40 CFR 63.7900 - What emissions limitations and work practice standards must I meet for containers?

Code of Federal Regulations, 2013 CFR

2013-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Containers § 63.7900 What emissions limitations and work practice standards must... your container except at the times the container is used for treatment of remediation material by a...

40 CFR 63.7900 - What emissions limitations and work practice standards must I meet for containers?

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Containers § 63.7900 What emissions limitations and work practice standards must... your container except at the times the container is used for treatment of remediation material by a...

40 CFR 63.7900 - What emissions limitations and work practice standards must I meet for containers?

Code of Federal Regulations, 2012 CFR

2012-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS... Pollutants: Site Remediation Containers § 63.7900 What emissions limitations and work practice standards must... your container except at the times the container is used for treatment of remediation material by a...

40 CFR 63.7900 - What emissions limitations and work practice standards must I meet for containers?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Pollutants: Site Remediation Containers § 63.7900 What emissions limitations and work practice standards must... your container except at the times the container is used for treatment of remediation material by a... either of the conditions in paragraphs (b)(3)(i) or (ii) apply to the remediation material placed in your...

48 CFR 17.106-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., labor learning, and other nonrecurring costs to be incurred by an “average” prime contractor or..., training, and transportation to and from the job site of a specialized work force, and unrealized labor learning. They shall not include any costs of labor or materials, or other expenses (except as indicated...

Prediction of active sites of enzymes by maximum relevance minimum redundancy (mRMR) feature selection.

PubMed

Gao, Yu-Fei; Li, Bi-Qing; Cai, Yu-Dong; Feng, Kai-Yan; Li, Zhan-Dong; Jiang, Yang

2013-01-27

Identification of catalytic residues plays a key role in understanding how enzymes work. Although numerous computational methods have been developed to predict catalytic residues and active sites, the prediction accuracy remains relatively low with high false positives. In this work, we developed a novel predictor based on the Random Forest algorithm (RF) aided by the maximum relevance minimum redundancy (mRMR) method and incremental feature selection (IFS). We incorporated features of physicochemical/biochemical properties, sequence conservation, residual disorder, secondary structure and solvent accessibility to predict active sites of enzymes and achieved an overall accuracy of 0.885687 and MCC of 0.689226 on an independent test dataset. Feature analysis showed that every category of the features except disorder contributed to the identification of active sites. It was also shown via the site-specific feature analysis that the features derived from the active site itself contributed most to the active site determination. Our prediction method may become a useful tool for identifying the active sites and the key features identified by the paper may provide valuable insights into the mechanism of catalysis.

10 CFR 26.211 - Fatigue assessments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Fatigue assessments. 26.211 Section 26.211 Energy NUCLEAR... competently perform his or her duties for any part of a working tour because of fatigue, except if, following... summary for each nuclear power plant site of instances of fatigue assessments that were conducted during...

10 CFR 26.211 - Fatigue assessments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Fatigue assessments. 26.211 Section 26.211 Energy NUCLEAR... competently perform his or her duties for any part of a working tour because of fatigue, except if, following... summary for each nuclear power plant site of instances of fatigue assessments that were conducted during...

10 CFR 26.211 - Fatigue assessments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Fatigue assessments. 26.211 Section 26.211 Energy NUCLEAR... competently perform his or her duties for any part of a working tour because of fatigue, except if, following... summary for each nuclear power plant site of instances of fatigue assessments that were conducted during...

The Recession as the Site of the Exceptional: Young People, Self-Determination and Social Mobility

ERIC Educational Resources Information Center

Luttrell-Rowland, Mikaela

2016-01-01

This paper examines the importance of "self-determination" and "hard work" found within interviews with a group of young people in Manchester, England. The author suggests that moments of apparent contradiction within the interviews have much to offer, particularly when analysed in relation to discussions of inequality and…

Real-Time Visualization of Active Species in a Single-Site Metal–Organic Framework Photocatalyst

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Sizhuo; Pattengale, Brian; Lee, Sungsik

In this work, we report a new single-site photocatalyst (Co-Ru-UIO- 67(bpy)) based on a metal-organic framework platform with incorporated molecular photosensitizer and catalyst. We show that this catalyst not only demonstrates exceptional activity for light-driven H2 production but also can be recycled without loss of activity. Using the combination of optical transient absorption spectroscopy and in situ X-ray absorption spectroscopy, we not only captured the key CoI intermediate species formed after ultrafast charge transfer from the incorporated photosensitizer but also identified the rate-limiting step in the catalytic cycle, providing insight into the catalysis mechanism of these single-site metal-organic framework photocatalysts.

When siting works, Canada-style.

PubMed

Rabe, B G

1992-01-01

Hazardous waste management poses increasing problems for Canadian provinces and American states, given the vast quantities and types of wastes generated and the virtual inability to open new storage, treatment, or disposal facilities. The Canadian experience is very similar to the American one in many respects, except for the fact that three provinces (Alberta, Manitoba, and Quebec) have devised alternative approaches to siting that appear successful in moving beyond the political gridlock so common on this issue. In each of these cases, traditional, top-down approaches to siting have been eschewed in favor of a more comprehensive approach that includes extensive public participation, economic and social compensation packages, formal partnerships between public and private organizations, and direct links between siting proposals and other aspects of waste management, including waste reduction, recycling, and export/import control.

Field Demonstrations of Five Geophysical Methods that Could Be Used to Characterize Deposits of Alluvial Aggregate

USGS Publications Warehouse

Ellefsen, K.J.; Burton, B.L.; Lucius, J.E.; Haines, S.S.; Fitterman, D.V.; Witty, J.A.; Carlson, D.; Milburn, B.; Langer, W.H.

2007-01-01

Personnel from the U.S. Geological Survey and Martin Marietta Aggregates, Inc., conducted field demonstrations of five different geophysical methods to show how these methods could be used to characterize deposits of alluvial aggregate. The methods were time-domain electromagnetic sounding, electrical resistivity profiling, S-wave reflection profiling, S-wave refraction profiling, and P-wave refraction profiling. All demonstrations were conducted at one site within a river valley in central Indiana, where the stratigraphy consisted of 1 to 2 meters of clay-rich soil, 20 to 35 meters of alluvial sand and gravel, 1 to 6 meters of clay, and multiple layers of limestone and dolomite bedrock. All geophysical methods, except time-domain electromagnetic sounding, provided information about the alluvial aggregate that was consistent with the known geology. Although time-domain electromagnetic sounding did not work well at this site, it has worked well at other sites with different geology. All of these geophysical methods complement traditional methods of geologic characterization such as drilling.

Spectroscopic investigation on assisted sonocatalytic damage of bovine serum albumin (BSA) by metronidazole (MTZ) under ultrasonic irradiation combined with nano-sized ZnO

NASA Astrophysics Data System (ADS)

Gao, Jingqun; Liu, Bin; Wang, Jun; Jin, Xudong; Jiang, Renzheng; Liu, Lijun; Wang, Baoxin; Xu, Yongnan

2010-11-01

The previous work proved that the bovine serum albumin (BSA) could be damaged under the combined action of ultrasonic irradiation and ZnO. In this work, the assisted sonocatalytic damage of BSA using metronidazole (MTZ) as a sensitizer was further investigated by means of UV-vis and fluorescence spectra. The results indicated that the adding of MTZ could obviously promote the sonocatalytic damage of BSA under ultrasonic irradiation in the presence of nano-sized ZnO powder. Furthermore, it was found that the damage degree of BSA was aggravated by some influencing factors except ionic kind and strength. In addition, the damage site of BSA was also studied with synchronous fluorescence technology. It was found that the damage site was mainly at tryptophan (Trp) residue.

Heat stress management program improving worker health and operational effectiveness: a case study.

PubMed

Huss, Rosalyn G; Skelton, Scott B; Alvis, Kimberly L; Shane, Leigh A

2013-03-01

Heat stress monitoring is a vital component of an effective health and safety program when employees work in exceptionally warm environments. Workers at hazardous waste sites often wear personal protective equipment (PPE), which increases the body heat stress load. No specific Occupational Safety and Health Administration (OSHA) regulations address heat stress; however, OSHA does provide several guidance documents to assist employers in addressing this serious workplace health hazard. This article describes a heat stress and surveillance plan implemented at a hazardous waste site as part of the overall health and safety program. The PPE requirement for work at this site, coupled with extreme environmental temperatures, made heat stress a significant concern. Occupational health nurses and industrial hygienists developed a monitoring program for heat stress designed to prevent the occurrence of significant heat-related illness in site workers. The program included worker education on the signs of heat-related illness and continuous physiologic monitoring to detect early signs of heat-related health problems. Biological monitoring data were collected before workers entered the exclusion zone and on exiting the zone following decontamination. Sixty-six site workers were monitored throughout site remediation. More than 1,700 biological monitoring data points were recorded. Outcomes included improved worker health and safety, and increased operational effectiveness. Copyright 2013, SLACK Incorporated.

Search for underground openings for in situ test facilities in crystalline rock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wollenberg, H.A.; Strisower, B.; Corrigan, D.J.

1980-01-01

With a few exceptions, crystalline rocks in this study were limited to plutonic rocks and medium to high-grade metamorphic rocks. Nearly 1700 underground mines, possibly occurring in crystalline rock, were initially identified. Application of criteria resulted in the identification of 60 potential sites. Within this number, 26 mines and 4 civil works were identified as having potential in that they fulfilled the criteria. Thirty other mines may have similar potential. Most of the mines identified are near the contact between a pluton and older sedimentary, volcanic and metamorphic rocks. However, some mines and the civil works are well within plutonicmore » or metamorphic rock masses. Civil works, notably underground galleries associated with pumped storage hydroelectric facilities, are generally located in tectonically stable regions, in relatively homogeneous crystalline rock bodies. A program is recommended which would identify one or more sites where a concordance exists between geologic setting, company amenability, accessibility and facilities to conduct in situ tests in crystalline rock.« less

Investigative studies for the use of an inactive asbestos mine as a disposal site for asbestos wastes.

PubMed

Gidarakos, Evangelos; Anastasiadou, Kalliopi; Koumantakis, Emmanuil; Nikolaos, Stappas

2008-05-30

Although, according to European legislation the use of Asbestos Containing Materials is forbidden, many buildings in Greece still contain asbestos products, which must be removed at some point in the near future. Therefore, suitable disposal sites must be found within Greece, so that the unverified disposal of asbestos waste in municipal waste Landfills is brought to an end. In the present work, an innovative approach to the disposal problem of asbestos wastes in Greece has been examined, through a risk assessment analysis of the inactive asbestos mine of Northern Greece and an evaluation of its suitability as a disposal site for asbestos wastes in the future. According to the research carried out, two areas (Site 1 and Site 2) inside the mine area are suitable for the construction of a disposal site for asbestos wastes. The geological investigations showed that in Site 1 and Site 2 ultrabasic rocks of ophiolite complex were prevalent, which have been intensely serpentinized and converted into the fibrous shape of serpentine (asbestos). Concentrations of hazardous substances such as heavy metals in the soil of Site 1 and Site 2 oscillate at low levels, with the exception of the concentrations of nickel and chrome which are high. The investigative work also included the collection of meteorological data and the monitoring of the water level of the artificial lake, which has developed inside the open mine. The main aim is to safely dispose asbestos wastes inside the mine, to minimize any pollution of the wider vicinity of the mine, as well as to engage in restoration activities.

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

Effects of urban density on carbon dioxide exchanges: Observations of dense urban, suburban and woodland areas of southern England.

PubMed

Ward, H C; Kotthaus, S; Grimmond, C S B; Bjorkegren, A; Wilkinson, M; Morrison, W T J; Evans, J G; Morison, J I L; Iamarino, M

2015-03-01

Anthropogenic and biogenic controls on the surface-atmosphere exchange of CO2 are explored for three different environments. Similarities are seen between suburban and woodland sites during summer, when photosynthesis and respiration determine the diurnal pattern of the CO2 flux. In winter, emissions from human activities dominate urban and suburban fluxes; building emissions increase during cold weather, while traffic is a major component of CO2 emissions all year round. Observed CO2 fluxes reflect diurnal traffic patterns (busy throughout the day (urban); rush-hour peaks (suburban)) and vary between working days and non-working days, except at the woodland site. Suburban vegetation offsets some anthropogenic emissions, but 24-h CO2 fluxes are usually positive even during summer. Observations are compared to estimated emissions from simple models and inventories. Annual CO2 exchanges are significantly different between sites, demonstrating the impacts of increasing urban density (and decreasing vegetation fraction) on the CO2 flux to the atmosphere. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

A Regional Analysis of Non-Methane Hydrocarbons And Meteorology of The Rural Southeast United States

DTIC Science & Technology

1996-01-01

Zt is an ARIMA time series. This is a typical regression model , except that it allows for autocorrelation in the error term Z. In this work, an ARMA...data=folder; var residual; run; II Statistical output of 1992 regression model on 1993 ozone data ARIMA Procedure Maximum Likelihood Estimation Approx...at each of the sites, and to show the effect of synoptic meteorology on high ozone by examining NOAA daily weather maps and climatic data

Microplastics in sediments from the littoral zone of the north Tunisian coast (Mediterranean Sea)

NASA Astrophysics Data System (ADS)

Abidli, Sami; Antunes, Joana C.; Ferreira, Joana L.; Lahbib, Youssef; Sobral, Paula; Trigui El Menif, Najoua

2018-05-01

The distribution of microplastics (MPs) was investigated in the sediments of five sampling sites from the northern Tunisian coast during June 2017. MPs were categorized according to type, colour and size. Representative MPs from the five sites were isolated for polymer identification using Fourier Transformed Infrared Spectroscopy in attenuated total reflectance mode (FTIR-ATR). Results showed that MPs were recovered, from all sediment samples, indicating for the first time, their extensive distribution in Tunisian coast. Concentrations varied from 141.20 ± 25.98 to 461.25 ± 29.74 items kg-1 dry weight. Fibres, fragments, Styrofoam®, pellets and films were the types registered in this study. With the exception of Menzel Bourguiba (MB), fibres significantly outnumbered plastic particles followed by fragments, Styrofoam®, films and pellets. The predominant colours are as follows: black > clear > white > red > blue > green for fibres, blue > white > clear > red > green > yellow > black for fragments, blue > white > black > clear for films while only white pellets and Styrofoam® were found. MPs particles ranged from 0.1 to 5 mm in length. A total of three polymer types were identified, polyethylene (PE), polypropylene (PP) and polystyrene (PS). Except for industrial pellets, the presence of MPs is likely due to the degradation of marine plastic debris accumulating in each site. This work provides original data of the presence of MPs in coastal sediments from Northern Tunisian coast.

Assessment of the long-term impacts of PM10 and PM2.5 particles from construction works on surrounding areas.

PubMed

Azarmi, Farhad; Kumar, Prashant; Marsh, Daniel; Fuller, Gary

2016-02-01

Construction activities are common across cities; however, the studies assessing their contribution to airborne PM10 (≤10 μm) and PM2.5 (≤2.5 μm) particles on the surrounding air quality are limited. Herein, we assessed the impact of PM10 and PM2.5 arising from construction works in and around London. Measurements were carried out at 17 different monitoring stations around three construction sites between January 2002 and December 2013. Tapered element oscillating microbalance (TEOM 1400) and OSIRIS (2315) particle monitors were used to measure the PM10 and PM2.5 fractions in the 0.1-10 μm size range along with the ambient meteorological data. The data was analysed using bivariate concentration polar plots and k-means clustering techniques. Daily mean concentrations of PM10 were found to exceed the European Union target limit value of 50 μg m(-3) at 11 monitoring stations but remained within the allowable 35 exceedences per year, except at two monitoring stations. In general, construction works were found to influence the downwind concentrations of PM10 relatively more than PM2.5. Splitting of the data between working (0800-1800 h; local time) and non-working (1800-0800 h) periods showed about 2.2-fold higher concentrations of PM10 during working hours when compared with non-working hours. However, these observations did not allow to conclude that this increase was from the construction site emissions. Together, the polar concentration plots and the k-means cluster analysis applied to a pair of monitoring stations across the construction sites (i.e. one in upwind and the other in downwind) confirmed the contribution of construction sources on the measured concentrations. Furthermore, pairing the monitoring stations downwind of the construction sites showed a logarithmic decrease (with R(2) about 0.9) in the PM10 and PM2.5 concentration with distance. Our findings clearly indicate an impact of construction activities on the nearby downwind areas and a need for developing mitigation measures to limit their escape from the construction sites.

Climate Variability and Oceanographic Settings Associated with Interannual Variability in the Initiation of Dinophysis acuminata Blooms

PubMed Central

Díaz, Patricio A.; Reguera, Beatriz; Ruiz-Villarreal, Manuel; Pazos, Yolanda; Velo-Suárez, Lourdes; Berger, Henrick; Sourisseau, Marc

2013-01-01

In 2012, there were exceptional blooms of D. acuminata in early spring in what appeared to be a mesoscale event affecting Western Iberia and the Bay of Biscay. The objective of this work was to identify common climatic patterns to explain the observed anomalies in two important aquaculture sites, the Galician Rías Baixas (NW Spain) and Arcachon Bay (SW France). Here, we examine climate variability through physical-biological couplings, Sea Surface Temperature (SST) anomalies and time of initiation of the upwelling season and its intensity over several decades. In 2012, the mesoscale features common to the two sites were positive anomalies in SST and unusual wind patterns. These led to an atypical predominance of upwelling in winter in the Galician Rías, and increased haline stratification associated with a southward advection of the Gironde plume in Arcachon Bay. Both scenarios promoted an early phytoplankton growth season and increased stability that enhanced D. acuminata growth. Therefore, a common climate anomaly caused exceptional blooms of D. acuminata in two distant regions through different triggering mechanisms. These results increase our capability to predict intense diarrhetic shellfish poisoning outbreaks in the early spring from observations in the preceding winter. PMID:23959151

Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data.

PubMed

Jarvik, Jeffrey G; Comstock, Bryan A; Heagerty, Patrick J; Turner, Judith A; Sullivan, Sean D; Shi, Xu; Nerenz, David R; Nedeljkovic, Srdjan S; Kessler, Larry; James, Kathryn; Friedly, Janna L; Bresnahan, Brian W; Bauer, Zoya; Avins, Andrew L; Deyo, Richard A

2014-04-23

Back pain represents a substantial burden globally, ranking first in a recent assessment among causes of years lived with disability. Though back pain is widely studied among working age adults, there are gaps with respect to basic descriptive epidemiology among seniors, especially in the United States. Our goal was to describe how pain, function and health-related quality of life vary by demographic and geographic factors among seniors presenting to primary care providers with new episodes of care for back pain. We examined baseline data from the Back pain Outcomes using Longitudinal Data (BOLD) registry, the largest inception cohort to date of seniors presenting to a primary care provider for back pain. The sample included 5,239 patients ≥ 65 years old with a new primary care visit for back pain at three integrated health systems (Northern California Kaiser-Permanente, Henry Ford Health System [Detroit], and Harvard Vanguard Medical Associates [Boston]). We examined differences in patient characteristics across healthcare sites and associations of patient sociodemographic and clinical characteristics with baseline patient-reported measures of pain, function, and health-related quality of life. Patients differed across sites in demographic and other characteristics. The Detroit site had more African-American patients (50%) compared with the other sites (7-8%). The Boston site had more college graduates (68%) compared with Detroit (20%). Female sex, lower educational status, African-American race, and older age were associated with worse functional disability as measured by the Roland-Morris Disability Questionnaire. Except for age, these factors were also associated with worse pain. Baseline pain and functional impairment varied substantially with a number of factors in the BOLD cohort. Healthcare site was an important factor. After controlling for healthcare site, lower education, female sex, African-American race, and older age were associated with worse physical disability and all of these factors except age were associated with worse pain. Clinical Trials.gov NCT01776242; Registration date: June 13, 2012.

Trends in the levels of halogenated flame retardants in the Great Lakes atmosphere over the period 2005-2013.

PubMed

Liu, Liang-Ying; Salamova, Amina; Venier, Marta; Hites, Ronald A

2016-01-01

Air (vapor and particle phase) samples were collected every 12days at five sites near the North American Great Lakes from 1 January 2005 to 31 December 2013 as a part of the Integrated Atmospheric Deposition Network (IADN). The concentrations of 35 polybrominated diphenyl ethers (PBDEs) and eight other halogenated flame retardants were measured in each of the ~1,300 samples. The levels of almost all of these flame retardants, except for pentabromoethylbenzene (PBEB), hexabromobenzene (HBB), and Dechlorane Plus (DP), were significantly higher in Chicago, Cleveland, and Sturgeon Point. The concentrations of PBEB and HBB were relatively high at Eagle Harbor and Sturgeon Point, respectively, and the concentrations of DP were relatively high at Cleveland and Sturgeon Point, the two sites closest to this compound's production site. The data were analyzed using a multiple linear regression model to determine significant temporal trends in these atmospheric concentrations. The concentrations of PBDEs were decreasing at the urban sites, Chicago and Cleveland, but were generally unchanging at the remote sites, Sleeping Bear Dunes and Eagle Harbor. The concentrations of PBEB were decreasing at almost all sites except for Eagle Harbor, where the highest PBEB levels were observed. HBB concentrations were decreasing at all sites except for Sturgeon Point, where HBB levels were the highest. DP concentrations were increasing with doubling times of 3-9years at all sites except those closest to its source (Cleveland and Sturgeon Point). The levels of 1,2-bis(2,4,6-tribromophenoxy)ethane (TBE) were unchanging at the urban sites, Chicago and Cleveland, but decreasing at the suburban and remote sites, Sturgeon Point and Eagle Harbor. The atmospheric concentrations of 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EHTBB) and bis(2-ethylhexyl)-tetrabromophthalate (BEHTBP) were increasing at almost every site with doubling times of 3-6years. Copyright © 2016 Elsevier Ltd. All rights reserved.

Sixth International Limnogeology Congress: field trip guidebook, Reno, Nevada, June 15-19, 2015

USGS Publications Warehouse

Rosen, Michael R.

2015-01-01

The U.S. Geological Survey has sponsored each ILIC that has been held in the United States because of the importance of understanding paleoclimate and contaminant histories of lakes, two main themes of the Congress. This field trip guide provides a permanent record of some of the wide variety of studies that are being conducted in modern lakes and ancient lake deposits in western North America, and it provides a starting point for any one desiring to visit these exceptional sites or begin work in these areas.

Nevada National Security Site Industrial Sites Project Closeout - 12498

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cabble, Kevin; Krauss, Mark; Matthews, Pat

The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office is responsible for environmental restoration (ER) at the Nevada National Security Site (NNSS). This includes remediation at Industrial Sites where past nuclear testing activities and activities that supported nuclear testing may have or are known to have resulted in the release of contaminants into the environment. Industrial Sites at the NNSS have included nuclear facilities that supported the nuclear rocket/missile development programs, gas stations, landfills, spill sites, ordnance sites, and numerous other waste disposal and release sites. The NNSS Industrial Sites activities neared completion at the endmore » of fiscal year 2011 while other activities required under the Federal Facility Agreement and Consent Order (FFACO) and part of the same NNSS ER Project are forecasted to extend to 2027 or beyond. With the majority of Industrial Sites corrective action units (CAUs) completed (more than 250 CAUs and over 1,800 corrective action sites), it was determined that an activity closeout process should be implemented to ensure that the work completed over the past 15 years is well documented in a comprehensive and concise summary. While the process used to close each individual CAU is described in approved documents, no single document describes in summary fashion the work completed to close the many individual Industrial Sites. The activity closeout process will be used to develop an Industrial Sites closeout document that describes these years of work. This document will summarize the number of Industrial Sites closed under the FFACO and provide general descriptions of projects, contaminants removed, and sites closed in place with corresponding Use Restrictions. Other pertinent information related to Industrial Sites work such as the project history, closure decisions, historical declarations, remediation strategies, and final CAU status will be included in the closeout document, along with a table listing each CAU and corresponding corrective action sites within each CAU. Using this process of conducting the activity closeout and developing a closeout document may prove useful for other ER projects within the DOE complex in describing how a long period of ER can be summarized in a single document. The NNSS Industrial Sites activities were completed over the span of 15 years and involved the investigation, cleanup or Use Restriction, and closure of more than 260 CAUs and over 1,800 sites. These activities will conclude in FY 2012 (with the exception of one CAU). In order to capture the work completed over this length of time and document decisions made during the activities, a closeout effort was initiated. The closeout will review the work conducted during the Industrial Sites activities and produce a single document that summarizes Industrial Sites activities. This closeout is being conducted at an interim stage in the overall NNSA/NSO ER Project since the Soils and UGTA activities will continue for a number of years, but the completion of the Industrial Sites project warrants conducting a closeout now while personnel are available and information is still current. The process followed by NNSA/NSO in conducing project closeout for the Industrial Sites portion of the ER program may prove useful within the DOE complex in demonstrating how a large ER project can be summarized. (authors)« less

Project characteristics monitoring report: BWIP (Basalt Waste Isolation Program) repository project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedli, E.A.; Herborn, D.I.; Taylor, C.D.

1988-03-01

This monitoring report has been prepared to show compliance with provisions of the Nuclear Waste Policy Act of 1982 (NWPA) and to provide local and state government agencies with information concerning the Basalt Waste Isolation Program (BWIP). This report contains data for the time period May 26, 1986 to February 1988. The data include employment figures, salaries, project purchases, taxes and fees paid, worker survey results, and project closedown personal interview summaries. This information has become particularly important since the decision in December 1987 to stop all BWIP activities except those for site reclamation. The Nuclear Waste Policy Amendments Actmore » of 1987 requires nonreclamation work at the Hanford Site to stop as of March 22, 1988. 7 refs., 6 figs., 28 tabs.« less

Geologic features of dam sites in the Nehalem, Rogue, and Willamette River basins, Oregon, 1935-37

USGS Publications Warehouse

Piper, A.M.

1947-01-01

The present report comprises brief descriptions of geologic features at 19 potential dam sites in the Nehalem, Rogue, and Willamette River basins in western Oregon. The topography of these site and of the corresponding reservoir site was mapped in 1934-36 under an allocation of funds, by the Public Works Administration for river-utilization surveys by the Conservation Branch of the United States Geological Survey. The field program in Oregon has been under the immediate charge of R. O. Helland. The 19 dam sites are distributed as follows: three on the Nehalem River, on the west or Pacific slope of the Oregon Coast range; four on Little Butte Creek and two on Evans Creek, tributaries of the Rogue River in the eastern part of the Klamath Mountains; four on the South and Middle Santiam Rivers, tributaries of the Willamette River from the west slope of the Cascade mountains; and six on tributaries of the Willamette River from the east slope of the Coast Range. Except in the Evans Creek basin, all the rocks in the districts that were studied are of comparatively late geological age. They include volcanic rocks, crystalline rocks of several types, marine and nonmarine sedimentary rocks, and recent stream deposits. The study of geologic features has sought to estimate the bearing power and water-tightness of the rocks at each dam site, also to place rather broad limits on the type of dam for which the respective sites seem best suited. It was not considered necessary to study the corresponding reservoir sites in detail for excessive leakage appears to be unlikely. Except at three of the four site in the Santiam River basin, no test pits have been dug nor exploratory holes drilled, so that geologic features have been interpreted wholly from natural outcrops and from highway and railroad cuts. Because these outcrops and cuts are few, many problems related to the construction and maintenance of dams can not be answered at the this time and all critical features of the sites should be thoroughly explored by test pits and drilled holes before any dam is designed. This applied especially to sites in the Nehalem and Willamette River basins where commonly the cover of timber and brush is dense and the rocks are rather deeply weathered. On the Middle Santiam and South Santiam Rivers, the Cascadia, Greenpeter, and Sweet Home sits have been studies intensively by the United States Engineer Department, whose work included exploration by diamond-drill holes and test pits. Their conclusions as to geologic features are given in a report by McKitrick and have been reviewed by the writer. Data from this source have been used freely in the discussion of the respective sites in this report. The probability of destructive earthquakes in the region appears to be small but is not negligible. Prudence suggests that any high dam should embody features to assure stability against moderately strong earth motions.

Possibility of a ferromagnetic and conducting metal-organic network

NASA Astrophysics Data System (ADS)

Mabrouk, Manel; Hayn, Roland; Denawi, Hassan; Ben Chaabane, Rafik

2018-05-01

In this paper, we present first principles calculations based on the spin-polarized generalized gradient approximation with on-site Coulomb repulsion term (SGGA + U), to explore the electronic and magnetic properties of the novel planar metal-organic networks TM-Pc and TM-TCNB (where TM means a transition metal of the 3d series: Ti, V, Cr, …, or Zn, Pc - Phthalocyanine, and TCNB - Tetracyanobenzene) as free-standing sheets. This work is an extension of two earlier research works dealing with the Mn (Mabrouk et al., 2015) and Fe (Mabrouk et al., 2017) cases. Our theoretical investigations demonstrate that TM-Pc are more stable than TM-TCNB. Our results unveil that all the TM-Pc frameworks have an insulating behavior with the exception of Mn-Pc which is half-metallic and favor antiferromagnetic order in the case of our magnetic systems except for V-Pc which is ferromagnetic. In contrast, the TM-TCNB networks are metallic at least in one spin direction and exhibit long-range ferromagnetic coupling in case for magnetic structures, which represent ideal candidates and an interesting prospect of unprecedented applications in spintronics. In addition, these results may shed light to achieve a new pathway on further experimental research in molecular spintronics.

Interfacial microstructure in a B{sub 4}C/Al composite fabricated by pressureless infiltration.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, Z.; Song, Y.; Zhang, S.

In this work, B{sub 4}C particulate-reinforced Al composite was fabricated by a pressureless infiltration technique, and its interfacial microstructure was studied in detail by X-ray diffraction as well as by scanning and transmission electron microscopy. The B{sub 4}C phase was unstable in Al melt during the infiltration process, forming AlB{sub 10}-type AlB{sub 24}C{sub 4} or Al{sub 2.1}B{sub 51}C{sub 8} as a major reactant phase. The Al matrix was large grains (over 10 {micro}m), which had no definite orientation relationships (ORs) with the randomly orientated B{sub 4}C or its reactant particles, except for possible nucleation sites with {l_brace}011{r_brace}{sub B{sub 4}C} almostmore » parallel to {l_brace}111{r_brace}{sub Al} at a deviation angle of 1.5 deg. Both B{sub 4}C-Al and reactant-Al interfaces are semicoherent and free of other phases. A comparison was made with the SiC/Al composite fabricated similarly by the pressureless infiltration. It was suggested that the lack of ORs between the Al matrix and reinforced particles, except for possible nucleation sites, is the common feature of the composites prepared by the infiltration method.« less

Assessment of the physicochemical conditions sediments in a polluted tidal flat colonized by microbial mats in Bahía Blanca Estuary (Argentina).

PubMed

Spetter, C V; Buzzi, N S; Fernández, E M; Cuadrado, D G; Marcovecchio, J E

2015-02-28

The aim of this work is to assess the physicochemical conditions of the supratidal sediments colonized by microbial mats at two sites from Rosales Harbor (Bahía Blanca Estuary, Argentina) close to sewage discharge. Both sites differed in the size grain. No differences in pH, Eh and temperature were observed. Moisture retention and chlorophyll a concentration were significantly different between sites and sediment layers. Heavy metals and organic matter content were significantly higher in SII. No statistical differences were found in porewater nutrients concentration, being higher in SI (except DSi). The presence of Escherichia coli in water and sediment (1000 CFU/100 mL - uncountable and 35-40 CFU g(-1) dw, respectively) evidenced microbial contamination in the study area. The relationships between the physicochemical parameters evaluated and the influence of the sewage discharge allow defining two different areas in the Rosales Harbor despite the proximity and the presence of microbial mats.

Biological Activity and Binding Site Characteristics of the PA1b Entomotoxin on Insects from Different Orders

PubMed Central

Gressent, Frédéric; Duport, Gabrielle; Rahioui, Isabelle; Pauchet, Yannick; Bolland, Patrice; Specty, Olivier; Rahbe, Yvan

2007-01-01

The aim of this work was to investigate both the biological activity of an entomotoxin, the pea albumin 1b (PA1b), and the presence or absence of its binding site within an array of insect species. The data obtained showed that insect sensitivity was not related to its taxonomic position. Moreover, PA1b was not toxic to several tested microorganisms. However, the binding site was found to be conserved among very different insects, displaying similar thermodynamic constants regardless of the in vivo species sensitivity. The binding site alone was, therefore, not sufficient for toxicity. One exception was the pea weevil, Bruchus pisorum, which was the only tested species without any detectable binding activity. These findings indicate that the binding site probably has an important endogenous function in insects and that adaptation to pea seeds resulted in the elimination of the toxin binding activity in two independent insect lineages. Other mechanisms are likely to interact with the toxin effects, although they are still largely unknown, but there is no evidence of any specific degradation of PA1b in the midgut of insects insensitive to the toxin, such as Drosophila melanogaster or Mamestra brassicae. PMID:20331395

The changing face of Hanford security 1990--1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thielman, J.

The meltdown of the Cold War was a shock to the systems built to cope with it. At the DOE`s Hanford Site in Washington State, a world-class safeguards and security system was suddenly out of step with the times. The level of protection for nuclear and classified materials was exceptional. But the cost was high and the defense facilities that funded security were closing down. The defense mission had created an umbrella of security over the sprawling Hanford Site. Helicopters designed to ferry special response teams to any trouble spot on the 1,456 square-kilometer site made the umbrella analogy almostmore » literally true. Facilities were grouped into areas, fenced off like a military base, and entrance required a badge check for everyone. Within the fence, additional rings of protection were set up around security interests or targets. The security was effective, but costly to operate and inconvenient for employees and visitors alike. Moreover, the umbrella meant that virtually all employees needed a security clearance just to get to work, whether they worked on classified or unclassified projects. Clearly, some fundamental rethinking of safeguards and security was needed. The effort to meet that challenge is the story of transition at Hanford and documented here.« less

Geoheritage Values at Greenmantle Farm

NASA Astrophysics Data System (ADS)

Etches, J. D.

2009-05-01

The Greenmantle Farm occurrence near Wilberforce, Ontario is a marble feature within the Grenville Province of the Precambrian Shield that hosts a diverse suite of amphibole minerals. The marble is of undetermined petrogenesis, and is possibly either a primary carbonatite intrusion or a derived melt of metasedimentary origin. The site is the type locality for the rare mineral fluorrichterite. Other minerals of note are orthoclase and apatite. Crystal size is relatively large, and all minerals, with the exception of calcite, exhibit generally good to excellent euhedral form. Of note is that the mineral occurrences at this site have not been subjected to any human disturbance including mechanical or hand tool disruption. The site also provides excellent examples of a number of geological features and ecosystem dynamics. In particular, faulting, moisture regime landscape interrelationships, order of crystallization in zoned dykes, and calciphile plant associations are demonstrated. This site represents an exceptional viewing opportunity of an unspoiled mineral occurrence while providing illustrative examples of the interrelationship of abiotic and biotic features. In terms of research, the site will prove to be a valuable subject in regard to amphibole composition, amphibole differentiation in calcareous melts, and will ultimately provide insight into the formation of the occurrence. Determination of what circumstances these marble bodies formed under would add a significant piece of information to the complex history of the Grenville province. This research will be assisted by the completely uncompromised nature of the site. The potential educational value of the site for researchers and grade school students alike is exceptional.

Envitonmental monitoring and radiation protection in Škocjan Caves, Slovenia

NASA Astrophysics Data System (ADS)

Debevec Gerjeviè, V.; Jovanovič, P.

2012-04-01

Škocjan Caves were listed as UNESCO World Heritage Sites in 1986, due to their exceptional significance for cultural and natural heritage. Park Škocjan Caves is located in South Eastern part of Slovenia. It was established with aim of conserving and protecting exceptional geomorphological, geological and hydrological outstanding features, rare and endangered plant and animal species, paleontological and archaeological sites, ethnological and architectural characteristics and cultural landscape and for the purpose of ensuring opportunities for suitable development, by the National Assembly of the Republic of Slovenia in 1996. Park Škocjan Caves established monitoring that includes caves microclimate parameters: humidity, CO2, wind flow and radon concentration and daughter products. The approach in managing the working place with natural background radiation is complex. Monitoring of Radon has been functioning for more than ten years now. Presentation will show the dynamic observed in the different parts of the caves, related to radon daughter products and other microclimatic data. Relation of background radiation to carrying capacity will be explained. Implementing the Slovene legislation in the field of radiation protection, we are obligated to perform special measurements in the caves and also having our guides and workers in the caves regularly examined according to established procedure. The medical exams are performed at Institution of Occupational Safety, Ljubljana in order to monitor the influence of Radon to the workers in the cave. The equivalent dose for each employed person is also established on regular basis and it is part of medical survey of workers in the caves. A system of education of the staff working in the caves in the field of radiation protection will be presented as well.

Comparison of Methods of Detection of Exceptional Sequences in Prokaryotic Genomes.

PubMed

Rusinov, I S; Ershova, A S; Karyagina, A S; Spirin, S A; Alexeevski, A V

2018-02-01

Many proteins need recognition of specific DNA sequences for functioning. The number of recognition sites and their distribution along the DNA might be of biological importance. For example, the number of restriction sites is often reduced in prokaryotic and phage genomes to decrease the probability of DNA cleavage by restriction endonucleases. We call a sequence an exceptional one if its frequency in a genome significantly differs from one predicted by some mathematical model. An exceptional sequence could be either under- or over-represented, depending on its frequency in comparison with the predicted one. Exceptional sequences could be considered biologically meaningful, for example, as targets of DNA-binding proteins or as parts of abundant repetitive elements. Several methods to predict frequency of a short sequence in a genome, based on actual frequencies of certain its subsequences, are used. The most popular are methods based on Markov chain models. But any rigorous comparison of the methods has not previously been performed. We compared three methods for the prediction of short sequence frequencies: the maximum-order Markov chain model-based method, the method that uses geometric mean of extended Markovian estimates, and the method that utilizes frequencies of all subsequences including discontiguous ones. We applied them to restriction sites in complete genomes of 2500 prokaryotic species and demonstrated that the results depend greatly on the method used: lists of 5% of the most under-represented sites differed by up to 50%. The method designed by Burge and coauthors in 1992, which utilizes all subsequences of the sequence, showed a higher precision than the other two methods both on prokaryotic genomes and randomly generated sequences after computational imitation of selective pressure. We propose this method as the first choice for detection of exceptional sequences in prokaryotic genomes.

Characterizing Early Succession Following Wildfires at Different Severities in Boreal Bog and Fen Peatlands

NASA Astrophysics Data System (ADS)

Ernst, E. J.; Bourgeau-Chavez, L. L.; Kane, E. S.; Wagenbrenner, J. W.; Endres, S.

2016-12-01

The Arctic-boreal region is experiencing changes in climate, trending toward warmer summers, resulting in a greater occurrence of wildfires with longer burning periods and higher intensities. Drought-like conditions have dried surface fuels, leading to a higher probability of ignition, even in lowland peatlands. Previous work has been done to characterize post-fire succession rates in Arctic-boreal upland sites, but much less is known of fire effects and early successional dynamics in lowlands. Wildland fires are the number one disturbance in Canada's Northwest Territories (NWT), which characteristically burn at high intensities with large flame fronts, and result in some of the biggest wildfires in the world. Areas surrounding the Great Slave Lake, NWT—including parts of the Taiga Plains, Taiga Shield, and Boreal Plains ecozones—experienced exceptional wildfire activity in 2014 and 2015. We characterized burn severity of the bog and fen peat surface and canopy layers at several burned sites. To determine if the severe ground or crown wildfires were stand-replacing events, we characterized post-fire vegetation in peatlands in 2015 and 2016 based on seedling regeneration. We stratified sites according to estimated water residence times across the three ecozones and made comparisons between data collected at the same sites across years. This work adds much needed context for post-fire succession in boreal peatland ecosystems, as the susceptibility of these systems to burning will continue to increase with a warming climate.

9 CFR 149.3 - Site audit.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... as follows: (1) The movement of all non-breeding swine 5 weeks of age or older into or from the pork... previous site (if applicable). (2) All non-breeding swine entering a site must have originated from another certified production site, except that non-breeding swine less than 5 weeks of age may have originated from...

9 CFR 149.3 - Site audit.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... as follows: (1) The movement of all non-breeding swine 5 weeks of age or older into or from the pork... previous site (if applicable). (2) All non-breeding swine entering a site must have originated from another certified production site, except that non-breeding swine less than 5 weeks of age may have originated from...

9 CFR 149.3 - Site audit.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... as follows: (1) The movement of all non-breeding swine 5 weeks of age or older into or from the pork... previous site (if applicable). (2) All non-breeding swine entering a site must have originated from another certified production site, except that non-breeding swine less than 5 weeks of age may have originated from...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2011 CFR

2011-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2013 CFR

2013-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2012 CFR

2012-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2014 CFR

2014-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

7 CFR 1822.278 - Special requirements for RHS section 523 loans (loans to organizations providing sites for self...

Code of Federal Regulations, 2010 CFR

2010-01-01

... to organizations providing sites for self-help housing). 1822.278 Section 1822.278 Agriculture... organizations providing sites for self-help housing). Loans to organizations which will provide sites for self... exceptions: (a) Eligibility. The applicant must be a nonprofit organization engaged in assisting self-help...

Development of a 3D Model for the Assessment of Vulnerability Due to Sea Level Rise on the Historic Strawbery Banke

NASA Astrophysics Data System (ADS)

Jefferson, M.; Curran, B.; Routhier, M.; Mulukutla, G. K.; Hall, C. L.

2011-12-01

The study of climate change is now starting to be widely researched around the world. One prominent exception to this fact is within the discipline of Historic Preservation. With the likelihood of climate change causing sea levels to rise over decades to come, historical preservationists are now looking for data and information which can help them mitigate potential threats to our cultural heritage along our sea coasts. Some such information that can be helpful in understanding these threats includes geographic information such as the locations of artifacts, fossils, and historic structures as well as their vertical elevation above mean sea level. In an effort to build a set of protocols to help preservations study these threats, our work is currently focusing on a historic living history museum site known as Strawbery Banke in Portsmouth, New Hampshire. This poster features a subset of this work that was completed through undergraduate student internships funded by the Joan and James Leitzel Center at the University of New Hampshire. This subset of work focused on the creation a 3D model of the study site. Two aspects of the creation of this model involved the completion of a topographic ground survey and the 3D digital mapping of the site itself. The ground survey was completed with the use of standard surveying techniques and tools and the 3D digital mapping was completed with the use of ArcScene, a software which is part of the ArcGIS suite. This work was completed in conjunction with a larger study funded by the National Geographic Society to better understand how sea level rise and the effects of storm surges are putting the historic structures at Strawbery Banke at risk.

Distribution and sources of aliphatic hydrocarbons in surface sediments of Sergipe River estuarine system.

PubMed

Lima, Manoel B; Feitosa, Elaine A; Emídio, Elissandro S; Dórea, Haroldo S; Alexandre, Marcelo R

2012-08-01

The assessment of aliphatic hydrocarbons was performed in the Sergipe River estuarine system, northeastern Brazil. Aliphatic hydrocarbons concentration ranged from 9.9 ug g⁻¹ up to 30.8 ug g⁻¹ of dry sediment. The carbon preference index (CPI, based on nC₂₄ to nC₃₄ range), indicated predominance of petrogenic input in two of the sites analyzed (P4 and P5). The unresolved complex mixture (UCM) was found to be present in seven of the nine sites sampled (except for P4 and P5). Overall, the results of this work suggest that there is a mix of organic matter sources to the sediment. Although the coast of Sergipe has an intense off shore petroleum exploration and the Sergipe River crosses the entire city of Aracaju, the capital city of Sergipe, non-significant anthropogenic fingerprint was assessed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Electric and hybrid vehicle program; Site Operator Program

NASA Astrophysics Data System (ADS)

Warren, J. F.

1992-05-01

Activities during the second quarter included the second meeting of the Site Operators in Phoenix, AZ in late April. The meeting was held in conjunction with the Solar and Electric 500 Race activities. Delivery of vehicles ordered previously has begun, although two of the operators are experiencing some delays in receiving their vehicles. Public demonstration activities continue, with an apparent increasing level of awareness and interest being displayed by the public. Initial problems with the Site Operator Database have been corrected and revised copies of the program have been supplied to the program participants. Operating and Maintenance data is being supplied and submitted to INEL on a monthly basis. Interest in the Site Operator Program is being reflected in requests for information from several organizations from across the country, representing a wide diversity of interests. These organizations have been referred to existing Site Operators with the explanation that the program will not be adding new participants, but that most of the existing organizations are willing to work with other groups. The exception to this was the addition of Potomac Electric Power Company (PEPCO) to the program. PEPCO has been awarded a subcontract to operate and maintain the DOE owned G-Van and Escort located in Washington, DC. They will provide data on these vehicles, as well as a Solectria Force which PEPCO has purchased. The Task Force intends to be actively involved in the infrastructure development in a wide range of areas. These include, among others, personnel development, safety, charging, and servicing. Work continues in these areas. York Technical College (YORK) has completed the draft outline for the EV Technician course. This is being circulated to organizations around the country for comments. Kansas State University (KSU) is working with a private sector company to develop a energy dispensing meter for opportunity charging in public areas.

Species Identification and Resistance Status of Anopheles gambiae s.l. (Diptera: Culicidae) Mosquitoes in Guinea.

PubMed

Keita, K; Camara, D; Barry, Y; Ossè, R; Wang, L; Sylla, M; Miller, D; Leite, L; Schopp, P; Lawrence, G G; Akogbéto, M; Dotson, E M; Guilavogui, T; Keita, M; Irish, S R

2017-05-01

Insecticide resistance is one of the primary threats to the recent gains in malaria control. This is especially true in Guinea, where long-lasting insecticidal nets are currently the primary vector control intervention. To better inform the national malaria control program on the current status of insecticide resistance in Guinea, resistance bioassays were conducted, using Anopheles gambiae s.l. Giles, in three sites. Molecular analyses were also done on An. gambiae s.l. to determine the species and find whether the target-site mutations kdr and Ace1R were present. Susceptibility tests revealed resistance to DDT and pyrethroids, although mosquitoes were susceptible to deltamethrin in two of the three sites tested. Mosquitoes were susceptible to bendiocarb, except in Kissidougou, Guinea. The kdr-west mutation was widespread and the frequency was 60% or more in all sites. However, the Ace1R mutation was present in low levels. Insecticide susceptibility should continue to be monitored in Guinea to ensure insecticide-based vector control methods remain effective. Published by Oxford University Press on behalf of Entomological Society of America 2017. This work is written by US Government employees and is in the public domain in the US.

AmeriFlux US-Dia Diablo

DOE Data Explorer

Wharton, Sonia [Lawrence Livermore National Laboratory

2016-01-01

This is the AmeriFlux version of the carbon flux data for the site US-Dia Diablo. Site Description - The site is on land owned by Lawrence Livermore National Laboratory (Site 300) and has no grazing or management history since the 1950's except for summer-time burning of selected acres for fire management (not included in the tower footprint).

Soil biological attributes in arsenic-contaminated gold mining sites after revegetation.

PubMed

Dos Santos, Jessé Valentim; de Melo Rangel, Wesley; Azarias Guimarães, Amanda; Duque Jaramillo, Paula Marcela; Rufini, Márcia; Marra, Leandro Marciano; Varón López, Maryeimy; Pereira da Silva, Michele Aparecida; Fonsêca Sousa Soares, Cláudio Roberto; de Souza Moreira, Fatima Maria

2013-12-01

Recovery of arsenic contaminated areas is a challenge society faces throughout the world. Revegetation associated with microbial activity can play an essential role in this process. This work investigated biological attributes in a gold mining area with different arsenic contents at different sites under two types of extant revegetation associated with cover layers of the soil: BS, Brachiaria sp. and Stizolobium sp., and LEGS, Acacia crassicarpa, A. holosericea, A. mangium, Sesbania virgata, Albizia lebbeck and Pseudosamanea guachapele. References were also evaluated, comprising the following three sites: B1, weathered sulfide substrate without revegetation; BM, barren material after gold extraction and PRNH (private reserve of natural heritage), an uncontaminated forest site near the mining area. The organic and microbial biomass carbon contents and substrate-induced respiration rates for these sites from highest to lowest were: PRNH > LEGS > BS > B1 and BM. These attributes were negatively correlated with soluble and total arsenic concentration in the soil. The sites that have undergone revegetation (LEGS and BS) had higher densities of bacteria, fungi, phosphate solubilizers and ammonium oxidizers than the sites without vegetation. Principal component analysis showed that the LEGS site grouped with PRNH, indicating that the use of leguminous species associated with an uncontaminated soil cover layer contributed to the improvement of the biological attributes. With the exception of acid phosphatase, all the biological attributes were indicators of soil recovery, particularly the following: microbial carbon, substrate-induced respiration, density of culturable bacteria, fungi and actinobacteria, phosphate solubilizers and metabolic quotient.

Assessment of On-site sanitation system on local groundwater regime in an alluvial aquifer

NASA Astrophysics Data System (ADS)

Quamar, Rafat; Jangam, C.; Veligeti, J.; Chintalapudi, P.; Janipella, R.

2017-12-01

The present study is an attempt to study the impact of the On-site sanitation system on the groundwater sources in its vicinity. The study has been undertaken in the Agra city of Yamuna sub-basin. In this context, sampling sites (3 nos) namely Pandav Nagar, Ayodhya Kunj and Laxmi Nagar were selected for sampling. The groundwater samples were analyzed for major cations, anions and faecal coliform. Critical parameters namely chloride, nitrate and Faecal coliform were considered to assess the impact of the On-site sanitation systems. The analytical results shown that except for chloride, most of the samples exceeded the Bureau of Indian Standard limits for drinking water for all the other analyzed parameters, i.e., nitrate and faecal coliform in the first two sites. In Laxmi Nagar, except for faecal coliform, all the samples are below the BIS limits. In all the three sites, faecal coliform was found in majority of the samples. A comparison of present study indicates that the contamination of groundwater in alluvial setting is less as compared to hard rock where On-site sanitation systems have been implemented.

A novel method for the study of molecular interaction by using microscale thermophoresis.

PubMed

Mao, Yexuan; Yu, Lanlan; Yang, Ran; Qu, Ling-bo; Harrington, Perter de B

2015-01-01

The fundamental studies for the binding events of protein and its partner are crucial in drug development. In this study, a novel technology named microscale thermophoresis (MST) was applied in the investigation of molecular interaction between an organic dye fluorescein isothiocyanate (FITC) and bovine serum albumin (BSA), and the results were compared with those obtained from conventional fluorescence spectroscopy. The MST data demonstrated that with a short interaction time, FITC showed a high binding affinity for BSA by weak interaction instead of labeling the protein. By using competitive strategies in which warfarin and ibuprofen acted as the site markers of BSA, FITC was proven to mainly bind to the hydrophobic pocket of site II of BSA compared to site I of BSA. Except for the binding affinity, MST also provided additional information with respect to the aggregation of BSA and the binding of FITC to BSA aggregates, which is unobtainable by fluorescence spectroscopy. This work proves that MST as a new approach is powerful and reliable for investigation of protein-small molecule interaction. Copyright © 2014 Elsevier B.V. All rights reserved.

Performance degradation of photovoltaic modules at different sites

NASA Astrophysics Data System (ADS)

Arab, A. Hadj; Mahammed, I. Hadj; Ould Amrouche, S.; Taghezouit, B.; Yassaa, N.

2018-05-01

In this work are presented results of electrical performance measurements of 120 crystalline silicon PV modules following long-term outdoor measurements. A set of 90 PV modules represent the first grid-connected photovoltaic (PV) system in Algeria, installed at the level of the “Centre de Développement des Energies Renouvelables” (CDER) site (Mediterranean coast), Bouzareah. The other 30 PV modules were undertaken in an arid area of the desert region of Ghardaïa site, about 600 km south of Algiers, with measurements collected from different applications. Following different characterization tests, we noticed that the all tested PV modules kept their power-generating rate except a slight reduction. Therefore, a mathematical model has been used to carry out PV module testing at different irradiance and temperature levels. Hence, different PV module parameters have been calculated from the recorded values of the open-circuit voltage, the short-circuit current, the voltage and current at maximum power point. The electrical measurements have indicated different degradations of current-voltage parameters. All the PV modules stated a decrease in the nominal power, which is variable from one module to another.

Excavations at Schöningen and paradigm shifts in human evolution.

PubMed

Conard, Nicholas J; Serangeli, Jordi; Böhner, Utz; Starkovich, Britt M; Miller, Christopher E; Urban, Brigitte; Van Kolfschoten, Thijs

2015-12-01

The exceptional preservation at Schöningen together with a mixture of perseverance, hard work, and sheer luck led to the recovery of unique finds in an exceptional context. The 1995 discovery of numerous wooden artifacts, most notably at least 10 carefully made spears together with the skeletons of at least 20 to 25 butchered horses, brought the debate about hunting versus scavenging among late archaic hominins and analogous arguments about the purportedly primitive behavior of Homo heidelbergensis and Neanderthals to an end. Work under H. Thieme's lead from 1992 to 2008 and results from the current team since 2008 demonstrate that late H. heidelbergensis or early Neanderthals used sophisticated artifacts made from floral and faunal materials, in addition to lithic artifacts more typically recovered at Lower Paleolithic sites. The finds from the famous Horse Butchery Site and two dozen other archaeological horizons from the edges of the open-cast mine at Schöningen provide many new insights into the technology and behavioral patterns of hominins about 300 ka BP during MIS 9 on the Northern European Plain. An analysis of the finds from Schöningen and their contexts shows that the inhabitants of the site were skilled hunters at the top of the food chain and exhibited a high level of planning depth. These hominins had command of effective means of communication about the here and now, and the past and the future, that allowed them to repeatedly execute well-coordinated and successful group activities that likely culminated in a division of labor and social and economic patterns radically different from those of all non-human primates. The unique preservation and high quality excavations have led to a major paradigm shift or "Schöningen Effect" that changed our views of human evolution during the late Lower Paleolithic. In this respect, we can view the behaviors documented at Schöningen as a plausible baseline for the behavioral sophistication of archaic hominins of the late Middle Pleistocene and subsequent periods. Copyright © 2015 Elsevier Ltd. All rights reserved.

20 CFR 220.176 - When disability continues or ends.

Code of Federal Regulations, 2012 CFR

2012-04-01

... related to the annuitant's ability to work. If an impairment(s) has not medically improved, the Board must... related to ability to work has not occurred and no exception applies, the disability will continue. Even the medical improvement related to ability to work has occurred or an exception applies (see § 220.179...

20 CFR 220.176 - When disability continues or ends.

Code of Federal Regulations, 2013 CFR

2013-04-01

... related to the annuitant's ability to work. If an impairment(s) has not medically improved, the Board must... related to ability to work has not occurred and no exception applies, the disability will continue. Even the medical improvement related to ability to work has occurred or an exception applies (see § 220.179...

20 CFR 220.176 - When disability continues or ends.

Code of Federal Regulations, 2014 CFR

2014-04-01

... related to the annuitant's ability to work. If an impairment(s) has not medically improved, the Board must... related to ability to work has not occurred and no exception applies, the disability will continue. Even the medical improvement related to ability to work has occurred or an exception applies (see § 220.179...

Benthic flux of nutrients and trace metals in the northern component of San Francisco Bay, California

USGS Publications Warehouse

Kuwabara, James S.; Topping, Brent R.; Parcheso, Francis; Engelstad, Anita C.; Greene, Valerie E.

2009-01-01

Two sets of sampling trips were coordinated in late summer 2008 (weeks of July 8 and August 6) to sample the interstitial and overlying bottom waters at 10 shallow locations (9 sites <3 meters in depth) within the northern component of the San Francisco Bay/Delta (herein referred to as North Bay). The work was performed to better understand sources of biologically reactive solutes (namely, dissolved macronutrients and trace metals) that may affect the base of the food web in this part of the estuary. A nonmetallic pore-water profiler was used to obtain the first centimeter-scale estimates of the vertical solute-concentration gradients for diffusive-flux determinations. This study, performed in collaboration with scientists from San Francisco State University?s Romberg Tiburon Center for Environmental Studies, provides information to assist in developing and refining management strategies for the Bay/Delta system and supports efforts to monitor changes in food-web structure associated with regional habitat modifications directed by the California Bay-Delta Authority. On July 7, 2008, and August 5, 2008, pore-water profilers were successfully deployed at six North Bay sites per trip to measure the concentration gradient of dissolved macronutrients and trace metals near the sediment-water interface. Only two of the sites (433 and SSB009 within Honker Bay) were sampled in both series of profiler deployments. At each sampling site, profilers were deployed in triplicate, while discrete samples and dataloggers were used to collect ancillary data from both the water column and benthos to help interpret diffusive-flux measurements. Benthic flux of dissolved (0.2-micron filtered) inorganic phosphate (that is, soluble reactive phosphorus (SRP)) ranged from negligible levels (-0.003?0.005 millimole per square meter per day (mmole m-2d-1) at Site 4.1 outside Honker Bay) to 0.060?0.006 mmole m-2d-1 near the northern coast of Brown?s Island. Except for the elevated flux at Browns Island, the benthic flux of soluble reactive phosphorus (SRP) was consistently: (1) lower than previously reported for South Bay sites, (2) an order of magnitude lower than oligotrophic Coeur d?Alene Lake, (3) two orders of magnitude lower than determined for eutrophic Upper Klamath Lake, and (4) an order of magnitude or more lower than the estimated summer riverine inputs for SRP (900 to 1,300 kilograms of phosphorous per day (kg-P d-1)). In contrast to fluxes reported for the South Bay, nitrate fluxes were consistently negative (that is, drawn from the water column into the sediment), except for one site with statistically insignificant nitrate fluxes (Site 409 within Suisun Bay). The most negative nitrate flux (-7.3?0.1 mmole m-2d-1) was observed within Grizzly Bay (Site 416). Observed nitrate fluxes bracketed the estimated summer fluvial flux of nitrate (3,500 to 5,000 kg-N d-1). With the exception of the two Grizzly Bay sites (416 and 417), the consistently positive benthic flux of ammonia generally counteracted the negative flux of nitrate to yield a net balance of dissolved inorganic nitrogen. Ammonia benthic fluxes extrapolated for Suisun Bay ranged from 320 kg-N d-1 (Site SSB009 near the entrance to Honker Bay) to 1,900 kg-N d-1 (Montezuma Island). These values represent a significant ammonia source to the water column relative to summer riverine inputs (approximately 400 to 600 kg-N d-1). Dissolved silica also displayed a consistently positive benthic flux, except for Site 409 within Suisun Bay, which showed insignificant fluxes (also insignificant for nitrate and SRP). As with the nitrate fluxes, Grizzly Bay and Browns Island sites yielded the highest dissolved silica fluxes (1.3?1.2 to 2.5?0.6 mmole m-2d-1, respectively). These initial diffusive-flux estimates are greater than those measured in the South Bay using core-incubation experiments, which include bioturbation and bioirrigation effects, but they are nevertheless probably one to t

Hydrogen sulfide gas emissions in the human-occupied zone during disturbance and removal of stored spent mushroom compost.

PubMed

Velusami, B; Curran, T P; Grogan, H M

2013-10-01

Hydrogen sulfide (H2S) gas levels were monitored in the human-occupied zone at four spent mushroom compost (SMC) storage sites during removal of SMC for application on agricultural land. During SMC removal operations, H2S gas monitors were mounted on the outside of the tractor positioned at the SMC periphery, and worn by individual tractor drivers. The highest H2S concentrations (10 s average) detected outside the tractor, at the SMC periphery, and for the tractor driver were, respectively, 454, 249, and 100 ppm for the outdoor sites and 214, 75, and 51 ppm for the indoor sites. The highest short-term exposure values (STEV over a 15 min period) outside the tractor at the SMC periphery, and for the tractor driver were 147, 55, and 86 ppm for the outdoor sites and 19, 9, and 10 ppm for the indoor sites. The values exceeded the current maximum permissible concentration limit of 10 ppm for all the sites except for the SMC periphery and tractor driver at the indoor sites. Results suggest that H2S levels detected at indoor storage sites during SMC removal are lower compared to outdoor storage sites. Results indicate that there is a substantial health and safety risk associated with working in the vicinity of stored SMC when it is being disturbed and removed for land application, and that the risk is great for the tractor driver. This article discusses possible control measures and lists recommendations to reduce the risks.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Needham, D.; Spearman, A.

This paper describes the design and development of a modular gas control installation which is completely buried, except for a small instrument housing and vent pipe. Buried installations controlling gas pressure have many advantages:- no unsightly or costly housings, protection from damage by vehicles or vandals, no problems of acquisition of sites in built-up areas, no need to divert mains to alternative locations, reduced noise, and easier planning permission associated with environmental aspects. It had not previously been possible to realise these advantages with conventional equipment but a novel concept has emerged which solves the problems and provides additional benefits.more » All the working components of a single stream governor station are installed under a 600mm diameter surface access cover. The essential control elements are contained in a lightweight cartridge which can be exchanged in about 15 minutes by two men working from ground level.« less

Dual nature of acceptors in GaN and ZnO: The curious case of the shallow MgGa deep state

NASA Astrophysics Data System (ADS)

Lany, Stephan; Zunger, Alex

2010-04-01

Employing a Koopmans corrected density functional method, we find that the metal-site acceptors Mg, Be, and Zn in GaN and Li in ZnO bind holes in deep levels that are largely localized at single anion ligand atoms. In addition to this deep ground state (DGS), we observe an effective-masslike delocalized state that can exist as a short lived shallow transient state (STS). The Mg dopant in GaN represents the unique case where the ionization energy of the localized deep level exceeds only slightly that of the shallow effective-mass acceptor, which explains why Mg works so exceptionally well as an acceptor dopant.

Impact melt breccias at the Apollo 17 landing site

NASA Technical Reports Server (NTRS)

Ryder, Graham

1992-01-01

Impact melt breccias are by far the most common highland rock type collected on the Apollo 17 mission. They tend to be fine grained, with virtually no clast-free impact melt rocks having been identified. All the highland boulders sampled are impact melt breccia, with the possible exception of one South Massif boulder that might have a friable matrix (but nonetheless consists dominantly of impact melt) and a shocked igneous norite boulder from the North Massif. The impact melt breccias were originally described as metaclastic, but their melt origin became apparent as work progressed. Chemical compositions appear to allow natural groupings of the impact melt breccias. Various groupings of the impact melt breccias are discussed.

8 CFR 251.1 - Arrival manifests and lists.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) The prevailing practice exception for automated vessels; and (E) The reciprocity exception. (iii) If... under the reciprocity exception, the master or agent shall note on the manifest that the work will be done under the reciprocity exception, and will note the nationality of the vessel's registry and the...

8 CFR 251.1 - Arrival manifests and lists.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) The prevailing practice exception for automated vessels; and (E) The reciprocity exception. (iii) If... under the reciprocity exception, the master or agent shall note on the manifest that the work will be done under the reciprocity exception, and will note the nationality of the vessel's registry and the...

8 CFR 251.1 - Arrival manifests and lists.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) The prevailing practice exception for automated vessels; and (E) The reciprocity exception. (iii) If... under the reciprocity exception, the master or agent shall note on the manifest that the work will be done under the reciprocity exception, and will note the nationality of the vessel's registry and the...

8 CFR 251.1 - Arrival manifests and lists.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) The prevailing practice exception for automated vessels; and (E) The reciprocity exception. (iii) If... under the reciprocity exception, the master or agent shall note on the manifest that the work will be done under the reciprocity exception, and will note the nationality of the vessel's registry and the...

8 CFR 251.1 - Arrival manifests and lists.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) The prevailing practice exception for automated vessels; and (E) The reciprocity exception. (iii) If... under the reciprocity exception, the master or agent shall note on the manifest that the work will be done under the reciprocity exception, and will note the nationality of the vessel's registry and the...

8 CFR 258.2 - Exceptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... longshore work at any United States port under the exceptions provided for in paragraphs (a)(2), (b), or (c... hazardous dry bulk cargo. (i) All tankers qualify for the hazardous cargo exception, including parcel tankers, except for a tanker that has been gas-freed to transport non-hazardous dry bulk commodities. (ii...

Defining the origins of electron transfer at screen-printed graphene-like and graphite electrodes: MoO2 nanowire fabrication on edge plane sites reveals electrochemical insights.

PubMed

Rowley-Neale, Samuel J; Brownson, Dale A C; Banks, Craig E

2016-08-18

Molybdenum (di)oxide (MoO2) nanowires are fabricated onto graphene-like and graphite screen-printed electrodes (SPEs) for the first time, revealing crucial insights into the electrochemical properties of carbon/graphitic based materials. Distinctive patterns observed in the electrochemical process of nanowire decoration show that electron transfer occurs predominantly on edge plane sites when utilising SPEs fabricated/comprised of graphitic materials. Nanowire fabrication along the edge plane sites (and on edge plane like-sites/defects) of graphene/graphite is confirmed with Cyclic Voltammetry, Scanning Electron Microscopy (SEM) and Raman Spectroscopy. Comparison of the heterogeneous electron transfer (HET) rate constants (k°) at unmodified and nanowire coated SPEs show a reduction in the electrochemical reactivity of SPEs when the edge plane sites are effectively blocked/coated with MoO2. Throughout the process, the basal plane sites of the graphene/graphite electrodes remain relatively uncovered; except when the available edge plane sites have been utilised, in which case MoO2 deposition grows from the edge sites covering the entire surface of the electrode. This work clearly illustrates the distinct electron transfer properties of edge and basal plane sites on graphitic materials, indicating favourable electrochemical reactivity at the edge planes in contrast to limited reactivity at the basal plane sites. In addition to providing fundamental insights into the electron transfer properties of graphite and graphene-like SPEs, the reported simple, scalable, and cost effective formation of unique and intriguing MoO2 nanowires realised herein is of significant interest for use in both academic and commercial applications.

Center variation in the use of nonstandardized model for end-stage liver disease exception points.

PubMed

Goldberg, David S; Makar, George; Bittermann, Therese; French, Benjamin

2013-12-01

The Model for End-Stage Liver Disease (MELD) score is an imperfect prognosticator of waitlist dropout, so transplant centers may apply for exception points to increase a waitlist candidate's priority on the waitlist. Exception applications are categorized as recognized exceptional diagnoses (REDs; eg, hepatocellular carcinoma) and non-REDs (eg, cholangitis). Although prior work has demonstrated regional variation in the use of exceptions, no work has examined the between-center variability. We analyzed all new waitlist candidates from February 27, 2002 to June 3, 2011 to explore variations in the use of non-REDs, for which no strict exception criteria exist. There were 58,641 new waitlist candidates, and 4356 (7.4%) applied for a non-RED exception. The number of applications increased steadily over time, as did the approval rates for such applications: from <50% in 2002 to nearly 75% in 2010. When we adjusted for patient factors, there was significant variability (P < 0.001) in the use of non-RED exceptions in 8 of 11 United Network for Organ Sharing (UNOS) regions and in the approval of these exceptions in 6 of 11 UNOS regions. The variability in the use and approval of non-REDs was clinically significant: waitlist candidates with approved exceptions were significantly more likely to undergo transplantation (68.3% versus 53.4%, P < 0.001) and were less likely to be removed for death or clinical deterioration (10.4% versus 16.2%, P < 0.001). Increased median MELD score at transplantation within a donor service area was the only center factor associated with increased odds of applying for exceptions, while no center factors were associated with having non-RED exceptions approved. Further work is needed to identify other sources of variation to ensure the appropriate and equitable use of non-RED exceptions. © 2013 American Association for the Study of Liver Diseases.

36 CFR 3.8 - What vessel operations are prohibited?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., except at a launch site designated by the superintendent. (3) Operating a power-driven vessel on waters... power-driven or sailing vessel within 100 feet of a diver's flag except a vessel in support of dive... paragraph. (5) Unless a designated area is marked otherwise, operating a power-driven or sailing vessel...

32 CFR 644.88 - Other acquisition.

Code of Federal Regulations, 2013 CFR

2013-07-01

... for the temporary (five years) use of land (except public domain for Air Force) and buildings. The use... if a site is selected for construction and/or there is a continuing military use. Except in time of... is issued. (i) If use the of land is needed promptly to meet a construction deadline or for other use...

Life Cycle Project Plan Outline: Web Sites and Web-based Applications

EPA Pesticide Factsheets

This tool is a guideline for planning and checking for 508 compliance on web sites and web based applications. Determine which EIT components are covered or excepted, which 508 standards and requirements apply, and how to implement them.

Global Plate Velocities from the Global Positioning System

NASA Technical Reports Server (NTRS)

Larson, Kristine M.; Freymueller, Jeffrey T.; Philipsen, Steven

1997-01-01

We have analyzed 204 days of Global Positioning System (GPS) data from the global GPS network spanning January 1991 through March 1996. On the basis of these GPS coordinate solutions, we have estimated velocities for 38 sites, mostly located on the interiors of the Africa, Antarctica, Australia, Eurasia, Nazca, North America, Pacific, and South America plates. The uncertainties of the horizontal velocity components range from 1.2 to 5.0 mm/yr. With the exception of sites on the Pacific and Nazca plates, the GPS velocities agree with absolute plate model predictions within 95% confidence. For most of the sites in North America, Antarctica, and Eurasia, the agreement is better than 2 mm/yr. We find no persuasive evidence for significant vertical motions (less than 3 standard deviations), except at four sites. Three of these four were sites constrained to geodetic reference frame velocities. The GPS velocities were then used to estimate angular velocities for eight tectonic plates. Absolute angular velocities derived from the GPS data agree with the no net rotation (NNR) NUVEL-1A model within 95% confidence except for the Pacific plate. Our pole of rotation for the Pacific plate lies 11.5 deg west of the NNR NUVEL-1A pole, with an angular speed 10% faster. Our relative angular velocities agree with NUVEL-1A except for some involving the Pacific plate. While our Pacific-North America angular velocity differs significantly from NUVEL-1A, our model and NUVEL-1A predict very small differences in relative motion along the Pacific-North America plate boundary itself. Our Pacific-Australia and Pacific- Eurasia angular velocities are significantly faster than NUVEL-1A, predicting more rapid convergence at these two plate boundaries. Along the East Pacific Pise, our Pacific-Nazca angular velocity agrees in both rate and azimuth with NUVFL-1A.

Assessment and evaluation of engineering options at a low-level radioactive waste storage site

NASA Astrophysics Data System (ADS)

Kanehiro, B. Y.; Guvanasen, V.

1982-09-01

Solutions to hydrologic and geotechnical problems associated with existing disposal sites were sought and the efficiency of engineering options that were proposed to improve the integrity of such sites were evaluated. The Weldon Spring site is generally like other low-level nuclear waste sites, except that the wastes are primarily in the form of residues and contaminated rubble from the processing of uranium and thorium ores rather than industrial isotopes or mill tailings.

End-user perspectives on e-commerce and health care web site quality.

PubMed

Le Rouge, Cynthia; De Leo, Gianluca

2008-11-06

We explore and compare the importance of various quality dimensions for health care and e-commerce web sites. The results show that the importance of various quality attributes for all except four of ten quality dimensions studied differ between health care and e-commerce web sites. These results can help health care managers to improve and/or to guide the design of their web sites.

Report: Improvements Needed to Ensure EPA Terminates Exceptions to Biweekly Pay Limits at Completion of Emergency Response Work

EPA Pesticide Factsheets

Report #15-P-0170, June 19, 2015. EPA made payments totaling $4,141 to employees in excess of biweekly pay limits because authorized exceptions were not terminated at the end of emergency response work.

Kiln emissions and potters' exposures.

PubMed

Hirtle, B; Teschke, K; van Netten, C; Brauer, M

1998-10-01

Some ten thousand British Columbia potters work in small private studios, cooperative facilities, educational institutions, or recreation centers. There has been considerable concern that this diffuse, largely unregulated activity may involve exposures to unacceptable levels of kiln emissions. Pottery kiln emissions were measured at 50 sites--10 from each of 5 categories: professional studios, recreation centers, elementary schools, secondary schools, and colleges. Area monitoring was done 76 cm from firing kilns and 1.6 m above the floor to assess breathing zone concentrations of nitrogen dioxide, carbon monoxide, sulfur dioxide, fluorides, aldehydes, aluminum, antimony, arsenic, barium, beryllium, boron, cadmium, chromium, cobalt, copper, gold, iron, lead, lithium, magnesium, manganese, mercury, nickel, selenium, silver, vanadium, and zinc. Personal exposures to the same metals were measured at 24 sites. Almost all measured values were well below permissible concentrations for British Columbia work sites and American Conference of Governmental Industrial Hygienists (ACGIH) threshold limit values (TLVs) with the following two exceptions. A single firing duration (495 minute) acrolein measurement adjacent to an electric kiln (0.109 ppm) exceeded these guidelines. One 15-minute sulfur dioxide measurement collected adjacent to a gas kiln (5.7 ppm) exceeded the ACGIH short-term exposure limit. The fact that concentrations in small, ventilated kiln rooms ranked among the highest measured gives rise to concern that unacceptable levels of contamination may exist where small kiln rooms remain unventilated. Custom designed exhaust hoods and industrial heating, ventilating, and air-conditioning systems were the most effective ventilation strategies. Passive diffusion and wall/window fans were least effective.

Unified phenology model with Bayesian calibration for several European species in Belgium

NASA Astrophysics Data System (ADS)

Fu, Y. S. H.; Demarée, G.; Hamdi, R.; Deckmyn, A.; Deckmyn, G.; Janssens, I. A.

2009-04-01

Plant phenology is a good bio-indicator for climate change, and this has brought a significant increase of interest. Many kinds of phenology models have been developed to analyze and predict the phenological response to climate change, and those models have been summarized into one kind of unified model, which could be applied to different species and environments. In our study, we selected seven European woody plant species (Betula verrucosa, Quercus robur pedunculata, Fagus sylvatica, Fraxinus excelsior, Symphoricarpus racemosus, Aesculus hippocastanum, Robinia pseudoacacia) occurring in five sites distributed across Belgium. For those sites and tree species, phenological observations such as bud burst were available for the period 1956 - 2002. We also obtained regional downscaled climatic data for each of these sites, and combined both data sets to test the unified model. We used a Bayesian approach to generate distributions of model parameters from the observation data. In this poster presentation, we compare parameter distributions between different species and between different sites for individual species. The results of the unified model show a good agreement with the observations, except for Fagus sylvatica. The failure to reproduce the bud burst data for Fagus sylvatica suggest that the other factors not included in the unified model affect the phenology of this species. The parameter series show differences among species as we expected. However, they also differed strongly for the same species among sites.Further work should elucidate the mechanism that explains why model parameters differ among species and sites.

Comparison of atmospheric mercury speciation and deposition at nine sites across central and eastern North America

USGS Publications Warehouse

Engle, Mark A.; Tate, Michael T.; Krabbenhoft, David P.; Schauer, James J; Kolker, Allan; Shanley, James B.; Bothner, Michael

2010-01-01

was observed but was highly dependant upon inclusion of data from two sites with exceptionally high deposition. Findings from this study highlight the importance of environmental setting on atmospheric Hg cycling and deposition rates.

MICROBIAL ECOLOGY OF THE SUBSURFACE AT AN ABANDONED CREOSOTE WASTE SITE

EPA Science Inventory

The microbial ecology of pristine, slightly contaminated, and heavily contaminated subsurface materials, and four subsurface materials on the periphery of the plume at an abandoned creosote waste site was investigated. Except for the unsaturated zone of the heavily contaminated m...

Report: Independent Ground Water Sampling Generally Confirms EPA’s Data at Wheeler Pit Superfund Site in Wisconsin

EPA Pesticide Factsheets

Report #10-P-0218, September 8, 2010. With minimal exceptions, our independent sampling results at the Wheeler Pit Superfund Site were consistent with the sampling results that EPA Region 5 has obtained historically.

40 CFR 1400.10 - Limitation on public dissemination.

Code of Federal Regulations, 2011 CFR

2011-07-01

... SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Other Provisions § 1400.10 Limitation on public dissemination. Except as... officials, and qualified researchers are prohibited from disseminating OCA information and OCA rankings to...

40 CFR 1400.10 - Limitation on public dissemination.

Code of Federal Regulations, 2012 CFR

2012-07-01

... SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Other Provisions § 1400.10 Limitation on public dissemination. Except as... officials, and qualified researchers are prohibited from disseminating OCA information and OCA rankings to...

40 CFR 1400.10 - Limitation on public dissemination.

Code of Federal Regulations, 2014 CFR

2014-07-01

... SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Other Provisions § 1400.10 Limitation on public dissemination. Except as... officials, and qualified researchers are prohibited from disseminating OCA information and OCA rankings to...

40 CFR 1400.10 - Limitation on public dissemination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS INFORMATION Other Provisions § 1400.10 Limitation on public dissemination. Except as... officials, and qualified researchers are prohibited from disseminating OCA information and OCA rankings to...

49 CFR 325.33 - Site characteristics; highway operations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Section 325.33 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.33 Site... or utility poles. (2) Rural mailboxes. (3) Traffic railings of any type of construction except solid...

49 CFR 325.33 - Site characteristics; highway operations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 325.33 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.33 Site... or utility poles. (2) Rural mailboxes. (3) Traffic railings of any type of construction except solid...

49 CFR 325.33 - Site characteristics; highway operations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Section 325.33 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.33 Site... or utility poles. (2) Rural mailboxes. (3) Traffic railings of any type of construction except solid...

49 CFR 325.33 - Site characteristics; highway operations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 325.33 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR... MOTOR CARRIER NOISE EMISSION STANDARDS Measurement of Noise Emissions; Highway Operations § 325.33 Site... or utility poles. (2) Rural mailboxes. (3) Traffic railings of any type of construction except solid...

Typology and credibility of Internet health websites originating from Gulf Cooperation Council countries.

PubMed

Weber, A S; Verjee, M; Rahman, Z H; Ameerudeen, F; Al-Baz, N

2015-02-02

The quality of information available on health websites in the Gulf Cooperation Council (GCC) countries has not been comprehensively assessed. From November to December 2012 we retrieved all functional health-related websites (n = 925) originating in GCC countries. Data on authorship, language, date, information content and type of site were recorded. A novel website checklist was developed based on the credibility and trust criteria of the Internet assessment organization Health On the Net Foundation (HON). Only 5 sites (0.5%) fulfilled all checklist categories. All websites except one were in English or Arabic languages. Only 10.1% of websites posted a privacy policy, 2.7% stated the authorship of information, 51.0% disclosed website ownership, 80.6% provided contact details and 58.5% dated information. Only 1.7% reported their advertising policy and 23.5% revealed sponsorships. GCC health website owners should consider working with the HON or similar organizations to meet internationally recognized credibility criteria.

Anti-site disorder and improved functionality of Mn₂NiX (X = Al, Ga, In, Sn) inverse Heusler alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paul, Souvik; Kundu, Ashis; Ghosh, Subhradip, E-mail: subhra@iitg.ernet.in

2014-10-07

Recent first-principles calculations have predicted Mn₂NiX (X = Al, Ga, In, Sn) alloys to be magnetic shape memory alloys. Moreover, experiments on Mn₂NiGa and Mn₂NiSn suggest that the alloys deviate from the perfect inverse Heusler arrangement and that there is chemical disorder at the sublattices with tetrahedral symmetry. In this work, we investigate the effects of such chemical disorder on phase stabilities and magnetic properties using first-principles electronic structure methods. We find that except Mn₂NiAl, all other alloys show signatures of martensitic transformations in presence of anti-site disorder at the sublattices with tetrahedral symmetry. This improves the possibilities of realizingmore » martensitic transformations at relatively low fields and the possibilities of obtaining significantly large inverse magneto-caloric effects, in comparison to perfect inverse Heusler arrangement of atoms. We analyze the origin of such improvements in functional properties by investigating electronic structures and magnetic exchange interactions.« less

Coarse-Grained Molecular Simulation of Epidermal Growth Factor Receptor Protein Tyrosine Kinase Multi-Site Self-Phosphorylation

PubMed Central

Koland, John G.

2014-01-01

Upon the ligand-dependent dimerization of the epidermal growth factor receptor (EGFR), the intrinsic protein tyrosine kinase (PTK) activity of one receptor monomer is activated, and the dimeric receptor undergoes self-phosphorylation at any of eight candidate phosphorylation sites (P-sites) in either of the two C-terminal (CT) domains. While the structures of the extracellular ligand binding and intracellular PTK domains are known, that of the ∼225-amino acid CT domain is not, presumably because it is disordered. Receptor phosphorylation on CT domain P-sites is critical in signaling because of the binding of specific signaling effector molecules to individual phosphorylated P-sites. To investigate how the combination of conventional substrate recognition and the unique topological factors involved in the CT domain self-phosphorylation reaction lead to selectivity in P-site phosphorylation, we performed coarse-grained molecular simulations of the P-site/catalytic site binding reactions that precede EGFR self-phosphorylation events. Our results indicate that self-phosphorylation of the dimeric EGFR, although generally believed to occur in trans, may well occur with a similar efficiency in cis, with the P-sites of both receptor monomers being phosphorylated to a similar extent. An exception was the case of the most kinase-proximal P-site-992, the catalytic site binding of which occurred exclusively in cis via an intramolecular reaction. We discovered that the in cis interaction of P-site-992 with the catalytic site was facilitated by a cleft between the N-terminal and C-terminal lobes of the PTK domain that allows the short CT domain sequence tethering P-site-992 to the PTK core to reach the catalytic site. Our work provides several new mechanistic insights into the EGFR self-phosphorylation reaction, and demonstrates the potential of coarse-grained molecular simulation approaches for investigating the complexities of self-phosphorylation in molecules such as EGFR (HER/ErbB) family receptors and growth factor receptor PTKs in general. PMID:24453959

Monitoring of Radon in Tourist Part of Skocjan Caves

NASA Astrophysics Data System (ADS)

Debevec Gerjevic, Vanja; Jovanovic, Peter

2010-05-01

Due to their exceptional significance for cultural and natural heritage, the Škocjan Caves were entered on UNESCO's list of natural and cultural world heritage sites in 1986. Park Škocjan Caves is located in South Eastern part of Slovenia. It was established with aim of conserving and protecting exceptional geomorphological, geological and hydrological outstanding features, rare and endangered plant and animal species, paleontological and archaeological sites, ethnological and architectural characteristics and cultural landscape and for the purpose of ensuring opportunities for suitable development, by the National Assembly of the Republic of Slovenia in 1996. Park Škocjan Caves established monitoring that includes caves microclimate parameters: humidity, CO2, wind flow and radon concentration and daughter products. The approach in managing the working place with natural background radiation is complex. Monitoring of Radon has been functioning for more than ten years now. Presentation will show the yearly dynamic observed in the different parts of the caves, related to radon daughter products and other microclimatic data, beside the most convenient measuring technique. Implementing the Slovene legislation in the field of radiation protection, we are obligated to perform special measurements in the caves and also having our guides and workers in the caves regularly examined according to established procedure. The medical exams are performed at Institution of Occupational Safety, Ljubljana in order to monitor the influence of Radon to the workers in the cave. The equivalent dose for each employed person is also established on regular basis and it is part of medical survey of workers in the caves. The survey will be described along with education of the staff working in the caves in the field of radiation protection. An overview of Slovene legislation with practical example on implementation will be demonstrated in the case of Škocjan Caves where the managing authority considers the monitoring of Radon as one of the tools for adaptive management.

ABO alleles are linked with haplotypes of an erythroid cell-specific regulatory element in intron 1 with a few exceptions attributable to genetic recombination.

PubMed

Nakajima, T; Sano, R; Takahashi, Y; Watanabe, K; Kubo, R; Kobayashi, M; Takahashi, K; Takeshita, H; Kominato, Y

2016-01-01

Recent investigation of transcriptional regulation of the ABO genes has identified a candidate erythroid cell-specific regulatory element, named the +5·8-kb site, in the first intron of ABO. Six haplotypes of the site have been reported previously. The present genetic population study demonstrated that each haplotype was mostly linked with specific ABO alleles with a few exceptions, possibly as a result of hybrid formation between common ABO alleles. Thus, investigation of these haplotypes could provide a clue to further elucidation of ABO alleles. © 2015 International Society of Blood Transfusion.

78 FR 54816 - Approval and Promulgation of Implementation Plans; Oklahoma; Revisions to Excess Emissions...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... accepted only between the hours of 8:00 a.m. and 4:00 p.m. weekdays except for legal holidays. Special... otherwise protected from disclosure. The www.regulations.gov Web site is an ``anonymous access'' system... except for legal holidays. Contact the person listed in the FOR FURTHER INFORMATION CONTACT paragraph...

Toward Rational Design of Cu/SSZ-13 Selective Catalytic Reduction Catalysts: Implications from Atomic-Level Understanding of Hydrothermal Stability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, James; Wang, Yilin; Walter, Eric D.

The hydrothermal stability of Cu/SSZ-13 SCR catalysts has been extensively studied, yet atomic level understanding of changes to the zeolite support and the Cu active sites during hydrothermal aging are still lacking. In this work, via the utilization of spectroscopic methods including solid-state 27Al and 29Si NMR, EPR, DRIFTS, and XPS, together with imaging and elemental mapping using STEM, detailed kinetic analyses, and theoretical calculations with DFT, various Cu species, including two types of isolated active sites and CuOx clusters, were precisely quantified for samples hydrothermally aged under varying conditions. This quantification convincingly confirms the exceptional hydrothermal stability of isolatedmore » Cu2+-2Z sites, and the gradual conversion of [Cu(OH)]+-Z to CuOx clusters with increasing aging severity. This stability difference is rationalized from the hydrolysis activation barrier difference between the two isolated sites via DFT. Discussions are provided on the nature of the CuOx clusters, and their possible detrimental roles on catalyst stability. Finally, a few rational design principles for Cu/SSZ-13 are derived rigorously from the atomic-level understanding of this catalyst obtained here. The authors gratefully acknowledge the US Department of Energy (DOE), Energy Efficiency and Renewable Energy, Vehicle Technologies Office for the support of this work. Computing time was granted by a user proposal at the William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) and by the National Energy Research Scientific Computing Center (NERSC). The experimental studies described in this paper were performed in the EMSL, a national scientific user facility sponsored by the DOE’s Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory (PNNL). PNNL is operated for the US DOE by Battelle.« less

Standardized UXO Technology Demonstration Site Woods Scoring Record Number 636 (Blackhawk Geoservices)

DTIC Science & Technology

2005-07-01

25 SECTION 5. ON-SITE LABOR COSTS SECTION 6. COMPARISON OF RESULTS TO OPEN FIELD DEMONSTRATION 6.1 SUMMARY OF RESULTS FROM OPEN...included for the purposes of calculating labor costs (section 5) except for downtime due to Demonstration Site issues. Demonstration Site issues, while noted...in the Daily Log, are considered non-chargeable downtime for the purposes of calculating labor costs and are not discussed. Breaks and lunches are

ANIMAL INVESTIGATION PROGRAM 1978 ANNUAL REPORT: NEVADA TEST SITE AND VICINITY

EPA Science Inventory

Data are presented from the radioanalysis of tissues collected from cattle and wildlife that resided on or near the Nevada Test Site. Gamma-emitting radionuclides were detected infrequently with the exception of short-lived radionuclides found in samples from animals collected so...

Working with Navajo Parents of Exceptional Children.

ERIC Educational Resources Information Center

Jones, Doris; And Others

Undergraduate students at Northern Arizona University interviewed and surveyed 20 staff members at Kayenta Unified School District (KUSD) on the Navajo Reservation and 14 parents of exceptional Navajo children enrolled in KUSD. Both groups were asked to identify challenges affecting the working relationship between parents and school on a rural…

Prevalence of white spot syndrome virus (WSSV) in wild shrimp Penaeus monodon in the Philippines.

PubMed

de la Peña, Leobert D; Lavilla-Pitogo, Celia R; Villar, Corina Belle R; Paner, Milagros G; Sombito, Christopher D; Capulos, Geimbo C

2007-10-15

Prevalence of white spot syndrome virus (WSSV) was determined using polymerase chain reaction (PCR) methodology on DNA extracted from the gills of wild black tiger shrimp Penaeus monodon collected from 7 sampling sites in the Philippines. These 7 sampling sites are the primary sources of spawners and broodstock for hatchery use. During the dry season, WSSV was detected in shrimp from all sites except Bohol, but during the wet season it was not detected in any site except Palawan. None of the WSSV-PCR positive shrimp showed signs of white spots in the cuticle. Prevalence of WSSV showed seasonal variations, i.e. prevalence in dry season (April to May) was higher than in the wet season (August to October). These results suggest that WSSV has already become established in the local marine environment and in wild populations of P. monodon. Thus, broodstock collected during the dry season could serve as the main source of WSSV contamination in shrimp farms due to vertical transmission of the virus in hatcheries.

76 FR 19381 - Buy American Exceptions Under the American Recovery and Reinvestment Act of 2009

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-07

... Green High Rise Apartments. An exception was also granted to the Housing Authority of the City of Runge... work, using CFRFC grant funds, in connection with the Bowling Green High Rise Apartments. The exception...

Effects of Army Training Activities on Bird Communities at the Pinon Canyon Maneuver Site, Colorado

DTIC Science & Technology

1991-09-01

sparrows increased markedly over the 2 years, while the latter three declined. Mockingbirds , western kingbirds, and Brewer’s sparrows were not common...except for kingbirds, on site 37, and mockingbirds and northern orioles, on site 3. (Both of these sites contained trees.) Total and relative density... mockingbirds . The average among the eleven species with significant multiple correlations (excluding Cassin’s sparrow) was 66.8 percent. Species below the

Performance of engineered soil and trees in a parking lot bioswale

Treesearch

Qingfu Xiao; Gregory McPherson

2011-01-01

A bioswale integrating an engineered soil and trees was installed in a parking lot to evaluate its ability to reduce storm runoff, pollutant loading, and support tree growth. The adjacent control and treatment sites each received runoff from eight parking spaces and were identical except that there was no bioswale for the control site. A tree was planted at both sites...

Improving Cancer Outcomes Through International Collaboration in Academic Cancer Treatment Trials

PubMed Central

Trimble, Edward L.; Abrams, Jeffrey S.; Meyer, Ralph M.; Calvo, Fabien; Cazap, Eduardo; Deye, James; Eisenhauer, Elizabeth; Fitzgerald, Thomas J.; Lacombe, Denis; Parmar, Max; Seibel, Nita; Shankar, Lalitha; Swart, Ann Marie; Therasse, Patrick; Vikram, Bhadrasain; von Frenckell, Remy; Friedlander, Michael; Fujiwara, Keiichi; Kaplan, Richard S.; Meunier, Francoise

2009-01-01

Purpose The need for international collaboration in cancer clinical trials has grown stronger as we have made progress both in cancer treatment and screening. We sought to identify those efforts already underway which facilitate such collaboration, as well as barriers to greater collaboration. Methods We reviewed the collective experiences of many cooperative groups, governmental organizations, nongovernmental organizations, and academic investigators in their work to build international collaboration in cancer clinical trials across multiple disease sites. Results More than a decade of work has led to effective global harmonization for many of the elements critical to cancer clinical trials. Many barriers remain, but effective international collaboration in academic cancer treatment trials should become the norm, rather than the exception. Conclusion Our ability to strengthen international collaborations will result in maximization of our resources and patients, permitting us to change practice by establishing more effective therapeutic strategies. Regulatory, logistical, and financial hurdles, however, often hamper the conduct of joint trials. We must work together as a global community to overcome these barriers so that we may continue to improve cancer treatment for patients around the world. PMID:19720905

Stress induced by heavy metals on breeding of magpie (Pica pica) from central Iran.

PubMed

Zarrintab, Mohammad; Mirzaei, Rouhollah

2017-09-01

The aim of this study was to address the impacts of some heavy metals (Cd, Pb, Zn, Ni and Cu) contamination on laying behavior, egg quality and breeding performance of Pica pica in north of Isfahan Province, Iran. During the breeding season of 2013, magpie's egg content and eggshell as well as nestling excrements and feathers were collected and total concentrations of heavy metals were measured by ICP-OES. Except for Zn in nestling feathers, the significantly higher concentrations of heavy metals were observed in nestling excrements than other samples. Also, comparison of heavy metals concentrations in egg content and eggshell showed that egg content had significantly higher concentrations of Zn and Pb, instead eggshell had significantly higher amount of Cu and Cd. Except for Cu, all heavy metals concentrations in eggshell had a negative relationship with morphological characters; and also concentration of Cu in egg content showed a significantly negative correlation with egg weight and volume. The most of heavy metals in nestling feathers and excrements had strongly positive correlations with each other. Also all heavy metals levels in eggshell and egg content had significantly positive correlations (except for Cu). Unhatched eggs had significantly lower weight but also greater levels of Zn, Cd, and Pb, than randomly collected eggs. No significant differences were observed for morphometric measurements of eggs between different sites, however, a decreased gradient was observed in egg volume toward the brick kiln site. Samples collected in brick kiln site accumulated higher concentrations of heavy metals than other sites. Although numbers of clutch size in brick kiln site were significantly higher than other sites, however, other breeding variable were lower than other sites. It can be suggested that ecosystem contamination may be caused to decrease the reproduction rate of Pica pica in brick kiln, probably by laying more poor quality eggs per clutch and nestling mortality. Copyright © 2017 Elsevier Inc. All rights reserved.

A simplified gross primary production and evapotranspiration model for boreal coniferous forests - is a generic calibration sufficient?

NASA Astrophysics Data System (ADS)

Minunno, F.; Peltoniemi, M.; Launiainen, S.; Aurela, M.; Lindroth, A.; Lohila, A.; Mammarella, I.; Minkkinen, K.; Mäkelä, A.

2015-07-01

The problem of model complexity has been lively debated in environmental sciences as well as in the forest modelling community. Simple models are less input demanding and their calibration involves a lower number of parameters, but they might be suitable only at local scale. In this work we calibrated a simplified ecosystem process model (PRELES) to data from multiple sites and we tested if PRELES can be used at regional scale to estimate the carbon and water fluxes of Boreal conifer forests. We compared a multi-site (M-S) with site-specific (S-S) calibrations. Model calibrations and evaluations were carried out by the means of the Bayesian method; Bayesian calibration (BC) and Bayesian model comparison (BMC) were used to quantify the uncertainty in model parameters and model structure. To evaluate model performances BMC results were combined with more classical analysis of model-data mismatch (M-DM). Evapotranspiration (ET) and gross primary production (GPP) measurements collected in 10 sites of Finland and Sweden were used in the study. Calibration results showed that similar estimates were obtained for the parameters at which model outputs are most sensitive. No significant differences were encountered in the predictions of the multi-site and site-specific versions of PRELES with exception of a site with agricultural history (Alkkia). Although PRELES predicted GPP better than evapotranspiration, we concluded that the model can be reliably used at regional scale to simulate carbon and water fluxes of Boreal forests. Our analyses underlined also the importance of using long and carefully collected flux datasets in model calibration. In fact, even a single site can provide model calibrations that can be applied at a wider spatial scale, since it covers a wide range of variability in climatic conditions.

Empires, Exceptions, and Anglo-Saxons: Race and Rule between the British and Unites States Empires, 1880-1910. Teaching the JAH.

ERIC Educational Resources Information Center

OAH Magazine of History, 2002

2002-01-01

Summarizes a teaching document that is part of "Teaching the JAH" (Journal of American History) which corresponds to the article, "Empires, Exceptions, and Anglo-Saxons: Race and Rule between the British and Unites States Empires, 1880-1910" (Paul A. Kramer). Provides the Web site address for the complete installment. (CMK)

International VLBI Service for Geodesy and Astrometry 2013 Annual Report

NASA Technical Reports Server (NTRS)

Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.

2014-01-01

This volume of reports is the 2013 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2013 Annual Report documents the work of the IVS components for the calendar year 2013, our fifteenth year of existence. The reports describe changes, activities, and progress of the IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and the last section, the contents of this Annual Report also appear on the IVS Web site at http://ivscc.gsfc.nasa.gov/publications/ar2013.

International VLBI Service for Geodesy and Astrometry 2012 Annual Report

NASA Technical Reports Server (NTRS)

Baver, Karen D.; Behrend, Dirk; Armstrong, Kyla L.

2013-01-01

This volume of reports is the 2012 Annual Report of the International VLBI Service for Geodesy and Astrometry (IVS). The individual reports were contributed by VLBI groups in the international geodetic and astrometric community who constitute the permanent components of IVS. The IVS 2012 Annual Report documents the work of the IVS components for the calendar year 2012, our fourteenth year of existence. The reports describe changes, activities, and progress ofthe IVS. Many thanks to all IVS components who contributed to this Annual Report. With the exception of the first section and parts of the last section (described below), the contents of this Annual Report also appear on the IVS Web site athttp:ivscc.gsfc.nasa.gov/publications/ar2012

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

20 CFR 655.510 - Employer attestations.

Code of Federal Regulations, 2013 CFR

2013-04-01

... practice after Secretary of State determination of non-reciprocity. Section 258(d) of the Act provides a reciprocity exception (separate from the prevailing practice exception) to the prohibition on performance of longshore work by alien crewmembers in U.S. ports. However, this reciprocity exception becomes nonapplicable...

5 CFR 2411.4 - Information policy.

Code of Federal Regulations, 2011 CFR

2011-01-01

... instructions to staff that affect a member of the public (except those establishing internal operating rules... the Internet/World Wide-Web site (http://www.flra.gov/foia/reading_room.html). The Web site containing... Reading Room should be submitted to the FLRA's Office of the Solicitor (mail: Office of the Solicitor...

37 CFR 360.12 - Form and content of claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... site at http://www.loc.gov/crb/satellite/ during the month of July for claims filed online in... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.12 - Form and content of claims.

Code of Federal Regulations, 2014 CFR

2014-07-01

... site at http://www.loc.gov/crb/satellite/ during the month of July for claims filed online in... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.12 - Form and content of claims.

Code of Federal Regulations, 2013 CFR

2013-07-01

... site at http://www.loc.gov/crb/satellite/ during the month of July for claims filed online in... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.12 - Form and content of claims.

Code of Federal Regulations, 2012 CFR

2012-07-01

... site at http://www.loc.gov/crb/satellite/ during the month of July for claims filed online in... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.12 - Form and content of claims.

Code of Federal Regulations, 2011 CFR

2011-07-01

... site at http://www.loc.gov/crb/satellite/ during the month of July for claims filed online in... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

Euk-mPLoc: a fusion classifier for large-scale eukaryotic protein subcellular location prediction by incorporating multiple sites.

PubMed

Chou, Kuo-Chen; Shen, Hong-Bin

2007-05-01

One of the critical challenges in predicting protein subcellular localization is how to deal with the case of multiple location sites. Unfortunately, so far, no efforts have been made in this regard except for the one focused on the proteins in budding yeast only. For most existing predictors, the multiple-site proteins are either excluded from consideration or assumed even not existing. Actually, proteins may simultaneously exist at, or move between, two or more different subcellular locations. For instance, according to the Swiss-Prot database (version 50.7, released 19-Sept-2006), among the 33,925 eukaryotic protein entries that have experimentally observed subcellular location annotations, 2715 have multiple location sites, meaning about 8% bearing the multiplex feature. Proteins with multiple locations or dynamic feature of this kind are particularly interesting because they may have some very special biological functions intriguing to investigators in both basic research and drug discovery. Meanwhile, according to the same Swiss-Prot database, the number of total eukaryotic protein entries (except those annotated with "fragment" or those with less than 50 amino acids) is 90,909, meaning a gap of (90,909-33,925) = 56,984 entries for which no knowledge is available about their subcellular locations. Although one can use the computational approach to predict the desired information for the blank, so far, all the existing methods for predicting eukaryotic protein subcellular localization are limited in the case of single location site only. To overcome such a barrier, a new ensemble classifier, named Euk-mPLoc, was developed that can be used to deal with the case of multiple location sites as well. Euk-mPLoc is freely accessible to the public as a Web server at http://202.120.37.186/bioinf/euk-multi. Meanwhile, to support the people working in the relevant areas, Euk-mPLoc has been used to identify all eukaryotic protein entries in the Swiss-Prot database that do not have subcellular location annotations or are annotated as being uncertain. The large-scale results thus obtained have been deposited at the same Web site via a downloadable file prepared with Microsoft Excel and named "Tab_Euk-mPLoc.xls". Furthermore, to include new entries of eukaryotic proteins and reflect the continuous development of Euk-mPLoc in both the coverage scope and prediction accuracy, we will timely update the downloadable file as well as the predictor, and keep users informed by publishing a short note in the Journal and making an announcement in the Web Page.

Testing Nine Archaeological Sites in the Downstream Corridor, Saylorville Lake, Iowa. 1982.

DTIC Science & Technology

1983-04-01

cultivated field (fallow since 1981), covering an area of approximately 2 acres . The site is bordered on the west by the river bank and on the north by...sites in the project area. What Middle Archaic period sites in alluvial contexts are likely to yield is an unanswered question at this time, but it is ...13PK410 and 13PK413 be preserved in place, except for minor construction on 13PK413. Site 13PK407, an Oneota occupation, is recommended either for

OTEC platform configuration and integration study. Volume I. Systems engineering and integration. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1978-04-01

The economic success of an Ocean Thermal Energy Conversion (OTEC) system is highly dependent on a platform which provides adequate support for the power system, accommodates reliably the cold water pipe, and is most cost effective. The results of a study conducted for the Department of Energy to assess six generic types of platforms to determine the most satisfactory platform for severl potential sites are presented. The six platform configurations are ship, circular barge, semi-submersible, Tuned Sphere, submersible, and spar. These represent directional and symmetric types of platforms which operate on the surface, at the interface, and submerged. The fivemore » sites for this study were primarily New Orleans, Keahole Point (Hawaii), Brazil, and secondarily Key West and Puerto Rico. Electrical transmission of energy by submarine cable is the planned form of energy transmission for all sites except Brazil, where chemical conversion is to be the method of transmission. This study is devoted to the platform (or ocean systems) of the OTEC plant which is chiefly comprised of the hull and structure, the seawater system, the position control system, and miscellaneous support/assembly systems. The principal elements in the work breakdown structure for the commercial plants are presented. The assessment of the six platform configurations was conducted utilizing a baseline plan (100-MW(e) (Net)) and site (New Orleans) with variations from the baseline to cover the range of interested platforms and sites.« less

How One Exceptional Teacher Navigated Her Working Environment as the Teacher of a Marginal Subject

ERIC Educational Resources Information Center

Lux, Karen; McCullick, Bryan A.

2011-01-01

The purpose of this study was to analyze how one exceptional elementary physical education teacher navigated her working environment as the teacher of a marginal subject. Structuration Theory (Giddens, 1984) was used to make meaning of how the teacher functioned within her school community allowing her to remain motivated and effective. Data…

Chapter 13: Interannual Differences in Detections of Marbled Murrelets in Some Inland California Stands

Treesearch

C. John Ralph

1995-01-01

I compared the mean level of detections of Marbled Murrelets by month over five years at three inland sites in northern California. These areas all have relatively high levels of detections. There were no significant differences in mean detection levels year to year at any site, and for any month with the exception of April at one site. This lack of evidence for...

Genomic profiling of multiple sequentially acquired tumor metastatic sites from an “exceptional responder” lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response

PubMed Central

Biswas, Romi; Gao, Shaojian; Cultraro, Constance M.; Maity, Tapan K.; Venugopalan, Abhilash; Abdullaev, Zied; Shaytan, Alexey K.; Carter, Corey A.; Thomas, Anish; Rajan, Arun; Song, Young; Pitts, Stephanie; Chen, Kevin; Bass, Sara; Boland, Joseph; Hanada, Ken-Ichi; Chen, Jinqiu; Meltzer, Paul S.; Panchenko, Anna R.; Yang, James C.; Pack, Svetlana; Giaccone, Giuseppe; Schrump, David S.; Khan, Javed; Guha, Udayan

2016-01-01

We used next-generation sequencing to identify somatic alterations in multiple metastatic sites from an “exceptional responder” lung adenocarcinoma patient during his 7-yr course of ERBB2-directed therapies. The degree of heterogeneity was unprecedented, with ∼1% similarity between somatic alterations of the lung and lymph nodes. One novel translocation, PLAG1-ACTA2, present in both sites, up-regulated ACTA2 expression. ERBB2, the predominant driver oncogene, was amplified in both sites, more pronounced in the lung, and harbored an L869R mutation in the lymph node. Functional studies showed increased proliferation, migration, metastasis, and resistance to ERBB2-directed therapy because of L869R mutation and increased migration because of ACTA2 overexpression. Within the lung, a nonfunctional CDK12, due to a novel G879V mutation, correlated with down-regulation of DNA damage response genes, causing genomic instability, and sensitivity to chemotherapy. We propose a model whereby a subclone metastasized early from the primary site and evolved independently in lymph nodes. PMID:27900369

Base-flow measurements at partial-record sites on small streams in South Carolina

USGS Publications Warehouse

Barker, Carroll

1986-01-01

This report contains site descriptions and base-flow data collected at 362 partial-record sites in South Carolina. These data include site name, site description, latitude, longitude, drainage area, instantaneous streamflow, and date of the streamflow measurement. The base-flow data can be used as an aid to estimate low flow characteristics at ungaged locations on streams in South Carolina. Partial record data collection sites were established in all physiographic provinces except the lower Coastal Plain. Data collection sites were not established in the lower Coastal Plain because of the widespread occurrence of zero during drought periods in all but the larger streams. (USGS)

Exceptional Asian Children and Youth. An ERIC Exceptional Child Education Report.

ERIC Educational Resources Information Center

Kitano, Margie K., Ed.; Chinn, Philip C., Ed.

Intended as a means of sharing information with educators and other professionals who work with exceptional Asian American children and families, the monograph includes six papers growing out of a symposium and addressing issues related to demographics, characteristics and needs, parents and families, assessment, and curriculum and service…

An inventory of terrestrial mammals at national parks in the Northeast Temperate Network and Sagamore Hill National Historic Site

USGS Publications Warehouse

Gilbert, Andrew T.; O'Connell, Allan F.; Annand, Elizabeth M.; Talancy, Neil W.; Sauer, John R.; Nichols, James D.

2008-01-01

An inventory of mammals was conducted during 2004 at nine national park sites in the Northeast Temperate Network (NETN): Acadia National Park (NP), Marsh-Billings-Rockefeller National Historical Park (NHP), Minute Man NHP, Morristown NHP, Roosevelt-Vanderbilt National Historic Site (NHS), Saint-Gaudens NHS, Saugus Iron Works NHS, Saratoga NHP, and Weir Farm NHS. Sagamore Hill NHS, part of the Northeast Coastal and Barrier Network (NCBN), was also surveyed. Each park except Acadia NP was sampled twice, once in the winter/spring and again in the summer/fall. During the winter/spring visit, indirect measure (IM) sampling arrays were employed at 2 to 16 stations and included sampling by remote cameras, cubby boxes (covered trackplates), and hair traps. IM stations were established and re-used during the summer/fall sampling period. Trapping was conducted at 2 to 12 stations at all parks except Acadia NP during the summer/fall period and consisted of arrays of small-mammal traps, squirrel-sized live traps, and some fox-sized live traps. We used estimation-based procedures and probabilistic sampling techniques to design this inventory. A total of 38 species was detected by IM sampling, trapping, and field observations. Species diversity (number of species) varied among parks, ranging from 8 to 24, with Minute Man NHP having the most species detected. Raccoon (Procyon lotor), Virginia Opossum (Didelphis virginiana), Fisher (Martes pennanti), and Domestic Cat (Felis silvestris) were the most common medium-sized mammals detected in this study and White-footed Mouse (Peromyscus leucopus), Northern Short-tailed Shrew (Blarina brevicauda), Deer Mouse (P. maniculatus), and Meadow Vole (Microtus pennsylvanicus) the most common small mammals detected. All species detected are considered fairly common throughout their range including the Fisher, which has been reintroduced in several New England states. We did not detect any state or federal endangered or threatened species.

CREB, NF-Y and MEIS1 conserved binding sites are essential to balance Myostatin promoter/enhancer activity during early myogenesis.

PubMed

Grade, Carla Vermeulen Carvalho; Mantovani, Carolina Stefano; Fontoura, Marina Alves; Yusuf, Faisal; Brand-Saberi, Beate; Alvares, Lúcia Elvira

2017-10-01

Myostatin (MSTN) is a strong inhibitor of skeletal muscle growth in human and other vertebrates. Its transcription is controlled by a proximal promoter/enhancer (Mstn P/E) containing a TATA box besides CREB, NF-Y, MEIS1 and FXR transcription factor binding sites (TFBSs), which are conserved throughout evolution. The aim of this work was to investigate the role of these TFBSs on Mstn P/E activity and evaluate the potential of their putative ligands as Mstn trans regulators. Mstn P/E mutant constructs were used to establish the role of conserved TFBSs using dual-luciferase assays. Expression analyses were performed by RT-PCR and in situ hybridization in C2C12 myoblasts and E10.5 mouse embryos, respectively. Our results revealed that CREB, NF-Y and MEIS1 sites are required to balance Mstn P/E activity, keeping Mstn transcription within basal levels during myoblast proliferation. Furthermore, our data showed that NF-Y site is essential, although not sufficient, to mediate Mstn P/E transcriptional activity. In turn, CREB and MEIS1 binding sites seem to depend on the presence of NF-Y site to induce Mstn P/E. FXR appears not to confer any effect on Mstn P/E activity, except in the absence of all other conserved TFBS. Accordingly, expression studies pointed to CREB, NF-Y and MEIS1 but not to FXR factors as possible regulators of Mstn transcription in the myogenic context. Altogether, our findings indicated that CREB, NF-Y and MEIS1 conserved sites are essential to control basal Mstn transcription during early myogenesis, possibly by interacting with these or other related factors.

Evaluation of Cobas Integra 800 under simulated routine conditions in six laboratories.

PubMed

Redondo, Francisco L; Bermudez, Pilar; Cocco, Claudio; Colella, Francesca; Graziani, Maria Stella; Fiehn, Walter; Hierla, Thomas; Lemoël, Gisèle; Belliard, AnneMarie; Manene, Dieudonne; Meziani, Mourad; Liebel, Maryann; McQueen, Matthew J; Stockmann, Wolfgang

2003-03-01

The new selective access analyser Cobas Integra 800 from Roche Diagnostics was evaluated in an international multicentre study at six sites. Routine simulation experiments showed good performance and full functionality of the instrument and provocation of anomalous situations generated no problems. The new features on Cobas Integra 800, namely clot detection and dispensing control, worked according to specifications. The imprecision of Cobas Integra 800 fulfilled the proposed quality specifications regarding imprecision of analytical systems for clinical chemistry with few exceptions. Claims for linearity, drift, and carry-over were all within the defined specifications, except urea linearity. Interference exists in some cases, as could be expected due to the chemistries applied. Accuracy met the proposed quality specifications, except in some special cases. Method comparisons with Cobas Integra 700 showed good agreement; comparisons with other analysis systems yielded in several cases explicable deviations. Practicability of Cobas Integra 800 met or exceeded the requirements for more than 95% of all attributes rated. The strong points of the new analysis system were reagent handling, long stability of calibration curves, high number of tests on board, compatibility of the sample carrier to other Roche systems, and the sample integrity check for more reliable analytical results. The improvement of the workflow offered by the 5-position rack and STAT handling like on Cobas Integra 800 makes the instrument attractive for further consolidation in the medium-sized laboratory, for dedicated use of special analytes, and/or as back-up in the large routine laboratory.

43 CFR 2094.2 - Waiver of 160-rod limitation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... necessary for harborage, landing, and wharf purposes. The act does not authorize the waiver of the 80-rod restriction, mentioned in § 2094.0-3. (b) Except as to trade and manufacturing sites, and home and headquarters sites, any applications to enter and notices of settlement which cover lands extending more than...

36 CFR 7.22 - Grand Teton National Park.

Code of Federal Regulations, 2010 CFR

2010-07-01

... a notice of any change of fees. (x) All livestock are considered as mature animals at six months of... sites within the Park. (2) Except in group campsites and backcountry sites, camping is limited to six... private lands in the Craighead Subdivision. (ii) The unplowed portion of the Teton Park Road to the piece...

Multiply Degenerate Exceptional Points and Quantum Phase Transitions

NASA Astrophysics Data System (ADS)

Borisov, Denis I.; Ružička, František; Znojil, Miloslav

2015-12-01

The realization of a genuine phase transition in quantum mechanics requires that at least one of the Kato's exceptional-point parameters becomes real. A new family of finite-dimensional and time-parametrized quantum-lattice models with such a property is proposed and studied. All of them exhibit, at a real exceptional-point time t = 0, the Jordan-block spectral degeneracy structure of some of their observables sampled by Hamiltonian H( t) and site-position Q( t). The passes through the critical instant t = 0 are interpreted as schematic simulations of non-equivalent versions of the Big-Bang-like quantum catastrophes.

Exceptional Family Transitional Training Program (EFTTP)

DTIC Science & Technology

2009-01-01

relationship with Reading for the Blind and Dyslexic® (RFBD), EPGL will be offering recordings for the visually impaired on its Web site in 2009. Experts...EPGL Web site. Stories have included information regarding new Department of Veterans Affairs (VA) rules for housing grants that aid the most seriously...EP also added a special Military Channel to its Web site. The channel provides links to important resources available to military families in a one

Expressive Therapies, the ARTS and the Exceptional Child. (An Annotated Bibliography).

ERIC Educational Resources Information Center

Minar, Virginia, Comp.; And Others

The annotated bibliography lists approximately 500 citations (1967-1978) regarding the arts and exceptional children in preschool through grade 8. It is explained that the bibliography was designed to provide concrete material and ideas for teachers and therapists working with exceptional children in mainstreamed, resource room, or special class…

Investigating the Factors of Resiliency among Exceptional Youth Living in Rural Underserved Communities

ERIC Educational Resources Information Center

Curtin, Kevin A.; Schweitzer, Ashley; Tuxbury, Kristen; D'Aoust, Janelle A.

2016-01-01

Resilience is an important social justice concept that has important implications for educators working with exceptional youth in rural underserved communities who may suffer from the consequences associated with economic hardships. This multi-school qualitative study examined resilience among exceptional youth living in rural poverty through the…

10 CFR 26.207 - Waivers and exceptions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Waivers and exceptions. 26.207 Section 26.207 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.207 Waivers and exceptions. (a) Waivers. Licensees may grant a waiver of one or more of the work hour controls in § 26.205(d)(1...

10 CFR 26.207 - Waivers and exceptions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Waivers and exceptions. 26.207 Section 26.207 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.207 Waivers and exceptions. (a) Waivers. Licensees may grant a waiver of one or more of the work hour controls in § 26.205(d)(1...

10 CFR 26.207 - Waivers and exceptions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Waivers and exceptions. 26.207 Section 26.207 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.207 Waivers and exceptions. (a) Waivers. Licensees may grant a waiver of one or more of the work hour controls in § 26.205(d)(1...

10 CFR 26.207 - Waivers and exceptions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Waivers and exceptions. 26.207 Section 26.207 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.207 Waivers and exceptions. (a) Waivers. Licensees may grant a waiver of the work hour controls in § 26.205(d)(1) through (d)(5...

10 CFR 26.207 - Waivers and exceptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Waivers and exceptions. 26.207 Section 26.207 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Managing Fatigue § 26.207 Waivers and exceptions. (a) Waivers. Licensees may grant a waiver of the work hour controls in § 26.205(d)(1) through (d)(5...

Recruiting Research Participants at Community Education Sites

PubMed Central

SADLER, GEORGIA ROBINS; PETERSON, MELANIE; WASSERMAN, LINDA; MILLS, PAUL L.; MALCARNE, VANESSA L.; ROCK, CHERYL; ANCOLI-ISRAEL, SONIA; MOORE, AMANDA; WELDON, RAI-NESHA; GARCIA, TENISHA; KOLODNER, RICHARD D.

2006-01-01

Background Minority groups are underrepresented in research, making it difficult to apply medical advances with confidence. In this study, we explored whether community-based cancer education sites and educators serving the African American community could be used to recruit minority participants to research. Methods We invited Individuals at community education sites to provide buccal scrapings, saliva samples, psychometric data, and personal information anonymously. Results Culturally aligned community sites (100%) collaborated in the research recruitment, as did 83% of the individuals at those sites. Conclusion Community-based education sites offer exceptional promise for teaching about research benefits and recruiting members of minority groups to research studies. PMID:16497136

28 CFR 63.9 - Exception.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential to save lives and protect property and public health and safety performed pursuant to sections 305 and 306...

Study of pulmonary functions of the tourist guides in two show caves in Slovenia

NASA Astrophysics Data System (ADS)

Debevec Gerjevic, V.; Jovanovič, P.

2009-04-01

Park Škocjan Caves is located in South Eastern part of Slovenia. It was established with aim of conserving and protecting exceptional geomorphological, geological and hydrological outstanding features, rare and endangered plant and animal species, paleontological and archaeological sites, ethnological and architectural characteristics and cultural landscape and for the purpose of ensuring opportunities for suitable development, by the National Assembly of the Republic of Slovenia in 1996. Due to their exceptional significance for cultural and natural heritage, the Škocjan Caves were entered on UNESCO's list of natural and cultural world heritage sites in 1986. Caves have always been special places for people all over the world. There has been a lot of research done in the field of speleology and also in medicine in relation to speleotherapy. There is still one field left partial unexplored and its main issue covers the interaction between special ecosystems as caves and human activities and living. Implementing the Slovene legislation in the field of radiation protection, we are obligated to perform special measurements in the caves and also having our guides and workers in the caves regularly examined according to established procedure. The medical exams are performed at Institution of Occupational Safety, Ljubljana in order to monitor the influence of Radon to the workers in the cave. The issue of epidemiologic research encompass several factors that are not necessarily related to the radon. Park Škocjan Caves established research monitoring projects such as caves microclimate parameters, quality of the water, every day's data from our meteorological station useful tool in public awareness related to pollution and climate change. Last year a special study was started in order to evaluate pulmonary functions of persons who work in the caves and those who work mostly in offices. Two groups of tourist guides from Škocjan Caves and Postojna Cave were included in the study. The promising results will highlight the need of medical survey of people working in the caves and help managers of the caves to adopt reactive management process. In order to facilitate decision process related to protection of people and caves environment, special recommendation in form of index of environment's use will be proposed after the study.

Combining experimental techniques with non-linear numerical models to assess the sorption of pesticides on soils

NASA Astrophysics Data System (ADS)

Magga, Zoi; Tzovolou, Dimitra N.; Theodoropoulou, Maria A.; Tsakiroglou, Christos D.

2012-03-01

The risk assessment of groundwater pollution by pesticides may be based on pesticide sorption and biodegradation kinetic parameters estimated with inverse modeling of datasets from either batch or continuous flow soil column experiments. In the present work, a chemical non-equilibrium and non-linear 2-site sorption model is incorporated into solute transport models to invert the datasets of batch and soil column experiments, and estimate the kinetic sorption parameters for two pesticides: N-phosphonomethyl glycine (glyphosate) and 2,4-dichlorophenoxy-acetic acid (2,4-D). When coupling the 2-site sorption model with the 2-region transport model, except of the kinetic sorption parameters, the soil column datasets enable us to estimate the mass-transfer coefficients associated with solute diffusion between mobile and immobile regions. In order to improve the reliability of models and kinetic parameter values, a stepwise strategy that combines batch and continuous flow tests with adequate true-to-the mechanism analytical of numerical models, and decouples the kinetics of purely reactive steps of sorption from physical mass-transfer processes is required.

A THz Superconducting Imaging Array Developed for the DATE5 Telescope

NASA Astrophysics Data System (ADS)

Shi, Sheng-Cai; Zhang, Wen; Li, Jing; Miao, Wei; Lin, Zhen-Hui; Lou, Zheng; Yao, Qi-Jun

2016-08-01

Dome A in Antarctica, located at an altitude of 4093 m and with very low temperature in winter down to -83^{circ }C, is an exceptionally dry site. Measurements of the atmospheric transmission in the range of 0.75-15 THz by a Far-infrared/THz Fourier transform spectrometer (FTS) strongly suggest that Dome A is a unique site for ground-based THz observations, especially for the 200- and 350-micron windows. A 5-m THz telescope (DATE5) is therefore proposed for Chinese Antarctic Kunlun Observatory. We are currently developing a THz superconducting imaging array (TeSIA) for the DATE5. The TeSIA will be working at the 350-\\upmu m window, with a pixel number of 32 × 32 and a sensitivity (NEP) of ˜ 10^{-16} W/Hz^{0.5}. Ti transition-edge sensors with time-domain multiplexing and TiN microwave kinetic inductance detectors with frequency-domain multiplexing are both developed for the TeSIA. In this paper, detailed system designs and some measurement results will be presented.

Pollutant loading from low-density residential neighborhoods in California.

PubMed

Bale, Andrew E; Greco, Steven E; Pitton, Bruno J L; Haver, Darren L; Oki, Lorence R

2017-08-01

This paper presents a comparison of pollutant load estimations for runoff from two geographically distinct residential suburban neighborhoods in northern and southern California. The two neighborhoods represent a single urban land use type: low-density residential in small catchments (<0.3 km 2 ) under differing regional climates and irrigation practices. Pollutant loads of pesticides, nutrients, and drinking water constituents of concern are estimated for both storm and non-storm runoff. From continuous flow monitoring, it was found that a daily cycle of persistent runoff that peaks mid-morning occurs at both sites. These load estimations indicate that many residential neighborhoods in California produce significant non-storm pollutant loads year-round. Results suggest that non-storm flow accounted for 47-69% of total annual runoff and significantly contributed to annual loading rates of most nutrients and pesticides at both sites. At the Southern California site, annual non-storm loads are 1.2-10 times higher than storm loads of all conventional constituents and nutrients with one exception (total suspended solids). At the Northern California site, annual storm loads range from 51 to 76% of total loads for all conventional constituents and nutrients with one exception (total dissolved solids). Non-storm yields of pesticides at the Southern California site range from 1.3-65 times higher than those at the Northern California site. The disparity in estimated pollutant loads between the two sites indicates large potential variation from site-to-site within the state and suggests neighborhoods in drier and milder climates may produce significantly larger non-storm loads due to persistent dry season runoff and year-round pest control.

Adaptive evolution of the STRA6 genes in mammalian.

PubMed

Wu, Jianghong; Xiang, Hui; Qi, Yunxia; Yang, Ding; Wang, Xiaojuan; Sun, Hailian; Wang, Feng; Liu, Bin

2014-01-01

Stimulated by retinoic acid 6 (STRA6) is the receptor for retinol binding protein and is relevant for the transport of retinol to specific sites such as the eye. The adaptive evolution mechanism that vertebrates have occupied nearly every habitat available on earth and adopted various lifestyles associated with different light conditions and visual challenges, as well as their role in development and adaptation is thus far unknown. In this work, we have investigated different aspects of vertebrate STRA6 evolution and used molecular evolutionary analyses to detect evidence of vertebrate adaptation to the lightless habitat. Free-ratio model revealed significant rate shifts immediately after the species divergence. The amino acid sites detected to be under positive selection are within the extracellular loops of STRA6 protein. Branch-site model A test revealed that STRA6 has undergone positive selection in the different phyla of mammalian except for the branch of rodent. The results suggest that interactions between different light environments and host may be driving adaptive change in STRA6 by competition between species. In support of this, we found that altered functional constraints may take place at some amino acid residues after speciation. We suggest that STRA6 has undergone adaptive evolution in different branch of vertebrate relation to habitat environment.

The QSAR and docking calculations of fullerene derivatives as HIV-1 protease inhibitors

NASA Astrophysics Data System (ADS)

Saleh, Noha A.

2015-02-01

The inhibition of HIV-1 protease is considered as one of the most important targets for drug design and the deactivation of HIV-1. In the present work, the fullerene surface (C60) is modified by adding oxygen atoms as well as hydroxymethylcarbonyl (HMC) groups to form 6 investigated fullerene derivative compounds. These compounds have one, two, three, four or five O atoms + HMC groups at different positions on phenyl ring. The effect of the repeating of these groups on the ability of suggested compounds to inhibit the HIV protease is studied by calculating both Quantitative Structure Activity Relationship (QSAR) properties and docking simulation. Based on the QSAR descriptors, the solubility and the hydrophilicity of studied fullerene derivatives increased with increasing the number of oxygen atoms + HMC groups in the compound. While docking calculations indicate that, the compound with two oxygen atoms + HMC groups could interact and binds with HIV-1 protease active site. This is could be attributed to the active site residues of HIV-1 protease are hydrophobic except the two aspartic acids. So that, the increase in the hydrophilicity and polarity of the compound is preventing and/or decreasing the hydrophobic interaction between the compound and HIV-1 protease active site.

The major hurricanes of 2005: A few facts: Chapter 2B in Science and the storms-the USGS response to the hurricanes of 2005

USGS Publications Warehouse

Farris, Gaye S.

2007-01-01

The following is a compilation of storm terminology, categories, and names as well as the meteorological history, damage, and paths of Hurricanes Dennis, Katrina, Rita, and Wilma. This information is taken, except where noted, from the Web site and archives of the National Hurricane Center (NHC), a part of the National Oceanic and Atmospheric Administration's National Weather Service (NWS). Greater details are available at www.nhc.noaa.gov. These facts are presented here to provide the reader background for the articles in this volume describing the storm science of the U.S. Geological Survey, which works with the NWS during hurricanes by providing real-time river stage data used by NWS to forecast river floods.

Nanoscale microstructure effects on hydrogen behavior in rapidly solidified aluminum alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tashlykova-Bushkevich, Iya I.

2015-12-31

The present work summarizes recent progress in the investigation of nanoscale microstructure effects on hydrogen behavior in rapidly solidified aluminum alloys foils produced at exceptionally high cooling rates. We focus here on the potential of modification of hydrogen desorption kinetics in respect to weak and strong trapping sites that could serve as hydrogen sinks in Al materials. It is shown that it is important to elucidate the surface microstructure of the Al alloy foils at the submicrometer scale because rapidly solidified microstructural features affect hydrogen trapping at nanostructured defects. We discuss the profound influence of solute atoms on hydrogen−lattice defectmore » interactions in the alloys. with emphasis on role of vacancies in hydrogen evolution; both rapidly solidified pure Al and conventionally processed aluminum samples are considered.« less

Trivalent ions modification for high-silica mordenite: A first principles study

NASA Astrophysics Data System (ADS)

Chen, Fayun; Zhang, Laijun; Feng, Gang; Wang, Xuewen; Zhang, Rongbin; Liu, Jianwen

2018-03-01

Using periodic DFT-D3-U methods, the present work give a mechanistic insight into the high silica B-, Al-, Ga- and Fe-MOR with H, Li, Na, and K as charge balance ions. The acid properties of the zeolite were probed via NH3 and pyridine adsorption. It is found that the charge balance ions influence the location of the trivalent ions, the cell volumes, as well as the synthesis difficulty of the zeolites. The energy differences for B, Al, Ga and Fe in different T sites are small for the H-form zeolites, while large for the Na- and K-form zeolites. For H-form MOR, the proton of the sbnd OH group prefers to bond to O(7) and O(3) and pointing to the 12MR for trivalent ions in T1 sites. The proton bonds to O(3), O(2), O(2) and O(5), respectively, for B, Al, Ga and Fe in T2 site of MOR, with the sbnd OH group pointing to intersection of 12MR and the side-pocket, except for the B-MOR that sbnd OH group pointing to the 12MR. For trivalent ions located in T3 and T4 sites, the protons prefers to bond to O(1) and O(2), respectively, with the sbnd OH group pointing to the intersection of 8MR and side-pocket as well as the intersection of 12MR and side-pocket. All incorporated B, Al, Ga, and Fe framework ions are tetra-coordinated, except the B atoms are tri-coordinated. The NH4-form MOR has smaller cell volume than the other form MOR. Na and K are energetically more favored charge balance ions than Li and NH3 for MOR zeolites synthesis, and the H-form zeolite is the most difficult to be synthesized directly. The strength of the Brønsted acidity follows the order: HBMOR < HFeMOR ≈ HGaMOR < HAlMOR, vs. the Lewis acidity order: HBMOR < HAlMOR < HFeMOR ≈ HGaMOR. NH3 could be adsorbed inside all kinds of channels, and especially favors in the small 8MR vs. pyridine could only be adsorbed in the main channel of MOR due to the steric effect. It indicates that the acid sites in the side pocket and the small 8-membered ring and the side pocket could not be effectively determined just by the pyridine adsorption experiments. In comparison, the NH3 adsorption experiments could detect all kinds of Brønsted sites of the MOR zeolites.

The mobility gap between older men and women: the embodiment of gender.

PubMed

Zunzunegui, M V; Alvarado, B E; Guerra, R; Gómez, J F; Ylli, A; Guralnik, J M

2015-01-01

To present the study design and baseline results of the longitudinal International Mobility in Aging Study (IMIAS) on gender differences in physical performance and mobility disability prevalence in five diverse societies. Data are from surveys on random samples of people aged 65-74 years at Canadian (Kingston, Ontario; Saint-Hyacinthe, Quebec), Mediterranean (Tirana, Albania) and Latin American sites (Natal, Brazil; Manizales, Colombia) (N=1995). Mobility disability was defined as reporting difficulty in walking 400m or climbing stairs. Activities of daily living (ADL) disability was based on any self-reported difficulty in five mobility-related ADLs. The short physical performance battery (SPPB) was used to assess physical performance. Poisson regression models were fitted to estimate prevalence ratios. Age-adjusted prevalence of low SPPB, mobility disability and ADL disability were higher in women than in men in all sites except for Kingston. After adjustment for education and income, gender differences in SPPB and ADL disability attenuated or disappeared in Saint-Hyacinthe and Manizales but remained large in Tirana and Natal and mobility disability remained more frequent in women than in men at all sites except Kingston. After further adjustment by chronic conditions and depressive symptoms, gender differences in mobility remained large at all sites except Kingston but only in Tirana did women have significantly poorer physical performance than men. Results provide evidence for gender as a risk factor to explain poorer physical function in women and suggest that moving toward gender equality could attenuate the gender gap in physical function in old age. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

32 CFR 263.6 - Speeding or reckless driving.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., weather, and road surface and having regard to the actual and potential hazards existing. (b) Except when a special hazard exists that requires lower speed, the speed limit on the site is 15 m.p.h., unless another speed limit has been duly posted, and no person shall drive a motor vehicle on the site in excess...

32 CFR 263.6 - Speeding or reckless driving.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., weather, and road surface and having regard to the actual and potential hazards existing. (b) Except when a special hazard exists that requires lower speed, the speed limit on the site is 15 m.p.h., unless another speed limit has been duly posted, and no person shall drive a motor vehicle on the site in excess...

32 CFR 263.6 - Speeding or reckless driving.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., weather, and road surface and having regard to the actual and potential hazards existing. (b) Except when a special hazard exists that requires lower speed, the speed limit on the site is 15 m.p.h., unless another speed limit has been duly posted, and no person shall drive a motor vehicle on the site in excess...

32 CFR 263.6 - Speeding or reckless driving.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., weather, and road surface and having regard to the actual and potential hazards existing. (b) Except when a special hazard exists that requires lower speed, the speed limit on the site is 15 m.p.h., unless another speed limit has been duly posted, and no person shall drive a motor vehicle on the site in excess...

32 CFR 263.6 - Speeding or reckless driving.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., weather, and road surface and having regard to the actual and potential hazards existing. (b) Except when a special hazard exists that requires lower speed, the speed limit on the site is 15 m.p.h., unless another speed limit has been duly posted, and no person shall drive a motor vehicle on the site in excess...

76 FR 28821 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... exclusively through computer software-based models or applications termed under the rule as ``interactive Web... conducted through an interactive Web site in accordance with the rule.\\7\\ \\1\\ 17 CFR 275.203A-2(f). Included in rule 203A-2(f) is a limited exception to the interactive Web site requirement which allows these...

34 CFR 600.20 - Notice and application procedures for establishing, reestablishing, maintaining, or expanding...

Code of Federal Regulations, 2013 CFR

2013-07-01

... hospitals or clinics providing all or a portion of a clinical training program required under § 600.55(e)(1... are located, including all sites at which its students receive clinical training, except those clinical training sites that are not used regularly, but instead are chosen by individual students who take...

34 CFR 600.20 - Notice and application procedures for establishing, reestablishing, maintaining, or expanding...

Code of Federal Regulations, 2014 CFR

2014-07-01

... hospitals or clinics providing all or a portion of a clinical training program required under § 600.55(e)(1... are located, including all sites at which its students receive clinical training, except those clinical training sites that are not used regularly, but instead are chosen by individual students who take...

34 CFR 600.20 - Notice and application procedures for establishing, reestablishing, maintaining, or expanding...

Code of Federal Regulations, 2012 CFR

2012-07-01

... hospitals or clinics providing all or a portion of a clinical training program required under § 600.55(e)(1... are located, including all sites at which its students receive clinical training, except those clinical training sites that are not used regularly, but instead are chosen by individual students who take...

15 CFR 265.43 - Pets and other animals.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Pets and other animals. 265.43 Section... animals. Except in connection with the conduct of official business on the site or with the approval of... person shall bring upon the site any cat, dog, or other animal, provided, however, that blind persons may...

15 CFR 265.43 - Pets and other animals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Pets and other animals. 265.43 Section... animals. Except in connection with the conduct of official business on the site or with the approval of... person shall bring upon the site any cat, dog, or other animal, provided, however, that blind persons may...

15 CFR 265.43 - Pets and other animals.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Pets and other animals. 265.43 Section... animals. Except in connection with the conduct of official business on the site or with the approval of... person shall bring upon the site any cat, dog, or other animal, provided, however, that blind persons may...

15 CFR 265.43 - Pets and other animals.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Pets and other animals. 265.43 Section... animals. Except in connection with the conduct of official business on the site or with the approval of... person shall bring upon the site any cat, dog, or other animal, provided, however, that blind persons may...

15 CFR 265.43 - Pets and other animals.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Pets and other animals. 265.43 Section... animals. Except in connection with the conduct of official business on the site or with the approval of... person shall bring upon the site any cat, dog, or other animal, provided, however, that blind persons may...

Pretest information for a test to validate plume simulation procedures (FA-17)

NASA Technical Reports Server (NTRS)

Hair, L. M.

1978-01-01

The results of an effort to plan a final verification wind tunnel test to validate the recommended correlation parameters and application techniques were presented. The test planning effort was complete except for test site finalization and the associated coordination. Two suitable test sites were identified. Desired test conditions were shown. Subsequent sections of this report present the selected model and test site, instrumentation of this model, planned test operations, and some concluding remarks.

Selected water-soluble organic compounds found in size-resolved aerosols collected from urban, mountain and marine atmospheres over East Asia

NASA Astrophysics Data System (ADS)

Wang, Gehui; Kawamura, Kimitaka; Xie, Mingjie; Hu, Shuyuan; Li, Jianjun; Zhou, Bianhong; Cao, Junji; An, Zhisheng

2011-07-01

Primary (i.e. sugars and sugar-alcohols) and secondary (i.e. carboxylic acids) water-soluble organic compounds (WSOCs) in size-segregated aerosols from the urban and mountain atmosphere of China and from the marine atmosphere in the outflow region of East Asia were characterized on a molecular level. Levoglucosan is the most abundant compound among the quantified WSOCs in the urban and mountain atmosphere, whose concentration at the urban site was 1-2 orders of magnitude higher than that at the mountain and marine sites. In contrast, malic, succinic and phthalic acids were dominant among the measured WSOCs at the marine site. In the urban air, sugars except levoglucosan gave a bimodal size distribution with a large peak in fine range (<2.1 μm) and a small peak in coarse range (≥2.1 μm) during winter, being opposite to those in spring. In contrast, these WSOCs at the mountain and marine sites dominated in the coarse range but diminished and even disappeared in the fine range. Geometric mean diameters (GMDs) of the measured WSOCs in the fine mode at the urban site were larger in winter than in spring. Levoglucosan and carboxylic acids except for azelaic and benzoic acids showed a larger GMD in the coarse mode at the marine site probably due to an increased hygroscopic growth.

Idaho National Laboratory Site Pollution Prevention Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

E. D. Sellers

2007-03-01

It is the policy of the Department of Energy (DOE) that pollution prevention and sustainable environmental stewardship will be integrated into DOE operations as a good business practice to reduce environmental hazards, protect environmental resources, avoid pollution control costs, and improve operational efficiency and mission sustainability. In furtherance of this policy, DOE established five strategic, performance-based Pollution Prevention (P2) and Sustainable Environmental Stewardship goals and included them as an attachment to DOE O 450.1, Environmental Protection Program. These goals and accompanying strategies are to be implemented by DOE sites through the integration of Pollution Prevention into each site's Environmental Managementmore » System (EMS). This document presents a P2 and Sustainability Program and corresponding plan pursuant to DOE Order 450.1 and DOE O 435.1, Radioactive Waste Management. This plan is also required by the state of Idaho, pursuant to the Resource Conservation and Recovery Act (RCRA) partial permit. The objective of this document is to describe the Idaho National Laboratory (INL) Site P2 and Sustainability Program. The purpose of the program is to decrease the environmental footprint of the INL Site while providing enhanced support of its mission. The success of the program is dependent on financial and management support. The signatures on the previous page indicate INL, ICP, and AMWTP Contractor management support and dedication to the program. P2 requirements have been integrated into working procedures to ensure an effective EMS as part of an Integrated Safety Management System (ISMS). This plan focuses on programmatic functions which include environmentally preferable procurement, sustainable design, P2 and Sustainability awareness, waste generation and reduction, source reduction and recycling, energy management, and pollution prevention opportunity assessments. The INL Site P2 and Sustainability Program is administratively managed by the INL Site P2 Coordinator. Development and maintenance of this overall INL Site plan is ultimately the responsibility of DOE-ID. This plan is applicable to all INL Site contractors except those at the Naval Reactors Facility.« less

Gender, health, and human rights in sites of political exclusion.

PubMed

Laurie, M; Petchesky, R P

2008-01-01

In this paper, we investigate the intersections of gender, health and human rights in sites of political exclusion. We apply the political theory of Giorgio Agamben on 'states of exception', seeking to better understand how the recent 'war on terror', that seemingly knows no limits of time or space, is driving health outcomes in refugee and Internally Displaced Persons (IDP) camps. Reproductive health, militarization, and gender-based violence in camps are explored in depth. The evidence presented reveals a number of contradictions of refugee and IDP camps, further highlighting the need for a more rights based humanitarianism. We conclude that foregrounding states of exception, as a way of understanding current gender dynamics in the social determinants of health, is both epidemiologically necessary and conceptually useful. We find that, in these sites of exclusion, the indispensability of a human rights approach to gender and health equity issues is revealed most directly. Furthermore, we are able to make new connections between the 'crisis of humanitarianism', gender, and health.

Characterization of Conserved Tandem Donor Sites and Intronic Motifs Required for Alternative Splicing in Corticosteroid Receptor Genes

PubMed Central

Qian, Xiaoxiao; Matthews, Laura; Lightman, Stafford; Ray, David; Norman, Michael

2015-01-01

Alternative splicing events from tandem donor sites result in mRNA variants coding for additional amino acids in the DNA binding domain of both the glucocorticoid (GR) and mineralocorticoid (MR) receptors. We now show that expression of both splice variants is extensively conserved in mammalian species, providing strong evidence for their functional significance. An exception to the conservation of the MR tandem splice site (an A at position +5 of the MR+12 donor site in the mouse) was predicted to decrease U1 small nuclear RNA binding. In accord with this prediction, we were unable to detect the MR+12 variant in this species. The one exception to the conservation of the GR tandem splice site, an A at position +3 of the platypus GRγ donor site that was predicted to enhance binding of U1 snRNA, was unexpectedly associated with decreased expression of the variant from the endogenous gene as well as a minigene. An intronic pyrimidine motif present in both GR and MR genes was found to be critical for usage of the downstream donor site, and overexpression of TIA1/TIAL1 RNA binding proteins, which are known to bind such motifs, led to a marked increase in the proportion of GRγ and MR+12. These results provide striking evidence for conservation of a complex splicing mechanism that involves processes other than stochastic spliceosome binding and identify a mechanism that would allow regulation of variant expression. PMID:19819975

The Snowmastodon Project

USGS Publications Warehouse

Johnson, Kirk R.; Miller, Ian M.; Pigati, Jeffery S.

2014-01-01

Studies of terrestrial biotic and environmental dynamics of the last interglacial period, Marine Oxygen Isotope Stage (MIS) 5, provide insight into the effects of long-term climate change on Pleistocene ecosystems. In North America, however, there are relatively few fossil sites that definitively date to MIS 5. Even fewer contain multiple ecosystem components (vertebrates, invertebrates, plants) that have been studied in detail, and none are located at high elevation. Thus, our view of North American ecosystems during MIS 5 is, at best, an incomplete composite view, and alpine ecosystems are entirely undocumented. The Ziegler Reservoir fossil site allows us to begin filling these gaps. Discovered on October 14, 2010 by a construction crew while enlarging a small reservoir near Snowmass Village, Colorado (USA), the site is situated high in the Rocky Mountains at an elevation of ~ 2705 m. Initial excavations exposed a series of stacked fossil ecosystems, including abundant faunal and floral components. Subsequent work revealed an exceptionally diverse biota composed of nearly 6000 large bones of late Pleistocene megafauna, including mastodons, mammoths, ground sloths, horses, camels, deer, bison, black bear, coyotes, and big horn sheep. This collection is complemented by more than 200 bones from at least 40 species of small animals including otters, muskrats, minks, rabbits, beavers, frogs, lizards, snakes, fish, and birds, and more than 20,000 salamander bones. Geomorphic evidence and multiple dating techniques show that the small, ridge-top basin containing the site was formed by a lateral lobe of a valley glacier that filled, and ultimately overtopped, the Snowmass Creek drainage during the Bull Lake glaciation (MIS 6). When the glacier receded, a lake that occupied the basin began to fill slowly with what is hypothesized to be eolian sediment and occasional input from slope failures of the impounding moraine. As sedimentation continued, the lake transformed first into a shallow pond, then a marsh, and later an alpine meadow. In all, the Ziegler Reservoir sedimentary record spans the time encompassed by the end of MIS 6, all of MIS 5 and MIS 4, and the earliest part of MIS 3. MIS 5e, which is considered to be the peak warmth of the last interglacial period, is especially well represented. Preservation of organic material at the Ziegler Reservoir fossil site is exceptional. Even after more than 100,000 years of burial, sedge and willow leaves were still green, mollusks and gastropods showed color, beetle parts remained iridescent, fossil conifer cones were intact, and an entire beach of 20-meter-long driftwood logs was found intact. The exquisite preservation allowed for detailed analysis of pollen, plant macrofossils, conifer cones, and fossil wood, as well as insects, chironomids, mollusks, ostracodes, and other invertebrates — all in addition to the spectacular faunal remains. This special volume of Quaternary Research represents a comprehensive scientific report of “The Snowmastodon Project,” as the investigations at the Ziegler Reservoir fossil site came to be known. Summarizing the work of scientists from more than 20 institutions, the volume details the environments in which the animals lived, provides insight into how they died, and forms the foundation of our understanding of alpine ecosystem dynamics during the last interglacial period in the Rocky Mountains.

9 CFR 130.18 - User fees for veterinary diagnostic reagents produced at NVSL or other authorized site (excluding...

Code of Federal Regulations, 2013 CFR

2013-01-01

.... 1, 2011 Antigen, except avian influenza and chlamydia psittaci antigens, any 2 mL $61.00 $62.00 $64.00 $65.00 $67.00 Avian antiserum except avian influenza antiserum, any 2 mL 48.00 49.00 51.00 52.00 53.00 Avian influenza antigen, any 2 mL 33.00 34.00 35.00 36.00 36.00 Avian influenza antiserum, any...

9 CFR 130.18 - User fees for veterinary diagnostic reagents produced at NVSL or other authorized site (excluding...

Code of Federal Regulations, 2012 CFR

2012-01-01

.... 1, 2011 Antigen, except avian influenza and chlamydia psittaci antigens, any 2 mL $61.00 $62.00 $64.00 $65.00 $67.00 Avian antiserum except avian influenza antiserum, any 2 mL 48.00 49.00 51.00 52.00 53.00 Avian influenza antigen, any 2 mL 33.00 34.00 35.00 36.00 36.00 Avian influenza antiserum, any...

9 CFR 130.18 - User fees for veterinary diagnostic reagents produced at NVSL or other authorized site (excluding...

Code of Federal Regulations, 2014 CFR

2014-01-01

.... 1, 2011 Antigen, except avian influenza and chlamydia psittaci antigens, any 2 mL $61.00 $62.00 $64.00 $65.00 $67.00 Avian antiserum except avian influenza antiserum, any 2 mL 48.00 49.00 51.00 52.00 53.00 Avian influenza antigen, any 2 mL 33.00 34.00 35.00 36.00 36.00 Avian influenza antiserum, any...

Land Use Withdrawal, McGregor Range, Fort Bliss, Texas

DTIC Science & Technology

1977-08-01

Range by armoured vehicles to existing maneuver areas south of McGregor Range Camp. j. Cease joint training exercises requiring the use of the basin...Maneuvers: Site Avoidance a. Implement all measures called for in Alternative 1 except i. and j., restriction of armoured vehicle use. b. Define...Maneuvers. District Avcidance a. Implement all measures called for in Alternative 1 except i. and j. restriction of armoured vehicle use. b. Define

Does the Police-Monitored CCTV Scheme Really Matter on Crime Reduction? A Quasi-Experimental Test in Taiwan's Taipei City.

PubMed

Lai, Yung-Lien; Sheu, Chuen-Jim; Lu, Yi-Fen

2018-06-01

Although numerous public closed-circuit television (CCTV) initiatives have been implemented at varying levels in Taiwan's cities and counties, systematic evaluations of these crime reduction efforts have been largely overlooked. To address this void, a quasi-experimental evaluation research project was designed to assess the effect of police-monitored CCTV on crime reduction in Taipei City for a period of 54 months, including data for both before and after camera installation dates. A total of 40 viewsheds within a 100-m (328 feet) radius were selected as research sites to observe variations in four types of crime incidents that became known to police during the January 2008 to June 2012 period. While crime incidents occurring in both the target and control sites were reduced in frequency after CCTV installation, results derived from time-series analysis indicated that the monitoring had no significant effect on the reduction of property crime incidents with the sole exception of robbery. With respect to the effects of comparing target and control sites, the average Crime Reduction Quotient (CRQ) was 0.36, suggesting that CCTV has an overall marginal yet noteworthy influence. Viewed broadly, however, the police-installed CCTV system in Taipei City did not appear to be as efficient as one would expect. Conversely, cameras installed in some observation sites proved to be significantly more effective than cameras in other sites. As a recommendation, future researchers should identify how particular micro-level attributes may lead to CCTV cameras working more effectively, thereby optimizing location choices where monitoring will prove to be most productive.

7 CFR 205.406 - Continuation of certification.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT...-site inspection of the certified operation pursuant to § 205.403: Except, That, when it is impossible...

7 CFR 205.406 - Continuation of certification.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT...-site inspection of the certified operation pursuant to § 205.403: Except, That, when it is impossible...

7 CFR 205.406 - Continuation of certification.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT...-site inspection of the certified operation pursuant to § 205.403: Except, That, when it is impossible...

7 CFR 205.406 - Continuation of certification.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT...-site inspection of the certified operation pursuant to § 205.403: Except, That, when it is impossible...

40 CFR 52.2476 - Discretionary authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... authority. (a) This section applies to any variance, exception, exemption, alternative emission limitation... Department of Ecology, the Department of Natural Resources, the Energy Facility Site Evaluation Council, or a...

Fire Effects on Greenhouse Gas Emissions from Wetlands in the Yukon-Kuskokwim Delta, Alaska

NASA Astrophysics Data System (ADS)

Peter, D. L.; Bristol, E. M.; Mann, P. J.; Schade, J. D.; Natali, S.; Holmes, R. M.

2017-12-01

Climate change in increasing both fire frequency and fire intensity, especially in Arctic regions. Fire often leads to increased soil temperature, which increases the likelihood of permafrost thaw. Permafrost soils in northern latitudes store large amounts of carbon, and thawing of this permafrost will alter carbon cycling processes, which may substantially impact ecosystem processes in aquatic ecosystems. One potential consequence of altered aquatic ecosystem processes is changes in carbon emissions resulting from altered carbon inputs from thawing permafrost. Aquatic ecosystems are known to be hotspots of greenhouse gas emissions, so changes in greenhouse gas fluxes from them may have important impacts on global climate. In this work, we focused on CO2 and CH4 fluxes from peat plateau ponds, fens and bogs in the Yukon-Kuskokwim (YK) Delta in southwest Alaska. The YK Delta experienced unprecedented fires in summer 2015, presenting an opportunity to assess the impacts of fire on greenhouse gas fluxes from aquatic ecosystems. We sampled upland ponds, channel fens, bogs, and lowland ponds in sites that had burned in 2015 as well as from similar sites where there have been no recorded fires in the past 75 years. We found little difference in gas flux between aquatic sites in burned and unburned sites, with the exception of channel fens, which showed substantially higher fluxes of both CH4 and CO2 in burned sites. This is in contrast to similar measurements taken in summer 2016, when burned ponds showed consistently higher GHG fluxes, suggesting these increases were not sustained in sites other than channel fens. These results, if general, indicate the possibility that the response of aquatic ecosystems to fire may lead to positive feedbacks on climate change.

Export production in the New-Zealand region since the Last Glacial Maximum

NASA Astrophysics Data System (ADS)

Durand, Axel; Chase, Zanna; Noble, Taryn L.; Bostock, Helen; Jaccard, Samuel L.; Kitchener, Priya; Townsend, Ashley T.; Jansen, Nils; Kinsley, Les; Jacobsen, Geraldine; Johnson, Sean; Neil, Helen

2017-07-01

Increased export production (EP) in the Subantarctic Zone (SAZ) of the Southern Ocean due to iron fertilisation has been proposed as a key mechanism for explaining carbon drawdown during the last glacial maximum (LGM). This work reconstructs marine EP since the LGM at four sites around New Zealand. For the first time in this region, 230-Thorium-normalised fluxes of biogenic opal, carbonate, excess barium, and organic carbon are presented. In Subtropical Waters and the SAZ, these flux variations show that EP has not changed markedly since the LGM. The only exception is a site currently north of the subtropical front. Here we suggest the subtropical front shifted over the core site between 18 and 12 ka, driving increased EP. To understand why EP remained mostly low and constant elsewhere, lithogenic fluxes at the four sites were measured to investigate changes in dust deposition. At all sites, lithogenic fluxes were greater during the LGM compared to the Holocene. The positive temporal correlation between the Antarctic dust record and lithogenic flux at a site in the Tasman Sea shows that regionally, increased dust deposition contributed to the high glacial lithogenic fluxes. Additionally, it is inferred that lithogenic material from erosion and glacier melting deposited on the Campbell Plateau during the deglaciation (18-12 ka). From these observations, it is proposed that even though increased glacial dust deposition may have relieved iron limitation within the SAZ around New Zealand, the availability of silicic acid limited diatom growth and thus any resultant increase in carbon export during the LGM. Therefore, silicic acid concentrations have remained low since the LGM. This result suggests that both silicic acid and iron co-limit EP in the SAZ around New Zealand, consistent with modern process studies.

Application of soil quality indices to assess the status of agricultural soils irrigated with treated wastewaters

NASA Astrophysics Data System (ADS)

Morugán-Coronado, A.; Arcenegui, V.; García-Orenes, F.; Mataix-Solera, J.; Mataix-Beneyto, J.

2012-12-01

The supply of water is limited in some parts of the Mediterranean region, such as southeastern Spain. The use of treated wastewater for the irrigation of agricultural soils is an alternative to using better-quality water, especially in semi-arid regions. On the other hand, this practice can modify some soil properties, change their relationships, the equilibrium reached and influence soil quality. In this work two soil quality indices were used to evaluate the effects of irrigation with treated wastewater in soils. The indices were developed studying different soil properties in undisturbed soils in SE Spain, and the relationships between soil parameters were established using multiple linear regressions. This study was carried out in three areas of Alicante Province (SE Spain) irrigated with wastewater, including four study sites. The results showed slight changes in some soil properties as a consequence of irrigation with wastewater, the obtained levels not being dangerous for agricultural soils, and in some cases they could be considered as positive from an agronomical point of view. In one of the study sites, and as a consequence of the low quality wastewater used, a relevant increase in soil organic matter content was observed, as well as modifications in most of the soil properties. The application of soil quality indices indicated that all the soils of study sites are in a state of disequilibrium regarding the relationships between properties independent of the type of water used. However, there were no relevant differences in the soil quality indices between soils irrigated with wastewater with respect to their control sites for all except one of the sites, which corresponds to the site where low quality wastewater was used.

Sources of funding for Nobel Prize-winning work: public or private?

PubMed

Tatsioni, Athina; Vavva, Effie; Ioannidis, John P A

2010-05-01

Funding is important for scientists' work and may contribute to exceptional research outcomes. We analyzed the funding sources reported in the landmark scientific papers of Nobel Prize winners. Between 2000 and 2008, 70 Nobel laureates won recognition in medicine, physics, and chemistry. Sixty five (70%) of the 93 selected papers related to the Nobel-awarded work reported some funding source including U.S. government sources in 53 (82%), non-U.S. government sources in 19 (29%), and nongovernment sources in 33 (51%). A substantial portion of this exceptional work was unfunded. We contacted Nobel laureates whose landmark papers reported no funding. Thirteen Nobel laureates responded and offered their insights about the funding process and difficulties inherent in funding. Overall, very diverse sources amounting to a total of 64 different listed sponsors supported Nobel-related work. A few public institutions, in particular the U.S. National Institutes of Health (with n=26 funded papers) and the National Science Foundation (with n=17 papers), stood out for their successful record for funding exceptional research. However, Nobel-level work arose even from completely unfunded research, especially when institutions offered a protected environment for dedicated scientists.

Post-fire hydrologic response in Central Portugal. A four years study at microplot scale.

NASA Astrophysics Data System (ADS)

Vieira, Diana; Malvar, Maruxa; Martins, Martinho; Machado, Ana; Nunes, João; Keizer, Jacob

2014-05-01

Wildfires are a natural phenomenon in regions with a Mediterranean-type climate. However, their present-day widespread occurrence in southern Europe is unprecedented and strongly reflects human activity such as ignition, land-use changes, land abandonment and introduction of highly flammable plantations. Besides wildfires, post-fire management practices such as plowing, terracing, clearcutting and logging should also be considered, since their occurrence is getting increasingly common. And, in a long-term period these practices seem to be executed intercalated with repeated fire occurrences in the same site, sharing the impacts together with fire in an escalated degradational effect. In this sense, the work presented here concerns four years of runoff and erosion data at microplot scale after the wildfire, comparing different land management practices that occurred before the fire. Preliminary results indicate that in four years of monitoring, runoff is constantly higher in plowed sites than in the unplowed ones, with the exception of the first year. Regarding soil losses the plowed plots present always higher sediment rates than the unplowed ones. The comparison between two unplowed sites with different land uses, indicate higher runoff and erosion risk for pine comparatively to the eucalypt ones, however the reduced soil depth in the first can have an important role in these differences. Following these facts, the aim of the present work is to answer the following research questions: i) Do these four years of observations fit with the window of disturbance model presented by Prosser and Williams (1998). or the alternative version by Wittenberg and Inbar (2009)?; ii) Does pre-fire disturbances (wildfire, land use changes and land management practices) still have repercussions after wildfire?; In what sense does four years of intensive monitoring provides that one year couldn't provide?

40 CFR 35.6550 - Procurement system standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... contractors under a Core Program Cooperative Agreement must provide comparable information for all sites... following provisions or their equivalents into all contracts, except those for well-drilling, fence erecting...

40 CFR 35.6550 - Procurement system standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... contractors under a Core Program Cooperative Agreement must provide comparable information for all sites... following provisions or their equivalents into all contracts, except those for well-drilling, fence erecting...

40 CFR 35.6550 - Procurement system standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... contractors under a Core Program Cooperative Agreement must provide comparable information for all sites... following provisions or their equivalents into all contracts, except those for well-drilling, fence erecting...

40 CFR 35.6550 - Procurement system standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... contractors under a Core Program Cooperative Agreement must provide comparable information for all sites... following provisions or their equivalents into all contracts, except those for well-drilling, fence erecting...

Green Tea

MedlinePlus

... symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. Except for decaffeinated green tea ... hard-of-hearing callers): 1-866-464-3615 Web site: nccih.nih.gov E-mail: info@nccih. ...

Exceptionally long 5' UTR short tandem repeats specifically linked to primates.

PubMed

Namdar-Aligoodarzi, P; Mohammadparast, S; Zaker-Kandjani, B; Talebi Kakroodi, S; Jafari Vesiehsari, M; Ohadi, M

2015-09-10

We have previously reported genome-scale short tandem repeats (STRs) in the core promoter interval (i.e. -120 to +1 to the transcription start site) of protein-coding genes that have evolved identically in primates vs. non-primates. Those STRs may function as evolutionary switch codes for primate speciation. In the current study, we used the Ensembl database to analyze the 5' untranslated region (5' UTR) between +1 and +60 of the transcription start site of the entire human protein-coding genes annotated in the GeneCards database, in order to identify "exceptionally long" STRs (≥5-repeats), which may be of selective/adaptive advantage. The importance of this critical interval is its function as core promoter, and its effect on transcription and translation. In order to minimize ascertainment bias, we analyzed the evolutionary status of the human 5' UTR STRs of ≥5-repeats in several species encompassing six major orders and superorders across mammals, including primates, rodents, Scandentia, Laurasiatheria, Afrotheria, and Xenarthra. We introduce primate-specific STRs, and STRs which have expanded from mouse to primates. Identical co-occurrence of the identified STRs of rare average frequency between 0.006 and 0.0001 in primates supports a role for those motifs in processes that diverged primates from other mammals, such as neuronal differentiation (e.g. APOD and FGF4), and craniofacial development (e.g. FILIP1L). A number of the identified STRs of ≥5-repeats may be human-specific (e.g. ZMYM3 and DAZAP1). Future work is warranted to examine the importance of the listed genes in primate/human evolution, development, and disease. Copyright © 2015 Elsevier B.V. All rights reserved.

Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments

PubMed Central

Meng, Fanchi; Na, Insung; Kurgan, Lukasz; Uversky, Vladimir N.

2015-01-01

The cell nucleus contains a number of membrane-less organelles or intra-nuclear compartments. These compartments are dynamic structures representing liquid-droplet phases which are only slightly denser than the bulk intra-nuclear fluid. They possess different functions, have diverse morphologies, and are typically composed of RNA (or, in some cases, DNA) and proteins. We analyzed 3005 mouse proteins localized in specific intra-nuclear organelles, such as nucleolus, chromatin, Cajal bodies, nuclear speckles, promyelocytic leukemia (PML) nuclear bodies, nuclear lamina, nuclear pores, and perinuclear compartment and compared them with ~29,863 non-nuclear proteins from mouse proteome. Our analysis revealed that intrinsic disorder is enriched in the majority of intra-nuclear compartments, except for the nuclear pore and lamina. These compartments are depleted in proteins that lack disordered domains and enriched in proteins that have multiple disordered domains. Moonlighting proteins found in multiple intra-nuclear compartments are more likely to have multiple disordered domains. Protein-protein interaction networks in the intra-nuclear compartments are denser and include more hubs compared to the non-nuclear proteins. Hubs in the intra-nuclear compartments (except for the nuclear pore) are enriched in disorder compared with non-nuclear hubs and non-nuclear proteins. Therefore, our work provides support to the idea of the functional importance of intrinsic disorder in the cell nucleus and shows that many proteins associated with sub-nuclear organelles in nuclei of mouse cells are enriched in disorder. This high level of disorder in the mouse nuclear proteins defines their ability to serve as very promiscuous binders, possessing both large quantities of potential disorder-based interaction sites and the ability of a single such site to be involved in a large number of interactions. PMID:26712748

Report of the Council for Exceptional Children's Task Force on Policy Issues Relating to the Management of Students with Communicable Diseases.

ERIC Educational Resources Information Center

Council for Exceptional Children, Reston, VA.

How schools can effectively work with exceptional students who have communicable diseases was the focus of an eight-member Task Force appointed by the Council for Exceptional Children (CEC) Governmental Relations Committee. Its report begins with an overview of existing guidelines and defines specific communicable diseases (Hepatitis B,…

Summary of International Waste Management Programs (LLNL Input to SNL L3 MS: System-Wide Integration and Site Selection Concepts for Future Disposition Options for HLW)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenberg, Harris R.; Blink, James A.; Halsey, William G.

2011-08-11

The Used Fuel Disposition Campaign (UFDC) within the Department of Energy’s Office of Nuclear Energy (DOE-NE) Fuel Cycle Technology (FCT) program has been tasked with investigating the disposal of the nation’s spent nuclear fuel (SNF) and high-level nuclear waste (HLW) for a range of potential waste forms and geologic environments. This Lessons Learned task is part of a multi-laboratory effort, with this LLNL report providing input to a Level 3 SNL milestone (System-Wide Integration and Site Selection Concepts for Future Disposition Options for HLW). The work package number is: FTLL11UF0328; the work package title is: Technical Bases / Lessons Learned;more » the milestone number is: M41UF032802; and the milestone title is: “LLNL Input to SNL L3 MS: System-Wide Integration and Site Selection Concepts for Future Disposition Options for HLW”. The system-wide integration effort will integrate all aspects of waste management and disposal, integrating the waste generators, interim storage, transportation, and ultimate disposal at a repository site. The review of international experience in these areas is required to support future studies that address all of these components in an integrated manner. Note that this report is a snapshot of nuclear power infrastructure and international waste management programs that is current as of August 2011, with one notable exception. No attempt has been made to discuss the currently evolving world-wide response to the tragic consequences of the earthquake and tsunami that devastated Japan on March 11, 2011, leaving more than 15,000 people dead and more than 8,000 people missing, and severely damaging the Fukushima Daiichi nuclear power complex. Continuing efforts in FY 2012 will update the data, and summarize it in an Excel spreadsheet for easy comparison and assist in the knowledge management of the study cases.« less

Comprehensive assessment of health education and health promotion in five non-communicable disease demonstration districts in China: a cross-sectional study.

PubMed

Xu, Qiaohua; Huang, Yuelong; Chen, Biyun

2017-12-26

This study aims to develop assessment indicators of health education and promotion for non-communicable disease (NCD) demonstration districts in China and to identify significant factors associated with NCD health education and promotion work. Three complementary techniques were used to conduct this study in Hunan Province, China, between late 2013 and 2015. The Delphi technique was used to develop weighted assessment indicators, followed by the rank sum ratio (RSR) to normalise the weights through rank conversion. Lastly, the technique for order of preference by similarity to ideal solution was conducted to assess five randomly selected NCD demonstration districts representing five different orientations in the province. A total of 24 assessment indicators were constructed covering the following sections: organisational management, fund support, personnel supplies, health education and promotion, people's awareness of NCDs, management and control of patients with NCD, satisfaction with health education and promotion and health literacy of residents. Five districts were selected as samples for evaluation (Furong District, Ziyang District, Shaodong County, Shuangfeng County and Luxi County). Performance varied among the sites, with Furong District greatly surpassing the other sites, especially in fund support, media promotion, technical support for publicity materials, community promotion and supportive environment supplies. The latter four factors were also much greater in the second-ranked Luxi County site than those in the other sites (except Furong District). There were gaps in health education and promotion work in NCD demonstration districts in Hunan Province. The districts that performed better had obvious advantages in fund support, media promotion, technical support, community promotion and supportive environment supplies. Our study provided both a methodological reference and an assessment indicator framework for similar future studies. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

15 CFR 265.21 - Improper use of roads as thoroughfares.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Improper use of roads as thoroughfares... § 265.21 Improper use of roads as thoroughfares. Except as otherwise provided herein, no person shall drive a motor vehicle or bicycle onto the site for the sole purpose of using the roads of the site as a...

43 CFR 3162.7-5 - Site security on Federal and Indian (except Osage) oil and gas leases.

Code of Federal Regulations, 2013 CFR

2013-10-01

... connections they were used as well as when they were installed and removed. The site facility diagram(s) shall...-resettable totalizers. There shall be no by-pass piping around the LACT. All components of the LACT that are... possess the identification documentation required by appicable NTL's or onshore Orders while the oil is...

43 CFR 3162.7-5 - Site security on Federal and Indian (except Osage) oil and gas leases.

Code of Federal Regulations, 2014 CFR

2014-10-01

... connections they were used as well as when they were installed and removed. The site facility diagram(s) shall...-resettable totalizers. There shall be no by-pass piping around the LACT. All components of the LACT that are... possess the identification documentation required by appicable NTL's or onshore Orders while the oil is...

43 CFR 3162.7-5 - Site security on Federal and Indian (except Osage) oil and gas leases.

Code of Federal Regulations, 2012 CFR

2012-10-01

... connections they were used as well as when they were installed and removed. The site facility diagram(s) shall...-resettable totalizers. There shall be no by-pass piping around the LACT. All components of the LACT that are... possess the identification documentation required by appicable NTL's or onshore Orders while the oil is...

Biological growth functions describe published site index curves for Lake States timber species.

Treesearch

Allen L. Lundgren; William A. Dolid

1970-01-01

Two biological growth functions, an exponential-monomolecular function and a simple monomolecular function, have been fit to published site index curves for 11 Lake States tree species: red, jack, and white pine, balsam fir, white and black spruce, tamarack, white-cedar, aspen, red oak, and paper birch. Both functions closely fit all published curves except those for...

Growth of 11 introduced tree species on selected forest sites in Hawaii

Treesearch

Michael G Buck; Roger H. Imoto

1982-01-01

Growth and volume data for trees on 25 plots reprsenting 11 introduced species in Hawaii were recorded during a 21-year period. Tree were measured at about 5-year intervals to determine overall growth and stand development. The sites selected were considered better-than-average in terms of elevation, amount of precipitation, and soil quality. Except for redwood, stands...

75 FR 58249 - Migratory Bird Hunting; Final Frameworks for Late-Season Migratory Bird Hunting Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... the Division of Migratory Bird Management's Web site at http://www.fws.gov/migratorybirds/ , or at... under ADDRESSES or from our Web site at http://www.fws.gov/migratorybirds/NewsPublicationsReports.html... recommended raising the dark goose daily bag limit from 4 to 5 geese in the aggregate, with the exception of...

Neuropsychological phenotypes among men with and without HIV disease in the multicenter AIDS cohort study.

PubMed

Molsberry, Samantha A; Cheng, Yu; Kingsley, Lawrence; Jacobson, Lisa; Levine, Andrew J; Martin, Eileen; Miller, Eric N; Munro, Cynthia A; Ragin, Ann; Sacktor, Ned; Becker, James T

2018-05-11

Mild forms of HIV-associated neurocognitive disorder (HAND) remain prevalent in the combination anti-retroviral therapy (cART) era. This study's objective was to identify neuropsychological subgroups within the Multicenter AIDS Cohort Study (MACS) based on the participant-based latent structure of cognitive function and to identify factors associated with subgroups. The MACS is a four-site longitudinal study of the natural and treated history of HIV disease among gay and bisexual men. Using neuropsychological domain scores we used a cluster variable selection algorithm to identify the optimal subset of domains with cluster information. Latent profile analysis was applied using scores from identified domains. Exploratory and post-hoc analyses were conducted to identify factors associated with cluster membership and the drivers of the observed associations. Cluster variable selection identified all domains as containing cluster information except for Working Memory. A three-profile solution produced the best fit for the data. Profile 1 performed below average on all domains, Profile 2 performed average on executive functioning, motor, and speed and below average on learning and memory, Profile 3 performed at or above average across all domains. Several demographic, cognitive, and social factors were associated with profile membership; these associations were driven by differences between Profile 1 and the other profiles. There is an identifiable pattern of neuropsychological performance among MACS members determined by all domains except Working Memory. Neither HIV nor HIV-related biomarkers were related with cluster membership, consistent with other findings that cognitive performance patterns do not map directly onto HIV serostatus.

Array Simulation at the Bearing Stake Sites

DTIC Science & Technology

1981-04-01

C) The array was generally towed at 300 m depth. Four depth sensors on the array gave depth and tilt. With the exception of Site 1B the array was...Site 2, weights were added to the array to overcome its apparent buoyancy. The depth sensors failed on this run and the actual *ilt is not known. Data...horizontal axis title, " Sensor Group Separation," refers to posicion along che array. It .s equivalent to our simulated receiver depth with shallower

Suspended sediment yield of New Jersey coastal plain streams draining into the Delaware estuary

USGS Publications Warehouse

Mansue, Lawrence J.

1972-01-01

The purpose of this report is to summarize sediment data collected at selected stream-sampling sites in southern New Jersey. Computations of excepted average annual yields at each sampling site were made and utilized to estimate the annual yield at ungaged sites. Similar data currently are being compiled for streams draining Pennsylvania and Delaware. It is planned to report on the combined information at a later date in the Geological Survey's Water-Supply Paper series.

Exceptional longevity and exceptionally high metabolic rates in anthropoid primates are linked to a major modification of the ubiquinone reduction site of cytochrome b.

PubMed

Rottenberg, Hagai

2014-10-01

The maximal lifespan of Anthropoid primates (monkeys, apes and humans) exceed the lifespan of most other mammals of equal body mass. Unexpectedly, their exceptional longevity is associated with exceptionally high metabolic rates, in apparent contradiction to the Free Radical Theory of Aging. It was therefore suggested that in anthropoid primates (and several other taxa of mammals and birds) the mitochondrial electron transport complexes evolved to modify the relationship between basal electron transport and superoxide generation to allow for the evolution of exceptional longevity. Cytochrome b, the core protein of the bc1 complex is a major source of superoxide. The amino-acid sequence of cytochrome b evolved much faster in anthropoid than in prosimian primates, and most other mammals, resulting in a large change in the amino-acids composition of the protein. As a result of these changes cytochrome b in anthropoid primates is significantly less hydrophobic and contains more polar residues than other primates and most other mammals. Most of these changes are clustered around the reduction site of uboiquinone. In particular a key positively charged residue, arginine 313, that interacts with propionate D of heme bH, and thus raises its redox potential, is substituted in anthropoid primates with the neutral residue glutamine, most likely resulting in a lower redox potential of heme bH and faster reduction of ubiquinone at high proton motive force. It is suggested that these changes contribute to the observed increased rates of basal metabolism and reduce the rates of superoxide production, thus allowing for increased lifespan.

Skinfold thickness at 8 common cryotherapy sites in various athletic populations.

PubMed

Jutte, Lisa S; Hawkins, Jeremy; Miller, Kevin C; Long, Blaine C; Knight, Kenneth L

2012-01-01

Researchers have observed slower cooling rates in thigh muscle with greater overlying adipose tissue, suggesting that cryotherapy duration should be based on the adipose thickness of the treatment site. Skinfold data do not exist for other common cryotherapy sites, and no one has reported how those skinfolds might vary because of physical activity level or sex. To determine the variability in skinfold thickness among common cryotherapy sites relative to sex and activity level (National Collegiate Athletic Association Division I athletes, recreationally active college athletes). Descriptive laboratory study. Field. Three hundred eighty-nine college students participated; 196 Division I athletes (157 men, 39 women) were recruited during preseason physicals, and 193 recreationally active college athletes (108 men, 85 women) were recruited from physical education classes. Three skinfold measurements to within 1 mm were taken at 8 sites (inferior angle of the scapula, middle deltoid, ulnar groove, midforearm, midthigh, medial collateral ligament, midcalf, and anterior talofibular ligament [ATF]) using Lange skinfold calipers. Skinfold thickness in millimeters. We noted interactions among sex, activity level, and skinfold site. Male athletes had smaller skinfold measurements than female athletes at all sites except the ATF, scapula, and ulnar groove (F₇,₂₇₀₂ = 69.85, P < .001). Skinfold measurements were greater for recreationally active athletes than their Division I counterparts at all sites except the ATF, deltoid, and ulnar groove (F₇,₂₇₀₂ = 30.79, P < .001). Thigh skinfold measurements of recreationally active female athletes were the largest, and their ATF skinfolds were the smallest. Skinfold thickness at common cryotherapy treatment sites varied based on level of physical activity and sex. Therefore, clinicians should measure skinfold thickness to determine an appropriate cryotherapy duration.

Skinfold Thickness at 8 Common Cryotherapy Sites in Various Athletic Populations

PubMed Central

Jutte, Lisa S.; Hawkins, Jeremy; Miller, Kevin C.; Long, Blaine C.; Knight, Kenneth L.

2012-01-01

Context: Researchers have observed slower cooling rates in thigh muscle with greater overlying adipose tissue, suggesting that cryotherapy duration should be based on the adipose thickness of the treatment site. Skinfold data do not exist for other common cryotherapy sites, and no one has reported how those skinfolds might vary because of physical activity level or sex. Objective: To determine the variability in skinfold thickness among common cryotherapy sites relative to sex and activity level (National Collegiate Athletic Association Division I athletes, recreationally active college athletes). Design: Descriptive laboratory study. Setting: Field. Patients or Other Participants: Three hundred eighty-nine college students participated; 196 Division I athletes (157 men, 39 women) were recruited during preseason physicals, and 193 recreationally active college athletes (108 men, 85 women) were recruited from physical education classes. Intervention(s): Three skinfold measurements to within 1 mm were taken at 8 sites (inferior angle of the scapula, middle deltoid, ulnar groove, midforearm, midthigh, medial collateral ligament, midcalf, and anterior talofibular ligament [ATF]) using Lange skinfold calipers. Main Outcome Measure(s): Skinfold thickness in millimeters. Results: We noted interactions among sex, activity level, and skinfold site. Male athletes had smaller skinfold measurements than female athletes at all sites except the ATF, scapula, and ulnar groove (F7,2702 = 69.85, P < .001). Skinfold measurements were greater for recreationally active athletes than their Division I counterparts at all sites except the ATF, deltoid, and ulnar groove (F7,2702 = 30.79, P < .001). Thigh skinfold measurements of recreationally active female athletes were the largest, and their ATF skinfolds were the smallest. Conclusions: Skinfold thickness at common cryotherapy treatment sites varied based on level of physical activity and sex. Therefore, clinicians should measure skinfold thickness to determine an appropriate cryotherapy duration. PMID:22488282

7 CFR 3575.25 - Ineligible loan purposes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... over tenants and services offered except for industrial-site infrastructure development, (b) Facilities... facilities, (d) Telephone systems, (e) Facilities which are not modest in size, design, and cost, (f) Finder...

Vendors: Gifts Are the Exception to the Rule.

ERIC Educational Resources Information Center

Natale, Jo Anna

1992-01-01

Informal interviews with several people working in different industries reveal that, without exception, the vendors say companies do not routinely offer school officials gifts and entertainment to sway purchasing decisions, but that it does happen. (MLF)

Genomic profiling of multiple sequentially acquired tumor metastatic sites from an “exceptional responder” lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response. | Center for Cancer Research

Cancer.gov

Biswas et al. describe an “exceptional responder” lung adenocarcinoma patient who survived with metastatic lung adenocarcinoma for 7 years while undergoing single or combination ERBB2-directed therapies. Whole-genome, whole-exome, and high-coverage ion-torrent targeted sequencing were used to demonstrate extreme genomic heterogeneity between the lung and lymph node metastatic

Spatial patterns in occupancy and reproduction of Golden Eagles during drought: Prospects for conservation in changing environments

USGS Publications Warehouse

Wiens, David; Kolar, Patrick; Hunt, W. Grainger; Hunt, Teresa; Fuller, Mark R.; Bell, Douglas A.

2018-01-01

We used a broad-scale sampling design to investigate spatial patterns in occupancy and breeding success of territorial pairs of Golden Eagles (Aquila chrysaetos) in the Diablo Range, California, USA, during a period of exceptional drought (2014–2016). We surveyed 138 randomly selected sample sites over 4 occasions each year and identified 199 pairs of eagles, 100 of which were detected in focal sample sites. We then used dynamic multistate modeling to identify relationships between site occupancy and reproduction of Golden Eagles relative to spatial variability in landscape composition and drought conditions. We observed little variability among years in site occupancy (3-yr mean = 0.74), but the estimated annual probability of successful reproduction was relatively low during the study period and declined from 0.39 (± 0.08 SE) to 0.18 (± 0.07 SE). Probabilities of site occupancy and reproduction were substantially greater at sample sites that were occupied by successful breeders in the previous year, indicating the presence of sites that were consistently used by successfully reproducing eagles. We found strong evidence for nonrandom spatial distribution in both occupancy and reproduction: Sites with the greatest potential for occupancy were characterized by rugged terrain conditions with intermediate amounts of grassland interspersed with patches of oak woodland and coniferous forest, whereas successful reproduction was most strongly associated with the amount of precipitation that a site received during the nesting period. Our findings highlight the contribution of consistently occupied and productive breeding sites to overall productivity of the local breeding population, and show that both occupancy and reproduction at these sites were maintained even during a period of exceptional drought. Our approach to quantifying and mapping site quality should be especially useful for the spatial prioritization of compensation measures intended to help offset the impacts of increasing human land use and development on Golden Eagles and their habitats.

36 CFR 261.52 - Fire.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... (c) Smoking. (d) Smoking, except within an enclosed vehicle or building, a developed recreation site... concerning burning, fires or which is for the purpose of preventing, or restricting the spread of fires. [42...

48 CFR 245.607-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the plant clearance officer after an on-site survey, if inventory is considered without value except for scrap. If approved, the contractor may make a single descriptive entry on an inventory schedule...

Associations of psychosocial working conditions and working time characteristics with somatic complaints in German resident physicians.

PubMed

Fischer, Nina; Degen, Christiane; Li, Jian; Loerbroks, Adrian; Müller, Andreas; Angerer, Peter

2016-05-01

Somatic complaints (SC) are highly prevalent in working populations and cause suffering and extensive health-care utilization. Adverse psychosocial working conditions as conceptualized in the Job Demand-Control-Support Model (JDC-S) and adverse working time characteristics (WTC) are potential risk factors. This combination is particularly common in hospital physicians. This study examines associations of JDC-S and WTC with SC in resident physicians from Germany. A cross-sectional study was conducted among 405 physicians at the end of residency training. SC were measured using the Giessen Subjective Complaints List (GBB-24) containing the sub-categories exhaustion, gastrointestinal, musculoskeletal, and cardiovascular complaints. Data on working conditions were collected by a self-report method for work analysis in hospitals (TAA-KH-S) and by questions on WTC (i.e., working hours). Multivariable stepwise regression analyses were applied. Workload showed the most pronounced relationship with all sub-categories of SC except gastrointestinal complaints. Job autonomy was not significantly related to any SC sub-category. Social support at work was inversely associated with all SC sub-categories except for cardiovascular complaints. Free weekends were associated with reduced SC except for exhaustion. Shift work was related to an increased SC total score and musculoskeletal complaints. Working hours showed no association with SC. In resident physicians, high workload and shift work are associated with increased SC, while social support at work and free weekends are associated with decreased SC. These insights may inform the development of preventive measures to improve the health of this professional group. Prospective studies are needed though to corroborate our findings.

Work site stress management: national survey results.

PubMed

Fielding, J E

1989-12-01

The National Survey of Work Site Health Promotion Activities established baseline data on the frequency of nine types of health promotion activity at private work sites with more than 50 employees in the United States. Stress management activities were provided at 26.6% of work sites. Types of activities at those work sites with some stress management activity included group counseling (58.5%), individual counseling (39.3%), follow-up counseling (25.9%), special events (11.5%), providing information about stress (80.7%), providing a place to relax (64.8%), and making organizational changes to reduce employee stress (81.2%). Frequency of activities varied by industry type and by region of the country. Incidence of most types of activities did not increase as work site size increased, although the likelihood of having any of these activities did increase with work site size. Stress management activities were more likely to be present at work sites with a medical staff or health educator. An increase in output, productivity, or quality was the most frequently cited benefit (46.5%). Negative effects were reported at 2.6% of the work sites. Other health promotion activities found at the work sites surveyed included smoking cessation (61.8%), treatment and control of high blood pressure (36.7%), and weight control (34.7%). Employee Assistance Programs were responsible for stress management at 62% of the work sites with an Employee Assistance Program.

Statistical Debugging

DTIC Science & Technology

2008-03-01

in all parts of the program except the predicates. B. PRELIMINARY EXPERIMENTATION Working with the hand written program initially to get a feel...PROBLEM STATEMENT AND MOTIVATION .......................................2 II. RELATED WORK ...ISOLATION.........................................7 III. PRELIMINARY WORK

MOTIFSIM 2.1: An Enhanced Software Platform for Detecting Similarity in Multiple DNA Motif Data Sets

PubMed Central

Huang, Chun-Hsi

2017-01-01

Abstract Finding binding site motifs plays an important role in bioinformatics as it reveals the transcription factors that control the gene expression. The development for motif finders has flourished in the past years with many tools have been introduced to the research community. Although these tools possess exceptional features for detecting motifs, they report different results for an identical data set. Hence, using multiple tools is recommended because motifs reported by several tools are likely biologically significant. However, the results from multiple tools need to be compared for obtaining common significant motifs. MOTIFSIM web tool and command-line tool were developed for this purpose. In this work, we present several technical improvements as well as additional features to further support the motif analysis in our new release MOTIFSIM 2.1. PMID:28632401

Multi-site pain and working conditions as predictors of work ability in a 4-year follow-up among food industry employees.

PubMed

Neupane, S; Virtanen, P; Leino-Arjas, P; Miranda, H; Siukola, A; Nygård, C-H

2013-03-01

We investigated the separate and joint effects of multi-site musculoskeletal pain and physical and psychosocial exposures at work on future work ability. A survey was conducted among employees of a Finnish food industry company in 2005 (n = 1201) and a follow-up survey in 2009 (n = 734). Information on self-assessed work ability (current work ability on a scale from 0 to 10; 7 = poor work ability), multi-site musculoskeletal pain (pain in at least two anatomical areas of four), leisure-time physical activity, body mass index and physical and psychosocial exposures was obtained by questionnaire. The separate and joint effects of multi-site pain and work exposures on work ability at follow-up, among subjects with good work ability at baseline, were assessed by logistic regression, and p-values for the interaction derived. Compared with subjects with neither multi-site pain nor adverse work exposure, multi-site pain at baseline increased the risk of poor work ability at follow-up, allowing for age, gender, occupational class, body mass index and leisure-time physical activity. The separate effects of the work exposures on work ability were somewhat smaller than those of multi-site pain. Multi-site pain had an interactive effect with work environment and awkward postures, such that no association of multi-site pain with poor work ability was seen when work environment was poor or awkward postures present. The decline in work ability connected with multi-site pain was not increased by exposure to adverse physical or psychosocial factors at work. © 2012 European Federation of International Association for the Study of Pain Chapters.

44 CFR 206.226 - Restoration of damaged facilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... original site will be approved, except those facilities which facilitate an open space use in accordance... replacement items. (i) Library books and publications. Replacement of library books and publications is based...

44 CFR 206.226 - Restoration of damaged facilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... original site will be approved, except those facilities which facilitate an open space use in accordance... replacement items. (i) Library books and publications. Replacement of library books and publications is based...

Exceptional preservation of children's footprints from a Holocene footprint site in Namibia

NASA Astrophysics Data System (ADS)

Bennett, Matthew R.; Morse, Sarita A.; Liutkus-Pierce, Cynthia; McClymont, Juliet; Evans, Mary; Crompton, Robin H.; Francis Thackeray, J.

2014-09-01

Here we report on a Holocene inter-dune site close to Walvis Bay (Namibia) which contains exceptionally well-preserved children's footprints. The footprint surface is dated using Optically Stimulated Luminescence (OSL) methods to approximately 1.5 ka. These dates are compared to those obtained at nearby footprint sites and used to verify a model of diachronous footprint surfaces and also add to the archaeological data available for the communities that occupied these near-coastal areas during the Holocene. This model of diachronous footprint surfaces has implications for other soft-sediment footprint sites such as the 1.5 Ma old footprints at Ileret (Kenya). The distribution of both human and animal tracks, is consistent with the passage of small flock of small ungulates (probably sheep/goats) followed by a group of approximately 9 ± 2 individuals (children or young adults). Age estimates from the tracks suggest that some of the individuals may have been as young as five years old. Variation in track topology across this sedimentologically uniform surface is explained in terms of variations in gait and weight/stature of the individual print makers and is used to corroborate a model of footprint morphology developed at a nearby site. The significance of the site within the literature on human footprints lies in the quality of the track preservation, their topological variability despite a potentially uniform substrate, and the small size of the tracks, and therefore the inferred young age of the track-makers. The site provides an emotive insight into the life of the track-makers.

Occurrence of and trends in selected sediment-associated contaminants in Caddo Lake, East Texas, 1940-2002

USGS Publications Warehouse

Wilson, Jennifer T.

2003-01-01

Bottom-sediment cores were collected from four sites in Caddo Lake in East Texas during May 2002 for analyses of radionuclides (for age dating), organochlorine pesticides, polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and major and trace elements, and to describe the occurrence and trends of these sediment-associated contaminants. The Goose Prairie Creek and Harrison Bayou sites receive drainage from an area that includes parts of the now-closed Longhorn Army Ammunitions Plant. The mid-lake site is relatively close to dense oil and gas operations in the lake. The Carter Lake site receives minimal discharge from developed areas. Sediment age (deposition) dates represented in the cores ranged from 1940 to 2002. The only organochlorine compounds detected in all core samples were the DDT degradation products DDE or DDD, and PCB Aroclors 1242, 1254, and 1260 were detected only at the Goose Prairie Creek site. One or more of the DDE concentrations at all sites exceeded a consensus-based threshold effect concentration (on benthic biota), but none exceeded a consensus-based probable effect concentration. The Goose Prairie Creek site had significant downward trends in concentrations of organochlorine compounds, except for no trend in DDE concentrations. The Ammunitions Plant is a possible historical source of the few organochlorine compounds detected at the Goose Prairie Creek and Harrison Bayou sites. PAH concentrations at all sites were below respective threshold effect concentrations. Highest PAH concentrations at all four sites were of C2- alkylated naphthalenes. Nearly all statistically significant PAH trends in the cores were downward. On the basis of PAH source-indicator ratios, the majority of PAH compounds appear to have originated from uncombusted sources such as leaks or spills from oil and gas operations or vehicles (automobiles, boats, aircraft) in the Caddo Lake area. Concentrations of several of the eight trace elements with threshold effect concentrations and probable effect concentrations (among 26 analyzed) were above the respective threshold effect concentrations, but all, except one lead concentration at the Goose Prairie Creek site (deposited about 1961), were below respective probable effect concentrations. Among trace element concentrations at the four sites, lead and mercury were consistently relatively high at the Goose Prairie Creek site. Again the Ammunitions Plant, because of its proximity and history of industrial activities, is the suspected primary source. Statistically significant trends in trace element concentrations were mixed, but more were downward than upward. Computations to indicate the dominant source (atmospheric fallout or drainage area) of mercury to the Caddo Lake sediment core sites (except Carter Lake) indicate that about one-third of the mercury at the Goose Prairie Creek site might result from drainage area sources. No drainage area sources were indicated for the Harrison Bayou and mid-lake sites. Arsenic, cadmium, and zinc concentrations were highest at the Carter Lake site. No relation between the relatively higher trace element concentrations and any potential source of contamination in the Carter Lake drainage area (for example, oil and gas operations, a road, a boat ramp) is indicated.

Intake port

DOEpatents

Mendler, Edward Charles

2005-02-01

The volumetric efficiency and power of internal combustion engines is improved with an intake port having an intake nozzle, a venturi, and a surge chamber. The venturi is located almost halfway upstream the intake port between the intake valves and the intake plenum enabling the venturi throat diameter to be exceptionally small for providing an exceptionally high ram velocity and an exceptionally long and in turn high efficiency diffuser flowing into the surge chamber. The intake port includes an exceptionally large surge chamber volume for blow down of the intake air into the working cylinder of the engine.

Neuronal correlate of visual associative long-term memory in the primate temporal cortex

NASA Astrophysics Data System (ADS)

Miyashita, Yasushi

1988-10-01

In human long-term memory, ideas and concepts become associated in the learning process1. No neuronal correlate for this cognitive function has so far been described, except that memory traces are thought to be localized in the cerebral cortex; the temporal lobe has been assigned as the site for visual experience because electric stimulation of this area results in imagery recall,2 and lesions produce deficits in visual recognition of objects3-9. We previously reported that in the anterior ventral temporal cortex of monkeys, individual neurons have a sustained activity that is highly selective for a few of the 100 coloured fractal patterns used in a visual working-memory task10. Here I report the development of this selectivity through repeated trials involving the working memory. The few patterns for which a neuron was conjointly selective were frequently related to each other through stimulus-stimulus association imposed during training. The results indicate that the selectivity acquired by these cells represents a neuronal correlate of the associative long-term memory of pictures.

Benthic macroinvertebrate community structural and functional group response to cooling water discharge in the Savannah River and a coastal plain tributary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poff, N.L.; Matthews, R.A.

1984-01-01

Benthic macroinvertebrate community structure and functional groups on leaf detritus in a thermal, post-thermal and an undisturbed stream, and in the Savannah River immediately downstream from each stream mouth, were compared over a 7 wk (48d) period from December 1982 to February 1983. Ambient temperatures n the post-thermal and undisturbed streams ranged from 4 to 8 and 4 to 11/sup 0/C, respectively, and from 7 to 12/sup 0/C in the Savannah River. Temperatures in the thermal stream fluctuated irregularly between 7 to 31/sup 0/C and in the river below this stream mouth between 7 to 22/sup 0/C. A total ofmore » 13,993 macroinvertebrates representing at least 51 families and 84 genera was collected. Numbers of organisms and taxa were depressed at the thermal stream site, whereas numbers of both organisms and taxa increased at the river site receiving thermal influence. Chironomids of the subfamily Orthocladiinae comprised 46 to 60% of the fauna at all sites except in the thermal stream, where they comprised 5%. Physa (Gastropoda), Ablabesmyia (Tanypodinae) and Tanytarsus (Chironominae) each contributed over 20% of the fauna at the thermal stream. Cheumatopsyche (Trichoptera) represented 12 to 13% of the riverine fauna at the ambient sites, but 25% at the thermally-perturbed site. Collectors (mostly gatherers) contributed 51 to 75% at all sites except the thermal stream where scrapers dominated with 39%. Filterer relative abundance increased from 16 to 19% at the ambient river sites to 29% at the thermally-perturbed river site, suggesting that suspended carbon transport from the thermal stream occurred and subsidized the macroinvertebrate community in the Savannah River. 48 references, 3 figures, 2 tables.« less

Local Contributors and Predictability of Flash Drought at the Marena Oklahoma In Situ Sensor Testbed (MOISST) During 2012

NASA Astrophysics Data System (ADS)

Basara, J. B.; Otkin, J.; Mahan, H. R.; Anderson, M. C.; Hain, C.; Wagle, P.; Xiao, X.

2014-12-01

The Marena Oklahoma In Situ Sensor Testbed (MOISST) site was installed in May 2010 as part of the calibration and validation program for the NASA Soil Moisture Active Passive (SMAP) mission. The site includes more than 200 soil, vegetation, and atmospheric sensors installed over an approximately 64 hectare pasture in Central Oklahoma with 4 main stations and multiple sensors installed in profiles. Additional sensors located at the site include a COsmic-ray Soil Moisture Observing System, global position system reflectometers, a passive distributed temperature system, an eddy correlation flux tower, and a phenocam. During 2012, flash drought conditions occurred at the MOISST location as conditions transitioned from no drought in late April to D4 (exceptional drought) in mid August. The array of instruments captured the dramatic transition of land-surface conditions at the MOISST site, in particular during a period spanning approximately six weeks in July and August in whereby drought conditions changed from abnormally dry to exceptional drought and ecosystem collapsed occurred. Results for the analyses demonstrated that both soil moisture and vegetation dynamics were critical components to flash drought development. Further, when the Evaporative Stress Index (ESI) was applied to the MOISST site during 2012, the results demonstrated that the predictability of drought conditions were increased to nearly six weeks prior to flash drought development that began in July.

Sharing Ideas: Making Earth and Space Science Accessible

NASA Astrophysics Data System (ADS)

Runyon, C. J.; Guimond, K.; Atkinson, C.

2005-12-01

There are nearly six million K-12 students with some form of disability in the U.S. and the majority of them are required to achieve the same academic levels as their non-impaired peers. Historically, students with disabilities have experienced difficulties in fully accessing and participating in middle school and high school science programs. With the passage of the No Child Left Behind (NCLB) Act and increasing focus on reading and math performance, many students with exceptional needs are now being taught science by mainstream science teachers, who have little to no training on how to work with students with exceptional needs. For the past 5 years, SERCH has engaged in organizing and hosting a series of Exceptional Space Science Materials for Exceptional Students Workshops (ENWS) focused on educating students with special needs about the space sciences. Each workshop has focused on a different aspect of formal and informal education and working with the various special needs. In all of these workshops, participants experience what a person or student with special needs might encounter when working through educational activities or exhibits by experiencing it first-hand. In addition to making many of NASA's education materials accessible for all learners, a top-ten list of "best practices" has been compiled by the professional educators as a result of our working together for five years and their formal and informal educational experiences.

32 CFR 505.4 - Collecting personal information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.4 Collecting personal information. (a) General... information on public Web sites without the express permission of the user. Requests for exceptions must be...

77 FR 12273 - Public Availability of Department of Energy FY 2011 Service Contract Inventory

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

.../sites/default/files/omb/procurement/memo/service-contract-inventories-guidance-11052010.pdf . On.../files/omb/procurement/memo/service-contract-inventory-guidance.pdf . Except for minor changes to...

Oil and Gas Stormwater Permitting Documents

EPA Pesticide Factsheets

This final rule exempts construction activities at oil and gas sites from the requirement to obtain an NPDES permit for stormwater discharges except in very limited instances. This rule is effective June 12, 2006.

Department of Defense Agency Financial Report for FY 2011

DTIC Science & Technology

2011-11-01

in size. They range from the very small (an unoccupied site supporting a single navigational aid that sits on less than one-half acre of land) to...U.S. military presence in Iraq will be zero troops (except for a small number under Chief of Mission authority). 48,770 50,000 46,000 1.2.2...number of pieces of rolling stock in Iraq supporting U.S. military troops, will be zero (except for a small number used by military personnel under

Identifying personal microbiomes using metagenomic codes

PubMed Central

Franzosa, Eric A.; Huang, Katherine; Meadow, James F.; Gevers, Dirk; Lemon, Katherine P.; Bohannan, Brendan J. M.; Huttenhower, Curtis

2015-01-01

Community composition within the human microbiome varies across individuals, but it remains unknown if this variation is sufficient to uniquely identify individuals within large populations or stable enough to identify them over time. We investigated this by developing a hitting set-based coding algorithm and applying it to the Human Microbiome Project population. Our approach defined body site-specific metagenomic codes: sets of microbial taxa or genes prioritized to uniquely and stably identify individuals. Codes capturing strain variation in clade-specific marker genes were able to distinguish among 100s of individuals at an initial sampling time point. In comparisons with follow-up samples collected 30–300 d later, ∼30% of individuals could still be uniquely pinpointed using metagenomic codes from a typical body site; coincidental (false positive) matches were rare. Codes based on the gut microbiome were exceptionally stable and pinpointed >80% of individuals. The failure of a code to match its owner at a later time point was largely explained by the loss of specific microbial strains (at current limits of detection) and was only weakly associated with the length of the sampling interval. In addition to highlighting patterns of temporal variation in the ecology of the human microbiome, this work demonstrates the feasibility of microbiome-based identifiability—a result with important ethical implications for microbiome study design. The datasets and code used in this work are available for download from huttenhower.sph.harvard.edu/idability. PMID:25964341

TerraSAR-X time-series interferometry detects human-induce subsidence in the Historical Centre of Hanoi, Vietnam

NASA Astrophysics Data System (ADS)

Le, Tuan; Chang, Chung-Pai; Nguyen, Xuan

2016-04-01

Hanoi was the capital of 12 Vietnamese dynasties, where the most historical relics, archaeological ruins and ancient monuments are located over Vietnam. However, those heritage assets are threatened by the land subsidence process occurred in recent decades, which mainly triggered by massive groundwater exploitation and construction activities. In this work, we use a set of high resolution TerraSAR-X images to map small-scale land subsidence patterns in the Historical Centre of Hanoi from April 2012 to November 2013. Images oversampling is integrated into the Small Baseline InSAR processing chain in order to enlarge the monitoring coverage by increasing the point-wise measurements, maintaining the monitoring scale of single building and monument. We analyzed over 2.4 million radar targets on 13.9 km2 area of interest based on 2 main sites: The Citadel, the Old Quarter and French Quarter. The highest subsidence rate recorded is -14.2 mm/year. Most of the heritage assets are considered as stable except the Roman Catholic Archdiocese and the Ceramic Mosaic Mural with the subsidence rates are -14.2 and -13.7 mm/year, respectively. Eventually, optical image and soil properties map are used to determine the causes of subsidence patterns. The result shows the strong relationships between the existing construction sites, the component of sediments and land subsidence processes that occurred in the study site.

Isotopic Fingerprints of Iron-Cyanide Complexes in the Environment.

PubMed

Mansfeldt, Tim; Höhener, Patrick

2016-07-19

Tracing the origin of iron-cyanide complexes in the environment is important because these compounds are potentially toxic. We determined the stable isotopic compositions of cyanide-carbon (CCN) and cyanide-nitrogen (NCN) in 127 contaminated solids and 11 samples of contaminated groundwater from coal carbonization sites, blast furnace operations, and commercial cyanide applications. Coal-carbonization-related cyanides had unique high mean δ(13)CCN values of -10.5 ± 3.5‰ for the solids and -16.1 ± 1.2‰ for the groundwater samples, while the values for blast furnace sludge (-26.9 ± 1.5‰), commercial cyanides (-26.0 ± 3.0‰), and their corresponding groundwaters were significantly lower. Determination of δ(13)CCN is a promising tool for identifying the source of cyanide contamination. However, for coal carbonization sites, historical research into the manufacturing process is necessary because a nonconventional gas works site exhibited exceptionally low δ(13)CCN values of -22.7 ± 1.7‰. The δ(15)NCN values for samples related to coal carbonization and blast furnaces overlapped within a range of +0.1 to +10.3‰, but very high δ(15)NCN values seemed to be indicative for a cyanide source in the blast furnace. In contrast, commercial cyanides tend to have lower δ(15)NCN values of -5.6 to +1.9‰ in solids and -0.5 to +3.0‰ in the groundwater.

In Situ Localization of Ribosomal Sites in Peckoltia and Ancistomus (Loricariidae: Hypostominae) from the Amazon Basin.

PubMed

Pety, Ananda Marques; Cardoso, Adauto Lima; Nagamachi, Cleusa Yoshiko; Pieczarka, Julio Cesar; de Sousa, Leandro Melo; Noronha, Renata Coelho Rodrigues

2018-06-01

Loricariidae is a diverse group of fish from the neotropical region, occupying a wide variety of freshwater environments. Cytogenetic data have brought important insights into Loricariidae diversity because they help validate undescribed species as well as our understanding of inter- and intraspecific diversity. However, conventional cytogenetic approaches are limited in their ability to detect variability in some lineages, as seen in the Peckoltia clade, owing to their apparent conserved karyotype. Thus, the aim of this work was to map 5S and 18S ribosomal (rDNA) sites in five species of Peckoltia and one species of Ancistomus from the Amazon basin, and discusses the mechanisms of organization and diversification of these clusters. The species analyzed were found to have 2n = 52 and share KF = 38 m-sm +14st-a chromosomes, except Peckoltia vittata with KF = 34 m-sm +18st-a. Extensive variations in the number and location of 5S and 18S rDNA sites were observed among species. These data indicate that inversions are not the most important events in karyotype evolution in this group, and should prove useful in identifying the species studied here. In addition to inversions, transpositions are important evolutionary events that are involved at least in rDNA clusters spreading in Peckoltia and probably in other species of Hypostominae.

Work-related determinants of multi-site musculoskeletal pain among employees in the health care sector.

PubMed

Neupane, Subas; Nygård, Clas-Håkan; Oakman, Jodi

2016-06-16

Work-related musculoskeletal pain is a major occupational problem. Those with pain in multiple sites usually report worse health outcomes than those with pain in one site. This study explored prevalence and associated predictors of multi-site pain in health care sector employees. Survey responses from 1348 health care sector employees across three organisations (37% response rate) collected data on job satisfaction, work life balance, psychosocial and physical hazards, general health and work ability. Musculoskeletal discomfort was measured across 5 body regions with pain in ≥ 2 sites defined as multi-site pain. Generalized linear models were used to identify relationships between work-related factors and multi-site pain. Over 52% of the employees reported pain in multiple body sites and 19% reported pain in one site. Poor work life balance (PRR = 2.33, 95% CI = 1.06-5.14). physical (PRR = 7.58, 95% CI = 4.89-11.77) and psychosocial (PRR = 1.59, 95% CI = 1.00-2.57) hazard variables were related to multi-site pain (after controlling for age, gender, health and work ability. Older employees and females were more likely to report multi-site pain. Effective risk management of work related multi-site pain must include identification and control of psychosocial and physical hazards.

10 CFR 52.27 - Limited work authorization after issuance of early site permit.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Limited work authorization after issuance of early site..., AND APPROVALS FOR NUCLEAR POWER PLANTS Early Site Permits § 52.27 Limited work authorization after issuance of early site permit. A holder of an early site permit may request a limited work authorization in...

10 CFR 52.27 - Limited work authorization after issuance of early site permit.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Limited work authorization after issuance of early site..., AND APPROVALS FOR NUCLEAR POWER PLANTS Early Site Permits § 52.27 Limited work authorization after issuance of early site permit. A holder of an early site permit may request a limited work authorization in...

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Quarterly Environmental Data Summary (QEDS) for the fourth quarter of 1997 is prepared in support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement. The data presented constitute the QEDS. The data were received from the contract laboratories, verified by the Weldon Spring Site verification group and, except for air monitoring data and site KPA generated data (uranium analyses), merged into the data base during the fourth quarter of 1997. Air monitoring data presented are the most recent complete sets of quarterly data. Air data are not stored in the data base and KPA data are notmore » merged into the regular data base. Significant data, defined as data values that have exceeded defined ``above normal`` level 2 values, are discussed in this letter for Environmental Monitoring Plan (EMP) generated data only. Above normal level 2 values are based, in ES and H procedures, on historical high values, DOE Derived Concentration Guides (DCGs), NPDES limits and other guidelines. The procedures also establish actions to be taken in response to such data. Data received and verified during the fourth quarter were within a permissible range of variability except for those which are detailed.« less

Single-particle speciation of alkylamines in ambient aerosol at five European sites.

PubMed

Healy, Robert M; Evans, Greg J; Murphy, Michael; Sierau, Berko; Arndt, Jovanna; McGillicuddy, Eoin; O'Connor, Ian P; Sodeau, John R; Wenger, John C

2015-08-01

Alkylamines are associated with both natural and anthropogenic sources and have been detected in ambient aerosol in a variety of environments. However, little is known about the ubiquity or relative abundance of these species in Europe. In this work, ambient single-particle mass spectra collected at five sampling sites across Europe have been analysed for their alkylamine content. The aerosol time-of-flight mass spectrometer (ATOFMS) data used were collected in Ireland (Cork), France (Paris, Dunkirk and Corsica) and Switzerland (Zurich) between 2008 and 2013. Each dataset was queried for mass spectral marker ions associated with the following ambient alkylamines: dimethylamine (DMA), trimethylamine (TMA), diethylamine (DEA), triethylamine (TEA), dipropylamine (DPA) and tripropylamine (TPA). The fraction of ambient particles that contained detectable alkylamines ranged from 1 to 17 % depending on location, with the highest fractions observed in Paris and Zurich in the winter months. The lowest fractions were observed at coastal sites, where the influence of animal husbandry-related alkylamine emissions is also expected to be lowest. TMA was the most ubiquitous particle phase alkylamine detected and was observed at all locations. Alkylamines were found to be internally mixed with both sulphate and nitrate for each dataset, suggesting that aminium salt formation may be important at all sites investigated. Interestingly, in Corsica, all alkylamine particles detected were also found to be internally mixed with methanesulphonic acid (MSA), indicating that aminium methanesulphonate salts may represent a component of marine ambient aerosol in the summer months. Internal mixing of alkylamines with sea salt was not observed, however. Alkylamine-containing particle composition was found to be reasonably homogeneous at each location, with the exception of the Corsica and Dunkirk sites, where two and four distinct mixing states were observed, respectively.

Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota

PubMed Central

Kirouac, Kevin N.; Ling, Hong

2011-01-01

The 8-oxo-guanine (8-oxo-G) lesion is the most abundant and mutagenic oxidative DNA damage existing in the genome. Due to its dual coding nature, 8-oxo-G causes most DNA polymerases to misincorporate adenine. Human Y-family DNA polymerase iota (polι) preferentially incorporates the correct cytosine nucleotide opposite 8-oxo-G. This unique specificity may contribute to polι’s biological role in cellular protection against oxidative stress. However, the structural basis of this preferential cytosine incorporation is currently unknown. Here we present four crystal structures of polι in complex with DNA containing an 8-oxo-G lesion, paired with correct dCTP or incorrect dATP, dGTP, and dTTP nucleotides. An exceptionally narrow polι active site restricts the purine bases in a syn conformation, which prevents the dual coding properties of 8-oxo-G by inhibiting syn/anti conformational equilibrium. More importantly, the 8-oxo-G base in a syn conformation is not mutagenic in polι because its Hoogsteen edge does not form a stable base pair with dATP in the narrow active site. Instead, the syn 8-oxo-G template base forms the most stable replicating base pair with correct dCTP due to its small pyrimidine base size and enhanced hydrogen bonding with the Hoogsteen edge of 8-oxo-G. In combination with site directed mutagenesis, we show that Gln59 in the finger domain specifically interacts with the additional O8 atom of the lesion base, which influences nucleotide selection, enzymatic efficiency, and replication stalling at the lesion site. Our work provides the structural mechanism of high-fidelity 8-oxo-G replication by a human DNA polymerase. PMID:21300901

28 CFR 545.26 - Performance pay provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... categories as quality of work, quantity of work, initiative, ability to learn, dependability, response to... inmate may receive special bonus pay based on the inmate's exceptional work in a temporary job assignment... WORK AND COMPENSATION Inmate Work and Performance Pay Program § 545.26 Performance pay provisions. (a...

28 CFR 545.26 - Performance pay provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... categories as quality of work, quantity of work, initiative, ability to learn, dependability, response to... inmate may receive special bonus pay based on the inmate's exceptional work in a temporary job assignment... WORK AND COMPENSATION Inmate Work and Performance Pay Program § 545.26 Performance pay provisions. (a...

48 CFR 452.211-72 - Statement of Work/Specifications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Statement of Work... Statement of Work/Specifications. As prescribed in 411.171, insert the following clause: Statement of Work... facilities (except as otherwise specified), to perform the Statement of Work/Specifications referenced in...

Memorandum of Understanding Between U.S. EPA Superfund and U.S. NRC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, Stuart

2008-01-15

The Environmental Protection Agency (EPA) Office of Superfund Remediation and Technology Innovation (OSRTI) and the Nuclear Regulatory Commission (NRC) are responsible for implementing the 'Memorandum of Understanding Between the Environmental Protection Agency and the Nuclear Regulatory Commission: Consultation and Finality on Decommissioning and Decontamination of Contaminated Sites'. This paper provides a brief overview of the origin of the Memorandum of Understanding (MOU), the major features of the MOU, and how the MOU has been implemented site specifically. EPA and NRC developed the MOU in response to direction from the House Committee on Appropriations to EPA and NRC to work togethermore » to address the potential for dual regulation. The MOU was signed by EPA on September 30, 2002 and NRC on October 9, 2002. The two agencies had worked on the MOU since March 2000. While both EPA and NRC have statutory authority to clean up these sites, the MOU provides consultation procedures between EPA and NRC to eliminate dual regulation. Under the MOU, EPA and NRC identified the interactions of the two agencies for the decommissioning and decontamination of NRC-licensed sites and the ways in which those responsibilities will be exercised. Except for Section VI, which addresses corrective action under the Resource Conservation and Recovery Act (RCRA), this MOU is limited to the coordination between EPA, when acting under its CERCLA authority, and NRC, when a facility licensed by the NRC is undergoing decommissioning, or when a facility has completed decommissioning, and the NRC has terminated its license. EPA believes that implementation of the MOU between the two agencies will ensure that future confusion about dual regulation does not occur regarding the cleanup and reuse of NRC-licensed sites. NRC and EPA have so far exchanged MOU consultation letters on eight NRC-licensed sites. EPA has responded to each consultation request with a letter expressing its views on actions that NRC should consider that address the site-specific matter that triggered consultation. Over the course of consultations on the eight sites, there have been some reoccurring themes to EPA's views. Primarily, these are EPA: 1. Recommending that NRC consider selecting institutional controls to ensure that NRC's assumptions about future human exposure at the site are not exceeded. 2. Recommending that NRC consider using more site-specific information when conducting dose assessment modeling. 3. Recommending that NRC consider a flexible approach to groundwater protection that still ensures the public is not exposed to contamination levels over drinking water limits. 4. Recommending that NRC consider an approach similar to how EPA implements supplemental standards under 40 CFR 192 as an ARAR when the UMTRCA soil standard of 5 pCi/g is not being met.« less

75 FR 76953 - Reorganization of Foreign-Trade Zone 26 Under Alternative Site Framework, Atlanta, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

... Haralson, Paulding, Polk, Floyd, Bartow, Chattooga, Gordon, Pickens, Gilmer, Walker, Whitfield, Murray... the exception of Walker, Whitfield, and Murray Counties which are adjacent to the Chattanooga Customs...

40 CFR 60.2949 - What records must I keep?

Code of Federal Regulations, 2012 CFR

2012-07-01

..., malfunctioning, or out of control (except for downtime associated with zero and span and other routine... the types of waste burned during the test. (j) All documentation produced as a result of the siting...

40 CFR 60.2949 - What records must I keep?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., malfunctioning, or out of control (except for downtime associated with zero and span and other routine... the types of waste burned during the test. (j) All documentation produced as a result of the siting...

40 CFR 60.2949 - What records must I keep?

Code of Federal Regulations, 2011 CFR

2011-07-01

..., malfunctioning, or out of control (except for downtime associated with zero and span and other routine... the types of waste burned during the test. (j) All documentation produced as a result of the siting...

Quarterly environmental data summary for first quarter 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

In support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement, a copy of the Quarterly Environmental Data Summary (QEDS) for the first quarter of 1999 is enclosed. The data presented in this constitute the QEDS. The data, except for air monitoring data and site KPA generated data (uranium analyses), were received from the contract laboratories, verified by the Weldon Spring Site verification group and merged into the database during the first quarter of 1999. KPA results for on-site total uranium analyses performed during first quarter 1999 are included. Air monitoring data presented are the most recent completemore » sets of quarterly data.« less

Cattaraugus Creek Harbor, New York General Design Memorandum. Phase II. (Detailed Design). Volume II. Appendix E. Littoral Processes and Sedimentation in the Cattaraugus Embayment, New York. Appendix F. Sediment Transport in Cattaraugus Creek.

DTIC Science & Technology

1976-03-01

beaches than any other part of the southeastern shoreline of Lake Erie . It is the only major sand accumulation zone with the exception of Presque Isle , in...52 20. Photographs of zonal site #10. 54 21. Photograph and map of zonal site #11, Presque Isle , Pa. 57 F22. Photographs and beach profiles at zonal...site #11. 59 23. Photograph of zonal site #12, the recurved spit area on Presque Isle , Pa. 62 24. Block diagram of recurved spit area of Presque Isle

First principles study of electronic and structural properties of single walled zigzag boron nitride nanotubes doped with the elements of group IV

NASA Astrophysics Data System (ADS)

Bahari, Ali; jalalinejad, Amir; Bagheri, Mosahhar; Amiri, Masoud

2017-11-01

In this paper, structural and electronic properties and stability of (10, 0) born nitride nanotube (BNNT) are considered within density functional theory by doping group IV elements of the periodic table. The HOMO-LUMO gap has been strongly modified and treated a dual manner by choosing B or N sites for dopant atoms. Formation energy calculation shows that B site doping is more stable than N site doping. Results also show that all dopants turn the pristine BNNT into a p-type semiconductor except for carbon-doped BNNT at B site.

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival.

PubMed

Kim, Sangkyu; Welsh, David A; Myers, Leann; Cherry, Katie E; Wyckoff, Jennifer; Jazwinski, S Michal

2015-02-28

We have completed a genome-wide linkage scan for healthy aging using data collected from a family study, followed by fine-mapping by association in a separate population, the first such attempt reported. The family cohort consisted of parents of age 90 or above and their children ranging in age from 50 to 80. As a quantitative measure of healthy aging, we used a frailty index, called FI34, based on 34 health and function variables. The linkage scan found a single significant linkage peak on chromosome 12. Using an independent cohort of unrelated nonagenarians, we carried out a fine-scale association mapping of the region suggestive of linkage and identified three sites associated with healthy aging. These healthy-aging sites (HASs) are located in intergenic regions at 12q13-14. HAS-1 has been previously associated with multiple diseases, and an enhancer was recently mapped and experimentally validated within the site. HAS-2 is a previously uncharacterized site possessing genomic features suggestive of enhancer activity. HAS-3 contains features associated with Polycomb repression. The HASs also contain variants associated with exceptional longevity, based on a separate analysis. Our results provide insight into functional genomic networks involving non-coding regulatory elements that are involved in healthy aging and longevity.

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival

PubMed Central

Kim, Sangkyu; Welsh, David A.; Myers, Leann; Cherry, Katie E.; Wyckoff, Jennifer; Jazwinski, S. Michal

2015-01-01

We have completed a genome-wide linkage scan for healthy aging using data collected from a family study, followed by fine-mapping by association in a separate population, the first such attempt reported. The family cohort consisted of parents of age 90 or above and their children ranging in age from 50 to 80. As a quantitative measure of healthy aging, we used a frailty index, called FI34, based on 34 health and function variables. The linkage scan found a single significant linkage peak on chromosome 12. Using an independent cohort of unrelated nonagenarians, we carried out a fine-scale association mapping of the region suggestive of linkage and identified three sites associated with healthy aging. These healthy-aging sites (HASs) are located in intergenic regions at 12q13–14. HAS-1 has been previously associated with multiple diseases, and an enhancer was recently mapped and experimentally validated within the site. HAS-2 is a previously uncharacterized site possessing genomic features suggestive of enhancer activity. HAS-3 contains features associated with Polycomb repression. The HASs also contain variants associated with exceptional longevity, based on a separate analysis. Our results provide insight into functional genomic networks involving non-coding regulatory elements that are involved in healthy aging and longevity. PMID:25682868

7 CFR 1948.83 - Performance of site development work.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Performance of site development work. 1948.83 Section 1948.83 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... Development Assistance Program § 1948.83 Performance of site development work. Site development work will be...

49 CFR 397.7 - Parking.

Code of Federal Regulations, 2010 CFR

2010-10-01

... traveled portion of a public street or highway; (2) On private property (including premises of fueling or... bridge, tunnel, dwelling, or place where people work, congregate, or assemble, except for brief periods... public street or highway except for brief periods when the necessities of operation require the vehicle...

Geoheritage, Geodiversity and natural landscape enhanced and protected through anthropogenic activity: a case study using the Chaîne des Puys and Limagne Fault, Afar and Mexico City

NASA Astrophysics Data System (ADS)

van Wyk de Vries, Benjamin; Hagos, Miruts; Guilbaud, Marie-Noelle

2015-04-01

The UNESCO World Heritage (WH) committee called in 2014 for all thematic geological and volcanological studies to be revised in light of a widening gap between current dogma and the progressive geoheritage science views. We discuss question of natural sites and anthropogenic activity. The Chaîne des Puys and Limagne fault UNESCO WH project is the basis of this presentation, but we also the Afar Region of Ethiopia and UNAM campus, Mexico City. It is now difficult to find any totally 'natural' (devoid of human influence) landscape. This very definition of natural ignores that humankind is a geological force, and humans are part of the natural process. The UNESCO WH guidelines recognise this in paragraph 90: 'it is recognized that no area is totally pristine and that all natural areas are in a dynamic state, and to some extent involve contact with people'. A geological landscape, may be large enough to accommodate human occupation without significantly changing landforms: this is the case of the Chaîne des Puys and Limagne fault. Human activity works in some ways to protect geological landscape: regulating vegetation and erosion. The aesthetic nature of humans may work to enhance the landscape's visibility by organisation of land use, and ceremonial use based on the sense of place. Humans also exercise economic activity such as quarrying and mining, which if uncontrolled can seriously modify a landscape. However, isolated works may not have an impact, or may even enhance the value of the site by uncovering geological features that would not naturally be seen. In the Chaîne des Puys only 0,3% of the land surface has been worked by artisanal methods and certain sites, like the Lemptégy volcano have been extracted with the view of enhancing the landscape's scientific value without detracting from the aesthetic. The site preserves its natural, scientific and aesthetic qualities, because of the human presence. The local population have always been and continue to be the guardians of the exceptional universal value of the site. The Afar is an example of anthropogenic influence on a natural site, where traditional salt extraction has no impact on a natural site constantly renewed by the environmental activity renews the landscape. Introducing modern usage however requires greater levels of protection, and closer monitoring. UNAM campus is urban, but small pockets of superbly preserved lava from the Xitle volcano provide an opportunity to observe an important natural hazard in the heart of the city. This example shows how resistant natural features are at a small scale. In conclusion, it is clear that anthropogenic influences on landscape are omnipresent and the definition of natural landscape as devoid of any human presence has little meaning. Human activity needs to be acknowledged to be an essential part of geodiversity. The current revisions called for by UNESCO ask the geoscience community to take a greater part in this process, and our community should use this opportunity to make a stronger impact in the world heritage process.

High-pressure synthesis, crystal chemistry and physics of perovskites with small cations at the A site.

PubMed

Belik, Alexei A; Yi, Wei

2014-04-23

ABO3 perovskites with small cations at the A site (A = Sc(3+), In(3+) and Mn(2+) and B = Al(3+) and transition metals) are reviewed. They extend the corresponding families of perovskites with A(3+) = Y, La-Lu, and Bi and A(2+) = Cd, Ca, Sr and Ba and exhibit the largest structural distortions. As a result of these large distortions, they show, in many cases, distinct structural and magnetic properties. These are manifested in: B-site-ordered monoclinic structures of ScMnO3 and 'InMnO3'; an unusual superstructure of ScRhO3 and InRhO3; antiferromagnetic ground states and multiferroic properties of Sc2NiMnO6 and In2NiMnO6; two magnetic transitions in ScCrO3 and InCrO3 with very close transition temperatures; a Pnma-to-P-1 structural transition and k = (½, 0, ½) magnetic ordering in ScVO3; and incommensurate magnetic ordering of Mn(2+) spins in metallic MnVO3. A large number of simple ScBO3, InBO3 and MnBO3 perovskites has not been synthesized yet, and the number of experimental and theoretical works on each known ScBO3, InBO3 and MnBO3 perovskites counts to only one or two (except for ScAlO3). The synthesis, crystal chemistry and physics of perovskites with small cations at the A site is an emerging field in perovskite science.

Biomimetic Chemistry of Iron, Nickel, Molybdenum, and Tungsten in Sulfur-Ligated Protein Sites†

PubMed Central

Groysman, Stanislav; Holm, R. H.

2009-01-01

Biomimetic inorganic chemistry has as its primary goal the synthesis of molecules that approach or achieve the structures, oxidation states, and electronic and reactivity features of native metal-containing sites of variant nuclearity. Comparison of properties of accurate analogues and these sites ideally provides insight into the influence of protein structure and environment on intrinsic properties as represented by the analogue. For polynuclear sites in particular, the goal provides a formidable challenge for, with the exception of iron-sulfur clusters, all such site structures have never been achieved and few even closely approximated by chemical synthesis. This account describes the current status of the synthetic analogue approach as applied to the mononuclear sites in certain molybdoenzymes and the polynuclear sites in hydrogenases, nitrogenase, and carbon monoxide dehydrogenases. PMID:19206188

[The Rosenthal experiment or: about the site of productive research - on move of the physiological experimental laboratory of Isidor Rosenthal (1836-1915) from the city to the country].

PubMed

Stahnisch, Frank W

2010-01-01

The disciplinary development of the new science of experimental physiology is often associated with the conditions of cultural development and increasingly technical working contexts of the Industrial Age. Following this perspective, the germ cells of 19th century institutes of experimental physiology were particularly found in the metropolises of Paris, Leipzig or Berlin. Only the major cities sat the revolutionary trends and within this general process, the scientific trends were no exceptions - the provincial research universities simply followed the central ones in their normal science endeavours. Due to this interpretation, the development of the scientific community was pre-formatted as the interplay of innovation (the city) and reception (the periphery). Isidor Rosenthal (1836-1915) was born in Labischin (District of Bromberg/Posen) in 1836 and got his medical training in Berlin. Like not many other experimental physiologists, he can be used as a historiographical testing probe, to follow the conditions of knowledge transfer from center to periphery: After his studies at the Friedrich Wilhelms University and the completion of his dissertation in 1859, Rosenthal entered the newly founded Physiological Institute in Berlin as the first Research Associate of Emil DuBois-Reymond (1818-1896). Rosenthal worked here particularly on the problem of "direct and indirect muscle irritation" in frogs. These neurophysiological investigations led to his growing scientific renown. In 1872, Rosenthal became offered a first professorship in physiology at the Friedrich Alexander University in Bavaria, as one of only few Jewish scientists (and even before Wilhelm Wundt, 1832-1920). But his life and work proved not only exceptional because of his scientific achievements, but also due to his deep rootedness in cultural life--both during his time in Berlin and in Erlangen. By applying a comparative and microhistorical approach in this article, the working conditions of this scientific migrant from Berlin are scrutinized as to the changes that took place between the city and regional university.

Evaluation of acidity estimation methods for mine drainage, Pennsylvania, USA.

PubMed

Park, Daeryong; Park, Byungtae; Mendinsky, Justin J; Paksuchon, Benjaphon; Suhataikul, Ratda; Dempsey, Brian A; Cho, Yunchul

2015-01-01

Eighteen sites impacted by abandoned mine drainage (AMD) in Pennsylvania were sampled and measured for pH, acidity, alkalinity, metal ions, and sulfate. This study compared the accuracy of four acidity calculation methods with measured hot peroxide acidity and identified the most accurate calculation method for each site as a function of pH and sulfate concentration. Method E1 was the sum of proton and acidity based on total metal concentrations; method E2 added alkalinity; method E3 also accounted for aluminum speciation and temperature effects; and method E4 accounted for sulfate speciation. To evaluate errors between measured and predicted acidity, the Nash-Sutcliffe efficiency (NSE), the coefficient of determination (R (2)), and the root mean square error to standard deviation ratio (RSR) methods were applied. The error evaluation results show that E1, E2, E3, and E4 sites were most accurate at 0, 9, 4, and 5 of the sites, respectively. Sites where E2 was most accurate had pH greater than 4.0 and less than 400 mg/L of sulfate. Sites where E3 was most accurate had pH greater than 4.0 and sulfate greater than 400 mg/L with two exceptions. Sites where E4 was most accurate had pH less than 4.0 and more than 400 mg/L sulfate with one exception. The results indicate that acidity in AMD-affected streams can be accurately predicted by using pH, alkalinity, sulfate, Fe(II), Mn(II), and Al(III) concentrations in one or more of the identified equations, and that the appropriate equation for prediction can be selected based on pH and sulfate concentration.

36 CFR 261.16 - Developed recreation sites.

Code of Federal Regulations, 2012 CFR

2012-07-01

... animal, other than a service animal, unless it is crated, caged, or upon a leash not longer than six feet... animal, other than a service animal. (l) Bringing in or possessing a saddle, pack, or draft animal except...

36 CFR 261.16 - Developed recreation sites.

Code of Federal Regulations, 2014 CFR

2014-07-01

... animal, other than a service animal, unless it is crated, caged, or upon a leash not longer than six feet... animal, other than a service animal. (l) Bringing in or possessing a saddle, pack, or draft animal except...

Impact of refined petroleum spills on water quality, macro-invertebrate and microbial communities of a tropical aquatic environment.

PubMed

Chukwu, L O; Nwachukwu, S C U

2005-07-01

Water quality characteristics, benthic macro-invertebrates and microbial communities of three first order streams in South West Nigeria were investigated to assess the effects of refined petroleum five months after spillage. All physical and chemical conditions except temperature and pH were significantly different (P<0.01) at the upstream control stations and impacted stations reflecting the perturbational stress. The benthic macro-invertebrate fauna were dominated by arthropods, but the faunal spectrum was dissimilar at all the stations studied. Sampling stations at the epicentre of the spill showed considerable reduction in faunal compositions and relative abundance. Generally, the microbial density and diversity were highest in both soil and water samples from impacted sites than in control sites. There was a significantly higher proportion (P < 0.05) of hydrocarbon utilizers in soil than in water samples in all stations except in samples from stations (P<0.05).

29 CFR 785.12 - Work performed away from the premises or job site.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Work performed away from the premises or job site. 785.12... of Principles Employees âsuffered Or Permittedâ to Work § 785.12 Work performed away from the premises or job site. The rule is also applicable to work performed away from the premises or the job site...

76 FR 38389 - Caraleigh Phosphate and Fertlizer Works Superfund Site; Raleigh, Wake County, NC; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-30

... and Fertlizer Works Superfund Site; Raleigh, Wake County, NC; Notice of Settlement AGENCY... Caraleigh Phosphate and Fertilizer Works Superfund Site located in Raleigh, Wake County, North Carolina for... Phosphate and Fertilizer Works Superfund Site by one of the following methods: http://www.regulations.gov...

Effects of Stress and Task Difficulty on Working Memory and Cortical Networking.

PubMed

Kim, Yujin; Woo, Jihwan; Woo, Minjung

2017-12-01

This study investigated interactive effects of stress and task difficulty on working memory and cortico-cortical communication during memory encoding. Thirty-eight adolescent participants (mean age of 15.7 ± 1.5 years) completed easy and hard working memory tasks under low- and high-stress conditions. We analyzed the accuracy and reaction time (RT) of working memory performance and inter- and intrahemispheric electroencephalogram coherences during memory encoding. Working memory accuracy was higher, and RT shorter, in the easy versus the hard task. RT was shorter under the high-stress (TENS) versus low-stress (no-TENS) condition, while there was no difference in memory accuracy between the two stress conditions. For electroencephalogram coherence, we found higher interhemispheric coherence in all bands but only at frontal electrode sites in the easy versus the hard task. On the other hand, intrahemispheric coherence was higher in the left hemisphere in the easy (versus hard task) and higher in the right hemisphere (with one exception) in the hard (versus easy task). Inter- and intracoherences were higher in the low- versus high-stress condition. Significant interactions between task difficulty and stress condition were observed in coherences of the beta frequency band. The difference in coherence between low- and high-stress conditions was greater in the hard compared with the easy task, with lower coherence under the high-stress condition relative to the low-stress condition. Stress seemed to cause a decrease in cortical network communications between memory-relevant cortical areas as task difficulty increased.

Site-selective and stereoselective functionalization of non-activated tertiary C-H bonds

NASA Astrophysics Data System (ADS)

Liao, Kuangbiao; Pickel, Thomas C.; Boyarskikh, Vyacheslav; Bacsa, John; Musaev, Djamaladdin G.; Davies, Huw M. L.

2017-11-01

The synthesis of complex organic compounds usually relies on controlling the reactions of the functional groups. In recent years, it has become possible to carry out reactions directly on the C-H bonds, previously considered to be unreactive. One of the major challenges is to control the site-selectivity because most organic compounds have many similar C-H bonds. The most well developed procedures so far rely on the use of substrate control, in which the substrate has one inherently more reactive C-H bond or contains a directing group or the reaction is conducted intramolecularly so that a specific C-H bond is favoured. A more versatile but more challenging approach is to use catalysts to control which site in the substrate is functionalized. p450 enzymes exhibit C-H oxidation site-selectivity, in which the enzyme scaffold causes a specific C-H bond to be functionalized by placing it close to the iron-oxo haem complex. Several studies have aimed to emulate this enzymatic site-selectivity with designed transition-metal catalysts but it is difficult to achieve exceptionally high levels of site-selectivity. Recently, we reported a dirhodium catalyst for the site-selective functionalization of the most accessible non-activated (that is, not next to a functional group) secondary C-H bonds by means of rhodium-carbene-induced C-H insertion. Here we describe another dirhodium catalyst that has a very different reactivity profile. Instead of the secondary C-H bond, the new catalyst is capable of precise site-selectivity at the most accessible tertiary C-H bonds. Using this catalyst, we modify several natural products, including steroids and a vitamin E derivative, indicating the applicability of this method of synthesis to the late-stage functionalization of complex molecules. These studies show it is possible to achieve site-selectivity at different positions within a substrate simply by selecting the appropriate catalyst. We hope that this work will inspire the design of even more sophisticated catalysts, such that catalyst-controlled C-H functionalization becomes a broadly applied strategy for the synthesis of complex molecules.

20 CFR 10.400 - What is total disability?

Code of Federal Regulations, 2010 CFR

2010-04-01

..., such as evidence of continued ability to work and to earn wages despite the loss. (b) Temporary total... equivalent wages, or to perform other gainful employment, due to the work-related injury. Except as presumed... pending return to work. ...

20 CFR 10.400 - What is total disability?

Code of Federal Regulations, 2011 CFR

2011-04-01

..., such as evidence of continued ability to work and to earn wages despite the loss. (b) Temporary total... equivalent wages, or to perform other gainful employment, due to the work-related injury. Except as presumed... pending return to work. ...

29 CFR 1915.94 - Work in confined or isolated spaces.

Code of Federal Regulations, 2011 CFR

2011-07-01

... apply to ship repairing, shipbuilding and shipbreaking. When any work is performed in a confined space, except as provided in § 1915.51(c)(3), or when an employee is working alone in an isolated location...

Statistical Patterns in Movie Rating Behavior

PubMed Central

2015-01-01

Currently, users and consumers can review and rate products through online services, which provide huge databases that can be used to explore people’s preferences and unveil behavioral patterns. In this work, we investigate patterns in movie ratings, considering IMDb (the Internet Movie Database), a highly visited site worldwide, as a source. We find that the distribution of votes presents scale-free behavior over several orders of magnitude, with an exponent very close to 3/2, with exponential cutoff. It is remarkable that this pattern emerges independently of movie attributes such as average rating, age and genre, with the exception of a few genres and of high-budget films. These results point to a very general underlying mechanism for the propagation of adoption across potential audiences that is independent of the intrinsic features of a movie and that can be understood through a simple spreading model with mean-field avalanche dynamics. PMID:26322899

Statistical Patterns in Movie Rating Behavior.

PubMed

Ramos, Marlon; Calvão, Angelo M; Anteneodo, Celia

2015-01-01

Currently, users and consumers can review and rate products through online services, which provide huge databases that can be used to explore people's preferences and unveil behavioral patterns. In this work, we investigate patterns in movie ratings, considering IMDb (the Internet Movie Database), a highly visited site worldwide, as a source. We find that the distribution of votes presents scale-free behavior over several orders of magnitude, with an exponent very close to 3/2, with exponential cutoff. It is remarkable that this pattern emerges independently of movie attributes such as average rating, age and genre, with the exception of a few genres and of high-budget films. These results point to a very general underlying mechanism for the propagation of adoption across potential audiences that is independent of the intrinsic features of a movie and that can be understood through a simple spreading model with mean-field avalanche dynamics.

Complete characterization of the seventeen step moenomycin biosynthetic pathway

PubMed Central

Ostash, Bohdan; Doud, Emma; Lin, Cecilie; Ostash, Iryna; Perlstein, Deborah; Fuse, Shinichiro; Wolpert, Manuel; Kahne, Daniel; Walker, Suzanne

2009-01-01

The moenomycins are phosphoglycolipid antibiotics produced by Streptomyces ghanaensis and related organisms. The phosphoglycolipids are the only known active site inhibitors of the peptidoglycan glycosyltransferases, an important family of enzymes involved in the biosynthesis of the bacterial cell wall. Although these natural products have exceptionally potent antibiotic activity, pharmacokinetic limitations have precluded their clinical use. We previously identified the moenomycin biosynthetic gene cluster in order to facilitate biosynthetic approaches to new derivatives. Here we report a comprehensive set of genetic and enzymatic experiments that establish functions for the seventeen moenomycin biosynthetic genes involved in the synthesis moenomycin and variants. These studies reveal the order of assembly of the full molecular scaffold and define a subset of seven genes involved in the synthesis of bioactive analogs. This work will enable both in vitro and fermentation-based reconstitution of phosphoglycolipid scaffolds so that chemoenzymatic approaches to novel analogs can be explored. PMID:19640006

Loads and yields of selected constituents in streams and rivers of Monroe County, New York, 1984-2001

USGS Publications Warehouse

Sherwood, Donald A.

2004-01-01

Hydrologic data collected in Monroe County since the 1980s and earlier, including long-term records of streamflow and chemical loads, provide a basis for assessment of water-management practices. All monitored streams except Northrup Creek showed a slight (nonsignificant) overall decrease in annual streamflow over their period of record; Northrup Creek showed a slight increase.The highest yields of all constituents except chloride and sulfate were at Northrup Creek; these values exceeded those of the seven Irondequoit Creek basin sites and the Genesee River site. The highest yields of dissolved chloride were at the most highly urbanized site (Allen Creek), whereas the highest yields of dissolved sulfate were at the most upstream Irondequoit Creek sites -- Railroad Mills (active) and Pittsford (inactive). Yields of all constituents in the Genesee River at the Charlotte Pump Station were within the range of those at the Irondequoit Creek basin sites.The four active Irondequoit Creek basin sites showed significant downward trends in flow-adjusted loads of ammonia + organic nitrogen, possibly from the conversion of agricultural land to suburban land. Two active sites (Allen Creek and Blossom Road) and one inactive site (Thomas Creek) showed downward trends in loads of ammonia. All active sites showed significant upward trends in dissolved chloride loads. Northrup Creek showed a significant downward trend in total phosphorus load since the improvement in phosphorus removal at the Spencerport wastewater-treatment plant, and upward trends in dissolved chloride and sulfate loads. The Genesee River at the Charlotte Pump Station showed significant downward trends in loads of ammonia + organic nitrogen and chloride, and an upward trend in loads of orthophosphate.The improved treatment or diversion of sewage-treatment-plant-effluent has produced decreased yields of some constituents throughout the county, particularly in the Irondequoit Creek basin, where the loads of nutrients delivered to Irondequoit Bay have been decreased.

30 CFR 77.103 - Electrical work; qualified person.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electrical work; qualified person. 77.103... COAL MINES Qualified and Certified Persons § 77.103 Electrical work; qualified person. (a) Except as... Subparts F, G, H, I, and J of this Part 77 to perform electrical work (other than work on energized surface...

30 CFR 77.103 - Electrical work; qualified person.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electrical work; qualified person. 77.103... COAL MINES Qualified and Certified Persons § 77.103 Electrical work; qualified person. (a) Except as... Subparts F, G, H, I, and J of this Part 77 to perform electrical work (other than work on energized surface...

30 CFR 77.103 - Electrical work; qualified person.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electrical work; qualified person. 77.103... COAL MINES Qualified and Certified Persons § 77.103 Electrical work; qualified person. (a) Except as... Subparts F, G, H, I, and J of this Part 77 to perform electrical work (other than work on energized surface...

Shifting Paradigms to Better Serve Twice-Exceptional African-American Learners

ERIC Educational Resources Information Center

Owens, Charissa M.; Ford, Donna Y.; Lisbon, April J.; Owens, Michael T.

2016-01-01

Existing research on students with twice-exceptional abilities concentrates on strategies to improve the educational experiences of individuals who demonstrate the comorbid presence of a talent for high academic achievement (often considered a strength) and a disability (often considered a weakness). However, this body of work typically excludes…

Working with Twice-Exceptional African American Students: Information for School Counselors

ERIC Educational Resources Information Center

Mayes, Renae D.; Hines, Erik M.; Harris, Paul C.

2014-01-01

This qualitative study examined the perceptions, attitudes, and experiences of eight twice-exceptional African American gifted students who attended the same K-12 urban school district in the Midwest. Four major themes emerged--academic supports, personal and social challenges, career worries, and experience with school counselors. Findings…

29 CFR 1926.500 - Scope, application, and definitions applicable to this subpart.

Code of Federal Regulations, 2012 CFR

2012-07-01

... protection requirements for employees performing steel erection work (except for towers and tanks) are... protection systems, except in relation to steel erection activities and the use of equipment covered by... refusal, breakage, or separation of component parts. Load refusal is the point where the ultimate strength...

29 CFR 1926.500 - Scope, application, and definitions applicable to this subpart.

Code of Federal Regulations, 2011 CFR

2011-07-01

... protection requirements for employees performing steel erection work (except for towers and tanks) are... protection systems, except in relation to steel erection activities and the use of equipment covered by... refusal, breakage, or separation of component parts. Load refusal is the point where the ultimate strength...

29 CFR 1926.500 - Scope, application, and definitions applicable to this subpart.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Fall protection requirements for employees performing steel erection work (except for towers and tanks... protection systems, except in relation to steel erection activities. (b) Definitions. Anchorage means a... component parts. Load refusal is the point where the ultimate strength is exceeded. Free fall means the act...

29 CFR 1926.500 - Scope, application, and definitions applicable to this subpart.

Code of Federal Regulations, 2013 CFR

2013-07-01

... protection requirements for employees performing steel erection work (except for towers and tanks) are... protection systems, except in relation to steel erection activities and the use of equipment covered by... refusal, breakage, or separation of component parts. Load refusal is the point where the ultimate strength...

FAPE Model of Exceptional Student Education Leadership

ERIC Educational Resources Information Center

Dubberly, Russell G.

2012-01-01

The FAPE Model of Exceptional Education Leadership is defined as facilitative, affiliative, praising and rewarding, and experiential and empirical. The FAPE administrator uses a facilitative approach that guides and coaches to help employees find a pathway to success. This leader works to build emotional capacity between all members of the…

76 FR 25588 - Hours of Service Exception for Railroad Signal Employees

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... ID. FMCSA-2010-0032] RIN 2126-AB36 Hours of Service Exception for Railroad Signal Employees AGENCY... language consistent with the statutory exemption for certain railroad signal employees operating commercial motor vehicles (CMVs) in connection with railroad signal work. This is in accordance with the Rail...

Counseling Exceptional Individuals and Their Families: A Systems Perspective

ERIC Educational Resources Information Center

Thomas, Volker; Ray, Karen E.

2006-01-01

This article presents three models of counseling exceptional students from a systems perspective. The authors present their definition of counseling, the goals of counseling, and the counseling relationship from a systems perspective. Each model is described, including assessment and intervention techniques appropriate for working with children,…

Music Instruction for Elementary Students with Moderate to Severe Cognitive Impairments: A Case Study

ERIC Educational Resources Information Center

Salvador, Karen

2015-01-01

Although elementary general music specialists teach students with a variety of exceptionalities every day (Chen, 2007; Hahn, 2010; Hoffman, 2011), many music teacher preparation programs do not adequately address exceptionality (Salvador, 2010). Articles regarding "strategies that work" appear perennially in the professional literature…

Safety evaluation for packaging (onsite) concrete-lined waste packaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romano, T.

1997-09-25

The Pacific Northwest National Laboratory developed a package to ship Type A, non-transuranic, fissile excepted quantities of liquid or solid radioactive material and radioactive mixed waste to the Central Waste Complex for storage on the Hanford Site.

Comparing satisfaction and burnout between caseload and standard care midwives: findings from two cross-sectional surveys conducted in Victoria, Australia.

PubMed

Newton, Michelle S; McLachlan, Helen L; Willis, Karen F; Forster, Della A

2014-12-24

Caseload midwifery reduces childbirth interventions and increases women's satisfaction with care. It is therefore important to understand the impact of caseload midwifery on midwives working in and alongside the model. While some studies have reported higher satisfaction for caseload compared with standard care midwives, others have suggested a need to explore midwives' work-life balance as well as potential for stress and burnout. This study explored midwives' attitudes to their professional role, and also measured burnout in caseload midwives compared to standard care midwives at two sites in Victoria, Australia with newly introduced caseload midwifery models. All midwives providing maternity care at the study sites were sent questionnaires at the commencement of the caseload midwifery model and two years later. Data items included the Midwifery Process Questionnaire (MPQ) to examine midwives' attitude to their professional role, the Copenhagen Burnout Inventory (CBI) to measure burnout, and questions about midwives' views of caseload work. Data were pooled for the two sites and comparisons made between caseload and standard care midwives. The MPQ and CBI data were summarised as individual and group means. Twenty caseload midwives (88%) and 130 standard care midwives (41%) responded at baseline and 22 caseload midwives (95%) and 133 standard care midwives (45%) at two years. Caseload and standard care midwives were initially similar across all measures except client-related burnout, which was lower for caseload midwives (12.3 vs 22.4, p = 0.02). After two years, compared to midwives in standard care, caseload midwives had higher mean scores in professional satisfaction (1.08 vs 0.76, p = 0.01), professional support (1.06 vs 0.11, p <0.01) and client interaction (1.4 vs 0.09, p <0.01) and lower scores for personal burnout (35.7 vs 47.7, p < 0.01), work-related burnout (27.3 vs 42.7, p <0.01), and client-related burnout (11.3 vs 21.4, p < 0.01). Caseload midwifery was associated with lower burnout scores and higher professional satisfaction. Further research should focus on understanding the key features of the caseload model that are related to these outcomes to help build a picture of what is required to ensure the long-term sustainability of the model.

Remediation System Evaluation, American Creosote Works Site, Pensacola, Florida

EPA Pesticide Factsheets

The American Creosote Works (ACW) site is located on 1800 Gimble Street on the abandoned AmericanCreosote Works wood preserving plant in Pensacola, Florida. The site is approximately 18 acres in area.The site is about 600 yards north of Pensacola Bay..

Identification of Late Eocene Impact Deposits at ODP Site 1090

NASA Technical Reports Server (NTRS)

Kyte, Frank T.

2001-01-01

Anomalous concentrations of Ir have been found in upper Eocene sediments from Ocean Drilling Program (ODP) Hole 1090B. Clear and dark-colored spherules that are believed to be microtektites and clinopyroxene- bearing microkrystites, respectively, were found in the samples with highest Ir. The peak Ir concentration in Sample 177- 1090B-30X-5,105-106 cm (954 pg/g) and the net Ir fluence (14 ng/cm2) at this site are higher that at most other localities except for Caribbean site RC9-58. The Ir anomaly and impact debris are probably correlative with similar deposits found at ODP Site 689 on the Maude Rise and at other localities around the world.

Novel Autophosphorylation Sites of Src Family Kinases Regulate Kinase Activity and SH2 Domain Binding Capacity

PubMed Central

Weir, Marion E.; Mann, Jacqueline E.; Corwin, Thomas; Fulton, Zachary W.; Hao, Jennifer M.; Maniscalco, Jeanine F.; Kenney, Marie C.; Roque, Kristal M. Roman; Chapdelaine, Elizabeth F.; Stelzl, Ulrich; Deming, Paula B.; Ballif, Bryan A.; Hinkle, Karen L.

2016-01-01

Src family tyrosine kinases (SFKs) are critical players in normal and aberrant biological processes. While phosphorylation importantly-regulates SFKs at two known tyrosines, large-scale phosphoproteomics have revealed four additional tyrosines commonly-phosphorylated in SFKs. We found these novel tyrosines to be autophosphorylation sites. Mimicking phosphorylation at the site C-terminal to the activation loop decreased Fyn activity. Phosphomimetics and direct phosphorylation at the three SH2 domain sites increased Fyn activity while reducing phosphotyrosine-dependent interactions. While 68% of human SH2 domains exhibit conservation of at least one of these tyrosines, few have been found phosphorylated except when found in cis to a kinase domain. PMID:27001024

20 CFR 617.17 - Availability and active search for work.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Availability and active search for work. 617.17 Section 617.17 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR...) § 617.17 Availability and active search for work. (a) Extended Benefit work test applicable. Except as...

20 CFR 617.17 - Availability and active search for work.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Availability and active search for work. 617.17 Section 617.17 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR...) § 617.17 Availability and active search for work. (a) Extended Benefit work test applicable. Except as...

20 CFR 617.17 - Availability and active search for work.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Availability and active search for work. 617.17 Section 617.17 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR...) § 617.17 Availability and active search for work. (a) Extended Benefit work test applicable. Except as...

20 CFR 617.17 - Availability and active search for work.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false Availability and active search for work. 617.17 Section 617.17 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR...) § 617.17 Availability and active search for work. (a) Extended Benefit work test applicable. Except as...

20 CFR 617.17 - Availability and active search for work.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false Availability and active search for work. 617.17 Section 617.17 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR...) § 617.17 Availability and active search for work. (a) Extended Benefit work test applicable. Except as...

30 CFR 77.103 - Electrical work; qualified person.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electrical work; qualified person. 77.103... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Qualified and Certified Persons § 77.103 Electrical work; qualified person. (a) Except as...

30 CFR 77.103 - Electrical work; qualified person.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electrical work; qualified person. 77.103... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Qualified and Certified Persons § 77.103 Electrical work; qualified person. (a) Except as...

29 CFR 1904.5 - Determination of work-relatedness.

Code of Federal Regulations, 2013 CFR

2013-07-01

... one or more employees are working or are present as a condition of their employment. The work... environment that falls under one of the following exceptions is not work-related, and therefore is not... shot, exercise class, racquetball, or baseball. (iv) The injury or illness is solely the result of an...

29 CFR 1904.5 - Determination of work-relatedness.

Code of Federal Regulations, 2012 CFR

2012-07-01

... one or more employees are working or are present as a condition of their employment. The work... environment that falls under one of the following exceptions is not work-related, and therefore is not... shot, exercise class, racquetball, or baseball. (iv) The injury or illness is solely the result of an...

29 CFR 1904.5 - Determination of work-relatedness.

Code of Federal Regulations, 2010 CFR

2010-07-01

... one or more employees are working or are present as a condition of their employment. The work... environment that falls under one of the following exceptions is not work-related, and therefore is not... shot, exercise class, racquetball, or baseball. (iv) The injury or illness is solely the result of an...

29 CFR 1904.5 - Determination of work-relatedness.

Code of Federal Regulations, 2011 CFR

2011-07-01

... one or more employees are working or are present as a condition of their employment. The work... environment that falls under one of the following exceptions is not work-related, and therefore is not... shot, exercise class, racquetball, or baseball. (iv) The injury or illness is solely the result of an...

29 CFR 1904.5 - Determination of work-relatedness.

Code of Federal Regulations, 2014 CFR

2014-07-01

... one or more employees are working or are present as a condition of their employment. The work... environment that falls under one of the following exceptions is not work-related, and therefore is not... shot, exercise class, racquetball, or baseball. (iv) The injury or illness is solely the result of an...

In silico designing of hyper-glycosylated analogs for the human coagulation factor IX.

PubMed

Ghasemi, Fahimeh; Zomorodipour, Alireza; Karkhane, Ali Asghar; Khorramizadeh, M Reza

2016-07-01

N-glycosylation is a process during which a glycan moiety attaches to the asparagine residue in the N-glycosylation consensus sequence (Asn-Xxx-Ser/Thr), where Xxx can be any amino acid except proline. Introduction of a new N-glycosylation site into a protein backbone leads to its hyper-glycosylation, and may improve the protein properties such as solubility, folding, stability, and secretion. Glyco-engineering is an approach to facilitate the hyper-glycosylation of recombinant proteins by application of the site-directed mutagenesis methods. In this regard, selection of a suitable location on the surface of a protein for introduction of a new N-glycosylation site is a main concern. In this work, a computational approach was conducted to select suitable location(s) for introducing new N-glycosylation sites into the human coagulation factor IX (hFIX). With this aim, the first 45 residues of mature hFIX were explored to find out suitable positions for introducing either Asn or Ser/Thr residues, to create new N-glycosylation site(s). Our exploration lead to detection of five potential positions, for hyper-glycosylation. For each suggested position, an analog was defined and subjected for N-glycosylation efficiency prediction. After generation of three-dimensional structures, by homology-based modeling, the five designed analogs were examined by molecular dynamic (MD) simulations, to predict their stability levels and probable structural distortions caused by amino acid substitutions, relative to the native counterpart. Three out of five suggested analogs, namely; E15T, K22N, and R37N, reached equilibration state with relatively constant Root Mean Square Deviation values. Additional analysis on the data obtained during MD simulations, lead us to conclude that, R37N is the only qualified analog with the most similar structure and dynamic behavior to that of the native counterpart, to be considered for further experimental investigations. Copyright © 2016 Elsevier Inc. All rights reserved.

Exposure chain of urban air PM 2.5—associations between ambient fixed site, residential outdoor, indoor, workplace and personal exposures in four European cities in the EXPOLIS-study

NASA Astrophysics Data System (ADS)

Kousa, Anu; Oglesby, Lucy; Koistinen, Kimmo; Künzli, Nino; Jantunen, Matti

In the EXPOLIS study personal exposures and microenvironment levels of air pollutants from 50-201 urban adult (25-55 yr) participants were measured in six European cities during 1 yr from autumn 1996 to winter 1997-98. This paper presents the associations between the personal PM 2.5 exposures, microenvironment (residential indoor, residential outdoor and workplace indoor) and ambient fixed site concentrations measured in Helsinki (Finland), Basel (Switzerland), Prague (Czech Republic) and Athens (Greece). Considering the whole chain from ambient fixed site to residential outdoor, residential indoor and personal leisure time (non-working hours) exposure, the correlations were highest between personal leisure time exposures and residential indoor concentrations (non-environmental tobacco smoke (ETS): Pearson r=0.72-0.92, ETS included: r=0.82-0.86) except in Athens, where the correlation between residential indoor and outdoor air was highest (non-ETS: r=0.82, ETS included: r=0.68)). Unfortunately, ambient fixed site PM 2.5 concentrations were measured continuously only in Helsinki. Ambient fixed site PM 2.5 concentrations correlated quite well with residential outdoor concentrations ( r=0.90), and also with residential indoor (non-ETS) concentrations ( r=0.80), but concentrations measured at ambient fixed site monitors were poor predictors of personal exposures to PM 2.5. They were particularly poor predictors of personal workday exposures (non-ETS: r=0.34, ETS included: r=0.25), but considerably better for personal leisure time exposures (non-ETS: r=0.69, ETS included: r=0.54). According to log-linear regression models combined from all centres of non-ETS-exposed participants, residential indoor concentrations explained 76% of personal leisure time PM 2.5 exposure variation and workplace indoor concentrations explained 66% of the workday exposure variation.

Three sympatric clusters of the malaria vector Anopheles culicifacies E (Diptera: Culicidae) detected in Sri Lanka.

PubMed

Harischandra, Iresha Nilmini; Dassanayake, Ranil Samantha; De Silva, Bambaranda Gammacharige Don Nissanka Kolitha

2016-01-04

The disease re-emergence threat from the major malaria vector in Sri Lanka, Anopheles culicifacies, is currently increasing. To predict malaria vector dynamics, knowledge of population genetics and gene flow is required, but this information is unavailable for Sri Lanka. This study was carried out to determine the population structure of An. culicifacies E in Sri Lanka. Eight microsatellite markers were used to examine An. culicifacies E collected from six sites in Sri Lanka during 2010-2012. Standard population genetic tests and analyses, genetic differentiation, Hardy-Weinberg equilibrium, linkage disequilibrium, Bayesian cluster analysis, AMOVA, SAMOVA and isolation-by-distance were conducted using five polymorphic loci. Five microsatellite loci were highly polymorphic with high allelic richness. Hardy-Weinberg Equilibrium (HWE) was significantly rejected for four loci with positive F(IS) values in the pooled population (p < 0.0100). Three loci showed high deviations in all sites except Kataragama, which was in agreement with HWE for all loci except one locus (p < 0.0016). Observed heterozygosity was less than the expected values for all sites except Kataragama, where reported negative F(IS) values indicated a heterozygosity excess. Genetic differentiation was observed for all sampling site pairs and was not supported by the isolation by distance model. Bayesian clustering analysis identified the presence of three sympatric clusters (gene pools) in the studied population. Significant genetic differentiation was detected in cluster pairs with low gene flow and isolation by distance was not detected between clusters. Furthermore, the results suggested the presence of a barrier to gene flow that divided the populations into two parts with the central hill region of Sri Lanka as the dividing line. Three sympatric clusters were detected among An. culicifacies E specimens isolated in Sri Lanka. There was no effect of geographic distance on genetic differentiation and the central mountain ranges in Sri Lanka appeared to be a barrier to gene flow.

On-site infiltration of road runoff using pervious pavements with subjacent infiltration trenches as source control strategy.

PubMed

Fach, S; Dierkes, C

2011-01-01

The focus in this work was on subsoil infiltration of stormwater from parking lots. With regard to operation, reduced infiltration performance due to clogging and pollutants in seepage, which may contribute to contaminate groundwater, are of interest. The experimental investigation covered a pervious pavement with a subjacent infiltration trench draining an impervious area of 2 ha. In order to consider seasonal effects on the infiltration performance, the hydraulic conductivity was measured tri-monthly during monitoring with a mobile sprinkling unit. To assess natural deposits jointing, road bed, gravel of infiltration trenches and subsoil were analysed prior to commencement of monitoring for heavy metals, polycyclic aromatic and mineral oil type hydrocarbons. Furthermore, from 22 storm events, water samples of rainfall, surface runoff, seepage and ground water were analysed with regard to the above mentioned pollutants. The study showed that the material used for the joints had a major impact on the initial as well as the final infiltration rates. Due to its poor hydraulic conductivity, limestone gravel should not be used as jointing. Furthermore, it is recommended that materials for the infiltration facilities are ensured free of any contaminants prior to construction. Polycyclic aromatic and mineral oil type hydrocarbons were, with the exception of surface runoff, below detection limits. Heavy metal concentrations of groundwater were with the exception of lead (because of high background concentrations), below the permissible limits.

Early evidence for complex social structure in Proboscidea from a late Miocene trackway site in the United Arab Emirates

PubMed Central

Bibi, Faysal; Kraatz, Brian; Craig, Nathan; Beech, Mark; Schuster, Mathieu; Hill, Andrew

2012-01-01

Many living vertebrates exhibit complex social structures, evidence for the antiquity of which is limited to rare and exceptional fossil finds. Living elephants possess a characteristic social structure that is sex-segregated and multi-tiered, centred around a matriarchal family and solitary or loosely associated groups of adult males. Although the fossil record of Proboscidea is extensive, the origin and evolution of social structure in this clade is virtually unknown. Here, we present imagery and analyses of an extensive late Miocene fossil trackway site from the United Arab Emirates. The site of Mleisa 1 preserves exceptionally long trackways of a herd of at least 13 individuals of varying size transected by that of a single large individual, indicating the presence of both herding and solitary social modes. Trackway stride lengths and resulting body mass estimates indicate that the solitary individual was also the largest and therefore most likely a male. Sexual determination for the herd is equivocal, but the body size profile and number of individuals are commensurate with those of a modern elephant family unit. The Mleisa 1 trackways provide direct evidence for the antiquity of characteristic and complex social structure in Proboscidea. PMID:22357934

Site investigation of bridges on and over the parkways in Western Kentucky.

DOT National Transportation Integrated Search

2008-06-01

Determination of the seismic risk of the bridges on and over the parkways in Western Kentucky requires evaluating the current condition of the individual elements of the bridges. Except for culverts, all bridges were visually inspected, photographed ...

RMP Guidance for Chemical Distributors - Chapter 11: Communication with the Public

EPA Pesticide Factsheets

Risk Management Plans must be made available to the public, except for any classified or confidential business information contained in RMPs or the off-site consequence analysis sections. Be prepared to communicate risk with LEPCs and SERCs.

78 FR 48817 - Hours of Service of Drivers of Commercial Motor Vehicles; Regulatory Guidance for Oilfield Exception

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-12

... hauling sand and water that is required by hydraulic fracturing (or ``fracking'') operations. Traditional... and gas exploration and the volume of traffic to and from fracking sites increased, State and local...

Biophysical properties affecting vegetative canopy reflectance and absorbed photosynthetically active radiation at the FIFE site

NASA Technical Reports Server (NTRS)

Walter-Shea, E. A.; Blad, B. L.; Hays, C. J.; Mesarch, M. A.; Deering, D. W.; Middleton, E. M.

1992-01-01

Leaves of the dominant grass species of the ISCLP FIFE site reflect and transmit radiation in a like manner to other healthy green leaves. Visible reflectance factors (RFs) and transmittance factors (TFs) were less for older leaves than younger leaves except during senescence, when RF and TF values were greater. NIR-RF values increased and TF values decreased with leaf age, with the reverse occurring as the leaf went through senescence.

The Growing Threat of Light Pollution to Ground-Based Observatories

NASA Astrophysics Data System (ADS)

Green, Richard F.; Luginbuhl, Christian; Wainscoat, Richard J.; Duriscoe, Dan

2018-01-01

With few exceptions, growing sky glow from artificial sources negatively impacts the sky background recorded at major observatories around the world. We report techniques for measuring night sky brightness and extracting the contribution of artificial sky glow at observatories and other protected sites. The increase in artificial ambient light and its changing spectrum with LED replacements is likely to be significant. A compendium of worldwide regulatory approaches to astronomical site protection gives insight on multiple effective strategies.

Site Synthesis Report of DSDP Sites 417 and 418

DTIC Science & Technology

1989-06-01

radmolarsan sands including pyrite . chert and organics (black-clay facites) VII Pale to dark red brown, pink Upper Aptian to 291.5-324.0e -32,5 418A... pyrite , pyrrhotite, chalcopyrite, and pentlaudite. Plasse (1980) and Bleil and Smith (1980b) show that titanomaghemite, the primary magnetic mineral at...Hole 418A where it occurs as a rare phenocryst. Pyrite is the most common secondary opaque mineral. Except in Hole 417A, alteration products generally

Trace element accumulation in bivalve mussels Anodonta woodiana from Taihu Lake, China.

PubMed

Liu, Hongbo; Yang, Jian; Gan, Juli

2010-11-01

Data are presented for 13 trace metals (Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Mo, Ag, Cd, and Pb) in 38 bivalve mussels Anodonta woodiana from four separate sites (Huzhou, Dapu, Sansandao, and Manshan) around the Taihu Lake of China. All elemental concentrations generally ranked in decreasing order, Mn > Fe > Zn > As ≈ Cu ≈ Cd ≈ Se > Pb > Mo ≈ Ag, except that Cr, Co, and Ni were not detected. Anodonta woodiana was able to bioaccumulate essential Mn and toxic Cd to the extremely high level of 19,240 and 53 mg/kg dry weight, respectively. Geographical differences in the concentrations of trace elements were usually significant between sampling sites except for As and Pb, and the mussels from Sanshandao site had mostly accumulated or were contaminated with essential and toxic elements. The residue level of Cd in A. woodiana from the Sanshandao and Manshan sites appeared to be even higher than those of the essential elements Cu and Se, and exceeded the corresponding maximum residue limits of China. The present study provides the most recent information on trace element bioaccumulation or contamination in Taihu Lake and, further, suggests that A. woodiana can be used as a suitable bioindicator for inland water environmental monitoring.

Water-quality assessment of the Porter County Watershed, Kankakee River basin, Porter County, Indiana

USGS Publications Warehouse

Bobo, Linda L.; Renn, Danny E.

1980-01-01

Water type in the 241-square mile Porter County watershed in Indiana, was calcium bicarbonate or mixed calcium bicarbonate and calcium sulfate. Concentrations of dissolved chemical constituents in surface water and contents of chlorinated hydrocarbons in streambed samples in the watershed were generally less than water-quality alert limits set by the U.S. Environmental Protection Agency, except in Crooked Creek. During sampling, this stream was affected by sewage, chlorinated hydrocarbons, and two chemical spills. Ranges of on-site field measurements were: specific conductance, from 102 to 1,060 micromhos per centimeter at 25 Celcius; water temperature, from 7.0 to 31.8 Celsius; pH, from 6.8 to 8.9; dissolved oxygen, from 2.5 to 14.9 milligrams per liter and from 27 to 148% saturation; and instantaneous discharge from 0 to 101 cubic feet per second. Concentrations of most dissolved-inorganic constituents (heavy metals and major ions) and dissolved solids did not vary significantly from one sampling period to the next at each site. Dissolved constituents whose concentrations varied significantly were iron, manganese, organic carbon, ammonia, nitrate plus nitrite, organic nitrogen, Kjeldahl nitrogen, and phosphorus. Concentrations of dissolved manganese, organic carbon, dissolved nitrite plus nitrate, and suspended sediment varied seasonally at most sites. Populations and identification of bacteria, phytoplankton, periphyton, and benthic invertebrates indicate a well-balanced environment at most sites, except in Crooked Creek.

Reaching the poor with health interventions: programme-incidence analysis of seven randomised trials of women's groups to reduce newborn mortality in Asia and Africa

PubMed Central

Houweling, Tanja A J; Morrison, Joanna; Alcock, Glyn; Azad, Kishwar; Das, Sushmita; Hossen, Munir; Kuddus, Abdul; Lewycka, Sonia; Looman, Caspar W; Magar, Bharat Budhathoki; Manandhar, Dharma S; Akter, Mahfuza; Dube, Albert Lazarous Nkhata; Rath, Shibanand; Saville, Naomi; Sen, Aman; Tripathy, Prasanta; Costello, Anthony

2016-01-01

Background Efforts to end preventable newborn deaths will fail if the poor are not reached with effective interventions. To understand what works to reach vulnerable groups, we describe and explain the uptake of a highly effective community-based newborn health intervention across social strata in Asia and Africa. Methods We conducted a secondary analysis of seven randomised trials of participatory women's groups to reduce newborn mortality in India, Bangladesh, Nepal and Malawi. We analysed data on 70 574 pregnancies. Socioeconomic and sociodemographic differences in group attendance were tested using logistic regression. Qualitative data were collected at each trial site (225 focus groups, 20 interviews) to understand our results. Results Socioeconomic differences in women's group attendance were small, except for occasional lower attendance by elites. Sociodemographic differences were large, with lower attendance by young primigravid women in African as well as in South Asian sites. The intervention was considered relevant and interesting to all socioeconomic groups. Local facilitators ensured inclusion of poorer women. Embarrassment and family constraints on movement outside the home restricted attendance among primigravid women. Reproductive health discussions were perceived as inappropriate for them. Conclusions Community-based women's groups can help to reach every newborn with effective interventions. Equitable intervention uptake is enhanced when facilitators actively encourage all women to attend, organise meetings at the participants’ convenience and use approaches that are easily understandable for the less educated. Focused efforts to include primigravid women are necessary, working with families and communities to decrease social taboos. PMID:26246540

LCR 5' hypersensitive site specificity for globin gene activation within the active chromatin hub.

PubMed

Peterson, Kenneth R; Fedosyuk, Halyna; Harju-Baker, Susanna

2012-12-01

The DNaseI hypersensitive sites (HSs) of the human β-globin locus control region (LCR) may function as part of an LCR holocomplex within a larger active chromatin hub (ACH). Differential activation of the globin genes during development may be controlled in part by preferential interaction of each gene with specific individual HSs during globin gene switching, a change in conformation of the LCR holocomplex, or both. To distinguish between these possibilities, human β-globin locus yeast artificial chromosome (β-YAC) lines were produced in which the ε-globin gene was replaced with a second marked β-globin gene (β(m)), coupled to an intact LCR, a 5'HS3 complete deletion (5'ΔHS3) or a 5'HS3 core deletion (5'ΔHS3c). The 5'ΔHS3c mice expressed β(m)-globin throughout development; γ-globin was co-expressed in the embryonic yolk sac, but not in the fetal liver; and wild-type β-globin was co-expressed in adult mice. Although the 5'HS3 core was not required for β(m)-globin expression, previous work showed that the 5'HS3 core is necessary for ε-globin expression during embryonic erythropoiesis. A similar phenotype was observed in 5'HS complete deletion mice, except β(m)-globin expression was higher during primitive erythropoiesis and γ-globin expression continued into fetal definitive erythropoiesis. These data support a site specificity model of LCR HS-globin gene interaction.

How well does the Post-fire Erosion Risk Management Tool (ERMiT) really work?

NASA Astrophysics Data System (ADS)

Robichaud, Peter; Elliot, William; Lewis, Sarah; Miller, Mary Ellen

2016-04-01

The decision of where, when, and how to apply the most effective postfire erosion mitigation treatments requires land managers to assess the risk of damaging runoff and erosion events occurring after a fire. The Erosion Risk Management Tool (ERMiT) was developed to assist post fire assessment teams identify high erosion risk areas and effectiveness of various mitigation treatments to reduce that risk. ERMiT is a web-based application that uses the Water Erosion Prediction Project (WEPP) technology to estimate erosion, in probabilistic terms, on burned and recovering forest, range, and chaparral lands with and without the application of mitigation treatments. User inputs are processed by ERMiT to combine rain event variability with spatial and temporal variabilities of hillslope burn severity and soil properties which are then used as WEPP inputs. Since 2007, the model has been used in making hundreds of land management decisions in the US and elsewhere. We use eight published field study sites in the Western US to compare ERMiT predictions to observed hillslope erosion rates. Most sites experience only a few rainfall events that produced runoff and sediment except for a California site with a Mediterranean climate. When hillslope erosion occurred, significant correlations occurred between the observed hillslope erosion and those predicted by ERMiT. Significant correlation occurred for most mitigation treatments as well as the five recovery years. These model validation results suggest reasonable estimates of probabilistic post-fire hillslope sediment delivery when compared to observation.

Alternative Work Schedules Increase Employee Satisfaction.

ERIC Educational Resources Information Center

Turney, John R.; Cohen, Stanley L.

1983-01-01

Facets of alternative work schedules (AWS) are discussed: importance of employee control, possible negative consequences, AWS handbook, time monitoring systems, and treatment of exceptions. AWS' effect on productivity and motivation is examined. (SK)

Expressive Arts for Exceptional Children in the Mainstream: Working Papers.

ERIC Educational Resources Information Center

Kingsley, Ronald F., Ed.; Michaels, Eunice R., Ed.

The document contains nine presentations and five miniworkshop papers from a teacher institute on expressive arts for exceptional children in the mainstream. The following titles and authors are represented: "The Educator and Mainstreaming--A State of Mind and a Set of Skills" (G. Bailey); "The Arts in the Mainstream" (G. Barlow); "The Emergence…

Nothing Exceptional: Against Agamben

ERIC Educational Resources Information Center

Colatrella, Steven

2011-01-01

Giorgio Agamben's work has become widely influential as a guide to explaining the extra-constitutional powers assumed by governments under the rubric of the War on Terror. His formulations, such as Homo Sacer and State of Exception, have been extended to apply to a wide variety of experiences of repression of liberties or social control, including…

Distribution and variability of precipitation chemistry in the conterminous United States, January through December 1983

USGS Publications Warehouse

Rinella, J.F.; Miller, T.L.

1988-01-01

Analysis of atmospheric precipitation samples, collected during the 1983 calendar year from 109 National Trends Network sites in the United States, are presented in this report. The sites were grouped into six geographical regions based on the chemical composition of the samples. Precipitation chemistry in these regions was influenced by proximity to (1) oceans, (2) major industrial and fossil-fuel consuming areas, and (3) major agricultural and livestock areas. Frequency distributions of ionic composition, determined on 10 chemical constituents and on precipitation quantities for each site, showed wide variations in chemical concentrations and precipitation quantities from site to site. Of the 109 sites, 55 had data coverage for the year sufficient to characterize precipitation quality patterns on a nationwide basis. Except for ammonium and calcium, both of which showed largest concentrations in the agricultural midwest and plains states, the largest concentrations and loads generally were in areas that include the heavily industrialized population center of the eastern United States. Except for hydrogen, all chemical ions are inversely related to the quantity of precipitation depth. Precipitation quantities generally account for less than 30% of chemical variation in precipitation samples. However, precipitation quantities account for 30 to 65% of the variations of calcium concentrations in precipitation. In regions where precipitation has a large ionic proportion of hydrogen-ion equivalents, much of the hydrogen-ion concentration could be balanced by sulfate equivalents and partly balanced by nitrite-plus-nitrate equivalents. In the regions where hydrogen-ion equivalents in precipitation were smaller, ammonion-and calcium-ion equivalents were necessary, along with the hydrogen-ion equivalents, to balance the sulfate plus nitrite-plus-nitrate equivalent. (USGS)

Use of tolerance values to diagnose water-quality stressors to aquatic biota in New England streams

USGS Publications Warehouse

Meador, M.R.; Carlisle, D.M.; Coles, J.F.

2008-01-01

Identification of stressors related to biological impairment is critical to biological assessments. We applied nationally derived tolerance indicator values for four water-quality variables to fish and benthic macroinvertebrate assemblages at 29 sites along an urban gradient in New England. Tolerance indicator values (TIVs), as biologically based predictors of water-quality variables, were determined for dissolved oxygen, nitrite plus nitrate (nitrate), total phosphorus, and water temperature for each site based on observed biological assemblages (TIVO), and for expected assemblages (TIVE). The quotient method, based on a ratio of the TIVs for observed and expected assemblages (tolerance units), was used to diagnose potential water-quality stressors. In addition, the ratio of measured water-quality values to water-quality criteria (water-quality units) was calculated for each water-quality variable to assess measured water-quality stressors. Results from a RIVPACS predictive model for benthic macroinvertebrates and Bray-Curtis dissimilarity for fish were used to classify sites into categories of good or impaired ecological condition. Significant differences were detected between good and impaired sites for all biological tolerance units (fish and benthic macroinvertebrate assemblages averaged) except for nitrate (P = 0.480), and for all water-quality units except for nitrate (P = 0.183). Diagnosis of water-quality stressors at selected sites was, in general, consistent with State-reported causes of impairment. Tolerance units for benthic macroinvertebrate and fish assemblages were significantly correlated for water temperature (P = 0.001, r = 0.63), dissolved oxygen (P = 0.001, r = 0.61), and total phosphorus (P = 0.001, r = 0.61), but not for nitrate (P = 0.059, r = -0.35). Differences between the two assemblages in site-specific diagnosis of water-quality stressors may be the result of differences in nitrate tolerance.

The structure of western warbler assemblages: Analysis of foraging behavior and habitat selection in Oregon

USGS Publications Warehouse

Morrison, Michael L.

1981-01-01

This study examines the foraging behavior and habitat selection of a MacGillivray's (Oporornis tolmiei)-Orange-crowned (Vermivora celata)-Wilson's (Wilsonia pusilla) warbler assemblage that occurred on early-growth clearcuts in western Oregon during breeding. Sites were divided into two groups based on the presence or absence of deciduous trees. Density estimates for each species were nearly identical between site classes except for Wilson's, whose density declined on nondeciduous tree sites. Analysis of vegetation parameters within the territories of the species identified deciduous tree cover as the variable of primary importance in the separation of warblers on each site, so that the assemblage could be arranged on a continuum of increasing deciduous tree cover. MacGillivray's and Wilson's extensively used shrub cover and deciduous tree cover, respectively; Orange-crowns were associated with both vegetation types. When the deciduous tree cover was reduced, Orange-crowns concentrated foraging activities in shrub cover and maintained nondisturbance densities. Indices of foraging-height diversity showed a marked decrease after the removal of deciduous trees. All species except MacGillivray's foraged lower in the vegatative substrate on the nondeciduous tree sites; MacGillivray's concentrated foraging activities in the low shrub cover on both sites. Indices of foraging overlap revealed a general pattern of decreased segregation by habitat after removal of deciduous trees. I suggest that the basic patterns of foraging behavior and habitat selection evidenced today in western North America were initially developed by ancestral warblers before their invasion of the west. Species successfully colonizing western habitats were probably preadapted to the conditions they encountered, with new habitats occupied without obvious evolutionary modifications.

30 CFR 75.153 - Electrical work; qualified person.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electrical work; qualified person. 75.153....153 Electrical work; qualified person. (a) Except as provided in paragraph (f) of this section, an individual is a qualified person within the meaning of §§ 75.511 and 75.512 to perform electrical work (other...

30 CFR 75.153 - Electrical work; qualified person.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electrical work; qualified person. 75.153....153 Electrical work; qualified person. (a) Except as provided in paragraph (f) of this section, an individual is a qualified person within the meaning of §§ 75.511 and 75.512 to perform electrical work (other...

30 CFR 75.153 - Electrical work; qualified person.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electrical work; qualified person. 75.153....153 Electrical work; qualified person. (a) Except as provided in paragraph (f) of this section, an individual is a qualified person within the meaning of §§ 75.511 and 75.512 to perform electrical work (other...

30 CFR 77.704 - Work on high-voltage lines; deenergizing and grounding.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Work on high-voltage lines; deenergizing and... OF UNDERGROUND COAL MINES Grounding § 77.704 Work on high-voltage lines; deenergizing and grounding. High-voltage lines shall be deenergized and grounded before work is performed on them, except that...

30 CFR 75.153 - Electrical work; qualified person.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electrical work; qualified person. 75.153....153 Electrical work; qualified person. (a) Except as provided in paragraph (f) of this section, an individual is a qualified person within the meaning of §§ 75.511 and 75.512 to perform electrical work (other...

30 CFR 75.153 - Electrical work; qualified person.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electrical work; qualified person. 75.153....153 Electrical work; qualified person. (a) Except as provided in paragraph (f) of this section, an individual is a qualified person within the meaning of §§ 75.511 and 75.512 to perform electrical work (other...

"Embedded" Youth Work: Ethical Questions for Youth Work Professionals

ERIC Educational Resources Information Center

Sercombe, Howard

2007-01-01

Most professions have wrestled with the problem of dual relationships, and the profession of youth work is no exception. Howard Sercombe holds that in order to understand how dual relationships can be avoided within youth work, it is necessary to be clear about what is involved in professional relationships. Sercombe also outlines policies that…

7 CFR 654.14 - Duration of sponsor(s)' responsibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... performed by force account, division of work, or performance of work methods, the sponsor(s)' O&M responsibilities begin on the date the work or portion thereof is completed as determined by NRCS, except for completed work located on Federal lands which are subject to special-use permits. The O&M agreement shall...

Working with the Exceptional Student.

ERIC Educational Resources Information Center

Hunter, Madeline

1989-01-01

To work productively with all students, teachers need to examine four major determinants of human learning: neural equipment; learning history; learning strategies, such as imaging, paraphrasing, summarizing, and generating examples; and quality of teaching. (JDD)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, N.W.; Wickenden, D.A.; Roberts, E.P.L.

Arvia{sup R}, working with Magnox Ltd, has developed the technology of adsorption coupled with electrochemical regeneration for the degradation of orphan radioactive oil wastes. The process results in the complete destruction of the organic phase where the radioactivity is transferred to liquid and solid secondary wastes that can then be processed using existing authorised on-site waste-treatment facilities.. Following on from successful laboratory and pilot scale trials, a full scale, site based demonstrator unit was commissioned at the Magnox Trawsfynydd decommissioning site to destroy 10 l of LLW and ILW radioactive oils. Over 99% of the emulsified oil was removed andmore » destroyed with the majority of activity (80 - 90%) being transferred to the aqueous phase. Secondary wastes were disposed of via existing routes with the majority being disposed of via the sites active effluent treatment plant. The regeneration energy required to destroy a litre of oil was 42.5 kWh/l oil. This on-site treatment approach eliminates the risks and cost associated with transporting the active waste oils off site for incineration or other treatment. The Arvia{sup R} process of adsorption coupled with electrochemical regeneration has successfully demonstrated the removal and destruction of LLW and ILW radioactive oils on a nuclear site. Over 99.9% of the emulsified oil was removed, with the majority of the radioactive species transferred to the aqueous, supernate, phase (typically 80 - 90 %). The exception to this is Cs-137 which appears to be more evenly distributed, with 43% associated with the liquid phase and 33 % with the Nyex, the remainder associated with the electrode bed. The situation with Plutonium may be similar, but this requires confirmation, hence further work is underway to understand the full nature of the electrode bed radioactive burden and its distribution within the body of the electrodes. - Tritium gaseous discharges were negligible; hence no off-gas treatment before direct discharge to atmosphere is necessary. All secondary wastes were suitable for disposal using existing disposal routes, with the majority of the activity being successfully discharged as active water via the site active drains. - Oil destruction was achieved at a rate of 28.2 ml/hr using a regeneration energy of 42.5 kWh/l oil. The treatment of different active and non-active oils was achieved using the same operating parameters, providing strong evidence that the process is robust and will treat a wide range of oils, organic wastes and additives. - Currently the design of a plant capable of processing 1000 ml/hr is being established in discussion with Magnox Ltd. The plant will run automatically with little operator attention and so process between 5-8 m{sup 3} of ILW oil per annum. (authors)« less

42 CFR 411.362 - Additional requirements concerning physician ownership and investment in hospitals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... an exception is granted by the Secretary pursuant to section 1877(i)(3) of the Social Security Act... public Web site for the hospital and in any public advertising that the hospital is owned or invested in...

10 CFR 100.4 - Communications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Communications. 100.4 Section 100.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REACTOR SITE CRITERIA § 100.4 Communications. Except where otherwise... Reactor Regulation or Director, Office of New Reactors, as appropriate, U.S. Nuclear Regulatory Commission...

10 CFR 100.4 - Communications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Communications. 100.4 Section 100.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REACTOR SITE CRITERIA § 100.4 Communications. Except where otherwise... Reactor Regulation or Director, Office of New Reactors, as appropriate, U.S. Nuclear Regulatory Commission...

Use of Additives in Bioremediation of Contaminated Groundwater and Soil

EPA Science Inventory

This chapter reviews application of additives used in bioremediation of chlorinated solvents and fuels for groundwater and soil remediation. Soluble carbon substrates are applicable to most site conditions except aquifers with very high or very low groundwater flow. Slow-release ...

10 CFR 100.4 - Communications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Communications. 100.4 Section 100.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REACTOR SITE CRITERIA § 100.4 Communications. Except where otherwise specified, all communications and reports concerning the regulations in this part and applications filed...

10 CFR 100.4 - Communications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Reactor Regulation or Director, Office of New Reactors, as appropriate, U.S. Nuclear Regulatory Commission... 10 Energy 2 2012-01-01 2012-01-01 false Communications. 100.4 Section 100.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REACTOR SITE CRITERIA § 100.4 Communications. Except where otherwise...

Calculating wave-generated bottom orbital velocities from surface-wave parameters

USGS Publications Warehouse

Wiberg, P.L.; Sherwood, C.R.

2008-01-01

Near-bed wave orbital velocities and shear stresses are important parameters in many sediment-transport and hydrodynamic models of the coastal ocean, estuaries, and lakes. Simple methods for estimating bottom orbital velocities from surface-wave statistics such as significant wave height and peak period often are inaccurate except in very shallow water. This paper briefly reviews approaches for estimating wave-generated bottom orbital velocities from near-bed velocity data, surface-wave spectra, and surface-wave parameters; MATLAB code for each approach is provided. Aspects of this problem have been discussed elsewhere. We add to this work by providing a method for using a general form of the parametric surface-wave spectrum to estimate bottom orbital velocity from significant wave height and peak period, investigating effects of spectral shape on bottom orbital velocity, comparing methods for calculating bottom orbital velocity against values determined from near-bed velocity measurements at two sites on the US east and west coasts, and considering the optimal representation of bottom orbital velocity for calculations of near-bed processes. Bottom orbital velocities calculated using near-bed velocity data, measured wave spectra, and parametric spectra for a site on the northern California shelf and one in the mid-Atlantic Bight compare quite well and are relatively insensitive to spectral shape except when bimodal waves are present with maximum energy at the higher-frequency peak. These conditions, which are most likely to occur at times when bottom orbital velocities are small, can be identified with our method as cases where the measured wave statistics are inconsistent with Donelan's modified form of the Joint North Sea Wave Project (JONSWAP) spectrum. We define the 'effective' forcing for wave-driven, near-bed processes as the product of the magnitude of forcing times its probability of occurrence, and conclude that different bottom orbital velocity statistics may be appropriate for different problems. ?? 2008 Elsevier Ltd.

Prevalence, characteristics, and impacts of work-related musculoskeletal disorders: a survey among physical therapists in the State of Kuwait

PubMed Central

2010-01-01

Background Physical therapists working in the State of Kuwait are at risk of work-related musculoskeletal disorders (WMSDs). However, prevalence rates and risk factors are not well documented. The objective of this study was to determine the prevalence, characteristics, and impacts of WMSDs among physical therapists in the State of Kuwait. Methods A self-administered questionnaire was distributed to 350 physical therapists. The questionnaire gathered demographic data as well as information on occurrence of musculoskeletal complaints in the previous 12 months. Descriptive statistics, frequency, and Chi-square analyses were used. Results The response rate to the questionnaire was 63% (222/350). Of the 212 responders included in the study, the one-year prevalence of WMSDs was 47.6%, with lower back complaints as the most common (32%). This was followed by neck (21%), upper back (19%), shoulder (13%), hand/wrist (11%), knee (11%), ankle/foot (6%), elbow (4%), and hip/thigh (3%) complaints. The frequency of WMSDs was not gender related (except lower back, neck, and shoulder complaints) nor was it related to age (except lower back complaints), working venues (except hand/wrist), working hours, area of specialty, or exercise. WMSDs' impact on work was minor. Conclusions WMSDs among physical therapists in Kuwait were common, with lower back and neck affected most. Lower back and neck WMSDs were related to the participant's demographics. Hand/wrist WMSDs were related to work settings. Further research is needed to investigate the effect of risk factors as physical load, psychosocial load, and general health status on prevalence musculoskeletal disorders. PMID:20540724

Satellite Estimation of Daily Land Surface Water Vapor Pressure Deficit from AMSR- E

NASA Astrophysics Data System (ADS)

Jones, L. A.; Kimball, J. S.; McDonald, K. C.; Chan, S. K.; Njoku, E. G.; Oechel, W. C.

2007-12-01

Vapor pressure deficit (VPD) is a key variable for monitoring land surface water and energy exchanges, and estimating plant water stress. Multi-frequency day/night brightness temperatures from the Advanced Microwave Scanning Radiometer on EOS Aqua (AMSR-E) were used to estimate daily minimum and average near surface (2 m) air temperatures across a North American boreal-Arctic transect. A simple method for determining daily mean VPD (Pa) from AMSR-E air temperature retrievals was developed and validated against observations across a regional network of eight study sites ranging from boreal grassland and forest to arctic tundra. The method assumes that the dew point and minimum daily air temperatures tend to equilibrate in areas with low night time temperatures and relatively moist conditions. This assumption was tested by comparing the VPD algorithm results derived from site daily temperature observations against results derived from AMSR-E retrieved temperatures alone. An error analysis was conducted to determine the amount of error introduced in VPD estimates given known levels of error in satellite retrieved temperatures. Results indicate that the assumption generally holds for the high latitude study sites except for arid locations in mid-summer. VPD estimates using the method with AMSR-E retrieved temperatures compare favorably with site observations. The method can be applied to land surface temperature retrievals from any sensor with day and night surface or near-surface thermal measurements and shows potential for inferring near-surface wetness conditions where dense vegetation may hinder surface soil moisture retrievals from low-frequency microwave sensors. This work was carried out at The University of Montana, at San Diego State University, and at the Jet Propulsion Laboratory, California Institute of Technology, under contract to the National Aeronautics and Space Administration.

Paleoceanographic history of the Lower Bengal Fan during the last glacial cycle - IODP Expedition 354

NASA Astrophysics Data System (ADS)

Dekens, P. S.; Weber, M. E.; Lantzsch, H.; Das, S. K.; Williams, T.; Adhikari, R. R.; Jia, G.; Fox, L. R.; Ge, J.; Manoj, M. C.; Savian, J. F.; Reilly, B. T.; Selkin, P. A.; Meynadier, L.; Spiess, V.; France-Lanord, C.; Sharma, B.

2015-12-01

IODP Expedition 354 drilled a ~320 km long transect of seven sites on the Lower Bengal Fan at 8o N in the Northern Indian Ocean. The sediments cores recovered record a complex relationship between turbiditic and hemipelagic environments. This variability offers a unique opportunity to link our understanding of tectonic and terrestrial processes with climate and oceanography. With the exception the westernmost Site U1454, all sites show a several meter thick, hemipelagic top layer, usually representing Late Quaternary sediment. We present physical, geochemical and stable isotopic properties of this interval to establish a time frame and assess the paleoceanographic development of the region during the last glacial cycle. We sampled Site U1452C-1H continuously for the uppermost 480 cm of hemipelagic sediment in 2-cm increments. Preliminary results indicate the Toba Ash 1 (0.74 ka) is a distinct time marker in all physical properties. Furthermore, wet-bulk density as well as color reflectance b* (the red-green component) and L* (the lightness) show a dominant precession cyclicity. Hence, we are able to provide an insolation-tuned chronology for the last 200 ka (MIS1 - 7) as a preliminary age model. These records agree well with d18O records retrieved from Chinese caves. We will present a preliminary paleoceanographic proxy data to reconstruct sea-surface temperature (SST), sea-surface salinity (SSS), ice volume, marine biological productivity, nutrient supply, and deep-water circulation. These oceanographic and climate conditions are linked to changes in monsoonal strength and terrestrial input using sedimentary proxies to reconstruct chemical weathering and sediment sources and transport time. This work addresses one of the primary cruise objectives - linking monsoon variability, regional and global climate, and Bay of Bengal sediment deposition.

Stable nitrogen and carbon isotope (δ 15N and δ 13C) variability in shallow tropical Pacific soft coral and black coral taxa and implications for paleoceanographic reconstructions

NASA Astrophysics Data System (ADS)

Williams, Branwen; Grottoli, Andréa G.

2010-09-01

Soft corals and black corals are useful proxy tools for paleoceanographic reconstructions. However, most work has focused on deep-water taxa and few studies have used these corals as proxy organisms in shallow water (<200 m). To facilitate the use of stable nitrogen and carbon isotope (δ 15N and δ 13C) records from shallow-water soft coral and black coral taxa for paleoceanographic reconstructions, quantification of the inherent variability in skeletal isotope values between sites, across depth, and among taxa is needed. Here, skeletal δ 15N and δ 13C values were measured in multiple colonies from eleven genera of soft corals and two genera of black corals from across a depth transect (5-105 m) at two sites in Palau located in the tropical western Pacific Ocean. Overall, no difference in skeletal δ 15N and δ 13C values between sites was present. Skeletal δ 15N values significantly increased and δ 13C values decreased with depth. This is consistent with changes in isotope values of suspended particulate organic matter (POM) across the photic zone, suggesting that the primary food source to these corals is suspended POM and that the stable isotopic composition of POM controls the skeletal isotopic composition of these corals. Thus, to compare the isotope records of corals collected across a depth range in the photic zone, first order depth corrections of -0.013‰ m -1 and +0.023‰ m -1 are recommended for δ 15N and δ 13C, respectively. Average depth-corrected δ 15N values were similar between black corals and soft corals, indicating that corals in these orders feed at a similar trophic level. In contrast, average depth-corrected δ 13C values of black corals were significantly lower than that of soft corals, potentially resulting from metabolic processes associated with differing skeletal compositions among the orders (i.e., gorgonin vs. chitin based). Thus, a correction of +1.0‰ is recommended for black corals when comparing their δ 13C-based proxy records to soft corals. After correcting for both the depth and order effects, variability in δ 15N values among corals within each genera was low (standard deviation (SD) of the mean <±0.5‰), with the exception of Acanthorgorgia. The calculated SD of <±0.5‰ provides a first order guideline for the amount of variability that could be expected in a δ 15N record, and suggests that these corals may be useful for δ 15N-based paleoceanographic reconstructions. Variability in δ 13C values among corals within genera was also low (standard deviation of the mean <±0.5‰) with the exception of Rhipidipathes and Villogorgia. Similar to δ 15N, records from the genera studied here with the exception of Rhipidipathes and Villogorgia may be useful for δ 13C-based paleoceanographic reconstructions. Overall, using the recommendations developed here, stable isotope records from multiple sites, depths and taxa of these corals can be more rigorously compared.

Measuring the level of agreement in hematologic and biochemical values between blood sampling sites in leatherback sea turtles (Dermochelys coriacea).

PubMed

Stewart, Kimberly; Mitchell, Mark A; Norton, Terry; Krecek, Rosina C

2012-12-01

Conservation programs to protect endangered sea turtles are being instituted worldwide. A common practice in these programs is to collect blood to evaluate the health of the turtles. Several different venipuncture sites are used to collect blood from sea turtles for hematologic and biochemistry tests, depending on the species. To date, it is unknown what affect venipuncture site may have on sample results. The purpose of this study was to measure the level of agreement between hematologic and biochemistry values collected from the dorsal cervical sinus and the interdigital vein of leatherback (Dermochelys coriacea) sea turtles. Paired heparinized blood samples were obtained from the dorsal cervical sinus and the interdigital vein of 12 adult female nesting leatherback sea turtles on Keys Beach, St. Kitts, West Indies. Even though the sample population was small, the data for each chemistry were normally distributed, except for creatine kinase (CK). There was no significant difference when comparing biochemistry or hematologic values by venipuncture site, except for CK (P = 0.02). The level of agreement between sampling sites was considered good for albumin, calcium, globulin, glucose, packed cell volume, phosphorus, potassium, sodium, total protein, total solids, uric acid, white blood cell count, and all of the individual white cell types, while the level of agreement for aspartate aminotransferase and CK were considered poor. This information, coupled with the fact that the interdigital vein affords a less-invasive procedure, demonstrates that the interdigital vein is an appropriate location to use when establishing a hematologic and biochemical profile for leatherback sea turtles.

Reliability of abstracting performance measures: results of the cardiac rehabilitation referral and reliability (CR3) project.

PubMed

Thomas, Randal J; Chiu, Jensen S; Goff, David C; King, Marjorie; Lahr, Brian; Lichtman, Steven W; Lui, Karen; Pack, Quinn R; Shahriary, Melanie

2014-01-01

Assessment of the reliability of performance measure (PM) abstraction is an important step in PM validation. Reliability has not been previously assessed for abstracting PMs for the referral of patients to cardiac rehabilitation (CR) and secondary prevention (SP) programs. To help validate these PMs, we carried out a multicenter assessment of their reliability. Hospitals and clinical practices from around the United States were invited to participate in the Cardiac Rehabilitation Referral Reliability (CR3) Project. Twenty-nine hospitals and 23 outpatient centers expressed interest in participating. Seven hospitals and 6 outpatient centers met participation criteria and submitted completed data. Site coordinators identified 35 patients whose charts were reviewed by 2 site abstractors twice, 1 week apart. Percent agreement and the Cohen κ statistic were used to describe intra- and interabstractor reliability for patient eligibility for CR/SP, patient exceptions for CR/SP referral, and documented referral to CR/SP. Results were obtained from within-site data, as well as from pooled data of all inpatient and all outpatient sites. We found that intra-abstractor reliability reflected excellent repeatability (≥ 90% agreement; κ ≥ 0.75) for ratings of CR/SP eligibility, exceptions, and referral, both from pooled and site-specific analyses of inpatient and outpatient data. Similarly, the interabstractor agreement from pooled analysis ranged from good to excellent for the 3 items, although with slightly lower measures of reliability. Abstraction of PMs for CR/SP referral has high reliability, supporting the use of these PMs in quality improvement initiatives aimed at increasing CR/SP delivery to patients with cardiovascular disease.

Mesophotic coral ecosystems under anthropogenic stress: a case study at Ponce, Puerto Rico

NASA Astrophysics Data System (ADS)

Appeldoorn, Richard; Ballantine, David; Bejarano, Ivonne; Carlo, Milton; Nemeth, Michael; Otero, Ernesto; Pagan, Francisco; Ruiz, Hector; Schizas, Nikolaos; Sherman, Clark; Weil, Ernesto

2016-03-01

Mesophotic coral ecosystems (MCEs) were compared between La Parguera and Ponce, off the south coast of Puerto Rico. In contrast to La Parguera, Ponce has a narrow insular shelf and hosts several river outlets, a commercial port, a regional sewage treatment plant with associated deep water outfall, and three deep dredge disposal sites. Off Ponce, MCEs receive higher (16×) rates of sedimentation than off La Parguera, a less impacted site. The most impacted sites were located offshore of Cayo Ratones and are in or down-current and in close proximity to one of the dredge disposal sites. There, MCEs are characterized by a steep, irregular, rocky slope with a cover of fine-grained, dark brown sediment, which increases with depth. At shallower depths, scattered rocky outcroppings are colonized by sponges, black corals and algae. The sediment cover contains two to three times the terrigenous content and a significantly higher percentage of the fine-grained fraction than off La Parguera. Thirteen remotely operated vehicle (ROV) dives east and west of Ponce showed that the deepest depth at which corals were observed increased with distance from Cayo Ratones and did not approach depths observed off La Parguera except at the eastern-most (up-current) site, Caja de Muertos, which was also significantly further offshore. Benthic communities off Caja de Muertos were comparable to those at La Parguera, while off Cayo Ratones, there were no mesophotic corals and sparse development of other benthic macrobiota except sponges. Management authorities should include MCEs when assessing potential impacts from anthropogenic activities and take the necessary steps to reduce local threats.

Prevalence of Sexually Transmitted Diseases and Risk Behaviors from the NIMH Collaborative HIV/STD Prevention Trial.

PubMed

Celentano, David D; Mayer, Kenneth H; Pequegnat, Willo; Abdala, Nadia; Green, Annette M; Handsfield, H Hunter; Hartwell, Tyler D

2010-01-01

This cross-sectional study describes the baseline prevalence and correlates of common bacterial and viral sexually transmitted diseases (STDs) and risk behaviors among individuals at high risk for HIV recruited in five low- and middle-income countries. Correlations of risk behaviors and demographic factors with prevalent STDs and the association of STDs with HIV prevalence are examined. Between 2,212 and 5,543 participants were recruited in each of five countries (China, India, Peru, Russia, and Zimbabwe). Standard protocols were used to collect behavioral risk information and biological samples for STD testing. Risk factors for HIV/STD prevalence were evaluated using logistic regression models. STD prevalence was significantly higher for women than men in all countries, and the most prevalent STD was Herpes simplex virus-type 2 (HSV-2). HIV prevalence was generally low (below 5%) except in Zimbabwe (30% among women, 11.7% among men). Prevalence of bacterial STDs was generally low (below 5% for gonorrhea and under 7% for syphilis in all sites), with the exception of syphilis among female sex workers in India. Behavioral and demographic risks for STDs varied widely across the five study sites. Common risks for STDs included female gender, increasing number of recent sex partners, and in some sites, older age, particularly for chronic STDs (i.e., HSV-2 and HIV). Prevalence of HIV was not associated with STDs except in Zimbabwe, which showed a modest correlation between HIV and HSV-2 prevalence (Pearson coefficient = .55). These findings underscore the heterogeneity of global STD and HIV epidemics and suggest that local, focused interventions are needed to achieve significant declines in these infections.

Preliminary Micropaleontological Investigation of a Preserved, Late Pleistocene Cypress Forest on the Northern Gulf of Mexico Inner Shelf

NASA Astrophysics Data System (ADS)

Truong, J. T.; DeLong, K. L.; Bentley, S. J.; Xu, K.; Harley, G. L.; Reese, A.; Gonzalez, S.; Obelcz, J.; Caporaso, A.

2017-12-01

Exposed at the bottom of a trough 13 km offshore Orange Beach, AL on the Gulf of Mexico (GOM) shelf in 18 m water depth are exceptionally preserved in situ bald cypress (Taxodium distichum) stumps. Preserved seeds (T. distichum, Cephalanthus occidentalis, Hibiscus lasiocarpos, Liquidambar styraciflua) discovered in core catcher samples illustrate the exceptional preservation of the site. Woody debris samples have come back radiocarbon dead with an exception to samples located in the upper peat layer with 14C ages from 37,350-41,830 years BP. Optically stimulated luminescence and 14C dates, in combination with GOM eustatic sea level curves, suggest the forest was located 30 m above the paleoshoreline. How the forest remained preserved during subaerial exposure of the continental shelf through the Last Glacial Maximum lowstand until ensuing Holocene sea level transgression remains unknown. The R/V Coastal Profiler collected 7 vibracores from the study site in 2015 and an additional 11 in 2016. A single core (DF1) contains facies identified as the Holocene Mississippi-Alabama-Florida sand sheet, a transitional facies of interbedded sand and mud, and a basal floodplain facies in which the stumps reside. This study seeks to identify the location of the Pleistocene-Holocene unconformity and to assist in stratigraphy of the area. Foraminiferal assemblages found within the transitional facies are of a shallow marine environment that suggests Holocene in age. It is hypothesized that a pulse of sea level rise during Marine Isotope Stages 3-4 caused subsequent rapid aggradation of the paleovalley system allowing for preservation through >30 kyrs of subaerial exposure. One of the ultimate goals of this study is to serve as a guide for identification of other possible sites along the gulf coast.

Differences in incidence rates and early detection of cancer among non-Hispanic and Hispanic Whites in the United States.

PubMed

Merrill, Ray M; Harris, Jessica D; Merrill, Joseph G

2013-01-01

Our study compared cancer incidence rates and stage distribution between non-Hispanic Whites and Hispanic Whites in the United States between 1992 and 2009. A retrospective cohort study was conducted for the years 1992 through 2009. Data represent 13 registries in the Surveillance, Epidemiology, and End Results Program, which reflect 14% of the total US population. The incidence rates for most cancer sites were significantly higher in non-Hispanic Whites than in Hispanic Whites. Exceptions included cancers of the stomach and liver and, for females only, kidney and renal pelvis and cervix uteri. Overall, cancer incidence in non-Hispanic Whites was 40% greater in males and 34% greater in females as compared with Hispanic Whites. Cancer sites with higher incidence rates among non-Hispanic Whites than Hispanic Whites in 2009 compared with 1992 were melanoma, thyroid cancer, oral cavity and pharynx cancer, lymphoma, urinary bladder cancer, and all cancers combined for males and melanoma, thyroid cancer, cervical cancer, and lung and bronchus cancer for females. However, difference in rates narrowed between the ethnicities for colon and rectal cancer and corpus and uterus cancer. Non-Hispanic Whites tended to have a higher percentage of early staged cancer, with little evidence that disparity between the ethnic groups was narrowing in terms of early detection. However, two exceptions involved liver cancer and thyroid cancer in females. The disparity appeared to widen for lung cancer in males. Cancer incidence rates are generally lower in Hispanic Whites than non-Hispanic Whites. The difference in rates between groups has widened over the study period for many cancer sites, with a few exceptions. Poorer screening practices among Hispanic Whites have tended to persist.

Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity.

PubMed

Weir, Marion E; Mann, Jacqueline E; Corwin, Thomas; Fulton, Zachary W; Hao, Jennifer M; Maniscalco, Jeanine F; Kenney, Marie C; Roman Roque, Kristal M; Chapdelaine, Elizabeth F; Stelzl, Ulrich; Deming, Paula B; Ballif, Bryan A; Hinkle, Karen L

2016-04-01

Src family tyrosine kinases (SFKs) are critical players in normal and aberrant biological processes. While phosphorylation importantly regulates SFKs at two known tyrosines, large-scale phosphoproteomics have revealed four additional tyrosines commonly phosphorylated in SFKs. We found these novel tyrosines to be autophosphorylation sites. Mimicking phosphorylation at the C-terminal site to the activation loop decreased Fyn activity. Phosphomimetics and direct phosphorylation at the three SH2 domain sites increased Fyn activity while reducing phosphotyrosine-dependent interactions. While 68% of human SH2 domains exhibit conservation of at least one of these tyrosines, few have been found phosphorylated except when found in cis to a kinase domain. © 2016 Federation of European Biochemical Societies.

Using Heavy Metal Content and Lipid Peroxidation Indicators in the Tissues of the Mussel Crenomytilus grayanus for Pollution Assessment After Marine Environmental Remediation.

PubMed

Belcheva, Nina; Istomina, Alexandra; Dovzhenko, Nadezhda; Lishavskaya, Tatiana; Chelomin, Victor

2015-10-01

We examined the effects of environmental remediation on the heavy metal concentration and lipid peroxidation activity in the digestive gland and gills of the marine mussel Crenomytilus grayanus. Changes in heavy metal concentrations and lipid peroxidation biomarkers in the tissues of mussels collected at a contaminated site were compared with those obtained from a reference site. Prior to remediation the concentration of Pb, Cu, Cd, Fe and Zn and the levels of malondialdehyde, conjugated dienes and lipofuscin in mussels collected from the contaminated site were significantly increased compared with those obtained from the reference site. Three years after remediation, these parameters did not significantly exceed the reference site parameters, except Pb, whose concentration, though markedly decreased, yet was much higher than in tissues of mussels from the reference site.

Assessment of occupational exposure to polycyclic aromatic hydrocarbons via involuntary ingestion of soil from contaminated soils in Lagos, Nigeria.

PubMed

Adetunde, Oluwatoyin T; Mills, Graham A; Olayinka, Kehinde O; Alo, Babajide I

2014-01-01

Soils from 12 sites in Lagos area, Nigeria impacted by anthropogenic activities were extracted by ultrasonication and analysed for the concentration of 16 priority polycyclic aromatic hydrocarbons (PAHs) by gas chromatograph-mass spectrometer (GC-MS). The concentration of the sum of PAHs ranged from 0.2 to 254 μg/g at these sites. The sum benzo[a]pyrene-equivalent dose (BaPeq) at the sites ranged from 0.0 (K, forest soil) to 16.7 μg/g (C, the lubricating oil depot soil). Mean daily intake (MDI) for the composite soils samples when compared that of food revealed that some of the individual PAH in samples from sites A (Dump site), C (Depot and loading point for used for black oil), F (Dump site), G(petroleum depot), H (Roadside) and L (Car park) exceeded the recommended the recommended MDI threshold for food, indicating some risk associated with activities on these sites based on this ingestion estimate exceeded value. 8.2 × 10(-6), 7.1 × 10(-7), 1.2 × 10(-4), 4.9 × 10(-7), 7.3 × 10(-7), 1.4 × 10(-5), 7.9 × 10(-5), 4.6 × 10(-6), 3.4 × 10(-7), 2.4 × 10(-7), 2.2 × 10(-7) and 1.1 × 10(-4) estimated theoretical cancer risk (ER) for an adult with a body weight of 70 kg working on sites were composite soil samples A, B, C, D, E, F, G, H, I, J, K and L respectively were sampled. The ER from occupational exposure to surface soil based on oral ingestion were all higher than the target risk of 1 × 10(-6) for normal exposure but were all within the 1 × 10(-4) for extreme exposure for most of the sites except for site C and L. The differences in concentration and risk were related to the different activities (e.g., handling of petroleum products, open burning, bush burning) undertaken at these locations. However, it should be noted here that the resultant risk could be overestimated, since these calculations were based on an exhaustive extraction technique which may be different from uptake by the human guts (bioavailability study).

Nearshore Community Studies of Neah Bay, Washington

DTIC Science & Technology

1988-06-01

between 5 and 20 species at most sites (Miller et al. 1980; Long (1983). Only Beckett Point (Discovery Bay) had fish species richness appmaching the 47...while most of the MESA sites during spring and summer 1976-1979 had standing crops below 5 g m-2 ; only Twin Rivers (-9- -18 g m-2) and Beckett Point...tow-net standing crops, in contrast, were typically below 0.25 g m-3, except for catches at Dungeness Spit and Beckett Point which ranged as high as

A Methodology for Determining Land Value and Associated Benefits Created from Dredged Material Containment.

DTIC Science & Technology

1978-06-01

accessibility. 228. The diagram below represents the basic relationship among the physical criteria: n^^^o MLl»3 Geographic Location Setting ^ r-; 11 T>,r...value is the difference be- tween the raw site value and the development value. The diagram below illustrates the basic relationship among the...except for the effect of demand on market price and the length of time that a site would remain on the market. The diagram below illustrates the

Asymmetric Iridium Catalyzed C-C Coupling of Chiral Diols via Site-Selective Redox-Triggered Carbonyl Addition

PubMed Central

Shin, Inji; Krische, Michael J.

2015-01-01

Cyclometalated π-allyliridium C,O-benzoate complexes modified by axially chiral chelating phosphine ligands display a pronounced kinetic preference for primary alcohol dehydrogenation, enabling highly site-selective redox-triggered carbonyl additions of chiral primary-secondary 1,3-diols with exceptional levels of catalyst-directed diastereoselectivity. Unlike conventional methods for carbonyl allylation, the present redox-triggered alcohol C-H functionalizations bypass the use of protecting groups, premetalated reagents, and discrete alcohol-to-aldehyde redox reactions. PMID:26187028

29 CFR 1915.96 - Work in or on lifeboats.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., shipbuilding, and shipbreaking except that paragraph (b) of this section applies to ship repairing and shipbuilding only. (a) Before employees are permitted to work in or on a lifeboat, either stowed or in a...

29 CFR 4.115 - Exemptions and exceptions, generally.

Code of Federal Regulations, 2013 CFR

2013-07-01

... repair, including painting and decorating of public buildings or public works; (2) Any work required to..., railway line, or oil or gas pipeline where published tariff rates are in effect; (4) Any contract for the...

29 CFR 4.115 - Exemptions and exceptions, generally.

Code of Federal Regulations, 2014 CFR

2014-07-01

... repair, including painting and decorating of public buildings or public works; (2) Any work required to..., railway line, or oil or gas pipeline where published tariff rates are in effect; (4) Any contract for the...

29 CFR 4.115 - Exemptions and exceptions, generally.

Code of Federal Regulations, 2012 CFR

2012-07-01

... repair, including painting and decorating of public buildings or public works; (2) Any work required to..., railway line, or oil or gas pipeline where published tariff rates are in effect; (4) Any contract for the...

Composition and microstructure of Roman metallic artefacts of Southwestern Iberian Peninsula

NASA Astrophysics Data System (ADS)

Valério, P.; Voráčová, E.; Silva, R. J. C.; Araújo, M. F.; Soares, A. M. M.; Arruda, A. M.; Pereira, C.

2015-10-01

The Roman invasion introduces new alloys and metallurgical practices in Iberian Peninsula. The southwestern end of this region has many evidences of connections with the Roman World, but there are no studies about the manufacture and use of copper-based artefacts during this period. Therefore, a set of about 20 ornaments, tools and small attachments recovered at the Roman sites of Monte Molião and Cidade das Rosas was studied by an analytical approach combining micro-EDXRF, optical microscopy, SEM-EDS and Vickers microhardness testing. The artefact composition shows a good correlation with function, namely pure copper for nails and rivets, low-tin bronze (2-6 wt% Sn) for basic tools, high-tin bronze (14 wt% Sn) for fibulae and high-lead bronze (19 wt% Pb) for a decorated jug handle. The manufacture also depends on function because most artefacts were subjected to thermomechanical processing, except the ornaments that would not benefit from post-casting work. Brass and gunmetal were only present in the site with a later chronology. A metallurgy visibly ruled by economical, aesthetical and technological concerns reinforces the evidences about the total integration of Southwestern Iberian Peninsula in the Roman World, but further studies will be essential to determine the evolution of copper-based alloys in Lusitania under Roman influence.

Effects of septic tank effluent on ground-water quality, Dade County, Florida: an interim report

USGS Publications Warehouse

Pitt, William A.

1974-01-01

Except at one site, no fecal coliforms were found below the 10-foot depth. Total coliforms exceeded a count of one colony per ml at the 60- foot depth at two sites. At one site a fecal streptococci count of 53 colonies per ml was found at the 60-foot depth and at another a count of seven colonies was found at the 40-foot depth. The three types of bacteria occur in higher concentration in the northern areas of the county than in the south. Bacteria concentrations were also higher where the septic tanks were more concentrated. 

78 FR 940 - Proposed Administrative Cost Recovery Settlement Under Section 122(h) of the Comprehensive...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... Liability Act, as Amended, Former W&J Lanyon Zinc Works Superfund Site, Pittsburg, Crawford County, KS... compromise of past response costs concerning the Former W&J Lanyon Zinc Works Superfund Site (the ``Site... 66219, (913) 551-7567. Requests should reference the Former W&J Lanyon Zinc Works Superfund Site, EPA...

Twice-Exceptional Learners: The Journey toward a Shared Vision

ERIC Educational Resources Information Center

Baldwin, Lois; Baum, Susan; Pereles, Daphne; Hughes, Claire

2015-01-01

For more than 50 years, the unique needs of twice-exceptional (2e) learners have challenged educators. Because of this challenge, much work has been done in different areas across the country in creating appropriate learning environments for serving this population. However, no unified way has been developed to bring together the best research and…

Mind the Gap: Appropriate Evolutionary Perspectives toward the Integration of the Sciences and Humanities

ERIC Educational Resources Information Center

Heywood, Leslie L.; Garcia, Justin R.; Wilson, David Sloan

2010-01-01

Although Darwinism has gained a foothold in the social sciences, in the humanities, with a few exceptions, it is still largely rejected--not, as some would claim, because humanists are all radical poststructuralists who deny that material reality exists, but rather because, with notable exceptions, Darwinists who work within the humanities have…

75 FR 13416 - Federal Acquisition Regulation; FAR Case 2008-006, Enhanced Competition for Task- and Delivery...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

.... ``Unusual and Compelling Urgency.'' In the event of a FAR subpart 6.3 exception for a single contract award over $100 million including an unusual and compelling urgency exception, the commenter expresses... work. In those situations, it does not make sense in terms of costs and efficiency to require the...

Exceptional Scholarship and Democratic Agendas: Interviews with John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni

ERIC Educational Resources Information Center

Mullen, Carol A.

2006-01-01

This portraiture study of four exceptional scholars in education--John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni--provides insight into their scholarly work and life habits, direction and aspirations, assessment and analysis of major trends in the profession, and advice for aspiring leaders and academics. Telephone interviews with…

Exceptional Scholarship and Democratic Agendas: Interviews with John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni

ERIC Educational Resources Information Center

Mullen, Carol A.

2009-01-01

This portraiture study of four exceptional scholars in education--John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni--provides insight into their scholarly work and life habits, direction and aspirations, assessment and analysis of major trends in the profession, and advice for aspiring leaders and academics. Telephone interviews with…

Working with Adults with Exceptional Needs: A Guide for the Trainer.

ERIC Educational Resources Information Center

Carlisle, Lynn, Comp.; Connelly, Trudy, Comp.

This guide, written for persons who conduct training sessions, workshops or other meetings attended by adults with exceptional needs, begins with a brief outline of the characteristics of adult learners. A list of 10 true-false statements is then presented to assess knowledge of disabling conditions and some common myths surrounding society's…

Making Language Work Better for Handicapped People and Everyone Else. A Guide for Writers, Editors, and Publishers.

ERIC Educational Resources Information Center

Mullins, June

Intended for producers of educational materials, the document offers guidelines to assure that print and nonprint educational materials reflect a positive, fair, and balanced representation of persons with exceptionalities. Nine guidelines are discussed: (1) 10% of the contents should include or represent children or adults with an exceptionality;…

48 CFR 52.236-3 - Site Investigation and Conditions Affecting the Work.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Conditions Affecting the Work. 52.236-3 Section 52.236-3 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.236-3 Site Investigation and Conditions Affecting the Work. As prescribed in 36.503, insert the following clause: Site Investigation and Conditions Affecting the Work (APR 1984) (a) The...

Framing charitable donations as exceptional expenses increases giving.

PubMed

Sussman, Abigail B; Sharma, Eesha; Alter, Adam L

2015-06-01

Many articles have examined the psychological drivers of charitable giving, but little is known about how people mentally budget for charitable gifts. The present research aims to address this gap by investigating how perceptions of donations as exceptional (uncommon and infrequent) rather than ordinary (common and frequent) expenses might affect budgeting for and giving to charity. We provide the first demonstration that exceptional framing of an identical item can directly influence mental budgeting processes, and yield societal benefits. In 5 lab and field experiments, exceptional framing increased charitable behavior, and diminished the extent to which people considered the effect of the donation on their budgets. The current work extends our understanding of mental accounting and budgeting for charitable gifts, and demonstrates practical techniques that enable fundraisers to enhance the perceived exceptionality of donations. (c) 2015 APA, all rights reserved).

10 CFR 963.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the sealing of shafts and ramps, except those openings that may be designed for ventilation or... repository, as defined by this section, at the Yucca Mountain site. Design means a description of the... includes the engineered barrier system. Design bases means that information that identifies the specific...

10 CFR 963.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the sealing of shafts and ramps, except those openings that may be designed for ventilation or... repository, as defined by this section, at the Yucca Mountain site. Design means a description of the... includes the engineered barrier system. Design bases means that information that identifies the specific...

18 CFR 50.9 - Notice of application.

Code of Federal Regulations, 2010 CFR

2010-04-01

.... 50.9 Section 50.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT APPLICATIONS FOR PERMITS TO SITE INTERSTATE ELECTRIC TRANSMISSION FACILITIES § 50.9 Notice of application. (a) Notice of each application filed, except...

48 CFR 52.249-1 - Termination for Convenience of the Government (Fixed-Price) (Short Form).

Code of Federal Regulations, 2014 CFR

2014-10-01

..., may terminate this contract, in whole or in part, when it is in the Government's interest. If this..., except for property that the Contractor (a) disposed of by bona fide sale or (b) removed from the site...

15 CFR 265.39 - Weapons and explosives.

Code of Federal Regulations, 2010 CFR

2010-01-01

... INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE REGULATIONS GOVERNING TRAFFIC AND CONDUCT REGULATIONS GOVERNING TRAFFIC AND CONDUCT ON THE GROUNDS OF THE NATIONAL INSTITUTE OF STANDARDS & TECHNOLOGY... explosives. Except in connection with the conduct of official business on the site, no person other than...

38 CFR 36.4221 - Delegation of authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Delegation of authority. 36.4221 Section 36.4221 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Site Preparation General Provisions § 36.4221 Delegation of authority. (a) Except as hereinafter...

10 CFR 963.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the sealing of shafts and ramps, except those openings that may be designed for ventilation or... repository, as defined by this section, at the Yucca Mountain site. Design means a description of the... includes the engineered barrier system. Design bases means that information that identifies the specific...

10 CFR 963.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the sealing of shafts and ramps, except those openings that may be designed for ventilation or... repository, as defined by this section, at the Yucca Mountain site. Design means a description of the... includes the engineered barrier system. Design bases means that information that identifies the specific...

10 CFR 963.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the sealing of shafts and ramps, except those openings that may be designed for ventilation or... repository, as defined by this section, at the Yucca Mountain site. Design means a description of the... includes the engineered barrier system. Design bases means that information that identifies the specific...

5 CFR 550.112 - Computation of overtime work.

Code of Federal Regulations, 2010 CFR

2010-01-01

... meal time. (1) Bona fide sleep and meal periods may not be considered hours of work, except as provided... a call to duty, the time spent on duty is hours of work. (2) Sleep and meal periods during regularly....C. 5545(c)(1), the amount of bona fide sleep and meal time excluded from hours of work may not...

5 CFR 550.112 - Computation of overtime work.

Code of Federal Regulations, 2011 CFR

2011-01-01

... meal time. (1) Bona fide sleep and meal periods may not be considered hours of work, except as provided... a call to duty, the time spent on duty is hours of work. (2) Sleep and meal periods during regularly....C. 5545(c)(1), the amount of bona fide sleep and meal time excluded from hours of work may not...

The comparative effectiveness of clinic, work-site, phone, and Web-based tobacco treatment programs.

PubMed

An, Lawrence C; Betzner, Anne; Schillo, Barbara; Luxenberg, Michael G; Christenson, Matthew; Wendling, Ann; Saul, Jessie E; Kavanaugh, Annette

2010-10-01

Tobacco treatment programs may be offered in clinical settings, at work-sites, via telephone helplines, or over the Internet. Little comparative data exist regarding the real-world effectiveness of these programs. This paper compares the reach, effectiveness, and costs of these different modes of cessation assistance. This is an observational study of cohorts of participants in Minnesota's QUITPLAN programs in 2004. Cessation assistance was provided in person at 9 treatment centers, using group counseling at 68 work-sites, via a telephone helpline, or via the Internet. The main outcomes of the study are enrollment by current smokers, self-reported 30-day abstinence, and cost per quit. Reach was calculated statewide for the helpline and Web site, regionally for the treatment centers, and for the employee population for work-site programs. Enrollment was greatest for the Web site (n = 4,698), followed by the helpline (n = 2,351), treatment centers (n = 616), and work-sites (n = 479). The Web site attracted younger smokers. Smokers at treatment centers had higher levels of nicotine dependence. The helpline reached more socially disadvantaged smokers. Responder 30-day abstinence rates were higher for the helpline (29.3%), treatment centers (25.8%), and work-sites (19.6%) compared with the online program (12.5%). These differences persisted after controlling for baseline differences in participant characteristics and use of pharmacological therapy. The cost per quit was lowest for the Web site program ($291 per quit, 95% CI = $229-$372). Treatment center, work-site, helpline, and Web site programs differ in their reach, effectiveness, and estimated cost per quit. Each program plays a part in assisting populations of tobacco users in quitting.

29 CFR 778.415 - The statutory provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS OVERTIME COMPENSATION Exceptions From the Regular Rate Principles Computing Overtime Pay on the Rate Applicable to the Type of Work Performed in... performance of the work, the amount paid to the employee for the number of hours worked by him in such...

40 CFR 35.2116 - Collection system.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Collection system. 35.2116 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2116 Collection system. Except as provided in § 35.2032(c), if the project involves collection system work, such work: (a) Shall...

40 CFR 35.2116 - Collection system.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Collection system. 35.2116 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2116 Collection system. Except as provided in § 35.2032(c), if the project involves collection system work, such work: (a) Shall...

A Call for Conducting Multivariate Mixed Analyses

ERIC Educational Resources Information Center

Onwuegbuzie, Anthony J.

2016-01-01

Several authors have written methodological works that provide an introductory- and/or intermediate-level guide to conducting mixed analyses. Although these works have been useful for beginning and emergent mixed researchers, with very few exceptions, works are lacking that describe and illustrate advanced-level mixed analysis approaches. Thus,…

Effects of land use on water quality and transport of selected constituents in streams in Mecklenburg County, North Carolina, 1994–98

USGS Publications Warehouse

Ferrell, Gloria M.

2001-01-01

Transport rates for total solids, total nitrogen, total phosphorus, biochemical oxygen demand, chromium, copper, lead, nickel, and zinc during 1994–98 were computed for six stormwater-monitoring sites in Mecklenburg County, North Carolina. These six stormwater-monitoring sites were operated by the Mecklenburg County Department of Environmental Protection, in cooperation with the City of Charlotte, and are located near the mouths of major streams. Constituent transport at the six study sites generally was dominated by nonpoint sources, except for nitrogen and phosphorus at two sites located downstream from the outfalls of major municipal wastewater-treatment plants.To relate land use to constituent transport, regression equations to predict constituent yield were developed by using water-quality data from a previous study of nine stormwater-monitoring sites on small streams in Mecklenburg County. The drainage basins of these nine stormwater sites have relatively homogeneous land-use characteristics compared to the six study sites. Mean annual construction activity, based on building permit files, was estimated for all stormwater-monitoring sites and included as an explanatory variable in the regression equations. These regression equations were used to predict constituent yield for the six study sites. Predicted yields generally were in agreement with computed yields. In addition, yields were predicted by using regression equations derived from a national urban water-quality database. Yields predicted from the regional regression equations generally were about an order of magnitude lower than computed yields.Regression analysis indicated that construction activity was a major contributor to transport of the constituents evaluated in this study except for total nitrogen and biochemical oxygen demand. Transport of total nitrogen and biochemical oxygen demand was dominated by point-source contributions. The two study basins that had the largest amounts of construction activity also had the highest total solids yields (1,300 and 1,500 tons per square mile per year). The highest total phosphorus yields (3.2 and 1.7 tons per square mile per year) attributable to nonpoint sources also occurred in these basins. Concentrations of chromium, copper, lead, nickel, and zinc were positively correlated with total solids concentrations at most of the study sites (Pearson product-moment correlation >0.50). The site having the highest median concentrations of chromium, copper, and nickel also was the site having the highest computed yield for total solids.

A chromatographic estimate of the degree of heterogeneity of RPLC packing materials. 1. Non-endcapped polymeric C30-bonded stationary phase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gritti, Fabrice; Guiochon, Georges A

2006-01-01

A new chromatographic method estimating the degree of heterogeneity of RPLC packing materials is based on the results of systematic measurements of the adsorption data in a wide concentration range for selected probe compounds. These data are acquired by frontal analysis (FA), modeled, and used for the calculation of the adsorption energy distribution (AED). Four compounds were used, two neutral compounds of different molecular sizes (caffeine and phenol) and two ionizable compounds of opposite charges, 2-naphthalene sulfonate, an anion, and propranololium, a cation. This work was done on a C{sub 30}-bonded silica stationary phase (Prontosil-C{sub 30}), using the same aqueousmore » mobile phase (30% methanol, v/v) for all compounds, except that sodium chloride (25 mM) was added to elute the ionizable compounds. All four adsorption isotherms have Langmuirian behavior. The AEDs are tri-modal for phenol, quadri-modal for caffeine. The total saturation capacity of the stationary phase is four-fold lower for caffeine than for phenol, due in part to its larger molecular size. The equilibrium constants on the low-energy sites of types 1 and 2 are eight-fold larger. These two types of sites characterize the heterogeneity of the bonded layer itself. The density of the high-energy sites of types 3 and 4 is higher for caffeine, suggesting that caffeine molecules can be accommodated in some hydrophobic cages into which smaller molecules like phenol cannot. These high-energy types of sites characterize the heterogeneity of the whole stationary phase (silica support included). The ionizable compounds have larger molecules than the neutral ones and, accordingly, a lower relative density of sites of type 2 to sites of type 1. A tri-modal and a quadri-modal energy distributions were observed for the 2-naphthalene sulfonate anion and the propranololium cation, respectively. The fourth types of sites measured and its unusually high equilibrium constant are most probably due to ion-exchange interactions between the non-endcapped ionized silanols and the propranololium ion. No such strong interactions are observed with the anionic compound.« less

Rates of Eolian Rock Abrasion in the Ice-Free Valleys, Antarctica

NASA Astrophysics Data System (ADS)

Hallet, B.; Malin, M. C.; Sletten, R. S.

2016-12-01

Eolian abrasion is a principal surface process in dry regions of Earth and Mars and there is evidence for wind processes active on Venus and Titan. Rock abrasion also has practical significance in diverse fields ranging from preservation of cultural material (artifacts, monuments) to damage of solar panels and windshields in arid regions. Despite its scientific and practical importance, and there have ben only few studies that define rates of rock abrasion quantitatively under natural conditions. Herein we report abrasion rates that have been exceptionally well characterized through a unique long-term (30+-year) field experiment in the ice-free McMurdo Dry Valleys, Antarctica. In 1983 and 1984, over 5000 rock targets of several lithologies (25.4 mm-diameter and 5 mm-thick disks of dolerite, basalt, tuff and sandstone) were installed at five heights (7,14, 21, 35, and 70 cm) facing the 4 cardinal directions at 10 locations (one additional site contains fewer targets). Sequential collections of rock targets exposed to abrasion enable definition of mass loss after 1, 5, 10, 30 and 31 years of exposure; the latter were retrieved during the 2014-2015 season. The abrasion rates generally show striking consistency for each lithology at any site; the multiple targets permit definition of intrinsic differences in mass loss. The rates vary considerably from site to site owing to differences in availability of transportable sediment, wind regime, and surface roughness, and at each site, owing to target orientation relative to the dominant winds and, secondarily, to height above the ground. For the hardest targets, basalt and dolerite, mass loss in 30+ years ranged from essentially zero at some sites to 1/3 of the deployed mass (2.59 g; equivalent to a rock thickness >1.8 mm) where abrasion was most active (Site 7, Central Wright Valley). The tuff targets showed the greatest mass loss, and in many cases were entirely abraded away by the end of the experiment.Current work is focused on understanding the spatial and directional variation in measured mass losses based on a wealth of information.

29 CFR 785.12 - Work performed away from the premises or job site.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Work performed away from the premises or job site. 785.12 Section 785.12 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... premises or job site. The rule is also applicable to work performed away from the premises or the job site...

10 CFR 2.104 - Notice of hearing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... work authorization, construction permit, early site permit, or combined license for a facility of the... work authorization, construction permit, early site permit, or combined license for a facility of the... hearing concerning an application for a limited work authorization, construction permit, early site permit...

Local Media Influence on Opting-Out from an Exception from Informed Consent Trial

PubMed Central

Nelson, Maria J; DeIorio, Nicole M; MD, Terri Schmidt; Griffiths, Denise; Daya, Mohamud; Haywood, Liana; Zive, Dana; Newgard, Craig D

2010-01-01

Objectives News media are used for community education and notification in exception from informed consent clinical trials, yet their effectiveness as an added safeguard in such research remains unknown. We assessed the number of callers requesting opt-out bracelets following each local media report and described the errors and content within each media report. Methods We undertook a descriptive analysis of local media trial coverage (newspaper, television, radio, and weblog) and opt-out requests over a 41-month period at a single site participating in an exception from informed consent out-of-hospital trial. Two non-trial investigators independently assessed forty-one content-based media variables (including background, trial information, graphics, errors, publication information, assessment) using a standardized, semi-qualitative data collection tool. Major errors were considered serious misrepresentation of the trial purpose or protocol, whereas minor errors included misinformation unlikely to mislead the lay reader about the trial. We plotted the temporal relationship between opt-out bracelet requests and media reports. Descriptive information about the news sources and the trial coverage are presented. Results We collected 39 trial-related media reports (33 newspaper, 1 television, 1 radio, and 4 blogs). There were thirteen errors in 9 (23%) publications, 7 of which were major and 6 minor. Of 384 requests for 710 bracelets, 310 requests (80%) occurred within 4 days after trial media coverage. Graphical timeline representation of the data suggested a close association between media reports about the trial and requests for opt-out bracelets. Conclusions Based on results from a single site, local media coverage for an exception from informed consent clinical trial had a substantial portion of errors and appeared closely associated with opt-out requests. PMID:19682770

Work-site wellness programmes in Sweden: a cross-sectional study of physical activity, self-efficacy, and health.

PubMed

Gånedahl, H; Zsaludek Viklund, P; Carlén, K; Kylberg, E; Ekberg, J

2015-05-01

In Sweden, a work-site wellness programme implies reimbursing some of the expenses for health-promoting activities. Although work-site wellness programmes are readily available in Sweden, a large number of employees elect not to participate. The aim of this study was to investigate the association of physical activity, self-reported general health assessment and self-efficacy with participation in a work-site wellness programme. A cross-sectional study design was used. An online questionnaire was distributed to employees of a manufacturing company with 2500 employees in southwest Sweden. Those who took advantage of the work-site wellness programme assessed their general health as better and had higher assessment of physical activity. The study showed that being enlisted also implies a higher level of physical activity and general health; however, the effect sizes of these correlations were small. Self-efficacy, i.e. perceived behavioural control, was not associated with participation in the work-site wellness programme. However, self-efficacy was correlated with both general health assessment and physical activity. A regression analysis to determine explanatory contributions to the general health assessment score showed no significant contribution from participation in a work-site wellness programme, but was instead explained by perceived behavioural control and physical activity. Given the small effect size of the difference in physical activity between participators and non-participators in the work-site wellness programme, it is probable that only a small proportion of participators changed their health-promoting activities as a result of the work-site wellness programme. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Drug resistance conferred by mutations outside the active site through alterations in the dynamic and structural ensemble of HIV-1 protease.

PubMed

Ragland, Debra A; Nalivaika, Ellen A; Nalam, Madhavi N L; Prachanronarong, Kristina L; Cao, Hong; Bandaranayake, Rajintha M; Cai, Yufeng; Kurt-Yilmaz, Nese; Schiffer, Celia A

2014-08-27

HIV-1 protease inhibitors are part of the highly active antiretroviral therapy effectively used in the treatment of HIV infection and AIDS. Darunavir (DRV) is the most potent of these inhibitors, soliciting drug resistance only when a complex combination of mutations occur both inside and outside the protease active site. With few exceptions, the role of mutations outside the active site in conferring resistance remains largely elusive. Through a series of DRV-protease complex crystal structures, inhibition assays, and molecular dynamics simulations, we find that single and double site mutations outside the active site often associated with DRV resistance alter the structure and dynamic ensemble of HIV-1 protease active site. These alterations correlate with the observed inhibitor binding affinities for the mutants, and suggest a network hypothesis on how the effect of distal mutations are propagated to pivotal residues at the active site and may contribute to conferring drug resistance.

37 CFR 201.39 - Notice to Libraries and Archives of Normal Commercial Exploitation or Availability at Reasonable...

Code of Federal Regulations, 2014 CFR

2014-07-01

... English (except for an original title, which may be in another language), typed or printed legibly in dark... information on Deposit Accounts, see Circular 5 on the U.S. Copyright Office's Web site, or request a copy at...

Logs and data from trenches across the Hayward Fault at Tyson's Lagoon (Tule Pond), Fremont, Alameda County, California

USGS Publications Warehouse

Linenkaemper, James J.; Dawson, Timothy E.; Personius, Stephen F.; Seitz, Gordon G.; Reidy, Liam M.; Schwartz, David P.

2002-01-01

INTRODUCTION The purpose of this publication is to make available detailed trench logs (sheets 1, 2), radiocarbon dates (table 1) and pollen data (fig. 1) obtained as a result of an intensive subsurface investigation of the Hayward Fault at Tyson's Lagoon (Tule Pond) from August to November 2000 (figs. 1, 2 on sheet 1). The Hayward Fault is recognized to be among the most hazardous in the United States (Working Group on California Earthquake Probabilities, 1999). This document makes available geologic evidence for historical and prehistoric surfacerupturing earthquakes that were recorded at the site. Prehistoric earthquakes deduced from geologic evidence are called paleoearthquakes. Establishing a chronology of paleoearthquakes is of immediate use in resolving the level of hazard posed by the Hayward Fault for producing large earthquakes in the future. Preliminary findings of this investigation have been presented in Lienkaemper and others (2001). A formal report on our conclusions based on these data is in preparation. The investigation at Tyson's Lagoon is ongoing, so these products should not be considered final. Lienkaemper, Dawson, and Personius interpreted the geology and logged the trenches. Seitz and Reidy performed analyses on radiocarbon and pollen samples, respectively. Schwartz led the critical-review field team. Previous trenching work was done at Tyson's Lagoon (figs. 2, 3 on sheet 1). Lienkaemper (1992) references the location of most of those trenches. The earlier trenching was generally for the evaluation of local faultrupture hazard, except for the study of Williams (1993), which was a paleoearthquake investigation. An unpublished study by J.N. Alt in 1998 (shown on our site map as trenches 98A and 98B, fig. 3, on sheet 1), also sought evidence of paleoearthquakes. Alt's study and one by Woodward-Clyde and Associates (1970; trenches 70A to 70G, fig. 3) were located south of Walnut Avenue in one of the few areas that still remain undisturbed and were, thus, useful in planning our work in 2000.

No evidence for depletion of carbohydrate pools in Scots pine (Pinus sylvestris L.) under drought stress

PubMed Central

Gruber, A.; Pirkebner, D.; Florian, C.; Oberhuber, W.

2012-01-01

The physiological mechanisms leading to Scots pine (Pinus sylvestris L.) decline in the dry inner Alpine valleys are still unknown. Testing the carbon starvation hypothesis, we analysed the seasonal course of mobile carbohydrate pools (NSC) of Scots pine growing at a xeric and a dry-mesic site within an inner Alpine dry valley (750 m a.s.l., Tyrol, Austria) during the year 2009, which was characterized by exceptional soil dryness. Although, soil moisture content dropped to c. 10% at both sites during the growing season, NSC concentrations were rising in all tissues (branch, stem, root) till end of July, except in needles where maxima were reached around bud break. NSC concentrations were not significantly different in the analysed tissues at the xeric and the dry-mesic site. At the dry-mesic site NSC concentrations in the above ground tree biomass were significantly higher during the period of radial growth. An accumulation of NSC in roots at the end of July indicates a change in carbon allocation after an early cessation in above ground growth, possibly due to elevated below ground carbon demand. In conclusion our results revealed that extensive soil dryness during the growing season did not lead to carbon depletion. However, even though C-reserves were not exhausted, a sequestration of carbohydrate pools during drought periods might lead to deficits in carbon supply that weaken tree vigour and drive tree mortality. PMID:21974742

No evidence for depletion of carbohydrate pools in Scots pine (Pinus sylvestris L.) under drought stress.

PubMed

Gruber, A; Pirkebner, D; Florian, C; Oberhuber, W

2012-01-01

The physiological mechanisms leading to Scots pine (Pinus sylvestris L.) decline in the dry inner alpine valleys are still unknown. Testing the carbon starvation hypothesis, we analysed the seasonal course of mobile carbohydrate pools (NSC) of Scots pine growing at a xeric and a dry-mesic site within an inner alpine dry valley (750 m a.s.l., Tyrol, Austria) during 2009, which was characterised by exceptional soil dryness. Although, soil moisture content dropped to ca. 10% at both sites during the growing season, NSC concentrations rose in all tissues (branch, stem, root) until the end of July, except in needles, where maxima were reached around bud break. NSC concentrations were not significantly different in the analysed tissues at the xeric and the dry-mesic site. At the dry-mesic site, NSC concentrations in the aboveground tree biomass were significantly higher during the period of radial growth. An accumulation of NSC in roots at the end of July indicates a change in carbon allocation after an early cessation in aboveground growth, possibly due to elevated belowground carbon demand. In conclusion, our results revealed that extensive soil dryness during the growing season did not lead to carbon depletion. However, even though carbon reserves were not exhausted, sequestration of carbohydrate pools during drought periods might lead to deficits in carbon supply that weaken tree vigour and drive tree mortality. © 2011 German Botanical Society and The Royal Botanical Society of the Netherlands.

Early Education and the Exceptional Child. Proceedings of the Annual Montana Symposium (4th, Billings, Montana, April 27-29, 1983).

ERIC Educational Resources Information Center

Mason, Christine Y., Ed.

The proceedings of a 1983 symposium on early education and the exceptional child features 18 presentations of overall issues, cost effectiveness, special projects, social interaction, and curriculum and instructional issues. Works with the following titles and authors are included: "Education: A Look to the Future" (J. Tawney); "Movement from…

Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering.

PubMed

Karimova, Madina; Splith, Victoria; Karpinski, Janet; Pisabarro, M Teresa; Buchholz, Frank

2016-07-22

Precise genome engineering is instrumental for biomedical research and holds great promise for future therapeutic applications. Site-specific recombinases (SSRs) are valuable tools for genome engineering due to their exceptional ability to mediate precise excision, integration and inversion of genomic DNA in living systems. The ever-increasing complexity of genome manipulations and the desire to understand the DNA-binding specificity of these enzymes are driving efforts to identify novel SSR systems with unique properties. Here, we describe two novel tyrosine site-specific recombination systems designated Nigri/nox and Panto/pox. Nigri originates from Vibrio nigripulchritudo (plasmid VIBNI_pA) and recombines its target site nox with high efficiency and high target-site selectivity, without recombining target sites of the well established SSRs Cre, Dre, Vika and VCre. Panto, derived from Pantoea sp. aB, is less specific and in addition to its native target site, pox also recombines the target site for Dre recombinase, called rox. This relaxed specificity allowed the identification of residues that are involved in target site selectivity, thereby advancing our understanding of how SSRs recognize their respective DNA targets.

Morphological, biochemical, and histopathological indices and contaminant burdens of cotton rats (Sigmodon hispidus) at three hazardous waste sites near Houston, Texas, USA

USGS Publications Warehouse

Rattner, B.A.; Flickinger, Edward L.; Hoffman, D.J.

1993-01-01

Male cotton rats (Sigmodon hispidus) were studied at three industrial waste sites near Houston, Texas, to determine whether various morphological, biochemical, and histopathological indices provided evidence of contaminant exposure and toxic insult. Only modest changes were detected in cotton rats residing at waste sites compared with reference sites. No single parameter was consistently altered, except hepatic cytochrome P-450 concentration which was lower ( [Formula: see text] ) at two waste sites, and tended to be lower ( [Formula: see text] ) at a third waste site. Elevated petroleum hydrocarbon concentrations were detected in rats at one waste site, but contaminant burdens of rats from the other sites were unremarkable. Unlike rats captured in summer, those trapped in winter exhibited hepatocellular hypertrophy and up to a 65% increase in liver: body weight ratio, cytochrome P-450 concentration, and activities of aniline hydroxylase, aryl hydrocarbon hydroxylase, and glutathione S-transferase. Although genotoxicity has been previously documented in cotton rats residing at two of the waste sites, biomarkers in the present study provided little evidence of exposure and damage

Holocene records of geomagnetic field behavior from a north-south transect along the western Antarctic Peninsula

NASA Astrophysics Data System (ADS)

Brachfeld, S. A.; Shah, D. P.; St-Onge, M.; St-Onge, G.

2013-12-01

Geochronology is inherently difficult when working with Antarctic margin sediments. Radiocarbon dating and oxygen isotope stratigraphy are challenging or impossible in sites with poor preservation of biogenic calcite. Radiocarbon dating of the acid insoluble organic matter (AIOM) is further complicated by organically lean sediment and the presence of reworked organic carbon or detrital carbon from sedimentary rocks. These complications limit the ability to interpret a paleoclimate record. Geomagnetic paleointensity dating is a proven 'tuning' technique that has been successfully applied in several studies around the Antarctic margin. However, the reference curves to which these sites were tuned were constructed primarily from Northern Hemisphere data. Here we present paleomagnetic secular variation (PSV) and relative paleointensity (RPI) data from three Antarctic Peninsula sites that possess independent chronologies and which have moderate to ultra-high sedimentation rates (40 - 700 cm/ka). Maxwell Bay, located in the volcanic South Shetland Islands, is an ultra-high-resolution site with strongly magnetic sediments from which the Shallow Drilling (SHALDRIL) program recovered a 108-m record spanning the last 14 ka. Outer Barilari Bay and Hugo Island Trough, which lie to the South along the western Antarctic Peninsula, are moderate resolution sites with a high proportion of biogenic silica. Maxwell Bay and Bariliari Bay are unique in that they possess homogenous sediment and uniform magnetic mineral assemblages, while also preserving biogenic calcite, a rare combination on the Antarctic margin. All three sites preserve strong, stable remanent magnetizations with an easily isolated characteristic component and MAD values generally < 2°, with the exception of turbidites, intervals with abundant dropstones, and biosiliceous ooze intervals. Inclination values fluctuate between the present-day value at the cores sites (-58°) and the geomagnetic axial dipole inclination (-77°) values for each site, with a temporal wavelength of approximately 1000 years. The Holocene intensity of the geomagnetic field in this region was highest during the last 3000 years, broadly similar to patterns observed in the Northern Hemisphere. The records will be stacked in order to generate a regional reference curve for the Antarctic Peninsula. Moreover, these sites have the potential to fill a spatial gap in the distribution of paleomagnetic records that are used in geomagnetic field models.

Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors

PubMed Central

Cordón-Barris, Lluís; Pascual-Guiral, Sònia; Yang, Shaobin; Giménez-Llort, Lydia; Lope-Piedrafita, Silvia; Niemeyer, Carlota; Claro, Enrique; Lizcano, Jose M.

2016-01-01

The phosphoinositide (PI) 3-kinase/Akt signaling pathway plays essential roles during neuronal development. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) coordinates the PI 3-kinase signals by activating 23 kinases of the AGC family, including Akt. Phosphorylation of a conserved docking site in the substrate is a requisite for PDK1 to recognize, phosphorylate, and activate most of these kinases, with the exception of Akt. We exploited this differential mechanism of regulation by generating neuron-specific conditional knock-in mice expressing a mutant form of PDK1, L155E, in which the substrate-docking site binding motif, termed the PIF pocket, was disrupted. As a consequence, activation of all the PDK1 substrates tested except Akt was abolished. The mice exhibited microcephaly, altered cortical layering, and reduced circuitry, leading to cognitive deficits and exacerbated disruptive behavior combined with diminished motivation. The abnormal patterning of the adult brain arises from the reduced ability of the embryonic neurons to polarize and extend their axons, highlighting the essential roles that the PDK1 signaling beyond Akt plays in mediating the neuronal responses that regulate brain development. PMID:27644329

Coexistence of ferromagnetism and spin glass freezing in the site-disordered kagome ferrite SrSn2Fe4O11

NASA Astrophysics Data System (ADS)

Shlyk, Larysa; Strobel, S.; Farmer, B.; De Long, L. E.; Niewa, R.

2018-05-01

Single-crystal x-ray diffraction refinements indicate SrSn2Fe4O11 crystallizes in the hexagonal R-type ferrite structure with non-centrosymmetric space group P63mc and lattice parameters a = 5.9541(2) Å, c = 13.5761(5) Å, Z = 2 (R(F) = 0.034). Octahedrally coordinated sites are randomly occupied by Sn and Fe; whereas tetrahedrally coordinated sites are exclusively occupied by Fe, whose displacement from ideal trigonal-bipyramidal coordination causes the loss of inversion symmetry. DC magnetization data indicate SrSn2Fe4O11 single crystals undergo ferro- or ferri-magnetic order below a transition temperature TC = 630 K with very low coercive fields Hc ⊥ = 0.27 Oe and Hc// = 1.5 Oe at 300 K, for applied fields perpendicular and parallel to the c-axis, respectively. The value for TC is exceptionally high, and the coercive fields exceptionally low, among the known R-type ferrites. Enhanced coercivity and thermomagnetic hysteresis suggest the onset of short-range, spin glass order occurs below Tf = 35 K. Optical measurements indicate a band gap of 0.8 eV, consistent with wide-gap semiconducting behavior and a previously established empirical correlation between the semiconducting gap and TC for R-type ferrites based upon Ru.

Snow Densification and Recent Accumulation Along the iSTAR Traverse, Pine Island Glacier, Antarctica

NASA Astrophysics Data System (ADS)

Morris, E. M.; Mulvaney, R.; Arthern, R. J.; Davies, D.; Gurney, R. J.; Lambert, P.; De Rydt, J.; Smith, A. M.; Tuckwell, R. J.; Winstrup, M.

2017-12-01

Neutron probe measurements of snow density from 22 sites in the Pine Island Glacier basin have been used to determine mean annual accumulation using an automatic annual layer identification routine. A mean density profile which can be used to convert radar two-way travel times to depth has been derived, and the effect of annual fluctuations in density on estimates of the depth of radar reflectors is shown to be insignificant, except very near the surface. Vertical densification rates have been derived from the neutron probe density profiles and from deeper firn core density profiles available at 9 of the sites. These rates are consistent with the rates predicted by the Herron and Langway model for stage 1 densification (by grain-boundary sliding, grain growth and intracrystalline deformation) and stage 2 densification (predominantly by sintering), except in a transition zone extending from ≈8 to ≈13 m from the surface in which 10-14% of the compaction occurs. Profiles of volumetric strain rate at each site show that in this transition zone the rates are consistent with the Arthern densification model. Comparison of the vertical densification rates and volumetric strain rates indicates that the expected relation to mean annual accumulation breaks down at high accumulation rates even when corrections are made for horizontal ice velocity divergence.

Self-reported use of tobacco products in nine rural INDEPTH Health and Demographic Surveillance Systems in Asia

PubMed Central

Ashraf, Ali; Quaiyum, M.A.; Ng, Nawi; Van Minh, Hoang; Razzaque, Abdur; Masud Ahmed, Syed; Hadi, Abdullahel; Juvekar, Sanjay; Kanungsukkasem, Uraiwan; Soonthornthada, Kusol; Huu Bich, Tran

2009-01-01

Background Tobacco use is the most preventable cause of premature death and disability. Even though tobacco use is common in many Asian countries, reliable and comparable data on the burden imposed by tobacco use in this region are sparse, and surveillance systems to track trends are in their infancy. Objective To assess and compare the prevalence of tobacco use and its associated factors in nine selected rural sites in five Asian countries. Methods Tobacco use among 9,208 men and 9,221 women aged 25–64 years in nine Health and Demographic Surveillance System (HDSS) sites in five Asian countries of the INDEPTH Network were examined in 2005 as part of a broader survey of the major chronic non-communicable disease risk factors. All sites used a standardised protocol based on the WHO STEPS approach to risk factor surveillance; expanded questions of local relevance, including chewing tobacco, were also included. Multivariable logistic regression was used to assess demographic factors associated with tobacco use. Results Tobacco use, whether smoked or chewed, was common across all sites with some notable variations. More than 50% of men smoked daily; this applied to almost all age groups. Few women smoked daily in any of the sites. However, women were more likely to chew tobacco than men in all sites except Vadu in India. Tobacco use in men began in late adolescence in most of the sites and the number of cigarettes smoked daily ranged from three to 15. Use of both forms of tobacco, smoked and chewed, was associated with age, gender and education. Men were more likely to smoke compared to women, smoking increased with age in the four sites in Bangladesh but not in other sites and with low level of education in all the sites. Conclusion The prevalence of tobacco use, regardless of the type of tobacco, was high among men in all of these rural populations with tobacco use started during adolescence in all HDSS sites. Innovative communication strategies for behaviour change targeting adolescents in schools and adult men and women at work or at home, may create a mass awareness about adverse health consequences of tobacco smoking or chewing tobacco. Such efforts, to be effective, however, need to be supported by strong legislation and leadership. Only four of the five countries involved in this multi-site study have ratified the Framework Convention on Tobacco Control, and even where it has been ratified, implementation is uneven. PMID:20027256

Precipitation, streamflow, suspended-sediment, and water-quality data for the U.S. Army Garrison Fort Carson and Piñon Canyon Maneuver Site, Colorado, 1966–2015

USGS Publications Warehouse

Arnold, L.R.

2017-08-03

The U.S. Army Garrison Fort Carson (AGFC) and the Piñon Canyon Maneuver Site (PCMS) are facilities operated by the U.S. Department of the Army in southern Colorado. The U.S. Geological Survey, in cooperation with the U.S. Department of the Army, established a hydrologic and water-quality data-collection network at the AGFC in June 1978 and at the PCMS in October 1982. The data-collection networks are designed to assess the quantity and quality of water resources and monitor the effects of military training activities on streamflow and water quality. Two preexisting U.S. Geological Survey streamgages at the PCMS were incorporated into the data-collection network at the time it was established, providing periods of record that begin as early as 1966. This report presents and summarizes precipitation, streamflow, suspended-sediment, and water-quality data from 34 U.S. Geological Survey sites on or near the AGFC and the PCMS for the period of record at each site. (Streamflow data are presented as discharge in cubic feet per second.)At AGFC, daily sum precipitation ranged from 0 to 11.85 inches, daily mean discharge ranged from 0 to 836 cubic feet per second, and daily mean suspended-sediment discharge ranged from 0 to 39,900 tons per day. With the exception of total (unfiltered) mercury and filtered sulfate at two sites and filtered manganese at three sites, 95th percentile trace element concentrations and median total (unfiltered) metal concentrations were less than regulatory numeric standards for all samples. However, individual water-quality results occasionally exceeded respective regulatory numeric standards.At the PCMS, daily sum precipitation ranged from 0 to 4.59 inches, daily mean discharge ranged from 0 to 4,190 cubic feet per second, and daily mean suspended-sediment discharge ranged from 0 to 21,100 tons per day. Water-quality results, 95th percentile trace element concentrations, and median total (unfiltered) metal concentrations were less than regulatory numeric standards for most properties and constituents except for filtered chloride at one site, filtered sulfate at six sites, filtered phosphorus at one site, filtered manganese at three sites, and total (unfiltered) iron at three sites. Individual water-quality values also occasionally exceeded respective regulatory numeric standards.

37 CFR 202.2 - Copyright notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... may be on a container which is designed and can be expected to remain with the work; (11) The notice...) General. (1) With respect to a work published before January 1, 1978, copyright was secured, or the right to secure it was lost, except for works seeking ad interim copyright, at the date of publication, i.e...

20 CFR 416.960 - When we will consider your vocational background.

Code of Federal Regulations, 2013 CFR

2013-04-01

... applying for supplemental security income benefits based on disability, and we cannot decide whether you... in paragraphs (b) and (c) of this section. (b) Past relevant work. We will first compare our... work. See § 416.920(h) for an exception to this rule. (1) Definition of past relevant work. Past...

20 CFR 416.960 - When we will consider your vocational background.

Code of Federal Regulations, 2014 CFR

2014-04-01

... applying for supplemental security income benefits based on disability, and we cannot decide whether you... in paragraphs (b) and (c) of this section. (b) Past relevant work. We will first compare our... work. See § 416.920(h) for an exception to this rule. (1) Definition of past relevant work. Past...

5 CFR 890.102 - Coverage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... less. (2) An employee who is expected to work less than 6 months in each year, except for an employee who is employed under an OPM approved career-related work-study program under Schedule B of at least 1... time from the date of the first appointment to the completion of the work-study program. (3) An...

30 CFR 75.705 - Work on high-voltage lines; deenergizing and grounding.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Work on high-voltage lines; deenergizing and... Work on high-voltage lines; deenergizing and grounding. [Statutory Provisions] High-voltage lines, both..., except that repairs may be permitted, in the case of energized surface high-voltage lines, if such...

28 CFR 345.33 - Waiting list hiring exceptions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... position classification files. (b) Prior FPI work assignment. An inmate with prior FPI work experience during the inmate's current commitment and with no break in custody will ordinarily be placed within the... waiting lists, so there is no break in active duty with FPI. Such actions are also in order where the work...

28 CFR 345.33 - Waiting list hiring exceptions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... position classification files. (b) Prior FPI work assignment. An inmate with prior FPI work experience during the inmate's current commitment and with no break in custody will ordinarily be placed within the... waiting lists, so there is no break in active duty with FPI. Such actions are also in order where the work...

28 CFR 345.33 - Waiting list hiring exceptions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... position classification files. (b) Prior FPI work assignment. An inmate with prior FPI work experience during the inmate's current commitment and with no break in custody will ordinarily be placed within the... waiting lists, so there is no break in active duty with FPI. Such actions are also in order where the work...

38 CFR 3.350 - Special monthly compensation ratings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... that which would be equally well served by an amputation stump at the site of election below elbow or... amputation stump with prosthesis; for example: (a) Extremely unfavorable complete ankylosis of the knee, or... the conditions which follow: Amputation is a prerequisite except for loss of use of both arms and...

7 CFR 3560.58 - Site requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... rehabilitation of an existing structure located in the central business area of a rural community. With prior... located in residential areas as part of established rural communities, except as permitted in § 3560.58(b... area where a need for farm labor housing exists. (3) Communities in which Agency-financed MFH is...

77 FR 42197 - Small Business Size Standards: Construction

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-18

... ``exception'') under NAICS 237990, Other Heavy and Civil Engineering Construction, from $20 million to $30... available on its Web site at www.sba.gov/size for public review and comments. The ``Size Standards... developing, reviewing, and modifying size standards when necessary. SBA published the document on its Web...

43 CFR 8365.2-4 - Vehicles.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Vehicles. 8365.2-4 Section 8365.2-4 Public... OF THE INTERIOR RECREATION PROGRAMS VISITOR SERVICES Rules of Conduct § 8365.2-4 Vehicles. Unless otherwise authorized, no motor vehicle shall be driven within developed recreation sites or areas except on...

43 CFR 8365.2-4 - Vehicles.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Vehicles. 8365.2-4 Section 8365.2-4 Public... OF THE INTERIOR RECREATION PROGRAMS VISITOR SERVICES Rules of Conduct § 8365.2-4 Vehicles. Unless otherwise authorized, no motor vehicle shall be driven within developed recreation sites or areas except on...

43 CFR 8365.2-4 - Vehicles.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Vehicles. 8365.2-4 Section 8365.2-4 Public... OF THE INTERIOR RECREATION PROGRAMS VISITOR SERVICES Rules of Conduct § 8365.2-4 Vehicles. Unless otherwise authorized, no motor vehicle shall be driven within developed recreation sites or areas except on...

43 CFR 8365.2-4 - Vehicles.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Vehicles. 8365.2-4 Section 8365.2-4 Public... OF THE INTERIOR RECREATION PROGRAMS VISITOR SERVICES Rules of Conduct § 8365.2-4 Vehicles. Unless otherwise authorized, no motor vehicle shall be driven within developed recreation sites or areas except on...

7 CFR 210.7 - Reimbursement for school food authorities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... school food authorities. State agencies must: (A) Ensure that all certified school food authorities are...-site validation review; except that, all large school food authorities, as defined in § 210.18(b)(6... certification documentation. (vii) In years subsequent to the year certified, through School Year 2014-2015...

76 FR 44535 - Testing of Bisphenol A

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-26

... Web site is an ``anonymous access'' system, which means EPA will not know your identity or contact... INFORMATION: I. General Information A. Does this action apply to me? You may be potentially affected by this.... Paper recyclers (NAICS codes 322110, 322121, 3222), e.g., pulp mills, paper (except newsprint) mills...

37 CFR 360.3 - Form and content of claims.

Code of Federal Regulations, 2014 CFR

2014-07-01

... online in accordance with § 360.4(a)(1); and (iii) Upon request to the Copyright Royalty Board, Library... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.3 - Form and content of claims.

Code of Federal Regulations, 2011 CFR

2011-07-01

... online in accordance with § 360.4(a)(1); and (iii) Upon request to the Copyright Royalty Board, Library... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.3 - Form and content of claims.

Code of Federal Regulations, 2013 CFR

2013-07-01

... online in accordance with § 360.4(a)(1); and (iii) Upon request to the Copyright Royalty Board, Library... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

37 CFR 360.3 - Form and content of claims.

Code of Federal Regulations, 2012 CFR

2012-07-01

... online in accordance with § 360.4(a)(1); and (iii) Upon request to the Copyright Royalty Board, Library... claims submitted online through the Copyright Royalty Board Web site. (iv) The name, telephone number... representative of the copyright owner, except for claims filed online through the Copyright Royalty Board Web...

10 CFR 52.47 - Contents of applications; technical information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... accidents, e.g., challenges to containment integrity caused by core-concrete interaction, steam explosion... such as the service water intake structure and the ultimate heat sink; (2) An application for... design except for site-specific elements such as the service water intake structure and the ultimate heat...

10 CFR 52.47 - Contents of applications; technical information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... accidents, e.g., challenges to containment integrity caused by core-concrete interaction, steam explosion... such as the service water intake structure and the ultimate heat sink; (2) An application for... design except for site-specific elements such as the service water intake structure and the ultimate heat...

10 CFR 52.47 - Contents of applications; technical information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... accidents, e.g., challenges to containment integrity caused by core-concrete interaction, steam explosion... such as the service water intake structure and the ultimate heat sink; (2) An application for... design except for site-specific elements such as the service water intake structure and the ultimate heat...

10 CFR 52.47 - Contents of applications; technical information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... accidents, e.g., challenges to containment integrity caused by core-concrete interaction, steam explosion... such as the service water intake structure and the ultimate heat sink; (2) An application for... design except for site-specific elements such as the service water intake structure and the ultimate heat...

10 CFR 52.47 - Contents of applications; technical information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... accidents, e.g., challenges to containment integrity caused by core-concrete interaction, steam explosion... such as the service water intake structure and the ultimate heat sink; (2) An application for... design except for site-specific elements such as the service water intake structure and the ultimate heat...

Regional meteorological drivers and long term trends of winter-spring nitrate dynamics across watersheds in northeastern North America

USGS Publications Warehouse

Crossman, Jill; Eimers, M Catherine; Casson, Nora J.; Burns, Douglas A.; Campbell, John L.; Likens, Gene E; Mitchell, Myron J; Nelson, Sarah J.; Shanley, James B.; Watmough, Shaun A.; Webster, Kara L

2016-01-01

This study evaluated the contribution of winter rain-on-snow (ROS) events to annual and seasonal nitrate (N-NO3) export and identified the regional meteorological drivers of inter-annual variability in ROS N-NO3 export (ROS-N) at 9 headwater streams located across Ontario, Canada and the northeastern United States. Although on average only 3.3 % of annual precipitation fell as ROS during winter over the study period, these events contributed a significant proportion of annual and winter N-NO3 export at the majority of sites (average of 12 and 42 %, respectively); with the exception of the most northern catchment, where total winter precipitation was exceptionally low (average 77 mm). In years with a greater magnitude of ROS events, the timing of the peak N-NO3 export period (during spring melt) was redistributed to earlier in the year. Variability in ROS frequency and magnitude amongst sites was high and a generalised linear model demonstrated that this spatial variability could be explained by interactive effects between regional and site-specific drivers. Snowpack coverage was particularly important for explaining the site-specific ROS response. Specifically, ROS events were less common when higher temperatures eliminated snow cover despite increasing the proportion of winter rainfall, whereas ROS event frequency was greater at sites where sufficient snow cover remained. This research suggests that catchment response to changes in N deposition is sensitive to climate change; a vulnerability which appears to vary in intensity throughout the seasonally snow-covered temperate region. Furthermore, the sensitivity of stream N-NO3 export to ROS events and potential shifts (earlier) in the timing of N-NO3 export relative to other nutrients affect downstream nutrient stoichiometry and the community composition of phytoplankton and other algae.

Geological Impacts and Sedimentary Record of the February 27, 2010, Chile Tsunami-La Trinchera to Concepcion

USGS Publications Warehouse

Morton, Robert A.; Buckley, Mark L.; Gelfenbaum, Guy; Richmond, Bruce M.; Cecioni, Adriano; Artal, Osvaldo; Hoffmann, Constanza; Perez, Felipe

2010-01-01

The February 27, 2010, Chilean tsunami substantially altered the coastal landscape and left a permanent depositional record that may be preserved at many locales along the central coast of Chile. From April 24 to May 2, 2010, a team of U.S. Geological Survey (USGS) and Chilean scientists examined the geological impacts of the tsunami at five sites along a 200-km segment of coast centered on the earthquake epicenter. Significant observations include: (1) substantial tsunami-induced erosion and deposition (+/- 1 m) on the coastal plain; (2) erosion from return flow, inundation scour around the bases of trees, and widespread planation of the land surface; (3) tsunami sand deposits at all sites that extended to near the limit of inundation except at one site; (4) evidence of multiple strong onshore waves that arrived at different times and from different directions; (5) vegetation height and density controlled the thickness of tsunami deposits at one site, (6) the abundance of layers of plane-parallel stratification in some deposits and the presence of large bedforms at one site indicated at least some of the sediment was transported as bed load and not as suspended load; (7) shoreward transport of mud boulders and rock cobbles where they were available; and (8) the maximum tsunami inundation distance (2.35 km) was up an alluvial valley. Most of the tsunami deposits were less than 25 cm thick, which is consistent with tsunami-deposit thicknesses found elsewhere (for example, Papua New Guinea, Peru, Sumatra, Sri Lanka). Exceptions were the thick tsunami deposits near the mouths of Rio Huenchullami (La Trinchera) and Rio Maule (Constitucion), where the sediment supply was abundant. The substantial vertical erosion of the coastal plain at Constitucion

Survey of atmospheric total gaseous mercury in Mexico

NASA Astrophysics Data System (ADS)

de la Rosa, D. A.; Volke-Sepúlveda, T.; Solórzano, G.; Green, C.; Tordon, R.; Beauchamp, S.

2004-09-01

While sources of gaseous mercury (natural and anthropogenic) are well known, studies on atmospheric mercury concentrations in Mexico are new. In order to assess the total gaseous mercury (TGM) levels at some characteristic Mexican sites, four locations were selected to start an exploratory survey and begin to asses the TGM behavior. This paper presents data obtained at an urban site (Mexico City), a rural site (Huejutla, Hidalgo), a coastline site (Puerto Angel, Oaxaca) and a closed mining site (Zacatecas City, Zacatecas). The highest TGM average values were found at this last site (71.82 ng m-3) together with the urban site (9.81 ng m-3). At the rural and coast line sites the lowest TGM values (1.32 and 1.46 ng m-3, respectively) were found. According to the ANOVA test, there were significant differences for the TGM values among all the studied sites, except between the coastline and the rural place. A multiple correlation test performed between TGM and some meteorological parameters showed that in sites without anthropogenic mercury sources influence (rural and coast line), the TGM levels are correlated with the temperature and relative humidity, while for the other two sites no clear correlation was found.

AmeriFlux US-Ha2 Harvard Forest Hemlock Site

DOE Data Explorer

Munger, William [Harvard University

2016-01-01

This is the AmeriFlux version of the carbon flux data for the site US-Ha2 Harvard Forest Hemlock Site. Site Description - The forest surrounding the Hemlock site has remained pristine with two exceptions. In the early to mid-1700s, European settlers cleared the majority of the forest for agricultural purposes. Selective harvesting of hemlock and chestnut trees occurred up until the early 1900s, when the chestnut blight killed all of the chestnut trees. In the current forest, about 83% of the total basal area of trees is hemlock. The remainder is equally divided between eastern white pine (Pinus strobus L.) and deciduous species, including red maple (Acer rubrum), red oak (Quercus rubra) and black birch (Betula lenta). A very thick organic layer (10-20 cm or more) covers the soil surface, and highly decayed coarse woody debris is abundant.

ADSORPTION AND DISSOCIATION OF O2 ON Ti3Al (0001) STUDIED BY FIRST-PRINCIPLES

NASA Astrophysics Data System (ADS)

Wei, Li-Jing; Guo, Jian-Xin; Dai, Xiu-Hong; Wang, Ying-Long; Liu, Bao-Ting

2015-05-01

The adsorption and dissociation of oxygen molecule on Ti3Al (0001) surface have been investigated by density functional theory (DFT) with the generalized gradient approximation (GGA). All possible adsorption sites including nine vertical and fifteen parallel sites of O2 are considered on Ti3Al (0001) surface. It is found that all oxygen molecules dissociate except for three vertical adsorption sites after structure optimization. This indicates that oxygen molecules prefer to dissociate on the junction site between Ti and Al atoms. Oxygen atoms coming from dissociation of oxygen molecule tend to occupy the most stable adsorption sites of the Ti3Al (0001) surface. The distance of O-O is related to the surface dissociation distance of Ti3Al (0001) surface. The valence electron localization function (ELF) and projected density of states (DOS) show that the bonds of O-O are breakaway at parallel adsorption end structures.

Reaching the poor with health interventions: programme-incidence analysis of seven randomised trials of women's groups to reduce newborn mortality in Asia and Africa.

PubMed

Houweling, Tanja A J; Morrison, Joanna; Alcock, Glyn; Azad, Kishwar; Das, Sushmita; Hossen, Munir; Kuddus, Abdul; Lewycka, Sonia; Looman, Caspar W; Magar, Bharat Budhathoki; Manandhar, Dharma S; Akter, Mahfuza; Dube, Albert Lazarous Nkhata; Rath, Shibanand; Saville, Naomi; Sen, Aman; Tripathy, Prasanta; Costello, Anthony

2016-01-01

Efforts to end preventable newborn deaths will fail if the poor are not reached with effective interventions. To understand what works to reach vulnerable groups, we describe and explain the uptake of a highly effective community-based newborn health intervention across social strata in Asia and Africa. We conducted a secondary analysis of seven randomised trials of participatory women's groups to reduce newborn mortality in India, Bangladesh, Nepal and Malawi. We analysed data on 70,574 pregnancies. Socioeconomic and sociodemographic differences in group attendance were tested using logistic regression. Qualitative data were collected at each trial site (225 focus groups, 20 interviews) to understand our results. Socioeconomic differences in women's group attendance were small, except for occasional lower attendance by elites. Sociodemographic differences were large, with lower attendance by young primigravid women in African as well as in South Asian sites. The intervention was considered relevant and interesting to all socioeconomic groups. Local facilitators ensured inclusion of poorer women. Embarrassment and family constraints on movement outside the home restricted attendance among primigravid women. Reproductive health discussions were perceived as inappropriate for them. Community-based women's groups can help to reach every newborn with effective interventions. Equitable intervention uptake is enhanced when facilitators actively encourage all women to attend, organise meetings at the participants' convenience and use approaches that are easily understandable for the less educated. Focused efforts to include primigravid women are necessary, working with families and communities to decrease social taboos. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Exploring the binding of 4-thiothymidine with human serum albumin by spectroscopy, atomic force microscopy, and molecular modeling methods.

PubMed

Zhang, Juling; Gu, Huaimin; Zhang, Xiaohui

2014-01-30

The interaction of 4-thiothymidine (S(4)TdR) with human serum albumin (HSA) was studied by equilibrium dialysis under normal physiological conditions. In this work, the mechanism of the interaction between S(4)TdR and human serum albumin (HSA) was exploited by fluorescence, UV, CD circular, and SERS spectroscopic. Fluorescence and UV spectroscopy suggest that HSA intensities are significantly decreased when adding S(4)TdR to HAS, and the quenching mechanism of the fluorescence is static. Also, the ΔG, ΔH, and ΔS values across temperature indicated that hydrophobic interaction was the predominant binding force. The CD circular results show that there is little change in the secondary structure of HSA except the environment of amino acid changes when adding S(4)TdR to HSA. The surface-enhanced Raman scattering (SERS) shows that the interaction between S(4)TdR and HSA can be achieved through different binding sites which are probably located in the II A and III A hydrophobic pockets of HSA which correspond to Sudlow's I and II binding sites. In addition, the molecular modeling displays that S(4)TdR-HSA complex is stabilized by hydrophobic forces, which result from amino acid residues. The atomic force microscopy results revealed that the single HSA molecular dimensions were larger after interaction of 4-thiothymidine. This work would be useful to understand the state of the transportation, distribution, and metabolism of the anticancer drugs in the human body, and it could provide a useful biochemistry parameter for the development of new anti-cancer drugs and research of pharmacology mechanisms. Copyright © 2013 Elsevier Ltd. All rights reserved.

Comparability of river quality assessment using macrophytes: a multi-step procedure to overcome biogeographical differences.

PubMed

Aguiar, F C; Segurado, P; Urbanič, G; Cambra, J; Chauvin, C; Ciadamidaro, S; Dörflinger, G; Ferreira, J; Germ, M; Manolaki, P; Minciardi, M R; Munné, A; Papastergiadou, E; Ferreira, M T

2014-04-01

This paper exposes a new methodological approach to solve the problem of intercalibrating river quality national methods when a common metric is lacking and most of the countries share the same Water Framework Directive (WFD) assessment method. We provide recommendations for similar works in future concerning the assessment of ecological accuracy and highlight the importance of a good common ground to make feasible the scientific work beyond the intercalibration. The approach herein presented was applied to highly seasonal rivers of the Mediterranean Geographical Intercalibration Group for the Biological Quality Element Macrophytes. The Mediterranean Group of river macrophytes involved seven countries and two assessment methods with similar acquisition data and assessment concept: the Macrophyte Biological Index for Rivers (IBMR) for Cyprus, France, Greece, Italy, Portugal and Spain, and the River Macrophyte Index (RMI) for Slovenia. Database included 318 sites of which 78 were considered as benchmarks. The boundary harmonization was performed for common WFD-assessment methods (all countries except Slovenia) using the median of the Good/Moderate and High/Good boundaries of all countries. Then, whenever possible, the Slovenian method, RMI was computed for the entire database. The IBMR was also computed for the Slovenian sites and was regressed against RMI in order to check the relatedness of methods (R(2)=0.45; p<0.00001) and to convert RMI boundaries into the IBMR scale. The boundary bias of RMI was computed using direct comparison of classification and the median boundary values following boundary harmonization. The average absolute class differences after harmonization is 26% and the percentage of classifications differing by half of a quality class is also small (16.4%). This multi-step approach to the intercalibration was endorsed by the WFD Regulatory Committee. © 2013 Elsevier B.V. All rights reserved.

Are glacials "dry" - and in what sense?

NASA Astrophysics Data System (ADS)

Scheff, J.; Seager, R.; Coats, S.; Liu, H.

2016-12-01

Glacial maxima during the Pleistocene are generally thought to be arid on land, with a few regional exceptions. Recent work on future climate change, however, has found that different wetness-related variables have opposite-signed responses over large portions of the continents, belying simple ideas of local "drying" or "wetting" with global temperature change in models. Here, we show that this behavior extends to simulations of the Last Glacial Maximum as well: the continents are modeled to have generally wetter topsoils and higher values of standard climate-wetness metrics in the LGM than in the preindustrial, as well as generally lower precipitation and ubiquitously lower photosynthesis (likely driven by the low CO2), with the streamflow response falling in between. Is this model-derived view of the LGM an accurate one? Using a large community pollen and plant-fossil compilation, we confirm that LGM grasslands and open woodlands grew at many sites of present potential forest, seasonal or dry forests at many sites of present potential rain- or seasonal forests, and so forth, while changes in the opposite sense were extremely few and spatially confined. We show that this strongly resembles the simulated photosynthesis changes, but not the simulated streamflow or soil moisture changes. Meanwhile, published LGM lake-level estimates resemble the simulated streamflow changes, but not the photosynthesis changes. Thus, the last glacial does not appear to be systematically "dry" outside the high latitudes, but merely carbon-starved. Similarly, local findings of reduced or more open vegetation at the LGM (e.g. from pollen, carbon isotopes, or dustiness) do not indicate local "aridity" unless corroborating hydrological proxies are also found. Finally, this work suggests that glacial-era evidence of open vegetation with high lake levels (as in the eastern Mediterranean) is not odd or paradoxical, but entirely consistent with climate model output.

Local rectification of heat flux

NASA Astrophysics Data System (ADS)

Pons, M.; Cui, Y. Y.; Ruschhaupt, A.; Simón, M. A.; Muga, J. G.

2017-09-01

We present a chain-of-atoms model where heat is rectified, with different fluxes from the hot to the cold baths located at the chain boundaries when the temperature bias is reversed. The chain is homogeneous except for boundary effects and a local modification of the interactions at one site, the “impurity”. The rectification mechanism is due here to the localized impurity, the only asymmetrical element of the structure, apart from the externally imposed temperature bias, and does not rely on putting in contact different materials or other known mechanisms such as grading or long-range interactions. The effect survives if all interaction forces are linear except the ones for the impurity.

Draft Site Management and Monitoring Plan for Corpus Christi Maintenance and New Work Ocean Dredged Material Disposal Site

EPA Pesticide Factsheets

USEPA Region 6 and the US Army Corps of Engineers submit for public comment the Draft Site Management and Monitoring Plan for Corpus Christi Maintenance and New Work Ocean Dredged Material Disposal Site

Debris exhaust system

DOEpatents

McBride, Donald D.; Bua, Dominic; Domankevitz, Yacov; Nishioka, Norman

1998-01-01

A debris removal system removes debris from a work site by flowing fluid away from the work site toward the periphery of a structure. The fluid flow can be kept constant around the periphery so that debris is removed evenly. The structure can have a reduced cross section between the fluid inlet and the work site so that the resulting increased fluid velocity works to prevent debris from escaping.

76 FR 46305 - Eligibility Criteria for Sites Recruiting National Health Service Corps Scholars

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-02

... 4 work days per week, with no more than 12 hours of work to be performed in any 24-hour period. Time... may be compressed into no less than 2 work days per week, with no more than 12 hours of work to be...-approved service site(s), during normally scheduled office hours. The remaining 4 hours per week must be...

Debris exhaust system

DOEpatents

McBride, D.D.; Bua, D.; Domankevitz, Y.; Nishioka, N.

1998-06-23

A debris removal system removes debris from a work site by flowing fluid away from the work site toward the periphery of a structure. The fluid flow can be kept constant around the periphery so that debris is removed evenly. The structure can have a reduced cross section between the fluid inlet and the work site so that the resulting increased fluid velocity works to prevent debris from escaping. 9 figs.

24 CFR 200.47 - Firm commitments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... work, except as deferred by the Commissioner in accordance with terms, conditions and standards... section, and for the insurance of mortgage money advanced in accordance with terms and conditions established by the Commissioner during: construction; substantial rehabilitation; or other work acceptable to...

Wind-related resuspension of sediments in the Peel-Harvey Estuarine System

NASA Astrophysics Data System (ADS)

Gabrielson, J. O.; Lukatelich, R. J.

1985-02-01

Resuspension of bottom sediments accounted for 69-92% of mean deposition rates (11·6-69·3 gm -2 day -1) measured at 5 sites in the Peel-Harvey Estuarine System, Western Australia. Deposition rates at all but one of the sites were found to be correlated ( P<0·05) with a function of wind combining a fetch factor with the number of hours of winds greater than 5 ms -1 weighted by the third power of wind velocity. The exception was the only site with a cover of benthic algae ( Cladophora) during the study. Wind-related resuspension greatly affects the forms and amounts of productivity in this system.

A Review of Optical Sky Brightness and Extinction at Dome C, Antarctica

NASA Astrophysics Data System (ADS)

Kenyon, S. L.; Storey, J. W. V.

2006-03-01

The recent discovery of exceptional seeing conditions at Dome C, Antarctica, raises the possibility of constructing an optical observatory there with unique capabilities. However, little is known from an astronomer's perspective about the optical sky brightness and extinction at Antarctic sites. We review the contributions to sky brightness at high-latitude sites and calculate the amount of usable dark time at Dome C. We also explore the implications of the limited sky coverage of high-latitude sites and review optical extinction data from the South Pole. Finally, we examine the proposal of Baldry & Bland-Hawthorn to extend the amount of usable dark time through the use of polarizing filters.

LCR 5′ hypersensitive site specificity for globin gene activation within the active chromatin hub

PubMed Central

Peterson, Kenneth R.; Fedosyuk, Halyna; Harju-Baker, Susanna

2012-01-01

The DNaseI hypersensitive sites (HSs) of the human β-globin locus control region (LCR) may function as part of an LCR holocomplex within a larger active chromatin hub (ACH). Differential activation of the globin genes during development may be controlled in part by preferential interaction of each gene with specific individual HSs during globin gene switching, a change in conformation of the LCR holocomplex, or both. To distinguish between these possibilities, human β-globin locus yeast artificial chromosome (β-YAC) lines were produced in which the ε-globin gene was replaced with a second marked β-globin gene (βm), coupled to an intact LCR, a 5′HS3 complete deletion (5′ΔHS3) or a 5′HS3 core deletion (5′ΔHS3c). The 5′ΔHS3c mice expressed βm-globin throughout development; γ-globin was co-expressed in the embryonic yolk sac, but not in the fetal liver; and wild-type β-globin was co-expressed in adult mice. Although the 5′HS3 core was not required for βm-globin expression, previous work showed that the 5′HS3 core is necessary for ε-globin expression during embryonic erythropoiesis. A similar phenotype was observed in 5′HS complete deletion mice, except βm-globin expression was higher during primitive erythropoiesis and γ-globin expression continued into fetal definitive erythropoiesis. These data support a site specificity model of LCR HS-globin gene interaction. PMID:23042246

Effects of Offshore Oil Exploration and Development in the Alaskan Beaufort Sea: A Three-Decade Record for Sediment Metals.

PubMed

Trefry, John H; Neff, Jerry M

2018-06-19

Impacts from oil exploration, development and production in the Beaufort Sea, Alaska, are assessed using concentrations of metals in sediments collected during 2014-15, combined with a large dataset for 1985-2006. Concentrations of 7 (1980 s) or 17 (1999-2015) metals in 423 surface sediments from 134 stations, plus 563 samples from 30 cores were highly variable, primarily as a function of sediment granulometry with naturally greater metal concentrations in fine-grained, Al-rich sediment. Metals versus Al correlation plots were used to normalize metal concentrations and identify values significantly above background. Barium, Cr, Cu, Hg and Pb concentrations were above background, but variable, within 250 m of some offshore sites where drilling occurred between 1981-2001; these areas totaled <6 km 2 of 11,000 km 2 in the total lease area. Random and fixed sampling along the coastal Beaufort Sea from 1985-2015 yielded 40 positive anomalies for metals in surface sediments (∼0.8% of 5,082 data points). About 85% of the anomalies were from developed areas. Half the anomalies were for the five metals found enhanced near drilling sites. No metals concentrations, except As, exceeded accepted sediment quality criteria. Interannual shifts in metals values for surface sediments at inner shelf sites were common and linked to storm-induced transitions in granulometry; however, metal/Al ratios were uniform during these shifts. Sediment cores generally recorded centuries of background values, except for As, Fe and Mn. These three metals were naturally enriched in sediments from deeper water (>100 m) via diagenetic remobilization at sediment depths of 5-15 cm, upward diffusion, and precipitation in surface oxic layers. Minimal evidence for anthropogenic inputs of metals, except near some exploratory drilling sites, is consistent with extraction of most oil from land or barrier islands in the Alaskan Arctic and restricted offshore activity to date. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Contrast in the Photoelectric Effect of Organic and Biochemical Surfaces

PubMed Central

Birrell, G. B.; Burke, C.; Dehlinger, P.; Griffith, O. H.

1973-01-01

The photoelectric effect can provide the physical basis for a new method of mapping organic and biological surfaces. The technique, photoelectron microscopy, is similar to fluorescence microscopy using incident ultraviolet light except that photoejected electrons form the image of the specimen surface. In this work the minimum wavelengths of incident light required to produce an image were determined for the molecules 3,6-bis(dimethylamino)acridine (acridine orange) (I), benzo[a]pyrene (II), N,N,N′,N′-tetraphenylbenzidine (III), and copper phthalocyanine (IV). The photoelectron image thresholds for these compounds are 220 (I), 215 (II), 220 (III), and 240 nm (IV), all ±5 nm. Contrast of I-IV with respect to typical protein, lipid, nucleic acid, and polysaccharide surfaces was examined over the wavelength range 240-180 nm. The low magnification micrographs exhibited bright areas corresponding to I-IV but dark regions for the biochemical surfaces. The high contrast suggests the feasibility of performing extrinsic photoelectron microscopy experiments through selective labeling of sites on biological surfaces. ImagesFIGURE 3 PMID:4704486

Bibliography of U.S. Geological Survey reports on the water resources of Florida, 1886-1982

USGS Publications Warehouse

Claiborne, Maude; Nierstheimer, L.O.; Hoy, N.D.

1983-01-01

The U.S. Geological Survey (USGS) has been making investigations of the water resources of Florida since the latter part of the 19th century. Early work consisted mainly of data collection at a few spring and river sites at intermittent intervals with the exception of a statewide groundwater study made during 1910-12. In 1930, an office was established for surface water studies in Florida and in 1938 for groundwater studies. Since 1930, practically all of the water resources investigations made by USGS have been in cooperation with State and local agencies. The third edition, ' Bibliography of U.S. Geological Survey Reports on the Water Resources of Florida, 1886-1982 ' includes reports approved for release in calendar years 1981 and 1982. In addition to updating the second edition (1981) several reports released prior to that time, which were inadvertently omitted, have been added. The bibliographic list of publications is arranged alphabetically by senior author. The publications are also indexed by geographic area and by subject. (Lantz-PTT)

[Components and assembly of RNA-induced silencing complex].

PubMed

Song, Xue-Mei; Yan, Fei; Du, Li-Xin

2006-06-01

Degradation of homologous RNA in RNA interference is carried out by functional RNA-induced silencing complex (RISC). RISC contains Dicer, Argonaute proein, siRNA and other components. Researching structures and functions of these components is primary important for understanding assembly and functional mechanism of RISC, as well as the whole RNAi pathway. Recent research works showed that Dicer, containing RNaseIII domain, is responsible for production of siRNA at the beginning of RNAi, and guarantees the stability of RISC intermediate in assembly process. As the core component of RISC, Argonaute protein functions as slicer to cleave target RNA and offers the binding site of siRNA in RISC assembly, which are depended on PIWI domain and PAZ domain separately. Although there is only one strand of siRNA that is the guider of RISC, the double stranded structural character of siRNA is determinant of RNAi. Except those, there are still other components with unknown functions in RISC. The knowledge about RISC components and assembly now, is basis of a presumed RISC assembly model.

Passive samplers and community science in regional air quality measurement, education and communication.

PubMed

DeForest Hauser, Cindy; Buckley, Alexandra; Porter, Juliana

2015-08-01

Charlotte, in Mecklenburg County, North Carolina, was ranked in the top ten cities with the worst air quality for ozone in the United States by the American Lung Association from 2009 to 2011. Nearby counties that may experience similar air quality do not have state or county monitors. This study utilized NOx and ozone Ogawa passive samplers and community scientists to monitor air quality in five counties surrounding Charlotte and increase public engagement in air quality issues. Community scientists deployed samplers weekly at a residential site within each county. Samples were analyzed using spectrophotometry and ion chromatography. Elevated NOx concentrations were observed in four of the five counties relative to those with existing monitors. Ozone concentrations showed little county to county variation, except Iredell and Cabarrus which had higher concentrations than Rowan. Community involvement in this work led to an increase in local dissemination of the results, thus increasing air quality awareness. Copyright © 2014 Elsevier Ltd. All rights reserved.

Narrowband Angular Reflectance Properties of the Alkali Flats at White Sands, New Mexico

NASA Technical Reports Server (NTRS)

Whitlock, Charles H.; LeCroy, Stuart R.; Wheeler, Robert J.

1994-01-01

Results from helicopter measurements of the angular properties of surface reflectance for the alkali flats regions of the White Sands Missile Range are presented for the wavelength interval of 0.4 to 0.85 microns. This work was performed to allow accurate radiative transfer calculations over the region. Detailed tables and interpolation equations are given that permit other investigators to perform satellite calibrations over the alkali flats site. The effects of wavelength and soil moisture on narrowband angular reflectance are also investigated. Although there is a spectral variation in surface albedo, there is little spectral effect in Anisotropic Factor except in the forward scattering peak at solar zenith angles greater than 60 deg. The magnitude of the forward-scattering peak is also sensitive to soil moisture, with wet conditions causing a larger peak. The significance of this result is that angular reflectance properties at the center of the alkali flats usually will be different than those at the flats edge because moisture differences typically exist.

New peptidomimetics of insulin.

PubMed

Maslov, D L; Lokhov, P G; Abakumova, O Yu; Tsvetkova, T A; Prozorovskiy, V N

2002-08-01

New peptidomimetics that have been obtained in the course of our experimental work show distinct insulin-like activity both in vitro and in vivo. The first peptidomimetic (PM 1) is essentially a decapeptide in which sites of A (20-21) and B (19-26) chains of insulin are linked by the peptides bond (Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Cys-Asn). The second peptidomimetic (PM 2) has similar set of amino acid residues, except that two aromatic amino acids corresponding to the residues of B chain of insulin (B24 and B26) have been replaced with their D optical isomers (Cys-Gly-Glu-Arg-Gly-DPhe-Phe-DTyr-Cys-Asn). The third peptidomimetic (PM 3) has been obtained through acylation of N-terminal of PM 1 by the use of palmitic acid. The peptidomimetic incorporating D aromatic amino acids (PM 2) was demonstrated to exhibit more pronounced hypoglycemic impact, while the acylation of decapeptide tends to prolong the effective time of peptidomimetic influence in vivo.

After the War: Stories of the women who did scientific and technical work on the Manhattan Project

NASA Astrophysics Data System (ADS)

Howes, Ruth

2014-03-01

When the Japanese surrendered on September 2, 1945, the crash research program of the Manhattan Project abruptly ended although the labs continued to produce nuclear weapons to supplement the single implosion bomb ready for deployment. The older (over 25) members of the scientific staff at Los Alamos and other Manhattan Project sites were eager to return to jobs at universities and in industry, and the younger staff members wanted to finish graduate degrees. Women were no exception to this rule. In addition, the government launched a huge propaganda effort to persuade women to leave the workforce and make jobs available for returning GIs. Doors that had been open to women scientists and technicians abruptly closed as the economy returned to a peacetime footing. Stories of the women scientists and technicians of the Manhattan Project illustrate the strategies they used to meet these challenges as well as their remarkable determination to continue their careers.

Organochlorines and heavy metals in 17-year cicadas pose no apparent dietary threat to birds

USGS Publications Warehouse

Clark, D.R.

1992-01-01

Organochlorine and heavy metal concentrations in 17-year cicadas from Prince Georges and Anne Arundel Counties, Maryland, were well below levels known to be harmful to birds. Cicadas contained concentrations of metals similar to or less than other local invertebrates except they contained more copper than did earthworms. Copper and lead concentrations in cicadas from one site may have been elevated by sewage plant effluent deposited during river floodings. Cicadas from the median of a major highway did not contain more lead than cicadas from non-traffic sites.

Secure Distributed Processing Systems: Quarterly Technical Reports, 1 July 1977 - 30 April 1978

DTIC Science & Technology

1978-06-01

choice does not assure that the network is encrypted. Thus, process - process encryption seems to be the highest safe choice . The details of the...site, except for the one where the LC is located, there is a local l°ck^f^16^ n r Those processes are responsible for ia^tainlnTa ?ocal copy of the...ed into the LOCK table at every site in a subsequent phase of the recovery process In ^nmary, the LOR B«ohanlsm amounts to electing a neH LC for

The ARM Best Estimate Station-based Surface (ARMBESTNS) Data set

DOE Data Explorer

Qi,Tang; Xie,Shaocheng

2015-08-06

The ARM Best Estimate Station-based Surface (ARMBESTNS) data set merges together key surface measurements from the Southern Great Plains (SGP) sites. It is a twin data product of the ARM Best Estimate 2-dimensional Gridded Surface (ARMBE2DGRID) data set. Unlike the 2DGRID data set, the STNS data are reported at the original site locations and show the original information, except for the interpolation over time. Therefore, users have the flexibility to process the data with the approach more suitable for their applications.

Task delegation to physician extenders--some comparisons.

PubMed Central

Glenn, J K; Goldman, J

1976-01-01

This study uses a task delegation questionnaire to compare 1973 physician extender practices in seven primary care-oriented sites with a physician attitude survey made in 1969. One additional site using no physician extenders was included as a control. The study involves both major types of physician extenders (physician assistants and nurse practitioners) in ambulatory practices with at least one year of experience in using such personnel. With minor exceptions, actual task delegation patterns conform with the 1969 attitudes of physicians as to which tasks "could and should" be delegated to physician extenders. PMID:2022

ADAPTED PHYSICAL EDUCATION, PRINCIPLES AND PRACTICE OF PHYSICAL EDUCATION FOR EXCEPTIONAL STUDENTS. SECOND EDITION.

ERIC Educational Resources Information Center

DANIELS, ARTHUR S.; DAVIES, EVELYN A.

THIS BOOK HAS THREE PURPOSES--(1) TO SHOW HOW PHYSICAL EDUCATION ACTIVITIES MAY BE ADAPTED FOR EXCEPTIONAL STUDENTS AT ALL LEVELS OF SCHOOL, (2) TO SERVE AS A PRACTICAL GUIDE TO PHYSICAL EDUCATION PERSONNEL WHO WISH TO WORK FOR FULL DEVELOPMENT OF EACH STUDENT, AND (3) TO SERVE AS A TEXT FOR STUDENTS IN TRAINING, TEACHERS, AND THERAPISTS. PART ONE…