Multi-Year Elevation Changes Near the West Margin of the Greenland Ice Sheet from Satellite Radar Altimetry

NASA Technical Reports Server (NTRS)

Lingle, Craig S.; Brenner, Anita C.; Zwally, H. Jay; DiMarzio, John P.

1991-01-01

Mean changes in the surface elevation near the west margin of the Greenland ice sheet are measured using Seasat altimetry and altimetry from the Geosat Exact Repeat Mission (ERM). The Seasat data extend from early July through early October 1978. The ERM data extend from winter 1986-87 through fall 1988. Both seasonal and multi-year changes are measured using altimetry referenced to GEM T2 orbits. The possible effects of orbit error are minimized by adjusting the orbits into a common ocean surface. Seasonal mean changes in the surface height are recognizable during the Geosat ERM. The multi-year measurements indicate the surface was lower by 0.4 +/- 0.4 m on average in late summer 1987 than in late summer 1978. The surface was lower by 0.2 +/- 0.5 m on average in late summer 1988 than in late summer 1978. As a control case, the computations art also carried out using altimetry referenced to orbits not adjusted into a common ocean surface.

Transport of the Norwegian Atlantic current as determined from satellite altimetry

NASA Technical Reports Server (NTRS)

Pistek, Pavel; Johnson, Donald R.

1992-01-01

Relatively warm and salty North Atlantic surface waters flow through the Faeroe-Shetland Channel into the higher latitudes of the Nordic Seas, preserving an ice-free winter environment for much of the exterior coast of northern Europe. This flow was monitored along the Norwegian coast using Geosat altimetry on two ascending arcs during the Exact Repeat Mission in 1987-1989. Concurrent undertrack CTD surveys were used to fix a reference surface for the altimeter-derived SSH anomalies, in effect creating time series of alongtrack surface dynamic height topographies. Climatologic CTD casts were then used, with empirical orthogonal function (EOF) analysis, to derive relationships between historical surface dynamic heights and vertical temperature and salinity profiles. Applying these EOF relationships to the altimeter signals, mean transports of volume, heat, and salt were calculated at approximately 2.9 Sverdrups, 8.1 x 10 exp 11 KCal/s and 1.0 x 10 exp 8 Kg/s, respectively. Maximum transports occurred in February/March and minimum in July/August.

Rapidly deployable emergency communication system

DOEpatents

Gladden, Charles A.; Parelman, Martin H.

1979-01-01

A highly versatile, highly portable emergency communication system which permits deployment in a very short time to cover both wide areas and distant isolated areas depending upon mission requirements. The system employs a plurality of lightweight, fully self-contained repeaters which are deployed within the mission area to provide communication between field teams, and between each field team and a mobile communication control center. Each repeater contains a microcomputer controller, the program for which may be changed from the control center by the transmission of digital data within the audible range (300-3,000 Hz). Repeaters are accessed by portable/mobile transceivers, other repeaters, and the control center through the transmission and recognition of digital data code words in the subaudible range.

Future space transportation systems analysis study. Phase 1 extension: Transportation systems reference data, volume 2

NASA Technical Reports Server (NTRS)

1975-01-01

Transportation mass requirements are developed for various mission and transportation modes based on vehicle systems sized to fit the exact needs of each mission. The parametric data used to derive the mass requirements for each mission and transportation mode are presented to enable accommodation of possible changes in mode options or payload definitions. The vehicle sizing and functional requirements used to derive the parametric data are described.

Rate-loss analysis of an efficient quantum repeater architecture

NASA Astrophysics Data System (ADS)

Guha, Saikat; Krovi, Hari; Fuchs, Christopher A.; Dutton, Zachary; Slater, Joshua A.; Simon, Christoph; Tittel, Wolfgang

2015-08-01

We analyze an entanglement-based quantum key distribution (QKD) architecture that uses a linear chain of quantum repeaters employing photon-pair sources, spectral-multiplexing, linear-optic Bell-state measurements, multimode quantum memories, and classical-only error correction. Assuming perfect sources, we find an exact expression for the secret-key rate, and an analytical description of how errors propagate through the repeater chain, as a function of various loss-and-noise parameters of the devices. We show via an explicit analytical calculation, which separately addresses the effects of the principle nonidealities, that this scheme achieves a secret-key rate that surpasses the Takeoka-Guha-Wilde bound—a recently found fundamental limit to the rate-vs-loss scaling achievable by any QKD protocol over a direct optical link—thereby providing one of the first rigorous proofs of the efficacy of a repeater protocol. We explicitly calculate the end-to-end shared noisy quantum state generated by the repeater chain, which could be useful for analyzing the performance of other non-QKD quantum protocols that require establishing long-distance entanglement. We evaluate that shared state's fidelity and the achievable entanglement-distillation rate, as a function of the number of repeater nodes, total range, and various loss-and-noise parameters of the system. We extend our theoretical analysis to encompass sources with nonzero two-pair-emission probability, using an efficient exact numerical evaluation of the quantum state propagation and measurements. We expect our results to spur formal rate-loss analysis of other repeater protocols and also to provide useful abstractions to seed analyses of quantum networks of complex topologies.

Simulation and analysis of a geopotential research mission

NASA Technical Reports Server (NTRS)

White, Lisa K.

1987-01-01

Methods for the determination of the initial conditions for the two satellites that will satisfy Geopotential Research Mission (GRM) requirements are investigated. For certain gravitational recovery techniques, the satellites must remain close to a specified separation distance and their groundtracks must repeat after a specified interval of time. Since the objective of the GRM mission is to improve the gravity model, any pre-mission orbit predicted using existing gravity models will be in error. A technique has been developed to eliminate the drift between the two satellites caused by gravitational modeling errors and return them to repeating groundtracks. The concept of frozen orbits, which minimize altitude variations over given latitudes, was investigated. Finally, the effects of temporal perturbations on the relative range-rate signal were studied. At the proposed altitude of 160 km, the range-rate signal produced by perturbations other than the static geopotential field are dominated by the luni-solar effect. This study demonstrates that the combined effects of all the temporal perturbations does not prevent the orbit from being frozen or the satellites from obtaining a repeating groundtrack to within a specified closure distance.

Orbit Selection for Earth Observation Missions

NASA Technical Reports Server (NTRS)

King, J. C.

1978-01-01

The orbit selection process is simplified for most earth-oriented satellite missions by a restriction to circular orbits, which reduces the primary orbit characteristics to be determined to only two: altitude and inclination. A number of important mission performance characteristics depend on these choices, however, so a major part of the orbit selection task is concerned with developing the correlating relationships in clear and convenient forms to provide a basis for rational orbit selection procedures. The present approach to that task is organized around two major areas of mission performance, orbit plane precession and coverage pattern development, whose dependence on altitude and inclination is delineated graphically in design chart form. These charts provide a visual grasp of the relationships between the quantities cited above, as well as other important mission performance parameters including viewing time of day (solar), sensor swath width (and fields of view), swath sequencing, and pattern repeat condition and repeat periods.

Aesthetic Responses to Exact Fractals Driven by Physical Complexity

PubMed Central

Bies, Alexander J.; Blanc-Goldhammer, Daryn R.; Boydston, Cooper R.; Taylor, Richard P.; Sereno, Margaret E.

2016-01-01

Fractals are physically complex due to their repetition of patterns at multiple size scales. Whereas the statistical characteristics of the patterns repeat for fractals found in natural objects, computers can generate patterns that repeat exactly. Are these exact fractals processed differently, visually and aesthetically, than their statistical counterparts? We investigated the human aesthetic response to the complexity of exact fractals by manipulating fractal dimensionality, symmetry, recursion, and the number of segments in the generator. Across two studies, a variety of fractal patterns were visually presented to human participants to determine the typical response to exact fractals. In the first study, we found that preference ratings for exact midpoint displacement fractals can be described by a linear trend with preference increasing as fractal dimension increases. For the majority of individuals, preference increased with dimension. We replicated these results for other exact fractal patterns in a second study. In the second study, we also tested the effects of symmetry and recursion by presenting asymmetric dragon fractals, symmetric dragon fractals, and Sierpinski carpets and Koch snowflakes, which have radial and mirror symmetry. We found a strong interaction among recursion, symmetry and fractal dimension. Specifically, at low levels of recursion, the presence of symmetry was enough to drive high preference ratings for patterns with moderate to high levels of fractal dimension. Most individuals required a much higher level of recursion to recover this level of preference in a pattern that lacked mirror or radial symmetry, while others were less discriminating. This suggests that exact fractals are processed differently than their statistical counterparts. We propose a set of four factors that influence complexity and preference judgments in fractals that may extend to other patterns: fractal dimension, recursion, symmetry and the number of segments in a pattern. Conceptualizations such as Berlyne’s and Redies’ theories of aesthetics also provide a suitable framework for interpretation of our data with respect to the individual differences that we detect. Future studies that incorporate physiological methods to measure the human aesthetic response to exact fractal patterns would further elucidate our responses to such timeless patterns. PMID:27242475

[The mission].

PubMed

Ruiz Moreno, J; Blanch Mon, A

2000-01-01

After having made a historical review of the concept of mission statement, of evaluating its importance (See Part I), of describing the bases to create a mission statement from a strategic perspective and of analyzing the advantages of this concept, probably more important as a business policy (See Parts I and II), the authors proceed to analyze the mission statement in health organizations. Due to the fact that a mission statement is lacking in the majority of health organizations, the strategy of health organizations are not exactly favored; as a consequence, neither are its competitive advantage nor the development of its essential competencies. After presenting a series of mission statements corresponding to Anglo-Saxon health organizations, the authors highlight two mission statements corresponding to our social context. The article finishes by suggesting an adequate sequence for developing a mission statement in those health organizations having a strategic sense.

Let's Get This Party Started: Pump up the Volume. Streaming Music Is a Great Way to Connect with Older Kids

ERIC Educational Resources Information Center

Pritchard, Kate

2010-01-01

It's not always easy to get teens talking. But when the author became a young adult specialist at the Wilbraham (Massachusetts) Public Library four years ago, that's exactly what she had to do. Her main mission was to bring in as many high schoolers as possible. She needed to find out exactly what they wanted from the library. when she asked them…

The human genome as "common good".

PubMed

Vesto, Aurora

2017-07-01

Objectivity of rights must be rebuilt in a dimension not only structural but also functional, despite being a "thing" that exactly repeats itself, it differs depending on what the person intended to make.

Distribution of Reynolds stress carried by mesoscale variability in the Antarctic Circumpolar Current

NASA Technical Reports Server (NTRS)

Johnson, Thomas J.; Stewart, Robert H.; Shum, C. K.; Tapley, Byron D.

1992-01-01

Satellite altimeter data collected by the Geosat Exact Repeat Mission were used to investigate turbulent stress resulting from the variability of surface geostrophic currents in the Antarctic Circumpolar Current. The altimeter measured sea level along the subsatellite track. The variability of the along-track slope of sea level is directly proportional to the variability of surface geostrophic currents in the cross-track direction. Because the grid of crossover points is dense at high latitudes, the satellite data could be used for mapping the temporal and spatial variability of the current. Two and a half years of data were used to compute the statistical structure of the variability. The statistics included the probability distribution functions for each component of the current, the time-lagged autocorrelation functions of the variability, and the Reynolds stress produced by the variability. The results demonstrate that stress is correlated with bathymetry. In some areas the distribution of negative stress indicate that eddies contribute to an acceleration of the mean flow, strengthening the hypothesis that baroclinic instability makes important contributions to strong oceanic currents.

Modelling of Picosatellite Constellation-Based Network and Effects on Quality of Service

DTIC Science & Technology

2015-03-01

the STK -QualNet Interface module. The analysis period for the scenario simulation was chosen as a two-day period from 6 June 2011 to 7 June 2011. This...MIN 0:00:04 0:00:34 AVERAGE 0:58:03 0:21:21 27 THIS PAGE INTENTIONALLY LEFT BLANK 28 VI. DATA ANALYSIS /INTERPRETATION The STK model was... Mission Analysis and Design, 3rd ed. (Space Technology Library, vol. 8). El Segundo, CA: Microcosm, 1999. [5] exactEarth. (2015). ExactView

The mean and variance of phylogenetic diversity under rarefaction

PubMed Central

Matsen, Frederick A.

2013-01-01

Summary Phylogenetic diversity (PD) depends on sampling depth, which complicates the comparison of PD between samples of different depth. One approach to dealing with differing sample depth for a given diversity statistic is to rarefy, which means to take a random subset of a given size of the original sample. Exact analytical formulae for the mean and variance of species richness under rarefaction have existed for some time but no such solution exists for PD.We have derived exact formulae for the mean and variance of PD under rarefaction. We confirm that these formulae are correct by comparing exact solution mean and variance to that calculated by repeated random (Monte Carlo) subsampling of a dataset of stem counts of woody shrubs of Toohey Forest, Queensland, Australia. We also demonstrate the application of the method using two examples: identifying hotspots of mammalian diversity in Australasian ecoregions, and characterising the human vaginal microbiome.There is a very high degree of correspondence between the analytical and random subsampling methods for calculating mean and variance of PD under rarefaction, although the Monte Carlo method requires a large number of random draws to converge on the exact solution for the variance.Rarefaction of mammalian PD of ecoregions in Australasia to a common standard of 25 species reveals very different rank orderings of ecoregions, indicating quite different hotspots of diversity than those obtained for unrarefied PD. The application of these methods to the vaginal microbiome shows that a classical score used to quantify bacterial vaginosis is correlated with the shape of the rarefaction curve.The analytical formulae for the mean and variance of PD under rarefaction are both exact and more efficient than repeated subsampling. Rarefaction of PD allows for many applications where comparisons of samples of different depth is required. PMID:23833701

The mean and variance of phylogenetic diversity under rarefaction.

PubMed

Nipperess, David A; Matsen, Frederick A

2013-06-01

Phylogenetic diversity (PD) depends on sampling depth, which complicates the comparison of PD between samples of different depth. One approach to dealing with differing sample depth for a given diversity statistic is to rarefy, which means to take a random subset of a given size of the original sample. Exact analytical formulae for the mean and variance of species richness under rarefaction have existed for some time but no such solution exists for PD.We have derived exact formulae for the mean and variance of PD under rarefaction. We confirm that these formulae are correct by comparing exact solution mean and variance to that calculated by repeated random (Monte Carlo) subsampling of a dataset of stem counts of woody shrubs of Toohey Forest, Queensland, Australia. We also demonstrate the application of the method using two examples: identifying hotspots of mammalian diversity in Australasian ecoregions, and characterising the human vaginal microbiome.There is a very high degree of correspondence between the analytical and random subsampling methods for calculating mean and variance of PD under rarefaction, although the Monte Carlo method requires a large number of random draws to converge on the exact solution for the variance.Rarefaction of mammalian PD of ecoregions in Australasia to a common standard of 25 species reveals very different rank orderings of ecoregions, indicating quite different hotspots of diversity than those obtained for unrarefied PD. The application of these methods to the vaginal microbiome shows that a classical score used to quantify bacterial vaginosis is correlated with the shape of the rarefaction curve.The analytical formulae for the mean and variance of PD under rarefaction are both exact and more efficient than repeated subsampling. Rarefaction of PD allows for many applications where comparisons of samples of different depth is required.

Study of spin-scan imaging for outer planets missions. [imaging techniques for Jupiter orbiter missions

NASA Technical Reports Server (NTRS)

Russell, E. E.; Chandos, R. A.; Kodak, J. C.; Pellicori, S. F.; Tomasko, M. G.

1974-01-01

The constraints that are imposed on the Outer Planet Missions (OPM) imager design are of critical importance. Imager system modeling analyses define important parameters and systematic means for trade-offs applied to specific Jupiter orbiter missions. Possible image sequence plans for Jupiter missions are discussed in detail. Considered is a series of orbits that allow repeated near encounters with three of the Jovian satellites. The data handling involved in the image processing is discussed, and it is shown that only minimal processing is required for the majority of images for a Jupiter orbiter mission.

Robustness of mission plans for unmanned aircraft

NASA Astrophysics Data System (ADS)

Niendorf, Moritz

This thesis studies the robustness of optimal mission plans for unmanned aircraft. Mission planning typically involves tactical planning and path planning. Tactical planning refers to task scheduling and in multi aircraft scenarios also includes establishing a communication topology. Path planning refers to computing a feasible and collision-free trajectory. For a prototypical mission planning problem, the traveling salesman problem on a weighted graph, the robustness of an optimal tour is analyzed with respect to changes to the edge costs. Specifically, the stability region of an optimal tour is obtained, i.e., the set of all edge cost perturbations for which that tour is optimal. The exact stability region of solutions to variants of the traveling salesman problems is obtained from a linear programming relaxation of an auxiliary problem. Edge cost tolerances and edge criticalities are derived from the stability region. For Euclidean traveling salesman problems, robustness with respect to perturbations to vertex locations is considered and safe radii and vertex criticalities are introduced. For weighted-sum multi-objective problems, stability regions with respect to changes in the objectives, weights, and simultaneous changes are given. Most critical weight perturbations are derived. Computing exact stability regions is intractable for large instances. Therefore, tractable approximations are desirable. The stability region of solutions to relaxations of the traveling salesman problem give under approximations and sets of tours give over approximations. The application of these results to the two-neighborhood and the minimum 1-tree relaxation are discussed. Bounds on edge cost tolerances and approximate criticalities are obtainable likewise. A minimum spanning tree is an optimal communication topology for minimizing the cumulative transmission power in multi aircraft missions. The stability region of a minimum spanning tree is given and tolerances, stability balls, and criticalities are derived. This analysis is extended to Euclidean minimum spanning trees. This thesis aims at enabling increased mission performance by providing means of assessing the robustness and optimality of a mission and methods for identifying critical elements. Examples of the application to mission planning in contested environments, cargo aircraft mission planning, multi-objective mission planning, and planning optimal communication topologies for teams of unmanned aircraft are given.

High Leverage Technologies for In-Space Assembly of Complex Structures

NASA Technical Reports Server (NTRS)

Hamill, Doris; Bowman, Lynn M.; Belvin, W. Keith; Gilman, David A.

2016-01-01

In-space assembly (ISA), the ability to build structures in space, has the potential to enable or support a wide range of advanced mission capabilities. Many different individual assembly technologies would be needed in different combinations to serve many mission concepts. The many-to-many relationship between mission needs and technologies makes it difficult to determine exactly which specific technologies should receive priority for development and demonstration. Furthermore, because enabling technologies are still immature, no realistic, near-term design reference mission has been described that would form the basis for flowing down requirements for such development and demonstration. This broad applicability without a single, well-articulated mission makes it difficult to advance the technology all the way to flight readiness. This paper reports on a study that prioritized individual technologies across a broad field of possible missions to determine priority for future technology investment.

A low energy ion beam facility for mass spectrometer calibration: First results

NASA Astrophysics Data System (ADS)

Meyer, Stefan; Tulej, Marek; Wurz, Peter

2018-01-01

The exploration of habitable environments around the gas giants in the Solar System is of major interest in upcoming planetary missions. Exactly this theme is addressed by the Jupiter Icy Moons Explorer (JUICE) mission of the European Space Agency (ESA), which will characterise Ganymede, Europa, and Callisto as planetary objects and potential habitats. The NIM, Neutral gas and Ion Mass spectrometer, is part of the PEP experiment and will be used to measure the chemical composition of the exospheres of the icy Jovian moons. We designed and developed a calibration facility (SATANS, Supersonic cATion and ANion Source), especially for use with the NIM instrument. In a first step, we established a low energy ion beam for positive ions in the range of 0.01-30 eV. Then we conducted beam velocity calibrations with a velocity uncertainty <5%, which provided exact settings and formulas for the cation beam velocity of different gas mixtures in the range of 1-15 km/s. In addition, first results are obtained by using the NIM prototype for direct ion beam measurements under realistic JUICE mission conditions, i.e., for velocities from 1 up to 7 km/s and even more.

“One code to find them all”: a perl tool to conveniently parse RepeatMasker output files

PubMed Central

2014-01-01

Background Of the different bioinformatic methods used to recover transposable elements (TEs) in genome sequences, one of the most commonly used procedures is the homology-based method proposed by the RepeatMasker program. RepeatMasker generates several output files, including the .out file, which provides annotations for all detected repeats in a query sequence. However, a remaining challenge consists of identifying the different copies of TEs that correspond to the identified hits. This step is essential for any evolutionary/comparative analysis of the different copies within a family. Different possibilities can lead to multiple hits corresponding to a unique copy of an element, such as the presence of large deletions/insertions or undetermined bases, and distinct consensus corresponding to a single full-length sequence (like for long terminal repeat (LTR)-retrotransposons). These possibilities must be taken into account to determine the exact number of TE copies. Results We have developed a perl tool that parses the RepeatMasker .out file to better determine the number and positions of TE copies in the query sequence, in addition to computing quantitative information for the different families. To determine the accuracy of the program, we tested it on several RepeatMasker .out files corresponding to two organisms (Drosophila melanogaster and Homo sapiens) for which the TE content has already been largely described and which present great differences in genome size, TE content, and TE families. Conclusions Our tool provides access to detailed information concerning the TE content in a genome at the family level from the .out file of RepeatMasker. This information includes the exact position and orientation of each copy, its proportion in the query sequence, and its quality compared to the reference element. In addition, our tool allows a user to directly retrieve the sequence of each copy and obtain the same detailed information at the family level when a local library with incomplete TE class/subclass information was used with RepeatMasker. We hope that this tool will be helpful for people working on the distribution and evolution of TEs within genomes.

A review of some exact solutions to the planar equations of motion of a thrusting spacecraft

NASA Technical Reports Server (NTRS)

Petropoulos, A. E.; Sims, J. A.

2002-01-01

With the complexities in computing optimal low thrust trajectories, easily-computed, good sub-optimal trajectories provide both a practical alternative for mission designers and a starting point for optimisation. The present paper collects in one place for easy reference and comparison several exact solutions that have been obtained in the literature over the last few decades: the logarithmic spiral, Pinkham's variant thereof, Forbes spiral, the exponential sinusoid, the case of constant radial thrust, Markopoulos's Keplerian thrust arcs, Lawden's spiral, and the analogous Bishop and Azimov spiral.

Experiment K-7-22: Growth Hormone Regulation Synthesis and Secretion in Microgravity. Part 1; Growth Hormone Regulation Synthesis and Secretion in Microgravity

NASA Technical Reports Server (NTRS)

Hymer, W. C.; Grindeland, R.; Vale, W.; Sawchenko, P.; Ilyina-Kakueva, E. I.

1994-01-01

Changes in the musculoskeletal, immune, vascular, and endocrine system of the rat occur as a result of short-term spaceflight. Since pituitary gland growth hormone (GH) plays a role in the control of these systems, and since the results of an earlier spaceflight mission (Spacelab 3, 1985) showed that GH cell function was compromised in a number of post-flight tests, we repeated and extended the 1985 experiment in two subsequent spaceflights: the 12.5 day mission of Cosmos 1887 (in 1987) and the 14 day mission of Cosmos 2044 (in 1989). The results of these later two flight experiments are the subject of this report. They document repeatable and significant changes in the GH cell system of the spaceflown rat in several post-flight tests.

The Comet Radar Explorer Mission

NASA Astrophysics Data System (ADS)

Asphaug, Erik; Belton, Mike; Bockelee-Morvan, Dominique; Chesley, Steve; Delbo, Marco; Farnham, Tony; Gim, Yonggyu; Grimm, Robert; Herique, Alain; Kofman, Wlodek; Oberst, Juergen; Orosei, Roberto; Piqueux, Sylvain; Plaut, Jeff; Robinson, Mark; Sava, Paul; Heggy, Essam; Kurth, William; Scheeres, Dan; Denevi, Brett; Turtle, Elizabeth; Weissman, Paul

2014-11-01

Missions to cometary nuclei have revealed major geological surprises: (1) Global scale layers - do these persist through to the interior? Are they a record of primary accretion? (2) Smooth regions - are they landslides originating on the surface? Are they cryovolcanic? (3) Pits - are they impact craters or sublimation pits, or rooted in the interior? Unambiguous answers to these and other questions can be obtained by high definition 3D radar reflection imaging (RRI) of internal structure. RRI can answer many of the great unknowns in planetary science: How do primitive bodies accrete? Are cometary nuclei mostly ice? What drives their spectacular activity and evolution? The Comet Radar Explorer (CORE) mission will image the detailed internal structure of the nucleus of 10P/Tempel 2. This ~16 x 8 x 7 km Jupiter Family Comet (JFC), or its parent body, originated in the outer planets region possibly millions of years before planet formation. CORE arrives post-perihelion and observes the comet’s waning activity from safe distance. Once the nucleus is largely dormant, the spacecraft enters a ~20-km dedicated Radar Mapping Orbit (RMO). The exacting design of the RRI experiment and the precise navigation of RMO will achieve a highly focused 3D radar reflection image of internal structure, to tens of meters resolution, and tomographic images of velocity and attenuation to hundreds of meters resolution, tied to the gravity model and shape. Visible imagers will produce maps of the surface morphology, albedo, color, texture, and photometric response, and images for navigation and shape determination. The cameras will also monitor the structure and dynamics of the coma, and its dusty jets, allowing their correlation in 3D with deep interior structures and surface features. Repeated global high-resolution thermal images will probe the near-surface layers heated by the Sun. Derived maps of thermal inertia will be correlated with the radar boundary response, and photometry and texture, probing surface materials attainable by future robotic excavation missions. Thermal images will reveal areas of sublimation cooling around vents and pits, and the secular response of the outer meters as the nucleus moves farther from the Sun.

Advantages of a Modular Mars Surface Habitat Approach

NASA Technical Reports Server (NTRS)

Rucker, Michelle A.; Hoffman, Stephan J.; Andrews, Alida; Watts, Kevin

2018-01-01

Early crewed Mars mission concepts developed by the National Aeronautics and Space Administration (NASA) assumed a single, large habitat would house six crew members for a 500-day Mars surface stay. At the end of the first mission, all surface equipment, including the habitat, -would be abandoned and the process would be repeated at a different Martian landing site. This work was documented in a series of NASA publications culminating with the Mars Design Reference Mission 5.0 (NASA-SP-2009-566). The Evolvable Mars Campaign (EMC) explored whether re-using surface equipment at a single landing site could be more affordable than the Apollo-style explore-abandon-repeat mission cadence. Initial EMC assumptions preserved the single, monolithic habitat, the only difference being a new requirement to reuse the surface habitat for multiple expedition crews. A trade study comparing a single large habitat versus smaller, modular habitats leaned towards the monolithic approach as more mass-efficient. More recent work has focused on the operational aspects of building up Mars surface infrastructure over multiple missions, and has identified compelling advantages of the modular approach that should be considered before making a final decision. This paper explores Mars surface mission operational concepts and integrated system analysis, and presents an argument for the modular habitat approach.

Tensor network method for reversible classical computation

NASA Astrophysics Data System (ADS)

Yang, Zhi-Cheng; Kourtis, Stefanos; Chamon, Claudio; Mucciolo, Eduardo R.; Ruckenstein, Andrei E.

2018-03-01

We develop a tensor network technique that can solve universal reversible classical computational problems, formulated as vertex models on a square lattice [Nat. Commun. 8, 15303 (2017), 10.1038/ncomms15303]. By encoding the truth table of each vertex constraint in a tensor, the total number of solutions compatible with partial inputs and outputs at the boundary can be represented as the full contraction of a tensor network. We introduce an iterative compression-decimation (ICD) scheme that performs this contraction efficiently. The ICD algorithm first propagates local constraints to longer ranges via repeated contraction-decomposition sweeps over all lattice bonds, thus achieving compression on a given length scale. It then decimates the lattice via coarse-graining tensor contractions. Repeated iterations of these two steps gradually collapse the tensor network and ultimately yield the exact tensor trace for large systems, without the need for manual control of tensor dimensions. Our protocol allows us to obtain the exact number of solutions for computations where a naive enumeration would take astronomically long times.

Future space transportation systems analysis study. Phase 1: Technical report, appendices. [a discussion of orbit transfer vehicles, lunar transport vehicles, space shuttles, and reusable spacecraft

NASA Technical Reports Server (NTRS)

1975-01-01

The transportation mass requirements developed for each mission and transportation mode were based on vehicle systems sized to fit the exact needs of each mission (i.e. rubber vehicles). The parametric data used to derive the mass requirements for each mission and transportation mode are presented to enable accommodation of possible changes in mode options or payload definitions. The vehicle sizing and functional requirements used to derive the parametric data will form the basis for conceptual configurations of the transportation elements in a later phase of study. An investigation of the weight growth approach to future space transportation systems analysis is presented. Parameters which affect weight growth, past weight histories, and the current state of future space-mission design are discussed. Weight growth factors of from 10 percent to 41 percent were derived for various missions or vehicles.

Robotic Exploration: The Role of Science Autonomy

NASA Technical Reports Server (NTRS)

Roush, Ted L.; DeVincenzi, D. (Technical Monitor)

2002-01-01

Historical mission operations have involved: (1) commands transmitted to the craft; (2) execution of commands; (3) return of scientific data; (4) evaluation of these data by scientists; and (5) recommendations for future mission activity by scientists. This cycle is repeated throughout the mission with command opportunities once or twice per day. For a rover, this historical cycle is not amenable to rapid long range traverses or rapid response to any novel or unexpected situations.

Interactive mission planning for a Space Shuttle flight experiment - A case history

NASA Technical Reports Server (NTRS)

Harris, H. M.

1986-01-01

Scientific experiments which use the Space Shuttle as a platform require the development of new operations techniques for the command and control of the instrument. Principal among these is the ability to simulate the complex maneuvers of the orbiter's path realistically. Computer generated graphics provide a window into the actual and predicted performance of the instrument and allow sophisticated control of the instrument under varying conditions. In October of 1984 the Shuttle carried a synthetic aperture radar built by JPL for the purpose of recording images of the earth surface. The mission deviated from planned operation in almost every conceivable way and provided an exacting test bed for concepts of interactive mission planning.

Choral Warm-Ups for Changing Adolescent Voices

ERIC Educational Resources Information Center

Freer, Patirck K.

2009-01-01

During two decades of observing and leading middle school choral rehearsals, the author has observed that teachers frequently repeat exactly the warm-ups they present to their young adolescent choirs at every rehearsal. If teachers know one thing about middle school students, they know that they are constantly changing--physically, intellectually,…

Rapid, Repeat-sample Monitoring of Crustal Deformations and Environmental Phenomena with the Uninhabited Aerial Vehicle Synthetic Aperture Radar

NASA Technical Reports Server (NTRS)

Smith, Robert C.

2006-01-01

The Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) is a precision repeat-pass Interferometric Synthetic Aperture Radar (InSAR) mission being developed by the Jet Propulsion Laboratory and the Dryden Flight Research Center in support of NASA s Science Mission Directorate. UAVSAR's unique ability to fly a repeatable flight path, along with an electronically steerable array, allows interferometric data to be obtained with accuracies measured in millimeters. Deploying the radar on an airborne platform will also allow for radar images to be collected and compared with images from the same area taken hours or even years later - providing for long-term trending and near real-time notification of changes and deformations. UAVSAR s data processing algorithms will provide for near-real time data reduction providing disaster planning and response teams with highly accurate data to aid in the prediction of, and response to, natural phenomena. UAVSAR data can be applied to increasing our understanding of the processes behind solid earth, cryosphere, carbon cycle and other areas of interest in earth science. Technologies developed for UAVSAR may also be applicable to a future earth-orbiting InSAR mission and possibly for missions to the Moon or Mars. The UAVSAR is expected to fly on a Gulfstream III aircraft this winter, followed by a flight test program lasting until the second half of 2007. Following radar calibration and data reduction activities, the platform will be ready for science users in the summer of 2008.

Human physiological benefits of viewing nature: EEG responses to exact and statistical fractal patterns.

PubMed

Hagerhall, C M; Laike, T; Küller, M; Marcheschi, E; Boydston, C; Taylor, R P

2015-01-01

Psychological and physiological benefits of viewing nature have been extensively studied for some time. More recently it has been suggested that some of these positive effects can be explained by nature's fractal properties. Virtually all studies on human responses to fractals have used stimuli that represent the specific form of fractal geometry found in nature, i.e. statistical fractals, as opposed to fractal patterns which repeat exactly at different scales. This raises the question of whether human responses like preference and relaxation are being driven by fractal geometry in general or by the specific form of fractal geometry found in nature. In this study we consider both types of fractals (statistical and exact) and morph one type into the other. Based on the Koch curve, nine visual stimuli were produced in which curves of three different fractal dimensions evolve gradually from an exact to a statistical fractal. The patterns were shown for one minute each to thirty-five subjects while qEEG was continuously recorded. The results showed that the responses to statistical and exact fractals differ, and that the natural form of the fractal is important for inducing alpha responses, an indicator of a wakefully relaxed state and internalized attention.

Processing new and repeated names: Effects of coreference on repetition priming with speech and fast RSVP

PubMed Central

Camblin, C. Christine; Ledoux, Kerry; Boudewyn, Megan; Gordon, Peter C.; Swaab, Tamara Y.

2006-01-01

Previous research has shown that the process of establishing coreference with a repeated name can affect basic repetition priming. Specifically, repetition priming on some measures can be eliminated for repeated names that corefer with an entity that is prominent in the discourse model. However, the exact nature and timing of this modulating effect of discourse are not yet understood. Here, we present two ERP studies that further probe the nature of repeated name coreference by using naturally produced connected speech and fast-rate RSVP methods of presentation. With speech we found that repetition priming was eliminated for repeated names that coreferred with a prominent antecedent. In contrast, with fast-rate RSVP, we found a main effect of repetition that did not interact with sentence context. This indicates that the creation of a discourse model during comprehension can affect repetition priming, but the nature of this effect may depend on input speed. PMID:16904078

Design Considerations for a Dedicated Gravity Recovery Satellite Mission Consisting of Two Pairs of Satellites

NASA Technical Reports Server (NTRS)

Wiese, D. N.; Nerem, R. S.; Lemoine, F. G.

2011-01-01

Future satellite missions dedicated to measuring time-variable gravity will need to address the concern of temporal aliasing errors; i.e., errors due to high-frequency mass variations. These errors have been shown to be a limiting error source for future missions with improved sensors. One method of reducing them is to fly multiple satellite pairs, thus increasing the sampling frequency of the mission. While one could imagine a system architecture consisting of dozens of satellite pairs, this paper explores the more economically feasible option of optimizing the orbits of two pairs of satellites. While the search space for this problem is infinite by nature, steps have been made to reduce it via proper assumptions regarding some parameters and a large number of numerical simulations exploring appropriate ranges for other parameters. A search space originally consisting of 15 variables is reduced to two variables with the utmost impact on mission performance: the repeat period of both pairs of satellites (shown to be near-optimal when they are equal to each other), as well as the inclination of one of the satellite pairs (the other pair is assumed to be in a polar orbit). To arrive at this conclusion, we assume circular orbits, repeat groundtracks for both pairs of satellites, a 100-km inter-satellite separation distance, and a minimum allowable operational satellite altitude of 290 km based on a projected 10-year mission lifetime. Given the scientific objectives of determining time-variable hydrology, ice mass variations, and ocean bottom pressure signals with higher spatial resolution, we find that an optimal architecture consists of a polar pair of satellites coupled with a pair inclined at 72deg, both in 13-day repeating orbits. This architecture provides a 67% reduction in error over one pair of satellites, in addition to reducing the longitudinal striping to such a level that minimal post-processing is required, permitting a substantial increase in the spatial resolution of the gravity field products. It should be emphasized that given different sets of scientific objectives for the mission, or a different minimum allowable satellite altitude, different architectures might be selected.

Design of the VISITOR Tool: A Versatile ImpulSive Interplanetary Trajectory OptimizeR

NASA Technical Reports Server (NTRS)

Corpaccioli, Luca; Linskens, Harry; Komar, David R.

2014-01-01

The design of trajectories for interplanetary missions represents one of the most complex and important problems to solve during conceptual space mission design. To facilitate conceptual mission sizing activities, it is essential to obtain sufficiently accurate trajectories in a fast and repeatable manner. To this end, the VISITOR tool was developed. This tool modularly augments a patched conic MGA-1DSM model with a mass model, launch window analysis, and the ability to simulate more realistic arrival and departure operations. This was implemented in MATLAB, exploiting the built-in optimization tools and vector analysis routines. The chosen optimization strategy uses a grid search and pattern search, an iterative variable grid method. A genetic algorithm can be selectively used to improve search space pruning, at the cost of losing the repeatability of the results and increased computation time. The tool was validated against seven flown missions: the average total mission (Delta)V offset from the nominal trajectory was 9.1%, which was reduced to 7.3% when using the genetic algorithm at the cost of an increase in computation time by a factor 5.7. It was found that VISITOR was well-suited for the conceptual design of interplanetary trajectories, while also facilitating future improvements due to its modular structure.

Using a dynamical advection to reconstruct a part of the SSH evolution in the context of SWOT, application to the Mediterranean Sea

NASA Astrophysics Data System (ADS)

Rogé, Marine; Morrow, Rosemary; Ubelmann, Clément; Dibarboure, Gérald

2017-08-01

The main oceanographic objective of the future SWOT mission is to better characterize the ocean mesoscale and sub-mesoscale circulation, by observing a finer range of ocean topography dynamics down to 20 km wavelength. Despite the very high spatial resolution of the future satellite, it will not capture the time evolution of the shorter mesoscale signals, such as the formation and evolution of small eddies. SWOT will have an exact repeat cycle of 21 days, with near repeats around 5-10 days, depending on the latitude. Here, we investigate a technique to reconstruct the missing 2D SSH signal in the time between two satellite revisits. We use the dynamical interpolation (DI) technique developed by Ubelmann et al. (2015). Based on potential vorticity (hereafter PV) conservation using a one and a half layer quasi-geostrophic model, it features an active advection of the SSH field. This model has been tested in energetic open ocean regions such as the Gulf Stream and the Californian Current, and has given promising results. Here, we test this model in the Western Mediterranean Sea, a lower energy region with complex small scale physics, and compare the SSH reconstruction with the high-resolution Symphonie model. We investigate an extension of the simple dynamical model including a separated mean circulation. We find that the DI gives a 16-18% improvement in the reconstruction of the surface height and eddy kinetic energy fields, compared with a simple linear interpolation, and a 37% improvement in the Northern Current subregion. Reconstruction errors are higher during winter and autumn but statistically, the improvement from the DI is also better for these seasons.

Repeat Gamma-Knife Radiosurgery for Refractory or Recurrent Trigeminal Neuralgia with Consideration About the Optimal Second Dose.

PubMed

Park, Seong-Cheol; Kwon, Do Hoon; Lee, Do Hee; Lee, Jung Kyo

2016-02-01

To investigate adequate radiation doses for repeat Gamma Knife radiosurgery (GKS) for trigeminal neuralgia in our series and meta-analysis. Fourteen patients treated by ipsilateral repeat GKS for trigeminal neuralgia were included. Median age of patients was 65 years (range, 28-78), the median target dose, 140-180). Patients were followed a median of 10.8 months (range, 1-151) after the second gamma-knife surgery. Brainstem dose analysis and vote-counting meta-analysis of 19 studies were performed. After the second gamma-knife radiosurgeries, pain was relieved effectively in 12 patients (86%; Barrow Neurological Institute Pain Intensity Score I-III). Post-gamma-knife radiosurgery trigeminal nerve deficits were mild in 5 patients. No serious anesthesia dolorosa was occurred. The second GKS radiation dose ≤ 60 Gy was significantly associated with worse pain control outcome (P = 0.018 in our series, permutation analysis of variance, and P = 0.009 in the meta-analysis, 2-tailed Fisher's exact test). Cumulative dose ≤ 140-150 Gy was significantly associated with poor pain control outcome (P = 0.033 in our series and P = 0.013 in the meta-analysis, 2-tailed Fisher's exact test). A cumulative brainstem edge dose >12 Gy tended to be associated with trigeminal nerve deficit (P = 0.077). Our study suggests that the second GKS dose is a potentially important factor. Copyright © 2016 Elsevier Inc. All rights reserved.

Immediate Small Number Perception : Evidence from a New Numerical Carry-Over Procedure

ERIC Educational Resources Information Center

Demeyere, Nele; Humphreys, Glyn W.

2012-01-01

Evidence is presented for the immediate apprehension of exact small quantities. Participants performed a quantification task (are the number of items greater or smaller than?), and carry-over effects were examined between numbers requiring the same response. Carry-over effects between small numbers were strongly affected by repeats of pattern and…

Estimating a Meaningful Point of Change: A Comparison of Exploratory Techniques Based on Nonparametric Regression

ERIC Educational Resources Information Center

Klotsche, Jens; Gloster, Andrew T.

2012-01-01

Longitudinal studies are increasingly common in psychological research. Characterized by repeated measurements, longitudinal designs aim to observe phenomena that change over time. One important question involves identification of the exact point in time when the observed phenomena begin to meaningfully change above and beyond baseline…

Reducing the Risk of Suicide in Patients with Bipolar Disorder: Interventions and Safeguards

ERIC Educational Resources Information Center

Newman, Cory F.

2005-01-01

Bipolar disorder exacts a terrible toll on its sufferers owing to the repeated, severe disruptions in the patients' lives, the discomfort and uncertainties of being on rigorous, ongoing pharmacotherapy regimens, the emotional difficulties inherent in experiencing depression and mania, and the fear of a deteriorating course. Patients with bipolar…

Simulation of Crack Propagation in Engine Rotating Components under Variable Amplitude Loading

NASA Technical Reports Server (NTRS)

Bonacuse, P. J.; Ghosn, L. J.; Telesman, J.; Calomino, A. M.; Kantzos, P.

1998-01-01

The crack propagation life of tested specimens has been repeatedly shown to strongly depend on the loading history. Overloads and extended stress holds at temperature can either retard or accelerate the crack growth rate. Therefore, to accurately predict the crack propagation life of an actual component, it is essential to approximate the true loading history. In military rotorcraft engine applications, the loading profile (stress amplitudes, temperature, and number of excursions) can vary significantly depending on the type of mission flown. To accurately assess the durability of a fleet of engines, the crack propagation life distribution of a specific component should account for the variability in the missions performed (proportion of missions flown and sequence). In this report, analytical and experimental studies are described that calibrate/validate the crack propagation prediction capability ]or a disk alloy under variable amplitude loading. A crack closure based model was adopted to analytically predict the load interaction effects. Furthermore, a methodology has been developed to realistically simulate the actual mission mix loading on a fleet of engines over their lifetime. A sequence of missions is randomly selected and the number of repeats of each mission in the sequence is determined assuming a Poisson distributed random variable with a given mean occurrence rate. Multiple realizations of random mission histories are generated in this manner and are used to produce stress, temperature, and time points for fracture mechanics calculations. The result is a cumulative distribution of crack propagation lives for a given, life limiting, component location. This information can be used to determine a safe retirement life or inspection interval for the given location.

CubeSat on an Earth-Mars Free-Return Trajectory to study radiation hazards in the future manned mission

NASA Astrophysics Data System (ADS)

Vannitsen, J.; Segret, B.; Miau, J. J.; Juang, J.-C.

2013-09-01

In order to prepare the Human Mission to Mars, few aspects of the mission still have to be known. During a transit to the Red Planet, future crews will be exposed to potentially hazardous radiations [1]. By using a CubeSat, we can then have a relatively cheap and easy way to improve the radiations environment knowledge for a Mars manned mission. A 1 Unit CubeSat is a type of miniaturized satellite for space research that usually has a volume of exactly one litre (10 cm cube), has a mass of no more than 1.33 kilograms and typically uses commercial off-the-shelf components for its electronics [2]. In this project, it is planned to use a 3 Unit CubeSat having the following dimensions: 10 cm x 10 cm x 30 cm and a maximum mass of 4kg.

MPD Thruster Performance Analytic Models

NASA Technical Reports Server (NTRS)

Gilland, James; Johnston, Geoffrey

2003-01-01

Magnetoplasmadynamic (MPD) thrusters are capable of accelerating quasi-neutral plasmas to high exhaust velocities using Megawatts (MW) of electric power. These characteristics make such devices worthy of consideration for demanding, far-term missions such as the human exploration of Mars or beyond. Assessment of MPD thrusters at the system and mission level is often difficult due to their status as ongoing experimental research topics rather than developed thrusters. However, in order to assess MPD thrusters utility in later missions, some adequate characterization of performance, or more exactly, projected performance, and system level definition are required for use in analyses. The most recent physical models of self-field MPD thrusters have been examined, assessed, and reconfigured for use by systems and mission analysts. The physical models allow for rational projections of thruster performance based on physical parameters that can be measured in the laboratory. The models and their implications for the design of future MPD thrusters are presented.

MPD Thruster Performance Analytic Models

NASA Technical Reports Server (NTRS)

Gilland, James; Johnston, Geoffrey

2007-01-01

Magnetoplasmadynamic (MPD) thrusters are capable of accelerating quasi-neutral plasmas to high exhaust velocities using Megawatts (MW) of electric power. These characteristics make such devices worthy of consideration for demanding, far-term missions such as the human exploration of Mars or beyond. Assessment of MPD thrusters at the system and mission level is often difficult due to their status as ongoing experimental research topics rather than developed thrusters. However, in order to assess MPD thrusters utility in later missions, some adequate characterization of performance, or more exactly, projected performance, and system level definition are required for use in analyses. The most recent physical models of self-field MPD thrusters have been examined, assessed, and reconfigured for use by systems and mission analysts. The physical models allow for rational projections of thruster performance based on physical parameters that can be measured in the laboratory. The models and their implications for the design of future MPD thrusters are presented.

New primer for specific amplification of the CAG repeat in Huntington disease alleles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bond, C.E.; Hodes, M.E.

1994-09-01

Huntington disease is an autosomal dominant neurodegenerative disorder caused by an expansion of a CAG trinucleotide repeat near the 5{prime} end of the gene for Huntington disease (IT15). The CAG repeat is flanked by a variable-length CCG repeat that is included in the amplification product obtained with most currently used primer sets and PCR protocols. Inclusion of this adjacent CCG repeat complicates the accurate assessment of CAG repeat length and interferes with the genotype determination of those individuals carrying alleles in the intermediate range between normal and expanded sized. Due to the GC-rich nature of this region, attempts at designingmore » a protocol for amplification of only the CAG repeat have proved unreliable and difficult to execute. We report here the development of a compatible primer set and PCR protocol that yields consistent amplification of the CAG-repeat region. PCR products can be visualized in ethidium bromide-stained agarose gels for rapid screening or in 6% polyacrylamide gels for determination of exact repeat length. This assay produces bands that can be sized accurately, while eliminating most nonspecific products. Fifty-five specimens examined showed consistency with another well-known method, but one that amplifies the CCG repeats as well. The results we obtained also matched the known carrier status of the donors.« less

JPL-20170811-CASSINf-0001a-A World Unveiled Cassini at TItan

NASA Image and Video Library

2017-08-11

A look at the Cassini-Huygens mission's discoveries at Saturn's moon Titan and a description of how flybys of Titan allowed the mission to change to new orbits repeatedly without wasting fuel. Featuring Linda Spilker, Cassini Project Scientist, JPL; Jonathan Lunine, Cassini Titan Scientist, Cornell University; and Elizabeth "Zibi" Turtle, Cassini Imaging Team, John Hopkins Applied Physics Laboratory.

The Ohio State 1991 geopotential and sea surface topography harmonic coefficient models

NASA Technical Reports Server (NTRS)

Rapp, Richard H.; Wang, Yan Ming; Pavlis, Nikolaos K.

1991-01-01

The computation is described of a geopotential model to deg 360, a sea surface topography model to deg 10/15, and adjusted Geosat orbits for the first year of the exact repeat mission (ERM). This study started from the GEM-T2 potential coefficient model and it's error covariance matrix and Geosat orbits (for 22 ERMs) computed by Haines et al. using the GEM-T2 model. The first step followed the general procedures which use a radial orbit error theory originally developed by English. The Geosat data was processed to find corrections to the a priori geopotential model, corrections to a radial orbit error model for 76 Geosat arcs, and coefficients of a harmonic representation of the sea surface topography. The second stage of the analysis took place by doing a combination of the GEM-T2 coefficients with 30 deg gravity data derived from surface gravity data and anomalies obtained from altimeter data. The analysis has shown how a high degree spherical harmonic model can be determined combining the best aspects of two different analysis techniques. The error analysis was described that has led to the accuracy estimates for all the coefficients to deg 360. Significant work is needed to improve the modeling effort.

Crewmember Performance Before, During, And After Spaceflight

PubMed Central

Kelly, Thomas H; Hienz, Robert D; Zarcone, Troy J; Wurster, Richard M; Brady, Joseph V

2005-01-01

The development of technologies for monitoring the welfare of crewmembers is a critical requirement for extended spaceflight. Behavior analytic methodologies provide a framework for studying the performance of individuals and groups, and brief computerized tests have been used successfully to examine the impairing effects of sleep, drug, and nutrition manipulations on human behavior. The purpose of the present study was to evaluate the feasibility and sensitivity of repeated performance testing during spaceflight. Four National Aeronautics and Space Administration crewmembers were trained to complete computerized questionnaires and performance tasks at repeated regular intervals before and after a 10-day shuttle mission and at times that interfered minimally with other mission activities during spaceflight. Two types of performance, Digit-Symbol Substitution trial completion rates and response times during the most complex Number Recognition trials, were altered slightly during spaceflight. All other dimensions of the performance tasks remained essentially unchanged over the course of the study. Verbal ratings of Fatigue increased slightly during spaceflight and decreased during the postflight test sessions. Arousal ratings increased during spaceflight and decreased postflight. No other consistent changes in rating-scale measures were observed over the course of the study. Crewmembers completed all mission requirements in an efficient manner with no indication of clinically significant behavioral impairment during the 10-day spaceflight. These results support the feasibility and utility of computerized task performances and questionnaire rating scales for repeated measurement of behavior during spaceflight. PMID:16262187

Exact Schwarzschild-like solution in a bumblebee gravity model

NASA Astrophysics Data System (ADS)

Casana, R.; Cavalcante, A.; Poulis, F. P.; Santos, E. B.

2018-05-01

We obtain an exact vacuum solution from the gravity sector contained in the minimal standard-model extension. The theoretical model assumes a Riemann spacetime coupled to the bumblebee field which is responsible for the spontaneous Lorentz symmetry breaking. The solution achieved in a static and spherically symmetric scenario establishes a Schwarzschild-like black hole. In order to study the effects of the spontaneous Lorentz symmetry breaking we investigate some classic tests, including the advance of perihelion, the bending of light, and Shapiro's time delay. Furthermore, we compute some upper bounds, among which the most stringent associated with existing experimental data provides a sensitivity at the 10-15 level and that for future missions at the 10-19 level.

Statistics provide guidance for indigenous organic carbon detection on Mars missions.

PubMed

Sephton, Mark A; Carter, Jonathan N

2014-08-01

Data from the Viking and Mars Science Laboratory missions indicate the presence of organic compounds that are not definitively martian in origin. Both contamination and confounding mineralogies have been suggested as alternatives to indigenous organic carbon. Intuitive thought suggests that we are repeatedly obtaining data that confirms the same level of uncertainty. Bayesian statistics may suggest otherwise. If an organic detection method has a true positive to false positive ratio greater than one, then repeated organic matter detection progressively increases the probability of indigeneity. Bayesian statistics also reveal that methods with higher ratios of true positives to false positives give higher overall probabilities and that detection of organic matter in a sample with a higher prior probability of indigenous organic carbon produces greater confidence. Bayesian statistics, therefore, provide guidance for the planning and operation of organic carbon detection activities on Mars. Suggestions for future organic carbon detection missions and instruments are as follows: (i) On Earth, instruments should be tested with analog samples of known organic content to determine their true positive to false positive ratios. (ii) On the mission, for an instrument with a true positive to false positive ratio above one, it should be recognized that each positive detection of organic carbon will result in a progressive increase in the probability of indigenous organic carbon being present; repeated measurements, therefore, can overcome some of the deficiencies of a less-than-definitive test. (iii) For a fixed number of analyses, the highest true positive to false positive ratio method or instrument will provide the greatest probability that indigenous organic carbon is present. (iv) On Mars, analyses should concentrate on samples with highest prior probability of indigenous organic carbon; intuitive desires to contrast samples of high prior probability and low prior probability of indigenous organic carbon should be resisted.

Swift Gamma-Ray Burst Explorer: Mission Design for Rapid, Accurate Location of Gamma-ray Bursts

NASA Technical Reports Server (NTRS)

Bundas, David J.

2004-01-01

The Swift Gamma-ray Burst Explorer is a NASA Mid-sized Explorer (MIDEX) with the primary mission of determining the origins of Gamma-Ray Bursts (GRBs). It will be the first mission to autonomously respond to newly-discovered GRBs and provide immediate follow-up with narrow field instruments capable of multi-wavelength (UV, Optical, X-ray) observations. The characteristics of GRBs that are the key mission design drivers, are their non-repeating and brief duration bursts of multi-wavelength photons. In addition, rapid notification of the location and characteristics of the GRBs to ground-and-space-based observatories drive the end-to-end data analysis and distribution requirements.

Swift Gamma-ray Burst Explorer: Mission Design for Rapid, Accurate Location of Gamma-ray Bursts

NASA Technical Reports Server (NTRS)

Bundas, David J.

2005-01-01

The Swift Gamma-ray Burst Explorer is a NASA Mid-sized Explorer (MIDEX) with the primary mission of determining the origins of Gamma-Ray Bursts (GRBs). It will be the first mission to autonomously respond to newly-discovered GRBs and provide immediate follow-up with narrow field instruments capable of multi-wavelength (UT, Optical, X-ray) observations. The characteristics of GRBs that are the key mission design drivers, are their non-repeating and brief duration bursts of multi-wavelength photons. In addition, rapid notification of the location and characteristics of the GRBs to ground-and-space-based observatories drive the end-to-end data analysis and distribution requirements.

Cryogenic Propulsion Stage (CPS) Configuration in Support of NASA's Multiple Design Reference Missions (DRMs)

NASA Technical Reports Server (NTRS)

Hanna, Stephen G.; Jones, David L.; Creech, Stephen D.; Lawrence, Thomas D.

2012-01-01

In support of the National Aeronautics and Space Administration's (NASA) Human Exploration and Operations Mission Directorate (HEOMD), the Space Launch System (SLS) is being designed for safe, affordable, and sustainable human and scientific exploration missions beyond Earth's or-bit (BEO). The SLS Team is tasked with developing a system capable of safely and repeatedly lofting a new fleet of spaceflight vehicles beyond Earth orbit. The Cryogenic Propulsion Stage (CPS) is a key enabler for evolving the SLS capability for BEO missions. This paper reports on the methodology and initial recommendations relative to the CPS, giving a brief retrospective of early studies on this promising propulsion hardware. This paper provides an overview of the requirements development and CPS configuration in support of NASA's multiple Design Reference Missions (DRMs).

Effect of one low thinning on cove and slope hardwoods in the New Jersey highlands

Treesearch

H. B. Tepper; G. T. Bamford

1959-01-01

The exact value of thinning in managing hardwoods is not yet known. Further study of the many factors that affect thinning results is needed. These factors include methods and intensities of thinning, ages at which thinnings are started or repeated, effects of species composition in mixed stands, and influence of site index on response to thinning.

Lincoln Laboratory Journal. Volume 22, Number 1, 2016

DTIC Science & Technology

2016-06-09

needs cyber ranges and other infrastructure to conduct scal- able, repeatable, scientific, realistic and inexpensive testing, training, and mission...support this mission, infrastructure is being upgraded to make it more efficient and secure. In “Secur- ing the U.S. Transportation Command,” Jeff...using the Electronic Key Management System (EKMS) or over a digital network by using the Key Manage- ment Infrastructure (KMI). The units must then

Cytogenetic damage in the blood lymphocytes of astronauts: effects of repeat long-duration space missions.

PubMed

George, K; Rhone, J; Beitman, A; Cucinotta, F A

2013-08-30

Human missions onboard the International Space Station (ISS) are increasing in duration and several astronauts have now participated in second ISS increments. The radiation environment in space is very different from terrestrial radiation exposure and it is still unclear if space flight effects and radiation from repeat missions are simply additive, which potentially confounds the assessment of the cumulative risk of radiation exposure. It has been shown that single space missions of a few months or more on the ISS can induce measureable increases in the yield of chromosome damage in the blood lymphocytes of astronauts, and it appears that cytogenetic biodosimetry can be used reliably to estimate equivalent dose and radiation risk. We have now obtained direct in vivo measurements of chromosome damage in blood lymphocytes of five astronauts before and after their first and second long duration space flights. Chromosome damage was assessed by fluorescence in situ hybridization technique using three different chromosome painting probes. All astronauts showed an increase in total exchanges and translocations after both the first and second flight. Biological dose measured using either individual assessment or a population assessment supports an additive risk model. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

NASA and Dark Energy

NASA Astrophysics Data System (ADS)

Rhodes, Jason

2014-03-01

Dark energy, the name given to the cause of the accelerating expansion of the Universe, is one of the most profound mysteries in modern science. Current cosmological models hold that dark energy is currently the dominant component of the Universe, but the exact nature of dark energy remains poorly understood. There are ambitious ground-based surveys underway that seek to understand dark energy and NASA is participating in the development of significantly more ambitious space-based surveys planned for the next decade. NASA has provided mission enabling technology to the European Space Agency's (ESA) Euclid mission in exchange for US scientists to participate in the Euclid mission. NASA is also developing the Wide Field Infrared Survey Telescope-Astrophysics Focused Telescope Asset (WFIRST-AFTA) mission for possible launch in ~2023. WFIRST was the highest ranked space mission in the Astro2010 Decadal Survey and the AFTA incarnation of the WFIRST design uses a 2.4 m space telescope to go beyond what the Decadal Survey envisioned for WFIRST. Understanding dark energy is one of the primary science goals of WFIRST-AFTA. I'll discuss the status of Euclid and WFIRST and comment on the complementarity of the two missions.

After the Mars Polar Lander: Where to Next?

NASA Technical Reports Server (NTRS)

Paige, D. A.; Boynton, W. V.; Crisp, D.; DeJong, E.; Hansen, C. J.; Harri, A. M.; Keller, H. U.; Leshin, L. A.; May, R. D.; Smith, P. H.

2000-01-01

The recent loss of the Mars Polar Lander (MPL) mission represents a serious setback to Mars science and exploration. Targeted to land on the Martian south polar layered deposits at 76 degrees south latitude and 195 degrees west longitude, it would have been the first mission to study the geology, atmospheric environment, and volatiles at a high-latitude landing site. Since the conception of the MPL mission, a Mars exploration strategy has emerged which focuses on Climate, Resources and Life, with the behavior and history of water as the unifying theme. A successful MPL mission would have made significant contributions towards these goals, particularly in understanding the distribution and behavior of near-surface water, and the nature and climate history of the south polar layered deposits. Unfortunately, due to concerns regarding the design of the MPL spacecraft, the rarity of direct trajectories that enable high-latitude landings, and funding, an exact reflight of MPL is not feasible within the present planning horizon. However, there remains significant interest in recapturing the scientific goals of the MPL mission. The following is a discussion of scientific and strategic issues relevant to planning the next polar lander mission, and beyond.

Tektite 2 habitability research program: Day-to-day life in the habitat

NASA Technical Reports Server (NTRS)

Nowlis, D. P.

1972-01-01

Because it is widely agreed that the field of environmental psychology is quite young, it was determined that a sample of recorded observations from a representative mission should be included in the report on Tektite to give the professional reader a better feeling of normal day-to-day life in the isolated habitat. Names of the crew members have been replaced with numbers and some off-color words have been replaced by more acceptable slang; some remarks have been omitted that might lead to easy identification of the subjects. Otherwise, the following pages are exactly as transcribed during the late afternoons and the evenings of the mission.

Spacelab

NASA Image and Video Library

1985-04-01

Activities inside the laboratory module during the Spacelab-3 mission are shown in this photograph. Left to right are astronauts Robert Overmyer, Commander of the mission; Don Lind, Mission Specialist; Lodewijk van den Berg, Payload Specialist; and William Thornton, Mission Specialist. The primary purpose of the Spacelab-3 mission was to conduct materials science experiments in a stable low-gravity environment. In addition, the crew did research in life sciences, fluid mechanics, atmospheric science, and astronomy. Spacelab-3 was equipped with several new minilabs, special facilities that would be used repeatedly on future flights. Two elaborate crystal growth furnaces, a life support and housing facility for small animals, and two types of apparatus for the study of fluids were evaluated on their inaugural flight. Spacelab-3 (STS-51B) was launched aboard the Space Shuttle Challenger on April 29, 1985. The Marshall Space Flight Center had managing responsibilities of the mission.

Variable-Number Tandem Repeats That Are Useful in Genotyping Isolates of Salmonella enterica subsp. enterica Serovars Typhimurium and Newport▿

PubMed Central

Witonski, D. ; Stefanova, R.; Ranganathan, A.; Schutze, G. E.; Eisenach, K. D.; Cave, M. D.

2006-01-01

The genome of Salmonella enterica subsp. enterica serovar Typhimurium strain LT2 was analyzed for direct repeats, and 54 sequences containing variable-number tandem repeat loci were identified. Ten primer pairs that anneal upstream and downstream of each selected locus were designed and used to amplify PCR targets in isolates of S. enterica serovars Typhimurium and Newport. Four of the 10 loci did not show polymorphism in the length of products. Six loci were selected for analysis. Isolates of S. enterica serovars Typhimurium and Newport that were related to specific outbreaks and showed identical pulsed-field gel electrophoresis patterns were indistinguishable by the length of the six variable-number tandem repeats. Isolates that differed in their pulsed-field gel electrophoresis patterns showed polymorphism in variable-number tandem repeat profiles. Length of the products was confirmed by DNA sequence analysis. Only 2 of the 10 loci contained exact integers of the direct repeat. Eight loci contained partial copies. The partial copies were maintained at the ends of the variable-number tandem repeat loci in all isolates. In spite of having partial copies that were maintained in all isolates, the number of direct repeats at a locus was polymorphic. Six variable-number tandem repeat loci were useful in distinguishing isolates of S. enterica serovars Typhimurium and Newport that had different pulsed-field gel electrophoresis patterns and in identifying outbreak-associated cases that shared a common pulsed-field gel pattern. PMID:16943354

Behind the Scenes at Berkeley Lab - The Mechanical Fabrication Facility

ScienceCinema

Wells, Russell; Chavez, Pete; Davis, Curtis; Bentley, Brian

2018-04-16

Part of the Behind the Scenes series at Berkeley Lab, this video highlights the lab's mechanical fabrication facility and its exceptional ability to produce unique tools essential to the lab's scientific mission. Through a combination of skilled craftsmanship and precision equipment, machinists and engineers work with scientists to create exactly what's needed - whether it's measured in microns or meters.

Brian K. Kobilka and G-protein-coupled Receptors (GPCR)

Science.gov Websites

the laboratory's Advanced Photon Source (APS) to make the first discovery of the structure of a human the structure of β2AR at the exact moment that the protein-receptor complex signals across the carrying out its biological mission. ... In order to obtain the structure of a GPCR, Kobilka and his

Earth Observatory Satellite system definition study. Report no. 1: Orbit/launch vehicle tradeoff studies and recommendations

NASA Technical Reports Server (NTRS)

1974-01-01

A study was conducted to determine the recommended orbit for the Earth Observatory Satellite (EOS) Land Resources Mission. It was determined that a promising sun synchronous orbit is 366 nautical miles when using an instrument with a 100 nautical mile swath width. The orbit has a 17 day repeat cycle and a 14 nautical mile swath overlap. Payloads were developed for each mission, EOS A through F. For each mission, the lowest cost booster that was capable of lifting the payload to the EOS orbit was selected. The launch vehicles selected for the missions are identified on the basis of tradeoff studies and recommendations. The reliability aspects of the launch vehicles are analyzed.

Dynamic UNITY

DTIC Science & Technology

2002-01-01

UNITY program that implements exactly the same algorithm as Specification 1.1. The correctness of this program is proven in amanner sim- 4 program...chapter, we introduce the Dynamic UNITY formalism, which allows us to reason about algorithms and protocols in which the sets of participating processes...implements Euclid’s algorithm for calculating the greatest common divisor (GCD) of two integers; it repeat- edly reads an integer message from each of its

A Vision for an International Multi-Sensor Snow Observing Mission

NASA Technical Reports Server (NTRS)

Kim, Edward

2015-01-01

Discussions within the international snow remote sensing community over the past two years have led to encouraging consensus regarding the broad outlines of a dedicated snow observing mission. The primary consensus - that since no single sensor type is satisfactory across all snow types and across all confounding factors, a multi-sensor approach is required - naturally leads to questions about the exact mix of sensors, required accuracies, and so on. In short, the natural next step is to collect such multi-sensor snow observations (with detailed ground truth) to enable trade studies of various possible mission concepts. Such trade studies must assess the strengths and limitations of heritage as well as newer measurement techniques with an eye toward natural sensitivity to desired parameters such as snow depth and/or snow water equivalent (SWE) in spite of confounding factors like clouds, lack of solar illumination, forest cover, and topography, measurement accuracy, temporal and spatial coverage, technological maturity, and cost.

The effect of spaceflight and microgravity on the human brain.

PubMed

Van Ombergen, Angelique; Demertzi, Athena; Tomilovskaya, Elena; Jeurissen, Ben; Sijbers, Jan; Kozlovskaya, Inessa B; Parizel, Paul M; Van de Heyning, Paul H; Sunaert, Stefan; Laureys, Steven; Wuyts, Floris L

2017-10-01

Microgravity, confinement, isolation, and immobilization are just some of the features astronauts have to cope with during space missions. Consequently, long-duration space travel can have detrimental effects on human physiology. Although research has focused on the cardiovascular and musculoskeletal system in particular, the exact impact of spaceflight on the human central nervous system remains to be determined. Previous studies have reported psychological problems, cephalic fluid shifts, neurovestibular problems, and cognitive alterations, but there is paucity in the knowledge of the underlying neural substrates. Previous space analogue studies and preliminary spaceflight studies have shown an involvement of the cerebellum, cortical sensorimotor, and somatosensory areas and the vestibular pathways. Extending this knowledge is crucial, especially in view of long-duration interplanetary missions (e.g., Mars missions) and space tourism. In addition, the acquired insight could be relevant for vestibular patients, patients with neurodegenerative disorders, as well as the elderly population, coping with multisensory deficit syndromes, immobilization, and inactivity.

Mapping coastal sea level at high resolution with radar interferometry: the SWOT Mission

NASA Astrophysics Data System (ADS)

Fu, L. L.; Chao, Y.; Laignel, B.; Turki, I., Sr.

2017-12-01

The spatial resolution of the present constellation of radar altimeters in mapping two-dimensional sea surface height (SSH) variability is approaching 100 km (in wavelength). At scales shorter than 100 km, the eddies and fronts are responsible for the stirring and mixing of the ocean, especially important in the various coastal processes. A mission currently in development will make high-resolution measurement of the height of water over the ocean as well as on land. It is called Surface Water and Ocean Topography (SWOT), which is a joint mission of US NASA and French CNES, with contributions from Canada and UK. SWOT will carry a pair of interferometry radars and make 2-dimensional SSH measurements over a swath of 120 km with a nadir gap of 20 km in a 21-day repeat orbit. The synthetic aperture radar of SWOT will make SSH measurement at extremely high resolution of 10-70 m. SWOT will also carry a nadir looking conventional altimeter and make 1-dimensional SSH measurements along the nadir gap. The temporal sampling varies from 2 repeats per 21 days at the equator to more than 4 repeats at mid latitudes and more than 6 at high latitudes. This new mission will allow a continuum of fine-scale observations from the open ocean to the coasts, estuaries and rivers, allowing us to investigate a number of scientific and technical questions in the coastal and estuarine domain to assess the coastal impacts of regional sea level change, such as the interaction of sea level with river flow, estuary inundation, storm surge, coastal wetlands, salt water intrusion, etc. As examples, we will illustrate the potential impact of SWOT to the studies of the San Francisco Bay Delta, and the Seine River estuary, etc. Preliminary results suggest that the SWOT Mission will provide fundamental data to map the spatial variability of water surface elevations under different hydrodynamic conditions and at different scales (local, regional and global) to improve our knowledge of the complex physical processes in the coastal and estuarine systems in response to global sea level changes.

Development of Generic Aircrew Measures of Performance for Distributed Mission Training

DTIC Science & Technology

2003-03-31

collecte de données utiles sur les performances humaines représente des défis considérables. De plus, on ne trouvera pas deux essais d’IMD exactement...weapons Countered bandits offensive Very sound energy management and aircraft manoeuvering Quickly capitalized on offensive position...Effectively countered bandits offensive to a neutral position Ideal Aircraft energy management and manoeuvering Expeditiously capitalized on

A Numerical and Theoretical Study of Seismic Wave Diffraction in Complex Geologic Structure

DTIC Science & Technology

1989-04-14

element methods for analyzing linear and nonlinear seismic effects in the surficial geologies relevant to several Air Force missions. The second...exact solution evaluated here indicates that edge-diffracted seismic wave fields calculated by discrete numerical methods probably exhibits significant...study is to demonstrate and validate some discrete numerical methods essential for analyzing linear and nonlinear seismic effects in the surficial

Japan Report.

DTIC Science & Technology

1987-02-03

of Keidanren’s U.S. Investment Mission, who is also vice chairman of the Industrial Bank of Japan; Mamoru Sakai, leader of the B Group of...Keidanren’s U.S. Investment Mission, who is also a director of the Japan Long-Term Credit Bank ; Masayoshi Tozaki, leader of the C Group of Keidanren’s U.S...Constitution. At the same time, Federal Reserve Bank Chairman Volcker has repeatedly stressed that maintaining the value of the dollar is essential. In

Space Radiation Induced Cytogenetic Damage in the Blood Lymphocytes of Astronauts: Persistence of Damage After Flight and the Effects of Repeat Long Duration Missions

NASA Technical Reports Server (NTRS)

George, Kerry; Rhone, Jordan; Chappell, L. J.; Cucinotta, F. A.

2010-01-01

Cytogenetic damage was assessed in blood lymphocytes from astronauts before and after they participated in long-duration space missions of three months or more. The frequency of chromosome damage was measured by fluorescence in situ hybridization (FISH) chromosome painting before flight and at various intervals from a few days to many months after return from the mission. For all individuals, the frequency of chromosome exchanges measured within a month of return from space was higher than their prefight yield. However, some individuals showed a temporal decline in chromosome damage with time after flight. Statistical analysis using combined data for all astronauts indicated a significant overall decreasing trend in total chromosome exchanges with time after flight, although this trend was not seen for all astronauts and the yield of chromosome damage in some individuals actually increased with time after flight. The decreasing trend in total exchanges was slightly more significant when statistical analysis was restricted to data collected more than 220 days after return from flight. In addition, limited data on multiple flights show a lack of correlation between time in space and translocation yields. Data from three crewmembers who has participated in two separate long-duration space missions provide limited information on the effect of repeat flights and show a possible adaptive response to space radiation exposure.

Scientific data reduction and analysis plan: PI services

NASA Technical Reports Server (NTRS)

Feldman, P. D.; Fastie, W. G.

1971-01-01

This plan comprises two parts. The first concerns the real-time data display to be provided by MSC during the mission. The prime goal is to assess the operation of the UVS and to identify any problem areas that could be corrected during the mission. It is desirable to identify any possible observations of unusual scientific interest in order to repeat these observations at a later point in the mission, or to modify the time line with respect to the operating modes of the UVS. The second part of the plan discusses the more extensive postflight analysis of the data in terms of the scientific objectives of this experiment.

Repeated significance tests of linear combinations of sensitivity and specificity of a diagnostic biomarker

PubMed Central

Wu, Mixia; Shu, Yu; Li, Zhaohai; Liu, Aiyi

2016-01-01

A sequential design is proposed to test whether the accuracy of a binary diagnostic biomarker meets the minimal level of acceptance. The accuracy of a binary diagnostic biomarker is a linear combination of the marker’s sensitivity and specificity. The objective of the sequential method is to minimize the maximum expected sample size under the null hypothesis that the marker’s accuracy is below the minimal level of acceptance. The exact results of two-stage designs based on Youden’s index and efficiency indicate that the maximum expected sample sizes are smaller than the sample sizes of the fixed designs. Exact methods are also developed for estimation, confidence interval and p-value concerning the proposed accuracy index upon termination of the sequential testing. PMID:26947768

Precision Attitude Determination for an Infrared Space Telescope

NASA Technical Reports Server (NTRS)

Benford, Dominic J.

2008-01-01

We have developed performance simulations for a precision attitude determination system using a focal plane star tracker on an infrared space telescope. The telescope is being designed for the Destiny mission to measure cosmologically distant supernovae as one of the candidate implementations for the Joint Dark Energy Mission. Repeat observations of the supernovae require attitude control at the level of 0.010 arcseconds (0.05 microradians) during integrations and at repeat intervals up to and over a year. While absolute accuracy is not required, the repoint precision is challenging. We have simulated the performance of a focal plane star tracker in a multidimensional parameter space, including pixel size, read noise, and readout rate. Systematic errors such as proper motion, velocity aberration, and parallax can be measured and compensated out. Our prediction is that a relative attitude determination accuracy of 0.001 to 0.002 arcseconds (0.005 to 0.010 microradians) will be achievable.

Reprocessing the GRACE-derived gravity field time series based on data-driven method for ocean tide alias error mitigation

NASA Astrophysics Data System (ADS)

Liu, Wei; Sneeuw, Nico; Jiang, Weiping

2017-04-01

GRACE mission has contributed greatly to the temporal gravity field monitoring in the past few years. However, ocean tides cause notable alias errors for single-pair spaceborne gravimetry missions like GRACE in two ways. First, undersampling from satellite orbit induces the aliasing of high-frequency tidal signals into the gravity signal. Second, ocean tide models used for de-aliasing in the gravity field retrieval carry errors, which will directly alias into the recovered gravity field. GRACE satellites are in non-repeat orbit, disabling the alias error spectral estimation based on the repeat period. Moreover, the gravity field recovery is conducted in non-strictly monthly interval and has occasional gaps, which result in an unevenly sampled time series. In view of the two aspects above, we investigate the data-driven method to mitigate the ocean tide alias error in a post-processing mode.

Phased-mission system analysis using Boolean algebraic methods

NASA Technical Reports Server (NTRS)

Somani, Arun K.; Trivedi, Kishor S.

1993-01-01

Most reliability analysis techniques and tools assume that a system is used for a mission consisting of a single phase. However, multiple phases are natural in many missions. The failure rates of components, system configuration, and success criteria may vary from phase to phase. In addition, the duration of a phase may be deterministic or random. Recently, several researchers have addressed the problem of reliability analysis of such systems using a variety of methods. A new technique for phased-mission system reliability analysis based on Boolean algebraic methods is described. Our technique is computationally efficient and is applicable to a large class of systems for which the failure criterion in each phase can be expressed as a fault tree (or an equivalent representation). Our technique avoids state space explosion that commonly plague Markov chain-based analysis. A phase algebra to account for the effects of variable configurations and success criteria from phase to phase was developed. Our technique yields exact (as opposed to approximate) results. The use of our technique was demonstrated by means of an example and present numerical results to show the effects of mission phases on the system reliability.

Design and Requirements Creep In A Build-To-Print Mission

NASA Technical Reports Server (NTRS)

Peabody, Sharon A.; Otero, Veronica

2017-01-01

Build-to-Print designs, or rebuilds of flight proven designs, are attractive to mission stakeholders, as they give the appearance of minimal engineering development cost, risk, and schedule. The reality is that seldom is a project an exact duplicate of a predecessor. Mission reclassification, improvements in hardware, and science objective changes can all serve as a source of requirements and design creep and have ramifications often not fully anticipated during initial proposals. The Thermal Infrared Sensor Instrument (TIRS) was a late addition to the LandSat-8 program to provide infrared imaging to measure evapotranspiration for water cycle management. To meet the launch requirements for LandSat-8, instrument design life requirements were relaxed, the sensor development expedited, and technology development was minimized. Consequently, TIRS was designed as a higher risk instrument, with less redundancy than an instrument critical to mission success. After the successful LandSat-8 launch in 2013 and instrument performance, a rebuild of the instrument for the next LandSat spacecraft was included in the baseline mission success criteria. This paper discusses the technical challenges encountered during the rebuild of the TIRS-2 (Thermal Infrared Sensor 2) instrument and the resultant impacts on the thermal system design.

STS-86 Crew Lunch in O&C Building

NASA Technical Reports Server (NTRS)

1997-01-01

As part of the final STS-86 prelaunch activities, the seven crew members gather for a snack and a photo opportunity in the Operations and Checkout Building. From left, are Mission Specialist Wendy B. Lawrence, Pilot Michael J. Bloomfield, Mission Specialist Scott E. Parazynski, Commander James D. Wetherbee, Mission Specialist David A. Wolf, Mission Specialist Jean-Loup J.M. Chretien of the French Space Agency, CNES, and Mission Specialist Vladimir Georgievich Titov of the Russian Space Agency. After a weather briefing, the astronauts will don their orange launch and entry suits and depart for Launch Pad 39A, where the Space Shuttle Atlantis awaits liftoff at about 10:34 p.m. EDT, Sept. 25. The exact launch time may vary slightly based on calculations of the Russian Space Station Mirs precise location in space at the time of liftoff. STS-86 is slated to be the seventh of nine planned dockings of the Shuttle with the Mir. Wolf is scheduled to become a member of the Mir 24 crew, replacing U.S. astronaut C. Michael Foale, who will return to Earth aboard Atlantis after more than four months on the Russian orbiting outpost.

The Distribution of Ice in Lunar Permanently Shadowed Regions: Science Enabling Exploration (Invited)

NASA Astrophysics Data System (ADS)

Hurley, D.; Elphic, R. C.; Bussey, B.; Hibbitts, C.; Lawrence, D. J.

2013-12-01

Recent prospecting indicates that water ice occurs in enhanced abundances in some lunar PSRs. That water constitutes a resource that enables lunar exploration if it can be harvested for fuel and life support. Future lunar exploration missions will need detailed information about the distribution of volatiles in lunar permanently shadowed regions (PSRs). In addition, the volatiles also offer key insights into the recent and distant past, as they have trapped volatiles delivered to the moon over ~2 Gyr. This comprises an unparalleled reservoir of past inner solar system volatiles, and future scientific missions are needed to make the measurements that will reveal the composition of those volatiles. These scientific missions will necessarily have to acquire and analyze samples of volatiles from the PSRs. For both exploration and scientific purposes, the precise location of volatiles will need to be known. However, data indicate that ice is distributed heterogeneously on the Moon. It is unlikely that the distribution will be known a priori with enough spatial resolution to guarantee access to volatiles using a single point sample. Some mechanism for laterally or vertically distributed access will increase the likelihood of acquiring a rich sample of volatiles. Trade studies will need to be conducted to anticipate the necessary range and duration of missions to lunar PSRs that will be needed to accomplish the mission objectives. We examine the spatial distribution of volatiles in lunar PSRs reported from data analyses and couple those with models of smaller scale processes. FUV and laser data from PSRs that indicate the average surface distribution is consistent with low abundances on the extreme surface in most PSRs. Neutron and radar data that probe the distribution at depth show heterogeneity at broad spatial resolution. We consider those data in conjunction with the model to understand the full, 3-D nature of the heterogeneity. A Monte Carlo technique simulates the stochastic process of impact gardening on a putative ice deposit. The model uses the crater production function as a basis for generating a random selection of impact craters over time. Impacts are implemented by modifying the topography, volatile content, and depth distribution in the simulation volume on a case by case basis. This technique will never be able to reproduce the exact impact history of a particular area. But by conducting multiple runs with the same initial conditions and a different seed to the random number generator, we are able to calculate the probability of situations occurring. Further, by repeating the simulations with varied initial conditions, we calculate the dependence of the expectation values on the inputs. We present findings regarding the heterogeneity of volatiles in PSRs as a function of age, initial ice thickness, and contributions from steady sources.

Analysis of genetic relationships between potato psyllid (Bactericera cockerelli) populations in the United States, Mexico and Guatemala using ITS2 and inter simple sequence repeat (ISSR) data

USDA-ARS?s Scientific Manuscript database

The potato psyllid, Bactericera cockerelli (Sulc), is an important factor in Zebra Complex (ZC), a disease that causes economic losses on potato crops. Although the exact cause of ZC is not yet known, it may be related to the toxicity of psyllid saliva, pathogens transmitted by this insect, or a com...

Psychological characteristics of Swedish mandatory enlisted soldiers volunteering and not volunteering for international missions: an exploratory study.

PubMed

Rydstedt, Leif W; Osterberg, Johan

2013-04-01

The purpose of this study was to assess personality traits, psychological fitness, and hardiness among conscript soldiers volunteering for international missions (n = 146), by comparing them with conscripts from the same year class and unit who did not apply for international missions (n = 275). The sample consisted of all mandatory enlisted soldiers assigned to a supply and maintenance regiment. There were no demographic differences between the groups. The volunteers reported greater stress tolerance, concern for others, extraversion, and self-confidence than the non-volunteers. There were no differences between the groups in orderliness, temper instability, or independence. Volunteers repeatedly reported greater psychological fitness for military missions and greater hardiness over the period of military service compared to the non-volunteers.

New Radar Altimeter Missions are Providing a Dramatically Sharper Image of Global Marine Tectonics

NASA Astrophysics Data System (ADS)

Sandwell, D. T.; Müller, D.; Garcia, E.; Matthews, K. J.; Smith, W. H. F.; Zaron, E.; Zhang, S.; Bassett, D.; Francis, R.

2015-12-01

Marine gravity, derived from satellite radar altimetry, is a powerful tool for mapping tectonic structures, especially in the deep ocean basins where the topography remains unmapped by ships or is buried by thick sediment. The ability to infer seafloor tectonics from space was first demonstrated in 1978 using Seasat altimeter data but the spatial coverage was incomplete because of the short three-month lifetime of the satellite. Most ocean altimeters have repeat ground tracks with spacings of hundreds of kilometers so they do not resolve tectonic structures. Adequate altimeter coverage became available in 1995 when the United States Navy declassified the Geosat radar altimeter data and the ERS-1 altimeter completed a 1-year mapping phase. These mid-1990's altimeter-derived images of the ocean basins remained static for 15 years because there were no new non-repeat altimeter missions. This situation changed dramatically in 2010 when CryoSat-2, with its advanced radar altimeter, was launched into a non-repeat orbit and continues to collect data until perhaps 2020. In addition the Jason-1 altimeter was placed into a 14-month geodetic phase at the end of its lifetime. More recently the 1.5 times higher precision measurements from the AltiKa altimeter aboard the SARAL spacecraft began to drift away from its 35-day repeat trackline. The Chinese HY-2 altimeter is scheduled to begin a dense mapping phase in early 2016. Moreover in 2020 we may enjoy significantly higher resolution maps of the ocean basins from the planned SWOT altimeter mission with its advanced swath mapping ability. All of this new data will provide a much sharper image of the tectonics of the deep ocean basins and continental margins. During this talk we will tour of the new tectonic structures revealed by CryoSat-2 and Jason-1 and speculate on the tectonic views of the ocean basins in 2020 and beyond.

UAVSAR: Airborne L-band Radar for Repeat Pass Interferometry

NASA Technical Reports Server (NTRS)

Moes, Timothy R.

2009-01-01

The primary objectives of the UAVSAR Project were to: a) develop a miniaturized polarimetric L-band synthetic aperture radar (SAR) for use on an unmanned aerial vehicle (UAV) or piloted vehicle. b) develop the associated processing algorithms for repeat-pass differential interferometric measurements using a single antenna. c) conduct measurements of geophysical interest, particularly changes of rapidly deforming surfaces such as volcanoes or earthquakes. Two complete systems were developed. Operational Science Missions began on February 18, 2009 ... concurrent development and testing of the radar system continues.

Validated multiclass targeted determination of antibiotics in fish with high performance liquid chromatography-benchtop quadrupole orbitrap hybrid mass spectrometry.

PubMed

Chiesa, Luca; Panseri, Sara; Pasquale, Elisa; Malandra, Renato; Pavlovic, Radmila; Arioli, Francesco

2018-08-30

High performance liquid chromatography, coupled with a benchtop Q-Exactive Orbitrap high-resolution mass spectrometer, was successfully applied for the determination of 24 target antibiotics (selected beta-lactams, tetracyclines, fluoroquinolones, sulfonamids, phenicols, macrolides, cephalosporins, lincosamides, diaminopyrimidine) in fish matrices. The Q-Exactive parameters were carefully studied to accomplish the best compromise between a suitable scan speed and selectivity, considering the restrictions associated with generic sample preparation methodology. Retention time, an exact mass with tolerance of 2 ppm and data-dependent MS 2 spectra were the main identifiers. The method was validated through specificity, linearity, recovery, intra- and inter-day repeatability, decision limit (CCα) and detection capability (CCβ), according to 2002/657/EC. The values of CCα and CCβ ranged from 29.2 to 36.8 and 32.5 to 48.9, respectively, while overall recovery ranged from 91.1 to 105.6%. Fifty fish samples were analysed, showing the sporadic incidence of enrofloxacin, chlortetracycline, oxytetracycline, amoxicillin and trimethoprim, albeit below the maximum residual levels. Copyright © 2018 Elsevier Ltd. All rights reserved.

OGO program summary, supplement 1. [updated bibliography for all OGO missions and scientific results from OGO 5 and 6 missions

NASA Technical Reports Server (NTRS)

Jackson, J. E.

1978-01-01

Scientific results from OGO-5 and OGO-6 experiments are summarized and approximately 200 citations are included to update the 1975 OGO bibliography. Personal author, subject, and corporate source indexes are included. The supplement follows the same format as that of the OGO Program Summary; it does not repeat the finalized information in the original publication, which should be consulted for indexes of experiments, experimenters, institutions, and the glossary of abbreviations and acronyms.

Unification Strategy for North and South Korea: The Most Prudent U.S. Policy Option to Solve the North Korean Nuclear Crisis

DTIC Science & Technology

2004-09-01

the 1882 expedition, hoping to not repeat the mistakes of the Low mission, was much more conciliatory toward King Kojong. The result was the U.S...diplomatic in its approach. In a letter to King Kojong before his mission, Shufeldt expressed his wish to bring about an “amicable intercourse” between...regard, Korea and Vietnam were China’s most reliable traditional allies. In exchange, China promised to defend the domains of neighboring kings who

NASA's Soil Moisture Active and Passive (SMAP) Mission

NASA Technical Reports Server (NTRS)

Kellogg, Kent; Njoku, Eni; Thurman, Sam; Edelstein, Wendy; Jai, Ben; Spencer, Mike; Chen, Gun-Shing; Entekhabi, Dara; O'Neill, Peggy; Piepmeier, Jeffrey;

Ensemble: an Architecture for Mission-Operations Software

NASA Technical Reports Server (NTRS)

Norris, Jeffrey; Powell, Mark; Fox, Jason; Rabe, Kenneth; Shu, IHsiang; McCurdy, Michael; Vera, Alonso

2008-01-01

Ensemble is the name of an open architecture for, and a methodology for the development of, spacecraft mission operations software. Ensemble is also potentially applicable to the development of non-spacecraft mission-operations- type software. Ensemble capitalizes on the strengths of the open-source Eclipse software and its architecture to address several issues that have arisen repeatedly in the development of mission-operations software: Heretofore, mission-operations application programs have been developed in disparate programming environments and integrated during the final stages of development of missions. The programs have been poorly integrated, and it has been costly to develop, test, and deploy them. Users of each program have been forced to interact with several different graphical user interfaces (GUIs). Also, the strategy typically used in integrating the programs has yielded serial chains of operational software tools of such a nature that during use of a given tool, it has not been possible to gain access to the capabilities afforded by other tools. In contrast, the Ensemble approach offers a low-risk path towards tighter integration of mission-operations software tools.

Global-scale Observations of the Limb and Disk (GOLD) Mission -Ultraviolet Remote Sensing of Earth's Space Environment from Geostationary Orbit

NASA Astrophysics Data System (ADS)

Burns, A. G.; Eastes, R.

2017-12-01

The GOLD mission of opportunity will fly a far ultraviolet imaging spectrograph in geostationary (GEO) orbit as a hosted payload. The mission is scheduled for launch in late January 2018 on SES-14, a commercial communications satellite that will be stationed over eastern South America at 47.5 degrees west longitude. GOLD is on schedule to be the first NASA science mission to fly as a hosted payload on a commercial communications satellite. The GOLD imager has two identical channels. Each channel can scan the full disk at a 30 minute cadence, making spectral images of Earth's UV emission from 132 to 162 nm, as well as make a measurement on the Earth's limb. Remote sensing techniques that have been proven on previous Low Earth Orbit (LEO) missions will be used to derive fundamental parameters for the neutral and ionized space environment. Parameters that will be derived include composition (O/N2 ratio) and temperature of the neutral atmosphere on the dayside disk. On the nightside, peak electron densities will be obtained in the low latitude ionosphere. Many of the algorithms developed for the mission are extensions of ones used on previous earth and planetary missions, with modifications for observations from geostationary orbit. All the algorithms have been tested using simulated observations based on the actual instrument performance. From geostationary orbit, GOLD can repeatedly image the same geographic locations over most of the hemisphere at a cadence comparable to that of the T-I system (order of an hour). Such time resolution and spatial coverage will allow the mission to track the changes due to geomagnetic storms, variations in solar extreme ultraviolet radiation, and forcing from the lower atmosphere. In addition to providing a new perspective by being able to repeatedly remotely sense the same hemisphere at a high cadence, GOLD's simultaneous measurements of not only composition but also temperatures across the disk will provide a valuable, new parameter for understanding of how the T-I system responds to forcing from both the sun and the lower atmosphere.

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

PubMed Central

Schawalder, James; Paric, Enesa; Neff, Norma F

2003-01-01

Background Bloom syndrome is one of the most cancer-predisposing disorders and is characterized by genomic instability and a high frequency of sister chromatid exchange. The disorder is caused by loss of function of a 3' to 5' RecQ DNA helicase, BLM. The exact role of BLM in maintaining genomic integrity is not known but the helicase has been found to associate with several DNA repair complexes and some DNA replication foci. Results Chromatin immunoprecipitation of BLM complexes recovered telomere and ribosomal DNA repeats. The N-terminus of BLM, required for NB localization, is the same as the telomere association domain of BLM. The C-terminus is required for ribosomal DNA localization. BLM localizes primarily to the non-transcribed spacer region of the ribosomal DNA repeat where replication forks initiate. Bloom syndrome cells expressing the deletion alleles lacking the ribosomal DNA and telomere association domains have altered cell cycle populations with increased S or G2/M cells relative to normal. Conclusion These results identify telomere and ribosomal DNA repeated sequence elements as chromosomal targets for the BLM DNA helicase during the S/G2 phase of the cell cycle. BLM is localized in nuclear bodies when it associates with telomeric repeats in both telomerase positive and negative cells. The BLM DNA helicase participates in genomic stability at ribosomal DNA repeats and telomeres. PMID:14577841

US Search and Rescue Mission Control Center functions

NASA Technical Reports Server (NTRS)

1977-01-01

A satellite aided Search and Rescue (SAR) Mission concept consisting of a local coverage bent pipe system, and a global coverage system is described. The SAR instrument is to consist of a Canadian repeater and a French processor for which Canada and France, respectively are to evaluate health and trends. Performance evaluations of each system were provided. The United States and Canada will each have a Search and Rescue Mission Control Center (MCC) and their functions were also examined. A summary of the interface requirements necessary to perform each function was included as well as the information requirements between the USMCC and each of its interfaces. Physical requirements such as location, manning etc. of the USMCC were discussed.

Mars Climate Orbiter

NASA Technical Reports Server (NTRS)

1998-01-01

The purpose of this mission is to study the climate history and the water distribution of Mars. Beautiful panoramic views of the shuttle on the launch pad, engine ignition, Rocket launch, and the separation and burnout of the Solid Rocket Boosters are shown. The footage also includes an animation of the mission. Detailed views of the path that the Orbiter traversed were shown. Once the Orbiter lands on the surface of Mars, it will dig a six to eight inch hole and collect samples from the planets' surface. The animation also included the prospective return of the Orbiter to Earth over the desert of Utah. The remote sensor on the Orbiter helps in finding the exact location of the Orbiter so that scientists may collect the sample and analyze it.

Infrared instrument support for HyspIRI-TIR

NASA Astrophysics Data System (ADS)

Johnson, William R.; Hook, Simon J.; Foote, Marc; Eng, Bjorn T.; Jau, Bruno

2012-10-01

The Jet Propulsion Laboratory is currently developing an end-to-end instrument which will provide a proof of concept prototype vehicle for a high data rate, multi-channel, thermal instrument in support of the Hyperspectral Infrared Imager (HyspIRI)-Thermal Infrared (TIR) space mission. HyspIRI mission was recommended by the National Research Council Decadal Survey (DS). The HyspIRI mission includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. The prototype testbed instrument addressed in this effort will only support the TIR. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. Current designs for the HyspIRI-TIR space borne imager utilize eight spectral bands delineated with filters. The system will have 60m ground resolution, 200mK NEDT, 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. The prototype instrument will use mercury cadmium telluride (MCT) technology at the focal plane array in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence high data rates needed for the 5 day repeat. The current HyspIRI requirements dictate a ground knowledge measurement of 30m, so the prototype instrument will tackle this problem with a newly developed interferometeric metrology system. This will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing post-processing (e.g. geo-rectification computations).

High speed, multi-channel, thermal instrument development in support of HyspIRI-TIR

NASA Astrophysics Data System (ADS)

Johnson, William R.; Hook, Simon J.; Foote, Marc; Eng, Bjorn T.; Jau, Bruno

2011-10-01

The Jet Propulsion Laboratory is currently developing an end-to-end instrument which will provide a proof of concept prototype vehicle for a high data rate, multi-channel, thermal instrument in support of the Hyperspectral Infrared Imager (HyspIRI)-Thermal Infrared (TIR) space mission. HyspIRI mission was recommended by the National Research Council Decadal Survey (DS). The HyspIRI mission includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. The prototype testbed instrument addressed in this effort will only support the TIR. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. Current designs for the HyspIRI-TIR space borne imager utilize eight spectral bands delineated with filters. The system will have 60m ground resolution, 200mK NEDT, 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. The prototype instrument will use mercury cadmium telluride (MCT) technology at the focal plane array in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence high data rates needed for the 5 day repeat. The current HyspIRI requirements dictate a ground knowledge measurement of 30m, so the prototype instrument will tackle this problem with a newly developed interferometeric metrology system. This will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing postprocessing (e.g. geo-rectification computations).

A fast exact simulation method for a class of Markov jump processes.

PubMed

Li, Yao; Hu, Lili

2015-11-14

A new method of the stochastic simulation algorithm (SSA), named the Hashing-Leaping method (HLM), for exact simulations of a class of Markov jump processes, is presented in this paper. The HLM has a conditional constant computational cost per event, which is independent of the number of exponential clocks in the Markov process. The main idea of the HLM is to repeatedly implement a hash-table-like bucket sort algorithm for all times of occurrence covered by a time step with length τ. This paper serves as an introduction to this new SSA method. We introduce the method, demonstrate its implementation, analyze its properties, and compare its performance with three other commonly used SSA methods in four examples. Our performance tests and CPU operation statistics show certain advantages of the HLM for large scale problems.

From NGS assembly challenges to instability of fungal mitochondrial genomes: A case study in genome complexity.

PubMed

Misas, Elizabeth; Muñoz, José Fernando; Gallo, Juan Esteban; McEwen, Juan Guillermo; Clay, Oliver Keatinge

2016-04-01

The presence of repetitive or non-unique DNA persisting over sizable regions of a eukaryotic genome can hinder the genome's successful de novo assembly from short reads: ambiguities in assigning genome locations to the non-unique subsequences can result in premature termination of contigs and thus overfragmented assemblies. Fungal mitochondrial (mtDNA) genomes are compact (typically less than 100 kb), yet often contain short non-unique sequences that can be shown to impede their successful de novo assembly in silico. Such repeats can also confuse processes in the cell in vivo. A well-studied example is ectopic (out-of-register, illegitimate) recombination associated with repeat pairs, which can lead to deletion of functionally important genes that are located between the repeats. Repeats that remain conserved over micro- or macroevolutionary timescales despite such risks may indicate functionally or structurally (e.g., for replication) important regions. This principle could form the basis of a mining strategy for accelerating discovery of function in genome sequences. We present here our screening of a sample of 11 fully sequenced fungal mitochondrial genomes by observing where exact k-mer repeats occurred several times; initial analyses motivated us to focus on 17-mers occurring more than three times. Based on the diverse repeats we observe, we propose that such screening may serve as an efficient expedient for gaining a rapid but representative first insight into the repeat landscapes of sparsely characterized mitochondrial chromosomes. Our matching of the flagged repeats to previously reported regions of interest supports the idea that systems of persisting, non-trivial repeats in genomes can often highlight features meriting further attention. Copyright © 2016 Elsevier Ltd. All rights reserved.

On Nash Equilibrium and Evolutionarily Stable States That Are Not Characterised by the Folk Theorem

PubMed Central

Li, Jiawei; Kendall, Graham

2015-01-01

In evolutionary game theory, evolutionarily stable states are characterised by the folk theorem because exact solutions to the replicator equation are difficult to obtain. It is generally assumed that the folk theorem, which is the fundamental theory for non-cooperative games, defines all Nash equilibria in infinitely repeated games. Here, we prove that Nash equilibria that are not characterised by the folk theorem do exist. By adopting specific reactive strategies, a group of players can be better off by coordinating their actions in repeated games. We call it a type-k equilibrium when a group of k players coordinate their actions and they have no incentive to deviate from their strategies simultaneously. The existence and stability of the type-k equilibrium in general games is discussed. This study shows that the sets of Nash equilibria and evolutionarily stable states have greater cardinality than classic game theory has predicted in many repeated games. PMID:26288088

Intelligence is in the eye of the beholder: investigating repeated IQ measurements in forensic psychiatry.

PubMed

Habets, Petra; Jeandarme, Inge; Uzieblo, Kasia; Oei, Karel; Bogaerts, Stefan

2015-05-01

A stable assessment of cognition is of paramount importance for forensic psychiatric patients (FPP). The purpose of this study was to compare repeated measures of IQ scores in FPPs with and without intellectual disability. Repeated measurements of IQ scores in FPPs (n = 176) were collected. Differences between tests were computed, and each IQ score was categorized. Additionally, t-tests and regression analyses were performed. Differences of 10 points or more were found in 66% of the cases comparing WAIS-III with RAVEN scores. Fisher's exact test revealed differences between two WAIS-III scores and the WAIS categories. The WAIS-III did not predict other IQs (WAIS or RAVEN) in participants with intellectual disability. This study showed that stability or interchangeability of scores is lacking, especially in individuals with intellectual disability. Caution in interpreting IQ scores is therefore recommended, and the use of the unitary concept of IQ should be discouraged. © 2014 John Wiley & Sons Ltd.

Monte Carlo Simulations Comparing Fisher Exact Test and Unequal Variances t Test for Analysis of Differences Between Groups in Brief Hospital Lengths of Stay.

PubMed

Dexter, Franklin; Bayman, Emine O; Dexter, Elisabeth U

2017-12-01

We examined type I and II error rates for analysis of (1) mean hospital length of stay (LOS) versus (2) percentage of hospital LOS that are overnight. These 2 end points are suitable for when LOS is treated as a secondary economic end point. We repeatedly resampled LOS for 5052 discharges of thoracoscopic wedge resections and lung lobectomy at 26 hospitals. Unequal variances t test (Welch method) and Fisher exact test both were conservative (ie, type I error rate less than nominal level). The Wilcoxon rank sum test was included as a comparator; the type I error rates did not differ from the nominal level of 0.05 or 0.01. Fisher exact test was more powerful than the unequal variances t test at detecting differences among hospitals; estimated odds ratio for obtaining P < .05 with Fisher exact test versus unequal variances t test = 1.94, with 95% confidence interval, 1.31-3.01. Fisher exact test and Wilcoxon-Mann-Whitney had comparable statistical power in terms of differentiating LOS between hospitals. For studies with LOS to be used as a secondary end point of economic interest, there is currently considerable interest in the planned analysis being for the percentage of patients suitable for ambulatory surgery (ie, hospital LOS equals 0 or 1 midnight). Our results show that there need not be a loss of statistical power when groups are compared using this binary end point, as compared with either Welch method or Wilcoxon rank sum test.

Relative Positioning Evaluation of a Tetrahedral Flight Formation’s Satellites

NASA Astrophysics Data System (ADS)

Mahler, W. F. C.; Rocco, E. M.; Santos, D. P. S.

2017-10-01

This paper presents a study about the tetrahedral layout of four satellites in a way that every half-orbital period this set groups together while flying in formation. The formation is calculated analyzing the problem from a geometrical perspective and disposed by precisely adjusting the orbital parameters of each satellite. The dynamic modelling considers the orbital motion equations. The results are analyzed, compared and discussed. A detection algorithm is used as flag to signal the regular tetrahedron’s exact moments of occurrence. To do so, the volume calculated during the simulation is compared to the real volume, based on the initial conditions of the exact moment of formation and respecting a tolerance. This tolerance value is stablished arbitrarily depending on the mission and the formation’s geometrical parameters. The simulations will run on a computational environment.

Global-scale Observations of the Limb and Disk (GOLD) Mission - Observing Forcing of the Thermosphere-Ionosphere System from Above and Below

NASA Astrophysics Data System (ADS)

Eastes, Richard; McClintock, William; Burns, Alan

2015-04-01

The GOLD mission will provide unprecedented imaging of the Earth’s space environment and its response to forcing from the Sun and the lower atmosphere. The mission will fly a far ultraviolet imaging spectrograph and is scheduled for launch into geostationary (GEO) orbit in October 2017 as a hosted payload on a commercial communications satellite flying over eastern South America. From this vantage point GOLD will repeatedly image the American hemisphere at a thirty-minute cadence. Fundamental parameters that will be derived from these measurements include composition (O/N2) and temperature of the neutral atmosphere on the dayside disk. Imaging of atmospheric composition, at only a daily cadence, has already provided many new insights into the behavior of the Thermosphere-Ionosphere (T-I) system. Combining composition with simultaneous temperature images will provide revolutionary insights into the behavior of the T-I system and its response to external forcing. Since GOLD will repeatedly observe the same geographic locations, it can distinguish between spatial and temporal variations in the TI system caused by geomagnetic storms, variations in solar EUV, and forcing from the lower atmosphere. GOLD’s measurements and observing approach will give the scientific community a new understanding of the T-I system.

Accurate approximation of in-ecliptic trajectories for E-sail with constant pitch angle

NASA Astrophysics Data System (ADS)

Huo, Mingying; Mengali, Giovanni; Quarta, Alessandro A.

2018-05-01

Propellantless continuous-thrust propulsion systems, such as electric solar wind sails, may be successfully used for new space missions, especially those requiring high-energy orbit transfers. When the mass-to-thrust ratio is sufficiently large, the spacecraft trajectory is characterized by long flight times with a number of revolutions around the Sun. The corresponding mission analysis, especially when addressed within an optimal context, requires a significant amount of simulation effort. Analytical trajectories are therefore useful aids in a preliminary phase of mission design, even though exact solution are very difficult to obtain. The aim of this paper is to present an accurate, analytical, approximation of the spacecraft trajectory generated by an electric solar wind sail with a constant pitch angle, using the latest mathematical model of the thrust vector. Assuming a heliocentric circular parking orbit and a two-dimensional scenario, the simulation results show that the proposed equations are able to accurately describe the actual spacecraft trajectory for a long time interval when the propulsive acceleration magnitude is sufficiently small.

Implementation and Test of the Automatic Flight Dynamics Operations for Geostationary Satellite Mission

NASA Astrophysics Data System (ADS)

Park, Sangwook; Lee, Young-Ran; Hwang, Yoola; Javier Santiago Noguero Galilea

2009-12-01

This paper describes the Flight Dynamics Automation (FDA) system for COMS Flight Dynamics System (FDS) and its test result in terms of the performance of the automation jobs. FDA controls the flight dynamics functions such as orbit determination, orbit prediction, event prediction, and fuel accounting. The designed FDA is independent from the specific characteristics which are defined by spacecraft manufacturer or specific satellite missions. Therefore, FDA could easily links its autonomous job control functions to any satellite mission control system with some interface modification. By adding autonomous system along with flight dynamics system, it decreases the operator’s tedious and repeated jobs but increase the usability and reliability of the system. Therefore, FDA is used to improve the completeness of whole mission control system’s quality. The FDA is applied to the real flight dynamics system of a geostationary satellite, COMS and the experimental test is performed. The experimental result shows the stability and reliability of the mission control operations through the automatic job control.

Targetting and guidance program documentation. [a user's manual

NASA Technical Reports Server (NTRS)

Harrold, E. F.; Neyhard, J. F.

1974-01-01

A FORTRAN computer program was developed which automatically targets two and three burn rendezvous missions and performs feedback guidance using the GUIDE algorithm. The program was designed to accept a large class of orbit specifications and to automatically choose a two or three burn mission depending upon the time alignment of the vehicle and target. The orbits may be specified as any combination of circular and elliptical orbits and may be coplanar or inclined, but must be aligned coaxially with their perigees in the same direction. The program accomplishes the required targeting by repeatedly converging successively more complex missions. It solves the coplanar impulsive version of the mission, then the finite burn coplanar mission, and finally, the full plane change mission. The GUIDE algorithm is exercised in a feedback guidance mode by taking the targeted solution and moving the vehicle state step by step ahead in time, adding acceleration and navigational errors, and reconverging from the perturbed states at fixed guidance update intervals. A program overview is presented, along with a user's guide which details input, output, and the various subroutines.

Monthly and Fortnightly Tidal Variations of the Earth's Rotation Rate Predicted by a TOPEX/POSEIDON Empirical Ocean Tide Model

NASA Technical Reports Server (NTRS)

Desai, S.; Wahr, J.

1998-01-01

Empirical models of the two largest constituents of the long-period ocean tides, the monthly and the fortnightly constituents, are estimated from repeat cycles 10 to 210 of the TOPEX/POSEIDON (T/P) mission.

Close-up multispectral images of the surface of comet 67P/Churyumov-Gerasimenko by the ROLIS camera onboard the Rosetta Philae lander

NASA Astrophysics Data System (ADS)

Schroeder, S.; Mottola, S.; Arnold, G.; Grothues, H. G.; Jaumann, R.; Michaelis, H.; Neukum, G.; Pelivan, I.; Bibring, J. P.

2014-12-01

In November 2014 the Philae lander onboard Rosetta is scheduled to land on the surface of comet 67P/Churyumov-Gerasimenko. The ROLIS camera will provide the ground truth for the Rosetta OSIRIS camera. ROLIS will acquire images both during the descent and after landing. In this paper we concentrate on the post-landing images. The close-up images will enable us to characterize the morphology and texture of the surface, and the shape, albedo, and size distribution of the particles on scales as small as 0.3 mm per pixel. We may see evidence for a dust mantle, a refractory crust, and exposed ice. In addition, we hope to identify features such as pores, cracks, or vents that allow volatiles to escape the surface. We will not only image the surface during the day but also the night, when LEDs will illuminate the surface in four different colors (blue, green, red, near-IR). This will characterize the spectral properties and heterogeneity of the surface, helping us to identify its composition. Although the ROLIS spectral range and resolution are too limited to allow an exact mineralogical characterization, a study of the spectral slope and albedo will allow a broad classification of the solid surface phases. We expect to be able to distinguish between organic material, silicates and ices. By repeated imaging over the course of the mission ROLIS may detect long term changes associated with cometary activity.

A note on sea level variability at Clipperton Island from GEOSAT and in-situ observations

NASA Astrophysics Data System (ADS)

Maul, George A.; Hansen, Donald V.; Bravo, Nicolas J.

During the 1986-1989 Exact Repeat Mission (ERM) of GEOSAT, in-situ observations of sea level at Clipperton Island (10°N/109°W) and satellite-tracked free-drifting drogued buoys in the eastern tropical Pacific Ocean are concurrently available. A map of the standard deviations of GEOSAT sea surface heights (2.9 years) shows a variance maximum along ˜12°N from Central America, past Clipperton to ˜160°W. Sea floor pressure gauge observations from a shallow (10m depth) site on Clipperton Island and an ERM crossover point in deep water nearby show a correlation of r = 0.76 with a residual of ±6.7 cm RMS. Approximately 17% of the difference (GEOSAT minus sea level) is characterized by a 4 cm amplitude 0° phase annual harmonic, which is probably caused by unaccounted-for tropospheric water vapor affecting the altimeter and/or ERM orbit error removal. Wintertime anticyclonic mesoscale eddies advecting past Clipperton Island each year have GEOSAT sea surface height and in-situ sea level signals of more than 30 cm, some of which are documented by the satellite-tracked drifters. Meridional profiles of the annual harmonic of zonal geostrophic current from GEOSAT and from the drifters both show synchronous maxima in the North Equatorial Countercurrent and the North Equatorial Current. Other Clipperton sea level maxima seen during late spring of each year may involve anticyclonic vortices formed along Central America the previous winter.

Orion Heat Shield Manufacturing Producibility Improvements for the EM-1 Flight Test Program

NASA Technical Reports Server (NTRS)

Koenig, William J.; Stewart, Michael; Harris, Richard F.

2018-01-01

This paper describes how the ORION program is incorporating improvements in the heat shield design and manufacturing processes reducing programmatic risk and ensuring crew safety in support of NASA's Exploration missions. The approach for the EFT-1 heat shield utilized a low risk Apollo heritage design and manufacturing process using an Avcoat TPS ablator with a honeycomb substrate to provide a one piece heat shield to meet the mission re-entry heating environments. The EM-1 mission will have additional flight systems installed to fly to the moon and return to Earth. Heat shield design and producibility improvements have been incorporated in the EM-1 vehicle to meet deep space mission requirements. The design continues to use the Avcoat material, but in a block configuration to enable improvements in consistant and repeatable application processes using tile bonding experience developed on the Space Shuttle Transportation System Program.

Optimizing Aerobot Exploration of Venus

NASA Astrophysics Data System (ADS)

Ford, Kevin S.

1997-03-01

Venus Flyer Robot (VFR) is an aerobot; an autonomous balloon probe designed for remote exploration of Earth's sister planet in 2003. VFR's simple navigation and control system permits travel to virtually any location on Venus, but it can survive for only a limited duration in the harsh Venusian environment. To help address this limitation, we develop: (1) a global circulation model that captures the most important characteristics of the Venusian atmosphere; (2) a simple aerobot model that captures thermal restrictions faced by VFR at Venus; and (3) one exact and two heuristic algorithms that, using abstractions (1) and (2), construct routes making the best use of VFR's limited lifetime. We demonstrate this modeling by planning several small example missions and a prototypical mission that explores numerous interesting sites recently documented in the plane tary geology literature.

Optimizing Aerobot Exploration of Venus

NASA Technical Reports Server (NTRS)

Ford, Kevin S.

1997-01-01

Venus Flyer Robot (VFR) is an aerobot; an autonomous balloon probe designed for remote exploration of Earth's sister planet in 2003. VFR's simple navigation and control system permits travel to virtually any location on Venus, but it can survive for only a limited duration in the harsh Venusian environment. To help address this limitation, we develop: (1) a global circulation model that captures the most important characteristics of the Venusian atmosphere; (2) a simple aerobot model that captures thermal restrictions faced by VFR at Venus; and (3) one exact and two heuristic algorithms that, using abstractions (1) and (2), construct routes making the best use of VFR's limited lifetime. We demonstrate this modeling by planning several small example missions and a prototypical mission that explores numerous interesting sites recently documented in the plane tary geology literature.

A fast exact simulation method for a class of Markov jump processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yao, E-mail: yaoli@math.umass.edu; Hu, Lili, E-mail: lilyhu86@gmail.com

2015-11-14

A new method of the stochastic simulation algorithm (SSA), named the Hashing-Leaping method (HLM), for exact simulations of a class of Markov jump processes, is presented in this paper. The HLM has a conditional constant computational cost per event, which is independent of the number of exponential clocks in the Markov process. The main idea of the HLM is to repeatedly implement a hash-table-like bucket sort algorithm for all times of occurrence covered by a time step with length τ. This paper serves as an introduction to this new SSA method. We introduce the method, demonstrate its implementation, analyze itsmore » properties, and compare its performance with three other commonly used SSA methods in four examples. Our performance tests and CPU operation statistics show certain advantages of the HLM for large scale problems.« less

Efficient Exact Inference With Loss Augmented Objective in Structured Learning.

PubMed

Bauer, Alexander; Nakajima, Shinichi; Muller, Klaus-Robert

2016-08-19

Structural support vector machine (SVM) is an elegant approach for building complex and accurate models with structured outputs. However, its applicability relies on the availability of efficient inference algorithms--the state-of-the-art training algorithms repeatedly perform inference to compute a subgradient or to find the most violating configuration. In this paper, we propose an exact inference algorithm for maximizing nondecomposable objectives due to special type of a high-order potential having a decomposable internal structure. As an important application, our method covers the loss augmented inference, which enables the slack and margin scaling formulations of structural SVM with a variety of dissimilarity measures, e.g., Hamming loss, precision and recall, Fβ-loss, intersection over union, and many other functions that can be efficiently computed from the contingency table. We demonstrate the advantages of our approach in natural language parsing and sequence segmentation applications.

Sentinel-3 coverage-driven mission design: Coupling of orbit selection and instrument design

NASA Astrophysics Data System (ADS)

Cornara, S.; Pirondini, F.; Palmade, J. L.

2017-11-01

The first satellite of the Sentinel-3 series was launched in February 2016. Sentinel-3 payload suite encompasses the Ocean and Land Colour Instrument (OLCI) with a swath of 1270 km, the Sea and Land Surface Temperature Radiometer (SLSTR) yielding a dual-view scan with swaths of 1420 km (nadir) and 750 km (oblique view), the Synthetic Aperture Radar Altimeter (SRAL) working in Ku-band and C-band, and the dual-frequency Microwave Radiometer (MWR). In the early stages of mission and system design, the main driver for the Sentinel-3 reference orbit selection was the requirement to achieve a revisit time of two days or less globally over ocean areas with two satellites (i.e. 4-day global coverage with one satellite). The orbit selection was seamlessly coupled with the OLCI instrument design in terms of field of view (FoV) definition driven by the observation zenith angle (OZA) and sunglint constraints applied to ocean observations. The criticality of the global coverage requirement for ocean monitoring derives from the sunglint phenomenon, i.e. the impact on visible channels of the solar ray reflection on the water surface. This constraint was finally overcome thanks to the concurrent optimisation of the orbit parameters, notably the Local Time at Descending Node (LTDN), and the OLCI instrument FoV definition. The orbit selection process started with the identification of orbits with short repeat cycle (2-4 days), firstly to minimise the time required to achieve global coverage with existing constraints, and then to minimise the swath required to obtain global coverage and the maximum required OZA. This step yielded the selection of a 4-day repeat cycle orbit, thus allowing 2-day coverage with two adequately spaced satellites. Then suitable candidate orbits with higher repeat cycles were identified in the proximity of the selected altitudes and the reference orbit was ultimately chosen. Rationale was to keep the swath for global coverage as close as possible to the previous optimum value, but to tailor the repeat cycle length (i.e. the ground-track grid) to optimise the topography mission performances. The final choice converged on the sun-synchronous orbit 14 + 7/27, reference altitude ∼800 km, LTDN = 10h00. Extensive coverage analyses were carried out to characterise the mission performance and the fulfilment of the requirements, encompassing revisit time, number of acquisitions, observation viewing geometry and swath properties. This paper presents a comprehensive overview of the Sentinel-3 orbit selection, starting from coverage requirements and highlighting the close interaction with the instrument design activity.

Leveraging Existing Mission Tools in a Re-Usable, Component-Based Software Environment

NASA Technical Reports Server (NTRS)

Greene, Kevin; Grenander, Sven; Kurien, James; z,s (fshir. z[orttr); z,scer; O'Reilly, Taifun

2006-01-01

Emerging methods in component-based software development offer significant advantages but may seem incompatible with existing mission operations applications. In this paper we relate our positive experiences integrating existing mission applications into component-based tools we are delivering to three missions. In most operations environments, a number of software applications have been integrated together to form the mission operations software. In contrast, with component-based software development chunks of related functionality and data structures, referred to as components, can be individually delivered, integrated and re-used. With the advent of powerful tools for managing component-based development, complex software systems can potentially see significant benefits in ease of integration, testability and reusability from these techniques. These benefits motivate us to ask how component-based development techniques can be relevant in a mission operations environment, where there is significant investment in software tools that are not component-based and may not be written in languages for which component-based tools even exist. Trusted and complex software tools for sequencing, validation, navigation, and other vital functions cannot simply be re-written or abandoned in order to gain the advantages offered by emerging component-based software techniques. Thus some middle ground must be found. We have faced exactly this issue, and have found several solutions. Ensemble is an open platform for development, integration, and deployment of mission operations software that we are developing. Ensemble itself is an extension of an open source, component-based software development platform called Eclipse. Due to the advantages of component-based development, we have been able to vary rapidly develop mission operations tools for three surface missions by mixing and matching from a common set of mission operation components. We have also had to determine how to integrate existing mission applications for sequence development, sequence validation, and high level activity planning, and other functions into a component-based environment. For each of these, we used a somewhat different technique based upon the structure and usage of the existing application.

A concept for NASA's Mars 2016 astrobiology field laboratory.

PubMed

Beegle, Luther W; Wilson, Michael G; Abilleira, Fernando; Jordan, James F; Wilson, Gregory R

2007-08-01

The Mars Program Plan includes an integrated and coordinated set of future candidate missions and investigations that meet fundamental science objectives of NASA and the Mars Exploration Program (MEP). At the time this paper was written, these possible future missions are planned in a manner consistent with a projected budget profile for the Mars Program in the next decade (2007-2016). As with all future missions, the funding profile depends on a number of factors that include the exact cost of each mission as well as potential changes to the overall NASA budget. In the current version of the Mars Program Plan, the Astrobiology Field Laboratory (AFL) exists as a candidate project to determine whether there were (or are) habitable zones and life, and how the development of these zones may be related to the overall evolution of the planet. The AFL concept is a surface exploration mission equipped with a major in situ laboratory capable of making significant advancements toward the Mars Program's life-related scientific goals and the overarching Vision for Space Exploration. We have developed several concepts for the AFL that fit within known budget and engineering constraints projected for the 2016 and 2018 Mars mission launch opportunities. The AFL mission architecture proposed here assumes maximum heritage from the 2009 Mars Science Laboratory (MSL). Candidate payload elements for this concept were identified from a set of recommendations put forth by the Astrobiology Field Laboratory Science Steering Group (AFL SSG) in 2004, for the express purpose of identifying overall rover mass and power requirements for such a mission. The conceptual payload includes a Precision Sample Handling and Processing System that would replace and augment the functionality and capabilities provided by the Sample Acquisition Sample Processing and Handling system that is currently part of the 2009 MSL platform.

Global Optimization of Interplanetary Trajectories in the Presence of Realistic Mission Constraints

NASA Technical Reports Server (NTRS)

Hinckley, David; Englander, Jacob; Hitt, Darren

2015-01-01

Single trial evaluations Trial creation by Phase-wise GA-style or DE-inspired recombination Bin repository structure requires an initialization period Non-exclusionary Kill Distance Population collapse mechanic Main loop Creation Probabilistic switch between GA and DE creation types Locally optimize Submit to repository Repeat.

CAPE-2 Cubesat - ELaNa IV

NASA Image and Video Library

2016-07-25

CAPE-2: Cajun Advanced Picosatellite Experiment – ELaNa IV CAPE-2 was developed by students from the University of Louisiana Lafayette to engage, inspire and educate K-12 students to encourage them to pursue STEM careers. The secondary focus is the technology demonstration of deployed solar panels to support the following payloads: text to speech, voice repeater, tweeting, email, file transfer and data collection from buoys. Launched by NASA’s CubeSat Launch Initiative on the ELaNa IV mission as an auxiliary payload aboard the U.S. Air Force-led Operationally Responsive Space (ORS-3) Mission on November 19, 2013.

Final Phase Flight Performance and Touchdown Time Assessment of TDV in RLV-TD HEX-01 Mission

NASA Astrophysics Data System (ADS)

Yadav, Sandeep; Jayakumar, M.; Nizin, Aziya; Kesavabrahmaji, K.; Shyam Mohan, N.

2017-12-01

RLV-TD HEX-01 mission was configured as a precursor flight to actual two stages to orbit vehicle. In this mission RLV-TD was designed as a two stage vehicle for demonstrating the hypersonic flight of a winged body vehicle at Mach No. 5. One of the main objectives of this mission was to generate data for better understanding of new technologies required to design the future vehicle. In this mission, the RLV-TD vehicle was heavily instrumented to get data related to performance of different subsystems. As per the mission design, RLV-TD will land in sea after flight duration of 700 s and travelling a distance of nearly 500 km in Bay of Bengal from the launch site for a nominal trajectory. The visibility studies for telemetry data of vehicle for the nominal and off nominal trajectories were carried out. Based on that, three ground stations were proposed for the telemetry data reception (including one in sea). Even with this scheme it was seen that during the final phase of the flight there will not be any ground station visible to the flight due to low elevation. To have the mission critical data during final phase of the flight, telemetry through INSAT scheme was introduced. During the end of the mission RLV-TD will be landing in the sea on a hypothetical runway. To know the exact time of touchdown for the flight in sea, there was no direct measurement available. Simultaneously there were all chances of losing ground station visibility just before touchdown, making it difficult to assess flight performance during that phase. In this work, telemetry and instrumentation scheme of RLV-TD HEX-01 mission is discussed with an objective to determine the flight performance during the final phase. Further, using various flight sensor data the touchdown time of TDV is assessed for this mission.

Not just passengers: pigeons, Columba livia, can learn homing routes while flying with a more experienced conspecific.

PubMed

Pettit, Benjamin; Flack, Andrea; Freeman, Robin; Guilford, Tim; Biro, Dora

2013-01-07

For animals that travel in groups, the directional choices of conspecifics are potentially a rich source of information for spatial learning. In this study, we investigate how the opportunity to follow a locally experienced demonstrator affects route learning by pigeons over repeated homing flights. This test of social influences on navigation takes advantage of the individually distinctive routes that pigeons establish when trained alone. We found that pigeons learn routes just as effectively while flying with a partner as control pigeons do while flying alone. However, rather than learning the exact route of the demonstrator, the paired routes shifted over repeated flights, which suggests that the birds with less local experience also took an active role in the navigational task. The efficiency of the original routes was a key factor in how far they shifted, with less efficient routes undergoing the greatest changes. In this context, inefficient routes are unlikely to be maintained through repeated rounds of social transmission, and instead more efficient routes are achieved because of the interaction between social learning and information pooling.

ProGeRF: Proteome and Genome Repeat Finder Utilizing a Fast Parallel Hash Function

PubMed Central

Moraes, Walas Jhony Lopes; Rodrigues, Thiago de Souza; Bartholomeu, Daniella Castanheira

2015-01-01

Repetitive element sequences are adjacent, repeating patterns, also called motifs, and can be of different lengths; repetitions can involve their exact or approximate copies. They have been widely used as molecular markers in population biology. Given the sizes of sequenced genomes, various bioinformatics tools have been developed for the extraction of repetitive elements from DNA sequences. However, currently available tools do not provide options for identifying repetitive elements in the genome or proteome, displaying a user-friendly web interface, and performing-exhaustive searches. ProGeRF is a web site for extracting repetitive regions from genome and proteome sequences. It was designed to be efficient, fast, and accurate and primarily user-friendly web tool allowing many ways to view and analyse the results. ProGeRF (Proteome and Genome Repeat Finder) is freely available as a stand-alone program, from which the users can download the source code, and as a web tool. It was developed using the hash table approach to extract perfect and imperfect repetitive regions in a (multi)FASTA file, while allowing a linear time complexity. PMID:25811026

Intraindividual variability of boldness is repeatable across contexts in a wild lizard.

PubMed

Highcock, Laura; Carter, Alecia J

2014-01-01

Animals do not behave in exactly the same way when repeatedly tested in the same context or situation, even once systematic variation, such as habituation, has been controlled for. This unpredictability is called intraindividual variability (IIV) and has been little studied in animals. Here we investigated how IIV in boldness (estimated by flight initiation distances) changed across two seasons--the dry, non-breeding season and the wet, breeding season--in a wild population of the Namibian rock agama, Agama planiceps. We found significant differences in IIV both between individuals and seasons, and IIV was higher in the wet season, suggesting plasticity in IIV. Further, IIV was highly repeatable (r = 0.61) between seasons and we found strong negative correlations between consistent individual differences in flight initiation distances, i.e. their boldness, and individuals' IIVs. We suggest that to understand personality in animals, researchers should generate a personality 'profile' that includes not only the relative level of a trait (i.e. its personality), but also its plasticity and variability under natural conditions.

Moltke’s Mission Command Philosophy in the Twenty-First Century: Fallacy or Verity?

DTIC Science & Technology

2012-06-08

the first place and then giving accident exactly, almost mathematically, its place in one’s calculations. It is upon this point that one must not...deceive oneself, and yet a decimal point more or less may change all. Now this apportioning of accident and science cannot get into any head except that...of a genius. . . . Accident , hazard, chance, call it what you may-a mystery to ordinary minds- becomes a reality to superior men. ―Claire de

Effects of shade tab arrangement on the repeatability and accuracy of shade selection.

PubMed

Yılmaz, Burak; Yuzugullu, Bulem; Cınar, Duygu; Berksun, Semih

2011-06-01

Appropriate and repeatable shade matching using visual shade selection remains a challenge for the restorative dentist. The purpose of this study was to evaluate the effect of different arrangements of a shade guide on the repeatability and accuracy of visual shade selection by restorative dentists. Three Vitapan Classical shade guides were used for shade selection. Seven shade tabs from one shade guide were used as target shades for the testing (A1, A4, B2, B3, C2, C4, and D3); the other 2 guides were used for shade selection by the subjects. One shade guide was arranged according to hue and chroma and the second was arranged according to value. Thirteen male and 22 female restorative dentists were asked to match the target shades using shade guide tabs arranged in the 2 different orders. The sessions were performed twice with each guide in a viewing booth. Collected data were analyzed with Fisher's exact test to compare the accuracy and repeatability of the shade selection (α=.05). There were no significant differences observed in the accuracy or repeatability of the shade selection results obtained with the 2 different arrangements. When the hue/chroma-ordered shade guide was used, 58% of the shade selections were accurate. This ratio was 57.6% when the value-ordered shade guide was used. The observers repeated 55.5% of the selections accurately with the hue/chroma-ordered shade guide and 54.3% with the value-ordered shade guide. The accuracy and repeatability of shade selections by restorative dentists were similar when different arrangements (hue/chroma-ordered and value-ordered) of the Vitapan Classical shade guide were used. Copyright © 2011 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

Reasons for and functional results of repeated hip arthroscopy: A continuous prospective study of 17 revisions out of 295 primary hip arthroscopies at mean 28months' follow-up.

PubMed

Tissot, C; Merlini, L; Mercier, M; Bonin, N

2017-09-01

The rate of iterative arthroscopy has been increasing over the last decade as the technique has grown. The results of and reasons for these revision procedures, however, are not exactly known. We therefore conducted a prospective study to shed light on: 1) functional results and patient satisfaction following repeated arthroscopy, and 2) the relevant indications. Functional scores and patient satisfaction increase following repeated arthroscopy. MATERIALS AND METHOD: A single-center continuous prospective study without control group included patients undergoing repeated hip arthroscopy between September 2010 and September 2014, with a mean 28months' follow-up (median, 23.3months; range, 12-62months). Preoperative and follow-up functional assessment used the modified Harris hip, WOMAC and Christensen (NHAS) questionnaires, and a satisfaction scale. On etiological analysis, repeated arthroscopy was indicated if a cause of recurrent or persistent pain accessible to arthroscopic treatment was identified. Seventeen patients were included out of 295 primary arthroscopies (5.7%): 9 male, 8 female; median age, 29.6years (range, 16-48years). Indications for primary arthroscopy comprised 13 cases of femoroacetabular impingement, 3 labrum lesions with instability, 1 chondromatosis and 1 case of osteoarthritis. Eleven of the 17 primary lesions showed persistence, including 9 of the 13 cases of femoroacetabular impingement. There were 3 failures in 17 repeated arthroscopies. All functional scores improved, with a gain of 7 points (P<0.06) on modified Harris hip score, 25 points (P<0.0006) on WOMAC score, and 27 points (P<0.001) on NHAS score. Ten of the 17 patients were satisfied or very satisfied with the repeated arthroscopy (59%). Although less good than on primary arthroscopy, functional results on repeated hip arthroscopy were satisfactory in the short term. The main reason for repeated arthroscopy was persistence of initial abnormality due to insufficient treatment. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Launch and Assembly Reliability Analysis for Mars Human Space Exploration Missions

NASA Technical Reports Server (NTRS)

Cates, Grant R.; Stromgren, Chel; Cirillo, William M.; Goodliff, Kandyce E.

2013-01-01

NASA s long-range goal is focused upon human exploration of Mars. Missions to Mars will require campaigns of multiple launches to assemble Mars Transfer Vehicles in Earth orbit. Launch campaigns are subject to delays, launch vehicles can fail to place their payloads into the required orbit, and spacecraft may fail during the assembly process or while loitering prior to the Trans-Mars Injection (TMI) burn. Additionally, missions to Mars have constrained departure windows lasting approximately sixty days that repeat approximately every two years. Ensuring high reliability of launching and assembling all required elements in time to support the TMI window will be a key enabler to mission success. This paper describes an integrated methodology for analyzing and improving the reliability of the launch and assembly campaign phase. A discrete event simulation involves several pertinent risk factors including, but not limited to: manufacturing completion; transportation; ground processing; launch countdown; ascent; rendezvous and docking, assembly, and orbital operations leading up to TMI. The model accommodates varying numbers of launches, including the potential for spare launches. Having a spare launch capability provides significant improvement to mission success.

The 67P/Churyumov-Gerasimenko observation campaign in support of the Rosetta mission.

PubMed

Snodgrass, C; A'Hearn, M F; Aceituno, F; Afanasiev, V; Bagnulo, S; Bauer, J; Bergond, G; Besse, S; Biver, N; Bodewits, D; Boehnhardt, H; Bonev, B P; Borisov, G; Carry, B; Casanova, V; Cochran, A; Conn, B C; Davidsson, B; Davies, J K; de León, J; de Mooij, E; de Val-Borro, M; Delacruz, M; DiSanti, M A; Drew, J E; Duffard, R; Edberg, N J T; Faggi, S; Feaga, L; Fitzsimmons, A; Fujiwara, H; Gibb, E L; Gillon, M; Green, S F; Guijarro, A; Guilbert-Lepoutre, A; Gutiérrez, P J; Hadamcik, E; Hainaut, O; Haque, S; Hedrosa, R; Hines, D; Hopp, U; Hoyo, F; Hutsemékers, D; Hyland, M; Ivanova, O; Jehin, E; Jones, G H; Keane, J V; Kelley, M S P; Kiselev, N; Kleyna, J; Kluge, M; Knight, M M; Kokotanekova, R; Koschny, D; Kramer, E A; López-Moreno, J J; Lacerda, P; Lara, L M; Lasue, J; Lehto, H J; Levasseur-Regourd, A C; Licandro, J; Lin, Z Y; Lister, T; Lowry, S C; Mainzer, A; Manfroid, J; Marchant, J; McKay, A J; McNeill, A; Meech, K J; Micheli, M; Mohammed, I; Monguió, M; Moreno, F; Muñoz, O; Mumma, M J; Nikolov, P; Opitom, C; Ortiz, J L; Paganini, L; Pajuelo, M; Pozuelos, F J; Protopapa, S; Pursimo, T; Rajkumar, B; Ramanjooloo, Y; Ramos, E; Ries, C; Riffeser, A; Rosenbush, V; Rousselot, P; Ryan, E L; Santos-Sanz, P; Schleicher, D G; Schmidt, M; Schulz, R; Sen, A K; Somero, A; Sota, A; Stinson, A; Sunshine, J M; Thompson, A; Tozzi, G P; Tubiana, C; Villanueva, G L; Wang, X; Wooden, D H; Yagi, M; Yang, B; Zaprudin, B; Zegmott, T J

2017-07-13

We present a summary of the campaign of remote observations that supported the European Space Agency's Rosetta mission. Telescopes across the globe (and in space) followed comet 67P/Churyumov-Gerasimenko from before Rosetta's arrival until nearly the end of the mission in September 2016. These provided essential data for mission planning, large-scale context information for the coma and tails beyond the spacecraft and a way to directly compare 67P with other comets. The observations revealed 67P to be a relatively 'well-behaved' comet, typical of Jupiter family comets and with activity patterns that repeat from orbit to orbit. Comparison between this large collection of telescopic observations and the in situ results from Rosetta will allow us to better understand comet coma chemistry and structure. This work is just beginning as the mission ends-in this paper, we present a summary of the ground-based observations and early results, and point to many questions that will be addressed in future studies.This article is part of the themed issue 'Cometary science after Rosetta'. © 2017 The Author(s).

Sentinel-1 mission scientific exploitation activities

NASA Astrophysics Data System (ADS)

Desnos, Yves louis; Foumelis, Michael; Engdahl, Marcus

2017-04-01

The Sentinel-1 mission is the European Imaging Radar Observatory for the Copernicus joint initiative of the European Commission (EC) and the European Space Agency (ESA). Sentinel-1 mission is composed of a constellation of two satellites, Sentinel-1A and Sentinel-1B (launched in April 2014 and April 2016, respectively), sharing the same orbital plane and featuring a short repeat cycle of 6 days optimised for Synthetic Aperture Radar (SAR) interferometry science and applications. The full operation capacity was achieved after the completion of the Sentinel-1B in-orbit commissioning on 14 September 2016. Sentinel-1 data are freely available via the ESA's Sentinels Scientific Data Hub since October 2014. The data uptake by the science community has been unprecedented and numerous results have been published to date. The objective of the current paper is to provide a brief overview of the latest ESA activities, in the frame of the Scientific Exploitation of Operational Missions (SEOM) programme, aimed to facilitate the scientific exploitation of Sentinel-1 mission as well as discuss future opportunities for research.

Structures of ω repressors bound to direct and inverted DNA repeats explain modulation of transcription

PubMed Central

Weihofen, Wilhelm Andreas; Cicek, Aslan; Pratto, Florencia; Alonso, Juan Carlos; Saenger, Wolfram

2006-01-01

Repressor ω regulates transcription of genes required for copy number control, accurate segregation and stable maintenance of inc18 plasmids hosted by Gram-positive bacteria. ω belongs to homodimeric ribbon-helix-helix (RHH2) repressors typified by a central, antiparallel β-sheet for DNA major groove binding. Homodimeric ω2 binds cooperatively to promotors with 7 to 10 consecutive non-palindromic DNA heptad repeats (5′-A/TATCACA/T-3′, symbolized by →) in palindromic inverted, converging (→←) or diverging (←→) orientation and also, unique to ω2 and contrasting other RHH2 repressors, to non-palindromic direct (→→) repeats. Here we investigate with crystal structures how ω2 binds specifically to heptads in minimal operators with (→→) and (→←) repeats. Since the pseudo-2-fold axis relating the monomers in ω2 passes the central C–G base pair of each heptad with ∼0.3 Å downstream offset, the separation between the pseudo-2-fold axes is exactly 7 bp in (→→), ∼0.6 Å shorter in (→←) but would be ∼0.6 Å longer in (←→). These variations grade interactions between adjacent ω2 and explain modulations in cooperative binding affinity of ω2 to operators with different heptad orientations. PMID:16528102

Nanomaterial Based Sensors for NASA Missions

NASA Technical Reports Server (NTRS)

Koehne, Jessica E.

2016-01-01

Nanomaterials such as carbon nanotubes (CNTs), carbon nanofibers (CNFs), graphene and metal nanowires have shown interesting electronic properties and therefore have been pursued for a variety of space applications requiring ultrasensitive and light-weight sensor and electronic devices. We have been pursuing development of chemical and biosensors using carbon nanotubes and carbon nanofibers for the last several years and this talk will present the benefits of nanomaterials these applications. More recently, printing approaches to manufacturing these devices have been explored as a strategy that is compatible to a microgravity environment. Nanomaterials are either grown in house or purchased and processed as electrical inks. Chemical modification or coatings are added to the nanomaterials to tailor the nanomaterial to the exact application. The development of printed chemical sensors and biosensors will be discussed for applications ranging from crew life support to exploration missions.

Mission Performance of the GLAS Thermal Control System - 7 Years In Orbit

NASA Technical Reports Server (NTRS)

Grob, Eric W.

2010-01-01

ICESat (Ice, Cloud and land Elevation Satellite) was launched in 2003 carrying a single science instrument - the Geoscience Laser Altimeter System (GLAS). Its primary mission was to measure polar ice thickness. The GLAS thermal control architecture utilized propylene Loop Heat Pipe (LHP) technology to provide selectable and stable temperature control for the lasers and other electronics over a widely varying mission thermal environment. To minimize expected degradation of the radiators, Optical Solar Reflectors (OSRs) were used for both LHP radiators to minimize degradation caused by UV exposure in the various spacecraft attitudes necessary throughout the mission. Developed as a Class C mission, with selective redundancy, the thermal architecture was single st ring, except for temperature sensors used for heater control during normal operations. Although originally planned for continuous laser operations over the nominal three year science mission, laser anomalies limited operations to discrete measurement campaigns repeated throughout the year. For trending of the science data, these periods were selected to occur at approximately the same time each year, which resulted in operations during similar attitudes and beta angles. Despite the laser life issues, the LHPs have operated nearly continuously over this time, being non-operational for only brief periods. Using mission telemetry, this paper looks at the performance of the thermal subsystem during these periods and provides an assessment of radiator degradation over the mission lifetime.

Global-scale Observations of the Limb and Disk (GOLD) Mission - A New Approach to Ultraviolet Remote Sensing of Earth's Space Environment

NASA Astrophysics Data System (ADS)

Eastes, R.; McClintock, W. E.; Anderson, D. N.; Andersson, L.; Burns, A. G.; Codrescu, M.; Daniell, R. E.; England, S.; Krywonos, A.; Lumpe, J. D.; Richmond, A. D.; Rusch, D. W.; Siegmund, O.; Solomon, S. C.; Strickland, D. J.; Woods, T. N.; Budzien, S. A.; Dymond, K.; Eparvier, F. G.; Jones, S.; Martinis, C. R.; Oberheide, J.; Talaat, E. R.; Barrett, R.; Harvey, J.

2016-12-01

The GOLD mission of opportunity will fly a far ultraviolet imaging spectrograph in geostationary (GEO) orbit as a hosted payload. The mission is scheduled for launch in late 2017 on SES-14, a commercial communications satellite that will be stationed over eastern South America at 47.5 degrees west longitude. GOLD is on schedule to be the first NASA science mission to fly as a hosted payload on a commercial communications satellite. The GOLD imager has two identical channels. Each channel can scan the full disk at a 30 minute cadence, making spectral images of Earth's UV emission from 132 to 162 nm, as well as make a measurement on the Earth's limb. Remote sensing techniques that have been proven on previous Low Earth Orbit (LEO) missions will be used to derive fundamental parameters for the neutral and ionized space environment. Parameters that will be derived include composition (O/N2 ratio) and temperature of the neutral atmosphere on the dayside disk. On the nightside, peak electron densities will be obtained in the low latitude ionosphere. Similar imaging of atmospheric composition from LEO, at only a daily cadence for revisiting locations, has already provided many new insights into the behavior of Earth's Thermosphere-Ionosphere (T-I) system. From geostationary orbit, GOLD can repeatedly image the same geographic locations over most of the hemisphere at a cadence comparable to that of the T-I system (order of an hour). Such time resolution and spatial coverage will allow the mission to track the changes due to geomagnetic storms, variations in solar extreme ultraviolet radiation, and forcing from the lower atmosphere. In addition to providing a new perspective by being able to repeatedly remotely sense the same hemisphere at a high cadence, GOLD's simultaneous measurements of not only composition but also temperatures across the disk will provide a valuable, new parameter for understanding of how the T-I system responds to forcing from the sun and the lower atmosphere.

Near-Infrared Monitoring of Volatiles in Frozen Lunar Simulants While Drilling

NASA Technical Reports Server (NTRS)

Roush, Ted L.; Colaprete, Anthony; Elphic, Richard C.; Forgione, Joshua; White, Bruce; McMurray, Robert; Cook, Amanda M.; Bielawski, Richard; Fritzler, Erin L.; Thompson, Sarah J.;

Space Adaptation Back Pain: A Retrospective Study

NASA Technical Reports Server (NTRS)

Kerstman, Eric

2009-01-01

Astronaut back pain is frequently reported in the early phase of space flight as they adapt to microgravity. The epidemiology of space adaptation back pain (SABP) has not been well established. This presentation seeks to determine the exact incidence of SABP among astronauts, develop a case definition of SABP, delineate the nature and pattern of SABP, review available treatments and their effectiveness in relieving SABP; and identify any operational impact of SABP. A retrospective review of all available mission medical records of astronauts in the U.S. space program was performed. It was revealed that the incidence of SABP has been determined to be 53% among astronauts in the U.S. space program; most cases of SABP are mild, self-limited, or respond to available treatment; there are no currently accepted preventive measures for SABP; it is difficult to predict who will develop SABP; the precise mechanism and spinal structures responsible for SABP are uncertain; there was no documented evidence of direction operational mission impact related to SABP; and, that there was the potential for mission impact related to uncontrolled pain, sleep disturbance, or the adverse side effects pf anti-inflammatory medications

Establishment of design criteria for acceptable failure modes and fail safe considerations for the space shuttle structural system

NASA Technical Reports Server (NTRS)

Westrup, R. W.

1971-01-01

The application of general design approaches for preventing failures due to repeated load cycles is briefly discussed. Program objective, mission requirements, and structural design criteria are summarized. Discrete structural elements and associated sections were selected for detailed strength, fatigue, and fracture mechanics investigations.

Effects of spaceflight on rat pituitary cell function: Preflight and flight experiment for pituitary gland study on COSMOS, 1989

NASA Technical Reports Server (NTRS)

Hymer, Wesley C.

1990-01-01

The secretory capacity of growth hormone (GH) and prolactin (PRL) cells prepared from rats flown in space on the 12.5 day mission of Cosmos 1887 and the 14 day mission of Cosmos 2044 was evaluated in several post-flight tests on Earth. The results showed statistically significant and repeatable decrements in hormone release, especially when biological assays (rather than immunological assays) were used in the tests. Significant and repeatable intracellular changes in GH cells from the flight animals were also found; most important were increases in the GH-specific cytoplasmic staining intensities and cytoplasmic areas occupied by hormore. Tail suspension of rats for 14 days, an established model for mimicking musculo-skeletal changes seen in spaceflown rats, results in some changes in GH and PRL cell function that were similar to those from spaceflown animals. Our results add to a growing body of data that described deconditioning of physiological systems in spaceflight and provide insights into the time frame that might be required for readaptation of the GH/PRL cell system upon return to Earth.

Space Astrometry Science with Gaia

NASA Astrophysics Data System (ADS)

Mignard, Francois

2009-05-01

The European Space Agency has formally approved in spring 2006 the overall funding of its next space astrometry mission Gaia scheduled for a launch in spring 2012. The mission will create an extraordinarily precise three-dimensional map of about one billion stars throughout our Galaxy and beyond from repeated astrometric and photometric observations over about five years. End-of-mission expected accuracies in wide angle astrometry fall in the 7-25 muas range for start brighter than 15 mag and sub-mas at the faint end (20 mag). The science covered by Gaia is broad and extends from galactic and stellar astrophysics to solar systems dynamics and physics and the construction of an inertial frame in the visible with extragalactic sources. Fundamental physics with general relativity testing will also be a major product of the mission. In the presentation I will overview the Gaia science case, stressing more specifically the astrometric side of the expected results and provide few hints on the overall organisation of the data analysis entrusted to the Data Processing and Analysis Consortium (DPAC).

Oceans in the Outer Solar System: Future Exploration of Europa, Titan, and Enceladus

NASA Astrophysics Data System (ADS)

Johnson, T.; Clark, K.; Cutts, J.; Lunine, J.; Pappalardo, R.; Reh, K.

Observational and theoretical evidence points to water-rich oceans or seas within several of the icy satellites of the outer planets, notably Europa and Enceladus, and hydrocarbon reservoirs within Titan. Here we report on concepts for future studies of these fascinating targets of high astrobiological relevance. Europa Exploration: Post-Galileo exploration of Europa presents several major technical challenges. We argue that four recent investments in technology and research allow a flagship mission class Europa exploration that relies on demonstrated technologies and achieves the high level science objectives. 1. Mass and Trip Time: Utilizing indirect Earth gravity assist, trajectories allows ˜2000 - 3000 kg dry mass, permitting ˜150 - 200 kg of science payload. 2. Radiation Tolerant Electronics: A significant program of radiation hard technology development has been done by NASA. The necessary radiation-tolerant elements are now ready for flight. 3. Science Mission: The science mission would last approximately two years, with a Jupiter system science phase of ˜1.5 yr and a 90 day nominal orbital mission at Europa, with significant probability of functioning much longer. 4. Planetary Protection: The ultimate fate of an orbiter will be impact with Europa. Planetary protection requirements will be met by radiation sterilization during the primary mission for most external and unshielded internal surfaces, combined with pre-launch sterilization of shielded components. We conclude that a flagship class Europa mission can now be developed relying on existing technologies, having significant scientific capability. Titan and Enceladus Exploration: Remarkable discoveries by the Cassini/Huygens related to hydrocarbons at Titan and water vapor geysering at Enceladus demand follow-up of these astrobiologically relevant worlds by future missions. An aerial platform capable of observing the surface of Titan from beneath the obscuring cloud cover and descending repeatedly to the surface, can offer a powerful scientific capability. Taking advantage of both the density and cold temperature of the atmosphere of Titan a hot-air balloon implementation provides long duration operation at a very modest cost in terms of energy input. A Saturn orbiter making repeated encounters of Titan and Enceladus in a so-called cycler orbit can carry out new science at Enceladus while also providing high bandwidth downlink communications for the aerial platform.

User evaluation of a GUI for controlling an autonomous persistent surveillance team

NASA Astrophysics Data System (ADS)

Scerri, Paul; Owens, Sean; Sycara, Katia; Lewis, Michael

2010-04-01

In future military missions, there will be many sensor assets collecting much important information about the environment. User control over surveillance assets is important to ensure that the specific data collected is appropriate for the current mission. Unfortunately, previous work has shown that individual users cannot effectively control more than about four assets, even if the assets have significant autonomy. In the ACCAST project, we hypothesized that by including autonomous teamwork between the assets and allowing users to interact by describing what the team as a whole and specific sub-teams should do, we could dramatically scale up the number of assets an individual user could effectively control. In this paper, we present the results of an experiment where users controlled up to 30 autonomous assets performing a complex mission. The assets autonomously worked together using sophisticated teamwork and the user could tell sub-teams to execute team oriented plans which described the steps required to achieve a team objective without describing exactly which asset performed which role and without having to specify how the team should handle routine information sharing, communications and failure circumstances. The users, soldiers from Fort Benning, were surprisingly good at managing the assets and were all able to complete the complex mission with extremely low friendly and civilian casualties.

Evaluation of JGM 2 geopotential errors from geosat, TOPEX/poseidon and ERS-1 crossover altimetry

NASA Astrophysics Data System (ADS)

Wagner, C. A.; Klokocník, J.; Tai, C. K.

1995-08-01

World-ocean distribution of the crossover altimetry data from Geosat, TOPEX/Poseidon (T/P) and the ERS 1 missions have provided strong independent evidence that NASA's/CSR's JGM 2 geopotential model (70 x 70 in spherical harmonics) yields accurate radial ephemerides for these satellites. In testing the sea height crossover differences found from altimetry and JGM 2 orbits for these satellites, we have used the sea height differences themselves (of ascending minus descending passes averaged at each location over many exact repeat cycles) and the Lumped Latitude Coefficients (LLC) derived from them. For Geosat we find the geopotential-induced LLC errors (exclusive of non-gravitational and initial state discrepancies) mostly below 6 cm, for TOPEX the corresponding errors are usually below 2 cm, and for ERS 1 (35-day cycle) they are generally belo2 5 cm. In addition, we have found that these observations agree well overall with predictions of accuracy derived from the JGM 2 variance-covariance matrix; the corresponding projected LLC errors for Geosat, T/P, and ERS 1 are usually between 1 and 4 cm, 1 - 2 cm, and 1 - 4 cm, respectively (they depend on the filtering of long-periodic perturbations and on the order of the LLC). This agreement is especially impressive for ERS 1 since no data of any kind from this mission was used in forming JGM 2. The observed crossover differences for Geosat, T/P and ERS 1 are 8, 3, and 11 cm (rms), respectively. These observations also agree well with prediction of accuracy derived from the JGM 2 variance-covariance matrix; the corresponding projected crossover errors for Geosat and T/P are 8 cm and 2.3 cm, respectively. The precision of our mean difference observations is about 3 cm for Geosat (approx. 24,000 observations), 1.5 cm for T/P (approx. 6,000 observations) and 5 cm for ERS 1 (approx. 44,000 observations). Thus, these ``global'' independent data should provide a valuable new source for improving geopotential models. Our results show the need for further correction of the low order JGM 2 geopotential as well as certain resonant orders for all 3 satellites.

Calculating the mounting parameters for Taylor Spatial Frame correction using computed tomography.

PubMed

Kucukkaya, Metin; Karakoyun, Ozgur; Armagan, Raffi; Kuzgun, Unal

2011-07-01

The Taylor Spatial Frame uses a computer program-based six-axis deformity analysis. However, there is often a residual deformity after the initial correction, especially in deformities with a rotational component. This problem can be resolved by recalculating the parameters and inputting all new deformity and mounting parameters. However, this may necessitate repeated x-rays and delay treatment. We believe that error in the mounting parameters is the main reason for most residual deformities. To prevent these problems, we describe a new calculation technique for determining the mounting parameters that uses computed tomography. This technique is especially advantageous for deformities with a rotational component. Using this technique, exact calculation of the mounting parameters is possible and the residual deformity and number of repeated x-rays can be minimized. This new technique is an alternative method to accurately calculating the mounting parameters.

Fundamental limits of repeaterless quantum communications

PubMed Central

Pirandola, Stefano; Laurenza, Riccardo; Ottaviani, Carlo; Banchi, Leonardo

2017-01-01

Quantum communications promises reliable transmission of quantum information, efficient distribution of entanglement and generation of completely secure keys. For all these tasks, we need to determine the optimal point-to-point rates that are achievable by two remote parties at the ends of a quantum channel, without restrictions on their local operations and classical communication, which can be unlimited and two-way. These two-way assisted capacities represent the ultimate rates that are reachable without quantum repeaters. Here, by constructing an upper bound based on the relative entropy of entanglement and devising a dimension-independent technique dubbed ‘teleportation stretching', we establish these capacities for many fundamental channels, namely bosonic lossy channels, quantum-limited amplifiers, dephasing and erasure channels in arbitrary dimension. In particular, we exactly determine the fundamental rate-loss tradeoff affecting any protocol of quantum key distribution. Our findings set the limits of point-to-point quantum communications and provide precise and general benchmarks for quantum repeaters. PMID:28443624

Non-convulsive status epilepticus.

PubMed Central

Stores, G; Zaiwalla, Z; Styles, E; Hoshika, A

1995-01-01

The clinical, electrographic and reported neuropsychological features of 50 children with non-convulsive status epilepticus (NCSE) were reviewed and the children's progress followed for one to five years. NCSE occurred in a variety of epilepsies, especially the Lennox-Gastaut syndrome. Clinical manifestations ranged from obvious mental deterioration to subtle changes. The condition had often been overlooked or misinterpreted and many children had experienced repeated episodes over long periods. Following diagnosis, immediate treatment was often not attempted or was not successful. Further episodes of NCSE occurred in the majority of children during the follow up period. Failure to recognise NCSE and to treat episodes promptly, and the high rate of recurrence, is of particular concern in view of fears that repeated exposure to this condition might be brain damaging. At least 28 children in the present series showed evidence of intellectual or educational deterioration over the period during which NCSE had occurred, although the exact cause was difficult to determine. PMID:7574851

Fundamental limits of repeaterless quantum communications.

PubMed

Pirandola, Stefano; Laurenza, Riccardo; Ottaviani, Carlo; Banchi, Leonardo

2017-04-26

Quantum communications promises reliable transmission of quantum information, efficient distribution of entanglement and generation of completely secure keys. For all these tasks, we need to determine the optimal point-to-point rates that are achievable by two remote parties at the ends of a quantum channel, without restrictions on their local operations and classical communication, which can be unlimited and two-way. These two-way assisted capacities represent the ultimate rates that are reachable without quantum repeaters. Here, by constructing an upper bound based on the relative entropy of entanglement and devising a dimension-independent technique dubbed 'teleportation stretching', we establish these capacities for many fundamental channels, namely bosonic lossy channels, quantum-limited amplifiers, dephasing and erasure channels in arbitrary dimension. In particular, we exactly determine the fundamental rate-loss tradeoff affecting any protocol of quantum key distribution. Our findings set the limits of point-to-point quantum communications and provide precise and general benchmarks for quantum repeaters.

Modular probes for enriching and detecting complex nucleic acid sequences

NASA Astrophysics Data System (ADS)

Wang, Juexiao Sherry; Yan, Yan Helen; Zhang, David Yu

2017-12-01

Complex DNA sequences are difficult to detect and profile, but are important contributors to human health and disease. Existing hybridization probes lack the capability to selectively bind and enrich hypervariable, long or repetitive sequences. Here, we present a generalized strategy for constructing modular hybridization probes (M-Probes) that overcomes these challenges. We demonstrate that M-Probes can tolerate sequence variations of up to 7 nt at prescribed positions while maintaining single nucleotide sensitivity at other positions. M-Probes are also shown to be capable of sequence-selectively binding a continuous DNA sequence of more than 500 nt. Furthermore, we show that M-Probes can detect genes with triplet repeats exceeding a programmed threshold. As a demonstration of this technology, we have developed a hybrid capture method to determine the exact triplet repeat expansion number in the Huntington's gene of genomic DNA using quantitative PCR.

Jet Propulsion Laboratory: Annual Report 2006

NASA Technical Reports Server (NTRS)

2007-01-01

Nothing is as gratifying in space exploration as when we are surprised by the unexpected. Much of our work progresses in an orderly way, from concept to plan to creation to finding. But now and then we are caught off-guard by something startlingly new, and it is these moments that make our hearts race and leave us with many of our most compelling memories. And 2006 was an exceptional year for the unforeseen. One of our orbiters shocked many with stark proof that liquid water, the seemingly long-gone force that reshaped so much of the scenery of Mars, still flows there today,at least in occasional bursts. Another spacecraft caught us by surprise with photos of Yellowstone-like geysers on one of Saturn's seemingly nondescript moons, Enceladus. A spaceborne observatory created to plumb the life histories of stars and galaxies showed off a completely unexpected talent when it revealed the day and night faces of a fire and ice planet far beyond our solar system 40 light-years away. A newly launched Earth observer revealed that the clouds that decorate our own planet are not what we thought them to be in many ways. Of course, not all of the high points of the year arrived on our doorstep in such unexpected ways. There was also great drama when missions came off exactly as planned, such as when Stardust's sample return capsule made a flawless landing in the Utah desert, bringing home samples of cometary and interstellar dust. Mars Reconnaissance Orbiter slipped into orbit around the red planet exactly as planned. Numerous other missions and technology programs likewise made great achievements during the year. In all, 17 spacecraft and six instruments were stationed across the solar system, studying our own world, other planets, comets and the deeper universe. All of these achievements were enabled by many teams and systems at the Laboratory. The Deep Space Network of communications complexes across three continents supported all of NASA's solar system missions, and several from our international partners, while looking ahead to reinvent itself for the future. Technologists were at work creating innovations both for NASA missions and terrestrial uses. JPL's community of scientific researchers was equally busy coordinating the science activities of our missions and pursuing independent investigations. None of this would be possible without the support of business and administrative teams dedicated to making the Laboratory's institutional environment as world-class as its technical face, or the public engagement specialists who bring the experience of space to the country's diverse publics. All of our missions in one way or another support our nation's Vision for Space Exploration, which envisages a gradually widening robotic and human presence across the solar system in the years ahead.

Mars Sample Return - Launch and Detection Strategies for Orbital Rendezvous

NASA Technical Reports Server (NTRS)

Woolley, Ryan C.; Mattingly, Richard L.; Riedel, Joseph E.; Sturm, Erick J.

2011-01-01

This study sets forth conceptual mission design strategies for the ascent and rendezvous phase of the proposed NASA/ESA joint Mars Sample Return Campaign. The current notional mission architecture calls for the launch of an acquisition/cache rover in 2018, an orbiter with an Earth return vehicle in 2022, and a fetch rover and ascent vehicle in 2024. Strategies are presented to launch the sample into a coplanar orbit with the Orbiter which facilitate robust optical detection, orbit determination, and rendezvous. Repeating ground track orbits exist at 457 and 572 km which provide multiple launch opportunities with similar geometries for detection and rendezvous.

Mars Sample Return: Launch and Detection Strategies for Orbital Rendezvous

NASA Technical Reports Server (NTRS)

Woolley, Ryan C.; Mattingly, Richard L.; Riedel, Joseph E.; Sturm, Erick J.

2011-01-01

This study sets forth conceptual mission design strategies for the ascent and rendezvous phase of the proposed NASA/ESA joint Mars Sample Return Campaign. The current notional mission architecture calls for the launch of an acquisition/ caching rover in 2018, an Earth return orbiter in 2022, and a fetch rover with ascent vehicle in 2024. Strategies are presented to launch the sample into a nearly coplanar orbit with the Orbiter which would facilitate robust optical detection, orbit determination, and rendezvous. Repeating ground track orbits existat 457 and 572 km which would provide multiple launch opportunities with similar geometries for detection and rendezvous.

Detecting elevation changes over mountain glaciers in Tibet and the Himalayas by TOPEX/Poseidon and Jason-2 radar altimeters: comparison with ICESat results

NASA Astrophysics Data System (ADS)

Hwang, C.; Cheng, Y. S.

2015-12-01

In most cases, mountain glaciers are narrow and situated over steep slopes. A laser-based altimeter such as ICESat has a small illuminated footprint at about 70 m, thus allowing to measure precise elevations over narrow mountain glaciers. However, unlike a typical radar altimeter mission, ICESat does not have repeat ground tracks (except in its early phase) to measure heights of a specific point at different times. Within a time span, usually a reference digital elevation model is used to compute height anomalies at ICESat's measurement sites over a designated area, which are then averaged to produce a representative height change (anomaly) in this area. In contrast, a radar altimeter such as TOPEX/Poseidon (TP; its follow-on missions are Jason-1 and -2), repeats its ground tracks at an even time interval (10 days for TP), but has a larger illuminated footprint than ICESat's (about 1 km or larger), making it difficult to measure precise elevations over narrow mountain glaciers. Here we demonstrate the potential of TP and Jason-2 radar altimeters in detecting elevation changes over mountain glaciers that are sufficiently wide and smooth. We select several glacier-covered sites in Mt. Tanggula (Tibet) and the Himalayas to experiment with methods that can generate precise height measurements from the two altimeters. Over the same spot, ranging errors due to slope, volume scattering and radar penetration can be common between repeat cycles, and may be reduced by differencing successive heights. We retracked radar waveforms and classify the surfaces using the SRTM-derived elevations. The effects of terrain and slope are reduced by fitting a surface to the height measurements from repeat cycles. We remove outlier heights and apply a smoothing filter to form final time series of glacier elevation change at the selected sites, which are compared with the results from ICESat (note the different mission times). Because TP and Jason-2 measure height changes every 10 days, clear annual and inter-annual oscillations of glacier heights are present in the resulting time series, in comparison to the unevenly sampled height changes from ICESat that do not show such oscillations. The rates of glacier elevation change from T/P and Jason-2 are mostly negative, but vary with locations and heights.

Using Equation-Free Computation to Accelerate Network-Free Stochastic Simulation of Chemical Kinetics.

PubMed

Lin, Yen Ting; Chylek, Lily A; Lemons, Nathan W; Hlavacek, William S

2018-06-21

The chemical kinetics of many complex systems can be concisely represented by reaction rules, which can be used to generate reaction events via a kinetic Monte Carlo method that has been termed network-free simulation. Here, we demonstrate accelerated network-free simulation through a novel approach to equation-free computation. In this process, variables are introduced that approximately capture system state. Derivatives of these variables are estimated using short bursts of exact stochastic simulation and finite differencing. The variables are then projected forward in time via a numerical integration scheme, after which a new exact stochastic simulation is initialized and the whole process repeats. The projection step increases efficiency by bypassing the firing of numerous individual reaction events. As we show, the projected variables may be defined as populations of building blocks of chemical species. The maximal number of connected molecules included in these building blocks determines the degree of approximation. Equation-free acceleration of network-free simulation is found to be both accurate and efficient.

A new type of exact arbitrarily inhomogeneous cosmology: evolution of deceleration in the flat homogeneous-on-average case

NASA Astrophysics Data System (ADS)

Hellaby, Charles

2012-01-01

A new method for constructing exact inhomogeneous universes is presented, that allows variation in 3 dimensions. The resulting spacetime may be statistically uniform on average, or have random, non-repeating variation. The construction utilises the Darmois junction conditions to join many different component spacetime regions. In the initial simple example given, the component parts are spatially flat and uniform, but much more general combinations should be possible. Further inhomogeneity may be added via swiss cheese vacuoles and inhomogeneous metrics. This model is used to explore the proposal, that observers are located in bound, non-expanding regions, while the universe is actually in the process of becoming void dominated, and thus its average expansion rate is increasing. The model confirms qualitatively that the faster expanding components come to dominate the average, and that inhomogeneity results in average parameters which evolve differently from those of any one component, but more realistic modelling of the effect will need this construction to be generalised.

Aspects of ESA s public outreach programme

NASA Astrophysics Data System (ADS)

Maree, H.

The Science Programme Communication Service is currently implementing a new policy to increase the overall public interest in ESA Science Programme by adopting new ways of promoting its activities, accordingly to the simple principle that "different target audiences have different needs". It is clear that the general public (i.e. "the man in the street" / "the average tax- payer") rarely has the knowledge and the background to understand what exactly a space mission is, what it does and why it does it ("Mission oriented approach"). The experience has shown that a space mission becomes "popular" amongst this target audience when the relevant communication is done by passing generic/bas ic/simple messages ("Thematic oriented approach"). The careful selection of adequate supports together with efficient distribution and promotion networks are also key parameters for success of the latter approach. One should also note that the overall objective of this new policy, is to raise people's interest in space in general. By presenting the information under the ESA brand, the public will start more and more to associate this brand and Europe to space exploration. Within the next twelve months, four scientific missions will be launched. Interestingly, tree of them (SMART-1, ROSETTA and MARS EXPRESS) offer a unique opportunity to implement the new communication policy under the single thematic : Europe is exploring the Solar System. Nevertheless, the study of the various mission profiles and their potential communication impact lead us to choose to reach out the general public primarily via the sub-thematic : Europe goes to Mars.

Starshade orbital maneuver study for WFIRST

NASA Astrophysics Data System (ADS)

Soto, Gabriel; Sinha, Amlan; Savransky, Dmitry; Delacroix, Christian; Garrett, Daniel

2017-09-01

The Wide Field Infrared Survey Telescope (WFIRST) mission, scheduled for launch in the mid-2020s will perform exoplanet science via both direct imaging and a microlensing survey. An internal coronagraph is planned to perform starlight suppression for exoplanet imaging, but an external starshade could be used to achieve the required high contrasts with potentially higher throughput. This approach would require a separately-launched occulter spacecraft to be positioned at exact distances from the telescope along the line of sight to a target star system. We present a detailed study to quantify the Δv requirements and feasibility of deploying this additional spacecraft as a means of exoplanet imaging. The primary focus of this study is the fuel use of the occulter while repositioning between targets. Based on its design, the occulter is given an offset distance from the nominal WFIRST halo orbit. Target star systems and look vectors are generated using Exoplanet Open-Source Imaging Simulator (EXOSIMS); a boundary value problem is then solved between successive targets. On average, 50 observations are achievable with randomly selected targets given a 30-day transfer time. Individual trajectories can be optimized for transfer time as well as fuel usage to be used in mission scheduling. Minimizing transfer time reduces the total mission time by up to 4.5 times in some simulations before expending the entire fuel budget. Minimizing Δv can generate starshade missions that achieve over 100 unique observations within the designated mission lifetime of WFIRST.

The Binary Asteroid in-situ Explorer (BASiX) Mission

NASA Astrophysics Data System (ADS)

Dissly, Richard; Scheeres, D. J.; Nilsen, E.; Roark, S.; Frazier, W.; Bank, T.; Rosing, D.; Jordan, E.; BASiX Science Team

2010-10-01

The Binary Asteroid in-situ Explorer (BASiX) Mission represents the next phase of asteroid exploration, carrying out geophysical experiments by active engagement with an asteroid in a controlled and repeatable manner. BASiX will address new and timely scientific goals that address unresolved issues at the heart of our understanding of these bodies and which serve as barriers to their future exploration. A primary objective of the BASiX Mission is to determine the fundamental mechanical and strength properties of an asteroid through the creation of craters on the asteroid surface using calibrated charges. BASiX also takes advantage of these experiments to further understand the weathering and seismic properties of an asteroid. By carrying out these experiments at a binary Near Earth Asteroid (NEA), BASiX also advances our understanding of these ubiquitous bodies in the small asteroid population. BASiX is an efficient and simple mission concept that can deliver revolutionary science with its threshold mission and adds substantial enhancements with its baseline mission. BASiX assembles an international team of top small body scientists and astronomers and is led by PI Dan Scheeres (University of Colorado). BASiX is managed by JPL, which is also where mission and science operations will be based. The BASiX Spacecraft is built by Ball Aerospace & Technologies Corp. Instruments are built by JPL and Ball with additional contributed instruments from CNES.

Swift Gamma-Ray Burst Explorer: Mission Design for Rapid, Accurate Location of Gamma-ray Bursts

NASA Technical Reports Server (NTRS)

Bundas, David J.

2004-01-01

The Swift Gamma-ray Burst Explorer is a NASA Mid-sized Explorer (MIDEX) with the primary mission of determining the origins of Gamma-Ray Bursts (GRBs). It will be the first mission to autonomously respond to newly-discovered GRBs and provide immediate follow-up narrow field instruments capable of multi-wavelength (UV, Optical, X-ray) observations. The characteristics of GRBs that are the key mission design drivers, are their non-repeating and brief duration bursts of multi-wavelength photons. In addition, rapid notification of the location and characteristics of the GRBs to ground-and-space- based observatories drive the end-to-end data analysis and distribution requirements. The Swift mission is managed by the GSFC, and includes an international team of contributors that each bring their unique perspective that have proven invaluable to the mission. The spacecraft bus, provided by Spectrum Astro, Inc. was procured through a Rapid Spacecraft Development Office (RSDO) contract by the GSFC. There are three instruments: the Burst Alert Telescope (BAT) provided by the GSFC; the X-Ray Telescope (XRT) provided by a team led by the Pennsylvania State University (PSU); and the Ultra-Violet Optical Telescope (UVOT), again managed by PSU. The Mission Operations Center (MOC) was developed by and is located at PSU. Science archiving and data analysis centers are located at the GSFC, in the UK and in Italy.

An Alternative Humans to Mars Approach: Reducing Mission Mass with Multiple Mars Flyby Trajectories and Minimal Capability Investments

NASA Technical Reports Server (NTRS)

Whitley, Ryan J.; Jedrey, Richard; Landau, Damon; Ocampo, Cesar

2015-01-01

Mars flyby trajectories and Earth return trajectories have the potential to enable lower- cost and sustainable human exploration of Mars. Flyby and return trajectories are true minimum energy paths with low to zero post-Earth departure maneuvers. By emplacing the large crew vehicles required for human transit on these paths, the total fuel cost can be reduced. The traditional full-up repeating Earth-Mars-Earth cycler concept requires significant infrastructure, but a Mars only flyby approach minimizes mission mass and maximizes opportunities to build-up missions in a stepwise manner. In this paper multiple strategies for sending a crew of 4 to Mars orbit and back are examined. With pre-emplaced assets in Mars orbit, a transit habitat and a minimally functional Mars taxi, a complete Mars mission can be accomplished in 3 SLS launches and 2 Mars Flyby's, including Orion. While some years are better than others, ample opportunities exist within a given 15-year Earth-Mars alignment cycle. Building up a mission cadence over time, this approach can translate to Mars surface access. Risk reduction, which is always a concern for human missions, is mitigated by the use of flybys with Earth return (some of which are true free returns) capability.

Sentinel-2 mission status

NASA Astrophysics Data System (ADS)

Hoersch, Bianca

2017-04-01

The SENTINEL-2 mission is the European Multispectral Imaging Mission for the Copernicus joint initiative of the European Commission (EC) and the European Space Agency (ESA). The SENTINEL-2 mission includes 13-spectral band multispectral optical imager with different resolution (down to 10 m) and a swath width of 290km. It provides very short revisit times and rapid product delivery. The mission is composed of a constellation of two satellite units, SENTINEL-2A and SENTINEL-2B, sharing the same orbital plane and featuring a short repeat cycle of 5 days at the equator optimized to mitigate the impact of clouds for science and applications. SENTINEL-2 enables exploitation for a variety of land and coastal applications such as agriculture, forestry, land cover and land cover change, urban mapping, emergency, as well as inland water, ice, glaciers and also coastal zone and closed seas applications. Following the launch of the Sentinel-2A in June 2015 and successful operations and data delivery since December 2015, the Sentinel-2B satellite is set for launch in March 2017. The full operation capacity is foreseen after the in-orbit commissioning phase of the Sentinel-2B unit in early summer 2017. The objective of the talk is to provide information about the mission status, and the way to achieve full operational capacity with 2 satellites.

A Manager's Rationale for a Pre-Trauma Developmental Approach to Resilience: A Symbolic Interactionist's Perspective

ERIC Educational Resources Information Center

Walach, Christopher E.

2011-01-01

Imminent danger, managing the unexpected, dealing with the aftereffects of danger and potential trauma, and repeating this intense cycle is part of the military, first responders (police, fire fighters, wild land firefighting crews, EMTs, and paramedics), and emergency management organizations regular mission. Members of these organizations…

Reconfigurable microwave photonic repeater for broadband telecom missions: concepts and technologies

NASA Astrophysics Data System (ADS)

Aveline, M.; Sotom, M.; Barbaste, R.; Benazet, B.; Le Kernec, A.; Magnaval, J.; Ginestet, P.; Navasquillo, O.; Piqueras, M. A.

2017-11-01

Thales Alenia Space has elaborated innovative telecom payload concepts taking benefit from the capabilities of photonics and so-called microwave photonics. The latter consists in transferring RF/microwave signals on optical carriers and performing processing in the optical domain so as to benefit from specific attributes such as wavelength-division multiplexing or switching capabilities.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Graaff, E. de; Willemsen, R.; Zhong, N.

The molecular mechanism of the fragile X syndrome is based on the expansion of an CGG repeat in the 5{prime} UTR of the FMR1 gene in the majority of fragile X patients. This repeat displays instability both between individuals and within an individual. We studied the instability of the CGG repeat and the expression of the FMR1 protein (FMRP) in several different tissues derived from a male fragile X patient. Using Southern blot analysis, only a full mutation is detected in 9 of the 11 tissues tested. The lung tumor contains a methylated premutation of 160 repeats, whereas in themore » testis, besides the full mutation, a premutation of 60 CGG repeats is detected. Immunohistochemistry of the testis revealed expression of FMR1 in the spermatogonia only, confirming the previous finding that, in the sperm cells of fragile X patients with a full mutation in their blood cells, only a premutation is present. Immunohistochemistry of brain and lung tissue revealed that 1% of the cells are expressing the FMRP. PCR analysis demonstrated the presence of a premutation of 160 repeats in these FMR1-expressing cells. This indicates that the tumor was derived from a lung cell containing a premutation. Remarkably, despite the methylation of the EagI and BssHII sites, FMRP expression is detected in the tumor. Methylation of both restriction sites has thus far resulted in a 100% correlation with the lack of FMR1 expression, but the results found in the tumor suggest that the CpGs in these restriction sites are not essential for regulation of FMR1 expression. This indicates a need for a more accurate study of the exact promoter of FMR1. 54 refs., 4 figs.« less

Science Brought by JASMINE Data

NASA Astrophysics Data System (ADS)

Tsujimoto, T.

The planned astrometric space mission JASMINE will provide the exact positions, distances, and proper motions of the bulge stars. These data will certainly reveal the origin and evolution of the Galactic bulge. In fact, the formation process of the bulge is still veiled. It is generally believed that the Galactic bulge possesses a simple old population. On the other hand, the Galactic bulge has a bar with some kinematic implications for a secular evolution. Here we review some evidences for the recent star formation in the Galactic bulge, that will be verified by JASMINE.

STS-113 workers search for oxygen leak

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- In the Payload Changeout Room, Launch Pad 39A, workers raise a platform toward the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

STS-113 workers search for oxygen leak

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- Workers in the Payload Changeout Room, Launch Pad 39A, ride a platform toward the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

STS-113 workers search for oxygen leak

NASA Technical Reports Server (NTRS)

2002-01-01

KENNEDY SPACE CENTER, FLA. -- Workers in the Payload Changeout Room, Launch Pad 39A, are on a platform in the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

KSC-02pd1709

NASA Image and Video Library

2002-11-12

KENNEDY SPACE CENTER, FLA. -- In the Payload Changeout Room, Launch Pad 39A, workers raise a platform toward the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

KSC-02pd1712

NASA Image and Video Library

2002-11-12

KENNEDY SPACE CENTER, FLA. -- Workers in the Payload Changeout Room, Launch Pad 39A, are on a platform in the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

KSC-02pd1710

NASA Image and Video Library

2002-11-12

KENNEDY SPACE CENTER, FLA. -- Workers in the Payload Changeout Room, Launch Pad 39A, ride a platform toward the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

KSC-02pd1711

NASA Image and Video Library

2002-11-12

KENNEDY SPACE CENTER, FLA. -- Workers in the Payload Changeout Room, Launch Pad 39A, are on a platform in the forward cargo bay area of Space Shuttle Endeavour to search for an oxygen leak. The launch of Endeavour on mission STS-113 was postponed Nov. 10, following the completion of tanking operations, due to higher than allowable oxygen levels in the orbiter's midbody. Workers will investigate the exact location and possible cause of the leak, and effect repairs. Launch has been tentatively set for no earlier than Nov. 18, between 7 and 11 p.m. EST.

Predicting Success at Marine Security Guard (MSG) School Utilizing the Headquarters Master File (HMF)

DTIC Science & Technology

1993-03-01

Marines stood watch for varying periods at many of our missions in the years between the World Wars. As a result of this, and expeditions in Asia ...et al. (1978), Wiskoff et al. (1989), and Akst and Quester (1992), in a .tudy of 35 percent of the freshman class at the University of Texas by Fudge...lived through many experiences, and has set as another goal, to become an MSG. He is goal- oriented and knows exactly what he wants to do. The younger

Basic targeting strategies for rendezvous and flyby missions to the near-Earth asteroids

NASA Astrophysics Data System (ADS)

Perozzi, Ettore; Rossi, Alessandro; Valsecchi, Giovanni B.

2001-01-01

Missions to asteroids and comets are becoming increasingly feasible both from a technical and a financial point of view. In particular, those directed towards the Near-Earth Asteroids have proven suitable for a low-cost approach, thus attracting the major space agencies as well as private companies. The choice of a suitable target involves both scientific relevance and mission design considerations, being often a difficult task to accomplish due to the limited energy budget at disposal. The aim of this paper is to provide an approach to basic trajectory design which allows to account for both aspects of the problem, taking into account scientific and technical information. A global characterization of the Near-Earth Asteroids population carried out on the basis of their dynamics, physical properties and flight dynamics considerations, allows to identify a group of candidates which satisfy both, the scientific and engineering requirements. The feasibility of rendezvous and flyby missions towards them is then discussed and the possibility of repeated encounters with the same object is investigated, as an intermediate scenario. Within this framework, the capability of present and near future launch and propulsion systems for interplanetary missions is also addressed.

Parker Solar Probe (PSP): The Dawn of a New Age… 60 Years in the Making

NASA Astrophysics Data System (ADS)

McComas, D. J.

2017-12-01

Next summer the launch window opens July 31, 2018 for the Parker Solar Probe (PSP) mission. This mission will repeatedly fly within 9 solar radii of the Sun's surface and directly measure the particles and fields in the innermost reaches of our heliosphere for the first time. With this historic mission, humanity will be able to achieve the key scientific objectives of 1) tracing the flow of energy that heats and accelerates the solar corona and solar wind, 2) determining the structure and dynamics of the plasma and magnetic fields at the sources of the solar wind, and 3) exploring the mechanisms that accelerate and transport energetic particles near the Sun. Next year also marks the 60th anniversary of the 1958 report from the Physics of Particles and Fields in Space Committee of the National Research Council's Space Studies Board, chaired by John Simpson and James Van Allen, which first called for sending a spacecraft to measure the particles and fields environment near the Sun. This talk briefly reviews the history, examines how we got to the current PSP mission, and describes some of the science drivers and the promise of what the PSP mission is about to accomplish.

Age-related change in the association between a polymorphism in the PER3 gene and preferred timing of sleep and waking activities.

PubMed

Jones, Kay H S; Ellis, Jason; von Schantz, Malcolm; Skene, Debra J; Dijk, Derk-Jan; Archer, Simon N

2007-03-01

The objective of this study was to investigate the effect of age on the association between preferred timing of sleep and waking activities and a coding-region variable number tandem repeat (VNTR) polymorphism in the clock gene PER3. We have previously reported this polymorphism to associate with diurnal preference and delayed sleep phase syndrome (DSPS). Participants (n = 1590; 707 males and 883 females) completed the Horne-Ostberg (HO) questionnaire for diurnal preference and provided a DNA sample. Overall HO scores were plotted against age. The 5% extremes and intermediates were selected for genotyping. Frequencies of the PER3 4- and 5-repeat alleles were examined in separate age groups (18-29, 30-39, 40-49 and 50+ years of age). The 4-repeat allele was significantly more frequent in evening types, and the 5-repeat allele more frequent in morning types (Fisher's exact test, P = 0.016). Analysis in the four age groupings revealed that the strength of this association attenuated with age and was significant only in the youngest group (18-29 years). These results extend our previous finding of an association between the PER3 VNTR and diurnal preference. They also demonstrate that diurnal preference in young people is more closely associated with this polymorphism than it is in other age groups.

Visual consciousness and intertrial feature priming.

PubMed

Peremen, Ziv; Hilo, Rinat; Lamy, Dominique

2013-04-01

Intertrial repetition priming plays a striking role in visual search. For instance, when searching for a target with a unique color, performance is substantially better when the specific color of the target repeats on successive trials (Maljkovic & Nakayama, 1994). Recent research has relied on objective measures of performance to show that priming improves the perceptual quality of the repeated target. Here, we examined the relation between priming and conscious perception of the target by adding a subjective measure of perception. We used backward masking to create liminal perception, that is, different levels of subjectively conscious perception of the target using exactly the same stimulus conditions. The displays in either probe trials (in which priming benefits are measured, experiment 1) or in prime trials (in which memory traces are laid down, experiment 2) were masked. The results showed that intertrial priming improves full access to awareness of the repeated target but only for targets that already achieved partial access to awareness. In addition, they show that full awareness of the target is necessary in both the prime and probe trials for intertrial priming effects to emerge. Implications for the role of implicit short-term memory in visual search are discussed.

Iterative dictionary construction for compression of large DNA data sets.

PubMed

Kuruppu, Shanika; Beresford-Smith, Bryan; Conway, Thomas; Zobel, Justin

2012-01-01

Genomic repositories increasingly include individual as well as reference sequences, which tend to share long identical and near-identical strings of nucleotides. However, the sequential processing used by most compression algorithms, and the volumes of data involved, mean that these long-range repetitions are not detected. An order-insensitive, disk-based dictionary construction method can detect this repeated content and use it to compress collections of sequences. We explore a dictionary construction method that improves repeat identification in large DNA data sets. Our adaptation, COMRAD, of an existing disk-based method identifies exact repeated content in collections of sequences with similarities within and across the set of input sequences. COMRAD compresses the data over multiple passes, which is an expensive process, but allows COMRAD to compress large data sets within reasonable time and space. COMRAD allows for random access to individual sequences and subsequences without decompressing the whole data set. COMRAD has no competitor in terms of the size of data sets that it can compress (extending to many hundreds of gigabytes) and, even for smaller data sets, the results are competitive compared to alternatives; as an example, 39 S. cerevisiae genomes compressed to 0.25 bits per base.

Evaluation of repeated exposure systemic toxicity test of PVC with new plasticizer on rats via dual parenteral routes

PubMed Central

Hou, Li; Fan, Chunguang; Liu, Chenghu; Qu, Qiujin; Wang, Chunren

2018-01-01

Abstract Systemic toxicity caused by repeated exposure to both polar and nonpolar leachables of di(2-ethylhexyl)-1,2-cyclohexane plasticized polyvinyl chloride (PVC) was evaluated with dual routes of parenteral administration method on rats in the study. Experimental group and control group were designed by researchers. Tail intravenous injection with 0.9% sodium chloride injection extracts and intraperitoneal injection with corn oil extracts were conducted to the experimental rats while tail intravenous injection with 0.9% sodium chloride Injection and intraperitoneal injection with corn oil were conducted to the control rats. After 14 days, blood specimens were collected for clinical pathology (hematology and clinical chemistry) analysis. Selected organs were weighed and a histopathological examination was conducted. As a result, compared with the control animals, there were no toxicity-related changes on the parameters above. The results show that the rats do not show obvious systemic toxicity reaction caused by repeated exposure with dual routes of parenteral administration method on rats after administration with both polar and nonpolar exacts of di(2-ethylhexyl)-1,2-cyclohexane plasticized PVC simultaneously up for 14 days. PMID:29423263

The effect of image alignment on capillary blood flow measurement of the neuroretinal rim using the Heidelberg retina flowmeter

PubMed Central

Sehi, M; Flanagan, J G

2004-01-01

Aim: To examine the influence of image alignment on the repeatability of blood flow measurements of the optic nerve. Methods: 10 normal subjects were examined. Heidelberg retina tomograph imaging was performed to establish best location and focus for the temporal neuroretinal rim. Two high quality Heidelberg retina flowmeter (HRF) images were acquired for three methods of alignment: central, nasal, and temporal. A 10×10 pixel measurement window was selected and exactly reproduced on all images. The interquartile pixel values were used to calculate capillary flow. ANOVA, intraclass correlation coefficients (ICC) and the coefficient of repeatability (CoR) were used for analysis. Results: There was no difference between methods (p = 0.47) or between visits (p = 0.51). The ICCs were 0.83 for the central, 0.34 for the nasal, and 0.42 for the temporal alignment. The CoR was 31.5 for central (mean effect 235.1), 234.6 for nasal, and 256.7 for temporal alignment. Conclusion: Central alignment was the most repeatable method for the measurement of neuroretinal rim capillary blood flow using the HRF. PMID:14736775

[The accuracy of palpation from orientation points for the navigated implantation of knee prostheses].

PubMed

Fuiko, R; Kotten, B; Zettl, R; Ritschl, P

2004-03-01

Cinematic and pointing procedures are used for non-image based navigated implantation during total knee replacement. Pointing procedures require an exact knowledge of the landmarks. In this anatomical study, landmarks are defined and repeatedly referenced. Precision and reproducibility are evaluated by means of an inter- and an intra-observer study. The axes of the femur and tibia are calculated using the landmarks. The specific landmarks of 30 femurs and 27 tibias were palpated by three surgeons and digitised by means of a photogrammetric system, as used intra-operatively. The recorded data were statistically evaluated. The specific landmarks can be referenced with great precision. The vectors that influence the implant position show a mean femoral deviation of 0.9 mm and a mean tibial deviation of 1.0 mm. The repeating accuracy of every observer was 1.5 mm femoral and 1.0 mm tibial. The calculated long axes at the femur and tibia thus reach a precision of 0.1 degrees (min.-max.: 0-0.9 degrees) at the femur and 0.2 degrees (.0-1.1 degrees) at the tibia. The short axes at the distal femur and proximal tibia exhibit an average deviation of from 0.7 degrees to 1.9 degrees (0-11.3 degrees). Long axes (mechanical axes) can be determined exactly but the precision of the short axes (rotational axes) is unsatisfactory, although palpation of landmarks was accurate. Therefore, palpation of more than one rotational axis at the femur and tibia is mandatory and should be visualized on the monitor during surgery.

Lunar Outpost Life Support Trade Studies

NASA Technical Reports Server (NTRS)

Lange, Kevin E.; Anderson, Molly S.; Ewert, Michael K.; Barta, Daniel J.

2008-01-01

Engineering trade-off studies of life support system architecture and technology options were conducted for potential lunar surface mission scenarios within NASA's Constellation Program. The scenarios investigated are based largely on results of the NASA Lunar Architecture Team (LAT) Phase II study. In particular, the possibility of Hosted Sortie missions, the high cost of power during eclipse periods, and the potential to reduce life support consumables through scavenging, in-situ resources, and alternative EVA technologies were all examined. These trade studies were performed within the Systems Integration, Modeling and Analysis (SIMA) element of NASA's Exploration Life Support (ELS) technology development project. The tools and methodology used in the study are described briefly, followed by a discussion of mission scenarios, life support technology options and results presented in terms of equivalent system mass for various regenerative life support technologies and architectures. Three classes of repeated or extended lunar surface missions were investigated in this study along with several life support resource scenarios for each mission class. Individual mission durations of 14 days, 90 days and 180 days were considered with 10 missions assumed for each at a rate of 2 missions per year. The 14-day missions represent a class of Hosted Sortie missions where a pre-deployed and potentially mobile habitat provides life support for multiple crews at one or more locations. The 90-day and 180-day missions represent lunar outpost expeditions with a larger fixed habitat. The 180-day missions assume continuous human presence and must provide life support through eclipse periods of up to 122 hours while the 90-day missions are planned for best-case periods of nearly continuous sunlight. This paper investigates system optimization within the assumptions of each scenario and addresses how the scenario selected drives the life support system to different designs. Subsequently, these analysis results can be used to determine which technologies may be good choices throughout a broad range of architectures.

KIC 8462852 Brightness Pattern Repeating Every 1600 days

NASA Astrophysics Data System (ADS)

Gary, Bruce; Bourne, Rafik

2017-12-01

Observations of KIC 8462852 (aka Boyajian's Star) reveal a yearlong fade pattern that is remarkably similar to the fade pattern derived from Kepler mission observations. The ground-based observations reported here can be described as a gradual fade that ended in late 2016 with the beginning of a yearlong U-shaped fade of 1.1 percent. Near the end of this U-shaped fade a series of very brief dips occurred. The Kepler data exhibit a similar pattern 1600 days earlier, except with an abrupt end of observations before the U-shape recovery. Observations lasting many years are needed, especially during our predicted repeat of the U-shape and short dip pattern in 2021.

Testing the Deployment Repeatability of a Precision Deployable Boom Prototype for the Proposed SWOT Karin Instrument

NASA Technical Reports Server (NTRS)

Agnes, Gregory S.; Waldman, Jeff; Hughes, Richard; Peterson, Lee D.

2015-01-01

NASA's proposed Surface Water Ocean Topography (SWOT) mission, scheduled to launch in 2020, would provide critical information about Earth's oceans, ocean circulation, fresh water storage, and river discharge. The mission concept calls for a dual-antenna Ka-band radar interferometer instrument, known as KaRIn, that would map the height of water globally along two 50 km wide swaths. The KaRIn antennas, which would be separated by 10 meters on either side of the spacecraft, would need to be precisely deployable in order to meet demanding pointing requirements. Consequently, an effort was undertaken to design build and prototype a precision deployable Mast for the KaRIn instrument. Each mast was 4.5-m long with a required dilitation stability of 2.5 microns over 3 minutes. It required a minimum first mode of 7 Hz. Deployment repeatability was less than +/- 7 arcsec in all three rotation directions. Overall mass could not exceed 41.5 Kg including any actuators and thermal blanketing. This set of requirements meant the boom had to be three times lighter and two orders of magnitude more precise than the existing state of the art for deployable booms.

The Ares 3 Landing Site: Where Science Fact Meets Fiction

NASA Image and Video Library

2015-10-05

This image from the High Resolution Imaging Science Experiment (HiRISE) camera on NASA's Mars Reconnaissance Orbiter shows a location on Mars associated with the best-selling novel and Hollywood movie, "The Martian." This area is in the Acidalia Planitia region. In the novel and the movie, it is the landing site of a crewed mission named Ares 3. For the story's central character, Acidalia Planitia is within driving distance from where NASA's Mars Pathfinder, with its Sojourner rover, landed in 1997. An initial HiRISE image of the site was taken in April 2015 and is online at http://hirise.lpl.arizona.edu/ESP_040776_2115. A second one was taken May 17, 2015, and is shown here. Figure 1 is a stereo combination of the two, appearing three-dimensional when viewed through blue-red glasses with the red lens on the left One of the main objectives of the HiRISE camera is to carry out "monitoring science", which involves taking images of certain areas of high scientific interest on regular intervals. The team usually does so to monitor a seasonal or recurring process such as seasonal changes in carbon-dioxide ice near the poles, dune movement or recurring flow-like features on some slopes. HiRISE also takes repeated images of areas with active rovers, such as Curiosity, to help plan safe routes toward areas of high scientific interest. Another key responsibility for the HiRISE camera is to provide information for use in selection of landing sites for future missions. One technique is to image a site of interest at least twice when the weather conditions are similar, but with a small difference in viewing angle, much like what you would experience if you looked at something with only your right eye, then looked at it again with the left. By doing this, we are able to build a stereo view of the site, providing a chance to identify high and low points in the site more effectively. This resulting 3-D information can combined with elevation data from laser altimeters to create a highly accurate "digital terrain model" or DTM for short. DTMs allow researchers to view the locations in 3-D and to analyze them by measuring the exact height of features that could be hazardous to the future mission, such as large boulders or small impact craters. DTMs from HiRISE were a key factor in choosing the landing site for NASA's Curiosity Mars rover in Gale Crater and are being used to evaluate sites under consideration for the NASA's 2016 InSight Mars lander and Mars 2020 rover missions. The location of the site in this image is 31.3 degrees north latitude, 331.3 degrees east latitude. The image is an excerpt from HiRISE observation ESP_041277_2115. http://photojournal.jpl.nasa.gov/catalog/PIA19913

Collection, quality control and delivery of ground-based magnetic data during ESA's Swarm mission

NASA Astrophysics Data System (ADS)

Macmillan, Susan; Humphries, Thomas; Flower, Simon; Swan, Anthony

2016-04-01

Ground-based magnetic data are used in a variety of ways when analysing satellite data. Selecting satellite data often involves the use of magnetic disturbance indices derived from ground-based stations and inverting satellite magnetic data for models of fields from various sources often requires ground-based data. Ground-based data can also be valuable independent data for validation purposes. We summarise data collection and quality control procedures in place at the British Geological Survey for global ground-based observatory and repeat station data. Whilst ongoing participation in the ICSU World Data System and INTERMAGNET facilitates this work, additional procedures have been specially developed for the Swarm mission. We describe these in detail.

NIMS: hotspots on Io during G2 (continued)

NASA Technical Reports Server (NTRS)

1997-01-01

This is another Near Infrared Mapping Spectrometer (NIMS) image of Io, taken during the G2 encounter in September 1996. This is a dayside image of Io (on the right) against the clouds of Jupiter (the blue background). On the left is a Voyager mosaic of Io with the same viewing geometry for comparison purposes. This NIMS data set has been processed to highlight the positions of hot spots on the surface of Io. At least 11 can be seen. Two of the hotspots are newly discovered by the NIMS instrument. Others correspond to sites of plume eruptions and volcanic calderas and volcanic flows. This image can be compared with the SSI image P-47971 released on October 23, 1996, which was taken almost exactly the same position.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.

This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

Hubble Sees a Young Star Take Center Stage

NASA Image and Video Library

2015-03-06

With its helical appearance resembling a snail’s shell, this reflection nebula seems to spiral out from a luminous central star in this NASA/ESA Hubble Space Telescope image. The star in the center, known as V1331 Cyg and located in the dark cloud LDN 981 — or, more commonly, Lynds 981 — had previously been defined as a T Tauri star. A T Tauri is a young star — or Young Stellar Object — that is starting to contract to become a main sequence star similar to the sun. What makes V1331Cyg special is the fact that we look almost exactly at one of its poles. Usually, the view of a young star is obscured by the dust from the circumstellar disc and the envelope that surround it. However, with V1331Cyg we are actually looking in the exact direction of a jet driven by the star that is clearing the dust and giving us this magnificent view. This view provides an almost undisturbed view of the star and its immediate surroundings allowing astronomers to study it in greater detail and look for features that might suggest the formation of a very low-mass object in the outer circumstellar disk. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

An Investigation into Establishing a Formation of Small Satellites in a Lunar Flower Constellation

NASA Astrophysics Data System (ADS)

McManus, Lauren

Lunar science missions such as LADEE and GRAIL achieved unprecedented measurements of the Lunar exosphere and gravity field. These missions were performed with one (LADEE) or two (GRAIL) traditional satellites. The global coverage achieved by these missions could have been greatly enhanced with the use of a constellation of satellites. A constellation of communication satellites at the Moon would also be necessary if a Lunar human base were to be established. Constellations with many satellites are expensive with traditional technology, but have become feasible through the technological advancements and affordability of cubesats. Cubesat constellations allow for full surface coverage in science or communication missions at a reasonable mission cost. Repeat ground track orbits offer interesting options for science or communication constellations, since they provide repeat coverage of the surface at a fixed time between sequential visits. Flower constellations are a family of constellations being studied primarily by Daniele Mortari at Texas A&M; University that make use of repeat ground tracks. Orbital parameters are selected such that the nodal period of the orbit matches the nodal period of the primary body by a factor dependent on the number of days and the number of revolutions to repeat the ground track. All orbits in a flower constellation have identical orbital elements, with the exception of the right ascension of the ascending node (RAAN) and the initial mean anomaly, which are determined based on the desired phasing scheme desired. Flower constellations have thus far primarily been studied at Earth. A flower constellation at the Moon could be quite useful for science or communication purposes. In this scenario, the flower constellation satellites would be small satellites, which introduces many unique challenges. The cubesats would have limited propulsion capability and would need to be deployed from a mothercraft. Orbital maintenance would then be required after deployment to retain the repeat ground track nature of flower constellations. The limited fuel on the cubesats and the maneuvers required determine the lifetime of the constellation. The communications range of the cubesats will also be limited; following a successful deployment, the mothercraft must move into a long-term communications orbit where it can see both the children craft and Earth, to act as a communications relay. This work investigates the differences in flower constellations at the Moon versus at Earth. It is found that due to the longer rotation period of the Moon, the number of petals in the flower constellation must be quite large in order to produce reasonable orbit sizes. Two types of flower constellations are investigated: a single-petal and multi-petal constellation. The single-petal constellation consists of a string-of-pearls formation within one inertial flower constellation orbit. The multi-petal configuration has one satellite per inertial orbit, with the orbits spaced symmetrically within a 360 degree RAAN distribution. Optimal methods for deployment are explored for both configurations. Phasing orbits are used to deploy the single-petal constellation. This is found to be a simple and low-cost deployment scheme. The multi-petal configuration requires larger plane change maneuvers, and three-burn transfer orbit solutions that are optimal over single impulsive burn maneuvers are found. The mothercraft maneuver into the long-term communications orbit is also investigated. This maneuver is once again just a phase orbit maneuver for the single-petal constellation and is low cost. A polar mothercraft orbit is desired for the multi-petal configuration, again requiring a large and expensive plane change maneuver. As was the case with the deployment maneuver, a three-burn transfer orbit series is found to be cost optimal over a series of impulsive burns for this maneuver. Finally, once the constellation is established, orbit maintenance maneuvers are calculated. A 4 kg cubesat with 1 kg of fuel is assumed, and various thruster types are used to correlate required maintenance Delta-Vs to propellant mass required. It is found that the flower constellations at the Moon can be maintained for between 100 and 800 days, depending on the eciency of the thruster system used. Ultimately, a small satellite constellation at the Moon is found to be feasible to establish and maintain for a science or communication mission.

Compendium of Information for Interpreting the Microgravity Environment of the Orbiter Spacecraft

NASA Technical Reports Server (NTRS)

DeLombard, Richard

1996-01-01

Science experiments are routinely conducted on the NASA shuttle orbiter vehicles. Primarily, these experiments are operated on such missions to take advantage of the microgravity (low-level acceleration) environment conditions during on-orbit operations. Supporting accelerometer instruments are operated with the experiments to measure the microgravity acceleration environment in which the science experiments were operated. Tne Principal Investigator Microgravity Services (PIMS) Project at NASA Lewis Research Center interprets these microgravity acceleration data and prepares mission summary reports to aid the principal investigators of the scientific experiments in understanding the microgravity environment. Much of the information about the orbiter vehicle and the microgravity environment remains the same for each mission. Rather than repeat that information in each mission summary report, reference information is presented in this report to assist users in understanding the microgravity-acceleration data. The characteristics of the microgravity acceleration environment are first presented. The methods of measurement and common instruments used on orbiter missions are described. The coordinate systems utilized in the orbiter and accelerometers are described. Some of the orbiter attitudes utilized in microgravity related missions are illustrated. Methods of data processing are described and illustrated. The interpretation of the microgravity acceleration data is included with an explanation of common disturbance sources. Instructions to access some of the acceleration data and a description of the orbiter thrusters are explained in the appendixes. A microgravity environment bibliography is also included.

Self-repeating properties of four-petal Gaussian vortex beams in quadratic index medium

NASA Astrophysics Data System (ADS)

Zou, Defeng; Li, Xiaohui; Chai, Tong; Zheng, Hairong

2018-05-01

In this paper, we investigate the propagation properties of four-petal Gaussian vortex (FPGV) beams propagating through the quadratic index medium, obtaining the analytical expression of FPGV beams. The effects of beam order n, topological charge m and beam waist ω0 are investigated. Results show that quadratic index medium support periodic distributions of FPGV beams. A hollow optical wall or an optical central principal maximum surrounded by symmetrical sidelobes will occur at the center of a period. At length, they will evolve into four petals structure, exactly same as the intensity distributions at source plane.

The Prototype HyspIRI Thermal Infrared Radiometer (PHyTIR): A High Speed, Multispectral, Thermal Instrument Development in Support of HyspIRI-TIR

NASA Technical Reports Server (NTRS)

Hook, Simon

2011-01-01

The Prototype HyspIRI Thermal Infrared Radiometer (PHyTIR) is being developed as part of the risk reduction activities associated with the Hyperspectral Infrared Imager (HyspIRI). The HyspIRI mission was recommended by the National Research Council Decadal Survey and includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. The HyspIRI TIR system will have 60m ground resolution, better than 200mK noise equivalent delta temperature (NEDT), 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. PHyTIR addresses the technology readiness level (TRL) of certain key subsystems of the TIR imager, primarily the detector assembly and scanning mechanism. PHyTIR will use Mercury Cadmium Telluride (MCT) technology at the focal plane and operate in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence allowing the high data rates needed for the 5 day repeat. PHyTIR will also demonstrate a newly developed interferometeric metrology system. This system will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing post-processing (e.g. geo-rectification computations).

Calibration of the Neutral Mass Spectrometer for the Lunar Atmosphere and Dust Environment Explorer

NASA Technical Reports Server (NTRS)

Mahaffy, P. R.; Hodges, R. R.; Harpold, D. N.; King, T. T.; Jaeger, F.; Raaen, E.; Lyness, E.; Collier, M.; Benna, M.

2012-01-01

Science objectives of the LADEE Mission are to (1) determine the composition, and time variability of the tenuous lunar atmosphere and (2) to characterize the dust environment and its variability. These studies will extend the in-situ characterization of the environment that were carried out decades ago with the Apollo missions and a variety of ground based studies. The focused LADEE measurements will enable a more complete understanding of dust and gas sources and sinks. Sources of gas include UV photo-stimulated desorption, sputtering by plasma and micrometeorites, as well as thermal release of species such as argon from the cold service or venting from the lunar interior. Sinks include recondensation on the surface and escape through a variety of mechanisms. The LADEE science payload consists of an Ultraviolet Spectrometer, a Neutral Mass Spectrometer, and a Dust Detector. The LADEE orbit will include multiple passes at or below 50 km altitude and will target repeated sampling at the sunrise terminator where exospheric density will be highest for some thermally released species. The science mission will be implemented in approximately three months to allow measurements to be made over a period of one or more lunations In addition to the science mission NASA will use this mission to demonstrate optical communication technology away from low Earth orbit.

Unmanned Aircraft Systems Roadmap, 2005-2030

DTIC Science & Technology

2005-01-01

directly addresses the dangerous mission of attacking or degrading integrated air defense systems. The attributes that make the use of unmanned...meter of reinforced concrete covered by one meter of soil . The Air Force hopes to deploy it by 2007 on the F-15E, followed by deployment on several... degradation from repeated analog-digital-analog conversions. For this reason, multispectral versions of digital focal arrays are critical. Additionally

Dramatic and long-term lake level changes in the Qinghai-Tibet Plateau from Cryosat-2 altimeter: validation and augmentation by results from repeat altimeter missions and satellite imagery

NASA Astrophysics Data System (ADS)

Hwang, Cheinway; Huang, YongRuei; Cheng, Ys; Shen, WenBin; Pan, Yuanjin

2017-04-01

The mean elevation of the Qinghai-Tibet Plateau (QTP) exceeds 4000 m. Lake levels in the QTP are less affected by human activities than elsewhere, and may better reflect the state of contemporary climate change. Here ground-based lake level measurements are rare. Repeat altimeter missions, particularly those from the TOPEX and ERS series of altimetry, have provided long-term lake level observations in the QTP, but their large cross-track distances allow only few lakes to be monitored. In contrast, the Cryosat-2 altimeter, equipped with the new sensor SIRAL (interferometric/ synthetic aperture radar altimeter), provides a much better ranging accuracy and a finer spatial coverage than these repeated missions, and can detect water level changes over a large number of lakes in the QTP. In this study, Cryosat-2 data are used to determine lake level changes over 75˚E-100˚E and 28˚N-37.5˚N, where Cryosat-2 covers 60 lakes and SARAL/ AltiKa covers 32 lakes from 2013 to 2016. Over a lake, Cryosat-2 in different cycles can pass through different spots of the lake, making the numbers of observations non-uniform and requiring corrections for lake slopes. Four cases are investigated to cope with these situations: (1) neglecting inconsistency in data volume and lake slopes (2) considering data volume, (3) considering lake slopes only, and (4) considering both data volume and lake slopes. The CRYOSAT-2 result is then compared with the result from the SARAL to determine the best case. Because Cryosat-2 is available from 2010 to 2016, Jason-2 data are used to fill gaps between the time series of Cryosat-2 and ICESat (2003-2009) to obtain >10 years of lake level series. The Cryosat-2 result shows dramatic lake level rises in Lakes Kusai, Zhuoaihu and Salt in 2011 caused by floods. Landsat satellite imagery assists the determination and interpretation of such rises.

Evaluation of Landscape Structure Using AVIRIS Quicklooks and Ancillary Data

NASA Technical Reports Server (NTRS)

Sanderson, Eric W.; Ustin, Susan L.

1998-01-01

Currently the best tool for examining landscape structure is remote sensing, because remotely sensed data provide complete and repeatable coverage over landscapes in many climatic regimes. Many sensors, with a variety of spatial scales and temporal repeat cycles, are available. The Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) has imaged over 4000 scenes from over 100 different sites throughout North America. For each of these scenes, one-band "quicklook" images have been produced for review by AVIRIS investigators. These quicklooks are free, publicly available over the Internet, and provide the most complete set of landscape structure data yet produced. This paper describes the methodologies used to evaluate the landscape structure of quicklooks and generate corresponding datasets for climate, topography and land use. A brief discussion of preliminary results is included at the end. Since quicklooks correspond exactly to their parent AVIRIS scenes, the methods used to derive climate, topography and land use data should be applicable to any AVIRIS analysis.

The compulsion to repeat relationships with abusive partners and how group therapy can help.

PubMed

Nicholas, Mary W

2013-07-01

The mystery of why some people are compelled to repeatedly engage in relationships with people who are cruel to them is frequently pondered in literature and psychology. The present paper posits that the etiology of this pathological relationship pattern derives from a parental relationship that was both highly exciting and highly frustrating. Spontaneous recapitulations of the passionate masochistic relationship in the therapy group allow the patient, the therapist and the group to appreciate the exact nature of the "bad" partner's appeal for the patient and its link to parental antecedents. In addition, the author suggests, group therapy can provide attachment experiences that are stimulating and rewarding enough to override the patient's attraction to the toxic partner(s) and build an enhanced capacity for intimacy. The cases of two patients are presented who spent three and a half years in the same long term psychodynamic group, and who, through the processes described above, successfully resolved their masochistic relationship patterns.

Group B Streptococcal Serine-Rich Repeat Proteins Promote Interaction With Fibrinogen and Vaginal Colonization

PubMed Central

Wang, Nai-Yu; Patras, Kathryn A.; Seo, Ho Seong; Cavaco, Courtney K.; Rösler, Berenice; Neely, Melody N.; Sullam, Paul M.; Doran, Kelly S.

2014-01-01

Group B streptococcus (GBS) can cause severe disease in susceptible hosts, including newborns, pregnant women, and the elderly. GBS serine-rich repeat (Srr) surface glycoproteins are important adhesins/invasins in multiple host tissues, including the vagina. However, exact molecular mechanisms contributing to their importance in colonization are unknown. We have recently determined that Srr proteins contain a fibrinogen-binding region (BR) and hypothesize that Srr-mediated fibrinogen binding may contribute to GBS cervicovaginal colonization. In this study, we observed that fibrinogen enhanced wild-type GBS attachment to cervical and vaginal epithelium, and that this was dependent on Srr1. Moreover, purified Srr1-BR peptide bound directly to host cells, and peptide administration in vivo reduced GBS recovery from the vaginal tract. Furthermore, a GBS mutant strain lacking only the Srr1 “latching” domain exhibited decreased adherence in vitro and decreased persistence in a mouse model of GBS vaginal colonization, suggesting the importance of Srr–fibrinogen interactions in the female reproductive tract. PMID:24620021

Technicians complete foaming around Atlantis', OV-104, 17" ET feed line

NASA Image and Video Library

1990-07-10

Technicians complete foaming around the area of Atlantis, Orbiter Vehicle (OV) 104, 17 inch diameter external tank (ET) feed line in preparation for the second liquid hydrogen tanking test at the Kennedy Space Center (KSC). An elaborate network of sensors, leak detectors, and baggies were set up on OV-104 by technicians. Engineers hope this extra instrumentation will help pinpoint the exact location of the leak. OV-104 is scheduled to be launched for the STS-38 mission, a classified Department of Defense (DOD) flight. View provided by KSC with alternate number KSC-90PC-988.

Deploying Object Oriented Data Technology to the Planetary Data System

NASA Technical Reports Server (NTRS)

Kelly, S.; Crichton, D.; Hughes, J. S.

2003-01-01

How do you provide more than 350 scientists and researchers access to data from every instrument in Odyssey when the data is curated across half a dozen institutions and in different formats and is too big to mail on a CD-ROM anymore? The Planetary Data System (PDS) faced this exact question. The solution was to use a metadata-based middleware framework developed by the Object Oriented Data Technology task at NASA s Jet Propulsion Laboratory. Using OODT, PDS provided - for the first time ever - data from all mission instruments through a single system immediately upon data delivery.

Technicians complete foaming around Atlantis', OV-104, 17' ET feed line

NASA Technical Reports Server (NTRS)

1990-01-01

Technicians complete foaming around the area of Atlantis, Orbiter Vehicle (OV) 104, 17 inch diameter external tank (ET) feed line in preparation for the second liquid hydrogen tanking test at the Kennedy Space Center (KSC). An elaborate network of sensors, leak detectors, and baggies were set up on OV-104 by technicians. Engineers hope this extra instrumentation will help pinpoint the exact location of the leak. OV-104 is scheduled to be launched for the STS-38 mission, a classified Department of Defense (DOD) flight. View provided by KSC with alternate number KSC-90PC-988.

Highly efficient, very low-thrust transfer to geosynchronous orbit - Exact and approximate solutions

NASA Astrophysics Data System (ADS)

Redding, D. C.

1984-04-01

An overview is provided of the preflight, postflight, and accuracy analysis of the Titan IIIC launch vehicle that injects payloads into geosynchronous orbits. The postflight trajectory reconstruction plays an important role in determining payload injection accuracy. Furthermore, the postflight analysis provides useful information about the characteristics of measuring instruments subjected to a flight environment. Suitable approaches for meeting mission specifications, trajectory requirements, and instrument constraints are considered, taking into account the importance of preflight trajectory analysis activities. Gimbal flip avoidance algorithms in the flight software, and considerable beta gimbal analysis ensures a singularity-free trajectory.

Development of electrochemical super capacitors for EMA applications

NASA Technical Reports Server (NTRS)

Kosek, J. A.; Dunning, T.; Laconti, A. B.

1995-01-01

In a NASA SBIR Phase I program (Contract No. NAS8-40119), Giner, Inc. evaluated the feasibility of fabricating an all-solid-ionomer multicell electrochemical capacitor having a unit cell capacitance greater than 2 F/sq cm and a repeating element thickness of 6 mils. This capacitor can possibly be used by NASA as a high-rate energy source for electromechanical actuator (EMA) activation for advanced space missions. The high unit cell capacitance and low repeating element thickness will allow for the fabrication of a low-volume, low-weight device, favorable characteristics for space applications. These same characteristics also make the capacitor attractive for terrestrial applications, such as load-leveling batteries or fuel cells in electric vehicle applications. Although the projected energy densities for electrochemical capacitors are about two orders of magnitude lower than that of batteries, the high-power-density characteristics of these devices render them as potentially viable candidates for meeting pulse or peak electrical power requirements for some anticipated aerospace mission scenarios, especially those with discharge times on the millisecond to second time scale. On a volumetric or gravimetric basis, the advantages of utilizing electrochemical capacitors rather than batteries for meeting the peak power demands associated with a specific mission scenario will largely depend upon the total and pulse durations of the power peaks. The effect of preparation conditions on RuO(x), the active component in an all-solid-ionomer electrochemical capacitor, was evaluated during this program. Methods were identified to prepare RuO(x) having a surface areagreater than 180 sq m/g, and a capacitance of greater than 2 F/sq cm. Further efforts to reproducibly obtain these high-surface-area materials in scaled-up batches will be evaluated in Phase 2. During this Phase 1 program we identified a superior Nafion 105 membrane, having a film thickness of 5 mils, that showed excellent performance in our all-solid-ionomer capacitors and resulted in electrochemical capacitors with a repeating element thickness of 8 mils. We are currently working with membrane manufacturers to obtain a high performance membrane in less than 3 mil thickness to obtain a repeating element thickness of 6 mils or less. A 10-cell all-solid ionomer capacitor stack, with each cell having a 222 sq cm active area, was fabricated and evaluated as part of the Phase 1 program. Further Scale-up of a high-energy-density stack is plannedin Phase 2.

Development and validation of an ultra performance liquid chromatography Q-Exactive Orbitrap mass spectrometry for the determination of fipronil and its metabolites in tea and chrysanthemum.

PubMed

Chen, Hongping; Gao, Guanwei; Liu, Pingxiang; Pan, Meiling; Chai, Yunfeng; Liu, Xin; Lu, Chengyin

2018-04-25

A fast, sensitive and reliable method for the determination of fipronil and its metabolites in tea and chrysanthemum was developed using a modified QuEChERS technique and an ultra performance liquid chromatography Q-Exactive Orbitrap mass spectrometry. The mixture of adsorbents containing primary secondary amine (PSA), octadecylsilane (C 18 ) and carbon nanotubes (CNTs), was used as QuEChERS adsorbents. The use of mass resolution at 70000 full width at half maximum (FWHM) and narrow mass windows at 5 ppm achieved high selectivity and repeatability. Satisfactory linearity with correlative coefficient (R 2 ) higher than 0.996 was achieved for all compounds. Recoveries at three levels (2, 10 and 50 μg kg -1 ) ranged from 86% to 112%, while the intra- and inter-day accuracies were less than 15%. Limits of quantification for fipronil and its metabolites were 2 μg kg -1 , which fulfils the requirement of maximum residue limits formulated by European Union and Japan. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Mathematical Motivation for Complex-Valued Convolutional Networks.

PubMed

Tygert, Mark; Bruna, Joan; Chintala, Soumith; LeCun, Yann; Piantino, Serkan; Szlam, Arthur

2016-05-01

A complex-valued convolutional network (convnet) implements the repeated application of the following composition of three operations, recursively applying the composition to an input vector of nonnegative real numbers: (1) convolution with complex-valued vectors, followed by (2) taking the absolute value of every entry of the resulting vectors, followed by (3) local averaging. For processing real-valued random vectors, complex-valued convnets can be viewed as data-driven multiscale windowed power spectra, data-driven multiscale windowed absolute spectra, data-driven multiwavelet absolute values, or (in their most general configuration) data-driven nonlinear multiwavelet packets. Indeed, complex-valued convnets can calculate multiscale windowed spectra when the convnet filters are windowed complex-valued exponentials. Standard real-valued convnets, using rectified linear units (ReLUs), sigmoidal (e.g., logistic or tanh) nonlinearities, or max pooling, for example, do not obviously exhibit the same exact correspondence with data-driven wavelets (whereas for complex-valued convnets, the correspondence is much more than just a vague analogy). Courtesy of the exact correspondence, the remarkably rich and rigorous body of mathematical analysis for wavelets applies directly to (complex-valued) convnets.

A Predominant Variable-Number Tandem-Repeat Cluster of Mycobacterium tuberculosis Isolates among Asylum Seekers in the Netherlands and Denmark, Deciphered by Whole-Genome Sequencing

PubMed Central

de Neeling, Albert; Rasmussen, Erik Michael; Norman, Anders; Mulder, Arnout; van Hunen, Rianne; de Vries, Gerard; Haddad, Walid; Anthony, Richard; Lillebaek, Troels; van der Hoek, Wim; van Soolingen, Dick

2017-01-01

ABSTRACT In many countries, Mycobacterium tuberculosis isolates are routinely subjected to variable-number tandem-repeat (VNTR) typing to investigate M. tuberculosis transmission. Unexpectedly, cross-border clusters were identified among African refugees in the Netherlands and Denmark, although transmission in those countries was unlikely. Whole-genome sequencing (WGS) was applied to analyze transmission in depth and to assess the precision of VNTR typing. WGS was applied to 40 M. tuberculosis isolates from refugees in the Netherlands and Denmark (most of whom were from the Horn of Africa) that shared the exact same VNTR profile. Cluster investigations were undertaken to identify in-country epidemiological links. Combining WGS results for the isolates (all members of the central Asian strain [CAS]/Delhi genotype), from both European countries, an average genetic distance of 80 single-nucleotide polymorphisms (SNPs) (maximum, 153 SNPs) was observed. The few pairs of isolates with confirmed epidemiological links, except for one pair, had a maximum distance of 12 SNPs. WGS divided this refugee cluster into several subclusters of patients from the same country of origin. Although the M. tuberculosis cases, mainly originating from African countries, shared the exact same VNTR profile, most were clearly distinguished by WGS. The average genetic distance in this specific VNTR cluster was 2 times greater than that in other VNTR clusters. Thus, identical VNTR profiles did not represent recent direct M. tuberculosis transmission for this group of patients. It appears that either these strains from Africa are extremely conserved genetically or there is ongoing transmission of this genotype among refugees on their long migration routes from Africa to Europe. PMID:29167288

A Predominant Variable-Number Tandem-Repeat Cluster of Mycobacterium tuberculosis Isolates among Asylum Seekers in the Netherlands and Denmark, Deciphered by Whole-Genome Sequencing.

PubMed

Jajou, Rana; de Neeling, Albert; Rasmussen, Erik Michael; Norman, Anders; Mulder, Arnout; van Hunen, Rianne; de Vries, Gerard; Haddad, Walid; Anthony, Richard; Lillebaek, Troels; van der Hoek, Wim; van Soolingen, Dick

2018-02-01

In many countries, Mycobacterium tuberculosis isolates are routinely subjected to variable-number tandem-repeat (VNTR) typing to investigate M. tuberculosis transmission. Unexpectedly, cross-border clusters were identified among African refugees in the Netherlands and Denmark, although transmission in those countries was unlikely. Whole-genome sequencing (WGS) was applied to analyze transmission in depth and to assess the precision of VNTR typing. WGS was applied to 40 M. tuberculosis isolates from refugees in the Netherlands and Denmark (most of whom were from the Horn of Africa) that shared the exact same VNTR profile. Cluster investigations were undertaken to identify in-country epidemiological links. Combining WGS results for the isolates (all members of the central Asian strain [CAS]/Delhi genotype), from both European countries, an average genetic distance of 80 single-nucleotide polymorphisms (SNPs) (maximum, 153 SNPs) was observed. The few pairs of isolates with confirmed epidemiological links, except for one pair, had a maximum distance of 12 SNPs. WGS divided this refugee cluster into several subclusters of patients from the same country of origin. Although the M. tuberculosis cases, mainly originating from African countries, shared the exact same VNTR profile, most were clearly distinguished by WGS. The average genetic distance in this specific VNTR cluster was 2 times greater than that in other VNTR clusters. Thus, identical VNTR profiles did not represent recent direct M. tuberculosis transmission for this group of patients. It appears that either these strains from Africa are extremely conserved genetically or there is ongoing transmission of this genotype among refugees on their long migration routes from Africa to Europe. Copyright © 2018 Jajou et al.

Epistasis between dopamine regulating genes identifies a nonlinear response of the human hippocampus during memory tasks.

PubMed

Bertolino, Alessandro; Di Giorgio, Annabella; Blasi, Giuseppe; Sambataro, Fabio; Caforio, Grazia; Sinibaldi, Lorenzo; Latorre, Valeria; Rampino, Antonio; Taurisano, Paolo; Fazio, Leonardo; Romano, Raffaella; Douzgou, Sofia; Popolizio, Teresa; Kolachana, Bhaskar; Nardini, Marcello; Weinberger, Daniel R; Dallapiccola, Bruno

2008-08-01

Dopamine modulation of neuronal activity in prefrontal cortex maps to an inverted U-curve. Dopamine is also an important factor in regulation of hippocampal mediated memory processing. Here, we investigated the effect of genetic variation of dopamine inactivation via catechol-O-methyltransferase (COMT) and the dopamine transporter (DAT) on hippocampal activity in healthy humans during different memory conditions. Using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) in 82 subjects matched for a series of demographic and genetic variables, we studied the effect of the COMT valine (Val)(158)methionine (Met) and the DAT 3' variable number tandem repeat (VNTR) polymorphisms on function of the hippocampus during encoding of recognition memory and during working memory. Our results consistently demonstrated a double dissociation so that DAT 9-repeat carrier alleles modulated activity in the hippocampus in the exact opposite direction of DAT 10/10-repeat alleles based on COMT Val(158)Met genotype during different memory conditions. Similar results were evident in ventrolateral and dorsolateral prefrontal cortex. These findings suggest that genetically determined dopamine signaling during memory processing maps to a nonlinear relationship also in the hippocampus. Our data also demonstrate in human brain epistasis of two genes implicated in dopamine signaling on brain activity during different memory conditions.

solar eclipse 2016

NASA Image and Video Library

2017-12-08

NASA TV video from yesterday's total solar eclipse, when the moon pass directly in front of the sun. It happened from 8:38 to 8:42 p.m. EST March 8. As the moon passed precisely between the sun and Earth – a relatively rare occurrence that happens only about once a year because of the fact that the moon and the sun do not orbit in the exact same plane – it blocked the sun’s bright face, revealing the tenuous and comparatively faint solar atmosphere, the corona. The total eclipse was only visible in parts of Southeast Asia Learn more about this event: youtu.be/MQjPFwcjh9c ‪ NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram ‬

Madrid

NASA Technical Reports Server (NTRS)

2001-01-01

This ASTER image was acquired on July 5, 2000 and covers an area of 25 by 24 km over Madrid, Spain. A historic capital city, Madrid is renowned for its unique charm and its exhilarating cultural life. In the 10th century, a Moorish fortress called Magerit was first built on the site, a plateau 656 meters (2,150 feet) above sea level. Spanish Christians seized the city a century later, although Madrid remained relatively unimportant until 1561. It was then that the Spanish king Philip II chose it as the national capital, largely because of its geographic location in the very heart of the country. Some historic structures from this and later periods still grace the narrow streets of the old section of Madrid, although the Spanish Civil War exacted a heavy toll on the city. The image is located at 40.4 degrees north latitude and 3.7 degrees west longitude.

The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

Using Multimodal Input for Autonomous Decision Making for Unmanned Systems

NASA Technical Reports Server (NTRS)

Neilan, James H.; Cross, Charles; Rothhaar, Paul; Tran, Loc; Motter, Mark; Qualls, Garry; Trujillo, Anna; Allen, B. Danette

2016-01-01

Autonomous decision making in the presence of uncertainly is a deeply studied problem space particularly in the area of autonomous systems operations for land, air, sea, and space vehicles. Various techniques ranging from single algorithm solutions to complex ensemble classifier systems have been utilized in a research context in solving mission critical flight decisions. Realized systems on actual autonomous hardware, however, is a difficult systems integration problem, constituting a majority of applied robotics development timelines. The ability to reliably and repeatedly classify objects during a vehicles mission execution is vital for the vehicle to mitigate both static and dynamic environmental concerns such that the mission may be completed successfully and have the vehicle operate and return safely. In this paper, the Autonomy Incubator proposes and discusses an ensemble learning and recognition system planned for our autonomous framework, AEON, in selected domains, which fuse decision criteria, using prior experience on both the individual classifier layer and the ensemble layer to mitigate environmental uncertainty during operation.

Qualifying a Bonding Process for the Space Interferometry Mission

NASA Technical Reports Server (NTRS)

Joyce, Gretchen P.

2005-01-01

The Space Interferometry Mission consists of three parallel Michelson interferometers that will be capable of detecting extrasolar planets with a high degree of accuracy and precision. High levels of stability must be met in order to fulfill the scientific requirements of this mission. To attain successful measurements the coefficient of thermal expansion between optics and bonding material must be minimized without jeopardizing the integrity of the bonds. Optic-to-optic bonds have been analyzed to better understand variables such as the effects of the coefficient of thermal expansion differences between optics and bonding materials, and materials have been chosen for the project based on these analyses. A study was conducted to determine if a reliable, repeatable process for bonding by wicking adhesive could be obtained using a low-viscosity epoxy and ultra-low expansion glass. A process of creating a methodology of bonding fused silica optics with Z-6020 silane primer and Epo-Tek 301 epoxy will be discussed.

CBERS-03 Satellite Power Supply Subsystem

NASA Astrophysics Data System (ADS)

Almeida, Mario C. P.; Bo, Han

2005-05-01

The second China Brazil Earth Resources Satellite, CBERS-2, was successfully launched on October 21st, 2003 from the Taiyuan Satellite Launch Center, China, through a Long March 4B launcher.The cooperation between China and Brazil for the construction of CBERS satellites is a continued mission and the governments of both countries are committed to building CBERS-3 for the continued and improved services started with the launch of CBERS-1 satellite [1]. Given to its success, the CBERS program is considered as a model for other joint scientific and technological projects between those two countries. CBERS-3 will have new instruments with higher resolution and higher power consumption requirements. The Power Supply Subsystem of CBERS-3 will be a scaled-up version of the one used in the previous missions, but will also present some innovations now possible due to improvements in components, technologies and materials. The modular concept used in the previous design, and repeated in this new mission, will allow the development of the new power subsystem equipments in a straightforward manner.

GO/NO-GO - When is medical hazard mitigation acceptable for launch?

NASA Technical Reports Server (NTRS)

Hamilton, Douglas R.; Polk, James D.

2005-01-01

Medical support of spaceflight missions is composed of complex tasks and decisions that dedicated to maintaining the health and performance of the crew and the completion of mission objectives. Spacecraft represent one of the most complex vehicles built by humans, and are built to very rigorous design specifications. In the course of a Flight Readiness Review (FRR) or a mission itself, the flight surgeon must be able to understand the impact of hazards and risks that may not be completely mitigated by design alone. Some hazards are not mitigated because they are never actually identified. When a hazard is identified, it must be reduced or waivered. Hazards that cannot be designed out of the vehicle or mission, are usually mitigated through other means to bring the residual risk to an acceptable level. This is possible in most engineered systems because failure modes are usually predictable and analysis can include taking these systems to failure. Medical support of space missions is complicated by the inability of flight surgeons to provide "exact" hazard and risk numbers to the NASA engineering community. Taking humans to failure is not an option. Furthermore, medical dogma is mostly comprised of "medical prevention" strategies that mitigate risk by examining the behaviour of a cohort of humans similar to astronauts. Unfortunately, this approach does not lend itself well for predicting the effect of a hazard in the unique environment of space. This presentation will discuss how Medical Operations uses an evidence-based approach to decide if hazard mitigation strategies are adequate to reduce mission risk to acceptable levels. Case studies to be discussed will include: 1. Risk of electrocution risk during EVA 2. Risk of cardiac event risk during long and short duration missions 3. Degraded cabin environmental monitoring on the ISS. Learning Objectives 1.) The audience will understand the challenges of mitigating medical risk caused by nominal and off-nominal mission events. 2.) The audience will understand the process by which medical hazards are identified and mitigated before launch. 3.) The audience will understand the roles and responsibilities of all the other flight control positions in participating in the process of reducing hazards and reducing medical risk to an acceptable level.

ICESat's First Year of Measurements Over the Polar Ice Sheets

NASA Astrophysics Data System (ADS)

Shuman, C. A.

2004-05-01

NASA's Ice, Cloud and Land Elevation Satellite (ICESat) mission was developed to measure changes in elevation of the Greenland and Antarctic ice sheets. Its primary mission goal is to significantly refine estimates of polar ice sheet mass balance. Obtaining precise, spatially dense, ice sheet elevations through time is the first step towards this goal. ICESat data will then enable study of associations between observed ice changes and dynamic or climatic forcing factors, and thus enable improved estimation of the present and future contributions of the ice sheets to global sea level rise. ICESat was launched on January 12, 2003 and acquired science data from February 20th to March 29th with the first of the three lasers of the Geoscience Laser Altimeter System (GLAS). Data acquisition with the second laser began on September 25th and continued until November 18th, 2003. For one-year change detection, the second laser is scheduled for operation from approximately February 17th to March 20th, 2004. Additional operational periods will be selected to 1) enable periodic measurements through the year, and 2) to support of other NASA Earth Science Enterprise missions and activities. To obtain these precise ice sheet elevations, GLAS has a 1064 nm wavelength laser operating at 40 Hz with a designed range precision of about 10 cm. The laser footprints are about 70 m in diameter on the Earth's surface and are spaced every 172 m along-track. The on-board GPS receiver enables radial orbit determinations to an accuracy better than 5 cm. The star-tracking attitude-determination system will enable laser footprints to be located to 6 m horizontally when attitude calibration is completed. The orbital altitude averages 600 km at an inclination of 94 degrees with coverage extending from 86 degrees N and S latitude. The spacecraft attitude can be controlled to point the laser beam to within 50 m of surface reference tracks over the ice sheets and to point off-nadir up to 5 degrees to targets of interest. ICESat was designed to operate for 3 to 5 years but laser lifetime is uncertain and may not achieve this goal based on a detailed review following the failure of Laser 1. However, the results from the first full year of ICESat operations demonstrate that the GLAS instrument can measure ice sheet elevations with unprecedented accuracy. This presentation will show ice sheet results using crossover and exact repeat track analyses. Additional data using the remaining lasers will further demonstrate the capability to measure ice sheet elevation changes and improve mass balance assessments of the great polar ice sheets.

Improved variance estimation of classification performance via reduction of bias caused by small sample size.

PubMed

Wickenberg-Bolin, Ulrika; Göransson, Hanna; Fryknäs, Mårten; Gustafsson, Mats G; Isaksson, Anders

2006-03-13

Supervised learning for classification of cancer employs a set of design examples to learn how to discriminate between tumors. In practice it is crucial to confirm that the classifier is robust with good generalization performance to new examples, or at least that it performs better than random guessing. A suggested alternative is to obtain a confidence interval of the error rate using repeated design and test sets selected from available examples. However, it is known that even in the ideal situation of repeated designs and tests with completely novel samples in each cycle, a small test set size leads to a large bias in the estimate of the true variance between design sets. Therefore different methods for small sample performance estimation such as a recently proposed procedure called Repeated Random Sampling (RSS) is also expected to result in heavily biased estimates, which in turn translates into biased confidence intervals. Here we explore such biases and develop a refined algorithm called Repeated Independent Design and Test (RIDT). Our simulations reveal that repeated designs and tests based on resampling in a fixed bag of samples yield a biased variance estimate. We also demonstrate that it is possible to obtain an improved variance estimate by means of a procedure that explicitly models how this bias depends on the number of samples used for testing. For the special case of repeated designs and tests using new samples for each design and test, we present an exact analytical expression for how the expected value of the bias decreases with the size of the test set. We show that via modeling and subsequent reduction of the small sample bias, it is possible to obtain an improved estimate of the variance of classifier performance between design sets. However, the uncertainty of the variance estimate is large in the simulations performed indicating that the method in its present form cannot be directly applied to small data sets.

Instructor-Facilitated vs. Stand-Alone Tactical Game Training

DTIC Science & Technology

2009-01-01

Mixed Factor Repeated-Measures ANOVA showed that the two groups of leaders did not differ significantly on the time they used to complete either the...game training on tactical decision making. Thirty- two leaders were assigned to complete two urban operations- based missions (patrol and defense...using the SimFX game. These leaders worked under the direction of an instructor and interacted with peers. Thirty-seven more leaders completed the two

FIRE - Flyby of Io with Repeat Encounters: A conceptual design for a New Frontiers mission to Io

NASA Astrophysics Data System (ADS)

Suer, Terry-Ann; Padovan, Sebastiano; Whitten, Jennifer L.; Potter, Ross W. K.; Shkolyar, Svetlana; Cable, Morgan; Walker, Catherine; Szalay, Jamey; Parker, Charles; Cumbers, John; Gentry, Diana; Harrison, Tanya; Naidu, Shantanu; Trammell, Harold J.; Reimuller, Jason; Budney, Charles J.; Lowes, Leslie L.

2017-09-01

A conceptual design is presented for a low complexity, heritage-based flyby mission to Io, Jupiter's innermost Galilean satellite and the most volcanically active body in the Solar System. The design addresses the 2011 Decadal Survey's recommendation for a New Frontiers class mission to Io and is based upon the result of the June 2012 NASA-JPL Planetary Science Summer School. A science payload is proposed to investigate the link between the structure of Io's interior, its volcanic activity, its surface composition, and its tectonics. A study of Io's atmospheric processes and Io's role in the Jovian magnetosphere is also planned. The instrument suite includes a visible/near-IR imager, a magnetic field and plasma suite, a dust analyzer, and a gimbaled high gain antenna to perform radio science. Payload activity and spacecraft operations would be powered by three Advanced Stirling Radioisotope Generators (ASRG). The primary mission includes 10 flybys with close-encounter altitudes as low as 100 km. The mission risks are mitigated by ensuring that relevant components are radiation tolerant and by using redundancy and flight-proven parts in the design. The spacecraft would be launched on an Atlas V rocket with a delta-v of 1.3 km/s. Three gravity assists (Venus, Earth, Earth) would be used to reach the Jupiter system in a 6-year cruise. The resulting concept demonstrates the rich scientific return of a flyby mission to Io.

Analysis of the behavior of a wiper blade around the reversal in consideration of dynamic and static friction

NASA Astrophysics Data System (ADS)

Unno, M.; Shibata, A.; Yabuno, H.; Yanagisawa, D.; Nakano, T.

2017-04-01

Reducing noise generated by automobile windshield wipers during reversals is a desirable feature. For this purpose, details of the behavior of the wiper blade need to be ascertained. In this study, we present theoretical and experimental clarification of this behavior during reversals. Using simulation algorithms to consider exactly the effects of dynamic and static friction, we determined theoretical predictions for the vibrational response caused by friction and the response frequency and compared these results with experimental ones obtained from a mock-up incorporating an actual wiper blade. We introduce an analytical link model with two degrees of freedom and consider two types of states at the blade tip. In the stick and the slip states, static friction and dynamic friction, respectively, act on the blade tip. In the theoretical approach, the static friction is expressed by a set-valued function. The transition between the two states is repeated and an evaluation of an exact transition time leads to an accurate prediction of the behavior of the wiper system. In the analysis, the slack variable method is used to find the exact transition time. Assuming low blade speeds during reversal, a parameter study indicates that the blade tip transitions between slip and stick states and the frequency of the vibration caused by this transitions is close to the natural frequency of the neck of the wiper blade. The theoretical predictions are in good agreement with experimental observations.

Verify Occulter Deployment Tolerances as Part of NASA's Technology Development for Exoplanet Missions

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Shaklan, S.; Lisman, D.; Thomson, M.; Webb, D.; Cady, E.; Marks, G. W.; Lo, A.

2013-01-01

In support of NASA's Exoplanet Exploration Program and the Technology Development for Exoplanet Missions (TDEM), we recently completed a 2 year study of the manufacturability and metrology of starshade petals. An external occult is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. This poster presents the results of our successful first TDEM that demonstrated an occulter petal could be built and measured to an accuracy consistent with close to 10^-10 contrast. We also present the progress in our second TDEM to demonstrate the next critical technology milestone: precision deployment of the central truss and petals to the necessary accuracy. We have completed manufacture of four sub-scale petals and a central hub to fit with an existing deployable truss. We show the plans for repeated stow and deploy tests of the assembly and the metrology to confirm that each deploy repeatably meets the absolute positioning requirements of the petals (better than 1.0 mm).

Orthostatic Intolerance After ISS and Space Shuttle Missions.

PubMed

Lee, Stuart M C; Feiveson, Alan H; Stein, Sydney; Stenger, Michael B; Platts, Steven H

2015-12-01

Cardiovascular deconditioning apparently progresses with flight duration, resulting in a greater incidence of orthostatic intolerance following long-duration missions. Therefore, we anticipated that the proportion of astronauts who could not complete an orthostatic tilt test (OTT) would be higher on landing day and the number of days to recover greater after International Space Station (ISS) than after Space Shuttle missions. There were 20 ISS and 65 Shuttle astronauts who participated in 10-min 80° head-up tilt tests 10 d before launch, on landing day (R+0), and 3 d after landing (R+3). Fisher's Exact Test was used to compare the ability of ISS and Shuttle astronauts to complete the OTT. Cox regression was used to identify cardiovascular parameters associated with OTT completion and mixed model analysis was used to compare the change and recovery rates between groups. The proportion of astronauts who completed the OTT on R+0 (2 of 6) was less in ISS than in Shuttle astronauts (52 of 65). On R+3, 13 of 15 and 19 of 19 of the ISS and Shuttle astronauts, respectively, completed the OTT. An index comprised of stroke volume and diastolic blood pressure provided a good prediction of OTT completion and was altered by spaceflight similarly for both astronaut groups, but recovery was slower in ISS than in Shuttle astronauts. The proportion of ISS astronauts who could not complete the OTT on R+0 was greater and the recovery rate slower after ISS compared to Shuttle missions. Thus, mission planners and crew surgeons should anticipate the need to tailor scheduled activities and level of medical support to accommodate protracted recovery after long-duration microgravity exposures.

Circular revisit orbits design for responsive mission over a single target

NASA Astrophysics Data System (ADS)

Li, Taibo; Xiang, Junhua; Wang, Zhaokui; Zhang, Yulin

2016-10-01

The responsive orbits play a key role in addressing the mission of Operationally Responsive Space (ORS) because of their capabilities. These capabilities are usually focused on supporting specific targets as opposed to providing global coverage. One subtype of responsive orbits is repeat coverage orbit which is nearly circular in most remote sensing applications. This paper deals with a special kind of repeating ground track orbit, referred to as circular revisit orbit. Different from traditional repeat coverage orbits, a satellite on circular revisit orbit can visit a target site at both the ascending and descending stages in one revisit cycle. This typology of trajectory allows a halving of the traditional revisit time and does a favor to get useful information for responsive applications. However the previous reported numerical methods in some references often cost lots of computation or fail to obtain such orbits. To overcome this difficulty, an analytical method to determine the existence conditions of the solutions to revisit orbits is presented in this paper. To this end, the mathematical model of circular revisit orbit is established under the central gravity model and the J2 perturbation. A constraint function of the circular revisit orbit is introduced, and the monotonicity of that function has been studied. The existent conditions and the number of such orbits are naturally worked out. Taking the launch cost into consideration, optimal design model of circular revisit orbit is established to achieve a best orbit which visits a target twice a day in the morning and in the afternoon respectively for several days. The result shows that it is effective to apply circular revisit orbits in responsive application such as reconnoiter of natural disaster.

Titan's atmosphere and surface in 2026: the AVIATR Titan Airplane Mission

NASA Astrophysics Data System (ADS)

McKay, Chris; Barnes, Jason W.; Lemke, Lawrence; Beyer, Ross A.; Radebaugh, Jani; Atkinson, David; Flasar, F. Michael

2010-04-01

This poster describes the scientific, engineering, and operations planning for a Discovery / New Frontiers class Titan airplane mission, AVIATR (Aerial Vehicle for In-situ and Airborne Titan Reconnaissance). The mission would focus on Titan's surface and atmospheric diversity, using high-resolution imaging, near-infrared spectroscopy, a haze spectrometer, and atmospheric structure measurements. Previous mission studies have elected to use hot-air balloons to achieve similar science goals. These hot-air balloon concepts require the waste heat from inefficient thermocouple-based Radioisotope Thermoelectric Generators (RTGs) for buoyancy. New Advanced Stirling Radioisotope Generators (ASRGs) are much more efficient than RTGs both in terms of power produced per gram of plutonium-238 and the total watts-per-kilogram of the power unit itself. However, they are so efficient that they are much less effective for use in heating a hot-air balloon. Similarly, old-style RTGs produce insufficient specific power for heavier-than-air flight, but the use of 2 ASRGs can support a 120 kg airplane for a long-duration mission at Titan. The AVIATR airplane concept has several advantages in its science capabilities relative to a balloon, including the ability to target any site of interest, remaining on the dayside, stereo and repeat coverage, and easy altitude changes. It also possesses engineering advantages over a balloon like low total mass, a more straightforward deployment sequence, direct-to-Earth communications capability, and a more robust airframe.

Recreation Embedded State Tuning for Optimal Readiness and Effectiveness (RESTORE)

NASA Technical Reports Server (NTRS)

Pope, Alan T.; Prinzel, Lawrence J., III

2005-01-01

Physiological self-regulation training is a behavioral medicine intervention that has demonstrated capability to improve psychophysiological coping responses to stressful experiences and to foster optimal behavioral and cognitive performance. Once developed, these psychophysiological skills require regular practice for maintenance. A concomitant benefit of these physiologically monitored practice sessions is the opportunity to track crew psychophysiological responses to the challenges of the practice task in order to detect shifts in adaptability that may foretell performance degradation. Long-duration missions will include crew recreation periods that will afford physiological self-regulation training opportunities. However, to promote adherence to the regimen, the practice experience that occupies their recreation time must be perceived by the crew as engaging and entertaining throughout repeated reinforcement sessions on long-duration missions. NASA biocybernetic technologies and publications have developed a closed-loop concept that involves adjusting or modulating (cybernetic, for governing) a person's task environment based upon a comparison of that person's physiological responses (bio-) with a training or performance criterion. This approach affords the opportunity to deliver physiological self-regulation training in an entertaining and motivating fashion and can also be employed to create a conditioned association between effective performance state and task execution behaviors, while enabling tracking of individuals psychophysiological status over time in the context of an interactive task challenge. This paper describes the aerospace spin-off technologies in this training application area as well as the current spin-back application of the technologies to long-duration missions - the Recreation Embedded State Tuning for Optimal Readiness and Effectiveness (RESTORE) concept. The RESTORE technology is designed to provide a physiological self-regulation training countermeasure for maintaining and reinforcing cognitive readiness, resilience under psychological stress, and effective mood states in long-duration crews. The technology consists of a system for delivering physiological self-regulation training and for tracking crew central and autonomic nervous system function; the system interface is designed to be experienced as engaging and entertaining throughout repeated training sessions on long-duration missions. Consequently, this self-management technology has threefold capability for recreation, behavioral health problem prophylaxis and remediation, and psychophysiological assay. The RESTORE concept aims to reduce the risk of future manned exploration missions by enhancing the capability of individual crewmembers to self-regulate cognitive states through recreation-embedded training protocols to effectively deal with the psychological toll of long-duration space flight.

A Survey of Cost Estimating Methodologies for Distributed Spacecraft Missions

NASA Technical Reports Server (NTRS)

Foreman, Veronica L.; Le Moigne, Jacqueline; de Weck, Oliver L.

2016-01-01

Satellite constellations and Distributed Spacecraft Mission (DSM) architectures offer unique benefits to Earth observation scientists and unique challenges to cost estimators. The Cost and Risk (CR) module of the Tradespace Analysis Tool for Constellations (TAT-C) being developed by NASA Goddard seeks to address some of these challenges by providing a new approach to cost modeling, which aggregates existing Cost Estimating Relationships (CER) from respected sources, cost estimating best practices, and data from existing and proposed satellite designs. Cost estimation through this tool is approached from two perspectives: parametric cost estimating relationships and analogous cost estimation techniques. The dual approach utilized within the TAT-C CR module is intended to address prevailing concerns regarding early design stage cost estimates, and offer increased transparency and fidelity by offering two preliminary perspectives on mission cost. This work outlines the existing cost model, details assumptions built into the model, and explains what measures have been taken to address the particular challenges of constellation cost estimating. The risk estimation portion of the TAT-C CR module is still in development and will be presented in future work. The cost estimate produced by the CR module is not intended to be an exact mission valuation, but rather a comparative tool to assist in the exploration of the constellation design tradespace. Previous work has noted that estimating the cost of satellite constellations is difficult given that no comprehensive model for constellation cost estimation has yet been developed, and as such, quantitative assessment of multiple spacecraft missions has many remaining areas of uncertainty. By incorporating well-established CERs with preliminary approaches to approaching these uncertainties, the CR module offers more complete approach to constellation costing than has previously been available to mission architects or Earth scientists seeking to leverage the capabilities of multiple spacecraft working in support of a common goal.

Lessons Learned from the Clementine Mission

NASA Technical Reports Server (NTRS)

1997-01-01

According to BMDO, the Clementine mission achieved many of its technology objectives during its flight to the Moon in early 1994 but, because of a software error, was unable to test the autonomous tracking of a cold target. The preliminary analyses of the returned lunar data suggest that valuable scientific measurements were made on several important topics but that COMPLEX's highest-priority objectives for lunar science were not achieved. This is not surprising given that the rationale for Clementine was technological rather than scientific. COMPLEX lists below a few of the lessons that may be learned from Clementine. Although the Clementine mission was not conceived as a NASA science mission exactly like those planned for the Discovery program, many operational aspects of the two are similar. It is therefore worthwhile to understand the strengths and faults of the Clementine approach. Some elements of the Clementine operation that led to the mission's success include the following: (1) The mission's achievements were the responsibility of a single organization and its manager, which made that organization and that individual accountable for the final outcome; (2) The sponsor adopted a hands-off approach and set a minimum number of reviews (three); (3) The sponsor accepted a reasonable amount of risk and allowed the project team to make the trade-offs necessary to minimize the mission's risks while still accomplishing all its primary objectives; and (4) The development schedule was brief and the agreed-on funding (and funding profile) was adhered to. Among the operational shortcomings of Clementine were the following: (1) An overly ambitious schedule and a slightly lean budget (meaning insufficient time for software development and testing, and leading ultimately to human exhaustion); and (2) No support for data calibration, reduction, and analysis. The principal lesson to be learned in this category is that any benefits from the constructive application of higher risk for lower cost and faster schedule will be lost if the schedule does not allow adequate time for the development of all essential systems or makes no allowance for human frailties. Another lesson to be drawn is that despite its limitations, if judged strictly as a science mission, Clementine attested that significant scientific information can be gathered during a technology-demonstration mission. In the current era of limited funds, when science missions will be infrequent, the opportunity to fly scientific instruments aboard missions whose objectives might be other than science must be seized and, indeed, encouraged. During such opportunities it would be inexcusable to do second-class science. Thus the scientific community must be actively involved in such projects from their initiation.

Documentation for the machine-readable version of the Revised S210 Catalog of Far-Ultraviolet Objects (Page, Carruthers and Heckathorn 1982)

NASA Technical Reports Server (NTRS)

Warren, W. H., Jr.

1984-01-01

A detailed description of the machine-readable revised catalog as it is currently being distributed from the Astronomical Data Center is given. This catalog of star images was compiled from imagery obtained by the Naval Research Laboratory (NRL) Far-Ultraviolet Camera/Spectrograph (Experiments S201) operated from 21 to 23 April 1972 on the lunar surface during the Apollo 16 mission. The documentation includes a detailed data format description, a table of indigenous characteristics of the magnetic tape file, and a sample listing of data records exactly as they are presented in the machine-readable version.

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

PubMed

You, Zhongsheng; Chahwan, Charly; Bailis, Julie; Hunter, Tony; Russell, Paul

2005-07-01

ATM has a central role in controlling the cellular responses to DNA damage. It and other phosphoinositide 3-kinase-related kinases (PIKKs) have giant helical HEAT repeat domains in their amino-terminal regions. The functions of these domains in PIKKs are not well understood. ATM activation in response to DNA damage appears to be regulated by the Mre11-Rad50-Nbs1 (MRN) complex, although the exact functional relationship between the MRN complex and ATM is uncertain. Here we show that two pairs of HEAT repeats in fission yeast ATM (Tel1) interact with an FXF/Y motif at the C terminus of Nbs1. This interaction resembles nucleoporin FXFG motif binding to HEAT repeats in importin-beta. Budding yeast Nbs1 (Xrs2) appears to have two FXF/Y motifs that interact with Tel1 (ATM). In Xenopus egg extracts, the C terminus of Nbs1 recruits ATM to damaged DNA, where it is subsequently autophosphorylated. This interaction is essential for ATM activation. A C-terminal 147-amino-acid fragment of Nbs1 that has the Mre11- and ATM-binding domains can restore ATM activation in an Nbs1-depleted extract. We conclude that an interaction between specific HEAT repeats in ATM and the C-terminal FXF/Y domain of Nbs1 is essential for ATM activation. We propose that conformational changes in the MRN complex that occur upon binding to damaged DNA are transmitted through the FXF/Y-HEAT interface to activate ATM. This interaction also retains active ATM at sites of DNA damage.

Source Repeatability of Time-Lapse Offset VSP Surveys for Monitoring CO2 Injection

NASA Astrophysics Data System (ADS)

Zhang, Z.; Huang, L.; Rutledge, J. T.; Denli, H.; Zhang, H.; McPherson, B. J.; Grigg, R.

2009-12-01

Time-lapse vertical seismic profiling (VSP) surveys have the potential to remotely track the migration of injected CO2 within a geologic formation. To accurately detect small changes due to CO2 injection, the sources of time-lapse VSP surveys must be located exactly at the same positions. However, in practice, the source locations can vary from one survey to another survey. Our numerical simulations demonstrate that a variation of a few meters in the VSP source locations can result in significant changes in time-lapse seismograms. To address the source repeatability issue, we apply double-difference tomography to downgoing waves of time-lapse offset VSP data to invert for the source locations and the velocity structures simultaneously. In collaboration with Resolute Natural Resources, Navajo National Oil and Gas Company, and the Southwest Regional Partnership on Carbon Sequestration under the support of the U.S. Department of Energy’s National Energy Technology Laboratory, one baseline and two repeat offset VSP datasets were acquired in 2007-2009 for monitoring CO2 injection at the Aneth oil field in Utah. A cemented geophone string was used to acquire the data for one zero-offset and seven offset source locations. During the data acquisition, there was some uncertainty in the repeatability of the source locations relative to the baseline survey. Our double-difference tomography results of the Aneth time-lapse VSP data show that the source locations for different surveys are separated up to a few meters. Accounting for these source location variations during VSP data analysis will improve reliability of time-lapse VSP monitoring.

The Potential for Hosted Payloads at NASA

NASA Technical Reports Server (NTRS)

Andraschko, Mark; Antol, Jeffrey; Baize, Rosemary; Horan, Stephen; Neil, Doreen; Rinsland, Pamela; Zaiceva, Rita

2012-01-01

The 2010 National Space Policy encourages federal agencies to actively explore the use of inventive, nontraditional arrangements for acquiring commercial space goods and services to meet United States Government requirements, including...hosting government capabilities on commercial spacecraft. NASA's Science Mission Directorate has taken an important step towards this goal by adding an option for hosted payload responses to its recent Announcement of Opportunity (AO) for Earth Venture-2 missions. Since NASA selects a significant portion of its science missions through a competitive process, it is useful to understand the implications that this process has on the feasibility of successfully proposing a commercially hosted payload mission. This paper describes some of the impediments associated with proposing a hosted payload mission to NASA, and offers suggestions on how these impediments might be addressed. Commercially hosted payloads provide a novel way to serve the needs of the science and technology demonstration communities at a fraction of the cost of a traditional Geostationary Earth Orbit (GEO) mission. The commercial communications industry launches over 20 satellites to GEO each year. By exercising this repeatable commercial paradigm of privately financed access to space with proven vendors, NASA can achieve science goals at a significantly lower cost than the current dedicated spacecraft and launch vehicle approach affords. Commercial hosting could open up a new realm of opportunities for NASA science missions to make measurements from GEO. This paper also briefly describes two GEO missions recommended by the National Academies of Science Earth Science Decadal Survey, the Geostationary Coastal and Air Pollution Events (GEO-CAPE) mission and the Precipitation and All-weather Temperature and Humidity (PATH) mission. Hosted payload missions recently selected for implementation by the Office of the Chief Technologist are also discussed. Finally, there are technical differences specific to hosted payloads and the GEO environment that must be considered when planning and developing a hosted payload mission. This paper addresses some of payload accommodation differences from the typical NASA LEO mission, including spacecraft interfaces, attitude control and knowledge, communications, data handling, mission operations, ground systems, and the thermal, radiation, and electromagnetic environment. The paper also discusses technical and programmatic differences such as limits to NASA's involvement with commercial quality assurance processes to conform to the commercial schedule and minimizing the price that makes hosted payloads an attractive option.

Mind-Sets and Missiles: A First Hand Account of the Cuban Missile Crisis

DTIC Science & Technology

2009-09-01

was still in session, Deputy Secretary of Defense Roswell Gilpatric gave a speech to the Business Council at White Sulfur Springs, West Virginia...Bundy and Roswell Gilpatric in Paris to warn them that he believed the Soviets would place offensive missiles in Cuba. In a series of cables between...repeat missions of recent reconnaissance operations which [Deputy Secretary of Defense Roswell ] Gilpatric advises informative. Also I support use of R

Assimilation of repeated woody biomass observations constrains decadal ecosystem carbon cycle uncertainty in aggrading forests

NASA Astrophysics Data System (ADS)

Smallman, T. L.; Exbrayat, J.-F.; Mencuccini, M.; Bloom, A. A.; Williams, M.

2017-03-01

Forest carbon sink strengths are governed by plant growth, mineralization of dead organic matter, and disturbance. Across landscapes, remote sensing can provide information about aboveground states of forests and this information can be linked to models to estimate carbon cycling in forests close to steady state. For aggrading forests this approach is more challenging and has not been demonstrated. Here we apply a Bayesian approach, linking a simple model to a range of data, to evaluate their information content, for two aggrading forests. We compare high information content analyses using local observations with retrievals using progressively sparser remotely sensed information (repeated, single, and no woody biomass observations). The net biome productivity of both forests is constrained to be a net sink with <2 Mg C ha-1 yr-1 variation across the range of inputs. However, the sequestration of particular carbon pool(s) varies with assimilated biomass information. Assimilation of repeated biomass observations reduces uncertainty and/or bias in all ecosystem C pools not just wood, compared to analyses using single or no stock information. As verification, our repeated biomass analysis explains 78-86% of variation in litter dynamics at one forest, while at the second forest total dead organic matter estimates are within observational uncertainty. The uncertainty of retrieved ecosystem traits in the repeated biomass analysis is reduced by up to 50% compared to analyses with less biomass information. This study quantifies the importance of repeated woody observations in constraining the dynamics of both wood and dead organic matter, highlighting the benefit of proposed remote sensing missions.

Conscious Sedation Procedures Using Intravenous Midazolam for Dental Care in Patients with Different Cognitive Profiles: A Prospective Study of Effectiveness and Safety

PubMed Central

Collado, Valérie; Faulks, Denise; Nicolas, Emmanuel; Hennequin, Martine

2013-01-01

The use of midazolam for dental care in patients with intellectual disability is poorly documented. This study aimed to evaluate the effectiveness and safety of conscious sedation procedures using intravenous midazolam in adults and children with intellectual disability (ID) compared to dentally anxious patients (DA). Ninety-eight patients with ID and 44 patients with DA programmed for intravenous midazolam participated in the study over 187 and 133 sessions, respectively. Evaluation criteria were success of dental treatment, cooperation level (modified Venham scale), and occurrence of adverse effects. The mean intravenous dose administered was 8.8±4.9 mg and 9.8±4.1 mg in ID and DA sessions respectively (t-test, NS). 50% N2O/O2 was administered during cannulation in 51% of ID sessions and 61% of DA sessions (NS, Fisher exact test). Oral or rectal midazolam premedication was administered for cannulation in 31% of ID sessions and 3% of DA sessions (p<0,001, Fisher exact test). Dental treatment was successful in 9 out of 10 sessions for both groups. Minor adverse effects occurred in 16.6% and 6.8% of ID and DA sessions respectively (p = 0.01, Fisher exact test). Patients with ID were more often very disturbed during cannulation (25.4% ID vs. 3.9% DA sessions) and were less often relaxed after induction (58.9% ID vs. 90.3% DA) and during dental treatment (39.5% ID vs. 59.7% DA) (p<0.001, Fisher exact test) than patients with DA. When midazolam sedation was repeated, cooperation improved for both groups. Conscious sedation procedures using intravenous midazolam, with or without premedication and/or inhalation sedation (50% N2O/O2), were shown to be safe and effective in patients with intellectual disability when administered by dentists. PMID:23940729

New Mission Concept Study: Energetic X-Ray Imaging Survey Telescope (EXIST)

NASA Technical Reports Server (NTRS)

1998-01-01

This Report summarizes the activity carried out under the New Mission Concept (NMC) study for a mission to conduct a sensitive all-sky imaging survey in the hard x-ray (HX) band (approximately 10-600 keV). The Energetic X-ray Imaging Survey Telescope (EXIST) mission was originally proposed for this NMC study and was then subsequently proposed for a MIDEX mission as part of this study effort. Development of the EXIST (and related) concepts continues for a future flight proposal. The hard x-ray band (approximately 10-600 keV) is nearly the final band of the astronomical spectrum still without a sensitive imaging all-sky survey. This is despite the enormous potential of this band to address a wide range of fundamental and timely objectives - from the origin and physical mechanisms of cosmological gamma-ray bursts (GRBs) to the processes on strongly magnetic neutron stars that produce soft gamma-repeaters and bursting pulsars; from the study of active galactic nuclei (AGN) and quasars to the origin and evolution of the hard x-ray diffuse background; from the nature and number of black holes and neutron stars and the accretion processes onto them to the extreme non-thermal flares of normal stars; and from searches for expected diffuse (but relatively compact) nuclear line (Ti-44) emission in uncatalogued supernova remnants to diffuse non-thermal inverse Compton emission from galaxy clusters. A high sensitivity all-sky survey mission in the hard x-ray band, with imaging to both address source confusion and time-variable background radiations, is very much needed.

Acoustic Emission Health Monitoring of Fill Purge COPV's Used in Aerospace and Automotive Applications and Designed for Long Cycle Life

NASA Technical Reports Server (NTRS)

Waller, Jess

2013-01-01

Cumulative composite damage in composite pressure vessels (CPVs) currently is not monitored on-orbit. Consequently, hazards due to catastrophic burst before leak (BBL) or compromised CPV reliability cannot be ascertained or mitigated, posing a risk to crew and mission assurance. The energy associated with CPV rupture can be significant, especially with high pressure gases are under containment, and the energy releases can be severe enough to cause injury, death, loss of assets or mission. Dual-Use Rationale: CPVs similar to those used by NASA on ISS, for example, are finding increasing use in automotive and transportation industry applications. These CPVs generally have a nonload sharing liner and are repeatedly filled over their service lifetime, typically with hydrogen or compressed natural gas (CNG). The same structural health monitoring equipment and software developed by NASA WSTF for evaluating, in real-time, the health of NASA CPVs on ISS will be used to evaluate the health of automotive CPVs, the only differences being the type and design of the CPV, and the in-service lifetime pressure histories. HSF Need(s)/Performance Characteristic(s) Supported: 1) Enable on-board vehicle systems management for mission critical functions at destinations with > 3 second time delay 2) Enable autonomous nominal operations and FDIR for crewed and un-crewed systems 3) Reduce on-board crew time to sustain and manage vehicle by factor of 2x at destinations with > 6 second time delay (see Crew Autonomy sheet) 4) Reduce earth-based mission ops "back room engineering" requirements for distant mission support delay (see Mission Autonomy sheet)

A marker placement laser device for improving repeatability in 3D-foot motion analysis.

PubMed

Kalkum, Eva; van Drongelen, Stefan; Mussler, Johannes; Wolf, Sebastian I; Kuni, Benita

2016-02-01

In 3D gait analysis, the repeated positioning of markers is associated with a high error rate, particularly when using a complex foot model with many markers. Therefore, a marker placement laser device was developed that ensures a reliable repositioning of markers. We report the development and reliability of this device for the foot at different tape conditions. In 38 subjects, markers were placed at the foot according to the Heidelberg foot measurement method. Subjects were tested barefoot and barefoot with three different tape conditions. For all conditions, a static standing trial was captured. We analyzed differences in distances between markers and the intra-class correlation coefficients (ICC). Small differences between the conditions (0.03-3.28 mm) and excellent ICCs (0.91-0.97 mm) were found for all parameters. The laser marker placement device appeared to be a reliable method to place markers on a tape at previously palpated positions and ensures an exact position. The device could find a wide application in different clinical research fields. Copyright © 2015 Elsevier B.V. All rights reserved.

Wavelength shifting of intra-cavity photons: Adiabatic wavelength tuning in rapidly wavelength-swept lasers

PubMed Central

Jirauschek, Christian; Huber, Robert

2015-01-01

We analyze the physics behind the newest generation of rapidly wavelength tunable sources for optical coherence tomography (OCT), retaining a single longitudinal cavity mode during operation without repeated build up of lasing. In this context, we theoretically investigate the currently existing concepts of rapidly wavelength-swept lasers based on tuning of the cavity length or refractive index, leading to an altered optical path length inside the resonator. Specifically, we consider vertical-cavity surface-emitting lasers (VCSELs) with microelectromechanical system (MEMS) mirrors as well as Fourier domain mode-locked (FDML) and Vernier-tuned distributed Bragg reflector (VT-DBR) lasers. Based on heuristic arguments and exact analytical solutions of Maxwell’s equations for a fundamental laser resonator model, we show that adiabatic wavelength tuning is achieved, i.e., hopping between cavity modes associated with a repeated build up of lasing is avoided, and the photon number is conserved. As a consequence, no fundamental limit exists for the wavelength tuning speed, in principle enabling wide-range wavelength sweeps at arbitrary tuning speeds with narrow instantaneous linewidth. PMID:26203373

DNABIT Compress - Genome compression algorithm.

PubMed

Rajarajeswari, Pothuraju; Apparao, Allam

2011-01-22

Data compression is concerned with how information is organized in data. Efficient storage means removal of redundancy from the data being stored in the DNA molecule. Data compression algorithms remove redundancy and are used to understand biologically important molecules. We present a compression algorithm, "DNABIT Compress" for DNA sequences based on a novel algorithm of assigning binary bits for smaller segments of DNA bases to compress both repetitive and non repetitive DNA sequence. Our proposed algorithm achieves the best compression ratio for DNA sequences for larger genome. Significantly better compression results show that "DNABIT Compress" algorithm is the best among the remaining compression algorithms. While achieving the best compression ratios for DNA sequences (Genomes),our new DNABIT Compress algorithm significantly improves the running time of all previous DNA compression programs. Assigning binary bits (Unique BIT CODE) for (Exact Repeats, Reverse Repeats) fragments of DNA sequence is also a unique concept introduced in this algorithm for the first time in DNA compression. This proposed new algorithm could achieve the best compression ratio as much as 1.58 bits/bases where the existing best methods could not achieve a ratio less than 1.72 bits/bases.

A unique chromatin complex occupies young α-satellite arrays of human centromeres

PubMed Central

Henikoff, Jorja G.; Thakur, Jitendra; Kasinathan, Sivakanthan; Henikoff, Steven

2015-01-01

The intractability of homogeneous α-satellite arrays has impeded understanding of human centromeres. Artificial centromeres are produced from higher-order repeats (HORs) present at centromere edges, although the exact sequences and chromatin conformations of centromere cores remain unknown. We use high-resolution chromatin immunoprecipitation (ChIP) of centromere components followed by clustering of sequence data as an unbiased approach to identify functional centromere sequences. We find that specific dimeric α-satellite units shared by multiple individuals dominate functional human centromeres. We identify two recently homogenized α-satellite dimers that are occupied by precisely positioned CENP-A (cenH3) nucleosomes with two ~100–base pair (bp) DNA wraps in tandem separated by a CENP-B/CENP-C–containing linker, whereas pericentromeric HORs show diffuse positioning. Precise positioning is largely maintained, whereas abundance decreases exponentially with divergence, which suggests that young α-satellite dimers with paired ~100-bp particles mediate evolution of functional human centromeres. Our unbiased strategy for identifying functional centromeric sequences should be generally applicable to tandem repeat arrays that dominate the centromeres of most eukaryotes. PMID:25927077

Interstitial telomeric repeats are not preferentially involved in radiation-induced chromosome aberrations in human cells.

PubMed

Desmaze, C; Pirzio, L M; Blaise, R; Mondello, C; Giulotto, E; Murnane, J P; Sabatier, L

2004-01-01

Telomeric repeat sequences, located at the end of eukaryotic chromosomes, have been detected at intrachromosomal locations in many species. Large blocks of telomeric sequences are located near the centromeres in hamster cells, and have been reported to break spontaneously or after exposure to ionizing radiation, leading to chromosome aberrations. In human cells, interstitial telomeric sequences (ITS) can be composed of short tracts of telomeric repeats (less than twenty), or of longer stretches of exact and degenerated hexanucleotides, mainly localized at subtelomeres. In this paper, we analyzed the radiation sensitivity of a naturally occurring short ITS localized in 2q31 and we found that this region is not a hot spot of radiation-induced chromosome breaks. We then selected a human cell line in which approximately 800 bp of telomeric DNA had been introduced by transfection into an internal euchromatic chromosomal region in chromosome 4q. In parallel, a cell line containing the plasmid without telomeric sequences was also analyzed. Both regions containing the transfected plasmids showed a higher frequency of radiation-induced breaks than expected, indicating that the instability of the regions containing the transfected sequences is not due to the presence of telomeric sequences. Taken together, our data show that ITS themselves do not enhance the formation of radiation-induced chromosome rearrangements in these human cell lines. Copyright 2003 S. Karger AG, Basel

The best time for surgery on a patient with recurrent pneumothorax and undetectable culprit lesions is at the exact time air leakage is discovered: a case report.

PubMed

Matsumoto, Yousuke; Hata, Yoshinobu; Makino, Takashi; Koezuka, Satoshi; Otsuka, Hajime; Sugino, Keishi; Isobe, Kazutoshi; Homma, Sakae; Iyoda, Akira

2016-08-02

One cause of recurrent spontaneous pneumothorax includes overlooking bullae during a previous surgery for pneumothorax; and the identification of the culprit lesions is necessary for prevention of recurrence. A 28-year-old man was referred to our hospital because of spontaneous right-sided pneumothorax. He underwent video-assisted thoracoscopic surgery, which did not reveal air leakage. The patient was subsequently seen at our hospital for 2 additional episodes of recurrent right-sided pneumothorax. At the third admission we observed intermittent air leakage while the patient was in the sitting position after chest drainage, and we performed surgery. An intraoperative submersion test showed air leakage dorsally from the pleural surface of S(6) and a minute culprit lesion, which were not seen at the first operation and confirmed the leakage site. The area was ligated and coated with regenerated oxidized cellulose mesh and autologous blood. In cases of pneumothorax with repeated recurrence, the best time to perform surgery on the patient with undetectable culprit lesion is the exact time that air leakage is observed.

The influence of cultural factors on obsessive compulsive disorder: religious symptoms in a religious society.

PubMed

Greenberg, D; Witztum, E

1994-01-01

Judaism is one of many religions that demand cleanliness and exactness, inculcate the performance of rituals from childhood and view their non-performance as wrong or sinful. Rituals concerning cleanliness and exactness are the commonest presentations of OCD. In a sample of 34 psychiatric out-patients with OCD in north Jerusalem, religious symptoms were found in 13 of the 19 ultra-orthodox patients, and in one of the 15 non-ultra-orthodox patients. Nine of the 15 OCD patients with religious symptoms also had non-religious symptoms. Four main topics of religious symptomatology were found: prayer, dietary practices, menstrual practices and cleanliness before prayer. The dictates of religious codes regarding these topics are presented and the law is rigorous in its demands, in many cases encouraging repeating rituals. Nevertheless, repetitive performance of religious rituals is recognized by OCD sufferers and their rabbis as expressing psychopathology rather than heightened spirituality. The forms of the religious obsessions and the associated rituals in this sample were similar to the presentation of OCD in non-religious patients. Religion appears not to be a distinctive topic of OCD, rather it is the setting for the condition in very religious patients.

On the seismic response of instable rock slopes based on ambient vibration recordings

NASA Astrophysics Data System (ADS)

Kleinbrod, Ulrike; Burjánek, Jan; Fäh, Donat

2017-09-01

Rock slope failures can lead to huge human and economic loss depending on their size and exact location. Reasonable hazard mitigation requires thorough understanding of the underlying slope driving mechanisms and its rock mass properties. Measurements of seismic ambient vibrations could improve the characterization and detection of rock instabilities since there is a link between seismic response and internal structure of the unstable rock mass. An unstable slope near the village Gondo has been investigated. The unstable part shows strongly amplified ground motion with respect to the stable part of the rock slope. The amplification values reach maximum factors of 70. The seismic response on the instable part is highly directional and polarized. Re-measurements have been taken 1 year later showing exactly the same results as the original measurements. Neither the amplified frequencies nor the amplification values have changed. Therefore, ambient vibration measurements are repeatable and stay the same, if the rock mass has not undergone any significant change in structure or volume, respectively. Additionally, four new points have been measured during the re-measuring campaign in order to better map the border of the instability.[Figure not available: see fulltext.

Impact of uncertainties in free stream conditions on the aerodynamics of a rectangular cylinder

NASA Astrophysics Data System (ADS)

Mariotti, Alessandro; Shoeibi Omrani, Pejman; Witteveen, Jeroen; Salvetti, Maria Vittoria

2015-11-01

The BARC benchmark deals with the flow around a rectangular cylinder with chord-to-depth ratio equal to 5. This flow configuration is of practical interest for civil and industrial structures and it is characterized by massively separated flow and unsteadiness. In a recent review of BARC results, significant dispersion was observed both in experimental and numerical predictions of some flow quantities, which are extremely sensitive to various uncertainties, which may be present in experiments and simulations. Besides modeling and numerical errors, in simulations it is difficult to exactly reproduce the experimental conditions due to uncertainties in the set-up parameters, which sometimes cannot be exactly controlled or characterized. Probabilistic methods and URANS simulations are used to investigate the impact of the uncertainties in the following set-up parameters: the angle of incidence, the free stream longitudinal turbulence intensity and length scale. Stochastic collocation is employed to perform the probabilistic propagation of the uncertainty. The discretization and modeling errors are estimated by repeating the same analysis for different grids and turbulence models. The results obtained for different assumed PDF of the set-up parameters are also compared.

Laser-powered Martian rover

NASA Technical Reports Server (NTRS)

Harries, W. L.; Meador, W. E.; Miner, G. A.; Schuster, Gregory L.; Walker, G. H.; Williams, M. D.

1989-01-01

Two rover concepts were considered: an unpressurized skeleton vehicle having available 4.5 kW of electrical power and limited to a range of about 10 km from a temporary Martian base and a much larger surface exploration vehicle (SEV) operating on a maximum 75-kW power level and essentially unrestricted in range or mission. The only baseline reference system was a battery-operated skeleton vehicle with very limited mission capability and range and which would repeatedly return to its temporary base for battery recharging. It was quickly concluded that laser powering would be an uneconomical overkill for this concept. The SEV, on the other hand, is a new rover concept that is especially suited for powering by orbiting solar or electrically pumped lasers. Such vehicles are visualized as mobile habitats with full life-support systems onboard, having unlimited range over the Martian surface, and having extensive mission capability (e.g., core drilling and sampling, construction of shelters for protection from solar flares and dust storms, etc.). Laser power beaming to SEV's was shown to have the following advantages: (1) continuous energy supply by three orbiting lasers at 2000 km (no storage requirements as during Martian night with direct solar powering); (2) long-term supply without replacement; (3) very high power available (MW level possible); and (4) greatly enhanced mission enabling capability beyond anything currently conceived.

Laser-powered Martian rover

NASA Astrophysics Data System (ADS)

Harries, W. L.; Meador, W. E.; Miner, G. A.; Schuster, Gregory L.; Walker, G. H.; Williams, M. D.

1989-07-01

Two rover concepts were considered: an unpressurized skeleton vehicle having available 4.5 kW of electrical power and limited to a range of about 10 km from a temporary Martian base and a much larger surface exploration vehicle (SEV) operating on a maximum 75-kW power level and essentially unrestricted in range or mission. The only baseline reference system was a battery-operated skeleton vehicle with very limited mission capability and range and which would repeatedly return to its temporary base for battery recharging. It was quickly concluded that laser powering would be an uneconomical overkill for this concept. The SEV, on the other hand, is a new rover concept that is especially suited for powering by orbiting solar or electrically pumped lasers. Such vehicles are visualized as mobile habitats with full life-support systems onboard, having unlimited range over the Martian surface, and having extensive mission capability (e.g., core drilling and sampling, construction of shelters for protection from solar flares and dust storms, etc.). Laser power beaming to SEV's was shown to have the following advantages: (1) continuous energy supply by three orbiting lasers at 2000 km (no storage requirements as during Martian night with direct solar powering); (2) long-term supply without replacement; (3) very high power available (MW level possible); and (4) greatly enhanced mission enabling capability beyond anything currently conceived.

The comparability of the universalism value over time and across countries in the European Social Survey: exact vs. approximate measurement invariance

PubMed Central

Zercher, Florian; Schmidt, Peter; Cieciuch, Jan; Davidov, Eldad

2015-01-01

Over the last decades, large international datasets such as the European Social Survey (ESS), the European Value Study (EVS) and the World Value Survey (WVS) have been collected to compare value means over multiple time points and across many countries. Yet analyzing comparative survey data requires the fulfillment of specific assumptions, i.e., that these values are comparable over time and across countries. Given the large number of groups that can be compared in repeated cross-national datasets, establishing measurement invariance has been, however, considered unrealistic. Indeed, studies which did assess it often failed to establish higher levels of invariance such as scalar invariance. In this paper we first introduce the newly developed approximate approach based on Bayesian structural equation modeling (BSEM) to assess cross-group invariance over countries and time points and contrast the findings with the results from the traditional exact measurement invariance test. BSEM examines whether measurement parameters are approximately (rather than exactly) invariant. We apply BSEM to a subset of items measuring the universalism value from the Portrait Values Questionnaire (PVQ) in the ESS. The invariance of this value is tested simultaneously across 15 ESS countries over six ESS rounds with 173,071 respondents and 90 groups in total. Whereas, the use of the traditional approach only legitimates the comparison of latent means of 37 groups, the Bayesian procedure allows the latent mean comparison of 73 groups. Thus, our empirical application demonstrates for the first time the BSEM test procedure on a particularly large set of groups. PMID:26089811

Characterization of a Planet: Dependence on Coverage Fraction

NASA Astrophysics Data System (ADS)

Lorenz, R. D.

1996-03-01

I investigate, by means of numerical experiments and a real-time quiz of colleagues (to be repeated at the poster presentation associated with this abstract), how well-characterized a planet may be considered, as a function of how much of its surface has been studied. Most measures seem to indicate that characterization quality increases steeply up to about 30% coverage. Beyond 30%, additional coverage has a lower marginal value as a 'complete' knowledge of the surface is asymptotically reached. These studies are pertinent where tradeoffs of coverage against other scientific objectives exist, for example the orbital tour design of the Cassini mission. The tour design affects how much of Titan's surface (after the Galileo mission, Titan's surface becomes the largest mappable, but unmapped, area in the solar system) may be covered by the Cassini radar. The mission has too few flybys to cover all of Titan's surface: the Radar team aims to have 30% coverage at 1km resolution or better. I also find that long, thin swaths sample a planet better than square blocks of equivalent area.

Spacelab

NASA Image and Video Library

1981-01-01

The primary purpose of the Spacelab-3 mission was to conduct materials science experiments in a stable low-gravity environment. In addition, the crew did research in life sciences, fluid mechanics, atmospheric science, and astronomy. Spacelab-3 was equipped with several new mini-labs, special facilities that would be used repeatedly on future flights. Two elaborate crystal growth furnaces, a life support and housing facility for small animals, and two types of apparatus for the study of fluids were evaluated on their inaugural flight. The instruments requiring direct exposure to space were mounted outside in the open payload bay of the Shuttle. Spacelab represented the merger of science and marned spaceflight. It opened remarkable opportunities to push the frontiers of knowledge beyond the limits of research on Earth. Scientists in space performed experiments in close collaboration with their colleagues on the ground. On the Spacelab-3 mission, managed by the Marshall Space Flight Center, this versatile laboratory entered routine operation service for the next two decades. Spacelab-3 (STS-51B mission) was launched aboard Space Shuttle Orbiter Challenger on April 29, 1985.

Persistence of Space Radiation-Induced Cytogenetic Damage in the Blood Lymphocytes of Astronauts and the Effects of Repeat Long Duration Space Missions

NASA Technical Reports Server (NTRS)

George, Kerry A.; Cucinotta, Francis A.

2009-01-01

The yield of chromosome damage in astronauts blood lymphocytes has been shown to increase after long duration space missions of a few months or more. This provides a useful in vivo measurement of space radiation induced damage that takes into account individual radiosensitivity and considers the influence of microgravity and other stress conditions. We present our latest follow-up analyses of chromosome damage in astronauts blood lymphocytes assessed by fluorescence in situ hybridization (FISH) chromosome painting and collected at various times, from directly after return from space to several years after flight. For most individuals the analysis of individual time-courses for translocations revealed a temporal decline of yields with different half-lives. Dose was derived from frequencies of chromosome exchanges using preflight calibration curves, and estimates derived from samples collected a few days after return to earth lie within the range expected from physical dosimetry. However, a temporal decline in yields may indicate complications with the use of stable aberrations for retrospective dose reconstruction, and the differences in the decay time may reflect individual variability in risk from space radiation exposure. Limited data on three individuals who have participated in repeat long duration space flights indicates a lack of correlation between time in space and translocation yields, and show a possible adaptive response to space radiation exposure.

Observations and Mitigation of RFI in ALOS PALSAR SAR Data; Implications for the Desdyni Mission

NASA Technical Reports Server (NTRS)

Rosen, Paul A.; Hensley, Scott; Le, Charles

2008-01-01

Initial examination of ALOS PALSAR synthetic aperture radar (SAR) data has indicated significant radio frequency interference (RFI) in several geographic locations around the world. RFI causes significant reduction in image contrast, introduces periodic and quasi-periodic image artifacts, and introduces significant phase noise in repeat pass interferometric data reduction. The US National Research Council Decadal Survey of Earth Science has recommended DESDynI, a Deformation, Ecosystems, and Dynamics of Ice satellite mission comprising an L-band polarimetric radar configured for repeat pass interferometry. There is considerable interest internationally in other future L-band and lower frequency systems as well. Therefore the issues of prevalence and possibilities of mitigation of RFI in these crowded frequency bands is of considerable interest. RFI is observed in ALOS PALSAR in California, USA, and in southern Egypt in data examined to date. Application of several techniques for removing it from the data prior to SAR image formation, ranging from straightforward spectral normalization to time-domain, multi-phase filtering techniques are considered. Considerable experience has been gained from the removal of RFI from P-band acquired by the GeoSAR system. These techniques applied to the PALSAR data are most successful when the bandwidth of any particular spectral component of the RFI is narrow. Performance impacts for SAR imagery and interferograms are considered in the context of DESDynI measurement requirements.

Analysis of 100-lb(sub f) (445-N) LO2-LCH4 Reaction Control Engine Impulse Bit Performance

NASA Technical Reports Server (NTRS)

Marshall, William M.; Klenhenz, Julie E.

2012-01-01

Recently, liquid oxygen-liquid methane (LO2-LCH4) has been considered as a potential green propellant alternative for future exploration missions. The Propulsion and Cryogenic Advanced Development (PCAD) project was tasked by NASA to develop this propulsion combination to enable safe and cost-effective exploration missions. To date, limited experience with such combinations exist, and as a result a comprehensive test program is critical to demonstrating with the viability of implementing such a system. The NASA Glenn Research Center conducted a test program of a 100-lbf (445-N) reaction control engine (RCE) at the Center s Altitude Combustion Stand (ACS), focusing on altitude testing over a wide variety of operational conditions. The ACS facility includes unique propellant conditioning feed systems (PCFS), which allow precise control of propellant inlet conditions to the engine. Engine performance as a result of these inlet conditions was examined extensively during the test program. This paper is a companion to the previous specific impulse testing paper, and discusses the pulsed-mode operation portion of testing, with a focus on minimum impulse bit (MIB) and repeatable pulse performance. The engine successfully demonstrated target MIB performance at all conditions, as well as successful demonstration of repeatable pulse widths. Some anomalous conditions experienced during testing are also discussed, including a double pulse phenomenon, which was not noted in previous test programs for this engine.

Flora: A Proposed Hyperspectral Mission

NASA Technical Reports Server (NTRS)

Ungar, Stephen; Asner, Gregory; Green, Robert; Knox, Robert

2006-01-01

In early 2004, one of the authors (Stephen Ungar, NASA GSFC) presented a mission concept called "Spectrasat" at the AVIRIS Workshop in Pasadena, CA. This mission concept grew out of the lessons learned from the Earth Observing-One (EO-1) Hyperion Imaging Spectrometer and was structured to more effectively accomplish the types of studies conducted with Hyperion. The Spectrasat concept represented an evolution of the technologies and operation strategies employed on EO-I. The Spectrasat concept had been preceded by two community-based missions proposed by Susan Ustin, UC Davis and Robert Green, NASA JPL. As a result of community participation, starting at this AVIRIS Workshop, the Spectrasat proposal evolved into the Flora concept which now represents the combined visions of Gregory Asner (Carnegie Institute), Stephen Ungar, Robert Green and Robert Knox, NASA GSFC. Flora is a proposed imaging spectrometer mission, designed to address global carbon cycle science issues. This mission centers on measuring ecological disturbance for purposes of ascertaining changes in global carbon stocks and draws heavily on experience gained through AVIRIS airborne flights and Hyperion space born flights. The observing strategy exploits the improved ability of imaging spectrometers, as compared with multi-spectral observing systems, to identify vegetation functional groups, detect ecosystem response to disturbance and assess the related discovery. Flora will be placed in a sun synchronous orbit, with a 45 meter pixel size, a 90 km swath width and a 31 day repeat cycle. It covers the spectral range from 0.4 to 2.5 micrometers with a spectral sampling interval of 10 nm. These specifications meet the needs of the Flora science team under the leadership of Gregory Asner. Robert Green, has introduced a spectrometer design for Flora which is expected to have a SNR of 600: 1 in the VNIR and 450: 1 in the SWIR. The mission team at NASA GSFC is designing an Intelligent Payload Module (IPM) designed to effectively reduce the volume of data required to be transmitted down to the ground. This paper discusses mission science objectives, describes the mission concept and presents the current status of possible funding opportunities leading to realization of the mission.

The street children of Manila are affected by early-in-life periodontal infection: description of a treatment modality: sea salt.

PubMed

Michel, J F; Michel, M G; Nadan, J; Nowzari, H

2013-01-01

Thousands of street children of Manila are affected by early-in-life oral infection. The aim of the present investigation was to evaluate the effectiveness of a sea-salt mouthrinse solution in street children of Manila affected by mild to severe forms of periodontal disease. These children were all in need of special protection: abandoned, abused, exploited, neglected, orphaned, poor. During 3 oral-health missions in 2003, 2004 and 2005, 617 abandoned children (5 to 13 year-old), received oral examination at a non-sectarian child-caring institution in Metro Manila (Virlanie Foundation) by calibrated examiners. A treatment based on what could be done was proposed: 1. Teaching of a precise tooth brushing technique with sea-salt, controlled and reinforced every two days for one week by calibrated health educators, 2. The application of sea-salt water mouthrinse (2.5 gram in 20 ml). Periodontal measurements were repeated at the end of each mission. All children returned to child-caring institution for the followup examinations. In 2003, 10 male and 11 female (n=21) were diagnosed with aggressive periodontitis. In 2009 and 2010, none was affected by aggressive periodontitis. For all patients, the gingival index decreased from 1.08 at the first mission to 1.04 at the end of the second mission and 0.98 at the end of the third mission. The periodontal index decreased from 1.33 at the first mission to 0.98 at the second mission and 0.92 at the last mission. The present investigation confirms that prevention and early diagnosis can result in success with minimum cost. The provided oral health program empowered street children in the most desperate circumstances to be educated and become self-reliant, independent, and responsible. We propose here an antimicrobial approach which has a high degree of efficacy and tolerability, and can be implemented in virtually all parts of the world using low-cost resources.

Structural DNA nanotechnology: from design to applications.

PubMed

Zadegan, Reza M; Norton, Michael L

2012-01-01

The exploitation of DNA for the production of nanoscale architectures presents a young yet paradigm breaking approach, which addresses many of the barriers to the self-assembly of small molecules into highly-ordered nanostructures via construct addressability. There are two major methods to construct DNA nanostructures, and in the current review we will discuss the principles and some examples of applications of both the tile-based and DNA origami methods. The tile-based approach is an older method that provides a good tool to construct small and simple structures, usually with multiply repeated domains. In contrast, the origami method, at this time, would appear to be more appropriate for the construction of bigger, more sophisticated and exactly defined structures.

Game-like tasks for comparative research: leveling the playing field

NASA Technical Reports Server (NTRS)

Washburn, D. A.; Gulledge, J. P.; Rumbaugh, D. M. (Principal Investigator)

1995-01-01

Game-like computer tasks offer many benefits for psychological research. In this paper, the usefulness of such tasks to bridge population differences (e.g., age, intelligence, species) is discussed and illustrated. A task called ALVIN was used to assess humans' and monkeys' working memory for sequences of colors with or without tones. Humans repeated longer lists than did the monkeys, and only humans benefited when the visual stimuli were accompanied by auditory cues. However, the monkeys did recall sequences at levels comparable to those reported elsewhere for children. Comparison of similarities and differences between the species is possible because the two groups were tested with exactly the same game-like paradigm.

Simplicity and efficiency of integrate-and-fire neuron models.

PubMed

Plesser, Hans E; Diesmann, Markus

2009-02-01

Lovelace and Cios (2008) recently proposed a very simple spiking neuron (VSSN) model for simulations of large neuronal networks as an efficient replacement for the integrate-and-fire neuron model. We argue that the VSSN model falls behind key advances in neuronal network modeling over the past 20 years, in particular, techniques that permit simulators to compute the state of the neuron without repeated summation over the history of input spikes and to integrate the subthreshold dynamics exactly. State-of-the-art solvers for networks of integrate-and-fire model neurons are substantially more efficient than the VSSN simulator and allow routine simulations of networks of some 10(5) neurons and 10(9) connections on moderate computer clusters.

Phase retrieval based wavefront sensing experimental implementation and wavefront sensing accuracy calibration

NASA Astrophysics Data System (ADS)

Mao, Heng; Wang, Xiao; Zhao, Dazun

2009-05-01

As a wavefront sensing (WFS) tool, Baseline algorithm, which is classified as the iterative-transform algorithm of phase retrieval, estimates the phase distribution at pupil from some known PSFs at defocus planes. By using multiple phase diversities and appropriate phase unwrapping methods, this algorithm can accomplish reliable unique solution and high dynamic phase measurement. In the paper, a Baseline algorithm based wavefront sensing experiment with modification of phase unwrapping has been implemented, and corresponding Graphical User Interfaces (GUI) software has also been given. The adaptability and repeatability of Baseline algorithm have been validated in experiments. Moreover, referring to the ZYGO interferometric results, the WFS accuracy of this algorithm has been exactly calibrated.

Game-like tasks for comparative research: leveling the playing field.

PubMed

Washburn, D A; Gulledge, J P

1995-01-01

Game-like computer tasks offer many benefits for psychological research. In this paper, the usefulness of such tasks to bridge population differences (e.g., age, intelligence, species) is discussed and illustrated. A task called ALVIN was used to assess humans' and monkeys' working memory for sequences of colors with or without tones. Humans repeated longer lists than did the monkeys, and only humans benefited when the visual stimuli were accompanied by auditory cues. However, the monkeys did recall sequences at levels comparable to those reported elsewhere for children. Comparison of similarities and differences between the species is possible because the two groups were tested with exactly the same game-like paradigm.

Van Allen Probes Science Gateway and Space Weather Data Processing

NASA Astrophysics Data System (ADS)

Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

2014-12-01

The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

Simplified Phased-Mission System Analysis for Systems with Independent Component Repairs

NASA Technical Reports Server (NTRS)

Somani, Arun K.

1996-01-01

Accurate analysis of reliability of system requires that it accounts for all major variations in system's operation. Most reliability analyses assume that the system configuration, success criteria, and component behavior remain the same. However, multiple phases are natural. We present a new computationally efficient technique for analysis of phased-mission systems where the operational states of a system can be described by combinations of components states (such as fault trees or assertions). Moreover, individual components may be repaired, if failed, as part of system operation but repairs are independent of the system state. For repairable systems Markov analysis techniques are used but they suffer from state space explosion. That limits the size of system that can be analyzed and it is expensive in computation. We avoid the state space explosion. The phase algebra is used to account for the effects of variable configurations, repairs, and success criteria from phase to phase. Our technique yields exact (as opposed to approximate) results. We demonstrate our technique by means of several examples and present numerical results to show the effects of phases and repairs on the system reliability/availability.

Neural Network Based Sensory Fusion for Landmark Detection

NASA Technical Reports Server (NTRS)

Kumbla, Kishan -K.; Akbarzadeh, Mohammad R.

1997-01-01

NASA is planning to send numerous unmanned planetary missions to explore the space. This requires autonomous robotic vehicles which can navigate in an unstructured, unknown, and uncertain environment. Landmark based navigation is a new area of research which differs from the traditional goal-oriented navigation, where a mobile robot starts from an initial point and reaches a destination in accordance with a pre-planned path. The landmark based navigation has the advantage of allowing the robot to find its way without communication with the mission control station and without exact knowledge of its coordinates. Current algorithms based on landmark navigation however pose several constraints. First, they require large memories to store the images. Second, the task of comparing the images using traditional methods is computationally intensive and consequently real-time implementation is difficult. The method proposed here consists of three stages, First stage utilizes a heuristic-based algorithm to identify significant objects. The second stage utilizes a neural network (NN) to efficiently classify images of the identified objects. The third stage combines distance information with the classification results of neural networks for efficient and intelligent navigation.

KSC-08pd0008

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, the first two of nine pins have been soldered to the socket of the replacement feed-through connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. Two United Launch Alliance technicians, who performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994, will be doing the soldering. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0007

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, the first two of nine pins have been soldered to the socket of the replacement feed-through connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. Two United Launch Alliance technicians, who performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994, will be doing the soldering. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

Reconnaissance Of The Year 2000 And Beyond

NASA Astrophysics Data System (ADS)

Dresser, M. M.

1981-12-01

The reconnaissance systems of the year 2000 and beyond may be merely an extension of current technology or may utilize bold new technology and concepts still in the embryonic stages. The five basic reconnaissance mission stages: collection, processing, interpretation, reporting, and dissemination, are reviewed in terms of the potential application of new and emerging technology such as high density multispectral focal plane arrays, new radar techniques, VLSI/VHSIC computational resources, artificial intelligence, multisensor integration, pattern and target recognition, image compression, advanced display and targeting techniques, and even new fields not thought of as exact sciences today. The application of these technologies is viewed in the context of the reconnaissance missions: targeting, damage assessment, order of battle assessment, terrain evaluation and planning. The traditional neeos for varying levels of detail and timeliness of reconnaissance data are shown to be largely removed by the use of the most advanced and highest development risk systems. Lower development risk systems show excellent capabilities with the potential for high capability at low cost. New fields may totally change or even eliminate reconnaissance as we know it today.

The Ice, Cloud, and Land Elevation Satellite-2 (ICESat-2): Science Requirements, Concept, and Implementation

NASA Technical Reports Server (NTRS)

Markus, Thorsten; Neumann, Tom; Martino, Anthony; Abdalati, Waleed; Brunt, Kelly; Csatho, Beata; Farrell, Sinead; Fricker, Helen; Gardner, Alex; Harding, David;

Determination of the Beagle2 landing site

NASA Astrophysics Data System (ADS)

Trautner, R.; Manaud, N.; Michael, G.; Griffiths, A.; Beauvivre, S.; Koschny, D.; Coates, A.; Josset, J.-L.

2004-02-01

Beagle2 is the UK-led lander element on ESA's Mars Express mission, which will reach Mars in late December 2003. After separation from the Mars Express orbiter 6 days before the atmospheric entry, Beagle2 will descend to the Martian surface by means of ablative heat shields and parachutes. The impact will be cushioned by a set of airbags. The selected landing site at 11.6 deg N/90.75 deg E (IAU 2000 coordinates) is situated in the south-east of the center of Isidis Planitia, a sedimentary basin which is expected to meet the requirements of Beagle's scientific mission, the lander operations, and the entry, descent and landing systems. The exact determination of the Beagle2 landing site is important not only for the Beagle2 and MEX orbiter science investigations, but also for the reconstruction of Beagle's entry and descent trajectory. A precise determination of the Beagle2 position is not possible via the MELACOM radio link. Instead, a novel method based on celestial navigation is employed, which utilizes the Stereo Camera System on the lander for imaging the Martian night sky. The position data is then refined by comparing the landing site panorama images with high resolution orbiter images and laser altimeter data. This combination of celestial navigation with image data analysis for precision position determination will be applicable for many future missions as well.

The Effect of Transcranial Direct Current Stimulation (tDCS) Electrode Size and Current Intensity on Motor Cortical Excitability: Evidence From Single and Repeated Sessions.

PubMed

Ho, Kerrie-Anne; Taylor, Janet L; Chew, Taariq; Gálvez, Verònica; Alonzo, Angelo; Bai, Siwei; Dokos, Socrates; Loo, Colleen K

2016-01-01

Current density is considered an important factor in determining the outcomes of tDCS, and is determined by the current intensity and electrode size. Previous studies examining the effect of these parameters on motor cortical excitability with small sample sizes reported mixed results. This study examined the effect of current intensity (1 mA, 2 mA) and electrode size (16 cm(2), 35 cm(2)) on motor cortical excitability over single and repeated tDCS sessions. Data from seven studies in 89 healthy participants were pooled for analysis. Single-session data were analyzed using mixed effects models and repeated-session data were analyzed using mixed design analyses of variance. Computational modeling was used to examine the electric field generated. The magnitude of increases in excitability after anodal tDCS was modest. For single-session tDCS, the 35 cm(2) electrodes produced greater increases in cortical excitability compared to the 16 cm(2) electrodes. There were no differences in the magnitude of cortical excitation produced by 1 mA and 2 mA tDCS. The repeated-sessions data also showed that there were greater increases in excitability with the 35 cm(2) electrodes. Further, repeated sessions of tDCS with the 35 cm(2) electrodes resulted in a cumulative increase in cortical excitability. Computational modeling predicted higher electric field at the motor hotspot for the 35 cm(2) electrodes. 2 mA tDCS does not necessarily produce larger effects than 1 mA tDCS in healthy participants. Careful consideration should be given to the exact positioning, size and orientation of tDCS electrodes relative to cortical regions. Copyright © 2016 Elsevier Inc. All rights reserved.

Micro-satellite constellations for monitoring cryospheric processes and related natural hazards

NASA Astrophysics Data System (ADS)

Kaeaeb, A.; Altena, B.; Mascaro, J.

2016-12-01

Currently, several micro-satellite constellations for earth-observation are planned or under build-up. Here, we assess the potential of the well-advanced Planet satellite constellation for investigating cryospheric processes. In its final stage, the Planet constellation will consist of 150 free-flying micro-satellites in near-polar and ISS orbits. The instruments carry RGB+NIR frame cameras that image the Earth surface in nadir direction with resolutions of 3-5 m, covering 20 x 13 km per image. In its final set-up, the constellation will be able to image the (almost) entire land surface at least once per day, under the limitation of cloud cover. Here, we explore new possibilities for insight into cryospheric processes that this very high repeat cycle combined with high image resolution offer. Based on repeat Planet imagery we derive repeat glacier velocity fields for example glaciers in the northern and southern hemispheres. We find it especially useful to monitor the ice velocities near calving fronts and simultaneously detect changes of the front, pointing to calving events. We also explore deformation fields over creeping mountain permafrost, so-called rockglaciers. As a second, very promising cryospheric application we suggest monitoring of glacier and permafrost related natural hazards. In cases such as temporary lakes, lake outbursts, landslides, rock avalanches, visual information over remote areas and at high frequencies are crucial for hazard assessment, early warning or disaster management. Based on several examples, we demonstrate that massive micro-satellite constellations such Planet's are exactly able to provide this type of information. As a third promising example, we show how such high-repeat optical satellite data are useful to monitor river ice and related jams and flooding. At certain latitudes, the repeat frequency of the data is even high enough to track river ice floes and thus water velocities.

Laboratory validation of a new gas-enhanced dentine liquid permeation evaluation system.

PubMed

Al-Jadaa, Anas; Attin, Thomas; Peltomäki, Timo; Heumann, Christian; Schmidlin, Patrick R

2014-12-01

To validate a new automated dentine permeability testing platform based on pressure change measurements. A split chamber was designed allowing for concomitant measurement of fluid permeation and pressure difference. In a first test, system reliability was assessed by interposing a solid metal disk, embedded composite resin disks, or teeth by consecutively measuring eight times under standardized conditions. Secondly, the repeatability and applicability of the method was tested in a dentine wound model by using intact third molars: Class I (2 × 5 mm) and a full occlusal preparation as well a ceramic restoration were consecutively performed and repeatedly measured eight times each. In the last test, the system detection limit as well correlation between gas pressure difference and liquid permeation were evaluated: Again, third molars were used and occlusal preparations of increasing size (2 × 5, 3 × 5, 4 × 5, and 5 × 5 mm and full occlusal preparations, respectively) were made. Data was analyzed for the linearity of measurement, and R (2) values were calculated. The embedding procedure allowed for perfect separation of the two chambers, and no significant variation in repeated measurements of evaluated samples for the respective treatments (p = 0.05) was found. The detection was 0.002 hPa/min for the pressure slope and 0.0225 μl/min for the fluid infiltration, respectively. The saline volume was highly correlating to the gas pressure changes (R (2) = 0.996, p < 0.0001). The presented method is a reliable and exact tool to assess dentine permeability by nondestructive and repeatable measurements. This method is suitable for measurements and comparison of the effectiveness of dentine wounds sealing materials.

The Space Station Prototype Program - The development of a regenerative life support system for extended-duration missions.

NASA Technical Reports Server (NTRS)

Willis, N. C., Jr.; Neel, J. M.

1972-01-01

Design concepts and test philosophies which may contribute to the development of a low-cost maintainable environmental control/life support system are examined. It is shown that the concept of producing flight prototype equipment during a developmental program can reduce the eventual cost of a flight system by incorporating realistic flight-type design requirements without imposing exacting design features and stringent controls. A flight prototype design is one that can be converted readily into an actual flight design without any conceptual change. Modularity of subsystems provides the system and the program a degree of flexibility relative to the eventual vehicle configuration and technological improvements.

Space Tug avionics definition study. Volume 2: Avionics functional requirements

NASA Technical Reports Server (NTRS)

1975-01-01

Flight and ground operational phases of the tug/shuttle system are analyzed to determine the general avionics support functions that are needed during each of the mission phases and sub-phases. Each of these general support functions is then expanded into specific avionics system requirements, which are then allocated to the appropriate avionics subsystems. This process is then repeated at the next lower level of detail where these subsystem requirements are allocated to each of the major components that comprise a subsystem.

Atmospheric electricity criteria guidelines for use in aerospace vehicle development

NASA Technical Reports Server (NTRS)

Daniels, G. E.

1972-01-01

Lightning has always been of concern for aerospace vehicle ground activities. The unexpected triggering of lightning discharges by the Apollo 12 space vehicle shortly after launch and the more recent repeated lightning strikes to the launch umbilical tower while the Apollo 15 space vehicle was being readied for launch have renewed interest in studies of atmospheric electricity as it relates to space vehicle missions. The material presented reflects some of the results of these studies with regard to updating the current criteria guidelines.

Soviet-Warsaw Pact Western Theater of Military Operations: Organization and Missions.

DTIC Science & Technology

1987-08-01

Khabarovsk Border Troops Gen A Gerasino Transbaykal Border Group Gen I Zaytsev District I Troops Dist Primorskiy Border Troops Amur Natl*Gen A Afanas’yev...while Dutch and German Leopards battled T-72s. In the air, F-15s and F-16s would fight various MiGs. The U.S. technological advantage in electronics...achieved along the Amur River in 1945 could not be repeated on the Rhine. 5See Velikaya otechestvennaya voyna Sovetskogo soyuza (The Great Patriotic

Micro-XRF : Elemental Analysis for In Situ Geology and Astrobiology Exploration

NASA Technical Reports Server (NTRS)

Allwood, Abigail; Hodyss, Robert; Wade, Lawrence

2012-01-01

The ability to make close-up measurements of rock chemistry is one of the most fundamental tools for astrobiological exploration of Mars and other rocky bodies of the solar system. When conducting surface-based exploration, lithochemical measurements provide critical data that enable interpretation of the local geology, which in turn is vital for determining habitability and searching for evidence of life. The value of lithochemical measurements for geological interpretations has been repeatedly demonstrated with virtually every landed Mars mission over the past four decades.

Space Mission Operations Ground Systems Integration Customer Service

NASA Technical Reports Server (NTRS)

Roth, Karl

2014-01-01

The facility, which is now the Huntsville Operations Support Center (HOSC) at Marshall Space Flight Center in Huntsville, AL, has provided continuous space mission and related services for the space industry since 1961, from Mercury Redstone through the International Space Station (ISS). Throughout the long history of the facility and mission support teams, the HOSC has developed a stellar customer support and service process. In this era, of cost cutting, and providing more capability and results with fewer resources, space missions are looking for the most efficient way to accomplish their objectives. One of the first services provided by the facility was fax transmission of documents to, then, Cape Canaveral in Florida. The headline in the Marshall Star, the newspaper for the newly formed Marshall Space Flight Center, read "Exact copies of Documents sent to Cape in 4 minutes." The customer was Dr. Wernher von Braun. Currently at the HOSC we are supporting, or have recently supported, missions ranging from simple ISS payloads requiring little more than "bentpipe" telemetry access, to a low cost free-flyer Fast, Affordable, Science and Technology Satellite (FASTSAT), to a full service ISS payload Alpha Magnetic Spectrometer 2 (AMS2) supporting 24/7 operations at three operations centers around the world with an investment of over 2 billion dollars. The HOSC has more need and desire than ever to provide fast and efficient customer service to support these missions. Here we will outline how our customer-centric service approach reduces the cost of providing services, makes it faster and easier than ever for new customers to get started with HOSC services, and show what the future holds for our space mission operations customers. We will discuss our philosophy concerning our responsibility and accessibility to a mission customer as well as how we deal with the following issues: initial contact with a customer, reducing customer cost, changing regulations and security, and cultural differences, to ensure an efficient response to customer issues using a small Customer Service Team (CST) and adaptability, constant communication with customers, technical expertise and knowledge of services, and dedication to customer service. The HOSC Customer Support Team has implemented a variety of processes, and procedures that help to mitigate the potential problems that arise when integrating ground system services for a variety of complex missions and the lessons learned from this experience will lead the future of customer service in the space operations industry.

Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression.

PubMed

Plaschke, Jens; Krüger, Stefan; Jeske, Birgit; Theissig, Franz; Kreuz, Friedmar R; Pistorius, Steffen; Saeger, Hans D; Iaccarino, Ingram; Marra, Giancarlo; Schackert, Hans K

2004-02-01

Mononucleotide repeat sequences are particularly prone to frameshift mutations in tumors with biallelic inactivation of the mismatch repair (MMR) genes MLH1 or MSH2. In these tumors, several genes harboring mononucleotide repeats in their coding region have been proposed as targets involved in tumor progression, among which are also the MMR genes MSH3 and MSH6. We have analyzed the expression of the MSH3 and MSH6 proteins by immunohistochemistry in 31 colorectal carcinomas in which MLH1 was inactivated. Loss of MSH3 expression was identified in 15 tumors (48.5%), whereas all tumors expressed MSH6. Frameshift mutations at coding microsatellites were more frequent in MSH3 (16 of 31) than in MSH6 (3 of 31; Fisher's exact test, P < 0.001). Frameshift mutations and allelic losses of MSH3 were more frequent in MSH3-negative tumors compared with those with normal expression (22 mutations in 30 alleles versus 8 mutations in 28 alleles; chi(2), P = 0.001). Biallelic inactivation was evident or inferred for 60% of MSH3-negative tumors but none of the tumors with normal MSH3 expression. In contrast, we did not identify frameshift mutations in the (A)8 tract of MSH3 in a control group of 18 colorectal carcinomas in which the MMR deficiency was based on the inactivation of MSH2. As it has been suggested that mutations of MSH3 might play a role in tumor progression, we studied the association between MSH3 expression and disease stage assessed by lymph node and distant metastases status. Dukes stages C and D were more frequent in primary tumors with loss of MSH3 expression (9 of 13), compared with tumors with retained expression (1 of 14; Fisher's exact test, P = 0.001), suggesting that MSH3 abrogation may be a predictor of metastatic disease or even favor tumor cell spread in MLH1-deficient colorectal cancers.

Elevation Change of the Southern Greenland Ice Sheet from Satellite Radar Altimeter Data

NASA Technical Reports Server (NTRS)

Haines, Bruce J.

1999-01-01

Long-term changes in the thickness of the polar ice sheets are important indicators of climate change. Understanding the contributions to the global water mass balance from the accumulation or ablation of grounded ice in Greenland and Antarctica is considered crucial for determining the source of the about 2 mm/yr sea-level rise in the last century. Though the Antarctic ice sheet is much larger than its northern counterpart, the Greenland ice sheet is more likely to undergo dramatic changes in response to a warming trend. This can be attributed to the warmer Greenland climate, as well as a potential for amplification of a global warming trend in the polar regions of the Northern Hemisphere. In collaboration with Drs. Curt Davis and Craig Kluever of the University of Missouri, we are using data from satellite radar altimeters to measure changes in the elevation of the Southern Greenland ice sheet from 1978 to the present. Difficulties with systematic altimeter measurement errors, particularly in intersatellite comparisons, beset earlier studies of the Greenland ice sheet thickness. We use altimeter data collected contemporaneously over the global ocean to establish a reference for correcting ice-sheet data. In addition, the waveform data from the ice-sheet radar returns are reprocessed to better determine the range from the satellite to the ice surface. At JPL, we are focusing our efforts principally on the reduction of orbit errors and range biases in the measurement systems on the various altimeter missions. Our approach emphasizes global characterization and reduction of the long-period orbit errors and range biases using altimeter data from NASA's Ocean Pathfinder program. Along-track sea-height residuals are sequentially filtered and backwards smoothed, and the radial orbit errors are modeled as sinusoids with a wavelength equal to one revolution of the satellite. The amplitudes of the sinusoids are treated as exponentially-correlated noise processes with a time-constant of six days. Measurement errors (e.g., altimeter range bias) are simultaneously recovered as constant parameters. The corrections derived from the global ocean analysis are then applied over the Greenland ice sheet. The orbit error and measurement bias corrections for different missions are developed in a single framework to enable robust linkage of ice-sheet measurements from 1978 to the present. In 1998, we completed our re-evaluation of the 1978 Seasat and 1985-1989 Geosat Exact Repeat Mission data. The estimates of ice thickness over Southern Greenland (south of 72N and above 2000 m) from 1978 to 1988 show large regional variations (+/-18 cm/yr), but yield an overall rate of +1.5 +/- 0.5 cm/yr (one standard error). Accounting for systematic errors, the estimate may not be significantly different from the null growth rate. The average elevation change from 1978 to 1988 is too small to assess whether the Greenland ice sheet is undergoing a long-term change.

Streamlining the Design Tradespace for Earth Imaging Constellations

NASA Technical Reports Server (NTRS)

Nag, Sreeja; Hughes, Steven P.; Le Moigne, Jacqueline J.

2016-01-01

Satellite constellations and Distributed Spacecraft Mission (DSM) architectures offer unique benefits to Earth observation scientists and unique challenges to cost estimators. The Cost and Risk (CR) module of the Tradespace Analysis Tool for Constellations (TAT-C) being developed by NASA Goddard seeks to address some of these challenges by providing a new approach to cost modeling, which aggregates existing Cost Estimating Relationships (CER) from respected sources, cost estimating best practices, and data from existing and proposed satellite designs. Cost estimation through this tool is approached from two perspectives: parametric cost estimating relationships and analogous cost estimation techniques. The dual approach utilized within the TAT-C CR module is intended to address prevailing concerns regarding early design stage cost estimates, and offer increased transparency and fidelity by offering two preliminary perspectives on mission cost. This work outlines the existing cost model, details assumptions built into the model, and explains what measures have been taken to address the particular challenges of constellation cost estimating. The risk estimation portion of the TAT-C CR module is still in development and will be presented in future work. The cost estimate produced by the CR module is not intended to be an exact mission valuation, but rather a comparative tool to assist in the exploration of the constellation design tradespace. Previous work has noted that estimating the cost of satellite constellations is difficult given that no comprehensive model for constellation cost estimation has yet been developed, and as such, quantitative assessment of multiple spacecraft missions has many remaining areas of uncertainty. By incorporating well-established CERs with preliminary approaches to approaching these uncertainties, the CR module offers more complete approach to constellation costing than has previously been available to mission architects or Earth scientists seeking to leverage the capabilities of multiple spacecraft working in support of a common goal.

Recent photometric monitoring of KIC 8462852, the detection of a potential repeat of the Kepler day 1540 dip and a plausible model

NASA Astrophysics Data System (ADS)

Bourne, R.; Gary, B. L.; Plakhov, A.

2018-04-01

This paper presents V- and g΄-band observations of the F2V star KIC 8462852, which exhibited enigmatic fade patterns in Kepler mission data. We introduce a transit simulation model for interpretation of these fades, and use it to interpret a 2017 August dip as a repeat of the Kepler day 1540 dip (D1540). We suggest the 2017 August and D1540 dips may be caused by a brown dwarf and an associated ring system in a 1601-d elliptical orbit. Transiting icy moons of the proposed brown dwarf, sublimating near periapsis like comets, could provide an explanation for the significant dips observed by Kepler, as well as the recent 2017 May to October dips and the long-term variation in flux detected by Simon et al. Whereas the presence of such a ring structure is attractive for its ability to explain short-term fade events, we do not address how such a ring system can be created and maintained. This speculation predicted a brightening of ˜1 per cent that occurred during October 2017. In addition, this scenario predicts that a set of dimming events, similar to those in 2013 (Kepler) and in 2017 (reported here), can be expected to repeat during 2021 October to 2022 January and a repeat of D1540 should occur on 2021 December 27.

Searching for Exoplanets using Artificial Intelligence

NASA Astrophysics Data System (ADS)

Pearson, Kyle Alexander; Palafox, Leon; Griffith, Caitlin Ann

2017-10-01

In the last decade, over a million stars were monitored to detect transiting planets. The large volume of data obtained from current and future missions (e.g. Kepler, K2, TESS and LSST) requires automated methods to detect the signature of a planet. Manual interpretation of potential exoplanet candidates is labor intensive and subject to human error, the results of which are difficult to quantify. Here we present a new method of detecting exoplanet candidates in large planetary search projects which, unlike current methods uses a neural network. Neural networks, also called ``deep learning'' or ``deep nets'', are a state of the art machine learning technique designed to give a computer perception into a specific problem by training it to recognize patterns. Unlike past transit detection algorithms, the deep net learns to characterize the data instead of relying on hand-coded metrics that humans perceive as the most representative. Exoplanet transits have different shapes, as a result of, e.g. the planet's and stellar atmosphere and transit geometry. Thus, a simple template does not suffice to capture the subtle details, especially if the signal is below the noise or strong systematics are present. Current false-positive rates from the Kepler data are estimated around 12.3% for Earth-like planets and there has been no study of the false negative rates. It is therefore important to ask how the properties of current algorithms exactly affect the results of the Kepler mission and, future missions such as TESS, which flies next year. These uncertainties affect the fundamental research derived from missions, such as the discovery of habitable planets, estimates of their occurrence rates and our understanding about the nature and evolution of planetary systems.

Electrophoresis tests on STS-3 and ground control experiments - A basis for future biological sample selections

NASA Technical Reports Server (NTRS)

Morrison, D. R.; Lewis, M. L.

1982-01-01

Static zone electrophoresis is an electrokinetic method of separating macromolecules and small particles. However, its application for the isolation of biological cells and concentrated protein solutions is limited by sedimentation and convection. Microgravity eliminates or reduces sedimentation, floatation, and density-driven convection arising from either Joule heating or concentration differences. The advantages of such an environment were first demonstrated in space during the Apollo 14 and 16 missions. In 1975 the Electrophoresis Technology Experiment (MA-011) was conducted during the Apollo-Soyuz Test Project flight. In 1979 a project was initiated to repeat the separations of human kidney cells. One of the major objectives of the Electrophoresis Equipment Verification Tests (EEVT) on STS-3 was to repeat and thereby validate the first successful electrophoretic separation of human kidney cells. Attention is given to the EEVT apparatus, the preflight electrophoresis, and inflight operational results.

IONAC-Lite

NASA Technical Reports Server (NTRS)

Torgerson, Jordan L.; Clare, Loren P.; Pang, Jackson

2011-01-01

The Interplanetary Overlay Net - working Protocol Accelerator (IONAC) described previously in The Inter - planetary Overlay Networking Protocol Accelerator (NPO-45584), NASA Tech Briefs, Vol. 32, No. 10, (October 2008) p. 106 (http://www.techbriefs.com/component/ content/article/3317) provides functions that implement the Delay Tolerant Networking (DTN) bundle protocol. New missions that require high-speed downlink-only use of DTN can now be accommodated by the unidirectional IONAC-Lite to support high data rate downlink mission applications. Due to constrained energy resources, a conventional software implementation of the DTN protocol can provide only limited throughput for any given reasonable energy consumption rate. The IONAC-Lite DTN Protocol Accelerator is able to reduce this energy consumption by an order of magnitude and increase the throughput capability by two orders of magnitude. In addition, a conventional DTN implementation requires a bundle database with a considerable storage requirement. In very high downlink datarate missions such as near-Earth radar science missions, the storage space utilization needs to be maximized for science data and minimized for communications protocol-related storage needs. The IONAC-Lite DTN Protocol Accelerator is implemented in a reconfigurable hardware device to accomplish exactly what s needed for high-throughput DTN downlink-only scenarios. The following are salient features of the IONAC-Lite implementation: An implementation of the Bundle Protocol for an environment that requires a very high rate bundle egress data rate. The C&DH (command and data handling) subsystem is also expected to be very constrained so the interaction with the C&DH processor and the temporary storage are minimized. Fully pipelined design so that bundle processing database is not required. Implements a lookup table-based approach to eliminate multi-pass processing requirement imposed by the Bundle Protocol header s length field structure and the SDNV (self-delimiting numeric value) data field formatting. 8-bit parallel datapath to support high data-rate missions. Reduced resource utilization implementation for missions that do not require custody transfer features. There was no known implementation of the DTN protocol in a field programmable gate array (FPGA) device prior to the current implementation. The combination of energy and performance optimization that embodies this design makes the work novel.

Muscle fatigue caused by repeated aerial combat maneuvering exercises.

PubMed

Oksa, J; Hämäläinen, O; Rissanen, S; Salminen, M; Kuronen, P

1999-06-01

Little is known about the development of in-flight muscular fatigue during repeated flights. This study was conducted to evaluate muscular fatigue in different upper body and neck muscles during repeated aerial combat maneuvering exercises. Six pilots volunteered as test subjects. They performed one-to-one dog fight exercise three times (1 pilot, four times) in one day. During the flights, the pilots' electromyographic activity (EMG) was measured from the abdomen, back, neck and lateral neck. The mean muscular strain for each muscle was calculated. Before the first flight and after each flight, the maximal isometric strength of each muscle was measured. The results showed that maximal isometric strength between the first and last measurement decreased in the back, neck (p < 0.05) and lateral neck muscles. While the G-stress remained the same, the muscular strain during exercises increased in every muscle, but was significant only in neck and lateral neck (p < 0.05-0.01). Due to these changes, the fatigue index in the neck and lateral neck muscles was 2.0-2.1, and 1.3-1.4 (1.0 = no fatigue) in the abdomen and back muscles. Repeated aerial combat maneuvering exercises caused fatigue in every muscle studied. The fatigue was greater in the neck area, which may increase the risk for neck injuries, and may reduce mission effectiveness. The fighter pilots' muscular strength and endurance in the neck area are subjected to very high demands, especially if exercises are repeated several times. The recovery of the neck muscles from fatigue after repetitive exercises should receive special attention.

Unresolved Galaxy Classifier for ESA/Gaia mission: Support Vector Machines approach

NASA Astrophysics Data System (ADS)

Bellas-Velidis, Ioannis; Kontizas, Mary; Dapergolas, Anastasios; Livanou, Evdokia; Kontizas, Evangelos; Karampelas, Antonios

A software package Unresolved Galaxy Classifier (UGC) is being developed for the ground-based pipeline of ESA's Gaia mission. It aims to provide an automated taxonomic classification and specific parameters estimation analyzing Gaia BP/RP instrument low-dispersion spectra of unresolved galaxies. The UGC algorithm is based on a supervised learning technique, the Support Vector Machines (SVM). The software is implemented in Java as two separate modules. An offline learning module provides functions for SVM-models training. Once trained, the set of models can be repeatedly applied to unknown galaxy spectra by the pipeline's application module. A library of galaxy models synthetic spectra, simulated for the BP/RP instrument, is used to train and test the modules. Science tests show a very good classification performance of UGC and relatively good regression performance, except for some of the parameters. Possible approaches to improve the performance are discussed.

A torsion balance for impulse and thrust measurements of micro-Newton thrusters

NASA Astrophysics Data System (ADS)

Yang, Yuan-Xia; Tu, Liang-Cheng; Yang, Shan-Qing; Luo, Jun

2012-01-01

This paper reports the performance of a torsion-type thrust stand suitable for studies of micro-Newton thrusters, which is developed for ground testing the micro-Newton thruster in Chinese Test of the Equivalence Principle with Optical readout space mission. By virtue of specially suspending design and precise assembly of torsion balance configuration, the thrust stand with load capacity up to several kilograms is able to measure the impulse bit up to 1350 μNs with a resolution of 0.47 μNs, and the average thrust up to 264 μN with a resolution of 0.09 μN in both open and close loop operation. A pulsed plasma thruster, the preliminary prototype developed for Chinese TEPO space mission, is tested by the thrust stand, and the results reveal that the average impulse bit per pulse is measured to be 58.4 μNs with a repeatability of about 5%.

HY-2A altimetry satellite GPS orbits processing and performances

NASA Astrophysics Data System (ADS)

Mercier, F.; Houry, S.; Couhert, A.; Cerri, L.

2012-04-01

The Chinese HY-2A altimetry satellite is on the mission orbit since 1st october 2011. This satellite uses a Doris receiver (French cooperation), a GPS receiver and a SLR retro-reflector for the precise orbit determination. The GPS is a dual frequency semi-codeless receiver. Precise orbits are computed at CNES on the basis of 7 days arcs since the beginning of the mission (repeat cycle is 14 days). This presentation describes the current processing performed at CNES for this satellite. The GPS only orbits perform very well and are compared with the Doris only orbits (floating ambiguity resolution, as for Jason 1 and 2). SLR measurements are also available at ILRS, and allow an external validation of the actual radial orbit performance. This talk adresses the current status of POE solutions and the prospects for improvement based on the preliminary analysis of the tracking data.

Gaia: unravelling the chemical and dynamical history of our Galaxy

NASA Astrophysics Data System (ADS)

Pancino, E.

The Gaia astrometric mission - the Hipparcos successor - is described in some detail, with its three instruments: the two (spectro)photometers (BP and RP) covering the range 330-1050 nm, the white light (G-band) imager dedicated to astrometry, and the radial velocity spectrometer (RVS) covering the range 847-874 nm at a resolution R≃11500. The whole sky will be scanned repeatedly providing data for ˜109 point-like objects, down to a magnitude of V≃20, aiming to the full 6D reconstruction of the Milky Way kinematical and dinamical structure with unprecendented precision. The horizon of scientific questions that can find an answer with such a set of data is vast, including besides the Galaxy: Solar system studies, stellar astrophysics, exoplanets, supernovae, Local group physics, unresolved galaxies, Quasars, and fundamental physics. The Italian involvement in the mission preparation is briefly outlined.

Biological instrumentation for the Viking 1975 mission to Mars.

PubMed

Klein, H P; Vishniac, W

1972-01-01

A brief introduction is given on why Mars is of interest from a biological point of view, along with an overview of the Viking 1975 mission. Details are given about the four biology instruments aboard the spacecraft and the experiments for which they are to be used. These are: the carbon assimilation experiment to determine whether the soil is biologically active, by incubation in presence of 14C-labelled CO and CO2 (known to be present in the Martian atmosphere); the label release experiment to detect metabolic activity by the release of radioactive CO2, from 14C-labelled simple organic substrates; the gas exchange experiment to detect biological activity by repeated gas chromatography analysis of soil samples; the light scattering experiment, where increase of scattering and decrease of light transmission would indicate the growth of organisms. Examples are given of data obtained with terrestrial soils in these experiments.

Cognitive demand of human sensorimotor performance during an extended space mission: a dual-task study.

PubMed

Bock, Otmar; Weigelt, Cornelia; Bloomberg, Jacob J

2010-09-01

Two previous single-case studies found that the dual-task costs of manual tracking plus memory search increased during a space mission, and concluded that sensorimotor deficits during spaceflight may be related to cognitive overload. Since dual-task costs were insensitive to the difficulty of memory search, the authors argued that the overload may reflect stress-related problems of multitasking, rather than a scarcity of specific cognitive resources. Here we expand the available database and compare different types of concurrent task. Three subjects were repeatedly tested before, during, and after an extended mission on the International Space Station (ISS). They performed an unstable tracking task and four reaction-time tasks, both separately and concurrently. Inflight data could only be obtained during later parts of the mission. The tracking error increased from pre- to in flight by a factor of about 2, both under single- and dual-task conditions. The dual-task costs with a reaction-time task requiring rhythm production was 2.4 times higher than with a reaction-time task requiring visuo-spatial transformations, and 8 times higher than with a regular choice reaction-time task. Long-term sensorimotor deficits during spaceflight may reflect not only stress, but also a scarcity of resources related to complex motor programming; possibly those resources are tied up by sensorimotor adaptation to the space environment.

Cassini Titan Flybys: The Next Year (April 2012 through April 2013)

NASA Astrophysics Data System (ADS)

Ray, T.; Burton, M.; Pitesky, J. E.; Steadman, K.; Roy, M.

2012-04-01

This poster describes the scientific, engineering, and operations planning for a Discovery / New Frontiers class Titan airplane mission, AVIATR (Aerial Vehicle for In-situ and Airborne Titan Reconnaissance). The mission would focus on Titan's surface and atmospheric diversity, using high-resolution imaging, near-infrared spectroscopy, a haze spectrometer, and atmospheric structure measurements. Previous mission studies have elected to use hot-air balloons to achieve similar science goals. These hot-air balloon concepts require the waste heat from inefficient thermocouple-based Radioisotope Thermoelectric Generators (RTGs) for buoyancy. New Advanced Stirling Radioisotope Generators (ASRGs) are much more efficient than RTGs both in terms of power produced per gram of plutonium-238 and the total watts-per-kilogram of the power unit itself. However, they are so efficient that they are much less effective for use in heating a hot-air balloon. Similarly, old-style RTGs produce insufficient specific power for heavier-than-air flight, but the use of 2 ASRGs can support a 120 kg airplane for a long-duration mission at Titan. The AVIATR airplane concept has several advantages in its science capabilities relative to a balloon, including the ability to target any site of interest, remaining on the dayside, stereo and repeat coverage, and easy altitude changes. It also possesses engineering advantages over a balloon like low total mass, a more straightforward deployment sequence, direct-to-Earth communications capability, and a more robust airframe.

Autonomous Science Decision Making for Mars Sample Return

NASA Technical Reports Server (NTRS)

Roush, Ted L.; Gulick, V.; Morris, R.; Gazis, P.; Benedix, G.; Glymour, C.; Ramsey, J.; Pedersen, L.; Ruzon, M.; Buntine, W.;

Botulinum toxin A injections and occupational therapy in children with unilateral spastic cerebral palsy: a randomized controlled trial.

PubMed

Lidman, Git; Nachemson, Ann; Peny-Dahlstrand, Marie; Himmelmann, Kate

2015-08-01

To investigate the effects of repeated botulinum toxin A (BoNT-A) injections combined with occupational therapy, including a splint, compared with occupational therapy alone on hand function in children with unilateral spastic cerebral palsy (USCP), in all International Classification of Functioning, Disability and Health (ICF) domains. This was a randomized controlled study, population-based and evaluator-blinded for primary outcome (October 2004 to September 2010). Twenty children (14 males; median age 3y 1mo) with USCP, recruited at a rehabilitation centre in Sweden, were assigned to one of two parallel groups using concealed allocation. In the course of one year, 10 children received occupational therapy, while 10 received repeated BoNT-A plus occupational therapy (BoNT-A/OT). Primary outcome (Assisting Hand Assessment [AHA]), and secondary outcome measures (range of movement [ROM], and Canadian Occupational Performance Measure), were measured at baseline, 3, 6, 9, and 12 months. AHA revealed a superior effect in the BoNT-A/OT group at 12 months: 6 out of 10 improved compared with 1 out of 10 in the occupational therapy group (p<0.03). A 95% Peskun exact confidence interval for the difference in proportions is given as 0.01 to 0.81. Secondary outcomes improved in both groups. Repeated BoNT-A/OT appeared superior to occupational therapy alone for bimanual performance in young children with USCP. Active ROM and goal performance improved in both groups. © 2015 Mac Keith Press.

Corner-corrected diagonal-norm summation-by-parts operators for the first derivative with increased order of accuracy

NASA Astrophysics Data System (ADS)

Del Rey Fernández, David C.; Boom, Pieter D.; Zingg, David W.

2017-02-01

Combined with simultaneous approximation terms, summation-by-parts (SBP) operators offer a versatile and efficient methodology that leads to consistent, conservative, and provably stable discretizations. However, diagonal-norm operators with a repeating interior-point operator that have thus far been constructed suffer from a loss of accuracy. While on the interior, these operators are of degree 2p, at a number of nodes near the boundaries, they are of degree p, and therefore of global degree p - meaning the highest degree monomial for which the operators are exact at all nodes. This implies that for hyperbolic problems and operators of degree greater than unity they lead to solutions with a global order of accuracy lower than the degree of the interior-point operator. In this paper, we develop a procedure to construct diagonal-norm first-derivative SBP operators that are of degree 2p at all nodes and therefore can lead to solutions of hyperbolic problems of order 2 p + 1. This is accomplished by adding nonzero entries in the upper-right and lower-left corners of SBP operator matrices with a repeating interior-point operator. This modification necessitates treating these new operators as elements, where mesh refinement is accomplished by increasing the number of elements in the mesh rather than increasing the number of nodes. The significant improvements in accuracy of this new family, for the same repeating interior-point operator, are demonstrated in the context of the linear convection equation.

A three-dimensional evaluation of a laser scanner and a touch-probe scanner.

PubMed

Persson, Anna; Andersson, Matts; Oden, Agneta; Sandborgh-Englund, Gunilla

2006-03-01

The fit of a dental restoration depends on quality throughout the entire manufacturing process. There is difficulty in assessing the surface topography of an object with a complex form, such as teeth, since there is no exact reference form. The purpose of this study was to determine the repeatability and relative accuracy of 2 dental surface digitization devices. A computer-aided design (CAD) technique was used for evaluation to calculate and present the deviations 3-dimensionally. Ten dies of teeth prepared for complete crowns were fabricated in presintered yttria-stabilized tetragonal zirconia (Y-TZP). The surfaces were digitized 3 times each with an optical or mechanical digitizer. The number of points in the point clouds from each reading were calculated and used as the CAD reference model (CRM). Alignments were performed by registration software that works by minimizing a distance criterion. In color-difference maps, the distribution of the discrepancies between the surfaces in the CRM and the 3-dimensional surface models was identified and located. The repeatability of both scanners was within 10 microm, based on SD and absolute mean values. The qualitative evaluation resulted in an even distribution of the deviations in the optical digitizer, whereas the dominating part of the surfaces in the mechanical digitizer showed no deviations. The relative accuracy of the 2 surface digitization devices was within +/- 6 microm, based on median values. The repeatability of the optical digitizer was comparable with the mechanical digitization device, and the relative accuracy was similar.

Comparison effect of azithromycin gel 2% with clindamycin gel 1% in patients with acne.

PubMed

Mokhtari, Fatemeh; Faghihi, Gita; Basiri, Akram; Farhadi, Sadaf; Nilforoushzadeh, Mohammadali; Behfar, Shadi

2016-01-01

Acne vulgaris is the most common skin disease. Local and systemic antimicrobial drugs are used for its treatment. But increasing resistance of Propionibacterium acnes to antibiotics has been reported. In a double-blind clinical trial, 40 patients with mild to moderate acne vulgaris were recruited. one side of the face was treated with Clindamycin Gel 1% and the other side with Azithromycin Topical Gel 2% BID for 8 weeks and then they were assessed. Average age was 21. 8 ± 7 years. 82.5% of them were female. Average number of papules, pustules and comedones was similarly reduced in both groups and, no significant difference was observed between the two groups (P > 0.05, repeated measurs ANOVA). The mean indexes of ASI and TLC also significantly decreased during treatment in both groups, no significant difference was observed between the two groups. (P > 0.05, repeated measurs ANOVA). Also, impact of both drugs on papules and pustules was 2-3 times greater than the effect on comedones. Average satisfaction score was not significant between the two groups (P = 0.6, repeated measurs ANOVA). finally, frequency distribution of complications was not significant between the two groups (P > 0.05, Fisher Exact test). Azithromycin gel has medical impact at least similar to Clindamycin Gel in treatment of mild to moderate acne vulgaris, and it may be consider as suitable drug for resistant acne to conventional topical therapy.

Out of This World Science, Down to Earth Prices

NASA Technical Reports Server (NTRS)

Kremic, Tibor; Hurford, Terry Anthony; Mandell, Avi; Arnold, Steven

2015-01-01

The National Aeronautics and Space Administration (NASA), along with the rest of government and the nation have become increasing cost conscious in recent years. This has resulted in renewed efforts at finding ways to do more with less. Planetary science is no exception. The 2013 Decadal Survey for Planetary Science made great efforts to understand the costs of proposed missions. The community has been asked to develop more affordable versions of mission concepts, especially in the flagship category. Many in the community continue to encourage NASA to prioritize lower cost missions at a more frequent cadence over fewer but larger missions. This presentation discusses a new tool in the planetary science arsenal to achieve a broad set of planetary science questions at costs that are lower, and in some cases dramatically lower, than other options in the past. Technology advances in pointing systems and the growing capabilities of stratospheric balloons, such as the ultra-long duration flights, have caught the attention of many in the planetary science community. A workshop was held in January 2012 to help planetary scientists and NASA better understand the capabilities of balloon borne platforms, along with their strengths and limitations. Perhaps most importantly, the workshop focused on the potential science that could be achieved. The science and engineering participants discussed what, if any, science can be achieved and why or how balloon platforms would offer an advantage. Since that first workshop, not only have further discussions and studies occurred within the community, but demonstration missions have been flown with compelling results. These balloon missions have shown that the science envisioned can indeed be achievable, that balloon platforms do offer some unique advantages; and that repeated flights can be implemented at relatively low cost. The presentation briefly summarizes the potential science and the characteristics of a balloon based observatory that make it desirable for some science investigations. The recent missions are described along with some of their challenges and achievements. Finally, a brief summary of options moving forward are considered.

Adaptation of a Fast Optimal Interpolation Algorithm to the Mapping of Oceangraphic Data

NASA Technical Reports Server (NTRS)

Menemenlis, Dimitris; Fieguth, Paul; Wunsch, Carl; Willsky, Alan

1997-01-01

A fast, recently developed, multiscale optimal interpolation algorithm has been adapted to the mapping of hydrographic and other oceanographic data. This algorithm produces solution and error estimates which are consistent with those obtained from exact least squares methods, but at a small fraction of the computational cost. Problems whose solution would be completely impractical using exact least squares, that is, problems with tens or hundreds of thousands of measurements and estimation grid points, can easily be solved on a small workstation using the multiscale algorithm. In contrast to methods previously proposed for solving large least squares problems, our approach provides estimation error statistics while permitting long-range correlations, using all measurements, and permitting arbitrary measurement locations. The multiscale algorithm itself, published elsewhere, is not the focus of this paper. However, the algorithm requires statistical models having a very particular multiscale structure; it is the development of a class of multiscale statistical models, appropriate for oceanographic mapping problems, with which we concern ourselves in this paper. The approach is illustrated by mapping temperature in the northeastern Pacific. The number of hydrographic stations is kept deliberately small to show that multiscale and exact least squares results are comparable. A portion of the data were not used in the analysis; these data serve to test the multiscale estimates. A major advantage of the present approach is the ability to repeat the estimation procedure a large number of times for sensitivity studies, parameter estimation, and model testing. We have made available by anonymous Ftp a set of MATLAB-callable routines which implement the multiscale algorithm and the statistical models developed in this paper.

Remote Sensing of Arctic and Boreal Atmospheric Composition from a Highly Elliptical Orbit

NASA Astrophysics Data System (ADS)

Nassar, Ray; McElroy, C. Tom; Walker, Kaley A.; McLinden, Chris; Sioris, Chris E.; Jones, Dylan B. A.; Martin, Randall V.; Rochon, Yves; Garand, Louis; Trischencko, Alexander P.

2016-04-01

The Polar Communications and Weather (PCW) mission is a proposed Canadian mission that aims to provide continuous meteorological observations and communications capacity over the Arctic and northern latitudes from a pair of satellites in a highly elliptical orbit (HEO) configuration. The Weather, Climate and Air quality (WCA) concept is a mission enhancement that completed a Phase A study through the Polar Highly Elliptical Orbit Science (PHEOS) program. The PHEOS-WCA instrument suite would consist of a high resolution Fourier Transform Spectrometer (FTS) operating in the mid-, near- and shortwave infrared and a UV-Visible grating Spectrometer (UVS), both with 2-dimensional imaging capability. These instruments would enable dense measurements of numerous quantities important for understanding weather (H2O and temperature profiles), climate (column-averaged CO2 and CH4) and air quality (tropospheric O3, CO, NO2, SO2, NH3, HCN, CH3OH, BrO, aerosols, ….) with a pixel size of 10×10 km2 or better and repeat time targeted at 2 hours or less. Our studies have demonstrated that HEO observations of CO2 offer major advantages over those from low earth orbit (LEO) for constraining CO2 surface sources and sinks in the Arctic and boreal regions, especially in the summer when there is the potential for the release of CO2 from permafrost thaw and boreal forest disturbances. This presentation will give an overview of the PHEOS-WCA mission concept, discuss its complementarity with upcoming international missions and provide an update on recent progress and challenges in moving forward.

Albedo and its relationship with seasonal surface roughness using repeat UAV survey across the Kangerlussuaq sector of the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Hubbard, A., II; Ryan, J.; Box, J. E.; Snooke, N.

2015-12-01

Surface albedo is a primary control on absorbed radiation and hence ice surface darkening is a powerful amplifier of melt across the margin of the Greenland ice sheet. To investigate the relationship between ice surface roughness and variations in albedo in space and time at ~dm resolution, a suite of Unmanned Aerial Vehicles (UAVs) were deployed from the margin of Russell Glacier between June and August, 2014. The UAVs were equipped with digital and multispectral cameras, GoPros, fast response broadband pyranometers and temperature and humidity sensors. The primary mission was regular repeat longitudinal transects attaining data from the margin to the equilibrium line 80 km into the ice sheet interior and which were complimented by selected watershed and catchment surveys. The pyranometers reliably measure bare ice surface albedo between 0.34 and 0.58 that correlate well against concurrent MODIS data (where available). Repeat digital photogrammetric analysis enables investigation of relationship between changing meso- and micro-scale albedo and melt processes modulated by ice surface roughness that, in turn, are related to the seasonally evolving surface energy balance recorded at three AWS on the flight path.

Life Cycle Management Considerations of Remotely Sensed Geospatial Data and Documentation for Long Term Preservation

NASA Technical Reports Server (NTRS)

Khayat, Mohammad G.; Kempler, Steven J.

2015-01-01

As geospatial missions age, one of the challenges for the usability of data is the availability of relevant and updated metadata with sufficient documentation that can be used by future generations of users to gain knowledge from the original data. Given that remote sensing data undergo many intermediate processing steps, for example, an understanding of the exact algorithms employed and the quality of that data produced, could be key considerations for these users. As interest in global climate data is increasing, documentation about older data, their origins, and provenance are valuable to first time users attempting to perform historical climate research or comparative analysis of global change. Incomplete or missing documentation could be what stands in the way of a new researcher attempting to use the data. Therefore, preservation of documentation and related metadata is sometimes just as critical as the preservation of the original observational data. The Goddard Earth Sciences - Data and Information Service Center (GES DISC), a NASA Earth science Distributed Active Archive Center (DAAC), that falls under the management structure of the Earth Science Data and Information System (ESDIS), is actively pursuing the preservation of all necessary artifacts needed by future users. In this paper we will detail the data custodial planning and the data lifecycle process developed for content preservation, our implementation of a Preservation System to safeguard documents and associated artifacts from legacy (older) missions, as well as detail lessons learned regarding access rights and confidentiality of information issues. We also elaborate on key points that made our preservation effort successful; the primary points being: the drafting of a governing baseline for historical data preservation from satellite missions, and using the historical baseline as a guide to content filtering of what documents to preserve. The Preservation System currently archives documentation content for High Resolution Dynamics Limb Sounder (HIRDLS), Upper Atmosphere Research Satellite (UARS), Total Ozone Mapping Spectrometer (TOMS), and the 1960's era Nimbus mission. Documentation from other missions like the Tropical Rainfall Measuring Mission (TRMM), the Ozone Monitoring Instrument (OMI), and the Atmospheric Infra-Red Sounder (AIRS) are also slated to be added to this repository, as well as the other mission datasets to be preserved at the GES DISC.

Summary of Altitude Pulse Testing of a 100-lbf L02/LCH4 Reaction Control Engine

NASA Technical Reports Server (NTRS)

Marshall, William M.; Kleinhenz, Julie E.

2011-01-01

Recently, liquid oxygen-liquid methane (LO2/LCH4) has been considered as a potential "green" propellant alternative for future exploration missions. The Propulsion and Cryogenic Advanced Development (PCAD) project has been tasked by NASA to develop this propulsion combination to enable safe and cost effective exploration missions. To date, limited experience with such combinations exist, and as a result a comprehensive test program is critical to demonstrating the viability of implementing such a system. The NASA Glenn Research Center has conducted a test program of a 100-lbf (445-N) reaction control engine (RCE) at the center s Altitude Combustion Stand (ACS), focusing on altitude testing over a wide variety of operational conditions. The ACS facility includes a unique propellant conditioning feed system (PCFS) which allows precise control of propellant inlet conditions to the engine. Engine performance as a result of these inlet conditions was examined extensively during the test program. This paper is a companion to the previous specific impulse testing paper, and discusses the pulsed mode operation portion of testing, with a focus on minimum impulse bit (I-bit) and repeatable pulse performance. The engine successfully demonstrated target minimum impulse bit performance at all conditions, as well as successful demonstration of repeatable pulse widths. Some anomalous conditions experienced during testing are also discussed, including a double pulse phenomenon which was not noted in previous test programs for this engine.

Detachment dynamics of colloidal spheres with adhesive interactions

NASA Astrophysics Data System (ADS)

Bergenholtz, J.

2018-04-01

Escape of colloidal-size particles from various kinds of solids, such as aggregates and surfaces, occurs in a wide variety of settings of both fundamental and applied scientific interest. In this paper an exact solution for the detachment of adhesive spheres from each other by means of diffusion is presented. The solution takes into account repeated detachment and reattachment events in the course of time on the way toward the permanently separated state. For strongly adhesive spheres this state is approached in an exponential manner essentially regardless of how the bound state is specified. The analytical solution is shown to capture semiquantitatively the escape from more realistic potential wells using a mapping procedure whereby equality of second virial coefficients is imposed.

Structural DNA Nanotechnology: From Design to Applications

PubMed Central

Zadegan, Reza M.; Norton, Michael L.

2012-01-01

The exploitation of DNA for the production of nanoscale architectures presents a young yet paradigm breaking approach, which addresses many of the barriers to the self-assembly of small molecules into highly-ordered nanostructures via construct addressability. There are two major methods to construct DNA nanostructures, and in the current review we will discuss the principles and some examples of applications of both the tile-based and DNA origami methods. The tile-based approach is an older method that provides a good tool to construct small and simple structures, usually with multiply repeated domains. In contrast, the origami method, at this time, would appear to be more appropriate for the construction of bigger, more sophisticated and exactly defined structures. PMID:22837684

Pattern-set generation algorithm for the one-dimensional multiple stock sizes cutting stock problem

NASA Astrophysics Data System (ADS)

Cui, Yaodong; Cui, Yi-Ping; Zhao, Zhigang

2015-09-01

A pattern-set generation algorithm (PSG) for the one-dimensional multiple stock sizes cutting stock problem (1DMSSCSP) is presented. The solution process contains two stages. In the first stage, the PSG solves the residual problems repeatedly to generate the patterns in the pattern set, where each residual problem is solved by the column-generation approach, and each pattern is generated by solving a single large object placement problem. In the second stage, the integer linear programming model of the 1DMSSCSP is solved using a commercial solver, where only the patterns in the pattern set are considered. The computational results of benchmark instances indicate that the PSG outperforms existing heuristic algorithms and rivals the exact algorithm in solution quality.

Preparation of Small RNAs Using Rolling Circle Transcription and Site-Specific RNA Disconnection.

PubMed

Wang, Xingyu; Li, Can; Gao, Xiaomeng; Wang, Jing; Liang, Xingguo

2015-01-13

A facile and robust RNA preparation protocol was developed by combining rolling circle transcription (RCT) with RNA cleavage by RNase H. Circular DNA with a complementary sequence was used as the template for promoter-free transcription. With the aid of a 2'-O-methylated DNA, the RCT-generated tandem repeats of the desired RNA sequence were disconnected at the exact end-to-end position to harvest the desired RNA oligomers. Compared with the template DNA, more than 4 × 10(3) times the amount of small RNA products were obtained when modest cleavage was carried out during transcription. Large amounts of RNA oligomers could easily be obtained by simply increasing the reaction volume.

Combining living anionic polymerization with branching reactions in an iterative fashion to design branched polymers.

PubMed

Higashihara, Tomoya; Sugiyama, Kenji; Yoo, Hee-Soo; Hayashi, Mayumi; Hirao, Akira

2010-06-16

This paper reviews the precise synthesis of many-armed and multi-compositional star-branched polymers, exact graft (co)polymers, and structurally well-defined dendrimer-like star-branched polymers, which are synthetically difficult, by a commonly-featured iterative methodology combining living anionic polymerization with branched reactions to design branched polymers. The methodology basically involves only two synthetic steps; (a) preparation of a polymeric building block corresponding to each branched polymer and (b) connection of the resulting building unit to another unit. The synthetic steps were repeated in a stepwise fashion several times to successively synthesize a series of well-defined target branched polymers. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Orthostatic Hypotension After Long-Duration Space Flight: NASA's Experiences from the International Space Station

NASA Technical Reports Server (NTRS)

Lee, Stuart M. C.; Feiveson, Alan H.; Stenger, Michael B.; Stein, Sydney P.; Platts, Steven H.

2011-01-01

Our laboratory previously reported that the incidence of orthostatic hypotension (OH) was greater after long- than short-duration spaceflight in astronauts who participated in Mir Space Station and Space Shuttle missions. To confirm and extend these findings, we retrospectively examined tilt test data from International Space Station (ISS) and Shuttle astronauts. We anticipated that the proportion of ISS astronauts experiencing OH would be high on landing day and the number of days to recover greater after long- than short-duration missions. Methods: Twenty ISS and 66 Shuttle astronauts participated in 10-min 80? head-up tilt tests 10 d before launch (L-10), on landing day (R+0) or 1 d after landing (R+1). Data from 5 ISS astronauts tested on R+0 or R+1 who used non-standard countermeasures were excluded. Many astronauts repeated the test 3 d (R+3) after landing. Fisher?s Exact Test was used to compare the ability of ISS and Shuttle astronauts to complete the tilt test on R+0. Cox regression was used to identify cardiovascular parameters that were associated with test completion across all tests, and mixed model analysis was used to compare the change and recovery rates between ISS and Shuttle astronauts. In these analyses, ISS data from R+0 and R+1 were pooled to provide sufficient statistical power. Results: The proportion of astronauts who completed the tilt test on R+0 without OH was less in ISS than in Shuttle astronauts (p=0.03). On R+0, only 2 of 6 ISS astronauts completed the test compared to 53 of 66 (80%) Shuttle astronauts. However, 8 of 9 ISS astronauts completed the test on R+1. On R+3, 13 of 15 (87%) of the ISS and 19 of 19 (100%) of the Shuttle astronauts completed the 10-min test. An index comprised of stroke volume and diastolic blood pressure provided a very good prediction of overall tilt survival. This index was altered by spaceflight similarly for both groups soon after landing (pooled R+0 and R+ 1), but ISS astronauts did not recover at the same rate as Shuttle astronauts (p=0.007). Conclusions: The proportion of ISS astronauts who could not complete the tilt test on R+0 due to OH (4 of 6) is similar to that reported in astronauts who flew on Mir (5 of 6). Further, cardiovascular parameters most closely associated with OH recover more slowly after long- compared to short-duration spaceflight.

The mean sea surface height and geoid along the Geosat subtrack from Bermuda to Cape Cod

NASA Astrophysics Data System (ADS)

Kelly, Kathryn A.; Joyce, Terrence M.; Schubert, David M.; Caruso, Michael J.

1991-07-01

Measurements of near-surface velocity and concurrent sea level along an ascending Geosat subtrack were used to estimate the mean sea surface height and the Earth's gravitational geoid. Velocity measurements were made on three traverses of a Geosat subtrack within 10 days, using an acoustic Doppler current profiler (ADCP). A small bias in the ADCP velocity was removed by considering a mass balance for two pairs of triangles for which expendable bathythermograph measurements were also made. Because of the large curvature of the Gulf Stream, the gradient wind balance was used to estimate the cross-track component of geostrophic velocity from the ADCP vectors; this component was then integrated to obtain the sea surface height profile. The mean sea surface height was estimated as the difference between the instantaneous sea surface height from ADCP and the Geosat residual sea level, with mesoscale errors reduced by low-pass filtering. The error estimates were divided into a bias, tilt, and mesoscale residual; the bias was ignored because profiles were only determined within a constant of integration. The calculated mean sea surface height estimate agreed with an independent estimate of the mean sea surface height from Geosat, obtained by modeling the Gulf Stream as a Gaussian jet, within the expected errors in the estimates: the tilt error was 0.10 m, and the mesoscale error was 0.044 m. To minimize mesoscale errors in the estimate, the alongtrack geoid estimate was computed as the difference between the mean sea level from the Geosat Exact Repeat Mission and an estimate of the mean sea surface height, rather than as the difference between instantaneous profiles of sea level and sea surface height. In the critical region near the Gulf Stream the estimated error reduction using this method was about 0.07 m. Differences between the geoid estimate and a gravimetric geoid were not within the expected errors: the rms mesoscale difference was 0.24 m rms.

Southern Alaska Glaciers: Spatial and Temporal Variations in Ice Volume

NASA Technical Reports Server (NTRS)

Sauber, J.; Molnia, B. F.; Lutchke, S.; Rowlands, D.; Harding, D.; Carabajal, C.; Hurtado, J. M.; Spade, G.

2004-01-01

Although temperate mountain glaciers comprise less than 1% of the glacier-covered area on Earth, they are important because they appear to be melting rapidly under present climatic conditions and, therefore, make significant contributions to rising sea level. In this study, we use ICESat observations made in the last 1.5 years of southern Alaska glaciers to estimate ice elevation profiles, ice surface slopes and roughness, and bi-annual and/or annual ice elevation changes. We report initial results from the near coastal region between Yakutat Bay and Cape Suckling that includes the Malaspina and Bering Glaciers. We show and interpret ice elevations changes across the lower reaches of the Bagley Ice Valley for the period between October 2003 and May 2004. In addition, we use off-nadir pointing observations to reference tracks over the Bering and Malaspina Glaciers in order to estimate annual ice elevation change. Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and Shuttle Radar Topography Mission (SRTM) derived DEMs are used to estimate across track regional slopes between ICESat data acquisitions. Although the distribution and quantity of ICESat elevation profiles with multiple, exact repeat data is currently limited in Alaska, individual ICESat data tracks, provide an accurate reference surface for comparison to other elevation data (e.g. ASTER and SRTM X- and C-band derived DEMs). Specifically we report the elevation change over the Malaspina Glacier's piedmont lobe between a DEM derived from SRTM C-band data acquired in Feb. 2000 and ICESat Laser #2b data from Feb.-March 2004. We also report use of ICESat elevation data to enhance ASTER derived absolute DEMs. Mountain glaciers generally have rougher surfaces and steeper regional slopes than the ice sheets for which the ICESat design was optimized. Therefore, rather than averaging ICESat observations over large regions or relying on crossovers, we are working with well-located ICESat footprint returns to estimate glacier ice elevations and surface characteristics. Additional information is included in the original extended abstract.

Reliability-based trajectory optimization using nonintrusive polynomial chaos for Mars entry mission

NASA Astrophysics Data System (ADS)

Huang, Yuechen; Li, Haiyang

2018-06-01

This paper presents the reliability-based sequential optimization (RBSO) method to settle the trajectory optimization problem with parametric uncertainties in entry dynamics for Mars entry mission. First, the deterministic entry trajectory optimization model is reviewed, and then the reliability-based optimization model is formulated. In addition, the modified sequential optimization method, in which the nonintrusive polynomial chaos expansion (PCE) method and the most probable point (MPP) searching method are employed, is proposed to solve the reliability-based optimization problem efficiently. The nonintrusive PCE method contributes to the transformation between the stochastic optimization (SO) and the deterministic optimization (DO) and to the approximation of trajectory solution efficiently. The MPP method, which is used for assessing the reliability of constraints satisfaction only up to the necessary level, is employed to further improve the computational efficiency. The cycle including SO, reliability assessment and constraints update is repeated in the RBSO until the reliability requirements of constraints satisfaction are satisfied. Finally, the RBSO is compared with the traditional DO and the traditional sequential optimization based on Monte Carlo (MC) simulation in a specific Mars entry mission to demonstrate the effectiveness and the efficiency of the proposed method.

Autonomous Aerobraking Using Thermal Response Surface Analysis

NASA Technical Reports Server (NTRS)

Prince, Jill L.; Dec, John A.; Tolson, Robert H.

2007-01-01

Aerobraking is a proven method of significantly increasing the science payload that can be placed into low Mars orbits when compared to an all propulsive capture. However, the aerobraking phase is long and has mission cost and risk implications. The main cost benefit is that aerobraking permits the use of a smaller and cheaper launch vehicle, but additional operational costs are incurred during the long aerobraking phase. Risk is increased due to the repeated thermal loading of spacecraft components and the multiple attitude and propulsive maneuvers required for successful aerobraking. Both the cost and risk burdens can be significantly reduced by automating the aerobraking operations phase. All of the previous Mars orbiter missions that have utilized aerobraking have increasingly relied on onboard calculations during aerobraking. Even though the temperature of spacecraft components has been the limiting factor, operational methods have relied on using a surrogate variable for mission control. This paper describes several methods, based directly on spacecraft component maximum temperature, for autonomously predicting the subsequent aerobraking orbits and prescribing apoapsis propulsive maneuvers to maintain the spacecraft within specified temperature limits. Specifically, this paper describes the use of thermal response surface analysis in predicting the temperature of the spacecraft components and the corresponding uncertainty in this temperature prediction.

Improving the recognition of near-miss events on NASA missions

NASA Astrophysics Data System (ADS)

Dillon, R. L.; Rogers, E. W.; Madsen, P.; Tinsley, C. H.

Organizations that ignore near-miss data may be inappropriately rewarding risky behavior. If managers engage in risky behavior and succeed, research shows that these managers are likely to be promoted without close scrutiny of their risky decisions, even if the success is because of good fortune. Over time such risk taking compounds as similar near-misses are repeatedly observed and the ability to recognize anomalies and document the events decreases (i.e., normalization of deviance). History from the shuttle program shows that only the occasional large failure increases attention to anomalies again. This research demonstrates the presence of normalization of deviance in NASA missions and also examines a factor (the significance of the project) that may increase people's awareness of near-misses to counter this trend. Increasing awareness of chance success should increase the likelihood that significant learning can occur from the mission regardless of outcome. We conclude with prescriptions for project managers based on several on-going activities at NASA Goddard Space Flight Center (GSFC) to improve organizational learning. We discuss how these efforts can contribute to reducing near-miss bias and the normalization of deviance. This research should help organizations design learning processes that draw lessons from near-misses.

Global Precipitation Measurement (GPM) Orbit Design and Autonomous Maneuvers

NASA Technical Reports Server (NTRS)

Folta, David; Mendelsohn, Chad

2003-01-01

The NASA Goddard Space Flight Center's Global Precipitation Measurement (GPM) mission will meet a challenge of measuring worldwide precipitation every three hours. The GPM spacecraft, part of a constellation, will be required to maintain a circular orbit in a high drag environment to accomplish this challenge. Analysis by the Flight Dynamics Analysis Branch has shown that the prime orbit altitude of 40% is necessary to prevent ground track repeating. Combined with goals to minimize maneuver impacts to science data collection and enabling reasonable long-term orbit predictions, the GPM project has decided to fly an autonomous maneuver system. This system is a derivative of the successful New Millennium Program technology flown onboard the Earth Observing-1 mission. This paper presents the driving science requirements and goals of the mission and shows how they will be met. Analysis of the orbit optimization and the AV requirements for several ballistic properties are presented. The architecture of the autonomous maneuvering system to meet the goals and requirements is presented along with simulations using a GPM prototype. Additionally, the use of the GPM autonomous system to mitigate possible collision avoidance and to aid other spacecraft systems during navigation outages is explored.

Internal waves in the Gulf of California - Observations from a spaceborne radar

NASA Technical Reports Server (NTRS)

Fu, L.-L.; Holt, B.

1984-01-01

Pronounced signatures of internal waves were detected repeatedly in the Gulf of California by the Seasat synthetic aperture radar (SAR). A series of nine images with exactly repeating ground coverage was used to study the temporal variability of the internal wave field in the area. It was found that the number of observed wave groups was highly correlated with the strength of the local tides: the maximum number occurred during spring tides and the minimum number occurred during neap tides, indicating that the internal waves were tidally forced. Most of the wave activity was found to the north of 28 deg N where the tides were the strongest in the Gulf. The application of a simple, nonlinear internal wave model to the observations indicated that the peak-to-peak amplitude of the observed waves was about 50 m with an uncertainty of a factor of 2. The estimated upper bound for the rate of the loss of tidal energy to internal waves was about 5 x 10 to the 15th erg/s, representing only 10 percent of the rate of the dissipation of the dominant M2 tide in the Gulf.

DNABIT Compress – Genome compression algorithm

PubMed Central

Rajarajeswari, Pothuraju; Apparao, Allam

2011-01-01

Data compression is concerned with how information is organized in data. Efficient storage means removal of redundancy from the data being stored in the DNA molecule. Data compression algorithms remove redundancy and are used to understand biologically important molecules. We present a compression algorithm, “DNABIT Compress” for DNA sequences based on a novel algorithm of assigning binary bits for smaller segments of DNA bases to compress both repetitive and non repetitive DNA sequence. Our proposed algorithm achieves the best compression ratio for DNA sequences for larger genome. Significantly better compression results show that “DNABIT Compress” algorithm is the best among the remaining compression algorithms. While achieving the best compression ratios for DNA sequences (Genomes),our new DNABIT Compress algorithm significantly improves the running time of all previous DNA compression programs. Assigning binary bits (Unique BIT CODE) for (Exact Repeats, Reverse Repeats) fragments of DNA sequence is also a unique concept introduced in this algorithm for the first time in DNA compression. This proposed new algorithm could achieve the best compression ratio as much as 1.58 bits/bases where the existing best methods could not achieve a ratio less than 1.72 bits/bases. PMID:21383923

Chutes and Fissures in Greenland

NASA Image and Video Library

2015-05-12

Scientists and crew with NASA’s Operation IceBridge, which makes annual aerial surveys of polar ice, are wrapping up their seventh campaign over the Arctic. In spring 2015, the team began using a different research aircraft—an adapted C-130 Hercules. They also added four new high-priority targets in the rapidly changing region of northeast Greenland. Many of the flights, however, were routine. And that’s exactly the point; making measurements over the same path each year provides continuity between NASA’s Ice, Cloud, and Land Elevation Satellite (ICESat) missions—the first of which ended in 2009 and the second of which is scheduled for launch in 2017. Repeat measurements show how a landscape changes over time. One area that has been surveyed repeatedly is northern Greenland’s Ryder Glacier. This photograph, taken during the IceBridge flight on May 6, 2015, shows a large moulin—dozens of meters across—atop this glacier. Moulins are holes in the ice sheet that drain melt water from the ice sheet’s surface to the bottom or out to the sea. Scientists are working to figure out what happens to melt water once it enters a moulin.

Group B streptococcal serine-rich repeat proteins promote interaction with fibrinogen and vaginal colonization.

PubMed

Wang, Nai-Yu; Patras, Kathryn A; Seo, Ho Seong; Cavaco, Courtney K; Rösler, Berenice; Neely, Melody N; Sullam, Paul M; Doran, Kelly S

2014-09-15

Group B streptococcus (GBS) can cause severe disease in susceptible hosts, including newborns, pregnant women, and the elderly. GBS serine-rich repeat (Srr) surface glycoproteins are important adhesins/invasins in multiple host tissues, including the vagina. However, exact molecular mechanisms contributing to their importance in colonization are unknown. We have recently determined that Srr proteins contain a fibrinogen-binding region (BR) and hypothesize that Srr-mediated fibrinogen binding may contribute to GBS cervicovaginal colonization. In this study, we observed that fibrinogen enhanced wild-type GBS attachment to cervical and vaginal epithelium, and that this was dependent on Srr1. Moreover, purified Srr1-BR peptide bound directly to host cells, and peptide administration in vivo reduced GBS recovery from the vaginal tract. Furthermore, a GBS mutant strain lacking only the Srr1 "latching" domain exhibited decreased adherence in vitro and decreased persistence in a mouse model of GBS vaginal colonization, suggesting the importance of Srr-fibrinogen interactions in the female reproductive tract. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

River-damming, late-Quaternary rockslides in the Ötz Valley region (Tyrol, Austria)

NASA Astrophysics Data System (ADS)

Dufresne, A.; Ostermann, M.; Preusser, F.

2018-06-01

The Ötz Valley and adjacent regions in Tyrol (Austria) have been repeatedly affected by large rockslope failures following deglaciation. Six rockslides, each over 107 m3 in volume, were emplaced into the Ötz and Inn valleys, five of which formed persistent rockslide dams. Even though catastrophic rockslope failures are short-lived events (commonly minutes) they can have long-lasting impacts on the landscape. For example, large fans have built in the Ötz Valley and knickpoints persist at the former dam sites even though the Ötz River has eroded through the deposits during the past thousands of years; exact age-constraints of rockslide dam failure, however, are still scarce. Empirical, geomorphic stability indices from the literature successfully identified the least and the most stable dams of this group, whereas the rest remain inconclusive with some indices variably placing the dams in the stable, unstable, and uncertain categories. This shows (a) that further index calibrations and (b) better age constraints on dam formation and failure are needed, and (c) that the exact processes of dam failure are not always trivial to pinpoint for ancient (partially) breached dams. This study is a contribution towards better constraining the nature and landscape impact of dam formation following large rockslope failures.

Theoretical study of the dependence of single impurity Anderson model on various parameters within distributional exact diagonalization method

NASA Astrophysics Data System (ADS)

Syaina, L. P.; Majidi, M. A.

2018-04-01

Single impurity Anderson model describes a system consisting of non-interacting conduction electrons coupled with a localized orbital having strongly interacting electrons at a particular site. This model has been proven successful to explain the phenomenon of metal-insulator transition through Anderson localization. Despite the well-understood behaviors of the model, little has been explored theoretically on how the model properties gradually evolve as functions of hybridization parameter, interaction energy, impurity concentration, and temperature. Here, we propose to do a theoretical study on those aspects of a single impurity Anderson model using the distributional exact diagonalization method. We solve the model Hamiltonian by randomly generating sampling distribution of some conducting electron energy levels with various number of occupying electrons. The resulting eigenvalues and eigenstates are then used to define the local single-particle Green function for each sampled electron energy distribution using Lehmann representation. Later, we extract the corresponding self-energy of each distribution, then average over all the distributions and construct the local Green function of the system to calculate the density of states. We repeat this procedure for various values of those controllable parameters, and discuss our results in connection with the criteria of the occurrence of metal-insulator transition in this system.

STS-84 Atlantis on Pad 39-A after RSS roll back

NASA Technical Reports Server (NTRS)

1997-01-01

News media representatives watch and record as the Space Shuttle Atlantis in full launch configuration is revealed after the Rotating Service Structure (RSS) is rotated back at Launch Pad 39A. Rollback of the RSS is a major preflight milestone, typically occurring during the T-11-hour hold on L-1 (the day before launch). Atlantis and its crew of seven are in final preparations for liftoff on Mission STS-84, the sixth of nine planned dockings of the Space Shuttle with the Russian Space Station Mir. Launch is scheduled at about 4:08 a.m. during an approximately 7-minute launch window. The exact liftoff time will be determined about 90 minutes prior to launch, based on the most current location of Mir.

MICROSCOPE Mission: First Results of a Space Test of the Equivalence Principle.

PubMed

Touboul, Pierre; Métris, Gilles; Rodrigues, Manuel; André, Yves; Baghi, Quentin; Bergé, Joël; Boulanger, Damien; Bremer, Stefanie; Carle, Patrice; Chhun, Ratana; Christophe, Bruno; Cipolla, Valerio; Damour, Thibault; Danto, Pascale; Dittus, Hansjoerg; Fayet, Pierre; Foulon, Bernard; Gageant, Claude; Guidotti, Pierre-Yves; Hagedorn, Daniel; Hardy, Emilie; Huynh, Phuong-Anh; Inchauspe, Henri; Kayser, Patrick; Lala, Stéphanie; Lämmerzahl, Claus; Lebat, Vincent; Leseur, Pierre; Liorzou, Françoise; List, Meike; Löffler, Frank; Panet, Isabelle; Pouilloux, Benjamin; Prieur, Pascal; Rebray, Alexandre; Reynaud, Serge; Rievers, Benny; Robert, Alain; Selig, Hanns; Serron, Laura; Sumner, Timothy; Tanguy, Nicolas; Visser, Pieter

2017-12-08

According to the weak equivalence principle, all bodies should fall at the same rate in a gravitational field. The MICROSCOPE satellite, launched in April 2016, aims to test its validity at the 10^{-15} precision level, by measuring the force required to maintain two test masses (of titanium and platinum alloys) exactly in the same orbit. A nonvanishing result would correspond to a violation of the equivalence principle, or to the discovery of a new long-range force. Analysis of the first data gives δ(Ti,Pt)=[-1±9(stat)±9(syst)]×10^{-15} (1σ statistical uncertainty) for the titanium-platinum Eötvös parameter characterizing the relative difference in their free-fall accelerations.

Gravity's Rainbow

NASA Image and Video Library

2018-04-23

Saturn's rings display their subtle colors in this view captured on Aug. 22, 2009, by NASA's Cassini spacecraft. The particles that make up the rings range in size from smaller than a grain of sand to as large as mountains, and are mostly made of water ice. The exact nature of the material responsible for bestowing color on the rings remains a matter of intense debate among scientists. Images taken using red, green and blue spectral filters were combined to create this natural color view. Cassini's narrow-angle camera took the images at a distance of approximately 1.27 million miles (2.05 million kilometers) from the center of the rings. The Cassini spacecraft ended its mission on Sept. 15, 2017 https://photojournal.jpl.nasa.gov/catalog/PIA22418

Exact nonlinear command generation and tracking for robot manipulators and spacecraft slewing maneuvers

NASA Technical Reports Server (NTRS)

Dywer, T. A. W., III; Lee, G. K. F.

1984-01-01

In connection with the current interest in agile spacecraft maneuvers, it has become necessary to consider the nonlinear coupling effects of multiaxial rotation in the treatment of command generation and tracking problems. Multiaxial maneuvers will be required in military missions involving a fast acquisition of moving targets in space. In addition, such maneuvers are also needed for the efficient operation of robot manipulators. Attention is given to details regarding the direct nonlinear command generation and tracking, an approach which has been successfully applied to the design of control systems for V/STOL aircraft, linearizing transformations for spacecraft controlled with external thrusters, the case of flexible spacecraft dynamics, examples from robot dynamics, and problems of implementation and testing.

MICROSCOPE Mission: First Results of a Space Test of the Equivalence Principle

NASA Astrophysics Data System (ADS)

Touboul, Pierre; Métris, Gilles; Rodrigues, Manuel; André, Yves; Baghi, Quentin; Bergé, Joël; Boulanger, Damien; Bremer, Stefanie; Carle, Patrice; Chhun, Ratana; Christophe, Bruno; Cipolla, Valerio; Damour, Thibault; Danto, Pascale; Dittus, Hansjoerg; Fayet, Pierre; Foulon, Bernard; Gageant, Claude; Guidotti, Pierre-Yves; Hagedorn, Daniel; Hardy, Emilie; Huynh, Phuong-Anh; Inchauspe, Henri; Kayser, Patrick; Lala, Stéphanie; Lämmerzahl, Claus; Lebat, Vincent; Leseur, Pierre; Liorzou, Françoise; List, Meike; Löffler, Frank; Panet, Isabelle; Pouilloux, Benjamin; Prieur, Pascal; Rebray, Alexandre; Reynaud, Serge; Rievers, Benny; Robert, Alain; Selig, Hanns; Serron, Laura; Sumner, Timothy; Tanguy, Nicolas; Visser, Pieter

2017-12-01

According to the weak equivalence principle, all bodies should fall at the same rate in a gravitational field. The MICROSCOPE satellite, launched in April 2016, aims to test its validity at the 10-15 precision level, by measuring the force required to maintain two test masses (of titanium and platinum alloys) exactly in the same orbit. A nonvanishing result would correspond to a violation of the equivalence principle, or to the discovery of a new long-range force. Analysis of the first data gives δ (Ti ,Pt )=[-1 ±9 (stat)±9 (syst)]×10-15 (1 σ statistical uncertainty) for the titanium-platinum Eötvös parameter characterizing the relative difference in their free-fall accelerations.

Pragmatic open space box utilization: asteroid survey model using distributed objects management based articulation (DOMBA)

NASA Astrophysics Data System (ADS)

Mohammad, Atif Farid; Straub, Jeremy

2015-05-01

A multi-craft asteroid survey has significant data synchronization needs. Limited communication speeds drive exacting performance requirements. Tables have been used in Relational Databases, which are structure; however, DOMBA (Distributed Objects Management Based Articulation) deals with data in terms of collections. With this, no read/write roadblocks to the data exist. A master/slave architecture is created by utilizing the Gossip protocol. This facilitates expanding a mission that makes an important discovery via the launch of another spacecraft. The Open Space Box Framework facilitates the foregoing while also providing a virtual caching layer to make sure that continuously accessed data is available in memory and that, upon closing the data file, recharging is applied to the data.

Recent and upcoming observations of the CARacterisation et Modelisation de l'ENvironnement (CARMEN) mission

NASA Astrophysics Data System (ADS)

Ecoffet, Robert; Maget, Vincent; Rolland, Guy; Lorfevre, Eric; Bourdarie, Sébastien; Boscher, Daniel

2016-07-01

We have developed a series of instruments for energetic particle measurements, associated with component test beds "MEX". The aim of this program is to check and improve space radiation engineering models and techniques. The first series of instruments, "ICARE" has flown on the MIR space station (SPICA mission), the ISS (SPICA-S mission) and the SAC-C low Earth polar orbiting satellite (ICARE mission 2001-2011) in cooperation with the Argentinian space agency CONAE. A second series of instruments "ICARE-NG" was and is flown as: - CARMEN-1 mission on CONAE's SAC-D, 650 km, 98°, 2011-2015, along with three "SODAD" space micro-debris detectors - CARMEN-2 mission on the JASON-2 satellite (CNES, JPL, EUMETSAT, NOAA), 1336 km, 66°, 2008-now, along with JAXA's LPT energetic particle detector - CARMEN-3 mission on the JASON-3 satellite in the same orbit as JASON-2, launched 17 January 2016, along with a plasma detector "AMBRE", and JAXA's LPT again. The ICARE-NG is spectrometer composed of a set of three fully depleted silicon solid state detectors used in single and coincident mode. The on-board measurements consist in accumulating energy loss spectra in the detectors over a programmable accumulation period. The spectra are generated through signal amplitude classification using 8 bit ADCs and resulting in 128/256 channels histograms. The discriminators reference levels, amplifier gain and accumulation time for the spectra are programmable to provide for possible on-board tuning optimization. Ground level calibrations have been made at ONERA-DESP using radioactive source emitting alpha particles in order to determine the exact correspondence between channel number and particle energy. To obtain the response functions to particles, a detailed sectoring analysis of the satellite associated with GEANT-4/MCNP-X calculations has been performed to characterize the geometrical factors of the each detector for p+ as well as for e- with different energies. The component test bed "MEX" is equipped with two different types of active dosimeters, P-MOS silicon dosimeters and OSL (optically stimulated luminescence). Those dosimeters provide independent measurements of ionizing and displacement damage doses and consolidate spectrometers' observations. The data sets obtained cover more than one solar cycle. Dynamics of the radiation belts, effects of solar particle events, coronal mass ejections and coronal holes were observed. Spectrometer measurements and dosimeter readings were used to evaluate current engineering models, and helped in developing improved ones, along with "space weather" radiation belt indices. The presentation will provide a comprehensive review of detector features and mission results.

A Mission Control Architecture for robotic lunar sample return as field tested in an analogue deployment to the sudbury impact structure

NASA Astrophysics Data System (ADS)

Moores, John E.; Francis, Raymond; Mader, Marianne; Osinski, G. R.; Barfoot, T.; Barry, N.; Basic, G.; Battler, M.; Beauchamp, M.; Blain, S.; Bondy, M.; Capitan, R.-D.; Chanou, A.; Clayton, J.; Cloutis, E.; Daly, M.; Dickinson, C.; Dong, H.; Flemming, R.; Furgale, P.; Gammel, J.; Gharfoor, N.; Hussein, M.; Grieve, R.; Henrys, H.; Jaziobedski, P.; Lambert, A.; Leung, K.; Marion, C.; McCullough, E.; McManus, C.; Neish, C. D.; Ng, H. K.; Ozaruk, A.; Pickersgill, A.; Preston, L. J.; Redman, D.; Sapers, H.; Shankar, B.; Singleton, A.; Souders, K.; Stenning, B.; Stooke, P.; Sylvester, P.; Tornabene, L.

2012-12-01

A Mission Control Architecture is presented for a Robotic Lunar Sample Return Mission which builds upon the experience of the landed missions of the NASA Mars Exploration Program. This architecture consists of four separate processes working in parallel at Mission Control and achieving buy-in for plans sequentially instead of simultaneously from all members of the team. These four processes were: science processing, science interpretation, planning and mission evaluation. science processing was responsible for creating products from data downlinked from the field and is organized by instrument. Science Interpretation was responsible for determining whether or not science goals are being met and what measurements need to be taken to satisfy these goals. The Planning process, responsible for scheduling and sequencing observations, and the Evaluation process that fostered inter-process communications, reporting and documentation assisted these processes. This organization is advantageous for its flexibility as shown by the ability of the structure to produce plans for the rover every two hours, for the rapidity with which Mission Control team members may be trained and for the relatively small size of each individual team. This architecture was tested in an analogue mission to the Sudbury impact structure from June 6-17, 2011. A rover was used which was capable of developing a network of locations that could be revisited using a teach and repeat method. This allowed the science team to process several different outcrops in parallel, downselecting at each stage to ensure that the samples selected for caching were the most representative of the site. Over the course of 10 days, 18 rock samples were collected from 5 different outcrops, 182 individual field activities - such as roving or acquiring an image mosaic or other data product - were completed within 43 command cycles, and the rover travelled over 2200 m. Data transfer from communications passes were filled to 74%. Sample triage was simulated to allow down-selection to 1 kg of material for return to Earth.

Advanced timeline systems

NASA Technical Reports Server (NTRS)

Bulfin, R. L.; Perdue, C. A.

1994-01-01

The Mission Planning Division of the Mission Operations Laboratory at NASA's Marshall Space Flight Center is responsible for scheduling experiment activities for space missions controlled at MSFC. In order to draw statistically relevant conclusions, all experiments must be scheduled at least once and may have repeated performances during the mission. An experiment consists of a series of steps which, when performed, provide results pertinent to the experiment's functional objective. Since these experiments require a set of resources such as crew and power, the task of creating a timeline of experiment activities for the mission is one of resource constrained scheduling. For each experiment, a computer model with detailed information of the steps involved in running the experiment, including crew requirements, processing times, and resource requirements is created. These models are then loaded into the Experiment Scheduling Program (ESP) which attempts to create a schedule which satisfies all resource constraints. ESP uses a depth-first search technique to place each experiment into a time interval, and a scoring function to evaluate the schedule. The mission planners generate several schedules and choose one with a high value of the scoring function to send through the approval process. The process of approving a mission timeline can take several months. Each timeline must meet the requirements of the scientists, the crew, and various engineering departments as well as enforce all resource restrictions. No single objective is considered in creating a timeline. The experiment scheduling problem is: given a set of experiments, place each experiment along the mission timeline so that all resource requirements and temporal constraints are met and the timeline is acceptable to all who must approve it. Much work has been done on multicriteria decision making (MCDM). When there are two criteria, schedules which perform well with respect to one criterion will often perform poorly with respect to the other. One schedule dominates another if it performs strictly better on one criterion, and no worse on the other. Clearly, dominated schedules are undesireable. A nondominated schedule can be generated by some sort of optimization problem. Generally there are two approaches: the first is a hierarchical approach while the second requires optimizing a weighting or scoring function.

Europe's latest space telescope is off to a good start

NASA Astrophysics Data System (ADS)

1999-12-01

The world's most powerful observatory for X-ray astronomy, the European Space Agency's XMM satellite, set off into space from Kourou, French Guiana, at 15:32 Paris time on 10 December. The mighty Ariane 5 launcher, making its very first commercial launch, hurled the 3.9-tonne spacecraft into a far-ranging orbit. Within one hour of lift-off the European Space Operations Centre at Darmstadt, Germany, confirmed XMM was under control with electrical power available from the solar arrays. "XMM is the biggest and most innovative scientific spacecraft developed by ESA so far," said Roger Bonnet, ESA's Director of Science. "The world's space agencies now want the new technology that ESA and Europe's industries have put into XMM's amazingly sensitive X-ray telescopes. And the world's astronomers are queuing up to use XMM to explore the hottest places in the universe. We must ask them to be patient while we get XMM fully commissioned." XMM's initial orbit carries it far into space, to 114,000 kilometres from the Earth at its most distant point. On its return the satellite's closest approach, or perigee, will be at 850 kilometres. The next phase of the operation, expected to take about a week, will raise that perigee to 7000 kilometres by repeated firing of XMM's own thrusters. The spacecraft will then be on its intended path, spending 40 hours out of every 48-hour orbit clear of the radiation belts which spoil the view of the X-ray universe. Technical commissioning and verification of the performance of the telescopes and scientific instruments will then follow. XMM should be fully operational for astronomy in the spring of 2000. All of ESA's science missions present fresh technological challenges to Europe's aerospace industries. In building XMM, the prime contractor Dornier Satellitensysteme in Friedrichshafen in Germany (part of DaimlerChrysler Aerospace) has led an industrial consortium involving 46 companies from 14 European countries and one in the United States. XMM stands for X-ray Multi-Mirror Mission. Its main telescopes will gather X-rays from the cosmos with 120 square metres of gold-coated surfaces, in 174 mirrors fashioned, smoothed and nested together with high precision by contractors in Germany and Italy. With XMM, Europe has taken the lead in X-ray missions and X-ray detectors: the most sensitive and largest ever made. The four complex scientific instruments on XMM have been developed and led by European scientists with participation from institutes worldwide. Compared with NASA's Chandra X-ray telescope launched earlier this year, XMM is at least 5 times more sensitive. The gain in sensitivity is 15-fold, at high X-ray energies. But Chandra has a sharper view, so the two missions are complementary and there is close transatlantic collaboration among the scientists involved. Prime scientific objectives for XMM are to find out exactly what goes on in the vicinity of black holes, and to help to clear up the mystery of the stupendous explosions called gamma-ray bursts. Other hot topics for investigation include cannibalism among the stars, the release of newly made chemical elements from stellar explosions, and the origin of the cosmic rays that rain on the Earth. XMM is one of a carefully-planned series of scientific satellites built in Europe by which ESA has established a pioneering role in space astronomy. Recently completed missions include the very successful star-mapping satellite Hipparcos, and the Infrared Space Observatory which revolutionized astronomers' knowledge of the cool parts of the universe. Coming along after XMM are Integral for gamma-ray astronomy, FIRST for the far-infrared, and Planck for examining the entire cosmic microwave background far more accurately than ever before.

A New Monte Carlo Filtering Method for the Diagnosis of Mission-Critical Failures

NASA Technical Reports Server (NTRS)

Gay, Gregory; Menzies, Tim; Davies, Misty; Gundy-Burlet, Karen

2009-01-01

Testing large-scale systems is expensive in terms of both time and money. Running simulations early in the process is a proven method of finding the design faults likely to lead to critical system failures, but determining the exact cause of those errors is still time-consuming and requires access to a limited number of domain experts. It is desirable to find an automated method that explores the large number of combinations and is able to isolate likely fault points. Treatment learning is a subset of minimal contrast-set learning that, rather than classifying data into distinct categories, focuses on finding the unique factors that lead to a particular classification. That is, they find the smallest change to the data that causes the largest change in the class distribution. These treatments, when imposed, are able to identify the settings most likely to cause a mission-critical failure. This research benchmarks two treatment learning methods against standard optimization techniques across three complex systems, including two projects from the Robust Software Engineering (RSE) group within the National Aeronautics and Space Administration (NASA) Ames Research Center. It is shown that these treatment learners are both faster than traditional methods and show demonstrably better results.

KSC-08pd0006

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, Bob Arp, an aerospace technician with the United Launch Alliance, solders a pin to the socket of the replacement feed-through connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technician performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and was specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0004

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, aerospace technicians with the United Launch Alliance inspect an electrical wiring harness that has been inserted into a replacement feed-through connector during preparations to solder the pins to the socket of the connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technicians performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and were specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0001

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, a Lockheed Martin technician prepares an electrical wiring harness during a procedure to solder the pins to the socket of the replacement feed-through connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. Two United Launch Alliance technicians, who performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994, will be doing the soldering. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0009

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, Bob Arp, an aerospace technician with the United Launch Alliance, examinies the pins remaining to be soldered to the socket of the replacement feed-through connector that will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technician performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and was specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0003

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, Kevin Wyckoff, an aerospace technician with the United Launch Alliance, inserts an electrical wiring harness into a replacement feed-through connector during preparations to solder the pins to the socket of the connector. The connector will later be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technician performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and was specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

LUNAR MODULE TEST ARTICLE [LTA] [2R] IS MOVED FOR MATING TO LUNAR MODULE ADAPTER

NASA Technical Reports Server (NTRS)

1967-01-01

The Lunar Module Test Article [LTA] 2R, for the second Saturn V mission, is being moved from the low bay of the Manned Spacecraft Operations Building for mating with the spacecraft Lunar Module Adapter. The second Saturn V [502], except for a different lunar return trajectory, will be a repeat of the Apollo 4 unmanned Earth orbital flight of a high apogee for systems testing using several propulsion system burns and a heat shield test at lunar re-entry speed.

S-191 sensor performance evaluation

NASA Technical Reports Server (NTRS)

Hughes, C. L.

1975-01-01

A final analysis was performed on the Skylab S-191 spectrometer data received from missions SL-2, SL-3, and SL-4. The repeatability and accuracy of the S-191 spectroradiometric internal calibration was determined by correlation to the output obtained from well-defined external targets. These included targets on the moon and earth as well as deep space. In addition, the accuracy of the S-191 short wavelength autocalibration was flight checked by correlation of the earth resources experimental package S-191 outputs and the Backup Unit S-191 outputs after viewing selected targets on the moon.

SERT 2 hollow cathode multiple restarts in space

NASA Technical Reports Server (NTRS)

Kerslake, W. R.; Finke, R. C.

1973-01-01

Future missions, both station keeping and primary electric propulsion, will require multiple thrust restarts after periods of inactivity from a few hours to over one year. Although not a part of the original SERT 2 (Space Electric Rocket Test) flight objective, the opportunity to demonstrate multiple cathode restarts in space became available following completion of thruster running. Both neutralizer and main cathodes of each flight thruster were restarted repeatedly following storage periods up to 490 days. No deterioration of cathode heaters was noted nor was any change required in starting voltages or currents.

Short-term Changes of Apparent Optical Properties in a Shallow Water Environment: Observations from Repeated Airborne Hyperspectral Measurements

NASA Astrophysics Data System (ADS)

Zhang, M.; English, D. C.; Hu, C.; Carlson, P. R., Jr.; Muller-Karger, F. E.; Toro-Farmer, G.; Herwitz, S. R.

2016-02-01

An atmospheric correction algorithm has been developed for AISA imagery over optically shallow waters in Sugarloaf Key of the Florida Keys. The AISA data were collected repeatedly during several days in May 2012, October 2012, and May 2013. A non-zero near-infrared (NIR) remote sensing reflectance (Rrs) was accounted for through iterations, based on the relationship of field-measured Rrs between the NIR and red wavelengths. Validation showed mean ratios of 0.94 to 1.002 between AISA-derived and field-measured Rrs in the blue to red wavelengths, with uncertainties generally < 0.002 sr-1. Such an approach led to observations of diurnal changes of AISA-derived Rrs from repeated measurements over waters with bottom types of seagrass meadow, sand, and patch reef, which were driven by tides and/or winds depending on the bottom types. Rrs generally increased with decreasing tidal height and increasing wind speed, with more changes observed over sandy bottom than over seagrass as explained by changes in water turbidity (light attenuation) and bottom contributions. Some of these changes are larger than two times of the Rrs uncertainties from the AISA retrievals, therefore representing statistically significant changes that can be well observed from airborne measurements. The case study suggests that repeated airborne measurements may be used to study short-term changes in shallow water environments, and such a capacity may be enhanced with future geostationary satellite missions specifically designed to observe coastal ecosystems.

H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development

PubMed Central

Koester-Eiserfunke, Nora; Fischle, Wolfgang

2011-01-01

MBT domain proteins are involved in developmental processes and tumorigenesis. In vitro binding and mutagenesis studies have shown that individual MBT domains within clustered MBT repeat regions bind mono- and dimethylated histone lysine residues with little to no sequence specificity but discriminate against the tri- and unmethylated states. However, the exact function of promiscuous histone methyl-lysine binding in the biology of MBT domain proteins has not been elucidated. Here, we show that the Caenorhabditis elegans four MBT domain protein LIN-61, in contrast to other MBT repeat factors, specifically interacts with histone H3 when methylated on lysine 9, displaying a strong preference for di- and trimethylated states (H3K9me2/3). Although the fourth MBT repeat is implicated in this interaction, H3K9me2/3 binding minimally requires MBT repeats two to four. Further, mutagenesis of residues conserved with other methyl-lysine binding MBT regions in the fourth MBT repeat does not abolish interaction, implicating a distinct binding mode. In vivo, H3K9me2/3 interaction of LIN-61 is required for C. elegans vulva development within the synMuvB pathway. Mutant LIN-61 proteins deficient in H3K9me2/3 binding fail to rescue lin-61 synMuvB function. Also, previously identified point mutant synMuvB alleles are deficient in H3K9me2/3 interaction although these target residues that are outside of the fourth MBT repeat. Interestingly, lin-61 genetically interacts with two other synMuvB genes, hpl-2, an HP1 homologous H3K9me2/3 binding factor, and met-2, a SETDB1 homologous H3K9 methyl transferase (H3K9MT), in determining C. elegans vulva development and fertility. Besides identifying the first sequence specific and di-/trimethylation binding MBT domain protein, our studies imply complex multi-domain regulation of ligand interaction of MBT domains. Our results also introduce a mechanistic link between LIN-61 function and biology, and they establish interplay of the H3K9me2/3 binding proteins, LIN-61 and HPL-2, as well as the H3K9MT MET-2 in distinct developmental pathways. PMID:21437264

The Hitchhiker's Guide to the Outer Solar System

NASA Technical Reports Server (NTRS)

Ono, Masahiro; Quadrelli, Marco; Lantoine, Gregory; Backes, Paul; Lopez Ortega, Alejandro; Grip, Havard; Yen, Chen-Wan; Jewitt, David

2015-01-01

We propose a novel deep space propulsion method called the Comet Hitchhiker. The concept is to perform momentum exchange with small bodies (i.e., asteroid and comet) using an extendable/retrievable tether and a harpoon. Unlike previously proposed tethered fly-by, the use of extendable tether enables to change the relative speed with a target. Hence Hitchhiker would be a prospective means of providing orbit insertion deltaV, particularly for rendezvous missions to small bodies in the outer Solar System such as Kuiper belt objects and Centaurs, which are not easily manageable with chemical propulsion or solar electric propulsion. Furthermore, by applying regenerative brake during a hitchhike maneuver, a Hitchhiker can harvest energy. The stored energy can be used to make a departure from the target by quickly retrieving the tether, which we call a inverse hitchhike maneuver. By repeating hitchhike and inverse Hitchhike maneuvers, a Hitchhiker could perform a mission to rendezvous with multiple targets efficiently, which we call a multi-hitchhike mission. We derive the basic equation of Hitchhiker, namely the Space Hitchhike Equation, which relates the specific strength and mass fraction of tether to achievable ?V. We then perform detailed feasibility analysis through finite element simulations of tether as well as hypervelocity impact simulations of the harpoon using the Adaptive Mesh Refinement Objected-oriented C++ (AMROC) algorithm. The analysis results suggest that a hitchhike maneuver with deltaV = approximately 1.5km/s is feasible with flight proven materials such as Kevlar/Zylon tether and tungsten harpoon. A carbon nanotube tether, combined with diamond harpoon, would enable approximately 10 km/s hitchhike maneuver. Finally, we present two particular mission scenarios for Hitchhiker: Pluto rendezvous and a multi-hitchhike mission to the Themis family asteroids in the main belt.

Sleep Disruption Medical Intervention Forecasting (SDMIF) Module for the Integrated Medical Model

NASA Technical Reports Server (NTRS)

Lewandowski, Beth; Brooker, John; Mallis, Melissa; Hursh, Steve; Caldwell, Lynn; Myers, Jerry

2011-01-01

The NASA Integrated Medical Model (IMM) assesses the risk, including likelihood and impact of occurrence, of all credible in-flight medical conditions. Fatigue due to sleep disruption is a condition that could lead to operational errors, potentially resulting in loss of mission or crew. Pharmacological consumables are mitigation strategies used to manage the risks associated with sleep deficits. The likelihood of medical intervention due to sleep disruption was estimated with a well validated sleep model and a Monte Carlo computer simulation in an effort to optimize the quantity of consumables. METHODS: The key components of the model are the mission parameter program, the calculation of sleep intensity and the diagnosis and decision module. The mission parameter program was used to create simulated daily sleep/wake schedules for an ISS increment. The hypothetical schedules included critical events such as dockings and extravehicular activities and included actual sleep time and sleep quality. The schedules were used as inputs to the Sleep, Activity, Fatigue and Task Effectiveness (SAFTE) Model (IBR Inc., Baltimore MD), which calculated sleep intensity. Sleep data from an ISS study was used to relate calculated sleep intensity to the probability of sleep medication use, using a generalized linear model for binomial regression. A human yes/no decision process using a binomial random number was also factored into sleep medication use probability. RESULTS: These probability calculations were repeated 5000 times resulting in an estimate of the most likely amount of sleep aids used during an ISS mission and a 95% confidence interval. CONCLUSIONS: These results were transferred to the parent IMM for further weighting and integration with other medical conditions, to help inform operational decisions. This model is a potential planning tool for ensuring adequate sleep during sleep disrupted periods of a mission.

The Kepler Data Processing Handbook: A Field Guide to Prospecting for Habitable Worlds

NASA Technical Reports Server (NTRS)

Jenkins, Jon M.

2017-01-01

The Kepler telescope hurtled into orbit in March 2009, initiating NASA's first mission to discover Earth-size planets orbiting Sun-like stars. Kepler simultaneously collected data for approximately 165,000 target stars at a time over its four-year mission, identifying over 4700 planet candidates, over 2300 confirmed or validated planets, and over 2100 eclipsing binaries. While Kepler was designed to discover exoplanets, the long-term, ultrahigh photometric precision measurements it achieved made it a premier observational facility for stellar astrophysics, especially in the field of asteroseismology, and for variable stars, such as RR Lyrae. The Kepler Science Operations Center (SOC) was developed at NASA Ames Research Center to process the data acquired by Kepler from pixel-level calibrations all the way to identifying transiting planet signatures and subjecting them to a suite of diagnostic tests to establish or break confidence in their planetary nature. Detecting small, rocky planets transiting Sun-like stars presents a variety of daunting challenges, including achieving an unprecedented photometric precision of 20 ppm on 6.5-hour timescales, and supporting the science operations, management, processing, and repeated reprocessing of the accumulating data stream. A newly revised and expanded version of the Kepler Data Processing Handbook (KDPH) has been released to support the legacy archival products. The KDPH details the theory, design and performance of the algorithms supporting each data processing step. This paper presents an overview of the KDPH and features illustrations of several key algorithms in the Kepler Science Data Processing Pipeline. Kepler was selected as the 10th mission of the Discovery Program. Funding for this mission is provided by NASA, Science Mission Directorate.

STS-109 Mission Highlights Resource Tape

NASA Astrophysics Data System (ADS)

2002-05-01

This video, Part 2 of 4, shows the activities of the STS-109 crew (Scott Altman, Commander; Duane Carey, Pilot; John Grunsfeld, Payload Commander; Nancy Currie, James Newman, Richard Linnehan, Michael Massimino, Mission Specialists) during flight days 4 and 5. The activities from other flights days can be seen on 'STS-109 Mission Highlights Resource Tape' Part 1 of 4 (internal ID 2002139471), 'STS-109 Mission Highlights Resource Tape' Part 3 of 4 (internal ID 2002139476), and 'STS-109 Mission Highlights Resource Tape' Part 4 of 4 (internal ID 2002137577). The primary activities during these days were EVAs (extravehicular activities) to replace two solar arrays on the HST (Hubble Space Telescope). Footage from flight day 4 records an EVA by Grunsfeld and Linnehan, including their exit from Columbia's payload bay airlock, their stowing of the old HST starboard rigid array on the rigid array carrier in Columbia's payload bay, their attachment of the new array on HST, the installation of a new starboard diode box, and the unfolding of the new array. The pistol grip space tool used to fasten the old array in its new location is shown in use. The video also includes several shots of the HST with Earth in the background. On flight day 5 Newman and Massimino conduct an EVA to change the port side array and diode box on HST. This EVA is very similar to the one on flight day 4, and is covered similarly in the video. A hand operated ratchet is shown in use. In addition to a repeat of the previous tasks, the astronauts change HST's reaction wheel assembly, and because they are ahead of schedule, install installation and lubricate an instrument door on the telescope. The Earth views include a view of Egypt and Israel, with the Nile River, Red Sea, and Mediterranean Sea.

DNA Probe Design for Preflight and Inflight Microbial Monitoring

NASA Technical Reports Server (NTRS)

Fox, George E.

1999-01-01

Crew health is a dominant issue in manned space flight. Microbiological concerns, in particular, have repeatedly emerged as determinants of flight readiness. For example, in at least one case, suspected contamination of the potable water supply nearly forced a launch delay. In another instance, a crew member's urinary tract infection nearly led to early termination of the mission, in part due to the difficulty of accurately diagnosing the nature of the infection in-flight. Microbial problems are an increasing concern with the trend towards longer-duration missions. It is essential to the success of such missions that systems that deliver acceptable quality of air and water during the anticipated lifetime of the spacecraft be available. As mission duration and resupply intervals increase, it will be necessary to rely on advanced life support systems which incorporate both biological and physical-chemical recycling methods for air and water as well as provide food for the crew. It therefore is necessary to develop real-time, robust, in-flight monitoring procedures that are sensitive enough to detect less than 100 CFU (colony forming units) of bacteria per 100 milliliters of water. It would be desirable if the monitoring system could be readily "reprogrammed" to identify specific pathogens if an in-flight incident were to occur. Thus, the monitoring technology must simultaneously detect many organisms of interest, be subject to miniaturization and be highly automated The long range goal of project is to develop such monitoring systems.

Lessons learned from planetary science archiving

NASA Astrophysics Data System (ADS)

Zender, J.; Grayzeck, E.

2006-01-01

The need for scientific archiving of past, current, and future planetary scientific missions, laboratory data, and modeling efforts is indisputable. To quote from a message by G. Santayama carved over the entrance of the US Archive in Washington DC “Those who can not remember the past are doomed to repeat it.” The design, implementation, maintenance, and validation of planetary science archives are however disputed by the involved parties. The inclusion of the archives into the scientific heritage is problematic. For example, there is the imbalance between space agency requirements and institutional and national interests. The disparity of long-term archive requirements and immediate data analysis requests are significant. The discrepancy between the space missions archive budget and the effort required to design and build the data archive is large. An imbalance exists between new instrument development and existing, well-proven archive standards. The authors present their view on the problems and risk areas in the archiving concepts based on their experience acquired within NASA’s Planetary Data System (PDS) and ESA’s Planetary Science Archive (PSA). Individual risks and potential problem areas are discussed based on a model derived from a system analysis done upfront. The major risk for a planetary mission science archive is seen in the combination of minimal involvement by Mission Scientists and inadequate funding. The authors outline how the risks can be reduced. The paper ends with the authors view on future planetary archive implementations including the archive interoperability aspect.

The Global-Scale Observations of the Limb and Disk (GOLD) Mission

NASA Astrophysics Data System (ADS)

Eastes, R. W.; McClintock, W. E.; Burns, A. G.; Anderson, D. N.; Andersson, L.; Codrescu, M.; Correira, J. T.; Daniell, R. E.; England, S. L.; Evans, J. S.; Harvey, J.; Krywonos, A.; Lumpe, J. D.; Richmond, A. D.; Rusch, D. W.; Siegmund, O.; Solomon, S. C.; Strickland, D. J.; Woods, T. N.; Aksnes, A.; Budzien, S. A.; Dymond, K. F.; Eparvier, F. G.; Martinis, C. R.; Oberheide, J.

2017-10-01

The Earth's thermosphere and ionosphere constitute a dynamic system that varies daily in response to energy inputs from above and from below. This system can exhibit a significant response within an hour to changes in those inputs, as plasma and fluid processes compete to control its temperature, composition, and structure. Within this system, short wavelength solar radiation and charged particles from the magnetosphere deposit energy, and waves propagating from the lower atmosphere dissipate. Understanding the global-scale response of the thermosphere-ionosphere ( T-I) system to these drivers is essential to advancing our physical understanding of coupling between the space environment and the Earth's atmosphere. Previous missions have successfully determined how the "climate" of the T-I system responds. The Global-scale Observations of the Limb and Disk (GOLD) mission will determine how the "weather" of the T-I responds, taking the next step in understanding the coupling between the space environment and the Earth's atmosphere. Operating in geostationary orbit, the GOLD imaging spectrograph will measure the Earth's emissions from 132 to 162 nm. These measurements will be used image two critical variables—thermospheric temperature and composition, near 160 km—on the dayside disk at half-hour time scales. At night they will be used to image the evolution of the low latitude ionosphere in the same regions that were observed earlier during the day. Due to the geostationary orbit being used the mission observes the same hemisphere repeatedly, allowing the unambiguous separation of spatial and temporal variability over the Americas.

Detection of possible restriction sites for type II restriction enzymes in DNA sequences.

PubMed

Gagniuc, P; Cimponeriu, D; Ionescu-Tîrgovişte, C; Mihai, Andrada; Stavarachi, Monica; Mihai, T; Gavrilă, L

2011-01-01

In order to make a step forward in the knowledge of the mechanism operating in complex polygenic disorders such as diabetes and obesity, this paper proposes a new algorithm (PRSD -possible restriction site detection) and its implementation in Applied Genetics software. This software can be used for in silico detection of potential (hidden) recognition sites for endonucleases and for nucleotide repeats identification. The recognition sites for endonucleases may result from hidden sequences through deletion or insertion of a specific number of nucleotides. Tests were conducted on DNA sequences downloaded from NCBI servers using specific recognition sites for common type II restriction enzymes introduced in the software database (n = 126). Each possible recognition site indicated by the PRSD algorithm implemented in Applied Genetics was checked and confirmed by NEBcutter V2.0 and Webcutter 2.0 software. In the sequence NG_008724.1 (which includes 63632 nucleotides) we found a high number of potential restriction sites for ECO R1 that may be produced by deletion (n = 43 sites) or insertion (n = 591 sites) of one nucleotide. The second module of Applied Genetics has been designed to find simple repeats sizes with a real future in understanding the role of SNPs (Single Nucleotide Polymorphisms) in the pathogenesis of the complex metabolic disorders. We have tested the presence of simple repetitive sequences in five DNA sequence. The software indicated exact position of each repeats detected in the tested sequences. Future development of Applied Genetics can provide an alternative for powerful tools used to search for restriction sites or repetitive sequences or to improve genotyping methods.

Reperfusion response changes induced by repeated, sustained contractions in normal human masseter muscle.

PubMed

Aizawa, Shigeru; Tsukiyama, Yoshihiro; Koyano, Kiyoshi; Clark, Glenn T

2002-07-01

The purpose was to evaluate the intramuscular reperfusion response characteristics associated with repeated isometric contractions in normal human masseter. Intramuscular blood volume was quantified with a near-infrared spectroscopic device that measured the total haemoglobin (Hb) concentration in the muscle. Electromyographic (EMG) activity from the masseter and total bite forces were also recorded. Sixteen healthy volunteers, eight females and eight males, without masticatory muscle pain participated. They were asked first to clench their teeth for as long as possible at 50% of their maximum voluntary contraction (MVC). This was followed by a 60s rest and then immediately by a standard clenching task (50% MVC for 30s) and a 60s recovery period, immediately after which they were asked to repeat exactly the same procedure, with a final 5 min recovery period after the second 30s contraction. Bite force, EMG and Hb concentration were measured continuously and the duration of the two endurance tasks and the amplitudes of all recorded signals were compared (first trial versus second trial). Specifically, the difference between the lowest Hb (trough) seen during the standardised 30s contractions and the highest (peak) seen just after them was assessed. The trough-to-peak difference in Hb concentration of the second standard contraction task was significantly smaller than that of the first standard task (P<0.05, paired t-test). These data show that with sustained effort the post-contraction vasodilatory reperfusion responses of the human masseter are diminished, suggesting a progressive desensitisation of the vasodilatory system.

Investigation of repeated vaccination as a possible cause of glomerular disease in mink.

PubMed

Newman, Shelley Joy; Johnson, Roger; Sears, William; Wilcock, Brian

2002-07-01

The search for antigens capable of causing immune-complex-mediated glomerulonephritis continues. Modified live-virus vaccines commercially available for veterinary use are a possible source. In this study, repeated vaccination of mink with live-virus vaccines was investigated as a model for vaccine-induced glomerular injury. Three groups of 10-wk-old mink, 15 per group, were vaccinated once with 4-way vaccine against distemper, Pseudomonas aeruginosa infection, botulism and mink viral enteritis. Subsequently, all mink in each group each were vaccinated either with the 4-way vaccine, a monovalent canine distemper vaccine, or saline. Glomerular function was assessed at 2-wk intervals by determining the urinary protein:creatinine (P:C) ratio. Kidney sections taken at necropsy, 20 wk after the 1st vaccination, were examined by light and immunofluorescent microscopy for deposition of immunoglobulin and complement. There was no statistically significant difference between the treated and control groups based on average urinary P:C ratio medians. Light microscopic changes were detected in glomeruli, but Fisher's exact test showed no significant differences between any of the treatment groups. Deposition of immunoglobulin but not complement was significantly more frequent (P < 0.05) in the glomeruli of animals that received multiple injections of the 4-way vaccine than in the glomeruli of those given only the monovalent canine distemper vaccine or saline. These findings suggest that repeated vaccination may increase the glomerular deposition of immunoglobulin. Further studies are required to determine if the increased deposition of immunoglobulin contributes to the development of glomerular damage and to identify the antigens driving production of the deposited immunoglobulin.

The number of measurements needed to obtain high reliability for traits related to enzymatic activities and photosynthetic compounds in soybean plants infected with Phakopsora pachyrhizi.

PubMed

Oliveira, Tássia Boeno de; Azevedo Peixoto, Leonardo de; Teodoro, Paulo Eduardo; Alvarenga, Amauri Alves de; Bhering, Leonardo Lopes; Campo, Clara Beatriz Hoffmann

2018-01-01

Asian rust affects the physiology of soybean plants and causes losses in yield. Repeatability coefficients may help breeders to know how many measurements are needed to obtain a suitable reliability for a target trait. Therefore, the objectives of this study were to determine the repeatability coefficients of 14 traits in soybean plants inoculated with Phakopsora pachyrhizi and to establish the minimum number of measurements needed to predict the breeding value with high accuracy. Experiments were performed in a 3x2 factorial arrangement with three treatments and two inoculations in a random block design. Repeatability coefficients, coefficients of determination and number of measurements needed to obtain a certain reliability were estimated using ANOVA, principal component analysis based on the covariance matrix and the correlation matrix, structural analysis and mixed model. It was observed that the principal component analysis based on the covariance matrix out-performed other methods for almost all traits. Significant differences were observed for all traits except internal CO2 concentration for the treatment effects. For the measurement effects, all traits were significantly different. In addition, significant differences were found for all Treatment x Measurement interaction traits except coumestrol, chitinase and chlorophyll content. Six measurements were suitable to obtain a coefficient of determination higher than 0.7 for all traits based on principal component analysis. The information obtained from this research will help breeders and physiologists determine exactly how many measurements are needed to evaluate each trait in soybean plants infected by P. pachyrhizi with a desirable reliability.

The number of measurements needed to obtain high reliability for traits related to enzymatic activities and photosynthetic compounds in soybean plants infected with Phakopsora pachyrhizi

PubMed Central

de Oliveira, Tássia Boeno; Teodoro, Paulo Eduardo; de Alvarenga, Amauri Alves; Bhering, Leonardo Lopes; Campo, Clara Beatriz Hoffmann

2018-01-01

Asian rust affects the physiology of soybean plants and causes losses in yield. Repeatability coefficients may help breeders to know how many measurements are needed to obtain a suitable reliability for a target trait. Therefore, the objectives of this study were to determine the repeatability coefficients of 14 traits in soybean plants inoculated with Phakopsora pachyrhizi and to establish the minimum number of measurements needed to predict the breeding value with high accuracy. Experiments were performed in a 3x2 factorial arrangement with three treatments and two inoculations in a random block design. Repeatability coefficients, coefficients of determination and number of measurements needed to obtain a certain reliability were estimated using ANOVA, principal component analysis based on the covariance matrix and the correlation matrix, structural analysis and mixed model. It was observed that the principal component analysis based on the covariance matrix out-performed other methods for almost all traits. Significant differences were observed for all traits except internal CO2 concentration for the treatment effects. For the measurement effects, all traits were significantly different. In addition, significant differences were found for all Treatment x Measurement interaction traits except coumestrol, chitinase and chlorophyll content. Six measurements were suitable to obtain a coefficient of determination higher than 0.7 for all traits based on principal component analysis. The information obtained from this research will help breeders and physiologists determine exactly how many measurements are needed to evaluate each trait in soybean plants infected by P. pachyrhizi with a desirable reliability. PMID:29438380

Optimum Number of Anchored Clathrate Water and Its Instantaneous Fluctuations Dictate Ice Plane Recognition Specificities of Insect Antifreeze Protein.

PubMed

Chakraborty, Sandipan; Jana, Biman

2018-03-29

Ice recognition by antifreeze proteins (AFPs) is a subject of topical interest. Among several classes of AFPs, insect AFPs are hyperactive presumably due to their ability to adsorb on basal plane. However, the origin of the basal plane binding specificity is not clearly known. Present work aims to provide atomistic insight into the origin of basal plane recognition by an insect antifreeze protein. Free energy calculations reveal that the order of binding affinity of the AFP toward different ice planes is basal plane > prism plane > pyramidal plane. Critical insight reveals that the observed plane specificity is strongly correlated with the number and their instantaneous fluctuations of clathrate water forming hydrogen bonds with both ice binding surface (IBS) of AFP and ice surface, thus anchoring AFP to the ice surface. On basal plane, anchored clathrate water array is highly stable due to exact match in the periodicity of oxygen atom repeat distances of the ice surface and the threonine repeat distances at the IBS. The stability of anchored clathrate water array progressively decreases upon prism and pyramidal plane adsorption due to mismatch between the threonine ladder and oxygen atom repeat distance. Further analysis reveals that hydration around the methyl side-chains of threonine residues becomes highly significant at low temperature which stabilizes the anchored clathrate water array and dual hydrogen-bonding is a consequence of this stability. Structural insight gained from this study paves the way for rational designing of highly potent antifreeze-mimetic with potential industrial applications.

Universal Recurrence Time Statistics of Characteristic Earthquakes

NASA Astrophysics Data System (ADS)

Goltz, C.; Turcotte, D. L.; Abaimov, S.; Nadeau, R. M.

2006-12-01

Characteristic earthquakes are defined to occur quasi-periodically on major faults. Do recurrence time statistics of such earthquakes follow a particular statistical distribution? If so, which one? The answer is fundamental and has important implications for hazard assessment. The problem cannot be solved by comparing the goodness of statistical fits as the available sequences are too short. The Parkfield sequence of M ≍ 6 earthquakes, one of the most extensive reliable data sets available, has grown to merely seven events with the last earthquake in 2004, for example. Recently, however, advances in seismological monitoring and improved processing methods have unveiled so-called micro-repeaters, micro-earthquakes which recur exactly in the same location on a fault. It seems plausible to regard these earthquakes as a miniature version of the classic characteristic earthquakes. Micro-repeaters are much more frequent than major earthquakes, leading to longer sequences for analysis. Due to their recent discovery, however, available sequences contain less than 20 events at present. In this paper we present results for the analysis of recurrence times for several micro-repeater sequences from Parkfield and adjacent regions. To improve the statistical significance of our findings, we combine several sequences into one by rescaling the individual sets by their respective mean recurrence intervals and Weibull exponents. This novel approach of rescaled combination yields the most extensive data set possible. We find that the resulting statistics can be fitted well by an exponential distribution, confirming the universal applicability of the Weibull distribution to characteristic earthquakes. A similar result is obtained from rescaled combination, however, with regard to the lognormal distribution.

Feed mechanism and method for feeding minute items

DOEpatents

Stringer, Timothy Kent; Yerganian, Simon Scott

2012-11-06

A feeding mechanism and method for feeding minute items, such as capacitors, resistors, or solder preforms. The mechanism is adapted to receive a plurality of the randomly-positioned and randomly-oriented extremely small or minute items, and to isolate, orient, and position the items in a specific repeatable pickup location wherefrom they may be removed for use by, for example, a computer-controlled automated assembly machine. The mechanism comprises a sliding shelf adapted to receive and support the items; a wiper arm adapted to achieve a single even layer of the items; and a pushing arm adapted to push the items into the pickup location. The mechanism can be adapted for providing the items with a more exact orientation, and can also be adapted for use in a liquid environment.

Feed mechanism and method for feeding minute items

DOEpatents

Stringer, Timothy Kent [Bucyrus, KS; Yerganian, Simon Scott [Lee's Summit, MO

2009-10-20

A feeding mechanism and method for feeding minute items, such as capacitors, resistors, or solder preforms. The mechanism is adapted to receive a plurality of the randomly-positioned and randomly-oriented extremely small or minute items, and to isolate, orient, and position one or more of the items in a specific repeatable pickup location wherefrom they may be removed for use by, for example, a computer-controlled automated assembly machine. The mechanism comprises a sliding shelf adapted to receive and support the items; a wiper arm adapted to achieve a single even layer of the items; and a pushing arm adapted to push the items into the pickup location. The mechanism can be adapted for providing the items with a more exact orientation, and can also be adapted for use in a liquid environment.

A draft sequence of the rice genome (Oryza sativa L. ssp. indica).

PubMed

Yu, Jun; Hu, Songnian; Wang, Jun; Wong, Gane Ka-Shu; Li, Songgang; Liu, Bin; Deng, Yajun; Dai, Li; Zhou, Yan; Zhang, Xiuqing; Cao, Mengliang; Liu, Jing; Sun, Jiandong; Tang, Jiabin; Chen, Yanjiong; Huang, Xiaobing; Lin, Wei; Ye, Chen; Tong, Wei; Cong, Lijuan; Geng, Jianing; Han, Yujun; Li, Lin; Li, Wei; Hu, Guangqiang; Huang, Xiangang; Li, Wenjie; Li, Jian; Liu, Zhanwei; Li, Long; Liu, Jianping; Qi, Qiuhui; Liu, Jinsong; Li, Li; Li, Tao; Wang, Xuegang; Lu, Hong; Wu, Tingting; Zhu, Miao; Ni, Peixiang; Han, Hua; Dong, Wei; Ren, Xiaoyu; Feng, Xiaoli; Cui, Peng; Li, Xianran; Wang, Hao; Xu, Xin; Zhai, Wenxue; Xu, Zhao; Zhang, Jinsong; He, Sijie; Zhang, Jianguo; Xu, Jichen; Zhang, Kunlin; Zheng, Xianwu; Dong, Jianhai; Zeng, Wanyong; Tao, Lin; Ye, Jia; Tan, Jun; Ren, Xide; Chen, Xuewei; He, Jun; Liu, Daofeng; Tian, Wei; Tian, Chaoguang; Xia, Hongai; Bao, Qiyu; Li, Gang; Gao, Hui; Cao, Ting; Wang, Juan; Zhao, Wenming; Li, Ping; Chen, Wei; Wang, Xudong; Zhang, Yong; Hu, Jianfei; Wang, Jing; Liu, Song; Yang, Jian; Zhang, Guangyu; Xiong, Yuqing; Li, Zhijie; Mao, Long; Zhou, Chengshu; Zhu, Zhen; Chen, Runsheng; Hao, Bailin; Zheng, Weimou; Chen, Shouyi; Guo, Wei; Li, Guojie; Liu, Siqi; Tao, Ming; Wang, Jian; Zhu, Lihuang; Yuan, Longping; Yang, Huanming

2002-04-05

We have produced a draft sequence of the rice genome for the most widely cultivated subspecies in China, Oryza sativa L. ssp. indica, by whole-genome shotgun sequencing. The genome was 466 megabases in size, with an estimated 46,022 to 55,615 genes. Functional coverage in the assembled sequences was 92.0%. About 42.2% of the genome was in exact 20-nucleotide oligomer repeats, and most of the transposons were in the intergenic regions between genes. Although 80.6% of predicted Arabidopsis thaliana genes had a homolog in rice, only 49.4% of predicted rice genes had a homolog in A. thaliana. The large proportion of rice genes with no recognizable homologs is due to a gradient in the GC content of rice coding sequences.

Electronic Entanglement Concentration for the Concatenated Greenberger-Horne-Zeilinger State

NASA Astrophysics Data System (ADS)

Ding, Shang-Ping; Zhou, Lan; Gu, Shi-Pu; Wang, Xing-Fu; Sheng, Yu-Bo

2017-06-01

Concatenated Greenberger-Horne-Zeilinger (C-GHZ) state, which encodes many physical qubits in a logic qubit will have important applications in both quantum communication and computation. In this paper, we will describe an entanglement concentration protocol (ECP) for electronic C-GHZ state, by exploiting the electronic polarization beam splitters (PBSs) and charge detection. This protocol has several advantages. First, the parties do not need to know the exact coefficients of the initial less-entangled C-GHZ state, which makes this protocol feasible. Second, with the help of charge detection, the distilled maximally entangled C-GHZ state can be remained for future application. Third, this protocol can be repeated to obtain a higher success probability. We hope that this protocol can be useful in future quantum computation based on electrons.

Deep brain stimulation of the anterior limb of the internal capsule for treatment of therapy-refractory obsessive compulsive disorder (OCD): a case study highlighting neurocognitive and psychiatric changes.

PubMed

Choudhury, Tabina K; Davidson, Joyce E; Viswanathan, Ashwin; Strutt, Adriana M

2017-04-01

Obsessive compulsive disorder (OCD) is an anxiety disorder characterized by repeated, unwanted thoughts and behaviors. Individuals with this condition often experience significant emotional distress secondary to their symptoms. Additionally, impairments in attention/concentration, processing speed, and executive functions are typically observed. The exact pathology of OCD remains unknown; consequently, it can be difficult to treat patients with severe symptomatology. Deep brain stimulation (DBS) may be a viable treatment option for individuals who do not respond to medication and/or cognitive behavioral therapy. The following case discusses DBS of the anterior limb of the internal capsule for a patient with severe, therapy-refractory OCD, including pre- to postoperative neurocognitive and psychiatric changes.

The 3.5 micron light curves of long period variable stars. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Strecker, D. W.

1973-01-01

Infrared observations at an effective wavelength of 3.5 microns of a selected group of long period variable (LPV) stars are presented. Mira type and semiregular stars of M, S, and C spectral classifications were monitored throughout the full cycle of variability. Although the variable infrared radiation does not exactly repeat in intensity or time, the regularity is sufficient to produce mean 3.5 micron light curves. The 3.5 micron maximum radiation lags the visual maximum by about one-seventh of a cycle, while the minimum 3.5 micron intensity occurs nearly one-half cycle after infrared maximum. In some stars, there are inflections or humps on the ascending portion of the 3.5 micron light curve which may also be seen in the visual variations.

Low-Cost, Class D Testing of Spacecraft Photovoltaic Systems Can Reduce Risk

NASA Technical Reports Server (NTRS)

Forgione, Joshua B.; Kojima, Gilbert K.; Hanel, Robert; Mallinson, Mark

2014-01-01

The end-to-end verification of a spacecraft photovoltaic power generation system requires light! A lowcost, portable, and end-to-end photovoltaic-system test appropriate for NASA's new generation of Class D missions is presented. High risk, low-cost, and quick-turn satellites rarely have the resources to execute the traditional approaches from higher-class (A-C) missions. The Class D approach, as demonstrated on the Lunar Atmospheric and Dust Environment Explorer (LADEE), utilizes a portable, metalhalide, theatre lamp for an end-to-end photovoltaic system test. While not as precise and comprehensive as the traditional Large Area Pulsed Solar Simulator (LAPSS) test, the LADEE method leverages minimal resources into an ongoing assessment program that can be applied through numerous stages of the mission. The project takes a true Class D approach in assessing the technical value of a costly, highfidelity performance test versus a simpler approach with less programmatic risk. The resources required are a fraction of that for a LAPSS test, and is easy to repeat due to its portability. Further, the test equipment can be handed down to future projects without building an on-site facility. At the vanguard of Class D missions, the LADEE team frequently wrestled with and challenged the status quo. The philosophy of risk avoidance at all cost, typical to Class A-C missions, simply could not be executed. This innovative and simple testing solution is contextualized to NASA Class D programs and a specific risk encountered during development of the LADEE Electrical Power System (EPS). Selection of the appropriate lamp and safety concerns are discussed, with examples of test results. Combined with the vendor's panellevel data and periodic inspection, the method ensures system integrity from Integration and Test (I&T) through launch. Following launch, mission operations tools are utilized to assess system performance based on a scant amount of available data.

Recovering the time-variable gravitational field using satellite gradiometry: requirements and gradiometer concept

NASA Astrophysics Data System (ADS)

Douch, Karim; Müller, Jürgen; Heinzel, Gerhard; Wu, Hu

2017-04-01

The successful GRACE mission and its far-reaching benefits have highlighted the interest to continue and extend the mapping of the Earth's time-variable gravitational field with follow-on missions and ideally a higher spatiotemporal resolution. Here, we would like to put forward satellite gravitational gradiometry as an alternative solution to satellite-to-satellite tracking for future missions. Besides the higher sensitivity to smaller scales compared to GRACE-like missions, a gradiometry mission would only require one satellite and would provide a direct estimation of a functional of the gravitational field. GOCE, the only gradiometry mission launched so far, was not sensitive enough to map the time-variable part of the gravity field. However, the unprecedented precision of the state-of-the-art optical metrology system on-board the LISA PATHFINDER satellite has opened the way to more performant space inertial sensors. We will therefore examine whether it is technically possible to go beyond GOCE performances and to quantify to what extent the time-variable gravitational field could be determined. First, we derive the requirements on the knowledge of the attitude and the position of the satellite and on the measured gradients in terms of sensitivity and calibration accuracy for a typical repeat low-orbit. We conclude in particular that a noise level smaller than 0.1 mE/√Hz- is required in the measurement bandwidth [5x10-4 ; 10-2]Hz so as to be sensitive to the time-variable gravity signal. We introduce then the design and characteristics of the new gradiometer concept and give an assessment of its noise budget. Contrary to the GOCE electrostatic gradiometer, the position of the test-mass in the accelerometer is measured here by laser interferometry rather than by a capacitive readout system, which improves the overall measurement chain. Finally, the first results of a performance analysis carried out thanks to an end-to-end simulator are discussed and compared to the previously defined requirements.

Solar EUV Irradiance Measurements by the Auto-Calibrating EUV Spectrometers (SolACES) Aboard the International Space Station (ISS)

NASA Astrophysics Data System (ADS)

Schmidtke, G.; Nikutowski, B.; Jacobi, C.; Brunner, R.; Erhardt, C.; Knecht, S.; Scherle, J.; Schlagenhauf, J.

2014-05-01

SolACES is part of the ESA SOLAR ISS mission that started aboard the shuttle mission STS-122 on 7 February 2008. The instrument has recorded solar extreme ultraviolet (EUV) irradiance from 16 to 150 nm during the extended solar activity minimum and the beginning solar cycle 24 with rising solar activity and increasingly changing spectral composition. The SOLAR mission has been extended from a period of 18 months to > 8 years until the end of 2016. SolACES is operating three grazing incidence planar grating spectrometers and two three-current ionization chambers. The latter ones are considered as primary radiometric detector standards. Re-filling the ionization chambers with three different gases repeatedly and using overlapping band-pass filters, the absolute EUV fluxes are derived in these spectral intervals. This way the serious problem of continuing efficiency changes in space-borne instrumentation is overcome during the mission. Evaluating the three currents of the ionization chambers, the overlapping spectral ranges of the spectrometers and of the filters plus inter-comparing the results from the EUV photon absorption in the gases with different absorption cross sections, there are manifold instrumental possibilities to cross-check the results providing a high degree of reliability to the spectral irradiance derived. During the mission a very strong up-and-down variability of the spectrometric efficiency by orders of magnitude is observed. One of the effects involved is channeltron degradation. However, there are still open questions on other effects contributing to these changes. A survey of the measurements carried out and first results of the solar spectral irradiance (SSI) data are presented. Inter-comparison with EUV data from other space missions shows good agreement such that the international effort has started to elaborate a complete set of EUV-SSI data taking into account all data available from 2008 to 2013.

Is international volunteer surgery for cleft lip and cleft palate a cost-effective and justifiable intervention? A case study from East Asia.

PubMed

Moon, Woori; Perry, Henry; Baek, Rong-Min

2012-12-01

Although surgery provided by international volunteers is increasingly common in the developing world, there have been few assessments of the cost-effectiveness of these activities. In this context, this study covered 15 years of experience of one international nongovernmental organization, Smile for Children, in providing cleft lip (CL) and cleft palate (CP) surgical services in Vietnam. We analyzed the cost-effectiveness of the program and its contributions to building local capacity. To assess the cost-effectiveness of CL/CP surgery performed during Smile for Children's missions in Vietnam, we analyzed the data from four annual missions, from 2007 to 2010. According to the 2003 World Health Organization Guide to Cost-Effectiveness Analysis, we calculated cost per disability-adjusted life years (DALYs) averted with and without age weighting. For the data from the 2010 mission, we repeated the same calculation but with and without considering opportunity cost for labor. The discounted cost per DALY averted averaged $68, ranging from $52 to $79 depending on the year of the mission. The average discounted cost per DALY averted with age weighting was $56 (range $43-$65). For the calculation that takes into account the volunteers' possible income loss as the labor cost of the mission in 2010, the cost per DALY averted without age weighting increased by 28%, from $76 to $97; and the cost per DALY averted with age weighting increased by 27%, from $63 to $80. Under all of these varying assumptions, the CL/CP program operated by Smile for Children is a cost-effective intervention using international criteria for cost-effectiveness. The contribution of the international volunteer surgical team to building in-country capacity is notable. It was achieved primarily through training Vietnamese surgeons during the mission trips and through sending these surgeons to Korea for training. Other staff, including anesthesiologists, were also trained; and equipment and supplies were provided.

Ikhana: A NASA UAS Supporting Long Duration Earth Science Missions

NASA Technical Reports Server (NTRS)

Cobleigh, Brent R.

2006-01-01

NASA's Ikhana unmanned aerial vehicle (UAV) is a General Atomics MQ-9 Predator-B modified to support the conduct of Earth science missions for the NASA Science Mission Directorate through partnerships, other government agencies and universities. Ikhana, a Native American word meaning 'intelligence', can carry over 2000 lbs of atmospheric and remote sensing instruments in the payload bay and external pods. The aircraft is capable of mission durations in excess of 24 hours at altitudes above 40,000 ft. Redundant flight control, avionics, power, and network systems increase the system reliability and allow easier access to public airspace. The aircraft is remotely piloted from a mobile ground control station (GCS) using both C-band line-of-sight and Ku-band over-the-horizon satellite datalinks. NASA's GCS has been modified to support on-site science monitoring, or the downlink data can be networked to remote sites. All ground support systems are designed to be deployable to support global Eart science investigations. On-board support capabilities include an instrumentation system and an Airborne Research Test System (ARTS). The ARTS can host research algorithms that will autonomously command and control on-board sensors, perform sensor health monitoring, conduct data analysis, and request changes to the flight plan to maximize data collection. The ARTS also has the ability to host algorithms that will autonomously control the aircraft trajectory based on sensor needs, (e.g. precision trajectory for repeat pass interferometry) or to optimize mission objectives (e.g. search for specific atmospheric conditions). Standard on-board networks will collect science data for recording and for inclusion in the aircraft's high bandwidth downlink. The Ikhana project will complete GCS development, science support systems integration, external pod integration and flight clearance, and operations crew training in early 2007. A large-area remote sensing mission is currently scheduled for the Summer 2007.

Oxidative Lung Damage Resulting from Repeated Exposure to Radiation and Hyperoxia Associated with Space Exploration.

PubMed

Pietrofesa, Ralph A; Turowski, Jason B; Arguiri, Evguenia; Milovanova, Tatyana N; Solomides, Charalambos C; Thom, Stephen R; Christofidou-Solomidou, Melpo

2013-09-30

Spaceflight missions may require crewmembers to conduct Extravehicular Activities (EVA) for repair, maintenance or scientific purposes. Pre-breathe protocols in preparation for an EVA entail 100% hyperoxia exposure that may last for a few hours (5-8 hours), and may be repeated 2-3 times weekly. Each EVA is associated with additional challenges such as low levels of total body cosmic/galactic radiation exposure that may present a threat to crewmember health and therefore, pose a threat to the success of the mission. We have developed a murine model of combined, hyperoxia and radiation exposure (double-hit) in the context of evaluating countermeasures to oxidative lung damage associated with space flight. In the current study, our objective was to characterize the early and chronic effects of repeated single and double-hit challenge on lung tissue using a novel murine model of repeated exposure to low-level total body radiation and hyperoxia. This is the first study of its kind evaluating lung damage relevant to space exploration in a rodent model. Mouse cohorts (n=5-15/group) were exposed to repeated: a) normoxia; b) >95% O 2 (O 2 ); c) 0.25Gy single fraction gamma radiation (IR); or d) a combination of O 2 and IR (O 2 +IR) given 3 times per week for 4 weeks. Lungs were evaluated for oxidative damage, active TGFβ1 levels, cell apoptosis, inflammation, injury, and fibrosis at 1, 2, 4, 8, 12, 16, and 20 weeks post-initiation of exposure. Mouse cohorts exposed to all challenge conditions displayed decreased bodyweight compared to untreated controls at 4 and 8 weeks post-challenge initiation. Chronic oxidative lung damage to lipids (malondialdehyde levels), DNA (TUNEL, cleaved Caspase 3, cleaved PARP positivity) leading to apoptotic cell death and to proteins (nitrotyrosine levels) was elevated all treatment groups. Importantly, significant systemic oxidative stress was also noted at the late phase in mouse plasma, BAL fluid, and urine. Importantly, however, late oxidative damage across all parameters that we measured was significantly higher than controls in all cohorts but was exacerbated by the combined exposure to O 2 and IR. Additionally, impaired levels of arterial blood oxygenation were noted in all exposure cohorts. Significant but transient elevation of lung tissue fibrosis ( p <0.05), determined by lung hydroxyproline content, was detected as early as 2 week in mice exposed to challenge conditions and persisted for 4-8 weeks only. Interestingly, active TGFβ1 levels in +BAL fluid was also transiently elevated during the exposure time only (1-4 weeks). Inflammation and lung edema/lung injury was also significantly elevated in all groups at both early and late time points, especially the double-hit group. We have characterized significant, early and chronic lung changes consistent with oxidative tissue damage in our murine model of repeated radiation and hyperoxia exposure relevant to space travel. Lung tissue changes, detectable several months after the original exposure, include significant oxidative lung damage (lipid peroxidation, DNA damage and protein nitrosative stress) and increased pulmonary fibrosis. These findings, along with increased oxidative stress in diverse body fluids and the observed decreases in blood oxygenation levels in all challenge conditions (whether single or in combination), lead us to conclude that in our model of repeated exposure to oxidative stressors, chronic tissue changes are detected that persist even months after the exposure to the stressor has ended. This data will provide useful information in the design of countermeasures to tissue oxidative damage associated with space exploration.

Oxidative Lung Damage Resulting from Repeated Exposure to Radiation and Hyperoxia Associated with Space Exploration

PubMed Central

Pietrofesa, Ralph A; Turowski, Jason B; Arguiri, Evguenia; Milovanova, Tatyana N; Solomides, Charalambos C; Thom, Stephen R; Christofidou-Solomidou, Melpo

2013-01-01

Background Spaceflight missions may require crewmembers to conduct Extravehicular Activities (EVA) for repair, maintenance or scientific purposes. Pre-breathe protocols in preparation for an EVA entail 100% hyperoxia exposure that may last for a few hours (5-8 hours), and may be repeated 2-3 times weekly. Each EVA is associated with additional challenges such as low levels of total body cosmic/galactic radiation exposure that may present a threat to crewmember health and therefore, pose a threat to the success of the mission. We have developed a murine model of combined, hyperoxia and radiation exposure (double-hit) in the context of evaluating countermeasures to oxidative lung damage associated with space flight. In the current study, our objective was to characterize the early and chronic effects of repeated single and double-hit challenge on lung tissue using a novel murine model of repeated exposure to low-level total body radiation and hyperoxia. This is the first study of its kind evaluating lung damage relevant to space exploration in a rodent model. Methods Mouse cohorts (n=5-15/group) were exposed to repeated: a) normoxia; b) >95% O2 (O2); c) 0.25Gy single fraction gamma radiation (IR); or d) a combination of O2 and IR (O2+IR) given 3 times per week for 4 weeks. Lungs were evaluated for oxidative damage, active TGFβ1 levels, cell apoptosis, inflammation, injury, and fibrosis at 1, 2, 4, 8, 12, 16, and 20 weeks post-initiation of exposure. Results Mouse cohorts exposed to all challenge conditions displayed decreased bodyweight compared to untreated controls at 4 and 8 weeks post-challenge initiation. Chronic oxidative lung damage to lipids (malondialdehyde levels), DNA (TUNEL, cleaved Caspase 3, cleaved PARP positivity) leading to apoptotic cell death and to proteins (nitrotyrosine levels) was elevated all treatment groups. Importantly, significant systemic oxidative stress was also noted at the late phase in mouse plasma, BAL fluid, and urine. Importantly, however, late oxidative damage across all parameters that we measured was significantly higher than controls in all cohorts but was exacerbated by the combined exposure to O2 and IR. Additionally, impaired levels of arterial blood oxygenation were noted in all exposure cohorts. Significant but transient elevation of lung tissue fibrosis (p<0.05), determined by lung hydroxyproline content, was detected as early as 2 week in mice exposed to challenge conditions and persisted for 4-8 weeks only. Interestingly, active TGFβ1 levels in +BAL fluid was also transiently elevated during the exposure time only (1-4 weeks). Inflammation and lung edema/lung injury was also significantly elevated in all groups at both early and late time points, especially the double-hit group. Conclusion We have characterized significant, early and chronic lung changes consistent with oxidative tissue damage in our murine model of repeated radiation and hyperoxia exposure relevant to space travel. Lung tissue changes, detectable several months after the original exposure, include significant oxidative lung damage (lipid peroxidation, DNA damage and protein nitrosative stress) and increased pulmonary fibrosis. These findings, along with increased oxidative stress in diverse body fluids and the observed decreases in blood oxygenation levels in all challenge conditions (whether single or in combination), lead us to conclude that in our model of repeated exposure to oxidative stressors, chronic tissue changes are detected that persist even months after the exposure to the stressor has ended. This data will provide useful information in the design of countermeasures to tissue oxidative damage associated with space exploration. PMID:24358450

DNAGear--a free software for spa type identification in Staphylococcus aureus.

PubMed

AL-Tam, Faroq; Brunel, Anne-Sophie; Bouzinbi, Nicolas; Corne, Philippe; Bañuls, Anne-Laure; Shahbazkia, Hamid Reza

2012-11-19

Staphylococcus aureus is both human commensal and an important human pathogen, responsible for community-acquired and nosocomial infections ranging from superficial wound infections to invasive infections, such as osteomyelitis, bacteremia and endocarditis, pneumonia or toxin shock syndrome with a mortality rate up to 40%. S. aureus reveals a high genetic polymorphism and detecting the genotypes is extremely useful to manage and prevent possible outbreaks and to understand the route of infection. One of current and expanded typing method is based on the X region of the spa gene composed of a succession of repeats of 21 to 27 bp. More than 10000 types are known. Extracting the repeats is impossible by hand and needs a dedicated software. Unfortunately the only software on the market is a commercial program from Ridom. This article presents DNAGear, a free and open source software with a user friendly interface written all in Java on top of NetBeans Platform to perform spa typing, detecting new repeats and new spa types and synchronizing automatically the files with the open access database. The installation is easy and the application is platform independent. In fact, the SPA identification is a formal regular expression matching problem and the results are 100% exact. As the program is using Java embedded modules written over string manipulation of well established algorithms, the exactitude of the solution is perfectly established. DNAGear is able to identify the types of the S. aureus sequences and detect both new types and repeats. Comparing to manual processing, which is time consuming and error prone, this application saves a lot of time and effort and gives very reliable results. Additionally, the users do not need to prepare the forward-reverse sequences manually, or even by using additional tools. They can simply create them in DNAGear and perform the typing task. In short, researchers who do not have commercial software will benefit a lot from this application.

Variability of Reviewers' Comments in the Peer Review Process for Orthopaedic Research.

PubMed

Iantorno, Stephanie E; Andras, Lindsay M; Skaggs, David L

2016-07-01

Retrospective analysis of peer review comments. To assess the likelihood that comments provided by peer reviewers of one orthopaedic journal would be similar to comments of reviewers from the same journal and a second journal. The consistency of the peer review process in orthopedic research has not been objectively examined. Nine separate clinical papers related to spinal deformity were submitted for publication in major peer-reviewed journals and initially rejected. The exact same manuscripts were then submitted to different journals. All papers were returned with comments from two to three reviewers from each journal. Reviews were divided into distinct conceptual criticisms that were regarded as separate comments. Comments were compared between reviewers of the same journal and to comments from reviewers of the second journal. When comparing comments from reviewers of the same journal, an average of 11% of comments were repeated (range 0% [0/12] to 23% [3/13]). On average, 20% of comments from the first journal were repeated by a reviewer at the second journal (range 10% [1/10] to 33% [6/18]). If a comment was made by two or more reviewers from the first journal, it had a higher likelihood (43% [6/14]) of being repeated by a reviewer from the second journal. When an identical manuscript is submitted to a second journal after being rejected, 80% of peer review comments from the first journal are not repeated by reviewers from the second journal. One may question if addressing every peer review comment in a rejected manuscript prior to resubmission is an efficient use of resources. Comments that appear twice or more in the first journal review are more likely to reappear and may warrant special attention from the researcher. Level IV. Copyright © 2016 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

Treatment of male urethral strictures - possible reasons for the use of repeated dilatation or internal urethrotomy rather than urethroplasty.

PubMed

Heyns, C F; van der Merwe, J; Basson, J; van der Merwe, A

2012-07-16

To investigate the possible reasons for repeated urethral dilatation or optical internal urethrotomy rather than urethroplasty in the treatment of male urethral strictures. Men referred to the stricture clinic of our institution during the period April 2007 - March 2008 were reviewed and the operative urological procedures performed in the same period were analysed. Statistical analysis was performed using Student's t-test and Fisher's exact test (p<0.05 statistically significant). The mean age of the 125 men was 49.9 years (range 12.8 - 93.4 years). Previous stricture treatment had been given 1 - 2, 3 - 4 and 5 - 6 times in 52%, 32% and 12% of patients, respectively (4% had not undergone treatment). In these groups, previous treatment was dilatation in 70%, 76% and 72%, urethrotomy in 26%, 15% and 28%, and urethroplasty in 4%, 9% and 0, respectively. The group with 5 - 6 compared with 1 - 2 previous treatments was significantly older (mean age 60.2 v. 46.6 years) and had a significantly greater proportion with underlying co-morbidities (80% v. 52%). The group that had undergone urethroplasty compared with 5 - 6 repeated dilatations or urethrotomies was significantly younger (mean age 48.2 v. 60.2 years) with a lower prevalence of co-morbidities (47% v. 80%). During the study period urethroplasty was performed in 16 (2%) of 821 inpatients, whereas 55 men were seen who had undergone ≥3 previous procedures, indicating that urethroplasty was performed in less than one-third of cases in which it would have been the optimal treatment. Owing to limited theatre time, procedures indicated for malignancy, urolithiasis, renal failure and congenital anomalies were performed more often than urethroplasty. Factors that possibly influenced the decision to perform repeated urethrotomy or dilatation instead of urethroplasty were limited theatre time, increased patient age and the presence of underlying co-morbidities.

DNAGear- a free software for spa type identification in Staphylococcus aureus

PubMed Central

2012-01-01

Background Staphylococcus aureus is both human commensal and an important human pathogen, responsible for community-acquired and nosocomial infections ranging from superficial wound infections to invasive infections, such as osteomyelitis, bacteremia and endocarditis, pneumonia or toxin shock syndrome with a mortality rate up to 40%. S. aureus reveals a high genetic polymorphism and detecting the genotypes is extremely useful to manage and prevent possible outbreaks and to understand the route of infection. One of current and expanded typing method is based on the X region of the spa gene composed of a succession of repeats of 21 to 27 bp. More than 10000 types are known. Extracting the repeats is impossible by hand and needs a dedicated software. Unfortunately the only software on the market is a commercial program from Ridom. Findings This article presents DNAGear, a free and open source software with a user friendly interface written all in Java on top of NetBeans Platform to perform spa typing, detecting new repeats and new spa types and synchronizing automatically the files with the open access database. The installation is easy and the application is platform independent. In fact, the SPA identification is a formal regular expression matching problem and the results are 100% exact. As the program is using Java embedded modules written over string manipulation of well established algorithms, the exactitude of the solution is perfectly established. Conclusions DNAGear is able to identify the types of the S. aureus sequences and detect both new types and repeats. Comparing to manual processing, which is time consuming and error prone, this application saves a lot of time and effort and gives very reliable results. Additionally, the users do not need to prepare the forward-reverse sequences manually, or even by using additional tools. They can simply create them in DNAGear and perform the typing task. In short, researchers who do not have commercial software will benefit a lot from this application. PMID:23164452

A Decision Support Framework for Feasibility Analysis of International Space Station (ISS) Research Capability Enhancing Options

NASA Technical Reports Server (NTRS)

Ortiz, James N.; Scott,Kelly; Smith, Harold

2004-01-01

The assembly and operation of the ISS has generated significant challenges that have ultimately impacted resources available to the program's primary mission: research. To address this, program personnel routinely perform trade-off studies on alternative options to enhance research. The approach, content level of analysis and resulting outputs of these studies vary due to many factors, however, complicating the Program Manager's job of selecting the best option. To address this, the program requested a framework be developed to evaluate multiple research-enhancing options in a thorough, disciplined and repeatable manner, and to identify the best option on the basis of cost, benefit and risk. The resulting framework consisted of a systematic methodology and a decision-support toolset. The framework provides quantifiable and repeatable means for ranking research-enhancing options for the complex and multiple-constraint domain of the space research laboratory. This paper describes the development, verification and validation of this framework and provides observations on its operational use.

Corsica: A Multi-Mission Absolute Calibration Site

NASA Astrophysics Data System (ADS)

Bonnefond, P.; Exertier, P.; Laurain, O.; Guinle, T.; Femenias, P.

2013-09-01

In collaboration with the CNES and NASA oceanographic projects (TOPEX/Poseidon and Jason), the OCA (Observatoire de la Côte d'Azur) developed a verification site in Corsica since 1996, operational since 1998. CALibration/VALidation embraces a wide variety of activities, ranging from the interpretation of information from internal-calibration modes of the sensors to validation of the fully corrected estimates of the reflector heights using in situ data. Now, Corsica is, like the Harvest platform (NASA side) [14], an operating calibration site able to support a continuous monitoring with a high level of accuracy: a 'point calibration' which yields instantaneous bias estimates with a 10-day repeatability of 30 mm (standard deviation) and mean errors of 4 mm (standard error). For a 35-day repeatability (ERS, Envisat), due to a smaller time series, the standard error is about the double ( 7 mm).In this paper, we will present updated results of the absolute Sea Surface Height (SSH) biases for TOPEX/Poseidon (T/P), Jason-1, Jason-2, ERS-2 and Envisat.

Analysis of automatic repeat request methods for deep-space downlinks

NASA Technical Reports Server (NTRS)

Pollara, F.; Ekroot, L.

1995-01-01

Automatic repeat request (ARQ) methods cannot increase the capacity of a memoryless channel. However, they can be used to decrease the complexity of the channel-coding system to achieve essentially error-free transmission and to reduce link margins when the channel characteristics are poorly predictable. This article considers ARQ methods on a power-limited channel (e.g., the deep-space channel), where it is important to minimize the total power needed to transmit the data, as opposed to a bandwidth-limited channel (e.g., terrestrial data links), where the spectral efficiency or the total required transmission time is the most relevant performance measure. In the analysis, we compare the performance of three reference concatenated coded systems used in actual deep-space missions to that obtainable by ARQ methods using the same codes, in terms of required power, time to transmit with a given number of retransmissions, and achievable probability of word error. The ultimate limits of ARQ with an arbitrary number of retransmissions are also derived.

Geomagnetic observations on tristan da cunha, south atlantic ocean

USGS Publications Warehouse

Matzka, J.; Olsen, N.; Maule, C.F.; Pedersen, L.W.; Berarducci, A.M.; Macmillan, S.

2009-01-01

Few geomagnetic ground observations exist of the Earth's strongest core field anomaly, the South Atlantic Anomaly (SAA). The geomagnetic repeat station on the island Tristan da Cunha, located half-way between South Africa and South America at 37?? 05' S, 12?? 18' W, is therefore of crucial importance. We have conducted several sets of repeat station measurements during magnetically quiet conditions (Kp 2o or less) in 2004. The procedures are described and the results are compared to those from earlier campaigns and to the predictions of various global field models. Features of the local crustal bias field and the solar quiet daily variation are discussed. We also evaluate the benefit of continuous magnetic field recordings from Tristan da Cunha, and argue that such a data set is a very valuable addition to geomagnetic satellite data. Recently, funds were set up to establish and operate a magnetometer station on Tristan da Cunha during the Swarm magnetic satellite mission (2011-2014).

Comprehensive planning of data archive in Japanese planetary missions

NASA Astrophysics Data System (ADS)

Yamamoto, Yukio; Shinohara, Iku; Hoshino, Hirokazu; Tateno, Naoki; Hareyama, Makoto; Okada, Naoki; Ebisawa, Ken

Comprehensive planning of data archive in Japanese planetary missions Japan Aerospace Exploration Agency (JAXA) provides HAYABUSA and KAGUYA data as planetary data archives. These data archives, however, were prepared independently. Therefore the inconsistency of data format has occurred, and the knowledge of data archiving activity is not inherited. Recently, the discussion of comprehensive planning of data archive has started to prepare up-coming planetary missions, which indicates the comprehensive plan of data archive is required in several steps. The framework of the comprehensive plan is divided into four items: Preparation, Evaluation, Preservation, and Service. 1. PREPARATION FRAMEWORK Data is classified into several types: raw data, level-0, 1, 2 processing data, ancillary data, and etc. The task of mission data preparation is responsible for instrument teams, but preparations beside mission data and support of data management are essential to make unified conventions and formats over instruments in a mission, and over missions. 2. EVALUATION FRAMEWORK There are two meanings of evaluation: format and quality. The format evaluation is often discussed in the preparation framework. The data quality evaluation which is often called quality assurance (QA) or quality control (QC) must be performed by third party apart from preparation teams. An instrument team has the initiative for the preparation itself, and the third-party group is organized to evaluate the instrument team's activity. 3. PRESERVATION FRAMEWORK The main topic of this framework is document management, archiving structure, and simple access method. The mission produces many documents in the process of the development. Instrument de-velopment is no exception. During long-term development of a mission, many documents are obsoleted and updated repeatedly. A smart system will help instrument team to reduce some troubles of document management and archiving task. JAXA attempts to follow PDS manners to do this management since PDS has highly sophisticated archiving structure. In addition, the access method to archived data must be simple and standard well over a decade. 4. SERVICE FRAMEWORK The service framework including planetary data access protocol, PDAP, has been developed to share a stored data effectively. The sophisticated service framework will work not only for publication data, but also for low-level data. JAXA's data query services is under developed based on PDAP, which means that the low-level data can be published in the same manner as level 2 data. In this presentation, we report the detail structure of these four frameworks adopting upcoming Planet-C, Venus Climate Orbiter, mission.

Comparison of CryoSat-2 and ENVISAT radar freeboard over Arctic sea ice: toward an improved Envisat freeboard retrieval

NASA Astrophysics Data System (ADS)

Guerreiro, Kevin; Fleury, Sara; Zakharova, Elena; Kouraev, Alexei; Rémy, Frédérique; Maisongrande, Philippe

2017-09-01

Over the past decade, sea-ice freeboard has been monitored with various satellite altimetric missions with the aim of producing long-term time series of ice thickness. While recent studies have demonstrated the capacity of the CryoSat-2 mission (2010-present) to provide accurate freeboard measurements, the current estimates obtained with the Envisat mission (2002-2012) still require some large improvements. In this study, we first estimate Envisat and CryoSat-2 radar freeboard by using the exact same processing algorithms. We then analyse the freeboard difference between the two estimates over the common winter periods (November 2010-April 2011 and November 2011-March 2012). The analysis of along-track data and gridded radar freeboard in conjunction with Envisat pulse-peakiness (PP) maps suggests that the discrepancy between the two sensors is related to the surface properties of sea-ice floes and to the use of a threshold retracker. Based on the relation between the Envisat pulse peakiness and the radar freeboard difference between Envisat and CryoSat-2, we produce a monthly CryoSat-2-like version of Envisat freeboard. The improved Envisat data set freeboard displays a similar spatial distribution to CryoSat-2 (RMSD = 1.5 cm) during the two ice growth seasons and for all months of the period of study. The comparison of the altimetric data sets with in situ ice draught measurements during the common flight period shows that the improved Envisat data set (RMSE = 12-28 cm) is as accurate as CryoSat-2 (RMSE = 15-21 cm) and much more accurate than the uncorrected Envisat data set (RMSE = 178-179 cm). The comparison of the improved Envisat radar freeboard data set is then extended to the rest of the Envisat mission to demonstrate the validity of PP correction from the calibration period. The good agreement between the improved Envisat data set and the in situ ice draught data set (RMSE = 13-32 cm) demonstrates the potential of the PP correction to produce accurate freeboard estimates over the entire Envisat mission lifetime.

Statistical Prediction of Solar Particle Event Frequency based on the Measurements of Recent Solar Cycles for Acute Radiation Risk Analysis

NASA Astrophysics Data System (ADS)

Kim, M. Y.; Hu, S.; Cucinotta, F. A.

2009-12-01

Large solar particle events (SPEs) present significant acute radiation risks to the crew members during extra-vehicular activities (EVAs) or in lightly shielded space vehicles for space missions beyond the protection of the Earth’s magnetic field. Acute radiation sickness (ARS) can impair performance and result in failure of the mission. Improved forecasting capability and/or early-warning systems and proper shielding solutions are required to stay within NASA’s short-term dose limits. Exactly how to make use of observations of SPEs for predicting occurrence and size is a great challenge, because SPE occurrences themselves are random in nature even though the expected frequency of SPEs is strongly influenced by the time position within the solar activity cycle. Therefore, we developed a probabilistic model approach, where a cumulative expected occurrence curve of SPEs for a typical solar cycle was formed from a non-homogeneous Poisson process model fitted to a database of proton fluence measurements of SPEs that occurred during the past 5 solar cycles (19 -23) and those of large SPEs identified from impulsive nitrate enhancements in polar ice. From the fitted model, the expected frequency of SPEs was estimated at any given proton fluence threshold (ΦE) with energy (E) >30 MeV during a defined space mission period. Corresponding ΦE (E=30, 60, and 100 MeV) fluence distributions were simulated with a random draw from a gamma distribution, and applied for SPE ARS risk analysis for a specific mission period. It has been found that the accurate prediction of deep-seated organ doses was more precisely predicted at high energies, Φ100, than at lower energies such as Φ30 or Φ60, because of the high penetration depth of high energy protons. Estimates of ARS are then described for 90th and 95th percentile events for several mission lengths and for several likely organ dose-rates. The ability to accurately measure high energy protons (50-300 MeV) in real-time is shown to be a crucial issue for crew protection.

European Crew Personal Active Dosimeter (EuCPAD), a novel dosimetry system utilizing operational and scientific synergies for the benefit of humans in space

NASA Astrophysics Data System (ADS)

Straube, Ulrich; Berger, Thomas

A significant expansion of Human presence in space can be recognized over the last decade. Not only the frequency of human space mission did rise, but also time in space, mission duration with extended flights lasting half a year or more are becoming "standard". Despite the challenges to human health and well-being are still significant, or may even increase with mission length and work density. Also radiation exposure in space remains one of the inevitable and dominating factors relevant to crew- health, -safety and therefore mission success. The radiation environment that the space crews are exposed to differs significantly as compared to earth. Exposure in flight exceed doses that are usually received by terrestrial radiation workers on ground. Expanding "medical" demands are not a solely characteristics of current and current and upcoming mission scenarios. Likewise the margins for what is understood as "efficient utilization" for the fully operational science platform ISS, are immense. Understanding, accepting and approaching these challenges ESA-HSO did choose a particular pass of implementation for one of their current developments. Exploiting synergies of research, science and medical operational aspects, the "European Crew Personal Active Dosimeter for Astronauts (EuCPAD)" development exactly addresses these circumstances. It becomes novel part of ESA Radiation Protection Initiative for astronauts. The EuCPAD project aims at the development and manufacturing of an active (powered) dosimeter system to measure astronaut's exposures, support risk assessment dose management by providing a differentiated data set. Final goal is the verification of the system capabilities for medical monitoring at highest standards. The EuCPAD consists of several small portable Personal Active Dosimeters (MU = Mobile Unitas) and a rack mounted docking station “Personal Storage Device (PSD)” for MU storage, data read out and telemetry. The PSD furthermore contains a Tissue Equivalent Proportional Counter (TEPC) and an internal MU(iMU) to enable complex environmental measurements and cross calibrations. This presentation will give an introduction to the dosimetry system and of the current status. The EuCPAD project is carried out under ESA Contract No. 4200023059/09/NL/CP,

The PDS-based Data Processing, Archiving and Management Procedures in Chang'e Mission

NASA Astrophysics Data System (ADS)

Zhang, Z. B.; Li, C.; Zhang, H.; Zhang, P.; Chen, W.

2017-12-01

PDS is adopted as standard format of scientific data and foundation of all data-related procedures in Chang'e mission. Unlike the geographically distributed nature of the planetary data system, all procedures of data processing, archiving, management and distribution are proceeded in the headquarter of Ground Research and Application System of Chang'e mission in a centralized manner. The RAW data acquired by the ground stations is transmitted to and processed by data preprocessing subsystem (DPS) for the production of PDS-compliant Level 0 Level 2 data products using established algorithms, with each product file being well described using an attached label, then all products with the same orbit number are put together into a scheduled task for archiving along with a XML archive list file recoding all product files' properties such as file name, file size etc. After receiving the archive request from DPS, data management subsystem (DMS) is provoked to parse the XML list file to validate all the claimed files and their compliance to PDS using a prebuilt data dictionary, then to exact metadata of each data product file from its PDS label and the fields of its normalized filename. Various requirements of data management, retrieving, distribution and application can be well met using the flexible combination of the rich metadata empowered by the PDS. In the forthcoming CE-5 mission, all the design of data structure and procedures will be updated from PDS version 3 used in previous CE-1, CE-2 and CE-3 missions to the new version 4, the main changes would be: 1) a dedicated detached XML label will be used to describe the corresponding scientific data acquired by the 4 instruments carried, the XML parsing framework used in archive list validation will be reused for the label after some necessary adjustments; 2) all the image data acquired by the panorama camera, landing camera and lunar mineralogical spectrometer should use an Array_2D_Image/Array_3D_Image object to store image data, and use a Table_Character object to store image frame header; the tabulated data acquired by the lunar regolith penetrating radar should use a Table_Binary object to store measurements.

Statistical Prediction of Solar Particle Event Frequency Based on the Measurements of Recent Solar Cycles for Acute Radiation Risk Analysis

NASA Technical Reports Server (NTRS)

Myung-Hee, Y. Kim; Shaowen, Hu; Cucinotta, Francis A.

2009-01-01

Large solar particle events (SPEs) present significant acute radiation risks to the crew members during extra-vehicular activities (EVAs) or in lightly shielded space vehicles for space missions beyond the protection of the Earth's magnetic field. Acute radiation sickness (ARS) can impair performance and result in failure of the mission. Improved forecasting capability and/or early-warning systems and proper shielding solutions are required to stay within NASA's short-term dose limits. Exactly how to make use of observations of SPEs for predicting occurrence and size is a great challenge, because SPE occurrences themselves are random in nature even though the expected frequency of SPEs is strongly influenced by the time position within the solar activity cycle. Therefore, we developed a probabilistic model approach, where a cumulative expected occurrence curve of SPEs for a typical solar cycle was formed from a non-homogeneous Poisson process model fitted to a database of proton fluence measurements of SPEs that occurred during the past 5 solar cycles (19 - 23) and those of large SPEs identified from impulsive nitrate enhancements in polar ice. From the fitted model, the expected frequency of SPEs was estimated at any given proton fluence threshold (Phi(sub E)) with energy (E) >30 MeV during a defined space mission period. Corresponding Phi(sub E) (E=30, 60, and 100 MeV) fluence distributions were simulated with a random draw from a gamma distribution, and applied for SPE ARS risk analysis for a specific mission period. It has been found that the accurate prediction of deep-seated organ doses was more precisely predicted at high energies, Phi(sub 100), than at lower energies such as Phi(sub 30) or Phi(sub 60), because of the high penetration depth of high energy protons. Estimates of ARS are then described for 90th and 95th percentile events for several mission lengths and for several likely organ dose-rates. The ability to accurately measure high energy protons (50-300 MeV) in real-time is shown to be a crucial issue for crew protection.

Testing Starshade Manufacturing and Deployment Through NASA's Technology Development for Exoplanet Missions Program

NASA Astrophysics Data System (ADS)

Kasdin, N. J.; Shaklan, S.; Lisman, D.; Thomson, M.; Cady, E.; Lo, A.; Macintosh, B.

2014-01-01

An external occulter is a satellite employing a large screen, or starshade, that flies in formation with a spaceborne telescope to provide the starlight suppression needed for detecting and characterizing exoplanets. Among the advantages of using an occulter are the broadband allowed for characterization and the removal of light before entering the observatory, greatly relaxing the requirements on the telescope and instrument. In this poster we report on the results of our two Technology Development for Exoplanet Missions (TDEM) studies. In the first we examined the manufacturability and metrology of starshade petals, successfully constructing a full size petal from flight like materials and showing through precise edge shape measurements that an occulter made with petals consistent with the measured accuracy would achieve close to 10^-10 contrast. Our second TDEM tested the deployment precision of a roughly half-scale starshade. We demonstrated the deployment of an existing deployable truss outfitted with four sub-scale petals and a custom designed central hub. We showed that the system can be deployed multiple times with a repeatable positioning accuracy of the petals better than the requirement of 1.0 mm. The combined results of these two TDEM projects has significantly advanced the readiness level of occulter technology and moved the community closer to a realizable mission.

Global Precipitation Measurement (GPM) Orbit Design and Autonomous Maneuvers

NASA Technical Reports Server (NTRS)

Folta, David; Mendelsohn, Chad; Mailhe, Laurie

2003-01-01

The NASA Goddard Space Flight Center's Global Precipitation Measurement (GPM) mission must meet the challenge of measuring worldwide precipitation every three hours. The GPM core spacecraft, part of a constellation, will be required to maintain a circular orbit in a high drag environment at a near-critical inclination. Analysis shows that a mean orbit altitude of 407 km is necessary to prevent ground track repeating. Combined with goals to minimize maneuver operation impacts to science data collection and to enable reasonable long-term orbit predictions, the GPM project has decided to fly the GSFC autonomous maneuver system, AutoCon(TM). This system is a follow-up version of the highly successful New Millennium Program technology flown onboard the Earth Observing-1 formation flying mission. This paper presents the driving science requirements and goals of the GPM mission and shows how they will be met. Selection of the mean semi-major axis, eccentricity, and the AV budget for several ballistic properties are presented. The architecture of the autonomous maneuvering system to meet the goals and requirements is presented along with simulations using GPM parameters. Additionally, the use of the GPM autonomous system to mitigate possible collision avoidance and to aid other spacecraft systems during navigation outages is explored.

General relativistic satellite astrometry. II. Modeling parallax and proper motion

NASA Astrophysics Data System (ADS)

de Felice, F.; Bucciarelli, B.; Lattanzi, M. G.; Vecchiato, A.

2001-07-01

The non-perturbative general relativistic approach to global astrometry introduced by de Felice et al. (\\cite{defetal}) is here extended to account for the star motions on the Schwarzschild celestial sphere. A new expression of the observables, i.e. angular distances among stars, is provided, which takes into account the effects of parallax and proper motions. This dynamical model is then tested on an end-to-end simulation of the global astrometry mission GAIA. The results confirm the findings of our earlier work, which applied to the case of a static (angular coordinates only) sphere. In particular, measurements of large arcs among stars (each measurement good to ~ 100 mu arcsec, as expected for V ~ 17 mag stars) repeated over an observing period comparable to the mission lifetime foreseen for GAIA, can be modeled to yield estimates of positions, parallaxes, and annual proper motions good to ~ 15 mu arcsec. This second round of experiments confirms, within the limitations of the simulation and the assumptions of the current relativistic model, that the space-born global astrometry initiated with Hipparcos can be pushed down to the 10-5 arcsec accuracy level proposed with the GAIA mission. Finally, the simplified case we have solved can be used as reference for testing the limiting behavior of more realistic models as they become available.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, a quality technician checks the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, quality technicians check the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, quality technicians check components of the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, quality technicians check the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environment Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, a quality technician checks the control panel on hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

The Kepler End-to-End Data Pipeline: From Photons to Far Away Worlds

NASA Technical Reports Server (NTRS)

Cooke, Brian; Thompson, Richard; Standley, Shaun

2012-01-01

Launched by NASA on 6 March 2009, the Kepler Mission has been observing more than 100,000 targets in a single patch of sky between the constellations Cygnus and Lyra almost continuously for the last two years looking for planetary systems using the transit method. As of October 2011, the Kepler spacecraft has collected and returned to Earth just over 290 GB of data, identifying 1235 planet candidates with 25 of these candidates confirmed as planets via ground observation. Extracting the telltale signature of a planetary system from stellar photometry where valid signal transients can be small as a 40 ppm is a difficult and exacting task. The end-to end processing of determining planetary candidates from noisy, raw photometric measurements is discussed.

Mount Pinatubo, Philippines

NASA Image and Video Library

1994-09-30

STS068-232-083 (30 September-11 October 1994) --- This is a view of Mount Pinatubo, Philippine Islands, orient with the coast to the top. View westward across central Luzon and Mount Pinatubo. Manilla Bay is in partial sunglint along the left edge of the frame. The extensive flows of volcanic ash (lahars) extending from the mountain are readily seen despite partial cloud cover. The ash is mobilized with every rain in this typhoon-ridden region, flowing down valleys, filling drainage channels, and covering fields and towns. The STS-68 crew obtained excellent photographs of the region, for comparison to the radar data also obtained on the mission. Photographs in sunglint have proven particularly helpful because they show the exact outlines of surface water, which provides a datum point for the radar returns.

The Ocean Surface Topography Mission (OSTM)

NASA Astrophysics Data System (ADS)

Neeck, Steven P.; Vaze, Parag V.

2008-10-01

The Ocean Surface Topography Mission (OSTM), also known as Jason-2, will extend into the next decade the continuous climate data record of sea surface height measurements begun in 1992 by the joint NASA/Centre National d'Etudes Spatiales (CNES) TOPEX/Poseidon mission and continued by the NASA/CNES Jason-1 mission in 2001. This multi-decadal record has already helped scientists study the issue of global sea level rise and better understand how ocean circulation and climate change are related. With OSTM, high-precision ocean altimetry has come of age. The mission will serve as a bridge to transition the collection of these measurements to the world's weather and climate forecasting agencies. The agencies will use them for short- and seasonal-to-long-range weather and climate forecasting. OSTM is designed to last at least three years. It will be placed in the same orbit (1,336 kilometers) as Jason-1 and will move along the same ground track at an inclination of 66 degrees to the equator. It will repeat its ground track every 10 days, covering 95 percent of the world's ice-free oceans. A tandem mission between Jason-1 and OSTM will be conducted to further improve tide models in coastal and shallow seas, and to better understand the dynamics of ocean currents and eddies. OSTM is an international and interagency mission developed and operated as a four-party collaboration among NASA, the National Oceanic and Atmospheric Administration (NOAA), CNES, and the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT). CNES is providing the spacecraft, NASA and CNES are jointly providing the payload instruments and NASA is providing the launch vehicle. After completing the onorbit commissioning of the spacecraft, CNES will hand over operation and control of the spacecraft to NOAA. NOAA and EUMETSAT will generate the near-real-time products and distribute them to users. OSTM was launched from Vandenberg Air Force Base, California on June 20, 2008. Launch and Early Orbit Operations (LEOP) and the on-orbit Assessment Phase have been completed. Preliminary science data show excellent performance.

AVIATR—Aerial Vehicle for In-situ and Airborne Titan Reconnaissance. A Titan airplane mission concept

NASA Astrophysics Data System (ADS)

Barnes, Jason W.; Lemke, Lawrence; Foch, Rick; McKay, Christopher P.; Beyer, Ross A.; Radebaugh, Jani; Atkinson, David H.; Lorenz, Ralph D.; Le Mouélic, Stéphane; Rodriguez, Sebastien; Gundlach, Jay; Giannini, Francesco; Bain, Sean; Flasar, F. Michael; Hurford, Terry; Anderson, Carrie M.; Merrison, Jon; Ádámkovics, Máté; Kattenhorn, Simon A.; Mitchell, Jonathan; Burr, Devon M.; Colaprete, Anthony; Schaller, Emily; Friedson, A. James; Edgett, Kenneth S.; Coradini, Angioletta; Adriani, Alberto; Sayanagi, Kunio M.; Malaska, Michael J.; Morabito, David; Reh, Kim

2012-03-01

We describe a mission concept for a stand-alone Titan airplane mission: Aerial Vehicle for In-situ and Airborne Titan Reconnaissance (AVIATR). With independent delivery and direct-to-Earth communications, AVIATR could contribute to Titan science either alone or as part of a sustained Titan Exploration Program. As a focused mission, AVIATR as we have envisioned it would concentrate on the science that an airplane can do best: exploration of Titan's global diversity. We focus on surface geology/hydrology and lower-atmospheric structure and dynamics. With a carefully chosen set of seven instruments—2 near-IR cameras, 1 near-IR spectrometer, a RADAR altimeter, an atmospheric structure suite, a haze sensor, and a raindrop detector—AVIATR could accomplish a significant subset of the scientific objectives of the aerial element of flagship studies. The AVIATR spacecraft stack is composed of a Space Vehicle (SV) for cruise, an Entry Vehicle (EV) for entry and descent, and the Air Vehicle (AV) to fly in Titan's atmosphere. Using an Earth-Jupiter gravity assist trajectory delivers the spacecraft to Titan in 7.5 years, after which the AVIATR AV would operate for a 1-Earth-year nominal mission. We propose a novel `gravity battery' climb-then-glide strategy to store energy for optimal use during telecommunications sessions. We would optimize our science by using the flexibility of the airplane platform, generating context data and stereo pairs by flying and banking the AV instead of using gimbaled cameras. AVIATR would climb up to 14 km altitude and descend down to 3.5 km altitude once per Earth day, allowing for repeated atmospheric structure and wind measurements all over the globe. An initial Team-X run at JPL priced the AVIATR mission at FY10 715M based on the rules stipulated in the recent Discovery announcement of opportunity. Hence we find that a standalone Titan airplane mission can achieve important science building on Cassini's discoveries and can likely do so within a New Frontiers budget.

A New Approach to Micro-arcsecond Astrometry with SIM Allowing Early Mission Narrow Angle Measurements of Compelling Astronomical Targets

NASA Technical Reports Server (NTRS)

Shaklan, Stuart; Pan, Xiaopei

2004-01-01

The Space Interferometry Mission (SIM) is capable of detecting and measuring the mass of terrestrial planets around stars other than our own. It can measure the mass of black holes and the visual orbits of radio and x-ray binary sources. SIM makes possible a new level of understanding of complex astrophysical processes. SIM achieves its high precision in the so-called narrow-angle regime. This is defined by a 1 degree diameter field in which the position of a target star is measured with respect to a set of reference stars. The observation is performed in two parts: first, SIM observes a grid of stars that spans the full sky. After a few years, repeated observations of the grid allow one to determine the orientation of the interferometer baseline. Second, throughout the mission, SIM periodically observes in the narrow-angle mode. Every narrow-angle observation is linked to the grid to determine the precise attitude and length of the baseline. The narrow angle process demands patience. It is not until five years after launch that SIM achieves its ultimate accuracy of 1 microarcsecond. The accuracy is degraded by a factor of approx. 2 at mid-mission. Our work proposes a technique for narrow angle astrometry that does not rely on the measurement of grid stars. This technique, called Gridless Narrow Angle Astrometry (GNAA) can obtain microarcsecond accuracy and can detect extra-solar planets and other exciting objects with a few days of observation. It can be applied as early as during the first six months of in-orbit calibration (IOC). The motivations for doing this are strong. First, and obviously, it is an insurance policy against a catastrophic mid-mission failure. Second, at the start of the mission, with several space-based interferometers in the planning or implementation phase, NASA will be eager to capture the public's imagination with interferometric science. Third, early results and a technique that can duplicate those results throughout the mission will give the analysts important experience in the proper use and calibration of SIM.

AVIATR - Aerial Vehicle for In-situ and Airborne Titan Reconnaissance A Titan Airplane Mission Concept

NASA Technical Reports Server (NTRS)

Barnes, Jason W.; Lemke, Lawrence; Foch, Rick; McKay, Christopher P.; Beyer, Ross A.; Radebaugh, Jani; Atkinson, David H.; Lorenz, Ralph D.; LeMouelic, Stephane; Rodriguez, Sebastien;

Monitoring of Crew Activity with FAMOS

NASA Astrophysics Data System (ADS)

Wolf, L.; Cajochen, C.; Bromundt, V.

2007-10-01

The success of long duration space missions, such as manned missions to Mars, depends on high and sustained levels of vigilance and performance of astronauts and operators working in the technology rich environment of a spacecraft. Experiment 'Monitoring of Crew Activity with FAMOS' was set up to obtain operational experience with complimentary methods / technologies to assess the alertness / sleepiness status of selected AustroMars crewmembers on a daily basis. We applied a neurobehavioral test battery consisting of 1) Karolinska Sleepiness Scale KSS, 2) Karolinska Drowsiness Test KDT, 3) Psychomotor Vigilance Task PVT, combined with 4) left eye video recordings with an early prototype of the FAMOS Fatigue Monitoring System headset currently being developed by Sowoon Technologies (CH), and 5) Actiwatches that were worn continuously. A test battery required approximately 15 minutes and was repeated up to 4 times daily by 2 to 4 subjects. Here we present the data analysis of methods 1, 2, 3, and 5, while data analysis of method 4 is still in progress.

Mean hydrography on the continental shelf from 26 repeat glider deployments along Southeastern Australia

NASA Astrophysics Data System (ADS)

Schaeffer, Amandine; Roughan, Moninya; Austin, Tim; Everett, Jason D.; Griffin, David; Hollings, Ben; King, Edward; Mantovanelli, Alessandra; Milburn, Stuart; Pasquer, Benedicte; Pattiaratchi, Charitha; Robertson, Robin; Stanley, Dennis; Suthers, Iain; White, Dana

2016-08-01

Since 2008, 26 glider missions have been undertaken along the continental shelf of southeastern Australia. Typically these missions have spanned the continental shelf on the inshore edge of the East Australian Current from 29.5-33.5°S. This comprehensive dataset of over 33,600 CTD profiles from the surface to within 10 m of the bottom in water depths ranging 25-200 m provides new and unprecedented high resolution observations of the properties of the continental shelf waters adjacent to a western boundary current, straddling the region where it separates from the coast. The region is both physically and biologically significant, and is also in a hotspot of ocean warming. We present gridded mean fields for temperature, salinity and density, but also dissolved oxygen and chlorophyll-a fluorescence indicative of phytoplankton biomass. This data will be invaluable for understanding shelf stratification, circulation, biophysical and bio-geochemical interactions, as well as for the validation of high-resolution ocean models or serving as teaching material.

FIRST LIGHT: MeV ASTROPHYSICS FROM THE MOON

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Richard S.; Lawrence, David J., E-mail: richard.s.miller@uah.edu

We report evidence of the first astrophysical source detected from the Moon at MeV energies. Our detection of Cygnus X-1 is a validation of a new investigative paradigm in which the lunar environment is intrinsic to the detection approach: the Lunar Occultation Technique (LOT). NASA’s Lunar Prospector mission served as a proxy for a dedicated LOT-based mission. The characteristic signature of temporal modulation, generated by repeated lunar occultations and encoded within acquired gamma-ray data (0.5–9 MeV), is consistent with an unambiguous detection of Cygnus X-1 at 5.4 σ significance. Source localization and long-term monitoring capabilities of the LOT are alsomore » demonstrated. This “first light” detection verifies the basic tenets of the LOT methodology, reinforces its feasibility as an alternative astronomical detection paradigm for nuclear astrophysics investigations, and is an illustration of the fundamental benefits of the Moon as a platform for science.« less

Color View 'Dodo' and 'Baby Bear' Trenches

NASA Technical Reports Server (NTRS)

2008-01-01

NASA's Phoenix Mars Lander's Surface Stereo Imager took this image on Sol 14 (June 8, 2008), the 14th Martian day after landing. It shows two trenches dug by Phoenix's Robotic Arm.

Soil from the right trench, informally called 'Baby Bear,' was delivered to Phoenix's Thermal and Evolved-Gas Analyzer, or TEGA, on Sol 12 (June 6). The following several sols included repeated attempts to shake the screen over TEGA's oven number 4 to get fine soil particles through the screen and into the oven for analysis.

The trench on the left is informally called 'Dodo' and was dug as a test.

Each of the trenches is about 9 centimeters (3 inches) wide. This view is presented in approximately true color by combining separate exposures taken through different filters of the Surface Stereo Imager.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

Mean hydrography on the continental shelf from 26 repeat glider deployments along Southeastern Australia.

PubMed

Schaeffer, Amandine; Roughan, Moninya; Austin, Tim; Everett, Jason D; Griffin, David; Hollings, Ben; King, Edward; Mantovanelli, Alessandra; Milburn, Stuart; Pasquer, Benedicte; Pattiaratchi, Charitha; Robertson, Robin; Stanley, Dennis; Suthers, Iain; White, Dana

2016-08-30

Since 2008, 26 glider missions have been undertaken along the continental shelf of southeastern Australia. Typically these missions have spanned the continental shelf on the inshore edge of the East Australian Current from 29.5-33.5°S. This comprehensive dataset of over 33,600 CTD profiles from the surface to within 10 m of the bottom in water depths ranging 25-200 m provides new and unprecedented high resolution observations of the properties of the continental shelf waters adjacent to a western boundary current, straddling the region where it separates from the coast. The region is both physically and biologically significant, and is also in a hotspot of ocean warming. We present gridded mean fields for temperature, salinity and density, but also dissolved oxygen and chlorophyll-a fluorescence indicative of phytoplankton biomass. This data will be invaluable for understanding shelf stratification, circulation, biophysical and bio-geochemical interactions, as well as for the validation of high-resolution ocean models or serving as teaching material.

Observations of Turbulence in a Kelvin-Helmholtz Event on 8 September 2015 by the Magnetospheric Multiscale Mission

NASA Technical Reports Server (NTRS)

Stawarz, J. E.; Eriksson, S.; Wilder, F. D.; Ergun, R. E.; Schwartz, S. J.; Pouquet, A.; Burch, J. L.; Giles, B. L.; Khotyaintsev, Y.; Le Contel, O.;

Person-to-person transfer of Candida albicans in the spacecraft environment

NASA Technical Reports Server (NTRS)

Pierson, D. L.; Mehta, S. K.; Magee, B. B.; Mishra, S. K.

1995-01-01

We assessed the exchange of Candida albicans among crew members during 10 Space Shuttle missions. Throat, nasal, urine and faecal specimens were collected from 61 crew members twice before and once after space flights ranging from 7 to 10 days in duration; crews consisted of groups of five, six or seven men and women. Candida albicans was isolated at least once from 20 of the 61 subjects (33%). Candida strains were identified by restriction-fragment length polymorphism (RFLP) after digestion by the endonucleases EcoRI and HinfI; further discrimination was gained by Southern blot hybridization with the C. albicans repeat fragment 27A. Eighteen of the 20 Candida-positive crew members carried different strains of C. albicans in the specimens collected. Possible transfer of C. albicans between members of the same crew was demonstrated only once in the 10 missions studied. We conclude that the transfer of C. albicans among crew members during Space Shuttle flights is less frequent than had been predicted from earlier reports.

Empire's recent history, as seen from the Special Advisory Review Panel on Blue Cross.

PubMed

Barba, J J

1997-01-01

Empire is a smaller and more financially stable company that no longer has an externally imposed social mission. The board and management of Empire have decided to convert to a for-profit company, to compete in the marketplace. In light of this decision, they also decided to turn over the company's charitable value to a new foundation. Because Empire's board has chosen not to maintain a social mission, the Panel strongly supports its proposal to turn over the full value of the charitable asset. This will allow the asset to be used for purposes that are in keeping with Empire's original social mission. Exactly how this asset should be valued, what form it should take, when it should be turned over, who should control the assets, and what activities it should support are just a few of the many important issues that must be resolved during the next few months. Empire will not and should not remain stagnant during the next few months. Given the rapidly evolving health-care market, Empire's board and management must continue to pursue a market strategy that strengthens the company. However, given the factors discussed earlier--hospital deregulation, the increasingly competitive managed-care market, and other pressures in the health-care environment--it is clear that the road ahead for Empire will not be a smooth one and that the company's financial resurgence is no guarantee of continued stability. Much hard work remains. I am confident that Empire's board and its management will continue to do its part, that the Panel will continue to do likewise.

Empire's recent history, as seen from the Special Advisory Review Panel on Blue Cross.

PubMed Central

Barba, J. J.

1997-01-01

Empire is a smaller and more financially stable company that no longer has an externally imposed social mission. The board and management of Empire have decided to convert to a for-profit company, to compete in the marketplace. In light of this decision, they also decided to turn over the company's charitable value to a new foundation. Because Empire's board has chosen not to maintain a social mission, the Panel strongly supports its proposal to turn over the full value of the charitable asset. This will allow the asset to be used for purposes that are in keeping with Empire's original social mission. Exactly how this asset should be valued, what form it should take, when it should be turned over, who should control the assets, and what activities it should support are just a few of the many important issues that must be resolved during the next few months. Empire will not and should not remain stagnant during the next few months. Given the rapidly evolving health-care market, Empire's board and management must continue to pursue a market strategy that strengthens the company. However, given the factors discussed earlier--hospital deregulation, the increasingly competitive managed-care market, and other pressures in the health-care environment--it is clear that the road ahead for Empire will not be a smooth one and that the company's financial resurgence is no guarantee of continued stability. Much hard work remains. I am confident that Empire's board and its management will continue to do its part, that the Panel will continue to do likewise. PMID:9439862

Three-Dimensional Analysis of Deep Space Network Antenna Coverage

NASA Technical Reports Server (NTRS)

Kegege, Obadiah; Fuentes, Michael; Meyer, Nicholas; Sil, Amy

2012-01-01

There is a need to understand NASA s Deep Space Network (DSN) coverage gaps and any limitations to provide redundant communication coverage for future deep space missions, especially for manned missions to Moon and Mars. The DSN antennas are required to provide continuous communication coverage for deep space flights, interplanetary missions, and deep space scientific observations. The DSN consists of ground antennas located at three sites: Goldstone in USA, Canberra in Australia, and Madrid in Spain. These locations are not separated by the exactly 120 degrees and some DSN antennas are located in the bowl-shaped mountainous terrain to shield against radiofrequency interference resulting in a coverage gap in the southern hemisphere for the current DSN architecture. To analyze the extent of this gap and other coverage limitations, simulations of the DSN architecture were performed. In addition to the physical properties of the DSN assets, the simulation incorporated communication forward link calculations and azimuth/elevation masks that constrain the effects of terrain for each DSN antenna. Analysis of the simulation data was performed to create coverage profiles with the receiver settings at a deep space altitudes ranging from 2 million to 10 million km and a spherical grid resolution of 0.25 degrees with respect to longitude and latitude. With the results of these simulations, two- and three-dimensional representations of the area without communication coverage and area with coverage were developed, showing the size and shape of the communication coverage gap projected in space. Also, the significance of this communication coverage gap is analyzed from the simulation data.

Rock Moved by Mars Lander Arm

NASA Technical Reports Server (NTRS)

2008-01-01

The robotic arm on NASA's Phoenix Mars Lander slid a rock out of the way during the mission's 117th Martian day (Sept. 22, 2008) to gain access to soil that had been underneath the rock.The lander's Surface Stereo Imager took the two images for this stereo view later the same day, showing the rock, called 'Headless,' after the arm pushed it about 40 centimeters (16 inches) from its previous location.

'The rock ended up exactly where we intended it to,' said Matt Robinson of NASA's Jet Propulsion Laboratory, robotic arm flight software lead for the Phoenix team.

The arm had enlarged the trench near Headless two days earlier in preparation for sliding the rock into the trench. The trench was dug to about 3 centimeters (1.2 inches) deep. The ground surface between the rock's prior position and the lip of the trench had a slope of about 3 degrees downward toward the trench. Headless is about the size and shape of a VHS videotape.

The Phoenix science team sought to move the rock in order to study the soil and the depth to subsurface ice underneath where the rock had been.

This image was taken at about 12:30 p.m., local solar time on Mars. The view is to the north northeast of the lander.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by JPL, Pasadena, Calif. Spacecraft development was by Lockheed Martin Space Systems, Denver.

Scheduling Capacitated One-Way Vehicles on Paths with Deadlines

NASA Astrophysics Data System (ADS)

Uchida, Jun; Karuno, Yoshiyuki; Nagamochi, Hiroshi

In this paper, we deal with a scheduling problem of minimizing the number of employed vehicles on paths. Let G=(V,E) be a path with a set V={vi|i=1,2,...,n} of vertices and a set E={{vi,vi+1}|i=1,2,...,n-1} of edges. Vehicles with capacity b are initially situated at v1. There is a job i at each vertex vi∈V, which has its own handling time hi and deadline di. With each edge {vi,vi+1}∈E, a travel time wi,i+1 is associated. Each job is processed by exactly one vehicle, and the number of jobs processed by a vehicle does not exceed the capacity b. A routing of a vehicle is called one-way if the vehicle visits every edge {vi,vi+1} exactly once (i.e., it simply moves from v1 to vn on G). Any vehicle is assumed to follow the one-way routing constraint. The problem asks to find a schedule that minimizes the number of one-way vehicles, meeting the deadline and capacity constraints. A greedy heuristic is proposed, which repeats a dynamic programming procedure for a single one-way vehicle problem of maximizing the number of non-tardy jobs. We show that the greedy heuristic runs in O(n3) time, and the approximation ratio is at most ln b+1.

Pronunciation difficulty, temporal regularity, and the speech-to-song illusion.

PubMed

Margulis, Elizabeth H; Simchy-Gross, Rhimmon; Black, Justin L

2015-01-01

The speech-to-song illusion (Deutsch et al., 2011) tracks the perceptual transformation from speech to song across repetitions of a brief spoken utterance. Because it involves no change in the stimulus itself, but a dramatic change in its perceived affiliation to speech or to music, it presents a unique opportunity to comparatively investigate the processing of language and music. In this study, native English-speaking participants were presented with brief spoken utterances that were subsequently repeated ten times. The utterances were drawn either from languages that are relatively difficult for a native English speaker to pronounce, or languages that are relatively easy for a native English speaker to pronounce. Moreover, the repetition could occur at regular or irregular temporal intervals. Participants rated the utterances before and after the repetitions on a 5-point Likert-like scale ranging from "sounds exactly like speech" to "sounds exactly like singing." The difference in ratings before and after was taken as a measure of the strength of the speech-to-song illusion in each case. The speech-to-song illusion occurred regardless of whether the repetitions were spaced at regular temporal intervals or not; however, it occurred more readily if the utterance was spoken in a language difficult for a native English speaker to pronounce. Speech circuitry seemed more liable to capture native and easy-to-pronounce languages, and more reluctant to relinquish them to perceived song across repetitions.

Substructure of a Tunisian Berber population as inferred from 15 autosomal short tandem repeat loci.

PubMed

Khodjet-El-Khil, Houssein; Fadhlaoui-Zid, Karima; Gusmão, Leonor; Alves, Cíntia; Benammar-Elgaaied, Amel; Amorim, Antonio

2008-08-01

Currently, language and cultural practices are the only criteria to distinguish between Berber autochthonous Tunisian populations. To evaluate these populations' possible genetic structure and differentiation, we have analyzed 15 autosomal short tandem repeat loci (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, TPOX, VWA, D2S1338, and D19S433) in three southern Tunisian Berber groups: Sened, Matmata, and Chenini-Douiret. The exact test of population differentiation based on allele frequencies at the 15 loci shows significant P values at 7 loci between Chenini-Douiret and both Sened and Matmata, whereas just 5 loci show significant P values between Sened and Matmata. Comparative analyses between the three Berber groups based on genetic distances show that P values for F(ST) distances are significant between the three Berber groups. Population analysis performed using Structure shows a clear differentiation between these Berber groups, with strong genetic isolation of Chenini-Douiret. These results confirm at the autosomal level the high degree of heterogeneity of Tunisian Berber populations that had been previously reported for uniparental markers.

Effects of a Brief Empowerment Program for Families of Persons with Mental Illness in South Korea: A Pilot Study.

PubMed

Hyun, Myung-Sun; Nam, Kyoung A; Kim, Hyunlye

2018-05-30

Families of persons with mental illness (PMIs) are considered important resources for PMIs rather than as contributors to their mental illness. However, these families experience not only the burden of caregiving but also social stigma and discrimination in various aspects of their lives, and their psychosocial needs tend to be overlooked. This was a pilot study to explore the effects of a brief empowerment program on the empowerment and quality of life of families of PMIs in South Korea. A repeated-measures design with a control group and pre/post-follow-up testing was used. We enrolled 18 participants (experimental group = 9, control group = 9). The experimental group participated in an empowerment program consisting of four sessions over 4 weeks. Data were collected before and after the program, and again 4 weeks later. The χ 2 -test, Fisher's exact probability test, t-test, and repeated-measures analysis of covariance were used, as appropriate, to analyze data. The program significantly increased empowerment (F = 4.66, p = .020) and quality of life (F = 5.83, p = .009) among participants in the experimental group over time. Its therapeutic features, such as sharing their experiences, discussion, and presentations, can be applied to create effective psychosocial interventions for families of PMIs.

An R2 statistic for fixed effects in the linear mixed model.

PubMed

Edwards, Lloyd J; Muller, Keith E; Wolfinger, Russell D; Qaqish, Bahjat F; Schabenberger, Oliver

2008-12-20

Statisticians most often use the linear mixed model to analyze Gaussian longitudinal data. The value and familiarity of the R(2) statistic in the linear univariate model naturally creates great interest in extending it to the linear mixed model. We define and describe how to compute a model R(2) statistic for the linear mixed model by using only a single model. The proposed R(2) statistic measures multivariate association between the repeated outcomes and the fixed effects in the linear mixed model. The R(2) statistic arises as a 1-1 function of an appropriate F statistic for testing all fixed effects (except typically the intercept) in a full model. The statistic compares the full model with a null model with all fixed effects deleted (except typically the intercept) while retaining exactly the same covariance structure. Furthermore, the R(2) statistic leads immediately to a natural definition of a partial R(2) statistic. A mixed model in which ethnicity gives a very small p-value as a longitudinal predictor of blood pressure (BP) compellingly illustrates the value of the statistic. In sharp contrast to the extreme p-value, a very small R(2) , a measure of statistical and scientific importance, indicates that ethnicity has an almost negligible association with the repeated BP outcomes for the study.

Evaluation of cognitive characteristics of patients developing manifestations of parkinsonism secondary to long-term ephedrone use.

PubMed

Koksal, Ayhan; Keskinkılıc, Cahit; Sozmen, Mehmet Vedat; Dirican, Ayten Ceyhan; Aysal, Fikret; Altunkaynak, Yavuz; Baybas, Sevim

2014-01-01

In this study, cognitive functions of 9 patients developing parkinsonism due to chronic manganese intoxication by intravenous methcathinone solution were investigated using detailed neuropsychometric tests. Attention deficit, verbal and nonverbal memory, visuospatial function, constructive ability, language, and executive (frontal) functions of 9 patients who were admitted to our clinic with manifestations of chronic manganese intoxication and 9 control subjects were assessed using neuropsychometric tests. Two years later, detailed repeat neuropsychometric tests were performed in the patient group. The results were evaluated using the χ(2) test, Fisher's exact probability test, Student's t test and the Mann-Whitney U test. While there was no statistically significant difference between the two groups in language functions, visuospatial functions and constructive ability, a statistically significant difference was noted between both groups regarding attention (p = 0.032), calculation (p = 0.004), recall and recognition domains of verbal memory, nonverbal memory (p = 0.021) and some domains of frontal functions (Stroop-5 and spontaneous recovery) (p = 0.022 and 0.012). Repeat neuropsychometric test results of the patients were not statistically significant 2 years later. It has been observed that cognitive dysfunction seen in parkinsonism secondary to chronic manganese intoxication may be long-lasting and may not recover as observed in motor dysfunction. © 2014 S. Karger AG, Basel.

DNA-based differentiation of the Ecuadorian cocoa types CCN-51 and Arriba based on sequence differences in the chloroplast genome.

PubMed

Herrmann, Luise; Haase, Ilka; Blauhut, Maike; Barz, Nadine; Fischer, Markus

2014-12-17

Two cocoa types, Arriba and CCN-51, are being cultivated in Ecuador. With regard to the unique aroma, Arriba is considered a fine cocoa type, while CCN-51 is a bulk cocoa because of its weaker aroma. Because it is being assumed that Arriba is mixed with CCN-51, there is an interest in the analytical differentiation of the two types. Two methods to identify CCN-51 adulterations in Arriba cocoa were developed on the basis of differences in the chloroplast DNA. On the one hand, a different repeat of the sequence TAAAG in the inverted repeat region results in a different length of amplicons for the two cocoa types, which can be detected by agarose gel electrophoresis, capillary gel electrophoresis, and denaturing high-performance liquid chromatography. On the other hand, single nucleotide polymorphisms (SNPs) between the CCN-51 and Arriba sequences represent restriction sites, which can be used for restriction fragment length polymorphism analysis. A semi-quantitative analysis based on these SNPs is feasible. A method for an exact quantitation based on these results is not realizable. These sequence variations were confirmed for a comprehensive cultivar collection of Arriba and CCN-51, for both bean and leaf samples.

Multi-objective Decision Based Available Transfer Capability in Deregulated Power System Using Heuristic Approaches

NASA Astrophysics Data System (ADS)

Pasam, Gopi Krishna; Manohar, T. Gowri

2016-09-01

Determination of available transfer capability (ATC) requires the use of experience, intuition and exact judgment in order to meet several significant aspects in the deregulated environment. Based on these points, this paper proposes two heuristic approaches to compute ATC. The first proposed heuristic algorithm integrates the five methods known as continuation repeated power flow, repeated optimal power flow, radial basis function neural network, back propagation neural network and adaptive neuro fuzzy inference system to obtain ATC. The second proposed heuristic model is used to obtain multiple ATC values. Out of these, a specific ATC value will be selected based on a number of social, economic, deregulated environmental constraints and related to specific applications like optimization, on-line monitoring, and ATC forecasting known as multi-objective decision based optimal ATC. The validity of results obtained through these proposed methods are scrupulously verified on various buses of the IEEE 24-bus reliable test system. The results presented and derived conclusions in this paper are very useful for planning, operation, maintaining of reliable power in any power system and its monitoring in an on-line environment of deregulated power system. In this way, the proposed heuristic methods would contribute the best possible approach to assess multiple objective ATC using integrated methods.

Repetition as the essence of life on this earth: music and genes.

PubMed

Ohno, S

1987-01-01

In prebiotic nucleic acid replication, templates appear to have been in short supply. A single round of tandem duplication of existing oligomers assured progressive extension of templates to the length adequate for encoding of polypeptide chains. Thus, the first set of coding sequences had to be repeats of base oligomers encoding polypeptide chains of various periodicities. On one hand, the readiness of these periodical polypeptide chains to assume alpha-helical and/or beta-sheet secondary structures contributed to the extremely rapid initial functional diversification of these polypeptide chains. It would be recalled that most, if not all, of the sugar-metabolizing enzymes had already achieved the inviolable functional competence before the division of prokaryotes from eukaryotes. On the other hand, a certain (dipeptidic?) of the peptidic periodicities was apparently chosen as the timekeeping unit by the biological clock. Musical compositions too apparently evolved originally as a timekeeping device. Accordingly, repetitiousness is evident in all musical compositions. Evolution of musical compositions from the early Baroque to the late Romantic parallels that of coding sequences from rather exact repeats of base oligomers to more complex modern coding sequences in which repetitious elements are less conspicuous and more varied. Inasmuch as the earth is governed by the hierarchy of periodicities (days, months and years), such reliance on periodicities is rather expected.

Balancing selection on the number of repeats in the ribosomal intergenic spacer present in naturally occurring yellow perch (Perca flavescens) populations.

PubMed

Bélanger-Lépine, Frédérique; Leung, Christelle; Glémet, Hélène; Angers, Bernard

2018-01-01

The ribosomal intergenic spacer (IGS), responsible for the rate of transcription of rRNA genes, is associated with the growth and fecundity of individuals. A previous study of IGS length variants in a yellow perch (Perca flavescens) population revealed the presence of two predominant alleles differing by 1 kb due to variation in the number of repeat units. This study aims to assess whether length variation of IGS is the result of selection in natural populations. Length variation of IGS and 11 neutral microsatellite loci were assessed in geographically distant yellow perch populations. Most populations displayed the very same IGS alleles; they did not differ in frequencies among populations and the F ST was not significantly different from zero. In contrast, diversity at microsatellite loci was high and differed among populations (F ST = 0.18). Selection test based on F ST identified IGS as a significant outlier from neutral expectations for population differentiation. Heterozygote excess was also detected in one specific cohort, suggesting temporal variation in the selection regime. While the exact mechanism remains to be specified, together the results of this study support the contention that balancing selection is acting to maintain two distinct IGS alleles in natural fish populations.

SMEX-Lite Modular Solar Array Architecture

NASA Technical Reports Server (NTRS)

Lyons, John

2002-01-01

For the most part, Goddard solar arrays have been custom designs that are unique to each mission. The solar panel design has been frozen prior to issuing an RFP for their procurement. There has typically been 6-9 months between RFP release and contract award, followed by an additional 24 months for performance of the contract. For Small Explorer (SMEX) missions, with three years between mission definition and launch, this has been a significant problem. The SMEX solar panels have been sufficiently small that the contract performance period has been reduced to 12-15 months. The bulk of this time is used up in the final design definition and fabrication of flight solar cell assemblies. Even so, it has been virtually impossible to have the spacecraft design at a level of maturity sufficient to freeze the solar panel geometry and release the RFP in time to avoid schedule problems with integrating the solar panels to the spacecraft. With that in mind, the SMEX-Lite project team developed a modular architecture for the assembly of solar arrays to greatly reduce the cost and schedule associated with the development of a mission- specific solar array. In the modular architecture, solar cells are fabricated onto small substrate panels. This modular panel (approximately 8.5" x 17" in this case) becomes the building block for constructing solar arrays for multiple missions with varying power requirements and geometrical arrangements. The mechanical framework that holds these modules together as a solar array is the only mission-unique design, changing in size and shape as required for each mission. There are several advantages to this approach. First, the typical solar array development cycle requires a mission unique design, procurement, and qualification including a custom qualification panel. With the modular architecture, a single qualification of the SMEX-Lite modules and the associated mechanical framework in a typical configuration provided a qualification by similarity to multiple missions. It then becomes possible to procure solar array modules in advance of mission definition and respond quickly and inexpensively to a selected mission's unique requirements. The solar array modular architecture allows the procurement of solar array modules before the array geometry has been frozen. This reduces the effect of procurement lead-time on the mission integration and test flow by as much as 50%. Second, by spreading the non-recurring costs over multiple missions, the cost per unit area is also reduced. In the case of the SMEX-Lite procurement, this reduction was by about one third of the cost per unit area compared to previous SMEX mission-unique procurements. Third, the modular architecture greatly facilitates the infusion of new solar cell technologies into flight programs as these technologies become available. New solar cell technologies need only be fabricated onto a standard-sized module to be incorporated into the next available mission. The modular solar array can be flown in a mixed configuration with some new and some standard cell technologies. Since each module has its own wiring terminals, the array can be arranged as desired electrically with little impact to cost and schedule. The solar array modular architecture does impose some additional constraints on systems and subsystem engineers. First, they must work with discrete solar array modules rather than size the array to fit exactly within an available envelope. The array area is constrained to an integer multiple of the module area. Second, the modular design is optimized for space radiation and thermal environments not greatly different from a typical SMEX LEO environment. For example, a mission with a highly elliptical orbit (e.g., Polar, SMEX/FAST) would require thicker coverglasses to protect the solar cells from the more intense radiation environment.

Can satellite-based monitoring techniques be used to quantify volcanic CO2 emissions?

NASA Astrophysics Data System (ADS)

Schwandner, Florian M.; Carn, Simon A.; Kuze, Akihiko; Kataoka, Fumie; Shiomi, Kei; Goto, Naoki; Popp, Christoph; Ajiro, Masataka; Suto, Hiroshi; Takeda, Toru; Kanekon, Sayaka; Sealing, Christine; Flower, Verity

2014-05-01

Since 2010, we investigate and improve possible methods to regularly target volcanic centers from space in order to detect volcanic carbon dioxide (CO2) point source anomalies, using the Japanese Greenhouse gas Observing SATellite (GOSAT). Our long-term goals are: (a) better spatial and temporal coverage of volcano monitoring techniques; (b) improvement of the currently highly uncertain global CO2 emission inventory for volcanoes, and (c) use of volcanic CO2 emissions for high altitude, strong point source emission and dispersion studies in atmospheric science. The difficulties posed by strong relief, orogenic clouds, and aerosols are minimized by a small field of view, enhanced spectral resolving power, by employing repeat target mode observation strategies, and by comparison to continuous ground based sensor network validation data. GOSAT is a single-instrument Earth observing greenhouse gas mission aboard JAXA's IBUKI satellite in sun-synchronous polar orbit. GOSAT's Fourier-Transform Spectrometer (TANSO-FTS) has been producing total column XCO2 data since January 2009, at a repeat cycle of 3 days, offering great opportunities for temporal monitoring of point sources. GOSAT's 10 km field of view can spatially integrate entire volcanic edifices within one 'shot' in precise target mode. While it doesn't have any spatial scanning or mapping capability, it does have strong spectral resolving power and agile pointing capability to focus on several targets of interest per orbit. Sufficient uncertainty reduction is achieved through comprehensive in-flight vicarious calibration, in close collaboration between NASA and JAXA. Challenges with the on-board pointing mirror system have been compensated for employing custom observation planning strategies, including repeat sacrificial upstream reference points to control pointing mirror motion, empirical individualized target offset compensation, observation pattern simulations to minimize view angle azimuth. Since summer 2010 we have conducted repeated target mode observations of now almost 40 persistently active global volcanoes and other point sources, including Etna (Italy), Mayon (Philippines), Hawaii (USA), Popocatepetl (Mexico), and Ambrym (Vanuatu), using GOSAT FTS SWIR data. In this presentation we will summarize results from over three years of measurements and progress toward understanding detectability with this method. In emerging collaboration with the Deep Carbon Observatory's DECADE program, the World Organization of Volcano Observatories (WOVO) global database of volcanic unrest (WOVOdat), and country specific observatories and agencies we see a growing potential for ground based validation synergies. Complementing the ongoing GOSAT mission, NASA is on schedule to launch its OCO-2 satellite in July 2014, which will provide higher spatial but lower temporal resolution. Further orbiting and geostationary satellite sensors are in planning at JAXA, NASA, and ESA.

Space Shuttle orbiter Columbia touches down at Edwards Air Force Base

NASA Image and Video Library

1981-04-14

S81-30744 (14 April 1981) --- The rear wheels of the space shuttle orbiter Columbia are about to touch down on Rogers Lake (a dry bed) at Edwards Air Force Base in southern California to successfully complete a stay in space of more than two days. Astronauts John W. Young, STS-1 commander, and Robert L. Crippen, pilot, are aboard the vehicle. The mission marked the first NASA flight to end with a wheeled landing and represents the beginning of a new age of spaceflight that will employ the same hardware repeatedly. Photo credit: NASA

Saturn/Titan Rendezvous: A Solar-Sail Aerocapture Mission

NASA Technical Reports Server (NTRS)

Matloff, Gregory L.; Taylor, Travis; Powell, Conley

2004-01-01

A low-mass Titan orbiter is proposed that uses conservative or optimistic solar sails for all post-Earth-escape propulsion. After accelerating the probe onto a trans-Saturn trajectory, the sail is used parachute style for Saturn capture during a pass through Saturn's outer atmosphere. If the apoapsis of the Saturn-capture orbit is appropriate, the aerocapture maneuver can later be repeated at Titan so that the spacecraft becomes a satellite of Titan. An isodensity-atmosphere model is applied to screen aerocapture trajectories. Huygens/Cassini should greatly reduce uncertainties regarding the upper atmospheres of Saturn and Titan.

The ENVISAT Atmospheric Chemistry mission (GOMOS, MIPAS and SCIAMACHY) - Instrument status and mission evolution

NASA Astrophysics Data System (ADS)

Niro, F.

2009-04-01

The ENVISAT ESA's satellite was launched on a polar orbit on March 2002. It carries on-board three atmospheric chemistry instruments: GOMOS, MIPAS and SCIAMACHY [1]. At the present time, although the mission expected lifetime of 5 years has been already exceeded, all the payload modules are in good to excellent status. The only limiting factor is the available fuel that is used for orbit control manoeuvre. Recently a new strategy was proposed [2] that will allow to save fuel and to extend the mission up to 2013. Following this strategy, the altitude of the orbit will be lowered by 17 km starting from end of 2010 and the inclination will be allowed to drift. The new orbit scenario will result in a new repeating cycle with a variation of the Mean Local Solar Time (MLST). This will have an impact on both the in-flight operations, on the science data and on the mission. The simulations carried out for the atmospheric chemistry instruments show that the new orbit strategy will neither have a significant impact in the instrument operations nor on the quality of the science data. Therefore we expect that the atmospheric mission will continue nominally until the end of the platform life time, providing to the scientist a unique dataset of the most important geophysical parameters (e.g., trace gases, clouds, and aerosol) spanning a time interval of about 11 years. The aim of this paper is to review the overall ENVISAT atmospheric mission status for the past, present and future. The evolution of the instrument performances since launch will be analyzed with focus on the life-limited items monitoring. The tuning of the instrument in-flight operations decided to cope with instrument degradation or scientific needs will be described. The lessons learned on how to operate and monitor the instruments will be highlighted. Finally the expected evolution of the instrument performances until the ENVISAT end-of-life will be discussed. [1] H. Nett, J. Frerick, T. Paulsen, and G. Levrini, "The atmospheric instruments and their applications: GOMOS, MIPAS and SCIAMACHY", ESA Bulletin (ISSN 0376-4265), No. 106, p. 77 - 87 (2001) [2] J. Frerick, B. Duesmann, and M. Canela, "2010 and beyond - The ENVISAT mission extension", Proc. ‘Envisat Symposium 2007', Montreux, Switzerland, 23-27 April 2007 (ESA SP-636, July 2007)

The ENVISAT Atmospheric Chemistry mission (GOMOS, MIPAS and SCIAMACHY) -Instrument status and mission evolution

NASA Astrophysics Data System (ADS)

Dehn, Angelika

The ENVISAT ESA's satellite was launched on a polar orbit on March 2002. It carries on-board three atmospheric chemistry instruments: GOMOS, MIPAS and SCIAMACHY [1]. At the present time, although the mission expected lifetime of 5 years has been already exceeded, all the payload modules are in good to excellent status. The only limiting factor is the available fuel that is used for orbit control manoeuvre. A new strategy was proposed [2] that will allow to save fuel and to extend the mission up to 2013. Following this strategy, the altitude of the orbit will be lowered by 17 km starting from end of 2010 and the inclination will be allowed to drift. The new orbit scenario will result in a new repeating cycle with a variation of the Mean Local Solar Time (MLST). This will have an impact on both the in-flight operations, on the science data and on the mission. The simulations carried out for the atmospheric chemistry instruments show that the new orbit strategy will neither have a significant impact in the instrument operations nor on the quality of the science data. Therefore we expect that the atmospheric mission will continue nominally until the end of the platform life time, providing to the scientist a unique dataset of the most important geophysical parameters (e.g., trace gases, clouds, and aerosol) spanning a time interval of about 11 years. The aim of this paper is to review the overall ENVISAT atmospheric mission status for the past, present and future. The evolution of the instrument performances since launch will be analyzed with focus on the life-limited items monitoring. The tuning of the instrument in-flight operations decided to cope with instrument degradation or scientific needs will be described. The lessons learned on how to operate and monitor the instruments will be highlighted. Finally the expected evolution of the instrument performances until the ENVISAT end-of-life will be discussed. [1] H. Nett, J. Frerick, T. Paulsen, and G. Levrini, "The atmospheric instruments and their applications: GOMOS, MIPAS and SCIAMACHY", ESA Bulletin (ISSN 0376-4265), No. 106, p. 77 -87 (2001) [2] J. Frerick, B. Duesmann, and M. Canela, "2010 and beyond -The ENVISAT mission extension", Proc. `Envisat Symposium 2007', Montreux, Switzerland, 23-27 April 2007 (ESA SP-636, July 2007)

Repeatability and Accuracy of Exoplanet Eclipse Depths Measured with Post-cryogenic Spitzer

NASA Astrophysics Data System (ADS)

Ingalls, James G.; Krick, J. E.; Carey, S. J.; Stauffer, John R.; Lowrance, Patrick J.; Grillmair, Carl J.; Buzasi, Derek; Deming, Drake; Diamond-Lowe, Hannah; Evans, Thomas M.; Morello, G.; Stevenson, Kevin B.; Wong, Ian; Capak, Peter; Glaccum, William; Laine, Seppo; Surace, Jason; Storrie-Lombardi, Lisa

2016-08-01

We examine the repeatability, reliability, and accuracy of differential exoplanet eclipse depth measurements made using the InfraRed Array Camera (IRAC) on the Spitzer Space Telescope during the post-cryogenic mission. We have re-analyzed an existing 4.5 μm data set, consisting of 10 observations of the XO-3b system during secondary eclipse, using seven different techniques for removing correlated noise. We find that, on average, for a given technique, the eclipse depth estimate is repeatable from epoch to epoch to within 156 parts per million (ppm). Most techniques derive eclipse depths that do not vary by more than a factor 3 of the photon noise limit. All methods but one accurately assess their own errors: for these methods, the individual measurement uncertainties are comparable to the scatter in eclipse depths over the 10 epoch sample. To assess the accuracy of the techniques as well as to clarify the difference between instrumental and other sources of measurement error, we have also analyzed a simulated data set of 10 visits to XO-3b, for which the eclipse depth is known. We find that three of the methods (BLISS mapping, Pixel Level Decorrelation, and Independent Component Analysis) obtain results that are within three times the photon limit of the true eclipse depth. When averaged over the 10 epoch ensemble, 5 out of 7 techniques come within 60 ppm of the true value. Spitzer exoplanet data, if obtained following current best practices and reduced using methods such as those described here, can measure repeatable and accurate single eclipse depths, with close to photon-limited results.

Rover mast calibration, exact camera pointing, and camara handoff for visual target tracking

NASA Technical Reports Server (NTRS)

Kim, Won S.; Ansar, Adnan I.; Steele, Robert D.

2005-01-01

This paper presents three technical elements that we have developed to improve the accuracy of the visual target tracking for single-sol approach-and-instrument placement in future Mars rover missions. An accurate, straightforward method of rover mast calibration is achieved by using a total station, a camera calibration target, and four prism targets mounted on the rover. The method was applied to Rocky8 rover mast calibration and yielded a 1.1-pixel rms residual error. Camera pointing requires inverse kinematic solutions for mast pan and tilt angles such that the target image appears right at the center of the camera image. Two issues were raised. Mast camera frames are in general not parallel to the masthead base frame. Further, the optical axis of the camera model in general does not pass through the center of the image. Despite these issues, we managed to derive non-iterative closed-form exact solutions, which were verified with Matlab routines. Actual camera pointing experiments aver 50 random target image paints yielded less than 1.3-pixel rms pointing error. Finally, a purely geometric method for camera handoff using stereo views of the target has been developed. Experimental test runs show less than 2.5 pixels error on high-resolution Navcam for Pancam-to-Navcam handoff, and less than 4 pixels error on lower-resolution Hazcam for Navcam-to-Hazcam handoff.

Drinking Water Database

NASA Technical Reports Server (NTRS)

Murray, ShaTerea R.

2004-01-01

This summer I had the opportunity to work in the Environmental Management Office (EMO) under the Chemical Sampling and Analysis Team or CS&AT. This team s mission is to support Glenn Research Center (GRC) and EM0 by providing chemical sampling and analysis services and expert consulting. Services include sampling and chemical analysis of water, soil, fbels, oils, paint, insulation materials, etc. One of this team s major projects is the Drinking Water Project. This is a project that is done on Glenn s water coolers and ten percent of its sink every two years. For the past two summers an intern had been putting together a database for this team to record the test they had perform. She had successfully created a database but hadn't worked out all the quirks. So this summer William Wilder (an intern from Cleveland State University) and I worked together to perfect her database. We began be finding out exactly what every member of the team thought about the database and what they would change if any. After collecting this data we both had to take some courses in Microsoft Access in order to fix the problems. Next we began looking at what exactly how the database worked from the outside inward. Then we began trying to change the database but we quickly found out that this would be virtually impossible.

Cryogenic filter wheel design for an infrared instrument

NASA Astrophysics Data System (ADS)

Azcue, Joaquín.; Villanueva, Carlos; Sánchez, Antonio; Polo, Cristina; Reina, Manuel; Carretero, Angel; Torres, Josefina; Ramos, Gonzalo; Gonzalez, Luis M.; Sabau, Maria D.; Najarro, Francisco; Pintado, Jesús M.

2014-09-01

In the last two decades, Spain has built up a strong IR community which has successfully contributed to space instruments, reaching Co-PI level in the SPICA mission (Space Infrared Telescope for Cosmology and Astrophysics). Under the SPICA mission, INTA, focused on the SAFARI instrument requirements but highly adaptable to other missions has designed a cryogenic low dissipation filter wheel with six positions, taking as starting point the past experience of the team with the OSIRIS instrument (ROSETTA mission) filter wheels and adapting the design to work at cryogenic temperatures. One of the main goals of the mechanism is to use as much as possible commercial components and test them at cryogenic temperature. This paper is focused on the design of the filter wheel, including the material selection for each of the main components of the mechanism, the design of elastic mount for the filter assembly, a positioner device designed to provide positional accuracy and repeatability to the filter, allowing the locking of the position without dissipation. In order to know the position of the wheel on every moment a position sensor based on a Hall sensor was developed. A series of cryogenic tests have been performed in order to validate the material configuration selected, the ball bearing lubrication and the selection of the motor. A stepper motor characterization campaign was performed including heat dissipation measurements. The result is a six position filter wheel highly adaptable to different configurations and motors using commercial components. The mechanism was successfully tested at INTA facilities at 20K at breadboard level.

New Method for Astrometric Measurements in Space Mission, JASMINE.

NASA Astrophysics Data System (ADS)

Yano, T.; Gouda, N.; Yamada, Y.

2006-08-01

We present a new method for measuring positions of stars in the Milky Way Galaxy by astrometric satellite, JASMINE, which is in progress at the National Astronomical Observatory of Japan. JASMINE is the acronym of the Japan Astrometry Satellite Mission for Infrared (z-band : 0.9 micron) Exploration, and is planned to be launched around 2015 The main objective of JASMINE is to study the fundamental structure and evolution of the bulge components of the Milky Way Galaxy. In order to accomplish these objectives, JASMINE will measure trigonometric parallaxes, positions and proper motions of about a few million stars during the observational program, with the precision of 10 microarcsec at z =14mag. The telescope of JASMINE has just one field of view, which is different from other astrometric satellites like Hipparcos and GAIA, that have two fields of view with large angle. These satellites, Hipparcos and GAIA, scan along the great circle with the spin axis perpendicular to both two fields of view to estimate the relative positions of stars on the great circle. They scan many different great circles to observe all the sky. On the other hand, JASMINE will take overlapping fields of view without any gaps to survey an area of about 20deg*10deg. Accordingly survey area covers the region of about 20deg*10deg in the bulge component. JASMINE will continue the above procedure for observing the area during the mission life. As a consequence, JASMINE will observe the restricted regions around the Galactic bulge and sweep repeatedly. The mission life is planned to be 5 years.

Crew-Aided Autonomous Navigation

NASA Technical Reports Server (NTRS)

Holt, Greg N.

2015-01-01

A sextant provides manual capability to perform star/planet-limb sightings and offers a cheap, simple, robust backup navigation source for exploration missions independent from the ground. Sextant sightings from spacecraft were first exercised in Gemini and flew as the lost-communication backup for all Apollo missions. This study characterized error sources of navigation-grade sextants for feasibility of taking star and planetary limb sightings from inside a spacecraft. A series of similar studies was performed in the early/mid-1960s in preparation for Apollo missions. This study modernized and updated those findings in addition to showing feasibility using Linear Covariance analysis techniques. The human eyeball is a remarkable piece of optical equipment and provides many advantages over camera-based systems, including dynamic range and detail resolution. This technique utilizes those advantages and provides important autonomy to the crew in the event of lost communication with the ground. It can also provide confidence and verification of low-TRL automated onboard systems. The technique is extremely flexible and is not dependent on any particular vehicle type. The investigation involved procuring navigation-grade sextants and characterizing their performance under a variety of conditions encountered in exploration missions. The JSC optical sensor lab and Orion mockup were the primary testing locations. For the accuracy assessment, a group of test subjects took sextant readings on calibrated targets while instrument/operator precision was measured. The study demonstrated repeatability of star/planet-limb sightings with bias and standard deviation around 10 arcseconds, then used high-fidelity simulations to verify those accuracy levels met the needs for targeting mid-course maneuvers in preparation for Earth reen.

A burst chasing x-ray polarimeter

NASA Astrophysics Data System (ADS)

Hill, Joanne E.; Barthelmy, Scott; Black, J. Kevin; Deines-Jones, Philip; Jahoda, Keith; Sakamoto, Takanori; Kaaret, Philip; McConnell, Mark L.; Bloser, Peter F.; Macri, John R.; Legere, Jason S.; Ryan, James M.; Smith, Billy R., Jr.; Zhang, Bing

2007-09-01

Gamma-ray bursts are one of the most powerful explosions in the universe and have been detected out to distances of almost 13 billion light years. The exact origin of these energetic explosions is still unknown but the resulting huge release of energy is thought to create a highly relativistic jet of material and a power-law distribution of electrons. There are several theories describing the origin of the prompt GRB emission that currently cannot be distinguished. Measurements of the linear polarization would provide unique and important constraints on the mechanisms thought to drive these powerful explosions. We present the design of a sensitive, and extremely versatile gamma-ray burst polarimeter. The instrument is a photoelectric polarimeter based on a time-projection chamber. The photoelectric time-projection technique combines high sensitivity with broad band-pass and is potentially the most powerful method between 2 and 100 keV where the photoelectric effect is the dominant interaction process. We present measurements of polarized and unpolarized X-rays obtained with a prototype detector and describe the two mission concepts; the Gamma-Ray Burst Polarimeter (GRBP) for the U.S. Naval Academy satellite MidSTAR-2, and the Low Energy Polarimeter (LEP) onboard POET, a broadband polarimetry concept for a small explorer mission.

Connecting kinematic and dynamic reference frames by D-VLBI

NASA Astrophysics Data System (ADS)

Schuh, Harald; Plank, Lucia; Madzak, Matthias; Böhm, Johannes

2012-08-01

In geodetic and astrometric practice, terrestrial station coordinates are usually provided in the kinematic International Terrestrial Reference Frame (ITRF) and radio source coordinates in the International Celestial Reference Frame (ICRF), whereas measurements of space probes such as satellites and spacecrafts, or planetary ephemerides rest upon dynamical theories. To avoid inconsistencies and errors during measurement and calculation procedures, exact frame ties between quasi - inertial, kinematic and dynamic reference frames have to be secured. While the Earth Orientation Parameters (EOP), e.g. measured by VLBI, link the ITRF to the ICRF, the ties with the dynamic frames can be established with the differential Very Long Baseline Interferometry (D - VLBI) method. By observing space probes alternately t o radio sources, the relative position of the targets to each other on the sky can be determined with high accuracy. While D - VLBI is a common technique in astrophysics (source imaging) and deep space navigation, just recently there have been several effort s to use it for geodetic purposes. We present investigations concerning possible VLBI observations to satellites. This includes the potential usage of available GNNS satellites as well as specifically designed missions, as e.g. the GRASP mission proposed b y JPL/NASA and an international consortium, where the aspect of co - location in space of various techniques (VLBI, SLR, GNSS, DORIS) is the main focus.

Scientific objectives and selection of targets for the SMART-1 Infrared Spectrometer (SIR)

USGS Publications Warehouse

Basilevsky, A.T.; Keller, H.U.; Nathues, A.; Mall, U.; Hiesinger, H.; Rosiek, M.

2004-01-01

The European SMART-1 mission to the Moon, primarily a testbed for innovative technologies, was launched in September 2003 and will reach the Moon in 2005. On board are several scientific instruments, including the point-spectrometer SMART-1 Infrared Spectrometer (SIR). Taking into account the capabilities of the SMART-1 mission and the SIR instrument in particular, as well as the open questions in lunar science, a selection of targets for SIR observations has been compiled. SIR can address at least five topics: (1) Surface/regolith processes; (2) Lunar volcanism; (3) Lunar crust structure; (4) Search for spectral signatures of ices at the lunar poles; and (5) Ground truth and study of geometric effects on the spectral shape. For each topic we will discuss specific observation modes, necessary to achieve our scientific goals. The majority of SIR targets will be observed in the nadir-tracking mode. More than 100 targets, which require off-nadir pointing and off-nadir tracking, are planned. It is expected that results of SIR observations will significantly increase our understanding of the Moon. Since the exact arrival date and the orbital parameters of the SMART-1 spacecraft are not known yet, a more detailed planning of the scientific observations will follow in the near future. ?? 2004 Elsevier Ltd. All rights reserved.

JASMINE: constructor of the dynamical structure of the Galactic bulge

NASA Astrophysics Data System (ADS)

Gouda, N.; Kobayashi, Y.; Yamada, Y.; Yano, T.; Tsujimoto, T.; Suganuma, M.; Niwa, Y.; Yamauchi, M.

2008-07-01

We introduce a Japanese space astrometry project which is called JASMINE. JASMINE (Japan Astrometry Satellite Mission for INfrared Exploration) will measure distances and tangential motions of stars in the Galactic bulge with yet unprecedented precision. JASMINE will operate in z-band whose central wavelength is 0.9 micron. It will measure parallaxes, positions with accuracy of about 10 micro-arcsec and proper motions with accuracy of about 10 micro- arcsec/year for the stars brighter than z=14 mag. The number of stars observed by JASMINE with high accuracy of parallaxes in the Galactic bulge is much larger than that observed in other space astrometry projects operating in optical bands. With the completely new “map of the Galactic bulge” including motions of bulge stars, we expect that many new exciting scientific results will be obtained in studies of the Galactic bulge. One of them is the construction of the dynamical structure of the Galactic bulge. Kinematics and distance data given by JASMINE are the closest approach to a view of the exact dynamical structure of the Galactic bulge. Presently, JASMINE is in a development phase, with a target launch date around 2016. We comment on the outline of JASMINE mission, scientific targets and a preliminary design of JASMINE in this paper.

Sublimation Formation on Mercury

NASA Image and Video Library

2017-12-08

Located in the crater Eminescu, this high-resolution image shows part of the mountainous peak ring, as well as an example of the extensive formation of hollows located within the crater. Hollows maintain an air of mystery in the realm of planetary science. Though the exact formation mechanism is unknown, most scientists agree sublimation of volatiles holds the answer. This image highlights the prevalence of these hollows on and around the peak ring, as well as captures the beauty of such enigmatic formations. This image was acquired as a high-resolution targeted observation. Targeted observations are images of a small area on Mercury's surface at resolutions much higher than the 200-meter/pixel morphology base map. It is not possible to cover all of Mercury's surface at this high resolution, but typically several areas of high scientific interest are imaged in this mode each week. Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Carnegie Institution of Washington NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

A Burst Chasing X-ray Polarimeter

NASA Technical Reports Server (NTRS)

Hill, Joanne E.; Barthelmy, Scott; Black, J. kevin; Deines-Jones, Philip; Jahoda, Keith; Sakamoto, Takanori; Kaaret, Philip; McConnell, Mark L.; Bloser, Peter F.; Macri, John R.;

A Burst Chasing X-ray Polarimeter

NASA Technical Reports Server (NTRS)

Hill, Joanne; Hill, Joe; Barthelmy, S.; Black, K.; Deines-Jones, P.; Jahoda, K.; Sakamoto, T.; Kaaret, P.; McConnell, M.; Bloser, P.;

KSC-08pd0005

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, Bob Arp, an aerospace technician with the United Launch Alliance, inserts a wire from an electrical harness onto the pin of a replacement feed-through connector during preparations to solder the pins to the socket of the connector. The connector will be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technician performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and was specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd0002

NASA Image and Video Library

2008-01-04

KENNEDY SPACE CENTER, FLA. -- At a lab at NASA's Kennedy Space Center, Kevin Wyckoff, an aerospace technician with the United Launch Alliance, examines an electrical wiring harness. The harness will be inserted into a replacement feed-through connector during preparations to solder the pins to the socket of the connector. The connector will later be installed in the external fuel tank for space shuttle Atlantis' STS-122 mission. The technician performed this exacting task on the Centaur upper stage for Atlas and Titan launches in 1994 and was specifically chosen for the task. Soldering the connector pins and sockets together addresses the most likely cause of a problem in the engine cutoff sensor system, or ECO system. Some of the tank's ECO sensors failed during propellant tanking for launch attempts on Dec. 6 and Dec. 9. Results of a tanking test on Dec. 18 pointed to an open circuit in the feed-through connector wiring, which is located at the base of the tank. The feed-through connector passes the wires from the inside of the tank to the outside. After the soldering is completed and the connector is reinstalled, shuttle program managers will decide on how to proceed. The launch date for mission STS-122 is under review. Photo credit: NASA/Kim Shiflett

Molecular cytogenetic analysis of Xq critical regions in premature ovarian failure

PubMed Central

2013-01-01

Background One of the frequent reasons for unsuccessful conception is premature ovarian failure/primary ovarian insufficiency (POF/POI) that is defined as the loss of functional follicles below the age of 40 years. Among the genetic causes the most common one involves the X chromosome, as in Turner syndrome, partial X deletion and X-autosome translocations. Here we report a case of a 27-year-old female patient referred to genetic counselling because of premature ovarian failure. The aim of this case study to perform molecular genetic and cytogenetic analyses in order to identify the exact genetic background of the pathogenic phenotype. Results For premature ovarian failure disease diagnostics we performed the Fragile mental retardation 1 gene analysis using Southern blot technique and Repeat Primed PCR in order to identify the relationship between the Fragile mental retardation 1 gene premutation status and the premature ovarion failure disease. At this early onset, the premature ovarian failure affected patient we detected one normal allele of Fragile mental retardation 1 gene and we couldn’t verify the methylated allele, therefore we performed the cytogenetic analyses using G-banding and fluorescent in situ hybridization methods and a high resolution molecular cytogenetic method, the array comparative genomic hybridization technique. For this patient applying the G-banding, we identified a large deletion on the X chromosome at the critical region (ChrX q21.31-q28) which is associated with the premature ovarian failure phenotype. In order to detect the exact breakpoints, we used a special cytogenetic array ISCA plus CGH array and we verified a 67.355 Mb size loss at the critical region which include total 795 genes. Conclusions We conclude for this case study that the karyotyping is definitely helpful in the evaluation of premature ovarian failure patients, to identify the non submicroscopic chromosomal rearrangement, and using the array CGH technique we can contribute to the most efficient detection and mapping of exact deletion breakpoints of the deleted Xq region. PMID:24359613

Kolkata Paise Restaurant Problem and the Cyclically Fair Norm

NASA Astrophysics Data System (ADS)

Banerjee, Priyodorshi; Mitra, Manipushpak; Mukherjee, Conan

In this paper we revisit the Kolkata Paise Restaurant problem by allowing for a more general (but common) preference of the n customers defined over the set of n restaurants. This generalization allows for the possibility that each pure strategy Nash equilibrium differs from the Pareto efficient allocation. By assuming that n is small and by allowing for mutual interaction across all customers we design strategies to sustain cyclically fair norm as a sub-game perfect equilibrium of the Kolkata Paise Restaurant problem. We have a cyclically fair norm if n strategically different Pareto efficient strategies are sequentially sustained in a way such that each customer gets serviced in all the n restaurants exactly once between periods 1 and n and then again the same process is repeated between periods (n+1) and 2n and so on.

Seasonal flows on warm Martian slopes

USGS Publications Warehouse

McEwen, A.S.; Ojha, L.; Dundas, C.M.; Mattson, S.S.; Byrne, S.; Wray, J.J.; Cull, S.C.; Murchie, S.L.; Thomas, N.; Gulick, V.C.

2011-01-01

Water probably flowed across ancient Mars, but whether it ever exists as a liquid on the surface today remains debatable. Recurring slope lineae (RSL) are narrow (0.5 to 5 meters), relatively dark markings on steep (25?? to 40??) slopes; repeat images from the Mars Reconnaissance Orbiter High Resolution Imaging Science Experiment show them to appear and incrementally grow during warm seasons and fade in cold seasons. They extend downslope from bedrock outcrops, often associated with small channels, and hundreds of them form in some rare locations. RSL appear and lengthen in the late southern spring and summer from 48??S to 32??S latitudes favoring equator-facing slopes, which are times and places with peak surface temperatures from ???250 to 300 kelvin. Liquid brines near the surface might explain this activity, but the exact mechanism and source of water are not understood.

Ultimate fate of constrained voters

NASA Astrophysics Data System (ADS)

Vazquez, F.; Redner, S.

2004-09-01

We examine the ultimate fate of individual opinions in a socially interacting population of leftists, centrists and rightists. In an elemental interaction between agents, a centrist and a leftist can both become centrists or both become leftists with equal rates (and similarly for a centrist and a rightist). However leftists and rightists do not interact. This interaction step between pairs of agents is applied repeatedly until the system can no longer evolve. In the mean-field limit, we determine the exact probability that the system reaches consensus (either leftist, rightist or centrist) or a frozen mixture of leftists and rightists as a function of the initial composition of the population. We also determine the mean time until the final state is reached. Some implications of our results for the ultimate fate in a limit of the Axelrod model are discussed.

[Extemporaneous examination in lung pathology: the pathologist's view].

PubMed

Molinié, V; Duchatelle, V; Abbey-Tobby, A; Balaton, A

2012-06-01

Extemporaneous examination of a thoracopulmonary lesion has an unquestionable interest when pre-surgical diagnostic workup has not allowed determining its exact nature. This examination, the sole objective of which is to guide the surgical approach, is especially important in lung pathology, due to the limited non-surgical access to thoracic lesions and the morbidity and mortality of repeated surgery. Its yield as a decision-making procedure is of utmost importance in many clinical situations, and a close collaboration between thoracic surgeons and pathologists is required to ensure its quality, in a context of mutual confidence that requires time and experience. After a presentation of the indications and practical modalities of extemporaneous examination, we will underline its limitations and insist on difficult situations for the pathologist and inadequate indications. Copyright © 2012 SPLF. Published by Elsevier Masson SAS. All rights reserved.

A novel Markov Blanket-based repeated-fishing strategy for capturing phenotype-related biomarkers in big omics data.

PubMed

Li, Hongkai; Yuan, Zhongshang; Ji, Jiadong; Xu, Jing; Zhang, Tao; Zhang, Xiaoshuai; Xue, Fuzhong

2016-03-09

We propose a novel Markov Blanket-based repeated-fishing strategy (MBRFS) in attempt to increase the power of existing Markov Blanket method (DASSO-MB) and maintain its advantages in omic data analysis. Both simulation and real data analysis were conducted to assess its performances by comparing with other methods including χ(2) test with Bonferroni and B-H adjustment, least absolute shrinkage and selection operator (LASSO) and DASSO-MB. A serious of simulation studies showed that the true discovery rate (TDR) of proposed MBRFS was always close to zero under null hypothesis (odds ratio = 1 for each SNPs) with excellent stability in all three scenarios of independent phenotype-related SNPs without linkage disequilibrium (LD) around them, correlated phenotype-related SNPs without LD around them, and phenotype-related SNPs with strong LD around them. As expected, under different odds ratio and minor allel frequency (MAFs), MBRFS always had the best performances in capturing the true phenotype-related biomarkers with higher matthews correlation coefficience (MCC) for all three scenarios above. More importantly, since proposed MBRFS using the repeated fishing strategy, it still captures more phenotype-related SNPs with minor effects when non-significant phenotype-related SNPs emerged under χ(2) test after Bonferroni multiple correction. The various real omics data analysis, including GWAS data, DNA methylation data, gene expression data and metabolites data, indicated that the proposed MBRFS always detected relatively reasonable biomarkers. Our proposed MBRFS can exactly capture the true phenotype-related biomarkers with the reduction of false negative rate when the phenotype-related biomarkers are independent or correlated, as well as the circumstance that phenotype-related biomarkers are associated with non-phenotype-related ones.

Projection of controlled repeatable real-time moving targets to test and evaluate motion imagery quality

NASA Astrophysics Data System (ADS)

Scopatz, Stephen D.; Mendez, Michael; Trent, Randall

2015-05-01

The projection of controlled moving targets is key to the quantitative testing of video capture and post processing for Motion Imagery. This presentation will discuss several implementations of target projectors with moving targets or apparent moving targets creating motion to be captured by the camera under test. The targets presented are broadband (UV-VIS-IR) and move in a predictable, repeatable and programmable way; several short videos will be included in the presentation. Among the technical approaches will be targets that move independently in the camera's field of view, as well targets that change size and shape. The development of a rotating IR and VIS 4 bar target projector with programmable rotational velocity and acceleration control for testing hyperspectral cameras is discussed. A related issue for motion imagery is evaluated by simulating a blinding flash which is an impulse of broadband photons in fewer than 2 milliseconds to assess the camera's reaction to a large, fast change in signal. A traditional approach of gimbal mounting the camera in combination with the moving target projector is discussed as an alternative to high priced flight simulators. Based on the use of the moving target projector several standard tests are proposed to provide a corresponding test to MTF (resolution), SNR and minimum detectable signal at velocity. Several unique metrics are suggested for Motion Imagery including Maximum Velocity Resolved (the measure of the greatest velocity that is accurately tracked by the camera system) and Missing Object Tolerance (measurement of tracking ability when target is obscured in the images). These metrics are applicable to UV-VIS-IR wavelengths and can be used to assist in camera and algorithm development as well as comparing various systems by presenting the exact scenes to the cameras in a repeatable way.

Arabidopsis leucine-rich repeat extensin (LRX) proteins modify cell wall composition and influence plant growth.

PubMed

Draeger, Christian; Ndinyanka Fabrice, Tohnyui; Gineau, Emilie; Mouille, Grégory; Kuhn, Benjamin M; Moller, Isabel; Abdou, Marie-Therese; Frey, Beat; Pauly, Markus; Bacic, Antony; Ringli, Christoph

2015-06-24

Leucine-rich repeat extensins (LRXs) are extracellular proteins consisting of an N-terminal leucine-rich repeat (LRR) domain and a C-terminal extensin domain containing the typical features of this class of structural hydroxyproline-rich glycoproteins (HRGPs). The LRR domain is likely to bind an interaction partner, whereas the extensin domain has an anchoring function to insolubilize the protein in the cell wall. Based on the analysis of the root hair-expressed LRX1 and LRX2 of Arabidopsis thaliana, LRX proteins are important for cell wall development. The importance of LRX proteins in non-root hair cells and on the structural changes induced by mutations in LRX genes remains elusive. The LRX gene family of Arabidopsis consists of eleven members, of which LRX3, LRX4, and LRX5 are expressed in aerial organs, such as leaves and stem. The importance of these LRX genes for plant development and particularly cell wall formation was investigated. Synergistic effects of mutations with gradually more severe growth retardation phenotypes in double and triple mutants suggest a similar function of the three genes. Analysis of cell wall composition revealed a number of changes to cell wall polysaccharides in the mutants. LRX3, LRX4, and LRX5, and most likely LRX proteins in general, are important for cell wall development. Due to the complexity of changes in cell wall structures in the lrx mutants, the exact function of LRX proteins remains to be determined. The increasingly strong growth-defect phenotypes in double and triple mutants suggests that the LRX proteins have similar functions and that they are important for proper plant development.

The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis.

PubMed

Du, Yanlei; Nie, Yuqiang; Li, Yuyuan; Wan, Yu-Jui Y

2011-09-01

Dopamine transporter gene (SLC6A3) represents a promising candidate involved in the development of alcoholism. This study aimed to explore the association between the 9-repeat allele (A9) of a 40-bp variable number tandem repeat (VNTR) polymorphism in the 3' un-translated region (3' UTR) of the SLC6A3 gene and alcoholism. The SLC6A3 VNTR was genotyped by PCR in unrelated Mexican Americans including 337 controls and 365 alcoholics. Pearson's chi-square test or Fisher's exact test was used to compare the genotype and allele distribution. Meta-analyses were performed for population-based case-control association studies of the SLC6A3 VNTR polymorphism with alcoholism. Data were analyzed under random effect models with the Comprehensive Meta-analysis (v.2) statistical software package. In Mexican Americans, no significant difference was found in allele and genotype distribution between controls and alcoholics or between controls and alcoholics with alcohol withdrawal seizure (AWS) or delirium tremens (DT) (unadjusted p > 0.05). A total of 13 research articles were included in the meta-analyses. No significant difference of the SLC6A3 VNTR A9 was noted between controls and alcoholics at the genotypic and allelic level when all ethnic populations, only Caucasian populations, or only Asian populations were considered (p > 0.05). Significant associations were observed between SLC6A3 VNTR A9 and alcoholics with AWS or DT at the genotypic as well as allelic level when all ethnic populations or only Caucasian populations were considered (p < 0.05, OR 1.5-2.1). Meta-analyses suggest a possible association between the SLC6A3 VNTR A9 and alcoholic subgroup with AWS or DT. 2011 by the Research Society on Alcoholism.

NASA Activity Update for the 2013 Unmanned Vehicle Systems International (UVSI) Yearbook

NASA Technical Reports Server (NTRS)

Bauer, Jeffrey E.

2013-01-01

This year s report offers a high level perspective on some of the UAS related activities in which NASA is involved, both internal and external to the agency. Internally, NASA issued UAS operational policy on certification of NASA UAS and aircrew. A team of NASA UAS experts and operators analyzed all current procedures and best practices to design the policy. An update to the agencies Aircraft Operations Management Manual incorporated a new chapter to address UAS planning, preflight operations, flight operations, flight crew requirements, airworthiness and flight safety reviews. NASA UAS are classified into three categories based on weight and airspeed. Aircrews, including observers, are classified by how they interface with the UAS, and the policy defines qualifications, training, and currency. The NASA flight readiness approval process identifies risks and mitigations in order to reduce the likelihood and/or consequence of the risk to an acceptable level. The UAS operations process incorporates all aspects of airworthiness, flight standards and range safety exactly the same processes used for NASA manned aircraft operations. NASA has two internal organizations that routinely operate UAS. The Science Mission Directorate utilizes UAS as part of its Airborne Science Program and is the most frequent operator of NASA UAS in both national and international airspace. The Aeronautics Research Mission Directorate conducts UAS flight operations in addition to conducting research important to the UAS community. This past year the Science Mission Directorate supported the Hurricane and Severe Storm Sentimental (HS3) Mission with two NASA Global Hawk platforms. HS3 is a five-year mission specifically targeted to investigate the processes that underlie hurricane formation. During the 2012 portion of this mission the Global Hawk overflew hurricanes Leslie and Nadine in the Atlantic Ocean completing 6 flights and accumulating more than 148 flight hours. Another multi-year mission was initiated last year when the Sensor Integrated Environmental Remote Research Aircraft (SIERRA) UAS began surveying faults in California s Surprise Valley. A team of scientists and engineers from the United States Geological Survey (USGS), NASA Ames Research Center, Central Washington University, and Carnegie Mellon University will measure magnetic fields using ground surveys and the SIERRA to map the geophysics below the surface of Surprise Valley. The data collected will be used to generate 3D maps of the geophysical data of the area. The Aeronautics Mission Directorate continues its collaboration with Boeing to conduct UAS flight operations of the X-48C, a modified version of the X-48B originally built by Cranfield Aerospace, United Kingdom. The Aeronautics Mission Directorate utilizes vehicles of this size for a wide variety of research studies. Most of these operations are conducted within restricted airspace. The Aeronautics Research Mission Directorate also sponsors the UAS in the National Airspace System (NAS) Project, which is working in close cooperation with the Federal Aviation Administration (FAA) to address critical challenges associated with routine UAS operations in civil airspace. The project is focused on separation assurance and collision avoidance systems and algorithms, command and control for non-military operations including spectrum allocation requirements, human system interaction issues, and safety and certification topics.

The Filtered Abel Transform and Its Application in Combustion Diagnostics

NASA Technical Reports Server (NTRS)

Simons, Stephen N. (Technical Monitor); Yuan, Zeng-Guang

2003-01-01

Many non-intrusive combustion diagnosis methods generate line-of-sight projections of a flame field. To reconstruct the spatial field of the measured properties, these projections need to be deconvoluted. When the spatial field is axisymmetric, commonly used deconvolution method include the Abel transforms, the onion peeling method and the two-dimensional Fourier transform method and its derivatives such as the filtered back projection methods. This paper proposes a new approach for performing the Abel transform method is developed, which possesses the exactness of the Abel transform and the flexibility of incorporating various filters in the reconstruction process. The Abel transform is an exact method and the simplest among these commonly used methods. It is evinced in this paper that all the exact reconstruction methods for axisymmetric distributions must be equivalent to the Abel transform because of its uniqueness and exactness. Detailed proof is presented to show that the two dimensional Fourier methods when applied to axisymmetric cases is identical to the Abel transform. Discrepancies among various reconstruction method stem from the different approximations made to perform numerical calculations. An equation relating the spectrum of a set of projection date to that of the corresponding spatial distribution is obtained, which shows that the spectrum of the projection is equal to the Abel transform of the spectrum of the corresponding spatial distribution. From the equation, if either the projection or the distribution is bandwidth limited, the other is also bandwidth limited, and both have the same bandwidth. If the two are not bandwidth limited, the Abel transform has a bias against low wave number components in most practical cases. This explains why the Abel transform and all exact deconvolution methods are sensitive to high wave number noises. The filtered Abel transform is based on the fact that the Abel transform of filtered projection data is equal to an integral transform of the original projection data with the kernel function being the Abel transform of the filtering function. The kernel function is independent of the projection data and can be obtained separately when the filtering function is selected. Users can select the best filtering function for a particular set of experimental data. When the kernal function is obtained, it can be used repeatedly to a number of projection data sets (rovs) from the same experiment. When an entire flame image that contains a large number of projection lines needs to be processed, the new approach significantly reduces computational effort in comparison with the conventional approach in which each projection data set is deconvoluted separately. Computer codes have been developed to perform the filter Abel transform for an entire flame field. Measured soot volume fraction data of a jet diffusion flame are processed as an example.

Reconstructing the metric of the local Universe from number counts observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vallejo, Sergio Andres; Romano, Antonio Enea, E-mail: antonio.enea.romano@cern.ch

Number counts observations available with new surveys such as the Euclid mission will be an important source of information about the metric of the Universe. We compute the low red-shift expansion for the energy density and the density contrast using an exact spherically symmetric solution in presence of a cosmological constant. At low red-shift the expansion is more precise than linear perturbation theory prediction. We then use the local expansion to reconstruct the metric from the monopole of the density contrast. We test the inversion method using numerical calculations and find a good agreement within the regime of validity ofmore » the red-shift expansion. The method could be applied to observational data to reconstruct the metric of the local Universe with a level of precision higher than the one achievable using perturbation theory.« less

Constant-roll (quasi-)linear inflation

NASA Astrophysics Data System (ADS)

Karam, A.; Marzola, L.; Pappas, T.; Racioppi, A.; Tamvakis, K.

2018-05-01

In constant-roll inflation, the scalar field that drives the accelerated expansion of the Universe is rolling down its potential at a constant rate. Within this framework, we highlight the relations between the Hubble slow-roll parameters and the potential ones, studying in detail the case of a single-field Coleman-Weinberg model characterised by a non-minimal coupling of the inflaton to gravity. With respect to the exact constant-roll predictions, we find that assuming an approximate slow-roll behaviour yields a difference of Δ r = 0.001 in the tensor-to-scalar ratio prediction. Such a discrepancy is in principle testable by future satellite missions. As for the scalar spectral index ns, we find that the existing 2-σ bound constrains the value of the non-minimal coupling to ξphi ~ 0.29–0.31 in the model under consideration.

Hubble 2007: Science Year in Review

NASA Technical Reports Server (NTRS)

2008-01-01

This book epitomizes Hubbles continuing years of glorious accomplishments, presenting a sample of the activities, operations and observations, and scientific findings from 2007. Here is our observatory. Here are a few of our talented people. Here is what we have done. NASA plans a final servicing mission to Hubble in 2008. Two powerful new instruments are to be installed, and repairs made. After the astronauts do their wonderful work, Hubble will be more capable than at any time since launch. The science community eagerly anticipates the new opportunities for research offered by a refurbished observatory. While we do not know exactly what new science stories will appear in future editions of this book, we are certain that the frontiers of science will continue to be pushed outward by the forces of human curiosity and cleverness, channeled by the Hubble Space Telescope.

Advanced Plant Habitat Flight Unit #1

NASA Image and Video Library

2017-07-24

Inside a laboratory in the Space Station Processing Facility at NASA's Kennedy Space Center in Florida, LED plant growth lights are being checked out on the hardware for the Advanced Plant Habitat flight unit. The flight unit is an exact replica of the APH that was delivered to the International Space Station. Validation tests and post-delivery checkout was performed to prepare for space station in-orbit APH activities. The flight unit will be moved to the International Space Station Environmental Simulator to begin an experiment verification test for the science that will fly on the first mission, PH-01. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the space station.

Mars Pathfinder and the exploration of southern Amazonis Planitia

NASA Technical Reports Server (NTRS)

Barlow, Nadine G.

1994-01-01

The southern region of Amazonis Planitia provides a variety of target terrains for a roving vehicle such as the Mars Pathfinder Mission. A landing site is proposed at 4 deg N latitude 162 deg W longitude. This area has a reference altitude of between 0 and -1 km and consists of relatively smooth Amazonian-aged deposits within the entire 100 x 200 km landing ellipse. The proposed landing site is within the Upper Member Medusae Fossae Formation deposits (Amu) and near the boundary with Middle Member Medusae Fossae Formation deposits (Amm) and Member 1 Arcadia Formation plains (Aa(sub 1)). Slightly further afield are 107-km-diameter Nicholson crater, its ejecta deposits, and knobby terrain of proposed Hesperian age (HNu). Depending on the exact landing site of the spacecraft and the traverse distance of the rover, these materials also may be sampled.

Rock Moved by Mars Lander Arm, Stereo View

NASA Technical Reports Server (NTRS)

2008-01-01

The robotic arm on NASA's Phoenix Mars Lander slid a rock out of the way during the mission's 117th Martian day (Sept. 22, 2008) to gain access to soil that had been underneath the rock.The lander's Surface Stereo Imager took the two images for this stereo view later the same day, showing the rock, called 'Headless,' after the arm pushed it about 40 centimeters (16 inches) from its previous location.

'The rock ended up exactly where we intended it to,' said Matt Robinson of NASA's Jet Propulsion Laboratory, robotic arm flight software lead for the Phoenix team.

The arm had enlarged the trench near Headless two days earlier in preparation for sliding the rock into the trench. The trench was dug to about 3 centimeters (1.2 inches) deep. The ground surface between the rock's prior position and the lip of the trench had a slope of about 3 degrees downward toward the trench. Headless is about the size and shape of a VHS videotape.

The Phoenix science team sought to move the rock in order to study the soil and the depth to subsurface ice underneath where the rock had been.

This left-eye and right-eye images for this stereo view were taken at about 12:30 p.m., local solar time on Mars. The scene appears three-dimensional when seen through blue-red glasses.The view is to the north northeast of the lander.

The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by JPL, Pasadena, Calif. Spacecraft development was by Lockheed Martin Space Systems, Denver.

Evolution of DOI Usage and Registration

NASA Astrophysics Data System (ADS)

James, N.; Wanchoo, L.

2017-12-01

NASA's Earth Science Data and Information System (ESDIS) Project has implemented an automated system for assigning Digital Object Identifiers (DOIs) to Earth Science data products being managed by its network of 12 distributed active archive centers (DAACs). Using the ESDIS DOI system, over 3000 DOIs have been assigned, registered, and made publicly accessible while over 1000 assigned DOIs are being held in reserve until ready for public use. The goal is to assign a DOI to each of the 8000+ data collections under ESDIS management. DOIs make it easier for researchers to discover and use earth science data and they enable users to provide valid citations for the data they use in research. Also for the researcher wishing to reproduce the results presented in science publications, the DOI can be used to locate the exact data or data products being cited. ESDIS DOIs also provide data "Provenance" which is information about the creation and history of the data in question. This would include when the data was collected, which instrument was used to collect the data, and the version of the product at the time the DOI was assigned. Over the past few years, requests for DOIs have increased significantly as DAACs assign DOIs to both legacy data from earlier missions and new data products from in-orbit missions. This study will evaluate the evolution of DOI registration and its usage over those years comparing data products as they are organized by mission, science discipline and data product level. It is hoped that the study results will help NASA determine how to prioritize future products for DOI assignment and inform future studies that would identify trends over time of increased use of data citations resulting in increased discovery and distribution of NASA Earth science data products.

The Earth Observing System Terra Mission

NASA Technical Reports Server (NTRS)

Kaufman, Yoram J.; Einaudi, Franco (Technical Monitor)

2000-01-01

Langley's remarkable solar and lunar spectra collected from Mt. Whitney inspired Arrhenius to develop the first quantitative climate model in 1896. After the launch in Dec. 16 1999, NASA's Earth Observing AM Satellite (EOS-Terra) will repeat Langley's experiment, but for the entire planet, thus pioneering a wide array of calibrated spectral observations from space of the Earth System. Conceived in response to real environmental problems, EOS-Terra, in conjunction with other international satellite efforts, will fill a major gap in current efforts by providing quantitative global data sets with a resolution better than 1 km on the physical, chemical and biological elements of the earth system. Thus, like Langley's data, EOS-Terra can revolutionize climate research by inspiring a new generation of climate system models and enable us to assess the human impact on the environment. In the talk I shall review the historical perspective of the Terra mission and the key new elements of the mission. We expect to have first images that demonstrate the most innovative capability from EOS Terra 5 instruments: MODIS - 1.37 micron cirrus cloud channel; 250m daily coverage for clouds and vegetation change; 7 solar channels for land and aerosol studies; new fire channels; Chlorophyll fluorescence; MISR - first 9 multi angle views of clouds and vegetation; MOPITT - first global CO maps and C114 maps; ASTER - Thermal channels for geological studies with 15-90 m resolution.

The Earth Observing System Terra Mission

NASA Technical Reports Server (NTRS)

Kaufman, Yoram J.

2000-01-01

Langley's remarkable solar and lunar spectra collected from Mt. Whitney inspired Arrhenius to develop the first quantitative climate model in 1896. After the launch in Dec. 16 1999, NASA's Earth Observing AM Satellite (EOS-Terra) will repeat Langley's experiment, but for the entire planet, thus pioneering a wide array of calibrated spectral observations from space of the Earth System. Conceived in response to real environmental problems, EOS-Terra, in conjunction with other international satellite efforts, will fill a major gap in current efforts by providing quantitative global data sets with a resolution smaller than 1 km on the physical, chemical and biological elements of the earth system. Thus, like Langley's data, EOS-Terra can revolutionize climate research by inspiring a new generation of climate system models and enable us to assess the human impact on the environment. In the talk I shall review the historical perspective of the Terra mission and the key new elements of the mission. We expect to have some first images that demonstrate the most innovative capability from EOS Terra: MODIS - 1.37 microns cirrus channel; 250 m daily cover for clouds and vegetation change; 7 solar channels for land and aerosol; new fire channels; Chlorophyll fluorescence; MISR - 9 multi angle views of clouds and vegetation; MOPITT - Global CO maps and CH4 maps; ASTER - Thermal channels for geological studies with 15-90 m resolution.

Distinct EUV minimum of the solar irradiance (16-40 nm) observed by SolACES spectrometers onboard the International Space Station (ISS) in August/September 2009

NASA Astrophysics Data System (ADS)

Nikutowski, B.; Brunner, R.; Erhardt, Ch.; Knecht, St.; Schmidtke, G.

2011-09-01

In the field of terrestrial climatology the continuous monitoring of the solar irradiance with highest possible accuracy is an important goal. SolACES as a part of the ESA mission SOLAR on the ISS is measuring the short-wavelength solar EUV irradiance from 16-150 nm. This data will be made available to the scientific community to investigate the impact of the solar irradiance variability on the Earth's climate as well as the thermospheric/ionospheric interactions that are pursued in the TIGER program. Since the successful launch with the shuttle mission STS-122 on February 7th, 2008, SolACES initially recorded the low EUV irradiance during the extended solar activity minimum. Thereafter it has been observing the EUV irradiance during the increasing solar activity with enhanced intensity and changing spectral composition. SolACES consists of three grazing incidence planar grating spectrometers. In addition there are two three-signal ionisation chambers, each with exchangeable band-pass filters to determine the absolute EUV fluxes repeatedly during the mission. One important problem of space-borne instrumentation recording the solar EUV irradiance is the degradation of the spectrometer sensitivity. The two double ionisation chambers of SolACES, which could be re-filled with three different gases for each recording, allow the recalibration of the efficiencies of the three SolACES spectrometers from time to time.

Dual Ion Spectrometers and Their Calibration for the Fast Plasma Investigation on NASA's Magnetospheric Multiscale Mission

NASA Technical Reports Server (NTRS)

Coffey, V. N.; Chandler, M. O.

2017-01-01

The scientific target of NASA's Magnetospheric Multiscale (MMS) mission is to study the fundamentally important phenomenon of magnetic reconnection. Theoretical models of this process predict a small size, on the order of hundred kilometers, for the ion diffusion region where ions are demagnetized at the dayside magnetopause. This region may typically sweep over the spacecraft at relatively high speeds of 50 km/s, requiring the fast plasma investigation (FPI) instrument suite to have an extremely high time resolution for measurements of the 3D particle distribution functions. As part of the FPI on MMS, the 16 dual ion spectrometers (DIS) will provide fast (150 ms) 3D ion velocity distributions, from 10 to 30,000 eV/q, by combining the measurements from four dual spectrometers on each of four MMS spacecraft. For any multispacecraft mission, the response uniformity among the spectrometer set assumes an enhanced importance. Due to these demanding instrument requirements and the effort of calibrating more than 32 sensors (16 × 2) within a tight schedule, a highly systematic and precise calibration was required for measurement repeatability. To illustrate how this challenge was met, a brief overview of the FPI DIS was presented with a detailed discussion of the calibration method of approach and implementation. Finally, a discussion of DIS performance results, their unit-to-unit variation, and the lessons learned from this calibration effort are presented.

Heart Rate Response During Mission-Critical Tasks After Space Flight

NASA Technical Reports Server (NTRS)

Arzeno, Natalia M.; Lee, S. M. C.; Stenger, M. B.; Lawrence, E. L.; Platts, S. H.; Bloomberg, J. J.

2010-01-01

Adaptation to microgravity could impair crewmembers? ability to perform required tasks upon entry into a gravity environment, such as return to Earth, or during extraterrestrial exploration. Historically, data have been collected in a controlled testing environment, but it is unclear whether these physiologic measures result in changes in functional performance. NASA?s Functional Task Test (FTT) aims to investigate whether adaptation to microgravity increases physiologic stress and impairs performance during mission-critical tasks. PURPOSE: To determine whether the well-accepted postflight tachycardia observed during standard laboratory tests also would be observed during simulations of mission-critical tasks during and after recovery from short-duration spaceflight. METHODS: Five astronauts participated in the FTT 30 days before launch, on landing day, and 1, 6, and 30 days after landing. Mean heart rate (HR) was measured during 5 simulations of mission-critical tasks: rising from (1) a chair or (2) recumbent seated position followed by walking through an obstacle course (egress from a space vehicle), (3) translating graduated masses from one location to another (geological sample collection), (4) walking on a treadmill at 6.4 km/h (ambulation on planetary surface), and (5) climbing 40 steps on a passive treadmill ladder (ingress to lander). For tasks 1, 2, 3, and 5, astronauts were encouraged to complete the task as quickly as possible. Time to complete tasks and mean HR during each task were analyzed using repeated measures ANOVA and ANCOVA respectively, in which task duration was a covariate. RESULTS: Landing day HR was higher (P < 0.05) than preflight during the upright seat egress (7%+/-3), treadmill walk (13%+/-3) and ladder climb (10%+/-4), and HR remained elevated during the treadmill walk 1 day after landing. During tasks in which HR was not elevated on landing day, task duration was significantly greater on landing day (recumbent seat egress: 25%+/-14 and mass translation: 26%+/-12; P < 0.05). CONCLUSION: Elevated HR and increased task duration during postflight simulations of mission-critical tasks is suggestive of spaceflight-induced deconditioning. Following short-duration microgravity missions (< 16 d), work performance may be transiently impaired, but recovery is rapid.

Solar Sails

NASA Technical Reports Server (NTRS)

Young, Roy

2006-01-01

The Solar Sail Propulsion investment area has been one of the three highest priorities within the In-Space Propulsion Technology (ISPT) Project. In the fall of 2003, the NASA Headquarters' Science Mission Directorate provided funding and direction to mature the technology as far as possible through ground research and development from TRL 3 to 6 in three years. A group of experts from government, industry, and academia convened in Huntsville, Alabama to define technology gaps between what was needed for science missions to the inner solar system and the current state of the art in ultra1ightweight materials and gossamer structure design. This activity set the roadmap for development. The centerpiece of the development would be the ground demonstration of scalable solar sail systems including masts, sails, deployment mechanisms, and attitude control hardware and software. In addition, new materials would be subjected to anticipated space environments to quantify effects and assure mission life. Also, because solar sails are huge structures, and it is not feasible to validate the technology by ground test at full scale, a multi-discipline effort was established to develop highly reliable analytical models to serve as mission assurance evidence in future flight program decision-making. Two separate contractor teams were chosen to develop the SSP System Ground Demonstrator (SGD). After a three month conceptual mission/system design phase, the teams developed a ten meter diameter pathfinder set of hardware and subjected it to thermal vacuum tests to compare analytically predicted structural behavior with measured characteristics. This process developed manufacturing and handling techniques and refined the basic design. In 2005, both contractor teams delivered 20 meter, four quadrant sail systems to the largest thermal vacuum chamber in the world in Plum Brook, Ohio, and repeated the tests. Also demonstrated was the deployment and articulation of attitude control mechanisms. In conjunction with these tests, the stowed sails were subjected to launch vibration and ascent vent tests. Other investments studied radiation effects on the solar sail materials, investigated spacecraft charging issues, developed shape measuring techniques and instruments, produced advanced trajectory modeling capabilities, and identified and resolved gossamer structure dynamics issues. Technology validation flight and application to a He1iophysics science mission is on the horizon.

Autonomous Science Analysis with the New Millennium Program-Autonomous Sciencecraft Experiment

NASA Astrophysics Data System (ADS)

Doggett, T.; Davies, A. G.; Castano, R. A.; Baker, V. R.; Dohm, J. M.; Greeley, R.; Williams, K. K.; Chien, S.; Sherwood, R.

2002-12-01

The NASA New Millennium Program (NMP) is a testbed for new, high-risk technologies, including new software and hardware. The Autonomous Sciencecraft Experiment (ASE) will fly on the Air Force Research Laboratory TechSat-21 mission in 2006 is such a NMP mission, and is managed by the Jet Propulsion Laboratory, California Institute of Technology. TechSat-21 consists of three satellites, each equipped with X-band Synthetic Aperture Radar (SAR) that will occupy a 13-day repeat track Earth orbit. The main science objectives of ASE are to demonstrate that process-related change detection and feature identification can be conducted autonomously during space flight, leading to autonomous onboard retargeting of the spacecraft. This mission will observe transient geological and environmental processes using SAR. Examples of geologic processes that may be observed and investigated include active volcanism, the movement of sand dunes and transient features in desert environments, water flooding, and the formation and break-up of lake ice. Science software onboard the spacecraft will allow autonomous processing and formation of SAR images and extraction of scientific information. The subsequent analyses, performed on images formed onboard from the SAR data, will include feature identification using scalable feature "templates" for each target, change detection through comparison of current and archived images, and science discovery, a search for other features of interest in each image. This approach results in obtaining the same science return for a reduced amount of resource use (such as downlink) when compared to that from a mission operating without ASE technology. Redundant data is discarded. The science-driven goals of ASE will evolve during the ASE mission through onboard replanning software that can re-task satellite operations. If necessary, as a result of a discovery made autonomously by onboard science processing, existing observation sequences will be pre-empted to obtain data of potential high scientific content. Flight validation of this software will enable radically different missions with significant onboard decision-making and novel science concepts (onboard decision making and selective data return). This work has been carried out at the Jet Propulsion Laboratory-California Institute of Technology, under contract to NASA.

SweepSAR Sensor Technology for Dense Spatial and Temporal Coverage of Earth Change

NASA Astrophysics Data System (ADS)

Rosen, P. A.

2016-12-01

Since the 2007 National Academy of Science "Decadal Survey" report, NASA has been studying concepts for a Synthetic Aperture Radar (SAR) mission to determine Earth change in three disciplines - ecosystems, solid earth, and cryospheric sciences. NASA has joined forces with the Indian Space Research Organisation (ISRO) to fulfill these objectives. The NASA-ISRO SAR (NISAR) mission is now in development for a launch in 2021. The mission's primary science objectives are codified in a set of science requirements to study Earth land and ice deformation, and ecosystems, globally with 12-day sampling over all land and ice-covered surfaces throughout the mission life. The US and Indian science teams share global science objectives; in addition, India has developed a set of local objectives in agricultural biomass estimation, Himalayan glacier characterization, and coastal ocean measurements in and around India. Both the US and India have identified agricultural and infrastructure monitoring, and disaster response as high priority applications for the mission. With this range of science and applications objectives, NISAR has demanding coverage, sampling, and accuracy requirements. The system requires a swath of over 240 km at 3-10 m SAR imaging resolution, using full polarimetry where needed. Given the broad range of phenomena and wide range of sensitivities needed, NISAR carries two radars, one operating at L-band (24 cm wavelength) and the other at S-band (10 cm wavelength). The system uses a new "scan-on-receive" ("SweepSAR") technology at both L-band and S-band, that enables full swath coverage without loss of resolution or polarimetric diversity. Both radars can operate simultaneously. The L-band system is being designed to operate up to 50 minutes per orbit, and the S-band system up to 10 minutes per orbit. The orbit will be controlled to within 300 m for repeat-pass interferometry measurements. This unprecedented coverage in space, time, polarimetry, and frequency, will add a new and rich data set to the international constellation of sensors studying Earth surface change. In this talk, we will describe the mission's expected contributions to geodetic imaging in support of time-series analysis of dynamic changes of Earth's surface.

Small Spacecraft Constellation Concept for Mars Atmospheric Radio Occultations

NASA Astrophysics Data System (ADS)

Asmar, S. W.; Mannucci, A. J.; Ao, C. O.; Kobayashi, M. M.; Lazio, J.; Marinan, A.; Massone, G.; McCandless, S. E.; Preston, R. A.; Seubert, J.; Williamson, W.

2017-12-01

First demonstrated in 1965 when Mariner IV flew by Mars and determined the salient features of its atmosphere, radio occultation experiments have been carried out on numerous planetary missions with great discoveries. These experiments utilize the now classic configuration of a signal from a single planetary spacecraft to Earth receiving stations, where the science data are acquired. The Earth science community advanced the technique to utilizing a constellation of spacecraft with the radio occultation links between the spacecraft, enabled by the infrastructure of the Global Positioning System. With the advent of small and less costly spacecraft, such as planetary CubeSats and other variations, such as the anticipated innovative Mars Cube One mission, crosslinks among small spacecraft can be used to study other planets in the near future. Advantages of this type of experiment include significantly greater geographical coverage, which could reach global coverage over a few weeks with a small number of spacecraft. Repeatability of the global coverage can lead to examining temperature-pressure profiles and ionospheric electron density profiles, on daily, seasonal, annual, or other time scales of interest. The higher signal-to-noise ratio for inter-satellite links, compared to a link to Earth, decreases the design demands on the instrumentation (smaller antennas and transmitters, etc.). After an actual Mars crosslink demonstration, this concept has been in development using Mars as a possible target. Scientific objectives, delivery methods, operational scenarios and end-to-end configuration have been documented. Science objectives include determining the state and variability of the lower Martian atmosphere, which has been an identified as a high priority objective by the Mars Exploration Program Analysis Group, particularly as it relates to entry, descent, and landing and ascent for future crewed and robotic missions. This paper will present the latest research on the proposed mission concept including the possible spatial and temporal coverage, resolution of observables, mission design and expected results.

The High Energy Transient Explorer (HETE): Mission and Science Overview

NASA Astrophysics Data System (ADS)

Ricker, G. R.; Atteia, J.-L.; Crew, G. B.; Doty, J. P.; Fenimore, E. E.; Galassi, M.; Graziani, C.; Hurley, K.; Jernigan, J. G.; Kawai, N.; Lamb, D. Q.; Matsuoka, M.; Pizzichini, G.; Shirasaki, Y.; Tamagawa, T.; Vanderspek, R.; Vedrenne, G.; Villasenor, J.; Woosley, S. E.; Yoshida, A.

2003-04-01

The High Energy Transient Explorer (HETE ) mission is devoted to the study of gamma-ray bursts (GRBs) using soft X-ray, medium X-ray, and gamma-ray instruments mounted on a compact spacecraft. The HETE satellite was launched into equatorial orbit on 9 October 2000. A science team from France, Japan, Brazil, India, Italy, and the US is responsible for the HETE mission, which was completed for ~ 1/3 the cost of a NASA Small Explorer (SMEX). The HETE mission is unique in that it is entirely ``self-contained,'' insofar as it relies upon dedicated tracking, data acquisition, mission operations, and data analysis facilities run by members of its international Science Team. A powerful feature of HETE is its potential for localizing GRBs within seconds of the trigger with good precision (~ 10') using medium energy X-rays and, for a subset of bright GRBs, improving the localization to ~ 30''accuracy using low energy X-rays. Real-time GRB localizations are transmitted to ground observers within seconds via a dedicated network of 14 automated ``Burst Alert Stations,'' thereby allowing prompt optical, IR, and radio follow-up, leading to the identification of counterparts for a large fraction of HETE -localized GRBs. HETE is the only satellite that can provide near-real time localizations of GRBs, and that can localize GRBs that do not have X-ray, optical, and radio afterglows, during the next two years. These capabilities are the key to allowing HETE to probe further the unique physics that produces the brightest known photon sources in the universe. To date (December 2002), HETE has produced 31 GRB localizations. Localization accuracies are routinely in the 4'- 20' range; for the five GRBs with SXC localization, accuracies are ~1-2'. In addition, HETE has detected ~ 25 bursts from soft gamma repeaters (SGRs), and >600 X-ray bursts (XRBs).

Human factors for the Moon: the gap in anthropometric data.

NASA Astrophysics Data System (ADS)

Lia Schlacht, Irene; Foing, Bernard H.; Rittweger, Joern; Masali, Melchiorre; Stevenin, Hervé

2016-07-01

Since the space era began, we learned first to survive and then to live in space. In the state of the art, we know how important human factors research and development is to guarantee maximum safety and performance for human missions. With the extension of the duration of space missions, we also need to learn how habitability and comfort factors are closely related to safety and performance. Humanities disciplines such as design, architecture, anthropometry, and anthropology are now involved in mission design from the start. Actual plans for building a simulated Moon village in order to simulate and test Moon missions are now being carried out using a holistic approach, involving multidisciplinary experts cooperating concurrently with regard to the interactions among humans, technology, and the environment. However, in order to implement such plans, we need basic anthropometrical data, which is still missing. In other words: to optimize performance, we need to create doors and ceilings with dimensions that support a natural human movement in the reduced gravity environment of the Moon, but we are lacking detailed anthropometrical data on human movement on the Moon. In the Apollo missions more than 50 years ago, no anthropometrical studies were carried in hypogravity out as far as we know. The necessity to collect data is very consistent with state-of-the-art research. We still have little knowledge of how people will interact with the Moon environment. Specifically, it is not known exactly which posture, which kind of walking and running motions astronauts will use both inside and outside a Moon station. Considering recent plans for a Moon mission where humans will spend extensive time in reduced gravity conditions, the need for anthropometric, biomechanics and kinematics field data is a priority in order to be able to design the right architecture, infrastructure, and interfaces. Objective of this paper: Bring knowledge on the relevance of anthropometrical and human factors contribution Present the ongoing research on this field Share innovative methodologies in order to acquire feedback from other specialist. This research is aimed at reconsidering the methodologies from the viewpoint of anthropometry and human system interaction in a different kind of gravity and carry out new investigations that may help to prepare for the next Moon mission, but which can also be used for advanced applications on Earth. Experimental setups and methodologies for achieving anthropometrical data will be described. In particular, combined studies involving bed rest, treadmills, parabolic flight, neutral buoyancy, and weight suspension with cables will be presented. From a spin-off perspective, this research is also extremely promising in terms of basic research aimed at better understanding human physiological mechanisms ruling equilibrium, deambulation, and related topics, which are also useful for applications on Earth.

Results of scatterometer systems analysis for NASA/MSC Earth Observation Sensor Evaluation Program.

NASA Technical Reports Server (NTRS)

Krishen, K.; Vlahos, N.; Brandt, O.; Graybeal, G.

1971-01-01

Radar scatterometers have applications in the NASA/MSC Earth Observation Aircraft Program. Over a period of several years, several missions have been flown over both land and ocean. In this paper a system evaluation of the NASA/MSC 13.3-GHz Scatterometer System is presented. The effects of phase error between the Scatterometer channels, antenna pattern deviations, aircraft attitude deviations, environmental changes, and other related factors such as processing errors, system repeatability, and propeller modulation, were established. Furthermore, the reduction in system errors and calibration improvement was investigated by taking into account these parameter deviations. Typical scatterometer data samples are presented.

A Feasability Study of the Wheel Electrostatic Spectrometer

NASA Technical Reports Server (NTRS)

Johansen, Michael Ryan; Phillips, James Ralph; Kelley, Joshua David; Mackey, Paul J.; Holbert, Eirik; Clements, Gregory R.; Calle, Carlos I.

2014-01-01

Mars rover missions rely on time-consuming, power-exhausting processes to analyze the Martian regolith. A low power electrostatic sensor in the wheels of a future Mars rover could be used to quickly determine when the rover is driving over a different type of regolith. The Electrostatics and Surface Physics Laboratory at NASA's Kennedy Space Center developed the Wheel Electrostatic Spectrometer as a feasibility study to investigate this option. In this paper, we discuss recent advances in this technology to increase the repeatability of the tribocharging experiments, along with supporting data. In addition, we discuss the development of a static elimination tool optimized for Martian conditions.

Geosynchronous SAR for Terrain & Atmosphere with short Revisit (GeoSTARe)

NASA Astrophysics Data System (ADS)

Monti-Guarnieri, Andrea; Recchia, Andrea; Rocca, Fabio; Bombaci, Ornella; Germani, Chiara; Broquetas, Antoni; Wadge, Geoff; Hobbs, Steve

2016-08-01

GeoSTARe would be a mission combining the continuous view capabilities from geostationary orbits of super-continental areas with the all-day, all-weather imaging capabilities of Synthetic Aperture Radar. It would complement Copernicus Sentinel-1 bringing the repeat time from days down to hours.In that, it would provide novel and unique observations. The well proven potentials of Radar in sensing roughness, deformations, and moisture, combined with the short time to get any image, from minutes to an hour, and the immediate data download and exploitation (thanks to the geostationary orbit) makes GeoSTARe a game changer in those fields where hourly-to-daily monitoring is a must.

Recent and episodic volcanic and glacial activity on Mars revealed by the High Resolution Stereo Camera.

PubMed

Neukum, G; Jaumann, R; Hoffmann, H; Hauber, E; Head, J W; Basilevsky, A T; Ivanov, B A; Werner, S C; van Gasselt, S; Murray, J B; McCord, T

2004-12-23

The large-area coverage at a resolution of 10-20 metres per pixel in colour and three dimensions with the High Resolution Stereo Camera Experiment on the European Space Agency Mars Express Mission has made it possible to study the time-stratigraphic relationships of volcanic and glacial structures in unprecedented detail and give insight into the geological evolution of Mars. Here we show that calderas on five major volcanoes on Mars have undergone repeated activation and resurfacing during the last 20 per cent of martian history, with phases of activity as young as two million years, suggesting that the volcanoes are potentially still active today. Glacial deposits at the base of the Olympus Mons escarpment show evidence for repeated phases of activity as recently as about four million years ago. Morphological evidence is found that snow and ice deposition on the Olympus construct at elevations of more than 7,000 metres led to episodes of glacial activity at this height. Even now, water ice protected by an insulating layer of dust may be present at high altitudes on Olympus Mons.

Normal pregnancy is associated with an increase in thrombin generation from the very early stages of the first trimester.

PubMed

Bagot, C N; Leishman, E; Onyiaodike, C C; Jordan, F; Freeman, D J

2017-09-01

Pregnancy is a hypercoagulable state associated with an increased risk of venous thrombosis, which begins during the first trimester, but the exact time of onset is unknown. Thrombin generation, a laboratory marker of thrombosis risk, increases during normal pregnancy but it is unclear exactly how early this increase occurs. We assessed thrombin generation by Calibrated Automated Thrombography in women undergoing natural cycle in vitro fertilization, who subsequently gave birth at term following a normal pregnancy (n=22). Blood samples were taken just prior to conception and repeated five times during very early pregnancy, up to Day 59 estimated gestation. Mean Endogenous Thrombin Potential (ETP), peak thrombin generation and Velocity Index (VI) increased significantly from pre-pregnancy to Day 43 gestation (p=0.024-0.0004). This change persisted to Day 59 gestation. The mean of the percentage change from baseline, accounting for inter-individual variation, in ETP, peak thrombin and VI increased significantly from pre-pregnancy to Day 32 gestation (p=0.0351-<0.0001) with the mean increase from baseline persisting to Day 59 gestation. Thrombin generation increases significantly during the very early stages of normal pregnancy when compared to the pre-pregnancy state. The increased risk of venous thrombosis therefore likely begins very early in a woman's pregnancy, suggesting that women considered clinically to be at high thrombotic risk should start thromboprophylaxis as early as possible after a positive pregnancy test. Copyright © 2017 Elsevier Ltd. All rights reserved.

Shaded Relief with Height as Color, Kerguelen Island, south Indian Ocean

NASA Technical Reports Server (NTRS)

2002-01-01

These two images show exactly the same area, Kerguelen Island in the southern Indian Ocean. The image on the left was created using the best global topographic data set previously available, the U.S. Geological Survey's GTOPO30. In contrast, the much more detailed image on the right was generated with data from the Shuttle Radar Topography Mission, which collected enough measurements to map 80 percent of Earth's landmass at this level of precision.

Discovered in 1772 by French navigator Chevalier Yves deKerguelen-Tremarac, Kerguelen is the largest of a group of 300 islands, islets and reefs that make up the Kerguelen Archipelago. The islands lie atop the Kerguelen-Gaussberg Ridge and are built up of a thick series of lava flows with deposits of fragmented volcanic rock and some granite. Ice covers about one-third of the island, with the large Cook Glacier visible as the tan-colored region at the center-left. The highest point at 1,850 meters (6,068 feet) is glacier-covered Mount Ross, located near the bottom center. The coastline of the main island is highly irregular with a large number of peninsulas linked to the island by narrow isthmuses. Remarkably, although the island is 120 by 140 kilometers (75 by 87 miles) in size no point is more than 20 kilometers (12 miles) from the sea.

For some parts of the globe, Shuttle Radar Topography Mission measurements are 30 times more precise than previously available topographical information, according to NASA scientists. Mission data will be a welcome resource for national and local governments, scientists, commercial enterprises, and members of the public alike. The applications are as diverse as earthquake and volcano studies, flood control, transportation, urban and regional planning, aviation, recreation, and communications. The data's military applications include mission planning and rehearsal, modeling, and simulation.

Elevation data used in this image was acquired by the Shuttle Radar Topography Mission aboard Space Shuttle Endeavour, launched on Feb. 11,2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR)that flew twice on Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect 3-D measurements of Earth's surface. To collect the 3-D data, engineers added a 60-meter approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense, and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, Calif., for NASA's Earth Science Enterprise, Washington, D.C.

Size: 222 kilometers by 146 kilometers (138 miles by 91 miles) Location: 49.1 degrees South latitude, 69.5 degrees East longitude Orientation: North is at the top Date Acquired: February 2000 (SRTM)

Effects of Orbit and Pointing Geometry of a Spaceborne Formation for Monostatic-Bistatic Radargrammetry on Terrain Elevation Measurement Accuracy

PubMed Central

Renga, Alfredo; Moccia, Antonio

2009-01-01

During the last decade a methodology for the reconstruction of surface relief by Synthetic Aperture Radar (SAR) measurements – SAR interferometry – has become a standard. Different techniques developed before, such as stereo-radargrammetry, have been experienced from space only in very limiting geometries and time series, and, hence, branded as less accurate. However, novel formation flying configurations achievable by modern spacecraft allow fulfillment of SAR missions able to produce pairs of monostatic-bistatic images gathered simultaneously, with programmed looking angles. Hence it is possible to achieve large antenna separations, adequate for exploiting to the utmost the stereoscopic effect, and to make negligible time decorrelation, a strong liming factor for repeat-pass stereo-radargrammetric techniques. This paper reports on design of a monostatic-bistatic mission, in terms of orbit and pointing geometry, and taking into account present generation SAR and technology for accurate relative navigation. Performances of different methods for monostatic-bistatic stereo-radargrammetry are then evaluated, showing the possibility to determine the local surface relief with a metric accuracy over a wide range of Earth latitudes. PMID:22389594

Using a Smartphone Camera for Nanosatellite Attitude Determination

NASA Astrophysics Data System (ADS)

Shimmin, R.

2014-09-01

The PhoneSat project at NASA Ames Research Center has repeatedly flown a commercial cellphone in space. As this project continues, additional utility is being extracted from the cell phone hardware to enable more complex missions. The camera in particular shows great potential as an instrument for position and attitude determination, but this requires complex image processing. This paper outlines progress towards that image processing capability. Initial tests on a small collection of sample images have demonstrated the determination of a Moon vector from an image by automatic thresholding and centroiding, allowing the calibration of existing attitude control systems. Work has been undertaken on a further set of sample images towards horizon detection using a variety of techniques including thresholding, edge detection, applying a Hough transform, and circle fitting. Ultimately it is hoped this will allow calculation of an Earth vector for attitude determination and an approximate altitude. A quick discussion of work towards using the camera as a star tracker is then presented, followed by an introduction to further applications of the camera on space missions.

Check-Up of Planet Earth at the Turn of the Millennium Anticipated New Phase in Earth Sciences

NASA Technical Reports Server (NTRS)

Kaufman, Yoram

1999-01-01

Langley's remarkable solar and lunar spectra collected from mt. Whitney inspired Arrhenius to develop the first quantitative climate model in 1896. In 1999, NASA's Earth Observing AM Satellite named recently "Terra" (by Ms. Sasha Jones, a 17 year old student in St. Louis, MO) will repeat Langley's experiment, but for the entire planet, thus pioneering calibrated spectral observations from space. Conceived in response to real environmental problems, EOS-AM, in conjunction with other international satellite efforts, will fill a major gap in current efforts by providing quantitative global data sets with a resolution of few kilometers on the physical, chemical and biological elements of the earth system. Thus, like Langley's data, EOS-AM can revolutionize climate research by inspiring a new generation of climate system models and enable us to assess the human impact on the environment. In this talk I shall a give a historical perspective for the need for this expensive mission, give examples of the science that we anticipate to achieve using Terra measurements and describe this exciting mission.

Le premier ciel de Gaia

NASA Astrophysics Data System (ADS)

Turon, Catherine; Arenou, Frederic

2016-11-01

On 14 September 2016, the first data release of the ESA's Gaia mission has been published. Based on raw data collected between 25 July 2014 and 16 Septembre 2015, i.e. only over the first 14 months of mission, this first "Gaia sky" includes the accurate positions and Gaia magnitudes of more than a billion objects: it is already the largest all-sky survey to date even though the incomplete scanning of some areas of the sky is reflected by some artefacts that will gradually fade out as more data are collected. In addition, for a subset of two million stars in common between Gaia and the Hipparcos and Tycho-2 catalogues, positions, parallaxes and proper motions have been obtained with an accuracy 3 times better than those of Hipparcos and for 20 times more stars. Finally, light curves of about 3200 RR Lyrae and Cepheid variable stars have been obtained from the repeated observations of the Ecliptic Poles made during the first month of Gaia operations. A first glance at the quality of the data is presented here, as well as some remarks about the use of this very preliminary Gaia catalogue.

Mission Design for the Lunar Reconnaissance Orbiter

NASA Technical Reports Server (NTRS)

Beckman, Mark

2007-01-01

The Lunar Reconnaissance Orbiter (LRO) will be the first mission under NASA's Vision for Space Exploration. LRO will fly in a low 50 km mean altitude lunar polar orbit. LRO will utilize a direct minimum energy lunar transfer and have a launch window of three days every two weeks. The launch window is defined by lunar orbit beta angle at times of extreme lighting conditions. This paper will define the LRO launch window and the science and engineering constraints that drive it. After lunar orbit insertion, LRO will be placed into a commissioning orbit for up to 60 days. This commissioning orbit will be a low altitude quasi-frozen orbit that minimizes stationkeeping costs during commissioning phase. LRO will use a repeating stationkeeping cycle with a pair of maneuvers every lunar sidereal period. The stationkeeping algorithm will bound LRO altitude, maintain ground station contact during maneuvers, and equally distribute periselene between northern and southern hemispheres. Orbit determination for LRO will be at the 50 m level with updated lunar gravity models. This paper will address the quasi-frozen orbit design, stationkeeping algorithms and low lunar orbit determination.

New NASA 3D Animation Shows Seven Days of Simulated Earth Weather

NASA Image and Video Library

2014-08-11

This visualization shows early test renderings of a global computational model of Earth's atmosphere based on data from NASA's Goddard Earth Observing System Model, Version 5 (GEOS-5). This particular run, called Nature Run 2, was run on a supercomputer, spanned 2 years of simulation time at 30 minute intervals, and produced Petabytes of output. The visualization spans a little more than 7 days of simulation time which is 354 time steps. The time period was chosen because a simulated category-4 typhoon developed off the coast of China. The 7 day period is repeated several times during the course of the visualization. Credit: NASA's Scientific Visualization Studio Read more or download here: svs.gsfc.nasa.gov/goto?4180 NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Sensor Data Distribution With Robustness and Reliability: Toward Distributed Components Model

NASA Technical Reports Server (NTRS)

Alena, Richard L.; Lee, Charles

2005-01-01

In planetary surface exploration mission, sensor data distribution is required in many aspects, for example, in navigation, scheduling, planning, monitoring, diagnostics, and automation of the field tasks. The challenge is to distribute such data in the robust and reliable way so that we can minimize the errors caused by miscalculations, and misjudgments that based on the error data input in the mission. The ad-hoc wireless network on planetary surface is not constantly connected because of the nature of the rough terrain and lack of permanent establishments on the surface. There are some disconnected moments that the computation nodes will re-associate with different repeaters or access points until connections are reestablished. Such a nature requires our sensor data distribution software robust and reliable with ability to tolerant disconnected moments. This paper presents a distributed components model as a framework to accomplish such tasks. The software is written in Java and utilized the available Java Message Services schema and the Boss implementation. The results of field experimentations show that the model is very effective in completing the tasks.

Mean hydrography on the continental shelf from 26 repeat glider deployments along Southeastern Australia

PubMed Central

Schaeffer, Amandine; Roughan, Moninya; Austin, Tim; Everett, Jason D.; Griffin, David; Hollings, Ben; King, Edward; Mantovanelli, Alessandra; Milburn, Stuart; Pasquer, Benedicte; Pattiaratchi, Charitha; Robertson, Robin; Stanley, Dennis; Suthers, Iain; White, Dana

2016-01-01

Since 2008, 26 glider missions have been undertaken along the continental shelf of southeastern Australia. Typically these missions have spanned the continental shelf on the inshore edge of the East Australian Current from 29.5–33.5°S. This comprehensive dataset of over 33,600 CTD profiles from the surface to within 10 m of the bottom in water depths ranging 25–200 m provides new and unprecedented high resolution observations of the properties of the continental shelf waters adjacent to a western boundary current, straddling the region where it separates from the coast. The region is both physically and biologically significant, and is also in a hotspot of ocean warming. We present gridded mean fields for temperature, salinity and density, but also dissolved oxygen and chlorophyll-a fluorescence indicative of phytoplankton biomass. This data will be invaluable for understanding shelf stratification, circulation, biophysical and bio-geochemical interactions, as well as for the validation of high-resolution ocean models or serving as teaching material. PMID:27575831

Animal imaging studies of potential brain damage

NASA Astrophysics Data System (ADS)

Gatley, S. J.; Vazquez, M. E.; Rice, O.

To date, animal studies have not been able to predict the likelihood of problems in human neurological health due to HZE particle exposure during space missions outside the Earth's magnetosphere. In ongoing studies in mice, we have demonstrated that cocaine stimulated locomotor activity is reduced by a moderate dose (120 cGy) of 1 GeV 56Fe particles. We postulate that imaging experiments in animals may provide more sensitive and earlier indicators of damage due to HZE particles than behavioral tests. Since the small size of the mouse brain is not well suited to the spatial resolution offered by microPET, we are now repeating some of our studies in a rat model. We anticipate that this will enable us to identify imaging correlates of behavioral endpoints. A specific hypothesis of our studies is that changes in the metabolic rate for glucose in striatum of animals will be correlated with alterations in locomotor activity. We will also evaluate whether the neuroprotective drug L-deprenyl reduces the effect of radiation on locomotor activity. In addition, we will conduct microPET studies of brain monoamine oxidase A and monoamine oxidase B in rats before and at various times after irradiation with HZE particles. The hypothesis is that monoamine oxidase A, which is located in nerve terminals, will be unchanged or decreased after irradiation, while monoamine oxidase B, which is located in glial cells, will be increased after irradiation. Neurochemical effects that could be measured using PET could in principle be applied in astronauts, in terms of detecting and monitoring subtle neurological damage that might have occurred during long space missions. More speculative uses of PET are in screening candidates for prolonged space missions (for example, for adequate reserve in critical brain circuits) and in optimizing medications to treat impairments after missions.

The RAVAN CubeSat Mission: A Pathfinder for a New Measurement of Earth's Radiation Budget

NASA Astrophysics Data System (ADS)

Swartz, W.; Lorentz, S. R.; Huang, P. M.; Smith, A. W.; Deglau, D.; Reynolds, E.; Carvo, J.; Papadakis, S.; Wu, D. L.; Wiscombe, W. J.; Dyrud, L. P.

2016-12-01

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat is a pathfinder for a constellation to measure the Earth's radiation imbalance (ERI), which is the single most important quantity for predicting the course of climate change over the next century. RAVAN demonstrates a small, accurate radiometer that measures top-of-the-atmosphere Earth-leaving fluxes of total and solar-reflected radiation. Coupled with knowledge of the incoming radiation from the Sun, a constellation of such measurements would aim to determine ERI directly. Our objective with RAVAN is to establish that a compact radiometer that is absolutely calibrated to climate accuracy can be built and operated in space for low cost. The radiometer, hosted on a 3U CubeSat, relies on two key technologies. The first is the use of vertically aligned carbon nanotubes (VACNTs) as the radiometer absorber. VACNT forests are some of the blackest materials known and have an extremely flat spectral response over a wide wavelength range. The second key technology is a gallium fixed-point blackbody calibration source, embedded in RAVAN's sensor head contamination cover, that serves as a stable and repeatable reference to track the long-term degradation of the sensor. Absolute calibration is also maintained by regular solar and deep space views. We present the scientific motivation for the NASA-funded mission, design and characterization of the spacecraft, and mission operations concept. Pending a successful launch in fall 2016, we will also present the first results on-orbit. RAVAN will help enable the development of an Earth radiation budget constellation mission that can provide the measurements needed for superior predictions of future climate change.

A COTS-Based Attitude Dependent Contact Scheduling System

NASA Technical Reports Server (NTRS)

DeGumbia, Jonathan D.; Stezelberger, Shane T.; Woodard, Mark

2006-01-01

The mission architecture of the Gamma-ray Large Area Space Telescope (GLAST) requires a sophisticated ground system component for scheduling the downlink of science data. Contacts between the ````````````````` satellite and the Tracking and Data Relay Satellite System (TDRSS) are restricted by the limited field-of-view of the science data downlink antenna. In addition, contacts must be scheduled when permitted by the satellite s complex and non-repeating attitude profile. Complicating the matter further, the long lead-time required to schedule TDRSS services, combined with the short duration of the downlink contact opportunities, mandates accurate GLAST orbit and attitude modeling. These circumstances require the development of a scheduling system that is capable of predictively and accurately modeling not only the orbital position of GLAST but also its attitude. This paper details the methods used in the design of a Commercial Off The Shelf (COTS)-based attitude-dependent. TDRSS contact Scheduling system that meets the unique scheduling requirements of the GLAST mission, and it suggests a COTS-based scheduling approach to support future missions. The scheduling system applies filtering and smoothing algorithms to telemetered GPS data to produce high-accuracy predictive GLAST orbit ephemerides. Next, bus pointing commands from the GLAST Science Support Center are used to model the complexities of the two dynamic science gathering attitude modes. Attitude-dependent view periods are then generated between GLAST and each of the supporting TDRSs. Numerous scheduling constraints are then applied to account for various mission specific resource limitations. Next, an optimization engine is used to produce an optimized TDRSS contact schedule request which is sent to TDRSS scheduling for confirmation. Lastly, the confirmed TDRSS contact schedule is rectified with an updated ephemeris and adjusted bus pointing commands to produce a final science downlink contact schedule.

A merged surface reflectance product from the Landsat and Sentinel-2 Missions

NASA Astrophysics Data System (ADS)

Vermote, E.; Claverie, M.; Masek, J. G.; Becker-Reshef, I.; Justice, C. O.

2013-12-01

This project is aimed at producing a merged surface product from the Landsat and Sentinel-2 missions to ultimately achieve high temporal coverage (~2 days repeat cycle) at high spatial resolution (20-60m). The goal is to achieve a seamless/consistent stream of surface reflectance data from the different sensors. The first part of this presentation discusses the basic requirements of such a product and the necessary processing steps: mainly calibration, atmospheric corrections, BRDF effect corrections, spectral band pass adjustments and gridding. We demonstrate the performance of those different corrections by using MODIS and VIIRS (Climate Modeling Grid at 0.05deg) data globally as well as Formosat-2 (8m spatial resolution) data (one crop site in South of France where 105 scenes were acquired during 2006-2010). The consistency of the surface reflectance product from MODIS and Formosat-2 ranges from 6 to 8% relative depending on the spectral bands (Green to NIR) with a bias between 2% (NIR) to 5% (green), which is acceptable given the cumulated limitation in cross-calibration, atmospheric correction and BRDF correction. The second part is devoted to the simulation of the merged Landsat and Sentinel-2 mission by using Landsat-7, LDCM (early) and SPOT-4 Take 5 dataset. SPOT-4 Take 5 dataset is a collection of 42 sites distributed globally and systematically acquired by SPOT-4 HRV every 5 days during the decommissioning phase of the SPOT4 mission (February-May 2013). Finally, the benefits of such a merged surface reflectance at high spatial and temporal resolution are discussed within the context of the agricultural monitoring, in particular in the perspective of the GEOGLAM (Global Earth Observation for Global Land Agriculture Monitoring) project.