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Sample records for exceptionally common major

  1. A common precursor to two major crab neurosecretory peptides.

    PubMed

    Stuenkel, E L

    1986-01-01

    The biosynthesis of proteins by the X-organ sinus gland (XOSG) neurosecretory system of the crab, Cardisoma carnifex was studied using the pulse-chase technique. Analysis of radioactive proteins following 2D-PAGE showed that during pulse incubations of less than or equal to 30 min a single predominant 14Kd prohormone was synthesized. With chase less than or equal to 3 hr the primary 14Kd protein was found to undergo differential and/or multiple post-translational modifications prior to its proteolytic cleavage. Increasing the chase to greater than 3 hr showed a shift in labeling from the 14Kd forms to 3 separate 6Kd proteins. Two of the 6Kd proteins were identified as crustacean hyperglycemic peptides (CHH). Similarity in protein labeling using [3H]leucine and [35S]cysteine suggest a second major peptide group, the H peptide, known to lack cysteine, is also contained within the 14Kd precursor. Peptide mapping of the 14Kd proteins and of unlabeled CHH and peptide H provide substantive evidence for this biosynthetic scheme. Thus, both the CHH and H peptide groups, which together constitute greater than 90% of the XOSG peptide content, in this species, arise from a common 14Kd precursor molecule.

  2. Exceptionally preserved North American Paleogene metatherians: adaptations and discovery of a major gap in the opossum fossil record.

    PubMed

    Sánchez-Villagra, Marcelo; Ladevèze, Sandrine; Horovitz, Inés; Argot, Christine; Hooker, Jeremy J; Macrini, Thomas E; Martin, Thomas; Moore-Fay, Scott; de Muizon, Christian; Schmelzle, Thomas; Asher, Robert J

    2007-06-22

    A major gap in our knowledge of the evolution of marsupial mammals concerns the Paleogene of the northern continents, a critical time and place to link the early history of metatherians in Asia and North America with the more recent diversification in South America and Australia. We studied new exceptionally well-preserved partial skeletons of the Early Oligocene fossil Herpetotherium from the White River Formation in Wyoming, which allowed us to test the relationships of this taxon and examine its adaptations. Herpetotheriidae, with a fossil record extending from the Cretaceous to the Miocene, has traditionally been allied with opossums (Didelphidae) based on fragmentary material, mainly dentitions. Analysis of the new material reveals that several aspects of the cranial and postcranial anatomy, some of which suggests a terrestrial lifestyle, distinguish Herpetotherium from opossums. We found that Herpetotherium is the sister group to the crown group Marsupialia and is not a stem didelphid. Combination of the new palaeontological data with molecular divergence estimates, suggests the presence of a long undocumented gap in the fossil record of opossums extending some 45Myr from the Early Miocene to the Cretaceous.

  3. Common Genetic and Environmental Influences on Major Depressive Disorder and Conduct Disorder

    ERIC Educational Resources Information Center

    Subbarao, Anjali; Rhee, Soo Hyun; Young, Susan E.; Ehringer, Marissa A.; Corley, Robin P.; Hewitt, John K.

    2008-01-01

    The evidence for common genetic and environmental influences on conduct disorder (CD) and major depressive disorder (MDD) in adolescents was examined. A sample of 570 monozygotic twin pairs, 592 dizygotic twin pairs, and 426 non-twin siblings, aged 12-18 years, was recruited from the Colorado Twin Registry. For the past year data, there was a…

  4. Resilience to Major Life Stressors Is Not as Common as Thought.

    PubMed

    Infurna, Frank J; Luthar, Suniya S

    2016-03-01

    We attempted to replicate findings that "most people are resilient" following three events: spousal loss, divorce, and unemployment. We applied growth mixture models to the same longitudinal data set that has previously been used to assert that resilience is ubiquitous. When using identical model specifications, as in prior studies, we found that resilient trajectories were most common, but the number of trajectories identified was different. When we relaxed two assumptions used in prior studies-that (a) all classes have similar variability in levels of postadversity adjustment and (b) there is no variability in changes within classes-we found that a resilience class was least common. Methodologically, our results show how findings on trajectories of change following major life stressors can vary substantially, depending on statistical model specifications. Conceptually, the results underscore the errors inherent in any categorical statements about "rates of resilience" among individuals confronted with major life stressors. Pragmatically, they underscore the dangers in recommending against prophylactic interventions (on the basis of one method of analyzing longitudinal data) for individuals who have experienced major life stressors. PMID:26993272

  5. Exceptionally High Representation of Burkholderia cepacia among B. cepacia Complex Isolates Recovered from the Major Portuguese Cystic Fibrosis Center▿

    PubMed Central

    Cunha, Mónica V.; Pinto-de-Oliveira, Ana; Meirinhos-Soares, Luís; Salgado, Maria José; Melo-Cristino, José; Correia, Susana; Barreto, Celeste; Sá-Correia, Isabel

    2007-01-01

    Burkholderia cepacia, a species found infrequently in cystic fibrosis (CF), was isolated from 85% of patients infected with bacteria of the B. cepacia complex that visited the major Portuguese CF center, in Lisbon, during 2003 to 2005. A detailed molecular analysis revealed that this was mainly due to two B. cepacia clones. These clones were indistinguishable from two strains isolated from intrinsically contaminated nonsterile saline solutions for nasal application, detected during routine market surveillance by the Portuguese Medicines and Health Products Authority. PMID:17360834

  6. Common volatiles are major attractants for neonate larvae of the specialist flea beetle Altica koreana (Coleoptera: Chrysomelidae)

    NASA Astrophysics Data System (ADS)

    Xue, Huai-Jun; Yang, Xing-Ke

    2008-07-01

    Olfactory stimuli play an important role in the host searching of larval phytophagous insects. Previous studies indicate that larvae that have to find feeding sites after hatching are generally attracted to host volatiles. However, there are few studies on the olfactory responses of neonate larvae to host volatiles in cases when those larvae hatched on the host plant. In the present study, we determined the olfactory responses of neonate larvae of the specialist flea beetle, Altica koreana Ogloblin, to host and six non-host plants, using a static-air “arena.” Larvae responded significantly to the host plant Potentilla chinensis Ser. and five of six non-host plants, compared to the control. Larvae did not prefer the host plant over the non-host plants (except Artemisia sp.) when offered a choice. Additionally, odours of a non-host plant, which were unattractive to neonate larvae, may have masked the attractive odour of the host plant. These results indicate that common volatiles can play a major role in attracting larvae of this specialist to plants, but attraction to such odours may not be the major mechanism of host choice.

  7. Exceptions to the rules of oil-spill behavior: Case studies of major oil spills of the past twenty years

    SciTech Connect

    Hayes, M.O.

    1994-11-01

    Studies of major oil spills over the past 20 yr have allowed an evolution of our understanding of how to respond to and remediate the environmental impacts from such spills. There have been a number of spills for which follow-up research has provided major turning points that allowed the development of certain rules of oil-spill behavior. For example, the spill of over 100,000 tons of crude oil by the tanker Urquiola on the coast of Spain in May 1976 demonstrated the importance of hydrodynamic energy level in natural cleanup processes. Research on the spill of over 200,000 tons of crude oil along the coast of France by the tanker Amoco Cadiz in March 1978 allowed a better understanding of the long-term effects of spilled oil on exposed tidal flats and salt marshes. The oil spilled by the tanker Exxon Valdez in Prince William Sound, Alaska, in March 1989 impacted many miles of gravel beaches, which were treated by a number of methods, including some innovative berm-relocation techniques. A thorough understanding of the coastal geomorphology and processes of the spill site was essential for the development of meaningful contingency and response plans. Research on the impacts of intertidal habitats of the coast of Saudi Arabia during the Gulf War spill of 1991 indicates that some previously held concepts on oil behavior and fate on shorelines must be revised. One of the best established rules of oil-spill behavior was that the depth of oil penetration on sand beaches and tidal flats increases with increasing sediment grain size. However, no such correlation was found on the Saudi Arabian coast, primarily due to the presence of secondary porosity (e.g., bubble sand, extensive burrows, and gypsum crystals). The oil penetrated to depths of tens of centimeters, even in fine sand, which has significantly slowed natural removal processes and weathering rates. These sediments remained heavily oiled with incipient asphalt pavements forming two years after the spill.

  8. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders

    PubMed Central

    Lotan, Amit; Fenckova, Michaela; Bralten, Janita; Alttoa, Aet; Dixson, Luanna; Williams, Robert W.; van der Voet, Monique

    2014-01-01

    Major neuropsychiatric disorders are highly heritable, with mounting evidence suggesting that these disorders share overlapping sets of molecular and cellular underpinnings. In the current article we systematically test the degree of genetic commonality across six major neuropsychiatric disorders—attention deficit hyperactivity disorder (ADHD), anxiety disorders (Anx), autistic spectrum disorders (ASD), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). We curated a well-vetted list of genes based on large-scale human genetic studies based on the NHGRI catalog of published genome-wide association studies (GWAS). A total of 180 genes were accepted into the analysis on the basis of low but liberal GWAS p-values (<10−5). 22% of genes overlapped two or more disorders. The most widely shared subset of genes—common to five of six disorders–included ANK3, AS3MT, CACNA1C, CACNB2, CNNM2, CSMD1, DPCR1, ITIH3, NT5C2, PPP1R11, SYNE1, TCF4, TENM4, TRIM26, and ZNRD1. Using a suite of neuroinformatic resources, we showed that many of the shared genes are implicated in the postsynaptic density (PSD), expressed in immune tissues and co-expressed in developing human brain. Using a translational cross-species approach, we detected two distinct genetic components that were both shared by each of the six disorders; the 1st component is involved in CNS development, neural projections and synaptic transmission, while the 2nd is implicated in various cytoplasmic organelles and cellular processes. Combined, these genetic components account for 20–30% of the genetic load. The remaining risk is conferred by distinct, disorder-specific variants. Our systematic comparative analysis of shared and unique genetic factors highlights key gene sets and molecular processes that may ultimately translate into improved diagnosis and treatment of these debilitating disorders. PMID:25414627

  9. Distinctive and common neural underpinnings of major depression, social anxiety, and their comorbidity.

    PubMed

    Hamilton, J Paul; Chen, Michael C; Waugh, Christian E; Joormann, Jutta; Gotlib, Ian H

    2015-04-01

    Assessing neural commonalities and differences among depression, anxiety and their comorbidity is critical in developing a more integrative clinical neuroscience and in evaluating currently debated categorical vs dimensional approaches to psychiatric classification. Therefore, in this study, we sought to identify patterns of anomalous neural responding to criticism and praise that are specific to and common among major depressive disorder (MDD), social anxiety disorder (SAD) and comorbid MDD-SAD. Adult females who met formal diagnostic criteria for MDD, SAD or MDD-SAD and psychiatrically healthy participants underwent functional magnetic resonance imaging as they listened to statements directing praise or criticism at them or at another person. MDD groups showed reduced responding to praise across a distributed cortical network, an effect potentially mediated by thalamic nuclei undergirding arousal-mediated attention. SAD groups showed heightened anterior insula and decreased default-mode network response to criticism. The MDD-SAD group uniquely showed reduced responding to praise in the dorsal anterior cingulate cortex. Finally, all groups with psychopathology showed heightened response to criticism in a region of the superior frontal gyrus implicated in attentional gating. The present results suggest novel neural models of anhedonia in MDD, vigilance-withdrawal behaviors in SAD, and poorer outcome in MDD-SAD. Importantly, in identifying unique and common neural substrates of MDD and SAD, these results support a formulation in which common neural components represent general risk factors for psychopathology that, due to factors that are present at illness onset, lead to distinct forms of psychopathology with unique neural signatures.

  10. Specific and common genes implicated across major mental disorders: a review of meta-analysis studies.

    PubMed

    Gatt, Justine M; Burton, Karen L O; Williams, Leanne M; Schofield, Peter R

    2015-01-01

    Major efforts have been directed at family-based association and case-control studies to identify the involvement of candidate genes in the major disorders of mental health. What remains unknown is whether candidate genes are associated with multiple disorders via pleiotropic mechanisms, and/or if other genes are specific to susceptibility for individual disorders. Here we undertook a review of genes that have been identified in prior meta-analyses examining specific genes and specific mental disorders that have core disruptions to emotional and cognitive function and contribute most to burden of illness- major depressive disorder (MDD), anxiety disorders (AD, including panic disorder and obsessive compulsive disorder), schizophrenia (SZ) and bipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD). A literature review was conducted up to end-March 2013 which included a total of 1519 meta-analyses across 157 studies reporting multiple genes implicated in one or more of the five disorders studied. A total of 134 genes (206 variants) were identified as significantly associated risk variants for MDD, AD, ADHD, SZ or BD. Null genetic effects were also reported for 195 genes (426 variants). 13 genetic variants were shared in common between two or more disorders (APOE e4, ACE Ins/Del, BDNF Val66Met, COMT Val158Met, DAOA G72/G30 rs3918342, DAT1 40-bp, DRD4 48-bp, SLC6A4 5-HTTLPR, HTR1A C1019G, MTHR C677T, MTHR A1298C, SLC6A4 VNTR and TPH1 218A/C) demonstrating evidence for pleiotrophy. Another 12 meta-analyses of GWAS studies of the same disorders were identified, with no overlap in genetic variants reported. This review highlights the progress that is being made in identifying shared and unique genetic mechanisms that contribute to the risk of developing several major psychiatric disorders, and identifies further steps for progress.

  11. A Next Generation Air Monitor: Combining Orion and ISS Requirements for a Common Major Constituent Analyzer

    NASA Technical Reports Server (NTRS)

    Burchfield, David E.; Tissandier, Michael; Hsein-ChiNiu, William; Lewis, John F.

    2012-01-01

    The Major Constituent Analyzer (MCA) is a mass spectrometer-based instrument designed to provide critical monitoring of six major atmospheric constituents; nitrogen, oxygen, hydrogen, carbon dioxide, methane, and water vapor on-board the International Space Station. The analyzer has been an integral part of the Environmental Control and Life Support System (ECLSS) since the station went on-line. The Orion Air Monitor (OAM) was derived from the MCA and heavily optimized for reduced mass, lower power, faster water vapor response, and maintenance-free operation. The resulting OAM is approximately the size of the analyzer portion of the MCA, orbital-replacement unit 02 (ORU 02), while incorporating the functions of three other modules: Data Processing and Communication (ORU 01), Verification Gas Assembly (ORU 08), and Low Voltage Power Supply (ORU 04). The overlap in MCA and OAM requirements makes it possible to derive a common Air Monitor design that spans both applications while minimally impacting the weight and power limits imposed by the Multipurpose Crew Vehicle (MPCV). Benefits to ISS include the retirement of ORUs 01, 04, and 08, reducing up-mass and eliminating EEE parts obsolescence issues through the extended ISS mission phases. Benefits to MPCV and future deployed habitats under the Constellation program include greater interchangeability across ECLSS subsystems. This paper discusses the results of the requirements development study, where a superset of ISS and Orion air monitoring requirements were distilled; evaluated against increases in OAM functionality, mass, and power; and traded-off where possible using simple operating mode modifications. A system architecture and preliminary design addressing the common requirements will be presented.

  12. A Next Generation Air Monitor: Combining Orion and ISS Requirements for a Common Major Constituent Analyzer

    NASA Technical Reports Server (NTRS)

    Burchfield, David E.; Tissandier, Michael; Niu, William Hsein-Chi; Lewis, John F.

    2013-01-01

    The Major Constituent Analyzer (MCA) is a mass spectrometer-based instrument designed to provide critical monitoring of six major atmospheric constituents; nitrogen, oxygen, hydrogen, carbon dioxide, methane, and water vapor on-board the International Space Station. The analyzer has been an integral part of the Environmental Control and Life Support System (ECLSS) since the station went on-line. The Orion Air Monitor (OAM) was derived from the MCA and heavily optimized for reduced mass, lower power, faster water vapor response, and maintenance-free operation. The resulting OAM is approximately the size of the analyzer portion of the MCA, orbital-replacement unit 02 (ORU 02), while incorporating the functions of three other modules: Data Processing and Communication (ORU 01), Verification Gas Assembly (ORU 08), and Low Voltage Power Supply (ORU 04). The overlap in MCA and OAM requirements makes it possible to derive a common Air Monitor design that spans both applications while minimally impacting the weight and power limits imposed by the Multipurpose Crew Vehicle (MPCV). Benefits to ISS include the retirement of ORUs 01, 04, and 08, reducing up-mass and eliminating EEE parts obsolescence issues through the extended ISS mission phases. Benefits to MPCV and future deployed habitats under the Constellation program include greater interchangeability across ECLSS subsystems. This paper discusses the results of the requirements development study, where a superset of ISS and Orion air monitoring requirements were distilled; evaluated against increases in OAM functionality, mass, and power; and traded-off where possible using simple operating mode modifications. A system architecture and preliminary design addressing the common requirements will be presented.

  13. Abnormal functional brain asymmetry in depression: evidence of biologic commonality between major depression and dysthymia.

    PubMed

    Bruder, Gerard E; Stewart, Jonathan W; Hellerstein, David; Alvarenga, Jorge E; Alschuler, Daniel; McGrath, Patrick J

    2012-04-30

    Prior studies have found abnormalities of functional brain asymmetry in patients having a major depressive disorder (MDD). This study aimed to replicate findings of reduced right hemisphere advantage for perceiving dichotic complex tones in depressed patients, and to determine whether patients having "pure" dysthymia show the same abnormality of perceptual asymmetry as MDD. It also examined gender differences in lateralization, and the extent to which abnormalities of perceptual asymmetry in depressed patients are dependent on gender. Unmedicated patients having either a MDD (n=96) or "pure" dysthymic disorder (n=42) and healthy controls (n=114) were tested on dichotic fused-words and complex-tone tests. Patient and control groups differed in right hemisphere advantage for complex tones, but not left hemisphere advantage for words. Reduced right hemisphere advantage for tones was equally present in MDD and dysthymia, but was more evident among depressed men than depressed women. Also, healthy men had greater hemispheric asymmetry than healthy women for both words and tones, whereas this gender difference was not seen for depressed patients. Dysthymia and MDD share a common abnormality of hemispheric asymmetry for dichotic listening.

  14. Measuring functional and quality of life outcomes following major head injury: common scales and checklists.

    PubMed

    Nichol, A D; Higgins, A M; Gabbe, B J; Murray, L J; Cooper, D J; Cameron, P A

    2011-03-01

    Traumatic brain injury (TBI) is a major public health issue, which results in significant mortality and long term disability. The profound impact of TBI is not only felt by the individuals who suffer the injury but also their care-givers and society as a whole. Clinicians and researchers require reliable and valid measures of long term outcome not only to truly quantify the burden of TBI and the scale of functional impairment in survivors, but also to allow early appropriate allocation of rehabilitation supports. In addition, clinical trials which aim to improve outcomes in this devastating condition require high quality measures to accurately assess the impact of the interventions being studied. In this article, we review the properties of an ideal measure of outcome in the TBI population. Then, we describe the key components and performance of the measurement tools most commonly used to quantify outcome in clinical studies in TBI. These measurement tools include: the Glasgow Outcome Scale (GOS) and extended Glasgow Outcome Scale (GOSe); Disability Rating Scale (DRS); Functional Independence Measure (FIM); Functional Assessment Measure (FAM); Functional Status Examination (FSE) and the TBI-specific and generic quality of life measures used in TBI patients (SF-36 and SF-12, WHOQOL-BREF, SIP, EQ-5D, EBIQ, and QOLIBRI).

  15. Common and distinct structural network abnormalities in major depressive disorder and borderline personality disorder.

    PubMed

    Depping, Malte S; Wolf, Nadine D; Vasic, Nenad; Sambataro, Fabio; Thomann, Philipp A; Wolf, R Christian

    2016-02-01

    Major depressive disorder (MDD) and borderline personality disorder (BPD) show substantial overlap in both affective symptom expression and in regional brain volume reduction. To address the specificity of structural brain change for the respective diagnostic category, we investigated structural networks in MDD and BPD to identify shared and distinct patterns of abnormal brain volume associated with these phenotypically related disorders. Using magnetic resonance imaging at 3 T, we studied 22 females with MDD, 17 females with BPD and without comorbid posttraumatic stress disorder, and 22 age-matched female healthy controls. We used “source-based morphometry” (SBM) to investigate naturally grouping patterns of gray matter volume variation (i.e. “structural networks”) and the magnitude of their expression between groups. SBM identified three distinct structural networks which showed a significant group effect (p b 0.05, FDR-corrected). A bilateral frontostriatal network showed reduced volume in MDD compared to both controls and BPD patients. A medial temporal/medial frontal network was found to be significantly reduced in BPD compared to both controls and MDD patients. Decreased cingulate and lateral prefrontal volume was found in both MDD and BPD when compared to healthy individuals. In MDD significant relationships were found between depressive symptoms and a cingulate/lateral prefrontal structural pattern. In contrast, overall BPD symptoms and impulsivity scores were significantly associated with medial temporal/medial frontal network volume. The data suggest both distinct and common patterns of abnormal brain volume in MDD and BPD. Alterations of distinct structural networks differentially modulate clinical symptom expression in these disorders.

  16. "We Are in This Together": Common Group Identity Predicts Majority Members' Active Acculturation Efforts to Integrate Immigrants.

    PubMed

    Kunst, Jonas R; Thomsen, Lotte; Sam, David L; Berry, John W

    2015-10-01

    Although integration involves a process of mutual accommodation, the role of majority groups is often downplayed to passive tolerance, leaving immigrants with the sole responsibility for active integration. However, we show that common group identity can actively involve majority members in this process across five studies. Study 1 showed that common identity positively predicted support of integration efforts; Studies 2 and 3 extended these findings, showing that it also predicted real behavior such as monetary donations and volunteering. A decrease in modern racism mediated the relations across these studies, and Studies 4 and 5 further demonstrated that it indeed mediated these effects over and above acculturation expectations and color-blindness, which somewhat compromised integration efforts. Moreover, the last two studies also demonstrated that common, but not dual, groups motivated integration efforts. Common identity appears crucial for securing majorities' altruistic efforts to integrate immigrants and, thus, for achieving functional multiculturalism.

  17. The Major Field Test in Business: A Direct Measure of Learning in Common Business Disciplines

    ERIC Educational Resources Information Center

    Simmons, Susan A.; Jones, Wesley M., Jr; Bolt, Cynthia E.

    2015-01-01

    Assurance of learning and its assessment are critical focal points in collegiate schools of business as programs strive to achieve or maintain Association to Advance Collegiate Schools of Business accreditation. Prior research suggests that student learning in business core disciplines can be measured by the Educational Testing Service Major Field…

  18. Major Histocompatibility Complex Based Resistance to a Common Bacterial Pathogen of Amphibians

    PubMed Central

    Barribeau, Seth M.; Villinger, Jandouwe; Waldman, Bruce

    2008-01-01

    Given their well-developed systems of innate and adaptive immunity, global population declines of amphibians are particularly perplexing. To investigate the role of the major histocompatibilty complex (MHC) in conferring pathogen resistance, we challenged Xenopus laevis tadpoles bearing different combinations of four MHC haplotypes (f, g, j, and r) with the bacterial pathogen Aeromonas hydrophila in two experiments. In the first, we exposed ff, fg, gg, gj, and jj tadpoles, obtained from breeding MHC homozygous parents, to one of three doses of A. hydrophila or heat-killed bacteria as a control. In the second, we exposed ff, fg, fr, gg, rg, and rr tadpoles, obtained from breeding MHC heterozygous parents and subsequently genotyped by PCR, to A. hydrophila, heat-killed bacteria or media alone as controls. We thereby determined whether the same patterns of MHC resistance emerged within as among families, independent of non-MHC heritable differences. Tadpoles with r or g MHC haplotypes were more likely to die than were those with f or j haplotypes. Growth rates varied among MHC types, independent of exposure dose. Heterozygous individuals with both susceptible and resistant haplotypes were intermediate to either homozygous genotype in both size and survival. The effect of the MHC on growth and survival was consistent between experiments and across families. MHC alleles differentially confer resistance to, or tolerance of, the bacterial pathogen, which affects tadpoles' growth and survival. PMID:18629002

  19. Major histocompatibility complex variation in red wolves: evidence for common ancestry with coyotes and balancing selection.

    PubMed

    Hedrick, P W; Lee, R N; Garrigan, D

    2002-10-01

    We examined variation at a class II major histocompatibility complex (MHC) gene (DRB1) in the captive red wolf population and samples of coyotes from Texas and North Carolina. We found 4 alleles in the 48 red wolves, 8 alleles in the 10 coyotes from Texas and 15 alleles in the 29 coyotes from North Carolina. Two of the four alleles found in red wolves, Caru-2 and Caru-4, were found in both the Texas and North Carolina coyote samples. Allele Caru-1, previously found in gray wolves, was also found in the North Carolina sample. The most frequent red wolf allele, Caru-3, was not found in any of the coyote samples. However, an allele found in both the Texas and North Carolina coyote samples is only one nucleotide (one amino acid) different from this red wolf allele. Overall, it appears from examination of this MHC gene that red wolves are more closely related to coyotes than to gray wolves. There were a number of different types of evidence supporting the action of balancing selection in red wolves. Namely, there was: (i) an excess of heterozygotes compared with expectations; (ii) a higher rate of nonsynonymous than synonymous substitution for the functionally important antigen-binding site positions; (iii) an eight times higher average heterozygosity of individual amino acids at the positions identified as part of the antigen-binding site than those not associated with it; (iv) the amino acid divergence of four red wolf alleles was greater than that expected from a simulation of genetic drift; and (v) the distribution of alleles, and the distributions of amino acids at many positions were more even than expected from neutrality. Examination of the level and pattern of linkage disequilibria between pairs of sites suggest that the heterozygosity, substitution and frequencies at individual amino acids are not highly dependent upon each other.

  20. Induction of a Major Leaf Acid Phosphatase Does Not Confer Adaptation to Low Phosphorus Availability in Common Bean1

    PubMed Central

    Yan, Xiaolong; Liao, Hong; Trull, Melanie C.; Beebe, Steve E.; Lynch, Jonathan P.

    2001-01-01

    Acid phosphatase is believed to be important for phosphorus scavenging and remobilization in plants, but its role in plant adaptation to low phosphorus availability has not been critically evaluated. To address this issue, we compared acid phosphatase activity (APA) in leaves of common bean (Phaseolus vulgaris) in a phosphorus-inefficient genotype (DOR364), a phosphorus-efficient genotype (G19833), and their F5.10 recombinant inbred lines (RILs). Phosphorus deficiency substantially increased leaf APA, but APA was much higher and more responsive to phosphorus availability in DOR364 than in G19833. Leaf APA segregated in the RILs, with two discrete groups having either high (mean = 1.71 μmol/mg protein/min) or low (0.36 μmol/mg protein/min) activity. A chi-square test indicated that the observed difference might be controlled by a single gene. Non-denaturing protein electrophoresis revealed that there are four visible isoforms responsible for total APA in common bean, and that the difference in APA between contrasting genotypes could be attributed to the existence of a single major isoform. Qualitative mapping of the APA trait and quantitative trait loci analysis with molecular markers indicated that a major gene contributing to APA is located on linkage group B03 of the unified common bean map. This locus was not associated with loci conferring phosphorus acquisition efficiency or phosphorus use efficiency. RILs contrasting for APA had similar phosphorus pools in old and young leaves under phosphorus stress, arguing against a role for APA in phosphorus remobilization. Our results do not support a major role for leaf APA induction in regulating plant adaptation to phosphorus deficiency. PMID:11299369

  1. Exceptional Stars

    NASA Astrophysics Data System (ADS)

    Kulkarni, S. R.; Hansen, B.; van Kerkwijk, M.; Phinney, E. S.

    2005-12-01

    As part of our Interdisciplinary Scientist effort (PI, Kulkarni) for the Space Interferometry Mission (SIM) we proposed an investigation with SIM of a number of exceptional stars. With SIM we plan to observe dozens of nearby white dwarfs and search for planets surviving the evolution away from the main sequence as well as (newly formed) planets formed in the circumbinary disks of post-AGB binaries or as a result of white dwarf mergers. We propose to measure the proper motion of a sample of X-ray binaries and Be star binaries with the view of understanding the originof high latitude objects and inferring natal kicks and pre-supernova orbits. We plan to observe several compact object binaries to determine the mass of the compact star. Of particular importance is the proposed observation of SS 433 (for which we propose to use the spectrometer on SIM to measure the proper motion of the emission line clumps embedded in the relativistic jets). Separately we are investigating the issue of frame tie between SIM and the ecliptic frame (by observing binary millisecond pulsars with SIM; the position of these objects is very well determined by pulsar timing) and the degree to which highly precise visibility amplitude measurements can be inverted to infer binary parameters.

  2. Identification, quantification, spatiotemporal distribution and genetic variation of major latex secondary metabolites in the common dandelion (Taraxacum officinale agg.).

    PubMed

    Huber, Meret; Triebwasser-Freese, Daniella; Reichelt, Michael; Heiling, Sven; Paetz, Christian; Chandran, Jima N; Bartram, Stefan; Schneider, Bernd; Gershenzon, Jonathan; Erb, Matthias

    2015-07-01

    The secondary metabolites in the roots, leaves and flowers of the common dandelion (Taraxacum officinale agg.) have been studied in detail. However, little is known about the specific constituents of the plant's highly specialized laticifer cells. Using a combination of liquid and gas chromatography, mass spectrometry and nuclear magnetic resonance spectrometry, we identified and quantified the major secondary metabolites in the latex of different organs across different growth stages in three genotypes, and tested the activity of the metabolites against the generalist root herbivore Diabrotica balteata. We found that common dandelion latex is dominated by three classes of secondary metabolites: phenolic inositol esters (PIEs), triterpene acetates (TritAc) and the sesquiterpene lactone taraxinic acid β-D-glucopyranosyl ester (TA-G). Purification and absolute quantification revealed concentrations in the upper mgg(-1) range for all compound classes with up to 6% PIEs, 5% TritAc and 7% TA-G per gram latex fresh weight. Contrary to typical secondary metabolite patterns, concentrations of all three classes increased with plant age. The highest concentrations were measured in the main root. PIE profiles differed both quantitatively and qualitatively between plant genotypes, whereas TritAc and TA-G differed only quantitatively. Metabolite concentrations were positively correlated within and between the different compound classes, indicating tight biosynthetic co-regulation. Latex metabolite extracts strongly repelled D. balteata larvae, suggesting that the latex constituents are biologically active. PMID:25682510

  3. Expanding upon the 'extreme male brain' theory of autism as a common link between other major risk factors: a hypothesis.

    PubMed

    Wen, Wendy; Wen, Shi Wu

    2014-05-01

    On average, males have a stronger preference for physical systems and machines over interpersonal interactions; they have lower average levels of cognitive empathy or social cognition than females; and they have higher rates of 'extreme' intelligence when it comes to abstract concepts such as those found in mathematics and sciences. All three traits are also commonly associated with individuals with an autism spectrum disorder or ASD; clearly, it is not coincidental that incidence rates of autism are reportedly four times higher in males than in females. The common link between the majority of risk factors assessed in this review (including technological advancements, advanced parental age, socioeconomic status, and genetic predispositions towards ASDs in families of scientists and engineers) can be traced to a specific hormone, testosterone. It was established that traits which are typically associated with males are also typically associated with ASDs as well as individuals with antisocial personality disorder, or APD. The key distinction between individuals who are considered to be 'autistic' as opposed to those who are considered 'sociopathic' lies in the difference between their empathy deficits: whereas those who are 'autistic' are said to lack cognitive empathy (the ability to identify and understand the thoughts and feelings of others and to respond to these with appropriate emotions), those who are 'sociopathic' are said to lack emotional empathy (which is responsible for inhibiting acts of physical aggression or violence). This would explain why autistic individuals can have elevated testosterone levels without becoming physically aggressive. PMID:24629356

  4. Identification, quantification, spatiotemporal distribution and genetic variation of major latex secondary metabolites in the common dandelion (Taraxacum officinale agg.).

    PubMed

    Huber, Meret; Triebwasser-Freese, Daniella; Reichelt, Michael; Heiling, Sven; Paetz, Christian; Chandran, Jima N; Bartram, Stefan; Schneider, Bernd; Gershenzon, Jonathan; Erb, Matthias

    2015-07-01

    The secondary metabolites in the roots, leaves and flowers of the common dandelion (Taraxacum officinale agg.) have been studied in detail. However, little is known about the specific constituents of the plant's highly specialized laticifer cells. Using a combination of liquid and gas chromatography, mass spectrometry and nuclear magnetic resonance spectrometry, we identified and quantified the major secondary metabolites in the latex of different organs across different growth stages in three genotypes, and tested the activity of the metabolites against the generalist root herbivore Diabrotica balteata. We found that common dandelion latex is dominated by three classes of secondary metabolites: phenolic inositol esters (PIEs), triterpene acetates (TritAc) and the sesquiterpene lactone taraxinic acid β-D-glucopyranosyl ester (TA-G). Purification and absolute quantification revealed concentrations in the upper mgg(-1) range for all compound classes with up to 6% PIEs, 5% TritAc and 7% TA-G per gram latex fresh weight. Contrary to typical secondary metabolite patterns, concentrations of all three classes increased with plant age. The highest concentrations were measured in the main root. PIE profiles differed both quantitatively and qualitatively between plant genotypes, whereas TritAc and TA-G differed only quantitatively. Metabolite concentrations were positively correlated within and between the different compound classes, indicating tight biosynthetic co-regulation. Latex metabolite extracts strongly repelled D. balteata larvae, suggesting that the latex constituents are biologically active.

  5. Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1.

    PubMed

    Lee, Jong Suk; Kim, Yong-Sook; Park, Sooyeon; Kim, Jihoon; Kang, So-Jung; Lee, Mi-Hwa; Ryu, Sangryeol; Choi, Jong Myoung; Oh, Tae-Kwang; Yoon, Jung-Hoon

    2011-07-01

    A Gram-negative, red-pigment-producing marine bacterial strain, designated S1-1, was isolated from the tidal flat sediment of the Yellow Sea, Korea. On the basis of phenotypic, phylogenetic, and genetic data, strain S1-1 (KCTC 11448BP) represented a new species of the genus Zooshikella. Thus, we propose the name Zooshikella rubidus sp. nov. Liquid chromatography and mass spectrometry of the red pigments produced by strain S1-1 revealed that the major metabolic compounds were prodigiosin and cycloprodigiosin. In addition, this organism produced six minor prodigiosin analogues, including two new structures that were previously unknown. To our knowledge, this is the first description of a microorganism that simultaneously produces prodigiosin and cycloprodigiosin as two major metabolites. Both prodigiosin and cycloprodigiosin showed antimicrobial activity against several microbial species. These bacteria were approximately 1.5-fold more sensitive to cycloprodigiosin than to prodigiosin. The metabolites also showed anticancer activity against human melanoma cells, which showed significantly more sensitivity to prodigiosin than to cycloprodigiosin. The secondary metabolite profiles of strain S1-1 and two reference bacterial strains were compared by liquid chromatography-mass spectrometry. Multivariate statistical analyses based on secondary metabolite profiles by liquid chromatography-mass spectrometry indicated that the metabolite profile of strain S1-1 could clearly be distinguished from those of two phylogenetically related, prodigiosin-producing bacterial strains.

  6. Exceptional Parent, 1993.

    ERIC Educational Resources Information Center

    Klein, Stanley D., Ed.

    1993-01-01

    This document consists of the nine issues of the journal "Exceptional Parent" published during 1993. This journal contains articles particularly aimed at parents of children with disabilities. Major articles published during this period are the following: "Annual Guide to Products and Services"; "Coping with Incontinence" (Katherine F. Jeter);…

  7. A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans

    PubMed Central

    Ngole-Jeme, Veronica M.; Ekosse, Georges-Ivo E.

    2015-01-01

    This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils. PMID:26264010

  8. A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans.

    PubMed

    Ngole-Jeme, Veronica M; Ekosse, Georges-Ivo E

    2015-08-01

    This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils. PMID:26264010

  9. A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans.

    PubMed

    Ngole-Jeme, Veronica M; Ekosse, Georges-Ivo E

    2015-07-31

    This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils.

  10. Amino Acid Variation in HLA Class II Proteins Is a Major Determinant of Humoral Response to Common Viruses

    PubMed Central

    Hammer, Christian; Begemann, Martin; McLaren, Paul J.; Bartha, István; Michel, Angelika; Klose, Beate; Schmitt, Corinna; Waterboer, Tim; Pawlita, Michael; Schulz, Thomas F.; Ehrenreich, Hannelore; Fellay, Jacques

    2015-01-01

    The magnitude of the human antibody response to viral antigens is highly variable. To explore the human genetic contribution to this variability, we performed genome-wide association studies of the immunoglobulin G response to 14 pathogenic viruses in 2,363 immunocompetent adults. Significant associations were observed in the major histocompatibility complex region on chromosome 6 for influenza A virus, Epstein-Barr virus, JC polyomavirus, and Merkel cell polyomavirus. Using local imputation and fine mapping, we identified specific amino acid residues in human leucocyte antigen (HLA) class II proteins as the most probable causal variants underlying these association signals. Common HLA-DRβ1 haplotypes showed virus-specific patterns of humoral-response regulation. We observed an overlap between variants affecting the humoral response to influenza A and EBV and variants previously associated with autoimmune diseases related to these viruses. The results of this study emphasize the central and pathogen-specific role of HLA class II variation in the modulation of humoral immune response to viral antigens in humans. PMID:26456283

  11. Autophagy Competes for a Common Phosphatidylethanolamine Pool with Major Cellular PE-Consuming Pathways in Saccharomyces cerevisiae

    PubMed Central

    Wilson-Zbinden, Caroline; dos Santos, Aline Xavier da Silveira; Stoffel-Studer, Ingrid; van der Vaart, Aniek; Hofmann, Kay; Reggiori, Fulvio; Riezman, Howard; Kraft, Claudine; Peter, Matthias

    2015-01-01

    Autophagy is a highly regulated pathway that selectively degrades cellular constituents such as protein aggregates and excessive or damaged organelles. This transport route is characterized by engulfment of the targeted cargo by autophagosomes. The formation of these double-membrane vesicles requires the covalent conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine (PE). However, the origin of PE and the regulation of lipid flux required for autophagy remain poorly understood. Using a genetic screen, we found that the temperature-sensitive growth and intracellular membrane organization defects of mcd4-174 and mcd4-P301L mutants are suppressed by deletion of essential autophagy genes such as ATG1 or ATG7. MCD4 encodes an ethanolamine phosphate transferase that uses PE as a precursor for an essential step in the synthesis of the glycosylphosphatidylinositol (GPI) anchor used to link a subset of plasma membrane proteins to lipid bilayers. Similar to the deletion of CHO2, a gene encoding the enzyme converting PE to phosphatidylcholine (PC), deletion of ATG7 was able to restore lipidation and plasma membrane localization of the GPI-anchored protein Gas1 and normal organization of intracellular membranes. Conversely, overexpression of Cho2 was lethal in mcd4-174 cells grown at restrictive temperature. Quantitative lipid analysis revealed that PE levels are substantially reduced in the mcd4-174 mutant but can be restored by deletion of ATG7 or CHO2. Taken together, these data suggest that autophagy competes for a common PE pool with major cellular PE-consuming pathways such as the GPI anchor and PC synthesis, highlighting the possible interplay between these pathways and the existence of signals that may coordinate PE flux. PMID:25519895

  12. Bacterial are the major contributors to the macrophage stimulating activity exhibited by extracts of common edible mushrooms

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Background: Recent studies have indicated that a major contributor to the innate immune enhancing properties of some medicinal plants is derived from the cell wall components of bacteria colonizing these plants. Purpose: The purpose of the current study was to assess if the bacteria present withi...

  13. Transdiagnostic commonalities and differences in resting state functional connectivity of the default mode network in schizophrenia and major depression.

    PubMed

    Schilbach, L; Hoffstaedter, F; Müller, V; Cieslik, E C; Goya-Maldonado, R; Trost, S; Sorg, C; Riedl, V; Jardri, R; Sommer, I; Kogler, L; Derntl, B; Gruber, O; Eickhoff, S B

    2016-01-01

    Schizophrenia and depression are prevalent psychiatric disorders, but their underlying neural bases remains poorly understood. Neuroimaging evidence has pointed towards the relevance of functional connectivity aberrations in default mode network (DMN) hubs, dorso-medial prefrontal cortex and precuneus, in both disorders, but commonalities and differences in resting state functional connectivity of those two regions across disorders has not been formally assessed. Here, we took a transdiagnostic approach to investigate resting state functional connectivity of those two regions in 75 patients with schizophrenia and 82 controls from 4 scanning sites and 102 patients with depression and 106 controls from 3 sites. Our results demonstrate common dysconnectivity patterns as indexed by a significant reduction of functional connectivity between precuneus and bilateral superior parietal lobe in schizophrenia and depression. Furthermore, our findings highlight diagnosis-specific connectivity reductions of the parietal operculum in schizophrenia relative to depression. In light of evidence that points towards the importance of the DMN for social cognitive abilities and well documented impairments of social interaction in both patient groups, it is conceivable that the observed transdiagnostic connectivity alterations may contribute to interpersonal difficulties, but this could not be assessed directly in our study as measures of social behavior were not available. Given the operculum's role in somatosensory integration, diagnosis-specific connectivity reductions may indicate a pathophysiological mechanism for basic self-disturbances that is characteristic of schizophrenia, but not depression. PMID:26904405

  14. Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis.

    PubMed

    Rao, Shuquan; Yao, Yao; Ryan, Joanne; Li, Tao; Wang, Duan; Zheng, Chuan; Xu, Yong; Xu, Qi

    2016-01-01

    Previous studies have investigated the association between common variants in FKBP5 and MDD; however, the results remain inconsistent. In order to conduct a comprehensive meta-analysis of the association between FKBP5 variants and MDD risk, seven studies involving 26582 subjects, including 12491 cases with MDD and 14091 controls, were enrolled totally. Four common SNPs (rs1360780, rs4713916, rs3800373 and rs755658) with complete data from two or more studies were analyzed. In the total sample, there was no evidence of a significant association between MDD and any of the four SNPs using a random-effects model. However, after removing one heterogeneous German study, as indicated by sensitivity analysis, both the rs1360780 T-allele (Z = 2.95, P = 0.003, OR = 1.06, 95% CI = 1.02-1.11) and the rs3800373 C-allele (Z = 3.05, P = 0.002, OR = 1.07, 95% CI 1.02-1.12) were significantly associated with MDD in a fixed-effect model. Our study thus provides support for an association between specific FKBP5 genetic variants and MDD risk. Rs4713916 was not significantly associated with MDD; However, this analysis had limited statistical power and larger sample sizes are required to further validate this result. Future research should also investigate possible gender- and ethnicity-specific differences in the association between FKBP5 and MDD. PMID:27601205

  15. Transdiagnostic commonalities and differences in resting state functional connectivity of the default mode network in schizophrenia and major depression.

    PubMed

    Schilbach, L; Hoffstaedter, F; Müller, V; Cieslik, E C; Goya-Maldonado, R; Trost, S; Sorg, C; Riedl, V; Jardri, R; Sommer, I; Kogler, L; Derntl, B; Gruber, O; Eickhoff, S B

    2016-01-01

    Schizophrenia and depression are prevalent psychiatric disorders, but their underlying neural bases remains poorly understood. Neuroimaging evidence has pointed towards the relevance of functional connectivity aberrations in default mode network (DMN) hubs, dorso-medial prefrontal cortex and precuneus, in both disorders, but commonalities and differences in resting state functional connectivity of those two regions across disorders has not been formally assessed. Here, we took a transdiagnostic approach to investigate resting state functional connectivity of those two regions in 75 patients with schizophrenia and 82 controls from 4 scanning sites and 102 patients with depression and 106 controls from 3 sites. Our results demonstrate common dysconnectivity patterns as indexed by a significant reduction of functional connectivity between precuneus and bilateral superior parietal lobe in schizophrenia and depression. Furthermore, our findings highlight diagnosis-specific connectivity reductions of the parietal operculum in schizophrenia relative to depression. In light of evidence that points towards the importance of the DMN for social cognitive abilities and well documented impairments of social interaction in both patient groups, it is conceivable that the observed transdiagnostic connectivity alterations may contribute to interpersonal difficulties, but this could not be assessed directly in our study as measures of social behavior were not available. Given the operculum's role in somatosensory integration, diagnosis-specific connectivity reductions may indicate a pathophysiological mechanism for basic self-disturbances that is characteristic of schizophrenia, but not depression.

  16. Transdiagnostic commonalities and differences in resting state functional connectivity of the default mode network in schizophrenia and major depression

    PubMed Central

    Schilbach, L.; Hoffstaedter, F.; Müller, V.; Cieslik, E.C.; Goya-Maldonado, R.; Trost, S.; Sorg, C.; Riedl, V.; Jardri, R.; Sommer, I.; Kogler, L.; Derntl, B.; Gruber, O.; Eickhoff, S.B.

    2015-01-01

    Schizophrenia and depression are prevalent psychiatric disorders, but their underlying neural bases remains poorly understood. Neuroimaging evidence has pointed towards the relevance of functional connectivity aberrations in default mode network (DMN) hubs, dorso-medial prefrontal cortex and precuneus, in both disorders, but commonalities and differences in resting state functional connectivity of those two regions across disorders has not been formally assessed. Here, we took a transdiagnostic approach to investigate resting state functional connectivity of those two regions in 75 patients with schizophrenia and 82 controls from 4 scanning sites and 102 patients with depression and 106 controls from 3 sites. Our results demonstrate common dysconnectivity patterns as indexed by a significant reduction of functional connectivity between precuneus and bilateral superior parietal lobe in schizophrenia and depression. Furthermore, our findings highlight diagnosis-specific connectivity reductions of the parietal operculum in schizophrenia relative to depression. In light of evidence that points towards the importance of the DMN for social cognitive abilities and well documented impairments of social interaction in both patient groups, it is conceivable that the observed transdiagnostic connectivity alterations may contribute to interpersonal difficulties, but this could not be assessed directly in our study as measures of social behavior were not available. Given the operculum's role in somatosensory integration, diagnosis-specific connectivity reductions may indicate a pathophysiological mechanism for basic self-disturbances that is characteristic of schizophrenia, but not depression. PMID:26904405

  17. Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis

    NASA Astrophysics Data System (ADS)

    Rao, Shuquan; Yao, Yao; Ryan, Joanne; Li, Tao; Wang, Duan; Zheng, Chuan; Xu, Yong; Xu, Qi

    2016-09-01

    Previous studies have investigated the association between common variants in FKBP5 and MDD; however, the results remain inconsistent. In order to conduct a comprehensive meta-analysis of the association between FKBP5 variants and MDD risk, seven studies involving 26582 subjects, including 12491 cases with MDD and 14091 controls, were enrolled totally. Four common SNPs (rs1360780, rs4713916, rs3800373 and rs755658) with complete data from two or more studies were analyzed. In the total sample, there was no evidence of a significant association between MDD and any of the four SNPs using a random-effects model. However, after removing one heterogeneous German study, as indicated by sensitivity analysis, both the rs1360780 T-allele (Z = 2.95, P = 0.003, OR = 1.06, 95% CI = 1.02–1.11) and the rs3800373 C-allele (Z = 3.05, P = 0.002, OR = 1.07, 95% CI 1.02–1.12) were significantly associated with MDD in a fixed-effect model. Our study thus provides support for an association between specific FKBP5 genetic variants and MDD risk. Rs4713916 was not significantly associated with MDD; However, this analysis had limited statistical power and larger sample sizes are required to further validate this result. Future research should also investigate possible gender- and ethnicity-specific differences in the association between FKBP5 and MDD.

  18. Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis

    PubMed Central

    Rao, Shuquan; Yao, Yao; Ryan, Joanne; Li, Tao; Wang, Duan; Zheng, Chuan; Xu, Yong; Xu, Qi

    2016-01-01

    Previous studies have investigated the association between common variants in FKBP5 and MDD; however, the results remain inconsistent. In order to conduct a comprehensive meta-analysis of the association between FKBP5 variants and MDD risk, seven studies involving 26582 subjects, including 12491 cases with MDD and 14091 controls, were enrolled totally. Four common SNPs (rs1360780, rs4713916, rs3800373 and rs755658) with complete data from two or more studies were analyzed. In the total sample, there was no evidence of a significant association between MDD and any of the four SNPs using a random-effects model. However, after removing one heterogeneous German study, as indicated by sensitivity analysis, both the rs1360780 T-allele (Z = 2.95, P = 0.003, OR = 1.06, 95% CI = 1.02–1.11) and the rs3800373 C-allele (Z = 3.05, P = 0.002, OR = 1.07, 95% CI 1.02–1.12) were significantly associated with MDD in a fixed-effect model. Our study thus provides support for an association between specific FKBP5 genetic variants and MDD risk. Rs4713916 was not significantly associated with MDD; However, this analysis had limited statistical power and larger sample sizes are required to further validate this result. Future research should also investigate possible gender- and ethnicity-specific differences in the association between FKBP5 and MDD. PMID:27601205

  19. Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study.

    PubMed

    Marioni, Riccardo E; Batty, G David; Hayward, Caroline; Kerr, Shona M; Campbell, Archie; Hocking, Lynne J; Porteous, David J; Visscher, Peter M; Deary, Ian J

    2014-03-01

    Greater height and higher intelligence test scores are predictors of better health outcomes. Here, we used molecular (single-nucleotide polymorphism) data to estimate the genetic correlation between height and general intelligence (g) in 6,815 unrelated subjects (median age 57, IQR 49-63) from the Generation Scotland: Scottish Family Health Study cohort. The phenotypic correlation between height and g was 0.16 (SE 0.01). The genetic correlation between height and g was 0.28 (SE 0.09) with a bivariate heritability estimate of 0.71. Understanding the molecular basis of the correlation between height and intelligence may help explain any shared role in determining health outcomes. This study identified a modest genetic correlation between height and intelligence with the majority of the phenotypic correlation being explained by shared genetic influences.

  20. SYNE1 ataxia is a common recessive ataxia with major non-cerebellar features: a large multi-centre study.

    PubMed

    Synofzik, Matthis; Smets, Katrien; Mallaret, Martial; Di Bella, Daniela; Gallenmüller, Constanze; Baets, Jonathan; Schulze, Martin; Magri, Stefania; Sarto, Elisa; Mustafa, Mona; Deconinck, Tine; Haack, Tobias; Züchner, Stephan; Gonzalez, Michael; Timmann, Dagmar; Stendel, Claudia; Klopstock, Thomas; Durr, Alexandra; Tranchant, Christine; Sturm, Marc; Hamza, Wahiba; Nanetti, Lorenzo; Mariotti, Caterina; Koenig, Michel; Schöls, Ludger; Schüle, Rebecca; de Jonghe, Peter; Anheim, Mathieu; Taroni, Franco; Bauer, Peter

    2016-05-01

    , including premature death due to respiratory dysfunction. With a relative frequency of ∼5%, SYNE1 is one of the more common recessive ataxias worldwide.

  1. SYNE1 ataxia is a common recessive ataxia with major non-cerebellar features: a large multi-centre study.

    PubMed

    Synofzik, Matthis; Smets, Katrien; Mallaret, Martial; Di Bella, Daniela; Gallenmüller, Constanze; Baets, Jonathan; Schulze, Martin; Magri, Stefania; Sarto, Elisa; Mustafa, Mona; Deconinck, Tine; Haack, Tobias; Züchner, Stephan; Gonzalez, Michael; Timmann, Dagmar; Stendel, Claudia; Klopstock, Thomas; Durr, Alexandra; Tranchant, Christine; Sturm, Marc; Hamza, Wahiba; Nanetti, Lorenzo; Mariotti, Caterina; Koenig, Michel; Schöls, Ludger; Schüle, Rebecca; de Jonghe, Peter; Anheim, Mathieu; Taroni, Franco; Bauer, Peter

    2016-05-01

    , including premature death due to respiratory dysfunction. With a relative frequency of ∼5%, SYNE1 is one of the more common recessive ataxias worldwide. PMID:27086870

  2. Heterogeneity in the prognosis of major depression: from the common cold to a highly debilitating and recurrent illness.

    PubMed

    Lorenzo-Luaces, L

    2015-12-01

    Two different and seemingly competing views on the diagnosis of major depressive disorder (MDD) exist. The first is that the diagnosis conflates adaptive sadness reactions with pathological states of depressed mood and that MDD is overdiagnosed and overtreated. The second is that MDD is an underdiagnosed and undertreated disorder, and one that is best characterised by a severe, chronic, recurrent or treatment-resistant course. Existing research suggests that both views are valid and merit being integrated. Anywhere from 30 to 50% of individuals will meet criteria for MDD at some point in their life. About half of these episodes are of brief duration and unlikely to recur. However, a remaining half is either chronic or recurrent. Data on the outpatient diagnosis of depression support the view that depression is simultaneously underdiagnosed and undertreated as well as overdiagnosed and overtreated. About one-third of the patients who meet criteria for MDD and receive placebos experience clinically significant and long-lasting improvement. Many other patients, however, are unresponsive to one or multiple active treatments. Thus, the diagnosis of MDD likely applies to individuals who are experiencing either normal periods of sadness or single-episode afflictions that are mild, unlikely to recur, and are placebo responsive, as well as to individuals with more severe clinical profiles. More research is needed that can help ascertain what contextual or biopsychological variables help distinguish between individuals who may be experiencing adaptive states of negative affect and those who experience severe, chronic, recurrent or treatment-resistant depressions. PMID:26081748

  3. Feeling like a group after a natural disaster: Common ingroup identity and relations with outgroup victims among majority and minority young children.

    PubMed

    Vezzali, Loris; Cadamuro, Alessia; Versari, Annalisa; Giovannini, Dino; Trifiletti, Elena

    2015-09-01

    We conducted a field study to test whether the common ingroup identity model (Gaertner & Dovidio, 2000, reducing intergroup bias: The common ingroup identity model. Philadelphia, PA: Psychology Press) could be a useful tool to improve intergroup relations in the aftermath of a natural disaster. Participants were majority (Italian) and minority (immigrant) elementary school children (N = 517) living in the area struck by powerful earthquakes in May 2012. Results revealed that, among majority children, the perceived external threat represented by the earthquake was associated with greater perceptions of belonging to a common ingroup including both ingroup and outgroup. In turn, heightened one-group perceptions were associated with greater willingness to meet and help outgroup victims, both directly and indirectly via more positive outgroup attitudes. Among immigrant children, perceived disaster threat was not associated with any of the dependent variables; one-group perceptions were positively associated with outgroup attitudes, helping and contact intentions towards outgroup victims. Thus, one-group perceptions after a natural disaster may promote more positive and supporting relations between the majority and the minority group. We discuss the theoretical and practical implications of the findings. PMID:25330995

  4. Feeling like a group after a natural disaster: Common ingroup identity and relations with outgroup victims among majority and minority young children.

    PubMed

    Vezzali, Loris; Cadamuro, Alessia; Versari, Annalisa; Giovannini, Dino; Trifiletti, Elena

    2015-09-01

    We conducted a field study to test whether the common ingroup identity model (Gaertner & Dovidio, 2000, reducing intergroup bias: The common ingroup identity model. Philadelphia, PA: Psychology Press) could be a useful tool to improve intergroup relations in the aftermath of a natural disaster. Participants were majority (Italian) and minority (immigrant) elementary school children (N = 517) living in the area struck by powerful earthquakes in May 2012. Results revealed that, among majority children, the perceived external threat represented by the earthquake was associated with greater perceptions of belonging to a common ingroup including both ingroup and outgroup. In turn, heightened one-group perceptions were associated with greater willingness to meet and help outgroup victims, both directly and indirectly via more positive outgroup attitudes. Among immigrant children, perceived disaster threat was not associated with any of the dependent variables; one-group perceptions were positively associated with outgroup attitudes, helping and contact intentions towards outgroup victims. Thus, one-group perceptions after a natural disaster may promote more positive and supporting relations between the majority and the minority group. We discuss the theoretical and practical implications of the findings.

  5. Exceptional Responders Initial Feasibility Results

    Cancer.gov

    A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical

  6. Evidence for phosphorylation of the major seed storage protein of the common bean and its phosphorylation-dependent degradation during germination.

    PubMed

    López-Pedrouso, María; Alonso, Jana; Zapata, Carlos

    2014-03-01

    Phaseolin is the major seed storage protein of common bean, Phaseolus vulgaris L., accounting for up to 50 % of the total seed proteome. The regulatory mechanisms responsible for the synthesis, accumulation and degradation of phaseolin in the common bean seed are not yet sufficiently known. Here, we report on a systematic study in dormant and 4-day germinating bean seeds from cultivars Sanilac (S) and Tendergreen (T) to explore the presence and dynamics of phosphorylated phaseolin isoforms. High-resolution two-dimensional electrophoresis in combination with the phosphoprotein-specific Pro-Q Diamond phosphoprotein fluorescent stain and chemical dephosphorylation by hydrogen fluoride-pyridine enabled us to identify differentially phosphorylated phaseolin polypeptides in dormant and germinating seeds from cultivars S and T. Phosphorylated forms of the two subunits of type α and β that compose the phaseolin were identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) and MALDI-TOF/TOF tandem MS. In addition, we found that the levels of phosphorylation of the phaseolin changed remarkably in the seed transition from dormancy to early germination stage. Temporal changes in the extent of phosphorylation in response to physiological and metabolic variations suggest that phosphorylated phaseolin isoforms have functional significance. In particular, this prospective study supports the hypothesis that mobilization of the phaseolin in germinating seeds occurs through the degradation of highly phosphorylated isoforms. Taken together, our results indicate that post-translational phaseolin modifications through phosphorylations need to be taken into consideration for a better understanding of the molecular mechanisms underlying its regulation.

  7. From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms.

    PubMed

    Cammen, Kristina M; Wilcox, Lynsey A; Rosel, Patricia E; Wells, Randall S; Read, Andrew J

    2015-02-01

    The role the major histocompatibility complex (MHC) plays in response to exposure to environmental toxins is relatively poorly understood, particularly in comparison to its well-described role in pathogen immunity. We investigated associations between MHC diversity and resistance to brevetoxins in common bottlenose dolphins (Tursiops truncatus). A previous genome-wide association study investigating an apparent difference in harmful algal bloom (HAB) resistance among dolphin populations in the Gulf of Mexico identified genetic variation associated with survival in close genomic proximity to multiple MHC class II loci. Here, we characterized genetic variation at DQA, DQB, DRA, and DRB loci in dolphins from central-west Florida and the Florida Panhandle, including dolphins that died during HABs and dolphins presumed to have survived HAB exposure. We found that DRB and DQB exhibited patterns of genetic differentiation among geographic regions that differed from neutral microsatellite loci. In addition, genetic differentiation at DRB across multiple pairwise comparisons of live and dead dolphins was greater than differentiation observed at neutral loci. Our findings at these MHC loci did not approach the strength of association with survival previously described for a nearby genetic variant. However, the results provide evidence that selective pressures at the MHC vary among dolphin populations that differ in the frequency of HAB exposure and that the overall composition of DRB variants differs between dolphin survivors and non-survivors of HABs. These results may suggest a potential role of MHC diversity in variable survival of bottlenose dolphins exposed to HABs.

  8. Exceptional Science Teaching

    NASA Astrophysics Data System (ADS)

    Lustick, David

    2011-04-01

    What kind of teaching is indicative of an exceptional practice? In this secondary science teacher workshop, participants will explore and consider an array of standards based instructional strategies designed to foster specific types of student learning outcomes. Using a backward design approach, first the goals of science learning will be identified and then the best strategies for achieving those goals will be described. Finally, policies and practices that promote (or stifle) exceptional science teaching will be discussed. Specific examples of classroom teaching will be shared throughout to illustrate the concepts addressed.

  9. Exceptional Parent, 1996.

    ERIC Educational Resources Information Center

    Klein, Stanley, Ed.

    1996-01-01

    Twelve 1996 issues of "Exceptional Parent" magazine provide a variety of articles and resources on parenting the child or young adult with a disability. The January issue is a resource guide, with directories of national organizations, associations, products, and services. The February issue focuses on early childhood, including articles on…

  10. Exceptional Parent, 2001.

    ERIC Educational Resources Information Center

    Rader, Rick, Ed.

    2001-01-01

    This document collects the 12 monthly issues of Volume 31 of "Exceptional Parent," a magazine focused on practical advice for parents of children with disabilities. Most of the issues include a focus topic as well as articles on other issues, columns, reviews, and letters. These 12 issues concentrate on the following areas: (1) information…

  11. Grading Exceptional Learners

    ERIC Educational Resources Information Center

    Jung, Lee Ann; Guskey, Thomas R.

    2010-01-01

    Teachers often grapple with the challenge of giving report card grades to students with learning disabilities and English language learners. The authors offer a five-step model that "offers a fair, accurate, and legal way to adapt the grading process for exceptional learners." The model begins with a high-quality reporting system for all students…

  12. Exceptional Parent, 1995.

    ERIC Educational Resources Information Center

    Klein, Stanley, Ed.

    1995-01-01

    Twelve issues of "Exceptional Parent" magazine provide a variety of articles and resources on parenting the child or young adult with a disability. The January issue is a resource guide with directories of national organizations, associations, products, and services. The February issue focuses on early childhood, including assessment, day care,…

  13. Nothing Exceptional: Against Agamben

    ERIC Educational Resources Information Center

    Colatrella, Steven

    2011-01-01

    Giorgio Agamben's work has become widely influential as a guide to explaining the extra-constitutional powers assumed by governments under the rubric of the War on Terror. His formulations, such as Homo Sacer and State of Exception, have been extended to apply to a wide variety of experiences of repression of liberties or social control, including…

  14. Giftedness: an exceptionality examined.

    PubMed

    Robinson, A; Clinkenbeard, P R

    1998-01-01

    The study of giftedness has practical origins. High-level performance intrigues people. Theoretically, the study of giftedness is related to the psychology of individual differences and has focused on the constructs of intelligence, creativity, and motivation. At a practical level, the research is largely related to school and family contexts, which develop gifts and talents in children and youth. Although broadened definitions of giftedness have emerged, the most extensive body of research available for review concentrates on intellectual giftedness. The varying definitions of giftedness and the impact of social context and diversity on the development of talent pose significant challenges for the field. Finally, the study of exceptionally advanced performance provides insight into basic psychological processes and the school contexts that develop talents in children and youth.

  15. Counseling Exceptional People.

    ERIC Educational Resources Information Center

    Benjamin, Libby; Walz, Garry R.

    This guide offers counselors and special education and classroom teachers assistance in counseling handicapped children. Major articles focus on counseling children who are mentally retarded, emotionally, visually and hearing impaired, learning disabled, and gifted. Additional information is provided on: (1) sexual fulfillment for the handicapped;…

  16. The major nucleoside triphosphatase in pea (Pisum sativum L.) nuclei and in rat liver nuclei share common epitopes also present in nuclear lamins

    NASA Technical Reports Server (NTRS)

    Tong, C. G.; Dauwalder, M.; Clawson, G. A.; Hatem, C. L.; Roux, S. J.

    1993-01-01

    The major nucleoside triphosphatase (NTPase) activities in mammalian and pea (Pisum sativum L.) nuclei are associated with enzymes that are very similar both biochemically and immunochemically. The major NTPase from rat liver nuclei appears to be a 46-kD enzyme that represents the N-terminal portion of lamins A and C, two lamina proteins that apparently arise from the same gene by alternate splicing. Monoclonal antibody (MAb) G2, raised to human lamin C, both immunoprecipitates the major (47 kD) NTPase in pea nuclei and recognizes it in western blot analyses. A polyclonal antibody preparation raised to the 47-kD pea NTPase (pc480) reacts with the same lamin bands that are recognized by MAb G2 in mammalian nuclei. The pc480 antibodies also bind to the same lamin-like bands in pea nuclear envelope-matrix preparations that are recognized by G2 and three other MAbs known to bind to mammalian lamins. In immunofluorescence assays, pc480 and anti-lamin antibodies stain both cytoplasmic and nuclear antigens in plant cells, with slightly enhanced staining along the periphery of the nuclei. These results indicate that the pea and rat liver NTPases are structurally similar and that, in pea nuclei as in rat liver nuclei, the major NTPase is probably derived from a lamin precursor by proteolysis.

  17. Discovery of A New Retrograde Trans-Neptunian Object: Hint of A Common Orbital Plane for Low Semi-Major Axis, High Inclination TNOs and Centaurs

    NASA Astrophysics Data System (ADS)

    Chen, Ying-Tung; Lin, Hsing-Wen; Holman, Matthew J.; Payne, Matthew John; Fraser, Wesley Cristopher; Lacerda, Pedro; Ip, Wing-Huen; Pan-STARRS 1 Builders

    2016-10-01

    The origin of high inclination objects beyond Jupiter, including trans-Neptunian objects (TNOs) and Centaurs, remains uncertain. We report the discovery of a retrograde TNO, which we nickname "Niku", detected by the Pan-STARRS 1 Outer Solar System Survey. The numerical integrations show that the orbital dynamics of Niku are very similar to those of 2008 KV42 (Drac), with a half-life of ~ 500 Myr and analogous orbital evolution. Comparing similar high inclination members announced by the Minor-Planet Center (q > 10 AU, a < 100 AU and i > 60), we find these objects exhibit a surprising clustering of ascending node, populating a common orbital plane. The statistical significance of 3.8-sigma suggests it is unlikely to be coincidental. An unknown mechanism is required to explain the observed clustering. This discovery may provide a pathway to investigating a possible reservoir of high-inclination objects.

  18. Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins.

    PubMed

    Liao, Dengqun; Pajak, Agnieszka; Karcz, Steven R; Chapman, B Patrick; Sharpe, Andrew G; Austin, Ryan S; Datla, Raju; Dhaubhadel, Sangeeta; Marsolais, Frédéric

    2012-10-01

    The lack of phaseolin and phytohaemagglutinin in common bean (dry bean, Phaseolus vulgaris) is associated with an increase in total cysteine and methionine concentrations by 70% and 10%, respectively, mainly at the expense of an abundant non-protein amino acid, S-methyl-cysteine. Transcripts were profiled between two genetically related lines differing for this trait at four stages of seed development using a high density microarray designed for common bean. Transcripts of multiple sulphur-rich proteins were elevated, several previously identified by proteomics, including legumin, basic 7S globulin, albumin-2, defensin, albumin-1, the Bowman-Birk type proteinase inhibitor, the double-headed trypsin inhibitor, and the Kunitz trypsin inhibitor. A co-ordinated regulation of transcripts coding for sulphate transporters, sulphate assimilatory enzymes, serine acetyltransferases, cystathionine β-lyase, homocysteine S-methyltransferase and methionine gamma-lyase was associated with changes in cysteine and methionine concentrations. Differential gene expression of sulphur-rich proteins preceded that of sulphur metabolic enzymes, suggesting a regulation by demand from the protein sink. Up-regulation of SERAT1;1 and -1;2 expression revealed an activation of cytosolic O-acetylserine biosynthesis. Down-regulation of SERAT2;1 suggested that cysteine and S-methyl-cysteine biosynthesis may be spatially separated in different subcellular compartments. Analysis of free amino acid profiles indicated that enhanced cysteine biosynthesis was correlated with a depletion of O-acetylserine. These results contribute to our understanding of the regulation of sulphur metabolism in developing seed in response to a change in the composition of endogenous proteins. PMID:23066144

  19. Students' Strategies for Exception Handling

    ERIC Educational Resources Information Center

    Rashkovits, Rami; Lavy, Ilana

    2011-01-01

    This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

  20. The X-Factor: an evaluation of common methods used to analyse major inter-segment kinematics during the golf swing.

    PubMed

    Brown, Susan J; Selbie, W Scott; Wallace, Eric S

    2013-01-01

    A common biomechanical feature of a golf swing, described in various ways in the literature, is the interaction between the thorax and pelvis, often termed the X-Factor. There is no consistent method used within golf biomechanics literature however to calculate these segment interactions. The purpose of this study was to examine X-factor data calculated using three reported methods in order to determine the similarity or otherwise of the data calculated using each method. A twelve-camera three-dimensional motion capture system was used to capture the driver swings of 19 participants and a subject specific three-dimensional biomechanical model was created with the position and orientation of each model estimated using a global optimisation algorithm. Comparison of the X-Factor methods showed significant differences for events during the swing (P < 0.05). Data for each kinematic measure were derived as a times series for all three methods and regression analysis of these data showed that whilst one method could be successfully mapped to another, the mappings between methods are subject dependent (P <0.05). Findings suggest that a consistent methodology considering the X-Factor from a joint angle approach is most insightful in describing a golf swing. PMID:23463985

  1. Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb-Drug Interactions

    PubMed Central

    Awortwe, Charles; Bouic, Patrick J.; Masimirembwa, Collen M.; Rosenkranz, Bernd

    2015-01-01

    The purpose of this study was to evaluate the potential risk of common herbal medicines used by HIV-infected patients in Africa for herb-drug interactions (HDI). High throughput screening assays consisting of recombinant Cytochrome P450 enzymes (CYPs) and fluorescent probes, and parallel artificial membrane permeability assays (PAMPA) were used. The potential of herbal medicines to cause HDI was ranked according to FDA guidelines for reversible inhibition and categorization of time dependent inhibition was based on the normalized ratio. CYPs 1A2 and 3A4 were most inhibited by the herbal extracts. H. hemerocallidea (IC50 = 0.63 μg/mL and 58 μg/mL) and E. purpurea (IC50 = 20 μg/mL and 12 μg/mL) were the potent inhibitors of CYPs 1A2 and 3A4 respectively. L. frutescens and H. hemerocallidea showed clear time dependent inhibition on CYP3A4. Furthermore, the inhibitory effect of both H. hemerocallidea and L. frutescens before and after PAMPA were identical. The results indicate potential HDI of H. hemerocallidea, L. frutescens and E. purpurea with substrates of the affected enzymes if maximum in vivo concentration is achieved. PMID:24475926

  2. Mapping of major diseases and devising prevention and control regimen to common diseases in cattle and shoats in Dassenech district of South Omo Zone, South-Western Ethiopia.

    PubMed

    Molla, Bereket; Delil, Faris

    2015-01-01

    Livestock production system, particularly in pastoral areas, is mainly constrained by rampant livestock diseases and seasonal feed and water shortages. In areas like Dassenech, bordering Kenya and South Sudan, this risks are pronounced due to the unavailability of appropriate prevention and control. The research was conducted with the objectives of identifying major rampant diseases and designing appropriate prevention and control strategies. A cross-sectional study was employed, conducted using both participatory epidemiology and conventional veterinary investigation. Spatial and temporal occurrence of diseases was assessed. The major five diseases in bovine were contagious bovine pleuro pneumonia (CBPP), septicemic pasteurellosis, anthrax, foot and mouth disease (FMD), and black leg, in that order of importance. Similarly, in ovine, "unknown recent disease," pneumonic pasteurellosis, brucellosis, peste des petits ruminants (PPR), and septicemic pasteurellosis were ranked, starting from the most important whereas in caprine PPR, contagious caprine pleuro pneumonia (CCPP), goat pox, brucellosis, and pneumonic pasteurellosis were ranked in that order of importance. The seroprevalence in bovine were found to be 97, 10, 18, and 15% for septicemic pasteurelosis, CBPP, FMD, and brucellosis, respectively. The seroprevalence of septicemic pasteurelosis, PPR, and brucellosis was 86, 49, and 3%, respectively, in ovine. The seroprevalence of caprine sera for CCPP, PPR, and brucellosis were 87, 42, and 0%, respectively. The prevention and control regimen, vaccination against CBPP, should be at the beginning of wet season, whereas, for FMD, it should be at the end of wet season in bovine. Brucellosis for bovine, if has to be applied, should be at the beginning of dry season. PPR vaccination for ovine should be at the beginning of wet season whereas, for caprine, it should be just before start of dry season. Furthermore, the efficacy of aforementioned vaccines and its protocol

  3. Tryptophan–Kynurenine Metabolism as a Common Mediator of Genetic and Environmental Impacts in Major Depressive Disorder: The Serotonin Hypothesis Revisited 40 Years Later

    PubMed Central

    Oxenkrug, Gregory F.

    2011-01-01

    The original 1969 Lancet paper proposed, “in depression the activity of liver tryptophan-pyrrolase is stimulated by raised blood corticosteroids levels, and metabolism of tryptophan is shunted away from serotonin production, and towards kynurenine production.” Discovery of neurotropic activity of kynurenines suggested that up-regulation of the tryptophan-kynurenine pathway not only augmented serotonin deficiency but also underlined depression-associated anxiety, psychosis and cognitive decline. The present review of genetic and hormonal factors regulating kynurenine pathway of tryptophan metabolism suggests that this pathway mediates both genetic and environmental mechanisms of depression. Rate-limiting enzymes of kynurenine formation, tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are activated by stress hormones (TDO) and/or by pro-inflammatory cytokines (IDO). Simultaneous presence of high producers alleles of proinflammatory cytokines genes (e.g., interferon-gamma and tumor necrosis factor-alpha) determines the genetic predisposition to depression via up-regulation of IDO while impact of environmental stresses is mediated via hormonal activation of TDO. Tryptophan-kynurenine pathway represents a major meeting point of gene-environment interaction in depression and a new target for pharmacological intervention. PMID:20686200

  4. Hsp70 and small Hsps are the major heat shock protein members involved in midgut metamorphosis in the common cutworm, Spodoptera litura.

    PubMed

    Gu, J; Huang, L-X; Shen, Y; Huang, L-H; Feng, Q-L

    2012-10-01

    Heat shock proteins (Hsps) are important chaperones, which are involved in various signal pathways and regulate lots of physiological processes. Early research suggested that some Hsps are involved in insect development. However, few studies have been carried out to explore the roles of Hsps, especially in larval-pupal metamorphosis. In the present study, 49 Hsp unigenes were identified in the Spodoptera litura transcriptome and their mRNA expression profiles during midgut metamorphosis were examined using a tag-based digital gene expression system. The genes with the most different levels of expression were then cloned and their expression patterns in midguts from sixth instar larvae to pupae were analysed using real time quantitative PCR. The responses of these genes to juvenile hormone (JH) and 20-hydroxyecdysone (20E) were also studied. The results showed that the mRNA levels of 22 Hsp unigenes changed significantly during midgut metamorphosis. Amongst these 22 unigenes, hsp70, hsp20.4 and hsp20.8 were the most up-regulated members, and hsp15.9, hsp19.3 and hsp22.0 were the most down-regulated ones. Further studies showed that hsp70, hsp20.4 and hsp20.8 were remarkably up-regulated by JH. In addition, 20E slightly increased the mRNA levels of both hsp20.4 and hsp20.8. However, hsp15.9, hsp19.3 and hsp22.0 did not respond to either JH or 20E. These results indicate that Hsp70 and small Hsps (sHsps) are probably the major players in midgut metamorphosis in S. litura. The current findings provide valuable insights into the roles of the Hsp superfamily in insect metamorphosis.

  5. Exceptional Solar-System Objects

    NASA Astrophysics Data System (ADS)

    Zellner, Benjamin

    1990-12-01

    This is a target-of-opportunity proposal for HST observations to be executed if a previously unknown, truly exceptional solar-system object or phenomenon is discovered either in the normal course of HST work or by anyone, anywhere. Trails due to unknown moving objects will often appear on HST images made for other purposes. A short trail seen near the opposition point or at high ecliptic latitude could represent a major addition to our knowledge of the solar system. Thus we further propose that all short trials seen on HST images taken in favorable regions of the sky be given a quick analysis in the Observation Support System for their possible significance. If an unusual object is found we propose to: (1) Seek from the owner of data rights permission to proceed as may be appropriate; (2) Contact the Minor Planet Center for an evaluation of the significance of the discovery; and (3) For an object that appears to be of great significance where effective groundbased followup appears unlikely, request the HST schedule be replanned for followup images and physical studies using HST.

  6. Major depression.

    PubMed

    Bentley, Susan M; Pagalilauan, Genevieve L; Simpson, Scott A

    2014-09-01

    Major depression is a common, disabling condition seen frequently in primary care practices. Non-psychiatrist ambulatory providers are increasingly responsible for diagnosing, and primarily managing patients suffering from major depressive disorder (MDD). The goal of this review is to help primary care providers to understand the natural history of MDD, identify practical tools for screening, and a thoughtful approach to management. Clinically challenging topics like co-morbid conditions, treatment resistant depression and pharmacotherapy selection with consideration to side effects and medication interactions, are also covered.

  7. 75 FR 67408 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ....gpoaccess.gov/fr/ . A consolidated listing of all authorities as of June 30 is also published each year. The... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... excepted service as required by 5 CFR 213.103. FOR FURTHER INFORMATION CONTACT: Roland Edwards,...

  8. 76 FR 2929 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ....gpoaccess.gov/fr/ . A consolidated listing of all authorities as of June 30 is also published each year. The... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... excepted service as required by 5 CFR 213.103. FOR FURTHER INFORMATION CONTACT: Roland Edwards,...

  9. 75 FR 3947 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ....gpoaccess.gov/ fr/. A consolidated listing of all authorities as of June 30 is also published each year. The... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... excepted service as required by 5 CFR 213.103. FOR FURTHER INFORMATION CONTACT: Roland Edwards,...

  10. 76 FR 53157 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ... Federal Register at http://www.gpoaccess.gov/fr/ fr/. A consolidated listing of all authorities as of June... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... excepted service as required by 5 CFR 213.103. FOR FURTHER INFORMATION CONTACT: Roland Edwards,...

  11. A World of Exceptional Children.

    ERIC Educational Resources Information Center

    Conroy, Elizabeth H.; And Others

    This fifth chapter in "Elementary School Counseling in a Changing World" contains four journal articles which focus on exceptional children and helping elementary school counselors build a supportive learning environment for exceptional children. "Primary Prevention for Gifted Students: A Parent Education Group" by Elizabeth Conroy describes a…

  12. No Common Opinion on the Common Core

    ERIC Educational Resources Information Center

    Henderson, Michael B.; Peterson, Paul E.; West, Martin R.

    2015-01-01

    According to the three authors of this article, the 2014 "EdNext" poll yields four especially important new findings: (1) Opinion with respect to the Common Core has yet to coalesce. The idea of a common set of standards across the country has wide appeal, and the Common Core itself still commands the support of a majority of the public.…

  13. Gifted Students with Disabilities: "Twice Exceptionality" in the Music Classroom

    ERIC Educational Resources Information Center

    Abramo, Joseph Michael

    2015-01-01

    Many music educators teach students who are both gifted and possess a learning disability--what is commonly referred to as "twice exceptionality." This article describes some characteristics of twice-exceptional students, the challenges these students often face in school, and some strategies music educators can use to properly…

  14. Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease.

    PubMed Central

    Blander, S J; Horwitz, M A

    1993-01-01

    We have examined the capacity of the major cytoplasmic membrane protein (MCMP) of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, to induce protective immunity in a guinea pig model of Legionnaires' disease. We purified MCMP to homogeneity from L. pneumophila by buffer extraction, ion-exchange chromatography, and molecular sieve chromatography. Guinea pigs immunized with MCMP developed a strong cell-mediated immune response to the immunogen manifest by marked cutaneous delayed-type hypersensitivity. Guinea pigs immunized with MCMP and then challenged with a lethal aerosol dose of L. pneumophila exhibited a high level of protective immunity. Altogether, in four independent experiments, 55 of 64 (86%) animals immunized three times with 0.6-40 micrograms MCMP including 11 of 11 (100%) animals immunized three times with 40 micrograms MCMP survived aerosol challenge with L. pneumophila compared with 1 of 29 (3%) sham-immunized control animals (P < 0.0001, Cochran-Mantel-Haenszel X2 statistic for pooled data). To our knowledge, MCMP is the first member of the hsp 60 family of proteins shown to induce protective immunity to a microbial pathogen. MCMP has potential as a vaccine against Legionnaires' disease. Since MCMP is a genus common antigen, vaccination with a combination of MCMPs derived from different Legionella species has the potential of inducing protective immunity against all the major Legionella species causing human disease. Images PMID:8432872

  15. An exception to court rule

    SciTech Connect

    Black, B.; Strott, L.

    1995-01-01

    In August, 1994, the U.S. Court of Appeals for the 3rd Circuit handed down a decision that could make it much easier to challenge Superfund remedies in court. The Superfund law explicitly limits judicial review of removal or remedial actions. There are five exceptions to the above which are described in this paper.

  16. 77 FR 49029 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ..... Congressional and Deputy Director.... PM120017 6/26/2012 Legislative Affairs. Selective Service System... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... Resources Services, Executive Resources and Employee Development, Employee Services, 202-...

  17. Guidelines for Testing Exceptional Students.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. for Exceptional Children.

    The document provides information related to statewide testing of exceptional students for the North Carolina Annual, Minimum Skills Diagnostic, End-of-Course, and Competency Testing programs. Guidelines for the appropriate use of alternative test formats, aids, or a different test environment with disabled students are given. Included are rules…

  18. Grading Exceptional and Struggling Learners

    ERIC Educational Resources Information Center

    Jung, Lee Ann; Guskey, Thomas R.

    2011-01-01

    How can you ensure that you are grading your exceptional students fairly? Teachers receive very little guidance for grading students with disabilities, English learners, and those receiving services through a response-to-intervention (RTI) process. This practitioner-friendly book provides teachers and administrators with an effective framework for…

  19. 78 FR 71677 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This.../18/2013 Service. Assistant. Office of the Under Confidential DA130226 10/23/2013 Secretary Farm and Assistant. Foreign Agricultural Service. Office of the Director of the DA140001 10/30/2013 Secretary....

  20. 78 FR 47024 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... Executive Resources Services, Senior Executive Service and Performance Management, Employee Services, 202... Firearms (1) Criminal Investigator positions, grades GS-5 through GS-12 (or equivalent). Service under...

  1. 77 FR 32149 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... the Federal Register at www.gpoaccess.gov/fr/ . A consolidated listing of all authorities as of June... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This.... Deputy Under Confidential DD120020 1/5/2012 Secretary of Assistant. Defense (Logistics and...

  2. 78 FR 52580 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. ] SUMMARY...: Senior Executive Resources Services, Senior Executive Services and Performance Management, Employee... the U.S. Office of Personnel Management (OPM) publishes a notice of agency-specific...

  3. Learned Helplessness in Exceptional Children.

    ERIC Educational Resources Information Center

    Brock, Herman B.; Kowitz, Gerald T.

    The research literature on learned helplessness in exceptional children is reviewed and the authors' efforts to identify and retrain learning disabled (LD) children who have characteristics typical of learned helplessness are reported. Twenty-eight elementary aged LD children viewed as "learned helpless" were randomly assigned to one of four…

  4. Calendrical Savants: Exceptionality and Practice

    ERIC Educational Resources Information Center

    Cowan, Richard; Carney, Daniel P. J.

    2006-01-01

    The exceptionality of the skills of calendrical savants and the role of practice were investigated. Experiment 1 compared four autistic calendrical savants to Professor Conway, a distinguished mathematician with calendrical skills. Professor Conway answered questions over a greater range of years but some savants knew more calendrical…

  5. In search of exceptional responders.

    PubMed

    Poh, Alissa

    2015-01-01

    A new NCI initiative aims to accrue and molecularly profile as many as 300 cases of exceptional responses to cancer therapies, both targeted and standard. Researchers hope this exercise will yield new hypotheses to be tested in genomically driven clinical trials.

  6. 78 FR 28652 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... the Office of Personnel Management (OPM) publishes a notice of agency-specific authorities established... 3302; E.O. 10577, 3 CFR, 1954-1958 Comp., p. 218. U.S. Office of Personnel Management. Elaine...

  7. Career Futures for Exceptional Individuals.

    ERIC Educational Resources Information Center

    Kokaska, Charles J., Ed.

    The 33 selected papers from the National Topical Conference on Career Education for Exceptional Individuals are divided into six sections: career education (overview and future perspectives); programing and instruction; vocational assessment and training; counseling and career information; community involvement; and preparation of training…

  8. Common Cold

    MedlinePlus

    ... nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In ... avoid colds. There is no cure for the common cold. For relief, try Getting plenty of rest Drinking ...

  9. Symmetric spaces of exceptional groups

    SciTech Connect

    Boya, L. J.

    2010-02-15

    We address the problem of the reasons for the existence of 12 symmetric spaces with the exceptional Lie groups. The 1 + 2 cases for G{sub 2} and F{sub 4}, respectively, are easily explained from the octonionic nature of these groups. The 4 + 3 + 2 cases on the E{sub 6,7,8} series require the magic square of Freudenthal and, for the split case, an appeal to the supergravity chain in 5, 4, and 3 space-time dimensions.

  10. Exceptional geometry and Borcherds superalgebras

    NASA Astrophysics Data System (ADS)

    Palmkvist, Jakob

    2015-11-01

    We study generalized diffeomorphisms in exceptional geometry with U-duality group E n( n) from an algebraic point of view. By extending the Lie algebra {e}_n to an infinite-dimensional Borcherds superalgebra, involving also the extension to {e}_{n+1} , the generalized Lie derivatives can be expressed in a simple way, and the expressions take the same form for any n ≤ 7. The closure of the transformations then follows from the Jacobi identity and the grading of {e}_{n+1} with respect to {e}_n.

  11. Common Cold

    MedlinePlus

    ... News & Events Volunteer NIAID > Health & Research Topics > Common Cold Skip Website Tools Website Tools Print this page ... Help people who are suffering from the common cold by volunteering for NIAID clinical studies on ClinicalTrials. ...

  12. Chiral exceptional points in metasurfaces

    NASA Astrophysics Data System (ADS)

    Kang, Ming; Chen, Jing; Chong, Y. D.

    2016-09-01

    An exceptional point (EP) is a degeneracy occurring in a non-energy-conserving system, in which two eigenvectors of a non-Hermitian Hamiltonian coalesce. We explore how EPs can be realized in a metamaterial surface, or metasurface, consisting of a pair of lossy coupled linear antennas in each unit cell. EPs appear in the eigenvectors of the transmission matrix by tuning the frequency and the coupling and loss rates of the metasurface. Each EP is associated with the appearance of a circularly polarized transmission eigenstate; hence, within the parameter space of the system, the EPs lie along pairs of curves with distinct chirality. Our results are obtained using finite-difference time-domain simulations, as well as a fitted coupled-mode theory. The coupled-mode theory agrees well with the numerical results and is capable of accurately predicting the EP f curves.

  13. The Motivations of Exceptional Musicians

    ERIC Educational Resources Information Center

    Woody, Robert H.

    2004-01-01

    Music educators are interested in how students learn music performance skills. In this way, music teachers have something in common with certain music psychologists who study how musicians become expert performers. These researchers work with highly skilled musicians to learn what factors have contributed to their achievement in performance.…

  14. 42 CFR 423.578 - Exceptions process.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Exceptions process. 423.578 Section 423.578 Public..., Redeterminations, and Reconsiderations § 423.578 Exceptions process. (a) Requests for exceptions to a plan's tiered... sponsor may design its exception process so that very high cost or unique drugs are not eligible for...

  15. 42 CFR 423.578 - Exceptions process.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Exceptions process. 423.578 Section 423.578 Public... Determinations, Redeterminations, and Reconsiderations § 423.578 Exceptions process. (a) Requests for exceptions... sponsor may design its exception process so that very high cost or unique drugs are not eligible for...

  16. Clays, common

    USGS Publications Warehouse

    Virta, R.L.

    1998-01-01

    Part of a special section on the state of industrial minerals in 1997. The state of the common clay industry worldwide for 1997 is discussed. Sales of common clay in the U.S. increased from 26.2 Mt in 1996 to an estimated 26.5 Mt in 1997. The amount of common clay and shale used to produce structural clay products in 1997 was estimated at 13.8 Mt.

  17. Student Commons

    ERIC Educational Resources Information Center

    Gordon, Douglas

    2010-01-01

    Student commons are no longer simply congregation spaces for students with time on their hands. They are integral to providing a welcoming environment and effective learning space for students. Many student commons have been transformed into spaces for socialization, an environment for alternative teaching methods, a forum for large group meetings…

  18. A 2014 nationwide survey of the distribution of Soybean mosaic virus (SMV), Soybean yellow mottle mosaic virus (SYMMV) and Soybean yellow common mosaic virus (SYCMV) major viruses in South Korean soybean fields, and changes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 2014 symptomatic soybean samples were collected throughout Korea, and were tested for the most important soybean viruses found in Korea, namely Soybean mosaic virus (SMV), Soybean yellow common mosaic virus (SYCMV), and Soybean yellow mottle mosaic virus (SYMMV). SYMMV was most commonly detected,...

  19. Relaxation Training: A Promising Approach for Helping Exceptional Learners.

    ERIC Educational Resources Information Center

    Margolis, Howard

    1990-01-01

    This article describes common forms of relaxation training that can be used with at-risk or exceptional students in remedial, special education, or regular settings. In addition to reviewing salient research assessing the effects of relaxation training on reading achievement, attention, hyperactivity, impulsivity, self-concept, stress, and…

  20. 48 CFR 3403.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned or Controlled by Them 3403.602 Exceptions. Exceptions under FAR 3.602 must...

  1. An Impending Crisis: The Disappearance of Exceptionalities

    ERIC Educational Resources Information Center

    Coleman, Laurence J.

    1977-01-01

    A humorous satire on the proliferation of categories of exceptionalities, the article parodies current research by discussing the problem of disappearing exceptionalities in relation to imaginary interviews, research programs, and teacher reactions. (GW)

  2. Common cold

    MedlinePlus

    ... been tried for colds, such as vitamin C, zinc supplements, and echinacea. Talk to your health care ... nih.gov/pubmed/22962927 . Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic ...

  3. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  4. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  5. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  6. 48 CFR 8.706 - Purchase exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Purchase exceptions. 8.706... Blind or Severely Disabled 8.706 Purchase exceptions. (a) Ordering offices may acquire supplies or... in a purchase exception granted by the designated central nonprofit agency. (b) The central...

  7. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  8. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  9. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  10. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  11. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  12. 22 CFR 511.3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Exceptions. 511.3 Section 511.3 Foreign Relations BROADCASTING BOARD OF GOVERNORS FEDERAL TORT CLAIMS PROCEDURE § 511.3 Exceptions. Claims not compensable hereunder are listed in 2680 of the Act with the exception that 2680(k) (claims arising in...

  13. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  14. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  15. 22 CFR 511.3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Exceptions. 511.3 Section 511.3 Foreign Relations BROADCASTING BOARD OF GOVERNORS FEDERAL TORT CLAIMS PROCEDURE § 511.3 Exceptions. Claims not compensable hereunder are listed in 2680 of the Act with the exception that 2680(k) (claims arising in...

  16. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  17. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  18. Bullying and Victimization among Students with Exceptionalities

    ERIC Educational Resources Information Center

    Cummings, Joanne G.; Pepler, Debra J.; Mishna, Fay; Craig, Wendy M.

    2006-01-01

    Children and youth with exceptionalities are at increased risk to be marginalized in their peer group because of their exceptionalities; they are hence more vulnerable to victimization by peers who have higher status and more social power. Research also suggests that children and youth with exceptionalities may be more likely to bully others.…

  19. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  20. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  1. 48 CFR 25.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FOREIGN ACQUISITION Buy American-Supplies 25.103 Exceptions. When one of the following exceptions applies... Buy American statute: (a) Public interest. The head of the agency may make a determination that... has an agreement with a foreign government that provides a blanket exception to the Buy...

  2. 48 CFR 25.103 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOREIGN ACQUISITION Buy American Act-Supplies 25.103 Exceptions. When one of the following exceptions... the Buy American Act: (a) Public interest. The head of the agency may make a determination that... has an agreement with a foreign government that provides a blanket exception to the Buy American...

  3. 48 CFR 225.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... For example, a public interest exception may be appropriate— (1) If accepting the low domestic offer... not to impair integration of the military and commercial industrial base. (B) Except as provided in PGI 225.872-4, process a determination for a public interest exception after consideration of...

  4. 48 CFR 8.706 - Purchase exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Purchase exceptions. 8.706... Blind or Severely Disabled 8.706 Purchase exceptions. (a) Ordering offices may acquire supplies or... in a purchase exception granted by the designated central nonprofit agency. (b) The central...

  5. 40 CFR 46.125 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Exceptions. 46.125 Section 46.125 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE FELLOWSHIPS General § 46.125 Exceptions. The Director, Grants Administration Division, may approve exceptions...

  6. 40 CFR 46.125 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Exceptions. 46.125 Section 46.125 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE FELLOWSHIPS General § 46.125 Exceptions. The Director, Grants Administration Division, may approve exceptions...

  7. 40 CFR 46.125 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Exceptions. 46.125 Section 46.125 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE FELLOWSHIPS General § 46.125 Exceptions. The Director, Grants Administration Division, may approve exceptions...

  8. 40 CFR 46.125 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Exceptions. 46.125 Section 46.125 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE FELLOWSHIPS General § 46.125 Exceptions. The Director, Grants Administration Division, may approve exceptions...

  9. 40 CFR 46.125 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Exceptions. 46.125 Section 46.125 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE FELLOWSHIPS General § 46.125 Exceptions. The Director, Grants Administration Division, may approve exceptions...

  10. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  11. Major Advisor.

    ERIC Educational Resources Information Center

    Chatwin, Marshall

    This paper describes a computer program, Major Advisor (MA), which helps students identify college majors. Used in conjunction with career counseling and advising, MA provides information to students who are developing their educational plans. The program matches students' personal preferences and the requirements/characteristics of 130 common…

  12. Major Links.

    ERIC Educational Resources Information Center

    Henderson, Tona

    1995-01-01

    Provides electronic mail addresses for resources and discussion groups related to the following academic majors: art, biology, business, chemistry, computer science, economics, health sciences, history, literature, math, music, philosophy, political science, psychology, sociology, and theater. (AEF)

  13. A Year of Exceptional Achievements FY 2008

    SciTech Connect

    devore, L; Chrzanowski, P

    2008-11-06

    2008 highlights: (1) Stockpile Stewardship and Complex Transformation - LLNL achieved scientific breakthroughs that explain some of the key 'unknowns' in nuclear weapons performance and are critical to developing the predictive science needed to ensure the safety, reliability, and security of the U.S. nuclear deterrent without nuclear testing. In addition, the National Ignition Facility (NIF) passed 99 percent completion, an LLNL supercomputer simulation won the 2007 Gordon Bell Prize, and a significant fraction of our inventory of special nuclear material was shipped to other sites in support of complex transformation. (2) National and Global Security - Laboratory researchers delivered insights, technologies, and operational capabilities that are helping to ensure national security and global stability. Of particular note, they developed advanced detection instruments that provide increased speed, accuracy, specificity, and resolution for identifying and characterizing biological, chemical, nuclear, and high-explosive threats. (3) Exceptional Science and Technology - The Laboratory continued its tradition of scientific excellence and technical innovation. LLNL scientists made significant contributions to Nobel Prize-winning work on climate change. LLNL also received three R&D 100 awards and six Nanotech 50 awards, and dozens of Laboratory scientists and engineers were recognized with professional awards. These honors provide valuable confirmation that peers and outside experts recognize the quality of our staff and our work. (4) Enhanced Business and Operations - A major thrust under LLNS is to make the Laboratory more efficient and cost competitive. We achieved roughly $75 million in cost savings for support activities through organizational changes, consolidation of services, improved governance structures and work processes, technology upgrades, and systems shared with Los Alamos National Laboratory. We realized nonlabor cost savings of $23 million. Severe

  14. Common clay and shale

    USGS Publications Warehouse

    Virta, R.L.

    2006-01-01

    At present, 150 companies produce common clay and shale in 41 US states. According to the United States Geological Survey (USGS), domestic production in 2005 reached 24.8 Mt valued at $176 million. In decreasing order by tonnage, the leading producer states include North Carolina, Texas, Alabama, Georgia and Ohio. For the whole year, residential and commercial building construction remained the major market for common clay and shale products such as brick, drain tile, lightweight aggregate, quarry tile and structural tile.

  15. Occurrance in Korea of three major soybean viruses, Soybean mosaic virus (SMV), Soybean yellow mottle mosaic virus (SYCMV), and Soybean yellow common mosaic virus (SYCMV) revealed by a nationwide survey of soybean fields

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soybean yellow mottle mosaic virus (SYMMV) and soybean yellow common mosaic virus (SYCMV) were recently isolated in Korea, and it hasn’t been reported how these two viruses were dispersed in Korea. In 2012, we performed a nationwide survey of subsistence soybean farms in Korea. Leaves that appeared ...

  16. 48 CFR 1404.7003 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... operational purposes that have no public interest, educational, scientific, or research value; (b) Classified... MATTERS Deposit of Contract Publications 1404.7003 Exceptions. The following types of publications...

  17. Making the Common Good Common

    ERIC Educational Resources Information Center

    Chase, Barbara

    2011-01-01

    How are independent schools to be useful to the wider world? Beyond their common commitment to educate their students for meaningful lives in service of the greater good, can they educate a broader constituency and, thus, share their resources and skills more broadly? Their answers to this question will be shaped by their independence. Any…

  18. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  19. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  20. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  1. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  2. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  3. 33 CFR 159.311 - Safety exception.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety exception. 159.311 Section... Operations § 159.311 Safety exception. The regulations in this subpart shall not apply to discharges made for the purpose of securing the safety of the cruise vessel or saving life at sea, provided that...

  4. 33 CFR 159.311 - Safety exception.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Safety exception. 159.311 Section... Operations § 159.311 Safety exception. The regulations in this subpart shall not apply to discharges made for the purpose of securing the safety of the cruise vessel or saving life at sea, provided that...

  5. 33 CFR 159.311 - Safety exception.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety exception. 159.311 Section... Operations § 159.311 Safety exception. The regulations in this subpart shall not apply to discharges made for the purpose of securing the safety of the cruise vessel or saving life at sea, provided that...

  6. 33 CFR 159.311 - Safety exception.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety exception. 159.311 Section... Operations § 159.311 Safety exception. The regulations in this subpart shall not apply to discharges made for the purpose of securing the safety of the cruise vessel or saving life at sea, provided that...

  7. 33 CFR 159.311 - Safety exception.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Safety exception. 159.311 Section... Operations § 159.311 Safety exception. The regulations in this subpart shall not apply to discharges made for the purpose of securing the safety of the cruise vessel or saving life at sea, provided that...

  8. 7 CFR 1956.148 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Requests for exceptions must be made in writing by the State Director and supported with documentation to explain the adverse effect on the Government's interest, propose alternative courses of action, and show how the adverse effect will be eliminated or minimized if the exception is granted. Any...

  9. 7 CFR 1980.397 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... recommendation of the Assistant Administrator for Housing. Requests for exception must be made in writing... to explain the adverse effect, propose alternative courses of action, and to show how the adverse effect will be eliminated or minimized if the exception is granted....

  10. 8 CFR 258.2 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Exceptions. 258.2 Section 258.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS LIMITATIONS ON PERFORMANCE OF LONGSHORE WORK BY ALIEN CREWMEN § 258.2 Exceptions. Any master or agent who uses nonimmigrant crewmen to perform longshore work at any United...

  11. The Doubly Exceptional Child: A Principal's Dilemma.

    ERIC Educational Resources Information Center

    Kesner, Rebecca J., Ed.

    2002-01-01

    This document contains two articles concerned with doubly exceptional children and gifted education. In "The Doubly Exceptional Child: A Principal's Dilemma," (Carol J. Mills and Linda E. Brody), such children do not fit into the usual categories for sorting children because their gifts and disabilities often mask each other. Suggestions are…

  12. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for... Exceptional Program Selection Process shall reimburse NASA for Spacelab and Shuttle services on the...

  13. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for... Exceptional Program Selection Process shall reimburse NASA for Spacelab and Shuttle services on the...

  14. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for... Exceptional Program Selection Process shall reimburse NASA for Spacelab and Shuttle services on the...

  15. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for... Exceptional Program Selection Process shall reimburse NASA for Spacelab and Shuttle services on the...

  16. 48 CFR 3425.102 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Exceptions. 3425.102 Section 3425.102 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 3425.102 Exceptions. The HCA...

  17. 48 CFR 3425.102 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Exceptions. 3425.102 Section 3425.102 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 3425.102 Exceptions. The HCA...

  18. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  19. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  20. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  1. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  2. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  3. 7 CFR 500.14 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 500.14 Section 500.14 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL ARBORETUM Conduct on U.S. National Arboreturm Property § 500.14 Exceptions....

  4. 7 CFR 500.14 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 500.14 Section 500.14 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL ARBORETUM Conduct on U.S. National Arboreturm Property § 500.14 Exceptions....

  5. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Exceptions. 82.2 Section 82.2 Money and Finance: Treasury Regulations Relating to Money and Finance 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1 against the exportation of 5-cent coins...

  6. 24 CFR 91.20 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Exceptions. 91.20 Section 91.20 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development CONSOLIDATED SUBMISSIONS FOR COMMUNITY PLANNING AND DEVELOPMENT PROGRAMS General § 91.20 Exceptions. The...

  7. 24 CFR 91.20 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Exceptions. 91.20 Section 91.20 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development CONSOLIDATED SUBMISSIONS FOR COMMUNITY PLANNING AND DEVELOPMENT PROGRAMS General § 91.20 Exceptions. The...

  8. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  9. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  10. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  11. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  12. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  13. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  14. 48 CFR 725.403 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 725.403 Section 725.403 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Trade Agreements 725.403 Exceptions. FAR 25.4 establishes procedures for purchases under the Trade Agreements Act of...

  15. Physical Facilities: Exceptional Child Bibliography Series.

    ERIC Educational Resources Information Center

    Council for Exceptional Children, Reston, VA. Information Center on Exceptional Children.

    The annotated bibliography, one in a series of over 50 similar listings related to handicapped and gifted children, contains 91 references selected from Exceptional Child Education Abstracts dealing with physical facilities, educational or institutional, for exceptional children. The entries, which include texts, journal articles, research…

  16. 29 CFR 1921.14 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Exceptions. 1921.14 Section 1921.14 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED...' COMPENSATION ACT Decision and Order § 1921.14 Exceptions. Within 20 days after the date of the decision of...

  17. 40 CFR 170.203 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS WORKER PROTECTION STANDARD Standard for Pesticide Handlers § 170.203 Exceptions. Exceptions. This subpart does not apply when any pesticide is handled for use on an agricultural establishment in the following circumstances:...

  18. 32 CFR 536.45 - Statutory exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Statutory exceptions. 536.45 Section 536.45 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Investigation and Processing of Claims § 536.45 Statutory exceptions. This...

  19. 48 CFR 1903.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned or Controlled by Them 1903.602 Exceptions. To avoid potential conflicts of interest or the... business concerns owned or controlled by Government employees or their family members. Exceptions to...

  20. 48 CFR 1505.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Exceptions. 1505.202 Section 1505.202 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Synopses of Proposed Contract Actions 1505.202 Exceptions....

  1. 39 CFR 3055.3 - Reporting exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Reporting exceptions. 3055.3 Section 3055.3 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL SERVICE PERFORMANCE AND CUSTOMER SATISFACTION REPORTING Annual Reporting of Service Performance Achievements § 3055.3 Reporting exceptions. (a) The...

  2. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  3. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  4. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  5. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  6. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  7. 75 FR 38757 - Periodic Reporting Exceptions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... 39 CFR 3055 Periodic Reporting Exceptions AGENCY: Postal Regulatory Commission. ACTION: Notice of... to Postal Service-proposed semi-permanent exceptions to certain rules on periodic reporting of... INFORMATION: Table of Contents I. Introduction II. Ordering Paragraphs I. Introduction On June 25, 2010,...

  8. 48 CFR 625.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Exceptions. 625.103 Section 625.103 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 625.103 Exceptions. (a) The authority to make the...

  9. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  10. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  11. 48 CFR 625.103 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Exceptions. 625.103 Section 625.103 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 625.103 Exceptions. (a) The authority to make the...

  12. 48 CFR 625.103 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Exceptions. 625.103 Section 625.103 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 625.103 Exceptions. (a) The authority to make the...

  13. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  14. 45 CFR 1176.8 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Exceptions. 1176.8 Section 1176.8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES PART-TIME CAREER EMPLOYMENT § 1176.8 Exceptions. (a) The Personnel Officer...

  15. 45 CFR 1176.8 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Exceptions. 1176.8 Section 1176.8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES PART-TIME CAREER EMPLOYMENT § 1176.8 Exceptions. (a) The Personnel Officer...

  16. Twice Exceptionality from a Practitioner's Perspective

    ERIC Educational Resources Information Center

    Omdal, Stuart

    2015-01-01

    The new definition of twice exceptionality by the National Twice-Exceptional Community of Practice (2e CoP) is a tool that will facilitate communication and collaboration for practitioners in the regular classroom, gifted education specialists, administrators, and professors. In this article, the author shares his experiences in several of these…

  17. 19 CFR 10.41 - Instruments; exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Instruments; exceptions. 10.41 Section 10.41 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE... Traffic § 10.41 Instruments; exceptions. (a) Locomotives and other railroad equipment, trucks,...

  18. 32 CFR 536.45 - Statutory exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Statutory exceptions. 536.45 Section 536.45 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Investigation and Processing of Claims § 536.45 Statutory exceptions. This topic is more fully discussed in DA Pam...

  19. 7 CFR 1955.81 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exception authority. 1955.81 Section 1955.81 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.81 Exception...

  20. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  1. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  2. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  3. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  4. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  5. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  6. 45 CFR 1176.8 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Exceptions. 1176.8 Section 1176.8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES PART-TIME CAREER EMPLOYMENT § 1176.8 Exceptions. (a) The Personnel Officer...

  7. 45 CFR 1176.8 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Exceptions. 1176.8 Section 1176.8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES PART-TIME CAREER EMPLOYMENT § 1176.8 Exceptions. (a) The Personnel Officer...

  8. 45 CFR 1176.8 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Exceptions. 1176.8 Section 1176.8 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE HUMANITIES PART-TIME CAREER EMPLOYMENT § 1176.8 Exceptions. (a) The Personnel Officer...

  9. 27 CFR 555.182 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Exceptions. 555.182 Section 555.182 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE EXPLOSIVES COMMERCE IN EXPLOSIVES Marking of Plastic Explosives § 555.182 Exceptions. It is an affirmative defense...

  10. 48 CFR 625.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Exceptions. 625.202 Section 625.202 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 625.202 Exceptions. (a)(1) The authority to make...

  11. 48 CFR 625.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Exceptions. 625.202 Section 625.202 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 625.202 Exceptions. (a)(1) The authority to make...

  12. 48 CFR 625.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Exceptions. 625.202 Section 625.202 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 625.202 Exceptions. (a)(1) The authority to make...

  13. 48 CFR 625.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exceptions. 625.202 Section 625.202 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 625.202 Exceptions. (a)(1) The authority to make...

  14. 48 CFR 625.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Exceptions. 625.202 Section 625.202 Federal Acquisition Regulations System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 625.202 Exceptions. (a)(1) The authority to make...

  15. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $204,000, the exception for unreasonable cost may apply (see FAR...

  16. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $202,000, the exception for unreasonable cost may apply (see FAR...

  17. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $202,000, the exception for unreasonable cost may apply (see FAR...

  18. 40 CFR 180.4 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Definitions and Interpretative Regulations § 180.4 Exceptions. The substances listed in this section are excepted from the definitions of “pesticide chemical” and “pesticide chemical residue” under FFDCA section 201(q)(3) and are therefore exempt...

  19. 38 CFR 1.897 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Exceptions. 1.897 Section 1.897 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Part-Time Career Employment Program § 1.897 Exceptions. The Secretary of Veterans Affairs, or designees,...

  20. 38 CFR 1.897 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Exceptions. 1.897 Section 1.897 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Part-Time Career Employment Program § 1.897 Exceptions. The Secretary of Veterans Affairs, or designees,...

  1. Common clay and shale

    USGS Publications Warehouse

    Virta, R.L.

    2001-01-01

    Part of the 2000 annual review of the industrial minerals sector. A general overview of the common clay and shale industry is provided. In 2000, U.S. production increased by 5 percent, while sales or use declined to 23.6 Mt. Despite the slowdown in the economy, no major changes are expected for the market.

  2. A Language in Common.

    ERIC Educational Resources Information Center

    1963

    This collection of articles reprinted from the "London Times Literary Supplement" indicates the flexibility of English as a common literary language in its widespread use outside the United States and England. Major articles present the thesis that English provides an artistic medium which is enriched through colloquial idioms in the West Indies…

  3. The Exception Does Not Rule: Attention Constrains Form Preparation in Word Production

    PubMed Central

    O’Séaghdha, Pádraig G.; Frazer, Alexandra K.

    2014-01-01

    Form preparation in word production, the benefit of exploiting a useful common sound (such as the first phoneme) of iteratively spoken small groups of words, is notoriously fastidious, exhibiting a seemingly categorical, all-or-none character, and a corresponding susceptibility to ‘killers’ of preparation. In particular, the presence of a single exception item in a group of otherwise phonologically consistent words has been found to eliminate the benefit of knowing a majority characteristic. This has been interpreted to mean that form preparation amounts to partial production, and thus provides a window on fundamental processes of phonological word encoding (e.g., Levelt et al., 1999). However, preparation of only fully distributed properties appears to be non-optimal, and is difficult to reconcile with the sensitivity of cognitive responses to probabilities in other domains. We show here that the all-or-none characteristic of form preparation is specific to task format. Preparation for sets that included an exception item occurred in ecologically valid production tasks, picture naming (Experiment 1), and word naming (Experiment 2). Preparation failed only in the commonly used, but indirect and resource-intensive, associative cuing task (Experiment 3). We outline an account of form preparation in which anticipation of word-initial phonological fragments uses a limited capacity, sustained attentional capability that points to rather than enacts possibilities for imminent speech. PMID:24548328

  4. Exceptions Handling within GLARE Clinical Guideline Framework

    PubMed Central

    Leonardi, Giorgio; Bottrighi, Alessio; Galliani, Gabriele; Terenziani, Paolo; Messina, Antonio; Corte, Francesco Della

    2012-01-01

    Computerized clinical guidelines (CIGs) are widely adopted in order to assist practitioner and patient decision making. However, a main problem in their adoption is the fact that, during guidelines executions on specific patients, unpredictable facts and conditions (henceforth called exceptions) may occur. A proper and immediate treatment of such exception is necessary, but most current software systems coping with CIGs do not support it. In this paper, we describe how the GLARE system has been extended to deal with exceptions in CIGs. PMID:23304323

  5. 50 CFR 300.39 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Pacific Tuna Fisheries § 300.39 Exceptions. (a) The prohibitions of § 300.38 and the licensing requirements of § 300.32 do not apply to fishing for albacore tuna by vessels using the trolling method or...

  6. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  7. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  8. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  9. 33 CFR 175.115 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SAFETY EQUIPMENT REQUIREMENTS Visual Distress Signals § 175.115 Exceptions. The following persons need not comply with § 175.110; however, each must carry on board visual distress signals suitable...

  10. 32 CFR 811.1 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SALE OF VISUAL INFORMATION MATERIALS § 811.1 Exceptions. The regulations in this part do not apply to: (a) Visual information (VI) materials made for the Air Force Office of Special Investigations for...

  11. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards in 36 CFR part 1194 would be an undue burden, an agency must consider— (i) The difficulty...

  12. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards in 36 CFR part 1194 would be an undue burden, an agency must consider— (i) The difficulty...

  13. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards in 36 CFR part 1194 would be an undue burden, an agency must consider— (i) The difficulty...

  14. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards in 36 CFR part 1194 would be an undue burden, an agency must consider— (i) The difficulty...

  15. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards in 36 CFR part 1194 would be an undue burden, an agency must consider— (i) The difficulty...

  16. 48 CFR 223.7102 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Storage and Disposal of Toxic and Hazardous... applies, may grant exceptions to the prohibition of 10 U.S.C. 2692 when essential to protect the...

  17. 48 CFR 223.7102 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Storage and Disposal of Toxic and Hazardous... applies, may grant exceptions to the prohibition of 10 U.S.C. 2692 when essential to protect the...

  18. 48 CFR 223.7102 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Storage and Disposal of Toxic and Hazardous... applies, may grant exceptions to the prohibition of 10 U.S.C. 2692 when essential to protect the...

  19. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  20. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  1. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority. The... not inconsistent with the authorizing statute or other applicable law and is determined to be in...

  2. 7 CFR 1780.25 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.25 Exception... this part which is not inconsistent with the authorizing statute or other applicable law and...

  3. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority. The... not inconsistent with the authorizing statute or other applicable law and is determined to be in...

  4. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority. The... not inconsistent with the authorizing statute or other applicable law and is determined to be in...

  5. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  6. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  7. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  8. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  9. 15 CFR 1180.7 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION, DEPARTMENT OF COMMERCE TRANSFER BY FEDERAL AGENCIES OF SCIENTIFIC, TECHNICAL AND ENGINEERING INFORMATION TO THE NATIONAL TECHNICAL INFORMATION SERVICE § 1180.7 Exceptions. (a) An agency shall not...

  10. 22 CFR 513.625 - Exception provision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Drug-Free Workplace Requirements (Grants) § 513.625 Exception provision. The Board head may waive with respect to a particular grant, in writing, a...

  11. 44 CFR 17.625 - Exception provision.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HOMELAND SECURITY GENERAL GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) § 17.625 Exception provision. The agency head may waive with respect to a particular grant, in writing, a suspension...

  12. 48 CFR 217.7404-5 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7404-5 Exceptions. (a) The limitations in 217.7404-2, 217.7404-3, and 217.7404-4...

  13. 48 CFR 217.7404-5 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7404-5 Exceptions. (a) The limitations in 217.7404-2, 217.7404-3, and 217.7404-4...

  14. 48 CFR 217.7404-5 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7404-5 Exceptions. (a) The limitations in 217.7404-2, 217.7404-3, and 217.7404-4...

  15. 48 CFR 217.7404-5 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7404-5 Exceptions. (a) The limitations in 217.7404-2, 217.7404-3, and 217.7404-4...

  16. 48 CFR 217.7404-5 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7404-5 Exceptions. (a) The limitations in 217.7404-2, 217.7404-3, and 217.7404-4...

  17. 48 CFR 425.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 425.202 Exceptions. (a) The SPE shall make the... domestic construction material should be waived for a contract on the grounds that its use would...

  18. 48 CFR 425.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 425.202 Exceptions. (a) The SPE shall make the... domestic construction material should be waived for a contract on the grounds that its use would...

  19. 48 CFR 925.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACQUISITION Buy American Act-Construction Materials 925.202 Exceptions. (a)(2) Contracting officers may make the determination required by 48 CFR 25.202(a)(2), if the cost of the materials is not expected...

  20. 48 CFR 925.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ACQUISITION Buy American Act-Construction Materials 925.202 Exceptions. (a)(2) Contracting officers may make the determination required by 48 CFR 25.202(a)(2), if the cost of the materials is not expected...

  1. 48 CFR 425.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 425.202 Exceptions. (a) The SPE shall make the... domestic construction material should be waived for a contract on the grounds that its use would...

  2. 48 CFR 925.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ACQUISITION Buy American Act-Construction Materials 925.202 Exceptions. (a)(2) Contracting officers may make the determination required by 48 CFR 25.202(a)(2), if the cost of the materials is not expected...

  3. 48 CFR 425.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 425.202 Exceptions. (a) The SPE shall make the... domestic construction material should be waived for a contract on the grounds that its use would...

  4. 48 CFR 925.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ACQUISITION Buy American Act-Construction Materials 925.202 Exceptions. (a)(2) Contracting officers may make the determination required by 48 CFR 25.202(a)(2), if the cost of the materials is not expected...

  5. 48 CFR 425.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 425.202 Exceptions. (a) The SPE shall make the... domestic construction material should be waived for a contract on the grounds that its use would...

  6. 42 CFR 411.357 - Exceptions to the referral prohibition related to compensation arrangements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...), except that the lessee may make payments for the use of space consisting of common areas if the payments... used exclusively by the lessee to the total amount of space (other than common areas) occupied by all persons using the common areas. (4) The rental charges over the term of the agreement are set in...

  7. Syrtis Major

    NASA Technical Reports Server (NTRS)

    2002-01-01

    (Released 1 May 2002) The Science This image is from the region of Syrtis Major, which is dominated by a low-relief shield volcano. This area is believed to be an area of vigorous aeolian activity with strong winds in the east-west direction. The effects of these winds are observed as relatively bright streaks across the image, extending from topographic features such as craters. The brighter surface material probably indicates a smaller relative particle size in these areas, as finer particles have a higher albedo. The bright streaks seen off of craters are believed to have formed during dust storms. A raised crater rim can cause a reduction in the wind velocity directly behind it, which results in finer particles being preferentially deposited in this location. In the top half of the image, there is a large bright streak that crosses the entire image. There is no obvious topographic obstacle, therefore it is unclear whether it was formed in the same manner as described above. This image is located northwest of Nili Patera, a large caldera in Syrtis Major. Different flows from the caldera eruptions can be recognized as raised ridges, representing the edge of a flow lobe. The Story In the 17th century, Holland was in its Golden Age, a time of cultural greatness and immense political and economic influence in the world. In that time, lived a inquisitive person named Christian Huygens. As a boy, he loved to draw and to figure out problems in mathematics. As a man, he used these talents to make the first detailed drawings of the Martian surface - - only 50 years or so after Galileo first turned his telescope on Mars. Mars suddenly became something other than a small red dot in the sky. One of the drawings Huygens made was of a dark marking on the red planet's surface named Syrtis Major. Almost 350 years later, here we are with an orbiter that can show us this place in detail. Exploration lives! It's great we can study this area up close. In earlier periods of history

  8. THE CONCEPT OF EXCEPTIONALITY: A LEGAL FARCE?

    PubMed Central

    Ford, Amy

    2012-01-01

    How do we decide which treatments should be offered by the National Health Service (NHS) when we cannot afford to fund them all? In the absence of a positive appraisal by the National Institute for Health and Clinical Excellence (NICE), which mandates the provision of a treatment by the NHS, Primary Care Trusts (PCTs) are free to decide whether to provide a particular drug to some, or all, of their population. However, as public bodies, it is a well-established principle of Administrative Law that PCTs are not at liberty to fetter the exercise of their own discretion. They must recognise the possibility that some patients will have exceptional circumstances, and as a consequence, any general policy prohibiting the funding of a drug cannot be absolute. In the absence of statutory guidance on what might constitute exceptional, clinicians are left guessing as to whether their patients might be eligible for funding on the grounds of exceptionality. Using the context of expensive cancer drugs, I will examine the concept of exceptionality from clinical, moral, and legal perspectives, focussing particularly on the role of social factors in determining exceptionality. I will review the cases where PCTs' decisions not to fund cancer drugs were subject to legal action and argue that the courts have provided little guidance on interpreting the term exceptional, and that the concept has a limited role to play in the allocation of scarce health resources at a local level. PMID:22389444

  9. Common Cause Failure Modes

    NASA Technical Reports Server (NTRS)

    Wetherholt, Jon; Heimann, Timothy J.; Anderson, Brenda

    2011-01-01

    High technology industries with high failure costs commonly use redundancy as a means to reduce risk. Redundant systems, whether similar or dissimilar, are susceptible to Common Cause Failures (CCF). CCF is not always considered in the design effort and, therefore, can be a major threat to success. There are several aspects to CCF which must be understood to perform an analysis which will find hidden issues that may negate redundancy. This paper will provide definition, types, a list of possible causes and some examples of CCF. Requirements and designs from NASA projects will be used in the paper as examples.

  10. Syrtis Major

    NASA Technical Reports Server (NTRS)

    2002-01-01

    (Released 6 June 2002) The Science This image, located near the equator and 288W (72E), is near the southern edge of a low, broad volcanic feature called Syrtis Major. A close look at this image reveals a wrinkly texture that indicates a very rough surface that is associated with the lava flows that cover this region. On a larger scale, there are numerous bright streaks that trail topographic features such as craters. These bright streaks are in the wind shadows of the craters where dust that settles onto the surface is not as easily scoured away. It is important to note that these streaks are only bright in a relative sense to the surrounding image. Syrtis Major is one of the darkest regions on Mars and it is as dark as fresh basalt flows or dunes are on Earth. The Story Cool! It almost looks as if nature has 'painted' comets on the surface of Mars, using craters as comet cores and dust as streaky tails. Of course, that's just an illusion. As in many areas of Mars, the wind is behind the creation of such fantastic landforms. The natural phenomenon seen here gives this particular surface of Mars a very dynamic, fast-moving, almost luminous 'cosmic personality.' The bright, powdery-looking streaks of dust are in the 'wind shadows' of craters, where dust that settles onto the surface is not as easily scoured away. That's because the wind moves across the land in a particular direction, and a raised surface like the rim of a crater 'protects' dust from being completely blown away on the other side. The raised landforms basically act as a buffer. From the streaks seen above, you can tell the wind was blowing in a northeast to southwest direction. Why are the streaks so bright? Because they contrast with the really dark underlying terrain in this volcanic area of Mars. Syrtis Major is one of the darkest regions on Mars because it is made of basalt. Basalt is typically dark gray or black, and forms when a certain type of molten lava cools. The meaning of the word basalt

  11. 7 CFR 767.251 - Agency exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGRICULTURE SPECIAL PROGRAMS INVENTORY PROPERTY MANAGEMENT Exception Authority § 767.251 Agency exception... accordance with published regulations or policies and granting the exception would reduce or eliminate...

  12. 'A major lobbying effort to change and unify the excise structure in six Central American countries': How British American Tobacco influenced tax and tariff rates in the Central American Common Market

    PubMed Central

    2011-01-01

    Background Transnational tobacco companies (TTCs) may respond to processes of regional trade integration both by acting politically to influence policy and by reorganising their own operations. The Central American Common Market (CACM) was reinvigorated in the 1990s, reflecting processes of regional trade liberalisation in Latin America and globally. This study aimed to ascertain how British American Tobacco (BAT), which dominated the markets of the CACM, sought to influence policy towards it by member country governments and how the CACM process impacted upon BAT's operations. Methods The study analysed internal tobacco industry documents released as a result of litigation in the US and available from the online Legacy Tobacco Documents Library at http://legacy.library.ucsf.edu/. Documents were retrieved by searching the BAT collection using key terms in an iterative process. Analysis was based on an interpretive approach involving a process of attempting to understand the meanings of individual documents and relating these to other documents in the set, identifying the central themes of documents and clusters of documents, contextualising the documentary data, and choosing representative material in order to present findings. Results Utilising its multinational character, BAT was able to act in a coordinated way across the member countries of the CACM to influence tariffs and taxes to its advantage. Documents demonstrate a high degree of access to governments and officials. The company conducted a coordinated, and largely successful, attempt to keep external tariff rates for cigarettes high and to reduce external tariffs for key inputs, whilst also influencing the harmonisation of excise taxes between countries. Protected by these high external tariffs, it reorganised its own operations to take advantage of regional economies of scale. In direct contradiction to arguments presented to CACM governments that affording the tobacco industry protection via high

  13. Rates of homicide and suicide on major national holidays.

    PubMed

    Bridges, F Stephen

    2004-04-01

    Rates of U.S. homicides and suicides during 1972-1979 were higher on 7 major national holidays except one for homicides and were lower for suicides, except New Year's Day as Lester noted for 1972-1979.

  14. 15 CFR 740.20 - License Exception Strategic Trade Authorization (STA).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Exception STA may not be used for 9D001 or 9D002 “software” that is specially designed or modified for the... by 9B001. (B) License Exception STA may not be used for 9D001 “software” that is specially designed... Major Defense Equipment” and the value of such items in the contract requiring their export exceeds...

  15. Exceptional sets for nonuniformly expanding maps

    NASA Astrophysics Data System (ADS)

    Campos, Sara; Gelfert, Katrin

    2016-04-01

    Given a rational map of the Riemann sphere and a subset A of its Julia set, we study the A-exceptional set, that is, the set of points whose orbit does not accumulate at A. We prove that if the topological entropy of A is less than the topological entropy of the full system then the A-exceptional set has full topological entropy. Furthermore, if the Hausdorff dimension of A is smaller than the dynamical dimension of the system then the Hausdorff dimension of the A-exceptional set is larger than or equal to the dynamical dimension, with equality in the particular case when the dynamical dimension and the Hausdorff dimension coincide. We also discuss the case of a general conformal {{C}1+α} dynamical system and, in particular, certain multimodal interval maps on their Julia set.

  16. Amendments to excepted benefits. Final rules.

    PubMed

    2014-10-01

    This document contains final regulations that amend the regulations regarding excepted benefits under the Employee Retirement Income Security Act of 1974, the Internal Revenue Code (the Code), and the Public Health Service Act. Excepted benefits are generally exempt from the health reform requirements that were added to those laws by the Health Insurance Portability and Accountability Act and the Patient Protection and Affordable Care Act. In addition, eligibility for excepted benefits does not preclude an individual from eligibility for a premium tax credit under section 36B of the Code if an individual chooses to enroll in coverage under a Qualified Health Plan through an Affordable Insurance Exchange. These regulations finalize some but not all of the proposed rules with minor modifications; additional guidance on limited wraparound coverage is forthcoming.

  17. Amendments to excepted benefits. Final rules.

    PubMed

    2014-10-01

    This document contains final regulations that amend the regulations regarding excepted benefits under the Employee Retirement Income Security Act of 1974, the Internal Revenue Code (the Code), and the Public Health Service Act. Excepted benefits are generally exempt from the health reform requirements that were added to those laws by the Health Insurance Portability and Accountability Act and the Patient Protection and Affordable Care Act. In addition, eligibility for excepted benefits does not preclude an individual from eligibility for a premium tax credit under section 36B of the Code if an individual chooses to enroll in coverage under a Qualified Health Plan through an Affordable Insurance Exchange. These regulations finalize some but not all of the proposed rules with minor modifications; additional guidance on limited wraparound coverage is forthcoming. PMID:25341261

  18. Exceptional points in coupled dissipative dynamical systems.

    PubMed

    Ryu, Jung-Wan; Son, Woo-Sik; Hwang, Dong-Uk; Lee, Soo-Young; Kim, Sang Wook

    2015-05-01

    We study the transient behavior in coupled dissipative dynamical systems based on the linear analysis around the steady state. We find that the transient time is minimized at a specific set of system parameters and show that at this parameter set, two eigenvalues and two eigenvectors of the Jacobian matrix coalesce at the same time; this degenerate point is called the exceptional point. For the case of coupled limit-cycle oscillators, we investigate the transient behavior into the amplitude death state, and clarify that the exceptional point is associated with a critical point of frequency locking, as well as the transition of the envelope oscillation.

  19. The exceptional story of massive IIA supergravity

    NASA Astrophysics Data System (ADS)

    Ciceri, Franz; Guarino, Adolfo; Inverso, Gianluca

    2016-08-01

    The framework of exceptional field theory is extended by introducing consistent deformations of its generalised Lie derivative. For the first time, massive type IIA super-gravity is reproduced geometrically as a solution of the section constraint. This provides a unified description of all ten- and eleven-dimensional maximal supergravities. The actionof the E7(7) deformed theory is constructed, and reduces to those of exceptional field theory and gauged maximal supergravity in respective limits. The relation of this new framework to other approaches for generating the Romans mass non-geometrically is discussed.

  20. Reading: Exceptional Child Education Curriculum K-12.

    ERIC Educational Resources Information Center

    Biddle, Candace Thornton; And Others

    This K-12 reading curriculum for exceptional child education is arranged in a format comparable to the general education curriculum, and is sequenced in the order in which most children learn. The curriculum begins with a list of 123 objectives of the reading program. The objectives cover the areas of perceptual skills, word attack, structural…

  1. Mathematics. Exceptional Child Education Curriculum K-12.

    ERIC Educational Resources Information Center

    Jordon, Thelma; And Others

    The mathematics curriculum provides a framework of instruction for exceptional child education in grades K-12. Content areas include: numeration, whole numbers, rational numbers, real/complex numbers, calculator literacy, measurement, geometry, statistics, functions/relations, computer literacy, and pre-algebra. The guide is organized by content…

  2. Voices from the Classroom: Exceptional Teachers Speak.

    ERIC Educational Resources Information Center

    Maeroff, Gene I., Ed.

    The opinions and experiences reflected in this report are those of exceptional teachers chosen in a national competition, "Thanks to Teachers," sponsored by Apple Computer, Inc., the National Foundation for the Improvement of Education, the National Alliance of Business, and Group W Television. The report is divided into four sections: (1) the…

  3. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision. may... proposed for debarment under 48 CFR part 9, subpart 9.4, to participate in a particular covered transaction upon a written determination by the agency head or an authorized designee stating the reason(s)...

  4. 7 CFR 1955.21 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .../or safety of tenants or the community are endangered if there is no adverse effect on the Government... the appropriate program Assistant Administrator. Requests for exceptions must be made in writing and supported with documentation to explain the adverse effect, propose alternative courses of action, and...

  5. 7 CFR 1955.149 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... exceptions must be made in writing and supported with documentation to explain the adverse effect, propose alternative courses of action, and show how the adverse effect will be eliminated or minimized if the... endangered if there is no adverse effect on the Government's interest. The Administrator will exercise...

  6. Streamlining Exceptional Student Placement with PERT.

    ERIC Educational Resources Information Center

    Radencich, Marguerite C.

    1985-01-01

    The article explains the usefulness of PERT (Program Evaluation and Review Technique) in streamlining exceptional student referral processes. With PERT, realistic time and personnel needs can be established, and the status of every referral can be known at all times. The initial step in PERT breaks the process into small manageable units and…

  7. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  8. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  9. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  10. 48 CFR 1505.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Exceptions. 1505.202 Section 1505.202 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY ACQUISITION... in writing that the contract is for the services of experts for use in preparing or prosecuting...

  11. 48 CFR 1505.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Exceptions. 1505.202 Section 1505.202 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY ACQUISITION... in writing that the contract is for the services of experts for use in preparing or prosecuting...

  12. 48 CFR 1505.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Exceptions. 1505.202 Section 1505.202 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY ACQUISITION... in writing that the contract is for the services of experts for use in preparing or prosecuting...

  13. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Exceptions. 5.202 Section 5.202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING... contract action is made under conditions described in 6.302-3 with respect to the services of an expert...

  14. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  15. 50 CFR 300.39 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES INTERNATIONAL FISHERIES REGULATIONS South Pacific Tuna Fisheries § 300.39 Exceptions. (a) The prohibitions of § 300.38 and the licensing requirements of § 300.32 do not apply to fishing for albacore tuna by vessels using the trolling method or...

  16. 48 CFR 1503.602 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees or Organizations.... 205, 18 U.S.C. 207, 18 U.S.C. 208, or EPA regulations at 40 CFR part 3. The Assistant Administrator shall consult with the Designated Agency Ethics Official before authorizing any exceptions....

  17. 48 CFR 1503.602 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees or Organizations.... 205, 18 U.S.C. 207, 18 U.S.C. 208, or EPA regulations at 40 CFR part 3. The Assistant Administrator shall consult with the Designated Agency Ethics Official before authorizing any exceptions....

  18. 24 CFR 51.105 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... all the following conditions are satisfied: (1) The project does not require an Environmental Impact Statement under provisions of § 51.104(b)(1) and noise is the only environmental issue. (2) The project has... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for...

  19. 24 CFR 51.105 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... all the following conditions are satisfied: (1) The project does not require an Environmental Impact Statement under provisions of § 51.104(b)(1) and noise is the only environmental issue. (2) The project has... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for...

  20. 24 CFR 51.105 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... all the following conditions are satisfied: (1) The project does not require an Environmental Impact Statement under provisions of § 51.104(b)(1) and noise is the only environmental issue. (2) The project has... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for...

  1. 24 CFR 51.105 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... all the following conditions are satisfied: (1) The project does not require an Environmental Impact Statement under provisions of § 51.104(b)(1) and noise is the only environmental issue. (2) The project has... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for...

  2. 24 CFR 51.105 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... all the following conditions are satisfied: (1) The project does not require an Environmental Impact Statement under provisions of § 51.104(b)(1) and noise is the only environmental issue. (2) The project has... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for...

  3. 7 CFR 4287.303 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Exception authority. 4287.303 Section 4287.303 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE SERVICING Servicing Biorefinery Assistance...

  4. 7 CFR 4287.303 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Exception authority. 4287.303 Section 4287.303 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE SERVICING Servicing Biorefinery Assistance...

  5. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  6. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  7. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  8. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... from 3 p.m. through 7:59 p.m., local time; and (c) O'Hare International Airport from 9:15 p.m. to...

  9. 77 FR 67838 - Excepted Service; September 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    .../2012 SELECTIVE SERVICE SYSTEM Office of the Director Chief of Staff....... SS120004 9/21/2012... MANAGEMENT Excepted Service; September 2012 AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice... CONTACT: Senior Executive Resources Services, Executive Resources and Employee Development,...

  10. 48 CFR 225.7004-3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Exceptions. 225.7004-3 Section 225.7004-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... apply in any of the following circumstances: (a) Buses manufactured outside the United States and...

  11. 48 CFR 225.7004-3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Exceptions. 225.7004-3 Section 225.7004-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... apply in any of the following circumstances: (a) Buses manufactured outside the United States and...

  12. 48 CFR 225.7004-3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Exceptions. 225.7004-3 Section 225.7004-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... apply in any of the following circumstances: (a) Buses manufactured outside the United States and...

  13. 48 CFR 225.7004-3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Exceptions. 225.7004-3 Section 225.7004-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... apply in any of the following circumstances: (a) Buses manufactured outside the United States and...

  14. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... (c)-(e) (f) Detonators containing no more than 1 g explosive (excluding ignition and delay charges... which case they are excepted from the packaging requirements of § 173.62: (1) No more than 50 detonators... compartment is used as the outer packaging; (3) No more than 1000 detonators in one outer packaging; and...

  15. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Detonators containing no more than 1 g explosive (excluding ignition and delay charges) that are electric... excepted from the packaging requirements of § 173.62: (1) No more than 50 detonators in one inner packaging... outer packaging; (3) No more than 1000 detonators in one outer packaging; and (4) No material may...

  16. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... packagings. (c)-(e) (f) Detonators containing no more than 1 g explosive (excluding ignition and delay... which case they are excepted from the packaging requirements of § 173.62: (1) No more than 50 detonators... compartment is used as the outer packaging; (3) No more than 1000 detonators in one outer packaging; and...

  17. Architectural Considerations for Classrooms for Exceptional Children.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    Definitions are provided of the following exceptionalities: blind, partially sighted, physically handicapped, minimally brain injured, deaf, educable mentally retarded (primary, junior, and senior high levels), trainable mentally retarded, speech handicapped, and emotionally disturbed. Architectural guidelines specify classroom location, size,…

  18. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  19. 40 CFR 1517.4 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Exceptions. 1517.4 Section 1517.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY PUBLIC MEETING PROCEDURES OF THE COUNCIL ON...) Disclose the identity of a confidential source and, in the case of a record compiled by a criminal...

  20. Transition and Students with Twice Exceptionality

    ERIC Educational Resources Information Center

    Prior, Susan

    2013-01-01

    "Twice exceptional" is one of the terms used to describe students who have giftedness and a disability. This is a small heterogeneous population of individual learners who are underserved in special, gifted, and mainstream education settings. Despite the availability of research on transition for students with disabilities, there is…

  1. 23 CFR 774.13 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Exceptions. 774.13 Section 774.13 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT PARKS, RECREATION AREAS... include, but are not limited to: (a) Restoration, rehabilitation, or maintenance of...

  2. 23 CFR 774.13 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Exceptions. 774.13 Section 774.13 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT PARKS, RECREATION AREAS... include, but are not limited to: (a) Restoration, rehabilitation, or maintenance of...

  3. 23 CFR 774.13 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Exceptions. 774.13 Section 774.13 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT PARKS, RECREATION AREAS... include, but are not limited to: (a) Restoration, rehabilitation, or maintenance of...

  4. 48 CFR 803.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 803.602 Section 803.602 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or...

  5. 48 CFR 1303.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 1303.602 Section 1303.602 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned...

  6. 48 CFR 603.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exceptions. 603.602 Section 603.602 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees or Organizations Owned...

  7. 48 CFR 3.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Exceptions. 3.602 Section 3.602 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or...

  8. 48 CFR 303.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exceptions. 303.602 Section 303.602 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned...

  9. 48 CFR 403.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exceptions. 403.602 Section 403.602 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned...

  10. 48 CFR 25.103 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the Buy American Act: (a) Public interest. The head of the agency may make a determination that domestic preference would be inconsistent with the public interest. This exception applies when an agency... the contracting officer learns at any time before the time designated for receipt of bids in...

  11. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  12. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  13. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  14. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  15. 48 CFR 1503.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees or Organizations.... 205, 18 U.S.C. 207, 18 U.S.C. 208, or EPA regulations at 40 CFR part 3. The Assistant Administrator shall consult with the Designated Agency Ethics Official before authorizing any exceptions....

  16. Conferencing and Compassion for an Exceptional Student

    ERIC Educational Resources Information Center

    Shafer, Gregory

    2011-01-01

    This essay is about the process of discovering and trying to help an exceptional student who was grappling with issues of real-life violence and incarceration and the desire to articulate their meaning to his life through writing. It describes how this student empowered himself to reflect on and deconstruct the meaning of his incarceration and how…

  17. 49 CFR 391.2 - General exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... commercial motor vehicle is used to— (1) Transport farm machinery, supplies, or both, to or from a farm for custom-harvesting operations on a farm; or (2) Transport custom-harvested crops to storage or market. (b) Apiarian industries. The rules in this part except for § 391.15(e) do not apply to a driver who...

  18. 7 CFR 1956.99 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exception authority. 1956.99 Section 1956.99 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) DEBT SETTLEMENT Debt Settlement-Farm Loan Programs and...

  19. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  20. 14 CFR 34.9 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Exceptions. 34.9 Section 34.9 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT FUEL VENTING AND EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES General Provisions § 34.9...

  1. 26 CFR 1.306-2 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... dividends and isolated dispositions of section 306 stock by minority shareholders. Similarly, in the absence... TAXES Effects on Recipients § 1.306-2 Exception. (a) If a shareholder terminates his entire stock.... In determining whether a shareholder has terminated his entire interest in a corporation by...

  2. Gifted and Learning Disabled: Twice Exceptional Students.

    ERIC Educational Resources Information Center

    Beckley, Dawn

    This paper discusses the characteristics, identification, and curriculum needs of gifted students who also have learning disabilities. Three different subgroups of twice-exceptional students are described: (1) students who have been identified as gifted yet are exhibiting difficulties in school; (2) students identified as having learning…

  3. 40 CFR 761.217 - Exception reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 761.217 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.217 Exception reporting. (a)(1) A generator of PCB waste, who does not receive a copy of the manifest with the handwritten signature of the owner...

  4. 40 CFR 761.217 - Exception reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 761.217 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.217 Exception reporting. (a)(1) A generator of PCB waste, who does not receive a copy of the manifest with the handwritten signature of the owner...

  5. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  6. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  7. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  8. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... resale. (6) Acquisitions of items for test and evaluation under the foreign comparative testing program.... (2)(i) Commercially available off-the-shelf (COTS) items containing specialty metals, except the..., subsystems, assemblies, or components. Specialty metal supply contracts issued by COTS producers are...

  9. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of items for test and evaluation under the foreign comparative testing program (10 U.S.C. 2350a(g... available off-the-shelf (COTS) items containing specialty metals, except the restrictions do apply to..., or components. Specialty metal supply contracts issued by COTS producers are not subcontracts for...

  10. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... resale. (6) Acquisitions of items for test and evaluation under the foreign comparative testing program.... (2)(i) Commercially available off-the-shelf (COTS) items containing specialty metals, except the..., subsystems, assemblies, or components. Specialty metal supply contracts issued by COTS producers are...

  11. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... resale. (6) Acquisitions of items for test and evaluation under the foreign comparative testing program.... (2)(i) Commercially available off-the-shelf (COTS) items containing specialty metals, except the..., subsystems, assemblies, or components. Specialty metal supply contracts issued by COTS producers are...

  12. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  13. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  14. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  15. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... § 5.202, see the List of CFR Sections Affected, which appears in the Finding Aids section of the... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 5.202 Section 5.202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION...

  16. 50 CFR 300.39 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... South Pacific Tuna Fisheries § 300.39 Exceptions. (a) The prohibitions of § 300.38 and the licensing requirements of § 300.32 do not apply to fishing for albacore tuna by vessels using the trolling method or...

  17. 50 CFR 300.39 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... South Pacific Tuna Fisheries § 300.39 Exceptions. (a) The prohibitions of § 300.38 and the licensing requirements of § 300.32 do not apply to fishing for albacore tuna by vessels using the trolling method or...

  18. 50 CFR 300.39 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... South Pacific Tuna Fisheries § 300.39 Exceptions. (a) The prohibitions of § 300.38 and the licensing requirements of § 300.32 do not apply to fishing for albacore tuna by vessels using the trolling method or...

  19. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... on an individual, or in the personal effects of an individual, departing from a place subject to the... TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1...) The exportation in any one shipment of 5-cent coins and one-cent coins having an aggregate face...

  20. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... on an individual, or in the personal effects of an individual, departing from a place subject to the... TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1...) The exportation in any one shipment of 5-cent coins and one-cent coins having an aggregate face...

  1. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... on an individual, or in the personal effects of an individual, departing from a place subject to the... TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1...) The exportation in any one shipment of 5-cent coins and one-cent coins having an aggregate face...

  2. 49 CFR 213.4 - Excepted track.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... required to be placarded by the Hazardous Materials Regulations (49 CFR part 172), are moved over the track... be placarded by the Hazardous Materials Regulations (49 CFR part 172); and (4) The gage on excepted... subjected to simultaneous use at speeds in excess of 10 miles per hour; (c) The identified segment...

  3. 49 CFR 213.4 - Excepted track.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... required to be placarded by the Hazardous Materials Regulations (49 CFR part 172), are moved over the track... be placarded by the Hazardous Materials Regulations (49 CFR part 172); and (4) The gage on excepted... subjected to simultaneous use at speeds in excess of 10 miles per hour; (c) The identified segment...

  4. 29 CFR 1905.28 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Exceptions. 1905.28 Section 1905.28 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR RULES OF PRACTICE FOR VARIANCES, LIMITATIONS, VARIATIONS, TOLERANCES, AND EXEMPTIONS UNDER THE...

  5. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... on an individual, or in the personal effects of an individual, departing from a place subject to the... TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1...) The exportation in any one shipment of 5-cent coins and one-cent coins having an aggregate face...

  6. 48 CFR 1404.7003 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... operational purposes that have no public interest, educational, scientific, or research value; (b) Classified... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Exceptions. 1404.7003 Section 1404.7003 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL...

  7. 40 CFR 1517.4 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Exceptions. 1517.4 Section 1517.4 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY PUBLIC MEETING PROCEDURES OF THE COUNCIL ON...) Disclose investigative techniques and procedures, or, (vi) Endanger the life or physical safety of...

  8. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 3 2014-01-01 2014-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  9. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 3 2013-01-01 2013-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  10. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  11. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 3 2012-01-01 2012-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  12. Counseling with Mothers of Exceptional Children

    ERIC Educational Resources Information Center

    Kaplan, Bert L.

    1971-01-01

    It is possible for elementary school guidance counselors to help mothers of exceptional children face the severe reality demands they experience as internal turmoil marked by anger guilt and self depreciation. Once their feelings have been elicited and legitimized exploration of how feelings influence behavior toward children becomes possible.…

  13. 40 CFR 1517.4 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY PUBLIC MEETING PROCEDURES OF THE COUNCIL ON ENVIRONMENTAL QUALITY § 1517.4 Exceptions. (a) A meeting or portion thereof may be closed to public observation...) Disclose investigative techniques and procedures, or, (vi) Endanger the life or physical safety of...

  14. 45 CFR 671.5 - Exceptions

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Exceptions 671.5 Section 671.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE REGULATION Prohibited... pollutants or waste allowed under the Act to Prevent Marine Pollution from Ships (33 U.S.C. 1901 et seq.),...

  15. 45 CFR 671.5 - Exceptions

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Exceptions 671.5 Section 671.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE REGULATION Prohibited... pollutants or waste allowed under the Act to Prevent Marine Pollution from Ships (33 U.S.C. 1901 et seq.),...

  16. 45 CFR 671.5 - Exceptions

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Exceptions 671.5 Section 671.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE REGULATION Prohibited... pollutants or waste allowed under the Act to Prevent Marine Pollution from Ships (33 U.S.C. 1901 et seq.),...

  17. 45 CFR 671.5 - Exceptions

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Exceptions 671.5 Section 671.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE REGULATION Prohibited... pollutants or waste allowed under the Act to Prevent Marine Pollution from Ships (33 U.S.C. 1901 et seq.),...

  18. 45 CFR 671.5 - Exceptions

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Exceptions 671.5 Section 671.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION WASTE REGULATION Prohibited... pollutants or waste allowed under the Act to Prevent Marine Pollution from Ships (33 U.S.C. 1901 et seq.),...

  19. Fort Lewis Exceptional Family Member Program (EFMP)

    ERIC Educational Resources Information Center

    Hebdon, Heather

    2007-01-01

    Located in the shadow of Mt. Rainier, Fort Lewis is the home of the highest per capita exceptional family member population in the Army. Ideally located on the Northwest coast of Washington State, Fort Lewis is home to the Strykers and First Brigade. Combined with its close proximity to McChord Air Force Base, the installation is ideally suited to…

  20. Drug Therapy: Exceptional Child Bibliography Series.

    ERIC Educational Resources Information Center

    Council for Exceptional Children, Reston, VA. Information Center on Exceptional Children.

    The bibliography lists 31 items relating to drug therapy selected from "Exceptional Child Education Abstracts." One in a series of over 50 similar selected listings, the bibliography cites research reports, conference papers, journal articles, texts, and program guides. Each entry contains bibliographical data, availability information, indexing…

  1. Program for Exceptional Children: Regulations and Procedures.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta. Office of Instructional Services.

    The document reviews state of Georgia and federal law regarding the provision of special education programs for exceptional children and youth and outline procedures for providing those programs. Section I presents a summary of Georgia Chapter 32-6A, particularly the sections which address establishment of other special programs of education;…

  2. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  3. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  4. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 14 2013-01-01 2013-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  5. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  6. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 14 2011-01-01 2011-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  7. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  8. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  9. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  10. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  11. Administrative Manual: Programs for Exceptional Children.

    ERIC Educational Resources Information Center

    Delaware State Dept. of Public Instruction, Dover. Exceptional Children/Special Programs Div.

    This manual incorporates the Delaware State Board of Education's rules and regulations governing the education of exceptional children and is intended to provide guidance and information to educators, administrators, parents, and the public. The section on handicapped children covers the following areas: access to special education and related…

  12. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  13. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  14. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  15. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  16. 7 CFR 502.15 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Exceptions. 502.15 Section 502.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON BELTSVILLE AGRICULTURE RESEARCH CENTER PROPERTY, BELTSVILLE, MARYLAND §...

  17. 7 CFR 502.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Exceptions. 502.15 Section 502.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON BELTSVILLE AGRICULTURE RESEARCH CENTER PROPERTY, BELTSVILLE, MARYLAND §...

  18. 7 CFR 502.15 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Exceptions. 502.15 Section 502.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON BELTSVILLE AGRICULTURE RESEARCH CENTER PROPERTY, BELTSVILLE, MARYLAND §...

  19. 7 CFR 502.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 502.15 Section 502.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON BELTSVILLE AGRICULTURE RESEARCH CENTER PROPERTY, BELTSVILLE, MARYLAND §...

  20. 7 CFR 502.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 502.15 Section 502.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON BELTSVILLE AGRICULTURE RESEARCH CENTER PROPERTY, BELTSVILLE, MARYLAND §...

  1. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  2. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  3. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  4. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  5. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  6. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  7. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  8. 12 CFR 1022.74 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regarding Risk-Based Pricing § 1022.74 Exceptions. (a) Application for specific terms—(1) In general. A person is not required to provide a risk-based pricing notice to the consumer under § 1022.72(a) or (c... risk-based pricing notice to the consumer under § 1022.72(a), (c), or (d) if the person provides...

  9. 12 CFR 222.74 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REPORTING (REGULATION V) Duties of Users Regarding Risk-Based Pricing § 222.74 Exceptions. (a) Application for specific terms—(1) In general. A person is not required to provide a risk-based pricing notice to... action notice. A person is not required to provide a risk-based pricing notice to the consumer...

  10. 12 CFR 222.74 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) FAIR CREDIT REPORTING (REGULATION V) Duties of Users Regarding Risk-Based Pricing § 222.74 Exceptions... pricing notice to the consumer under § 222.72(a) or (c) if the consumer applies for specific material... requested credit. (b) Adverse action notice. A person is not required to provide a risk-based pricing...

  11. 48 CFR 217.7402 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7402 Exceptions. (a) The following undefinitized contract actions (UCAs) are not subject to... impracticable to adhere to the policy and procedures of this subpart for a particular contract action that...

  12. 48 CFR 217.7402 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7402 Exceptions. (a) The following undefinitized contract actions (UCAs) are not subject to... impracticable to adhere to the policy and procedures of this subpart for a particular contract action that...

  13. 48 CFR 217.7402 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7402 Exceptions. (a) The following undefinitized contract actions (UCAs) are not subject to... impracticable to adhere to the policy and procedures of this subpart for a particular contract action that...

  14. 48 CFR 217.7402 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7402 Exceptions. (a) The following undefinitized contract actions (UCAs) are not subject to... impracticable to adhere to the policy and procedures of this subpart for a particular contract action that...

  15. 48 CFR 217.7402 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7402 Exceptions. (a) The following undefinitized contract actions (UCAs) are not subject to... impracticable to adhere to the policy and procedures of this subpart for a particular contract action that...

  16. 48 CFR 825.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... documentation, to the Director, Office of Construction and Facilities Management, through the DSPE. (3) If the... FAR 25.104. The DSPE will decide whether to submit the material to the CAAC....

  17. 48 CFR 1425.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 1425.202 Exceptions. (a)(1) The CO may... the authority to make the determination that use of U.S. construction material would be impracticable... deemed approval for use of the cited foreign material. (3) For items not on the list at FAR...

  18. 48 CFR 1425.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 1425.202 Exceptions. (a)(1) The CO may... the authority to make the determination that use of U.S. construction material would be impracticable... deemed approval for use of the cited foreign material. (3) For items not on the list at FAR...

  19. 48 CFR 1425.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 1425.202 Exceptions. (a)(1) The CO may... the authority to make the determination that use of U.S. construction material would be impracticable... deemed approval for use of the cited foreign material. (3) For items not on the list at FAR...

  20. 48 CFR 225.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Construction Materials 225.202 Exceptions. (a)(2) A nonavailability determination is not required for construction materials listed in FAR 25.104(a... levels specified in 225.103(b)(ii). Use the estimated value of the construction materials to...

  1. 48 CFR 825.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... documentation, to the Director, Office of Construction and Facilities Management, through the DSPE. (3) If the... FAR 25.104. The DSPE will decide whether to submit the material to the CAAC....

  2. 48 CFR 825.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... documentation, to the Director, Office of Construction and Facilities Management, through the DSPE. (3) If the... FAR 25.104. The DSPE will decide whether to submit the material to the CAAC....

  3. 48 CFR 1425.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 1425.202 Exceptions. (a)(1) The CO may... the authority to make the determination that use of U.S. construction material would be impracticable... deemed approval for use of the cited foreign material. (3) For items not on the list at FAR...

  4. 48 CFR 25.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FOREIGN ACQUISITION Buy American-Construction Materials 25.202 Exceptions. (a) When one of the following... Buy American statute to a particular construction material would be impracticable or would be...) Nonavailability. The head of the contracting activity may determine that a particular construction material is...

  5. 48 CFR 25.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 25.202 Exceptions. (a) When one of the... construction materials without regard to the restrictions of the Buy American Act: (1) Impracticable or... the Buy American Act to a particular construction material would be impracticable or would...

  6. 48 CFR 825.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... documentation, to the Director, Office of Construction and Facilities Management, through the DSPE. (3) If the... FAR 25.104. The DSPE will decide whether to submit the material to the CAAC....

  7. 48 CFR 825.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... documentation, to the Director, Office of Construction and Facilities Management, through the DSPE. (3) If the... FAR 25.104. The DSPE will decide whether to submit the material to the CAAC....

  8. 48 CFR 25.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 25.202 Exceptions. (a) When one of the... construction materials without regard to the restrictions of the Buy American Act: (1) Impracticable or... the Buy American Act to a particular construction material would be impracticable or would...

  9. 48 CFR 25.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 25.202 Exceptions. (a) When one of the... construction materials without regard to the restrictions of the Buy American Act: (1) Impracticable or... the Buy American Act to a particular construction material would be impracticable or would...

  10. 48 CFR 225.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Construction Materials 225.202 Exceptions. (a)(2) A nonavailability determination is not required for construction materials listed in FAR 25.104(a... levels specified in 225.103(b)(ii). Use the estimated value of the construction materials to...

  11. 48 CFR 225.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 225.202 Exceptions. (a)(2) A nonavailability determination is not required for construction materials listed in FAR... the levels specified in 225.103(b)(ii). Use the estimated value of the construction materials...

  12. 48 CFR 1425.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 1425.202 Exceptions. (a)(1) The CO may... the authority to make the determination that use of U.S. construction material would be impracticable... deemed approval for use of the cited foreign material. (3) For items not on the list at FAR...

  13. 48 CFR 225.202 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 225.202 Exceptions. (a)(2) A nonavailability determination is not required for construction materials listed in FAR... the levels specified in 225.103(b)(ii). Use the estimated value of the construction materials...

  14. 48 CFR 225.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Construction Materials 225.202 Exceptions. (a)(2) A nonavailability determination is not required for construction materials listed in FAR 25.104(a... levels specified in 225.103(b)(ii). Use the estimated value of the construction materials to...

  15. 48 CFR 25.202 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOREIGN ACQUISITION Buy American Act-Construction Materials 25.202 Exceptions. (a) When one of the... construction materials without regard to the restrictions of the Buy American Act: (1) Impracticable or... the Buy American Act to a particular construction material would be impracticable or would...

  16. 14 CFR 1203.409 - Exceptional cases.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Exceptional cases. 1203.409 Section 1203.409 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM... Information Security Program Committee, Security Division, Washington, DC 20546 for a...

  17. 14 CFR 1203.409 - Exceptional cases.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Exceptional cases. 1203.409 Section 1203.409 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for... Security Program Committee, Security Division, Washington, DC 20546 for a classification determination....

  18. 14 CFR 1203.409 - Exceptional cases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Exceptional cases. 1203.409 Section 1203.409 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM... Information Security Program Committee, Security Division, Washington, DC 20546 for a...

  19. 14 CFR 1203.409 - Exceptional cases.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Exceptional cases. 1203.409 Section 1203.409 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM... Information Security Program Committee, Security Division, Washington, DC 20546 for a...

  20. Early Childhood Intervention-Exceptionalities: A Selective Bibliography. Exceptional Child Bibliography Series No. 669.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Handicapped and Gifted Children, Reston, VA.

    The annotated bibliography on early childhood intervention-exceptionalities contains approximately 150 abstracts and associated indexing information for documents published from 1968 to 1974 and selected from the computer files of the Council for Exceptional Children's Information Services and the Education Resources Information Center (ERIC). It…

  1. 77 FR 20614 - Petition Requesting Exception from Lead Content Limits; Notice Granting Exception

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... the issues raised by the petition. In the Federal Register of November 16, 2011 (76 FR 70975), we..., 2012 (77 FR 478), we reopened the comment period for 30 days, with comments due on February 6, 2012. We... COMMISSION Petition Requesting Exception from Lead Content Limits; Notice Granting Exception AGENCY:...

  2. Habitat Suitability Index Models: Common carp

    USGS Publications Warehouse

    Edwards, Elizabeth A.; Twomey, Katie

    1982-01-01

    The common carp (Cyprinus carpio) is a native of Asia. It is now found on every continent except Antarctica (Jester 1974) and in all 48 contiguous States (Sigler 1958). The northern limit to carp distribution appears to be the 18° C isotherm (Keleher 1956). The common carp hybridizes in nature with the goldfish (Carassius auratus) (Bardach et al. 1972; Smith 1979).

  3. Space Science IS Accessible to Students with Exceptional Needs: Results from Exceptional Needs Workshops

    NASA Astrophysics Data System (ADS)

    Runyon, C. J.; Merritt, M.; Guimond, K.

    2003-12-01

    The majority of students with disabilities in the US are required to achieve the same academic levels as their non-impaired peers. Unfortunately, there are few specialized materials to help these exceptional students. To assist students in meeting their goals, SERCH, a NASA Office of Space Science Broker/Facilitator, has been working with NASA education product developers and educators from informal and formal settings to identify what kinds of materials they need and what mediums will work best. As a result of both direct classrooms observations and hands-on workshops we have begun generating adaptive lessons plans that meet the national standards for Science, Technology, Engineering and Mathematics. During the workshops, participants simulate various disabilities (e.g., hearing, vision, orthopedic impairments, learning difficulties) while working through Space Science activities and discuss necessary adaptations/modifications in real-time. For example, we modified the Solar System Distance activity first designed by ASU to include the use of larger beads or pom-poms instead of the suggested small plastic beads. This simple adaptation permits students with orthopedic impairments to more readily take part in the lesson and to actively "observe" the distance between the planets. Examples of this activity and more will be illustrated. In addition to making modifications and suggestions for adaptations, workshop participants shared many simple recommendations that can help ALL learners participate more readily in classroom activities and discussions. Among these are: (1) Use simple, sans-serif fonts and high contrast presentation media (e.g., white text on black is most effective); (2) Repetition and use of multiple presentation modes is very helpful. (3) Actively involve the learner, and (4) Keep things simple to begin with, then work toward the more complex - think of the audience, the ultimate user.

  4. Exceptional Complex Chromosomal Rearrangements in Three Generations

    PubMed Central

    Kartapradja, Hannie; Marzuki, Nanis Sacharina; Pertile, Mark D.; Francis, David; Suciati, Lita Putri; Anggaratri, Helena Woro; Ambarwati, Debby Dwi; Idris, Firman Prathama; Lesmana, Harry; Trimarsanto, Hidayat; Paramayuda, Chrysantine; Harahap, Alida Roswita

    2015-01-01

    We report an exceptional complex chromosomal rearrangement (CCR) found in three individuals in a family that involves 4 chromosomes with 5 breakpoints. The CCR was ascertained in a phenotypically abnormal newborn with additional chromosomal material on the short arm of chromosome 4. Maternal karyotyping indicated that the mother carried an apparently balanced CCR involving chromosomes 4, 6, 11, and 18. Maternal transmission of the derivative chromosome 4 resulted in partial trisomy for chromosomes 6q and 18q and a partial monosomy of chromosome 4p in the proband. Further family studies found that the maternal grandmother carried the same apparently balanced CCR as the proband's mother, which was confirmed using the whole chromosome painting (WCP) FISH. High resolution whole genome microarray analysis of DNA from the proband's mother found no evidence for copy number imbalance in the vicinity of the CCR translocation breakpoints, or elsewhere in the genome, providing evidence that the mother's and grandmother's CCRs were balanced at a molecular level. This structural rearrangement can be categorized as an exceptional CCR due to its complexity and is a rare example of an exceptional CCR being transmitted in balanced and/or unbalanced form across three generations. PMID:25722897

  5. Asymptotic dynamics of the exceptional Bianchi cosmologies

    NASA Astrophysics Data System (ADS)

    Hewitt, C. G.; Horwood, J. T.; Wainwright, J.

    2003-05-01

    In this paper we give, for the first time, a qualitative description of the asymptotic dynamics of a class of non-tilted spatially homogeneous (SH) cosmologies, the so-called exceptional Bianchi cosmologies, which are of Bianchi type VI$_{-1/9}$. This class is of interest for two reasons. Firstly, it is generic within the class of non-tilted SH cosmologies, being of the same generality as the models of Bianchi types VIII and IX. Secondly, it is the SH limit of a generic class of spatially inhomogeneous $G_{2}$ cosmologies. Using the orthonormal frame formalism and Hubble-normalized variables, we show that the exceptional Bianchi cosmologies differ from the non-exceptional Bianchi cosmologies of type VI$_{h}$ in two significant ways. Firstly, the models exhibit an oscillatory approach to the initial singularity and hence are not asymptotically self-similar. Secondly, at late times, although the models are asymptotically self-similar, the future attractor for the vacuum-dominated models is the so-called Robinson-Trautman SH model instead of the vacuum SH plane wave models.

  6. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  7. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  8. 24 CFR 401.411 - Guidelines for determining exception rents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... narrative explanation of special need. (b) How are exception rents calculated? (1) Exception rents must be... approve an exception rent greater than 120 percent of Fair Market Rent, based on a narrative...

  9. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  10. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  11. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  12. Common Variable Immunodeficiency.

    PubMed

    Saikia, Biman; Gupta, Sudhir

    2016-04-01

    Common variable immunodeficiency (CVID) is the most common primary immunodeficiency of young adolescents and adults which also affects the children. The disease remains largely under-diagnosed in India and Southeast Asian countries. Although in majority of cases it is sporadic, disease may be inherited in a autosomal recessive pattern and rarely, in autosomal dominant pattern. Patients, in addition to frequent sino-pulmonary infections, are also susceptible to various autoimmune diseases and malignancy, predominantly lymphoma and leukemia. Other characteristic lesions include lymphocytic and granulomatous interstitial lung disease, and nodular lymphoid hyperplasia of gut. Diagnosis requires reduced levels of at least two immunoglobulin isotypes: IgG with IgA and/or IgM and impaired specific antibody response to vaccines. A number of gene mutations have been described in CVID; however, these genetic alterations account for less than 20% of cases of CVID. Flow cytometry aptly demonstrates a disturbed B cell homeostasis with reduced or absent memory B cells and increased CD21(low) B cells and transitional B cell populations. Approximately one-third of patients with CVID also display T cell functional defects. Immunoglobulin therapy remains the mainstay of treatment. Immunologists and other clinicians in India and other South East Asian countries need to be aware of CVID so that early diagnosis can be made, as currently, majority of these patients still go undiagnosed. PMID:26868026

  13. Exceptional Fireball Activity of Orionids in 2006

    NASA Astrophysics Data System (ADS)

    Spurný, Pavel; Shrbený, Lukáš

    2008-06-01

    We report exceptional fireball activity of the Orionid meteor shower in 2006. During four nights in October 2006 the autonomous fireball observatories of the Czech part of the European Fireball Network (EN) recorded 48 fireballs belonging to the Orionids. This is significantly more than the total number of Orionids recorded during about five decades long continuous operation of the EN. Based on precise multi-station photographic and radiometric data we present accurate atmospheric trajectories, heliocentric orbits, light curves and basic physical properties of 10 Orionid fireballs with atmospheric trajectories that were long enough and, with one exception, were observed from at least three stations. Seven were recorded in within a 2-h interval in the night of 20/21 October. Their basic parameters such as radiant positions and heliocentric orbits are very similar. This high fireball activity originated from a very compact geocentric radiant defined by α = 95.10° ± 0.10° and δ = 15.50° ± 0.06°. These fireballs most likely belonged to a distinct filament of larger meteoroids trapped in 1:5 resonance with Jupiter. From detailed light curves and basic fireball classification we found that these meteoroids appertain to the weakest component of interplanetary matter.

  14. 'Historicising common sense'.

    PubMed

    Millstone, Noah

    2012-12-01

    This essay is an expanded set of comments on the social psychology papers written for the special issue on History and Social Psychology. It considers what social psychology, and particularly the theory of social representations, might offer historians working on similar problems, and what historical methods might offer social psychology. The social history of thinking has been a major theme in twentieth and twenty-first century historical writing, represented most recently by the genre of 'cultural history'. Cultural history and the theory of social representations have common ancestors in early twentieth-century social science. Nevertheless, the two lines of research have developed in different ways and are better seen as complementary than similar. The theory of social representations usefully foregrounds issues, like social division and change over time, that cultural history relegates to the background. But for historians, the theory of social representations seems oddly fixated on comparing the thought styles associated with positivist science and 'common sense'. Using historical analysis, this essay tries to dissect the core opposition 'science : common sense' and argues for a more flexible approach to comparing modes of thought.

  15. Common HEP UNIX Environment

    NASA Astrophysics Data System (ADS)

    Taddei, Arnaud

    After it had been decided to design a common user environment for UNIX platforms among HEP laboratories, a joint project between DESY and CERN had been started. The project consists in 2 phases: 1. Provide a common user environment at shell level, 2. Provide a common user environment at graphical level (X11). Phase 1 is in production at DESY and at CERN as well as at PISA and RAL. It has been developed around the scripts originally designed at DESY Zeuthen improved and extended with a 2 months project at CERN with a contribution from DESY Hamburg. It consists of a set of files which are customizing the environment for the 6 main shells (sh, csh, ksh, bash, tcsh, zsh) on the main platforms (AIX, HP-UX, IRIX, SunOS, Solaris 2, OSF/1, ULTRIX, etc.) and it is divided at several "sociological" levels: HEP, site, machine, cluster, group of users and user with some levels which are optional. The second phase is under design and a first proposal has been published. A first version of the phase 2 exists already for AIX and Solaris, and it should be available for all other platforms, by the time of the conference. This is a major collective work between several HEP laboratories involved in the HEPiX-scripts and HEPiX-X11 working-groups.

  16. Exceptionally preserved jellyfishes from the Middle Cambrian.

    PubMed

    Cartwright, Paulyn; Halgedahl, Susan L; Hendricks, Jonathan R; Jarrard, Richard D; Marques, Antonio C; Collins, Allen G; Lieberman, Bruce S

    2007-10-31

    Cnidarians represent an early diverging animal group and thus insight into their origin and diversification is key to understanding metazoan evolution. Further, cnidarian jellyfish comprise an important component of modern marine planktonic ecosystems. Here we report on exceptionally preserved cnidarian jellyfish fossils from the Middle Cambrian (approximately 505 million years old) Marjum Formation of Utah. These are the first described Cambrian jellyfish fossils to display exquisite preservation of soft part anatomy including detailed features of structures interpreted as trailing tentacles and subumbrellar and exumbrellar surfaces. If the interpretation of these preserved characters is correct, their presence is diagnostic of modern jellyfish taxa. These new discoveries may provide insight into the scope of cnidarian diversity shortly after the Cambrian radiation, and would reinforce the notion that important taxonomic components of the modern planktonic realm were in place by the Cambrian period.

  17. Bronchial haemangioma: exceptionally rare cause of haemoptysis.

    PubMed

    Jennings, Scott; Tharion, John; Jones, Peter; Brown, Michael

    2013-12-01

    Bronchial haemangioma is an exceptionally rare cause of haemoptysis in the adult. There are currently less than 10 recorded cases in the literature. Airway haemangiomas are generally seen in infants with coexistent cutaneous haemangiomas. The incidence of bronchial haemangioma in adults remains unknown. This case reports the diagnosis and treatment of a bronchial haemangioma in a 56 year-old male presenting with a one-month history of haemoptysis. Bronchial haemangioma diagnosis was confirmed and excision performed by bronchoscopy without complication. Bronchial haemangioma should be a considered differential diagnosis in the presence of meaningful haemoptysis when an endoluminal lesion is visualised on computed tomography scan. This case also demonstrates that bronchial haemangiomas can be successfully removed via bronchoscopy with minimal risk and discomfort to the patient.

  18. Exceptionally elevated triglyceride in severe lipemia retinalis

    PubMed Central

    Yin, Han Y; Warman, Roberto; Suh, Edward H; Cheng, Anny MS

    2016-01-01

    Purpose To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG). Design Observational case report. Observations A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation. Results Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months. Conclusion Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. PMID:27799830

  19. Exceptionally preserved jellyfishes from the Middle Cambrian.

    PubMed

    Cartwright, Paulyn; Halgedahl, Susan L; Hendricks, Jonathan R; Jarrard, Richard D; Marques, Antonio C; Collins, Allen G; Lieberman, Bruce S

    2007-01-01

    Cnidarians represent an early diverging animal group and thus insight into their origin and diversification is key to understanding metazoan evolution. Further, cnidarian jellyfish comprise an important component of modern marine planktonic ecosystems. Here we report on exceptionally preserved cnidarian jellyfish fossils from the Middle Cambrian (approximately 505 million years old) Marjum Formation of Utah. These are the first described Cambrian jellyfish fossils to display exquisite preservation of soft part anatomy including detailed features of structures interpreted as trailing tentacles and subumbrellar and exumbrellar surfaces. If the interpretation of these preserved characters is correct, their presence is diagnostic of modern jellyfish taxa. These new discoveries may provide insight into the scope of cnidarian diversity shortly after the Cambrian radiation, and would reinforce the notion that important taxonomic components of the modern planktonic realm were in place by the Cambrian period. PMID:17971881

  20. Exceptional field theory: SO(5,5)

    NASA Astrophysics Data System (ADS)

    Abzalov, Aidar; Bakhmatov, Ilya; Musaev, Edvard T.

    2015-06-01

    We construct Exceptional Field Theory for the group SO(5, 5) based on the extended (6+16)-dimensional spacetime, which after reduction gives the maximal D = 6 supergravity. We present both a true action and a duality-invariant pseudo-action formulations. All the fields of the theory depend on the complete extended spacetime. The U-duality group SO(5, 5) is made a geometric symmetry of the theory by virtue of introducing the generalised Lie derivative that incorporates a duality transformation. Tensor hierarchy appears as a natural consequence of the algebra of generalised Lie derivatives that are viewed as gauge transformations. Upon truncating different subsets of the extra coordinates, maximal supergravities in D = 11 and D = 10 (type IIB) can be recovered from this theory.

  1. The PVC superphylum: exceptions to the bacterial definition?

    PubMed

    Fuerst, John A

    2013-10-01

    The PVC superphylum is a grouping of distinct phyla of the domain bacteria proposed initially on the basis of 16S rRNA gene sequence analysis. It consists of a core of phyla Planctomycetes, Verrucomicrobia and Chlamydiae, but several other phyla have been considered to be members, including phylum Lentisphaerae and several other phyla consisting only of yet-to-be cultured members. The genomics-based links between Planctomycetes, Verrucomicrobia and Chlamydiae have been recently strengthened, but there appear to be other features which may confirm the relationship at least of Planctomycetes, Verrucomicrobia and Lentisphaerae. Remarkably these include the unique planctomycetal compartmentalized cell plan differing from the cell organization typical for bacteria. Such a shared cell plan suggests that the common ancestor of the PVC superphylum members may also have been compartmentalized, suggesting this is an evolutionarily homologous feature at least within the superphylum. Both the PVC endomembranes and the eukaryote-homologous membrane-coating MC proteins linked to endocytosis ability in Gemmata obscuriglobus and shared by PVC members suggest such homology may extend beyond the bacteria to the Eukarya. If so, either our definition of bacteria may have to change or PVC members admitted to be exceptions. The cases for and against considering the PVC superphylum members as exceptions to the bacteria are discussed, and arguments for them as exceptions presented. Recent critical analysis has favoured convergence and analogy for explaining eukaryote-like features in planctomycetes and other PVC organisms. The case is made for constructing hypotheses leaving the possibility of homology and evolutionary links to eukaryote features open. As the case of discovery of endocytosis-like protein uptake in planctomycetes has suggested, this may prove a strong basis for the immediate future of experimental research programs in the PVC scientific community.

  2. "i" Before "e" Except after----what??

    ERIC Educational Resources Information Center

    Donlan, Dan

    1986-01-01

    Discusses the enigma of what and how people know apparently trivial information. Presents an experiment, expected answers, and actual responses to grammar questions to determine the degree of common knowledge in professional trivia. Concludes that further research may bring a clearer understanding of the "tradition" of language teaching and offers…

  3. 45 CFR 160.204 - Process for requesting exception determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Process for requesting exception determinations... Process for requesting exception determinations. (a) A request to except a provision of State law from..., requirement, or implementation specification for which the exception is requested; (3) The part of...

  4. 45 CFR 160.204 - Process for requesting exception determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Process for requesting exception determinations... Process for requesting exception determinations. (a) A request to except a provision of State law from..., requirement, or implementation specification for which the exception is requested; (3) The part of...

  5. 45 CFR 160.204 - Process for requesting exception determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Process for requesting exception determinations... Process for requesting exception determinations. (a) A request to except a provision of State law from..., requirement, or implementation specification for which the exception is requested; (3) The part of...

  6. How Common is Common Use Facilities at Airports

    NASA Astrophysics Data System (ADS)

    Barbeau, Addison D.

    This study looked at common use airports across the country and at the implementation of common use facailities at airports. Common use consists of several elements that maybe installed at an airport. One of the elements is the self-service kiosks that allow passengers to have a faster check-in process, therefore moving them more quickly within the airport. Another element is signage and the incorporation of each airline's logo. Another aspect of common useis an airport regaining control of terminal gates by reducing the number of gates that are exclusively leased to a specific air carrier. This research focused on the current state of the common use facilities across the United States and examines the advantages and disadvantages of this approach. The research entailed interviews with personnel at a wide range of airports and found that each airport is in a different stage of implementation; some have fully implemented the common use concept while others are in the beginning stages of implementation. The questions were tailored to determine what the advantages and disadvantages are of a common use facility. The most common advantages reported included flexibility and cost. In the commom use system the airport reserves the right to move any airline to a different gate at any time for any reason. In turn, this helps reduce gates delays at that facility. For the airports that were interviewed no major disadvantages were reported. One down side of common use facilities for the airport involved is the major capital cost that is required to move to a common use system.

  7. The record of time in cratonic interior strata: Does exceptionally slow subsidence necessarily result in exceptionally poor stratigraphic completeness?

    USGS Publications Warehouse

    Runkel, Anthony C.; Miller, J.F.; McKay, R.M.; Palmer, A.R.; Taylor, John F.

    2008-01-01

    A newly constructed a high-resolution chronostratigraphic and lithostratigraphic framework for the Upper Cambrian and Lower Ordovician Sauk Sequence in the cratonic interior of North America provides insight into the long-standing question of how time is recorded in sedimentary packages deposited in shallow epeiric seas across regions with exceptionally slow subsidence. It reveals that time is recorded in these strata in a manner fundamentally similar to the way it is in a number of nearshore marine-dominated sedimentary packages that were deposited under conditions of markedly higher subsidence rates. The principal consequence of slow subsidence in the cratonic interior appears largely to be a pronounced shingling of chronostratigraphic units perpendicular to depositional strike. An evaluation of relative stratigraphic completeness of the Upper Cambrian and Lower Ordovician of this region suggests that a number of routine interpretations and assumptions must be re-evaluated. Our results are inconsistent with the common interpretation that: (1) cratonic interior sedimentary packages are exceptionally stratigraphically incomplete; and (2) that conditions of very slow subsidence and a bathymetrically shallow shelf by themselves preclude deposition of a relatively complete record of time. In refuting these conventional assumptions, our conclusions have implications for a variety of approaches that require a fundamental understanding of the stratigraphic record of time, such as efforts to construct eustatic sea level curves and evaluations of the fossil record of evolution.

  8. 78 FR 4883 - Excepted Service; Consolidated Listing of Schedules A, B, and C Exceptions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... published as regulations in the Federal Register (FR) and the Code of Federal Regulations (CFR). Excepted... applicability prescribed by the Federal Register Act for regulations published in either the FR or the CFR... Reconstruction. These positions provide for the independent and objective conduct and supervision of audits...

  9. American Indian Exceptional Children and Youth. An ERIC Exceptional Child Education Report.

    ERIC Educational Resources Information Center

    Johnson, Marilyn J., Ed.; Ramirez, Bruce A., Ed.

    The document contains summaries of papers and ensuing discussions presented at a 1985 symposium on exceptional American Indian children and youth. The opening address (by Beverly Valley, a parent and school board member) stresses the role of parents and the need for less culturally biased testing. Two papers deal with parent and family…

  10. Une Exception Francaise: Les Grandes Ecoles (A French Exception: The Great Schools).

    ERIC Educational Resources Information Center

    Kimmel, Alain

    1996-01-01

    Examines the role of exceptional schools in France that have produced famous personages such as Charles de Gaulle and Jean-Paul Sartre. The schools reviewed include L'Ecole Nationale d'Administration, L'Ecole Polytechnique, L'Ecole Normale Superieure, L'Ecole des Hautes Etudes Commerciales, Saint-Cyr, and L'Institut d'Etudes Politiques de Paris.…

  11. Common Cause Failure Modeling

    NASA Technical Reports Server (NTRS)

    Hark, Frank; Britton, Paul; Ring, Robert; Novack, Steven

    2015-01-01

    Space Launch System (SLS) Agenda: Objective; Key Definitions; Calculating Common Cause; Examples; Defense against Common Cause; Impact of varied Common Cause Failure (CCF) and abortability; Response Surface for various CCF Beta; Takeaways.

  12. 14 CFR Appendix B to Part 43 - Recording of Major Repairs and Major Alterations

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Alterations B Appendix B to Part 43 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT MAINTENANCE, PREVENTIVE MAINTENANCE, REBUILDING, AND ALTERATION Pt. 43, App. B Appendix B to Part 43—Recording of Major Repairs and Major Alterations (a) Except as provided in paragraphs...

  13. 75 FR 80747 - End-User Exception to Mandatory Clearing of Swaps

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... exception'').\\6\\ \\5\\ See Process for Review of Swaps for Mandatory Clearing, 75 FR 67277 (Nov. 2, 2010). \\6... December 21, 2010. \\8\\ See Swap Data Recordkeeping and Reporting Requirements, 75 FR 76573, December 8... Practices at 20 (identifying master cross-netting and cross-guarantee structures as common credit...

  14. Working with Adults with Exceptional Needs: A Guide for the Trainer.

    ERIC Educational Resources Information Center

    Carlisle, Lynn, Comp.; Connelly, Trudy, Comp.

    This guide, written for persons who conduct training sessions, workshops or other meetings attended by adults with exceptional needs, begins with a brief outline of the characteristics of adult learners. A list of 10 true-false statements is then presented to assess knowledge of disabling conditions and some common myths surrounding society's…

  15. 50 CFR 14.64 - Exceptions to export declaration requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and fishery products exported for purposes of human or animal consumption or taken in waters under the... taxonomic information, and must declare the country of origin. Except: That this exception will not apply...

  16. NIH exceptional responders to cancer therapy study launched

    Cancer.gov

    The Exceptional Responders Initiative, a study to investigate the molecular factors of tumors associated with exceptional treatment responses of cancer patients to drug therapies, was launched today by NCI. Scientists will attempt to identify the molecula

  17. 15 CFR 740.2 - Restrictions on all License Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Exception. Editorial Note: For Federal Register citations affecting § 740.2, see the List of CFR Sections... sanctioned destination (Cuba, Iran, North Korea, and Syria), unless a license exception or portion thereof...

  18. Implant fractures: Rare but not exceptional.

    PubMed

    Sanivarapu, Sahitya; Moogla, Srinivas; Kuntcham, Rupa Sruthi; Kolaparthy, Lakshmi Kanth

    2016-01-01

    Fabrication of dentures aided with implants has become a preferred treatment option for rehabilitation of completely and partially edentulous patients when durability is concerned. Simulation to natural teeth in terms of esthetics and to a greater extent in function can be considered as key elements in the raise of implant dentistry worldwide. Despite its high success rate, therapy with osseointegrated dental implants is not free of complications. Implant failure can occur for other reasons, with implant fracture being one of the major reasons for late failure. Although the incidence of implant fractures may be low, it invariably effects the patient and also clinician. Thus, sound evidence based knowledge of cause of fracture is mandatory for that careful treatment that can reduce the incidence of fracture helping in a better treatment plan. The aim of this review is to enlighten the various causes of implant fracture. PMID:27041830

  19. Implant fractures: Rare but not exceptional

    PubMed Central

    Sanivarapu, Sahitya; Moogla, Srinivas; Kuntcham, Rupa Sruthi; Kolaparthy, Lakshmi Kanth

    2016-01-01

    Fabrication of dentures aided with implants has become a preferred treatment option for rehabilitation of completely and partially edentulous patients when durability is concerned. Simulation to natural teeth in terms of esthetics and to a greater extent in function can be considered as key elements in the raise of implant dentistry worldwide. Despite its high success rate, therapy with osseointegrated dental implants is not free of complications. Implant failure can occur for other reasons, with implant fracture being one of the major reasons for late failure. Although the incidence of implant fractures may be low, it invariably effects the patient and also clinician. Thus, sound evidence based knowledge of cause of fracture is mandatory for that careful treatment that can reduce the incidence of fracture helping in a better treatment plan. The aim of this review is to enlighten the various causes of implant fracture. PMID:27041830

  20. 12 CFR 367.19 - Exceptions to suspensions and exclusions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Exceptions to suspensions and exclusions. (a) Exceptions to the effects of suspensions and exclusions may be..., the Ethics Counselor may except such a contracting action from the effects of suspension and/or exclusion upon a determination, in writing, that a compelling reason exists for utilization of...

  1. 43 CFR 12.720 - Excepted articles, materials, and supplies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... excepted articles, materials, and supplies in FAR 25.108 (48 CFR 25.108). ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Excepted articles, materials, and supplies... Assistance Programs Buy American Act-Supplies § 12.720 Excepted articles, materials, and supplies. (a)...

  2. 43 CFR 12.720 - Excepted articles, materials, and supplies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... excepted articles, materials, and supplies in FAR 25.108 (48 CFR 25.108). ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Excepted articles, materials, and supplies... Assistance Programs Buy American Act-Supplies § 12.720 Excepted articles, materials, and supplies. (a)...

  3. 43 CFR 12.720 - Excepted articles, materials, and supplies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... excepted articles, materials, and supplies in FAR 25.108 (48 CFR 25.108). ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Excepted articles, materials, and supplies... Assistance Programs Buy American Act-Supplies § 12.720 Excepted articles, materials, and supplies. (a)...

  4. 43 CFR 12.720 - Excepted articles, materials, and supplies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... excepted articles, materials, and supplies in FAR 25.108 (48 CFR 25.108). ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Excepted articles, materials, and supplies... Assistance Programs Buy American Act-Supplies § 12.720 Excepted articles, materials, and supplies. (a)...

  5. 43 CFR 12.720 - Excepted articles, materials, and supplies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... excepted articles, materials, and supplies in FAR 25.108 (48 CFR 25.108). ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Excepted articles, materials, and supplies... Assistance Programs Buy American Act-Supplies § 12.720 Excepted articles, materials, and supplies. (a)...

  6. 10 CFR 835.606 - Exceptions to labeling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Exceptions to labeling requirements. 835.606 Section 835.606 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Posting and Labeling § 835.606 Exceptions to labeling requirements. (a) Items and containers may be excepted from the radioactive material labeling requirements of § 835.605 when:...

  7. 21 CFR 1307.03 - Exceptions to regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... discretion, but in no case shall he/she be required to grant an exception to any person which is otherwise required by law or the regulations cited in this section. Special Exceptions for Manufacture and... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exceptions to regulations. 1307.03 Section...

  8. 47 CFR 1.277 - Exceptions; oral arguments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Exceptions; oral arguments. 1.277 Section 1.277... Proceedings § 1.277 Exceptions; oral arguments. (a) The consolidated supporting brief and exceptions to the... filed, any party may request oral argument not later than five days after the time for filing replies...

  9. 47 CFR 1.277 - Exceptions; oral arguments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Exceptions; oral arguments. 1.277 Section 1.277... Proceedings § 1.277 Exceptions; oral arguments. (a) The consolidated supporting brief and exceptions to the... filed, any party may request oral argument not later than five days after the time for filing replies...

  10. 47 CFR 1.277 - Exceptions; oral arguments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Exceptions; oral arguments. 1.277 Section 1.277... Proceedings § 1.277 Exceptions; oral arguments. (a) The consolidated supporting brief and exceptions to the... filed, any party may request oral argument not later than five days after the time for filing replies...

  11. 47 CFR 1.277 - Exceptions; oral arguments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Exceptions; oral arguments. 1.277 Section 1.277... Proceedings § 1.277 Exceptions; oral arguments. (a) The consolidated supporting brief and exceptions to the... filed, any party may request oral argument not later than five days after the time for filing replies...

  12. 10 CFR 835.604 - Exceptions to posting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Exceptions to posting requirements. 835.604 Section 835.604 Energy DEPARTMENT OF ENERGY OCCUPATIONAL RADIATION PROTECTION Posting and Labeling § 835.604 Exceptions to posting requirements. (a) Areas may be excepted from the posting requirements of § 835.603 for periods of less than 8 continuous hours...

  13. 47 CFR 1.277 - Exceptions; oral arguments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Exceptions; oral arguments. 1.277 Section 1.277... Proceedings § 1.277 Exceptions; oral arguments. (a) The consolidated supporting brief and exceptions to the... filed, any party may request oral argument not later than five days after the time for filing replies...

  14. 40 CFR 761.219 - One-year exception reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 32 2013-07-01 2013-07-01 false One-year exception reporting. 761.219... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.219 One-year exception reporting. (a) A disposer of PCB waste shall submit a One-year Exception Report to the EPA Regional Administrator for the Region...

  15. 40 CFR 761.219 - One-year exception reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false One-year exception reporting. 761.219... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.219 One-year exception reporting. (a) A disposer of PCB waste shall submit a One-year Exception Report to the EPA Regional Administrator for the Region...

  16. 49 CFR 604.12 - Reporting requirements for all exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CHARTER SERVICE Exceptions § 604.12 Reporting requirements for all exceptions. (a) A recipient that provides charter service in accordance with one or more of the exceptions... period of at least three years from the date of the service or lease. A recipient may maintain...

  17. 49 CFR 604.12 - Reporting requirements for all exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CHARTER SERVICE Exceptions § 604.12 Reporting requirements for all exceptions. (a) A recipient that provides charter service in accordance with one or more of the exceptions... period of at least three years from the date of the service or lease. A recipient may maintain...

  18. 19 CFR 134.33 - J-List exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false J-List exceptions. 134.33 Section 134.33 Customs... COUNTRY OF ORIGIN MARKING Exceptions to Marking Requirements § 134.33 J-List exceptions. Articles of a... with the provisions of section 304(a)(3)(J), Tariff Act of 1930, as amended (19 U.S.C....

  19. 15 CFR 740.2 - Restrictions on all License Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... EXCEPTIONS § 740.2 Restrictions on all License Exceptions. (a) You may not use any License Exception if any...) “Space qualified” items. Commodities defined in ECCNs 3A001.b.8 (Traveling Wave Tube Amplifiers (TWTAs... (Traveling Wave Tube Amplifiers (TWTAs) exceeding 18 GHz), 6A002.e, 6A008.j.1, or 6A998.b and...

  20. 15 CFR 740.2 - Restrictions on all License Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... EXCEPTIONS § 740.2 Restrictions on all License Exceptions. (a) You may not use any License Exception if any...) “Space qualified” items. Commodities defined in ECCNs 3A001.b.8 (Traveling Wave Tube Amplifiers (TWTAs... (Traveling Wave Tube Amplifiers (TWTAs) exceeding 18 GHz), 6A002.e, 6A008.j.1, or 6A998.b and...