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Sample records for exceptionally common major

  1. Exceptional longevity and exceptionally high metabolic rates in anthropoid primates are linked to a major modification of the ubiquinone reduction site of cytochrome b.

    PubMed

    Rottenberg, Hagai

    2014-10-01

    The maximal lifespan of Anthropoid primates (monkeys, apes and humans) exceed the lifespan of most other mammals of equal body mass. Unexpectedly, their exceptional longevity is associated with exceptionally high metabolic rates, in apparent contradiction to the Free Radical Theory of Aging. It was therefore suggested that in anthropoid primates (and several other taxa of mammals and birds) the mitochondrial electron transport complexes evolved to modify the relationship between basal electron transport and superoxide generation to allow for the evolution of exceptional longevity. Cytochrome b, the core protein of the bc1 complex is a major source of superoxide. The amino-acid sequence of cytochrome b evolved much faster in anthropoid than in prosimian primates, and most other mammals, resulting in a large change in the amino-acids composition of the protein. As a result of these changes cytochrome b in anthropoid primates is significantly less hydrophobic and contains more polar residues than other primates and most other mammals. Most of these changes are clustered around the reduction site of uboiquinone. In particular a key positively charged residue, arginine 313, that interacts with propionate D of heme bH, and thus raises its redox potential, is substituted in anthropoid primates with the neutral residue glutamine, most likely resulting in a lower redox potential of heme bH and faster reduction of ubiquinone at high proton motive force. It is suggested that these changes contribute to the observed increased rates of basal metabolism and reduce the rates of superoxide production, thus allowing for increased lifespan.

  2. Common Genetic Variants on 6q24 Associated With Exceptional Episodic Memory Performance in the Elderly

    PubMed Central

    Barral, Sandra; Cosentino, Stephanie; Christensen, Kaare; Newman, Anne B.; Perls, Thomas T.; Province, Michael A.; Mayeux, Richard

    2015-01-01

    IMPORTANCE There aregenetic influences on memory ability as we age. but no specific genes have been identified. OBJECTIVE To use a cognitive endophenotype. exceptional episodic memory(EEM) performance. derived from nondemented offspring from the Long Life FamilyStudy(LLFS) to identify genetic variants that may be responsible for the high cognitive performance of LLFS participants and further replicate these variants using an additional 4006 nondemented individuals from 4 independent elderly cohorts DESIGN, SETTING, AND PARTICIPANTS A total of 467 LLFS participants from 18 families with 2 or more offspring that exhibited exceptional memory performance were used for genome-wide linkage analysis Adjusted multivariate linear analyses in the 40-megabase region encompassing the linkage peak were conducted using 4 independent replication data sets that included 4006 nondemented elderly individuals. Results of the individual replication cohorts were combined by meta-analysis MAIN OUTCOME MEASURE Episodic memory scores computed as the mean of the 2 standardized measures of Logical Memory IA and IIA RESULTS Heritability estimates indicated a significant genetic component for E EM (h2 = 0.21; SE = 0.09) Genome-wide linkage analysis revealed that EEM was linked to the 6q24 region (maximum logarithm of odds score, 3.64) Association analysis in LLFS families identified single-nucleotide polymorphisms (SNPs) nominally associated with EEM in the 40-megabase window encompassing the linkage peak Replication in one cohort identified a set of 26 SNPs associated with episodic memory (P ≤ 05) Meta-analysis of the 26 SNPs using the 4 independent replication cohorts found SN Ps rs9321334 and rs6902875 to be nominally significantly associated with episodic memory (P= .009 and P = .013. respectively). With meta-analysis restricted to individuals lacking an APOE ε4 allele. SNP rs6902875 became statistically significant (meta-analysis. P = 6.7 × 10−5) Haplotypeanalysis incorporating the

  3. A major Pseudomonas aeruginosa clone common to patients and aquatic habitats.

    PubMed Central

    Römling, U; Wingender, J; Müller, H; Tümmler, B

    1994-01-01

    The genomic relatedness of 573 Pseudomonas aeruginosa strains from environmental and clinical habitats was examined by digesting the genome with the rare-cutting enzyme SpeI. Thirty-nine strains were collected from environmental habitats mainly of aquatic origin, like rivers, lakes, or sanitary facilities. Four hundred fifty strains were collected from 76 patients with cystic fibrosis (CF) treated at four different centers, and 25 additional clinical isolates were collected from patients suffering from other diseases. Twenty-nine P. aeruginosa isolates were collected from the environment of one CF clinic. Thirty strains from culture collections were of environmental and clinic origin. A common macrorestriction fingerprint pattern was found in 13 of 46 CF patients, 5 of 29 environmental isolates from the same hospital, in a single ear infection isolate from another hospital, and 8 of 38 isolates from aquatic habitats about 300 km away from the CF clinic. The data indicate that closely related variants of one major clone (called clone C) persisted in various spatially and temporally separated habitats. Southern analysis of the clonal variants with six gene probes and two probes for genes coding for rRNA revealed almost the same hybridization patterns. With the exception of the phenotypically rapidly evolving CF isolates, the close relatedness of the strains of the clone was also shown by their identical responses in pyocin typing, phage typing, and serotyping. Besides clone C, three other P. aeruginosa clones were isolated from more than one clinical or environmental source. Images PMID:8031075

  4. Exceptionally preserved North American Paleogene metatherians: adaptations and discovery of a major gap in the opossum fossil record.

    PubMed

    Sánchez-Villagra, Marcelo; Ladevèze, Sandrine; Horovitz, Inés; Argot, Christine; Hooker, Jeremy J; Macrini, Thomas E; Martin, Thomas; Moore-Fay, Scott; de Muizon, Christian; Schmelzle, Thomas; Asher, Robert J

    2007-06-22

    A major gap in our knowledge of the evolution of marsupial mammals concerns the Paleogene of the northern continents, a critical time and place to link the early history of metatherians in Asia and North America with the more recent diversification in South America and Australia. We studied new exceptionally well-preserved partial skeletons of the Early Oligocene fossil Herpetotherium from the White River Formation in Wyoming, which allowed us to test the relationships of this taxon and examine its adaptations. Herpetotheriidae, with a fossil record extending from the Cretaceous to the Miocene, has traditionally been allied with opossums (Didelphidae) based on fragmentary material, mainly dentitions. Analysis of the new material reveals that several aspects of the cranial and postcranial anatomy, some of which suggests a terrestrial lifestyle, distinguish Herpetotherium from opossums. We found that Herpetotherium is the sister group to the crown group Marsupialia and is not a stem didelphid. Combination of the new palaeontological data with molecular divergence estimates, suggests the presence of a long undocumented gap in the fossil record of opossums extending some 45Myr from the Early Miocene to the Cretaceous.

  5. Common Genetic and Environmental Influences on Major Depressive Disorder and Conduct Disorder

    ERIC Educational Resources Information Center

    Subbarao, Anjali; Rhee, Soo Hyun; Young, Susan E.; Ehringer, Marissa A.; Corley, Robin P.; Hewitt, John K.

    2008-01-01

    The evidence for common genetic and environmental influences on conduct disorder (CD) and major depressive disorder (MDD) in adolescents was examined. A sample of 570 monozygotic twin pairs, 592 dizygotic twin pairs, and 426 non-twin siblings, aged 12-18 years, was recruited from the Colorado Twin Registry. For the past year data, there was a…

  6. Exceptional Students: Exceptional Needs.

    ERIC Educational Resources Information Center

    Burt, Marilyn; And Others

    The purpose of this investigation was to determine the needs and problems of exceptional middle school students as well as their perceptions of guidance services. Participants in the study were 229 educable mentally-retarded (EMR) and 245 gifted (GIF) students in six Alachua County (Florida) middle schools. The racial distribution of the students…

  7. Exceptionally High Representation of Burkholderia cepacia among B. cepacia Complex Isolates Recovered from the Major Portuguese Cystic Fibrosis Center▿

    PubMed Central

    Cunha, Mónica V.; Pinto-de-Oliveira, Ana; Meirinhos-Soares, Luís; Salgado, Maria José; Melo-Cristino, José; Correia, Susana; Barreto, Celeste; Sá-Correia, Isabel

    2007-01-01

    Burkholderia cepacia, a species found infrequently in cystic fibrosis (CF), was isolated from 85% of patients infected with bacteria of the B. cepacia complex that visited the major Portuguese CF center, in Lisbon, during 2003 to 2005. A detailed molecular analysis revealed that this was mainly due to two B. cepacia clones. These clones were indistinguishable from two strains isolated from intrinsically contaminated nonsterile saline solutions for nasal application, detected during routine market surveillance by the Portuguese Medicines and Health Products Authority. PMID:17360834

  8. Exceptions to the rules of oil-spill behavior: Case studies of major oil spills of the past twenty years

    SciTech Connect

    Hayes, M.O.

    1994-11-01

    Studies of major oil spills over the past 20 yr have allowed an evolution of our understanding of how to respond to and remediate the environmental impacts from such spills. There have been a number of spills for which follow-up research has provided major turning points that allowed the development of certain rules of oil-spill behavior. For example, the spill of over 100,000 tons of crude oil by the tanker Urquiola on the coast of Spain in May 1976 demonstrated the importance of hydrodynamic energy level in natural cleanup processes. Research on the spill of over 200,000 tons of crude oil along the coast of France by the tanker Amoco Cadiz in March 1978 allowed a better understanding of the long-term effects of spilled oil on exposed tidal flats and salt marshes. The oil spilled by the tanker Exxon Valdez in Prince William Sound, Alaska, in March 1989 impacted many miles of gravel beaches, which were treated by a number of methods, including some innovative berm-relocation techniques. A thorough understanding of the coastal geomorphology and processes of the spill site was essential for the development of meaningful contingency and response plans. Research on the impacts of intertidal habitats of the coast of Saudi Arabia during the Gulf War spill of 1991 indicates that some previously held concepts on oil behavior and fate on shorelines must be revised. One of the best established rules of oil-spill behavior was that the depth of oil penetration on sand beaches and tidal flats increases with increasing sediment grain size. However, no such correlation was found on the Saudi Arabian coast, primarily due to the presence of secondary porosity (e.g., bubble sand, extensive burrows, and gypsum crystals). The oil penetrated to depths of tens of centimeters, even in fine sand, which has significantly slowed natural removal processes and weathering rates. These sediments remained heavily oiled with incipient asphalt pavements forming two years after the spill.

  9. Resilience to major life stressors is not as common as thought

    PubMed Central

    Infurna, Frank J.; Luthar, Suniya S.

    2015-01-01

    We attempted to replicate findings that “most people are resilient” following three events: spousal loss, divorce, and unemployment. We applied growth mixture models to the same longitudinal data set that has previously been used to assert that resilience is ubiquitous. When using identical model specifications as in prior studies, we found that resilient trajectories were most common, but the number of trajectories identified was different. When we relaxed the assumptions that (a) all classes have similar variability in levels of post-adversity adjustment and (b) there is no variability in changes within classes (as in prior studies), we found that a resilience class was least common. Methodologically, our results demonstrate how findings on trajectories of change following major life stressors vary substantially depending on statistical model specifications. Conceptually, they underscore the errors inherent in any categorical statements about “rates of resilience” among individuals confronted with major life stressors. Pragmatically, they underscore the dangers in recommending against prophylactic interventions -- based on one method of analyzing longitudinal data -- for individuals who have experienced major life stressors. PMID:26993272

  10. Common volatiles are major attractants for neonate larvae of the specialist flea beetle Altica koreana (Coleoptera: Chrysomelidae)

    NASA Astrophysics Data System (ADS)

    Xue, Huai-Jun; Yang, Xing-Ke

    2008-07-01

    Olfactory stimuli play an important role in the host searching of larval phytophagous insects. Previous studies indicate that larvae that have to find feeding sites after hatching are generally attracted to host volatiles. However, there are few studies on the olfactory responses of neonate larvae to host volatiles in cases when those larvae hatched on the host plant. In the present study, we determined the olfactory responses of neonate larvae of the specialist flea beetle, Altica koreana Ogloblin, to host and six non-host plants, using a static-air “arena.” Larvae responded significantly to the host plant Potentilla chinensis Ser. and five of six non-host plants, compared to the control. Larvae did not prefer the host plant over the non-host plants (except Artemisia sp.) when offered a choice. Additionally, odours of a non-host plant, which were unattractive to neonate larvae, may have masked the attractive odour of the host plant. These results indicate that common volatiles can play a major role in attracting larvae of this specialist to plants, but attraction to such odours may not be the major mechanism of host choice.

  11. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders.

    PubMed

    Lotan, Amit; Fenckova, Michaela; Bralten, Janita; Alttoa, Aet; Dixson, Luanna; Williams, Robert W; van der Voet, Monique

    2014-01-01

    Major neuropsychiatric disorders are highly heritable, with mounting evidence suggesting that these disorders share overlapping sets of molecular and cellular underpinnings. In the current article we systematically test the degree of genetic commonality across six major neuropsychiatric disorders-attention deficit hyperactivity disorder (ADHD), anxiety disorders (Anx), autistic spectrum disorders (ASD), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). We curated a well-vetted list of genes based on large-scale human genetic studies based on the NHGRI catalog of published genome-wide association studies (GWAS). A total of 180 genes were accepted into the analysis on the basis of low but liberal GWAS p-values (<10(-5)). 22% of genes overlapped two or more disorders. The most widely shared subset of genes-common to five of six disorders-included ANK3, AS3MT, CACNA1C, CACNB2, CNNM2, CSMD1, DPCR1, ITIH3, NT5C2, PPP1R11, SYNE1, TCF4, TENM4, TRIM26, and ZNRD1. Using a suite of neuroinformatic resources, we showed that many of the shared genes are implicated in the postsynaptic density (PSD), expressed in immune tissues and co-expressed in developing human brain. Using a translational cross-species approach, we detected two distinct genetic components that were both shared by each of the six disorders; the 1st component is involved in CNS development, neural projections and synaptic transmission, while the 2nd is implicated in various cytoplasmic organelles and cellular processes. Combined, these genetic components account for 20-30% of the genetic load. The remaining risk is conferred by distinct, disorder-specific variants. Our systematic comparative analysis of shared and unique genetic factors highlights key gene sets and molecular processes that may ultimately translate into improved diagnosis and treatment of these debilitating disorders.

  12. Neuroinformatic analyses of common and distinct genetic components associated with major neuropsychiatric disorders

    PubMed Central

    Lotan, Amit; Fenckova, Michaela; Bralten, Janita; Alttoa, Aet; Dixson, Luanna; Williams, Robert W.; van der Voet, Monique

    2014-01-01

    Major neuropsychiatric disorders are highly heritable, with mounting evidence suggesting that these disorders share overlapping sets of molecular and cellular underpinnings. In the current article we systematically test the degree of genetic commonality across six major neuropsychiatric disorders—attention deficit hyperactivity disorder (ADHD), anxiety disorders (Anx), autistic spectrum disorders (ASD), bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). We curated a well-vetted list of genes based on large-scale human genetic studies based on the NHGRI catalog of published genome-wide association studies (GWAS). A total of 180 genes were accepted into the analysis on the basis of low but liberal GWAS p-values (<10−5). 22% of genes overlapped two or more disorders. The most widely shared subset of genes—common to five of six disorders–included ANK3, AS3MT, CACNA1C, CACNB2, CNNM2, CSMD1, DPCR1, ITIH3, NT5C2, PPP1R11, SYNE1, TCF4, TENM4, TRIM26, and ZNRD1. Using a suite of neuroinformatic resources, we showed that many of the shared genes are implicated in the postsynaptic density (PSD), expressed in immune tissues and co-expressed in developing human brain. Using a translational cross-species approach, we detected two distinct genetic components that were both shared by each of the six disorders; the 1st component is involved in CNS development, neural projections and synaptic transmission, while the 2nd is implicated in various cytoplasmic organelles and cellular processes. Combined, these genetic components account for 20–30% of the genetic load. The remaining risk is conferred by distinct, disorder-specific variants. Our systematic comparative analysis of shared and unique genetic factors highlights key gene sets and molecular processes that may ultimately translate into improved diagnosis and treatment of these debilitating disorders. PMID:25414627

  13. A Next Generation Air Monitor: Combining Orion and ISS Requirements for a Common Major Constituent Analyzer

    NASA Technical Reports Server (NTRS)

    Burchfield, David E.; Tissandier, Michael; Niu, William Hsein-Chi; Lewis, John F.

    2013-01-01

    The Major Constituent Analyzer (MCA) is a mass spectrometer-based instrument designed to provide critical monitoring of six major atmospheric constituents; nitrogen, oxygen, hydrogen, carbon dioxide, methane, and water vapor on-board the International Space Station. The analyzer has been an integral part of the Environmental Control and Life Support System (ECLSS) since the station went on-line. The Orion Air Monitor (OAM) was derived from the MCA and heavily optimized for reduced mass, lower power, faster water vapor response, and maintenance-free operation. The resulting OAM is approximately the size of the analyzer portion of the MCA, orbital-replacement unit 02 (ORU 02), while incorporating the functions of three other modules: Data Processing and Communication (ORU 01), Verification Gas Assembly (ORU 08), and Low Voltage Power Supply (ORU 04). The overlap in MCA and OAM requirements makes it possible to derive a common Air Monitor design that spans both applications while minimally impacting the weight and power limits imposed by the Multipurpose Crew Vehicle (MPCV). Benefits to ISS include the retirement of ORUs 01, 04, and 08, reducing up-mass and eliminating EEE parts obsolescence issues through the extended ISS mission phases. Benefits to MPCV and future deployed habitats under the Constellation program include greater interchangeability across ECLSS subsystems. This paper discusses the results of the requirements development study, where a superset of ISS and Orion air monitoring requirements were distilled; evaluated against increases in OAM functionality, mass, and power; and traded-off where possible using simple operating mode modifications. A system architecture and preliminary design addressing the common requirements will be presented.

  14. Outsourcing of common industry data within a major oil and gas exploration company

    SciTech Connect

    Hude, C.G. ); Glover, S. )

    1993-09-01

    Enhancing user productivity while reducing internal costs through improved accessibility and virtual elimination of data and software maintenance were the initial goals of this project. We achieved these objectives through the outsourcing of common well and production data with a major vendor. In this paper, we outline the changing internal business operations of a major oil company and its associated vendor relationship. The goals of this project were multifold: provide our users with real-time access to nationwide well and production data, eliminate data and system software maintenance and support, redeploy computer system resources and personnel for use elsewhere within the organization, and continue to provide users with the same level of service at less cost. We established a satisfactory interface between the users and the vendor database by employing existing technology. A mainframe-to-mainframe connection was established by installing a leased line between the two host sites. This allowed both companies to use existing network facilities with minimal modifications to each operating environment. This project was begun successfully in a relatively short time. Due to the success of this project, we are evaluating adding company proprietary data. However, because technology and requirements change, relational delivery of the data within a workstation/server environment can be addressed within this framework.

  15. Abnormal functional brain asymmetry in depression: evidence of biologic commonality between major depression and dysthymia.

    PubMed

    Bruder, Gerard E; Stewart, Jonathan W; Hellerstein, David; Alvarenga, Jorge E; Alschuler, Daniel; McGrath, Patrick J

    2012-04-30

    Prior studies have found abnormalities of functional brain asymmetry in patients having a major depressive disorder (MDD). This study aimed to replicate findings of reduced right hemisphere advantage for perceiving dichotic complex tones in depressed patients, and to determine whether patients having "pure" dysthymia show the same abnormality of perceptual asymmetry as MDD. It also examined gender differences in lateralization, and the extent to which abnormalities of perceptual asymmetry in depressed patients are dependent on gender. Unmedicated patients having either a MDD (n=96) or "pure" dysthymic disorder (n=42) and healthy controls (n=114) were tested on dichotic fused-words and complex-tone tests. Patient and control groups differed in right hemisphere advantage for complex tones, but not left hemisphere advantage for words. Reduced right hemisphere advantage for tones was equally present in MDD and dysthymia, but was more evident among depressed men than depressed women. Also, healthy men had greater hemispheric asymmetry than healthy women for both words and tones, whereas this gender difference was not seen for depressed patients. Dysthymia and MDD share a common abnormality of hemispheric asymmetry for dichotic listening.

  16. "We Are in This Together": Common Group Identity Predicts Majority Members' Active Acculturation Efforts to Integrate Immigrants.

    PubMed

    Kunst, Jonas R; Thomsen, Lotte; Sam, David L; Berry, John W

    2015-10-01

    Although integration involves a process of mutual accommodation, the role of majority groups is often downplayed to passive tolerance, leaving immigrants with the sole responsibility for active integration. However, we show that common group identity can actively involve majority members in this process across five studies. Study 1 showed that common identity positively predicted support of integration efforts; Studies 2 and 3 extended these findings, showing that it also predicted real behavior such as monetary donations and volunteering. A decrease in modern racism mediated the relations across these studies, and Studies 4 and 5 further demonstrated that it indeed mediated these effects over and above acculturation expectations and color-blindness, which somewhat compromised integration efforts. Moreover, the last two studies also demonstrated that common, but not dual, groups motivated integration efforts. Common identity appears crucial for securing majorities' altruistic efforts to integrate immigrants and, thus, for achieving functional multiculturalism.

  17. Commonality.

    ERIC Educational Resources Information Center

    Beaton, Albert E., Jr.

    Commonality analysis is an attempt to understand the relative predictive power of the regressor variables, both individually and in combination. The squared multiple correlation is broken up into elements assigned to each individual regressor and to each possible combination of regressors. The elements have the property that the appropriate sums…

  18. Common genetic variants, acting additively, are a major source of risk for autism

    PubMed Central

    2012-01-01

    Background Autism spectrum disorders (ASD) are early onset neurodevelopmental syndromes typified by impairments in reciprocal social interaction and communication, accompanied by restricted and repetitive behaviors. While rare and especially de novo genetic variation are known to affect liability, whether common genetic polymorphism plays a substantial role is an open question and the relative contribution of genes and environment is contentious. It is probable that the relative contributions of rare and common variation, as well as environment, differs between ASD families having only a single affected individual (simplex) versus multiplex families who have two or more affected individuals. Methods By using quantitative genetics techniques and the contrast of ASD subjects to controls, we estimate what portion of liability can be explained by additive genetic effects, known as narrow-sense heritability. We evaluate relatives of ASD subjects using the same methods to evaluate the assumptions of the additive model and partition families by simplex/multiplex status to determine how heritability changes with status. Results By analyzing common variation throughout the genome, we show that common genetic polymorphism exerts substantial additive genetic effects on ASD liability and that simplex/multiplex family status has an impact on the identified composition of that risk. As a fraction of the total variation in liability, the estimated narrow-sense heritability exceeds 60% for ASD individuals from multiplex families and is approximately 40% for simplex families. By analyzing parents, unaffected siblings and alleles not transmitted from parents to their affected children, we conclude that the data for simplex ASD families follow the expectation for additive models closely. The data from multiplex families deviate somewhat from an additive model, possibly due to parental assortative mating. Conclusions Our results, when viewed in the context of results from genome

  19. The Major Field Test in Business: A Direct Measure of Learning in Common Business Disciplines

    ERIC Educational Resources Information Center

    Simmons, Susan A.; Jones, Wesley M., Jr; Bolt, Cynthia E.

    2015-01-01

    Assurance of learning and its assessment are critical focal points in collegiate schools of business as programs strive to achieve or maintain Association to Advance Collegiate Schools of Business accreditation. Prior research suggests that student learning in business core disciplines can be measured by the Educational Testing Service Major Field…

  20. No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.

    PubMed

    Lynch, J M; Tate, S K; Kinirons, P; Weale, M E; Cavalleri, G L; Depondt, C; Murphy, K; O'Rourke, D; Doherty, C P; Shianna, K V; Wood, N W; Sander, J W; Delanty, N; Goldstein, D B; Sisodiya, S M

    2009-01-01

    Levetiracetam (LEV), a newer antiepileptic drug (AED) useful for several epilepsy syndromes, binds to SV2A. Identifying genetic variants that influence response to LEV may allow more tailored use of LEV. Obvious candidate genes are SV2A, SV2B and SV2C, which encode the only known binding site, synaptic vesicle protein 2 (SV2), with LEV binding to the SV2A isoform. SV2A is an essential protein as homozygous SV2A knockout mice appear normal at birth but fail to grow, experience severe seizures and die by 3 weeks. We addressed characterising AED response issues in pharmacogenetics and whether variation in these genes associates with response to LEV in two independent cohorts with epilepsy. We also investigated whether variation in these three genes associated with epilepsy predisposition in two larger cohorts of patients with various epilepsy phenotypes. Common genetic variation in SV2A, encoding the actual binding site of LEV, was fully represented in this study whereas SV2B and SV2C were not fully covered. None of the polymorphisms tested in SV2A, SV2B or SV2C influence LEV response or predisposition to epilepsy. We found no association between genetic variation in SV2A, SV2B or SV2C and response to LEV or epilepsy predisposition. We suggest this study design may be used in future pharmacogenetic work examining AED or LEV efficacy. However, different study designs would be needed to examine common variation with minor effect sizes, or rare variation, influencing AED or LEV response or epilepsy predisposition.

  1. Major Histocompatibility Complex Based Resistance to a Common Bacterial Pathogen of Amphibians

    PubMed Central

    Barribeau, Seth M.; Villinger, Jandouwe; Waldman, Bruce

    2008-01-01

    Given their well-developed systems of innate and adaptive immunity, global population declines of amphibians are particularly perplexing. To investigate the role of the major histocompatibilty complex (MHC) in conferring pathogen resistance, we challenged Xenopus laevis tadpoles bearing different combinations of four MHC haplotypes (f, g, j, and r) with the bacterial pathogen Aeromonas hydrophila in two experiments. In the first, we exposed ff, fg, gg, gj, and jj tadpoles, obtained from breeding MHC homozygous parents, to one of three doses of A. hydrophila or heat-killed bacteria as a control. In the second, we exposed ff, fg, fr, gg, rg, and rr tadpoles, obtained from breeding MHC heterozygous parents and subsequently genotyped by PCR, to A. hydrophila, heat-killed bacteria or media alone as controls. We thereby determined whether the same patterns of MHC resistance emerged within as among families, independent of non-MHC heritable differences. Tadpoles with r or g MHC haplotypes were more likely to die than were those with f or j haplotypes. Growth rates varied among MHC types, independent of exposure dose. Heterozygous individuals with both susceptible and resistant haplotypes were intermediate to either homozygous genotype in both size and survival. The effect of the MHC on growth and survival was consistent between experiments and across families. MHC alleles differentially confer resistance to, or tolerance of, the bacterial pathogen, which affects tadpoles' growth and survival. PMID:18629002

  2. Major histocompatibility complex based resistance to a common bacterial pathogen of amphibians.

    PubMed

    Barribeau, Seth M; Villinger, Jandouwe; Waldman, Bruce

    2008-07-16

    Given their well-developed systems of innate and adaptive immunity, global population declines of amphibians are particularly perplexing. To investigate the role of the major histocompatibility complex (MHC) in conferring pathogen resistance, we challenged Xenopus laevis tadpoles bearing different combinations of four MHC haplotypes (f, g, j, and r) with the bacterial pathogen Aeromonas hydrophila in two experiments. In the first, we exposed ff, fg, gg, gj, and jj tadpoles, obtained from breeding MHC homozygous parents, to one of three doses of A. hydrophila or heat-killed bacteria as a control. In the second, we exposed ff, fg, fr, gg, rg, and rr tadpoles, obtained from breeding MHC heterozygous parents and subsequently genotyped by PCR, to A. hydrophila, heat-killed bacteria or media alone as controls. We thereby determined whether the same patterns of MHC resistance emerged within as among families, independent of non-MHC heritable differences. Tadpoles with r or g MHC haplotypes were more likely to die than were those with f or j haplotypes. Growth rates varied among MHC types, independent of exposure dose. Heterozygous individuals with both susceptible and resistant haplotypes were intermediate to either homozygous genotype in both size and survival. The effect of the MHC on growth and survival was consistent between experiments and across families. MHC alleles differentially confer resistance to, or tolerance of, the bacterial pathogen, which affects tadpoles' growth and survival.

  3. Major histocompatibility complex variation in red wolves: evidence for common ancestry with coyotes and balancing selection.

    PubMed

    Hedrick, P W; Lee, R N; Garrigan, D

    2002-10-01

    We examined variation at a class II major histocompatibility complex (MHC) gene (DRB1) in the captive red wolf population and samples of coyotes from Texas and North Carolina. We found 4 alleles in the 48 red wolves, 8 alleles in the 10 coyotes from Texas and 15 alleles in the 29 coyotes from North Carolina. Two of the four alleles found in red wolves, Caru-2 and Caru-4, were found in both the Texas and North Carolina coyote samples. Allele Caru-1, previously found in gray wolves, was also found in the North Carolina sample. The most frequent red wolf allele, Caru-3, was not found in any of the coyote samples. However, an allele found in both the Texas and North Carolina coyote samples is only one nucleotide (one amino acid) different from this red wolf allele. Overall, it appears from examination of this MHC gene that red wolves are more closely related to coyotes than to gray wolves. There were a number of different types of evidence supporting the action of balancing selection in red wolves. Namely, there was: (i) an excess of heterozygotes compared with expectations; (ii) a higher rate of nonsynonymous than synonymous substitution for the functionally important antigen-binding site positions; (iii) an eight times higher average heterozygosity of individual amino acids at the positions identified as part of the antigen-binding site than those not associated with it; (iv) the amino acid divergence of four red wolf alleles was greater than that expected from a simulation of genetic drift; and (v) the distribution of alleles, and the distributions of amino acids at many positions were more even than expected from neutrality. Examination of the level and pattern of linkage disequilibria between pairs of sites suggest that the heterozygosity, substitution and frequencies at individual amino acids are not highly dependent upon each other.

  4. Exceptional Stars

    NASA Astrophysics Data System (ADS)

    Kulkarni, S. R.; Hansen, B.; van Kerkwijk, M.; Phinney, E. S.

    2005-12-01

    As part of our Interdisciplinary Scientist effort (PI, Kulkarni) for the Space Interferometry Mission (SIM) we proposed an investigation with SIM of a number of exceptional stars. With SIM we plan to observe dozens of nearby white dwarfs and search for planets surviving the evolution away from the main sequence as well as (newly formed) planets formed in the circumbinary disks of post-AGB binaries or as a result of white dwarf mergers. We propose to measure the proper motion of a sample of X-ray binaries and Be star binaries with the view of understanding the originof high latitude objects and inferring natal kicks and pre-supernova orbits. We plan to observe several compact object binaries to determine the mass of the compact star. Of particular importance is the proposed observation of SS 433 (for which we propose to use the spectrometer on SIM to measure the proper motion of the emission line clumps embedded in the relativistic jets). Separately we are investigating the issue of frame tie between SIM and the ecliptic frame (by observing binary millisecond pulsars with SIM; the position of these objects is very well determined by pulsar timing) and the degree to which highly precise visibility amplitude measurements can be inverted to infer binary parameters.

  5. Exceptional production of both prodigiosin and cycloprodigiosin as major metabolic constituents by a novel marine bacterium, Zooshikella rubidus S1-1.

    PubMed

    Lee, Jong Suk; Kim, Yong-Sook; Park, Sooyeon; Kim, Jihoon; Kang, So-Jung; Lee, Mi-Hwa; Ryu, Sangryeol; Choi, Jong Myoung; Oh, Tae-Kwang; Yoon, Jung-Hoon

    2011-07-01

    A Gram-negative, red-pigment-producing marine bacterial strain, designated S1-1, was isolated from the tidal flat sediment of the Yellow Sea, Korea. On the basis of phenotypic, phylogenetic, and genetic data, strain S1-1 (KCTC 11448BP) represented a new species of the genus Zooshikella. Thus, we propose the name Zooshikella rubidus sp. nov. Liquid chromatography and mass spectrometry of the red pigments produced by strain S1-1 revealed that the major metabolic compounds were prodigiosin and cycloprodigiosin. In addition, this organism produced six minor prodigiosin analogues, including two new structures that were previously unknown. To our knowledge, this is the first description of a microorganism that simultaneously produces prodigiosin and cycloprodigiosin as two major metabolites. Both prodigiosin and cycloprodigiosin showed antimicrobial activity against several microbial species. These bacteria were approximately 1.5-fold more sensitive to cycloprodigiosin than to prodigiosin. The metabolites also showed anticancer activity against human melanoma cells, which showed significantly more sensitivity to prodigiosin than to cycloprodigiosin. The secondary metabolite profiles of strain S1-1 and two reference bacterial strains were compared by liquid chromatography-mass spectrometry. Multivariate statistical analyses based on secondary metabolite profiles by liquid chromatography-mass spectrometry indicated that the metabolite profile of strain S1-1 could clearly be distinguished from those of two phylogenetically related, prodigiosin-producing bacterial strains.

  6. Exceptional Production of both Prodigiosin and Cycloprodigiosin as Major Metabolic Constituents by a Novel Marine Bacterium, Zooshikella rubidus S1-1 ▿ †

    PubMed Central

    Lee, Jong Suk; Kim, Yong-Sook; Park, Sooyeon; Kim, Jihoon; Kang, So-Jung; Lee, Mi-Hwa; Ryu, Sangryeol; Choi, Jong Myoung; Oh, Tae-Kwang; Yoon, Jung-Hoon

    2011-01-01

    A Gram-negative, red-pigment-producing marine bacterial strain, designated S1-1, was isolated from the tidal flat sediment of the Yellow Sea, Korea. On the basis of phenotypic, phylogenetic, and genetic data, strain S1-1 (KCTC 11448BP) represented a new species of the genus Zooshikella. Thus, we propose the name Zooshikella rubidus sp. nov. Liquid chromatography and mass spectrometry of the red pigments produced by strain S1-1 revealed that the major metabolic compounds were prodigiosin and cycloprodigiosin. In addition, this organism produced six minor prodigiosin analogues, including two new structures that were previously unknown. To our knowledge, this is the first description of a microorganism that simultaneously produces prodigiosin and cycloprodigiosin as two major metabolites. Both prodigiosin and cycloprodigiosin showed antimicrobial activity against several microbial species. These bacteria were approximately 1.5-fold more sensitive to cycloprodigiosin than to prodigiosin. The metabolites also showed anticancer activity against human melanoma cells, which showed significantly more sensitivity to prodigiosin than to cycloprodigiosin. The secondary metabolite profiles of strain S1-1 and two reference bacterial strains were compared by liquid chromatography-mass spectrometry. Multivariate statistical analyses based on secondary metabolite profiles by liquid chromatography-mass spectrometry indicated that the metabolite profile of strain S1-1 could clearly be distinguished from those of two phylogenetically related, prodigiosin-producing bacterial strains. PMID:21642414

  7. Exceptional Parent, 1993.

    ERIC Educational Resources Information Center

    Klein, Stanley D., Ed.

    1993-01-01

    This document consists of the nine issues of the journal "Exceptional Parent" published during 1993. This journal contains articles particularly aimed at parents of children with disabilities. Major articles published during this period are the following: "Annual Guide to Products and Services"; "Coping with Incontinence" (Katherine F. Jeter);…

  8. Expanding upon the 'extreme male brain' theory of autism as a common link between other major risk factors: a hypothesis.

    PubMed

    Wen, Wendy; Wen, Shi Wu

    2014-05-01

    On average, males have a stronger preference for physical systems and machines over interpersonal interactions; they have lower average levels of cognitive empathy or social cognition than females; and they have higher rates of 'extreme' intelligence when it comes to abstract concepts such as those found in mathematics and sciences. All three traits are also commonly associated with individuals with an autism spectrum disorder or ASD; clearly, it is not coincidental that incidence rates of autism are reportedly four times higher in males than in females. The common link between the majority of risk factors assessed in this review (including technological advancements, advanced parental age, socioeconomic status, and genetic predispositions towards ASDs in families of scientists and engineers) can be traced to a specific hormone, testosterone. It was established that traits which are typically associated with males are also typically associated with ASDs as well as individuals with antisocial personality disorder, or APD. The key distinction between individuals who are considered to be 'autistic' as opposed to those who are considered 'sociopathic' lies in the difference between their empathy deficits: whereas those who are 'autistic' are said to lack cognitive empathy (the ability to identify and understand the thoughts and feelings of others and to respond to these with appropriate emotions), those who are 'sociopathic' are said to lack emotional empathy (which is responsible for inhibiting acts of physical aggression or violence). This would explain why autistic individuals can have elevated testosterone levels without becoming physically aggressive.

  9. Identification, quantification, spatiotemporal distribution and genetic variation of major latex secondary metabolites in the common dandelion (Taraxacum officinale agg.).

    PubMed

    Huber, Meret; Triebwasser-Freese, Daniella; Reichelt, Michael; Heiling, Sven; Paetz, Christian; Chandran, Jima N; Bartram, Stefan; Schneider, Bernd; Gershenzon, Jonathan; Erb, Matthias

    2015-07-01

    The secondary metabolites in the roots, leaves and flowers of the common dandelion (Taraxacum officinale agg.) have been studied in detail. However, little is known about the specific constituents of the plant's highly specialized laticifer cells. Using a combination of liquid and gas chromatography, mass spectrometry and nuclear magnetic resonance spectrometry, we identified and quantified the major secondary metabolites in the latex of different organs across different growth stages in three genotypes, and tested the activity of the metabolites against the generalist root herbivore Diabrotica balteata. We found that common dandelion latex is dominated by three classes of secondary metabolites: phenolic inositol esters (PIEs), triterpene acetates (TritAc) and the sesquiterpene lactone taraxinic acid β-D-glucopyranosyl ester (TA-G). Purification and absolute quantification revealed concentrations in the upper mgg(-1) range for all compound classes with up to 6% PIEs, 5% TritAc and 7% TA-G per gram latex fresh weight. Contrary to typical secondary metabolite patterns, concentrations of all three classes increased with plant age. The highest concentrations were measured in the main root. PIE profiles differed both quantitatively and qualitatively between plant genotypes, whereas TritAc and TA-G differed only quantitatively. Metabolite concentrations were positively correlated within and between the different compound classes, indicating tight biosynthetic co-regulation. Latex metabolite extracts strongly repelled D. balteata larvae, suggesting that the latex constituents are biologically active.

  10. The majority of enteroaggregative Escherichia coli strains produce the E. coli common pilus when adhering to cultured epithelial cells.

    PubMed

    Avelino, Fabiola; Saldaña, Zeus; Islam, Sohidul; Monteiro-Neto, Valerio; Dall'Agnol, Monique; Eslava, Carlos A; Girón, Jorge A

    2010-11-01

    Enteroaggregative Escherichia coli (EAEC) have emerged as a significant worldwide cause of chronic diarrhea in the pediatric population and in HIV patients. The vast majority of EAEC strains do not produce the aggregative adherence fimbriae I-III (AAFs) so far reported and thus, what adherence factors are present in these strains remains unknown. Here, we investigated the prevalence of the chromosomal E. coli common pilus (ECP) genes and ECP production amongst 130 EAEC strains of diverse origin as well as the role of ECP in EAEC adherence. Through multiplex PCR analysis we found that 96% of EAEC strains contained the ecpA structural pilin gene whereas only 3.1% and 5.4% were positive for AAF fimbrial genes aggA or aafA, respectively. Among the ecpA(+) strains, 63% produced ECP when adhering to cultured epithelial cells. An ecpA mutant derived from prototypic strain 042 (AAF/II(+)) was not altered in adherence suggesting that the AAF/II, and not ECP, plays a major role in this strain. In contrast, strain 278-1 (AAF(-)) deleted of the ecpA gene was significantly reduced in adherence to cultured epithelial cells. In all, these data indicate a potential role of ECP in adherence for EAEC strains lacking the known AAFs and that in association with other adhesive determinants, ECP may contribute to their survival and persistence within the host and in the environment.

  11. A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans.

    PubMed

    Ngole-Jeme, Veronica M; Ekosse, Georges-Ivo E

    2015-07-31

    This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils.

  12. A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans

    PubMed Central

    Ngole-Jeme, Veronica M.; Ekosse, Georges-Ivo E.

    2015-01-01

    This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils. PMID:26264010

  13. Autophagy competes for a common phosphatidylethanolamine pool with major cellular PE-consuming pathways in Saccharomyces cerevisiae.

    PubMed

    Wilson-Zbinden, Caroline; dos Santos, Aline Xavier da Silveira; Stoffel-Studer, Ingrid; van der Vaart, Aniek; Hofmann, Kay; Reggiori, Fulvio; Riezman, Howard; Kraft, Claudine; Peter, Matthias

    2015-02-01

    Autophagy is a highly regulated pathway that selectively degrades cellular constituents such as protein aggregates and excessive or damaged organelles. This transport route is characterized by engulfment of the targeted cargo by autophagosomes. The formation of these double-membrane vesicles requires the covalent conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine (PE). However, the origin of PE and the regulation of lipid flux required for autophagy remain poorly understood. Using a genetic screen, we found that the temperature-sensitive growth and intracellular membrane organization defects of mcd4-174 and mcd4-P301L mutants are suppressed by deletion of essential autophagy genes such as ATG1 or ATG7. MCD4 encodes an ethanolamine phosphate transferase that uses PE as a precursor for an essential step in the synthesis of the glycosylphosphatidylinositol (GPI) anchor used to link a subset of plasma membrane proteins to lipid bilayers. Similar to the deletion of CHO2, a gene encoding the enzyme converting PE to phosphatidylcholine (PC), deletion of ATG7 was able to restore lipidation and plasma membrane localization of the GPI-anchored protein Gas1 and normal organization of intracellular membranes. Conversely, overexpression of Cho2 was lethal in mcd4-174 cells grown at restrictive temperature. Quantitative lipid analysis revealed that PE levels are substantially reduced in the mcd4-174 mutant but can be restored by deletion of ATG7 or CHO2. Taken together, these data suggest that autophagy competes for a common PE pool with major cellular PE-consuming pathways such as the GPI anchor and PC synthesis, highlighting the possible interplay between these pathways and the existence of signals that may coordinate PE flux.

  14. Simultaneous determination of major phytocannabinoids, their main metabolites, and common synthetic cannabinoids in urine samples by LC-MS/MS.

    PubMed

    Dong, Xiaoru; Li, Liliang; Ye, Yonghong; Zheng, Lixing; Jiang, Yan

    2016-10-15

    Simultaneous determination of major phytocannabinoids (THC, CBD, CBN), their main metabolites (11-OH-THC, THC-COOH, THC-COOH-glucuronide) and common synthetic cannabinoids (HU-210, JWH-018, JWH-073, JWH-250) remains an issue in forensic toxicology. The present study has developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to simultaneously detect the above 10 analytes in human urine samples. The chromatographic separation was performed on an ACQUITY UPLC(®)BEH Phenyl 1.7μm (2.1×100mm) column, using a mobile phase consisting of 0.1% formic acid in water and acetonitrile at a flow rate of 0.3mL/min in gradient elution mode. The limit of detection (LOD) and limit of quantification (LOQ) of all analytes were 0.01-0.5ng/mL and 0.05-1ng/mL, respectively. The assay was linear from LOQ to 100ng/mL for phytocannabinoids, their main metabolites and HU-210, and from 0.05 to 50ng/mL for JWH-250, JWH-018 and JWH-073. The extraction recoveries were over 50% and the matrix effects were between 59.4% and 100.1%. The accuracy and precision were <10.4% of bias and <10.5% of relative standard deviation (RSD), respectively. The developed method was applied to 5 urine samples from real caseworks, and the results that THC metabolites together with synthetic cannabinoids were detected demonstrated the effectiveness of our method.

  15. Bacterial components are the major contributors to the macrophage stimulating activity exhibited by extracts of common edible mushrooms

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Background: Recent studies have indicated that a major contributor to the innate immune enhancing properties of some medicinal plants is derived from the cell wall components of bacteria colonizing these plants. Purpose: The purpose of the current study was to assess if the bacteria present withi...

  16. Major correlates of mercury in small fish and common loons (Gavia immer) across four large study areas in Canada.

    PubMed

    Scheuhammer, A M; Lord, S I; Wayland, M; Burgess, N M; Champoux, L; Elliott, J E

    2016-03-01

    We investigated mercury (Hg) concentrations in small fish (mainly yellow perch, Perca flavescens; ∼60% of fish collected) and in blood of common loons (Gavia immer) that prey upon them during the breeding season on lakes in 4 large, widely separated study areas in Canada (>13 lakes per study area; total number of lakes = 93). Although surface sediments from lakes near a base metal smelter in Flin Flon, Manitoba had the highest Hg concentrations, perch and other small fish and blood of common loon chicks sampled from these same lakes had low Hg concentrations similar to those from uncontaminated reference lakes. Multiple regression modeling with AIC analysis indicated that lake pH was by far the most important single factor influencing perch Hg concentrations in lakes across the four study areas (R(2) = 0.29). The best model was a three-variable model (pH + alkalinity + sediment Se; Wi = 0.61, R(2) = 0.85). A single-variable model (fish Hg) best explained among-lake variability in loon chick blood Hg (Wi = 0.17; R(2) = 0.53). From a toxicological risk perspective, all lakes posing a potential Hg health risk for perch and possibly other small pelagic fish species (where mean fish muscle Hg concentrations exceeded 2.4 μg/g dry wt.), and for breeding common loons (where mean fish muscle Hg concentrations exceeded 0.8 μg/g dry wt., and loon chick blood Hg exceeded 1.4 μg/g dry wt.) had pH < 6.7 and were located in eastern Canada.

  17. Mosaic segmental uniparental isodisomy and progressive clonal selection: a common mechanism of late onset β-thalassemia major

    PubMed Central

    Harteveld, Cornelis L.; Refaldi, Chiara; Giambona, Antonino; Ruivenkamp, Claudia A. L.; Hoffer, Mariëtte J. V.; Pijpe, Jeroen; De Knijff, Peter; Borgna-Pignatti, Caterina; Maggio, Aurelio; Cappellini, Maria D.; Giordano, Piero C.

    2013-01-01

    Genomic DNA of 3 patients, born as healthy carriers and developing a late-onset severe transfusion-dependent beta-thalassemia major was studied by high-density genome wide SNP array analysis. A mosaic loss of heterozygosity for almost the entire 11p was found, not attributable to deletions but involving mosaicism for segmental paternal isodisomy of 11p. Mitotic recombination leading to mosaic segmental uniparental isodisomy on chromosome 11p in multiple tissues has been described as a molecular disease mechanism for a subset of sporadic Beckwith-Wiedemann syndrome cases. A similar mechanism also seems to be involved in causing late-onset disease in carriers of recessive mutations in other genes located in 11p, such as late-onset beta-thalassemia major and sickle cell disease. We suggest that the loss of maternally imprinted IGF-2 and H19 genes may account for the selective advantage of hematopoietic cells containing this segmental paternal isodisomy of 11p carrying the β-thalassemia mutation. PMID:22983591

  18. Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis

    PubMed Central

    Rao, Shuquan; Yao, Yao; Ryan, Joanne; Li, Tao; Wang, Duan; Zheng, Chuan; Xu, Yong; Xu, Qi

    2016-01-01

    Previous studies have investigated the association between common variants in FKBP5 and MDD; however, the results remain inconsistent. In order to conduct a comprehensive meta-analysis of the association between FKBP5 variants and MDD risk, seven studies involving 26582 subjects, including 12491 cases with MDD and 14091 controls, were enrolled totally. Four common SNPs (rs1360780, rs4713916, rs3800373 and rs755658) with complete data from two or more studies were analyzed. In the total sample, there was no evidence of a significant association between MDD and any of the four SNPs using a random-effects model. However, after removing one heterogeneous German study, as indicated by sensitivity analysis, both the rs1360780 T-allele (Z = 2.95, P = 0.003, OR = 1.06, 95% CI = 1.02–1.11) and the rs3800373 C-allele (Z = 3.05, P = 0.002, OR = 1.07, 95% CI 1.02–1.12) were significantly associated with MDD in a fixed-effect model. Our study thus provides support for an association between specific FKBP5 genetic variants and MDD risk. Rs4713916 was not significantly associated with MDD; However, this analysis had limited statistical power and larger sample sizes are required to further validate this result. Future research should also investigate possible gender- and ethnicity-specific differences in the association between FKBP5 and MDD. PMID:27601205

  19. Proton-dependent coniferin transport, a common major transport event in differentiating xylem tissue of woody plants.

    PubMed

    Tsuyama, Taku; Kawai, Ryo; Shitan, Nobukazu; Matoh, Toru; Sugiyama, Junji; Yoshinaga, Arata; Takabe, Keiji; Fujita, Minoru; Yazaki, Kazufumi

    2013-06-01

    Lignin biosynthesis is an essential physiological activity of vascular plants if they are to survive under various environmental stresses on land. The biosynthesis of lignin proceeds in the cell wall by polymerization of precursors; the initial step of lignin polymerization is the transportation of lignin monomers from the cytosol to the cell wall, which is critical for lignin formation. There has been much debate on the transported form of the lignin precursor, either as free monolignols or their glucosides. In this study, we performed biochemical analyses to characterize the membrane transport mechanism of lignin precursors using angiosperms, hybrid poplar (Populus sieboldii × Populus grandidentata) and poplar (Populus sieboldii), as well gymnosperms, Japanese cypress (Chamaecyparis obtusa) and pine (Pinus densiflora). Membrane vesicles prepared from differentiating xylem tissues showed clear ATP-dependent transport activity of coniferin, whereas less than 4% of the coniferin transport activity was seen for coniferyl alcohol. Bafilomycin A1 and proton gradient erasers markedly inhibited coniferin transport in hybrid poplar membrane vesicles; in contrast, vanadate had no effect. Cis-inhibition experiments suggested that this transport activity was specific for coniferin. Membrane fractionation of hybrid poplar microsomes demonstrated that transport activity was localized to the tonoplast- and endomembrane-rich fraction. Differentiating xylem of Japanese cypress exhibited almost identical transport properties, suggesting the involvement of a common endomembrane-associated proton/coniferin antiport mechanism in the lignifying tissues of woody plants, both angiosperms and gymnosperms.

  20. Use of a pig model to demonstrate vulnerability of major neck vessels to inflicted trauma from common household items.

    PubMed

    Byard, Roger W; Cains, Glenda E; Gilbert, John D

    2007-03-01

    Commonly available items including a ball point pen, a plastic knife, a broken wine bottle, and a broken wine glass were used to inflict stab and incised wounds to the necks of 3 previously euthanized Large White pigs. With relative ease, these items could be inserted into the necks of the pigs next to the jugular veins and carotid arteries. Despite precautions against the carrying of metal objects such as knives and nail files on board domestic and international flights, objects are still available within aircraft cabins that could be used to inflict serious and potentially life-threatening injuries. If airport and aircraft security measures are to be consistently applied, then consideration should be given to removing items such as glass bottles and glass drinking vessels. However, given the results of a relatively uncomplicated modification of a plastic knife, it may not be possible to remove all dangerous objects from aircraft. Security systems may therefore need to focus on measures such as increased surveillance of passenger behavior, rather than on attempting to eliminate every object that may serve as a potential weapon.

  1. Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder.

    PubMed

    Cutler, Jessica A; Rush, A John; McMahon, Francis J; Laje, Gonzalo

    2012-03-01

    The essential amino acid tryptophan is the precursor to serotonin, but it can also be metabolized into kynurenine through indoleamine-2,3-dioxygenase (IDO). Increased immune activation has long been associated with symptoms of depression and has been shown to upregulate the expression of IDO. The presence of additional IDO directs more tryptophan down the kynurenine pathway, leaving less available for synthesis of serotonin and its metabolites. Kynurenine can be metabolized through a series of enzymes to quinolinic acid, a potent N-methyl-D-aspartate receptor agonist with demonstrated neurotoxic effects. We tested the hypothesis that IDO plays a role in outcome of treatment with the selective serotonin reuptake inhibitor, citalopram. Patients consisted of 1953 participants enrolled in the Sequenced Treatment Alternatives to Relieve Depression study (STAR*D). Genotypes corresponding to 94 single nucleotide polymorphisms (SNPs) in the genes IDO1 and IDO2, which encode IDO and IDO2, were extracted from a larger genome-wide set and analyzed using single marker tests to look for association with previously defined response, remission and QIDS-C score change phenotypes, with adequate correction for racial stratification and multiple testing. One SNP, rs2929115, showed evidence of association with citalopram response (OR = 0.64, p = 0.0005) after experiment-wide correction for multiple testing. Another closely associated marker, rs2929116 (OR = 0.64, p = 0.0006) had an experiment-wide significant result. Both implicated SNPs are located between 26 kb and 28 kb downstream of IDO2. We conclude that common genetic variation in IDO1 and IDO2 may play a role in antidepressant treatment outcome. These results are modest in a genome-wide context and need to be replicated in an independent sample.

  2. SYNE1 ataxia is a common recessive ataxia with major non-cerebellar features: a large multi-centre study.

    PubMed

    Synofzik, Matthis; Smets, Katrien; Mallaret, Martial; Di Bella, Daniela; Gallenmüller, Constanze; Baets, Jonathan; Schulze, Martin; Magri, Stefania; Sarto, Elisa; Mustafa, Mona; Deconinck, Tine; Haack, Tobias; Züchner, Stephan; Gonzalez, Michael; Timmann, Dagmar; Stendel, Claudia; Klopstock, Thomas; Durr, Alexandra; Tranchant, Christine; Sturm, Marc; Hamza, Wahiba; Nanetti, Lorenzo; Mariotti, Caterina; Koenig, Michel; Schöls, Ludger; Schüle, Rebecca; de Jonghe, Peter; Anheim, Mathieu; Taroni, Franco; Bauer, Peter

    2016-05-01

    , including premature death due to respiratory dysfunction. With a relative frequency of ∼5%, SYNE1 is one of the more common recessive ataxias worldwide.

  3. Bacterial components are the major contributors to the macrophage stimulating activity exhibited by extracts of common edible mushrooms.

    PubMed

    Tyler, Heather L; Haron, Mona H; Pugh, Nirmal D; Zhang, Jin; Jackson, Colin R; Pasco, David S

    2016-10-12

    Recent studies have indicated that a major contributor to the innate immune enhancing properties of some medicinal plants is derived from the cell wall components of bacteria colonizing these plants. The purpose of the current study was to assess if the bacteria present within edible and medicinal mushrooms substantially contribute to the innate immune stimulating potential of these mushrooms. Whole mushrooms from thirteen types of edible fungi and individual parts from Agaricus bisporus were analyzed for in vitro macrophage activation as well as bacterial lipopolysaccharides (LPS) content, cell load, and community composition. Substantial variation between samples was observed in macrophage activation (over 500-fold), total bacterial load (over 200-fold), and LPS content (over 10 million-fold). Both LPS content (ρ = 0.832, p < 0.0001) and total bacterial load (ρ = 0.701, p < 0.0001) correlated significantly with macrophage activation in the whole mushroom extracts. Extract activity was negated by treatment with NaOH, conditions that inactivate LPS and other bacterial components. Significant correlations between macrophage activation and total bacterial load (ρ = 0.723, p = 0.0001) and LPS content (ρ = 0.951, p < 0.0001) were also observed between different tissues of Agaricus bisporus. Pseudomonas and Flavobacterium were the most prevalent genera identified in the different tissue parts and these taxa were significantly correlated with in vitro macrophage activation (ρ = 0.697, p < 0.0001 and ρ = 0.659, p = 0.0001, respectively). These results indicate that components derived from mushroom associated bacteria contribute substantially to the innate immune enhancing activity exhibited by mushrooms and may result in similar therapeutic actions as reported for ingestion of bacterial preparations such as probiotics.

  4. Exceptionality in vowel harmony

    NASA Astrophysics Data System (ADS)

    Szeredi, Daniel

    Vowel harmony has been of great interest in phonological research. It has been widely accepted that vowel harmony is a phonetically natural phenomenon, which means that it is a common pattern because it provides advantages to the speaker in articulation and to the listener in perception. Exceptional patterns proved to be a challenge to the phonetically grounded analysis as they, by their nature, introduce phonetically disadvantageous sequences to the surface form, that consist of harmonically different vowels. Such forms are found, for example in the Finnish stem tuoli 'chair' or in the Hungarian suffixed form hi:d-hoz 'to the bridge', both word forms containing a mix of front and back vowels. There has recently been evidence shown that there might be a phonetic level explanation for some exceptional patterns, as the possibility that some vowels participating in irregular stems (like the vowel [i] in the Hungarian stem hi:d 'bridge' above) differ in some small phonetic detail from vowels in regular stems. The main question has not been raised, though: does this phonetic detail matter for speakers? Would they use these minor differences when they have to categorize a new word as regular or irregular? A different recent trend in explaining morphophonological exceptionality by looking at the phonotactic regularities characteristic of classes of stems based on their morphological behavior. Studies have shown that speakers are aware of these regularities, and use them as cues when they have to decide what class a novel stem belongs to. These sublexical phonotactic regularities have already been shown to be present in some exceptional patterns vowel harmony, but many questions remain open: how is learning the static generalization linked to learning the allomorph selection facet of vowel harmony? How much does the effect of consonants on vowel harmony matter, when compared to the effect of vowel-to-vowel correspondences? This dissertation aims to test these two ideas

  5. Exceptional Responders Initial Feasibility Results

    Cancer.gov

    A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical

  6. Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.

    PubMed

    Wang, Jen C; Hinrichs, Anthony L; Stock, Heather; Budde, John; Allen, Rebecca; Bertelsen, Sarah; Kwon, Jennifer M; Wu, William; Dick, Danielle M; Rice, John; Jones, Kevin; Nurnberger, John I; Tischfield, Jay; Porjesz, Bernice; Edenberg, Howard J; Hesselbrock, Victor; Crowe, Ray; Schuckit, Mark; Begleiter, Henri; Reich, Theodore; Goate, Alison M; Bierut, Laura J

    2004-09-01

    Several correlated phenotypes, alcohol dependence, major depressive syndrome, and an endophenotype of electrophysiological measurements, event-related oscillations (EROs), have demonstrated linkage on the long arm of chromosome 7. Recently, we reported both linkage and association between polymorphisms in the gene encoding the muscarinic acetylcholine receptor M2 (CHRM2) and EROs. In this study, we evaluated whether genetic variation in the CHRM2 gene is also a risk factor for the correlated clinical characteristics of alcoholism and depression. The CHRM2 gene contains a single coding exon and a large 5' untranslated region encoded by multiple exons that can be alternatively spliced. Families were recruited through an alcohol dependent proband, and multiplex pedigrees were selected for genetic analyses. We examined 11 single nucleotide polymorphisms (SNPs) spanning the CHRM2 gene in these families. Using the UNPHASED pedigree disequilibrium test (PDTPHASE), three SNPs (one in intron 4 and two in intron 5) showed highly significant association with alcoholism (P=0.004-0.007). Two SNPs (both in intron 4) were significantly associated with major depressive syndrome (P=0.004 and 0.017). Haplotype analyses revealed that the most common haplotype (>40% frequency), T-T-T (rs1824024-rs2061174-rs324650), was under-transmitted to affected individuals with alcohol dependence and major depressive syndrome. Different complementary haplotypes were over-transmitted in alcohol dependent and depressed individuals. These findings provide strong evidence that variants within or close to the CHRM2 locus influence risk for two common psychiatric disorders.

  7. Analysis of Major Histocompatibility Complex-Bound HIV Peptides Identified from Various Cell Types Reveals Common Nested Peptides and Novel T Cell Responses

    PubMed Central

    Rucevic, Marijana; Kourjian, Georgio; Boucau, Julie; Blatnik, Renata; Garcia Bertran, Wilfredo; Berberich, Matthew J.; Walker, Bruce D.; Riemer, Angelika B.

    2016-01-01

    ABSTRACT Despite the critical role of epitope presentation for immune recognition, we still lack a comprehensive definition of HIV peptides presented by HIV-infected cells. Here we identified 107 major histocompatibility complex (MHC)-bound HIV peptides directly from the surface of live HIV-transfected 293T cells, HIV-infected B cells, and primary CD4 T cells expressing a variety of HLAs. The majority of peptides were 8 to 12 amino acids (aa) long and mostly derived from Gag and Pol. The analysis of the total MHC-peptidome and of HLA-A02-bound peptides identified new noncanonical HIV peptides of up to 16 aa that could not be predicted by HLA anchor scanning and revealed an heterogeneous surface peptidome. Nested sets of surface HIV peptides included optimal and extended HIV epitopes and peptides partly overlapping or distinct from known epitopes, revealing new immune responses in HIV-infected persons. Surprisingly, in all three cell types, a majority of Gag peptides derived from p15 rather than from the most immunogenic p24. The cytosolic degradation of peptide precursors in corresponding cells confirmed the generation of identified surface-nested peptides. Cytosolic degradation revealed peptides commonly produced in all cell types and displayed by various HLAs, peptides commonly produced in all cell types and selectively displayed by specific HLAs, and peptides produced in only one cell type. Importantly, we identified areas of proteins leading to common presentations of noncanonical peptides by several cell types with distinct HLAs. These peptides may benefit the design of immunogens, focusing T cell responses on relevant markers of HIV infection in the context of HLA diversity. IMPORTANCE The recognition of HIV-infected cells by immune T cells relies on the presentation of HIV-derived peptides by diverse HLA molecules at the surface of cells. The landscape of HIV peptides displayed by HIV-infected cells is not well defined. Considering the diversity of HLA

  8. Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis.

    PubMed

    Wise, T; Radua, J; Via, E; Cardoner, N; Abe, O; Adams, T M; Amico, F; Cheng, Y; Cole, J H; de Azevedo Marques Périco, C; Dickstein, D P; Farrow, T F D; Frodl, T; Wagner, G; Gotlib, I H; Gruber, O; Ham, B J; Job, D E; Kempton, M J; Kim, M J; Koolschijn, P C M P; Malhi, G S; Mataix-Cols, D; McIntosh, A M; Nugent, A C; O'Brien, J T; Pezzoli, S; Phillips, M L; Sachdev, P S; Salvadore, G; Selvaraj, S; Stanfield, A C; Thomas, A J; van Tol, M J; van der Wee, N J A; Veltman, D J; Young, A H; Fu, C H; Cleare, A J; Arnone, D

    2016-05-24

    Finding robust brain substrates of mood disorders is an important target for research. The degree to which major depression (MDD) and bipolar disorder (BD) are associated with common and/or distinct patterns of volumetric changes is nevertheless unclear. Furthermore, the extant literature is heterogeneous with respect to the nature of these changes. We report a meta-analysis of voxel-based morphometry (VBM) studies in MDD and BD. We identified studies published up to January 2015 that compared grey matter in MDD (50 data sets including 4101 individuals) and BD (36 data sets including 2407 individuals) using whole-brain VBM. We used statistical maps from the studies included where available and reported peak coordinates otherwise. Group comparisons and conjunction analyses identified regions in which the disorders showed common and distinct patterns of volumetric alteration. Both disorders were associated with lower grey-matter volume relative to healthy individuals in a number of areas. Conjunction analysis showed smaller volumes in both disorders in clusters in the dorsomedial and ventromedial prefrontal cortex, including the anterior cingulate cortex and bilateral insula. Group comparisons indicated that findings of smaller grey-matter volumes relative to controls in the right dorsolateral prefrontal cortex and left hippocampus, along with cerebellar, temporal and parietal regions were more substantial in major depression. These results suggest that MDD and BD are characterised by both common and distinct patterns of grey-matter volume changes. This combination of differences and similarities has the potential to inform the development of diagnostic biomarkers for these conditions.Molecular Psychiatry advance online publication, 24 May 2016; doi:10.1038/mp.2016.72.

  9. An Exceptional Memory

    ERIC Educational Resources Information Center

    Hunter, Ian M. L.

    1977-01-01

    An account is given of the exceptional memory of the late Professor A. C. Aitken who was also a distinguished mathematician and mental calculator. Compared with Shereshevskii, another man with exceptional memory, he shows the scholar's reliance on conceptual mapping rather than the mnemonist's reliance on perceptual chaining. (Editor)

  10. Evidence for Directional Selection at a Novel Major Histocompatibility Class I Marker in Wild Common Frogs (Rana temporaria) Exposed to a Viral Pathogen (Ranavirus)

    PubMed Central

    Teacher, Amber G. F.; Garner, Trenton W. J.; Nichols, Richard A.

    2009-01-01

    Whilst the Major Histocompatibility Complex (MHC) is well characterized in the anuran Xenopus, this region has not previously been studied in another popular model species, the common frog (Rana temporaria). Nor, to date, have there been any studies of MHC in wild amphibian host-pathogen systems. We characterise an MHC class I locus in the common frog, and present primers to amplify both the whole region, and specifically the antigen binding region. As no more than two expressed haplotypes were found in over 400 clones from 66 individuals, it is likely that there is a single class I locus in this species. This finding is consistent with the single class I locus in Xenopus, but contrasts with the multiple loci identified in axolotls, providing evidence that the diversification of MHC class I into multiple loci likely occurred after the Caudata/Anura divergence (approximately 350 million years ago) but before the Ranidae/Pipidae divergence (approximately 230 mya). We use this locus to compare wild populations of common frogs that have been infected with a viral pathogen (Ranavirus) with those that have no history of infection. We demonstrate that certain MHC supertypes are associated with infection status (even after accounting for shared ancestry), and that the diseased populations have more similar supertype frequencies (lower FST) than the uninfected. These patterns were not seen in a suite of putatively neutral microsatellite loci. We interpret this pattern at the MHC locus to indicate that the disease has imposed selection for particular haplotypes, and hence that common frogs may be adapting to the presence of Ranavirus, which currently kills tens of thousands of amphibians in the UK each year. PMID:19240796

  11. fw 2.2:a major QTL controlling fruit weight is common to both red- and green-fruited tomato species.

    PubMed

    Alpert, K B; Grandillo, S; Tanksley, S D

    1995-11-01

    We have shown that a major QTL for fruit weight (fw2.2) maps to the same position on chromosome 2 in the green-fruited wild tomato species, Lycopersicon pennellii and in the red-fruited wild tomato species, L. pimpinellifolium. An introgression line F2 derived from L. esculentum (tomato) x L. pennellii and a backcross 1 (BC1) population derived from L. esculentum x L. pimpinellifolium both place fw2.2 near TG91 and TG167 on chromosome 2 of the tomato highdensity linkage map. fw2.2 accounts for 30% and 47% of the total phenotypic variance in the L. pimpinellifolium and L. pennellii populations, respectively, indicating that this is a major QTL controlling fruit weight in both species. Partial dominance (d/a of 0.44) was observed for the L. pennellii allele of fw 2.2 as compared with the L. esculentum allele. A QTL with very similar phenotypic affects and gene action has also been identified and mapped to the same chromosomal region in other wild tomato accessions: L. cheesmanii and L. pimpinellifolium. Together, these data suggest that fw2.2 represents an orthologous QTL (i.e., derived by speciation as opposed to duplication) common to most, if not all, wild tomato species. High-resolution mapping may ultimately lead to the cloning of this key locus controlling fruit development in tomato.

  12. Three major haplotypes of the β2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder

    PubMed Central

    Diatchenko, Luda; Anderson, Amy D.; Slade, Gary D.; Fillingim, Roger B.; Shabalina, Svetlana A.; Higgins, Tomas; Sama, Swetha; Belfer, Inna; Goldman, David; Max, Mitchell B.; Weir, Bruce S.; Maixner, William

    2008-01-01

    Adrenergic receptor β2 (ADRB2) is a primary target for epinephrine. It plays a critical role in mediating physiological and psychological responses to environmental stressors. Thus, functional genetic variants of ADRB2 will be associated with a complex array of psychological and physiological phenotypes. These genetic variants should also interact with environmental factors such as physical or emotional stress to produce a phenotype vulnerable to pathological states. In this study, we determined whether common genetic variants of ADRB2 contribute to the development of a common chronic pain condition that is associated with increased levels of psychological distress and low blood pressure, factors which are strongly influenced by the adrenergic system. We genotyped 202 female subjects and examined the relationships between three major ADRB2 haplotypes and psychological factors, resting blood pressure, and the risk of developing a chronic musculoskeletal pain condition - Temporomandibular Joint Disorder (TMD). We propose that the first haplotype codes for lower levels of ADRB2 expression, the second haplotype codes for higher ADRB2 expression, and the third haplotype codes for higher receptor expression and rapid agonist-induced internalization. Individuals who carried one haplotype coding for high and one coding for low ADRB2 expression displayed the highest positive psychological traits, had higher levels of resting arterial pressure, and were about 10 times less likely to develop TMD. Thus, our data suggest that either positive or negative imbalances in ADRB2 function increase the vulnerability to chronic pain conditions such as TMD through different etiological pathways that imply the need for tailored treatment options. PMID:16741943

  13. Nothing Exceptional: Against Agamben

    ERIC Educational Resources Information Center

    Colatrella, Steven

    2011-01-01

    Giorgio Agamben's work has become widely influential as a guide to explaining the extra-constitutional powers assumed by governments under the rubric of the War on Terror. His formulations, such as Homo Sacer and State of Exception, have been extended to apply to a wide variety of experiences of repression of liberties or social control, including…

  14. Exceptional Parent, 1996.

    ERIC Educational Resources Information Center

    Klein, Stanley, Ed.

    1996-01-01

    Twelve 1996 issues of "Exceptional Parent" magazine provide a variety of articles and resources on parenting the child or young adult with a disability. The January issue is a resource guide, with directories of national organizations, associations, products, and services. The February issue focuses on early childhood, including articles…

  15. Exceptional Parent, 1995.

    ERIC Educational Resources Information Center

    Klein, Stanley, Ed.

    1995-01-01

    Twelve issues of "Exceptional Parent" magazine provide a variety of articles and resources on parenting the child or young adult with a disability. The January issue is a resource guide with directories of national organizations, associations, products, and services. The February issue focuses on early childhood, including assessment, day care,…

  16. Exceptional Children Research Review.

    ERIC Educational Resources Information Center

    Johnson, G. Orville, Ed.; Blank, Harriett D., Ed.

    Research reviews are presented for eight areas of exceptionality and for administration. Included are the following reports: 16 on the gifted compiled by Edward C. Frierson; 46 on the mentally retarded reviewed by Howard H. Spicker and Nettie R. Bartel; 20 on the visually impaired presented by William J. Tisdall; 44 on the hearing impaired…

  17. Exceptional Parent, 2001.

    ERIC Educational Resources Information Center

    Rader, Rick, Ed.

    2001-01-01

    This document collects the 12 monthly issues of Volume 31 of "Exceptional Parent," a magazine focused on practical advice for parents of children with disabilities. Most of the issues include a focus topic as well as articles on other issues, columns, reviews, and letters. These 12 issues concentrate on the following areas: (1)…

  18. Exceptional Parent, 2000.

    ERIC Educational Resources Information Center

    Rader, Rick, Ed.

    2000-01-01

    This document collects the 12 monthly issues of Volume 30 of "Exceptional Parent," a magazine focused on practical advice for parents of children with disabilities. Most issues include a focus topic as well as articles on other issues, columns, reviews, and letters. The issues focus on the following areas: (1) an extensive resource guide; (2)…

  19. From genome-wide to candidate gene: an investigation of variation at the major histocompatibility complex in common bottlenose dolphins exposed to harmful algal blooms.

    PubMed

    Cammen, Kristina M; Wilcox, Lynsey A; Rosel, Patricia E; Wells, Randall S; Read, Andrew J

    2015-02-01

    The role the major histocompatibility complex (MHC) plays in response to exposure to environmental toxins is relatively poorly understood, particularly in comparison to its well-described role in pathogen immunity. We investigated associations between MHC diversity and resistance to brevetoxins in common bottlenose dolphins (Tursiops truncatus). A previous genome-wide association study investigating an apparent difference in harmful algal bloom (HAB) resistance among dolphin populations in the Gulf of Mexico identified genetic variation associated with survival in close genomic proximity to multiple MHC class II loci. Here, we characterized genetic variation at DQA, DQB, DRA, and DRB loci in dolphins from central-west Florida and the Florida Panhandle, including dolphins that died during HABs and dolphins presumed to have survived HAB exposure. We found that DRB and DQB exhibited patterns of genetic differentiation among geographic regions that differed from neutral microsatellite loci. In addition, genetic differentiation at DRB across multiple pairwise comparisons of live and dead dolphins was greater than differentiation observed at neutral loci. Our findings at these MHC loci did not approach the strength of association with survival previously described for a nearby genetic variant. However, the results provide evidence that selective pressures at the MHC vary among dolphin populations that differ in the frequency of HAB exposure and that the overall composition of DRB variants differs between dolphin survivors and non-survivors of HABs. These results may suggest a potential role of MHC diversity in variable survival of bottlenose dolphins exposed to HABs.

  20. Dibaryons from Exceptional Collections

    NASA Astrophysics Data System (ADS)

    Herzog, Christopher P.; Walcher, Johannes

    2003-09-01

    We discuss aspects of the dictionary between brane configurations in del Pezzo geometries and dibaryons in the dual superconformal quiver gauge theories. The basis of fractional branes defining the quiver theory at the singularity has a K-theoretic dual exceptional collection of bundles which can be used to read off the spectrum of dibaryons in the weakly curved dual geometry. Our prescription identifies the R-charge R and all baryonic U(1) charges QI with divisors in the del Pezzo surface without any Weyl group ambiguity. As one application of the correspondence, we identify the cubic anomaly trRQIQJ as an intersection product for dibaryon charges in large-N superconformal gauge theories. Examples can be given for all del Pezzo surfaces using three- and four-block exceptional collections. Markov-type equations enforce consistency among anomaly equations for three-block collections.

  1. Comparative genome analysis of the major histocompatibility complex (MHC) class I B/C segments in primates elucidated by genomic sequencing in common marmoset (Callithrix jacchus).

    PubMed

    Shiina, Takashi; Kono, Azumi; Westphal, Nico; Suzuki, Shingo; Hosomichi, Kazuyoshi; Kita, Yuki F; Roos, Christian; Inoko, Hidetoshi; Walter, Lutz

    2011-08-01

    Common marmoset monkeys (Callithrix jacchus) have emerged as important animal models for biomedical research, necessitating a more extensive characterization of their major histocompatibility complex (MHC) region. However, the genomic information of the marmoset MHC (Caja) is still lacking. The MHC-B/C segment represents the most diverse MHC region among primates. Therefore, in this paper, to elucidate the detailed gene organization and evolutionary processes of the Caja class I B (Caja-B) segment, we determined two parts of the Caja-B sequences with 1,079 kb in total, ranging from H6orf15 to BAT1 and compared the structure and phylogeny with that of other primates. This segment contains 54 genes in total, nine Caja-B genes (Caja-B1 to Caja-B9), two MIC genes (MIC1 and MIC2), eight non-MHC genes, two non-coding genes, and 33 non-MHC pseudogenes that have not been observed in other primate MHC-B/C segments. Caja-B3, Caja-B4, and Caja-B7 encode proper MHC class I proteins according to amino acid structural characteristics. Phylogenetic relationships based on 48 MHC-I nucleotide sequences in primates suggested (1) species-specific divergence for Caja, Mamu, and HLA/Patr/Gogo lineages, (2) independent generation of the "seven coding exon" type MHC-B genes in Mamu and HLA/Patr/Gogo lineages from an ancestral "eight coding exon" type MHC-I gene, (3) parallel correlation with the long and short segmental duplication unit length in Caja and Mamu lineages. These findings indicate that the MHC-B/C segment has been under permanent selective pressure in the evolution of primates.

  2. Are There Common Familial Influences for Major Depressive Disorder and an Overeating-Binge Eating Dimension in both European-American and African-American Female Twins?

    PubMed Central

    Munn-Chernoff, Melissa A.; Grant, Julia D.; Agrawal, Arpana; Koren, Rachel; Glowinski, Anne L.; Bucholz, Kathleen K.; Madden, Pamela A. F.; Heath, Andrew C.; Duncan, Alexis E.

    2014-01-01

    Objective Although prior studies have demonstrated that depression is associated with an overeating-binge eating dimension (OE-BE), phenotypically, little research has investigated whether familial factors contribute to the co-occurrence of these phenotypes, especially in community samples with multiple racial/ethnic groups. We examined the extent to which familial (i.e., genetic and shared environmental) influences overlapped between Major Depressive Disorder (MDD) and OE-BE in a population-based sample and whether these influences were similar across racial/ethnic groups Method Participants included 3226 European-American (EA) and 550 African-American (AA) young adult women from the Missouri Adolescent Female Twin Study. An adaptation of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA) was administered to assess lifetime DSM-IV MDD and OE-BE. Quantitative genetic modeling was used to estimate familial influences between both phenotypes; all models controlled for age. Results The best-fitting model, which combined racial/ethnic groups, found that additive genetic influences accounted for 44% (95% CI: 34%, 53%) of the MDD variance and 40% (25%, 54%) for OE-BE, with the remaining variances due to non-shared environmental influences. Genetic overlap was substantial (rg = .61 [.39, .85]); non-shared environmental influences on MDD and OE-BE overlapped weakly (re = .26 [.09, .42]) Discussion Results suggest that common familial influences underlie MDD and OE-BE, and the magnitude of familial influences contributing to the comorbidity between MDD and OE-BE is similar between EA and AA women. If racial/ethnic differences truly exist, then larger sample sizes may be needed to fully elucidate familial risk for comorbid MDD and OE-BE across these groups. PMID:24659561

  3. Counseling Exceptional People.

    ERIC Educational Resources Information Center

    Benjamin, Libby; Walz, Garry R.

    This guide offers counselors and special education and classroom teachers assistance in counseling handicapped children. Major articles focus on counseling children who are mentally retarded, emotionally, visually and hearing impaired, learning disabled, and gifted. Additional information is provided on: (1) sexual fulfillment for the handicapped;…

  4. The major nucleoside triphosphatase in pea (Pisum sativum L.) nuclei and in rat liver nuclei share common epitopes also present in nuclear lamins

    NASA Technical Reports Server (NTRS)

    Tong, C. G.; Dauwalder, M.; Clawson, G. A.; Hatem, C. L.; Roux, S. J.

    1993-01-01

    The major nucleoside triphosphatase (NTPase) activities in mammalian and pea (Pisum sativum L.) nuclei are associated with enzymes that are very similar both biochemically and immunochemically. The major NTPase from rat liver nuclei appears to be a 46-kD enzyme that represents the N-terminal portion of lamins A and C, two lamina proteins that apparently arise from the same gene by alternate splicing. Monoclonal antibody (MAb) G2, raised to human lamin C, both immunoprecipitates the major (47 kD) NTPase in pea nuclei and recognizes it in western blot analyses. A polyclonal antibody preparation raised to the 47-kD pea NTPase (pc480) reacts with the same lamin bands that are recognized by MAb G2 in mammalian nuclei. The pc480 antibodies also bind to the same lamin-like bands in pea nuclear envelope-matrix preparations that are recognized by G2 and three other MAbs known to bind to mammalian lamins. In immunofluorescence assays, pc480 and anti-lamin antibodies stain both cytoplasmic and nuclear antigens in plant cells, with slightly enhanced staining along the periphery of the nuclei. These results indicate that the pea and rat liver NTPases are structurally similar and that, in pea nuclei as in rat liver nuclei, the major NTPase is probably derived from a lamin precursor by proteolysis.

  5. Students' Strategies for Exception Handling

    ERIC Educational Resources Information Center

    Rashkovits, Rami; Lavy, Ilana

    2011-01-01

    This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

  6. Discovery of A New Retrograde Trans-Neptunian Object: Hint of A Common Orbital Plane for Low Semi-Major Axis, High Inclination TNOs and Centaurs

    NASA Astrophysics Data System (ADS)

    Chen, Ying-Tung; Lin, Hsing-Wen; Holman, Matthew J.; Payne, Matthew John; Fraser, Wesley Cristopher; Lacerda, Pedro; Ip, Wing-Huen; Pan-STARRS 1 Builders

    2016-10-01

    The origin of high inclination objects beyond Jupiter, including trans-Neptunian objects (TNOs) and Centaurs, remains uncertain. We report the discovery of a retrograde TNO, which we nickname "Niku", detected by the Pan-STARRS 1 Outer Solar System Survey. The numerical integrations show that the orbital dynamics of Niku are very similar to those of 2008 KV42 (Drac), with a half-life of ~ 500 Myr and analogous orbital evolution. Comparing similar high inclination members announced by the Minor-Planet Center (q > 10 AU, a < 100 AU and i > 60), we find these objects exhibit a surprising clustering of ascending node, populating a common orbital plane. The statistical significance of 3.8-sigma suggests it is unlikely to be coincidental. An unknown mechanism is required to explain the observed clustering. This discovery may provide a pathway to investigating a possible reservoir of high-inclination objects.

  7. An USH2A founder mutation is the major cause of Usher syndrome type 2 in Canadians of French origin and confirms common roots of Quebecois and Acadians

    PubMed Central

    Ebermann, Inga; Koenekoop, Robert K; Lopez, Irma; Bou-Khzam, Lara; Pigeon, Renée; Bolz, Hanno J

    2009-01-01

    Congenital hearing loss affects approximately one child in 1000. About 10% of the deaf population have Usher syndrome (USH). In USH, hearing loss is complicated by retinal degeneration with onset in the first (USH1) or second (USH2) decade. In most populations, diagnostic testing is hampered by a multitude of mutations in nine genes. We have recently shown that in French Canadians from Quebec, USH1 largely results from a single USH1C founder mutation, c.216G>A (‘Acadian allele'). The genetic basis of USH2 in Canadians of French descent, however, has remained elusive. Here, we have investigated nine USH2 families from Quebec and New Brunswick (the former Acadia) by haplotype analyses of the USH2A locus and sequencing of the three known USH2 genes. Seven USH2A mutations were identified in eight patients. One of them, c.4338_4339delCT, accounts for 10 out of 18 disease alleles (55.6%). This mutation has previously been reported in an Acadian USH2 family, and it was found in homozygous state in the three Acadians of our sample. As in the case of c.216G>A (USH1C), a common haplotype is associated with c.4338_4339delCT. With a limited number of molecular tests, it will now be possible in these populations to estimate whether children with congenital hearing impairment of different degrees will develop retinal disease – with important clinical and therapeutic implications. USH2 is the second example that reveals a significant genetic overlap between Quebecois and Acadians: in contrast to current understanding, other genetic disorders present in both populations are likely based on common founder mutations as well. PMID:18665195

  8. Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins

    PubMed Central

    Marsolais, Frédéric

    2012-01-01

    The lack of phaseolin and phytohaemagglutinin in common bean (dry bean, Phaseolus vulgaris) is associated with an increase in total cysteine and methionine concentrations by 70% and 10%, respectively, mainly at the expense of an abundant non-protein amino acid, S-methyl-cysteine. Transcripts were profiled between two genetically related lines differing for this trait at four stages of seed development using a high density microarray designed for common bean. Transcripts of multiple sulphur-rich proteins were elevated, several previously identified by proteomics, including legumin, basic 7S globulin, albumin-2, defensin, albumin-1, the Bowman–Birk type proteinase inhibitor, the double-headed trypsin inhibitor, and the Kunitz trypsin inhibitor. A co-ordinated regulation of transcripts coding for sulphate transporters, sulphate assimilatory enzymes, serine acetyltransferases, cystathionine β-lyase, homocysteine S-methyltransferase and methionine gamma-lyase was associated with changes in cysteine and methionine concentrations. Differential gene expression of sulphur-rich proteins preceded that of sulphur metabolic enzymes, suggesting a regulation by demand from the protein sink. Up-regulation of SERAT1;1 and -1;2 expression revealed an activation of cytosolic O-acetylserine biosynthesis. Down-regulation of SERAT2;1 suggested that cysteine and S-methyl-cysteine biosynthesis may be spatially separated in different subcellular compartments. Analysis of free amino acid profiles indicated that enhanced cysteine biosynthesis was correlated with a depletion of O-acetylserine. These results contribute to our understanding of the regulation of sulphur metabolism in developing seed in response to a change in the composition of endogenous proteins. PMID:23066144

  9. Transcripts of sulphur metabolic genes are co-ordinately regulated in developing seeds of common bean lacking phaseolin and major lectins.

    PubMed

    Liao, Dengqun; Pajak, Agnieszka; Karcz, Steven R; Chapman, B Patrick; Sharpe, Andrew G; Austin, Ryan S; Datla, Raju; Dhaubhadel, Sangeeta; Marsolais, Frédéric

    2012-10-01

    The lack of phaseolin and phytohaemagglutinin in common bean (dry bean, Phaseolus vulgaris) is associated with an increase in total cysteine and methionine concentrations by 70% and 10%, respectively, mainly at the expense of an abundant non-protein amino acid, S-methyl-cysteine. Transcripts were profiled between two genetically related lines differing for this trait at four stages of seed development using a high density microarray designed for common bean. Transcripts of multiple sulphur-rich proteins were elevated, several previously identified by proteomics, including legumin, basic 7S globulin, albumin-2, defensin, albumin-1, the Bowman-Birk type proteinase inhibitor, the double-headed trypsin inhibitor, and the Kunitz trypsin inhibitor. A co-ordinated regulation of transcripts coding for sulphate transporters, sulphate assimilatory enzymes, serine acetyltransferases, cystathionine β-lyase, homocysteine S-methyltransferase and methionine gamma-lyase was associated with changes in cysteine and methionine concentrations. Differential gene expression of sulphur-rich proteins preceded that of sulphur metabolic enzymes, suggesting a regulation by demand from the protein sink. Up-regulation of SERAT1;1 and -1;2 expression revealed an activation of cytosolic O-acetylserine biosynthesis. Down-regulation of SERAT2;1 suggested that cysteine and S-methyl-cysteine biosynthesis may be spatially separated in different subcellular compartments. Analysis of free amino acid profiles indicated that enhanced cysteine biosynthesis was correlated with a depletion of O-acetylserine. These results contribute to our understanding of the regulation of sulphur metabolism in developing seed in response to a change in the composition of endogenous proteins.

  10. Mapping of major diseases and devising prevention and control regimen to common diseases in cattle and shoats in Dassenech district of South Omo Zone, South-Western Ethiopia.

    PubMed

    Molla, Bereket; Delil, Faris

    2015-01-01

    Livestock production system, particularly in pastoral areas, is mainly constrained by rampant livestock diseases and seasonal feed and water shortages. In areas like Dassenech, bordering Kenya and South Sudan, this risks are pronounced due to the unavailability of appropriate prevention and control. The research was conducted with the objectives of identifying major rampant diseases and designing appropriate prevention and control strategies. A cross-sectional study was employed, conducted using both participatory epidemiology and conventional veterinary investigation. Spatial and temporal occurrence of diseases was assessed. The major five diseases in bovine were contagious bovine pleuro pneumonia (CBPP), septicemic pasteurellosis, anthrax, foot and mouth disease (FMD), and black leg, in that order of importance. Similarly, in ovine, "unknown recent disease," pneumonic pasteurellosis, brucellosis, peste des petits ruminants (PPR), and septicemic pasteurellosis were ranked, starting from the most important whereas in caprine PPR, contagious caprine pleuro pneumonia (CCPP), goat pox, brucellosis, and pneumonic pasteurellosis were ranked in that order of importance. The seroprevalence in bovine were found to be 97, 10, 18, and 15% for septicemic pasteurelosis, CBPP, FMD, and brucellosis, respectively. The seroprevalence of septicemic pasteurelosis, PPR, and brucellosis was 86, 49, and 3%, respectively, in ovine. The seroprevalence of caprine sera for CCPP, PPR, and brucellosis were 87, 42, and 0%, respectively. The prevention and control regimen, vaccination against CBPP, should be at the beginning of wet season, whereas, for FMD, it should be at the end of wet season in bovine. Brucellosis for bovine, if has to be applied, should be at the beginning of dry season. PPR vaccination for ovine should be at the beginning of wet season whereas, for caprine, it should be just before start of dry season. Furthermore, the efficacy of aforementioned vaccines and its protocol

  11. Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb-Drug Interactions

    PubMed Central

    Awortwe, Charles; Bouic, Patrick J.; Masimirembwa, Collen M.; Rosenkranz, Bernd

    2015-01-01

    The purpose of this study was to evaluate the potential risk of common herbal medicines used by HIV-infected patients in Africa for herb-drug interactions (HDI). High throughput screening assays consisting of recombinant Cytochrome P450 enzymes (CYPs) and fluorescent probes, and parallel artificial membrane permeability assays (PAMPA) were used. The potential of herbal medicines to cause HDI was ranked according to FDA guidelines for reversible inhibition and categorization of time dependent inhibition was based on the normalized ratio. CYPs 1A2 and 3A4 were most inhibited by the herbal extracts. H. hemerocallidea (IC50 = 0.63 μg/mL and 58 μg/mL) and E. purpurea (IC50 = 20 μg/mL and 12 μg/mL) were the potent inhibitors of CYPs 1A2 and 3A4 respectively. L. frutescens and H. hemerocallidea showed clear time dependent inhibition on CYP3A4. Furthermore, the inhibitory effect of both H. hemerocallidea and L. frutescens before and after PAMPA were identical. The results indicate potential HDI of H. hemerocallidea, L. frutescens and E. purpurea with substrates of the affected enzymes if maximum in vivo concentration is achieved. PMID:24475926

  12. The X-Factor: an evaluation of common methods used to analyse major inter-segment kinematics during the golf swing.

    PubMed

    Brown, Susan J; Selbie, W Scott; Wallace, Eric S

    2013-01-01

    A common biomechanical feature of a golf swing, described in various ways in the literature, is the interaction between the thorax and pelvis, often termed the X-Factor. There is no consistent method used within golf biomechanics literature however to calculate these segment interactions. The purpose of this study was to examine X-factor data calculated using three reported methods in order to determine the similarity or otherwise of the data calculated using each method. A twelve-camera three-dimensional motion capture system was used to capture the driver swings of 19 participants and a subject specific three-dimensional biomechanical model was created with the position and orientation of each model estimated using a global optimisation algorithm. Comparison of the X-Factor methods showed significant differences for events during the swing (P < 0.05). Data for each kinematic measure were derived as a times series for all three methods and regression analysis of these data showed that whilst one method could be successfully mapped to another, the mappings between methods are subject dependent (P <0.05). Findings suggest that a consistent methodology considering the X-Factor from a joint angle approach is most insightful in describing a golf swing.

  13. Tryptophan kynurenine metabolism as a common mediator of genetic and environmental impacts in major depressive disorder: the serotonin hypothesis revisited 40 years later.

    PubMed

    Oxenkrug, Gregory F

    2010-01-01

    The original 1969 Lancet paper proposed in depression the activity of liver tryptophan-pyrrolase is stimulated by raised blood corticosteroids levels, and metabolism of tryptophan is shunted away from serotonin production, and towards kynurenine production. Discovery of neurotropic activity of kynurenines suggested that up-regulation of the tryptophan-kynurenine pathway not only augmented serotonin deficiency but also underlined depression-associated anxiety, psychosis and cognitive decline. The present review of genetic and hormonal factors regulating kynurenine pathway of tryptophan metabolism suggests that this pathway mediates both genetic and environmental mechanisms of depression. Rate-limiting enzymes of kynurenine formation, tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are activated by stress hormones (TDO) and/or by pro-inflammatory cytokines (IDO). Simultaneous presence of high producers alleles of proinflammatory cytokines genes (e.g., interferon-gamma and tumor necrosis factor-alpha) determines the genetic predisposition to depression via up-regulation of IDO while impact of environmental stresses is mediated via hormonal activation of TDO. Tryptophan-kynurenine pathway represents a major meeting point of gene-environment interaction in depression and a new target for pharmacological intervention.

  14. Major Contribution of Flowering Time and Vegetative Growth to Plant Production in Common Bean As Deduced from a Comparative Genetic Mapping.

    PubMed

    González, Ana M; Yuste-Lisbona, Fernando J; Saburido, Soledad; Bretones, Sandra; De Ron, Antonio M; Lozano, Rafael; Santalla, Marta

    2016-01-01

    Determinacy growth habit and accelerated flowering traits were selected during or after domestication in common bean. Both processes affect several presumed adaptive traits such as the rate of plant production. There is a close association between flowering initiation and vegetative growth; however, interactions among these two crucial developmental processes and their genetic bases remain unexplored. In this study, with the aim to establish the genetic relationships between these complex processes, a multi-environment quantitative trait locus (QTL) mapping approach was performed in two recombinant inbred line populations derived from inter-gene pool crosses between determinate and indeterminate genotypes. Additive and epistatic QTLs were found to regulate flowering time, vegetative growth, and rate of plant production. Moreover, the pleiotropic patterns of the identified QTLs evidenced that regions controlling time to flowering traits, directly or indirectly, are also involved in the regulation of plant production traits. Further QTL analysis highlighted one QTL, on the lower arm of the linkage group Pv01, harboring the Phvul.001G189200 gene, homologous to the Arabidopsis thaliana TERMINAL FLOWER1 (TFL1) gene, which explained up to 32% of phenotypic variation for time to flowering, 66% for vegetative growth, and 19% for rate of plant production. This finding was consistent with previous results, which have also suggested Phvul.001G189200 (PvTFL1y) as a candidate gene for determinacy locus. The information here reported can also be applied in breeding programs seeking to optimize key agronomic traits, such as time to flowering, plant height and an improved reproductive biomass, pods, and seed size, as well as yield.

  15. Major Contribution of Flowering Time and Vegetative Growth to Plant Production in Common Bean As Deduced from a Comparative Genetic Mapping

    PubMed Central

    González, Ana M.; Yuste-Lisbona, Fernando J.; Saburido, Soledad; Bretones, Sandra; De Ron, Antonio M.; Lozano, Rafael; Santalla, Marta

    2016-01-01

    Determinacy growth habit and accelerated flowering traits were selected during or after domestication in common bean. Both processes affect several presumed adaptive traits such as the rate of plant production. There is a close association between flowering initiation and vegetative growth; however, interactions among these two crucial developmental processes and their genetic bases remain unexplored. In this study, with the aim to establish the genetic relationships between these complex processes, a multi-environment quantitative trait locus (QTL) mapping approach was performed in two recombinant inbred line populations derived from inter-gene pool crosses between determinate and indeterminate genotypes. Additive and epistatic QTLs were found to regulate flowering time, vegetative growth, and rate of plant production. Moreover, the pleiotropic patterns of the identified QTLs evidenced that regions controlling time to flowering traits, directly or indirectly, are also involved in the regulation of plant production traits. Further QTL analysis highlighted one QTL, on the lower arm of the linkage group Pv01, harboring the Phvul.001G189200 gene, homologous to the Arabidopsis thaliana TERMINAL FLOWER1 (TFL1) gene, which explained up to 32% of phenotypic variation for time to flowering, 66% for vegetative growth, and 19% for rate of plant production. This finding was consistent with previous results, which have also suggested Phvul.001G189200 (PvTFL1y) as a candidate gene for determinacy locus. The information here reported can also be applied in breeding programs seeking to optimize key agronomic traits, such as time to flowering, plant height and an improved reproductive biomass, pods, and seed size, as well as yield. PMID:28082996

  16. From Ethical Exceptionalism to Ethical Exceptions: The Rule and exception Model and the Changing Meaning of Ethics In German Bioregulation.

    PubMed

    Braun, Kathrin

    2016-02-12

    Germany is an interesting case with respect to the governance of reprogenetics. It has a strong profile in the technosciences and high aims regarding the global bioeconomy, yet her regulation of human genetics, reproductive medicine and embryo research has for a long time been rather restrictive. German biopolitical exceptionalism has often been explained by reference to Catholicism and the legacy of the Nazi past. The Germans, so goes the common story, have learnt the lessons of history and translated them into unconditional respect for human dignity, which in turn translates into unconditional protection of human life, including the human embryo, and the firm repudiation of any eugenic distinction between 'life worth to live' and 'life not worth to live'. This, however, is not the whole story. Alongside deontological strictness we find another strand of governing body politics and reprogenetics in Germany, the rule-and-exception model, running from the mid-1970s abortion law via the 2002 Stem Cell Act to the 2011 regulation of pre-implantation genetic diagnosis. In contrast to the former, that strongly draws on Kant and his concept of human dignity, the latter bears resemblances to Carl Schmitt's concept of state of exception. The article will show that the rule-and-exception model builds the exception into the rule and transforms the meaning and mandate of ethics, namely from safeguarding ethical standards to deciding about the exception. Given that the exception has now tended to become the rule, the question is whether the lessons of history will govern German reprogenetics for much longer.

  17. Hsp70 and small Hsps are the major heat shock protein members involved in midgut metamorphosis in the common cutworm, Spodoptera litura.

    PubMed

    Gu, J; Huang, L-X; Shen, Y; Huang, L-H; Feng, Q-L

    2012-10-01

    Heat shock proteins (Hsps) are important chaperones, which are involved in various signal pathways and regulate lots of physiological processes. Early research suggested that some Hsps are involved in insect development. However, few studies have been carried out to explore the roles of Hsps, especially in larval-pupal metamorphosis. In the present study, 49 Hsp unigenes were identified in the Spodoptera litura transcriptome and their mRNA expression profiles during midgut metamorphosis were examined using a tag-based digital gene expression system. The genes with the most different levels of expression were then cloned and their expression patterns in midguts from sixth instar larvae to pupae were analysed using real time quantitative PCR. The responses of these genes to juvenile hormone (JH) and 20-hydroxyecdysone (20E) were also studied. The results showed that the mRNA levels of 22 Hsp unigenes changed significantly during midgut metamorphosis. Amongst these 22 unigenes, hsp70, hsp20.4 and hsp20.8 were the most up-regulated members, and hsp15.9, hsp19.3 and hsp22.0 were the most down-regulated ones. Further studies showed that hsp70, hsp20.4 and hsp20.8 were remarkably up-regulated by JH. In addition, 20E slightly increased the mRNA levels of both hsp20.4 and hsp20.8. However, hsp15.9, hsp19.3 and hsp22.0 did not respond to either JH or 20E. These results indicate that Hsp70 and small Hsps (sHsps) are probably the major players in midgut metamorphosis in S. litura. The current findings provide valuable insights into the roles of the Hsp superfamily in insect metamorphosis.

  18. Hypotonicity-activated efflux of taurine and myo-inositol in rat inner medullary collecting duct cells: evidence for a major common pathway.

    PubMed

    Ruhfus, B; Kinne, R K

    1996-01-01

    To further characterize the hypotonicity-activated efflux pathways for the organic osmolytes taurine and myo-inositol in inner medullary collecting duct (IMCD) cells tracer fluxes of taurine and myo-inositol were investigated. The time course of activation of both fluxes after exposure of cells isolated at 600 mosm to a hypotonic medium (300 mosm by omission of sucrose) was identical with a major increase of release within the first 10 min. All 'anion channel blockers' employed proved to be strong inhibitors of both fluxes. Inhibition of myo-inositol efflux by 0.5 mM NPPB and 0.1 mM dideoxyforskolin was not significantly different from that of taurine efflux (87.7 +/- 11.4 compared to 94.6 +/- 4.6% and 98.8 +/- 2.0 compared to 95.9 +/- 3.7%). However, SITS (0.5 and 0.01 mM), DIDS (0.5 and 0.01 mM), and niflumic acid (0.5 mM) inhibited myo-inositol efflux more strongly than taurine efflux. The respective values were 65.4 +/- 4 vs. 42.9 +/- 3.6% for 0.01 mM SITS, 65.7 +/- 4.2 vs. 45.8 +/- 2.0% for 0.01 mM DIDS, and 79.5 +/- 3.5 vs. 54.2 +/- 2.5% for 0.5 mM niflumic acid. Taurine as well as myo-inositol efflux were decreased to a similar extent by 10 mM extracellular ATP (26.9 +/- 6.3 vs. 29.8 +/- 17.7% inhibition), by 10 mM extracellular cAMP (52.8 +/- 9.8 vs. 60.1 +/- 17.2% inhibition) and by reduction of the intracellular ATP content employing 2-deoxy-D-glucose (31.9 +/- 5.9 vs. 40.4 +/- 13.6% inhibition). In polarized primary cell cultures taurine and myo-inositol were released during a hypotonic shock primarily across the basal-lateral membrane, the ratio of basolateral versus apical efflux was 4.1 for taurine and 3.9 for myo-inositol. Apical fluxes were more sensitive to 0.01 mM SITS or DIDS; this was particularly evident for apical myo-inositol efflux which was inhibited by 0.01 mM SITS by 84.1 +/- 5.9% compared to 43.5 +/- 13.1% inhibition of the basolateral efflux. Thus, taurine and myo-inositol efflux show to a great extent a similar cellular distribution

  19. Major depression.

    PubMed

    Bentley, Susan M; Pagalilauan, Genevieve L; Simpson, Scott A

    2014-09-01

    Major depression is a common, disabling condition seen frequently in primary care practices. Non-psychiatrist ambulatory providers are increasingly responsible for diagnosing, and primarily managing patients suffering from major depressive disorder (MDD). The goal of this review is to help primary care providers to understand the natural history of MDD, identify practical tools for screening, and a thoughtful approach to management. Clinically challenging topics like co-morbid conditions, treatment resistant depression and pharmacotherapy selection with consideration to side effects and medication interactions, are also covered.

  20. BEHAVIORAL RESEARCH ON EXCEPTIONAL CHILDREN.

    ERIC Educational Resources Information Center

    KIRK, SAMUEL A.; WEINER, BLUMA B.

    THIS MONOGRAPH PROVIDES REVIEWS OF BEHAVIORAL RESEARCH STUDIES WHICH INCLUDE AUTHOR, TITLE, PURPOSE, SUBJECTS, METHODS OR PROCEDURES, AND RESULTS. REVIEWS ARE GROUPED BY 11 EXCEPTIONALITY AREAS AND ADMINISTRATION OF SPECIAL EDUCATION. THE AREAS OF EXCEPTIONALITY ARE (1) GIFTED, (2) EDUCABLE MENTALLY RETARDED, (3) TRAINABLE MENTALLY RETARDED, (4)…

  1. A World of Exceptional Children.

    ERIC Educational Resources Information Center

    Conroy, Elizabeth H.; And Others

    This fifth chapter in "Elementary School Counseling in a Changing World" contains four journal articles which focus on exceptional children and helping elementary school counselors build a supportive learning environment for exceptional children. "Primary Prevention for Gifted Students: A Parent Education Group" by Elizabeth Conroy describes a…

  2. Gifted Students with Disabilities: "Twice Exceptionality" in the Music Classroom

    ERIC Educational Resources Information Center

    Abramo, Joseph Michael

    2015-01-01

    Many music educators teach students who are both gifted and possess a learning disability--what is commonly referred to as "twice exceptionality." This article describes some characteristics of twice-exceptional students, the challenges these students often face in school, and some strategies music educators can use to properly…

  3. No Common Opinion on the Common Core

    ERIC Educational Resources Information Center

    Henderson, Michael B.; Peterson, Paul E.; West, Martin R.

    2015-01-01

    According to the three authors of this article, the 2014 "EdNext" poll yields four especially important new findings: (1) Opinion with respect to the Common Core has yet to coalesce. The idea of a common set of standards across the country has wide appeal, and the Common Core itself still commands the support of a majority of the public.…

  4. Collaborative care documentation by exception system.

    PubMed Central

    Ashworth, G. B.; Aubrey, C.

    1992-01-01

    Development of a workstation-based documentation system supporting collaborative care and nurse charting by exception has been underway for the last two and one-half years at Vanderbilt University Medical Center in Nashville, Tennessee. The Pathways system has undergone two major revisions and is currently implemented on three nursing units. The system supports collaborative care by providing a mechanism for entry and printing of collaborative care pathways and collection of exception data. Paper flowsheets for manual charting are generated based on the patient's collaborative pathway and individual needs. The Pathways system has significantly decreased nursing time and effort for documentation. This paper describes the development, implementation, and impact of the workstation-based documentation system. PMID:1482850

  5. Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease.

    PubMed Central

    Blander, S J; Horwitz, M A

    1993-01-01

    We have examined the capacity of the major cytoplasmic membrane protein (MCMP) of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, to induce protective immunity in a guinea pig model of Legionnaires' disease. We purified MCMP to homogeneity from L. pneumophila by buffer extraction, ion-exchange chromatography, and molecular sieve chromatography. Guinea pigs immunized with MCMP developed a strong cell-mediated immune response to the immunogen manifest by marked cutaneous delayed-type hypersensitivity. Guinea pigs immunized with MCMP and then challenged with a lethal aerosol dose of L. pneumophila exhibited a high level of protective immunity. Altogether, in four independent experiments, 55 of 64 (86%) animals immunized three times with 0.6-40 micrograms MCMP including 11 of 11 (100%) animals immunized three times with 40 micrograms MCMP survived aerosol challenge with L. pneumophila compared with 1 of 29 (3%) sham-immunized control animals (P < 0.0001, Cochran-Mantel-Haenszel X2 statistic for pooled data). To our knowledge, MCMP is the first member of the hsp 60 family of proteins shown to induce protective immunity to a microbial pathogen. MCMP has potential as a vaccine against Legionnaires' disease. Since MCMP is a genus common antigen, vaccination with a combination of MCMPs derived from different Legionella species has the potential of inducing protective immunity against all the major Legionella species causing human disease. Images PMID:8432872

  6. 77 FR 41458 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This.... Department of Education Office for Civil Confidential DB120030 03/30/2012 Rights. Assistant. Office of the... Director of Public DM120076 03/13/2012 Management Agency. Affairs. U.S. Customs and Advisor DM120078...

  7. Grading Exceptional and Struggling Learners

    ERIC Educational Resources Information Center

    Jung, Lee Ann; Guskey, Thomas R.

    2011-01-01

    How can you ensure that you are grading your exceptional students fairly? Teachers receive very little guidance for grading students with disabilities, English learners, and those receiving services through a response-to-intervention (RTI) process. This practitioner-friendly book provides teachers and administrators with an effective framework for…

  8. An Investigation of Exceptional Twins.

    ERIC Educational Resources Information Center

    Crismore, Avon

    The author, herself a mother of twins, reviews research on exceptional twins. She considers reasons for fascination with twins and comments upon important advances in technology. Current research in Indianapolis to measure cognitive, perceptual, personality, and chromosome patterns of twins is described. Differences in the makeup of identical and…

  9. 75 FR 52376 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    ... [Federal Register Volume 75, Number 164 (Wednesday, August 25, 2010)] [Notices] [Pages 52376-52377] [FR Doc No: 2010-21069] OFFICE OF PERSONNEL MANAGEMENT Excepted Service AGENCY: U.S. Office of.... 218. John Berry, Director, U.S. Office of Personnel Management. [FR Doc. 2010-21069 Filed 8-24-10;...

  10. 78 FR 28652 - Excepted Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM). ACTION: Notice. SUMMARY: This... the Office of Personnel Management (OPM) publishes a notice of agency-specific authorities established... 3302; E.O. 10577, 3 CFR, 1954-1958 Comp., p. 218. U.S. Office of Personnel Management. Elaine...

  11. Insecticidal activity of an essential oil of Tagetes patula L. (Asteraceae) on common bed bug Cimex lectularius L. and molecular docking of major compounds at the catalytic site of ClAChE1.

    PubMed

    Politi, Flávio Augusto Sanches; Nascimento, Juliana Damieli; da Silva, Alexander Alves; Moro, Isabela Jacob; Garcia, Mariana Lopes; Guido, Rafael Victório Carvalho; Pietro, Rosemeire Cristina Linhari Rodrigues; Godinho, Antônio Francisco; Furlan, Maysa

    2017-01-01

    Emerging resistance to insecticides has influenced pharmaceutical research and the search for alternatives to control the common bed bug Cimex lectularius. In this sense, natural products can play a major role. Tagetes patula, popularly known as dwarf marigold, is a plant native to North America with biocide potential. The aim of this work was to evaluate the biological activity of T. patula essential oil (EO) against adult common bed bugs via exposure to dry residues by the Impregnated Paper Disk Test (IPDT) using cypermethrin as a positive control. We selected the enzyme acetylcholinesterase as a target for modeling studies, with the intent of investigating the molecular basis of any biological activity of the EO. Chemical analysis of the EO was performed using gas chromatography coupled to mass spectrometry (GC-MS). Additionally, oral and dermal acute toxicity tests were performed according to Organization for Economic Cooperation and Development (OECD) guidelines. The sulforhodamine B assay (SRB) was performed to verify the cytotoxicity of EO to HaCaT cells. The EO eliminated 100 % of the bed bugs at 100 mg mL(-1) with an LC50 value of 15.85 mg mL(-1). GC-MS analysis identified α-terpinolene, limonene, piperitenone, and piperitone as major components of the mixture. Molecular modeling studies of these major compounds suggested that they are acetylcholinesterase inhibitors with good steric and electronic complementarity. The in vitro cytotoxicity evaluation revealed a LC50 = 37.06 μg mL(-1) and in vivo acute toxicity showed an LC50 >4000 mg kg(-1), indicating that the EO presents low risk of toxic side effects in humans. The T. patula essential oil components provide a promising strategy for controlling bed bug populations with low mammalian toxicity. These findings pave the way for further in vivo studies aimed at developing a safe and effective insecticide.

  12. Exceptional fossil preservation and the cambrian explosion.

    PubMed

    Butterfield, Nicholas J

    2003-02-01

    Exceptionally preserved, non-biomineralizing fossils contribute importantly to resolving details of the Cambrian explosion, but little to its overall patterns. Six distinct "types" of exceptional preservation are identified for the terminal Proterozoic-Cambrian interval, each of which is dependent on particular taphonomic circumstances, typically restricted both in space and time. Taphonomic pathways yielding exceptional preservation were particularly variable through the Proterozoic-Cambrian transition, at least in part a consequence of contemporaneous evolutionary innovations. Combined with the reasonably continuous record of "Doushantuo-type preservation," and the fundamentally more robust records of shelly fossils, phytoplankton cysts and trace fossils, these taphonomic perturbations contribute to the documentation of major evolutionary and biogeochemical shifts through the terminal Proterozoic and early Cambrian.Appreciation of the relationship between taphonomic pathway and fossil expression serves as a useful tool for interpreting exceptionally preserved, often problematic, early Cambrian fossils. In shale facies, for example, flattened non-biomineralizing structures typically represent the remains of degradation-resistant acellular and extracellular "tissues" such as chaetae and cuticles, whereas three-dimensional preservation represents labile cellular tissues with a propensity for attracting and precipitating early diagenetic minerals. Such distinction helps to identify the acuticular integument of hyolithids, the chaetae-like nature of Wiwaxia sclerites, the chaetognath-like integument of Amiskwia, the midgut glands of various Burgess Shale arthropods, and the misidentification of deposit-feeding arthropods in the Chengjiang biota. By the same reasoning, putative lobopods in the Sirius Passet biota and putative deuterostomes in the Chengiang biota are better interpreted as arthropods.

  13. A comparative study of the role of the major proteinases of germinated common bean (Phaseolus vulgaris L.) and soybean (Glycine max (L.) Merrill) seeds in the degradation of their storage proteins.

    PubMed

    Zakharov, A; Carchilan, M; Stepurina, T; Rotari, V; Wilson, K; Vaintraub, I

    2004-10-01

    Two types of cysteine proteases, low-specificity enzymes from the papain family and Asn-specific from the legumain family are generally considered to be the major endopeptidases responsible for the degradation of seed storage proteins during early seedling growth. The action of the corresponding enzymes (CPPh1 and LLP, respectively) from common bean (Phaseolus vulgaris L.) on phaseolin (the common bean storage protein), and on the homologous soybean (Glycine max (L.) Merrill) storage protein, beta-conglycinin, was studied. Under the action of LLP, proteolysis of phaseolin was limited to cleavage of its interdomain linker. No cleavage of the interdomain linker occurred in beta-conglycinin with LLP. LLP action was restricted to splitting off the disordered N-terminal extensions of alpha and alpha' subunits. No extensive hydrolysis (degradation to short TCA-soluble peptides) of either protein occurred under the action of LLP. CPPh1 cleaved the phaseolin subunits into roughly half-sized fragments at the onset of proteolysis. The cleavage was accompanied by a small (8-10%) decrease of protein. No decrease of protein occurred with further incubation. Thus the two most active proteinases detected in common bean seedlings individually were incapable of the extensive degradation of phaseolin. Extensive hydrolysis of phaseolin was only achieved by the consecutive action of LLP and CPPh1. Similar cleavages occurred during the action of CPPh1 on beta-conglycinin. However, by contrast with phaseolin, CPPh1 by itself accomplished the extensive hydrolysis of beta-conglycinin. The differences in the course of proteolysis of the proteins studied were determined by their structural peculiarities.

  14. Common Cold

    MedlinePlus

    ... nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In ... avoid colds. There is no cure for the common cold. For relief, try Getting plenty of rest Drinking ...

  15. Familial Risk for Exceptional Longevity

    PubMed Central

    Sebastiani, Paola; Andersen, Stacy L.; McIntosh, Avery I.; Nussbaum, Lisa; Stevenson, Meredith D.; Pierce, Leslie; Xia, Samantha; Salance, Kelly; Perls, Thomas T.

    2015-01-01

    One of the most glaring deficiencies in the current assessment of mortality risk is the lack of information concerning the impact of familial longevity. In this work, we update estimates of sibling relative risk of living to extreme ages using data from more than 1,700 sibships, and we begin to examine the trend for heritability for different birth-year cohorts. We also build a network model that can be used to compute the increased chance for exceptional longevity of a subject, conditional on his family history of longevity. The network includes familial longevity from three generations and can be used to understand the effects of paternal and maternal longevity on an individual's chance to live to an extreme age. PMID:27041978

  16. Familial Risk for Exceptional Longevity.

    PubMed

    Sebastiani, Paola; Andersen, Stacy L; McIntosh, Avery I; Nussbaum, Lisa; Stevenson, Meredith D; Pierce, Leslie; Xia, Samantha; Salance, Kelly; Perls, Thomas T

    2016-01-01

    One of the most glaring deficiencies in the current assessment of mortality risk is the lack of information concerning the impact of familial longevity. In this work, we update estimates of sibling relative risk of living to extreme ages using data from more than 1,700 sibships, and we begin to examine the trend for heritability for different birth-year cohorts. We also build a network model that can be used to compute the increased chance for exceptional longevity of a subject, conditional on his family history of longevity. The network includes familial longevity from three generations and can be used to understand the effects of paternal and maternal longevity on an individual's chance to live to an extreme age.

  17. Chiral exceptional points in metasurfaces

    NASA Astrophysics Data System (ADS)

    Kang, Ming; Chen, Jing; Chong, Y. D.

    2016-09-01

    An exceptional point (EP) is a degeneracy occurring in a non-energy-conserving system, in which two eigenvectors of a non-Hermitian Hamiltonian coalesce. We explore how EPs can be realized in a metamaterial surface, or metasurface, consisting of a pair of lossy coupled linear antennas in each unit cell. EPs appear in the eigenvectors of the transmission matrix by tuning the frequency and the coupling and loss rates of the metasurface. Each EP is associated with the appearance of a circularly polarized transmission eigenstate; hence, within the parameter space of the system, the EPs lie along pairs of curves with distinct chirality. Our results are obtained using finite-difference time-domain simulations, as well as a fitted coupled-mode theory. The coupled-mode theory agrees well with the numerical results and is capable of accurately predicting the EP f curves.

  18. Major depression

    MedlinePlus

    Depression - major; Depression - clinical; Clinical depression; Unipolar depression; Major depressive disorder ... providers do not know the exact causes of depression. It is believed that chemical changes in the ...

  19. Common cold

    MedlinePlus

    ... this page: //medlineplus.gov/ency/article/000678.htm Common cold To use the sharing features on this page, please enable JavaScript. The common cold most often causes a runny nose, nasal congestion, ...

  20. 45 CFR 148.220 - Excepted benefits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... income insurance. (3) Liability insurance, including general liability insurance and automobile liability... insurance. (6) Automobile medical payment insurance. (7) Credit-only insurance (for example, mortgage... FOR THE INDIVIDUAL HEALTH INSURANCE MARKET Preemption; Excepted Benefits § 148.220 Excepted...

  1. 48 CFR 1325.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOREIGN ACQUISITION Buy American Act-Supplies 1325.103 Exceptions. (a) The designee authorized to make a... has an agreement with a foreign government providing a blanket exception to the Buy America Act is...

  2. Identifying Twice Exceptional Children: A Toolkit for Success

    ERIC Educational Resources Information Center

    Rizza, Mary G.; Morrison, William F.

    2007-01-01

    Students identified as gifted who also display one or more areas of disability remain under-identified both in special and gifted education programs. All too often school personnel do not have the resources necessary to make decisions about this unique group of students commonly called the twice-exceptional. The purpose of this article is to…

  3. Clays, common

    USGS Publications Warehouse

    Virta, R.L.

    1998-01-01

    Part of a special section on the state of industrial minerals in 1997. The state of the common clay industry worldwide for 1997 is discussed. Sales of common clay in the U.S. increased from 26.2 Mt in 1996 to an estimated 26.5 Mt in 1997. The amount of common clay and shale used to produce structural clay products in 1997 was estimated at 13.8 Mt.

  4. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  5. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  6. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  7. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  8. 7 CFR 773.23 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Exception. 773.23 Section 773.23 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to...

  9. 22 CFR 126.3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Exceptions. 126.3 Section 126.3 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS § 126.3 Exceptions. In a case of exceptional or undue hardship, or when it is otherwise in the...

  10. 22 CFR 126.3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Exceptions. 126.3 Section 126.3 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS § 126.3 Exceptions. In a case of exceptional or undue hardship, or when it is otherwise in the...

  11. 22 CFR 126.3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Exceptions. 126.3 Section 126.3 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS § 126.3 Exceptions. In a case of exceptional or undue hardship, or when it is otherwise in the...

  12. 22 CFR 126.3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Exceptions. 126.3 Section 126.3 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS § 126.3 Exceptions. In a case of exceptional or undue hardship, or when it is otherwise in the...

  13. Technology Applications for the Exceptional Learner.

    ERIC Educational Resources Information Center

    Burke, Janet

    This paper is a series of lesson plans designed to assist teachers with the instruction of the exceptional learner. The focus is on identifying what the exceptional learner needs, and provides specific lesson plans that met those needs. Exceptional learners experience difficulty with spelling, organization, and metacognition. Detailed directions…

  14. 15 CFR 30.62 - Emergency exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Emergency exceptions. 30.62 Section 30.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS... exceptions. The Census Bureau and CBP may jointly authorize the postponement of or exception to...

  15. 15 CFR 30.62 - Emergency exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Emergency exceptions. 30.62 Section 30.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS... exceptions. The Census Bureau and CBP may jointly authorize the postponement of or exception to...

  16. 15 CFR 30.62 - Emergency exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Emergency exceptions. 30.62 Section 30.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS... exceptions. The Census Bureau and CBP may jointly authorize the postponement of or exception to...

  17. 15 CFR 30.62 - Emergency exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Emergency exceptions. 30.62 Section 30.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS... exceptions. The Census Bureau and CBP may jointly authorize the postponement of or exception to...

  18. 15 CFR 30.62 - Emergency exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Emergency exceptions. 30.62 Section 30.62 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS... exceptions. The Census Bureau and CBP may jointly authorize the postponement of or exception to...

  19. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  20. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  1. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  2. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  3. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  4. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  5. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  6. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  7. 45 CFR 670.7 - Food exception.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Food exception. 670.7 Section 670.7 Public Welfare... ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.7 Food exception. Paragraph (e) of § 670.4 shall not apply to the introduction of animals and plants into Antarctica for use as food as long as animals...

  8. 22 CFR 506.7 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Exceptions. 506.7 Section 506.7 Foreign Relations BROADCASTING BOARD OF GOVERNORS PART-TIME CAREER EMPLOYMENT PROGRAM § 506.7 Exceptions. The Director of the Board and the Associate Director for Management may except positions from inclusion in...

  9. The Exceptional Adolescent: A Bibliography for Psychology and Education.

    ERIC Educational Resources Information Center

    McMurray, J. G.

    Presented is a bibliography of Journal articles printed in English and published since 1970 on the psychology and education of the exceptional adolescent. Entries are divided into six major sections (subdivisions are in parentheses): general (background reading, technology, management, mental health, curriculum, counseling, etc.), intellectual…

  10. Student Commons

    ERIC Educational Resources Information Center

    Gordon, Douglas

    2010-01-01

    Student commons are no longer simply congregation spaces for students with time on their hands. They are integral to providing a welcoming environment and effective learning space for students. Many student commons have been transformed into spaces for socialization, an environment for alternative teaching methods, a forum for large group meetings…

  11. A 2014 nationwide survey of the distribution of Soybean mosaic virus (SMV), Soybean yellow mottle mosaic virus (SYMMV) and Soybean yellow common mosaic virus (SYCMV) major viruses in South Korean soybean fields, and changes

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 2014 symptomatic soybean samples were collected throughout Korea, and were tested for the most important soybean viruses found in Korea, namely Soybean mosaic virus (SMV), Soybean yellow common mosaic virus (SYCMV), and Soybean yellow mottle mosaic virus (SYMMV). SYMMV was most commonly detected,...

  12. QCI Common

    SciTech Connect

    McCaskey, Alexander J.

    2016-11-18

    There are many common software patterns and utilities for the ORNL Quantum Computing Institute that can and should be shared across projects. Otherwise we find duplication of code which adds unwanted complexity. This is a software product seeks to alleviate this by providing common utilities such as object factories, graph data structures, parameter input mechanisms, etc., for other software products within the ORNL Quantum Computing Institute. This work enables pure basic research, has no export controlled utilities, and has no real commercial value.

  13. A Year of Exceptional Achievements FY 2008

    SciTech Connect

    devore, L; Chrzanowski, P

    2008-11-06

    2008 highlights: (1) Stockpile Stewardship and Complex Transformation - LLNL achieved scientific breakthroughs that explain some of the key 'unknowns' in nuclear weapons performance and are critical to developing the predictive science needed to ensure the safety, reliability, and security of the U.S. nuclear deterrent without nuclear testing. In addition, the National Ignition Facility (NIF) passed 99 percent completion, an LLNL supercomputer simulation won the 2007 Gordon Bell Prize, and a significant fraction of our inventory of special nuclear material was shipped to other sites in support of complex transformation. (2) National and Global Security - Laboratory researchers delivered insights, technologies, and operational capabilities that are helping to ensure national security and global stability. Of particular note, they developed advanced detection instruments that provide increased speed, accuracy, specificity, and resolution for identifying and characterizing biological, chemical, nuclear, and high-explosive threats. (3) Exceptional Science and Technology - The Laboratory continued its tradition of scientific excellence and technical innovation. LLNL scientists made significant contributions to Nobel Prize-winning work on climate change. LLNL also received three R&D 100 awards and six Nanotech 50 awards, and dozens of Laboratory scientists and engineers were recognized with professional awards. These honors provide valuable confirmation that peers and outside experts recognize the quality of our staff and our work. (4) Enhanced Business and Operations - A major thrust under LLNS is to make the Laboratory more efficient and cost competitive. We achieved roughly $75 million in cost savings for support activities through organizational changes, consolidation of services, improved governance structures and work processes, technology upgrades, and systems shared with Los Alamos National Laboratory. We realized nonlabor cost savings of $23 million. Severe

  14. Circulating leptin and adiponectin concentrations in healthy exceptional longevity.

    PubMed

    Pareja-Galeano, Helios; Santos-Lozano, Alejandro; Sanchis-Gomar, Fabian; Fiuza-Luces, Carmen; Garatachea, Nuria; Gálvez, Beatriz G; Lucia, Alejandro; Emanuele, Enzo

    2017-03-01

    People reaching exceptional longevity free of major age-related diseases represent the paradigm of successful aging. Adipose tissue function declines as we age, potentially resulting in changes of circulating adipokines (e.g., leptin and adiponectin). Here, we measured circulating levels of leptin and adiponectin in healthy centenarians (n=81; 100-104 years) and younger elderly controls (n=46; 70-80 years). Centenarians had significant higher serum levels of leptin compared with controls (p<0.001), whereas no significant differences were observed for adiponectin. Further research including also other blood variables will be needed to elucidate whether high leptin levels could serve as a hallmark of healthy exceptional longevity.

  15. Major appliance management report

    SciTech Connect

    Robertson, M.; O`Donnell, K.F.

    1990-07-15

    Major appliances (also called `white goods`) have long been managed as part of the traditional municipal solid waste (MSW) stream, with the most common management method being landfill disposal. Over the past several years, it has become increasingly apparent that major appliances are not easily or best managed along with MSW. Indiscriminate disposal of major appliances can cause environmental problems and unnecessary use of scarce landfill space as well as wasting valuable recyclable materials. In recognition of these factors, the 1989 Minnesota Legislature took a number of steps to shift the management of major appliances towards separate handling and recycling.

  16. Major Links.

    ERIC Educational Resources Information Center

    Henderson, Tona

    1995-01-01

    Provides electronic mail addresses for resources and discussion groups related to the following academic majors: art, biology, business, chemistry, computer science, economics, health sciences, history, literature, math, music, philosophy, political science, psychology, sociology, and theater. (AEF)

  17. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  18. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  19. 2 CFR 176.80 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and...

  20. 2 CFR 176.80 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Exceptions. 176.80 Section 176.80 Grants and... project. (2) Unreasonable cost. The head of the Federal department or agency may determine that the cost... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and...

  1. 2 CFR 176.80 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and...

  2. 45 CFR 1226.9 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Exceptions. 1226.9 Section 1226.9 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE PROHIBITIONS ON ELECTORAL AND LOBBYING ACTIVITIES Volunteer Activities § 1226.9 Exceptions. (a) A volunteer...

  3. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Exceptions. 82.2 Section 82.2 Money and Finance: Treasury Regulations Relating to Money and Finance MONETARY OFFICES, DEPARTMENT OF THE TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in §...

  4. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  5. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  6. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  7. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  8. 8 CFR 286.3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Exceptions. 286.3 Section 286.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS IMMIGRATION USER FEE § 286.3 Exceptions. The fees set forth in §§ 286.2(a) and 286.2(b) shall not be charged or collected from passengers...

  9. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Exception authority. 1779.17 Section 1779.17 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority....

  10. 39 CFR 3055.3 - Reporting exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Reporting exceptions. 3055.3 Section 3055.3 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL SERVICE PERFORMANCE AND CUSTOMER SATISFACTION REPORTING Annual Reporting of Service Performance Achievements § 3055.3 Reporting exceptions. (a) The...

  11. 48 CFR 2903.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts With Government Employees or Organizations Owned or... compelling reason to do so, is the Assistant Secretary for Administration and Management authorized to except... Assistant Secretary for Administration and Management may unilaterally approve an exception. The...

  12. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging exceptions. 173.63 Section 173.63... SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1 § 173.63 Packaging exceptions... which are used to project fastening devices. (2) Packaging for cartridges, small arms, and...

  13. 7 CFR 1955.81 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exception authority. 1955.81 Section 1955.81 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) PROPERTY MANAGEMENT Management of Property § 1955.81 Exception...

  14. 45 CFR 148.220 - Excepted benefits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... insurance laws; (ii) For qualified long-term care insurance services, as defined in section 7702B(c)(1) of... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE INDIVIDUAL HEALTH INSURANCE MARKET Preemption; Excepted Benefits § 148.220 Excepted...

  15. 2 CFR 176.80 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Exceptions. 176.80 Section 176.80 Grants and... manufactured goods needed in the project. (2) Unreasonable cost. The head of the Federal department or agency... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and...

  16. 2 CFR 176.80 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Exceptions. 176.80 Section 176.80 Grants and... project. (2) Unreasonable cost. The head of the Federal department or agency may determine that the cost... manufactured goods may be used— (1) The award official shall list the excepted materials in the award; and...

  17. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for Spacelab Services § 1214.807 Exceptional payloads. Customers whose payloads qualify under the...

  18. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for Spacelab Services § 1214.807 Exceptional payloads. Customers whose payloads qualify under the...

  19. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for Spacelab Services § 1214.807 Exceptional payloads. Customers whose payloads qualify under the...

  20. 14 CFR 1214.807 - Exceptional payloads.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Exceptional payloads. 1214.807 Section 1214.807 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement for Spacelab Services § 1214.807 Exceptional payloads. Customers whose payloads qualify under the...

  1. 7 CFR 1782.22 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Exception authority. 1782.22 Section 1782.22 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) SERVICING OF WATER AND WASTE PROGRAMS § 1782.22 Exception authority. The...

  2. 42 CFR 1001.952 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Exceptions. 1001.952 Section 1001.952 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG AUTHORITIES PROGRAM INTEGRITY-MEDICARE AND STATE HEALTH CARE PROGRAMS Permissive Exclusions § 1001.952 Exceptions. The following payment practices shall not...

  3. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions....

  4. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions....

  5. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions....

  6. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions....

  7. 48 CFR 39.204 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 39.204 Section 39.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions....

  8. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  9. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  10. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  11. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  12. 28 CFR 63.9 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Exception. 63.9 Section 63.9 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FLOODPLAIN MANAGEMENT AND WETLAND PROTECTION PROCEDURES § 63.9 Exception. Nothing in these guidelines shall apply to assistance provided for emergency work essential...

  13. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  14. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  15. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  16. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  17. 7 CFR 503.15 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Exceptions. 503.15 Section 503.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON PLUM ISLAND ANIMAL DISEASE CENTER § 503.15 Exceptions. The Director, PIADC, may,...

  18. 42 CFR 412.348 - Exception payments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... total estimated payments under the exception process not exceed 10 percent of the total estimated...) of this section. (e) Determining a hospital's exception payment amount—(1) Cumulative comparison. For... requirement specified in paragraph (h) of this section that total estimated payments under the...

  19. 21 CFR 1316.66 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exceptions. 1316.66 Section 1316.66 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Hearings § 1316.66 Exceptions. (a) Within twenty days after the date upon which...

  20. Twice Exceptionality from a Practitioner's Perspective

    ERIC Educational Resources Information Center

    Omdal, Stuart

    2015-01-01

    The new definition of twice exceptionality by the National Twice-Exceptional Community of Practice (2e CoP) is a tool that will facilitate communication and collaboration for practitioners in the regular classroom, gifted education specialists, administrators, and professors. In this article, the author shares his experiences in several of these…

  1. 45 CFR 148.220 - Excepted benefits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and automobile liability insurance. (4) Coverage issued as a supplement to liability insurance. (5) Workers' compensation or similar insurance. (6) Automobile medical payment insurance. (7) Credit-only... FOR THE INDIVIDUAL HEALTH INSURANCE MARKET Preemption; Excepted Benefits § 148.220 Excepted...

  2. 45 CFR 1226.9 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the State Director on a quarterly basis of all activity occurring pursuant to this exception. (2) The... ON ELECTORAL AND LOBBYING ACTIVITIES Volunteer Activities § 1226.9 Exceptions. (a) A volunteer may... addressed. (3) The volunteer or the program sponsor provides a copy of such request to the State...

  3. 45 CFR 1226.9 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the State Director on a quarterly basis of all activity occurring pursuant to this exception. (2) The... ON ELECTORAL AND LOBBYING ACTIVITIES Volunteer Activities § 1226.9 Exceptions. (a) A volunteer may... addressed. (3) The volunteer or the program sponsor provides a copy of such request to the State...

  4. 45 CFR 1226.9 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the State Director on a quarterly basis of all activity occurring pursuant to this exception. (2) The... ON ELECTORAL AND LOBBYING ACTIVITIES Volunteer Activities § 1226.9 Exceptions. (a) A volunteer may... addressed. (3) The volunteer or the program sponsor provides a copy of such request to the State...

  5. 45 CFR 1226.9 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the State Director on a quarterly basis of all activity occurring pursuant to this exception. (2) The... ON ELECTORAL AND LOBBYING ACTIVITIES Volunteer Activities § 1226.9 Exceptions. (a) A volunteer may... addressed. (3) The volunteer or the program sponsor provides a copy of such request to the State...

  6. 38 CFR 1.897 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Exceptions. 1.897 Section 1.897 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Part-Time Career Employment Program § 1.897 Exceptions. The Secretary of Veterans Affairs, or designees,...

  7. 24 CFR 300.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Exceptions. 300.15 Section 300.15 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) GOVERNMENT NATIONAL MORTGAGE ASSOCIATION, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT GENERAL § 300.15 Exceptions....

  8. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Exception provision. 513.215 Section 513.215 Foreign Relations BROADCASTING BOARD OF GOVERNORS GOVERNMENT DEBARMENT AND SUSPENSION (NONPROCUREMENT) AND GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision....

  9. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Exception provision. 513.215 Section 513.215 Foreign Relations BROADCASTING BOARD OF GOVERNORS GOVERNMENT DEBARMENT AND SUSPENSION (NONPROCUREMENT) AND GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision....

  10. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Exception provision. 513.215 Section 513.215 Foreign Relations BROADCASTING BOARD OF GOVERNORS GOVERNMENT DEBARMENT AND SUSPENSION (NONPROCUREMENT) AND GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision....

  11. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Exception provision. 513.215 Section 513.215 Foreign Relations BROADCASTING BOARD OF GOVERNORS GOVERNMENT DEBARMENT AND SUSPENSION (NONPROCUREMENT) AND GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision....

  12. 22 CFR 513.215 - Exception provision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Exception provision. 513.215 Section 513.215 Foreign Relations BROADCASTING BOARD OF GOVERNORS GOVERNMENT DEBARMENT AND SUSPENSION (NONPROCUREMENT) AND GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.215 Exception provision....

  13. 45 CFR 1216.1-4 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Exceptions. 1216.1-4 Section 1216.1-4 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE NONDISPLACEMENT OF EMPLOYED WORKERS AND NONIMPAIRMENT OF CONTRACTS FOR SERVICE § 1216.1-4 Exceptions. (a) The requirements of § 1216.1-3 are...

  14. The Doubly Exceptional Child: A Principal's Dilemma.

    ERIC Educational Resources Information Center

    Kesner, Rebecca J., Ed.

    2002-01-01

    This document contains two articles concerned with doubly exceptional children and gifted education. In "The Doubly Exceptional Child: A Principal's Dilemma," (Carol J. Mills and Linda E. Brody), such children do not fit into the usual categories for sorting children because their gifts and disabilities often mask each other. Suggestions are…

  15. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $204,000, the exception for unreasonable cost may apply (see FAR...

  16. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $202,000, the exception for unreasonable cost may apply (see FAR...

  17. 48 CFR 225.7017-3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... to utilize domestic photovoltaic devices in covered contracts, with the following exceptions: (a) Qualifying country. Qualifying country photovoltaic devices may be utilized in any covered contract, because... photovoltaic devices valued at less than $202,000, the exception for unreasonable cost may apply (see FAR...

  18. 48 CFR 925.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 925.103 Section 925.103 Federal Acquisition Regulations System DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 925.103 Exceptions. (a) Contracting officers may make the...

  19. 48 CFR 825.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 825.103 Section 825.103 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 825.103 Exceptions. (a) Public interest. When...

  20. 48 CFR 1425.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 1425.103 Section 1425.103 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 1425.103 Exceptions. (a) The AS/PMB is authorized to...

  1. 14 CFR 34.9 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES General Provisions § 34.9 Exceptions... exception allows production of an engine for installation on an in-service aircraft. A spare engine may not... certificated to meet all applicable requirements. (3) A spare engine may be used only when the emissions of...

  2. 14 CFR 34.9 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES General Provisions § 34.9 Exceptions... exception allows production of an engine for installation on an in-service aircraft. A spare engine may not... certificated to meet all applicable requirements. (3) A spare engine may be used only when the emissions of...

  3. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  4. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  5. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  6. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  7. 47 CFR 2.807 - Statutory exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Statutory exceptions. 2.807 Section 2.807 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND RADIO TREATY MATTERS; GENERAL RULES AND REGULATIONS Marketing of Radio-frequency Devices § 2.807 Statutory exceptions. As provided...

  8. 32 CFR 536.45 - Statutory exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Statutory exceptions. 536.45 Section 536.45 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES Investigation and Processing of Claims § 536.45 Statutory exceptions. This topic is more fully discussed in DA Pam...

  9. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  10. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  11. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  12. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  13. 48 CFR 425.103 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Exceptions. 425.103 Section 425.103 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 425.103 Exceptions. (a) The Senior Procurement...

  14. 39 CFR 310.3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... fall under this exception. (d) Special messenger. (1) The use of a special messenger employed for the.... The permission granted under this exception is restricted to use of messenger service on an infrequent, irregular basis by the sender or addressee of the message. (2) A special messenger is a person who, at...

  15. 39 CFR 310.3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... fall under this exception. (d) Special messenger. (1) The use of a special messenger employed for the.... The permission granted under this exception is restricted to use of messenger service on an infrequent, irregular basis by the sender or addressee of the message. (2) A special messenger is a person who, at...

  16. 39 CFR 310.3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... fall under this exception. (d) Special messenger. (1) The use of a special messenger employed for the.... The permission granted under this exception is restricted to use of messenger service on an infrequent, irregular basis by the sender or addressee of the message. (2) A special messenger is a person who, at...

  17. 39 CFR 310.3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... fall under this exception. (d) Special messenger. (1) The use of a special messenger employed for the.... The permission granted under this exception is restricted to use of messenger service on an infrequent, irregular basis by the sender or addressee of the message. (2) A special messenger is a person who, at...

  18. 39 CFR 310.3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... fall under this exception. (d) Special messenger. (1) The use of a special messenger employed for the.... The permission granted under this exception is restricted to use of messenger service on an infrequent, irregular basis by the sender or addressee of the message. (2) A special messenger is a person who, at...

  19. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Exceptions. 82.2 Section 82.2 Money and Finance: Treasury Regulations Relating to Money and Finance MONETARY OFFICES, DEPARTMENT OF THE TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in §...

  20. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Exceptions. 82.2 Section 82.2 Money and Finance: Treasury Regulations Relating to Money and Finance MONETARY OFFICES, DEPARTMENT OF THE TREASURY 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in §...

  1. 24 CFR 91.20 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Exceptions. 91.20 Section 91.20 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development CONSOLIDATED SUBMISSIONS FOR COMMUNITY PLANNING AND DEVELOPMENT PROGRAMS General § 91.20 Exceptions. The...

  2. 38 CFR 1.897 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Exceptions. 1.897 Section 1.897 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Part-Time Career Employment Program § 1.897 Exceptions. The Secretary of Veterans Affairs, or designees,...

  3. 38 CFR 1.897 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Exceptions. 1.897 Section 1.897 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Part-Time Career Employment Program § 1.897 Exceptions. The Secretary of Veterans Affairs, or designees,...

  4. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  5. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  6. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  7. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  8. 40 CFR 262.55 - Exception reports.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Exception reports. 262.55 Section 262.55 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception...

  9. 31 CFR 82.2 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Exceptions. 82.2 Section 82.2 Money and Finance: Treasury Regulations Relating to Money and Finance 5-CENT AND ONE-CENT COIN REGULATIONS § 82.2 Exceptions. (a) The prohibition contained in § 82.1 against the exportation of 5-cent coins...

  10. 48 CFR 1503.602 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Exceptions. 1503.602 Section 1503.602 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY GENERAL IMPROPER... shall consult with the Designated Agency Ethics Official before authorizing any exceptions....

  11. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  12. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  13. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  14. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  15. 7 CFR 501.15 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Exceptions. 501.15 Section 501.15 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL RESEARCH SERVICE, DEPARTMENT OF AGRICULTURE CONDUCT ON U.S. MEAT ANIMAL RESEARCH CENTER, CLAY CENTER, NEBRASKA § 501.15 Exceptions....

  16. 7 CFR 4280.104 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Exception authority. 4280.104 Section 4280.104 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND... Efficiency Improvements Program § 4280.104 Exception authority. The Administrator may, on a...

  17. Common clay and shale

    USGS Publications Warehouse

    Virta, R.L.

    2006-01-01

    At present, 150 companies produce common clay and shale in 41 US states. According to the United States Geological Survey (USGS), domestic production in 2005 reached 24.8 Mt valued at $176 million. In decreasing order by tonnage, the leading producer states include North Carolina, Texas, Alabama, Georgia and Ohio. For the whole year, residential and commercial building construction remained the major market for common clay and shale products such as brick, drain tile, lightweight aggregate, quarry tile and structural tile.

  18. Occurrance in Korea of three major soybean viruses, Soybean mosaic virus (SMV), Soybean yellow mottle mosaic virus (SYCMV), and Soybean yellow common mosaic virus (SYCMV) revealed by a nationwide survey of soybean fields

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soybean yellow mottle mosaic virus (SYMMV) and soybean yellow common mosaic virus (SYCMV) were recently isolated in Korea, and it hasn’t been reported how these two viruses were dispersed in Korea. In 2012, we performed a nationwide survey of subsistence soybean farms in Korea. Leaves that appeared ...

  19. The Exception Does Not Rule: Attention Constrains Form Preparation in Word Production

    PubMed Central

    O’Séaghdha, Pádraig G.; Frazer, Alexandra K.

    2014-01-01

    Form preparation in word production, the benefit of exploiting a useful common sound (such as the first phoneme) of iteratively spoken small groups of words, is notoriously fastidious, exhibiting a seemingly categorical, all-or-none character, and a corresponding susceptibility to ‘killers’ of preparation. In particular, the presence of a single exception item in a group of otherwise phonologically consistent words has been found to eliminate the benefit of knowing a majority characteristic. This has been interpreted to mean that form preparation amounts to partial production, and thus provides a window on fundamental processes of phonological word encoding (e.g., Levelt et al., 1999). However, preparation of only fully distributed properties appears to be non-optimal, and is difficult to reconcile with the sensitivity of cognitive responses to probabilities in other domains. We show here that the all-or-none characteristic of form preparation is specific to task format. Preparation for sets that included an exception item occurred in ecologically valid production tasks, picture naming (Experiment 1), and word naming (Experiment 2). Preparation failed only in the commonly used, but indirect and resource-intensive, associative cuing task (Experiment 3). We outline an account of form preparation in which anticipation of word-initial phonological fragments uses a limited capacity, sustained attentional capability that points to rather than enacts possibilities for imminent speech. PMID:24548328

  20. Making the Common Good Common

    ERIC Educational Resources Information Center

    Chase, Barbara

    2011-01-01

    How are independent schools to be useful to the wider world? Beyond their common commitment to educate their students for meaningful lives in service of the greater good, can they educate a broader constituency and, thus, share their resources and skills more broadly? Their answers to this question will be shaped by their independence. Any…

  1. Major Andre

    ERIC Educational Resources Information Center

    Henisch, B. A.; Henisch, H. K.

    1976-01-01

    If most Revolutionary era people seem two-dimensional their lives simpler to understand than ours, it may be only that history, with the benefit of hindsight, clarifies. Examines a profile of Major John Andre, the British liaison officer in Benedict Arnold's plan to surrender West Point, as both hero and villain to show the complexity of early…

  2. Exceptional supergravity theories and the magic square

    NASA Astrophysics Data System (ADS)

    Günaydin, M.; Sierra, G.; Townsend, P. K.

    1983-12-01

    We derive the magic square of Freudenthal, Rozenfeld, and Tits from the geometry of a special class of N=2 Maxwell-Einstein supergravity theories. We also show that all of these theories are obtainable by truncation of N=8 supergravity theories in various spacetime dimensions d, except for an ``exceptional'' subclass, unique for a given d, which is associated with with the exceptional Jordan algebra of 3 × 3 hermitian octonionic matrices. Laboratoire Propre du Centre National de la Recherche Scientifique, associé à l'Ecole Normale Supérieure et à l'Université de Paris-Sud.

  3. Common clay and shale

    USGS Publications Warehouse

    Virta, R.L.

    2001-01-01

    Part of the 2000 annual review of the industrial minerals sector. A general overview of the common clay and shale industry is provided. In 2000, U.S. production increased by 5 percent, while sales or use declined to 23.6 Mt. Despite the slowdown in the economy, no major changes are expected for the market.

  4. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  5. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  6. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  7. 15 CFR 905.5 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... PROCEEDINGS OF INFORMATION COLLECTED BY VOLUNTARY FISHERY DATA COLLECTORS § 905.5 Exceptions. The provisions... person; or (b) Impairment or interference with the duties of a voluntary fishery data collector....

  8. 15 CFR 905.5 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... PROCEEDINGS OF INFORMATION COLLECTED BY VOLUNTARY FISHERY DATA COLLECTORS § 905.5 Exceptions. The provisions... person; or (b) Impairment or interference with the duties of a voluntary fishery data collector....

  9. 15 CFR 905.5 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROCEEDINGS OF INFORMATION COLLECTED BY VOLUNTARY FISHERY DATA COLLECTORS § 905.5 Exceptions. The provisions... person; or (b) Impairment or interference with the duties of a voluntary fishery data collector....

  10. 15 CFR 905.5 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROCEEDINGS OF INFORMATION COLLECTED BY VOLUNTARY FISHERY DATA COLLECTORS § 905.5 Exceptions. The provisions... person; or (b) Impairment or interference with the duties of a voluntary fishery data collector....

  11. 15 CFR 905.5 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... PROCEEDINGS OF INFORMATION COLLECTED BY VOLUNTARY FISHERY DATA COLLECTORS § 905.5 Exceptions. The provisions... person; or (b) Impairment or interference with the duties of a voluntary fishery data collector....

  12. 33 CFR 175.115 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SAFETY EQUIPMENT REQUIREMENTS Visual Distress Signals § 175.115 Exceptions. The following persons need not comply with § 175.110; however, each must carry on board visual distress signals suitable...

  13. 32 CFR 811.1 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SALE OF VISUAL INFORMATION MATERIALS § 811.1 Exceptions. The regulations in this part do not apply to: (a) Visual information (VI) materials made for the Air Force Office of Special Investigations for...

  14. The Exceptional Environment: Strategies for Design

    ERIC Educational Resources Information Center

    Spivack, Mayer

    1974-01-01

    Author addressed himself to the problem of designing effective environments for exceptional children. He developed essential "polar paradigms" for the observation of children's behavior in relation to their physical setting. (Editor/RK)

  15. 44 CFR 206.345 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... actions essential to the saving of lives and the protection of property and the public health and safety... facilities, except as provided in § 206.347(c)(5); (3) Repair of air and water navigation aids and...

  16. 44 CFR 206.345 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... actions essential to the saving of lives and the protection of property and the public health and safety... facilities, except as provided in § 206.347(c)(5); (3) Repair of air and water navigation aids and...

  17. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  18. 48 CFR 8.503 - Exception.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of Helium 8.503 Exception. The requirements of this subpart do not apply to contracts or subcontracts in which the helium was acquired by the contractor...

  19. 7 CFR 1782.22 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE (CONTINUED) SERVICING OF WATER AND WASTE PROGRAMS § 1782.22 Exception authority. The Administrator... inconsistent with the authorizing statute or other applicable law and is determined to be in the...

  20. 7 CFR 1780.25 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS General Policies and Requirements § 1780.25 Exception... this part which is not inconsistent with the authorizing statute or other applicable law and...

  1. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority. The... not inconsistent with the authorizing statute or other applicable law and is determined to be in...

  2. 7 CFR 1779.17 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE (CONTINUED) WATER AND WASTE DISPOSAL PROGRAMS GUARANTEED LOANS § 1779.17 Exception authority. The... not inconsistent with the authorizing statute or other applicable law and is determined to be in...

  3. 48 CFR 9.304 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification... would meet the requirements without testing and approval....

  4. 48 CFR 9.304 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification... would meet the requirements without testing and approval....

  5. 48 CFR 9.304 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification... would meet the requirements without testing and approval....

  6. 48 CFR 9.304 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification... would meet the requirements without testing and approval....

  7. 48 CFR 9.304 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification... would meet the requirements without testing and approval....

  8. 48 CFR 225.103 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... interest exceptions for certain countries are in 225.872. (B) For procurements covered by the World Trade Organization Government Procurement Agreement, the Under Secretary of Defense (Acquisition, Technology,...

  9. 48 CFR 225.103 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... interest exceptions for certain countries are in 225.872. (B) For procurements covered by the World Trade Organization Government Procurement Agreement, the Under Secretary of Defense (Acquisition, Technology,...

  10. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  11. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  12. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  13. 31 CFR 101.7 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... TREASURY MITIGATION OF FORFEITURE OF COUNTERFEIT GOLD COINS § 101.7 Exceptions. The provisions of this part shall not apply where the cost of smelting the gold coins exceeds the value of the gold bullion to...

  14. THE CONCEPT OF EXCEPTIONALITY: A LEGAL FARCE?

    PubMed Central

    Ford, Amy

    2012-01-01

    How do we decide which treatments should be offered by the National Health Service (NHS) when we cannot afford to fund them all? In the absence of a positive appraisal by the National Institute for Health and Clinical Excellence (NICE), which mandates the provision of a treatment by the NHS, Primary Care Trusts (PCTs) are free to decide whether to provide a particular drug to some, or all, of their population. However, as public bodies, it is a well-established principle of Administrative Law that PCTs are not at liberty to fetter the exercise of their own discretion. They must recognise the possibility that some patients will have exceptional circumstances, and as a consequence, any general policy prohibiting the funding of a drug cannot be absolute. In the absence of statutory guidance on what might constitute exceptional, clinicians are left guessing as to whether their patients might be eligible for funding on the grounds of exceptionality. Using the context of expensive cancer drugs, I will examine the concept of exceptionality from clinical, moral, and legal perspectives, focussing particularly on the role of social factors in determining exceptionality. I will review the cases where PCTs' decisions not to fund cancer drugs were subject to legal action and argue that the courts have provided little guidance on interpreting the term exceptional, and that the concept has a limited role to play in the allocation of scarce health resources at a local level. PMID:22389444

  15. A Comparison of the Demographics, Clinical Features, and Survival of Patients with Adenoid Cystic Carcinoma of Major and Minor Salivary Glands Versus Less Common Sites within the SEER Registry

    PubMed Central

    Li, Nan; Xu, Li; Zhao, Hui; El-Naggar, Adel K.; Sturgis, Erich M.

    2012-01-01

    Objectives The scientific literature to date lacks population-based studies on the demographics, clinical features, and survival of patients with adenoid cystic carcinoma (ACC) of different anatomic sites. Methods We identified 5349 ACC cases in major salivary glands (N=1850), minor salivary glands (N=2077), breast (N=696), skin (N=291), lung and bronchus (N=203), female genital system (N=132), and eye and orbit (N=100) from the Surveillance, Epidemiology, and End Results (SEER) registry. Differences in demographics, clinical features, and survival of patients were assessed. Results ACC of the eye and orbit was associated with younger age at presentation (mean=49.9 years). ACC of the skin or breast tended to present with less aggressive prognostic features, while ACC of the lung and bronchus or eye and orbit tended to present with more aggressive prognostic features. In multivariate survival analysis of patients presenting with localized disease, patients with ACC of breast (HR=0.40) or skin (HR=0.40) had a significantly lower risk death than patients with ACC of major salivary glands, while patients with ACC of lung and bronchus (HR=3.72) or eye and orbit (HR=3.67) had a significantly higher risk. For patients presenting with regional disease, the only clear prognostic difference in multivariate analysis was that patients with ACC of skin did significantly better. Conclusions The demographics and clinical features of ACC differ by disease site. Site may be an important predictor of survival for patients presenting with localized disease but is less important for patients presenting with regional disease. PMID:22179977

  16. Syrtis Major

    NASA Technical Reports Server (NTRS)

    2002-01-01

    (Released 1 May 2002) The Science This image is from the region of Syrtis Major, which is dominated by a low-relief shield volcano. This area is believed to be an area of vigorous aeolian activity with strong winds in the east-west direction. The effects of these winds are observed as relatively bright streaks across the image, extending from topographic features such as craters. The brighter surface material probably indicates a smaller relative particle size in these areas, as finer particles have a higher albedo. The bright streaks seen off of craters are believed to have formed during dust storms. A raised crater rim can cause a reduction in the wind velocity directly behind it, which results in finer particles being preferentially deposited in this location. In the top half of the image, there is a large bright streak that crosses the entire image. There is no obvious topographic obstacle, therefore it is unclear whether it was formed in the same manner as described above. This image is located northwest of Nili Patera, a large caldera in Syrtis Major. Different flows from the caldera eruptions can be recognized as raised ridges, representing the edge of a flow lobe. The Story In the 17th century, Holland was in its Golden Age, a time of cultural greatness and immense political and economic influence in the world. In that time, lived a inquisitive person named Christian Huygens. As a boy, he loved to draw and to figure out problems in mathematics. As a man, he used these talents to make the first detailed drawings of the Martian surface - - only 50 years or so after Galileo first turned his telescope on Mars. Mars suddenly became something other than a small red dot in the sky. One of the drawings Huygens made was of a dark marking on the red planet's surface named Syrtis Major. Almost 350 years later, here we are with an orbiter that can show us this place in detail. Exploration lives! It's great we can study this area up close. In earlier periods of history

  17. Exceptional sets for nonuniformly expanding maps

    NASA Astrophysics Data System (ADS)

    Campos, Sara; Gelfert, Katrin

    2016-04-01

    Given a rational map of the Riemann sphere and a subset A of its Julia set, we study the A-exceptional set, that is, the set of points whose orbit does not accumulate at A. We prove that if the topological entropy of A is less than the topological entropy of the full system then the A-exceptional set has full topological entropy. Furthermore, if the Hausdorff dimension of A is smaller than the dynamical dimension of the system then the Hausdorff dimension of the A-exceptional set is larger than or equal to the dynamical dimension, with equality in the particular case when the dynamical dimension and the Hausdorff dimension coincide. We also discuss the case of a general conformal {{C}1+α} dynamical system and, in particular, certain multimodal interval maps on their Julia set.

  18. Amendments to excepted benefits. Final rules.

    PubMed

    2014-10-01

    This document contains final regulations that amend the regulations regarding excepted benefits under the Employee Retirement Income Security Act of 1974, the Internal Revenue Code (the Code), and the Public Health Service Act. Excepted benefits are generally exempt from the health reform requirements that were added to those laws by the Health Insurance Portability and Accountability Act and the Patient Protection and Affordable Care Act. In addition, eligibility for excepted benefits does not preclude an individual from eligibility for a premium tax credit under section 36B of the Code if an individual chooses to enroll in coverage under a Qualified Health Plan through an Affordable Insurance Exchange. These regulations finalize some but not all of the proposed rules with minor modifications; additional guidance on limited wraparound coverage is forthcoming.

  19. Syrtis Major

    NASA Technical Reports Server (NTRS)

    2002-01-01

    (Released 6 June 2002) The Science This image, located near the equator and 288W (72E), is near the southern edge of a low, broad volcanic feature called Syrtis Major. A close look at this image reveals a wrinkly texture that indicates a very rough surface that is associated with the lava flows that cover this region. On a larger scale, there are numerous bright streaks that trail topographic features such as craters. These bright streaks are in the wind shadows of the craters where dust that settles onto the surface is not as easily scoured away. It is important to note that these streaks are only bright in a relative sense to the surrounding image. Syrtis Major is one of the darkest regions on Mars and it is as dark as fresh basalt flows or dunes are on Earth. The Story Cool! It almost looks as if nature has 'painted' comets on the surface of Mars, using craters as comet cores and dust as streaky tails. Of course, that's just an illusion. As in many areas of Mars, the wind is behind the creation of such fantastic landforms. The natural phenomenon seen here gives this particular surface of Mars a very dynamic, fast-moving, almost luminous 'cosmic personality.' The bright, powdery-looking streaks of dust are in the 'wind shadows' of craters, where dust that settles onto the surface is not as easily scoured away. That's because the wind moves across the land in a particular direction, and a raised surface like the rim of a crater 'protects' dust from being completely blown away on the other side. The raised landforms basically act as a buffer. From the streaks seen above, you can tell the wind was blowing in a northeast to southwest direction. Why are the streaks so bright? Because they contrast with the really dark underlying terrain in this volcanic area of Mars. Syrtis Major is one of the darkest regions on Mars because it is made of basalt. Basalt is typically dark gray or black, and forms when a certain type of molten lava cools. The meaning of the word basalt

  20. Exceptional points in anisotropic planar microcavities

    NASA Astrophysics Data System (ADS)

    Richter, Steffen; Michalsky, Tom; Sturm, Chris; Rosenow, Bernd; Grundmann, Marius; Schmidt-Grund, Rüdiger

    2017-02-01

    Planar microcavities allow the control and manipulation of spin polarization, manifested in phenomena like the optical spin Hall effect due to the intrinsic polarization mode splitting. Here, we study a transparent microcavity with broken rotational symmetry, realized by aligning the optic axis of a uniaxial cavity material in the cavity plane, giving rise to exceptional points in the dispersion relation. These occur pairwise, are circularly polarized, and are cores of polarization vortices. The exceptional points are result of the non-Hermitian character of the system and are in close relationship to singular optic axes in absorptive biaxial systems.

  1. A geometric formulation of exceptional field theory

    NASA Astrophysics Data System (ADS)

    du Bosque, Pascal; Hassler, Falk; Lüst, Dieter; Malek, Emanuel

    2017-03-01

    We formulate the full bosonic SL(5) exceptional field theory in a coordinateinvariant manner. Thereby we interpret the 10-dimensional extended space as a manifold with SL(5) × ℝ +-structure. We show that the algebra of generalised diffeomorphisms closes subject to a set of closure constraints which are reminiscent of the quadratic and linear constraints of maximal seven-dimensional gauged supergravities, as well as the section condition. We construct an action for the full bosonic SL(5) exceptional field theory, even when the SL(5) × ℝ +-structure is not locally flat.

  2. Common Cause Failure Modes

    NASA Technical Reports Server (NTRS)

    Wetherholt, Jon; Heimann, Timothy J.; Anderson, Brenda

    2011-01-01

    High technology industries with high failure costs commonly use redundancy as a means to reduce risk. Redundant systems, whether similar or dissimilar, are susceptible to Common Cause Failures (CCF). CCF is not always considered in the design effort and, therefore, can be a major threat to success. There are several aspects to CCF which must be understood to perform an analysis which will find hidden issues that may negate redundancy. This paper will provide definition, types, a list of possible causes and some examples of CCF. Requirements and designs from NASA projects will be used in the paper as examples.

  3. CMU Common Lisp User’s Manual

    DTIC Science & Technology

    1992-07-01

    macro definitions or manual case analysis . Although most Common Lisp implementations support inlinp expan-inn, it herormes a mnor powerful tool with...other than the Jefault (:nearest) can cause unusual behavior, since it will affect rounding done by CoMMon Lisp system code as well as rounding in user...should cause traps. [ossible exceptions are :underflow. :overflow, :inexact, :invalid and :divide-by-zero. Initially all traps except : inexact ar

  4. 'A major lobbying effort to change and unify the excise structure in six Central American countries': How British American Tobacco influenced tax and tariff rates in the Central American Common Market

    PubMed Central

    2011-01-01

    Background Transnational tobacco companies (TTCs) may respond to processes of regional trade integration both by acting politically to influence policy and by reorganising their own operations. The Central American Common Market (CACM) was reinvigorated in the 1990s, reflecting processes of regional trade liberalisation in Latin America and globally. This study aimed to ascertain how British American Tobacco (BAT), which dominated the markets of the CACM, sought to influence policy towards it by member country governments and how the CACM process impacted upon BAT's operations. Methods The study analysed internal tobacco industry documents released as a result of litigation in the US and available from the online Legacy Tobacco Documents Library at http://legacy.library.ucsf.edu/. Documents were retrieved by searching the BAT collection using key terms in an iterative process. Analysis was based on an interpretive approach involving a process of attempting to understand the meanings of individual documents and relating these to other documents in the set, identifying the central themes of documents and clusters of documents, contextualising the documentary data, and choosing representative material in order to present findings. Results Utilising its multinational character, BAT was able to act in a coordinated way across the member countries of the CACM to influence tariffs and taxes to its advantage. Documents demonstrate a high degree of access to governments and officials. The company conducted a coordinated, and largely successful, attempt to keep external tariff rates for cigarettes high and to reduce external tariffs for key inputs, whilst also influencing the harmonisation of excise taxes between countries. Protected by these high external tariffs, it reorganised its own operations to take advantage of regional economies of scale. In direct contradiction to arguments presented to CACM governments that affording the tobacco industry protection via high

  5. 40 CFR 761.217 - Exception reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.217 Exception reporting. (a)(1) A generator of PCB waste, who does not receive a copy of the manifest with the handwritten signature of the owner or operator of the designated facility within 35 days of the date the waste was accepted by the...

  6. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  7. 14 CFR 1203.409 - Exceptional cases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Exceptional cases. 1203.409 Section 1203.409 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM... authority is normally the Installation Security Classification Officer. Persons other than NASA...

  8. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  9. 40 CFR 1517.4 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY PUBLIC MEETING PROCEDURES OF THE COUNCIL ON ENVIRONMENTAL QUALITY § 1517.4 Exceptions. (a) A meeting or portion thereof may be closed to public observation...) Disclose investigative techniques and procedures, or, (vi) Endanger the life or physical safety of...

  10. How To Be an Exceptional Follower.

    ERIC Educational Resources Information Center

    Sevier, Robert A.

    1999-01-01

    Argues that college trustees and administrators must move beyond their image as docile and weak followers, and learn how to follow the leader they have chosen. Five follower types are identified, focusing on the characteristics and responsibilities of "exceptional" followers, who work closely with the leader and actively participate in decision…

  11. Architectural Considerations for Classrooms for Exceptional Children.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    Definitions are provided of the following exceptionalities: blind, partially sighted, physically handicapped, minimally brain injured, deaf, educable mentally retarded (primary, junior, and senior high levels), trainable mentally retarded, speech handicapped, and emotionally disturbed. Architectural guidelines specify classroom location, size,…

  12. 32 CFR 1907.21 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Exceptions. 1907.21 Section 1907.21 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY CHALLENGES TO... take no action on the challenge and will notify the challenger of this fact within 10 business days....

  13. 7 CFR 1956.99 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Exception authority. 1956.99 Section 1956.99 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) DEBT SETTLEMENT Debt Settlement-Farm Loan Programs and...

  14. 29 CFR 1905.28 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Exceptions. 1905.28 Section 1905.28 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR RULES OF PRACTICE FOR VARIANCES, LIMITATIONS, VARIATIONS, TOLERANCES, AND EXEMPTIONS UNDER THE...

  15. 27 CFR 555.182 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Exceptions. 555.182 Section 555.182 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES... or modified explosive materials; (2) Training in explosives detection or development or testing...

  16. 48 CFR 225.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Buy American Act-Supplies 225.103 Exceptions...)(A) Normally, use the evaluation procedures in Subpart 225.5, but consider recommending a public... offer will involve substantial domestic expenditures; (2) To ensure access to advanced...

  17. 8 CFR 258.2 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Transportation Act. (2) In order to invoke the hazardous cargo exception for safety and environmental protection... is in effect in the local port one or more collective bargaining agreements, each covering at least... longshore activity to be performed by the nonimmigrant crewman, or (ii) There is no collective...

  18. 8 CFR 258.2 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Transportation Act. (2) In order to invoke the hazardous cargo exception for safety and environmental protection... is in effect in the local port one or more collective bargaining agreements, each covering at least... longshore activity to be performed by the nonimmigrant crewman, or (ii) There is no collective...

  19. 8 CFR 258.2 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Transportation Act. (2) In order to invoke the hazardous cargo exception for safety and environmental protection... is in effect in the local port one or more collective bargaining agreements, each covering at least... longshore activity to be performed by the nonimmigrant crewman, or (ii) There is no collective...

  20. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  1. 40 CFR 761.217 - Exception reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 761.217 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.217 Exception reporting. (a)(1) A generator of PCB waste, who does not receive a copy of the manifest with the handwritten signature of the owner...

  2. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  3. 40 CFR 761.215 - Exception reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 761.215 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.215 Exception reporting. (a) A generator of PCB waste... the designated PCB commercial storage or disposal facility within 35 days of the date the waste...

  4. 7 CFR 4284.904 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Exception authority. 4284.904 Section 4284.904 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GRANTS Value-Added Producer Grant Program...

  5. 7 CFR 4284.904 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Exception authority. 4284.904 Section 4284.904 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GRANTS Value-Added Producer Grant Program...

  6. 7 CFR 4284.904 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Exception authority. 4284.904 Section 4284.904 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GRANTS Value-Added Producer Grant Program...

  7. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  8. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  9. 7 CFR 1944.75 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 13 2011-01-01 2009-01-01 true Exception authority. 1944.75 Section 1944.75 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  10. 7 CFR 1774.24 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Exception authority. 1774.24 Section 1774.24 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) SPECIAL EVALUATION ASSISTANCE FOR RURAL COMMUNITIES AND HOUSEHOLDS PROGRAM...

  11. 7 CFR 1924.122 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Exception authority. 1924.122 Section 1924.122 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  12. 7 CFR 1955.21 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1955.21 Section 1955.21 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  13. 7 CFR 1774.24 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Exception authority. 1774.24 Section 1774.24 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) SPECIAL EVALUATION ASSISTANCE FOR RURAL COMMUNITIES AND HOUSEHOLDS PROGRAM...

  14. 7 CFR 1956.148 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1956.148 Section 1956.148 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  15. 7 CFR 1774.24 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Exception authority. 1774.24 Section 1774.24 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) SPECIAL EVALUATION ASSISTANCE FOR RURAL COMMUNITIES AND HOUSEHOLDS PROGRAM...

  16. 7 CFR 1955.149 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1955.149 Section 1955.149 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  17. 7 CFR 1980.496 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 14 2011-01-01 2011-01-01 false Exception authority. 1980.496 Section 1980.496 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  18. 7 CFR 1980.397 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1980.397 Section 1980.397 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  19. 7 CFR 1924.122 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Exception authority. 1924.122 Section 1924.122 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  20. 7 CFR 1955.81 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 14 2012-01-01 2012-01-01 false Exception authority. 1955.81 Section 1955.81 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE...

  1. 49 CFR 107.606 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Exceptions. 107.606 Section 107.606 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS...

  2. 49 CFR 107.606 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Exceptions. 107.606 Section 107.606 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS...

  3. 49 CFR 107.606 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Exceptions. 107.606 Section 107.606 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS...

  4. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  5. Leiomyosarcoma of the Penis, an Exceptional Entity

    PubMed Central

    Romero Gonzalez, Edwin Javier; Marenco Jiménez, José L.; Mayorga Pineda, Maria P.; Martínez Morán, Alfonso; Castiñeiras Fernández, Jesús

    2015-01-01

    In tumors of the penis, mesenchymal tumors are extremely rare and within them, sarcomas are exceptional. We report a patient with a sarcomatous lesion treated with conservative surgery with good surgical outcome and the review of the literature, to present the latest advances in the treatment of this unusual entity. PMID:26793502

  6. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  7. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  8. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  9. 48 CFR 223.7304 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Hexavalent Chromium 223.7304 Exceptions. The prohibition in 223.7303 does not apply to— (a) Legacy systems and their related parts, subsystems, and components that already contain hexavalent chromium. However, alternatives to hexavalent chromium shall be considered by the appropriate official during system...

  10. 36 CFR 1194.3 - General exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... BOARD ELECTRONIC AND INFORMATION TECHNOLOGY ACCESSIBILITY STANDARDS General § 1194.3 General exceptions. (a) This part does not apply to any electronic and information technology operated by agencies, the... to electronic and information technology that is acquired by a contractor incidental to a...

  11. 36 CFR 1194.3 - General exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... BOARD ELECTRONIC AND INFORMATION TECHNOLOGY ACCESSIBILITY STANDARDS General § 1194.3 General exceptions. (a) This part does not apply to any electronic and information technology operated by agencies, the... to electronic and information technology that is acquired by a contractor incidental to a...

  12. 36 CFR 1194.3 - General exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... BOARD ELECTRONIC AND INFORMATION TECHNOLOGY ACCESSIBILITY STANDARDS General § 1194.3 General exceptions. (a) This part does not apply to any electronic and information technology operated by agencies, the... to electronic and information technology that is acquired by a contractor incidental to a...

  13. 48 CFR 1825.103 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... restrictions of the Buy American Act to Canadian end products with estimated values of $25,000 or less as... products on a parity with offers for domestic end products, except that applicable duty (whether or not a... products. (ii) The Assistant Administrator for Procurement has determined that for procurements subject...

  14. 48 CFR 225.103 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Organization Government Procurement Agreement, the Under Secretary of Defense (Acquisition, Technology, and... factors in 10 U.S.C. 2533— (1) At a level above the contracting officer for acquisitions valued at or... product. (ii) Except as provided in FAR 25.103(b)(3), the determination shall be approved— (A) At a...

  15. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  16. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  17. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  18. 30 CFR 75.402-2 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Exceptions. 75.402-2 Section 75.402-2 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Combustible Materials and Rock Dusting § 75.402-2...

  19. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  20. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  1. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  2. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  3. 40 CFR 60.593a - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... following exceptions to the provisions of subpart VVa of this part. (b)(1) Compressors in hydrogen service... is in hydrogen service. (2) Each compressor is presumed not to be in hydrogen service unless an owner or operator demonstrates that the piece of equipment is in hydrogen service. For a piece of...

  4. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... available high performance magnets that contain specialty metal, unless such high performance magnets are... specialty metals restrictions to magnets); and (D) COTS fasteners, unless— (1) The fasteners are... exception does not apply to high performance magnets containing specialty metals. See PGI...

  5. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... available high performance magnets that contain specialty metal, unless such high performance magnets are... specialty metals restrictions to magnets); and (D) COTS fasteners, unless— (1) The fasteners are... exception does not apply to high performance magnets containing specialty metals. See PGI...

  6. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... available high performance magnets that contain specialty metal, unless such high performance magnets are... specialty metals restrictions to magnets); and (D) COTS fasteners, unless— (1) The fasteners are... exception does not apply to high performance magnets containing specialty metals. See PGI...

  7. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... performance magnets that contain specialty metal, unless such high performance magnets are incorporated into... restrictions to magnets); and (D) COTS fasteners, unless— (1) The fasteners are incorporated into COTS end... exception does not apply to high performance magnets containing specialty metals. See PGI...

  8. 48 CFR 225.7003-3 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... available high performance magnets that contain specialty metal, unless such high performance magnets are... specialty metals restrictions to magnets); and (D) COTS fasteners, unless— (1) The fasteners are... exception does not apply to high performance magnets containing specialty metals. See PGI...

  9. Fort Lewis Exceptional Family Member Program (EFMP)

    ERIC Educational Resources Information Center

    Hebdon, Heather

    2007-01-01

    Located in the shadow of Mt. Rainier, Fort Lewis is the home of the highest per capita exceptional family member population in the Army. Ideally located on the Northwest coast of Washington State, Fort Lewis is home to the Strykers and First Brigade. Combined with its close proximity to McChord Air Force Base, the installation is ideally suited to…

  10. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  11. 12 CFR 229.13 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Exceptions. 229.13 Section 229.13 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Availability of Funds and Disclosure of...

  12. EXCEPTIONAL CHILDREN IN A MODERN SOCIETY.

    ERIC Educational Resources Information Center

    LOVE, HAROLD D.

    INTENDED FOR UNDERGRADUATES AND BEGINNING GRADUATE STUDENTS, THE TEXT INTRODUCES THE KINDS OF EXCEPTIONALITY, INCIDENCE FIGURES, AND IDENTIFICATION PROCEDURES. THE FOLLOWING TOPICS ARE ALSO CONSIDERED--(1) THE MENTALLY RETARDED, (2) THE GIFTED, (3) THE BLIND AND PARTIALLY SIGHTED, (4) SPEECH PROBLEMS, (5) THE DEAF AND HARD OF HEARING, (6)…

  13. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  14. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  15. 7 CFR 4288.107 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Exception authority. 4288.107 Section 4288.107 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE PAYMENT PROGRAMS Advanced Biofuel Payment...

  16. A Priceless Playground for Exceptional Children.

    ERIC Educational Resources Information Center

    Adkins, Patricia G.

    Described are 20 pieces of therapeutic playground equipment constructed by volunteers and fathers of children in the Early Learning Center for Exceptional Children (El Paso, Texas). It is noted that discarded and readily available materials (such as old tires) were used, and that no commercial playground equipment was purchased. Information on the…

  17. 26 CFR 1.358-4 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TAXES (Continued) Effects on Shareholders and Security Holders § 1.358-4 Exceptions. (a) Plan of... connection with such reorganization by the exchange of its stock or securities (or by the exchange of stock or securities of a corporation which is in control of the acquiring corporation) as the...

  18. 26 CFR 1.358-4 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... TAXES Effects on Shareholders and Security Holders § 1.358-4 Exceptions. (a) Plan of reorganization... with such reorganization by the exchange of its stock or securities (or by the exchange of stock or securities of a corporation which is in control of the acquiring corporation) as the consideration in...

  19. 26 CFR 1.358-4 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... TAXES (CONTINUED) Effects on Shareholders and Security Holders § 1.358-4 Exceptions. (a) Plan of... connection with such reorganization by the exchange of its stock or securities (or by the exchange of stock or securities of a corporation which is in control of the acquiring corporation) as the...

  20. 26 CFR 1.358-4 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... TAXES (CONTINUED) Effects on Shareholders and Security Holders § 1.358-4 Exceptions. (a) Plan of... connection with such reorganization by the exchange of its stock or securities (or by the exchange of stock or securities of a corporation which is in control of the acquiring corporation) as the...

  1. 26 CFR 1.358-4 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TAXES Effects on Shareholders and Security Holders § 1.358-4 Exceptions. (a) Plan of reorganization... with such reorganization by the exchange of its stock or securities (or by the exchange of stock or securities of a corporation which is in control of the acquiring corporation) as the consideration in...

  2. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  3. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  4. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  5. 14 CFR 93.133 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Exceptions. 93.133 Section 93.133 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports §...

  6. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  7. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  8. 48 CFR 23.104 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Exceptions. 23.104 Section 23.104 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND...

  9. 40 CFR 180.4 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Exceptions. 180.4 Section 180.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Definitions and Interpretative Regulations §...

  10. 49 CFR 391.2 - General exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... commercial motor vehicle is used to— (1) Transport farm machinery, supplies, or both, to or from a farm for custom-harvesting operations on a farm; or (2) Transport custom-harvested crops to storage or market. (b... AND LONGER COMBINATION VEHICLE (LCV) DRIVER INSTRUCTORS General § 391.2 General exceptions. (a)...

  11. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1 § 173.63 Packaging exceptions...-shore supply vessel; (3) Cargo compartment of a cargo vessel; or (4) Passenger-carrying aircraft used to...) criteria for reclassification as limited quantity material for transportation by highway, rail or...

  12. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... waste, marine pollutant, or is offered for transportation and transported byaircraft or vessel... SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1 § 173.63 Packaging exceptions...-shore supply vessel; (3) Cargo compartment of a cargo vessel; or (4) Passenger-carrying aircraft used...

  13. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1 § 173.63 Packaging exceptions...-shore supply vessel; (3) Cargo compartment of a cargo vessel; or (4) Passenger-carrying aircraft used to... hazardous substance, hazardous waste, marine pollutant, or is offered for transportation and transported...

  14. 49 CFR 173.63 - Packaging exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1 § 173.63 Packaging exceptions...-shore supply vessel; (3) Cargo compartment of a cargo vessel; or (4) Passenger-carrying aircraft used...

  15. Voices from the Classroom: Exceptional Teachers Speak.

    ERIC Educational Resources Information Center

    Maeroff, Gene I., Ed.

    The opinions and experiences reflected in this report are those of exceptional teachers chosen in a national competition, "Thanks to Teachers," sponsored by Apple Computer, Inc., the National Foundation for the Improvement of Education, the National Alliance of Business, and Group W Television. The report is divided into four sections: (1) the…

  16. 7 CFR 1775.68 - Exception authority.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 12 2012-01-01 2012-01-01 false Exception authority. 1775.68 Section 1775.68 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) TECHNICAL ASSISTANCE GRANTS Solid Waste Management Grants § 1775.68...

  17. 7 CFR 1775.68 - Exception authority.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 12 2011-01-01 2011-01-01 false Exception authority. 1775.68 Section 1775.68 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) TECHNICAL ASSISTANCE GRANTS Solid Waste Management Grants § 1775.68...

  18. 7 CFR 1775.68 - Exception authority.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Exception authority. 1775.68 Section 1775.68 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) TECHNICAL ASSISTANCE GRANTS Solid Waste Management Grants § 1775.68...

  19. 7 CFR 1775.68 - Exception authority.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 12 2014-01-01 2013-01-01 true Exception authority. 1775.68 Section 1775.68 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) TECHNICAL ASSISTANCE GRANTS Solid Waste Management Grants § 1775.68...

  20. 7 CFR 1775.68 - Exception authority.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 12 2013-01-01 2013-01-01 false Exception authority. 1775.68 Section 1775.68 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE (CONTINUED) TECHNICAL ASSISTANCE GRANTS Solid Waste Management Grants § 1775.68...

  1. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  2. 47 CFR 76.106 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Exceptions. 76.106 Section 76.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Network Non-duplication Protection, Syndicated Exclusivity and Sports...

  3. 48 CFR 225.7603 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Exceptions. 225.7603 Section 225.7603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Secondary Arab Boycott of Israel...

  4. 48 CFR 225.7603 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Exceptions. 225.7603 Section 225.7603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Secondary Arab Boycott of Israel...

  5. 48 CFR 225.7603 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Exceptions. 225.7603 Section 225.7603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Secondary Arab Boycott of Israel...

  6. 48 CFR 225.7603 - Exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Exceptions. 225.7603 Section 225.7603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Secondary Arab Boycott of Israel...

  7. 48 CFR 225.7603 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Exceptions. 225.7603 Section 225.7603 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Secondary Arab Boycott of Israel...

  8. Counseling with Mothers of Exceptional Children

    ERIC Educational Resources Information Center

    Kaplan, Bert L.

    1971-01-01

    It is possible for elementary school guidance counselors to help mothers of exceptional children face the severe reality demands they experience as internal turmoil marked by anger guilt and self depreciation. Once their feelings have been elicited and legitimized exploration of how feelings influence behavior toward children becomes possible.…

  9. 42 CFR 423.578 - Exceptions process.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Grievances, Coverage... to a plan's tiered cost-sharing structure. Each Part D plan sponsor that provides prescription drug... category as the requested prescription drug that is the subject of the exceptions request. (3) An...

  10. 42 CFR 423.578 - Exceptions process.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) MEDICARE PROGRAM (CONTINUED) VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Grievances, Coverage... to a plan's tiered cost-sharing structure. Each Part D plan sponsor that provides prescription drug... category as the requested prescription drug that is the subject of the exceptions request. (3) An...

  11. 40 CFR 262.42 - Exception reporting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Recordkeeping and Reporting § 262.42 Exception reporting. (a)(1) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month, or... hazardous waste. (2) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month,...

  12. 40 CFR 262.42 - Exception reporting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Recordkeeping and Reporting § 262.42 Exception reporting. (a)(1) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month, or... hazardous waste. (2) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month,...

  13. 40 CFR 262.42 - Exception reporting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Recordkeeping and Reporting § 262.42 Exception reporting. (a)(1) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month, or... hazardous waste. (2) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month,...

  14. 40 CFR 262.42 - Exception reporting.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Recordkeeping and Reporting § 262.42 Exception reporting. (a)(1) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month, or... hazardous waste. (2) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month,...

  15. 40 CFR 262.42 - Exception reporting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Recordkeeping and Reporting § 262.42 Exception reporting. (a)(1) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month, or... hazardous waste. (2) A generator of 1,000 kilograms or greater of hazardous waste in a calendar month,...

  16. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... solicited. This exception does not apply to proposed contract actions covered by the World Trade Organization Government Procurement Agreement or a Free Trade Agreement (see Subpart 25.4); (13) The proposed... organizations, has the effect of requiring that the acquisition shall be from specified sources; (4)...

  17. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... solicited. This exception does not apply to proposed contract actions covered by the World Trade Organization Government Procurement Agreement or a Free Trade Agreement (see Subpart 25.4); (13) The proposed... organizations, has the effect of requiring that the acquisition shall be from specified sources; (4)...

  18. 48 CFR 5.202 - Exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... solicited. This exception does not apply to proposed contract actions covered by the World Trade Organization Government Procurement Agreement or a Free Trade Agreement (see Subpart 25.4); (13) The proposed... organizations, has the effect of requiring that the acquisition shall be from specified sources; (4)...

  19. 12 CFR 344.2 - Exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Exceptions. 344.2 Section 344.2 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY RECORDKEEPING... accurately reflect the information required under this part and provide an adequate basis for an audit....

  20. An "Exceptional" NBPTS Certificate for Special Educators.

    ERIC Educational Resources Information Center

    Helms, Ronald G.

    2000-01-01

    This article describes the new National Board for Professional Teaching Standards (NBPTS) certificate for teachers of students with disabilities. The certification process, the required Exceptional Needs portfolio, the assessment center, and the application fee are discussed, along with answers to frequently asked questions about the NBPTS.…

  1. 77 FR 20614 - Petition Requesting Exception from Lead Content Limits; Notice Granting Exception

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... the issues raised by the petition. In the Federal Register of November 16, 2011 (76 FR 70975), we..., 2012 (77 FR 478), we reopened the comment period for 30 days, with comments due on February 6, 2012. We... COMMISSION Petition Requesting Exception from Lead Content Limits; Notice Granting Exception AGENCY:...

  2. Breeding Common Bean for resistance to Common Blight: A review

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Common blight {caused by Xanthomonas campestris pv. phaseoli Smith (Dye) is a major bacterial disease causing >40% seed yield and quality losses in common bean (Phaseolus vulgaris L.) worldwide. Use of resistant cultivars is crucial for its effective, economical, and environment friendly integarated...

  3. Space Science IS Accessible to Students with Exceptional Needs: Results from Exceptional Needs Workshops

    NASA Astrophysics Data System (ADS)

    Runyon, C. J.; Merritt, M.; Guimond, K.

    2003-12-01

    The majority of students with disabilities in the US are required to achieve the same academic levels as their non-impaired peers. Unfortunately, there are few specialized materials to help these exceptional students. To assist students in meeting their goals, SERCH, a NASA Office of Space Science Broker/Facilitator, has been working with NASA education product developers and educators from informal and formal settings to identify what kinds of materials they need and what mediums will work best. As a result of both direct classrooms observations and hands-on workshops we have begun generating adaptive lessons plans that meet the national standards for Science, Technology, Engineering and Mathematics. During the workshops, participants simulate various disabilities (e.g., hearing, vision, orthopedic impairments, learning difficulties) while working through Space Science activities and discuss necessary adaptations/modifications in real-time. For example, we modified the Solar System Distance activity first designed by ASU to include the use of larger beads or pom-poms instead of the suggested small plastic beads. This simple adaptation permits students with orthopedic impairments to more readily take part in the lesson and to actively "observe" the distance between the planets. Examples of this activity and more will be illustrated. In addition to making modifications and suggestions for adaptations, workshop participants shared many simple recommendations that can help ALL learners participate more readily in classroom activities and discussions. Among these are: (1) Use simple, sans-serif fonts and high contrast presentation media (e.g., white text on black is most effective); (2) Repetition and use of multiple presentation modes is very helpful. (3) Actively involve the learner, and (4) Keep things simple to begin with, then work toward the more complex - think of the audience, the ultimate user.

  4. Asymptotic dynamics of the exceptional Bianchi cosmologies

    NASA Astrophysics Data System (ADS)

    Hewitt, C. G.; Horwood, J. T.; Wainwright, J.

    2003-05-01

    In this paper we give, for the first time, a qualitative description of the asymptotic dynamics of a class of non-tilted spatially homogeneous (SH) cosmologies, the so-called exceptional Bianchi cosmologies, which are of Bianchi type VI$_{-1/9}$. This class is of interest for two reasons. Firstly, it is generic within the class of non-tilted SH cosmologies, being of the same generality as the models of Bianchi types VIII and IX. Secondly, it is the SH limit of a generic class of spatially inhomogeneous $G_{2}$ cosmologies. Using the orthonormal frame formalism and Hubble-normalized variables, we show that the exceptional Bianchi cosmologies differ from the non-exceptional Bianchi cosmologies of type VI$_{h}$ in two significant ways. Firstly, the models exhibit an oscillatory approach to the initial singularity and hence are not asymptotically self-similar. Secondly, at late times, although the models are asymptotically self-similar, the future attractor for the vacuum-dominated models is the so-called Robinson-Trautman SH model instead of the vacuum SH plane wave models.

  5. Giant nonreciprocity near exceptional-point degeneracies

    NASA Astrophysics Data System (ADS)

    Thomas, Roney; Li, Huanan; Ellis, F. M.; Kottos, Tsampikos

    2016-10-01

    We show that gyrotropic structures with balanced gain and loss that respect antilinear symmetries exhibit a giant nonreciprocity at the so-called exact phase where the eigenfrequencies of the isolated non-Hermitian setup are real. The effect occurs in a parameter domain near an exceptional- point (EP) degeneracy, where mode orthogonality collapses. The theoretical predictions are confirmed numerically in the microwave domain, where a nonreciprocal transport above 90 dB is demonstrated, and are further verified using lumped-circuitry modeling. The analysis allows us to speculate the universal nature of the phenomenon for any wave system where EP and gyrotropy can coexist.

  6. Generalized IIB supergravity from exceptional field theory

    NASA Astrophysics Data System (ADS)

    Baguet, Arnaud; Magro, Marc; Samtleben, Henning

    2017-03-01

    The background underlying the η-deformed AdS 5 × S 5 sigma-model is known to satisfy a generalization of the IIB supergravity equations. Their solutions are related by T-duality to solutions of type IIA supergravity with non-isometric linear dilaton. We show how the generalized IIB supergravity equations can be naturally obtained from exceptional field theory. Within this manifestly duality covariant formulation of maximal supergravity, the generalized IIB supergravity equations emerge upon imposing on the fields a simple Scherk-Schwarz ansatz which respects the section constraint.

  7. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect...

  8. Exceptional quantum geometry and particle physics

    NASA Astrophysics Data System (ADS)

    Dubois-Violette, Michel

    2016-11-01

    Based on an interpretation of the quark-lepton symmetry in terms of the unimodularity of the color group SU (3) and on the existence of 3 generations, we develop an argumentation suggesting that the "finite quantum space" corresponding to the exceptional real Jordan algebra of dimension 27 (the Euclidean Albert algebra) is relevant for the description of internal spaces in the theory of particles. In particular, the triality which corresponds to the 3 off-diagonal octonionic elements of the exceptional algebra is associated to the 3 generations of the Standard Model while the representation of the octonions as a complex 4-dimensional space C ⊕C3 is associated to the quark-lepton symmetry (one complex for the lepton and 3 for the corresponding quark). More generally it is suggested that the replacement of the algebra of real functions on spacetime by the algebra of functions on spacetime with values in a finite-dimensional Euclidean Jordan algebra which plays the role of "the algebra of real functions" on the corresponding almost classical quantum spacetime is relevant in particle physics. This leads us to study the theory of Jordan modules and to develop the differential calculus over Jordan algebras (i.e. to introduce the appropriate notion of differential forms). We formulate the corresponding definition of connections on Jordan modules.

  9. Lumbosacral plexus in Brazilian Common Opossum.

    PubMed

    Senos, R; Ribeiro, M S; Benedicto, H G; Kfoury Júnior, J R

    2016-01-01

    The opossum has been suggested as an animal model for biomedical studies due to its adaptability to captivity and number of births per year. Despite many studies on morphology and experimental neurology using this opossum model, the literature does not offer details of the nerves of the lumbosacral plexus in this species. Ten lumbosacral plexus were dissected to describe the peripheral innervations of the Brazilian Common Opossum (Didelphis aurita) and compare the results with Eutheria clade species. The tensor fasciae latae muscle was absent and there was only one sartorius muscle for each limb. The distribution of the nerves were similar to other mammals, except for the caudal gluteal nerve, sartorius muscle innervations and the position of the pudendal nerve which arose from the major ischiatic foramen together with the ischiatic nerve, the cranial gluteal nerve and the caudal gluteal nerve. No anatomical variation was found. The special position of the pudendal nerve suggested that the Brazilian Common Opossum is a better model than rats or rabbits in surgical procedures with that specific nerve. In addition, the study revealed that the pelvic limb nerves are not an invariable structure of reference for muscle homology and homonym as reported previously. New investigation using other species of opossums are necessary to best comprehend the lumbosacral plexus distribution in the Methatheria clade and to confirm that other opossum species is eligible as a good model for pudendal nerve studies.

  10. Exceptionally elevated triglyceride in severe lipemia retinalis

    PubMed Central

    Yin, Han Y; Warman, Roberto; Suh, Edward H; Cheng, Anny MS

    2016-01-01

    Purpose To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG). Design Observational case report. Observations A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation. Results Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months. Conclusion Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. PMID:27799830

  11. Exceptionally preserved jellyfishes from the Middle Cambrian.

    PubMed

    Cartwright, Paulyn; Halgedahl, Susan L; Hendricks, Jonathan R; Jarrard, Richard D; Marques, Antonio C; Collins, Allen G; Lieberman, Bruce S

    2007-10-31

    Cnidarians represent an early diverging animal group and thus insight into their origin and diversification is key to understanding metazoan evolution. Further, cnidarian jellyfish comprise an important component of modern marine planktonic ecosystems. Here we report on exceptionally preserved cnidarian jellyfish fossils from the Middle Cambrian (approximately 505 million years old) Marjum Formation of Utah. These are the first described Cambrian jellyfish fossils to display exquisite preservation of soft part anatomy including detailed features of structures interpreted as trailing tentacles and subumbrellar and exumbrellar surfaces. If the interpretation of these preserved characters is correct, their presence is diagnostic of modern jellyfish taxa. These new discoveries may provide insight into the scope of cnidarian diversity shortly after the Cambrian radiation, and would reinforce the notion that important taxonomic components of the modern planktonic realm were in place by the Cambrian period.

  12. Projective Hilbert space structures at exceptional points

    NASA Astrophysics Data System (ADS)

    Günther, Uwe; Rotter, Ingrid; Samsonov, Boris F.

    2007-07-01

    A non-Hermitian complex symmetric 2 × 2-matrix toy model is used to study projective Hilbert space structures in the vicinity of exceptional points (EPs). The bi-orthogonal eigenvectors of a diagonalizable matrix are Puiseux-expanded in terms of the root vectors at the EP. It is shown that the apparent contradiction between the two incompatible normalization conditions with finite and singular behaviour in the EP-limit can be resolved by projectively extending the original Hilbert space. The complementary normalization conditions correspond then to two different affine charts of this enlarged projective Hilbert space. Geometric phase and phase-jump behaviour are analysed, and the usefulness of the phase rigidity as measure for the distance to EP configurations is demonstrated. Finally, EP-related aspects of {\\cal P}{\\cal T} -symmetrically extended quantum mechanics are discussed and a conjecture concerning the quantum brachistochrone problem is formulated.

  13. Bronchial haemangioma: exceptionally rare cause of haemoptysis.

    PubMed

    Jennings, Scott; Tharion, John; Jones, Peter; Brown, Michael

    2013-12-01

    Bronchial haemangioma is an exceptionally rare cause of haemoptysis in the adult. There are currently less than 10 recorded cases in the literature. Airway haemangiomas are generally seen in infants with coexistent cutaneous haemangiomas. The incidence of bronchial haemangioma in adults remains unknown. This case reports the diagnosis and treatment of a bronchial haemangioma in a 56 year-old male presenting with a one-month history of haemoptysis. Bronchial haemangioma diagnosis was confirmed and excision performed by bronchoscopy without complication. Bronchial haemangioma should be a considered differential diagnosis in the presence of meaningful haemoptysis when an endoluminal lesion is visualised on computed tomography scan. This case also demonstrates that bronchial haemangiomas can be successfully removed via bronchoscopy with minimal risk and discomfort to the patient.

  14. Common Variable Immunodeficiency.

    PubMed

    Saikia, Biman; Gupta, Sudhir

    2016-04-01

    Common variable immunodeficiency (CVID) is the most common primary immunodeficiency of young adolescents and adults which also affects the children. The disease remains largely under-diagnosed in India and Southeast Asian countries. Although in majority of cases it is sporadic, disease may be inherited in a autosomal recessive pattern and rarely, in autosomal dominant pattern. Patients, in addition to frequent sino-pulmonary infections, are also susceptible to various autoimmune diseases and malignancy, predominantly lymphoma and leukemia. Other characteristic lesions include lymphocytic and granulomatous interstitial lung disease, and nodular lymphoid hyperplasia of gut. Diagnosis requires reduced levels of at least two immunoglobulin isotypes: IgG with IgA and/or IgM and impaired specific antibody response to vaccines. A number of gene mutations have been described in CVID; however, these genetic alterations account for less than 20% of cases of CVID. Flow cytometry aptly demonstrates a disturbed B cell homeostasis with reduced or absent memory B cells and increased CD21(low) B cells and transitional B cell populations. Approximately one-third of patients with CVID also display T cell functional defects. Immunoglobulin therapy remains the mainstay of treatment. Immunologists and other clinicians in India and other South East Asian countries need to be aware of CVID so that early diagnosis can be made, as currently, majority of these patients still go undiagnosed.

  15. "i" Before "e" Except after----what??

    ERIC Educational Resources Information Center

    Donlan, Dan

    1986-01-01

    Discusses the enigma of what and how people know apparently trivial information. Presents an experiment, expected answers, and actual responses to grammar questions to determine the degree of common knowledge in professional trivia. Concludes that further research may bring a clearer understanding of the "tradition" of language teaching…

  16. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... exception to the risk management purchase requirement in § 760.104, the participant must elect such... subpart apply in the event a participant does not obtain an exception according to this section....

  17. The School Psychologist and the Exceptional Child.

    ERIC Educational Resources Information Center

    Scholl, Geraldine T., Ed.

    Intended for use with students preparing for careers in school psychology, the text assumes little familiarity with special education and focuses on those aspects of special education of greatest relevance for the assessment process. The book is divided into two major parts: Part I, "General Considerations," includes a brief description of the…

  18. Exceptional overproduction of a functional human membrane protein.

    PubMed

    Nyblom, Maria; Oberg, Fredrik; Lindkvist-Petersson, Karin; Hallgren, Karin; Findlay, Heather; Wikström, Jennie; Karlsson, Anders; Hansson, Orjan; Booth, Paula J; Bill, Roslyn M; Neutze, Richard; Hedfalk, Kristina

    2007-11-01

    Eukaryotic--especially human--membrane protein overproduction remains a major challenge in biochemistry. Heterologously overproduced and purified proteins provide a starting point for further biochemical, biophysical and structural studies, and the lack of sufficient quantities of functional membrane proteins is frequently a bottleneck hindering this. Here, we report exceptionally high production levels of a correctly folded and crystallisable recombinant human integral membrane protein in its active form; human aquaporin 1 (hAQP1) has been heterologously produced in the membranes of the methylotrophic yeast Pichia pastoris. After solubilisation and a two step purification procedure, at least 90 mg hAQP1 per liter of culture is obtained. Water channel activity of this purified hAQP1 was verified by reconstitution into proteoliposomes and performing stopped-flow vesicle shrinkage measurements. Mass spectrometry confirmed the identity of hAQP1 in crude membrane preparations, and also from purified protein reconstituted into proteoliposomes. Furthermore, crystallisation screens yielded diffraction quality crystals of untagged recombinant hAQP1. This study illustrates the power of the yeast P. pastoris as a host to produce exceptionally high yields of a functionally active, human integral membrane protein for subsequent functional and structural characterization.

  19. American Indian Exceptional Children and Youth. An ERIC Exceptional Child Education Report.

    ERIC Educational Resources Information Center

    Johnson, Marilyn J., Ed.; Ramirez, Bruce A., Ed.

    The document contains summaries of papers and ensuing discussions presented at a 1985 symposium on exceptional American Indian children and youth. The opening address (by Beverly Valley, a parent and school board member) stresses the role of parents and the need for less culturally biased testing. Two papers deal with parent and family…

  20. Connecting for High Potential..."The Exceptionality of Being Twice-Exceptional."

    ERIC Educational Resources Information Center

    Danielian, Jeff; Nilles, Kathleen

    2015-01-01

    What's not often well-known or well-understood is that students who are gifted may also have a special need or disability--just as students with disabilities may also be gifted. The term "twice-exceptional," also referred to as "2e," is used to describe gifted children who, according to the Joint Commission on Twice-Exceptional…

  1. Exceptional Convergent Evolution in a Virus

    PubMed Central

    Bull, J. J.; Badgett, M. R.; Wichman, H. A.; Huelsenbeck, J. P.; Hillis, D. M.; Gulati, A.; Ho, C.; Molineux, I. J.

    1997-01-01

    Replicate lineages of the bacteriophage φX 174 adapted to growth at high temperature on either of two hosts exhibited high rates of identical, independent substitutions. Typically, a dozen or more substitutions accumulated in the 5.4-kilobase genome during propagation. Across the entire data set of nine lineages, 119 independent substitutions occurred at 68 nucleotide sites. Over half of these substitutions, accounting for one third of the sites, were identical with substitutions in other lineages. Some convergent substitutions were specific to the host used for phage propagation, but others occurred across both hosts. Continued adaptation of an evolved phage at high temperature, but on the other host, led to additional changes that included reversions of previous substitutions. Phylogenetic reconstruction using the complete genome sequence not only failed to recover the correct evolutionary history because of these convergent changes, but the true history was rejected as being a significantly inferior fit to the data. Replicate lineages subjected to similar environmental challenges showed similar rates of substitution and similar rates of fitness improvement across corresponding times of adaptation. Substitution rates and fitness improvements were higher during the initial period of adaptation than during a later period, except when the host was changed. PMID:9409816

  2. Stem cell policy exceptionalism: proceed with caution.

    PubMed

    Lomax, Geoffrey P; Peckman, Steven R

    2012-06-01

    The term "stem cell exceptionalism" has been used to characterize the policy response to controversies surrounding human embryonic stem cell research. For example, governments and funding agencies have adopted policies governing the derivation and use of human embryonic stem cell lines. These policies have effectively served to fill gaps in existing guidelines and regulations and signal that scientists are committed to a responsible framework for the conduct of research involving human embryos. Recent publications discuss whether ethical and policy issues associated with induced pluripotent cells (iPSCs) from non-embryonic sources create a need for further policy intervention. We suggest many of the issues identified by commentators may be addressed through the application of established policy frameworks governing the use of tissue, human stem cells, and research participation by human research subjects. To the extent, iPSC research intersects with hESC research (e.g. the creation of human gametes and/or embryos), the policy framework governing hESC appears sufficiently robust at this time.

  3. Exceptional groups, symmetric spaces and applications

    SciTech Connect

    Cerchiai, Bianca L.; Cacciatori, Sergio L.

    2009-03-31

    In this article we provide a detailed description of a technique to obtain a simple parameterization for different exceptional Lie groups, such as G{sub 2}, F{sub 4} and E{sub 6}, based on their fibration structure. For the compact case, we construct a realization which is a generalization of the Euler angles for SU(2), while for the non compact version of G{sub 2(2)}/SO(4) we compute the Iwasawa decomposition. This allows us to obtain not only an explicit expression for the Haar measure on the group manifold, but also for the cosets G{sub 2}/SO(4), G{sub 2}/SU(3), F{sub 4}/Spin(9), E{sub 6}/F{sub 4} and G{sub 2(2)}/SO(4) that we used to find the concrete realization of the general element of the group. Moreover, as a by-product, in the simplest case of G{sub 2}/SO(4), we have been able to compute an Einstein metric and the vielbein. The relevance of these results in physics is discussed.

  4. An exceptional 5:4 enantiomeric structure.

    PubMed

    Wachter, Erin; Glazer, Edith C; Parkin, Sean; Brock, Carolyn Pratt

    2016-04-01

    The only crystals that could be grown from racemic solutions of the PF6(-) salt of the resolvable cation [Ru(2,9-dimethyl-1,10-phenanthroline)2(dipyrido[3,2-d:2',3'-f]quinoxaline)](2+) have translational symmetry only (space group P1), contain nine independent sets of ions, and include numerous independent solvent molecules (11 acetone, one diethyl ether and possibly several water molecules). Layers of hydrophobic cations alternate with layers containing most of the anions and solvent molecules. All nine cations have the same basic conformation, which is distorted by the presence of the methyl substituents on the two 1,10-phenanthroline ligands. Four pairs of enantiomeric cations within a layer are related by approximate inversion centers; the ninth cation, which shows no sign of disorder, makes the layer chiral. Within the cation layers stripes parallel to [110] of six cations alternate with stripes of three; the local symmetry and the cation orientations are different in the two stripes. These stripes are reflected in the organization of the anion/solvent layer. The ca 80:20 inversion twinning found indicates that enantiomeric preference is transmitted less perfectly across the anion/solvent layer than within the cation layer. The structure is exceptional in having nine independent formula units and an unbalanced set (ratio 4:5) of resolvable enantiomers. The difficulty in growing crystals of this material is consistent with its structural complexity.

  5. Major Joint/Combined Operations

    DTIC Science & Technology

    2008-01-01

    engagements, strikes) conducted by various combat forces of a single or several services, coordinated in time and place to accomplish an...operational and sometimes strategic objective in an operational area. These actions are conducted simultaneously or sequentially in accordance with a common...In generic terms, a major operation can be described as consisting of a series of related major and minor tactical actions by two or more combat

  6. Une Exception Francaise: Les Grandes Ecoles (A French Exception: The Great Schools).

    ERIC Educational Resources Information Center

    Kimmel, Alain

    1996-01-01

    Examines the role of exceptional schools in France that have produced famous personages such as Charles de Gaulle and Jean-Paul Sartre. The schools reviewed include L'Ecole Nationale d'Administration, L'Ecole Polytechnique, L'Ecole Normale Superieure, L'Ecole des Hautes Etudes Commerciales, Saint-Cyr, and L'Institut d'Etudes Politiques de Paris.…

  7. NIH exceptional responders to cancer therapy study launched

    Cancer.gov

    The Exceptional Responders Initiative, a study to investigate the molecular factors of tumors associated with exceptional treatment responses of cancer patients to drug therapies, was launched today by NCI. Scientists will attempt to identify the molecula

  8. 46 CFR 80.20 - Exception to requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... STANDARDS AND COUNTRY OF REGISTRY § 80.20 Exception to requirements. (a) This part does not apply to vessels... Sea, 1974. (b) If the exception in paragraph (a) of this section applies, the country of registry...

  9. 46 CFR 80.20 - Exception to requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... STANDARDS AND COUNTRY OF REGISTRY § 80.20 Exception to requirements. (a) This part does not apply to vessels... Sea, 1974. (b) If the exception in paragraph (a) of this section applies, the country of registry...

  10. 46 CFR 80.20 - Exception to requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... STANDARDS AND COUNTRY OF REGISTRY § 80.20 Exception to requirements. (a) This part does not apply to vessels... Sea, 1974. (b) If the exception in paragraph (a) of this section applies, the country of registry...

  11. 46 CFR 80.20 - Exception to requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... STANDARDS AND COUNTRY OF REGISTRY § 80.20 Exception to requirements. (a) This part does not apply to vessels... Sea, 1974. (b) If the exception in paragraph (a) of this section applies, the country of registry...

  12. Best Communication Practices for Preparation of Exceptional Event Demonstrations

    EPA Pesticide Factsheets

    OAQPS developed this document of Best Practices based on input received from EPA regional offices and selected state/local air agencies who submitted Exceptional Event Demonstrations under the 2007 version of the Exceptional Events Rule (EE Rule).

  13. 20 CFR 437.6 - Additions and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... classes of grants and grantees subject to this part, SSA may not impose additional administrative requirements except in codified regulations published in the Federal Register. (b) Exceptions for classes...

  14. 20 CFR 437.6 - Additions and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... classes of grants and grantees subject to this part, SSA may not impose additional administrative requirements except in codified regulations published in the Federal Register. (b) Exceptions for classes...

  15. 20 CFR 437.6 - Additions and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... classes of grants and grantees subject to this part, SSA may not impose additional administrative requirements except in codified regulations published in the Federal Register. (b) Exceptions for classes...

  16. 20 CFR 437.6 - Additions and exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... classes of grants and grantees subject to this part, SSA may not impose additional administrative requirements except in codified regulations published in the Federal Register. (b) Exceptions for classes...

  17. 20 CFR 437.6 - Additions and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND... classes of grants and grantees subject to this part, SSA may not impose additional administrative requirements except in codified regulations published in the Federal Register. (b) Exceptions for classes...

  18. Implant fractures: Rare but not exceptional

    PubMed Central

    Sanivarapu, Sahitya; Moogla, Srinivas; Kuntcham, Rupa Sruthi; Kolaparthy, Lakshmi Kanth

    2016-01-01

    Fabrication of dentures aided with implants has become a preferred treatment option for rehabilitation of completely and partially edentulous patients when durability is concerned. Simulation to natural teeth in terms of esthetics and to a greater extent in function can be considered as key elements in the raise of implant dentistry worldwide. Despite its high success rate, therapy with osseointegrated dental implants is not free of complications. Implant failure can occur for other reasons, with implant fracture being one of the major reasons for late failure. Although the incidence of implant fractures may be low, it invariably effects the patient and also clinician. Thus, sound evidence based knowledge of cause of fracture is mandatory for that careful treatment that can reduce the incidence of fracture helping in a better treatment plan. The aim of this review is to enlighten the various causes of implant fracture. PMID:27041830

  19. 14 CFR Appendix B to Part 43 - Recording of Major Repairs and Major Alterations

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Alterations B Appendix B to Part 43 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT MAINTENANCE, PREVENTIVE MAINTENANCE, REBUILDING, AND ALTERATION Pt. 43, App. B Appendix B to Part 43—Recording of Major Repairs and Major Alterations (a) Except as provided in paragraphs...

  20. 45 CFR 670.9 - Antarctic Conservation Act enforcement exception.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Antarctic Conservation Act enforcement exception... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.9 Antarctic Conservation Act enforcement exception. Paragraphs (a) through (d) of § 670.4 shall not apply to acts...

  1. 45 CFR 670.9 - Antarctic Conservation Act enforcement exception.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Antarctic Conservation Act enforcement exception... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.9 Antarctic Conservation Act enforcement exception. Paragraphs (a) through (d) of § 670.4 shall not apply to acts...

  2. 45 CFR 670.9 - Antarctic Conservation Act enforcement exception.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Antarctic Conservation Act enforcement exception... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.9 Antarctic Conservation Act enforcement exception. Paragraphs (a) through (d) of § 670.4 shall not apply to acts...

  3. 45 CFR 670.9 - Antarctic Conservation Act enforcement exception.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Antarctic Conservation Act enforcement exception... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.9 Antarctic Conservation Act enforcement exception. Paragraphs (a) through (d) of § 670.4 shall not apply to acts...

  4. 45 CFR 670.9 - Antarctic Conservation Act enforcement exception.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Antarctic Conservation Act enforcement exception... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.9 Antarctic Conservation Act enforcement exception. Paragraphs (a) through (d) of § 670.4 shall not apply to acts...

  5. Challenging Exceptionally Bright Children in Early Childhood Classrooms

    ERIC Educational Resources Information Center

    Gadzikowski, Ann

    2013-01-01

    Nearly every group of children includes at least one exceptionally bright child. From the especially creative child to the child who has already mastered learning outcomes to the "twice exceptional" child, exceptionally bright children have a wide range of talents and behaviors. This book will help you understand what it means to be…

  6. 21 CFR 1316.61 - Exceptions to rulings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exceptions to rulings. 1316.61 Section 1316.61 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Hearings § 1316.61 Exceptions to rulings. Exceptions to rulings...

  7. 5 CFR 6.6 - Revocation of exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Revocation of exceptions. 6.6 Section 6.6 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES EXCEPTIONS FROM THE COMPETITIVE SERVICE (RULE VI) § 6.6 Revocation of exceptions. OPM may remove any position from or may revoke in...

  8. 28 CFR 551.5 - Restrictions and exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Restrictions and exceptions. 551.5 Section 551.5 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT MISCELLANEOUS Grooming § 551.5 Restrictions and exceptions. The Warden may impose restrictions or exceptions...

  9. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances...

  10. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances...

  11. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 2 2013-07-01 2013-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances...

  12. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 2 2014-07-01 2014-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances...

  13. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances...

  14. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false De minimis exception. 760.613 Section 760.613....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... coverage for a crop exceeds 10 percent of the value of that coverage. (b) To be eligible for a de...

  15. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false De minimis exception. 760.613 Section 760.613....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... coverage for a crop exceeds 10 percent of the value of that coverage. (b) To be eligible for a de...

  16. 7 CFR 760.613 - De minimis exception.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false De minimis exception. 760.613 Section 760.613....613 De minimis exception. (a) Participants seeking the de minimis exception to the risk management... coverage for a crop exceeds 10 percent of the value of that coverage. (b) To be eligible for a de...

  17. 33 CFR 158.320 - Reception facilities: Capacity, and exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Reception facilities: Capacity, and exceptions. 158.320 Section 158.320 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Residue § 158.320 Reception facilities: Capacity, and exceptions. (a) Except as allowed in paragraph...

  18. 33 CFR 158.320 - Reception facilities: Capacity, and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Reception facilities: Capacity, and exceptions. 158.320 Section 158.320 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Residue § 158.320 Reception facilities: Capacity, and exceptions. (a) Except as allowed in paragraph...

  19. 33 CFR 158.320 - Reception facilities: Capacity, and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Reception facilities: Capacity, and exceptions. 158.320 Section 158.320 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Residue § 158.320 Reception facilities: Capacity, and exceptions. (a) Except as allowed in paragraph...

  20. 33 CFR 158.320 - Reception facilities: Capacity, and exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Reception facilities: Capacity, and exceptions. 158.320 Section 158.320 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Residue § 158.320 Reception facilities: Capacity, and exceptions. (a) Except as allowed in paragraph...

  1. 33 CFR 158.320 - Reception facilities: Capacity, and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Reception facilities: Capacity, and exceptions. 158.320 Section 158.320 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Residue § 158.320 Reception facilities: Capacity, and exceptions. (a) Except as allowed in paragraph...

  2. 5 CFR 1.4 - Extent of the excepted service.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Extent of the excepted service. 1.4 Section 1.4 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES COVERAGE AND DEFINITIONS (RULE I) § 1.4 Extent of the excepted service. (a) The excepted service shall include all...

  3. S-layer and cytoplasmic membrane - exceptions from the typical archaeal cell wall with a focus on double membranes.

    PubMed

    Klingl, Andreas

    2014-01-01

    The common idea of typical cell wall architecture in archaea consists of a pseudo-crystalline proteinaceous surface layer (S-layer), situated upon the cytoplasmic membrane. This is true for the majority of described archaea, hitherto. Within the crenarchaea, the S-layer often represents the only cell wall component, but there are various exceptions from this wall architecture. Beside (glycosylated) S-layers in (hyper)thermophilic cren- and euryarchaea as well as halophilic archaea, one can find a great variety of other cell wall structures like proteoglycan-like S-layers (Halobacteria), glutaminylglycan (Natronococci), methanochondroitin (Methanosarcina) or double layered cell walls with pseudomurein (Methanothermus and Methanopyrus). The presence of an outermost cellular membrane in the crenarchaeal species Ignicoccus hospitalis already gave indications for an outer membrane similar to Gram-negative bacteria. Although there is just limited data concerning their biochemistry and ultrastructure, recent studies on the euryarchaeal methanogen Methanomassiliicoccus luminyensis, cells of the ARMAN group, and the SM1 euryarchaeon delivered further examples for this exceptional cell envelope type consisting of two membranes.

  4. S-layer and cytoplasmic membrane – exceptions from the typical archaeal cell wall with a focus on double membranes

    PubMed Central

    Klingl, Andreas

    2014-01-01

    The common idea of typical cell wall architecture in archaea consists of a pseudo-crystalline proteinaceous surface layer (S-layer), situated upon the cytoplasmic membrane. This is true for the majority of described archaea, hitherto. Within the crenarchaea, the S-layer often represents the only cell wall component, but there are various exceptions from this wall architecture. Beside (glycosylated) S-layers in (hyper)thermophilic cren- and euryarchaea as well as halophilic archaea, one can find a great variety of other cell wall structures like proteoglycan-like S-layers (Halobacteria), glutaminylglycan (Natronococci), methanochondroitin (Methanosarcina) or double layered cell walls with pseudomurein (Methanothermus and Methanopyrus). The presence of an outermost cellular membrane in the crenarchaeal species Ignicoccus hospitalis already gave indications for an outer membrane similar to Gram-negative bacteria. Although there is just limited data concerning their biochemistry and ultrastructure, recent studies on the euryarchaeal methanogen Methanomassiliicoccus luminyensis, cells of the ARMAN group, and the SM1 euryarchaeon delivered further examples for this exceptional cell envelope type consisting of two membranes. PMID:25505452

  5. The offshore export of sand during exceptional discharge from California rivers

    USGS Publications Warehouse

    Warrick, Jonathan A.; Barnard, Patrick L.

    2012-01-01

    Littoral cells along active tectonic margins receive large inputs of sand and gravel from coastal watersheds and commonly lose this sediment to submarine canyons. One hypothesis is that the majority of coarse (sand and gravel) river sediment discharge will be emplaced within and immediately “resupply” local littoral cells. A competing hypothesis is that the infrequent, large floods that supply the majority of littoral sediment may discharge water-sediment mixtures within negatively buoyant hyperpycnal plumes that transport sediment offshore of the littoral cell. Here we summarize pre- and post-flood surveys of two wave-dominated California (United States) river deltas during record to near-record floods to help evaluate these hypotheses: the 1982–1983 delta at the San Lorenzo River mouth and the 2005 delta at the Santa Clara River mouth. Flood sedimentation at both deltas resulted in several meters of aggradation and hundreds of meters of offshore displacement of isobaths. One substantial difference between these deltas was the thick (>2 m) aggradation of sand on the inner shelf of the Santa Clara River delta that contained substantial amounts (∼50%) of littoral-grade sediment. Once deposited on the inner shelf, only a fraction (∼20%) of this river sand was observed to migrate toward the beach over the following 5 yr. Furthermore, simple hypopycnal plume behavior could not explain deposition of this sand on the inner shelf. Thus, during an exceptional flood a substantial amount of littoral-grade sand was exported offshore of the littoral system at the Santa Clara River mouth—likely from hyperpycnal plume processes—and was deposited on the inner shelf.

  6. Working with Twice-Exceptional African American Students: Information for School Counselors

    ERIC Educational Resources Information Center

    Mayes, Renae D.; Hines, Erik M.; Harris, Paul C.

    2014-01-01

    This qualitative study examined the perceptions, attitudes, and experiences of eight twice-exceptional African American gifted students who attended the same K-12 urban school district in the Midwest. Four major themes emerged--academic supports, personal and social challenges, career worries, and experience with school counselors. Findings…

  7. A Study Exploring Exceptional Education Pre-Service Teachers' Mathematics Anxiety

    ERIC Educational Resources Information Center

    Gresham, Gina

    2010-01-01

    Fifty-two exceptional education pre-service teachers getting a K-6 endorsement were involved in this study that investigated the changes in levels of mathematics anxiety before and after a mathematics methods course for education majors. The changes were measured with respect to the use of manipulatives and other activities to make mathematics…

  8. Common NICU Equipment

    MedlinePlus

    ... care unit (NICU) > Common NICU equipment Common NICU equipment E-mail to a friend Please fill in ... understand how they can help your baby. What equipment is commonly used in the NICU? Providers use ...

  9. Common Cause Failure Modeling

    NASA Technical Reports Server (NTRS)

    Hark, Frank; Britton, Paul; Ring, Robert; Novack, Steven

    2015-01-01

    Space Launch System (SLS) Agenda: Objective; Key Definitions; Calculating Common Cause; Examples; Defense against Common Cause; Impact of varied Common Cause Failure (CCF) and abortability; Response Surface for various CCF Beta; Takeaways.

  10. Common Career Technical Core: Common Standards, Common Vision for CTE

    ERIC Educational Resources Information Center

    Green, Kimberly

    2012-01-01

    This article provides an overview of the National Association of State Directors of Career Technical Education Consortium's (NASDCTEc) Common Career Technical Core (CCTC), a state-led initiative that was created to ensure that career and technical education (CTE) programs are consistent and high quality across the United States. Forty-two states,…

  11. Exceptional structured noncoding RNAs revealed by bacterial metagenome analysis.

    PubMed

    Weinberg, Zasha; Perreault, Jonathan; Meyer, Michelle M; Breaker, Ronald R

    2009-12-03

    Estimates of the total number of bacterial species indicate that existing DNA sequence databases carry only a tiny fraction of the total amount of DNA sequence space represented by this division of life. Indeed, environmental DNA samples have been shown to encode many previously unknown classes of proteins and RNAs. Bioinformatics searches of genomic DNA from bacteria commonly identify new noncoding RNAs (ncRNAs) such as riboswitches. In rare instances, RNAs that exhibit more extensive sequence and structural conservation across a wide range of bacteria are encountered. Given that large structured RNAs are known to carry out complex biochemical functions such as protein synthesis and RNA processing reactions, identifying more RNAs of great size and intricate structure is likely to reveal additional biochemical functions that can be achieved by RNA. We applied an updated computational pipeline to discover ncRNAs that rival the known large ribozymes in size and structural complexity or that are among the most abundant RNAs in bacteria that encode them. These RNAs would have been difficult or impossible to detect without examining environmental DNA sequences, indicating that numerous RNAs with extraordinary size, structural complexity, or other exceptional characteristics remain to be discovered in unexplored sequence space.

  12. It's Major! College Major Selection & Success

    ERIC Educational Resources Information Center

    Byers, Jenny; Mattern, Krista D.; Shaw, Emily J.; Springall, Robert

    2011-01-01

    Presented at the College Board National Forum, October 26, 2011. Choosing a college major is challenging enough, without stopping to consider the impact it has on a student's college experience and career choice. To provide support during this major decision, participants in this session will develop strategies to facilitate students in making an…

  13. Impacts of climate change on the world's most exceptional ecoregions.

    PubMed

    Beaumont, Linda J; Pitman, Andrew; Perkins, Sarah; Zimmermann, Niklaus E; Yoccoz, Nigel G; Thuiller, Wilfried

    2011-02-08

    The current rate of warming due to increases in greenhouse gas (GHG) emissions is very likely unprecedented over the last 10,000 y. Although the majority of countries have adopted the view that global warming must be limited to <2 °C, current GHG emission rates and nonagreement at Copenhagen in December 2009 increase the likelihood of this limit being exceeded by 2100. Extensive evidence has linked major changes in biological systems to 20th century warming. The "Global 200" comprises 238 ecoregions of exceptional biodiversity [Olson DM, Dinerstein E (2002) Ann Mo Bot Gard 89:199-224]. We assess the likelihood that, by 2070, these iconic ecoregions will regularly experience monthly climatic conditions that were extreme in 1961-1990. Using >600 realizations from climate model ensembles, we show that up to 86% of terrestrial and 83% of freshwater ecoregions will be exposed to average monthly temperature patterns >2 SDs (2σ) of the 1961-1990 baseline, including 82% of critically endangered ecoregions. The entire range of 89 ecoregions will experience extreme monthly temperatures with a local warming of <2 °C. Tropical and subtropical ecoregions, and mangroves, face extreme conditions earliest, some with <1 °C warming. In contrast, few ecoregions within Boreal Forests and Tundra biomes will experience such extremes this century. On average, precipitation regimes do not exceed 2σ of the baseline period, although considerable variability exists across the climate realizations. Further, the strength of the correlation between seasonal temperature and precipitation changes over numerous ecoregions. These results suggest many Global 200 ecoregions may be under substantial climatic stress by 2100.

  14. 48 CFR 339.203 - Approval of exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 339.203.... For further information, see paragraphs 4.3, Section 508 Compliance Exceptions, and paragraph...

  15. 48 CFR 339.203 - Approval of exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 339.203.... For further information, see paragraphs 4.3, Section 508 Compliance Exceptions, and paragraph...

  16. Development of candidate gene markers associated to common bacterial blight resistance in common bean

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Common bacterial blight (CBB), caused by Xanthomonas axonopodis pv. phaseoli (Xap), is a major yield-limiting factor of common bean (Phaseolus vulgaris L.) production around the world. Two major CBB-resistant quantitative trait loci (QTL), linked to the sequence characterized amplified region marker...

  17. Common Tests for Arrhythmia

    MedlinePlus

    ... Venous Thromboembolism Aortic Aneurysm More Common Tests for Arrhythmia Updated:Dec 21,2016 Several tests can help ... View an animation of arrhythmia . Common Tests for Arrhythmia Holter monitor (continuous ambulatory electrocardiographic monitor) Suspected arrhythmias ...

  18. Finding Common Ground with the Common Core

    ERIC Educational Resources Information Center

    Moisan, Heidi

    2015-01-01

    This article examines the journey of museum educators at the Chicago History Museum in understanding the Common Core State Standards and implementing them in our work with the school audience. The process raised questions about our teaching philosophy and our responsibility to our audience. Working with colleagues inside and outside of our…

  19. How Common Is the Common Core?

    ERIC Educational Resources Information Center

    Thomas, Amande; Edson, Alden J.

    2014-01-01

    Since the introduction of the Common Core State Standards for Mathematics (CCSSM) in 2010, stakeholders in adopting states have engaged in a variety of activities to understand CCSSM standards and transition from previous state standards. These efforts include research, professional development, assessment and modification of curriculum resources,…

  20. 49 CFR 236.1019 - Main line track exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1019 Main line track exceptions. (a) Scope and procedure. This section pertains exclusively to exceptions from the rule that trackage over which scheduled intercity and...

  1. 49 CFR 236.1019 - Main line track exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1019 Main line track exceptions. (a) Scope and procedure. This section pertains exclusively to exceptions from the rule that trackage over which scheduled intercity and...

  2. 49 CFR 236.1019 - Main line track exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1019 Main line track exceptions. (a) Scope and procedure. This section pertains exclusively to exceptions from the rule that trackage over which scheduled intercity and...

  3. Exceptional Symmetry by Genomic Word : A Statistical Analysis.

    PubMed

    Afreixo, Vera; Rodrigues, João M O S; Bastos, Carlos A C; Tavares, Ana H M P; Silva, Raquel M

    2017-03-01

    Single-strand DNA symmetry is pointed as a universal law observed in the genomes from all living organisms. It is a somewhat broadly defined concept, which has been refined into some more specific measurable effects. Here we discuss the exceptional symmetry effect. Exceptional symmetry is the symmetry effect beyond that expected in independence contexts, and it can be measured for each word, for each equivalent composition group, or globally, combining the effects of all possible words of a given length. Global exceptional symmetry was found in several species, but there are genomic words with no exceptional symmetry effect, whereas others show a very high exceptional symmetry effect. In this work, we discuss a measure to evaluate the exceptional symmetry effect by symmetric word pair, and compare it with others. We present a detailed study of the exceptional symmetry by symmetric pairs and take the CG content into account. We also introduce and discuss the exceptional symmetry profile for the DNA of each organism, and we perform a multiple comparison for 31 genomes: 7 viruses; 5 archaea; 5 bacteria; 14 eukaryotes.

  4. An Exception Handling Service for Software Agent Ensembles

    DTIC Science & Technology

    2004-02-01

    of this project has been to develop technology that enables robust operation in open multi - agent systems (MAS) where we have, in principle, no...problems. 15. NUMBER OF PAGES 123 14. SUBJECT TERMS Software Agents, Exception Handling, Multi - Agent Systems 16. PRICE CODE 17. SECURITY... Multi - agent System Exceptions

  5. University Exceptional Admission during the Republic of China

    ERIC Educational Resources Information Center

    Tao, Li

    2014-01-01

    The stories of many universities' exceptive admission during the republic period of China were widely circulated. The typical example of these universities' exceptional admission was the very product of special historical condition, which had its own characteristics, but also conforms to the general rule, so it can be cited. To select special…

  6. 49 CFR 173.307 - Exceptions for compressed gases.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Exceptions for compressed gases. 173.307 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Gases; Preparation and Packaging § 173.307 Exceptions for compressed gases. (a) The following materials are not subject to the requirements of this subchapter:...

  7. 49 CFR 173.307 - Exceptions for compressed gases.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Exceptions for compressed gases. 173.307 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Gases; Preparation and Packaging § 173.307 Exceptions for compressed gases. (a) The following materials are not subject to the requirements of this subchapter:...

  8. 7 CFR 764.106 - Exceptions to security requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Exceptions to security requirements. 764.106 Section..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Requirements for All Direct Program Loans § 764.106 Exceptions to security requirements. Notwithstanding any other provision of this part, the...

  9. 7 CFR 764.106 - Exceptions to security requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Exceptions to security requirements. 764.106 Section..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Requirements for All Direct Program Loans § 764.106 Exceptions to security requirements. Notwithstanding any other provision of this part, the...

  10. 7 CFR 764.106 - Exceptions to security requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Exceptions to security requirements. 764.106 Section..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Requirements for All Direct Program Loans § 764.106 Exceptions to security requirements. Notwithstanding any other provision of this part, the...

  11. 7 CFR 764.106 - Exceptions to security requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Exceptions to security requirements. 764.106 Section..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Requirements for All Direct Program Loans § 764.106 Exceptions to security requirements. Notwithstanding any other provision of this part, the...

  12. 7 CFR 764.106 - Exceptions to security requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Exceptions to security requirements. 764.106 Section..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Requirements for All Direct Program Loans § 764.106 Exceptions to security requirements. Notwithstanding any other provision of this part, the...

  13. 14 CFR 61.110 - Night flying exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Night flying exceptions. 61.110 Section 61... flying exceptions. (a) Subject to the limitations of paragraph (b) of this section, a person is not...: (1) May be issued a pilot certificate with a limitation “Night flying prohibited”; and (2)...

  14. 14 CFR 61.110 - Night flying exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Night flying exceptions. 61.110 Section 61... flying exceptions. (a) Subject to the limitations of paragraph (b) of this section, a person is not...: (1) May be issued a pilot certificate with a limitation “Night flying prohibited”; and (2)...

  15. 14 CFR 61.110 - Night flying exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Night flying exceptions. 61.110 Section 61... flying exceptions. (a) Subject to the limitations of paragraph (b) of this section, a person is not...: (1) May be issued a pilot certificate with a limitation “Night flying prohibited”; and (2)...

  16. 14 CFR 61.110 - Night flying exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Night flying exceptions. 61.110 Section 61... flying exceptions. (a) Subject to the limitations of paragraph (b) of this section, a person is not...: (1) May be issued a pilot certificate with a limitation “Night flying prohibited”; and (2)...

  17. 14 CFR 61.110 - Night flying exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Night flying exceptions. 61.110 Section 61... flying exceptions. (a) Subject to the limitations of paragraph (b) of this section, a person is not...: (1) May be issued a pilot certificate with a limitation “Night flying prohibited”; and (2)...

  18. 36 CFR 27.4 - Variances and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Variances and exceptions. 27.4 Section 27.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CAPE COD NATIONAL SEASHORE; ZONING STANDARDS § 27.4 Variances and exceptions. (a) Zoning bylaws...

  19. 36 CFR 27.4 - Variances and exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Variances and exceptions. 27.4 Section 27.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CAPE COD NATIONAL SEASHORE; ZONING STANDARDS § 27.4 Variances and exceptions. (a) Zoning bylaws...

  20. 36 CFR 27.4 - Variances and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Variances and exceptions. 27.4 Section 27.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CAPE COD NATIONAL SEASHORE; ZONING STANDARDS § 27.4 Variances and exceptions. (a) Zoning bylaws...