provides an up-to-date overview of the evidence and basis for current tobacco product regulation that may be of interest to a wider audience interested in tobacco control policies.

  8. Combining ISO/IEC 17025:2005 and European Commission Decision 2002/657 audit requirements: a practical way forward.

    PubMed

    Kay, Jack F

    2012-08-01

    Laboratories involved in the analyses of veterinary drug residues are under increasing pressure to demonstrate that they produce meaningful and reliable data. Quality assurance and quality control systems are implemented in laboratories to provide evidence of this and these are subject to external assessment to ensure that they are effective. Audits to ISO/IEC 17025:2005, an internationally accepted standard, and subsequent accreditation provide laboratories and their customers with a degree of assurance that the laboratories are operating in control and the data they report can be relied on. However, national or regional authorities may place additional requirements on laboratories to ensure quality data are reported. For example, in the European Union, all official control laboratories involved in veterinary drug residue analyses must also meet the requirements of European Commission Decision 2002/657/EC which sets performance criteria for analytical methods used in this area and these are subject to additional audits by national or regional authorities. All audits place considerable time and resource demands on laboratories and this paper discusses the burden audits place on laboratories and describes a UK initiative to combine these audits to the benefit of both the regulatory authority and the laboratory.

  9. Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission

    PubMed Central

    2011-01-01

    It was claimed by the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR)) in a report to the EU-Commission that "....no risks of adverse systemic effects exist and the current use of dental amalgam does not pose a risk of systemic disease..." [1, available from: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_016.pdf]. SCENIHR disregarded the toxicology of mercury and did not include most important scientific studies in their review. But the real scientific data show that: (a) Dental amalgam is by far the main source of human total mercury body burden. This is proven by autopsy studies which found 2-12 times more mercury in body tissues of individuals with dental amalgam. Autopsy studies are the most valuable and most important studies for examining the amalgam-caused mercury body burden. (b) These autopsy studies have shown consistently that many individuals with amalgam have toxic levels of mercury in their brains or kidneys. (c) There is no correlation between mercury levels in blood or urine, and the levels in body tissues or the severity of clinical symptoms. SCENIHR only relied on levels in urine or blood. (d) The half-life of mercury in the brain can last from several years to decades, thus mercury accumulates over time of amalgam exposure in body tissues to toxic levels. However, SCENIHR state that the half-life of mercury in the body is only "20-90 days". (e) Mercury vapor is about ten times more toxic than lead on human neurons and with synergistic toxicity to other metals. (f) Most studies cited by SCENIHR which conclude that amalgam fillings are safe have severe methodical flaws. PMID:21232090

  10. DEVELOPMENT OF HFE SECTIONS OF DG-1145.

    SciTech Connect

    HIGGINS,J.C.; OHARA, J.M.; BONGARRA, J.

    2007-03-26

    For the licensing of the current fleet of commercial nuclear power plants (NPPs), the Nuclear Regulatory Commission (NRC) used two key documents, NUREG-0800 and Regulatory Guide (RG) 1.70. RG 1.70 provided guidance to applicants on the contents needed in their Safety Analysis Reports (SARs) submitted as part of their application to construct or operate an NPP. NUREG-0800, the NRC Standard Review Plan (SRP), provides guidance to the NRR staff reviewers on performing their safety reviews of these applications. As part of the preparation for a new wave of improved NPP designs the NRC is in the process of updating the SRP and is also developing a new RG designated as draft RG or DG-1145, ''Combined License Applications for Nuclear Power Plants (LWR Edition).'' This will eventually become RG 1.206 and will take the place of RG 1.70. This will provide guidance for combined license (COL) applicants, as well as for other 10CFR Part 52 variations that are permitted.

  11. Development status of the X-ray beam diagnostics devices for the commissioning and user operation of the European XFEL

    NASA Astrophysics Data System (ADS)

    Grünert, Jan; Buck, Jens; Freund, Wolfgang; Ozkan, Cigdem; Molodtsov, Serguei

    2013-03-01

    X-ray Free-Electron-Lasers (XFEL) as the Linac Coherent Light Source (LCLS) in the USA, SACLA in Japan, and the European XFEL under construction in Germany are 4th generation light sources which allow research of at the same time extremely small structures (Ångström resolution) and extremely fast phenomena (femtosecond resolution). Unlike the pulses from a conventional optical laser, the radiation in these sources is created by the Self-Amplified Spontaneous Emission (SASE) process when electron bunches pass through very long segmented undulators. The shot noise at the origin of this process leads to significant pulse-to-pulse variations of pulse intensity, spectrum, wavefront, temporal properties etc. so that for user experiments an online monitoring of these properties is mandatory. Also, the adjustment of the long segmented undulators requires dedicated diagnostics such as an undulator commissioning spectrometer and spontaneous radiation analysis. The extremely high brilliance and resulting single-shot damage issue are difficult to handle for any XFEL diagnostics. Apart from the large energy range of operation of the facility from 280 eV to 25 keV in FEL fundamental, the particular challenge for the European XFEL diagnostics is the high intra bunch train photon pulse repetition rate of 4.5 MHz, potentially causing additional damage by high heat loads and making shot-to-shot diagnostics very demanding. This contribution reports on the facility concepts, recent progress in instrumentation development, and the optimization of diagnostics performance with respect to resolution/accuracy, shot-to-shot capabilities and energy range.

  12. Bayesian Inference for Time Trends in Parameter Values: Case Study for the Ageing PSA Network of the European Commission

    SciTech Connect

    Dana L. Kelly; Albert Malkhasyan

    2010-06-01

    There is a nearly ubiquitous assumption in PSA that parameter values are at least piecewise-constant in time. As a result, Bayesian inference tends to incorporate many years of plant operation, over which there have been significant changes in plant operational and maintenance practices, plant management, etc. These changes can cause significant changes in parameter values over time; however, failure to perform Bayesian inference in the proper time-dependent framework can mask these changes. Failure to question the assumption of constant parameter values, and failure to perform Bayesian inference in the proper time-dependent framework were noted as important issues in NUREG/CR-6813, performed for the U. S. Nuclear Regulatory Commission’s Advisory Committee on Reactor Safeguards in 2003. That report noted that “industry lacks tools to perform time-trend analysis with Bayesian updating.” This paper describes an application of time-dependent Bayesian inference methods developed for the European Commission Ageing PSA Network. These methods utilize open-source software, implementing Markov chain Monte Carlo sampling. The paper also illustrates the development of a generic prior distribution, which incorporates multiple sources of generic data via weighting factors that address differences in key influences, such as vendor, component boundaries, conditions of the operating environment, etc.

  13. Patients' understanding of risk associated with medication use: impact of European Commission guidelines and other risk scales.

    PubMed

    Berry, Dianne C; Raynor, D K; Knapp, Peter; Bersellini, Elisabetta

    2003-01-01

    Patients want and need comprehensive and accurate information about their medicines so that they can participate in decisions about their healthcare. In particular, they require information about the likely risks and benefits that are associated with the different treatment options. However, to provide this information in a form that people can readily understand and use is a considerable challenge to healthcare professionals. One recent attempt to standardise the language of risk has been to produce sets of verbal descriptors that correspond to specific probability ranges, such as those outlined in the European Commission (EC) Pharmaceutical Committee guidelines in 1998 for describing the incidence of adverse effects. This paper provides an overview of a number of studies involving members of the general public, patients, and hospital doctors, that evaluated the utility of the EC guideline descriptors (very common, common, uncommon, rare, very rare). In all studies it was found that people significantly over-estimated the likelihood of adverse effects occurring, given specific verbal descriptors. This in turn resulted in significantly higher ratings of their perceived risks to health and significantly lower ratings of their likelihood of taking the medicine. Such problems of interpretation are not restricted to the EC guideline descriptors. Similar levels of misinterpretation have also been demonstrated with two other recently advocated risk scales (Calman's verbal descriptor scale and Barclay, Costigan and Davies' lottery scale). In conclusion, the challenge for risk communicators and for future research will be to produce a language of risk that is sufficiently flexible to take into account different perspectives, as well as changing circumstances and contexts of illness and its treatments. In the meantime, we urge the EC and other legislative bodies to stop recommending the use of specific verbal labels or phrases until there is a stronger evidence base to

  14. Public funding for research on antibacterial resistance in the JPIAMR countries, the European Commission, and related European Union agencies: a systematic observational analysis

    PubMed Central

    Kelly, Ruth; Zoubiane, Ghada; Walsh, Desmond; Ward, Rebecca; Goossens, Herman

    2016-01-01

    priority topics we found that 763 (63%) of 1208 projects funded at national level were within the area of therapeutics, versus 185 (15%) in transmission, 131 (11%) in diagnostics, 53 (4%) in interventions, and only 37 (3%) in environment and 39 (3%) in surveillance. Interpretation This was the first systematic analysis of research funding of antibacterial resistance of this scale and scope, which relied on the availability and accuracy of data from organisations included. Large variation was seen between countries both in terms of number of projects and associated investment and across the six priority topics. To determine the future direction of JPIAMR countries a clear picture of the funding landscape across Europe and Canada is needed. Countries should work together to increase the effect of research funding by strengthening national and international coordination and collaborations, harmonising research activities, and collectively pooling resources to fund multidisciplinary projects. The JPIAMR have developed a publicly available database to document the antibacterial resistance research collected and can be used as a baseline to analyse funding from 2014 onwards. Funding JPIAMR and the European Commission. PMID:26708524

  15. The prospects for using (Q)SARs in a changing political environment--high expectations and a key role for the European Commission's joint research centre.

    PubMed

    Worth, A P; Van Leeuwen, C J; Hartung, T

    2004-01-01

    Recent policy developments in the European union (EU) and within the Organisation for Economic Cooperation and Development (OECD) have placed increased emphasis on the use of structure-activity relationships (SARs) and quantitative structure-activity relationships (QSARs), collectively referred to as (Q)SARs, within various regulatory programmes for the assessment of chemicals and products. The most significant example within the EU is the European commission's proposal (of 29 October 2003) to introduce a new system for managing chemicals (called REACH), which calls for an increased use of (Q)SARs and other non-animal methods, especially for the assessment of low production volume chemicals. Another development within the EU is the Seventh Amendment to the Cosmetics Directive, which foresees the phasing out of animal testing on cosmetics, combined with the imposition of marketing bans on cosmetics that have been tested on animals after certain deadlines. At the same time, the Existing Chemicals programme within the OECD is investigating ways of increasing the use of chemical category approaches, which depend heavily on the use of (Q)SARs, activity-activity relationships and read-across. Such developments are placing an enormous challenge on industry, regulatory bodies, and on the European commission's Joint Research Centre (JRC), which is responsible for providing independent scientific advice to policy makers in the European Commission and the Member States. This paper reviews the different scientific and regulatory purposes for which reliable (Q)SARs could be used, and describes the current work of the JRC in providing scientific support for the development, validation and implementation of (Q)SARs.

  16. The Commission of the European Communities and the Evolution of Common Policies: A Bibliographical Survey (1958-1974)

    ERIC Educational Resources Information Center

    Hopkins, M.

    1976-01-01

    Highlights those often fugitive documents that stand out as important landmarks in the evolution of common policies above the mass of technical and ephemeral documentation generated by the Commission. (Author)

  17. NoiseChem: an European Commission research project on the effects of exposure to noise and industrial chemicals on hearing and balance.

    PubMed

    Prasher, Deepak; Morata, Thais; Campo, Pierre; Fechter, Lawrence; Johnson, Ann-Christin; Lund, Soren Peter; Pawlas, Krystyna; Starck, Jukka; Sułkowski, Wiesław; Sliwinska-Kowalska, Mariola

    2002-01-01

    Exposure to multiple physical and chemical agents is common in occupational environments but workplace hazards and occupational safety criteria for combined exposures are lacking. NoiseChem is an European Commission research project examining the effects of exposure to noise and chemicals on hearing and balance. Partners in Sweden, Finland, France, Denmark, UK and Poland with expert guidance from partners in the USA will examine workers and study the mechanisms of action in animals to determine the levels of risk associated with joint exposure to noise and solvents. This paper briefly outlines the project details.

  18. Investigating the Discourse on Social Cohesion in Relation to Innovation through the Vocabulary of European Commission Communications

    ERIC Educational Resources Information Center

    Villalba, Ernesto

    2008-01-01

    After the relaunch of the Lisbon Strategy, innovation has become one of the main areas of interest in the European Union (EU). In general terms, innovation is always seen as a driver of economic growth and a necessary element to achieve the strategic goal set by the EU in 2000 of becoming the most competitive knowledge-based economy. The strategic…

  19. Combined effect of CVR and penetration of DG in the voltage profile and losses of lowvoltage secondary distribution networks

    NASA Astrophysics Data System (ADS)

    Bokhari, Abdullah

    Demarcations between traditional distribution power systems and distributed generation (DG) architectures are increasingly evolving as higher DG penetration is introduced in the system. The concerns in existing electric power systems (EPSs) to accommodate less restrictive interconnection policies while maintaining reliability and performance of power delivery have been the major challenge for DG growth. In this dissertation, the work is aimed to study power quality, energy saving and losses in a low voltage distributed network under various DG penetration cases. Simulation platform suite that includes electric power system, distributed generation and ZIP load models is implemented to determine the impact of DGs on power system steady state performance and the voltage profile of the customers/loads in the network under the voltage reduction events. The investigation designed to test the DG impact on power system starting with one type of DG, then moves on multiple DG types distributed in a random case and realistic/balanced case. The functionality of the proposed DG interconnection is designed to meet the basic requirements imposed by the various interconnection standards, most notably IEEE 1547, public service commission, and local utility regulation. It is found that implementation of DGs on the low voltage secondary network would improve customer's voltage profile, system losses and significantly provide energy savings and economics for utilities. In a network populated with DGs, utility would have a uniform voltage profile at the customers end as the voltage profile becomes more concentrated around targeted voltage level. The study further reinforced the concept that the behavior of DG in distributed network would improve voltage regulation as certain percentage reduction on utility side would ensure uniform percentage reduction seen by all customers and reduce number of voltage violations.

  20. The fast-spectrum transmutation experimental facility FASTEF: Main design achievements (Part 1: Core and primary system) within the FP7-CDT collaborative project of the European Commission

    SciTech Connect

    De Bruyn, D.; Fernandez, R.; Mansani, L.; Woaye-Hune, A.; Sarotto, M.; Bubelis, E.

    2012-07-01

    MYRRHA (Multi-purpose hybrid Research Reactor for High-tech Applications) is the flexible experimental accelerator-driven system (ADS) in development at SCK CEN in replacement of its material testing reactor BR2. SCK CEN in association with 17 European partners from industry, research centres and academia, responded to the FP7 (Seventh Framework Programme) call from the European Commission to establish a Central Design Team (CDT) for the design of a Fast Spectrum Transmutation Experimental Facility (FASTEF) able to demonstrate efficient transmutation and associated technology through a system working in subcritical and/or critical mode. The project has started on April 01, 2009 for a period of three years. In this paper, we present the latest configuration of the reactor core and primary system. The FASTEF facility has evolved quite a lot since the intermediate reporting done at the ICAPP'10 and ICAPP'11 conferences 1 2. If it remains a small-scale facility, the core power amounts now up to 100 MWth in critical mode. In a companion paper 3, we present the concept of the reactor building and the plant layout. (authors)

  1. e-Infrastructures for e-Sciences 2013 A CHAIN-REDS Workshop organised under the aegis of the European Commission

    NASA Astrophysics Data System (ADS)

    The CHAIN-REDS Project is organising a workshop on "e-Infrastructures for e-Sciences" focusing on Cloud Computing and Data Repositories under the aegis of the European Commission and in co-location with the International Conference on e-Science 2013 (IEEE2013) that will be held in Beijing, P.R. of China on October 17-22, 2013. The core objective of the CHAIN-REDS project is to promote, coordinate and support the effort of a critical mass of non-European e-Infrastructures for Research and Education to collaborate with Europe addressing interoperability and interoperation of Grids and other Distributed Computing Infrastructures (DCI). From this perspective, CHAIN-REDS will optimise the interoperation of European infrastructures with those present in 6 other regions of the world, both from a development and use point of view, and catering to different communities. Overall, CHAIN-REDS will provide input for future strategies and decision-making regarding collaboration with other regions on e-Infrastructure deployment and availability of related data; it will raise the visibility of e-Infrastructures towards intercontinental audiences, covering most of the world and will provide support to establish globally connected and interoperable infrastructures, in particular between the EU and the developing regions. Organised by IHEP, INFN and Sigma Orionis with the support of all project partners, this workshop will aim at: - Presenting the state of the art of Cloud computing in Europe and in China and discussing the opportunities offered by having interoperable and federated e-Infrastructures; - Exploring the existing initiatives of Data Infrastructures in Europe and China, and highlighting the Data Repositories of interest for the Virtual Research Communities in several domains such as Health, Agriculture, Climate, etc.

  2. Waste Isolation Pilot Plant Materials Interface Interactions Test: Papers presented at the Commission of European Communities workshop on in situ testing of radioactive waste forms and engineered barriers

    SciTech Connect

    Molecke, M.A.; Sorensen, N.R.; Wicks, G.G.

    1993-08-01

    The three papers in this report were presented at the second international workshop to feature the Waste Isolation Pilot Plant (WIPP) Materials Interface Interactions Test (MIIT). This Workshop on In Situ Tests on Radioactive Waste Forms and Engineered Barriers was held in Corsendonk, Belgium, on October 13--16, 1992, and was sponsored by the Commission of the European Communities (CEC). The Studiecentrum voor Kernenergie/Centre D`Energie Nucleaire (SCK/CEN, Belgium), and the US Department of Energy (via Savannah River) also cosponsored this workshop. Workshop participants from Belgium, France, Germany, Sweden, and the United States gathered to discuss the status, results and overviews of the MIIT program. Nine of the twenty-five total workshop papers were presented on the status and results from the WIPP MIIT program after the five-year in situ conclusion of the program. The total number of published MIIT papers is now up to almost forty. Posttest laboratory analyses are still in progress at multiple participating laboratories. The first MIIT paper in this document, by Wicks and Molecke, provides an overview of the entire test program and focuses on the waste form samples. The second paper, by Molecke and Wicks, concentrates on technical details and repository relevant observations on the in situ conduct, sampling, and termination operations of the MIIT. The third paper, by Sorensen and Molecke, presents and summarizes the available laboratory, posttest corrosion data and results for all of the candidate waste container or overpack metal specimens included in the MIIT program.

  3. Declaration of the European Ministers of Vocational Education and Training, and the European Commission, Convened in Copenhagen on 29 and 30 November 2002, on Enhanced European Cooperation in Vocational Education and Training. "The Copenhagen Declaration."

    ERIC Educational Resources Information Center

    European Commission, Brussels (Belgium).

    Enhanced cooperation in vocational education and training (VET) will be an important contribution toward ensuring a successful enlargement of the European Union. The social partners play an indispensable role in development, validation, and recognition of vocational competencies and qualifications at all levels and are partners in promotion of…

  4. The Degradation of dG Phosphoramidites in Solution.

    PubMed

    Hargreaves, John S; Kaiser, Robert; Wolber, Paul K

    2015-01-01

    The reaction of 2'-deoxynucleoside phosphoramidites with water is an important degradation reaction that limits the lifetimes of reagents used for chemical deoxyoligonucleotide synthesis. The hydrolysis of nucleoside phosphoramidites in solution has therefore been investigated. The degree of degradation depends not only on the presence of water but also on the specific nucleoside, 2'-deoxyguanosine (dG) being especially susceptible. Additionally, the nature of the group protecting the exocyclic amine on the nucleoside base strongly influences the rate of hydrolysis. For dG, the degradation is second order in phosphoramidite concentration, indicating autocatalysis of the hydrolysis reaction. Comparison of the degradation rates of dG phosphoramidites with different protecting groups as well as with phosphoramidites containing bases that are structurally similar to dG affords clues to the nature of how dG catalyzes its own destruction and indicates a direct correlation between ease of protecting group removal and propensity to undergo autocatalytic degradation.

  5. "FACILS 2014: Microbially-driven facilitation systems in environmental biotechnology" (hereafter "FACILS") presented here by the European Commission (EC)-United States (US) Task Force on Biotechnology Research

    SciTech Connect

    Methe, Barbara

    2016-02-03

    As we enter the 21st century, the sustainability of the biosphere is a global challenge that can best be met with a global response. This includes how we train and promote our next generation of research scientists in the emerging arenas of genome-enabled biology and a bio-based economy. It is this fundamental issue that formed the motivation for designing and conducting a shortcourse entitled “FACILIS 2014: Microbially-driven facilitation systems in environmental biotechnology” (hereafter “FACILIS”) presented here by the European Commission (EC)-United States (US) Task Force on Biotechnology Research. This WG was established in 1994 under the umbrella of the US-EC Task Force on Biotechnology Research, a transatlantic collaborative group overseen by the US Office of Science and Technology Policy (OSTP) and the EC. The Environmental Biotechnology Working Group maintains several goals, including establishing research links between scientists in EU countries and the US and fostering the careers of junior scientists from both sides of the Atlantic to the global nature of scientific cooperation. To that end, a shortcourse was held at the University of Milan in Italy on July 12-25 2014 organized around cross-cutting themes of genomic science and designed to attract a stellar group of interdisciplinary early carrier researchers. A total of 22 students, 10 from the US and 12 from the EU participated. The course provided them with hands-on experience with the latest scientific methods in genomics and bioinformatics; using a format that combines lectures, laboratory research and field work with the final goal to enable researchers to finally turn data into knowledge.

  6. CASAM: a European R&T project for the protection of commercial aircrafts in flight

    NASA Astrophysics Data System (ADS)

    Tholl, Hans Dieter; Vergnolle, Jean-Francois

    2008-10-01

    CASAM (Civil Aircraft Security Against Manpads) is a Framework Program 6 (FP 6) Project launched by the European Commission, DG Research-Aeronautics, binding together a group of 18 companies and research institutions from majors to SMEs. The global objective of the CASAM Project is to design, build, test and validate on ground a closed-loop laser-based DIRCM (Directed IR Countermeasure) equipment for jamming an infrared guided missile fired against a commercial airliner. The broad expertise of the CASAM team allows to address all technical, financial and legal matters dealing with the challenging topic of protecting civilian aircrafts against MANPADS. This paper reviews the main aspects of the projects.

  7. ATF2 Commissioning

    SciTech Connect

    Seryi, A.; Christian, G.; Parker, B.; Schulte, D.; Delahaye, J.-P.; Tomas, R.; Zimmermann, F.; Wolski, A.; Elsen, E.; Sanuki, T.; Gianfelice-Wendt, E.; Ross, M.; Wendt, M.; Takahashi, T.; Bai, S.; Gao, J.; Bolzon, B.; Geffroy, N.; Jeremie, A.; Apsimon, R.; Burrows, P.; /Oxford U., JAI /Kyoto U., Inst. Chem. Res. /Kyungpook Natl. U. /Orsay, LAL /Phang Accelerator Lab /Royal Holloway, U. of London /SLAC /Daresbury /University Coll. London /Manchester U. /Univ. of Tokyo U.

    2009-10-30

    ATF2 is a final-focus test beam line that aims to focus the low-emittance beam from the ATF damping ring to a beam size of about 37 nm, and at the same time to demonstrate nm beam stability, using numerous advanced beam diagnostics and feedback tools. The construction has been finished at the end of 2008 and the beam commissioning of ATF2 has started in December of 2008. ATF2 is constructed and commissioned by ATF international collaborations with strong US, Asian and European participation.

  8. Classification of skin sensitizing substances: a comparison between approaches used by the DFG-MAK Commission and the European Union legislation.

    PubMed

    Lessmann, H; Uter, W; Diepgen, T L; Drexler, H; Fartasch, M; Greim, H; Hartwig, A; Kreis, P; Löser, E; Merget, R; Merk, H; Nowak, D; Rothe, A; Stropp, G; Schnuch, A

    2011-10-01

    A systematic classification of substances (or mixtures of substances) with regard to various toxicological endpoints is a prerequisite for the implementation of occupational safety strategies. As its principal task the "Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area" of the "Deutsche Forschungsgemeinschaft" (DFG-MAK Commission) derives and recommends maximum workplace concentrations and biological tolerance values (MAK and BAT values) based exclusively on scientific arguments. Several endpoints are evaluated separately in detail, e.g. carcinogenicity, risks during pregnancy, germ cell mutagenicity or contribution to systemic toxicity after cutaneous absorption. Skin- and airway sensitization is also considered; the present paper focuses on these two endpoints.

  9. Commissioning MMS

    NASA Technical Reports Server (NTRS)

    Wood, Paul; Gramling, Cheryl; Stone, John; Smith, Patrick; Reiter, Jenifer

    2016-01-01

    This paper discusses commissioning of NASAs Magnetospheric MultiScale (MMS) Mission. The mission includes four identical spacecraft with a large, complex set of instrumentation. The planning for and execution of commissioning for this mission is described. The paper concludes by discussing lessons learned.

  10. The Impact on Education for Librarianship and Information Studies of the Bologna Process and Related European Commission Programmes--and Some Outstanding Issues in Europe and Beyond

    ERIC Educational Resources Information Center

    Johnson, Ian M.

    2013-01-01

    The Bologna Declaration of 1999 is the basis for continuing reforms in higher education intended to support international mobility in employment within the European Union. This paper describes the standardised structure and nomenclature for courses that have been implemented, together with a credit transfer system, a quality assurance regime, and…

  11. Joint Commission

    MedlinePlus

    Skip to main content The Joint Commission Log In | Request Guest Access Forgot password? | Log In Help Contact Us | Careers | JCR Web Store | Press Room Search Home Accreditation Accreditation Ambulatory Health ...

  12. Maternal obesity in Europe: where do we stand and how to move forward?: A scientific paper commissioned by the European Board and College of Obstetrics and Gynaecology (EBCOG).

    PubMed

    Devlieger, Roland; Benhalima, Katrien; Damm, Peter; Van Assche, André; Mathieu, Chantal; Mahmood, Tahir; Dunne, Fidelma; Bogaerts, Annick

    2016-06-01

    Paralleling the global epidemic of obesity figures in the general population, the incidence of maternal obesity (BMI>30kg/m(2) at the start of pregnancy) has been rising over the last world. While most European countries do not systematically report obesity figures in their pregnant population, the prevalence of maternal obesity varies from 7 to 25% and seems strongly related to social and educational inequalities. Obesity during pregnancy represents an important preventable risk factor for adverse pregnancy outcomes and is associated with negative long-term health outcomes for both mothers and offspring. These effects are often aggravated by the high incidence of abnormal glucose tolerance and excessive gestational weight gain found in this group. The main controversies around the management of the obese pregnant women are related to (1) the value of repeated weighing during pregnancy, (2) the optimal gestational weight gain to advise and the lifestyle messages to deliver in order to achieve this, (3) the optimal strategy and timing of screening for gestational diabetes (GDM) and (4) the optimal timing and mode of delivery. These controversies are reviewed in this review, with the exception of screening for gestational diabetes that is discussed extensively elsewhere in this issue (Benhalima et al.). An agenda for research is proposed with the hope that it will catch the attention of policy-makers and funders and ultimately lead to the development of European-wide evidence-based guidelines for clinicians.

  13. Meeting the European Commission performance criteria for the use of triple quadrupole GC-MS/MS as a confirmatory method for PCDD/Fs and dl-PCBs in food and feed samples.

    PubMed

    Ábalos, Manuela; Cojocariu, Cristian I; Silcock, Paul; Roberts, Dominic; Pemberthy, Diana M; Sauló, Jordi; Abad, Esteban

    2016-05-01

    Until recently, European Union (EU) legislation required the use of high-resolution gas chromatography coupled to high-resolution mass spectrometry (HRGC-HRMS) based on magnetic sector analyzers as a standard approach for confirmatory analysis of dioxins (PCDDs) and furans (PCDFs) in feed and food. However, recent technological advances in MS instruments enabled other alternative analytical techniques to meet the same analytical criteria as those requested for HRGC-HRMS. In this sense, triple quadrupoles (GC-MS/MS) can be a realistic alternative for the analysis of dioxins. In this work, the performance of GC-MS/MS technology was evaluated against the criteria demanded by the EU for confirmatory analysis of dioxins and PCBs in food and feed. Thus, the study comprises a number of parameters including chromatographic separation, limit of quantification, linearity, repeatability, and ion ratio precision. Analyses of solvent standards as well as sample extracts (inter-calibration extracts and certified reference materials) were also considered within the scope of this study. Additionally, direct comparisons of the results obtained by GC-MS/MS with those from GC-HRMS were made. The results of this work suggested that GC-MS/MS was highly sensitive and selective for confirmatory analysis of PCDD/Fs and related compounds in food and feed samples and meets all the criteria requested by the European Commission.

  14. WATER VAPOR IN THE PROTOPLANETARY DISK OF DG Tau

    SciTech Connect

    Podio, L.; Dougados, C.; Thi, W.-F.; Menard, F.; Pinte, C.; Codella, C.; Cabrit, S.; Nisini, B.; Sandell, G.; Williams, J. P.; Testi, L.; Woitke, P.

    2013-03-20

    Water is key in the evolution of protoplanetary disks and the formation of comets and icy/water planets. While high-excitation water lines originating in the hot inner disk have been detected in several T Tauri stars (TTSs), water vapor from the outer disk, where most water ice reservoirs are stored, was only reported in the nearby TTS TW Hya. We present spectrally resolved Herschel/HIFI observations of the young TTS DG Tau in the ortho- and para-water ground-state transitions at 557 and 1113 GHz. The lines show a narrow double-peaked profile, consistent with an origin in the outer disk, and are {approx}19-26 times brighter than in TW Hya. In contrast, CO and [C II] lines are dominated by emission from the envelope/outflow, which makes H{sub 2}O lines a unique tracer of the disk of DG Tau. Disk modeling with the thermo-chemical code ProDiMo indicates that the strong UV field, due to the young age and strong accretion of DG Tau, irradiates a disk upper layer at 10-90 AU from the star, heating it up to temperatures of 600 K and producing the observed bright water lines. The models suggest a disk mass of 0.015-0.1 M{sub Sun }, consistent with the estimated minimum mass of the solar nebula before planet formation, and a water reservoir of {approx}10{sup 2}-10{sup 3} Earth oceans in vapor and {approx}100 times larger in the form of ice. Hence, this detection supports the scenario of ocean delivery on terrestrial planets by the impact of icy bodies forming in the outer disk.

  15. Dynamic Rupture Benchmarking of the ADER-DG Method

    NASA Astrophysics Data System (ADS)

    Pelties, C.; Gabriel, A.

    2012-12-01

    We will verify the arbitrary high-order derivative Discontinuous Galerkin (ADER-DG) method in various test cases of the 'SCEC/USGS Dynamic Earthquake Rupture Code Verification Exercise' benchmark suite (Harris et al. 2009). The ADER-DG scheme is able to solve the spontaneous rupture problem with high-order accuracy in space and time on three-dimensional unstructured tetrahedral meshes. Strong mesh coarsening or refinement at areas of interest can be applied to keep the computational costs feasible. Moreover, the method does not generate spurious high-frequency contributions in the slip rate spectra and therefore does not require any artificial damping as demonstrated in previous presentations and publications (Pelties et al. 2010 and 2012). We will show that the mentioned features hold also for more advanced setups as e.g. a branching fault system, heterogeneous background stresses and bimaterial faults. The advanced geometrical flexibility combined with an enhanced accuracy will make the ADER-DG method a useful tool to study earthquake dynamics on complex fault systems in realistic rheologies. References: Harris, R.A., M. Barall, R. Archuleta, B. Aagaard, J.-P. Ampuero, H. Bhat, V. Cruz-Atienza, L. Dalguer, P. Dawson, S. Day, B. Duan, E. Dunham, G. Ely, Y. Kaneko, Y. Kase, N. Lapusta, Y. Liu, S. Ma, D. Oglesby, K. Olsen, A. Pitarka, S. Song, and E. Templeton, The SCEC/USGS Dynamic Earthquake Rupture Code Verification Exercise, Seismological Research Letters, vol. 80, no. 1, pages 119-126, 2009 Pelties, C., J. de la Puente, and M. Kaeser, Dynamic Rupture Modeling in Three Dimensions on Unstructured Meshes Using a Discontinuous Galerkin Method, AGU 2010 Fall Meeting, abstract #S21C-2068 Pelties, C., J. de la Puente, J.-P. Ampuero, G. Brietzke, and M. Kaeser, Three-Dimensional Dynamic Rupture Simulation with a High-order Discontinuous Galerkin Method on Unstructured Tetrahedral Meshes, JGR. - Solid Earth, VOL. 117, B02309, 2012

  16. Dynamic Rupture Benchmarking of the ADER-DG Method

    NASA Astrophysics Data System (ADS)

    Gabriel, Alice; Pelties, Christian

    2013-04-01

    We will verify the arbitrary high-order derivative Discontinuous Galerkin (ADER-DG) method in various test cases of the 'SCEC/USGS Dynamic Earthquake Rupture Code Verification Exercise' benchmark suite (Harris et al. 2009). The ADER-DG scheme is able to solve the spontaneous rupture problem with high-order accuracy in space and time on three-dimensional unstructured tetrahedral meshes. Strong mesh coarsening or refinement at areas of interest can be applied to keep the computational costs feasible. Moreover, the method does not generate spurious high-frequency contributions in the slip rate spectra and therefore does not require any artificial damping as demonstrated in previous presentations and publications (Pelties et al. 2010 and 2012). We will show that the mentioned features hold also for more advanced setups as e.g. a branching fault system, heterogeneous background stresses and bimaterial faults. The advanced geometrical flexibility combined with an enhanced accuracy will make the ADER-DG method a useful tool to study earthquake dynamics on complex fault systems in realistic rheologies. References: Harris, R.A., M. Barall, R. Archuleta, B. Aagaard, J.-P. Ampuero, H. Bhat, V. Cruz-Atienza, L. Dalguer, P. Dawson, S. Day, B. Duan, E. Dunham, G. Ely, Y. Kaneko, Y. Kase, N. Lapusta, Y. Liu, S. Ma, D. Oglesby, K. Olsen, A. Pitarka, S. Song, and E. Templeton, The SCEC/USGS Dynamic Earthquake Rupture Code Verification Exercise, Seismological Research Letters, vol. 80, no. 1, pages 119-126, 2009 Pelties, C., J. de la Puente, and M. Kaeser, Dynamic Rupture Modeling in Three Dimensions on Unstructured Meshes Using a Discontinuous Galerkin Method, AGU 2010 Fall Meeting, abstract #S21C-2068 Pelties, C., J. de la Puente, J.-P. Ampuero, G. Brietzke, and M. Kaeser, Three-Dimensional Dynamic Rupture Simulation with a High-order Discontinuous Galerkin Method on Unstructured Tetrahedral Meshes, JGR. - Solid Earth, VOL. 117, B02309, 2012

  17. DG Planning with Amalgamation of Operational and Reliability Considerations

    NASA Astrophysics Data System (ADS)

    Battu, Neelakanteshwar Rao; Abhyankar, A. R.; Senroy, Nilanjan

    2016-04-01

    Distributed Generation has been playing a vital role in dealing issues related to distribution systems. This paper presents an approach which provides policy maker with a set of solutions for DG placement to optimize reliability and real power loss of the system. Optimal location of a Distributed Generator is evaluated based on performance indices derived for reliability index and real power loss. The proposed approach is applied on a 15-bus radial distribution system and a 18-bus radial distribution system with conventional and wind distributed generators individually.

  18. The evaluation of technical models used for major-accident hazard installations. Report to Commission of the European Communities Directorate General 12

    NASA Astrophysics Data System (ADS)

    Britter, R. E.

    1991-08-01

    Models are used in many ways by individuals and organizations within the European Community. Within the context of major technological hazards decisions of considerable importance are based wholly, or partly, on these models. The quality, that is the fitness-for-purpose, of these models will differ and there is obviously an interest in both the relative quality of one model against another and the absolute quality of any particular model. This leads to the evaluation of model quality and to methods by which model quality might be improved. It is noted that models are a principal method for the transfer of technology but also that the nature, role, and limitations of models is frequently misunderstood. There is a widespread demand for guidance on model quality and consequently on the development of evaluation techniques. The CEC is an appropriate body to have a role in the study of the quality and the management of quality of technical models. The evaluation of the quality of technical models entails: (1) an assurance of correct coding of algorithms is required and this is probably straightforward; (2) a statistical model validation is required and this entails comparison with experimental data sets (considerable care is required in performing such a validation, in particular in determination of an appropriate protocol to ensure unambiguous conclusions to be drawn from the validation); and (3) a model assessment including a scientific review and other less objective aspects is also required and should be given equal weight to a statistical model validation. Actions which may lead to an improvement in model quality are presented.

  19. Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis.

    PubMed

    Shimaji, Kouhei; Konishi, Takahiro; Tanaka, Shintaro; Yoshida, Hideki; Kato, Yasuko; Ohkawa, Yasuyuki; Sato, Tetsuya; Suyama, Mikita; Kimura, Hiroshi; Yamaguchi, Masamitsu

    2015-11-01

    Post-translational modification of the histone plays important roles in epigenetic regulation of various biological processes. Among the identified histone methyltransferases (HMTases), G9a is a histone H3 Lys 9 (H3K9)-specific example active in euchromatic regions. Drosophila G9a (dG9a) has been reported to feature H3K9 dimethylation activity in vivo. Here, we show that the time required for hatching of a homozygous dG9a null mutant and heteroallelic combination of dG9a null mutants is delayed, suggesting that dG9a is at least partially responsible for progression of embryogenesis. Immunocytochemical analyses of the wild-type and the dG9a null mutant flies indicated that dG9a localizes in cytoplasm up to nuclear division cycle 7 where it is likely responsible for di-methylation of nucleosome-free H3K9. From cycles 8-11, dG9a moves into the nucleus and is responsible for di-methylating H3K9 in nucleosomes. RNA-sequence analysis utilizing early wild-type and dG9a mutant embryos showed that dG9a down-regulates expression of genes responsible for embryogenesis. RNA fluorescent in situ hybridization analysis further showed temporal and spatial expression patterns of these mRNAs did not significantly change in the dG9a mutant. These results indicate that dG9a controls transcription levels of some zygotic genes without changing temporal and spatial expression patterns of the transcripts of these genes.

  20. Coronal Emission from dG Halo Stars

    NASA Technical Reports Server (NTRS)

    Mushotzky, Richard (Technical Monitor); Harnden, F. R.

    2005-01-01

    The halo dG star HD 114762 was observed with the XMM-Newton satellite on 28-29 June 2004, during orbit 834, and the data were processed using the XMM-Newton Science Analysis System (SAS), version 6.0.0. Somewhat surprisingly, the target was NOT detected during this approx.30 ks exposure, which yielded instead a count rate upper limit of less than 0.0041 cts/s. We computed an X-ray flux upper limit by assuming a Raymond-Smith thermal spectrum of coronal temperature 1 million degrees K, typical of quiet old stars, a hydrogen column density of 2-10$^{19)$ cm$^{-2)$ and sub-solar abundances of 0.2. Our calculated X-ray luminosity upper limit in the 0.25-7.8 keV band is L$_x < 4.95 $\\time$10$^{26)$ erg/s, where we have assumed a stellar distance of 28 pc. This relatively low upper limit has implications for the capability of metal poor stars to host solar-like dynamos, as we will report in a forthcoming paper (now in preparation).

  1. [Biobanks European infrastructure].

    PubMed

    Kinkorová, Judita; Topolčan, Ondřej

    2016-01-01

    Biobanks are structured repositories of human tissue samples connected with specific information. They became an integral part of personalized medicine in the new millennium. At the European research area biobanks are isolated not well coordinated and connected to the network. European commission supports European infrastructure BBMRI-ERIC (Biobanks and Biomolecular Resources Research Infrastructure European Research Infrastructure Consortium), consortium of 54 members with more than 225 associated organizations, largely biobanks from over 30 countries. The aim is to support biomedical research using stored samples. Czech Republic is a member of the consortium as a national node BBMRI_CZ, consisting of five partners.

  2. 2DG suppresses the in vivo anti-tumor efficacy of erlotinib in HNSCC cells

    PubMed Central

    Sobhakumari, Arya; Orcutt, Kevin; Love-Homan, Laurie; Kowalski, Christopher; Parsons, Arlene; Knudson, C. Michael; Simons, Andrean L.

    2017-01-01

    Poor tumor response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) is a significant challenge for effective treatment of head and neck squamous cell carcinoma (HNSCC). Therefore, strategies that may increase tumor response to EGFR TKIs are warranted in order to improve HNSCC patient treatment and overall survival. HNSCC tumors are highly glycolytic and increased EGFR signaling has been found to promote glucose metabolism through various mechanisms. We have previously shown that inhibition of glycolysis with 2-deoxy-D-glucose (2DG) significantly enhanced the antitumor effects of cisplatin and radiation which are commonly used to treat HNSCC. The goal of the current studies is to determine if 2DG will enhance the anti-tumor activity of the EGFR TKI erlotinib in HNSCC. Erlotinib transiently suppressed glucose consumption accompanied by alterations in pyruvate kinase M2 (PKM2) expression. 2DG enhanced the cytotoxic effect of erlotinib in vitro but reversed the anti-tumor effect of erlotinib in vivo. 2DG altered the N-glycosylation status of EGFR and induced the endoplasmic reticulum (ER) stress markers CHOP and BiP in vitro. Additionally, the effects of 2DG+erlotinib on cytotoxicity and ER stress in vitro were reversed by mannose but not glucose or antioxidant enzymes. Lastly, the protective effect of 2DG on erlotinib-induced cytotoxicity in vivo was reversed by chloroquine. Altogether, 2DG suppressed the anti-tumor efficacy of erlotinib in a HNSCC xenograft mouse model which may be due to increased cytoprotective autophagy mediated by ER stress activation. PMID:27178822

  3. A New Discontinuous Galerkin Method for Convection-Diffusion Problems: The Gradient-Recovery DG Method

    NASA Astrophysics Data System (ADS)

    Johnson, Philip; Johnsen, Eric

    2016-11-01

    The Discontinuous Galerkin (DG) numerical method, while well-suited for hyperbolic PDE systems such as the Euler equations, is not naturally competitive for convection-diffusion systems, such as the Navier-Stokes equations. Where the DG weak form of the Euler equations depends only on the field variables for calculation of numerical fluxes, the traditional form of the Navier-Stokes equations requires calculation of the gradients of field variables for flux calculations. It is this latter task for which the standard DG discretization is ill-suited, and several approaches have been proposed to treat the issue. The most popular strategy for handling diffusion is the "mixed" approach, where the solution gradient is constructed from the primal as an auxiliary. We designed a new mixed approach, called Gradient-Recovery DG; it uses the Recovery concept of Van Leer & Nomura with the mixed approach to produce a scheme with excellent stability, high accuracy, and unambiguous implementation when compared to typical mixed approach concepts. In addition to describing the scheme, we will perform analysis with comparison to other DG approaches for diffusion. Gas dynamics examples will be presented to demonstrate the scheme's capabilities.

  4. [Effects of intergenic interaction of the high pigmentation gene hp-2(dg) (high pigment-2 dark green) with the gene B (beta-carotene) in tomato].

    PubMed

    Kuzemenskiĭ, A V

    2008-01-01

    It was shown that during intergenic interaction of genes hp-2(dg) and B in dihomozygote an additive factor is formed activating biogenesis of beta-carotene in tomato fruits. In the genotype B/B//hp-2(dg)/hp-2(dg) there is preserved the positive effects of the gene hp-2(dg) on the content of ascorbic acid and the negative one on the content of titrated acids. With this stabilization of the gene hp-2(dg) genetic depression is observed, which is manifested in the increased productivity of B/B//hp-2(dg)/hp-2(dg)-genotypes.

  5. Benchmarking in European Higher Education: A Step beyond Current Quality Models

    ERIC Educational Resources Information Center

    Burquel, Nadine; van Vught, Frans

    2010-01-01

    This paper presents the findings of a two-year EU-funded project (DG Education and Culture) "Benchmarking in European Higher Education", carried out from 2006 to 2008 by a consortium led by the European Centre for Strategic Management of Universities (ESMU), with the Centre for Higher Education Development, UNESCO-CEPES, and the…

  6. Accurate treatment of interface roughness in nanoscale DG MOSFETs using non-equilibrium Green's functions

    NASA Astrophysics Data System (ADS)

    Fonseca, James; Kaya, Savas

    2004-11-01

    In the sub-50-nm scale, the aggressive scaling of MOSFETs is expected to culminate in dual-gate (DG) architectures on SOI substrates. DG MOSFETs are widely accepted to be the ultimate design that silicon can deliver in terms of on and off currents. So far, the design efforts on these novel structures have concentrated on ideal geometries and doping profiles. However, at nanometer scale, devices fabricated with lithography and etching techniques cannot deliver perfect reproductions of the ideal design and suffer significantly from fluctuation effects associated with random doping and interfaces. While the former is less important in undoped, thin-body architecture, the interface roughness is a crucial factor in DG MOSFET performance, as indicated by the International Technology Roadmap for Semiconductors.

  7. Commissioning HVAC systems

    SciTech Connect

    Schiess, K.

    1995-12-01

    In recent years, commissioning has been viewed as a separate process that had to be specified and implemented by a specialized entity. This article discusses commissioning in the HVAC field and looks at it from an international perspective. The author has worked in Europe, South Africa (British system) and the USA. The differences between the British and the American methods of commissioning are discussed, with examples given where the American way was unsuccessful. It is the design engineer`s job to test and accept (commission) an installation after the contractor has demonstrated the performance to the satisfaction of the design engineer. Once the plant is commissioned, it is put into service.

  8. DG-FDF solver for large eddy simulation of compressible flows

    NASA Astrophysics Data System (ADS)

    Sammak, Shervin; Brazell, Michael; Mavriplis, Dimitri; Givi, Peyman

    2016-11-01

    A new computational scheme is developed for large eddy simulation (LES) of compressible turbulent flows with the filtered density function (FDF) subgrid scale closure. This is a hybrid scheme, combining the discontinuous Galerkin (DG) Eulerian solver with a Lagrangian Monte Carlo FDF simulator. The methodology is shown to be suitable for LES, as a larger portion of the resolved energy is captured as the order of spectral approximation increases. Simulations are conducted of both subsonic and supersonic flows. The consistency and the overall performance of the DG-FDF solver are demonstrated, together with its shock capturing capabilities.

  9. A robust SN-DG-approximation for radiation transport in optically thick and diffusive regimes

    NASA Astrophysics Data System (ADS)

    Ragusa, J. C.; Guermond, J.-L.; Kanschat, G.

    2012-02-01

    We introduce a new discontinuous Galerkin (DG) method with reduced upwind stabilization for the linear Boltzmann equation applied to particle transport. The asymptotic analysis demonstrates that the new formulation does not suffer from the limitations of standard upwind methods in the thick diffusive regime; in particular, the new method yields the correct diffusion limit for any approximation order, including piecewise constant discontinuous finite elements. Numerical tests on well-established benchmark problems demonstrate the superiority of the new method. The improvement is particularly significant when employing piecewise constant DG approximation for which standard upwinding is known to perform poorly in the thick diffusion limit.

  10. Putting Dreyfus into Action: The European Credit Transfer System

    ERIC Educational Resources Information Center

    Markowitsch, Jorg; Luomi-Messerer, Karin; Becker, Matthias; Spottl, Georg

    2008-01-01

    Purpose: The purpose of this article is to look closely at the development of a European Credit Transfer System for Vocational Education and Training (ECVET). The European Commission, together with the member States, are working on it and several pilot projects have been initiated within the Leonardo da Vinci Programme of the European Commission.…

  11. ETUDE - European Trade Union Distance Education.

    ERIC Educational Resources Information Center

    Creanor, Linda; Walker, Steve

    2000-01-01

    Describes transnational distance learning activities among European trade union educators carried out as part of the European Trade Union Distance Education (ETUDE) project, supported by the European Commission. Highlights include the context of international trade union distance education; tutor training course; tutors' experiences; and…

  12. Long-term Optical Activity of the Hard X-ray Flaring Star DG CVn

    NASA Astrophysics Data System (ADS)

    Šimon, V.

    2017-04-01

    DG CVn is a young late-type star which displayed an X-ray and optical superflare in 2014. This paper presents an analysis of the long-term activity of this object in the optical band. I used the photographic data from DASCH (Digital Access to a Sky Century @ Harvard). These measurements from the years 1895-1989 cover the blue spectral region. CCD V-band ASAS data were used for several UV Cet-type stars to place the activity of DG CVn in the context of flaring stars. I show that three large brightenings (flares) of DG CVn by more than 1 mag were detected on the DASCH plates. The character of the long-term activity (regarding the histogram of brightness) of DG CVn is compatible with those of flaring stars UV Cet and V371 Ori. The flares brighter than ˜ 0.4 mag represent less than 1 percent of the observed data in all three objects

  13. 77 FR 70204 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on December 14, 2012, in...

  14. 78 FR 12412 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... From the Federal Register Online via the Government Publishing Office ] SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on March 21, 2013, in...

  15. 78 FR 32295 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on June 20, 2013, in...

  16. HiCoDG: A Hierarchical Data-Gathering Scheme Using Cooperative Multiple Mobile Elements †

    PubMed Central

    Van Le, Duc; Oh, Hoon; Yoon, Seokhoon

    2014-01-01

    In this paper, we study mobile element (ME)-based data-gathering schemes in wireless sensor networks. Due to the physical speed limits of mobile elements, the existing data-gathering schemes that use mobile elements can suffer from high data-gathering latency. In order to address this problem, this paper proposes a new hierarchical and cooperative data-gathering (HiCoDG) scheme that enables multiple mobile elements to cooperate with each other to collect and relay data. In HiCoDG, two types of mobile elements are used: the mobile collector (MC) and the mobile relay (MR). MCs collect data from sensors and forward them to the MR, which will deliver them to the sink. In this work, we also formulated an integer linear programming (ILP) optimization problem to find the optimal trajectories for MCs and the MR, such that the traveling distance of MEs is minimized. Two variants of HiCoDG, intermediate station (IS)-based and cooperative movement scheduling (CMS)-based, are proposed to facilitate cooperative data forwarding from MCs to the MR. An analytical model for estimating the average data-gathering latency in HiCoDG was also designed. Simulations were performed to compare the performance of the IS and CMS variants, as well as a multiple traveling salesman problem (mTSP)-based approach. The simulation results show that HiCoDG outperforms mTSP in terms of latency. The results also show that CMS can achieve the lowest latency with low energy consumption. PMID:25526356

  17. HiCoDG: a hierarchical data-gathering scheme using cooperative multiple mobile elements.

    PubMed

    Van Le, Duc; Oh, Hoon; Yoon, Seokhoon

    2014-12-17

    In this paper, we study mobile element (ME)-based data-gathering schemes in wireless sensor networks. Due to the physical speed limits of mobile elements, the existing data-gathering schemes that use mobile elements can suffer from high data-gathering latency. In order to address this problem, this paper proposes a new hierarchical and cooperative data-gathering (HiCoDG) scheme that enables multiple mobile elements to cooperate with each other to collect and relay data. In HiCoDG, two types of mobile elements are used: the mobile collector (MC) and the mobile relay (MR). MCs collect data from sensors and forward them to the MR, which will deliver them to the sink. In this work, we also formulated an integer linear programming (ILP) optimization problem to find the optimal trajectories for MCs and the MR, such that the traveling distance of MEs is minimized. Two variants of HiCoDG, intermediate station (IS)-based and cooperative movement scheduling (CMS)-based, are proposed to facilitate cooperative data forwarding from MCs to the MR. An analytical model for estimating the average data-gathering latency in HiCoDG was also designed. Simulations were performed to compare the performance of the IS and CMS variants, as well as a multiple traveling salesman problem (mTSP)-based approach. The simulation results show that HiCoDG outperforms mTSP in terms of latency. The results also show that CMS can achieve the lowest latency with low energy consumption.

  18. Guidelines for residential commissioning

    SciTech Connect

    Wray, Craig P.; Walker, Iain S.; Sherman, Max H.

    2003-01-31

    Currently, houses do not perform optimally or even as many codes and forecasts predict, largely because they are field assembled and there is no consistent process to identify problems or to correct them. Residential commissioning is a solution to this problem. This guide is the culmination of a 30-month project that began in September 1999. The ultimate objective of the project is to increase the number of houses that undergo commissioning, which will improve the quality, comfort, and safety of homes for California citizens. The project goal is to lay the groundwork for a residential commissioning industry in California focused on end-use energy and non-energy issues. As such, we intend this guide to be a beginning and not an end. Our intent is that the guide will lead to the programmatic integration of commissioning with other building industry processes, which in turn will provide more value to a single site visit for people such as home energy auditors and raters, home inspectors, and building performance contractors. Project work to support the development of this guide includes: a literature review and annotated bibliography, which facilitates access to 469 documents related to residential commissioning published over the past 20 years (Wray et al. 2000), an analysis of the potential benefits one can realistically expect from commissioning new and existing California houses (Matson et al. 2002), and an assessment of 107 diagnostic tools for evaluating residential commissioning metrics (Wray et al. 2002). In this guide, we describe the issues that non-experts should consider in developing a commissioning program to achieve the benefits we have identified. We do this by providing specific recommendations about: how to structure the commissioning process, which diagnostics to use, and how to use them to commission new and existing houses. Using examples, we also demonstrate the potential benefits of applying the recommended whole-house commissioning approach to

  19. The Building Commissioning Handbook.

    ERIC Educational Resources Information Center

    Heinz, John A.; Casault, Rick

    This book discusses building commissioning, which is the process of certifying that a new facility meets the required specifications. As buildings have become more complex, the traditional methods for building start-up and final acceptance have been proven inadequate, and building commissioning has been developed, which often necessitates the use…

  20. Commissioning of HVAC systems

    SciTech Connect

    Schiess, K.

    1995-06-01

    In recent years various presentation and discussions have taken place which looked at commissioning as a separate process that had to be specified and implemented by a specialized entity in a project. This presentation discusses commissioning in the HVAC field and looks at it from an international perspective. The author has worked in Europe, South Africa (British system) and in the USA. The differences are discussed between the British and the American methods with some examples where the American way of commissioning was unsuccessful. The conclusion is that it is the design engineer`s job to test and accept (commission) an installation after the contractor has demonstrated the performance to the satisfaction of the design engineer. Once the plant is commissioned, it is put into service.

  1. Screening for gestational diabetes in Europe: where do we stand and how to move forward?: A scientific paper commissioned by the European Board & College of Obstetrics and Gynaecology (EBCOG).

    PubMed

    Benhalima, Katrien; Damm, Peter; Van Assche, André; Mathieu, Chantal; Devlieger, Roland; Mahmood, Tahir; Dunne, Fidelma

    2016-06-01

    The incidence of gestational diabetes (GDM) is rising globally and it represents an important modifiable risk factor for adverse pregnancy outcomes. GDM is also associated with negative long-term health outcomes for both mothers and offspring. Acceptance and implementation of the 2013 World Health Organization (WHO) criteria varies globally and within Europe. There is at present no consensus on the optimal approach to GDM screening in Europe. More uniformity in GDM screening across Europe will lead to an opportunity for more timely diagnosis and treatment for GDM in a greater number of women. More targeted research is necessary to evaluate optimal screening strategies based on the 2013 WHO criteria across different European populations with a focus on implementation strategy. Future research should address these important questions so that solid recommendations for GDM screening can be made to European health organizations based on screening uptake rates, maternal well-being, maternal and neonatal health outcomes, equity and cost-effectiveness. Here we describe the ongoing controversy on GDM screening and diagnosis, and provide an overview of important topics for future research concerning GDM screening in Europe.

  2. Path Searching Based Fault Automated Recovery Scheme for Distribution Grid with DG

    NASA Astrophysics Data System (ADS)

    Xia, Lin; Qun, Wang; Hui, Xue; Simeng, Zhu

    2016-12-01

    Applying the method of path searching based on distribution network topology in setting software has a good effect, and the path searching method containing DG power source is also applicable to the automatic generation and division of planned islands after the fault. This paper applies path searching algorithm in the automatic division of planned islands after faults: starting from the switch of fault isolation, ending in each power source, and according to the line load that the searching path traverses and the load integrated by important optimized searching path, forming optimized division scheme of planned islands that uses each DG as power source and is balanced to local important load. Finally, COBASE software and distribution network automation software applied are used to illustrate the effectiveness of the realization of such automatic restoration program.

  3. A combined ADER-DG and PML approach for simulating wave propagation in unbounded domains

    NASA Astrophysics Data System (ADS)

    Amler, Thomas G.; Hoteit, Ibrahim; Alkhalifah, Tariq A.

    2012-09-01

    In this work, we present a numerical approach for simulating wave propagation in unbounded domains which combines discontinuous Galerkin methods with arbitrary high order time integration (ADER-DG) and a stabilized modification of perfectly matched layers (PML). Here, the ADER-DG method is applied to Bérenger's formulation of PML. The instabilities caused by the original PML formulation are treated by a fractional step method that allows to monitor whether waves are damped in PML region. In grid cells where waves are amplified by the PML, the contribution of damping terms is neglected and auxiliary variables are reset. Results of 2D simulations in acoustic media with constant and discontinuous material parameters are presented to illustrate the performance of the method.

  4. DG-FTLE: Lagrangian coherent structures with high-order discontinuous-Galerkin methods

    NASA Astrophysics Data System (ADS)

    Nelson, Daniel A.; Jacobs, Gustaaf B.

    2015-08-01

    We present an algorithm for the computation of finite-time Lyapunov exponent (FTLE) fields using discontinuous-Galerkin (dG) methods in two dimensions. The algorithm is designed to compute FTLE fields simultaneously with the time integration of dG-based flow solvers of conservation laws. Fluid tracers are initialized at Gauss-Lobatto quadrature nodes within an element. The deformation gradient tensor, defined by the deformation of the Lagrangian flow map in finite time, is determined per element with high-order dG operators. Multiple flow maps are constructed from a particle trace that is released at a single initial time by mapping and interpolating the flow map formed by the locations of the fluid tracers after finite time integration to a unit square master element and to the quadrature nodes within the element, respectively. The interpolated flow maps are used to compute forward-time and backward-time FTLE fields at several times using dG operators. For a large finite integration time, the interpolation is increasingly poorly conditioned because of the excessive subdomain deformation. The conditioning can be used in addition to the FTLE to quantify the deformation of the flow field and identify subdomains with material lines that define Lagrangian coherent structures. The algorithm is tested on three benchmarks: an analytical spatially periodic gyre flow, a vortex advected by a uniform inviscid flow, and the viscous flow around a square cylinder. In these cases, the algorithm is shown to have spectral convergence.

  5. A new approach to extracting the RF parameters of asymmetric DG MOSFETs with the NQS effect

    NASA Astrophysics Data System (ADS)

    Pati, Sudhansu Kumar; Koley, Kalyan; Dutta, Arka; Mohankumar, N.; Sarkar, Chandan Kumar

    2013-11-01

    In analog circuit design an important parameter, from the perspective of superior device performance, is linearity. The DG MOSFET in asymmetric mode operation has been found to present a better linearity. In addition to that it provides, at the discretion of analog circuit designer, an additional degree of freedom, by providing independent bias control for the front and the back gates. Here a non-quasi-static (NQS) small signal model for DGMOSFET with asymmetric gate bias is proposed for extracting the parameters of the device using TCAD simulations. The parameters extracted here for analysis are the intrinsic front and back gate to drain capacitance, Cgd1 and Cgd2, the intrinsic front and back distributed channel resistance, Rgd1 and Rgd2 respectively, the transport delay, τm, and the inductance, Lsd. The parameter extraction model for an asymmetric DG MOSFET is validated with pre-established extracted parameter data, for symmetric DG MOSFET devices, from the available literature. The device simulation is performed with respect to frequency up to 100 GHz.

  6. State Emergency Response Commissions

    EPA Pesticide Factsheets

    The Governor of each state has designated a State Emergency Response Commission (SERC) that is responsible for implementing the Emergency Planning and Community Right-to-Know Act (EPCRA) provisions within its state.

  7. Nuclear Regulatory Commission issuances

    SciTech Connect

    Not Available

    1994-03-01

    This report includes the issuances received during the specified period from Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM).

  8. Nuclear Regulatory Commission Issuances

    SciTech Connect

    1996-12-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM).

  9. Commissioning the LCLS Injector

    SciTech Connect

    Akre, R.; Dowell, D.; Emma, P.; Frisch, J.; Gilevich, S.; Hays, G.; Hering, Ph.; Iverson, R.; Limborg-Deprey, C.; Loos, H.; Miahnahri, A.; Schmerge, J.; Turner, J.; Welch, J.; White, W.; Wu, J.; /SLAC

    2007-11-28

    The Linac Coherent Light Source (LCLS) is a SASE x-ray Free-Electron Laser (FEL) project presently under construction at SLAC. The injector section, from drive laser and RF photocathode gun through first bunch compressor chicane, was installed in fall 2006. Initial system commissioning with an electron beam was completed in August 2007, with the goal of a 1.2-micron emittance in a 1-nC bunch clearly demonstrated. The second phase of commissioning, including second bunch compressor and full linac, is planned for 2008, with FEL commissioning in 2009. We report experimental results and experience gained in the first phase of commissioning, including the photo-cathode drive laser, RF gun, photocathode, S-band and X-band RF systems, first bunch compressor, and the various beam diagnostics.

  10. Optimization of a stand-alone Solar PV-Wind-DG Hybrid System for Distributed Power Generation at Sagar Island

    NASA Astrophysics Data System (ADS)

    Roy, P. C.; Majumder, A.; Chakraborty, N.

    2010-10-01

    An estimation of a stand-alone solar PV and wind hybrid system for distributed power generation has been made based on the resources available at Sagar island, a remote area distant to grid operation. Optimization and sensitivity analysis has been made to evaluate the feasibility and size of the power generation unit. A comparison of the different modes of hybrid system has been studied. It has been estimated that Solar PV-Wind-DG hybrid system provides lesser per unit electricity cost. Capital investment is observed to be lesser when the system run with Wind-DG compared to Solar PV-DG.

  11. Commission 51: Bioastronomy

    NASA Astrophysics Data System (ADS)

    Irvine, William; Ehrenfreund, Pascale; Boss, Alan; Cosmovici, Cristiano; Kwok, Sun; Levasseur-Regourd, Anny-Chantal; Morrison, David; Udry, Stephane

    2010-05-01

    Commission 51 met on August 12, 2009. Outgoing President Alan Boss chaired the meeting, and there were several dozen members present, including incoming President William Irvine, incoming Vice President Pascale Ehrenfreund, and outgoing Past President Karen Meech. Commission 51 (C51) was re-authorized for a term of six more years at the 2006 Prague General Assembly of the IAU, and hence comes up for renewal at the 2012 IAU General Assembly in Beijing, China.

  12. SPEAR3 Commissioning

    SciTech Connect

    Harkay, K.; Sajaev, V.; Boland, M.J.; Tan, Y.E.; Krinsky, S.; Podobedov, B.; Decking, W.; Ropert, A.; Byrd, J.M.; Robin, D.; Scarvie, T.; Steier, C.; Fedurin, M.G.; Jines, P.; Chang, H.-P.; Kuo, C.-C.; Tsai, H.-J.; Yoon, M.H.; Boge, M.; Allison, S.; Bellomo, P.; /SLAC, SSRL /SOLEIL, Saint-Aubin

    2005-05-09

    The successful commissioning of the new SPEAR3 light source at the Stanford Synchrotron Radiation Laboratory (SSRL) will be reviewed. Orbit control, beam-based alignment, and an orbit interlock were commissioned. Orbit motion was characterized as a function of frequency. The linear optics was corrected for ID focusing and coupling errors. The nonlinear optics were investigated with dynamic aperture measurements as a function of energy and tune.

  13. The European Spallation Source

    SciTech Connect

    Peggs, S; Eshraqi, M; Hahn, H; Jansson, A; Lindroos, M; Ponton, A; Rathsman, K; Trahern, G; Bousso, S; Calaga, R; Devanz, G; Duperrier, R D; Eguia, J; Gammino, S; Moller, S P; Oyon, C; Ruber, R.J.M.Y.; Satogata, T

    2011-03-01

    The European Spallation Source (ESS) is a 5 MW, 2.5 GeV long pulse proton linac, to be built and commissioned in Lund, Sweden. The Accelerator Design Update (ADU) project phase is under way, to be completed at the end of 2012 by the delivery of a Technical Design Report. Improvements to the 2003 ESS design will be summarised, and the latest design activities will be presented.

  14. A comparison of Fuel Cell Testing protocols - A case study: Protocols used by the U.S. Department of Energy, European Union, International Electrotechnical Commission/Fuel Cell Testing and Standardization Network, and Fuel Cell Technical Team

    NASA Astrophysics Data System (ADS)

    Bloom, Ira; Walker, Lee K.; Basco, John K.; Malkow, Thomas; Saturnio, Antonio; De Marco, Giancarlo; Tsotridis, Georgios

    2013-12-01

    Argonne National Laboratory (Argonne) and the Joint Research Centre-Institute for Energy and Transport (JRC-IET) collaborated to understand the aging behavior of polymer-electrolyte membrane stacks when operated under different duty cycles. The duty cycles were that used by the U.S. Department of Energy (DST) and the US Fuel Cell Council; the New European Drive Cycle (ECE R15); that used in IEC-TS62282-7-1 (IEC) and Fuel Cell Testing and Standardization Network; and the one proposed by the US Driving Research and Innovation for Vehicle Efficiency and Energy Sustainability Fuel Cell Technical Team (FCTT). The stacks were cycled using the duty profile in each protocol for 200 h; stack performance was measured every 100 h. Analysis of the relative changes in the average cell potentials at 180 A showed that the rate of performance decline could be ordered as IEC > ECE R15, the latter being slightly greater than or approximately equal to DST and FCTT. Comparing this ordering to the length of time at full power in the duty cycle with the degradation rates shows that they are related. Most likely, the underlying cause of performance decline can be attributed to the manner in which the product water interacts with the stack components.

  15. Commissioning Experience of SNS

    SciTech Connect

    Plum, Michael A

    2007-07-01

    The Spallation Neutron Source accelerator complex consists of a 2.5 MeV H{sup -} front-end injector system, a 186 MeV normal-conducting linear accelerator, a 1 GeV superconducting linear accelerator, an accumulator ring, and associated beam transport lines. The linac was commissioned in five discrete runs, starting in 2002 and completed in 2005. The accumulator ring and associated beam transport lines were commissioned in two runs in January-February and April 2006. With the completed commissioning of the SNS accelerator, the facility has begun initial low-power operations. In the course of beam commissioning, most beam performance parameters and beam intensity goals have been achieved at low duty factor. A number of beam dynamics measurements have been performed, including emittance evolution, transverse coupling in the ring, beam instability thresholds, and beam distributions on the target. The commissioning results, achieved beam performance and initial operating experience of the SNS linac will be presented.

  16. A Novel Rhamnose-Rich Hetero-exopolysaccharide Isolated from Lactobacillus paracasei DG Activates THP-1 Human Monocytic Cells.

    PubMed

    Balzaretti, Silvia; Taverniti, Valentina; Guglielmetti, Simone; Fiore, Walter; Minuzzo, Mario; Ngo, Hansel N; Ngere, Judith B; Sadiq, Sohaib; Humphreys, Paul N; Laws, Andrew P

    2017-02-01

    Lactobacillus paracasei DG is a bacterial strain with recognized probiotic properties and is used in commercial probiotic products. However, the mechanisms underlying its probiotic properties are mainly unknown. In this study, we tested the hypothesis that the ability of strain DG to interact with the host is at least partly associated with its ability to synthesize a surface-associated exopolysaccharide (EPS). Comparative genomics revealed the presence of putative EPS gene clusters in the DG genome; accordingly, EPS was isolated from the surface of the bacterium. A sample of the pure EPS from strain DG (DG-EPS), upon nuclear magnetic resonance (NMR) and chemical analyses, was shown to be a novel branched hetero-EPS with a repeat unit composed of l-rhamnose, d-galactose, and N-acetyl-d-galactosamine in a ratio of 4:1:1. Subsequently, we demonstrated that DG-EPS displays immunostimulating properties by enhancing the gene expression of the proinflammatory cytokines tumor necrosis factor alpha (TNF-α) and interleukin 6 (IL-6), and particularly that of the chemokines IL-8 and CCL20, in the human monocytic cell line THP-1. In contrast, the expression of the cyclooxygenase enzyme COX-2 was not affected. In conclusion, DG-EPS is a bacterial macromolecule with the ability to boost the immune system either as a secreted molecule released from the bacterium or as a capsular envelope on the bacterial cell wall. This study provides additional information about the mechanisms supporting the cross talk between L. paracasei DG and the host.

  17. A quality assessment of the MARS crop yield forecasting system for the European Union

    NASA Astrophysics Data System (ADS)

    van der Velde, Marijn; Bareuth, Bettina

    2015-04-01

    Timely information on crop production forecasts can become of increasing importance as commodity markets are more and more interconnected. Impacts across large crop production areas due to (e.g.) extreme weather and pest outbreaks can create ripple effects that may affect food prices and availability elsewhere. The MARS Unit (Monitoring Agricultural ResourceS), DG Joint Research Centre, European Commission, has been providing forecasts of European crop production levels since 1993. The operational crop production forecasting is carried out with the MARS Crop Yield Forecasting System (M-CYFS). The M-CYFS is used to monitor crop growth development, evaluate short-term effects of anomalous meteorological events, and provide monthly forecasts of crop yield at national and European Union level. The crop production forecasts are published in the so-called MARS bulletins. Forecasting crop yield over large areas in the operational context requires quality benchmarks. Here we present an analysis of the accuracy and skill of past crop yield forecasts of the main crops (e.g. soft wheat, grain maize), throughout the growing season, and specifically for the final forecast before harvest. Two simple benchmarks to assess the skill of the forecasts were defined as comparing the forecasts to 1) a forecast equal to the average yield and 2) a forecast using a linear trend established through the crop yield time-series. These reveal a variability in performance as a function of crop and Member State. In terms of production, the yield forecasts of 67% of the EU-28 soft wheat production and 80% of the EU-28 maize production have been forecast superior to both benchmarks during the 1993-2013 period. In a changing and increasingly variable climate crop yield forecasts can become increasingly valuable - provided they are used wisely. We end our presentation by discussing research activities that could contribute to this goal.

  18. High Efficiency Apoptosis Induction in Breast Cancer Cell Lines by MLN4924/2DG Co-Treatment.

    PubMed

    Oladghaffari, Maryam; Islamian, Jalil Pirayesh; Baradaran, Behzad; Monfared, Ali Shabestani; Farajollahi, Alireza; Shanehbandi, Dariush; Mohammadi, Mohsen

    2015-01-01

    2-deoxy-D-Glucose (2DG) causes cytotoxicity in cancer cells by disrupting thiol metabolism. It is an effective component in therapeutic strategies. It targets the metabolism of cancer cells with glycolysis inhibitory activity. On the other hand, MLN4924, a newly discovered investigational small molecule inhibitor of NAE (NEDD8 activating enzyme), inactivates SCF E3 ligase and causes accumulation of its substrates which triggers apoptosis. Combination of these components might provide a more efficient approach to treatment. In this research, 2DG and MLN4924 were co-applied to breast cancer cells (MCF-7 and SKBR-3) and cytotoxic and apoptotic activity were evaluated the by Micro culture tetrazolium test (MTT), TUNEL and ELISA methods. Caspase3 and Bcl2 genes expression were evaluated by real time Q-PCR methods. The results showed that MLN4924 and MLN4924/2DG dose-dependently suppressed the proliferation of MCF7 and SKBR-3 cells. Cell survival of breast cancer cells exposed to the combination of 2DG/MLN4924 was decreased significantly compared to controls (p<0.05), while 2DG and MLN4924 alone had less pronounced effects on the cells. The obtained results suggest that 2DG/MLN4924 is much more efficient in breast cancer cell lines with enhanced cytotoxicity via inducing a apoptosis cell signaling gene, caspase-3.

  19. Commissioning dose computation models for spot scanning proton beams in water for a commercially available treatment planning system

    PubMed Central

    Zhu, X. R.; Poenisch, F.; Lii, M.; Sawakuchi, G. O.; Titt, U.; Bues, M.; Song, X.; Zhang, X.; Li, Y.; Ciangaru, G.; Li, H.; Taylor, M. B.; Suzuki, K.; Mohan, R.; Gillin, M. T.; Sahoo, N.

    2013-01-01

    Purpose: To present our method and experience in commissioning dose models in water for spot scanning proton therapy in a commercial treatment planning system (TPS). Methods: The input data required by the TPS included in-air transverse profiles and integral depth doses (IDDs). All input data were obtained from Monte Carlo (MC) simulations that had been validated by measurements. MC-generated IDDs were converted to units of Gy mm2/MU using the measured IDDs at a depth of 2 cm employing the largest commercially available parallel-plate ionization chamber. The sensitive area of the chamber was insufficient to fully encompass the entire lateral dose deposited at depth by a pencil beam (spot). To correct for the detector size, correction factors as a function of proton energy were defined and determined using MC. The fluence of individual spots was initially modeled as a single Gaussian (SG) function and later as a double Gaussian (DG) function. The DG fluence model was introduced to account for the spot fluence due to contributions of large angle scattering from the devices within the scanning nozzle, especially from the spot profile monitor. To validate the DG fluence model, we compared calculations and measurements, including doses at the center of spread out Bragg peaks (SOBPs) as a function of nominal field size, range, and SOBP width, lateral dose profiles, and depth doses for different widths of SOBP. Dose models were validated extensively with patient treatment field-specific measurements. Results: We demonstrated that the DG fluence model is necessary for predicting the field size dependence of dose distributions. With this model, the calculated doses at the center of SOBPs as a function of nominal field size, range, and SOBP width, lateral dose profiles and depth doses for rectangular target volumes agreed well with respective measured values. With the DG fluence model for our scanning proton beam line, we successfully treated more than 500 patients from

  20. 77 FR 28420 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on June 7, 2012, in Binghamton,...

  1. Analysis of waste hierarchy in the European waste directive 2008/98/EC.

    PubMed

    Gharfalkar, Mangesh; Court, Richard; Campbell, Callum; Ali, Zulfiqur; Hillier, Graham

    2015-05-01

    Loss of recoverable resources in linear resource flow systems is likely to contribute to the depletion of natural resources and environmental degradation. The 'waste hierarchy' in the European Commission's latest Waste Framework Directive 2008/98/EC (WFD2008) makes recommendations on how to address this issue. The WFD2008 is analysed in this work for its adequacy in ensuring return of 'recoverable waste' as a 'resource' into the productive system. Despite the release of guidance documents by the DG Environment, DEFRA and WRAP UK on the interpretation of key provisions of the WFD2008, lack of clarity still exists around the WFD2008 'waste hierarchy'. There is also an overlap between measures such as 'prevention' and 'reduction', 'preparing for reuse' and 'reuse' and lack of clarity on why the measure of 'reuse' is included in the WFD2008 definition of 'prevention'. Finally, absence of the measures of 'recovery' and 'reuse' from the WFD2008 'waste hierarchy' reduces its effectiveness as a resource efficiency tool. Without clarity on the WFD2008 'waste hierarchy', it is challenging for decision makers to take direct action to address inefficiencies existing within their operations or supply chains. This paper proposes the development of an alternative 'hierarchy of resource use' and alternative 'definitions' that attempt to fill identified gaps in the WFD2008 and bring clarity to the key measures of waste prevention, reduction and recovery. This would help the key stakeholders in driving resource effectiveness, which in turn would assist in conservation of natural resources and prevention of environmental degradation.

  2. DG Connect Funded Projects on Information and Communication Technologies (ICT) for Old Age People: Beyond Silos, CareWell and SmartCare.

    PubMed

    Keijser, W; de Manuel-Keenoy, E; d'Angelantonio, M; Stafylas, P; Hobson, P; Apuzzo, G; Hurtado, M; Oates, J; Bousquet, J; Senn, A

    2016-01-01

    Information and communication technologies (ICT) are promising for the long-term care of older and frequently frail people. These innovations can improve health outcomes, quality of life and efficiency of care processes, while supporting independent living. However, they may be disruptive innovations. As all European member states are facing an increasing complexity of health and social care, good practices in ICT should be identified and evaluated. Three projects funded by DG CNECT are related to Active and Healthy Ageing (AHA) and frailty: (i) BeyondSilos, dealing with independent living and integrated services, (ii) CareWell, providing integrated care coordination, patient empowerment and home support and (iii) SmartCare, proposing a common set of standard functional specifications for an ICT platform enabling the delivery of integrated care to older patients. The three projects described in this paper provide a unique pan-European research field to further study implementation efforts and outcomes of new technologies. Below, based on a description of the projects, the authors display four domains that are in their views fundamental for in-depth exploration of heterogeneity in the European context: 1. Definition of easily transferable, high level pathways with solid evidence-base; 2. Change management in implementing ICT enabled integrated care; 3. Evaluation and data collection methodologies based on existing experience with MAST and MEDAL methodologies; and 4. Construction of new models for delivery of health and social care. Understanding complementarity, synergies and differences between the three unique projects can help to identify a more effective roll out of best practices within a varying European context.

  3. Commission on Liberal Learning

    ERIC Educational Resources Information Center

    Hazzard, George W.

    1976-01-01

    Study emphasis within the Commission on Liberal Learning during the year was on the role of liberal education in the society of the future. The relationship of undergraduate liberal education to the world macro-problem--population growth, industrial production, food, materials and energy scarcities, pollution and environmental degradation--was…

  4. Nuclear Regulatory Commission issuances

    SciTech Connect

    1997-11-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  5. Nuclear Regulatory Commission Issuances

    SciTech Connect

    Not Available

    1994-10-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  6. Nuclear Regulatory Commission issuances

    SciTech Connect

    1997-09-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  7. Legal Commission Report

    ERIC Educational Resources Information Center

    American Indian Journal, 1977

    1977-01-01

    The Legal Commission of the International Non-Governmental Organizations Conference on Discrimination Against Indigenous Populations adopted the following agenda: legal status of indigenous populations; the land question; indigenous laws and courts; discrimination against indigenous peoples in existing laws and their application; and creation of…

  8. Implications of 1992 for European Telecommunications.

    ERIC Educational Resources Information Center

    Muller, Jurgen

    This paper analyzes the effect of the unified single market of 1992 on European telecommunications. The major policy aspects of the European Economic Commission's Green Paper on "The Development of the Common Market for Telecommunications Services and Equipment" are highlighted, and the effects of these policies in the equipment market…

  9. Attitudes of Europeans toward Age.

    ERIC Educational Resources Information Center

    Ageing International, 1993

    1993-01-01

    Two Commission of European Communities surveys of people over age 15 and of those over 60 demonstrated a widespread belief that older people deserve public support and services and face employment discrimination. Socioeconomic factors influenced older people's sense of security and life satisfaction. Positive intergenerational attitudes appeared.…

  10. Application of the DG-1199 methodology to the ESBWR and ABWR.

    SciTech Connect

    Kalinich, Donald A.; Gauntt, Randall O.; Walton, Fotini

    2010-09-01

    Appendix A-5 of Draft Regulatory Guide DG-1199 'Alternative Radiological Source Term for Evaluating Design Basis Accidents at Nuclear Power Reactors' provides guidance - applicable to RADTRAD MSIV leakage models - for scaling containment aerosol concentration to the expected steam dome concentration in order to preserve the simplified use of the Accident Source Term (AST) in assessing containment performance under assumed design basis accident (DBA) conditions. In this study Economic and Safe Boiling Water Reactor (ESBWR) and Advanced Boiling Water Reactor (ABWR) RADTRAD models are developed using the DG-1199, Appendix A-5 guidance. The models were run using RADTRAD v3.03. Low Population Zone (LPZ), control room (CR), and worst-case 2-hr Exclusion Area Boundary (EAB) doses were calculated and compared to the relevant accident dose criteria in 10 CFR 50.67. For the ESBWR, the dose results were all lower than the MSIV leakage doses calculated by General Electric/Hitachi (GEH) in their licensing technical report. There are no comparable ABWR MSIV leakage doses, however, it should be noted that the ABWR doses are lower than the ESBWR doses. In addition, sensitivity cases were evaluated to ascertain the influence/importance of key input parameters/features of the models.

  11. Evaluation of Superimposed Sequence Components of Currents based Islanding Detection Scheme during DG Interconnections

    NASA Astrophysics Data System (ADS)

    Sareen, Karan; Bhalja, Bhavesh R.; Maheshwari, Rudra Prakash

    2016-02-01

    A new islanding detection scheme for distribution network containing different types of distributed generations (DGs) is presented in this paper. The proposed scheme is based on acquiring three phase current samples for full cycle duration of each simulation case of islanding/non-islanding conditions at the point of common coupling (PCC) of the targeted DG. Afterwards, superimposed positive & negative sequence components of current are calculated and continuously compared with pre-determined threshold values. Performance of the proposed scheme has been evaluated on diversified islanding and non-islanding events which were generated by modeling standard IEEE 34-bus system using PSCAD/EMTDC software package. The proposed scheme is capable to detect islanding condition rapidly even for perfect power balance situation for both synchronous and inverter based DGs. Furthermore, it remains stable during non-islanding events such as tripping of multiple DGs and different DG interconnection operating conditions. Therefore, the proposed scheme avoids nuisance tripping during diversified non-islanding events. At the end, comparison of the proposed scheme with the existing scheme clearly indicates its advantage over the existing scheme.

  12. Novel 2DG-based harmine derivatives for targeted cancer therapy

    NASA Astrophysics Data System (ADS)

    Wang, Aqin; Chen, Yuqi; Chen, Wei R.; Gu, Yueqing

    2013-02-01

    Harmine is a beta-carboline alkaloid from the plant Peganum harmala. These alkaloids were stimulated by their promising antitumor activities in the recent years. In this study, we designed and synthesized two harmine derivatives #1and #2 modified at position-9 of harmine with ethyl and phenylpropyl, respectively. To improve the tumor targeting capability, #1' and #2' were synthesized by conjugating 2-amino-2-deoxy-D-glucose (2DG) to the derivatives #1 and #2, respectively. The MTT assays of all these compounds in vitro against L02, HepG2 showed all compounds had low toxicity to normal cells (L02) and significantly enhanced carcinoma cell inhibitory rate compared to harmine. Cytotoxicity against liver cancer cell lines of compound #1' #2' is higher than #1 #2, and even the compound #2' is better than positive drug 5-FU. The compound #2', a novel 2DG-based harmine derivatives, could become a promising drug for targeted cancer therapy and combination therapy with other antitumor drugs.

  13. Nuclear Regulatory Commission issuances

    SciTech Connect

    1996-04-01

    This report includes the issuances received during the April 1996 reporting period from the Commission, the Atomic Safety and Licensing Boards, the Administrative Law Judges, the Directors` Decisions, and the Decisions on Petitions for Rulemaking. Included are issuances pertaining to: (1) Yankee Nuclear Power Station, (2) Georgia Tech Research Reactor, (3) River Bend Station, (4) Millstone Unit 1, (5) Thermo-Lag fire barrier material, and (6) Louisiana Energy Services.

  14. Commission 42: Close Binaries

    NASA Astrophysics Data System (ADS)

    Rucinski, Slavek M.; Ribas, Ignasi; Giménez, Alvaro; Harmanec, Petr; Hilditch, Ronald W.; Kaluzny, Janusz; Niarchos, Panayiotis; Nordström, Birgitta; Oláh, Katalin; Richards, Mercedes T.; Scarfe, Colin D.; Sion, Edward M.; Torres, Guillermo; Vrielmann, Sonja

    2010-05-01

    During the commission business session, the past President presented the new Organizing Committee which was selected by the OC through a e-mail vote conducted during the months before the Rio de Janeiro General Assembly. The new OC will consist of Ignasi Ribas (President), Mercedes Richards (Vice President), and Slavek Rucinski (Past President) with the members: David Bradstreet, Petr Harmanec, Janusz Kaluzny, Joanna Mikolajewska, Ulisse Munari, Panos Niarchos, Katalin Olah, Theo Pribulla, Colin Scarfe and Guillermo Torres.

  15. A Monte Carlo study of monoenergetic and polyenergetic normalized glandular dose (DgN) coefficients in mammography

    NASA Astrophysics Data System (ADS)

    Sarno, Antonio; Mettivier, Giovanni; Di Lillo, Francesca; Russo, Paolo

    2017-01-01

    We investigated the influence of model assumptions in GEANT4 Monte Carlo (MC) simulations for the calculation of monoenergetic and polyenergetic normalized glandular dose coefficients (DgN) in mammography, focussing on the effect of the skin thickness and composition, of the role of compression paddles and of the bremsstrahlung processes. We showed that selecting a skin thickness of 4 mm instead of 1.45 mm produced DgN values with deviations from 9% to 32% for x-ray spectra routinely adopted in mammography. Consideration of the bremsstrahlung radiation had a weak influence on monoenergetic DgN. Simulations (in the range 8-40 kVp) which included consideration of bremsstrahlung radiation, a skin thickness of 1.45 mm and a 2 mm thick compression paddles produced polyenergetic DgN coefficients up to 19% higher than corresponding literature data. Adding a 2 mm thick adipose layer between the skin layer and the radiosensitive portion of the breast produces polyenergetic DgN values up to 15% higher than those routinely adopted. These findings provide a quantitative estimate of the influence of model parameters on the calculation of the mean glandular dose in mammography.

  16. NEARTOWARN: A new EU-DG ECHO-supported project for the near-field tsunami early warning

    NASA Astrophysics Data System (ADS)

    Papadopoulos, G. A.

    2012-04-01

    The early warning for near-field (local) tsunamis, with travel times of no more than about 30 min. from the tsunami source to the closest coastal zones, is today a hot topic of great importance in the international effort to reduce the loss of human lives and to mitigate other tsunami risks. Particularly, in the Mediterranean region earthquakes, and more rarely volcanic eruptions and landslides, produce near-field tsunamis threatening nearly all the coastal zones but mainly those in the Hellenic Arc and Trench (South Peloponnese, Cyclades, Crete, Rhodes, SW Turkey), in the Corinth Gulf (Central Greece), in the Messina strait and the east Sicily (Italy) in the Ligurian Sea, the Algeria and the Balearic islands, in the west Mediterranean basin, and the Cyprus-Lebanon area in the easternmost Mediterranean. The North East Atlantic and Mediterranean Tsunami Warning System (NEAMTWS), which is under construction with the supervision of the Intergovernmental Oceanographic Commission, is oriented to issue warnings only in regional scales, that is for about 1 hour of tsunami propagation time. For near-field warning it is unrealistic to rely on a unique system for the entire basin. Instead, several local systems working on the basis of some joint principles but with local adjustements is the most promising solution. This is exactly the aim of the new project NEARToWARN (Near-field Tsunami Warning) which is supported by the EU DG-ECHO. Partnership includes the National Observatory of Athens (Coordinator, Greece), the University of Bologna (Italy), the University of Cyprus, the ACRI-ST (Sophia-Antipolis, France), the University of Cantabria (Spain) and the Municipility of Rhodes. The main concept is to develop a prototype local early tsunami warning system. To minimize the time for emergency in less than 30 sec, seismic alert devices (SED's) make the core component of the system. SED's are activated and send alerting signals as soon as a P-phase of seismic wave is detected in

  17. The Organisation and Management of a European Educational Satellite System.

    ERIC Educational Resources Information Center

    Bates, A. W.

    This paper looks at the possible roles that the European Economic Community (EEC), as a pan-European quasi-governmental institution, might play in the management and organization of a European educational satellite system. The argument is made that there is a need for the EEC Commission to play an ongoing, regulatory role in this area. An…

  18. Politics and Policies of Promoting Multilingualism in the European Union

    ERIC Educational Resources Information Center

    Romaine, Suzanne

    2013-01-01

    This article examines the politics of policies promoting multilingualism in the European Union (EU), specifically in light of the recently released European Union Civil Society Platform on Multilingualism. As the most far-reaching and ambitious policy document issued by the European Commission, the Platform warrants close scrutiny at a significant…

  19. Expert Groups in the Building of European Public Policy

    ERIC Educational Resources Information Center

    Robert, Cecile

    2012-01-01

    When it comes to building European public action, expertise is ubiquitous and polymorphic. This article intends to study the ways expertise is being used in the European Commission and the logics underlying its use. The massive use of expertise also has consequences for the practices and identities of actors with whom European institutions…

  20. Reduced Cerebral Oxygen Content in the DG and SVZ In Situ Promotes Neurogenesis in the Adult Rat Brain In Vivo.

    PubMed

    Zhang, Kuan; Zhou, Yanzhao; Zhao, Tong; Wu, Liying; Huang, Xin; Wu, Kuiwu; Xu, Lun; Li, Dahu; Liu, Shuhong; Zhao, Yongqi; Fan, Ming; Zhu, Lingling

    2015-01-01

    Neurogenesis in the adult brain occurs mainly within two neurogenic structures, the dentate gyrus (DG) of the hippocampus and the sub-ventricular zone (SVZ) of the forebrain. It has been reported that mild hypoxia promoted the proliferation of Neural Stem Cells (NSCs)in vitro. Our previous study further demonstrated that an external hypoxic environment stimulated neurogenesis in the adult rat brain in vivo. However, it remains unknown how external hypoxic environments affect the oxygen content in the brain and result in neurogenesis. Here we use an optical fiber luminescent oxygen sensor to detect the oxygen content in the adult rat brain in situ under normoxia and hypoxia. We found that the distribution of oxygen in cerebral regions is spatiotemporally heterogeneous. The Po2 values in the ventricles (45∼50 Torr) and DG (approximately 10 Torr) were much higher than those of other parts of the brain, such as the cortex and thalamus (approximately 2 Torr). Interestingly, our in vivo studies showed that an external hypoxic environment could change the intrinsic oxygen content in brain tissues, notably reducing oxygen levels in both the DG and SVZ, the major sites of adult neurogenesis. Furthermore, the hypoxic environment also increased the expression of HIF-1α and VEGF, two factors that have been reported to regulate neurogenesis, within the DG and SVZ. Thus, we have demonstrated that reducing the oxygen content of the external environment decreased Po2 levels in the DG and SVZ. This reduced oxygen level in the DG and SVZ might be the main mechanism triggering neurogenesis in the adult brain. More importantly, we speculate that varying oxygen levels may be the physiological basis of the regionally restricted neurogenesis in the adult brain.

  1. A Guide to Building Commissioning

    SciTech Connect

    Baechler, Michael C.

    2011-09-01

    Commissioning is the process of verifying that a building's heating, ventilation, and air conditioning (HVAC) and lighting systems perform correctly and efficiently. Without commissioning, system and equipment problems can result in higher than necessary utility bills and unexpected and costly equipment repairs. This report reviews the benefits of commissioning, why it is a requirement for Leadership in Energy and Environmental Design (LEED) certification, and why building codes are gradually adopting commissioning activities into code.

  2. Nuclear Regulatory Commission information digest

    SciTech Connect

    None,

    1990-03-01

    The Nuclear Regulatory Commission information digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the commission. This is an annual publication for the general use of the NRC Staff and is available to the public. The digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  3. SNS Cryogenic Systems Commissioning

    SciTech Connect

    D. Hatfield; F. Casagrande; I. Campisi; P. Gurd; M. Howell; D. Stout; H. Strong; D. Arenius; J. Creel; K. Dixon; V. Ganni; and P. Knudsen

    2005-08-29

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  4. Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Defraigne, Pascale; Manchester, Richard; Matsakis, Demetrios; Petit, Gerard; Hosokawa, Mizuhiko; Leschiutta, Sigfrid; Zhai, Zao-Cheng

    2010-05-01

    Dr R. N. Manchester and Dr M. Hosokawa have been elected as, respectively, the new President and Vice-President of the Commission for the next term, 2009-2012. Concerning the Organizing Committee (OC) Members, we welcome as new members: Felicitas Aris (BIPM, France), Philip Tuckey (LNE-SYRTE, France), Vladimir Zharov (MSU, Russia), and Shougang Zhang (NTSC, China) and we acknowledge the outgoing members: Demetrios Matsakis, Gerard Petit, Mizuhiko Hosokawa, Sigfrid Leschiutta and Zao-Cheng Zhai. P. Defraigne remains on the OC as immediate Past-President.

  5. The SNS RFQ Commissioning

    SciTech Connect

    Ratti, A.; Ayers, J.; Doolittle, L.; DiGennaro, R.; Gough, R.A.; Hoff, M.; Keller, R.; MacGill, J.; Staples, J.; Thomae, R.; Virostek, S.; Yourd, R.; Aleksandrov, A.

    2002-08-16

    LBNL has built for the Spallation Neutron Source (SNS) project a 402.5 MHz RFQ that is designed to accelerate up to 60 mA H{sup -} from 65 keV to 2.5 MeV [1]. A one millisecond pulse length at 60 Hz provides a 6% duty factor. The RFQ has now been built, conditioned at full duty factor and tested with beam. This paper will present results from the final installation, tuning and beam commissioning. Beam measurements include acceleration and transport efficiencies and transverse emittances. The LEBT optics were tuned for best results. Performance testing of the RF power distribution is also discussed here.

  6. SNS Cryogenic Systems Commissioning

    NASA Astrophysics Data System (ADS)

    Hatfield, D.; Casagrande, F.; Campisi, I.; Gurd, P.; Howell, M.; Stout, D.; Strong, H.; Arenius, D.; Creel, J.; Dixon, K.; Ganni, V.; Knudsen, P.

    2006-04-01

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  7. Thermal conductivity of diethylene glycol based magnesium-aluminum spinel (MgAl2O4-DG) nanofluids

    NASA Astrophysics Data System (ADS)

    Żyła, Gaweł; Fal, Jacek; Gizowska, Magdalena; Perkowski, Krzysztof

    2016-12-01

    The paper presents the results of measurements of the thermal conductivity of MgAl_2O_4 -DG nanofluids. The dependence of the thermal conductivity on concentration of nanoparticles in various temperatures from 293.15 to 338.15 K with 15 K step was examined. Experimental data was modeled with existing theoretical models describing the effects of the concentration of particles on the thermal conductivity of the suspension. It was presented that thermal conductivity of MgAl_2O_4 -DG nanofluids increases proportional to volume concentration of nanoparticles.

  8. Advances in soil erosion modelling through remote sensing data availability at European scale

    NASA Astrophysics Data System (ADS)

    Panagos, Panos; Karydas, Christos; Borrelli, Pasqualle; Ballabio, Cristiano; Meusburger, Katrin

    2014-08-01

    Under the European Union's Thematic Strategy for Soil Protection, the European Commission's Directorate-General for the Environment (DG Environment) has identified the mitigation of soil losses by erosion as a priority area. Policy makers call for an overall assessment of soil erosion in their geographical area of interest. They have asked that risk areas for soil erosion be mapped under present land use and climate conditions, and that appropriate measures be taken to control erosion within the legal and social context of natural resource management. Remote sensing data help to better assessment of factors that control erosion, such as vegetation coverage, slope length and slope angle. In this context, the data availability of remote sensing data during the past decade facilitates the more precise estimation of soil erosion risk. Following the principles of the Universal Soil Loss Equation (USLE), various options to calculate vegetative cover management (C-factor) have been investigated. The use of the CORINE Land Cover dataset in combination with lookup table values taken from the literature is presented as an option that has the advantage of a coherent input dataset but with the drawback of static input. Recent developments in the Copernicus programme have made detailed datasets available on land cover, leaf area index and base soil characteristics. These dynamic datasets allow for seasonal estimates of vegetation coverage, and their application in the G2 soil erosion model which represents a recent approach to the seasonal monitoring of soil erosion. The use of phenological datasets and the LUCAS land use/cover survey are proposed as auxiliary information in the selection of the best methodology.

  9. The OH rotational population and photodissociation of H{sub 2}O in DG Tauri

    SciTech Connect

    Carr, John S.; Najita, Joan R.

    2014-06-10

    We analyze the OH rotational emission in the Spitzer Space Telescope mid-infrared spectrum of the T Tauri star DG Tau. OH is observed in emission from upper level energies of 1900 K to 28,000 K. The rotational diagram cannot be fit with any single combination of temperature and column density and has slopes that correspond to excitation temperatures ranging from 200 K to 6000 K. The relative Λ-doublet population within each rotational level is not equal, showing that the OH population is not in thermal equilibrium. The symmetric Λ-doublet state is preferred in all rotational states, with an average of 0.5 for the population ratio of the anti-symmetric to symmetric state. We show that the population distribution of the high rotational lines and the Λ-doublet ratio are consistent with the formation of OH following the photo-dissociation of H{sub 2}O by FUV photons in the second absorption band of water (∼1150-1400 Å), which includes Lyα. Other processes, OH formation from either photo-dissociation of water in the first absorption band (1450-1900 Å) or the reaction O({sup 1} D) + H{sub 2}, or collisional excitation, cannot explain the observed emission in the high rotational states but could potentially contribute to the population of lower rotational levels. These results demonstrate that the photodissociation of water is active in DG Tau and support the idea that the hot rotational OH emission commonly observed in Classical T Tauri stars is due to the dissociation of H{sub 2}O by FUV radiation.

  10. DG TO FT - AUTOMATIC TRANSLATION OF DIGRAPH TO FAULT TREE MODELS

    NASA Technical Reports Server (NTRS)

    Iverson, D. L.

    1994-01-01

    Fault tree and digraph models are frequently used for system failure analysis. Both types of models represent a failure space view of the system using AND and OR nodes in a directed graph structure. Each model has its advantages. While digraphs can be derived in a fairly straightforward manner from system schematics and knowledge about component failure modes and system design, fault tree structure allows for fast processing using efficient techniques developed for tree data structures. The similarities between digraphs and fault trees permits the information encoded in the digraph to be translated into a logically equivalent fault tree. The DG TO FT translation tool will automatically translate digraph models, including those with loops or cycles, into fault tree models that have the same minimum cut set solutions as the input digraph. This tool could be useful, for example, if some parts of a system have been modeled using digraphs and others using fault trees. The digraphs could be translated and incorporated into the fault trees, allowing them to be analyzed using a number of powerful fault tree processing codes, such as cut set and quantitative solution codes. A cut set for a given node is a group of failure events that will cause the failure of the node. A minimum cut set for a node is any cut set that, if any of the failures in the set were to be removed, the occurrence of the other failures in the set will not cause the failure of the event represented by the node. Cut sets calculations can be used to find dependencies, weak links, and vital system components whose failures would cause serious systems failure. The DG TO FT translation system reads in a digraph with each node listed as a separate object in the input file. The user specifies a terminal node for the digraph that will be used as the top node of the resulting fault tree. A fault tree basic event node representing the failure of that digraph node is created and becomes a child of the terminal

  11. Commission 10: Solar Activity

    NASA Astrophysics Data System (ADS)

    van Driel-Gesztelyi, Lidia; Schrijver, Carolus J.; Klimchuk, James A.; Charbonneau, Paul; Fletcher, Lyndsay; Hasan, S. Sirajul; Hudson, Hugh S.; Kusano, Kanya; Mandrini, Cristina H.; Peter, Hardi; Vršnak, Bojan; Yan, Yihua

    2012-04-01

    Commission 10 of the International Astronomical Union has more than 650 members who study a wide range of activity phenomena produced by our nearest star, the Sun. Solar activity is intrinsically related to solar magnetic fields and encompasses events from the smallest energy releases (nano- or even picoflares) to the largest eruptions in the Solar System, coronal mass ejections (CMEs), which propagate into the Heliosphere reaching the Earth and beyond. Solar activity is manifested in the appearance of sunspot groups or active regions, which are the principal sources of activity phenomena from the emergence of their magnetic flux through their dispersion and decay. The period 2008-2009 saw an unanticipated extended solar cycle minimum and unprecedentedly weak polar-cap and heliospheric field. Associated with that was the 2009 historical maximum in galactic cosmic rays flux since measurements begun in the middle of the 20th Century. Since then Cycle 24 has re-started solar activity producing some spectacular eruptions observed with a fleet of spacecraft and ground-based facilities. In the last triennium major advances in our knowledge and understanding of solar activity were due to continuing success of space missions as SOHO, Hinode, RHESSI and the twin STEREO spacecraft, further enriched by the breathtaking images of the solar atmosphere produced by the Solar Dynamic Observatory (SDO) launched on 11 February 2010 in the framework of NASA's Living with a Star program. In August 2012, at the time of the IAU General Assembly in Beijing when the mandate of this Commission ends, we will be in the unique position to have for the first time a full 3-D view of the Sun and solar activity phenomena provided by the twin STEREO missions about 120 degrees behind and ahead of Earth and other spacecraft around the Earth and ground-based observatories. These new observational insights are continuously posing new questions, inspiring and advancing theoretical analysis and

  12. Commission 45: Spectral Classification

    NASA Astrophysics Data System (ADS)

    Giridhar, Sunetra; Gray, Richard O.; Corbally, Christopher J.; Bailer-Jones, Coryn A. L.; Eyer, Laurent; Irwin, Michael J.; Kirkpatrick, J. Davy; Majewski, Steven; Minniti, Dante; Nordström, Birgitta

    This report gives an update of developments (since the last General Assembly at Prague) in the areas that are of relevance to the commission. In addition to numerous papers, a new monograph entitled Stellar Spectral Classification with Richard Gray and Chris Corbally as leading authors will be published by Princeton University Press as part of their Princeton Series in Astrophysics in April 2009. This book is an up-to-date and encyclopedic review of stellar spectral classification across the H-R diagram, including the traditional MK system in the blue-violet, recent extensions into the ultraviolet and infrared, the newly defined L-type and T-type spectral classes, as well as spectral classification of carbon stars, S-type stars, white dwarfs, novae, supernovae and Wolf-Rayet stars.

  13. Developing a Method for Operative Diagnostics and Appraisal of Working Capacity of a Combustion Chamber DG-90

    NASA Astrophysics Data System (ADS)

    Razboinikov, A. A.; Vashchilin, V. V.

    2016-10-01

    In the paper the problematics of gas transport system, main factors of an urgency of the development are described. Stages of a proposed reconstruction of combustion chamber DG-90 are introduced. Basic elements of the elaborated method for appraisal of risks of an emergency situation occurrence are given. The expected efficiency from implementation of the produced method is described.

  14. ZipperCream-CG and WhiteAcre-DG: Two Newly-released, Cream-type Southernpea Cultivars

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Efforts to incorporate genes conditioning a persistent green seed phenotype into Zipper Cream and White Acre type backgrounds were completed with the official release of the new southernpea cultivars ZipperCream-CG and WhiteAcre-DG on 29 January 2008. ZipperCream-CG is a high yielding, large-seeded...

  15. Q3DG: A computer program for strain-energy-release rates for delamination growth in composite laminates

    NASA Technical Reports Server (NTRS)

    Raju, I. S.

    1986-01-01

    The Q3DG is a computer program developed to perform a quasi-three-dimensional stress analysis for composite laminates which may contain delaminations. The laminates may be subjected to mechanical, thermal, and hygroscopic loads. The program uses the finite element method and models the laminates with eight-noded parabolic isoparametric elements. The program computes the strain-energy-release components and the total strain-energy release in all three modes for delamination growth. A rectangular mesh and data file generator, DATGEN, is included. The DATGEN program can be executed interactively and is user friendly. The documentation includes sections dealing with the Q3D analysis theory, derivation of element stiffness matrices and consistent load vectors for the parabolic element. Several sample problems with the input for Q3DG and output from the program are included. The capabilities of the DATGEN program are illustrated with examples of interactive sessions. A microfiche of all the examples is included. The Q3DG and DATGEN programs have been implemented on CYBER 170 class computers. Q3DG and DATGEN were developed at the Langley Research Center during the early eighties and documented in 1984 to 1985.

  16. DG TO FT - AUTOMATIC TRANSLATION OF DIGRAPH TO FAULT TREE MODELS

    NASA Technical Reports Server (NTRS)

    Iverson, D. L.

    1994-01-01

    Fault tree and digraph models are frequently used for system failure analysis. Both types of models represent a failure space view of the system using AND and OR nodes in a directed graph structure. Each model has its advantages. While digraphs can be derived in a fairly straightforward manner from system schematics and knowledge about component failure modes and system design, fault tree structure allows for fast processing using efficient techniques developed for tree data structures. The similarities between digraphs and fault trees permits the information encoded in the digraph to be translated into a logically equivalent fault tree. The DG TO FT translation tool will automatically translate digraph models, including those with loops or cycles, into fault tree models that have the same minimum cut set solutions as the input digraph. This tool could be useful, for example, if some parts of a system have been modeled using digraphs and others using fault trees. The digraphs could be translated and incorporated into the fault trees, allowing them to be analyzed using a number of powerful fault tree processing codes, such as cut set and quantitative solution codes. A cut set for a given node is a group of failure events that will cause the failure of the node. A minimum cut set for a node is any cut set that, if any of the failures in the set were to be removed, the occurrence of the other failures in the set will not cause the failure of the event represented by the node. Cut sets calculations can be used to find dependencies, weak links, and vital system components whose failures would cause serious systems failure. The DG TO FT translation system reads in a digraph with each node listed as a separate object in the input file. The user specifies a terminal node for the digraph that will be used as the top node of the resulting fault tree. A fault tree basic event node representing the failure of that digraph node is created and becomes a child of the terminal

  17. Mean Glandular dose coefficients (DgN) for x-ray spectra used in contemporary breast imaging systems

    PubMed Central

    Nosratieh, Anita; Hernandez, Andrew; Shen, Sam Z.; Yaffe, Martin J.; Seibert, J. Anthony; Boone, John M.

    2015-01-01

    Purpose To develop tables of normalized glandular dose coefficients DgN for a range of anode–filter combinations and tube voltages used in contemporary breast imaging systems. Methods Previously published mono-energetic DgN values were used with various spectra to mathematically compute DgN coefficients. The tungsten anode spectra from TASMICS were used; Molybdenum and Rhodium anode-spectra were generated using MCNPx Monte Carlo code. The spectra were filtered with various thicknesses of Al, Rh, Mo or Cu. An initial HVL calculation was made using the anode and filter material. A range of the HVL values was produced with the addition of small thicknesses of polymethyl methacrylate (PMMA) as a surrogate for the breast compression paddle, to produce a range of HVL values at each tube voltage. Using a spectral weighting method, DgN coefficients for the generated spectra were calculated for breast glandular densities of 0%, 12.5%, 25%, 37.5%, 50% and 100% for a range of compressed breast thicknesses from 3 to 8 cm. Results Eleven tables of normalized glandular dose (DgN) coefficients were produced for the following anode/filter combinations: W + 50 μm Ag, W + 500 μm Al, W + 700 μm Al, W + 200 μm Cu, W + 300 μm Cu, W + 50 μm Rh, Mo + 400 μm Cu, Mo + 30 μm Mo, Mo + 25 μm Rh, Rh + 400 μm Cu and Rh + 25 μm Rh. Where possible, these results were compared to previously published DgN values and were found to be on average less than 2% different than previously reported values. Conclusion Over 200-pages of DgN coefficients were computed for modeled x-ray system spectra that are used in a number of new breast imaging applications. The reported values were found to be in excellent agreement when compared to published values. PMID:26348995

  18. Model Commissioning Plan and Guide Specifications

    SciTech Connect

    1997-03-01

    The objectives of Model Commissioning Plan and Guide Specifications are to ensure that the design team applies commissioning concepts to the design and prepares commissioning specifications and a commission plan for inclusion in the bid construction documents.

  19. Commissioning of NSLS-II

    SciTech Connect

    Willeke, F.

    2015-05-03

    NSLS-II, the new 3rd generation light source at BNL was designed for a brightness of 1022 photons s-1mm-2mrad-2 (0.1%BW)-1. It was constructed between 2009 and 2014. The storage ring was commissioned in April 2014 which was followed by insertion device and beamline commissioning in the fall of 2014. All ambitious design parameters of the facility have already been achieved except for commissioning the full beam intensity of 500mA which requires more RF installation. This paper reports on the results of commissioning.

  20. LIGO Detector Commissioning

    NASA Astrophysics Data System (ADS)

    Raab, Frederick

    2003-04-01

    The initial LIGO interferometer design was based on more than 20 years of experience with test interferometers, but the increase in scale, new operating environments and extreme technical requirements presented challenges for commissioning. Detector installation began in 1998 with injection optics at Hanford, WA. By 1999, light was resonating in a single 2-km Fabry-Perot arm cavity. Subsequent engineering runs tested stability and analyzed environmental influences, particularly the earth tides and the microseism. By October 2000, the first lock of a kilometer-scale, power recycled Fabry-Perot-Michelson interferometer was obtained, using an automated system to analyze optical signals and reconfigure control loops as the mirrors are drawn into position. The many control loops that minimize length and angle fluctuations of the mirrors relative to the laser light were tuned and noise sources were identified and reduced iteratively as sensitivity improved by several orders of magnitude. Following installation of the last LIGO mirror in 2001, engineering run 7 provided the first triple-coincidence operation of LIGO's interferometers at Hanford and Livingston, LA in early 2002. Clear signals of mirrors recoiling from the Brownian motion of the suspension-wire violin modes first emerged from the noise during science run 1 in September 2002, at approximately the expected amplitude. Detector robustness has steadily improved and uninterrupted locking on a dark fringe for more than a day has been achieved. The support of the US National Science Foundation under Cooperative Agreement No. PHY-0107417 is gratefully acknowledged.

  1. National Knowledge Commission

    NASA Astrophysics Data System (ADS)

    Pitroda, Sam

    2007-04-01

    India's National Knowledge Commission (NKC) established by the prime minister is focused on building institutions and infrastructure in Education, Science and Technology, Innovation etc. to meet the challenges of the knowledge economy in the 21st century and increase India's competitive advantage in the global market. India today stands poised to reap the benefits of a rapidly growing economy and a major demographic advantage, with 550 million young people below the age of 25 years, the largest in the world. The NKC is focused on five critical areas of knowledge related to access, concepts, creation, applications and services. This includes a variety of subject areas such as language, translations, libraries, networks, portals, affirmative action, distance learning, intellectual property, Entrepreneurship, application in Agriculture, health, small and medium scale industries, e-governance etc. One of the keys to this effort is to build a national broadband gigabit of networks of 500 nodes to connect universities, Libraries, Laboratories, Hospitals, Agriculture institutions etc. to share resources and collaborate on multidisciplinary activities. This presentation will introduce the NKC, discuss methodology, subject areas, specific recommendation and outline a plan to build knowledge networks and specifics on network architecture, applications, and utilities.

  2. Commissioning the SNO+ detector

    NASA Astrophysics Data System (ADS)

    Descamps, Freija; SNO+ Collaboration

    2016-09-01

    The SNO+ experiment is the successor to the Sudbury Neutrino Observatory (SNO), in which SNO's heavy water is replaced by approximately 780T of liquid scintillator (LAB). The combination of the 2km underground location, the use of ultra-clean materials and the high light-yield of the liquid scintillator means that a low background level and a low energy threshold can be achieved. This creates a new multipurpose neutrino detector with the potential to address a diverse set of physics goals, including the detection of reactor, solar, geo- and supernova neutrinos. A main physics goal of SNO+ is the search for neutrinoless double beta decay. By loading the liquid scintillator with 0.5% of natural Tellurium, resulting in about 1300kg of 130Te (isotopic abundance is slightly over 34%), a competitive sensitivity to the effective neutrino mass can be reached. This talk will present the status of the SNO+ detector, specifically the results and status of the detector commissioning with water.

  3. Twentieth anniversary of the European Union health mandate: taking stock of perceived achievements, failures and missed opportunities – a qualitative study

    PubMed Central

    2013-01-01

    Background The European Union (EU) health mandate was initially defined in the Maastricht Treaty in 1992. The twentieth anniversary of the Treaty offers a unique opportunity to take stock of EU health actions by giving an overview of influential public health related EU-level policy outputs and a summary of policy outputs or actions perceived as an achievement, a failure or a missed opportunity. Methods Semi-structured expert interviews (N = 20) were conducted focusing on EU-level actions that were relevant for health. Respondents were asked to name EU policies or actions that they perceived as an achievement, a failure or a missed opportunity. A directed content analysis approach was used to identify expert perceptions on achievements, failures and missed opportunities in the interviews. Additionally, a nominal group technique was applied to identify influential and public health relevant EU-level policy outputs. Results The ranking of influential policy outputs resulted in top positions of adjudications and legislations, agencies, European Commission (EC) programmes and strategies, official networks, cooperative structures and exchange efforts, the work on health determinants and uptake of scientific knowledge. The assessment of EU health policies as being an achievement, a failure or a missed opportunity was often characterized by diverging respondent views. Recurring topics that emerged were the Directorate General for Health and Consumers (DG SANCO), EU agencies, life style factors, internal market provisions as well as the EU Directive on patients’ rights in cross-border healthcare. Among these recurring topics, expert perceptions on the establishment of DG SANCO, EU public health agencies, and successes in tobacco control were dominated by aspects of achievements. The implementation status of the Health in All Policy approach was perceived as a missed opportunity. Conclusions When comparing the emerging themes from the interviews conducted with the

  4. Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893.

    PubMed

    Romano, Ariel; Trimble, Lyndsay; Hobusch, Ashtian R; Schroeder, Kristine J; Amin, Shady A; Hartnett, Andrej D; Barker, Ryan A; Crumbliss, Alvin L; Carrano, Carl J

    2013-08-01

    While there has been extensive interest in the use of boron isotope ratios as a surrogate of pH in paleoclimate studies in the context of climate change-related questions, the high (0.4 mM) concentration and the depth-independent (conservative or non-nutrient-like) concentration profile of this element have led to boron being neglected as a potentially biologically relevant element in the modern ocean. Here we report that boron affects the expression of a number of protein and genes in the "algal-associated" Gram-negative marine bacterium Marinobacter algicola DG893. Most intriguingly, a number of these proteins and genes are related to iron uptake. In a recent separate publication we have shown that boron regulates one such iron transport related protein, i.e. the periplasmic iron binding protein FbpA via a direct interaction of the metalloid with this protein. Here we show that a number of other iron uptake related genes are also affected by boron but in the opposite way i.e. they are up-regulated. We propose that the differential effect of boron on FbpA expression relative to other iron transport related genes is a result of an interaction between boron and the global iron regulatory protein Fur.

  5. Effects of hexagonal boron nitride on dry compression mixture of Avicel DG and Starch 1500.

    PubMed

    Uğurlu, Timuçin; Halaçoğlu, Mekin Doğa

    2016-01-01

    The objective of this study was to investigate the lubrication properties of hexagonal boron nitride (HBN) on a (1:1) binary mixture of Avicel DG and Starch 1500 after using the dry granulation-slugging method and compare it with conventional lubricants, such as magnesium stearate (MGST), glyceryl behenate (COMP) and stearic acid (STAC). MGST is one of the most commonly used lubricants in the pharmaceutical industry. However, it has several adverse effects on tablet properties. In our current study, we employed various methods to eradicate the work hardening phenomenon in dry granulation, and used HBN as a new lubricant to overcome the adverse effects of other lubricants on tablet properties. HBN was found to be as effective as MGST and did not show any significant adverse effects on the crushing strength or work hardening. From the scanning electron microscope (SEM) images, it was concluded that HBN distributed better than MGST. As well as showing better distribution, HBN's effect on disintegration was the least pronounced. Semi-quantitative weight percent distribution of B and N elements in the tablets was obtained using EDS (energy dispersive spectroscopy). Based on atomic force microscope (AFM) surface roughness images, formulations prepared with 1% HBN showed better plastic character than those prepared with MGST.

  6. Analysis of high-k spacer on symmetric underlap DG-MOSFET with Gate Stack architecture

    NASA Astrophysics Data System (ADS)

    Das, Rahul; Chakraborty, Shramana; Dasgupta, Arpan; Dutta, Arka; Kundu, Atanu; Sarkar, Chandan K.

    2016-09-01

    This paper shows the systematic study of underlap double gate (U-DG) NMOSFETs with Gate Stack (GS) under the influence of high-k spacers. In highly scaled devices, underlap is used at the Source and Drain side so as to reduce the short channel effects (SCE's), however, it significantly reduces the on current due to the increased channel resistance. To overcome these drawbacks, the use of high-k spacers is projected as one of the remedies. In this paper, the analog performance of the devices is studied on the basis of parameters like transconductance (gm), transconductance generation factor (gm/Id) and intrinsic gain (gmro). The RF performance is analyzed on the merits of intrinsic capacitance (Cgd, Cgs), resistance (Rgd, Rgs), transport delay (τm), inductance (Lsd), cutoff frequency (fT), and the maximum frequency of oscillation (fmax). The circuit performance of the devices are studied by implementing the device as the driver MOSFET in a Single Stage Common Source Amplifier. The Gain Bandwidth Product (GBW) has been analyzed from the frequency response of the circuit.

  7. Results and limits in the 1-D analytical modeling for the asymmetric DG SOI MOSFET

    NASA Astrophysics Data System (ADS)

    Cobianu, O.; Glesner, M.

    2008-05-01

    This paper presents the results and the limits of 1-D analytical modeling of electrostatic potential in the low-doped p type silicon body of the asymmetric n-channel DG SOI MOSFET, where the contribution to the asymmetry comes only from p- and n-type doping of polysilicon used as the gate electrodes. Solving Poisson's equation with boundary conditions based on the continuity of normal electrical displacement at interfaces and the presence of a minimum electrostatic potential by using the Matlab code we have obtained a minimum potential with a slow variation in the central zone of silicon with the value pinned around 0.46 V, where the applied VGS voltage varies from 0.45 V to 0.95 V. The paper states clearly the validity domain of the analytical solution and the important effect of the localization of the minimum electrostatic potential value on the potential variation at interfaces as a function of the applied VGS voltage.

  8. Reflections on the Gordon Commission

    ERIC Educational Resources Information Center

    Haertel, Edward

    2014-01-01

    Background:This brief reflection on the work of the Gordon Commission calls out significant themes and implications found in the various papers authored by the commissioners and other scholars, especially those included in this special issue of Teachers College Record. Purpose: The forward-looking vision of the Gordon Commission is contrasted with…

  9. Vermont Technical Education Commission Report.

    ERIC Educational Resources Information Center

    Vermont State Technical Education Commission, Montpelier.

    A 1968 New England Regional Commission grant to the Vermont Department of Administration financed a feasibility study for a technical college at the postsecondary level. The commission undertook two specific studies: an examination of ultimate career destinations of Vermont secondary students and a survey of Vermont industry to determine immediate…

  10. Photonics21 and the perspectives from the European photonics industry

    NASA Astrophysics Data System (ADS)

    Mertin, Michael

    2014-03-01

    Photonics provide indispensable technology buildings bricks that enable a wide range of products as well as driving the development of entirely new industries. The European Commission recognized the potential of photonics to strengthen Europe's industrial and innovation capacity and consequently declared photonics as a Key Enabling Technology. Photonics21 as partner of the European Commission developed a Multiannual Strategic Roadmap which aims at boosting European photonics along the whole innovation chain with special focus on the gap between generating knowledge and products. The roadmap will be realized in a Public Private Partnership between the European photonics industry and the European Commission until 2020. In this PPP it is intended that the industry commits to leverage the public funds by the factor of 4.

  11. Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Matsakis, Demetrios; Defraigne, Pascale; Hosokawa, M.; Leschiutta, S.; Petit, G.; Zhai, Z.-C.

    2007-03-01

    The most intensely discussed and controversial issue in time keeping has been the proposal before the International Telecommunications Union (ITU) to redefine Coordinated Universal Time (UTC) so as to replace leap seconds by leap hours. Should this proposal be adopted, the practice of inserting leap seconds would cease after a specific date. Should the Earth's rotation continue to de-accelerate at its historical rate, the next discontinuity in UTC would be an hour inserted several centuries from now. Advocates of this proposal cite the need to synchronize satellite and other systems, such as GPS, Galileo, and GLONASS, which did not exist and were not envisioned when the current system was adopted. They note that leap second insertions can be and have been incorrectly implemented or accounted for. Such errors have to date had localized impact, but they could cause serious mishaps involving loss of life. For example, some GPS receivers have been known to fail simply because there was no leap second after a long enough interval, other GPS receivers failed because the leap second information was broadcast more than three months in advance, and some commercial software used for internet time-transfer Network Time Protocol (NTP) could either discard all data received after a leap second or interpret it as a frequency change. The ambiguity associated with the extra second could also disrupt financial accounting and certain forms of encryption. Those opposed to the proposal question the need for a change, and also point out the costs of adjusting to the proposed change and its inconvenience to amateur astronomers and others who rely upon astronomical calculations published in advance. Reports have been circulated that the cost of checking and correcting software to accommodate the new definition of UTC would be many millions of dollars for some systems. In October 2005 American Astronomical Society asked the ITU for a year's time to study the issue. This commission has

  12. Nanoscale T-shaped Double Gate DG MOSFET: Numerical Investigation for Analog/RF and Digital Performance

    NASA Astrophysics Data System (ADS)

    Kumari, Vandana; Ilango, Aravindan; Saxena, Manoj; Gupta, Mridula

    2016-01-01

    The present work demonstrates the investigation of T-shaped Double Gate MOSFET for analog and digital performance. The 2D analytical modeling scheme is presented using Evanescent Mode Analysis (EMA). The applicability of the proposed model has been verified using ATLAS 3D device simulation. The device exploits peaks in the electric field inside the channel (due to T-shaped gate) for better carrier transport efficiency and subsequently higher drain current and trans-conductance. The impact of dielectric constant of the void layer (due to T-shaped gate) on the electrostatic of the device has been investigated using basic electrical parameters such as: sub-threshold slope, Drain Induced Barrier Lowering DIBL, device gain and Ion/Ioff ratio. The comparative study between T-shaped DG with the conventional DG MOSFET is also presented.

  13. Fenpropathrin biodegradation pathway in Bacillus sp. DG-02 and its potential for bioremediation of pyrethroid-contaminated soils.

    PubMed

    Chen, Shaohua; Chang, Changqing; Deng, Yinyue; An, Shuwen; Dong, Yi Hu; Zhou, Jianuan; Hu, Meiying; Zhong, Guohua; Zhang, Lian-Hui

    2014-03-12

    The widely used insecticide fenpropathrin in agriculture has become a public concern because of its heavy environmental contamination and toxic effects on mammals, yet little is known about the kinetic and metabolic behaviors of this pesticide. This study reports the degradation kinetics and metabolic pathway of fenpropathrin in Bacillus sp. DG-02, previously isolated from the pyrethroid-manufacturing wastewater treatment system. Up to 93.3% of 50 mg L(-1) fenpropathrin was degraded by Bacillus sp. DG-02 within 72 h, and the degradation rate parameters qmax, Ks, and Ki were determined to be 0.05 h(-1), 9.0 mg L(-1), and 694.8 mg L(-1), respectively. Analysis of the degradation products by gas chromatography-mass spectrometry led to identification of seven metabolites of fenpropathrin, which suggest that fenpropathrin could be degraded first by cleavage of its carboxylester linkage and diaryl bond, followed by degradation of the aromatic ring and subsequent metabolism. In addition to degradation of fenpropathrin, this strain was also found to be capable of degrading a wide range of synthetic pyrethroids including deltamethrin, λ-cyhalothrin, β-cypermethrin, β-cyfluthrin, bifenthrin, and permethrin, which are also widely used insecticides with environmental contamination problems with the degradation process following the first-order kinetic model. Bioaugmentation of fenpropathrin-contaminated soils with strain DG-02 significantly enhanced the disappearance rate of fenpropathrin, and its half-life was sharply reduced in the soils. Taken together, these results depict the biodegradation mechanisms of fenpropathrin and also highlight the promising potentials of Bacillus sp. DG-02 in bioremediation of pyrethroid-contaminated soils.

  14. The [Ne III] Jet of DG Tau and its Ionization Scenarios

    NASA Astrophysics Data System (ADS)

    Liu, Chun-Fan; Shang, Hsien; Herczeg, Gregory J.; Walter, Frederick M.

    2016-12-01

    Forbidden neon emission from jets of low-mass young stars can be used to probe the underlying high-energy processes in these systems. We analyze spectra of the jet of DG Tau obtained with the Very Large Telescope/X-Shooter spectrograph in 2010. [Ne iii] λ 3869 is clearly detected in the innermost 3″ microjet and the outer knot located at ˜ 6\\buildrel{\\prime\\prime}\\over{.} 5. The velocity structure of the inner microjet can be decomposed into the low-velocity component at ˜ -70 km s-1 and the high-velocity component (HVC) at ˜ -180 km s-1. Based on the observed [Ne iii] flux and its spatial extent, we suggest the origins of the [Ne iii] emission regions and their relation with known X-ray sources along the jet. The flares from the hard X-ray source close to the star may be the main ionization source of the innermost microjet. The fainter soft X-ray source at 0\\buildrel{\\prime\\prime}\\over{.} 2 from the star may provide sufficient heating to help to sustain the ionization fraction against recombination in the flow. The outer knot may be reionized by shocks faster than 100 km s-1 such that [Ne iii] emission reappears and the soft X-ray emission at 5\\buildrel{\\prime\\prime}\\over{.} 5 is produced. Velocity decomposition of the archival Hubble Space Telescope spectra obtained in 1999 shows that the HVC had been faster, with a velocity centroid of ˜ -260 km s-1. Such a decrease in velocity may potentially be explained by the expansion of the stellar magnetosphere, changing the truncation radius and thus the launching speed of the jet. The energy released by magnetic reconnections during relaxation of the transition can heat the gas up to several tens of megakelvin and provide the explanation for on-source keV X-ray flares that ionize the neon microjet.

  15. TENTATIVE EVIDENCE FOR RELATIVISTIC ELECTRONS GENERATED BY THE JET OF THE YOUNG SUN-LIKE STAR DG Tau

    SciTech Connect

    Ainsworth, Rachael E.; Ray, Tom P.; Taylor, Andrew M.; Scaife, Anna M. M.; Green, David A.; Buckle, Jane V.

    2014-09-01

    Synchrotron emission has recently been detected in the jet of a massive protostar, providing further evidence that certain jet formation characteristics for young stars are similar to those found for highly relativistic jets from active galactic nuclei. We present data at 325 and 610 MHz taken with the Giant Metrewave Radio Telescope of the young, low-mass star DG Tau, an analog of the Sun soon after its birth. This is the first investigation of a low-mass young stellar object at such low frequencies. We detect emission with a synchrotron spectral index in the proximity of the DG Tau jet and interpret this emission as a prominent bow shock associated with this outflow. This result provides tentative evidence for the acceleration of particles to relativistic energies due to the shock impact of this otherwise very low-power jet against the ambient medium. We calculate the equipartition magnetic field strength B {sub min} ≈ 0.11 mG and particle energy E {sub min} ≈ 4 × 10{sup 40} erg, which are the minimum requirements to account for the synchrotron emission of the DG Tau bow shock. These results suggest the possibility of low energy cosmic rays being generated by young Sun-like stars.

  16. KINEMATICS OF THE OUTFLOW FROM THE YOUNG STAR DG TAU B: ROTATION IN THE VICINITIES OF AN OPTICAL JET

    SciTech Connect

    Zapata, Luis A.; Lizano, Susana; Rodríguez, Luis F.; Loinard, Laurent; Tafoya, Daniel; Ho, Paul T. P.; Fernández-López, Manuel

    2015-01-10

    We present {sup 12}CO(2-1) line and 1300 μm continuum observations made with the Submillimeter Array of the young star DG Tau B. We find, in the continuum observations, emission arising from the circumstellar disk surrounding DG Tau B. The {sup 12}CO(2-1) line observations, on the other hand, revealed emission associated with the disk and the asymmetric outflow related with this source. Velocity asymmetries about the flow axis are found over the entire length of the flow. The amplitude of the velocity differences is of the order of 1-2 km s{sup –1} over distances of about 300-400 AU. We interpret them as a result of outflow rotation. The sense of the outflow and disk rotation is the same. Infalling gas from a rotating molecular core cannot explain the observed velocity gradient within the flow. Magneto-centrifugal disk winds or photoevaporated disk winds can produce the observed rotational speeds if they are ejected from a Keplerian disk at radii of several tens of AU. Nevertheless, these slow winds ejected from large radii are not very massive, and cannot account for the observed linear momentum and angular momentum rates of the molecular flow. Thus, the observed flow is probably entrained material from the parent cloud. DG Tau B is a good laboratory to model in detail the entrainment process and see if it can account for the observed angular momentum.

  17. Influence of Underlap on Gate Stack DG-MOSFET for analytical study of Analog/RF performance

    NASA Astrophysics Data System (ADS)

    Kundu, Atanu; Dasgupta, Arpan; Das, Rahul; Chakraborty, Shramana; Dutta, Arka; Sarkar, Chandan K.

    2016-06-01

    In this paper, the characteristics of 18 nm Underlap Double Gate (U-DG) NMOSFET with gate stack, (GS) are presented. The high-k dielectric as gate insulator under consideration is Hafnium Dioxide (HfO2). The SiO2 padding reduces the effect of scattering at the silicon and oxide interface. The ratio of on current to off current is used for optimizing the underlap length. The Analog and RF performance comparison are shown in this paper considering the drain current (Id), the transconductance (gm), the intrinsic gain (gmRo), the intrinsic capacitances (Cgs, Cgd), the intrinsic resistances (Rgs, Rgd), the transport delay (τm), the intrinsic inductance (Hsd), the unity current gain cut-off frequency (fT) and the maximum frequency of oscillation (fmax). RF parameters are extracted using the Non Quasi Static (NQS) model of the U-DG MOSFET. The performance of single stage amplifiers using the devices is also analyzed. The sharpest transition is shown in case of U-DG-GS MOSFET with optimized underlap length and enhancement in the intrinsic capacitances and resistances, and unity Gain Bandwidth product in case of devices with GS.

  18. A Simultaneous Biogeography based Optimal Placement of DG Units and Capacitor Banks in Distribution Systems with Nonlinear Loads

    NASA Astrophysics Data System (ADS)

    Sadeghi, Hassan; Ghaffarzadeh, Navid

    2016-09-01

    This paper uses a new algorithm namely biogeography based optimization (BBO) intended for the simultaneous placement of the distributed generation (DG) units and the capacitor banks in the distribution network. The procedure of optimization has been conducted in the presence of nonlinear loads (a cause of harmonic injection). The purpose of simultaneous optimal placement of the DG and the capacitor is the reduction of active and reactive losses. The difference in the values of loss reduction at different levels of the load have been included in the objective function and the considered objective function includes the constraints of voltage, size and the number of DG units and capacitor banks and the allowable range of the total harmonic distortion (THD) of the total voltage in accordance with the IEEE 519 standards. In this paper the placement has been performed on two load types ie constant and mixed power, moreover the effects of load models on the results and the effects of optimal placement on reduction of the THD levels have also been analyzed. The mentioned cases have been studied on a 33 bus radial distribution system.

  19. Urinary C3dg and C5b-9 indicate active immune disease in human membranous nephropathy.

    PubMed

    Brenchley, P E; Coupes, B; Short, C D; O'Donoghue, D J; Ballardie, F W; Mallick, N P

    1992-04-01

    We have measured complement activation markers, C3dg and C5b-9 in plasma and urine from patients with idiopathic membranous nephropathy and IgA nephropathy. There was no significant difference in levels of plasma C5b-9 between the patient groups. However, high plasma concentrations of C3dg were associated significantly with IgA nephropathy with 45% of patients having levels over 25 U/ml (P less than 0.001). High concentrations of urinary C3dg and C5b-9 were associated significantly with membranous nephropathy (43% and 43% of the patient group, respectively) compared to patients with IgA nephropathy (10% and 0%, respectively, P less than 0.001). In a retrospective analysis of 31 patients with membranous nephropathy, 66% of patients with high initial urinary C5b-9 showed an unstable clinical course compared to 18% of patients with initially absent or low C5b-9 (P less than 0.001). We suggest that high urinary C5b-9 identifies those patients with a membranous lesion which retains an active immunological component contributing to the pathology of progressive glomerular damage.

  20. DgSMC-B code: A robust and autonomous direct simulation Monte Carlo code for arbitrary geometries

    NASA Astrophysics Data System (ADS)

    Kargaran, H.; Minuchehr, A.; Zolfaghari, A.

    2016-07-01

    In this paper, we describe the structure of a new Direct Simulation Monte Carlo (DSMC) code that takes advantage of combinatorial geometry (CG) to simulate any rarefied gas flows Medias. The developed code, called DgSMC-B, has been written in FORTRAN90 language with capability of parallel processing using OpenMP framework. The DgSMC-B is capable of handling 3-dimensional (3D) geometries, which is created with first-and second-order surfaces. It performs independent particle tracking for the complex geometry without the intervention of mesh. In addition, it resolves the computational domain boundary and volume computing in border grids using hexahedral mesh. The developed code is robust and self-governing code, which does not use any separate code such as mesh generators. The results of six test cases have been presented to indicate its ability to deal with wide range of benchmark problems with sophisticated geometries such as airfoil NACA 0012. The DgSMC-B code demonstrates its performance and accuracy in a variety of problems. The results are found to be in good agreement with references and experimental data.

  1. Differential responses of tumors and normal brain to the combined treatment of 2-DG and radiation in glioablastoma.

    PubMed

    Prasanna, Venkatesh K; Venkataramana, Neelam K; Dwarakanath, B S; Santhosh, Vani

    2009-09-01

    2-Deoxy-D-glucose (2-DG), an inhibitor of glucose transport and glycolysis, enhances radiation damage selectively in tumor cells by modulating damage response pathways resulting in cell death in vitro and local tumor control. Phase I and II clinical trials in patients with malignant glioma have shown excellent tolerance to a combined treatment of orally administered 2-DG and hypofractionated radiotherapy without any acute toxicity and late radiation damage. Phase III efficacy trials are currently at an advanced stage. Re-exploratory surgery performed in 13 patients due to persistent symptoms of elevated ICP and mass effect at different follow-up periods revealed extensive tumor necrosis with well-preserved normal brain tissue adjoining the tumor included in the treatment volume as revealed by a histological examination. These observations are perhaps the first clinical evidences for differential effects of 2-DG on tumors and normal tissues in conformity with earlier in vitro and in vivo studies in normal and tumor-bearing mice.

  2. The Rise of the Information Society amongst European Academics

    ERIC Educational Resources Information Center

    Salajan, Florin D.

    2008-01-01

    This study investigates the information society discourse in the European Union in relation to the European Commission's eLearning programmes, based on selected academics' conceptualisation of the term. It reveals a mixed picture of the perceptions that academics have of the information society in their respective countries. The findings indicate…

  3. TELRI: Trans European Language Resources Infrastructure Newsletter, 1995-1997.

    ERIC Educational Resources Information Center

    TELRI: Trans European Language Resources Infrastructure Newsletter, 1997

    1997-01-01

    The first seven issues of the Trans European Language Resources Infrastructure (TELRI) newsletter, a publication of the COPERNICUS project funded by the Commission of the European Communities, date from September 1995 to October 1997. The first three issues contain articles in the origins of TELRI, its members, working groups, and events. TELRI's…

  4. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by...

  5. 11 CFR 9032.3 - Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Commission. 9032.3 Section 9032.3 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: PRESIDENTIAL PRIMARY MATCHING FUND DEFINITIONS § 9032.3 Commission. Commission means the Federal Election Commission, 999 E Street...

  6. 11 CFR 9002.3 - Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Commission. 9002.3 Section 9002.3 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: GENERAL ELECTION FINANCING DEFINITIONS § 9002.3 Commission. Commission means the Federal Election Commission, 999 E Street,...

  7. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false The Commission. 140.10 Section 140.10 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION ORGANIZATION, FUNCTIONS, AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of...

  8. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false The Commission. 375.101... OF ENERGY REVISED GENERAL RULES THE COMMISSION General Provisions § 375.101 The Commission. (a) Establishment. The Federal Energy Regulatory Commission is an independent regulatory commission within...

  9. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by...

  10. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by...

  11. Wisconsin SRF Electron Gun Commissioning

    SciTech Connect

    Bisognano, Joseph J.; Bissen, M.; Bosch, R.; Efremov, M.; Eisert, D.; Fisher, M.; Green, M.; Jacobs, K.; Keil, R.; Kleman, K.; Rogers, G.; Severson, M.; Yavuz, D. D.; Legg, Robert A.; Bachimanchi, Ramakrishna; Hovater, J. Curtis; Plawski, Tomasz; Powers, Thomas J.

    2013-12-01

    The University of Wisconsin has completed fabrication and commissioning of a low frequency (199.6 MHz) superconducting electron gun based on a quarter wave resonator (QWR) cavity. Its concept was optimized to be the source for a CW free electron laser facility. The gun design includes active tuning and a high temperature superconducting solenoid. We will report on the status of the Wisconsin SRF electron gun program, including commissioning experience and first beam measurements.

  12. NSF commission holds first meeting

    NASA Astrophysics Data System (ADS)

    Jones, Richard M.

    There has been considerable discussion in Washington science policy circles over the past few weeks about the newly established National Science Board Commission on the Future of the National Science Foundation. The commission, chaired by William Danforth, chancellor of Washington University, and Robert Galvin, former chief executive officer of Motorola, held its first meeting on September 17. Unfortunately, this meeting offered few indications of what changes might result from this exercise.

  13. Willingness for Mobility amongst European Fishermen

    ERIC Educational Resources Information Center

    Pita, Cristina; Dickey, Heather; Pierce, Graham J.; Mente, Elena; Theodossiou, Ioannis

    2010-01-01

    The global trend of fisheries overexploitation and collapse has resulted in the need to reduce fishing effort, and providing alternative employment for fishermen is a frequently mentioned policy option in order to achieve this goal. Reducing fishing effort is central to the European Commission Common Fisheries Policy and over the years, the…

  14. Chronic Dietary Administration of the Glycolytic Inhibitor 2-Deoxy-D-Glucose (2-DG) Inhibits the Growth of Implanted Ehrlich’s Ascites Tumor in Mice

    PubMed Central

    Singh, Saurabh; Pandey, Sanjay; Bhatt, Anant Narayan; Chaudhary, Richa; Bhuria, Vikas; Kalra, Namita; Soni, Ravi; Roy, Bal Gangadhar; Saluja, Daman; Dwarakanath, Bilikere S.

    2015-01-01

    Background Dietary energy restriction (DER) has been well established as a potent anticancer strategy. Non-adoption of restricted diet for an extended period has limited its practical implementation in humans with a compelling need to develop agents that mimic effects similar to DER, without reduction in actual dietary intake. Glycolytic inhibitor, 2-deoxy-D-glucose (2-DG), has recently been shown to possess potential as an energy restriction mimetic agent (ERMA). In the present study we evaluated the effect of dietary 2-DG administration on a mouse tumor model, with a focus on several potential mechanisms that may account for the inhibition of tumorigenesis. Methodology/Principal Findings Swiss albino strain ‘A’ mice were administered with 0.2% and 0.4% w/v 2-DG in drinking water for 3 months prior to tumor implantation (Ehrlich’s ascites carcinoma; EAC) and continued till the termination of the study with no adverse effects on general physiology and animal growth. Dietary 2-DG significantly reduced the tumor incidence, delayed the onset, and compromised the tumor growth along with enhanced survival. We observed reduced blood glucose and serum insulin levels along with decreased proliferating cell nuclear antigen (PCNA) and bromodeoxyuridine positive (BrdU+) tumor cells in 2-DG fed mice. Also, reduced levels of certain key players of metabolic pathways such as phosphatidylinositol 3-kinase (PI3K), phosphorylated-Akt and hypoxia inducible factor-1 alpha (HIF-1α) were also noted in tumors of 2-DG fed mice. Further, decrease in CD4+/CD8+ ratio and T-regulatory cells observed in 2-DG fed mice suggested enhanced antitumor immunity and T cell effector function. Conclusion/Significance These results strongly suggest that dietary 2-DG administration in mice, at doses easily achievable in humans, suitably modulates several pleotrophic factors mimicking DER and inhibits tumorigenesis, emphasizing the use of ERMAs as a promising cancer preventive strategy. PMID

  15. 76 FR 4369 - Special Law Enforcement Commissions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ... Bureau of Indian Affairs Special Law Enforcement Commissions AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice. SUMMARY: This notice announces the online publication of the Interim Special Law Enforcement Commission Policy, Rules and Procedures, the Interim Special Law Enforcement Commission...

  16. EMODNet Bathymetry - building and providing a high resolution digital bathymetry for European seas

    NASA Astrophysics Data System (ADS)

    Schaap, Dick M. A.

    2015-04-01

    Access to marine data is a key issue for the implementation of the EU Marine Strategy Framework Directive (MSFD). The EU communication 'Marine Knowledge 2020' underpins the importance of data availability and harmonising access to marine data from different sources. The European Marine Observation and Data Network (EMODnet) is a long term marine data initiative from the European Commission Directorate-General for Maritime Affairs and Fisheries (DG MARE) underpinning the Marine Knowledge 2020 strategy. EMODnet is a consortium of organisations assembling European marine data, data products and metadata from diverse sources in a uniform way. The main purpose of EMODnet is to unlock fragmented and hidden marine data resources and to make these available to individuals and organisations (public and private), and to facilitate investment in sustainable coastal and offshore activities through improved access to quality-assured, standardised and harmonised marine data which are interoperable and free of restrictions on use. The EMODnet data infrastructure is developed through a stepwise approach in three major phases. Currently EMODnet is in the 2nd phase of development with seven sub-portals in operation that provide access to marine data from the following themes: bathymetry, geology, physics, chemistry, biology, seabed habitats and human activities. EMODnet development is a dynamic process so new data, products and functionality are added regularly while portals are continuesly improved to make the service more fit for purpose and user friendly with the help of users and stakeholders. The EMODnet Bathymetry project develops and publishes Digital Terrain Models (DTM) for the European seas. These are produced from survey and aggregated data sets, that are indexed with metadata by adopting the SeaDataNet Common Data Index (CDI) data discovery and access service and the SeaDataNet Sextant data products catalogue service. The new EMODnet DTM will have a resolution of 1

  17. Quantifying Metabolic Heterogeneity in Head and Neck Tumors in Real Time: 2-DG Uptake Is Highest in Hypoxic Tumor Regions

    PubMed Central

    Nakajima, Erica C.; Laymon, Charles; Oborski, Matthew; Hou, Weizhou; Wang, Lin; Grandis, Jennifer R.; Ferris, Robert L.; Mountz, James M.; Van Houten, Bennett

    2014-01-01

    Purpose Intratumoral metabolic heterogeneity may increase the likelihood of treatment failure due to the presence of a subset of resistant tumor cells. Using a head and neck squamous cell carcinoma (HNSCC) xenograft model and a real-time fluorescence imaging approach, we tested the hypothesis that tumors are metabolically heterogeneous, and that tumor hypoxia alters patterns of glucose uptake within the tumor. Experimental Design Cal33 cells were grown as xenograft tumors (n = 16) in nude mice after identification of this cell line's metabolic response to hypoxia. Tumor uptake of fluorescent markers identifying hypoxia, glucose import, or vascularity was imaged simultaneously using fluorescent molecular tomography. The variability of intratumoral 2-deoxyglucose (IR800-2-DG) concentration was used to assess tumor metabolic heterogeneity, which was further investigated using immunohistochemistry for expression of key metabolic enzymes. HNSCC tumors in patients were assessed for intratumoral variability of 18F-fluorodeoxyglucose (18F-FDG) uptake in clinical PET scans. Results IR800-2-DG uptake in hypoxic regions of Cal33 tumors was 2.04 times higher compared to the whole tumor (p = 0.0001). IR800-2-DG uptake in tumors containing hypoxic regions was more heterogeneous as compared to tumors lacking a hypoxic signal. Immunohistochemistry staining for HIF-1α, carbonic anhydrase 9, and ATP synthase subunit 5β confirmed xenograft metabolic heterogeneity. We detected heterogeneous 18F-FDG uptake within patient HNSCC tumors, and the degree of heterogeneity varied amongst tumors. Conclusion Hypoxia is associated with increased intratumoral metabolic heterogeneity. 18F-FDG PET scans may be used to stratify patients according to the metabolic heterogeneity within their tumors, which could be an indicator of prognosis. PMID:25127378

  18. Roles of DgBRC1 in Regulation of Lateral Branching in Chrysanthemum (Dendranthema ×grandiflora cv. Jinba)

    PubMed Central

    Chen, Xiaoli; Zhou, Xiaoyang; Xi, Lin; Li, Junxiang; Zhao, Ruiyan; Ma, Nan; Zhao, Liangjun

    2013-01-01

    The diverse plasticity of plant architecture is largely determined by shoot branching. Shoot branching is an event regulated by multiple environmental, developmental and hormonal stimuli through triggering lateral bud response. After perceiving these signals, the lateral buds will respond and make a decision on whether to grow out. TCP transcriptional factors, BRC1/TB1/FC1, were previously proven to be involved in local inhibition of shoot branching in Arabidopsis, pea, tomato, maize and rice. To investigate the function of BRC1, we isolated the BRC1 homolog from chrysanthemum. There were two transcripts of DgBRC1 coming from two alleles in one locus, both of which complemented the multiple branches phenotype of Arabidopsis brc1-1, indicating that both are functionally conserved. DgBRC1 was mainly expressed in dormant axillary buds, and down-regulated at the bud activation stage, and up-regulated by higher planting densities. DgBRC1 transcripts could respond to apical auxin supply and polar auxin transport. Moreover, we found that the acropetal cytokinin stream promoted branch outgrowth whether or not apical auxin was present. Basipetal cytokinin promoted outgrowth of branches in the absence of apical auxin, while strengthening the inhibitory effects on lower buds in the presence of apical auxin. The influence of auxin and strigolactons (SLs) on the production of cytokinin was investigated, we found that auxin locally down-regulated biosynthesis of cytokinin in nodes, SLs also down-regulated the biosynthesis of cytokinin, the interactions among these phytohormones need further investigation. PMID:23613914

  19. The Politics of the Economics of Education in the European Union

    ERIC Educational Resources Information Center

    Jones, Peter

    2010-01-01

    This article critically examines the work of the European Commission-sponsored network, the European Expert Network on Economics of Education (EENEE). The aim is to develop understanding of the context and significance of the mobilization of the economics of education research and policy paradigm within the European Union's Education and Training…

  20. Employment and Status of Teachers in State Schools in the European Community. Analysis.

    ERIC Educational Resources Information Center

    EURYDICE Central Unit, Brussels (Belgium).

    The educational systems of the European Community Member States vary considerably and comprise a wealth of information about innovations in these nations. Tables on the employment and status of teachers in state schools in the European Community were compiled at the request of the Commission of the European Communities. The information collected…

  1. Commission 41: History of Astronomy

    NASA Astrophysics Data System (ADS)

    Gurshtein, Alexander A.; Nha, Il-Seong; Ruggles, Clive L. N.; DeVorkin, David H.; Dick, Wolfgang R.; Kochhar, Rajesh; Nakamura, Tsuko; Pigatto, Luisa; Stephenson, F. Richard; Warner, Brian

    2007-12-01

    On Tuesday 22 August 2006 approximately 40 people attended the Commission 41 History of Astronomy Business Meeting at the IAU XXVI General Assembly in Prague. Commission president Alex Gurshtein opened the meeting, welcoming the commission members and calling for a moment of silence for those members who passed away in the last triennium. David DeVorkin was appointed recording secretary for the meeting, with Steven Dick as the scruitineer of the ballot. A moment of silence was then observed in the memory of members departed over the last triennium, including: Jerzy Dobrzycki (Poland), Robert Duncan (Australia), Mohammad Edalati (Iran), Philip Morrison (USA), John Perdix (Australia), Neil Porter (Ireland), Gibson Reaves (USA), Brian Robinson (Australia), and Raymond E. White (USA).

  2. Law sets up oceans commission

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    In an anticipated move, U.S. President Bill Clinton on August 7 signed into law the Oceans Act of 2000.The bipartisan legislation, which takes effect on January 20,2001, establishes a commission on ocean policy to examine federal ocean policy and environmental and economic trends affecting oceans and coasts.The act—which grew out of a call issued by Clinton at the National Oceans Conference in Monterey, California in 1998—requires the commission to submit recommendations to Congress and the president within 18 months of its appointment, and for the President to submit proposals to Congress about the use and stewardship of ocean and coastal resources.

  3. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in...

  4. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same...

  5. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false The Commission. 1.11 Section 1.11 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters § 1.11 The Commission. (a) The Nuclear Regulatory Commission, composed of five members, one of whom is designated by...

  6. 45 CFR 702.18 - Commission reports.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Commission reports. 702.18 Section 702.18 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS RULES ON HEARINGS, REPORTS, AND MEETINGS OF THE COMMISSION Hearings and Reports § 702.18 Commission reports. (a) If...

  7. Federal Communications Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Part XVIII Federal Communications Commission Semiannual Regulatory Agenda ] FEDERAL COMMUNICATIONS COMMISSION (FCC) FEDERAL COMMUNICATIONS COMMISSION 47 CFR Ch. I Unified Agenda of Federal Regulatory and Deregulatory Actions AGENCY: Federal Communications Commission. ACTION: Semiannual regulatory agenda. SUMMARY: Twice a year, in spring and...

  8. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false The Commission. 2101.10 Section 2101.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION OF FINE ARTS FUNCTIONS AND ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members,...

  9. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same...

  10. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in...

  11. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in...

  12. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false The Commission. 1.11 Section 1.11 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters § 1.11 The Commission. (a) The Nuclear Regulatory Commission, composed of five members, one of whom is designated by...

  13. 10 CFR 110.91 - Commission consultations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Commission consultations. 110.91 Section 110.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND MATERIAL Public Participation Procedures Concerning License Applications § 110.91 Commission consultations. The Commission...

  14. European Cosmic Ray Symposium

    SciTech Connect

    2008-04-01

    13me Symposium qui se déroule du 27 au 31 juillet pour la première fois au Cern. Brian Pattison ouvre la cérémonie et donne la parole à Dr.Ugland (qui représente le DG C.Rubbia excusé) et d'autres intervenants

  15. Houston READ Commission Success Stories.

    ERIC Educational Resources Information Center

    Houston READ Commission, TX.

    This document highlights some of the success stories resulting from the activities of the Houston READ Commission (HRC), a nonprofit urban literacy coalition created by the Mayor and City Council of the Greater Houston area. It relates the stories of "those who are the future," lists gifts which support HRC programs, and donors and…

  16. 2-Amino-2-deoxy-glucose conjugated cobalt ferrite magnetic nanoparticle (2DG-MNP) as a targeting agent for breast cancer cells.

    PubMed

    Aşık, Elif; Aslan, Tuğba Nur; Volkan, Mürvet; Güray, N Tülin

    2016-01-01

    In this study, 2-amino-2-deoxy-glucose (2DG) was conjugated to COOH modified cobalt ferrite magnetic nanoparticles (COOH-MNPs), which were designed to target tumor cells as a potential targetable drug/gene delivery agent for cancer treatment. According to our results, it is apparent that, 2DG labeled MNPs were internalized more efficiently than COOH-MNPs under the same conditions in all cell types (MDA-MB-231 and MCF-7 cancer and MCF-10A normal breast cells) (p<0.001). Moreover, the highest amount of uptake was observed in MDA-MB-231, followed by MCF-7 and normal MCF-10A cells for both MNPs. The apoptotic effects of 2DG-MNPs were further evaluated, and it was found that apoptosis was not induced at low concentrations of 2DG-MNPs in all cell types, whereas dramatic cell death was observed at higher concentrations. In addition, the gene expression levels of four drug-metabolizing enzymes, two Phase I (CYP1A1, CYP1B1) and two Phase II (GSTM3, GSTZ1) were also increased with the high concentrations of 2DG-MNPs.

  17. 75 FR 11166 - Joint Meeting of the Nuclear Regulatory Commission and the Federal Energy Regulatory Commission...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Federal Energy Regulatory Commission Joint Meeting of the Nuclear Regulatory Commission and the Federal Energy Regulatory Commission; Notice of Joint Meeting of the Nuclear Regulatory Commission and the... the Nuclear Regulatory Commission (NRC) will hold a joint meeting on Tuesday, March 16, 2010 at...

  18. Sentinel-3A: first commissioning results of its optical payload

    NASA Astrophysics Data System (ADS)

    Nieke, J.; Mavrocordatos, C.; Berruti, B.

    2016-10-01

    The Sentinel-3A satellite, the first of a series of four satellites from the European Commission's Copernicus Programme, was launched on the 16th of February 2016. Sentinel-3 is a multi-instrument mission to measure sea-surface topography, sea- and land-surface temperature, ocean colour and land colour to support ocean forecasting systems, as well as environmental and climate monitoring. The presentation will focus on Sentinel-3 optical instruments, namely the Ocean Land Colour Imager (OLCI) and the Sea and Land Surface Temperature Radiometer (SLSTR). The results of the five-month commissioning phase (concluded in July 2016) are presented. The Level-1 product quality is presented as well as preliminary verification and validation results of the Level-2 ocean products.

  19. Commissioning of the LCLS LINAC

    SciTech Connect

    Loos, H.; Akre, R.; Brachmann, A.; Decker, F.-J.; Ding, Y.; Dowell, D.; Emma, P.; Frisch, J.; Gilevich, S.; Hays, G.; Hering, Ph.; Huang, Z.; Iverson, R.; Limborg-Deprey, C.; Miahnahri, A.; Molloy, S.; Nuhn, H.-D.; Turner, J.; Welch, J.; White, W.; Wu, J.; /SLAC /Stanford U., Appl. Phys. Dept.

    2010-06-11

    The Linac Coherent Light Source (LCLS) X-ray free electron laser project is currently under construction at the Stanford Linear Accelerator Center (SLAC). A new injector and upgrades to the existing accelerator were installed in two phases in 2006 and 2007. We report on the commissioning of the injector, the two new bunch compressors at 250MeV and 4.3 GeV, and transverse and longitudinal beam diagnostics up to the end of the existing linac at 13.6 GeV. The commissioning of the new transfer line from the end of the linac to the undulator is scheduled to start in November 2008 and for the undulator in March 2009 with first light to be expected in July 2009.

  20. High order WENO and DG methods for time-dependent convection-dominated PDEs: A brief survey of several recent developments

    NASA Astrophysics Data System (ADS)

    Shu, Chi-Wang

    2016-07-01

    For solving time-dependent convection-dominated partial differential equations (PDEs), which arise frequently in computational physics, high order numerical methods, including finite difference, finite volume, finite element and spectral methods, have been undergoing rapid developments over the past decades. In this article we give a brief survey of two selected classes of high order methods, namely the weighted essentially non-oscillatory (WENO) finite difference and finite volume schemes and discontinuous Galerkin (DG) finite element methods, emphasizing several of their recent developments: bound-preserving limiters for DG, finite volume and finite difference schemes, which address issues in robustness and accuracy; WENO limiters for DG methods, which address issues in non-oscillatory performance when there are strong shocks, and inverse Lax-Wendroff type boundary treatments for finite difference schemes, which address issues in solving complex geometry problems using Cartesian meshes.

  1. 78 FR 57818 - Commission Participation and Commission Employee Involvement in Voluntary Standards Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY... Standards Activities AGENCY: Consumer Product Safety Commission. ACTION: Notice of proposed rulemaking. SUMMARY: The United States Consumer Product Safety Commission (Commission or CPSC) is issuing a...

  2. Candidatus Frankia Datiscae Dg1, the Actinobacterial Microsymbiont of Datisca glomerata, Expresses the Canonical nod Genes nodABC in Symbiosis with Its Host Plant.

    PubMed

    Persson, Tomas; Battenberg, Kai; Demina, Irina V; Vigil-Stenman, Theoden; Vanden Heuvel, Brian; Pujic, Petar; Facciotti, Marc T; Wilbanks, Elizabeth G; O'Brien, Anna; Fournier, Pascale; Cruz Hernandez, Maria Antonia; Mendoza Herrera, Alberto; Médigue, Claudine; Normand, Philippe; Pawlowski, Katharina; Berry, Alison M

    2015-01-01

    Frankia strains are nitrogen-fixing soil actinobacteria that can form root symbioses with actinorhizal plants. Phylogenetically, symbiotic frankiae can be divided into three clusters, and this division also corresponds to host specificity groups. The strains of cluster II which form symbioses with actinorhizal Rosales and Cucurbitales, thus displaying a broad host range, show suprisingly low genetic diversity and to date can not be cultured. The genome of the first representative of this cluster, Candidatus Frankia datiscae Dg1 (Dg1), a microsymbiont of Datisca glomerata, was recently sequenced. A phylogenetic analysis of 50 different housekeeping genes of Dg1 and three published Frankia genomes showed that cluster II is basal among the symbiotic Frankia clusters. Detailed analysis showed that nodules of D. glomerata, independent of the origin of the inoculum, contain several closely related cluster II Frankia operational taxonomic units. Actinorhizal plants and legumes both belong to the nitrogen-fixing plant clade, and bacterial signaling in both groups involves the common symbiotic pathway also used by arbuscular mycorrhizal fungi. However, so far, no molecules resembling rhizobial Nod factors could be isolated from Frankia cultures. Alone among Frankia genomes available to date, the genome of Dg1 contains the canonical nod genes nodA, nodB and nodC known from rhizobia, and these genes are arranged in two operons which are expressed in D. glomerata nodules. Furthermore, Frankia Dg1 nodC was able to partially complement a Rhizobium leguminosarum A34 nodC::Tn5 mutant. Phylogenetic analysis showed that Dg1 Nod proteins are positioned at the root of both α- and β-rhizobial NodABC proteins. NodA-like acyl transferases were found across the phylum Actinobacteria, but among Proteobacteria only in nodulators. Taken together, our evidence indicates an Actinobacterial origin of rhizobial Nod factors.

  3. Candidatus Frankia Datiscae Dg1, the Actinobacterial Microsymbiont of Datisca glomerata, Expresses the Canonical nod Genes nodABC in Symbiosis with Its Host Plant

    PubMed Central

    Persson, Tomas; Battenberg, Kai; Demina, Irina V.; Vigil-Stenman, Theoden; Vanden Heuvel, Brian; Pujic, Petar; Facciotti, Marc T.; Wilbanks, Elizabeth G.; O'Brien, Anna; Fournier, Pascale; Cruz Hernandez, Maria Antonia; Mendoza Herrera, Alberto; Médigue, Claudine; Normand, Philippe; Pawlowski, Katharina; Berry, Alison M.

    2015-01-01

    Frankia strains are nitrogen-fixing soil actinobacteria that can form root symbioses with actinorhizal plants. Phylogenetically, symbiotic frankiae can be divided into three clusters, and this division also corresponds to host specificity groups. The strains of cluster II which form symbioses with actinorhizal Rosales and Cucurbitales, thus displaying a broad host range, show suprisingly low genetic diversity and to date can not be cultured. The genome of the first representative of this cluster, Candidatus Frankia datiscae Dg1 (Dg1), a microsymbiont of Datisca glomerata, was recently sequenced. A phylogenetic analysis of 50 different housekeeping genes of Dg1 and three published Frankia genomes showed that cluster II is basal among the symbiotic Frankia clusters. Detailed analysis showed that nodules of D. glomerata, independent of the origin of the inoculum, contain several closely related cluster II Frankia operational taxonomic units. Actinorhizal plants and legumes both belong to the nitrogen-fixing plant clade, and bacterial signaling in both groups involves the common symbiotic pathway also used by arbuscular mycorrhizal fungi. However, so far, no molecules resembling rhizobial Nod factors could be isolated from Frankia cultures. Alone among Frankia genomes available to date, the genome of Dg1 contains the canonical nod genes nodA, nodB and nodC known from rhizobia, and these genes are arranged in two operons which are expressed in D. glomerata nodules. Furthermore, Frankia Dg1 nodC was able to partially complement a Rhizobium leguminosarum A34 nodC::Tn5 mutant. Phylogenetic analysis showed that Dg1 Nod proteins are positioned at the root of both α- and β-rhizobial NodABC proteins. NodA-like acyl transferases were found across the phylum Actinobacteria, but among Proteobacteria only in nodulators. Taken together, our evidence indicates an Actinobacterial origin of rhizobial Nod factors. PMID:26020781

  4. 76 FR 9630 - Notice of Public Hearing and Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Notice of Public Hearing and Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice of public hearing and commission meeting. SUMMARY: The Susquehanna River Basin Commission...

  5. Enhanced plasmid DNA utilization in transiently transfected CHO-DG44 cells in the presence of polar solvents.

    PubMed

    Rajendra, Yashas; Balasubramanian, Sowmya; Kiseljak, Divor; Baldi, Lucia; Wurm, Florian M; Hacker, David L

    2015-01-01

    Although the protein yields from transient gene expression (TGE) with Chinese hamster ovary (CHO) cells have recently improved, the amount of plasmid DNA (pDNA) needed for transfection remains relatively high. We describe a strategy to reduce the pDNA amount by transfecting CHO-DG44 cells with 0.06 μg pDNA/10(6) cells (10% of the optimal amount) in the presence of nonspecific (filler) DNA and various polar solvents including dimethylsufoxide, dimethyl formamide, acetonitrile, dimethyl acetamide (DMA), and hexamethyl phosphoramide (HMP). All of the polar solvents with the exception of HMP increased the production of a recombinant antibody in comparison to the untreated control transfection. In the presence of 0.25% DMA, the antibody yield in a 7-day batch culture was 500 mg/L. This was fourfold higher than the yield from the untreated control transfection. Mechanistic studies revealed that the polar solvents did not affect polyethylenimine-mediated pDNA delivery into cells or nuclei. The steady-state transgene mRNA level was elevated in the presence of each of the polar solvents tested, while the transgene mRNA half-life remained the same. These results indicated that the polar solvents enhanced transgene transcription. When screening a panel of recombinant antibodies and Fc-fusion proteins for production in the presence of the polar solvents, the highest increase in yield was observed following DMA addition for 11 of the 12 proteins. These results are expected to enhance the applicability of high-yielding TGE processes with CHO-DG44 cells by decreasing the amount of pDNA required for transfection.

  6. Blue Ribbon Commission Tour of Hanford Site

    SciTech Connect

    Paul Saueressig

    2010-07-14

    The Blue Ribbon Commission on America's Nuclear Future toured the Department of Energy's Hanford Site on July 14, 2010. Commission members, invited guests, and members of the public visited facilities that store high-level, radioactive waste.

  7. Blue Ribbon Commission Tour of Hanford Site

    ScienceCinema

    Paul Saueressig

    2016-07-12

    The Blue Ribbon Commission on America's Nuclear Future toured the Department of Energy's Hanford Site on July 14, 2010. Commission members, invited guests, and members of the public visited facilities that store high-level, radioactive waste.

  8. E-ELT assembly, integration, and technical commissioning plans

    NASA Astrophysics Data System (ADS)

    Gray, P.; Ciattaglia, E.; Dupuy, C.; Gago, F.; Guisard, S.; Marrero, J.; Ridings, R.; Wright, A.

    2016-07-01

    EELT AIV is the activity of assembly, integration and verification of EELT (European Extremely Large Telescope) subsystems to deliver a telescope capable of fulfilling its top-level requirements and ready to start science commissioning, leading to operations. The AIV (Assembly Integration Verification) phase covers all technical activities on Armazones and nearby Paranal Observatory from the moment the sub-systems and components are delivered or accepted on-site (from the responsible sub-system project manager). AIV includes final system tests of the completed telescope (known as "Technical Commissioning") and the installation, alignment and telescope integration of the science instruments. The AIV phase ends with the handover of the completed telescope with installed instruments, to the start of Science Commissioning. Responsibility then passes to the Commissioning team, however the technical resources for debugging and tuning the telescope and instrument will come from a combination of the AIV team working together with the Paranal operations staff. AIV is one of the major technical challenge of E-ELT. The sheer scale and complexity of the telescope involves challenging logistics and scheduling i.e. 798 mirror segments with a staged delivery over four years, including 9,048 edge sensor and 2,394 position actuators. More than ten major sub-systems e.g. M2-3-4-5, PreFocal Station (PFS) and instruments will be integrated and tested in parallel. Finally, the technical commissioning phase will be a significant challenge. E-ELT is a highly complex active telescope system with a fully-integrated adaptive optics (AO) system. During early testing nothing will be straightforward and there will be many system-level problems to overcome. It will take a dedicated team of the "best of the best" people to troubleshoot, debug, tune, and hand over as an operational facility.

  9. Nuclear Regulatory Commission 1989 Information Digest

    SciTech Connect

    None,

    1989-03-01

    The Nuclear Regulatory Commission 1989 Information Digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the Commission. This is the first of an annual publication for the general use of the NRC staff and is available to the public. The Digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  10. Bioethics commission to review gene patenting

    SciTech Connect

    Rothenburg, L.

    1995-12-01

    In October, in an unexpected development, U.S. President Bill Clinton created a national ethics advisory board, the National Bioethics Advisory Commission (NBAC, Washington, DC), to study both research ethics and the management and use of genetic information. Of particular interest to biotechnology companies and researchers is the fact that the commission`s brief encompasses issues about human gene patenting, a subject not contained in earlier proposals for the commission.

  11. Commissioning Instrument for the GTC

    NASA Astrophysics Data System (ADS)

    Cuevas, S.; Sánchez, B.; Bringas, V.; Espejo, C.; Flores, R.; Chapa, O.; Lara, G.; Chavolla, A.; Anguiano, G.; Arciniega, S.; Dorantes, A.; González, J. L.; Montoya, J. M.; Toral, R.; Hernández, H.; Nava, R.; Devaney, N.; Castro, J.; Cavaller-Marqués, L.

    2005-12-01

    During the GTC integration phase, the Commissioning Instrument (CI) will be a diagnostic tool for performance verification. The CI features four operation modes: imaging, pupil imaging, Curvature WFS, and high resolution Shack-Hartmann WFS. This instrument was built by the Instituto de Astronomía UNAM and the Centro de Ingeniería y Desarrollo Industrial (CIDESI) under GRANTECAN contract after a public bid. In this paper we made a general instrument overview and we show some of the performance final results obtained when the Factory Acceptance tests previous to its transport to La Palma.

  12. Spectroscopic commissioning results from MINERVA

    NASA Astrophysics Data System (ADS)

    Eastman, Jason D.; Johnson, Samson; Wang, Sharon; Sliski, David; Wilson, Maurice; Johnson, John A.; McCrady, Nate; Wittenmyer, Robert A.; Wright, Jason; Plavchan, Peter; Blake, Cullen; Beatty, Thomas G.

    2017-01-01

    MINERVA is a robotic observatory with four 0.7 meter telescopes at Mt. Hopkins, Arizona, dedicated to precise photometry and radial velocity observations of bright, nearby stars for the discovery and characterization of small exoplanets. Here we present the first radial velocity results from MINERVA during commissioning at the Fred Lawrence Whipple Observatory in Arizona, demonstrating m/s precision over month-long timescales. These results show that MINERVA is capable of achieving its primary science goal of finding super-Earths around the nearest, brightest stars.

  13. Photometric commissioning results from MINERVA

    NASA Astrophysics Data System (ADS)

    Eastman, Jason D.; Swift, Jonathan; Beatty, Thomas G.; Bottom, Michael; Johnson, John; Wright, Jason; McCrady, Nate; Wittenmyer, Robert A.; Riddle, Reed L.; Plavchan, Peter; Muirhead, Philip Steven; Blake, Cullen; Zhao, Ming

    2015-01-01

    MINERVA is a robotic observatory with four 0.7 meter telescopes at Mt. Hopkins, Arizona, dedicated to precise photometry and radial velocity observations of bright, nearby stars for the discovery and characterization of small exoplanets. Here we present the first photometric results from MINERVA during commissioning at our test facility in Pasadena, California, demonstrating sub-millimag precision on 3-5 minute timescales over several hours. These results show that MINERVA is well-equipped to address its secondary science goal of searching for transits of known and newly discovered super-Earth exoplanets detected by radial velocity, including potential detections from the MINERVA spectrograph.

  14. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false The Commission. 2101.10 Section 2101.10 Public... ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members, each of whom is appointed by the President and serves for a period of four years or until his or...

  15. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and...

  16. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86...

  17. 76 FR 6774 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-08

    ...This notice sets forth the schedule and proposed agenda of an upcoming meeting of the Equity and Excellence Commission (Commission). The notice also describes the functions of the Commission. Notice of this meeting is required by section 10(a)(2) of the Federal Advisory Committee Act (FACA) and is intended to notify the public of their opportunity to...

  18. 43 CFR 10010.41 - Commission responsibility.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... environmental document may be prepared by the Commission, a joint-lead agency, a contractor selected or approved... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Commission responsibility. 10010.41... MITIGATION AND CONSERVATION COMMISSION POLICIES AND PROCEDURES FOR IMPLEMENTING THE NATIONAL...

  19. Commissioning services and Primary Health Networks.

    PubMed

    Booth, Mark; Boxall, Anne-Marie

    2016-01-01

    Commissioning is set to become a stronger feature in the Australian health system as Primary Health Networks embrace it as a tool for improving population health outcomes. International experience shows that developing into a commissioning organisation is not always easy. Drawing on international experiences of commissioning, as well as those from the Australian hospital sector, will help smooth the path for Primary Health Networks.

  20. 16 CFR 1101.51 - Commission interpretation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Commission interpretation. 1101.51 Section 1101.51 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.51 Commission interpretation. (a)...

  1. 77 FR 39560 - International Joint Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... International Joint Commission International Joint Commission Invites Public Comment on Upper Great Lakes Report The International Joint Commission (IJC) announced today that it is inviting public comment on the final report of its International Upper Great Lakes Study Board, Lake Superior Regulation:...

  2. 77 FR 29621 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    .... ADDRESSES: The Commission will meet in Washington, DC at the United States Department of Education at 400... Doc No: 2012-12144] DEPARTMENT OF EDUCATION Equity and Excellence Commission AGENCY: U.S. Department..., Designated Federal Official, Equity and Excellence Commission, U.S. Department of Education, 400...

  3. 77 FR 10004 - CFC-50 Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... MANAGEMENT CFC-50 Commission AGENCY: Office of Personnel Management. ACTION: Establishment of advisory committee. SUMMARY: The CFC-50 Advisory Commission will hold its third and final meeting on March 2, 2012... Federal Campaign (CFC) to ensure its continued growth and success. The Commission is an advisory...

  4. 76 FR 53159 - CFC-50 Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ... MANAGEMENT CFC-50 Commission Meeting AGENCY: Office of Personnel Management. ACTION: Establishment of advisory committee. SUMMARY: The CFC-50 Advisory Commission will hold its initial meeting on September 13... Combined Federal Campaign (CFC) to ensure its continued growth and success. The Commission is an...

  5. Commissions, Reports, Reforms, and Educational Policy.

    ERIC Educational Resources Information Center

    Ginsberg, Rick, Ed.; Plank, David N., Ed.

    "Blue-ribbon" commissions are an increasingly common feature of the American political landscape. This book examines the roles that blue-ribbon commissions and their reports have played in educational policymaking. The book begins with a foreword by Paul E. Peterson and an introductory chapter, "Commissions and Change" by Rick Ginsberg and David…

  6. 75 FR 18469 - April 2010 Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ...; ] EXECUTIVE OFFICE OF THE PRESIDENT National Commission on Fiscal Responsibility and Reform April 2010...), the National Commission on Fiscal Responsibility and Reform announces the following meeting: Name: National Commission on Fiscal Responsibility and Reform April 2010 Meeting. Time and Date: Tuesday,...

  7. Iowa College Student Aid Commission Case Study

    ERIC Educational Resources Information Center

    Leigh, Rachel A.

    2007-01-01

    The purpose of this descriptive case study was to trace the policy production process of a state agency, the Iowa College Student Aid Commission (Commission), to its function today. This case study relied on a review of federal and state statutes, a news article search, biennium reports of the Commission, and information obtained from the…

  8. 78 FR 44927 - 101st Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... From the Federal Register Online via the Government Publishing Office ARCTIC RESEARCH COMMISSION 101st Commission Meeting Notice is hereby given that the U.S. Arctic Research Commission will hold its... presentations concerning Arctic research activities The focus of the meeting will be Arctic research...

  9. 10 CFR 2.1331 - Commission action.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Commission action. 2.1331 Section 2.1331 Energy NUCLEAR... for Hearings on License Transfer Applications § 2.1331 Commission action. (a) Upon completion of a hearing, the Commission will issue a written opinion including its decision on the license...

  10. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  11. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  12. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  13. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  14. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  15. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and...

  16. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false The Commission. 2101.10 Section 2101.10 Public... ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members, each of whom is appointed by the President and serves for a period of four years or until his or...

  17. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and...

  18. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and...

  19. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86...

  20. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86...

  1. 46 CFR 502.161 - Commission's files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Commission's files. 502.161 Section 502.161 Shipping...; Presiding Officers; Evidence § 502.161 Commission's files. Where any matter contained in a tariff, report, or other document on file with the Commission is offered in evidence, such document need not...

  2. European Cosmic Ray Symposium

    ScienceCinema

    None

    2016-07-12

    13me Symposium qui se déroule du 27 au 31 juillet pour la première fois au Cern. Brian Pattison ouvre la cérémonie et donne la parole à Dr.Ugland (qui représente le DG C.Rubbia excusé) et d'autres intervenants

  3. Beyond Commissioning: The Role of Automation

    SciTech Connect

    Brambley, Michael R.; Katipamula, Srinivas

    2005-02-01

    This article takes a brief look at the benefits of commissioning and describes a vision of the future where most of the objectives of commissioning will be accomplished automatically by capabilities built into the building systems themselves. Commissioning will become an activity that's performed continuously rather than periodically, and only repairs requiring replacement or overhaul of equipment will require manual intervention. The article then identifies some of the technologies that will be needed to realize this vision and ends with a call for all involved in the enterprise of building commissioning and automation to embrace and dedicate themselves to a future of automated commissioning.

  4. ACCUMULATION OF M1DG DNA ADDUCTS AFTER CHRONIC EXPOSURE TO PCBS, BUT NOT FROM ACUTE EXPOSURE TO DIOXIN-LIKE COMPOUNDS

    EPA Science Inventory

    ABSTRACT: Oxidative DNA damage is one of the key events leading to mutation and cancer. The present study examined the accumulation of M1dG DNA adducts, 3-(2’-deoxy-β-D-erythro-pentofuranosyl)-pyrimido[1,2-a]-purin-10(3H)-one, after single or yearly exposur...

  5. Notice of Release of WhiteAcre-DG, a Small-seeded, Cream-type Southernpea with an Enhanced Persistent Green Seed Phenotype

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The USDA has developed a high yielding, small-seeded, cream-type southernpea cultivar that has a persistent green seed phenotype conditioned by both the green cotyledon gene (gc) and the green testa gene (gt). The new cultivar, named WhiteAcre-DG, can be harvested at the dry-pod stage of maturity w...

  6. Overexpression of a novel chrysanthemum Cys2/His2-type zinc finger protein gene DgZFP3 confers drought tolerance in tobacco.

    PubMed

    Liu, Qing-Lin; Xu, Ke-Dong; Zhong, Ming; Pan, Yuan-Zhi; Jiang, Bei-Bei; Liu, Guang-Li; Jia, Yin; Zhang, Hai-Qing

    2013-11-01

    A drought stress-responsive Cys2/His2-type zinc finger protein gene DgZFP3 was previously isolated (Liu et al., Afr J Biotechnol 11:7781-7788, 2012b) from chrysanthemum. To assess roles of DgZFP3 in plant drought stress responses, we performed gain-of-function experiment. The DgZFP3-overexpression tobacco plants showed significant drought tolerance over the wild type (WT). The transgenic lines exhibited less accumulation of H2O2 under drought stress, more accumulation of proline and greater activities of peroxidase (POD) and superoxide dismutase than the WT under both control conditions and drought stress. In addition, there was greater up-regulation of the ROS-related enzyme genes (NtSOD and NtPOD) and stress-related genes (NtLEA5 and NtDREB) in transgenic lines under normal or drought conditons. Thus DgZFP3 probably plays a positive regulatory role in drought stress response and has the potential to be utilized in transgenic breeding to improve drought stress tolerance in plants.

  7. A multi-dimensional high-order DG-ALE method based on gas-kinetic theory with application to oscillating bodies

    NASA Astrophysics Data System (ADS)

    Ren, Xiaodong; Xu, Kun; Shyy, Wei

    2016-07-01

    This paper presents a multi-dimensional high-order discontinuous Galerkin (DG) method in an arbitrary Lagrangian-Eulerian (ALE) formulation to simulate flows over variable domains with moving and deforming meshes. It is an extension of the gas-kinetic DG method proposed by the authors for static domains (X. Ren et al., 2015 [22]). A moving mesh gas kinetic DG method is proposed for both inviscid and viscous flow computations. A flux integration method across a translating and deforming cell interface has been constructed. Differently from the previous ALE-type gas kinetic method with piecewise constant mesh velocity at each cell interface within each time step, the mesh velocity variation inside a cell and the mesh moving and rotating at a cell interface have been accounted for in the finite element framework. As a result, the current scheme is applicable for any kind of mesh movement, such as translation, rotation, and deformation. The accuracy and robustness of the scheme have been improved significantly in the oscillating airfoil calculations. All computations are conducted in a physical domain rather than in a reference domain, and the basis functions move with the grid movement. Therefore, the numerical scheme can preserve the uniform flow automatically, and satisfy the geometric conservation law (GCL). The numerical accuracy can be maintained even for a largely moving and deforming mesh. Several test cases are presented to demonstrate the performance of the gas-kinetic DG-ALE method.

  8. 77 FR 41877 - International Joint Commission; International Joint Commission To Hold Public Hearings on Lake...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ... International Joint Commission; International Joint Commission To Hold Public Hearings on Lake Osoyoos The International Joint Commission (IJC) is inviting the public to comment on recommendations for the renewal of its... of the International Joint Commission's Osoyoos Lake Order now posted on the IJC Web site at...

  9. Transcriptional analysis of degenerate strain Clostridium beijerinckii DG-8052 reveals a pleiotropic response to CaCO3-associated recovery of solvent production

    PubMed Central

    Jiao, Shengyin; Zhang, Yan; Wan, Caixia; Lv, Jia; Du, Renjia; Zhang, Ruijuan; Han, Bei

    2016-01-01

    Degenerate Clostridium beijerinckii strain (DG-8052) can be partially recovered by supplementing CaCO3 to fermentation media. Genome resequencing of DG-8052 showed no general regulator mutated. This study focused on transcriptional analysis of DG-8052 and its response to CaCO3 treatment via microarray. The expressions of 5168 genes capturing 98.6% of C. beijerinckii NCIMB 8052 genome were examed. The results revealed that with addition of CaCO3 565 and 916 genes were significantly up-regulated, and 704 and 1044 genes significantly down-regulated at acidogenic and solventogenic phase of DG-8052, respectively. These genes are primarily responsible for glycolysis to solvent/acid production (poR, pfo), solventogensis (buk, ctf, aldh, adh, bcd) and sporulation (spo0A, sigE, sigma-70, bofA), cell motility and division (ftsA, ftsK, ftsY, ftsH, ftsE, mreB, mreC, mreD, rodA), and molecular chaperones (grpE, dnaK, dnaJ, hsp20, hsp90), etc. The functions of some altered genes in DG-8052, totalling 5.7% at acidogenisis and 8.0% at sovlentogenisis, remain unknown. The response of the degenerate strain to CaCO3 was suggested significantly pleiotropic. This study reveals the multitude of regulatory function that CaCO3 has in clostridia and provides detailed insights into degeneration mechanisms at gene regulation level. It also enables us to develop effective strategies to prevent strain degeneration in future. PMID:27966599

  10. Physical properties of the jet from DG Tauri on sub-arcsecond scales with HST/STIS

    NASA Astrophysics Data System (ADS)

    Maurri, L.; Bacciotti, F.; Podio, L.; Eislöffel, J.; Ray, T. P.; Mundt, R.; Locatelli, U.; Coffey, D.

    2014-05-01

    Context. Stellar jets are believed to play a key role in star formation, but the question of how they originate is still being debated. Aims: We derive the physical properties at the base of the jet from DG Tau both along and across the flow and as a function of velocity. Methods: We analysed seven optical spectra of the DG Tau jet, taken with the Hubble Space Telescope Imaging Spectrograph. The spectra were obtained by placing a long-slit parallel to the jet axis and stepping it across the jet width. The resulting position-velocity diagrams in optical forbidden emission lines allowed access to plasma conditions via calculation of emission line ratios. In this way, we produced a 3D map (2D in space and 1D in velocity) of the jet's physical parameters i.e. electron density ne, hydrogen ionisation fraction xe, and total hydrogen density nH. The method used is a new version of the BE-technique. Results: A fundamental improvement is that the new diagnostic method allows us to overcome the upper density limit of the standard [S ii] diagnostics. As a result, we find at the base of the jet high electron density, ne ~ 105, and very low ionisation, xe ~ 0.02-0.05, which combine to give a total density up to nH ~ 3 × 106. This analysis confirms previous reports of variations in plasma parameters along the jet, (i.e. decrease in density by several orders of magnitude, increase of xe from 0.05 to a plateau at 0.7 downstream at 2'' from the star). Furthermore, a spatial coincidence is revealed between sharp gradients in the total density and supersonic velocity jumps. This strongly suggests that the emission is caused by shock excitation. No evidence was found of variations in the parameters across the jet, within a given velocity interval. The position-velocity diagrams indicate the presence of both fast accelerating gas and slower, less collimated material. We derive the mass outflow rate, Ṁj, in the blue-shifted lobe in different velocity channels, that contribute to a

  11. Automated Demand Response and Commissioning

    SciTech Connect

    Piette, Mary Ann; Watson, David S.; Motegi, Naoya; Bourassa, Norman

    2005-04-01

    This paper describes the results from the second season of research to develop and evaluate the performance of new Automated Demand Response (Auto-DR) hardware and software technology in large facilities. Demand Response (DR) is a set of activities to reduce or shift electricity use to improve the electric grid reliability and manage electricity costs. Fully-Automated Demand Response does not involve human intervention, but is initiated at a home, building, or facility through receipt of an external communications signal. We refer to this as Auto-DR. The evaluation of the control and communications must be properly configured and pass through a set of test stages: Readiness, Approval, Price Client/Price Server Communication, Internet Gateway/Internet Relay Communication, Control of Equipment, and DR Shed Effectiveness. New commissioning tests are needed for such systems to improve connecting demand responsive building systems to the electric grid demand response systems.

  12. Division A Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Hosokawa, Mizuhiko; Arias, Elisa Felicitas; Manchester, Richard; Tuckey, Philip; Matsakis, Demetrios; Zhang, Shougang; Zharov, Vladimir

    2016-04-01

    Time is an essential element of fundamental astronomy. In recent years there have been many time-related issues, in scientific and technological aspects as well as in conventions and definitions. At the Commission 31 (Time) business meeting at the XXIX General Assembly, recent progress and many topics, including Pulsar Time Scales WG and Future UTC WG activities, were reviewed and discussed. In this report, we will review the progress of these topics in the past three years. There are many remarkable topics, such as Time scales, Atomic clock development, Time transfer, Future UTC and future redefinition of the second. Among them, scientific highlights are the progress of pulsar time scales and the optical frequency standards. On the other hand, as the social convention, change in the definition of UTC and the second is important.

  13. Orion: a commissioned user facility

    NASA Astrophysics Data System (ADS)

    Treadwell, P. A.; Allan, P.; Cann, N.; Danson, C.; Duffield, S.; Elsmere, S.; Edwards, R.; Egan, D.; Girling, M.; Gumbrell, E.; Harvey, E.; Hill, M.; Hillier, D.; Hoarty, D.; Hobbs, L.; Hopps, N.; Hussey, D.; Oades, K.; James, S.; Norman, M.; Palmer, J.; Parker, S.; Winter, D.; Bett, T.

    2013-05-01

    The Orion Laser Facility at AWE in the UK consists of ten nanosecond beamlines and two sub-picosecond beamlines. The nanosecond beamlines each nominally deliver 500 J at 351 nm in a 1 ns square temporal profile, but can also deliver a user-definable temporal profile with durations between 0.1 ns and 5 ns. The sub-picosecond beamlines each nominally deliver 500 J at 1053 nm in a 500 fs pulse, with a peak irradiance of greater than 1021 W/cm2. One of the sub-picosecond beamlines can also be frequency-converted to deliver 100 J at 527 nm in a 500 fs pulse, although this is at half the aperture of the 1053 nm beam. Commissioning of all twelve beamlines has been completed, including the 527 nm sub-picosecond option. An overview of the design of the Orion beamlines will be presented, along with a summary of the commissioning and subsequent performance data. The design of Orion was underwritten by running various computer simulations of the beamlines. Work is now underway to validate these simulations against real system data, with the aim of creating predictive models of beamline performance. These predictive models will enable the user's experimental requirements to be critically assessed ahead of time, and will ultimately be used to determine key system settings and parameters. The facility is now conducting high energy density physics experiments. A capability experiment has already been conducted that demonstrates that Orion can generate plasmas at several million Kelvin and several times solid density. From March 2013 15% of the facility operating time will be given over to external academic users in addition to collaborative experiments with AWE scientists.

  14. Drain Current Model for Double Gate (DG) p-n-i-n TFET: Accumulation to Inversion Region of Operation

    NASA Astrophysics Data System (ADS)

    Upasana; Narang, Rakhi; Saxena, Manoj; Gupta, Mridula

    2017-04-01

    In this paper, drain current model has been formulated for Double Gate (DG) p-n-i-n Tunnel FET (TFET) using Lambert-W function. The model includes the impact of mobile charges, gate dielectric thickness (tox) and channel thickness (tsi) on quasi fermi level, gate threshold voltage (VTG), onset voltage (VGonset) and Tunneling Barrier Width (TBW) over the entire operating range i.e. accumulation to inversion state. Important electrostatic and electrical parameters such as the effective potential (φeffective) at the center of the channel, 2-D channel potential, electric field, energy band profile and Tunneling Barrier Width (TBW) dependent drain current have been modeled. Moreover, gate and drain bias controllability in different operating regimes has also been investigated by varying oxide thickness (tox), channel thickness (tsi), intrinsic channel length (Lint) and at different temperatures. Important FOMs required for analog circuit performance such as transconductance (gm), drain conductance (gd), output resistance (Rout), early voltage (VEA) have also been evaluated and verified using ATLAS device simulation software.

  15. Simulating Large-Scale Earthquake Dynamic Rupture Scenarios On Natural Fault Zones Using the ADER-DG Method

    NASA Astrophysics Data System (ADS)

    Gabriel, Alice; Pelties, Christian

    2014-05-01

    In this presentation we will demonstrate the benefits of using modern numerical methods to support physic-based ground motion modeling and research. For this purpose, we utilize SeisSol an arbitrary high-order derivative Discontinuous Galerkin (ADER-DG) scheme to solve the spontaneous rupture problem with high-order accuracy in space and time using three-dimensional unstructured tetrahedral meshes. We recently verified the method in various advanced test cases of the 'SCEC/USGS Dynamic Earthquake Rupture Code Verification Exercise' benchmark suite, including branching and dipping fault systems, heterogeneous background stresses, bi-material faults and rate-and-state friction constitutive formulations. Now, we study the dynamic rupture process using 3D meshes of fault systems constructed from geological and geophysical constraints, such as high-resolution topography, 3D velocity models and fault geometries. Our starting point is a large scale earthquake dynamic rupture scenario based on the 1994 Northridge blind thrust event in Southern California. Starting from this well documented and extensively studied event, we intend to understand the ground-motion, including the relevant high frequency content, generated from complex fault systems and its variation arising from various physical constraints. For example, our results imply that the Northridge fault geometry favors a pulse-like rupture behavior.

  16. Status of European appliance standards

    SciTech Connect

    Turiel, I.; Lebot, B.

    1992-05-01

    The European Community (EC) recently commissioned a study of the impact of potential appliance standards on electricity consumption in the twelve EC nations. This study looks at refrigerators, freezers, dishwashers, clothes washers, and clothes dryers. The impact of minimum efficiency standards on electricity use over the time period from 1995--2010 is estimated. The results of this study were presented to the EC in September of 1991. Revisions were made to the draft report and final copies sent to all interested parties. The member nations of the EC will soon consider whether they wish to implement uniform energy efficiency standards that would take effect in 1995. The results of the study described above will be presented and the political considerations will be discussed. In addition, data describing the appliance market in Europe will be presented.

  17. Commissioning Results on the JWST Testbed Telescope

    NASA Technical Reports Server (NTRS)

    Dean, Bruce H.; Acton, D. Scott

    2006-01-01

    The one-meter 18 segment JWST Testbed Telescope (TBT) has been developed at Ball Aerospace to facilitate commissioning operations for the JWST Observatory. Eight different commissioning activities were tested on the TBT: telescope focus sweep, segment ID and Search, image array, global alignment, image stacking, coarse phasing, fine phasing, and multi-field phasing. This paper describes recent commissioning results from experiments performed on the TBT.

  18. The European Location Framework - from National to European

    NASA Astrophysics Data System (ADS)

    Pauknerova, E.; Sidlichovsky, P.; Urbanas, S.; Med, M.

    2016-06-01

    The European Location Framework (ELF) means a technical infrastructure which will deliver authoritative, interoperable geospatial reference data from all over Europe for analysing and understanding information connected to places and features. The ELF has been developed and set up through the ELF Project, which has been realized by a consortium of partners (public, private and academic organisations) since March 2013. Their number increased from thirty to forty in the year 2016, together with a project extension from 36 to 44 months. The project is co-funded by the European Commission's Competitiveness and Innovation Framework Programme (CIP) and will end in October 2016. In broad terms, the ELF Project will deliver a unique gateway to the authoritative reference geospatial information for Europe (harmonised pan-European maps, geographic and land information) sourced from the National Mapping and Cadastral Authorities (NMCAs) around Europe and including transparent licensing. This will be provided as an online ELF web service that will deliver an up-to-date topographic base map and also as view & download services for access to the ELF datasets. To develop and build up the ELF, NMCAs are accompanied and collaborate with several research & academia institutes, a standardisation body, system integrators, software developers and application providers. The harmonisation is in progress developing and triggering a number of geo-tools like edge-matching, generalisation, transformation and others. ELF will provide also some centralised tools like Geo Locator for searching location based on geographical names, addresses and administrative units, and GeoProduct Finder for discovering the available web-services and licensing them. ELF combines national reference geo-information through the ELF platform. ELF web services will be offered to users and application developers through open source (OSKARI) and proprietary (ArcGIS Online) cloud platforms. Recently, 29 NMCAs plus the

  19. 78 FR 44165 - Nuclear Regulatory Commission Enforcement Policy

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Nuclear Regulatory Commission Enforcement Policy AGENCY: Nuclear Regulatory Commission. ACTION: Enforcement policy; request for comment. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is...

  20. The ECO European Project: A New MOOC Dimension Based on an Intercreativity Environment

    ERIC Educational Resources Information Center

    Acedo, Sara Osuna; Cano, Lucía Camarero

    2016-01-01

    The ECO European Project funded by the European Commission is dedicated to bringing MOOCs to a new dimension by taking advantage of the new possibilities offered by the Social Web (O'Reilly, 2005). This paper focuses on the intercreative aspects of MOOCs. It takes a look at the characteristics of the new ECO MOOCs to see if they are designed and…

  1. Proposal for National Targets in the Framework of the European Reduction Goal for Early School Leaving

    ERIC Educational Resources Information Center

    Lastra-Bravo, Xavier B.; Tolón-Becerra, Alfredo; Salinas-Andújar, José A.

    2013-01-01

    According to the European Commission's "Europe 2020" strategy, the early school leaving (ESL) rate in European Union (EU) Member States must be reduced to a maximum of 10 per cent by 2020. This paper proposes a nonlinear distribution method based on dynamic targets for reducing the percentage of early school leavers. The aim of this…

  2. The Practice of Media Education: International Research on Six European Countries

    ERIC Educational Resources Information Center

    Parola, Alberto; Ranieri, Maria

    2011-01-01

    This paper presents and discusses the results of OnAir, a European project on Media Education funded by the European Commission. This two-year project aimed at collecting, documenting, and developing media education practices across Europe, especially in Belgium, Bulgaria, Italy, Lithuania, Poland, and Romania. In particular, the paper focuses on…

  3. European Master's Program in Gerontology (EuMaG): Goals, Curriculum, and Students

    ERIC Educational Resources Information Center

    Aartsen, Marja

    2011-01-01

    The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four domains of gerontology (i.e., social gerontology,…

  4. Conducting Research into European Union Education and Training Policy: Some Theoretical and Methodological Considerations.

    ERIC Educational Resources Information Center

    Phillips, David; Economou, Anastasia

    1999-01-01

    Discusses PRESTIGE, the project funded by the European Commission within its Training and Mobility Researchers program, describing the research design of the Oxford part of the project. Describes a comparative study of the implementation of the 'European Dimension' in education in England, Scotland, and Wales. Considers the methodological and…

  5. The application of the European Convention of Human Rights to the field of psychiatry.

    PubMed

    Harding, T W

    1990-01-01

    The European Convention of Human Rights enumerates a set of individual rights and fundamental freedoms and defines supra-national legal procedures whereby individuals, who believe themselves victims of human rights abuses and are unable to gain redress through domestic courts, can petition the European Commission of Human Rights.

  6. Small Boats in an Ocean of School Activities: Towards a European Vision on Education

    ERIC Educational Resources Information Center

    Villalba, Ernesto

    2008-01-01

    The paper discusses the concept of schools as "multi-purpose learning centres", proposed by the European Commission in the year 2000 as part of the Lisbon Strategy to improve competitiveness. This concept was arguably the "European vision" for school education and was meant to drive the modernization of school education.…

  7. Learning to Learn in the European Reference Framework for Lifelong Learning

    ERIC Educational Resources Information Center

    Pirrie, Anne; Thoutenhoofd, Ernst D.

    2013-01-01

    This article explores the construction of learning to learn that is implicit in the document "Key Competences for Lifelong Learning--European Reference Framework" and related education policy from the European Commission. The authors argue that the hallmark of learning to learn is the development of a fluid sociality rather than the…

  8. SNS BEAM COMMISSIONING TOOLS AND EXPERIENCE

    SciTech Connect

    Shishlo, Andrei P; Galambos, John D

    2008-01-01

    The Spallation Neutron Source (SNS) successfully met the primary construction project completion milestones in April 2006. An important ingredient of this successful commissioning was the development and use of software tools. With the increasing digitalization of beam diagnostics and increasing complexity of Integrated Control Systems of large accelerators, the need for high level software tools is critical for smooth commissioning. At SNS a special Java based infrastructure called XAL was prepared for beam commissioning. XAL provides a hierarchal view of the accelerator, is data base configured, and includes a physics model of the beam. This infrastructure and individual applications development along with a historical time line of the SNS commissioning will be discussed.

  9. NUMERIC: Statistics for the Digitisation of European Cultural Heritage

    ERIC Educational Resources Information Center

    Poll, Roswitha

    2010-01-01

    Purpose: The purpose of this paper is to present results of NUMERIC, a project of the European Commission that started out to define measures and methods for assessing the current state of digitisation in Europe's cultural institutions (archives, libraries and museums). The central task of the NUMERIC project was to develop a framework for the…

  10. VIRUS early installation and commissioning

    NASA Astrophysics Data System (ADS)

    Tuttle, Sarah E.; Hill, Gary J.; Vattiat, Brian L.; Lee, Hanshin; Drory, Niv; Kelz, Andreas; Ramsey, Jason; Peterson, Trent; Noyola, Eva; DePoy, Darren L.; Marshall, Jennifer L.; Chonis, Taylor S.; Dalton, Gavin; Fabricius, Maximilian; Farrow, Daniel; Good, John M.; Haynes, Dionne M.; Indahl, Briana; Jahn, Thomas; Kriel, Hermanus; Nicklas, Harald; Montesano, Francesco; Prochaska, Travis; Allen, Richard D.; Landriau, Martin; MacQueen, Phillip J.; Roth, Martin M.; Savage, Richard; Snigula, Jan M.

    2016-08-01

    VIRUS is a massively replicated spectrograph built for HETDEX, the Hobby Eberly Telescope Dark Energy Experiment. It consists of 156 channels within 78 units fed by 34944 fibers over the 22 arcminute field of the upgraded HET. VIRUS covers a relatively narrow bandpass (350-550nm) at low resolution (R 700) to target the emission of Lyman-alpha emitters (LAEs) for HETDEX. VIRUS is a first demonstration of industrial style assembly line replication in optical astronomy. Installation and testing of VIRUS units began in November of 2015. This winter we celebrated the first on sky instrument activity of the upgraded HET, using a VIRUS unit and LRS2-R (the upgraded facility Low Resolution Spectrograph for the HET). Here we describe progress in VIRUS installation and commissioning through June 2016. We include early sky data obtained to characterize spectrograph performance and on sky performance of the newly upgraded HET. As part of the instrumentation for first science light at the HET, the IFU fed spectrographs were used to test a full range of telescope system functionality including the field calibration unit (FCU).We also use placement of strategic IFUs to map the new HET field to the fiber placement, and demonstrate actuation of the dithering mechanism key to HETDEX observations.

  11. Occurrence and characterization of plum pox virus strain D isolates from European Russia and Crimea.

    PubMed

    Chirkov, Sergei; Ivanov, Peter; Sheveleva, Anna; Kudryavtseva, Anna; Prikhodko, Yuri; Mitrofanova, Irina

    2016-02-01

    Numerous plum pox virus (PPV) strain D isolates have been found in geographically distant regions of European Russia and the Crimean peninsula on different stone fruit hosts. Phylogenetic analysis of their partial and complete genomes suggests multiple introductions of PPV-D into Russia. Distinct natural isolates from Prunus tomentosa were found to bear unique amino acid substitutions in the N-terminus of the coat protein (CP) that may contribute to the adaptation of PPV-D to this host. Serological analysis using the PPV-D-specific monoclonal antibody 4DG5 provided further evidence that mutations at positions 58 and 59 of the CP are crucial for antibody binding.

  12. Standardization and Interoperability Problems of European Electronic Tolling Service (EETS)

    NASA Astrophysics Data System (ADS)

    Nowacki, Gabriel; Mitraszewska, Izabella; Kamiński, Tomasz; Potapczuk, Włodzimierz; Kallweit, Thomas

    The paper refers to some standardization and interoperability problems of the European Electronic Toll Service (EETS) implementation in European Union. The existing EETS systems in the European Union member states are not interoperable due to many differences among them. European Commission has taken bold steps to address that issue. The first one was the 2004/52/EC Directive on the interoperability in the Community. The second one was the decision to launch Europe's own Galileo system. The third was the EC decision from 6th October 2009, based on Research Charging Interoperability (RCI) and the Common Electronic Fee Collection System for a Road Tolling European Service(CESARE) projects. Furthermore, the Motor Transport Institute researches, concerning the mentioned matters have been presented too.

  13. European comparisons between mental health services.

    PubMed

    Wahlbeck, K

    2011-03-01

    When developing accessible, affordable and effective mental health systems, exchange of data between countries is an important moving force towards better mental health care. Unfortunately, health information systems in most countries are weak in the field of mental health, and comparability of data is low. Special international data collection exercises, such as the World Health Organization (WHO) Atlas Project and the WHO Baseline Project have provided valuable insights in the state of mental health systems in countries, but such single-standing data collections are not sustainable solutions. Improvements in routine data collection are urgently needed. The European Commission has initiated major improvements to ensure harmonized and comprehensive health data collection, by introducing the European Community Health Indicators set and the European Health Interview Survey. However, both of these initiatives lack strength in the field of mental health. The neglect of the need for relevant and valid comparable data on mental health systems is in conflict with the importance of mental health for European countries and the objectives of the 'Europe 2020' strategy. The need for valid and comparable mental health services data is today addressed only by single initiatives, such as the Organisation for Economic Co-operation and Development work to establish quality indicators for mental health care. Real leadership in developing harmonized mental health data across Europe is lacking. A European Mental Health Observatory is urgently needed to lead development and implementation of monitoring of mental health and mental health service provision in Europe.

  14. European veterinary education: a bridge to quality.

    PubMed

    Fernandes, Tito H

    2005-03-01

    The aim of this review is to provide an insight into the current state of, and future changes in, veterinary education within the European Community, as well as the role of the European Association of Establishments for Veterinary Education (EAEVE) in evaluating and raising standards of education and training. It also describes the role of EAEVE in developing strategies for changes in the future. Veterinary schools have traditionally aimed at producing the omnicompetent veterinarian at graduation. Many have questioned whether this is possible, and a recent European Commission (EC) funded market survey has confirmed that this is indeed an impossible task and has identified the requirements of society within the European Union (EU) for veterinary services in the future. There is however a need to change the current 1978 European Directive. The current mechanisms which have been used by EAEVE to evaluate over 100 veterinary schools in Europe and their relationship with other systems of appraisal are described. The future of veterinary education within the context of higher education in Europe as part of the Bologna process and in relation to standards of veterinary education worldwide are discussed. Whilst the merits of standardisation of educational quality so that there can be mutual recognition of qualifications are supported, the need to preserve the strengths associated with the diversity of approaches and teaching methods is strongly advocated.

  15. Dynamic rupture simulations on complex fault zone structures with off-fault plasticity using the ADER-DG method

    NASA Astrophysics Data System (ADS)

    Wollherr, Stephanie; Gabriel, Alice-Agnes; Igel, Heiner

    2015-04-01

    In dynamic rupture models, high stress concentrations at rupture fronts have to to be accommodated by off-fault inelastic processes such as plastic deformation. As presented in (Roten et al., 2014), incorporating plastic yielding can significantly reduce earlier predictions of ground motions in the Los Angeles Basin. Further, an inelastic response of materials surrounding a fault potentially has a strong impact on surface displacement and is therefore a key aspect in understanding the triggering of tsunamis through floor uplifting. We present an implementation of off-fault-plasticity and its verification for the software package SeisSol, an arbitrary high-order derivative discontinuous Galerkin (ADER-DG) method. The software recently reached multi-petaflop/s performance on some of the largest supercomputers worldwide and was a Gordon Bell prize finalist application in 2014 (Heinecke et al., 2014). For the nonelastic calculations we impose a Drucker-Prager yield criterion in shear stress with a viscous regularization following (Andrews, 2005). It permits the smooth relaxation of high stress concentrations induced in the dynamic rupture process. We verify the implementation by comparison to the SCEC/USGS Spontaneous Rupture Code Verification Benchmarks. The results of test problem TPV13 with a 60-degree dipping normal fault show that SeisSol is in good accordance with other codes. Additionally we aim to explore the numerical characteristics of the off-fault plasticity implementation by performing convergence tests for the 2D code. The ADER-DG method is especially suited for complex geometries by using unstructured tetrahedral meshes. Local adaptation of the mesh resolution enables a fine sampling of the cohesive zone on the fault while simultaneously satisfying the dispersion requirements of wave propagation away from the fault. In this context we will investigate the influence of off-fault-plasticity on geometrically complex fault zone structures like subduction

  16. Women Appointed to State Boards and Commissions.

    ERIC Educational Resources Information Center

    Rutgers, The State Univ., New Brunswick, NJ. Center for the American Woman and Politics.

    The report analyzed the average proportions of women on 2,134 state boards and commissions in ten areas of state government. Data were collected in 1975 at the request of the Women in Power Committee of the National Commission on the Observance of International Women's Year. The ten functional areas of government were business regulation, economic…

  17. Commission on Preservation and Access Newsletter, 1995.

    ERIC Educational Resources Information Center

    Commission on Preservation and Access Newsletter, 1995

    1995-01-01

    The Commission on Preservation and Access was established to foster and support collaboration among libraries and allied organizations in order to ensure the preservation of the published and documentary records in all formats and to provide enhanced access to scholarly information. The Commission's newsletter keeps preservation and access…

  18. 16 CFR 1101.51 - Commission interpretation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Commission interpretation. 1101.51 Section 1101.51 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Retraction § 1101.51...

  19. 44 CFR 62.6 - Minimum commissions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADJUSTMENT OF CLAIMS Issuance of Policies § 62.6 Minimum commissions. (a) The earned commission which shall be paid to any property or casualty insurance agent or broker duly licensed by a state insurance regulatory authority, with respect to each policy or renewal the agent duly procures on behalf of the...

  20. Alaska Women's Commission Regional Conferences 1986.

    ERIC Educational Resources Information Center

    Callahan, Christine

    This booklet describes the work of the Alaska Women's Commission, a state agency dedicated to the achievement of equal legal, economic, social, and political status for women in Alaska. Since its inception, the Alaska Women's Commission has provided funding for regional women's conferences in rural parts of the state. The document describes four…

  1. 76 FR 27034 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Equity and Excellence Commission AGENCY: Office for Civil Rights, U.S. Department of Education. ACTION... Commission, U.S. Department of Education, 400 Maryland Avenue, SW., Washington, DC 20202....

  2. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Commission is at 888 First Street, NE., Washington, DC 20426. Regional offices are maintained at Atlanta, GA... the United States. The time and place of meetings of the Commission are announced in advance as... members or by such agents as it may designate, conduct any hearing, or other inquiry necessary...

  3. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Commission is at 888 First Street, NE., Washington, DC 20426. Regional offices are maintained at Atlanta, GA... the United States. The time and place of meetings of the Commission are announced in advance as... members or by such agents as it may designate, conduct any hearing, or other inquiry necessary...

  4. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Commission is at 888 First Street, NE., Washington, DC 20426. Regional offices are maintained at Atlanta, GA... the United States. The time and place of meetings of the Commission are announced in advance as... members or by such agents as it may designate, conduct any hearing, or other inquiry necessary...

  5. 18 CFR 35.31 - Commission review.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... determine whether the ASC set by BPA for the applicable exchange period was determined in accordance with... Commission will order that BPA amend the ASC to conform with the methodology. If the ASC is in accord with... by the Commission will be at the rate charged to BPA by the U.S. Treasury during that period,...

  6. 18 CFR 35.31 - Commission review.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... determine whether the ASC set by BPA for the applicable exchange period was determined in accordance with... Commission will order that BPA amend the ASC to conform with the methodology. If the ASC is in accord with... by the Commission will be at the rate charged to BPA by the U.S. Treasury during that period,...

  7. 18 CFR 35.31 - Commission review.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... determine whether the ASC set by BPA for the applicable exchange period was determined in accordance with... Commission will order that BPA amend the ASC to conform with the methodology. If the ASC is in accord with... by the Commission will be at the rate charged to BPA by the U.S. Treasury during that period,...

  8. 18 CFR 35.31 - Commission review.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... determine whether the ASC set by BPA for the applicable exchange period was determined in accordance with... Commission will order that BPA amend the ASC to conform with the methodology. If the ASC is in accord with... by the Commission will be at the rate charged to BPA by the U.S. Treasury during that period,...

  9. 18 CFR 35.31 - Commission review.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... determine whether the ASC set by BPA for the applicable exchange period was determined in accordance with... Commission will order that BPA amend the ASC to conform with the methodology. If the ASC is in accord with... by the Commission will be at the rate charged to BPA by the U.S. Treasury during that period,...

  10. Commission on Preservation and Access Newsletter, 1996.

    ERIC Educational Resources Information Center

    Commission on Preservation and Access Newsletter, 1996

    1996-01-01

    The Commission on Preservation and Access was established to foster and support collaboration among libraries and allied organizations in order to ensure the preservation of the published and documentary record in all formats and to provide enhanced access to scholarly information. The Commission's newsletter keeps preservation and access…

  11. 76 FR 63325 - National Indian Gaming Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ...--management fee The NOI asked whether the Commission should consider whether the definition of net revenues.... Management Contracts--Collateral Agreements The NOI asked whether the Commission should consider promulgating a regulation requiring the review and approval of collateral agreements to a management contract....

  12. CCRIS: Carnegie Commission Reports Information System.

    ERIC Educational Resources Information Center

    Lavin, Mary Jo

    The Carnegie Commission Reports Information System (CCRIS) attempts to make the findings of the 22 Commission reports (published by McGraw Hill Book Company) more readily available to the academic community. CCRIS consists of an explanatory text of 16 pages introducing the reader to a set of 1500 edge-notched McBee cards. Each card contains a…

  13. Commissioning MMS: Challenges and Lessons Learned

    NASA Technical Reports Server (NTRS)

    Wood, Paul; Gramling, Cheryl; Reiter, Jennifer; Smith, Patrick; Stone, John

    2016-01-01

    This paper discusses commissioning of NASA's Magnetospheric MultiScale (MMS) Mission. The mission includes four identical spacecraft with a large, complex set of instrumentation. The planning for and execution of commissioning for this mission is described. The paper concludes by discussing lessons learned.

  14. MCCONE COMMISSION EDUCATION RECOMMENDATIONS. PROGRESS REPORT.

    ERIC Educational Resources Information Center

    MARTYN, KENNETH A.

    THIS FOLLOWUP STUDY EXAMINES THE PROGRESS OF THE LOS ANGELES CITY AND COUNTY SCHOOLS IN IMPLEMENTING THE EDUCATIONAL RECOMMENDATIONS IN THE REPORT OF THE MCCONE COMMISSION, THE GOVERNOR'S COMMISSION ON THE LOS ANGELES RIOTS. IT PRESENTS DATA, SUPPLIED BY THE ADMINISTRATIVE STAFF OF THE SCHOOL DISTRICTS, ON DOUBLE SESSIONS AND UNUSED CLASSROOMS,…

  15. The Civil Rights Commission Must Persist

    ERIC Educational Resources Information Center

    Reynolds, Gerald A.

    2007-01-01

    Columnist George Will and others have questioned the continuing need for a federal civil rights commission, because civil rights protections have been on the books since 1964. The chairman of the Commission, Gerald Reynolds, here responds that practitioners of critical legal theory, advocates of the Akaka-Secession bill, some proponents of…

  16. Wyoming Community College Commission Annual Report, 2010

    ERIC Educational Resources Information Center

    Wyoming Community College Commission, 2010

    2010-01-01

    The Wyoming Community College Commission (WCCC) serves the system of Wyoming's seven community colleges. Wyoming's seven community colleges provide affordable, accessible and lifelong education. The Wyoming Community College Commission supports the colleges through advocacy, coordination and collaboration. In partnership with the colleges, the…

  17. Energy Shortage Contingency Plan. (California Energy Commission)

    SciTech Connect

    Not Available

    1994-03-01

    The California Energy Commission's 1993 Energy Shortage Contingency Plan is prepared in response to state legislative requirements. The statute directs the California Energy Commission to prepare and submit to the Governor and Legislature contingency plans to deal with possible shortages of electrical energy or fuel supplies to protect public health, safety and welfare.

  18. 10 CFR 2.1331 - Commission action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Commission action. 2.1331 Section 2.1331 Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Procedures for Hearings on License Transfer... opinion including its decision on the license transfer application and the reasons for the decision....

  19. 10 CFR 2.1331 - Commission action.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Commission action. 2.1331 Section 2.1331 Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Procedures for Hearings on License Transfer... opinion including its decision on the license transfer application and the reasons for the decision....

  20. 2005 Base Closure and Realignment Commission Report

    EPA Pesticide Factsheets

    The 2005 Defense Base Closure and Realignment Commission is proud to present its Final Report for your consideration. As required by law, the Commission thoroughly and objectively reviewed the domestic installation closure and realignment recommendations proposed by the Secretary of Defense on May 13, 2005.

  1. Appalachian Regional Commission Annual Report, 2001.

    ERIC Educational Resources Information Center

    Appalachian Regional Commission, Washington, DC.

    In fiscal year 2001, the Appalachian Regional Commission invested $63.6 million in 469 economic and human development (nonhighway) projects and $389.6 million in highway projects in Appalachia. The Commission launched a new initiative to promote the development of telecommunications infrastructure, especially in distressed counties. The Commission…

  2. Faculty Mentoring: What the Boyer Commission Forgot

    ERIC Educational Resources Information Center

    Wasburn, Mara H.

    2005-01-01

    In 1998, a Carnegie Foundation Commission Report criticized America's 123 research universities for failing our educational system by ignoring undergraduate education. Notably absent from the Commission's list of recommendations was mentoring research university faculty as a strategy to improve their teaching. This article discusses strategic …

  3. 76 FR 24081 - Notice of Commission Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ..., or Rhinestreet shale formations. DATES: April 21, 2011. ADDRESSES: Susquehanna River Basin Commission... the Antes, Burket, Geneseo, Mandata, Middlesex, Needmore, or Rhinestreet shale formations shall be... Marcellus or Utica shale formations that the Commission has already determined to be subject to review...

  4. Late abortion and the European convention for human rights.

    PubMed

    te Braake, T A

    1999-01-01

    National abortion laws usually do not allow abortion when a foetus is independently viable, i.e. from a gestational age of about 24 weeks. Fetal anomalies, which may be a reason to seek abortion, are sometimes detected only in an advanced stage of pregnancy. National legislatures who want to allow 'late' abortion need to account for the protection the fetus may derive from the European Convention for the protection of human rights. As yet it remains unclear to what extent the fetus can in fact derive protection from the Convention, although several national abortion laws have been tested against it by the European Commission. The significance of the reports of the Commission on the question whether national legislation allowing abortion of a viable fetus is in conflict with the Convention, is explored. It is concluded that there is no European legal standard in terms of duration of pregnancy to which national legislatures are committed.

  5. Molecular characterization of a homolog of the ferric-uptake regulator, Fur, from the marine bacterium Marinobacter algicola DG893

    PubMed Central

    Barker, Ryan A.; Tisnado, Jerrell; Lambert, Lisa A.; Gärdes, Astrid; Carrano, Mary W.; Carrano, Paul N.; Gillian, Christopher

    2016-01-01

    Full length recombinant iron regulatory protein, Fur, has been isolated and characterized from the algal-associated marine bacterium Marinobacter algicola DG893. Under nondenaturing conditions the Fur protein behaves on size exclusion chromatography as a dimer while it is monomeric under SDS PAGE conditions. ICP-MS and fluorescence quenching experiments show that Mb-Fur binds a single metal ion (Zn, Mn, or Co) per monomer. Electrophoretic mobility shift assays were used to probe the interaction of Mb-Fur with the purported Fur box in the promoter region upstream of the vibrioferrin biosynthetic operon. Interaction of Mb-Fur with a 100 bp DNA fragment containing the Fur box in the presence of 10 μM Mn, Co or Zn(II) resulted in decreased migration of DNA on a 7.5 % polyacrylamide gel. In the absence of the Fur protein or the metal, no interaction is seen. The presence of EDTA in the binding, loading or running buffers also abolished all activity demonstrating the importance of the metal in formation of the promoter-repressor complex. Based on a high degree of similarity between Mb-Fur and its homolog from Pseudomonas aeruginosa (PA) whose X-ray structure is known we developed a structural model for the former which suggested that only one of the several metal binding sites found in other Fur’s would be functional. This is consistent with the single metal binding stoichiometry we observed. Since the purported metal binding site was one that has been described as “structural” rather than “functional” in PA and yet the monometallic Mb-Fur retains DNA Fur box binding ability it reopens the question of which site is which, or if different species have adapted the sites for different purposes. PMID:25528647

  6. Molecular characterization of a homolog of the ferric-uptake regulator, Fur, from the marine bacterium Marinobacter algicola DG893.

    PubMed

    Barker, Ryan A; Tisnado, Jerrell; Lambert, Lisa A; Gärdes, Astrid; Carrano, Mary W; Carrano, Paul N; Gillian, Christopher; Carrano, Carl J

    2015-02-01

    Full length recombinant iron regulatory protein, Fur, has been isolated and characterized from the algal-associated marine bacterium Marinobacter algicola DG893. Under nondenaturing conditions the Fur protein behaves on size exclusion chromatography as a dimer while it is monomeric under SDS PAGE conditions. ICP-MS and fluorescence quenching experiments show that Mb-Fur binds a single metal ion (Zn, Mn, or Co) per monomer. Electrophoretic mobility shift assays were used to probe the interaction of Mb-Fur with the purported Fur box in the promoter region upstream of the vibrioferrin biosynthetic operon. Interaction of Mb-Fur with a 100 bp DNA fragment containing the Fur box in the presence of 10 µM Mn, Co or Zn(II) resulted in decreased migration of DNA on a 7.5% polyacrylamide gel. In the absence of the Fur protein or the metal, no interaction is seen. The presence of EDTA in the binding, loading or running buffers also abolished all activity demonstrating the importance of the metal in formation of the promoter-repressor complex. Based on a high degree of similarity between Mb-Fur and its homolog from Pseudomonas aeruginosa (PA) whose X-ray structure is known we developed a structural model for the former which suggested that only one of the several metal binding sites found in other Fur's would be functional. This is consistent with the single metal binding stoichiometry we observed. Since the purported metal binding site was one that has been described as "structural" rather than "functional" in PA and yet the monometallic Mb-Fur retains DNA Fur box binding ability it reopens the question of which site is which, or if different species have adapted the sites for different purposes.

  7. Very Bright, Very Hot and Very Long: Swift Observations of the DG CVn "Superflare" of April 23rd, 2014

    NASA Astrophysics Data System (ADS)

    Drake, Stephen Alan; Osten, Rachel A.; Page, Kim L; Kennea, Jamie A; Oates, Samantha R; Krimm, Hans A; Gehrels, Neil; Page, Mathew J; Kowalski, Adam

    2014-08-01

    On April 23rd this year, one of the 2 stars in the close visual binary dM4e system DG CVn flared to a level bright enough 300 milliCrab in the 15-150 keV band) that it triggered the Swift Burst Alert Telescope. Two minutes later, after Swift had slewed to the direction of this source, the Swift X-ray Telescope (XRT) and the Ultraviolet Optical Telescope (UVOT) commenced observing this flare. These observations continued (intermittently) for about 20 days and yielded a fascinating case history of this colossal event, the decay of which took more than a week in the UV and soft X-ray regions, and included several smaller superimposed secondary flares. The peak 0.3-10 keV luminosity observed by the XRT of 1.9e32 erg/s at the 18 pc distance of this system is 1.5 times the 'normal' combined systemic bolometric luminosity of 1.3e32 erg/s, making this event a super-bolometric flare similar to the 2008 flare of EV Lac (also detected by Swift). The BAT and XRT spectra of this flare in the first 6 minutes indicate that the emission was dominated by very hot (>>10 keV) plasma and/or a non-thermal power-law emission. This flare is arguably the longest, most X-ray luminous and hottest flare ever seen for an M dwarf in the solar neighborhood, and is reminiscent of the 9 days long flare of the RS CVn binary CF Tuc detected by ROSAT. We discuss how these exceptional characteristics may be related to the known properties of this system, specifically to its youth (30 Myr) and rapid rotation (55 km/s).

  8. A Very Bright, Very Hot, and Very Long Flaring Event from the M Dwarf Binary System DG CVn

    NASA Astrophysics Data System (ADS)

    Osten, Rachel A.; Kowalski, Adam; Drake, Stephen A.; Krimm, Hans; Page, Kim; Gazeas, Kosmas; Kennea, Jamie; Oates, Samantha; Page, Mathew; de Miguel, Enrique; Novák, Rudolf; Apeltauer, Tomas; Gehrels, Neil

    2016-12-01

    On 2014 April 23, the Swift satellite responded to a hard X-ray transient detected by its Burst Alert Telescope, which turned out to be a stellar flare from a nearby, young M dwarf binary DG CVn. We utilize observations at X-ray, UV, optical, and radio wavelengths to infer the properties of two large flares. The X-ray spectrum of the primary outburst can be described over the 0.3-100 keV bandpass by either a single very high-temperature plasma or a nonthermal thick-target bremsstrahlung model, and we rule out the nonthermal model based on energetic grounds. The temperatures were the highest seen spectroscopically in a stellar flare, at T X of 290 MK. The first event was followed by a comparably energetic event almost a day later. We constrain the photospheric area involved in each of the two flares to be >1020 cm2, and find evidence from flux ratios in the second event of contributions to the white light flare emission in addition to the usual hot, T ˜ 104 K blackbody emission seen in the impulsive phase of flares. The radiated energy in X-rays and white light reveal these events to be the two most energetic X-ray flares observed from an M dwarf, with X-ray radiated energies in the 0.3-10 keV bandpass of 4 × 1035 and 9 × 1035 erg, and optical flare energies at E V of 2.8 × 1034 and 5.2 × 1034 erg, respectively. The results presented here should be integrated into updated modeling of the astrophysical impact of large stellar flares on close-in exoplanetary atmospheres.

  9. Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard.

    PubMed

    van Vuuren, B Jansen; Bergseth, G; Mollnes, T E; Shaw, A M

    2014-01-15

    Electroluminescent assays for epitopes on the complement components C3dg, terminal complement complex (TCC) and factor B/Bb (fB/Bb) have been developed with capture and detection antibodies to produce detection limits C3dg=91±9ng/mL, TCC=3±0.1ng/mL and fB=55.7±0.1ng/mL. The assay performance was assessed against a series of zymosan and heat aggregated IgG (HAIgG) in vitro activations of complement using a calibrated activated complement serum (ACS) as calibration standard. The ACS standard was stable within 20% accuracy over a 6-month period with freeze-thaw cycles as required. Differential activation of the complement cascade was observed for TCC showing a pseudo-first order formation half-life of 3.5h after activation with zymosan. The C3dg activation fragment indicates a 10% total activation for both activation agents. The kinetic-epitope analysis for fB indicates that the capture epitope is on the fB/Bb protein fragment which can then become covered by the formation of C3bBb or C3bBbP complexes during the time course of the cascade.

  10. 33 CFR 209.50 - Mississippi River Commission: Public observation of Commission meetings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Mississippi River Commission... ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.50 Mississippi River... of the Mississippi River Commission and to open all meetings of the Mississippi River Commission...

  11. 33 CFR 209.50 - Mississippi River Commission: Public observation of Commission meetings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Mississippi River Commission... ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.50 Mississippi River... of the Mississippi River Commission and to open all meetings of the Mississippi River Commission...

  12. 33 CFR 209.50 - Mississippi River Commission: Public observation of Commission meetings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Mississippi River Commission... ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.50 Mississippi River... of the Mississippi River Commission and to open all meetings of the Mississippi River Commission...

  13. 33 CFR 209.50 - Mississippi River Commission: Public observation of Commission meetings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Mississippi River Commission... ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.50 Mississippi River... of the Mississippi River Commission and to open all meetings of the Mississippi River Commission...

  14. 33 CFR 209.50 - Mississippi River Commission: Public observation of Commission meetings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Mississippi River Commission... ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.50 Mississippi River... of the Mississippi River Commission and to open all meetings of the Mississippi River Commission...

  15. Instrumented home energy rating and commissioning

    SciTech Connect

    Wray, Craig P.; Walker, Iain S.; Sherman, Max H.

    2003-05-01

    Currently, houses do not perform optimally or even as many codes and forecasts predict, largely because they are field assembled and there is no consistent process to identify deficiencies or to correct them. Solving this problem requires field performance evaluations using appropriate and agreed upon procedures in the form of a new process called residential commissioning. The purpose of this project is to develop and document these procedures and to demonstrate the value that applying them could provide in both new and existing California houses. This project has four specific objectives: to develop metrics and diagnostics for assessing house performance, to provide information on the potential benefits of commissioning using a whole-house approach, to develop programmatic guidelines for commissioning, and to conduct outreach efforts to transfer project results to industry stakeholders. The primary outcomes from this project are the development of residential commissioning guidelines and the analytical confirmation that there are significant potential benefits associated with commissioning California houses, particularly existing ones. In addition, we have made substantial advances in understanding the accuracy and usability of diagnostics for commissioning houses. In some cases, we have been able to work with equipment manufacturers to improve these aspects of their diagnostic tools. These outcomes provide a solid foundation on which to build a residential commissioning program in California. We expect that a concerted effort will be necessary to integrate such a program with existing building industry efforts and to demonstrate its use in the field.

  16. Medical imaging at risk from European directive

    NASA Astrophysics Data System (ADS)

    Keevil, Stephen

    2009-09-01

    The recent Forum article by Denis Le Bihan ("Threats to ultra-high-field MRI" August pp16-17) is a valuable addition to the ongoing debate about the impact on magnetic resonance imaging (MRI) of the European Commission's Physical Agents (EMF) directive. When this directive was introduced in 2004, exposure limits for static magnetic fields were excluded, because it was known that guidance published by the International Commission on Non-Ionizing Radiation Protection (ICNIRP) in 1994 was being revised. It is likely that the new ICNIRP guidelines, to which Le Bihan refers, will now be incorporated into the directive. If so, this could indeed impact on ultra-highfield MRI, in which Europe has a worldleading position.

  17. 17 CFR 17.00 - Information to be furnished by futures commission merchants, clearing members and foreign brokers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and file characteristics. (1) Except as otherwise approved by the Commission or its designee, all... style options, i.e., those that can be exercised at any time during the life of the options; and “E” for European, i.e., those that can be exercised only at the end of an option's life. This field is...

  18. Joint Commission suspends 'auto' adverse decision.

    PubMed

    2010-08-01

    The Joint Commission's revision of its policy on root cause analysis puts greater attention of something that, quite frankly, some ED managers might not have been aware of. The ED manager plays an important role when events occur in the department, such as: knowing who the main Joint Commission contact is in the hospital, and making them aware of a potential adverse or sentinel event that has occurred; participating in the root cause analysis to identify what ED processes might need improvement; making sure the remedial activities recommended can be measured, so The Joint Commission can see an active attempt is being made to improve.

  19. Presidential commission investigating Challenger accident at KSC

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Views of the Presidential commission investigating the Challenger accident at Kennedy Space Center (KSC). Photos include NASA Astronaut Robert Crippen pointing out Discovery tile work in the Vehicle Assembly Building (28888); KSC Director Richard Smith points out a portion of a solid rocket booster segment to Astronaut Sally Ride and to the chairman of the Presidential Commission, William P. Rogers (28889); Rogers and other members of the Pressidential commission examines the propellent contained in a solid rocket booster segment stored at one of the KSC ordinance facilities (28890).

  20. Commission on Protecting and Reducing Government Secrecy.

    DTIC Science & Technology

    2007-11-02

    Intelligence .SPB Security Policy Board SSBI Single Scope Background Investigation Go Back to the Top Page of the Commission Report ’FAS Homepaae IGov’t Secrecy IMoynihan Commission IIIndex Search IJoin FAS 2of 2 04/03/97 18:09:33, ...Department of Defense, the Central Intelligence Agency, and the National Security Agency. Consistent with the two-year time-frame provided in the statute, the...jjIndex I Search Join FAS REPORT of the COMMISSION ON PROTECTING AND RCEfDUCING GOVERNMENT SECRECY 1997 at ammtWWI SENATE

  1. Division G Commission 42: Close Binary Stars

    NASA Astrophysics Data System (ADS)

    Richards, Mercedes T.; Pribulla, Theodor; Ribas, Ignasi; Bradstreet, David H.; Dreschsel, Horst; Maceroni, Carla; Mikolajewska, Joanna; Munari, Ulisse; Prsa, Andrej; Scharfe, Colin; Southworth, John; Trimble, Virginia

    2016-04-01

    Commission 42 began life as Photometric Double Stars in 1948 at the 7th General Assembly in Zurich, under the presidency of Zdenek Kopal. As early as 1961, then General Secretary Lukas Plaut recommended a merger between C42 and C26, Double Stars, one of the original 32 commissions going back to 1919-22 (first president Aitken, assistant director at Lick). C42 became Close Binary Stars in 1970, at the 14th GA in Brighton (the first one I attended). Table 1 shows the presidents of C42, and vice presidents, from when the office started, through the history of the Commission.

  2. Nuclear Regulatory Commission: more aggressive leadership needed

    SciTech Connect

    Staats, E.B.

    1980-01-15

    The Energy Reorganization Act of 1974 which established the Nuclear Regulatory Commission required GAO to evaluate the Commission's performance by January 18, 1980. This report responds to that requirement. GAO concluded that, although improvements have been made, the Commission's nuclear regulatory performance can be characterized best as slow, indecisive, cautious - in a word, complacent. This has largely resulted from a lack of aggressive leadership as evidenced by the Commissioners' failure to establish regulatory goals, control policymaking, and most importantly, clearly define their roles in nuclear regulation.

  3. The New European Wind Atlas

    NASA Astrophysics Data System (ADS)

    Lundtang Petersen, Erik

    2013-04-01

    The New European Wind Atlas 1. European wind resource assessment through a ERA-NET Plus project 1.1 The new EU Atlas The Commission decided earlier this year to issue an ERA-NET Plus call for the creation and publication of a new EU wind atlas. The atlas will cover Member states as well as Member states' exclusive economic zones, both onshore and offshore. It involved the launch of a single joint call for proposals by promoters of national and/or regional programmes, thereby allowing a more efficient use of existing financial resources. Therefore the funding scheme is that of ERA-NET Plus which implies that at least 5 MS shall commit at least 1 million Euros each and the Commission tops up with on third of the MS contribution. Basically it is the MS research programmes that will execute the project but an important part of the project is to create "open project development platforms" with associated protocols allowing a wider range of scientists worldwide to contribute. The project has a duration of 5 years. The decision on the new wind atlas was taken after several years of work by the European Wind Energy Technology Platform and the European Energy Research Alliances' Joint programme for Wind Energy. 2. Structure of the project The project will be structured around three areas of work, to be implemented in parallel: 2.1 Creation and publication of a European wind atlas in electronic form, which will include the underlying data and a new EU wind climate database. The database will at a minimum include: Wind resources and their associated uncertainty; Extreme wind; Turbulence characteristics; Adverse weather conditions; Predictability for short term prediction; Guidelines. 2.2 Development of dynamical downscaling methodologies and open-source models. The developed downscaling methodologies and models will be fully documented and made public available and will be used to produce overview maps of wind resources and relevant data at several heights and a horizontal

  4. Photovoltaic pilot projects in the European community

    NASA Astrophysics Data System (ADS)

    Treble, F. C.; Grassi, G.; Schnell, W.

    The paper presents proposals received for the construction of photovoltaic pilot plants as part of the Commission of the European Communities' second 4-year solar energy R and D program. The proposed plants range from 30 to 300 kWp and cover a variety of applications including rural electrification, water pumping, desalination, dairy farming, factories, hospitals, schools and vacation centers. Fifteen projects will be accepted with a total generating capacity of 1 MWp, with preference given to those projects involving the development of new techniques, components and systems.

  5. MONTH-LONG EVOLUTION OF THE D/G JUPITER IMPACT SITES FROM COMET P/SHOEMAKER-LEVY 9

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This series of snapshots, taken with NASA's Hubble Space Telescope, shows evolution of the comet P/Shoemaker-Levy 9 impact region called the D/G complex. This feature was produced by two nuclei of comet P/Shoemaker-Levy 9 that collided with Jupiter on 17 and 18 July 1994, respectively, and was later modified again by the impact of the S fragment on 21 July 1994. Upper Left: This first image was taken about 90 minutes after the G impact on 18 July 1994. Nearly all of the structure in this image was created by the impact of fragment G, although a small dark spot to the left was the remainder of small fragment D that collided one day earlier. The explosion of the nucleus in Jupiter's atmosphere created the unique ring structure, which may be analogous to a 'sonic boom' on earth. Though this structure is best seen for the G impact, it is not unique. Hubble reveals similar rings around several other fresh impact sites. They are all clear evidence for coherent outward motion of this wave phenomena. Upper right: This second image, obtained on 23 July, shows that the Jovian winds have swept the material into a striking 'curly-cue' structure. Lower left, right: The structure seen in earlier views has disappeared rapidly in the images taken on 30 July and 24 August, respectively. Almost all of the changes between the images are due to Jupiter's east-west winds that play a key role in the dispersing of the dark material. Hubble Space Telescope's high resolution will allow astronomers to continue to trace the impact debris as it is transported by the Jovian winds. This information promises to advance current understanding of the physics of Jupiter's atmosphere. These black and white images were taken in near-ultraviolet light with the Wide Field Planetary Camera 2. They have been processed to correct for the curvature of Jupiter, so that the impact region appears flat, as if the viewer were hovering directly overhead. Each image is centered on -46 degrees latitude and 28

  6. Month-long Evolution of the D/G Jupiter Impact Sites from Comet P/Shoemaker-Levy 9

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This series of snapshots, taken with NASA's Hubble Space Telescope, shows evolution of the comet P/Shoemaker-Levy 9 impact region called the D/G complex. This feature was produced by two nuclei of comet P/Shoemaker-Levy 9 that collided with Jupiter on 17 and 18 July 1994, respectively, and was later modified again by the impact of the S fragment on 21 July 1994.

    Upper Left: This first image was taken about 90 minutes after the G impact on 18 July 1994. Nearly all of the structure in this image was created by the impact of fragment G, although a small dark spot to the left was the remainder of small fragment D that collided one day earlier. The explosion of the nucleus in Jupiter's atmosphere created the unique ring structure, which may be analogous to a 'sonic boom' on Earth. Though this structure is best seen for the G impact, it is not unique. Hubble reveals similar rings around several other fresh impact sites. They are all clear evidence for coherent outward motion of this wave phenomena.

    Upper right: This second image, obtained on 23 July, shows that the Jovian winds have swept the material into a striking 'curly-cue' structure.

    Lower left, right: The structure seen in earlier views has disappeared rapidly in the images taken on 30 July and 24 August, respectively. Almost all of the changes between the images are due to Jupiter's east-west winds that play a key role in the dispersing of the dark material.

    Hubble Space Telescope's high resolution will allow astronomers to continue to trace the impact debris as it is transported by the Jovian winds. This information promises to advance current understanding of the physics of Jupiter's atmosphere.

    These black and white images were taken in near-ultraviolet light with the Wide Field Planetary Camera 2. They have been processed to correct for the curvature of Jupiter, so that the impact region appears flat, as if the viewer were hovering directly overhead. Each image is centered on -46 degrees

  7. Psychosurgery: National Commission Issues Surprisingly Favorable Report

    ERIC Educational Resources Information Center

    Culliton, Barbara J.

    1976-01-01

    Presents results of a national commission's investigation of psychosurgery. Results indicate the procedure to be effective in the cure of patients suffering from pain accompanied by depression, while avoiding the destruction caused by prefrontal lobotomies. (SL)

  8. 76 FR 55424 - CFC-50 Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    ... (CFC) to ensure its continued growth and success. The Commission is an advisory committee composed of... and effectiveness of the Combined Federal Campaign (CFC) to ensure its continued growth and success....

  9. Presidential commission investigating Challenger accident at JSC

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Views of the Presidential commission investigating the Challenger accident at Johnson Space Center (JSC). Two JSC Officials chat prior to a meeting with members of the Presidential Commission on the Space Shuttle Challenger accident, while one of the commissioners studies his notes. Left to right in the foreground are Richard H. Kohrs, Deputy Manager of the National Space Transportation System (NSTS) program office; JSC Deputy Director Robert C. Goetz and Joseph F. Sutter (28749); Two JSC Officials and two members of the Commission meet in the Executive Conference Room of JSC's Project Management Building. Left to right are Goetz; Kohrs; Sutter and Dr. Arthur B.C. Walker Jr. (28750); More meeting between NASA and the commission. Left to right are Goetz; Kohrs; Walker and Robert W. Rummel and Joseph F. Sutter (28751).

  10. 17 CFR 200.63 - Commission opinions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the Commission should state the reasons for the action taken and contain a clear showing that no... guided in his decisions by a deep regard for the integrity of the system of law which he administers....

  11. 10 CFR 110.113 - Commission action.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... available at the NRC Web site, http://www.nrc.gov, and furnished to the participants. (d) The Commission may... public interest, particularly the common defense and security; and (2) A participant establishing...

  12. Commissioning medical education: principles for best practice.

    PubMed

    Walsh, Kieran

    2016-04-01

    We need to ensure that we get value for money for our investments in medical education. Commissioning is one method of ensuring that we get value. However, like any other tool, it needs to be used properly.

  13. 10 CFR 110.40 - Commission review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Canada. (5) An export involving assistance to end uses related to isotope separation, chemical... up to 5 percent in the isotope uranium-235, and those categories of exports which the Commission...

  14. Division II: Commission 10: Solar Activity

    NASA Astrophysics Data System (ADS)

    van Driel-Gesztelyi, Lidia; Scrijver, Karel J.; Klimchuk, James A.; Charbonneau, Paul; Fletcher, Lyndsay; Hasan, S. Sirajul; Hudson, Hugh S.; Kusano, Kanya; Mandrini, Cristina H.; Peter, Hardi; Vršnak, Bojan; Yan, Yihua

    2015-08-01

    The Business Meeting of Commission 10 was held as part of the Business Meeting of Division II (Sun and Heliosphere), chaired by Valentin Martínez-Pillet, the President of the Division. The President of Commission 10 (C10; Solar activity), Lidia van Driel-Gesztelyi, took the chair for the business meeting of C10. She summarised the activities of C10 over the triennium and the election of the incoming OC.

  15. Results of the NSLS-II commissioning

    NASA Astrophysics Data System (ADS)

    Wang, Guimei; Shaftan, Timur; Willeke, Ferdinand; NSLS Team, II

    2015-04-01

    The National Synchrotron Light Source II at Brookhaven National Lab is a third-generation synchrotron radiation facility that has been commissioned in 2014. The facility is based on a 3 GeV electron storage ring, which will circulate 500 mA of beam current at 1 nm rad of horizontal emittance. The storage ring is 792 meters in circumference and will accommodate more than 60 beamlines in the final built-out. The beamline sources range from insertion-devices located in straight sections, bending magnets or three-pole-wigglers configured in multiple branches. The linac commissioning activities started in March of 2012 and was accomplished in several weeks. In Dec. 2013 the booster commissioning commenced and reached its goal in February 2014. The commissioning of the NSLS-II storage ring was successfully completed in July 2014, taking about two months in total. The storage ring is now operating at 50 mA with 3 sets of Damping Wigglers resulting in 1 nm rad of horizontal emittance. We delivered the first user light on October 23, 2014. At this point six NSLS-II project beamlines are routinely taking photons since November of 2014. In this presentation I review the NSLS-II accelerator design and our experience with getting ready for the machine start-up. In the following I focus on the commissioning results and present details, issues and advances in reaching the commissioning milestones.

  16. Building commissioning: The key to quality assurance

    SciTech Connect

    1998-05-01

    This Guide is written to aid building owners and retrofit project managers currently participating in the Rebuild America program. The Guide provides information on implementing building commissioning projects that will optimize the results of existing building equipment improvements and retrofits projects. It should be used in coordination with Rebuild America`s Community Partnership Handbook. The Handbook describes, in detail, eight important steps necessary for planning and carrying out a community-wide energy-efficiency program. In step number 7 of the Handbook, commissioning is shown to be an integral aspect of implementing a building retrofit. The commissioning process ensures that a facility is safe, efficient, comfortable, and conducive to the presumed activities for which it was constructed. Rebuild America strongly encourages its partners to incorporate commissioning into their retrofit projects. By verifying the correct installation, functioning, operation, and maintenance of equipment, the commissioning process ensures that efficiency measures will continue to deliver benefits over the long term. Although commissioning can take place after the equipment has been installed, it is more effective when it takes place over the entire equipment installation process.

  17. AstRoMap European Astrobiology Roadmap.

    PubMed

    Horneck, Gerda; Walter, Nicolas; Westall, Frances; Grenfell, John Lee; Martin, William F; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R; Rettberg, Petra; Capria, Maria Teresa

    2016-03-01

    The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems • Research Topic 2: Origins of Organic Compounds in Space • Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life • Research Topic 4: Life and Habitability • Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system.

  18. AstRoMap European Astrobiology Roadmap

    PubMed Central

    Horneck, Gerda; Westall, Frances; Grenfell, John Lee; Martin, William F.; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R.; Rettberg, Petra; Capria, Maria Teresa

    2016-01-01

    Abstract The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems• Research Topic 2: Origins of Organic Compounds in Space• Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life• Research Topic 4: Life and Habitability• Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system. Key Words: Astrobiology roadmap—Europe—Origin and evolution of life—Habitability—Life detection—Life in extreme environments. Astrobiology 16, 201–243. PMID:27003862

  19. 76 FR 7839 - Notice of Commission and Commission Staff Attendance at ISO/RTO Council and Regional State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... Energy Regulatory Commission Notice of Commission and Commission Staff Attendance at ISO/RTO Council and... of the Commission and Commission staff may attend the following ISO/RTO Council and Regional State..., RTO/ISO Performance Metrics. For more information, contact Sandra Waldstein, Office of...

  20. Working towards a European Geological Data Infrastructure

    NASA Astrophysics Data System (ADS)

    van der Krogt, Rob; Hughes, Richard; Pedersen, Mikael; Serrano, Jean-Jacques; Lee, Kathryn A.; Tulstrup, Jørgen; Robida, François

    2013-04-01

    The increasing importance of geological information for policy, regulation and business needs at European and international level has been recognized by the European Parliament and the European Commission, who have called for the development of a common European geological knowledge base. The societal relevance of geoscience data/information is clear from many current issues such as shale gas exploration (including environmental impacts), the availability of critical mineral resources in a global economy, management and security with regard to geohazards (seismic, droughts, floods, ground stability), quality of (ground-)water and soil and societal responses to the impacts of climate change. The EGDI-Scope project responds to this, aiming to prepare an implementation plan for a pan-European Geological Data Infrastructure (EGDI), under the umbrella of the FP7 e- Infrastructures program. It is envisaged that the EGDI will build on geological datasets and models currently held by the European Geological Surveys at national and regional levels, and will also provide a platform for datasets generated by the large number of relevant past, ongoing and future European projects which have geological components. With European policy makers and decision makers from (international) industry as the main target groups (followed by research communities and the general public) stakeholder involvement is imperative to the successful realization and continuity of the EGDI. With these ambitions in mind, the presentation will focus on the following issues, also based on the first results and experiences of the EGDI-Scope project that started mid-2012: • The organization of stakeholder input and commitment connected to relevant 'use cases' within different thematic domains; a number of stakeholder representatives is currently involved, but the project is open to more extensive participation; • A large number of European projects relevant for data delivery to EGDI has been reviewed

  1. European Telecommunications Conference. Strategic Planning for the 1990s

    NASA Astrophysics Data System (ADS)

    Blackburn, J. F.

    1990-06-01

    The European Telecommunications Conference Strategic Planning for the 1990s provided information to delegates and their companies on strategic planning for the European market, particularly after the advent of the European Single Market at the end of 1992. The conference objective was to examine the impact of the initiatives of the European Commission (EC) and the changing attitudes to service provision by public and private sector organizations on industry and marketing. Organized by Blenheim Online and Logica, 40 delegates attended this conference, mainly from Europe, but with a few from the U.S. The papers were designed to illuminate such questions as emerging market sectors, impact of U.S telecommunications organizations in Europe, mergers and acquisition, standards, and value-added services.

  2. Code of ethics and conduct for European nursing.

    PubMed

    Sasso, Loredana; Stievano, Alessandro; González Jurado, Máximo; Rocco, Gennaro

    2008-11-01

    A main identifying factor of professions is professionals' willingness to comply with ethical and professional standards, often defined in a code of ethics and conduct. In a period of intense nursing mobility, if the public are aware that health professionals have committed themselves to the drawing up of a code of ethics and conduct, they will have more trust in the health professional they choose, especially if this person comes from another European Member State. The Code of Ethics and Conduct for European Nursing is a programmatic document for the nursing profession constructed by the FEPI (European Federation of Nursing Regulators) according to Directive 2005/36/EC On recognition of professional qualifications , and Directive 2006/123/EC On services in the internal market, set out by the European Commission. This article describes the construction of the Code and gives an overview of some specific areas of importance. The main text of the Code is reproduced in Appendix 1.

  3. Audit of the Federal Energy Regulatory Commission`s Office of Chief Accountant

    SciTech Connect

    1995-04-07

    The Federal Energy Regulatory Commission`s (Commission) mission is to oversee America`s natural gas and oil pipeline transportation, electric utility, and hydroelectric power industries to ensure that consumers receive adequate energy supplies at just and reasonable rates. To carry out this mission, the Commission issues regulations covering the accounting, reporting, and rate-making requirements of the regulated utility companies. The Commission`s Office of Chief Accountant performs financial related audits at companies to ensure compliance with these regulations. The purpose of this audit was to evaluate the office of Chief Accountant`s audit performance. Specifically, the objectives were to determine if the most appropriate audit approach was used and if a quality assurance process was in place to ensure reports were accurate and supported by the working papers.

  4. Tuberculosis among migrant populations in the European Union and the European Economic Area

    PubMed Central

    Tillmann, Taavi; Sandgren, Andreas; Williams, Gemma; Rechel, Bernd; Ingleby, David; Noori, Teymur; Mladovsky, Philipa; McKee, Martin

    2015-01-01

    Background: Although tuberculosis (TB) incidence has been decreasing in the European Union/European Economic Area (EU/EEA) in the last decades, specific subgroups of the population, such as migrants, remain at high risk of TB. This study is based on the report ‘Key Infectious Diseases in Migrant Populations in the EU/EEA’ commissioned by The European Centre for Disease Prevention and Control. Methods: We collected, critically appraised and summarized the available evidence on the TB burden in migrants in the EU/EEA. Data were collected through: (i) a comprehensive literature review; (ii) analysis of data from The European Surveillance System (TESSy) and (iii) evidence provided by TB experts during an infectious disease workshop in 2012. Results: In 2010, of the 73 996 TB cases notified in the EU/EEA, 25% were of foreign origin. The overall decrease of TB cases observed in recent years has not been reflected in migrant populations. Foreign-born people with TB exhibit different socioeconomic and clinical characteristics than native sufferers. Conclusion: This is one of the first studies to use multiple data sources, including the largest available European database on infectious disease notifications, to assess the burden and provide a comprehensive description and analysis of specific TB features in migrants in the EU/EEA. Strengthened information about health determinants and factors for migrants’ vulnerability is needed to plan, implement and evaluate targeted TB care and control interventions for migrants in the EU/EEA. PMID:25500265

  5. 75 FR 3448 - Federal Advisory Committee; Military Leadership Diversity Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... of the Secretary Federal Advisory Committee; Military Leadership Diversity Commission AGENCY... the Military Leadership Diversity Commission (hereafter referred to as the Commission) on January 15... organizations are reminded that they may submit written statements to the Military Leadership...

  6. 39 CFR 3002.10 - The Commission and its offices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... reading room where the Commission's public records are available for inspection and copying; a library... are held on matters before the Commission. The Commission also maintains an electronic reading...

  7. 47 CFR 0.401 - Location of Commission offices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....401 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General.... (i) Documents submitted by mail to this office should be addressed to: Federal Communications... located near Columbia, Maryland. The mailing address is: Federal Communications Commission,...

  8. 47 CFR 0.401 - Location of Commission offices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....401 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General.... (i) Documents submitted by mail to this office should be addressed to: Federal Communications... located near Columbia, Maryland. The mailing address is: Federal Communications Commission,...

  9. 47 CFR 0.401 - Location of Commission offices.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....401 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General.... (i) Documents submitted by mail to this office should be addressed to: Federal Communications... located near Columbia, Maryland. The mailing address is: Federal Communications Commission,...

  10. 47 CFR 0.401 - Location of Commission offices.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....401 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General.... (i) Documents submitted by mail to this office should be addressed to: Federal Communications... located near Columbia, Maryland. The mailing address is: Federal Communications Commission,...

  11. 75 FR 7927 - National Commission on Fiscal Responsibility and Reform

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... Commission on Fiscal Responsibility and Reform By the authority vested in me as President by the Constitution... Fiscal Responsibility and Reform (Commission). Sec. 2. Membership. The Commission shall be composed of...

  12. 75 FR 68823 - National Capital Memorial Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-09

    ...-action items before the Commission: (1) Design consultation--Dwight D. Eisenhower Memorial, and (2... Planning Commission; Chairman, Commission of Fine Arts; Mayor of the District of Columbia; Architect of...

  13. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells

    PubMed Central

    Hashimoto, Kiyohiro; Sharma, Vyom; Sasanuma, Hiroyuki; Tian, Xu; Takata, Minoru; Takeda, Shunichi; Swenberg, James A.; Nakamura, Jun

    2016-01-01

    Isopropyl methanesulfonate (IPMS) is the most potent genotoxic compound among methanesulfonic acid esters. The genotoxic potential of alkyl sulfonate esters is believed to be due to their alkylating ability of the O6 position of guanine. Understanding the primary repair pathway activated in response to IPMS-induced DNA damage is important to profile the genotoxic potential of IPMS. In the present study, both chicken DT40 and human TK6 cell-based DNA damage response (DDR) assays revealed that dysfunction of the FANC pathway resulted in higher sensitivity to IPMS compared to EMS or MMS. O6-alkyl dG is primarily repaired by methyl guanine methyltransferase (MGMT), while isopropyl dG is less likely to be a substrate for MGMT. Comparison of the cytotoxic potential of IPMS and its isomer n-propyl methanesulfonate (nPMS) revealed that the isopropyl moiety avoids recognition by MGMT and leads to higher cytotoxicity. Next, the micronucleus (MN) assay showed that FANC deficiency increases the sensitivity of DT40 cells to MN induction by IPMS. Pretreatment with O6-benzyl guanine (OBG), an inhibitor of MGMT, increased the MN frequency in DT40 cells treated with nPMS, but not IPMS. Lastly, IPMS induced more double strand breaks in FANC-deficient cells compared to wild-type cells in a time-dependent manner. All together, these results suggest that IPMS-derived O6-isopropyl dG escapes recognition by MGMT, and the unrepaired DNA damage leads to double strand breaks, resulting in MN induction. FANC, therefore, plays a pivotal role in preventing MN induction and cell death caused by IPMS. PMID:27486975

  14. European auxiliary propulsion, 1972

    NASA Technical Reports Server (NTRS)

    Holcomb, L. B.

    1972-01-01

    The chemical and electric auxiliary propulsion technology of the United Kingdom, France, and West Germany is discussed in detail, and the propulsion technology achievements of Italy, India, Japan, and Russia are reviewed. A comparison is presented of Shell 405 catalyst and a European spontaneous hydrazine catalyst called CNESRO I. Finally, conclusions are drawn regarding future trends in European auxiliary propulsion technology development.

  15. Dynamic Control System Performance during Commissioning of the Space Technology 7-Disturbance Reduction System Experiment of LISA Pathfinder

    NASA Technical Reports Server (NTRS)

    Hsu, Oscar; Maghami, Peiman; O’Donnell, James R., Jr.; Ziemer, John; Romero-Wolf, Andrew

    2017-01-01

    The Space Technology-7 Disturbance Reduction System (DRS) launched aboard the European Space Agencys LISA Pathfinder spacecraft on December 3, 2015, after more than a decade in development. DRS consists of three prima-ry components: an Integrated Avionics Unit (IAU), Colloidal MicroNewton Thrusters, and Dynamic Control System (DCS) algorithms implemented on the IAU. During the portions of the mission in which the DRS was under control, the DCS was responsible for controlling the spacecraft and the free-floating test masses that were part of the LISA Test Package. The commissioning period was originally divided into two periods: before propulsion separation and after pro-pulsion separation. A recommissioning period was added after an anomaly oc-curred in the thruster system. The paper will describe the activities used to com-mission DRS, present results from the commissioning of the DCS and the re-commissioning activities performed after the thruster anomaly.

  16. Clustering Analysis of Common Tasks Undertaken by Engineering Technicians in Informatics and Manufacturing in Seven European Countries

    ERIC Educational Resources Information Center

    Papadourakis, George M.; Natsika, Christina; Magnan, Myrna; Barsics, Joseph

    2008-01-01

    VALEURTECH is a pilot project under the European Commission's Leonardo II programme. It includes 35 partners from higher education institutions and professional organizations in eight European countries and has the major objectives: of (a) setting up a homogeneous "labelling" process, such as a diploma supplement, based on a common…

  17. National Policy Brokering and the Construction of the European Education Space in England, Sweden, Finland and Scotland

    ERIC Educational Resources Information Center

    Grek, Sotiria; Lawn, Martin; Lingard, Bob; Ozga, Jenny; Rinne, Risto; Segerholm, Christina; Simola, Hannu

    2009-01-01

    This paper draws on a comparative study of the growth of data and the changing governance of education in Europe. It looks at data and the "making" of a European Education Policy Space, with a focus on "policy brokers" in translating and mediating demands for data from the European Commission. It considers the ways in which…

  18. Colon capsule endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

    PubMed

    Spada, C; Hassan, C; Galmiche, J P; Neuhaus, H; Dumonceau, J M; Adler, S; Epstein, O; Gay, G; Pennazio, M; Rex, D K; Benamouzig, R; de Franchis, R; Delvaux, M; Devière, J; Eliakim, R; Fraser, C; Hagenmuller, F; Herrerias, J M; Keuchel, M; Macrae, F; Munoz-Navas, M; Ponchon, T; Quintero, E; Riccioni, M E; Rondonotti, E; Marmo, R; Sung, J J; Tajiri, H; Toth, E; Triantafyllou, K; Van Gossum, A; Costamagna, G

    2012-05-01

    PillCam colon capsule endoscopy (CCE) is an innovative noninvasive, and painless ingestible capsule technique that allows exploration of the colon without the need for sedation and gas insufflation. Although it is already available in European and other countries, the clinical indications for CCE as well as the reporting and work-up of detected findings have not yet been standardized. The aim of this evidence-based and consensus-based guideline, commissioned by the European Society of Gastrointestinal Endoscopy (ESGE) is to furnish healthcare providers with a comprehensive framework for potential implementation of this technique in a clinical setting.

  19. Yale and the Atomic Bomb Casualty Commission.

    PubMed

    Bowers, J Z

    1983-01-01

    This is a description, based largely on personal discussions, of the contributions of men from the Yale University School of Medicine to the saga of the immediate and long-term studies on the medical effects of the atomic bombs at Hiroshima and Nagasaki. They played key roles in the immediate studies of bomb effects, in the creation of long-term studies of delayed effects, and in elevating the Atomic Bomb Casualty Commission after 1955 to a position of excellence in its studies and relations with the Japanese. The accumulation of the information presented in this paper derives from research for the preparation of the history of the Atomic Bomb Casualty Commission. In 1975, the commission was passed to Japanese leadership as the Radiation Effects Research Foundation.

  20. Commissioning of the Ground Test Accelerator RFQ

    SciTech Connect

    Johnson, K.F.; Sander, O.R.; Atkins, W.H.; Bolme, G.O.; Brown, S.; Connolly, R.; Garnett, R.; Gilpatrick, J.D.; Guy, F.W.; Ingalls, W.B.; Little, C.; Lohson, R.A.; Lloyd, S.; Neuschaefer, G.; Power, J.; Saadatmand, K.; Sandoval, D.P.; Stevens, R.R.; Vaughn, G.; Wadlinger, E.A.; Weiss, R.; Yuan, V.

    1992-01-01

    The Ground Test Accelerator (GTA) has the objective of verifying much of the technology (physics and engineering) required for producing high-brightness, high-current H{sup {minus}} beams. GTA commissioning is staged to verify the beam dynamics design of each major accelerator component as it is brought on-line. The commissioning stages are the 35 key H{sup {minus}} injector, the 2.5 MeV Radio Frequency Quadrupole (RFQ), the Intertank Matching Section (IMS), the 3.2 MeV first 2{beta}{gamma} Drift Tube Linac (DTL-1) module, the 8.7 MeV 2{beta}{gamma} DTL (modules 1--5), and the 24 MeV GTA; all 10 DTL modules. Commissioning results from the RFQ beam experiments will be presented along with comparisons to simulations.

  1. Commissioning of the Ground Test Accelerator RFQ

    SciTech Connect

    Johnson, K.F.; Sander, O.R.; Atkins, W.H.; Bolme, G.O.; Brown, S.; Connolly, R.; Garnett, R.; Gilpatrick, J.D.; Guy, F.W.; Ingalls, W.B.; Little, C.; Lohson, R.A.; Lloyd, S.; Neuschaefer, G.; Power, J.; Saadatmand, K.; Sandoval, D.P.; Stevens, R.R.; Vaughn, G.; Wadlinger, E.A.; Weiss, R.; Yuan, V.

    1992-09-01

    The Ground Test Accelerator (GTA) has the objective of verifying much of the technology (physics and engineering) required for producing high-brightness, high-current H{sup {minus}} beams. GTA commissioning is staged to verify the beam dynamics design of each major accelerator component as it is brought on-line. The commissioning stages are the 35 key H{sup {minus}} injector, the 2.5 MeV Radio Frequency Quadrupole (RFQ), the Intertank Matching Section (IMS), the 3.2 MeV first 2{beta}{gamma} Drift Tube Linac (DTL-1) module, the 8.7 MeV 2{beta}{gamma} DTL (modules 1--5), and the 24 MeV GTA; all 10 DTL modules. Commissioning results from the RFQ beam experiments will be presented along with comparisons to simulations.

  2. VINCI: the VLT Interferometer commissioning instrument

    NASA Astrophysics Data System (ADS)

    Kervella, Pierre; Coudé du Foresto, Vincent; Glindemann, Andreas; Hofmann, Reiner

    2000-07-01

    The Very Large Telescope Interferometer (VLTI) is a complex system, made of a large number of separated elements. To prepare an early successful operation, it will require a period of extensive testing and verification to ensure that the many devices involved work properly together, and can produce meaningful data. This paper describes the concept chosen for the VLTI commissioning instrument, LEONARDO da VINCI, and details its functionalities. It is a fiber based two-way beam combiner, associated with an artificial star and an alignment verification unit. The technical commissioning of the VLTI is foreseen as a stepwise process: fringes will first be obtained with the commissioning instrument in an autonomous mode (no other parts of the VLTI involved); then the VLTI telescopes and optical trains will be tested in autocollimation; finally fringes will be observed on the sky.

  3. Division G Commission 45: Stellar Classification

    NASA Astrophysics Data System (ADS)

    Gray, Richard; Soubiran, Caroline; Nordström, Birgitta; Burgasser, Adam; Gupta, Ranjan; Hanson, Margaret; Leggett, Sandy K.; Soubiran, Caroline; Singh, Harinder P.; Nordström, Birgitta

    2016-04-01

    Commission 45 is solidly anchored in the beginnings of the IAU. It evolved out of Commission 29, which was one of the original commissions and whose title and emphasis was the Spectral Classification of Stars (Transactions of the IAU, Volume I, 1922). C29 was formed with W.S. Adams (Pasadena) as president. Its first members were Miss Cannon, R.H. Curtiss, A. Fowler, A. de Gramont, M. Hamy, H.F. Newall, J.S. Plaskett, H.N. Russell, all very much part of the history of stellar spectroscopy. In the 1922 Transactions report it was recognized the Harvard System of spectral classification ``has already been adopted by international agreement. . .''

  4. European pharmacovigilance: increasingly outsourced to drug companies.

    PubMed

    2014-12-01

    New regulations reorganising pharmacovigilance at the European level were adopted in late 2010, then revised in 2012 in the wake of the Mediator (benfluorex) disaster. The European Commission's original proposals, released in 2008, would have represented a major step backwards in the protection afforded to European citizens, in particular by facilitating earlier marketing authorisations. Thanks to the mobilisation of civil society, the Members of the European Parliament have improved these proposals, supported by EU health ministers. The role of the new European Pharmacovigilance Risk Assessment Committee (PRAC) has been strengthened. Patients in every Member State have the right to report adverse drug effects directly to health authorities. EU drug regulatory agencies are required to provide greater transparency, and public access to information about adverse effects has been improved. However, one major regression persists: the central role given to pharmaceutical companies in the collection and interpretation of reports of adverse drug effects, despite their conflicts of interest. Drug companies are asked to record the adverse effect reports of which they are aware in a vast European centralised database, Eudravigilance, without going through drug regulatory agencies. Pharmaceutical companies remain responsible for producing "a scientific evaluation of the risk-benefit balance" of their drug, as part of the periodic benefit-risk assessment reports they are required to submit to drug regulatory agencies. These reports are analysed for the entire EU by two Member States (one rapporteur and one co-rapporteur), so that harmonised decisions can be taken. But these decisions are based on data preanalysed by the drug companies. In addition, the independence of the European Medicines Agency is undermined by its financial reliance on the fees paid by pharmaceutical companies in exchange for these assessments. In 2012, following France's Mediator disaster, several modest

  5. 75 FR 27981 - Codex Alimentarius Commission: Meeting of the Codex Alimentarius Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... Food Safety and Inspection Service Codex Alimentarius Commission: Meeting of the Codex Alimentarius... Session of the Codex Alimentarius Commission (CAC), which will be held in Geneva, Switzerland, July 5-9... Session of the CAC and About the Public Meeting Contact: Barbara McNiff, U.S. Codex Office,...

  6. Boys' Reading Commission 2012: A Review of Existing Research Conducted to Underpin the Commission

    ERIC Educational Resources Information Center

    Clark, Christina

    2012-01-01

    The gender gap has been a hotly debated issue, both nationally and internationally. In 2000, the then Department for Education and Schools commissioned a four-year study into raising boys' achievement. The commission worked with over 60 primary, secondary and special schools in England to identify and evaluate the strategies highlighted to be…

  7. Commissioning an Elekta Versa HD linear accelerator.

    PubMed

    Narayanasamy, Ganesh; Saenz, Daniel; Cruz, Wilbert; Ha, Chul S; Papanikolaou, Niko; Stathakis, Sotirios

    2016-01-08

    The purpose of this study is to report the dosimetric aspects of commissioning performed on an Elekta Versa HD linear accelerator (linac) with high-dose-rate flattening filter-free (FFF) photon modes and electron modes. Acceptance and commissioning was performed on the Elekta Versa HD linac with five photon energies (6 MV, 10 MV, 18 MV, 6 MV FFF, 10 MV FFF), four electron energies (6 MeV, 9MeV, 12 MeV, 15 MeV) and 160-leaf (5 mm wide) multileaf collimators (MLCs). Mechanical and dosimetric data were measured and evaluated. The measurements include percent depth doses (PDDs), in-plane and cross-plane profiles, head scatter factor (Sc), relative photon output factors (Scp), universal wedge transmission factor, MLC transmission factors, and electron cone factors. Gantry, collimator, and couch isocentricity measurements were within 1 mm, 0.7 mm, and 0.7 mm diameter, respectively. The PDDs of 6 MV FFF and 10 MV FFF beams show deeper dmax and steeper falloff with depth than the corresponding flattened beams. While flatness values of 6 MV FFF and 10 MV FFF normalized profiles were expectedly higher than the corresponding flattened beams, the symmetry values were almost identical. The cross-plane penumbra values were higher than the in-plane penumbra values for all the energies. The MLC transmission values were 0.5%, 0.6%, and 0.6% for 6 MV, 10 MV, and 18 MV photon beams, respectively. The electron PDDs, profiles, and cone factors agree well with the literature. The outcome of radiation treatment is directly related to the accuracy in the dose modeled in the treatment planning system, which is based on the commissioned data. Commissioning data provided us a valuable insight into the dosimetric characteristics of the beam. This set of commissioning data can provide comparison data to others performing Versa HD commissioning, thereby improving patient safety.

  8. Division XII: Commission 6: Astronomical Telegrams

    NASA Astrophysics Data System (ADS)

    Samus, N. N.; Yamaoka, H.; Gilmore, A. C.; Aksnes, K.; Green, D. W. E.; Marsden, B. G.; Nakano, S.; Lara, Martin; Pitjeva, Elena V.; Sphar, T.; Ticha, J.; Williams, G.

    2015-08-01

    IAU Commission 6 ``Astronomical Telegrams'' had a single business meeting during the Beijing General Assembly of the IAU. It took place on Friday, August 24, 2012. The meeting was attended by five C6 members (N. N. Samus; D. W. E. Green; S. Nakano; J. Ticha; and H. Yamaoka). Also present was Prof. F. Genova as a representative of the IAU Division B. She told the audience about the current restructuring of IAU Commissions and Divisions and consequences for the future of C6.

  9. Security role in today's Joint Commission surveys.

    PubMed

    White, Donald E

    2010-01-01

    The old saying "the more it changes, the more it is the same thing," does not apply to the Joint Commission, which has changed more than it's name, according to the author. In this article, in which he gives detailed first-hand information on today's survey experience, including the pitfalls to be expected, he reports that healthcare security's roles have been expanded. Unannounced inspections now start the previous evening, thanks to surveyor drive-bys. The Life Safety surveyor has replaced the Administrator surveyor on the Joint Commission's inspection team. Two things to be prepared for are detailed questioning about security staff competency and room contents hazards for each room.

  10. COMMISSIONING OF RHIC AT 100 GEV / NUCLEON.

    SciTech Connect

    TRBOJEVIC,D.; AHRENS,L.; BLASKIEWICZ,M.; BRENNAN,J.M.; BAI,M.; CAMERON,P.; CARDONA,J.; CONNOLLY,R.; DREES,A.; FLILLER,R.P.; ET AL

    2002-06-02

    This report describes commissioning of the Relativistic Heavy Ion Collider (RHIC) for 100 GeV/nucleon collisions at designed luminosity. To achieve these goals new systems had to be commissioned: Gamma-t transition crossing jump quadrupoles, rebucketing with the new RF storage cavities, phase lock loop feedback, betatron and crystal collimation, beta squeeze along the ramp, Siberian snake magnets for the proton polarization run, AC dipole system chromaticity measurements along the acceleration ramp, orbit correction, new ramp management system, upgraded sequencer, new data instrumentation and logger acquisition system etc.

  11. Update from the Commission on Cancer.

    PubMed

    Clive, R E

    1997-02-01

    A model for an integrated, comprehensive program for high-quality, cost-effective patient care can be found in cancer programs approved by the Commission on Cancer. A key component in assessing the effectiveness of the model is the cancer registry. Changes in the health care delivery system are behind increased demands for and use of cancer registry data. To support this shift and expanded activity, the Commission on Cancer has instituted a series of initiatives. These steps address refinements of the standards for approval, collaborative relationships, performance measurement information, new educational opportunities, and an organized communications campaign.

  12. Commissioning Simulations for the APS Upgrade Lattice

    SciTech Connect

    Sajaev, V.; Borland, M.

    2015-01-01

    A hybrid seven-bend-achromat lattice that features very strong focusing elements and a relatively small vacuum chamber has been proposed for the APS upgrade. Achieving design lattice parameters during commissioning will need to be accomplished quickly in order to minimize dark time for APS users. The paper will describe start-to-end simulation of the machine commissioning beginning from first-turn trajectory correction, progressing to orbit and lattice correction, and culminating in evaluation of the nonlinear performance of the corrected lattice

  13. An adaptive spectral/DG method for a reduced phase-space based level set approach to geometrical optics on curved elements

    NASA Astrophysics Data System (ADS)

    Cockburn, Bernardo; Kao, Chiu-Yen; Reitich, Fernando

    2014-02-01

    We present an adaptive spectral/discontinuous Galerkin (DG) method on curved elements to simulate high-frequency wavefronts within a reduced phase-space formulation of geometrical optics. Following recent work, the approach is based on the use of level sets defined by functions satisfying the Liouville equations in reduced phase-space and, in particular, it relies on the smoothness of these functions to represent them by rapidly convergent spectral expansions in the phase variables. The resulting (hyperbolic) system of equations for the coefficients in these expansions are then amenable to a high-order accurate treatment via DG approximations. In the present work, we significantly expand on the applicability and efficiency of the approach by incorporating mechanisms that allow for its use in scattering simulations and for a reduced overall computational cost. With regards to the former we demonstrate that the incorporation of curved elements is necessary to attain any kind of accuracy in calculations that involve scattering off non-flat interfaces. With regards to efficiency, on the other hand, we also show that the level-set formulation allows for a space p-adaptive scheme that under-resolves the level-set functions away from the wavefront without incurring in a loss of accuracy in the approximation of its location. As we show, these improvements enable simulations that are beyond the capabilities of previous implementations of these numerical procedures.

  14. [Human cloning in the activities of the European Union].

    PubMed

    Mik, C

    2001-01-01

    The European Union has been concerned with human cloning since the late 80. It resulted from inclusion of biotechnology into the sphere of European integration. The attitude of the European Union in the domain of human cloning was shaped, in principle in the second part of the 90. As the Community law stands at present, the European Union is not able to regulate all aspects of the cloning of human beings. It has no general power to decide in that sphere, especially, as far as bioethic aspects are concerned. The cloning of human beings in the European Union is understood as a process aiming at producing new human being, genetically identical with another live or dead human being. Thus the notion of human cloning is reduced to reproductive cloning. Three instruments are at the disposal of the European Union in the domain of human cloning. The first is prohibition of reproductive cloning as a general principle of Community law. However, that principle is not the result of judicial activity of the European Court of Justice (as general principles normally are), but the logical consequence of views formally expressed by the European Parliament, the Council of the Europe as well as the Commission. The principle was finally included in the Charter of fundamental rights of the European Union. The second instrument is an imperative prohibition of patent granting to biotechnological inventions on human reproductive cloning. Last, but not least, the Union applies a prohibition of financing scientific research connected with human cloning from the budget of the European Communities within the V Framework Programme in the field of research and technological development.

  15. The European experience.

    PubMed

    Roels, Leo; Rahmel, Axel

    2011-04-01

    This mini-review on European experiences with tackling the problem of organ shortage for transplantation was based on a literature review of predominantly European publications dealing with the issue of organ donation from deceased donors. The authors tried to identify the most significant factors that have demonstrated to impact on donation rates from deceased donors and subsequent transplant successes. These factors include legislative measures (national laws and European Directives), optimization of the donation process, use of expanded criteria donors, innovative preservation and surgical techniques, organizational efforts, and improved allocation algorithms.

  16. The European Spallation Source

    SciTech Connect

    Lindroos M.; Calaga R.; Bousson S.; Danared H.; Devanz G. et al

    2011-04-20

    In 2003 the joint European effort to design a European Spallation Source (ESS) resulted in a set of reports, and in May 2009 Lund was agreed to be the ESS site. The ESS Scandinavia office has since then worked on setting all the necessary legal and organizational matters in place so that the Design Update and construction can be started in January 2011, in collaboration with European partners. The Design Update phase is expected to end in 2012, to be followed by a construction phase, with first neutrons expected in 2018-2019.

  17. European journals on microbiology.

    PubMed

    Ronda, C; Vázquez, M

    1997-12-01

    A survey on the scientific journals dealing with microbiology published in Europe has been carried out. Eighteen European countries publish microbiological journals with the United Kingdom. Netherlands and Germany leading in number of journals on this specialty. Most of the European journals on microbiology are published bimonthly (27%), and English is the most common language used (54%). Most of these journals (86%) are included in some database, but only 36 (25%) are indexed in the six databases studied. Out of the 146 journals registered, 71 (49%), published in 11 European countries, are included in the 1995 Journal Citation Reports (ISI, Philadelphia).

  18. Enhancing the European Union’s Development Strategy in Afghanistan

    DTIC Science & Technology

    2010-06-01

    Program , National Rural Access Program (NRAP), and the Microfinance Program . Thirteen EU member states, as well as the European Commission, use the...Afghanistan, 3. 50 Figure 12. EU Lead Donors – Security Sector Reform141 The primary objective of the Swedish program in Afghanistan is poverty ...Councils could continue to utilize the National Solidarity Program to integrate community poverty reduction plans, but it could also begin to

  19. 76 FR 71449 - Reporting Line for the Commission's Ethics Counsel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... 200 Reporting Line for the Commission's Ethics Counsel AGENCY: Securities and Exchange Commission... rules to reflect that the Commission's Office of the Ethics Counsel is now a stand-alone Office of the Commission and that the head of the Office, the Ethics Counsel, reports directly to the Chairman of...

  20. 76 FR 4646 - Blue Ribbon Commission on America's Nuclear Future

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy... facsimile (202) 586- 0544; e-mail CommissionDFO@nuclear.energy.gov . Additional information will be... to CommissionDFO@nuclear.energy.gov , or post comments on the Commission Web site at...

  1. 75 FR 25850 - Blue Ribbon Commission on America's Nuclear Future

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ... Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy...- 0544; e-mail CommissionDFO@nuclear.energy.gov . Additional information may also be available at http... to CommissionDFO@nuclear.energy.gov , or post comments on the Commission Web site at...

  2. 76 FR 1608 - Blue Ribbon Commission on America's Nuclear Future

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy... and nuclear waste. The Commission is scheduled to submit a draft report to the Secretary of Energy by... to CommissionDFO@nuclear.energy.gov , or post comments on the Commission Web site at...

  3. 75 FR 3488 - Flight 93 National Memorial Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... joint Commission and Task Force meeting will consist of: 1. Opening of Meeting and Pledge of Allegiance... National Park Service Flight 93 National Memorial Advisory Commission AGENCY: National Park Service. ACTION... meeting of the Flight 93 Advisory Commission. DATES: The public meeting of the Advisory Commission will...

  4. 75 FR 17158 - Flight 93 National Memorial Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... National Park Service Flight 93 National Memorial Advisory Commission AGENCY: National Park Service..., 2010, meeting of the Flight 93 Advisory Commission. DATES: The public meeting of the Advisory Commission will be held on Saturday, May 1, 2010, from 10 a.m. to 1 p.m. (Eastern). The Commission will...

  5. 11 CFR 7.17 - Use of Commission employment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Commission Employees § 7.17 Use of Commission employment. A special Commission employee shall not use his or her Commission employment for a purpose that is, or gives the appearance of being, motivated by a... whom the employee has family, business or financial ties....

  6. 16 CFR 1000.6 - Commission decisions and records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... action, if known. (b) Other records in the custody of the Commission may be requested by e-mail (cpsc-os... Record of Commission Action. Copies of Minutes or of a Record of Commission Action may be obtained by e-mail (cpsc-os@cpsc.gov) or written request to the Secretary, Consumer Product Safety Commission,...

  7. 16 CFR 1000.6 - Commission decisions and records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... action, if known. (b) Other records in the custody of the Commission may be requested by e-mail (cpsc-os... Record of Commission Action. Copies of Minutes or of a Record of Commission Action may be obtained by e-mail (cpsc-os@cpsc.gov) or written request to the Secretary, Consumer Product Safety Commission,...

  8. 16 CFR 1000.6 - Commission decisions and records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... action, if known. (b) Other records in the custody of the Commission may be requested by e-mail (cpsc-os... Record of Commission Action. Copies of Minutes or of a Record of Commission Action may be obtained by e-mail (cpsc-os@cpsc.gov) or written request to the Secretary, Consumer Product Safety Commission,...

  9. 16 CFR 1000.6 - Commission decisions and records.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... action, if known. (b) Other records in the custody of the Commission may be requested by e-mail (cpsc-os... Record of Commission Action. Copies of Minutes or of a Record of Commission Action may be obtained by e-mail (cpsc-os@cpsc.gov) or written request to the Secretary, Consumer Product Safety Commission,...

  10. 16 CFR 1000.6 - Commission decisions and records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... action, if known. (b) Other records in the custody of the Commission may be requested by e-mail (cpsc-os... Record of Commission Action. Copies of Minutes or of a Record of Commission Action may be obtained by e-mail (cpsc-os@cpsc.gov) or written request to the Secretary, Consumer Product Safety Commission,...

  11. 47 CFR 1.1 - Proceedings before the Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Proceedings before the Commission. 1.1 Section 1.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure General § 1.1 Proceedings before the Commission. The Commission may on...

  12. 47 CFR 1.1 - Proceedings before the Commission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Proceedings before the Commission. 1.1 Section 1.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure General § 1.1 Proceedings before the Commission. The Commission may on...

  13. Arizona Commission of Indian Affairs 1986-87 Annual Report.

    ERIC Educational Resources Information Center

    Arizona Commission of Indian Affairs, Phoenix.

    This annual report includes a list of commission membership and staff; a map of state Indian reservations; a table of reservation acreages and populations; a list of commission meetings and those in attendance; a list of 1986-87 commission publications and an agency financial report. A section of "commission highlights" summarizes nine…

  14. 11 CFR 103.1 - Notification of the commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Notification of the commission. 103.1 Section 103.1 Federal Elections FEDERAL ELECTION COMMISSION GENERAL CAMPAIGN DEPOSITORIES (2 U.S.C. 432(h)) § 103.1 Notification of the commission. Each committee shall notify the Commission of the...

  15. 22 CFR 401.8 - Decision by the whole Commission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.8 Decision by the whole Commission. The whole Commission shall consider and determine...

  16. 22 CFR 401.8 - Decision by the whole Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.8 Decision by the whole Commission. The whole Commission shall consider and determine...

  17. 22 CFR 401.8 - Decision by the whole Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.8 Decision by the whole Commission. The whole Commission shall consider and determine...

  18. 22 CFR 401.8 - Decision by the whole Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.8 Decision by the whole Commission. The whole Commission shall consider and determine...

  19. 22 CFR 401.8 - Decision by the whole Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Decision by the whole Commission. 401.8 Section 401.8 Foreign Relations INTERNATIONAL JOINT COMMISSION, UNITED STATES AND CANADA RULES OF PROCEDURE General § 401.8 Decision by the whole Commission. The whole Commission shall consider and determine...

  20. 18 CFR 376.202 - Authority to move Commission offices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Authority to move... to move Commission offices. The Commission may provide for removal of its headquarters to any... Chairman, the Commission officer or employee in charge of a regional office of the Commission may move...

  1. 18 CFR 376.202 - Authority to move Commission offices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Authority to move... to move Commission offices. The Commission may provide for removal of its headquarters to any... Chairman, the Commission officer or employee in charge of a regional office of the Commission may move...

  2. 18 CFR 376.202 - Authority to move Commission offices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Authority to move... to move Commission offices. The Commission may provide for removal of its headquarters to any... Chairman, the Commission officer or employee in charge of a regional office of the Commission may move...

  3. 18 CFR 376.202 - Authority to move Commission offices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Authority to move... to move Commission offices. The Commission may provide for removal of its headquarters to any... Chairman, the Commission officer or employee in charge of a regional office of the Commission may move...

  4. 18 CFR 376.202 - Authority to move Commission offices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Authority to move... to move Commission offices. The Commission may provide for removal of its headquarters to any... Chairman, the Commission officer or employee in charge of a regional office of the Commission may move...

  5. 75 FR 52932 - Notice of Commission Meeting and Public Hearing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... Area: Tohickon-Deep Run, Tohickon- Geddes-Cabin Runs, Pine Run, and North Branch Neshaminy Creek. 10... Commission Meeting and Public Hearing on the Commission's Web site, drbc.net , ten days prior to the meeting... to allow more time for the Commission to consider them. Please check the Commission's Web site,...

  6. 28 CFR 0.124 - United States Parole Commission.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false United States Parole Commission. 0.124 Section 0.124 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE United States Parole Commission § 0.124 United States Parole Commission. The U.S. Parole Commission...

  7. 28 CFR 0.124 - United States Parole Commission.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false United States Parole Commission. 0.124 Section 0.124 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE United States Parole Commission § 0.124 United States Parole Commission. The U.S. Parole Commission...

  8. 28 CFR 0.124 - United States Parole Commission.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false United States Parole Commission. 0.124 Section 0.124 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE United States Parole Commission § 0.124 United States Parole Commission. The U.S. Parole Commission...

  9. 28 CFR 0.124 - United States Parole Commission.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false United States Parole Commission. 0.124 Section 0.124 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE United States Parole Commission § 0.124 United States Parole Commission. The U.S. Parole Commission...

  10. 28 CFR 0.124 - United States Parole Commission.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false United States Parole Commission. 0.124 Section 0.124 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE United States Parole Commission § 0.124 United States Parole Commission. The U.S. Parole Commission...

  11. 18 CFR 401.89 - Action by the Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Action by the Commission. 401.89 Section 401.89 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... to law. (b) Commission Counsel shall assist the Commission with its review of the hearing record...

  12. 18 CFR 401.89 - Action by the Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Action by the Commission. 401.89 Section 401.89 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... to law. (b) Commission Counsel shall assist the Commission with its review of the hearing record...

  13. 18 CFR 401.89 - Action by the Commission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Action by the Commission. 401.89 Section 401.89 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION... to law. (b) Commission Counsel shall assist the Commission with its review of the hearing record...

  14. 47 CFR 0.401 - Location of Commission offices.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Location of Commission offices. 0.401 Section 0... Information General § 0.401 Location of Commission offices. The Commission maintains several offices and... locations. (1) The main office of the Commission is located at 445 12th Street, SW., Washington, DC...

  15. 45 CFR 701.10 - Membership of the Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Membership of the Commission. 701.10 Section 701.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS ORGANIZATION AND FUNCTIONS OF THE COMMISSION Organization Statement § 701.10 Membership of the Commission....

  16. 45 CFR 701.10 - Membership of the Commission.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Membership of the Commission. 701.10 Section 701.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS ORGANIZATION AND FUNCTIONS OF THE COMMISSION Organization Statement § 701.10 Membership of the Commission....

  17. 45 CFR 701.10 - Membership of the Commission.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Membership of the Commission. 701.10 Section 701.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS ORGANIZATION AND FUNCTIONS OF THE COMMISSION Organization Statement § 701.10 Membership of the Commission....

  18. 45 CFR 701.10 - Membership of the Commission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Membership of the Commission. 701.10 Section 701.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS ORGANIZATION AND FUNCTIONS OF THE COMMISSION Organization Statement § 701.10 Membership of the Commission....

  19. 45 CFR 701.10 - Membership of the Commission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Membership of the Commission. 701.10 Section 701.10 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS ORGANIZATION AND FUNCTIONS OF THE COMMISSION Organization Statement § 701.10 Membership of the Commission....

  20. 76 FR 31307 - Commission of Fine Arts; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... From the Federal Register Online via the Government Publishing Office COMMISSION OF FINE ARTS Commission of Fine Arts; Notice of Meeting The next meeting of the U.S. Commission of Fine Arts is scheduled... oral statements should be addressed to Thomas Luebke, Secretary, U.S. Commission of Fine Arts, at...

  1. 17 CFR 144.1 - Service upon the Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... RESPONSE TO SUBPOENAS OR OTHER DEMANDS OF A COURT § 144.1 Service upon the Commission. (a) Subject to... service of a demand directed to the Commission or to an employee of the Commission for documentary... demand must be addressed to the Secretary of the Commission, Three Lafayette Centre, 1155 21st Street,...

  2. 16 CFR 4.15 - Commission meetings.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... announcements of meetings. For each meeting, the Commission shall announce: (i) The time, place and subject matter of the meeting, (ii) Whether the meeting will be open or closed to the public, and (iii) The name... announcement shall be made at least one week before the meeting except that where the agency...

  3. The Background of the Commission on Tests.

    ERIC Educational Resources Information Center

    Pearson, Richard; Manning, Winton H.

    This paper concerns the projected changes suggested for testing in the future by the College Entrance Examination Board (CEEB). A Commission on Tests is held desirable, the general purpose of which is to describe a comprehensive series of testing activities supporting the large-scale distribution of students among college level institutions in the…

  4. U.S. Nuclear Regulatory Commission

    MedlinePlus

    ... Reactors, gives Chris Fallon, vice president of new nuclear development at Duke Energy Florida, … more… Spotlight Strategic Plan Baffle-Former Bolts Open-Phase Electrical Issue Response to GAO Materials Licensing Audit Additional ... Plant Project Aim Commission Documents Fire Protection ...

  5. Boston Water & Sewer Commission (BWSC) | Stormwater ...

    EPA Pesticide Factsheets

    2017-04-10

    The Boston Water and Sewer Commission (BWSC) was issued National Pollutant Discharge Elimination System (NPDES) Permit MAS010001, which became effective on October 29, 1999, authorizing stormwater and allowable non-stormwater discharges from its municipal separate storm sewer system (MS4).

  6. Report of Programme Commission II (Natural Sciences).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    As the first part of the report of the Programme Commission II, a summary of discussions on plans for natural sciences and their applications is presented in this document. The two agenda items are: (1) detailed consideration of the 1973-74 draft program and budget and of the 1973-78 draft medium-term outline, and (2) desirability of adopting an…

  7. Appalachian Regional Commission: 1986 Annual Report.

    ERIC Educational Resources Information Center

    Russell, Jack, Ed.; And Others

    The Appalachian Regional Commission used its $120 million appropriation for fiscal year 1986 to create and retain jobs under the jobs and private investment program, provide basic public facilities to the worst-off Appalachian counties under the distressed counties program, and to work toward closing the gaps in the Appalachian Development Highway…

  8. 1977 Annual Report - Appalachian Regional Commission.

    ERIC Educational Resources Information Center

    Appalachian Regional Commission, Washington, DC.

    Narrative and tabular data, maps, and photographs comprise this annual report for fiscal 1977 on the Appalachian Regional Commission. Among highlights reported for the year were: completion of half the mileage in the Appalachian Development Highway system, further reducing inhabitants' isolation from jobs, schools, and markets; continued reversal…

  9. 76 FR 55059 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Equity and Excellence Commission AGENCY: Office for Civil Rights, U.S. Department of Education. ACTION... States Department of Education at 400 Maryland Avenue, SW., Washington, DC 20202, in the...

  10. Commissioning of the ATLAS Liquid Argon Calorimeters

    SciTech Connect

    Cooke, Mark S.

    2009-12-17

    A selection of ATLAS liquid argon (LAr) calorimeter commissioning studies is presented. It includes a coherent noise study, a measurement of the quality of the ionization pulse shape prediction, and energy and time reconstruction analyses with cosmic and single beam signals.

  11. Appalachian Regional Commission: 1987 Annual Report.

    ERIC Educational Resources Information Center

    Russell, Jack, Ed.; And Others

    The Appalachian Regional Commission (ARC) used its $105 million appropriation for fiscal year 1987 to support three major program areas in the 13 state region: (1) creating and retaining regional jobs; (2) assisting in construction of basic facilities, particularly water and sewer systems, in the region's 90 poorest counties; and (3) working…

  12. Commission 19: ROTATION OF THE EARTH

    NASA Astrophysics Data System (ADS)

    Brzeziński, Aleksander; Ma, Chopo; Dehant, Véronique; Defraigne, Pascale; Dickey, Jean O.; Huang, Cheng-Li; Souchay, Jean; Vondrák, Jan; Charlot, Patrick; Richter, Bernd; Schuh, Harald

    2010-05-01

    The IAU Commission 19 meeting during the XXVII IAU General Assembly in Rio de Janeiro was held on Wednesday 5 August 2009, sessions 3 (14:00-15:30) and 4 (16:00-17:30). It was attended by about 40 participants. The meeting was split into three sessions.

  13. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... for licensing and regulating nuclear facilities and materials and for conducting research in support... confirmatory research. The Commission is composed of five members, appointed by the President and confirmed by... authorized or established specifically by the Act. The Advisory Committee on Reactor Safeguards and...

  14. Wyoming Community College Commission Agency Annual Report.

    ERIC Educational Resources Information Center

    Wyoming Community Coll. Commission, Cheyenne.

    This paper reports on outcomes of community college programs monitored by the Wyoming Community College Commission (WCCC). The document covers the following WCCC objectives: (1) Study of tuition rates for the community colleges; (2) Negotiation of contracts and provision of financial support for administrative computing system components and…

  15. 19 CFR 127.34 - Auctioneer's commissions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Auctioneer's commissions. 127.34 Section 127.34 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY GENERAL ORDER, UNCLAIMED, AND ABANDONED MERCHANDISE Proceeds of Sale § 127.34...

  16. Solar Dynamics Observatory Launch and Commissioning

    NASA Technical Reports Server (NTRS)

    O'Donnell, James R., Jr.; Kristin, D.; Bourkland, L.; Hsu, Oscar C.; Liu, Kuo-Chia; Mason, Paul A. C.; Morgenstern, Wendy M.; Russo, Angela M.; Starin, Scott R.; Vess, Melissa F.

    2011-01-01

    The Solar Dynamics Observatory (SDO) was launched on February 11, 2010. Over the next three months, the spacecraft was raised from its launch orbit into its final geosynchronous orbit and its systems and instruments were tested and calibrated in preparation for its desired ten year science mission studying the Sun. A great deal of activity during this time involved the spacecraft attitude control system (ACS); testing control modes, calibrating sensors and actuators, and using the ACS to help commission the spacecraft instruments and to control the propulsion system as the spacecraft was maneuvered into its final orbit. This paper will discuss the chronology of the SDO launch and commissioning, showing the ACS analysis work performed to diagnose propellant slosh transient and attitude oscillation anomalies that were seen during commissioning, and to determine how to overcome them. The simulations and tests devised to demonstrate correct operation of all onboard ACS modes and the activities in support of instrument calibration will be discussed and the final maneuver plan performed to bring SDO on station will be shown. In addition to detailing these commissioning and anomaly resolution activities, the unique set of tests performed to characterize SDO's on-orbit jitter performance will be discussed.

  17. 77 FR 2711 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... Equity and Excellence Commission AGENCY: Office for Civil Rights, Education. ACTION: Notice of open meeting (Amended). SUMMARY: On January 5, 2012, the Office for Civil Rights published in the Federal Register (FR Doc. 2011-33800 Filed 1-4-12; 8:45 a.m.) a notice of open meeting on January 23, 2012 for...

  18. Appalachian Regional Commission: 1980 Annual Report.

    ERIC Educational Resources Information Center

    Appalachian Regional Commission, Washington, DC.

    Narrative text, tables, maps, and photographs present an overview of the Appalachian Regional Commission's (ARC) activities in fiscal year 1980, past achievements, and future goals. Major accomplishments of 1980 include: allocation of almost $13 million for 1,023 nonhighway projects; completion or construction of almost 60% of the Appalachian…

  19. NEA and the Educational Policies Commission

    ERIC Educational Resources Information Center

    Urban, Wayne

    2007-01-01

    In 1957, the year the National Education Association (NEA) celebrated its 100th anniversary, the Educational Policies Commission (EPC)--a prestigious group co-sponsored by NEA and the American Association of School Administrators--published a document titled "Higher Education in a Decade of Decision." NEA intended the report to address…

  20. 75 FR 48661 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... can increase educational opportunity by improving school funding equity. The Commission will also make recommendations for restructuring school finance systems to achieve equity in the distribution of educational resources and further student performance, especially for the students at the lower end of the...

  1. Bicentennial Commission Busy with Exciting Projects.

    ERIC Educational Resources Information Center

    Stone, Kirk

    1989-01-01

    Based on an interview with U.S. Chief Justice Warren E. Burger, this article surveys several of the projects launched by the Commission on the Bicentennial of the Constitution. These projects include: the National Historical Pictorial Map Contest; the Bicentennial School Recognition Program; the Bicentennial Educational Grant Program; and the…

  2. 75 FR 48662 - Equity and Excellence Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Equity and Excellence Commission AGENCY: Office for Civil Rights, U.S. Department of Education. ACTION... Education (Secretary) invites interested parties to submit nominations for individuals to serve on...

  3. 76 FR 72452 - CFC-50 Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... Doc No: 2011-30240] OFFICE OF PERSONNEL MANAGEMENT CFC-50 Commission AGENCY: Office of Personnel... advise the Director of the U.S. Office of Personnel Management (OPM) on strengthening the integrity, the... Personnel Management, Theodore Roosevelt Executive Conference Room, 5th Floor, Theodore Roosevelt...

  4. 77 FR 77247 - Reestablishment of Advisory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... From the Federal Register Online via the Government Publishing Office ] Vol. 77 Monday, No. 250 December 31, 2012 Part IV The President Executive Order 13634--Reestablishment of Advisory Commission #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 77 , No. 250 / Monday, December 31, 2012 / Presidential Documents#0;#0; #0; #0;Title 3--...

  5. Report of the Commission on Quantum Quality.

    ERIC Educational Resources Information Center

    Thor, Linda; And Others

    The Commission on Quantum Quality was established by the Maricopa County Community College District (MCCCD) in February, 1992, to investigate total quality management (TQM) programs in community colleges, universities, the government sector, and business and industry in order to recommend an appropriate program for MCCCD. To gather information,…

  6. Mississippi Library Commission Data Network Specifications.

    ERIC Educational Resources Information Center

    Evans Associates, Thiensville, WI.

    This document provides a detailed design for the data portion of the Mississippi Library Commission (MLC) public library network. The data network is based on Frame Relay technology, and would provide more functionality at a higher speed than a previously considered dial-in network could. The document is divided into 16 sections: (1) Introduction;…

  7. European PTTI report

    NASA Technical Reports Server (NTRS)

    Cordara, Franco; Grimaldi, Sabrina; Leschiutta, Sigfrido

    1994-01-01

    Time and frequency metrology in Europe presents some peculiar features in its three main components: research on clocks, comparisons and dissemination methods, and dissemination services. Apart from the usual activities of the national metrological laboratories, an increasing number of cooperation between the European countries are promoted inside some European organizations, such as the ECC, EFTA, EUROMET, and WECC. Cooperation between these organizations is covered. The present, evolving situation will be further influenced by the recent political changes in Eastern Europe.

  8. Potential Benefits of Commissioning California Homes

    SciTech Connect

    Matson, Nance; Wray, Craig; Walker, Iain; Sherman, Max

    2002-01-01

    Commissioning California's houses can result in better performing systems and houses. In turn, this will result in more efficient use of energy, carbon emission reductions, and improved occupant comfort. In particular, commissioning houses can save a significant amount of HVAC-related energy (15 to 30% in existing houses, 10 to 20% in new conventional houses, and up to 8% in advanced energy efficiency houses). The process that we considered includes corrective measures that could be implemented together during construction or during a single site visit (e.g., air tightening, duct sealing, and refrigerant and air handler airflow corrections in a new or existing house). Taking advantage of additional, more complex opportunities (e.g., installing new windows in an existing house, replacing the heating and air conditioning system in a new or existing house) can result in additional HVAC-related energy savings (60 to 75% in existing houses, and 50 to 60% in new conventional houses). The commissioning-related system and house performance improvements and energy savings translate to additional benefits throughout California and beyond. By applying commissioning principles to their work, the building community (builders and contractors) benefit from reduced callbacks and lower warranty costs. HERS raters and inspectors will have access to an expanded market sector. As the commissioning process rectifies construction defects and code problems, building code officials benefit from better compliance with codes. The utilities benefit from reduced peak demand, which can translate into lower energy acquisition costs. As houses perform closer to expectations, governmental bodies (e.g., the California Energy Commission and the Air Resources Board) benefit from greater assurance that actual energy consumption and carbon emissions are closer to the levels mandated in codes and standards, resulting in better achievement of state energy conservation and environmental goals. California

  9. The European Citizens' Stop Vivisection Initiative and the revision of Directive.

    PubMed

    Menache, Andre

    2016-09-01

    Animal experimentation is presented to the public as an ongoing debate between research scientists on one hand, and the animal protection community on the other. An opportunity to break out of this mindset presented itself in the form of a European Citizens' Initiative, Stop Vivisection, which challenged Directive 2010/63/EU of the European Parliament and of the Council on the protection of animals for scientific purposes. The manifesto of the initiative called upon the European Commission to replace the existing Directive with a new proposal that does away with animal experimentation, and instead makes compulsory the use of human data as a predictive modality for the study of human diseases and responses to drugs. Although the Initiative succeeded in gathering the required one million signatures, the European Commission ultimately rejected the proposal. However, some of the lessons learned from the Initiative may well be relevant to the revision of Directive 2010/63/EU, due to take place by 2017.

  10. Review of recommendations on cervical cancer screening in the European Union.

    PubMed

    Patnick, J

    2003-08-01

    In 2000 the European Commission Advisory Committee on Cancer Prevention published a position paper on cancer screening with recommendations. This followed working party deliberations in 1998 and conference discussion in 1999. Scientific advances, particularly in knowledge about the relationship of HPV and cervical cancer and political developments with the enlargement of the European Union, mean that the position paper and recommendations may shortly need revising in the light of changed circumstances.

  11. Role of α-Subunit VISIT-DG Sequence Residues Ser-347 and Gly-351 in the Catalytic Sites of Escherichia coli ATP Synthase*

    PubMed Central

    Li, Wenzong; Brudecki, Laura E.; Senior, Alan E.; Ahmad, Zulfiqar

    2009-01-01

    This paper describes the role of α-subunit VISIT-DG sequence residues αSer-347 and αGly-351 in catalytic sites of Escherichia coli F1Fo ATP synthase. X-ray structures show the very highly conserved α-subunit VISIT-DG sequence in close proximity to the conserved phosphate-binding residues αArg-376, βArg-182, βLys-155, and βArg-246 in the phosphate-binding subdomain. Mutations αS347Q and αG351Q caused loss of oxidative phosphorylation and reduced ATPase activity of F1Fo in membranes by 100- and 150-fold, respectively, whereas αS347A mutation showed only a 13-fold loss of activity and also retained some oxidative phosphorylation activity. The ATPase of αS347Q mutant was not inhibited, and the αS347A mutant was slightly inhibited by MgADP-azide, MgADP-fluoroaluminate, or MgADP-fluoroscandium, in contrast to wild type and αG351Q mutant. Whereas 7-chloro-4-nitrobenzo-2-oxa-1, 3-diazole (NBD-Cl) inhibited wild type and αG351Q mutant ATPase essentially completely, ATPase in αS347A or αS347Q mutant was inhibited maximally by ∼80–90%, although reaction still occurred at residue βTyr-297, proximal to the α-subunit VISIT-DG sequence, near the phosphate-binding pocket. Inhibition characteristics supported the conclusion that NBD-Cl reacts inβE (empty) catalytic sites, as shown previously by x-ray structure analysis. Phosphate protected against NBD-Cl inhibition in wild type and αG351Q mutant but not in αS347Q or αS347A mutant. The results demonstrate that αSer-347 is an additional residue involved in phosphate-binding and transition state stabilization in ATP synthase catalytic sites. In contrast, αGly-351, although strongly conserved and clearly important for function, appears not to play a direct role. PMID:19240022

  12. Curriculum for Commissioning Energy Efficient Buildings

    SciTech Connect

    Webster, Lia

    2012-12-27

    In July 2010, the U.S. Department of Energy (DOE) awarded funding to PECI to develop training curriculum in commercial energy auditing and building commissioning. This program was created in response to the high demand for auditing and commissioning services in the U.S. commercial buildings market and to bridge gaps and barriers in existing training programs. Obstacles addressed included: lack of focus on entry level candidates; prohibitive cost and time required for training; lack of hands-on training; trainings that focus on certifications & process overviews; and lack of comprehensive training. PECI organized several other industry players to create a co-funded project sponsored by DOE, PECI, New York State Energy and Research Development Authority (NYSERDA), California Energy Commission (CEC), Northwest Energy Efficiency Alliance (NEEA) and California Commissioning Collaborative (CCC). After awarded, PECI teamed with another DOE awardee, New Jersey Institute of Technology (NJIT), to work collaboratively to create one comprehensive program featuring two training tracks. NJIT’s Center for Building Knowledge is a research and training institute affiliated with the College of Architecture and Design, and provided e-learning and video enhancements. This project designed and developed two training programs with a comprehensive, energy-focused curriculum to prepare new entrants to become energy auditors or commissioning authorities (CxAs). The following are the key elements of the developed trainings, which is depicted graphically in Figure 1: • Online classes are self-paced, and can be completed anywhere, any time • Commissioning Authority track includes 3 online modules made up of 24 courses delivered in 104 individual lessons, followed by a 40 hour hands-on lab. Total time required is between 75 and 100 hours, depending on the pace of the independent learner. • Energy Auditor track includes 3 online modules made up of 18 courses delivered in 72 individual

  13. Commissioning and periodic tests of the Esteya(®) electronic brachytherapy system.

    PubMed

    Candela-Juan, Cristian; Niatsetski, Yury; Ouhib, Zoubir; Ballester, Facundo; Vijande, Javier; Perez-Calatayud, Jose

    2015-04-01

    A new electronic brachytherapy unit from Elekta, called Esteya(®), has recently been introduced to the market. As a part of the standards in radiation oncology, an acceptance testing and commissioning must be performed prior to treatment of the first patient. In addition, a quality assurance program should be implemented. A complete commissioning and periodic testing of the Esteya(®) device using the American Association of Physicists in Medicine (AAPM), Groupe Européen de Curiethérapie and the European Society for Radiotherapy & Oncology (GEC-ESTRO) guidelines for linacs and brachytherapy units as well as our personal experience is described in this paper. In addition to the methodology, recommendations on equipment required for each test are provided, taking into consideration their availability and traceability of the detectors. Finally, tolerance levels for all the tests are provided, and a specific frequency for each test is suggested.

  14. Commissioning and periodic tests of the Esteya® electronic brachytherapy system

    PubMed Central

    Niatsetski, Yury; Ouhib, Zoubir; Ballester, Facundo; Vijande, Javier; Perez-Calatayud, Jose

    2015-01-01

    A new electronic brachytherapy unit from Elekta, called Esteya®, has recently been introduced to the market. As a part of the standards in radiation oncology, an acceptance testing and commissioning must be performed prior to treatment of the first patient. In addition, a quality assurance program should be implemented. A complete commissioning and periodic testing of the Esteya® device using the American Association of Physicists in Medicine (AAPM), Groupe Européen de Curiethérapie and the European Society for Radiotherapy & Oncology (GEC-ESTRO) guidelines for linacs and brachytherapy units as well as our personal experience is described in this paper. In addition to the methodology, recommendations on equipment required for each test are provided, taking into consideration their availability and traceability of the detectors. Finally, tolerance levels for all the tests are provided, and a specific frequency for each test is suggested. PMID:26034501

  15. Commissioning of an electrostatic precipitator burning refinary residue

    SciTech Connect

    Mayer-Schwinning, G.; Varga, A.

    1996-12-31

    The Dunamenti Power Plant is the largest Heavy Fuel Oil (HFO) fired power plant in Hungary with an annual oil consumption of approximately 1 x 10{sup 6} m.t./a. The sulfur content of this oil is rather high (S = 2 - 3 %) and it also contains heavy metals in a significant amount. These pollutants in the flue gas impair the air quality in the town of Szazhalombatta, situated next to the refinery. The number of children suffering from respiratory disorders in this town is higher than the national average. The power plant management has decided to build an ESP for its 6 x 215 MW units, partly as a result of pressure exerted by the local authority and partly because of the new Environment Act under preparation that takes account of the European emission standards. The ESP contract was awarded to LURGI GmbH, primarily because LURGI had a reference site firing HFO with very high sulfur content. The contract was signed in March 1994 and commissioning was already started in December 1994. This paper describes the ESP installed at the Dunamenti Power Plant and the experiences gained with dosing ammonium and other additives. It will also discuss the utilization of the dust.

  16. North American Commission on Stratigraphic Nomenclature Note 66: records of Stratigraphic Commission, 2003-2013

    USGS Publications Warehouse

    Easton, Robert M.; Catuneanu, Octavian; Donovan, Art D.; Fluegeman, Richard H.; Hamblin, A.P.; Harper, Howard; Lasca, Norman P.; Morrow, Jared R.; Orndorff, Randall C.; Sadler, Peter; Scott, Robert W.; Tew, Berry H.

    2014-01-01

    Note 66 summarizes activities of the North American Commission on Stratigraphic Nomenclature (NACSN) from November 2003 to October 2013 and is condensed from the minutes of the NACSN’s 58th to 68th annual meetings1. The purposes of the Commission are to develop statements of stratigraphic principles,recommend procedures applicable to the classification and nomenclature of stratigraphic and related units, review problems in classifying and naming stratigraphic and related units, and formulate expressions of judgment on these matters.

  17. New perspectives for European climate services: HORIZON2020

    NASA Astrophysics Data System (ADS)

    Bruning, Claus; Tilche, Andrea

    2014-05-01

    The developing of new end-to-end climate services was one of the core priorities of 7th Framework for Research and Technological Development of the European Commission and will become one of the key strategic priorities of Societal Challenge 5 of HORIZON2020 (the new EU Framework Programme for Research and Innovation 2014-2020). Results should increase the competitiveness of European businesses, and the ability of regional and national authorities to make effective decisions in climate-sensitive sectors. In parallel, the production of new tailored climate information should strengthen the resilience of the European society to climate change. In this perspective the strategy to support and foster the underpinning science for climate services in HORIZON2020 will be presented.

  18. The European Union Committee of Experts on Rare Diseases: three productive years at the service of the rare disease community.

    PubMed

    Aymé, Ségolène; Rodwell, Charlotte

    2014-02-28

    The European Union Committee of Experts on Rare Diseases was entrusted with aiding the European Commission in a number of tasks, ranging from the monitoring of initiatives, to recommending improvements and actions to be pursued in the future, in addition to helping strengthen liaison at both European and International levels in the field of rare diseases. The three-year mandate of the EUCERD drew to a close in July 2013 with an impressive record. The EUCERD has laid down the foundations for future work so as to continue to advance in the key areas that have been identified as of interest for the rare disease community at large: centres of expertise, European Reference Networks, patient registries and databases, newborn screening, and indicators for national rare disease plans/strategies. The work of the Committee should now be continued by the newly formed European Commission Expert Group on Rare Diseases.

  19. Division V: Commission 42: Close Binaries

    NASA Astrophysics Data System (ADS)

    Ribas, Ignasi; Richards, Mercedes T.; Rucinski, Slavek; Bradstreet, David H.; Harmanec, Petr; Kaluzny, Janusz; Mikolajewska, Joanna; Munari, Ulisse; Niarchos, Panagiotis; Olah, Katalin; Pribulla, Theodor; Scarfe, Colin D.; Torres, Guillermo

    2015-08-01

    Commission 42 (C42) co-organized, together with Commission 27 (C27) and Division V (Div V) as a whole, a full day of science and business sessions that were held on 24 August 2012. The program included time slots for discussion of business matters related to Div V, C27 and C42, and two sessions of 2 hours each devoted to science talks of interest to both C42 and C27. In addition, we had a joint session between Div IV and Div V motivated by the proposal to reformulate the division structure of the IAU and the possible merger of the two divisions into a new Div G. The current report gives an account of the matters discussed during the business session of C42.

  20. A History of the Atomic Energy Commission

    DOE R&D Accomplishments Database

    Buck, Alice L.

    1983-07-01

    This pamphlet traces the history of the US Atomic Energy Commission's twenty-eight year stewardship of the Nation's nuclear energy program, from the signing of the Atomic Energy Act on August 1, 1946 to the signing of the Energy Reorganization Act on October 11, 1974. The Commission's early concentration on the military atom produced sophisticated nuclear weapons for the Nation's defense and made possible the creation of a fleet of nuclear submarines and surface ships. Extensive research in the nuclear sciences resulted in the widespread application of nuclear technology for scientific, medical and industrial purposes, while the passage of the Atomic Energy Act of 1954 made possible the development of a nuclear industry, and enabled the United States to share the new technology with other nations.

  1. Commissioning of the PRIOR proton microscope

    DOE PAGES

    Varentsov, D.; Antonov, O.; Bakhmutova, A.; ...

    2016-02-18

    Recently, a new high energy proton microscopy facility PRIOR (Proton Microscope for FAIR Facility for Anti-proton and Ion Research) has been designed, constructed, and successfully commissioned at GSI Helmholtzzentrum für Schwerionenforschung (Darmstadt, Germany). As a result of the experiments with 3.5–4.5 GeV proton beams delivered by the heavy ion synchrotron SIS-18 of GSI, 30 μm spatial and 10 ns temporal resolutions of the proton microscope have been demonstrated. A new pulsed power setup for studying properties of matter under extremes has been developed for the dynamic commissioning of the PRIOR facility. This study describes the PRIOR setup as well asmore » the results of the first static and dynamic protonradiography experiments performed at GSI.« less

  2. NIF Commissioning and Initial Performance Results

    SciTech Connect

    Van Wonterghem, B M; Burkhart, S C; Haynam, C A; Manes, K R; Marshall, C D; Murray, J E; Spaeth, M L; Speck, D R; Sutton, S B; Wegner, P J

    2003-12-19

    The National Ignition Facility at LLNL recently commissioned the first set of four beam lines into the target chamber. This effort, also called NIF Early Light, demonstrated the entire laser system architecture from master oscillator through target and initial X-ray diagnostics. This paper describes the detailed commissioning and installation steps for one of NIF's 48 beam quads. Using a dedicated single beam line Precision Diagnostic System, performance was explored over the entire power versus energy space from 6.4 TW/beam for sub-nanosecond pulses to 25 kJ/beam for 23 ns pulses at 1 {omega}. NEL also demonstrated record single beam line frequency converted Nd:Glass laser energies of 11.3 kJ at 2 {omega} and 10.4 kJ at 3{omega}.

  3. Nuclear Regulatory Commission Information Digest, 1991 edition

    SciTech Connect

    Olive, K L

    1991-03-01

    The Nuclear Regulatory Commission Information Digest provides a summary of information about the US Nuclear Regulatory Commission (NRC), NRC's regulatory responsibilities, and the areas NRC licenses. This digest is a compilation of NRC-related data and is designed to provide a quick reference to major facts about the agency and the industry it regulates. In general, the data cover 1975 through 1990, with exceptions noted. For operating US commercial nuclear power reactors, information on generating capacity and average capacity factor is obtained from Monthly Operating Reports submitted to the NRC directly by the licensee. This information is reviewed for consistency only. No independent validation and/or verification is performed by the NRC. For detailed and complete information about tables and figures, refer to the source publications. This digest is published annually for the general use of the NRC staff and is available to the public. 30 figs., 12 tabs.

  4. Status of the SPIRAL2 injector commissioning

    SciTech Connect

    Thuillier, T. Angot, J.; Jacob, J.; Lamy, T.; Sole, P. [LPSC, Université Grenoble Alpes, CNRS Barué, C.; Bertrand, P.; Canet, C.; Ferdinand, R.; Flambard, J.-L.; Jardin, P.; Lemagnen, F.; Maunoury, L.; Osmond, B. [GANIL, CNRS Biarrotte, J. L. [IPN Orsay, Université Paris Sud, CNRS Denis, J.-F.; Roger, A.; Touzery, R.; Tuske, O.; Uriot, D. [Irfu, CEA Saclay, DSM and others

    2016-02-15

    The SPIRAL2 injector, installed in its tunnel, is currently under commissioning at GANIL, Caen, France. The injector is composed of two low energy beam transport lines: one is dedicated to the light ion beam production, the other to the heavy ions. The first light ion beam, created by a 2.45 GHz electron cyclotron resonance ion source, has been successfully produced in December 2014. The first beam of the PHOENIX V2 18 GHz heavy ion source was analyzed on 10 July 2015. A status of the SPIRAL2 injector commissioning is given. An upgrade of the heavy ion source, named PHOENIX V3 aimed to replace the V2, is presented. The new version features a doubled plasma chamber volume and the high charge state beam intensity is expected to increase by a factor of 1.5 to 2 up to the mass ∼50. A status of its assembly is proposed.

  5. Status of the SPIRAL2 injector commissioning.

    PubMed

    Thuillier, T; Angot, J; Barué, C; Bertrand, P; Biarrotte, J L; Canet, C; Denis, J-F; Ferdinand, R; Flambard, J-L; Jacob, J; Jardin, P; Lamy, T; Lemagnen, F; Maunoury, L; Osmond, B; Peaucelle, C; Roger, A; Sole, P; Touzery, R; Tuske, O; Uriot, D

    2016-02-01

    The SPIRAL2 injector, installed in its tunnel, is currently under commissioning at GANIL, Caen, France. The injector is composed of two low energy beam transport lines: one is dedicated to the light ion beam production, the other to the heavy ions. The first light ion beam, created by a 2.45 GHz electron cyclotron resonance ion source, has been successfully produced in December 2014. The first beam of the PHOENIX V2 18 GHz heavy ion source was analyzed on 10 July 2015. A status of the SPIRAL2 injector commissioning is given. An upgrade of the heavy ion source, named PHOENIX V3 aimed to replace the V2, is presented. The new version features a doubled plasma chamber volume and the high charge state beam intensity is expected to increase by a factor of 1.5 to 2 up to the mass ∼50. A status of its assembly is proposed.

  6. Commissioning of the PRIOR proton microscope

    SciTech Connect

    Varentsov, D.; Antonov, O.; Bakhmutova, A.; Barnes, C. W.; Bogdanov, A.; Danly, C. R.; Efimov, S.; Endres, M.; Fertman, A.; Golubev, A. A.; Hoffmann, D. H. H.; Ionita, B.; Kantsyrev, A.; Krasik, Ya. E.; Lang, P. M.; Lomonosov, I.; Mariam, F. G.; Markov, N.; Mintsev, V. B.; Nikolaev, D.; Panyushkin, V.; Rodionova, M.; Schanz, M.; Schoenberg, K.; Semennikov, A.; Shestov, L.; Skachkov, V. S.; Turtikov, V.; Udrea, S.; Vasylyev, O.; Weyrich, K.; Wilde, C.; Zubareva, A.; Merrill, F. E.

    2016-02-18

    Recently, a new high energy proton microscopy facility PRIOR (Proton Microscope for FAIR Facility for Anti-proton and Ion Research) has been designed, constructed, and successfully commissioned at GSI Helmholtzzentrum für Schwerionenforschung (Darmstadt, Germany). As a result of the experiments with 3.5–4.5 GeV proton beams delivered by the heavy ion synchrotron SIS-18 of GSI, 30 μm spatial and 10 ns temporal resolutions of the proton microscope have been demonstrated. A new pulsed power setup for studying properties of matter under extremes has been developed for the dynamic commissioning of the PRIOR facility. This study describes the PRIOR setup as well as the results of the first static and dynamic protonradiography experiments performed at GSI.

  7. Commissioning Results of the LCLS Injector

    SciTech Connect

    Dowell, D.H.; Akre, R.; Ding, Y.; Emma, P.; Frisch, J.; Gilevich, S.; Hays, G.; Hering, Ph.; Huang, Z.; Iverson, R.; Limborg-Deprey, C.; Loos, H.; Miahnahri, A.; Schmerge, J.; Turner, J.; Welch, J.; White, W.; Wu, J.; Frohlich, L.; Limberg, T.; Prat, E.; /DESY

    2007-11-16

    The Linac Coherent Light Source (LCLS) is a SASE xray Free-Electron Laser (FEL) project presently under construction at SLAC. The injector section, from drive-laser and RF photocathode gun through first bunch compressor chicane, was installed in fall 2006. Initial system commissioning with an electron beam has recently been completed. The second phase of construction, including second bunch compressor and full linac, is planned for 2008. In this paper, we report experimental results and experience gained during the first phase of machine commissioning. This includes the cathode, drive laser, RF photocathode gun, linac booster section, S-band and X-band RF systems, first bunch compressor, and the various beam diagnostics.

  8. Initial Commissioning Experience With the LCLS Injector

    SciTech Connect

    Akre, R.; Castro, J.; Ding, Y.; Dowell, D.H.; Emma, P.; Frisch, J.; Gilevich, A.; Hays, G.; Hering, P.; Huang, Z.; Iverson, R.; Krejcik, P.; Limborg-Deprey, C.; Loos, H.; Miahnahri, A.; Rivetta, C.; Saleski, M.; Schmerge, J.F.; Schultz, D.; Turner, J.; Welch, J.; /SLAC /DESY

    2007-11-02

    The Linac Coherent Light Source (LCLS) is a SASE xray Free-Electron Laser (FEL) project presently under construction at SLAC [1]. The injector section, from drive-laser and RF photocathode gun through first bunch compressor chicane, was installed in fall 2006. Initial system commissioning with an electron beam is taking place during the spring and summer of 2007. The second phase of construction, including second bunch compressor and full linac, will begin later, in the fall of 2007. We report here on experience gained during the first phase of machine commissioning, including RF photocathode gun, linac booster section, S-band and X-band RF systems, first bunch compressor, and the various beam diagnostics.

  9. Status of the SPIRAL2 injector commissioning

    NASA Astrophysics Data System (ADS)

    Thuillier, T.; Angot, J.; Barué, C.; Bertrand, P.; Biarrotte, J. L.; Canet, C.; Denis, J.-F.; Ferdinand, R.; Flambard, J.-L.; Jacob, J.; Jardin, P.; Lamy, T.; Lemagnen, F.; Maunoury, L.; Osmond, B.; Peaucelle, C.; Roger, A.; Sole, P.; Touzery, R.; Tuske, O.; Uriot, D.

    2016-02-01

    The SPIRAL2 injector, installed in its tunnel, is currently under commissioning at GANIL, Caen, France. The injector is composed of two low energy beam transport lines: one is dedicated to the light ion beam production, the other to the heavy ions. The first light ion beam, created by a 2.45 GHz electron cyclotron resonance ion source, has been successfully produced in December 2014. The first beam of the PHOENIX V2 18 GHz heavy ion source was analyzed on 10 July 2015. A status of the SPIRAL2 injector commissioning is given. An upgrade of the heavy ion source, named PHOENIX V3 aimed to replace the V2, is presented. The new version features a doubled plasma chamber volume and the high charge state beam intensity is expected to increase by a factor of 1.5 to 2 up to the mass ˜50. A status of its assembly is proposed.

  10. The California Debris Commission: A History

    DTIC Science & Technology

    1981-01-01

    Secretary Division with headquarters in Salt Lake City. Major E.H. Ropes (General Order No. 40, Office of Chief of Engi- 1929 Lieutenant Colonel J...Franklin Bell, President neers, dated October 26, 1942) General Warren Major E.H. Ropes , Secretary to July 31, 1928 T. Hannum became Division Engineer...office of the Pacific Major E.H. Ropes , member Division was established at the pre-existing Until September 11, 1929, the Commission consist- South

  11. Indexes to Nuclear Regulatory Commission Issuances

    SciTech Connect

    1996-12-31

    Digests and indexes for issuances of the Commission (CLI), the Atomic Safety and licensing Board Panel (LBP), the Administrative Law Judges (ALJ) the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM) are presented in this document. These digests and indexes are intended to serve as a guide to the issuances. Information elements are displayed in one or more of five separate formats arranged as follows: Case Name Index; Headers and Digests; Legal Citations Index; Subject Index; and Facility Index.

  12. Optimal Siting and Sizing of Multiple DG Units for the Enhancement of Voltage Profile and Loss Minimization in Transmission Systems Using Nature Inspired Algorithms.

    PubMed

    Ramamoorthy, Ambika; Ramachandran, Rajeswari

    2016-01-01

    Power grid becomes smarter nowadays along with technological development. The benefits of smart grid can be enhanced through the integration of renewable energy sources. In this paper, several studies have been made to reconfigure a conventional network into a smart grid. Amongst all the renewable sources, solar power takes the prominent position due to its availability in abundance. Proposed methodology presented in this paper is aimed at minimizing network power losses and at improving the voltage stability within the frame work of system operation and security constraints in a transmission system. Locations and capacities of DGs have a significant impact on the system losses in a transmission system. In this paper, combined nature inspired algorithms are presented for optimal location and sizing of DGs. This paper proposes a two-step optimization technique in order to integrate DG. In a first step, the best size of DG is determined through PSO metaheuristics and the results obtained through PSO is tested for reverse power flow by negative load approach to find possible bus locations. Then, optimal location is found by Loss Sensitivity Factor (LSF) and weak (WK) bus methods and the results are compared. In a second step, optimal sizing of DGs is determined by PSO, GSA, and hybrid PSOGSA algorithms. Apart from optimal sizing and siting of DGs, different scenarios with number of DGs (3, 4, and 5) and PQ capacities of DGs (P alone, Q alone, and P and Q both) are also analyzed and the results are analyzed in this paper. A detailed performance analysis is carried out on IEEE 30-bus system to demonstrate the effectiveness of the proposed methodology.

  13. Optimal Siting and Sizing of Multiple DG Units for the Enhancement of Voltage Profile and Loss Minimization in Transmission Systems Using Nature Inspired Algorithms

    PubMed Central

    Ramamoorthy, Ambika; Ramachandran, Rajeswari

    2016-01-01

    Power grid becomes smarter nowadays along with technological development. The benefits of smart grid can be enhanced through the integration of renewable energy sources. In this paper, several studies have been made to reconfigure a conventional network into a smart grid. Amongst all the renewable sources, solar power takes the prominent position due to its availability in abundance. Proposed methodology presented in this paper is aimed at minimizing network power losses and at improving the voltage stability within the frame work of system operation and security constraints in a transmission system. Locations and capacities of DGs have a significant impact on the system losses in a transmission system. In this paper, combined nature inspired algorithms are presented for optimal location and sizing of DGs. This paper proposes a two-step optimization technique in order to integrate DG. In a first step, the best size of DG is determined through PSO metaheuristics and the results obtained through PSO is tested for reverse power flow by negative load approach to find possible bus locations. Then, optimal location is found by Loss Sensitivity Factor (LSF) and weak (WK) bus methods and the results are compared. In a second step, optimal sizing of DGs is determined by PSO, GSA, and hybrid PSOGSA algorithms. Apart from optimal sizing and siting of DGs, different scenarios with number of DGs (3, 4, and 5) and PQ capacities of DGs (P alone, Q alone, and  P and Q both) are also analyzed and the results are analyzed in this paper. A detailed performance analysis is carried out on IEEE 30-bus system to demonstrate the effectiveness of the proposed methodology. PMID:27057557

  14. Gran Telescopio Canarias Commissioning Instrument Optomechanics

    NASA Astrophysics Data System (ADS)

    Espejo, Carlos; Cuevas, Salvador; Sanchez, Beatriz; Flores, Ruben; Lara, Gerardo; Farah, Alejandro; Godoy, Javier; Bringas, Vicente; Chavoya, Armando; Dorantes, Ariel; Manuel Montoya, Juan; Rangel, Juan Carlos; Devaney, Nicholas; Castro, Javier; Cavaller, Luis

    2003-02-01

    Under a contract with the GRANTECAN, the Commissioning Instrument is a project developed by a team of Mexican scientists and engineers from the Instrumentation Department of the Astronomy Institute at the UNAM and the CIDESI Engineering Center. This paper will discuss in some detail the final Commissioning Instrument (CI) mechanical design and fabrication. We will also explain the error budget and the barrels design as well as their thermal compensation. The optical design and the control system are discussed in other papers. The CI will just act as a diagnostic tool for image quality verification during the GTC Commissioning Phase. This phase is a quality control process for achieving, verifying, and documenting the performance of each GTC sub-systems. This is a very important step for the telescope life. It will begin on starting day and will last for a year. The CI project started in December 2000. The critical design phase was reviewed in July 2001. The CI manufacturing is currently in progress and most parts are finished. We are now approaching the factory acceptance stage.

  15. Commissioning Experience for the SNS Linac

    SciTech Connect

    Aleksandrov, A.; Assadi, S.; Campisi, I.; Chu, P.; Cousineau, S.; Danilov, V.; Dodson, B.G.; Galambos, J.; Jeon, D.; Henderson, S.; Holtkamp, N.; Kravchuk, L.; Kim, S.; Plum, M.; Tanke, E.; Stockli, M.

    2005-06-08

    The Spallation Neutron Source accelerator systems will deliver a 1 GeV, 1.44 MW proton beam to a liquid mercury target for neutron scattering research. The accelerator complex consists of an H- injector, capable of producing one-ms-long pulses at 60 Hz repetition rate with 38 mA peak current, a 1 GeV linear accelerator, an accumulator ring and associated transport lines. A 2.5 MeV beam from the Front End is accelerated to 86 MeV in a Drift Tube Linac, then to 185 MeV in a Coupled-Cavity Linac and then to 1 GeV in a Superconducting Linac. The staged beam commissioning of the accelerator complex is proceeding as component installation progresses. The Front End, Drift Tube Linac and part of the Coupled-Cavity Linac have been commissioned at ORNL. The primary design goals of peak current, transverse emittance and beam energy have been achieved. Results and status of the beam commissioning program will be presented.

  16. Commissioning an Engineering Scale Coal Gasifier

    SciTech Connect

    Reid, Douglas J.; Bearden, Mark D.; Cabe, James E.

    2010-07-01

    This report explains the development, commissioning, and testing of an engineering scale slagging coal gasifier at PNNL. The initial objective of this project was to commission the gasifier with zero safety incidents. The commissioning work was primarily an empirical study that required an engineering design approach. After bringing the gasifier on-line, tests were conducted to assess the impact of various operating parameters on the synthesis gas (syngas) product composition. The long-term intent of this project is to produce syngas product for use by internal Pacific Northwest National Laboratory (PNNL) researchers in catalyst, materials, and instrumentation development. Future work on the project will focus on improving the reliability and performance of the gasifier, with a goal of continuous operation for greater than 4 hours using coal feedstock. In addition, alternate designs that allow for increased flexibility regarding the fuel sources that can be used for syngas production is desired. Continued modifications to the fuel feed system will be pursued to address these goals. Alternative feed mechanisms such as a coal/methanol slurry are being considered.

  17. Commissioning of the CMS Forward Pixel Detector

    SciTech Connect

    Kumar, Ashish; /SUNY, Buffalo

    2008-12-01

    The Compact Muon Solenoid (CMS) experiment is scheduled for physics data taking in summer 2009 after the commissioning of high energy proton-proton collisions at Large Hadron Collider (LHC). At the core of the CMS all-silicon tracker is the silicon pixel detector, comprising three barrel layers and two pixel disks in the forward and backward regions, accounting for a total of 66 million channels. The pixel detector will provide high-resolution, 3D tracking points, essential for pattern recognition and precise vertexing, while being embedded in a hostile radiation environment. The end disks of the pixel detector, known as the Forward Pixel detector, has been assembled and tested at Fermilab, USA. It has 18 million pixel cells with dimension 100 x 150 {micro}m{sup 2}. The complete forward pixel detector was shipped to CERN in December 2007, where it underwent extensive system tests for commissioning prior to the installation. The pixel system was put in its final place inside the CMS following the installation and bake out of the LHC beam pipe in July 2008. It has been integrated with other sub-detectors in the readout since September 2008 and participated in the cosmic data taking. This report covers the strategy and results from commissioning of CMS forward pixel detector at CERN.

  18. Practical Diagnostics for Evaluating Residential Commissioning Metrics

    SciTech Connect

    Wray, Craig; Walker, Iain; Siegel, Jeff; Sherman, Max

    2002-06-11

    In this report, we identify and describe 24 practical diagnostics that are ready now to evaluate residential commissioning metrics, and that we expect to include in the commissioning guide. Our discussion in the main body of this report is limited to existing diagnostics in areas of particular concern with significant interactions: envelope and HVAC systems. These areas include insulation quality, windows, airtightness, envelope moisture, fan and duct system airflows, duct leakage, cooling equipment charge, and combustion appliance backdrafting with spillage. Appendix C describes the 83 other diagnostics that we have examined in the course of this project, but that are not ready or are inappropriate for residential commissioning. Combined with Appendix B, Table 1 in the main body of the report summarizes the advantages and disadvantages of all 107 diagnostics. We first describe what residential commissioning is, its characteristic elements, and how one might structure its process. Our intent in this discussion is to formulate and clarify these issues, but is largely preliminary because such a practice does not yet exist. Subsequent sections of the report describe metrics one can use in residential commissioning, along with the consolidated set of 24 practical diagnostics that the building industry can use now to evaluate them. Where possible, we also discuss the accuracy and usability of diagnostics, based on recent laboratory work and field studies by LBNL staff and others in more than 100 houses. These studies concentrate on evaluating diagnostics in the following four areas: the DeltaQ duct leakage test, air-handler airflow tests, supply and return grille airflow tests, and refrigerant charge tests. Appendix A describes those efforts in detail. In addition, where possible, we identify the costs to purchase diagnostic equipment and the amount of time required to conduct the diagnostics. Table 1 summarizes these data. Individual equipment costs for the 24

  19. European Composite Honeycomb Material

    NASA Astrophysics Data System (ADS)

    Tschepe, Christoph; Sauerbrey, Martin; Klebor, Maximillian; Henriksen, Torben

    2014-06-01

    A European CFRP honeycomb material for high demanding structure applications like antenna reflectors and optical benches was developed in the frame of an ESA GSTP project.The composite honeycomb was designed according to requirements defined by the European space industry. A developed manufacturing technique based on prepreg moulding enables the production of homogeneous CFRP honeycomb blocks. All characteristic material properties, including compression, tension and shear strength and CTE, were determined in a comprehensive verification test campaign. Competitiveness to comparable products was further verified by a representative breadboard.

  20. European security and France

    SciTech Connect

    deRose, A.

    1985-01-01

    A French authority on security argues for new European initiatives in the face of the ''danger represented by Soviet military power deployed in support of an imperialistic ideology.'' His proposals, including the strengthening of conventional forces without abandoning the option of the first use of nuclear weapons, are meant to give substance to President Mitterrand's declaration in 1983: ''The European nations now need to realize that their defense is also their responsibility....'' A part of the increasingly important debate in France over defense policy in Europe.

  1. EDITORIAL: The 15th Central European Workshop on Quantum Optics The 15th Central European Workshop on Quantum Optics

    NASA Astrophysics Data System (ADS)

    Bozic, Mirjana; Man'ko, Margarita; Arsenovic, Dusan

    2009-07-01

    The development of quantum optics was part and parcel of the formation of modern physics following the fundamental work of Max Planck and Albert Einstein, which gave rise to quantum mechanics. The possibility of working with pure quantum objects, like single atoms and single photons, has turned quantum optics into the main tool for testing the fundamentals of quantum physics. Thus, despite a long history, quantum optics nowadays remains an extremely important branch of physics. It represents a natural base for the development of advanced technologies, like quantum information processing and quantum computing. Previous Central European Workshops on Quantum Optics (CEWQO) took place in Palermo (2007), Vienna (2006), Ankara (2005), Trieste (2004), Rostock (2003), Szeged (2002), Prague (2001), Balatonfüred (2000), Olomouc (1999), Prague (1997), Budmerice (1995, 1996), Budapest (1994) and Bratislava (1993). Those meetings offered excellent opportunities for the exchange of knowledge and ideas between leading scientists and young researchers in quantum optics, foundations of quantum mechanics, cavity quantum electrodynamics, photonics, atom optics, condensed matter optics, and quantum informatics, etc. The collaborative spirit and tradition of CEWQO were a great inspiration and help to the Institute of Physics, Belgrade, and the Serbian Academy of Sciences and Arts, as the organizers of CEWQO 2008. The 16th CEWQO will take place in 2009 in Turku, Finland, and the 17th CEWQO will be organized in 2010 in St Andrews, United Kingdom. The 15th CEWQO was organized under the auspices and support of the Ministry of Science of the Republic of Serbia, the Serbian Physical Society, the European Physical Society with sponsorship from the University of Belgrade, the Central European Initiative, the FP6 Program of the European Commission under INCO project QUPOM No 026322, the FP7 Program of the European Commission under project NANOCHARM, Europhysics Letters (EPL), The European

  2. Investigation of the persistence of new building commissioning

    SciTech Connect

    Potter, Amanda; Friedman, Hannah; Haasl, Tudi; Claridge, David

    2002-03-17

    Commissioning is gaining increasing recognition as a cost-effective strategy for reducing commercial building energy use. Although the success and cost-effectiveness of commissioning projects depends on how well the benefits of commissioning persist over time, this aspect of commissioning is not well understood. The persistence of commissioning benefits was recently studied in a PIER project evaluating ten buildings that were commissioned at building start-up at least two years ago. The researchers examined the commissioning reports, control algorithms, EMCS point measurements, and energy use data, and conducted operator and commissioning provider interviews to investigate the persistence of commissioning benefits. In addition, they conducted site visits in a sample of the buildings. A set of commissioning measures was selected for each building to compare the persistence of benefits. Persistence was measured both qualitatively through a discussion of occupant comfort and decreased maintenance and quantitatively through estimations of energy savings. This paper reports the results of the study. The discussion includes how well the benefits of commissioning persisted over time, reasons for declining performance, and methods for improving persistence. The results provide valuable insight into how to estimate the persistence of commissioning information central to the cost benefit analyses routinely performed for commissioning measures.

  3. Dynamic Control System Performance during Commissioning of the Space Technology 7-Disturbance Reduction System Experiment of LISA Pathfinder

    NASA Technical Reports Server (NTRS)

    Hsu, Oscar; Maghami, Peiman; O’Donnell, James R., Jr.; Ziemer, John; Romero-Wolf, Andrew

    2017-01-01

    The Space Technology-7 Disturbance Reduction System (DRS) launched aboard the European Space Agency's LISA Pathfinder spacecraft on December 3, 2015, after more than a decade in development. DRS consists of three primary components: an Integrated Avionics Unit (IAU), Colloidal MicroNewton Thrusters, and Dynamic Control System (DCS) algorithms implemented on the IAU. During the portions of the mission in which the DRS was under control, the DCS was responsible for controlling the spacecraft and the free-floating test masses that were part of the LISA Test Package. The commissioning period was originally divided into two periods: before propulsion separation and after propulsion separation. A recommissioning period was added after an anomaly occurred in the thruster system. The paper will describe the activities used to commission DRS, present results from the commissioning of the DCS and the recommissioning activities per-formed after the thruster anomaly.

  4. New European Training Network to Improve Young Scientists' Capabilities in Computational Wave Propagation

    NASA Astrophysics Data System (ADS)

    Igel, Heiner

    2004-07-01

    The European Commission recently funded a Marie-Curie Research Training Network (MCRTN) in the field of computational seismology within the 6th Framework Program. SPICE (Seismic wave Propagation and Imaging in Complex media: a European network) is coordinated by the computational seismology group of the Ludwig-Maximilians-Universität in Munich linking 14 European research institutions in total. The 4-year project will provide funding for 14 Ph.D. students (3-year projects) and 14 postdoctoral positions (2-year projects) within the various fields of computational seismology. These positions have been advertised and are currently being filled.

  5. Human vaccine research in the European Union.

    PubMed

    Olesen, Ole F; Lonnroth, Anna; Mulligan, Bernard

    2009-01-29

    The use of vaccines is saving millions of lives every year across the globe, but a number of important diseases such as HIV/AIDS, malaria, TB and hepatitis C continue to frustrate attempts to produce effective vaccines against them. Confronting these challenges will require new approaches and increased research efforts by the scientific community. The Sixth Framework Programme (FP6; 2002-2006) of the European Commission (EC) has been an important catalyst in this direction by allocating a financial contribution of more than EUR 210 million to a wide variety of vaccine research activities, ranging from basic vaccinology, translational research to clinical application of vaccines. Taken together, around 581 research groups from 52 countries are participating in the vaccine activities of FP6. This impressive number signals a new spirit of collaborative research, which will facilitate the exploitation of the immense possibilities in modern vaccinology.

  6. European tendencies and co-operation in the field of ITS systems - national achievements and challenges in Hungary

    NASA Astrophysics Data System (ADS)

    Lindenbach, Ágnes

    2016-06-01

    The article presents the role of intelligent transport systems/services related to the implementation of the essential European and Hungarian transport policy objectives. The `ITS Directive' will provide a framework for the tasks/works to be performed in the forthcoming years within the priority areas of ITS. The European Commission published regulations / specifications for the priority actions in the form of delegated acts defining the tasks/responsibilities of Member States. Regional/European co-operation for Hungary started after the EU-accession of the country. Hungary was an active partner within the European CONNECT and EasyWay projects, currently Hungary is a member of the CROCODILE consortium.

  7. European Marine Infrastructures: perspectives for Marine and Earth Sciences

    NASA Astrophysics Data System (ADS)

    Favali, P.; Beranzoli, L.; Egerton, P.; Le Traon, P. Y.; Los, W.

    2009-04-01

    The European Commission (EC) is supporting a variety of Research Infrastructures in many different scientific fields: Social Sciences and Humanities, Environmental Sciences, Energy, Biological and Medical Sciences, Physical Sciences and Engineering and e-Infrastructures. All these infrastructures are included in the new report of the "European Roadmap for Research Infrastructures" published in late 2008 by ESFRI (European Strategy Forum on Research Infrastructures, http://cordis.europa.eu/esfri/). In particular, some research infrastructures for the Environmental Sciences specifically addressed to the marine environment are presented: • EMSO (European Multidisciplinary Seafloor Observatory). The development of this underwater network is being supported by several other EC initiatives, ESONET-NoE (European Seas Network), coordinated by IFREMER (http://www.esonet-emso.org/esonet-noe/). • ERICON AURORA BOREALIS (European Research Icebreaker Consortium, http://www.eri-aurora-borealis.eu/). • EURO-ARGO (Global Ocean Observing Infrastructure, http://www.euro-argo.eu/). • LIFEWATCH (E-science and technology infrastructure for biodiversity data and observatories, http://www.lifewatch.eu/). In particular through its scientific marine networks: EUR-OCEANS (European Network of Excellence for Ocean Ecosystems Analysis, http://www.eur-oceans.eu/); MARBEF-NoE (MARine Biodiversity and Ecosystem Functioning, http://www.marbef.org/ and Marine Genomics (http://www.marine-genomics-europe.org/). Possible profitable links with new research infrastructures recently included in the roadmap, such as EPOS (European Plate Observing System) and SIAEOS (Svalbard Integrated Arctic Earth Observing System) are also pointed out. The marine EC infrastructures presented constitute the fundamental tools to support the Earth Sciences, both terrestrial and marine.

  8. European Civilization. Teacher's Manual.

    ERIC Educational Resources Information Center

    Leppert, Ella C.; Halac, Dennis

    The instructional materials in this teaching guide for Course II, Unit IV, follow and build upon a previous sequential course described in SO 003 169 offering ninth grade students a study on the development of Western European Civilization. Focus is upon four periods of high development: The High Middle Ages (12th Century), The Renaissance (15th…

  9. The European VLBI network

    NASA Technical Reports Server (NTRS)

    Schilizzi, R. T.

    1980-01-01

    The capabilities of the European very long baseline interferometry (VLBI) network are summarized. The range of baseline parameters, sensitivities, and recording and other equipment available are included. Plans for upgrading the recording facilities and the use of geostationary satellites for signal transfer and clock synchronization are discussed.

  10. European Study Tour Guidelines.

    ERIC Educational Resources Information Center

    Mitchell, Vicki L.; Mitchell, Kenneth E.

    Guidelines are presented for planning and financing European study tours at the community college level. First, a rationale for incorporating study tours of Europe within the community college curriculum is presented and the benefits of such tours in providing students with experiences they could not normally have are outlined. Next, the paper…

  11. European Music Year 1985.

    ERIC Educational Resources Information Center

    Alexanderson, Thomas; And Others

    1984-01-01

    Articles concerning music are included in this newsletter dedicated to cultural venture to be jointly carried out by the Council of Europe and the European communities. Many events will mark Music Year 1985, including concerts, dance performances, operas, publications, recordings, festivals, exhibitions, competitions, and conferences on musical…

  12. Multilingualism in European Workplaces

    ERIC Educational Resources Information Center

    Gunnarsson, Britt-Louise

    2014-01-01

    This state-of-the-art article includes a review of past and recent studies on multilingualism at work in European environments. One aim is to provide the reader with a cross-cultural picture of workplace studies on various languages in Europe, another to discuss both positive and problem-based accounts of multilingualism at work. The overview…

  13. Teaching European Identities

    ERIC Educational Resources Information Center

    Raento, Pauliina

    2008-01-01

    The political, cultural and social make-up of Europe is changing fast. A new European identity is under construction, but old contradictions and diversity challenge its contents, forms and boundaries. Migration, the changing role of the nation-state and Europe's regions, the reshaping of politico-administrative and perceptional boundaries, the…

  14. The Road to the European Union: Macroeconomic Policy Challenges for Hungary and Poland. Fulbright-Hayes Summer Seminars Abroad Program, 2002 (Hungary and Poland).

    ERIC Educational Resources Information Center

    Ramirez, Teresita R.

    Prospects for the enlargement of the European Union (EU) became imminent when the EU Commission agreed in 1997 to open formal negotiations with five of the Central and Eastern European countries: (1) the Czech Republic; (2) Hungary; (3) Poland; (4) Slovenia; and (5) Estonia. This research project discusses macroeconomic policy challenges that…

  15. A Perception Survey for the Evaluation of Urban Quality of Life in Kocaeli and a Comparison of the Life Satisfaction with the European Cities

    ERIC Educational Resources Information Center

    Senlier, Nihal; Yildiz, Reyhan; Aktas, E. Digdem

    2009-01-01

    Studies on urban quality of life (QoL) have been attracting lots of attention from various countries due to the deterioration of urban environment and decrease of the urban QoL. These studies that have been supported by international organizations such as United Nations, World Bank, OECD, European Commission and EUROSTAT (European Statistics)…

  16. 29 CFR 2203.3 - Public attendance at Commission meetings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or for the use of an agency responsible for the regulation or supervision of financial institutions... Commission's issuance of a subpoena or the Commission's participation in a civil action or proceeding,...

  17. 29 CFR 2203.3 - Public attendance at Commission meetings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., or for the use of an agency responsible for the regulation or supervision of financial institutions... Commission's issuance of a subpoena or the Commission's participation in a civil action or proceeding,...

  18. 29 CFR 2203.3 - Public attendance at Commission meetings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., or for the use of an agency responsible for the regulation or supervision of financial institutions... Commission's issuance of a subpoena or the Commission's participation in a civil action or proceeding,...

  19. Report of the State of Nevada Commission on Nuclear Projects

    SciTech Connect

    1990-12-01

    This third biennial Report of the Nevada Commission on Nuclear Projects has been prepared in fulfillment of the requirements of NRS 459.0092, which stipulates that the Commission shall report to the Governor and Legislature on any matter relating to radioactive waste disposal the Commission deems appropriate and advise and make recommendations on the policy of the State concerning nuclear waste disposal projects. Chapter One of the Report presents a brief overview of the Commission`s functions and statutory charges. It also contains a summary of developments which have affected the overall nuclear waste disposl issue since the last Commission Report was published in November, 1988. Chapter Two contains a synthesis of Commission activities and reports on the findings of the Commission relative to the geotechnical, environmental, socioeconomic, transportation, intergovernmental and legal aspects of federal and State nuclear waste program efforts.

  20. 32 CFR 9.2 - Establishment of Military Commissions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM § 9.2 Establishment of Military Commissions. In accordance with the President's Military...