Mobilising the Commodity Chain Concept in the Politics of Food and Farming

ERIC Educational Resources Information Center

Jackson, Peter; Ward, Neil; Russell, Polly

2006-01-01

Focusing on the concept of "commodity chains" within the food industry, this paper analyses the term's widespread and variable usage in both academic and policy-orientated work. Despite recent criticisms, the concept has retained its popular appeal alongside competing metaphors such as networks, circuits and assemblages. Examining the…

Uncovering the fruit bat bushmeat commodity chain and the true extent of fruit bat hunting in Ghana, West Africa

PubMed Central

Kamins, A.O.; Restif, O.; Ntiamoa-Baidu, Y.; Suu-Ire, R.; Hayman, D.T.S.; Cunningham, A.A.; Wood, J.L.N.; Rowcliffe, J.M.

2011-01-01

Harvesting, consumption and trade of bushmeat are important causes of both biodiversity loss and potential zoonotic disease emergence. In order to identify possible ways to mitigate these threats, it is essential to improve our understanding of the mechanisms by which bushmeat gets from the site of capture to the consumer’s table. In this paper we highlight the previously unrecognized scale of hunting of the African straw-colored fruit bat, Eidolon helvum, a species which is important in both ecological and public health contexts, and describe the commodity chain in southern Ghana for its trade. Based on interviews with 551 Ghanaians, including bat hunters, vendors and consumers, we estimate that a minimum of 128,000 E. helvum bats are sold each year through a commodity chain stretching up to 400 km and involving multiple vendors. Unlike the general bushmeat trade in Ghana, where animals are sold in both specialized bushmeat markets and in restaurants, E. helvum is sold primarily in marketplaces; many bats are also kept by hunters for personal consumption. The offtake estimated in this paper raises serious conservation concerns, while the commodity chain identified in this study may offer possible points for management intervention. The separation of the E. helvum commodity chain from that of other bushmeat highlights the need for species-specific research in this area, particularly for bats, whose status as bushmeat is largely unknown. PMID:22514356

Uncovering the fruit bat bushmeat commodity chain and the true extent of fruit bat hunting in Ghana, West Africa.

PubMed

Kamins, A O; Restif, O; Ntiamoa-Baidu, Y; Suu-Ire, R; Hayman, D T S; Cunningham, A A; Wood, J L N; Rowcliffe, J M

2011-12-01

Harvesting, consumption and trade of bushmeat are important causes of both biodiversity loss and potential zoonotic disease emergence. In order to identify possible ways to mitigate these threats, it is essential to improve our understanding of the mechanisms by which bushmeat gets from the site of capture to the consumer's table. In this paper we highlight the previously unrecognized scale of hunting of the African straw-colored fruit bat, Eidolon helvum, a species which is important in both ecological and public health contexts, and describe the commodity chain in southern Ghana for its trade. Based on interviews with 551 Ghanaians, including bat hunters, vendors and consumers, we estimate that a minimum of 128,000 E. helvum bats are sold each year through a commodity chain stretching up to 400 km and involving multiple vendors. Unlike the general bushmeat trade in Ghana, where animals are sold in both specialized bushmeat markets and in restaurants, E. helvum is sold primarily in marketplaces; many bats are also kept by hunters for personal consumption. The offtake estimated in this paper raises serious conservation concerns, while the commodity chain identified in this study may offer possible points for management intervention. The separation of the E. helvum commodity chain from that of other bushmeat highlights the need for species-specific research in this area, particularly for bats, whose status as bushmeat is largely unknown.

17 CFR 75.20 - Program for compliance; reporting.

Code of Federal Regulations, 2014 CFR

2014-04-01

... two calendar years shall maintain records that include: (1) Documentation of the exclusions or...; reporting. 75.20 Section 75.20 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... (a) of this section, at a minimum, shall include: (1) Written policies and procedures reasonably...

Improving agricultural commodity supply-chain to promote economic activities in rural area

NASA Astrophysics Data System (ADS)

Padjung, R.

2018-05-01

Long supply chain of agricultural commodities has become concern to governments particularly in large countries such as Indonesia as it causes high price disparity between farm-gate and retailer. Policies to overcome such problem are usually by shortening the chain, by which farmers sell the products directly to retailers. Using an action research in AEDEF (Aceh Economic Development Financing Facilities) Program, conducted in the province of Nangro Aceh Darussalam (NAD) Indonesia, the paper shows that shortening the commodity supply chain is not the best solution to such problem, as it causes loss of jobs in the villages. High price disparity between farm-gate and retailer is not necessary brought about by long supply-chain but by the efficiency of the chain instead. Efficiency of the chain can be improved by creating enabling business environment such that every actors and players work in a fair manner. This can be achieved by transparency in price and quality grade. With development achieved in Information and Communication Technology (ICT), having a good and reliable flow of such information is not difficult. In addition to information flow, the availability and quality of infrastructure to support flow of goods from farm-gate to end-user is of reasonably important.

Pilot assessment of supply chains for pharmaceuticals and medical commodities for malaria, tuberculosis and HIV infection in Ethiopia.

PubMed

Daniel, Gabriel; Tegegnework, Hailu; Demissie, Tsion; Reithinger, Richard

2012-01-01

To obtain preliminary data on the drug supply management system in Ethiopia, selected facilities were assessed for the availability of essential drugs and commodities for malaria, TB and HIV. Of the 48 surveyed hospitals and health centers, 9 (19%), 9 (19%) and 10 (21%) did not have malaria, TB or HIV drugs, respectively. Similarly, of 27 health posts, 9 (33%) and 6 (22%) did not have rapid diagnostic tests and antimalarial drugs, respectively. The findings indicated an inadequate availability of essential drugs and commodities in the surveyed facilities as well as weaknesses in human resources and training. Assessments of commodity supply chains to ensure operational program success and impact are important. Published by Elsevier Ltd.

Bread in the Economy of Qualities: The Creative Reconstitution of the Canada-UK Commodity Chain for Wheat

ERIC Educational Resources Information Center

Magnan, Andre

2011-01-01

This article traces the creative reconstitution of the Canada-UK wheat-bread commodity chain since the 1990s. In the mid-1990s, the Canadian Wheat Board (CWB) and a British bakery, Warburtons, pioneered an innovative identity-preserved sourcing relationship that ties contracted prairie wheat growers to consumers of premium bread in the United…

The use of importance and performance analysis (IPA) to evaluate effectiveness of the forward auction market agro commodities: A case study

NASA Astrophysics Data System (ADS)

Wulansari, Dwi Ratna; Sutopo, Wahyudi; Hisjam, Muh.

2018-02-01

The empowering auction market for commodities in East Java Province is one of five auction market revitalization programs conducted by the Republic of Indonesia c.q. Ministry of Trading started in 2014. One of the districts in East Java Province, namely Magetan District utilizes the commodity auction market to improve the competitiveness of their agricultural industry by shortening the supply chain. The Magetan District needs to evaluate their support for farmers or farmer groups to participate in the forward auction market (FAM). Implementation of the FAM commodities is divided into three main processes, namely pre-auction, auction, and post-auction. The auction market is organized to shorten the trading chain. Implementation of the FAM requires good planning, among Seller (namely Farmer or Farmer Group), organizer of Auction (namely Commodity Auction Company), Buyer, and Local Government (namely the farmer facilitator). This article is aimed to develop the instrument of a Performance Measurement Model Using Important and Performance Analysis (IPA) for Improving the FAM Effectiveness of Agro Commodity from Magetan District with Supply Chain Management approach. IPA is implemented at pre-auction, auction, and post-auction. The IPA model results in the diagram to decide the strategies in improving the FAM effectiveness, and then it can encourage farmers to improve welfare and realize the competitiveness of the auctioneer.

Production of Odd-Carbon Dicarboxylic Acids in Escherichia coli Using an Engineered Biotin-Fatty Acid Biosynthetic Pathway.

PubMed

Haushalter, Robert W; Phelan, Ryan M; Hoh, Kristina M; Su, Cindy; Wang, George; Baidoo, Edward E K; Keasling, Jay D

2017-04-05

Dicarboxylic acids are commodity chemicals used in the production of plastics, polyesters, nylons, fragrances, and medications. Bio-based routes to dicarboxylic acids are gaining attention due to environmental concerns about petroleum-based production of these compounds. Some industrial applications require dicarboxylic acids with specific carbon chain lengths, including odd-carbon species. Biosynthetic pathways involving cytochrome P450-catalyzed oxidation of fatty acids in yeast and bacteria have been reported, but these systems produce almost exclusively even-carbon species. Here we report a novel pathway to odd-carbon dicarboxylic acids directly from glucose in Escherichia coli by employing an engineered pathway combining enzymes from biotin and fatty acid synthesis. Optimization of the pathway will lead to industrial strains for the production of valuable odd-carbon diacids.

Applying commodity chain analysis to changing modes of alcohol supply in a developing country.

PubMed

Jernigan, D H

2000-12-01

Development sociology has used global commodity chains as one way of analyzing the dynamics of power and profit-taking in globalized production networks made up of multiple firms and occurring in multiple national settings. A substantial portion of the alcohol supply in developing countries is now produced through such production networks. Particularly in the beer and spirits trade, a small number of transnational firms control networks of local producers, importers, advertisers and distributors. These networks serve to embed transnational or transnationally backed brands in the local culture, using the tools of market research, product design and marketing to influence local drinking practices. Case materials from Malaysia's beer industry help to illustrate how the transnational firms dominate in those links of the commodity chain in which monopoly or oligopoly control is most likely to be found: the design/recipe and marketing/advertising nodes. Their control of the commodity chains and extraction of monopoly or oligopoly profits from them places substantial resources and influence over drinking settings and practices in foreign hands. The impact of this influence on state efficacy and autonomy in setting alcohol policy is an important subject for future research on the creation and implementation of effective alcohol policies in developing societies.

Costs of food waste along the value chain: evidence from South Africa.

PubMed

Nahman, Anton; de Lange, Willem

2013-11-01

In a previous paper (Nahman et al., 2012), the authors estimated the costs of household food waste in South Africa, based on the market value of the wasted food (edible portion only), as well as the costs of disposal to landfill. In this paper, we extend the analysis by assessing the costs of edible food waste throughout the entire food value chain, from agricultural production through to consumption at the household level. First, food waste at each stage of the value chain was quantified in physical units (tonnes) for various food commodity groups. Then, weighted average representative prices (per tonne) were estimated for each commodity group at each stage of the value chain. Finally, prices were multiplied by quantities, and the resulting values were aggregated across the value chain for all commodity groups. In this way, the total cost of food waste across the food value chain in South Africa was estimated at R61.5 billion per annum (approximately US$7.7 billion); equivalent to 2.1% of South Africa's annual gross domestic product. The bulk of this cost arises from the processing and distribution stages of the fruit and vegetable value chain, as well as the agricultural production and distribution stages of the meat value chain. These results therefore provide an indication of where interventions aimed at reducing food waste should be targeted. Copyright © 2013 Elsevier Ltd. All rights reserved.

29 CFR 780.611 - Workweek exclusively in agriculture.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Workweek exclusively in agriculture. 780.611 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

29 CFR 780.611 - Workweek exclusively in agriculture.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 3 2014-07-01 2014-07-01 false Workweek exclusively in agriculture. 780.611 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

29 CFR 780.611 - Workweek exclusively in agriculture.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 3 2012-07-01 2012-07-01 false Workweek exclusively in agriculture. 780.611 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

29 CFR 780.611 - Workweek exclusively in agriculture.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 3 2013-07-01 2013-07-01 false Workweek exclusively in agriculture. 780.611 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

29 CFR 780.611 - Workweek exclusively in agriculture.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Workweek exclusively in agriculture. 780.611 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

Materials Flow through Industry Supply Chain Modeling Tool | Advanced

Science.gov Websites

efficiency. It also performs supply chain scale analyses to quantify the impacts and benefits of next , read Evaluating opportunities to improve material and energy impacts in commodity supply chains

Governance Options to Enhance Ecosystem Services in Cocoa, Soy, Tropical Timber and Palm Oil Value Chains.

PubMed

Ingram, Verina; van den Berg, Jolanda; van Oorschot, Mark; Arets, Eric; Judge, Lucas

2018-02-06

Dutch policies have advocated sustainable commodity value chains, which have implications for the landscapes from which these commodities originate. This study examines governance and policy options for sustainability in terms of how ecosystem services are addressed in cocoa, soy, tropical timber and palm oil value chains with Dutch links. A range of policies addressing ecosystem services were identified, from market governance (certification, payments for ecosystem services) to multi-actor platforms (roundtables) and public governance (policies and regulations). An analysis of policy narratives and interviews identified if and how ecosystem services are addressed within value chains and policies; how the concept has been incorporated into value chain governance; and which governance options are available. The Dutch government was found to take a steering but indirect role in all the cases, primarily through supporting, financing, facilitating and partnering policies. Interventions mainly from end-of-chain stakeholders located in processing and consumption countries resulted in new market governance, notably voluntary sustainability standards. These have been successful in creating awareness of some ecosystem services and bringing stakeholders together. However, they have not fully addressed all ecosystem services or stakeholders, thus failing to increase the sustainability of value chains or of the landscapes of origin. We argue that chains sourced in tropical landscapes may be governed more effectively for sustainability if voluntary, market policy tools and governance arrangements have more integrated goals that take account of sourcing landscapes and impacts along the entire value chain. Given the international nature of these commodities. These findings have significance for debates on public-private approaches to value chain and landscape governance.

International trade standards for commodities and products derived from animals: the need for a system that integrates food safety and animal disease risk management.

PubMed

Thomson, G R; Penrith, M-L; Atkinson, M W; Thalwitzer, S; Mancuso, A; Atkinson, S J; Osofsky, S A

2013-12-01

A case is made for greater emphasis to be placed on value chain management as an alternative to geographically based disease risk mitigation for trade in commodities and products derived from animals. The geographic approach is dependent upon achievement of freedom in countries or zones from infectious agents that cause so-called transboundary animal diseases, while value chain-based risk management depends upon mitigation of animal disease hazards potentially associated with specific commodities or products irrespective of the locality of production. This commodity-specific approach is founded on the same principles upon which international food safety standards are based, viz. hazard analysis critical control points (HACCP). Broader acceptance of a value chain approach enables animal disease risk management to be combined with food safety management by the integration of commodity-based trade and HACCP methodologies and thereby facilitates 'farm to fork' quality assurance. The latter is increasingly recognized as indispensable to food safety assurance and is therefore a pre-condition to safe trade. The biological principles upon which HACCP and commodity-based trade are based are essentially identical, potentially simplifying sanitary control in contrast to current separate international sanitary standards for food safety and animal disease risks that are difficult to reconcile. A value chain approach would not only enable more effective integration of food safety and animal disease risk management of foodstuffs derived from animals but would also ameliorate adverse environmental and associated socio-economic consequences of current sanitary standards based on the geographic distribution of animal infections. This is especially the case where vast veterinary cordon fencing systems are relied upon to separate livestock and wildlife as is the case in much of southern Africa. A value chain approach would thus be particularly beneficial to under-developed regions of the world such as southern Africa specifically and sub-Saharan Africa more generally where it would reduce incompatibility between attempts to expand and commercialize livestock production and the need to conserve the subcontinent's unparalleled wildlife and wilderness resources. © 2013 Blackwell Verlag GmbH.

29 CFR 780.317 - Man-day exclusion.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Man-day exclusion. 780.317 Section 780.317 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED...

29 CFR 780.309 - Man-day exclusion.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Man-day exclusion. 780.309 Section 780.309 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED...

Production of Odd-Carbon Dicarboxylic Acids in Escherichia coli Using an Engineered Biotin–Fatty Acid Biosynthetic Pathway

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haushalter, Robert W.; Phelan, Ryan M.; Hoh, Kristina M.

Dicarboxylic acids are commodity chemicals used in the production of plastics, polyesters, nylons, fragrances, and medications. Bio-based routes to dicarboxylic acids are gaining attention due to environmental concerns about petroleum-based production of these compounds. Some industrial applications require dicarboxylic acids with specific carbon chain lengths, including odd-carbon species. Biosynthetic pathways involving cytochrome P450-catalyzed oxidation of fatty acids in yeast and bacteria have been reported, but these systems produce almost exclusively even-carbon species. Here in this paper we report a novel pathway to odd-carbon dicarboxylic acids directly from glucose in Escherichia coli by employing an engineered pathway combining enzymes from biotinmore » and fatty acid synthesis. Optimization of the pathway will lead to industrial strains for the production of valuable odd-carbon diacids.« less

Global stocks of selected mineral-based commodities

USGS Publications Warehouse

Wilburn, David R.; Bleiwas, Donald I.; Karl, Nick A.

2016-12-05

IntroductionThe U.S. Geological Survey, National Minerals Information Center, analyzes mineral and metal supply chains by identifying and describing major components of mineral and material flows from ore extraction, through intermediate forms, to a final product. This report focuses on an important component of the world’s supply chain: the amounts and global distribution of major consumer, producer, and exchange stocks of selected mineral commodities. In this report, the term “stock” is used instead of “inventory” and refers to accumulations of mined ore, intermediate products, and refined mineral-based commodities that are in a form that meets the agreed-upon specifications of a buyer or processor of intermediate products. These may include certain ores such as bauxite, concentrates, smelter products, and refined metals. Materials sometimes referred to as inventory for accounting purposes, such as ore contained in a deposit or in a leach pile, or materials that need to be further processed before they can be shipped to a consumer, are not considered. Stocks may be held (owned) by consumers, governments, investors, producers, and traders. They may serve as (1) a means to achieve economic, social, and strategic goals through government policies; (2) a secure source of supply to meet demand and to mitigate potential shortages in the supply chain; (3) a hedge to mitigate price volatility; and (4) vehicles for speculative investment.The paucity and uneven reliability of data for stocks of ores and concentrates and for material held by producers, consumers, and merchants hinder the accurate estimating of the size and distribution of this portion of the supply chain for certain commodities. This paper reviews the more visible stocks held in commodity exchange warehouses distributed throughout the world.

On Farm and Packhouse: Employment at the Bottom of a Global Value Chain

ERIC Educational Resources Information Center

Dolan, Catherine S.

2004-01-01

The fresh vegetables commodity chain linking Kenyan producers with United Kingdom (UK) consumers employs significant numbers of workers in production and processing. This chain is dominated by UK retailers that determine the production imperatives of Kenyan firms upstream in the chain and, indirectly the employment strategies they adopt. This…

17 CFR 240.15Ba2-2 - Application for registration of non-bank municipal securities dealers whose business is...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Application for registration of non-bank municipal securities dealers whose business is exclusively intrastate. 240.15Ba2-2... registration of non-bank municipal securities dealers whose business is exclusively intrastate. (a) An...

Incorporating Agroforestry Approaches into Commodity Value Chains

NASA Astrophysics Data System (ADS)

Millard, Edward

2011-08-01

The productivity of tropical agricultural commodities is affected by the health of the ecosystem. Shade tolerant crops such as coffee and cocoa benefit from environmental services provided by forested landscapes, enabling landscape design that meets biodiversity conservation and economic needs. What can motivate farmers to apply and maintain such landscape approaches? Rather than rely on a proliferation of externally funded projects new opportunities are emerging through the international market that buys these commodities. As part of their growing commitment to sustainable supply chains, major companies are supporting agroforestry approaches and requiring producers and traders to demonstrate that the source of their commodities complies with a set of principles that conserves forested landscapes and improves local livelihoods. The paper presents examples of international companies that are moving in this direction, analyzes why and how they are doing it and discusses the impact that has been measured in coffee and cocoa communities in Latin America and Africa. It particularly considers the role of standards and certification systems as a driver of this commitment to promote profitable operations, environmental conservation and social responsibility throughout the coffee and cocoa value chains. Such approaches are already being taken to scale and are no longer operating only in small niches of the market but the paper also considers the limitations to growth in this market-based approach.

Incorporating agroforestry approaches into commodity value chains.

PubMed

Millard, Edward

2011-08-01

The productivity of tropical agricultural commodities is affected by the health of the ecosystem. Shade tolerant crops such as coffee and cocoa benefit from environmental services provided by forested landscapes, enabling landscape design that meets biodiversity conservation and economic needs. What can motivate farmers to apply and maintain such landscape approaches? Rather than rely on a proliferation of externally funded projects new opportunities are emerging through the international market that buys these commodities. As part of their growing commitment to sustainable supply chains, major companies are supporting agroforestry approaches and requiring producers and traders to demonstrate that the source of their commodities complies with a set of principles that conserves forested landscapes and improves local livelihoods. The paper presents examples of international companies that are moving in this direction, analyzes why and how they are doing it and discusses the impact that has been measured in coffee and cocoa communities in Latin America and Africa. It particularly considers the role of standards and certification systems as a driver of this commitment to promote profitable operations, environmental conservation and social responsibility throughout the coffee and cocoa value chains. Such approaches are already being taken to scale and are no longer operating only in small niches of the market but the paper also considers the limitations to growth in this market-based approach.

Towards a Tool for Malaria Supply Chain Management Improvement in Rural Ghana.

PubMed

Carlo, Lorena; Bakken, Suzanne; Mamykina, Lena; Kodie, Richmond; Kanter, Andrew S

2015-01-01

The maintenance of adequate quantities of antimalarial medicines and rapid diagnostic tests (RDTs) at health facilities in rural areas of sub-Saharan Africa is a challenging task because of poor supply chain management. Antimalarial stock-outs in the communities could lead patients (that need to travel long distances to get medications) to remain untreated, develop severe malaria and die. A prototype to improve the management of health commodities in rural Ghana through the visualization of current stock levels and the forecasting of commodities is proposed.

An Internet portal dedicated to pig production and wild suids in the tropics: PigTrop web site http://pigtrop.cirad.fr.

PubMed

Porphyre, Vincent; Gourment, Cyricce; Erwin, Thierry; Nouaille, Christine

2006-10-01

Considering that a wide access to updated and relevant data is a key point for livestock development and research improvement in tropics, The PigTrop web site (http://pigtrop.cirad.fr) is dedicated to pig production and pork commodity chains in developing countries. It mainly addresses stakeholders involved in the pig commodity chain, but also researchers, students, or development agencies with an interest in tropical pig breeding. It is run by the French Agricultural Research Centre for International Development (CIRAD).

The UN Commission on Life Saving Commodities 3 years on: global progress update and results of a multicountry assessment.

PubMed

Pronyk, Paul M; Nemser, Bennett; Maliqi, Blerta; Springstubb, Nora; Sera, Diana; Karimov, Rouslan; Katwan, Elizabeth; Walter, Benedicte; Bijleveld, Pascal

2016-04-01

In September, 2012, the UN Commission on Life Saving Commodities (UNCoLSC) outlined a plan to expand availability and access to 13 life saving commodities. We profile global and country progress against these recommendations between 2012 and 2015. For 12 countries in sub-Saharan Africa that were off-track to achieve the Millennium Development Goals for maternal and child survival, we reviewed key documents and reference data, and conducted interviews with ministry staff and partners to assess the status of the UNCoLSC recommendations. The RMNCH fund provided short-term catalytic financing to support country plans to advance the commodity agenda, with activities coded by UNCoLSC recommendation. Our network of technical resource teams identified, addressed, and monitored progress against cross-cutting commodity-related challenges that needed coordinated global action. In 2014 and 2015, child and maternal health commodities had fewer bottlenecks than reproductive and neonatal commodities. Common bottlenecks included regulatory challenges (ten of 12 countries); poor quality assurance (11 of 12 countries); insufficient staff training (more than half of facilities on average); and weak supply chains systems (11 of 12 countries), with stock-outs of priority commodities in about 40% of facilities on average. The RMNCH fund committed US$175·7 million to 19 countries to support strategies addressing crucial gaps. $68·2 million (39·0%) of the funds supported systems-strengthening interventions with the remainder split across reproductive, maternal, newborn, and child health. Health worker training ($88·6 million, 50·4%), supply chain ($53·3 million, 30·0%), and demand generation ($21·1 million, 12·0%) were the major topics of focus. All priority commodities are now listed in the WHO Essential Medicines List; appropriate price reductions were secured; quality manufacturing was improved; a fast-track registration mechanism for prequalified products was established; and methods were developed for advocacy, quantification, demand generation, supply chain, and provider training. Slower progress was evident around regulatory harmonisation and quality assurance. Much work is needed to achieve full implementation of the UNCoLSC recommendations. Coordinated efforts to secure price reductions beyond the 13 commodities and improve regulatory efficiency, quality, and supply chains are still needed alongside broader dissemination of work products. Governments of Norway (NORAD) and the UK (DFID). Copyright © 2015 World Health Organization; licensee Elsevier. This is an Open Access article published without any waiver of WHO's privileges and immunities under international law, convention, or agreement. This Article should not be reproduced for use in association with the promotion of commercial products, services, or any legal entity. There should be no suggestion that WHO endorses any specific organisation or products. The use of the WHO logo is not permitted. This notice should be preserved along with the Article's original URL.

Bayesian Networks to Compare Pest Control Interventions on Commodities Along Agricultural Production Chains.

PubMed

Holt, J; Leach, A W; Johnson, S; Tu, D M; Nhu, D T; Anh, N T; Quinlan, M M; Whittle, P J L; Mengersen, K; Mumford, J D

2018-02-01

The production of an agricultural commodity involves a sequence of processes: planting/growing, harvesting, sorting/grading, postharvest treatment, packing, and exporting. A Bayesian network has been developed to represent the level of potential infestation of an agricultural commodity by a specified pest along an agricultural production chain. It reflects the dependency of this infestation on the predicted level of pest challenge, the anticipated susceptibility of the commodity to the pest, the level of impact from pest control measures as designed, and any variation from that due to uncertainty in measure efficacy. The objective of this Bayesian network is to facilitate agreement between national governments of the exporters and importers on a set of phytosanitary measures to meet specific phytosanitary measure requirements to achieve target levels of protection against regulated pests. The model can be used to compare the performance of different combinations of measures under different scenarios of pest challenge, making use of available measure performance data. A case study is presented using a model developed for a fruit fly pest on dragon fruit in Vietnam; the model parameters and results are illustrative and do not imply a particular level of fruit fly infestation of these exports; rather, they provide the most likely, alternative, or worst-case scenarios of the impact of measures. As a means to facilitate agreement for trade, the model provides a framework to support communication between exporters and importers about any differences in perceptions of the risk reduction achieved by pest control measures deployed during the commodity production chain. © 2017 Society for Risk Analysis.

17 CFR 240.13p-1 - Requirement of report regarding disclosure of registrant's supply chain information regarding...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Requirement of report regarding disclosure of registrant's supply chain information regarding conflict minerals. 240.13p-1 Section...'s supply chain information regarding conflict minerals. Every registrant that files reports with the...

17 CFR 240.13p-1 - Requirement of report regarding disclosure of registrant's supply chain information regarding...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Requirement of report regarding disclosure of registrant's supply chain information regarding conflict minerals. 240.13p-1 Section...'s supply chain information regarding conflict minerals. Every registrant that files reports with the...

75 FR 29307 - Web Based Supply Chain Management Commodity Offer Form, Paperwork Collection Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-25

... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service [Doc. No FV10-CP-01, AMS-FV-10-0041] Web... collection request is required for the implementation of a new system named Web Based Supply Chain Management...-2782. Mail: David Tuckwiller, Project Manager, Web Based Supply Chain Management System, Agricultural...

Vehicle to vehicle communications for trucks.

DOT National Transportation Integrated Search

2014-01-01

The trucking industry is a critical component of American commerce. The American : Trucking Association estimates that over 80 percent of U.S. communities depend : exclusively on trucking for delivery of their goods and commodities

Stochastic thermodynamics for Ising chain and symmetric exclusion process.

PubMed

Toral, R; Van den Broeck, C; Escaff, D; Lindenberg, Katja

2017-03-01

We verify the finite-time fluctuation theorem for a linear Ising chain in contact with heat reservoirs at its ends. Analytic results are derived for a chain consisting of two spins. The system can be mapped onto a model for particle transport, namely, the symmetric exclusion process in contact with thermal and particle reservoirs. We modify the symmetric exclusion process to represent a thermal engine and reproduce universal features of the efficiency at maximum power.

48 CFR 239.7305 - Exclusion and limitation on disclosure.

Code of Federal Regulations, 2014 CFR

2014-10-01

... TECHNOLOGY Requirements for Information Relating to Supply Chain Risk 239.7305 Exclusion and limitation on... accordance with the requirements of 10 U.S.C. 2319, for the purpose of reducing supply chain risk in the... an evaluation factor providing for the consideration of supply chain risk in the evaluation of...

Integrated supply chain design for commodity chemicals production via woody biomass fast pyrolysis and upgrading.

PubMed

Zhang, Yanan; Hu, Guiping; Brown, Robert C

2014-04-01

This study investigates the optimal supply chain design for commodity chemicals (BTX, etc.) production via woody biomass fast pyrolysis and hydroprocessing pathway. The locations and capacities of distributed preprocessing hubs and integrated biorefinery facilities are optimized with a mixed integer linear programming model. In this integrated supply chain system, decisions on the biomass chipping methods (roadside chipping vs. facility chipping) are also explored. The economic objective of the supply chain model is to maximize the profit for a 20-year chemicals production system. In addition to the economic objective, the model also incorporates an environmental objective of minimizing life cycle greenhouse gas emissions, analyzing the trade-off between the economic and environmental considerations. The capital cost, operating cost, and revenues for the biorefinery facilities are based on techno-economic analysis, and the proposed approach is illustrated through a case study of Minnesota, with Minneapolis-St. Paul serving as the chemicals distribution hub. Copyright © 2014 Elsevier Ltd. All rights reserved.

Agrofuels capitalism: a view from political economy.

PubMed

White, Ben; Dasgupta, Anirban

2010-01-01

This article considers the global expansion of agrofuels feedstock production from a political economy perspective. It considers and dismisses the environmental and pro-poor developmental justifications attached to agrofuels. To local populations and direct producers, the specific destination of the crop as fuel, food, cosmetics or other final uses in faraway places is probably of less interest than the forms of (direct or indirect) appropriation of their land and the forms of their insertion or exclusion as producers in global commodity chains. Global demand for both agrofuels and food is stimulating new forms (or the resurgence of old forms) of corporate land grabbing and expropriation, and of incorporation of smallholders in contracted production. Drawing both on recent studies on agrofuels expansion and on the political economy literature on agrarian transition and capitalism in agriculture, this article raises the question whether "agrofuels capitalism" is in any way essentially different from other forms of capitalist agrarian monocrop production, and in turn whether the agrarian transitions involved require new tools of analysis.

Nitrogen surplus: An environmental performance indicator for sustainable food supply chains

USDA-ARS?s Scientific Manuscript database

Nitrogen pollution and negative impacts on human and environmental health are embodied in crop commodities traded domestically and internationally. Food supply chain companies can play a catalytic role in reducing that burden by helping to decrease the environmental nitrogen load from agriculture. T...

Ecosystem service information to benefit sustainability standards for commodity supply chains.

PubMed

Chaplin-Kramer, Rebecca; Jonell, Malin; Guerry, Anne; Lambin, Eric F; Morgan, Alexis J; Pennington, Derric; Smith, Nathan; Franch, Jane Atkins; Polasky, Stephen

2015-10-01

The growing base of information about ecosystem services generated by ecologists, economists, and other scientists could improve the implementation, monitoring, and evaluation of commodity-sourcing standards being adopted by corporations to mitigate risk in their supply chains and achieve sustainability goals. This review examines various ways that information about ecosystem services could facilitate compliance with and auditing of commodity-sourcing standards. We also identify gaps in the current state of knowledge on the ecological effectiveness of sustainability standards and demonstrate how ecosystem-service information could complement existing monitoring efforts to build credible evidence. This paper is a call to the ecosystem-service scientists to engage in this decision context and tailor the information they are generating to the needs of the standards community, which we argue would offer greater efficiency of standards implementation for producers and enhanced effectiveness for standard scheme owners and corporations, and should thus lead to more sustainable outcomes for people and nature. © 2015 New York Academy of Sciences.

Estimating the Benefits of the Air Force Purchasing and Supply Chain Management Initiative

DTIC Science & Technology

2008-01-01

sector, known as strategic sourcing.6 The Customer Relationship Management initiative ( CRM ) pro- vides a single customer point of contact for all... Customer Relationship Management initiative. commodity council A term used to describe a cross-functional sourc- ing group charged with formulating a...initiative has four major components, all based on commercial best practices (Gabreski, 2004): commodity councils customer relationship management

Malaria rapid diagnostic test transport and storage conditions in Burkina Faso, Senegal, Ethiopia and the Philippines

PubMed Central

2012-01-01

Background As more point of care diagnostics become available, the need to transport and store perishable medical commodities to remote locations increases. As with other diagnostics, malaria rapid diagnostic tests (RDTs) must be highly reliable at point of use, but exposure to adverse environmental conditions during distribution has the potential to degrade tests and accuracy. In remote locations, poor quality diagnostics and drugs may have significant negative health impact that is not readily detectable by routine monitoring. This study assessed temperature and humidity throughout supply chains used to transport and store health commodities, such as RDTs. Methods Monitoring devices capable of recording temperature and humidity were deployed to Burkina Faso (8), Senegal (10), Ethiopia (13) and the Philippines (6) over a 13-month period. The devices travelled through government supply chains, usually alongside RDTs, to health facilities where RDTs are stored, distributed and used. The recording period spanned just over a year, in order to avoid any biases related to seasonal temperature variations. Results In the four countries, storage and transport temperatures regularly exceeded 30.0°C; maximum humidity level recorded was above 94% for the four countries. In three of the four countries, temperatures recorded at central storage facilities exceeded pharmaceutical storage standards for over 20% of the time, in another case for a majority of the time; and sometimes exceeded storage temperatures at peripheral sites. Conclusions Malaria RDTs were regularly exposed to temperatures above recommended limits for many commercially-available RDTs and other medical commodities such as drugs, but rarely exceeded the recommended storage limits for particular products in use in these countries. The results underline the need to select RDTs, and other commodities, according to expected field conditions, actively manage the environmental conditions in supply chains in tropical and sub-tropical climates. This would benefit from a re-visit of current global standards on stability of medical commodities based in tropical and sub-tropical climatic zones. PMID:23217104

Malaria rapid diagnostic test transport and storage conditions in Burkina Faso, Senegal, Ethiopia and the Philippines.

PubMed

Albertini, Audrey; Lee, Evan; Coulibaly, Sheick Oumar; Sleshi, Markos; Faye, Babacar; Mationg, Mary Lorraine; Ouedraogo, Kadi; Tsadik, Abeba G; Feleke, Sendeaw Maksha; Diallo, Ibrahima; Gaye, Oumar; Luchavez, Jennifer; Bennett, Jessica; Bell, David

2012-12-06

As more point of care diagnostics become available, the need to transport and store perishable medical commodities to remote locations increases. As with other diagnostics, malaria rapid diagnostic tests (RDTs) must be highly reliable at point of use, but exposure to adverse environmental conditions during distribution has the potential to degrade tests and accuracy. In remote locations, poor quality diagnostics and drugs may have significant negative health impact that is not readily detectable by routine monitoring. This study assessed temperature and humidity throughout supply chains used to transport and store health commodities, such as RDTs. Monitoring devices capable of recording temperature and humidity were deployed to Burkina Faso (8), Senegal (10), Ethiopia (13) and the Philippines (6) over a 13-month period. The devices travelled through government supply chains, usually alongside RDTs, to health facilities where RDTs are stored, distributed and used. The recording period spanned just over a year, in order to avoid any biases related to seasonal temperature variations. In the four countries, storage and transport temperatures regularly exceeded 30.0°C; maximum humidity level recorded was above 94% for the four countries. In three of the four countries, temperatures recorded at central storage facilities exceeded pharmaceutical storage standards for over 20% of the time, in another case for a majority of the time; and sometimes exceeded storage temperatures at peripheral sites. Malaria RDTs were regularly exposed to temperatures above recommended limits for many commercially-available RDTs and other medical commodities such as drugs, but rarely exceeded the recommended storage limits for particular products in use in these countries. The results underline the need to select RDTs, and other commodities, according to expected field conditions, actively manage the environmental conditions in supply chains in tropical and sub-tropical climates. This would benefit from a re-visit of current global standards on stability of medical commodities based in tropical and sub-tropical climatic zones.

Uncertainties in Life Cycle Greenhouse Gas Emissions from Advanced Biomass Feedstock Logistics Supply Chains in Kansas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cafferty, Kara G.; Searcy, Erin M.; Nguyen, Long

To meet Energy Independence and Security Act (EISA) cellulosic biofuel mandates, the United States will require an annual domestic supply of about 242 million Mg of biomass by 2022. To improve the feedstock logistics of lignocellulosic biofuels and access available biomass resources from areas with varying yields, commodity systems have been proposed and designed to deliver on-spec biomass feedstocks at preprocessing “depots”, which densify and stabilize the biomass prior to long-distance transport and delivery to centralized biorefineries. The harvesting, preprocessing, and logistics (HPL) of biomass commodity supply chains thus could introduce spatially variable environmental impacts into the biofuel life cyclemore » due to needing to harvest, move, and preprocess biomass from multiple distances that have variable spatial density. This study examines the uncertainty in greenhouse gas (GHG) emissions of corn stover logisticsHPL within a bio-ethanol supply chain in the state of Kansas, where sustainable biomass supply varies spatially. Two scenarios were evaluated each having a different number of depots of varying capacity and location within Kansas relative to a central commodity-receiving biorefinery to test GHG emissions uncertainty. Monte Carlo simulation was used to estimate the spatial uncertainty in the HPL gate-to-gate sequence. The results show that the transport of densified biomass introduces the highest variability and contribution to the carbon footprint of the logistics HPL supply chain (0.2-13 g CO 2e/MJ). Moreover, depending upon the biomass availability and its spatial density and surrounding transportation infrastructure (road and rail), logistics HPL processes can increase the variability in life cycle environmental impacts for lignocellulosic biofuels. Within Kansas, life cycle GHG emissions could range from 24 to 41 g CO 2e/MJ depending upon the location, size and number of preprocessing depots constructed. However, this range can be minimized through optimizing the siting of preprocessing depots where ample rail infrastructure exists to supply biomass commodity to a regional biorefinery supply system« less

Uncertainties in Life Cycle Greenhouse Gas Emissions from Advanced Biomass Feedstock Logistics Supply Chains in Kansas

DOE PAGES

Cafferty, Kara G.; Searcy, Erin M.; Nguyen, Long; ...

2014-11-04

To meet Energy Independence and Security Act (EISA) cellulosic biofuel mandates, the United States will require an annual domestic supply of about 242 million Mg of biomass by 2022. To improve the feedstock logistics of lignocellulosic biofuels and access available biomass resources from areas with varying yields, commodity systems have been proposed and designed to deliver on-spec biomass feedstocks at preprocessing “depots”, which densify and stabilize the biomass prior to long-distance transport and delivery to centralized biorefineries. The harvesting, preprocessing, and logistics (HPL) of biomass commodity supply chains thus could introduce spatially variable environmental impacts into the biofuel life cyclemore » due to needing to harvest, move, and preprocess biomass from multiple distances that have variable spatial density. This study examines the uncertainty in greenhouse gas (GHG) emissions of corn stover logisticsHPL within a bio-ethanol supply chain in the state of Kansas, where sustainable biomass supply varies spatially. Two scenarios were evaluated each having a different number of depots of varying capacity and location within Kansas relative to a central commodity-receiving biorefinery to test GHG emissions uncertainty. Monte Carlo simulation was used to estimate the spatial uncertainty in the HPL gate-to-gate sequence. The results show that the transport of densified biomass introduces the highest variability and contribution to the carbon footprint of the logistics HPL supply chain (0.2-13 g CO 2e/MJ). Moreover, depending upon the biomass availability and its spatial density and surrounding transportation infrastructure (road and rail), logistics HPL processes can increase the variability in life cycle environmental impacts for lignocellulosic biofuels. Within Kansas, life cycle GHG emissions could range from 24 to 41 g CO 2e/MJ depending upon the location, size and number of preprocessing depots constructed. However, this range can be minimized through optimizing the siting of preprocessing depots where ample rail infrastructure exists to supply biomass commodity to a regional biorefinery supply system« less

Living at the edge of an interface area in Zimbabwe: cattle owners, commodity chain and health workers' awareness, perceptions and practices on zoonoses.

PubMed

Gadaga, B M; Etter, E M C; Mukamuri, B; Makwangudze, K J; Pfukenyi, D M; Matope, G

2016-01-28

In the great Limpopo transfrontier conservation area (GLTFCA), there is an increased interface between wildlife and domestic animals, because rural households move their cattle into the game park in search of grazing and watering resources. This creates opportunities for inter-species transmission of infectious diseases, including zoonoses like brucellosis and tuberculosis, which may also pose a health risk to the local rural communities. This study investigated the awareness, perceptions and practices on zoonoses amongst rural cattle owners, commodity chain- and health-workers in three different localities around Gonarezhou National Park (GNP), Zimbabwe, where the interface between wild and domestic animals varies. A cross-sectional study was conducted in Malipati, Chikombedzi and Chiredzi that are considered to be high-, medium- and low-domestic animal-wildlife interface areas, respectively. Data was collected from cattle owners, commodity chain and health-workers using a semi-structured questionnaire. To determine the public health risk of food-borne zoonoses, their practices with regard to meat and milk consumptions, and measures they take to prevent exposure to infections were assessed. Data were analyzed using descriptive statistics and principal component analysis. Most respondents (52.8 %, 102/193) were cattle owners, followed by health (30.1 %, 58/193) and lastly commodity chain workers (17.1 %, 33/193). Overall 67.4 % (130/193) of the respondents were aware of zoonoses with respective 48, 81.8, and 93.1 % of cattle owners, commodity chain, and health workers, being aware. Significantly more cattle owners (P < 0.05) from medium and low interface areas were aware of zoonoses compared to those from high interface areas. All categories of respondents cited anthrax (69.2 %), rabies (57.7 %), tuberculosis (41.5 %) and brucellosis (23.9 %) as important zoonoses. About half (46.1 %; 89/193) of the respondents perceive wildlife as important reservoirs of zoonoses. High proportions 98.4 % (190/193) and 96.4 % (186/193) of the respondents indicated that they consume meat and milk, respectively. Access to game meat and milk from informal markets was closely associated with consumption of raw meat and milk. Fewer cattle owners from a high interface area of Malipati are aware of zoonoses compared to other areas due to combined effects of limited education and other factors disadvantaging these marginalised areas. This may increase their risk of exposure to zoonoses, considering that consumption of raw meat and milk is common. Thus, awareness campaigns may reduce the public health impact of zoonoses at the interface.

Estimates of Embodied Global Energy and Air-Emission Intensities of Japanese Products for Building a Japanese Input–Output Life Cycle Assessment Database with a Global System Boundary

PubMed Central

2012-01-01

To build a life cycle assessment (LCA) database of Japanese products embracing their global supply chains in a manner requiring lower time and labor burdens, this study estimates the intensity of embodied global environmental burden for commodities produced in Japan. The intensity of embodied global environmental burden is a measure of the environmental burden generated globally by unit production of the commodity and can be used as life cycle inventory data in LCA. The calculation employs an input–output LCA method with a global link input–output model that defines a global system boundary grounded in a simplified multiregional input–output framework. As results, the intensities of embodied global environmental burden for 406 Japanese commodities are determined in terms of energy consumption, greenhouse-gas emissions (carbon dioxide, methane, nitrous oxide, perfluorocarbons, hydrofluorocarbons, sulfur hexafluoride, and their summation), and air-pollutant emissions (nitrogen oxide and sulfur oxide). The uncertainties in the intensities of embodied global environmental burden attributable to the simplified structure of the global link input–output model are quantified using Monte Carlo simulation. In addition, by analyzing the structure of the embodied global greenhouse-gas intensities we characterize Japanese commodities in the context of LCA embracing global supply chains. PMID:22881452

Sense and Respond Logistics: Integrating Prediction, Responsiveness, and Control Capabilities

DTIC Science & Technology

2006-01-01

logistics SAR sense and respond SCM Supply Chain Management SCN Supply Chain Network SIDA sense, interpret, decide, act SOS source of supply TCN...commodity supply chain management ( SCM ), will have WS- SCMs that focus on integrating information for a particular MDS. 8 In the remainder of this...developed applications of ABMs for SCM .21 Applications of Agents and Agent-Based Modeling Agents have been used in telecommunications, e-commerce

7 CFR 1291.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM... distribution chain in developing “Good Agricultural Practices”, “Good Handling Practices”, “Good Manufacturing...

7 CFR 1291.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM... distribution chain in developing “Good Agricultural Practices”, “Good Handling Practices”, “Good Manufacturing...

7 CFR 1291.1 - Purpose and scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM... distribution chain in developing “Good Agricultural Practices”, “Good Handling Practices”, “Good Manufacturing...

7 CFR 1291.1 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM... distribution chain in developing “Good Agricultural Practices”, “Good Handling Practices”, “Good Manufacturing...

7 CFR 1291.1 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE SPECIALTY CROP BLOCK GRANT PROGRAM... distribution chain in developing “Good Agricultural Practices”, “Good Handling Practices”, “Good Manufacturing...

Determine the optimal carrier selection for a logistics network based on multi-commodity reliability criterion

NASA Astrophysics Data System (ADS)

Lin, Yi-Kuei; Yeh, Cheng-Ta

2013-05-01

From the perspective of supply chain management, the selected carrier plays an important role in freight delivery. This article proposes a new criterion of multi-commodity reliability and optimises the carrier selection based on such a criterion for logistics networks with routes and nodes, over which multiple commodities are delivered. Carrier selection concerns the selection of exactly one carrier to deliver freight on each route. The capacity of each carrier has several available values associated with a probability distribution, since some of a carrier's capacity may be reserved for various orders. Therefore, the logistics network, given any carrier selection, is a multi-commodity multi-state logistics network. Multi-commodity reliability is defined as a probability that the logistics network can satisfy a customer's demand for various commodities, and is a performance indicator for freight delivery. To solve this problem, this study proposes an optimisation algorithm that integrates genetic algorithm, minimal paths and Recursive Sum of Disjoint Products. A practical example in which multi-sized LCD monitors are delivered from China to Germany is considered to illustrate the solution procedure.

Is women's labor a commodity?

PubMed

Anderson, Elizabeth S

1990-01-01

...A commercial surrogate mother is anyone who is paid money to bear a child for other people and terminate her parental rights, so that the others may raise the child as exclusively their own. The growth of commercial surrogacy has raised with new urgency a class of concerns regarding the proper scope of the market. Some critics have objected to commercial surrogacy on the ground that it improperly treats children and women's reproductive capacities as commodities. The prospect of reducing children to consumer durables and women to baby factories surely inspires revulsion. But are there good reasons behind the revulsion? And is this an accurate description of what commercial surrogacy implies? This article offers a theory about what things are properly regarded as commodities which supports the claim that commercial surrogacy constitutes an unconscionable commodification of children and of women's reproductive capacities.

Norwegian Salmon Goes to Market: The Case of the Austevoll Seafood Cluster

ERIC Educational Resources Information Center

Phyne, John; Hovgaard, Gestur; Hansen, Gard

2006-01-01

This paper examines the impact of the globalisation of the farmed salmon commodity chain upon farmed salmon production in the western Norwegian municipality of Austevoll. On the basis of field research conducted in 2002 and 2003, we conclude that salmon farming in Austevoll has responded to the challenges of "buyer-driven" food chains by…

17 CFR 4.5 - Exclusion for certain otherwise regulated persons from the definition of the term “commodity pool...

Code of Federal Regulations, 2012 CFR

2012-04-01

... retail forex transaction, by calculating the value in U.S. Dollars for such transaction, at the time the... such retail forex transaction, by calculating the value in U.S. Dollars for such transaction, at the...

17 CFR 248.102 - Examples.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Examples. 248.102 Section 248... AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The examples in this subpart are not exclusive. The examples in this subpart provide guidance concerning the rules' application...

17 CFR 210.3A-02 - Consolidated financial statements of the registrant and its subsidiaries.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 1975 Consolidated and Combined Financial Statements § 210.3A-02 Consolidated financial statements of... consolidated financial statements principles of inclusion or exclusion which will clearly exhibit the financial... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Consolidated financial...

75 FR 75727 - Implementing the Whistleblower Provisions of Section 23 of the Commodity Exchange Act

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-06

... corporate filings, media, and the Internet. Importantly, the proposed definition of ``independent knowledge..., or communications (subject to the exclusion for knowledge obtained from public sources). Thus, for... that was obtained through a communication that is subject to the attorney-client privilege. (Proposed...

HIV/AIDS related commodities supply chain management in public health facilities of Addis Ababa, Ethiopia: a cross-sectional survey.

PubMed

Berhanemeskel, Eyerusalem; Beedemariam, Gebremedhin; Fenta, Teferi Gedif

2016-01-01

A wide range of pharmaceutical products are needed for diagnosis, treatment, and prevention of HIV/AIDS. However, interrupted supplies and stock-outs are the major challenges in the supply chain of ARV medicines and related commodities. The aim of this study was to assess the supply chain management of HIV/AIDS related commodities in public health facilities of Addis Ababa, Ethiopia. A descriptive cross-sectional survey complemented by qualitative method was conducted in 24 public health facilities (4 hospitals and 20 health centers). A semi-structured questionnaire and observation check list were used to collect data on HIV/AIDS related service, reporting and ordering; receiving, transportation and storage condition of ARV medicines and test kits; and supportive supervision and logistics management information system. In addition, in-depth interview with flexible probing techniques was used to complement the quantitative data with emphasis to the storage condition of ARV medicines and test kits. Quantitative data was analyzed using SPSS version-20. Analysis of qualitative data involved rigorous reading of transcripts in order to identify key themes and data was analyzed using thematic approach. The study revealed that 16 health centers and one hospital had recorded and reported patient medication record. Six months prior to the study, 14 health centers and 2 hospitals had stopped VCT services for one time or more. Three hospitals and 18 health centers claimed to have been able to submit the requisition and report concerning ARV medicines to Pharmaceutical Fund and Supply Agency according to the specific reporting period. More than three-fourth of the health centers had one or more emergency order of ARV medicines on the day of visit, while all of hospitals had emergency order more than 3 times within 6 months prior to the study. All of the hospitals and nearly half of the health centers had an emergency order of test kits more than 3 times in the past 6 months. Overall, nearly 3/4th of the health facilities faced stock-out of one or more ARV medicines and test kits on the day of visit. There was no adequate data on patient medication record and stock status of HIV/AIDS related commodities. Moreover there were frequent stock-outs of ARV medicines and HIV test kits, which was an indicator of the weak supply chain management. Hospitals and health centers, therefore, should devise a system to capture and make use of patient medication record and stock status information so as to ensure continuous supply of the commodities.

48 CFR 225.7001 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Mooring Chain. (c) “End product” is defined in the clause at 252.225-7012, Preference for Certain Domestic Commodities. (d) Hand or measuring tools means those tools listed in Federal supply classifications 51 and 52...

48 CFR 225.7001 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Mooring Chain. (c) “End product” is defined in the clause at 252.225-7012, Preference for Certain Domestic Commodities. (d) Hand or measuring tools means those tools listed in Federal supply classifications 51 and 52...

48 CFR 225.7001 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Mooring Chain. (c) “End product” is defined in the clause at 252.225-7012, Preference for Certain Domestic Commodities. (d) Hand or measuring tools means those tools listed in Federal supply classifications 51 and 52...

48 CFR 225.7001 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Mooring Chain. (c) “End product” is defined in the clause at 252.225-7012, Preference for Certain Domestic Commodities. (d) Hand or measuring tools means those tools listed in Federal supply classifications 51 and 52...

48 CFR 225.7001 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Mooring Chain. (c) “End product” is defined in the clause at 252.225-7012, Preference for Certain Domestic Commodities. (d) Hand or measuring tools means those tools listed in Federal supply classifications 51 and 52...

15 CFR Appendix C to Part 30 - Summary of Exemptions and Exclusions From EEI Filing

Code of Federal Regulations, 2013 CFR

2013-01-01

... in races or contests; and animals imported for breeding or exhibition and imported for use by... quantities of commodities and software intended for use by individual USPPIs or by employees or..., medicinal and surgical supplies, food stores, slop chest articles, and saloon stores or supplies for use or...

Conceptual Model of Supply Chain Structure Mapping - A Case of Subsidized LPG Commodity in Yogyakarta

NASA Astrophysics Data System (ADS)

Sulistio, Joko; Thoif, Afifuddin; Fitri Alindira, Aulia

2016-01-01

— In 2007, the government launched a conversion program of kerosene to LPG by issuing a Presidential Regulation No. 104/2007 on Supply, Distribution and Pricing LPG 3 Kg. Article 2 on the regulation says that setting the supply, distribution, and pricing of LPG 3 Kg include planning an annual sales volume of enterprises, the reference price and the retail price and conditions of export and import of LPG 3 Kg in order to reduce subsidies Kerosene especially to divert the use of kerosene according to government policy. In principle, the purpose of this policy is to reduce energy subsidies on commodities, especially Kerosene. Although the government claimed the conversion program is success, there are few problems arising from conversion program. In 2014, many scarcity and high price of LPG 3 Kg were reported. In this case, Pertamina was given full authority to manage all supply chain and distribution. Because the root of the problem of scarcity that occurred in the supply chain system has not been explained, the proposed solutions will also be partial and not comprehensive. Thus, this research will build a structural map of the causes of supply chain system LPG 3 Kg, as well as providing a comprehensive picture of system dynamics of LPG 3 Kg supply chain system which applied in Indonesia. And the result is expected as in form of Causal Loop Diagram of supply chain system.

Managing challenges of import safety in a global market.

DOT National Transportation Integrated Search

2012-06-01

This collaborative will examine market, regulatory, and hybrid approaches to managing risk from deliberate or unintentional contamination in : imported commodity products from the global supply chain, through research and on-campus activities involvi...

78 FR 62787 - Self-Regulatory Organizations; Chicago Mercantile Exchange Inc.; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... component of its current IRS margin model. The proposed change is reflected in an Advisory Notice issued to... offers clearing for a variety of swaps products under the exclusive jurisdiction of the Commodity Futures... rate swaps (``IRS''). CME proposes to make certain changes to its current IRS margin model in relation...

17 CFR 230.168 - Exemption from sections 2(a)(10) and 5(c) of the Act for certain communications of regularly...

Code of Federal Regulations, 2011 CFR

2011-04-01

... and forward-looking information. 230.168 Section 230.168 Commodity and Securities Exchanges SECURITIES... factual business information and forward-looking information. Preliminary Notes to § 230.168. 1. This... provides a non-exclusive safe harbor for factual business information and forward-looking information...

Microbial synthesis of medium-chain chemicals from renewables.

PubMed

Sarria, Stephen; Kruyer, Nicholas S; Peralta-Yahya, Pamela

2017-12-01

Linear, medium-chain (C8-C12) hydrocarbons are important components of fuels as well as commodity and specialty chemicals. As industrial microbes do not contain pathways to produce medium-chain chemicals, approaches such as overexpression of endogenous enzymes or deletion of competing pathways are not available to the metabolic engineer; instead, fatty acid synthesis and reversed β-oxidation are manipulated to synthesize medium-chain chemical precursors. Even so, chain lengths remain difficult to control, which means that purification must be used to obtain the desired products, titers of which are typically low and rarely exceed milligrams per liter. By engineering the substrate specificity and activity of the pathway enzymes that generate the fatty acyl intermediates and chain-tailoring enzymes, researchers can boost the type and yield of medium-chain chemicals. Development of technologies to both manipulate chain-tailoring enzymes and to assay for products promises to enable the generation of g/L yields of medium-chain chemicals.

75 FR 38073 - Information Collection; Commodity Request (Food Aid Request Entry System (FARES))

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... related to this activity is collected and processed electronically through the FARES. The Web-Based Supply Chain Management system (WBSCM) is a new procurement system in development to replace FARES at a later...

Chimeric Fatty Acyl-Acyl Carrier Protein Thioesterases Provide Mechanistic Insight into Enzyme Specificity and Expression.

PubMed

Ziesack, Marika; Rollins, Nathan; Shah, Aashna; Dusel, Brendon; Webster, Gordon; Silver, Pamela A; Way, Jeffrey C

2018-05-15

Medium-chain fatty acids are commodity chemicals. Increasing and modifying the activity of thioesterases (TEs) on medium-chain fatty acyl-acyl carrier protein (acyl-ACP) esters may enable a high-yield microbial production of these molecules. The plant Cuphea palustris harbors two distinct TEs: C. palustris FatB1 ( Cp FatB1) (C 8 specificity, lower activity) and Cp FatB2 (C 14 specificity, higher activity) with 78% sequence identity. We combined structural features from these two enzymes to create several chimeric TEs, some of which showed nonnatural fatty acid production as measured by an enzymatic assay and gas chromatography-mass spectrometry (GC-MS). Notably, chimera 4 exhibited an increased C 8 fatty acid production in correlation with improved microbial expression. This chimera led us to identify Cp FatB2-specific amino acids between positions 219 and 272 that lead to higher protein levels. Chimera 7 produced a broad range of fatty acids and appeared to combine a fatty acid binding pocket with long-chain specificity and an ACP interaction site that may activate fatty acid extrusion. Using homology modeling and in silico docking with ACP, we identified a "positive patch" within amino acids 162 to 218, which may direct the ACP interaction and regulate access to short-chain fatty acids. On the basis of this modeling, we transplanted putative ACP interaction sequences from Cp FatB1 into Cp FatB2 and created a chimeric thioesterase that produced medium-chain as well as long-chain fatty acids. Thus, the engineering of chimeric enzymes and characterizing their microbial activity and chain-length specificity suggested mechanistic insights into TE functions and also generated thioesterases with potentially useful properties. These observations may inform a rational engineering of TEs to allow alkyl chain length control. IMPORTANCE Medium-chain fatty acids are important commodity chemicals. These molecules are used as plastic precursors and in shampoos and other detergents and could be used as biofuel precursors if production economics were favorable. Hydrocarbon-based liquid fuels must be optimized to have a desired boiling point, low freezing point, low viscosity, and other physical characteristics. Similarly, the solubility and harshness of detergents and the flexibility of plastic polymers can be modulated. The length and distribution of the carbon chains in the hydrophobic tails determine these properties. The biological synthesis of cell membranes and fatty acids produces chains of primarily 16 to 18 carbons, which give rise to current biofuels. The ultimate goal of the work presented here is to engineer metabolic pathways to produce designer molecules with the correct number of carbons in a chain, so that such molecules could be used directly as specialty commodity chemicals or as fuels after minimal processing. Copyright © 2018 American Society for Microbiology.

International Trade Modelling Using Open Flow Networks: A Flow-Distance Based Analysis.

PubMed

Shen, Bin; Zhang, Jiang; Li, Yixiao; Zheng, Qiuhua; Li, Xingsen

2015-01-01

This paper models and analyzes international trade flows using open flow networks (OFNs) with the approaches of flow distances, which provide a novel perspective and effective tools for the study of international trade. We discuss the establishment of OFNs of international trade from two coupled viewpoints: the viewpoint of trading commodity flow and that of money flow. Based on the novel model with flow distance approaches, meaningful insights are gained. First, by introducing the concepts of trade trophic levels and niches, countries' roles and positions in the global supply chains (or value-added chains) can be evaluated quantitatively. We find that the distributions of trading "trophic levels" have the similar clustering pattern for different types of commodities, and summarize some regularities between money flow and commodity flow viewpoints. Second, we find that active and competitive countries trade a wide spectrum of products, while inactive and underdeveloped countries trade a limited variety of products. Besides, some abnormal countries import many types of goods, which the vast majority of countries do not need to import. Third, harmonic node centrality is proposed and we find the phenomenon of centrality stratification. All the results illustrate the usefulness of the model of OFNs with its network approaches for investigating international trade flows.

International Trade Modelling Using Open Flow Networks: A Flow-Distance Based Analysis

PubMed Central

Shen, Bin; Zhang, Jiang; Li, Yixiao; Zheng, Qiuhua; Li, Xingsen

2015-01-01

This paper models and analyzes international trade flows using open flow networks (OFNs) with the approaches of flow distances, which provide a novel perspective and effective tools for the study of international trade. We discuss the establishment of OFNs of international trade from two coupled viewpoints: the viewpoint of trading commodity flow and that of money flow. Based on the novel model with flow distance approaches, meaningful insights are gained. First, by introducing the concepts of trade trophic levels and niches, countries’ roles and positions in the global supply chains (or value-added chains) can be evaluated quantitatively. We find that the distributions of trading “trophic levels” have the similar clustering pattern for different types of commodities, and summarize some regularities between money flow and commodity flow viewpoints. Second, we find that active and competitive countries trade a wide spectrum of products, while inactive and underdeveloped countries trade a limited variety of products. Besides, some abnormal countries import many types of goods, which the vast majority of countries do not need to import. Third, harmonic node centrality is proposed and we find the phenomenon of centrality stratification. All the results illustrate the usefulness of the model of OFNs with its network approaches for investigating international trade flows. PMID:26569618

17 CFR 4.5 - Exclusion for certain otherwise regulated persons from the definition of the term “commodity pool...

Code of Federal Regulations, 2010 CFR

2010-04-01

... the Employee Retirement Income Security Act of 1974; (iv) Any employee welfare benefit plan that is... compliance with the provisions of this section, the following persons, and any principal or employee thereof... named fiduciary) or an employer maintaining a pension plan that is subject to title I of the Employee...

The Public Interest in the Globally Sustainable Information Society: The Traditional Knowledge Debate

ERIC Educational Resources Information Center

Zografos, Daphne

2006-01-01

Society increasingly perceives information as an owned commodity. As a consequence, laws born from this conception are removing uses of information from the public domain and placing them in an enclosed domain where they are subject to an owner's exclusive control. It has been argued that this enclosure movement poses a threat to the diversity of…

Mining Review

USGS Publications Warehouse

,

2013-01-01

Trends in other sectors of the domestic economy were similar to those in mineral production and consumption rates (Table 1). After continued decline following the 2008-2009 recession, the construction industry began to show signs of improvement late in 2011 and throughout 2012, with increased production and consumption of cement, construction sand and gravel, crushed stone and gypsum, mineral commodities that are used almost exclusively in construction.

A supply chain model to improve the beef quality distribution using investment analysis: A case study

NASA Astrophysics Data System (ADS)

Lupita, Alessandra; Rangkuti, Sabrina Heriza; Sutopo, Wahyudi; Hisjam, Muh.

2017-11-01

There are significant differences related to the quality and price of the beef commodity in traditional market and modern market in Indonesia. Those are caused by very different treatments of the commodity. The different treatments are in the slaughter lines, the transportation from the abattoir to the outlet, the display system, and the control system. If the problem is not solved by the Government, the gap will result a great loss of the consumer regarding to the quality and sustainability of traditional traders business because of the declining interest in purchasing beef in the traditional markets. This article aims to improve the quality of beef in traditional markets. This study proposed A Supply Chain Model that involves the schemes of investment and government incentive for improving the distribution system. The supply chain model is can be formulated using the Mix Integer Linear Programming (MILP) and solved using the IBM®ILOG®CPLEX software. The results show that the proposed model can be used to determine the priority of programs for improving the quality and sustainability business of traditional beef merchants. By using the models, The Government can make a decision to consider incentives for improving the condition.

Analysis of reduced monoclonal antibodies using size exclusion chromatography coupled with mass spectrometry

NASA Astrophysics Data System (ADS)

Liu, Hongcheng; Gaza-Bulseco, Georgeen; Chumsae, Chris

2009-12-01

Size-exclusion chromatography (SEC) has been widely used to detect antibody aggregates, monomer, and fragments. SEC coupled to mass spectrometry has been reported to measure the molecular weights of antibody; antibody conjugates, and antibody light chain and heavy chain. In this study, separation of antibody light chain and heavy chain by SEC and direct coupling to a mass spectrometer was further studied. It was determined that employing mobile phases containing acetonitrile, trifluoroacetic acid, and formic acid allowed the separation of antibody light chain and heavy chain after reduction by SEC. In addition, this mobile phase allowed the coupling of SEC to a mass spectrometer to obtain a direct molecular weight measurement. The application of the SEC-MS method was demonstrated by the separation of the light chain and the heavy chain of multiple recombinant monoclonal antibodies. In addition, separation of a thioether linked light chain and heavy chain from the free light chain and the free heavy chain of a recombinant monoclonal antibody after reduction was also achieved. This optimized method provided a separation of antibody light chain and heavy chain based on size and allowed a direct measurement of molecular weights by mass spectrometry. In addition, this method may help to identify peaks eluting from SEC column directly.

κ chain monoallelic demethylation and the establishment of allelic exclusion

PubMed Central

Mostoslavsky, Raul; Singh, Nandita; Kirillov, Andrei; Pelanda, Roberta; Cedar, Howard; Chess, Andrew; Bergman, Yehudit

1998-01-01

Allelic exclusion in κ light-chain synthesis is thought to result from a feedback mechanism by which the expression of a functional κ light chain on the surface of the B cell leads to an intracellular signal that down-regulates the V(D)J recombinase, thus precluding rearrangement of the other allele. Whereas such a feedback mechanism clearly plays a role in the maintenance of allelic exclusion, here we provide evidence suggesting that the initial establishment of allelic exclusion involves differential availability of the two κ alleles for rearrangement. Analysis of κ+ B-cell populations and of individual κ+ B cells that have rearranged only one allele demonstrates that in these cells, critical sites on the rearranged allele are unmethylated, whereas the nonrearranged allele remains methylated. This pattern is apparently generated by demethylation that is initiated at the small pre-B cell stage, on a single allele, in a process that occurs prior to rearrangement and requires the presence in cis of both the intronic and 3′ κ enhancers. Taken together with data demonstrating that undermethylation is required for rearrangement, these results indicate that demethylation may actually underly the process of allelic exclusion by directing the initial choice of a single κ allele for rearrangement. PMID:9637682

Targeting mycotoxin biosynthesis pathway genes

USDA-ARS?s Scientific Manuscript database

Chemical detoxification and physical destruction of aflatoxins in foods and feed commodities is mostly unattainable in a way that preserves the edibility of the food. Therefore, preventing mycotoxins in general and aflatoxins in particular from entering the food chain is a better approach. This requ...

Species protection, the changing informal economy, and the politics of access to the bushmeat trade in the Democratic Republic of Congo.

PubMed

De Merode, Emmanuel; Cowlishaw, Guy

2006-08-01

Our understanding of the linkages between the bushmeat trade and the wider informal economy is limited. This lack of knowledge is particularly problematic for conservation under conditions of political instability, when the informal economy can be highly dynamic and impacts on wildlife populations can be severe. To explore these interlinked processes, we conducted a study of the bushmeat trade in Garamba National Park, Democratic Republic of Congo, through a combination of market surveys, semistructured interviews, and direct observation. We focused on the sale of protected and unprotected species in urban and rural markets, and the bushmeat commodity chains that supplied these markets, under conditions of political stability and armed conflict. During peacetime, protected species from the park (predominantly elephant and buffalo) rarely appeared in the rural markets, but they comprised more than half of all bushmeat sales in the urban markets. This pattern reflected differences in the rural and urban commodity chains. Automatic weapons were urban trade. The use of such weapons was discouraged by the traditional chiefs, who administered the village markets. During wartime, the sales of protected species in the urban markets increased fivefold because the military officers fled, leaving behind an open-access system that led to a massive increase in the exploitation of protected species. In contrast, the rural markets remained relatively stable because of the continued authority of the village chiefs. Our results indicate that sociopolitical factors can be an important determinant of species offtake and, therefore, that knowledge of the bushmeat commodity chain can be vital to controlling theprocesses that drive species extraction. In addition, our findings suggest that traditional authorities can be potentially valuable partners for bushmeat management.

Capture, Movement, Trade, and Consumption of Mammals in Madagascar

PubMed Central

Reuter, Kim E.; Randell, Haley; Wills, Abigail R.; Janvier, Totozafy Eric; Belalahy, Tertius Rodriguez; Sewall, Brent J.

2016-01-01

Wild meat trade constitutes a threat to many animal species. Understanding the commodity chain of wild animals (hunting, transportation, trade, consumption) can help target conservation initiatives. Wild meat commodity chain research has focused on the formal trade and less on informal enterprises, although informal enterprises contribute to a large portion of the wild meat trade in sub-Saharan Africa. We aimed to provide a more comprehensive understanding of the formal and informal components of these commodity chains by focusing on the mammalian wild meat trade in Madagascar. Our objectives were to: (1) identify hunting strategies used to capture different wild mammals; (2) analyze patterns of movement of wild meat from the capture location to the final consumer; (3) examine wild meat prices, volumes, and venues of sale; and (4) estimate the volume of wild meat consumption. Data were collected in May-August 2013 using semi-structured interviews with consumers (n = 1343 households, 21 towns), meat-sellers (n = 520 restaurants, open-air markets stalls, and supermarkets, 9 towns), and drivers of inter-city transit vehicles (n = 61, 5 towns). We found that: (1) a wide range of hunting methods were used, though prevalence of use differed by animal group; (2) wild meat was transported distances of up to 166 km to consumers, though some animal groups were hunted locally (<10 km) in rural areas; (3) most wild meat was procured from free sources (hunting, gifts), though urban respondents who consumed bats and wild pigs were more likely to purchase those meats; and (4) wild meat was consumed at lower rates than domestic meat, though urban respondents consumed wild meat twice as much per year compared to rural respondents. Apart from the hunting stage, the consumption and trade of wild meat in Madagascar is also likely more formalized than previously thought. PMID:26926987

What are we missing? Scope 3 greenhouse gas emissions accounting in the metals and minerals industry

NASA Astrophysics Data System (ADS)

Greene, Suzanne E.

2018-05-01

Metal and mineral companies have significant greenhouse gas emissions in their upstream and downstream value chains due to outsourced extraction, beneficiation and transportation activities, depending on a firm's business model. While many companies move towards more transparent reporting of corporate greenhouse gas emissions, value chain emissions remain difficult to capture, particularly in the global supply chain. Incomplete reports make it difficult for companies to track emissions reductions goals or implement sustainable supply chain improvements, especially for commodity products that form the base of many other sector's value chains. Using voluntarily-reported CDP data, this paper sheds light on hotspots in value chain emissions for individual metal and mineral companies, and for the sector as a whole. The state of value chain emissions reporting for the industry is discussed in general, with a focus on where emissions could potentially be underestimated and how estimates could be improved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Amy Cha-Tien; Downes, Paula Sue; Heinen, Russell

Analysis of chemical supply chains is an inherently complex task, given the dependence of these supply chains on multiple infrastructure systems (e.g., the petroleum sector, transportation, etc.). This effort requires data and information at various levels of resolution, ranging from network-level distribution systems to individual chemical reactions. Sandia National Laboratories (Sandia) has integrated its existing simulation and infrastructure analysis capabilities with chemical data models to analyze the chemical supply chains of several nationally critical chemical commodities. This paper describes how Sandia models the ethylene supply chain; that is, the supply chain for the most widely used raw material for plasticsmore » production including a description of the types of data and modeling capabilities that are required to represent the ethylene supply chain. The paper concludes with a description of Sandia's use the model to project how the supply chain would be affected by and adapt to a disruptive scenario hurricane.« less

Forest Conversion, Agricultural Transitions and the Influence of Multi-scale Market Factors in Southwest Cameroon

NASA Astrophysics Data System (ADS)

Ordway, E.; Lambin, E.; Asner, G. P.

2015-12-01

The changing structure of demand for commodities associated with food security and energy has had a startling impact on land use change in tropical forests in recent decades. Yet, the composition of conversion in the Congo basin remains a major uncertainty, particularly with regards to the scale of drivers of change. Owing to rapid expansion of production globally and longstanding historical production locally in the Congo basin, oil palm offers a lens through which to evaluate local land use decisions across a spectrum of small- to large-scales of production as well as interactions with regional and global supply chains. We examined the effect of global commodity crop expansion on land use change in Southwest Cameroon using a mixed-methods approach to integrate remote sensing, field surveys and socioeconomic data. Southwest Cameroon (2.5 Mha) has a long history of large- and small-scale agriculture, ranging from mixed crop subsistence agriculture to large monocrop plantations of oil palm, cocoa, and rubber. Trends and spatial patterns of forest conversion and agricultural transitions were analyzed from 2000-2015 using satellite imagery. We used economic, demographic and field survey datasets to assess how regional and global market factors and local commodity crop decisions affect land use patterns. Our results show that oil palm is a major commodity crop expanding in this region, and that conversion is occurring primarily through expansion by medium-scale producers and local elites. Results also indicate that global and regional supply chain dynamics influence local land use decision making. This research contributes new information on land use patterns and dynamics in the Congo basin, an understudied region. More specifically, results from this research contribute information on recent trends of oil palm expansion in Cameroon that will be used in national land use planning strategies.

The dynamic simulation model of soybean in Central Java to support food self sufficiency: A supply chain perspective

NASA Astrophysics Data System (ADS)

Oktyajati, Nancy; Hisjam, Muh.; Sutopo, Wahyudi

2018-02-01

Consider food become one of the basic human needs in order to survive so food sufficiency become very important. Food sufficiency of soybean commodity in Central Java still depends on imported soybean. Insufficiency of soybean because of there is much gap between local soybean productions and its demand. In the year 2016 the shortage of supply soybean commodity as much 68.79%. Soybean is an important and strategic commodity after rice and corn. The increasing consumption of soybean is related to increasing population, increasing incomes, changing of healthy life style. The aims of this study are to determine the soybean dynamic model based on supply chain perspective, define the proper price of local soybean to trigger increasing of local production, and to define the alternative solution to support food self sufficiency. This study will capture the real condition into dynamics model, then simulate a series of scenario into a computer program to obtain the best results. This study will be conducted the following first scenario with government intervention policy and second without government intervention policy. The best solution of the alternative can be used as government consideration for governmental policy. The results of the propose scenarios showed that self sufficiency on soybean can be achieved after the next 20 years by increasing planting area 4% and land productivity 1% per year.

Evaluation of chlorpyrifos transferred from contaminated feed to duck commodities and dietary risks to Chinese consumers.

PubMed

Li, Rui; Ji, Xiaofeng; He, Liang; Liu, Zhiqiang; Wei, Wei; Qiang, Mingrong; Wang, Qiang; Yuan, Yuwei

2015-06-03

The present study describes chlorpyrifos residues in duck commodities through the duck food chain, transfer factors, and dietary risks to Chinese consumers. After duck feeding experiments with pellet feed that lasted for 42 days, chlorpyrifos residues found in all samples collected from the ducks on maximum estimated dose group (3.20 mg/kg level) were from <0.0005 to 0.019 mg/kg. The residue levels of the fat, intestine, and tongue were obviously higher than those of the meat and other edible tissues. The transfer factors of all duck commodities were from 0.0001 to 0.0049 among different contamination levels, which indicated that chlorpyrifos had a low persistency in duck meat and metabolism organs. The chronic exposure assessment revealed that only 0.034-0.150% of the acceptable daily intake (ADI; 0-0.01 mg/kg/bw/day) of chlorpyrifos was consumed via the duck commodities for different age and gender groups in China. The acute exposure assessments of different age and gender groups were only 0.019-0.082% of the acute reference dose (ARfD; 0-0.1 mg/kg/bw). The results show that the single dietary exposure risk of chlorpyrifos raised by the intake of duck commodities was quite low in China.

Whole genome sequence analysis of unidentified genetically modified papaya for development of a specific detection method.

PubMed

Nakamura, Kosuke; Kondo, Kazunari; Akiyama, Hiroshi; Ishigaki, Takumi; Noguchi, Akio; Katsumata, Hiroshi; Takasaki, Kazuto; Futo, Satoshi; Sakata, Kozue; Fukuda, Nozomi; Mano, Junichi; Kitta, Kazumi; Tanaka, Hidenori; Akashi, Ryo; Nishimaki-Mogami, Tomoko

2016-08-15

Identification of transgenic sequences in an unknown genetically modified (GM) papaya (Carica papaya L.) by whole genome sequence analysis was demonstrated. Whole genome sequence data were generated for a GM-positive fresh papaya fruit commodity detected in monitoring using real-time polymerase chain reaction (PCR). The sequences obtained were mapped against an open database for papaya genome sequence. Transgenic construct- and event-specific sequences were identified as a GM papaya developed to resist infection from a Papaya ringspot virus. Based on the transgenic sequences, a specific real-time PCR detection method for GM papaya applicable to various food commodities was developed. Whole genome sequence analysis enabled identifying unknown transgenic construct- and event-specific sequences in GM papaya and development of a reliable method for detecting them in papaya food commodities. Copyright © 2016 Elsevier Ltd. All rights reserved.

Air Force Commodity Councils: A Template for Future Implementation Comparing Successful and Failed Approaches

DTIC Science & Technology

2007-12-01

Northwest QantasLink 67 References Mankiw , N. Gregory, Essentials of Economics , Chapter 13 Weinstein, David E; Yafeh...Purchasing, Transaction Cost Analysis, Transaction Cost Economics , Air Force, Supply Chain Management, Procurement, Transformation 16. PRICE CODE 17...SOURCING .............................................................................7 C. TRANSACTION COST ECONOMICS

An exploration in mineral supply chain mapping using tantalum as an example

USGS Publications Warehouse

Soto-Viruet, Yadira; Menzie, W. David; Papp, John F.; Yager, Thomas R.

2013-01-01

This report uses the supply chain of tantalum (Ta) to investigate the complexity of mineral and metal supply chains in general and show how they can be mapped. A supply chain is made up of all the manufacturers, suppliers, information networks, and so forth, that provide the materials and parts that go into making up a final product. The mineral portion of the supply chain begins with mineral material in the ground (the ore deposit); extends through a series of processes that include mining, beneficiation, processing (smelting and refining), semimanufacture, and manufacture; and continues through transformation of the mineral ore into concentrates, refined mineral commodities, intermediate forms (such as metals and alloys), component parts, and, finally, complex products. This study analyses the supply chain of tantalum beginning with minerals in the ground to many of the final goods that contain tantalum.

Developing sustainable food supply chains.

PubMed

Smith, B Gail

2008-02-27

This paper reviews the opportunities available for food businesses to encourage consumers to eat healthier and more nutritious diets, to invest in more sustainable manufacturing and distribution systems and to develop procurement systems based on more sustainable forms of agriculture. The important factors in developing more sustainable supply chains are identified as the type of supply chain involved and the individual business attitude to extending responsibility for product quality into social and environmental performance within their own supply chains. Interpersonal trust and working to standards are both important to build more sustainable local and many conserved food supply chains, but inadequate to transform mainstream agriculture and raw material supplies to the manufactured and commodity food markets. Cooperation among food manufacturers, retailers, NGOs, governmental and farmers' organizations is vital in order to raise standards for some supply chains and to enable farmers to adopt more sustainable agricultural practices.

46 CFR 69.119 - Spaces deducted from gross tonnage.

Code of Federal Regulations, 2011 CFR

2011-10-01

... gear, capstan, windlass, and chain locker is deductible. A fore peak used exclusively as chain locker... oils, blocks, hawsers, rigging, deck gear, or other boatswain's stores for daily use is deductible. The...

46 CFR 69.119 - Spaces deducted from gross tonnage.

Code of Federal Regulations, 2013 CFR

2013-10-01

... gear, capstan, windlass, and chain locker is deductible. A fore peak used exclusively as chain locker... oils, blocks, hawsers, rigging, deck gear, or other boatswain's stores for daily use is deductible. The...

46 CFR 69.119 - Spaces deducted from gross tonnage.

Code of Federal Regulations, 2012 CFR

2012-10-01

... gear, capstan, windlass, and chain locker is deductible. A fore peak used exclusively as chain locker... oils, blocks, hawsers, rigging, deck gear, or other boatswain's stores for daily use is deductible. The...

46 CFR 69.119 - Spaces deducted from gross tonnage.

Code of Federal Regulations, 2010 CFR

2010-10-01

... gear, capstan, windlass, and chain locker is deductible. A fore peak used exclusively as chain locker... oils, blocks, hawsers, rigging, deck gear, or other boatswain's stores for daily use is deductible. The...

Branched-chain fatty acid methyl esters as cold flow improvers for biodiesel

USDA-ARS?s Scientific Manuscript database

Biodiesel is an alternative diesel fuel derived mainly from the transesterification of plant oils with methanol or ethanol. This fuel is generally made from commodity oils such as canola, palm, or soybean and has a number of properties that make it compatible in compression-ignition engines. Despite...

Integration of vaccine supply chains with other health commodity supply chains: a framework for decision making.

PubMed

Yadav, Prashant; Lydon, Patrick; Oswald, Julianna; Dicko, Modibo; Zaffran, Michel

2014-11-28

One of the primary objectives of National Immunization Programs is to strengthen and optimize immunization supply chains so that vaccines are delivered to the end recipients effectively, efficiently and sustainably. As a result of larger investments in global health and a wider portfolio of vaccines, global agencies are recognizing the need for vaccine supply chains to operate at their most optimal levels. Integration with other supply chains is often presented as a strategy to improve efficiency. However, it remains unclear if the proposed benefits from integration of vaccine supply chains with other supply chains will outweigh the costs. This paper provides a framework for deciding where such integration offers the most significant benefits. It also cautions about the pitfalls of integration as a one size fits all strategy. It also highlights the need for systematic collection of cost and efficiency data in order to understand the value of integration and other such initiatives. Copyright © 2014 Elsevier Ltd. All rights reserved.

Assessment of laboratory logistics management information system practice for HIV/AIDS and tuberculosis laboratory commodities in selected public health facilities in Addis Ababa, Ethiopia.

PubMed

Desale, Adino; Taye, Bineyam; Belay, Getachew; Nigatu, Alemayehu

2013-01-01

Logistics management information system for health commodities remained poorly implemented in most of developing countries. To assess the status of laboratory logistics management information system for HIV/AIDS and tuberculosis laboratory commodities in public health facilities in Addis Ababa. A cross-sectional descriptive study was conducted from September 2010-January 2011 at selected public health facilities. A stratified random sampling method was used to include a total of 43 facilities which, were investigated through quantitative methods using structured questionnaires interviews. Focus group discussion with the designated supply chain managers and key informant interviews were conducted for the qualitative method. There exists a well-designed logistics system for laboratory commodities with trained pharmacy personnel, distributed standard LMIS formats and established inventory control procedures. However, majority of laboratory professionals were not trained in LMIS. Majority of the facilities (60.5%) were stocked out for at least one ART monitoring and TB laboratory reagents and the highest stock out rate was for chemistry reagents. Expired ART monitoring laboratory commodities were found in 25 (73.5%) of facilities. Fifty percent (50%) of the assessed hospitals and 54% of health centers were currently using stock/bin cards for all HIV/AIDS and TB laboratory commodities in main pharmacy store, among these only 25% and 20.8% of them were updated with accurate information matching with the physical count done at the time of visit for hospitals and health centers respectively. Even though there exists a well designed laboratory LMIS, keeping quality stock/bin cards and LMIS reports were very low. Key ART monitoring laboratory commodities were stock out at many facilities at the day of visit and during the past six months. Based on findings, training of laboratory personnel's managing laboratory commodities and keeping accurate inventory control procedures were recommended.

Assessment of laboratory logistics management information system practice for HIV/AIDS and tuberculosis laboratory commodities in selected public health facilities in Addis Ababa, Ethiopia

PubMed Central

Desale, Adino; Taye, Bineyam; Belay, Getachew; Nigatu, Alemayehu

2013-01-01

Introduction Logistics management information system for health commodities remained poorly implemented in most of developing countries. To assess the status of laboratory logistics management information system for HIV/AIDS and tuberculosis laboratory commodities in public health facilities in Addis Ababa. Methods A cross-sectional descriptive study was conducted from September 2010-January 2011 at selected public health facilities. A stratified random sampling method was used to include a total of 43 facilities which, were investigated through quantitative methods using structured questionnaires interviews. Focus group discussion with the designated supply chain managers and key informant interviews were conducted for the qualitative method. Results There exists a well-designed logistics system for laboratory commodities with trained pharmacy personnel, distributed standard LMIS formats and established inventory control procedures. However, majority of laboratory professionals were not trained in LMIS. Majority of the facilities (60.5%) were stocked out for at least one ART monitoring and TB laboratory reagents and the highest stock out rate was for chemistry reagents. Expired ART monitoring laboratory commodities were found in 25 (73.5%) of facilities. Fifty percent (50%) of the assessed hospitals and 54% of health centers were currently using stock/bin cards for all HIV/AIDS and TB laboratory commodities in main pharmacy store, among these only 25% and 20.8% of them were updated with accurate information matching with the physical count done at the time of visit for hospitals and health centers respectively. Conclusion Even though there exists a well designed laboratory LMIS, keeping quality stock/bin cards and LMIS reports were very low. Key ART monitoring laboratory commodities were stock out at many facilities at the day of visit and during the past six months. Based on findings, training of laboratory personnel's managing laboratory commodities and keeping accurate inventory control procedures were recommended. PMID:24106574

Price competition and equilibrium analysis in multiple hybrid channel supply chain

NASA Astrophysics Data System (ADS)

Kuang, Guihua; Wang, Aihu; Sha, Jin

2017-06-01

The amazing boom of Internet and logistics industry prompts more and more enterprises to sell commodity through multiple channels. Such market conditions make the participants of multiple hybrid channel supply chain compete each other in traditional and direct channel at the same time. This paper builds a two-echelon supply chain model with a single manufacturer and a single retailer who both can choose different channel or channel combination for their own sales, then, discusses the price competition and calculates the equilibrium price under different sales channel selection combinations. Our analysis shows that no matter the manufacturer and retailer choose same or different channel price to compete, the equilibrium price does not necessarily exist the equilibrium price in the multiple hybrid channel supply chain and wholesale price change is not always able to coordinate supply chain completely. We also present the sufficient and necessary conditions for the existence of equilibrium price and coordination wholesale price.

Chemical variability along the value chains of turmeric (Curcuma longa): a comparison of nuclear magnetic resonance spectroscopy and high performance thin layer chromatography.

PubMed

Booker, Anthony; Frommenwiler, Debora; Johnston, Deborah; Umealajekwu, Chinenye; Reich, Eike; Heinrich, Michael

2014-03-14

Herbal medicine value chains have generally been overlooked compared with food commodities. Not surprisingly, revenue generation tends to be weighted towards the end of the chain and consequently the farmers and producers are the lowest paid beneficiaries. Value chains have an impact both on the livelihood of producers and on the composition and quality of products commonly sold locally and globally and consequently on the consumers. In order to understand the impact of value chains on the composition of products, we studied the production conditions for turmeric (Curcuma longa) and the metabolomic composition of products derived from it. We aimed at integrating these two components in order to gain a better understanding of the effect of different value chains on the livelihoods of some producers. This interdisciplinary project uses a mixed methods approach. Case studies were undertaken on two separate sites in India. Data was initially gathered on herbal medicine value chains by means of semi-structured interviews and non-participant observations. Samples were collected from locations in India, Europe and the USA and analysed using (1)H NMR spectroscopy coupled with multivariate analysis software and with high performance thin layer chromatography (HPTLC). We investigate medicinal plant value chains and interpret the impact different value chains have on some aspects of the livelihoods of producers in India and, for the first time, analytically assess the chemical variability and quality implications that different value chains may have on the products available to end users in Europe. There are benefits to farmers that belonged to an integrated chain and the resulting products were subject to a higher standard of processing and storage. By using analytical methods, including HPTLC and (1)H NMR spectroscopy, it has been possible to correlate some variations in product composition for selected producers and identify strengths and weaknesses of some types of value chains. The two analytical techniques provide different and complementary data and together they can be used to effectively differentiate between a wide variety of crude drug powders and herbal medicinal products. This project demonstrates that there is a need to study the links between producers and consumers of commodities produced in so-called 'provider countries' and that metabolomics offer a novel way of assessing the chemical variability along a value chain. This also has implications for understanding the impact this has on the livelihood of those along the value chain. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

27 CFR 53.100 - Exclusion of local advertising charges from sale price.

Code of Federal Regulations, 2014 CFR

2014-04-01

... section, the advertising must be initiated or obtained by one or more of the persons in the chain of... chain of distribution of the article. In general, advertising of an article is considered to be initiated or obtained by one or more persons in the chain of distribution of the article if any such person...

27 CFR 53.100 - Exclusion of local advertising charges from sale price.

Code of Federal Regulations, 2013 CFR

2013-04-01

... section, the advertising must be initiated or obtained by one or more of the persons in the chain of... chain of distribution of the article. In general, advertising of an article is considered to be initiated or obtained by one or more persons in the chain of distribution of the article if any such person...

27 CFR 53.100 - Exclusion of local advertising charges from sale price.

Code of Federal Regulations, 2012 CFR

2012-04-01

... section, the advertising must be initiated or obtained by one or more of the persons in the chain of... chain of distribution of the article. In general, advertising of an article is considered to be initiated or obtained by one or more persons in the chain of distribution of the article if any such person...

27 CFR 53.100 - Exclusion of local advertising charges from sale price.

Code of Federal Regulations, 2010 CFR

2010-04-01

... section, the advertising must be initiated or obtained by one or more of the persons in the chain of... chain of distribution of the article. In general, advertising of an article is considered to be initiated or obtained by one or more persons in the chain of distribution of the article if any such person...

27 CFR 53.100 - Exclusion of local advertising charges from sale price.

Code of Federal Regulations, 2011 CFR

2011-04-01

... section, the advertising must be initiated or obtained by one or more of the persons in the chain of... chain of distribution of the article. In general, advertising of an article is considered to be initiated or obtained by one or more persons in the chain of distribution of the article if any such person...

26 CFR 1.959-1 - Exclusion from gross income of United States persons of previously taxed earnings and profits.

Code of Federal Regulations, 2010 CFR

2010-04-01

... amounts so taxed are taxed again when actually distributed directly, or indirectly through a chain of... chain of ownership where such amounts would otherwise be again included in the income of such... are distributed to such shareholder directly, or indirectly through a chain of ownership described in...

75 FR 5035 - Notice of Intent To Grant Exclusive License

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... DEPARTMENT OF AGRICULTURE Agricultural Research Service Notice of Intent To Grant Exclusive License AGENCY: Agricultural Research Service, USDA. ACTION: Notice of intent. SUMMARY: Notice is hereby..., ``Direct Polymerase Chain Reaction Assay, or Bio-PCR'', issued on June 25, 2002. DATES: Comments must be...

Immunoglobulin Heavy Chain Exclusion in the Shark

PubMed Central

Malecek, Karolina; Lee, Victor; Feng, Wendy; Huang, Jing Li; Flajnik, Martin F; Ohta, Yuko; Hsu, Ellen

2008-01-01

The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes. Adaptive responses to immune challenge are based on the expression of a single species of antigen receptor per cell; and in B cells, this is mediated in part by allelic exclusion at the Ig heavy (H) chain locus. How allelic exclusion is regulated is unclear; we considered that sharks, the oldest vertebrates possessing the Ig/TCR-based immune system, would yield insights not previously approachable and reveal the primordial basis of the regulation of allelic exclusion. Sharks have an IgH locus organization consisting of 15–200 independently rearranging miniloci (VH-D1-D2-JH-Cμ), a gene organization that is considered ancestral to the tetrapod and bony fish IgH locus. We found that rearrangement takes place only within a minilocus, and the recombining gene segments are assembled simultaneously and randomly. Only one or few H chain genes were fully rearranged in each shark B cell, whereas the other loci retained their germline configuration. In contrast, most IgH were partially rearranged in every thymocyte (developing T cell) examined, but no IgH transcripts were detected. The distinction between B and T cells in their IgH configurations and transcription reveals a heretofore unsuspected chromatin state permissive for rearrangement in precursor lymphocytes, and suggests that controlled limitation of B cell lineage-specific factors mediate regulated rearrangement and allelic exclusion. This regulation may be shared by higher vertebrates in which additional mechanistic and regulatory elements have evolved with their structurally complex IgH locus. PMID:18578572

Sentient Commodities and Productive Paradoxes: The Ambiguous Nature of Human-Livestock Relations in Northeast Scotland

ERIC Educational Resources Information Center

Wilkie, R.

2005-01-01

The Curry Report (Policy Commission on the Future of Farming and Food, Farming and Food: A Sustainable Future (Curry Report), Cabinet Office, London, 2002) recently recommended that farmers 'reconnect' with their consumers, their markets and the food chain. In terms of livestock production this process of reconnection may not be so…

Current Status of Mycotoxin Contamination of Food Commodities in Zimbabwe.

PubMed

Nleya, Nancy; Adetunji, Modupeade Christianah; Mwanza, Mulunda

2018-05-03

Agricultural products, especially cereal grains, serve as staple foods in sub-Saharan Africa. However, climatic conditions in this region can lead to contamination of these commodities by moulds, with subsequent production of mycotoxins posing health risks to both humans and animals. There is limited documentation on the occurrence of mycotoxins in sub-Saharan African countries, leading to the exposure of their populations to a wide variety of mycotoxins through consumption of contaminated foods. This review aims at highlighting the current status of mycotoxin contamination of food products in Zimbabwe and recommended strategies of reducing this problem. Zimbabwe is one of the African countries with very little information with regards to mycotoxin contamination of its food commodities, both on the market and at household levels. Even though evidence of multitoxin occurrence in some food commodities such as maize and other staple foods exist, available published research focuses only on Aspergillus and Fusarium mycotoxins, namely aflatoxins, deoxynivalenol (DON), trichothecenes, fumonisins, and zearalenone (ZEA). Occurrence of mycotoxins in the food chain has been mainly associated with poor agricultural practices. Analysis of mycotoxins has been done mainly using chromatographic and immunological methods. Zimbabwe has adopted European standards, but the legislation is quite flexible, with testing for mycotoxin contamination in food commodities being done voluntarily or upon request. Therefore, the country needs to tighten its legislation as well as adopt stricter standards that will improve the food safety and security of the masses.

Change in IgHV Mutational Status of CLL Suggests Origin From Multiple Clones.

PubMed

Osman, Afaf; Gocke, Christopher D; Gladstone, Douglas E

2017-02-01

Fluorescence in situ hybridization and immunoglobulin (Ig) heavy-chain variable-region (IgHV) mutational status are used to predict outcome in chronic lymphocytic leukemia (CLL). Although DNA aberrations change over time, IgHV sequences and mutational status are considered stable. In a retrospective review, 409 CLL patients, between 2008 and 2015, had IgHV analysis: 56 patients had multiple analyses performed. Seven patients' IgHV results changed: 2 from unmutated to mutated and 5 from mutated to unmutated IgHV sequence. Three concurrently changed their variable heavy-chain sequence. Secondary to allelic exclusion, 2 of the new variable heavy chains produced were biologically nonplausible. The existence of these new nonplausible heavy-chain variable regions suggests either the CLL cancer stem-cell maintains the ability to rearrange a previously silenced IgH allele or more likely that the cancer stem-cell produced at least 2 subclones, suggesting that the CLL cancer stem cell exists before the process of allelic exclusion occurs. Copyright © 2016 Elsevier Inc. All rights reserved.

TROSY of side-chain amides in large proteins

PubMed Central

Liu, Aizhuo; Yao, Lishan; Li, Yue; Yan, Honggao

2012-01-01

By using the mixed solvent of 50% H2O/50% D2O and employing deuterium decoupling, TROSY experiments exclusively detect NMR signals from semideuterated isotopomers of carboxamide groups with high sensitivities for proteins with molecular weights up to 80 kDa. This isotopomer-selective strategy extends TROSY experiments from exclusively detecting backbone to both backbone and side-chain amides, particularly in large proteins. Because of differences in both TROSY effect and dynamics between 15N–HE{DZ} and 15N–HZ{DE} isotopomers of the same carboxamide, the 15N transverse magnetization of the latter relaxes significantly faster than that of the former, which provides a direct and reliable stereospecific distinction between the two configurations. The TROSY effects on the 15N–HE{DZ} isotopomers of side-chain amides are as significant as on backbone amides. PMID:17347000

Myosin light chains: Teaching old dogs new tricks

PubMed Central

Heissler, Sarah M; Sellers, James R

2014-01-01

The myosin holoenzyme is a multimeric protein complex consisting of heavy chains and light chains. Myosin light chains are calmodulin family members which are crucially involved in the mechanoenzymatic function of the myosin holoenzyme. This review examines the diversity of light chains within the myosin superfamily, discusses interactions between the light chain and the myosin heavy chain as well as regulatory and structural functions of the light chain as a subunit of the myosin holoenzyme. It covers aspects of the myosin light chain in the localization of the myosin holoenzyme, protein-protein interactions and light chain binding to non-myosin binding partners. Finally, this review challenges the dogma that myosin regulatory and essential light chain exclusively associate with conventional myosin heavy chains while unconventional myosin heavy chains usually associate with calmodulin. PMID:26155737

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

PubMed Central

1995-01-01

We have examined the extent of allelic exclusion at the T cell receptor (TCR) beta locus using monoclonal antibodies specific for V beta products. A small proportion (approximately 1%) of human peripheral blood T cells express two V beta as determined by flow cytometric analysis, isolation of representative clones, and sequencing of the corresponding V beta chains. Dual beta T cells are present in both the CD45R0+ and CD45R0- subset. These results indicate that dual beta expression is compatible with both central and peripheral selection. They also suggest that the substantial degree of TCR beta allelic exclusion is dependent only on asynchronous rearrangements at the beta locus, whereas the role of the pre-TCR is limited to signaling the presence of at least one functional beta protein. PMID:7699339

An Interactive Microcomputer Program for Teaching the Impacts of Alternative Policy Sets in the Market for a Single Commodity.

ERIC Educational Resources Information Center

Li, Elton; Stoecker, Arthur

1995-01-01

Describes a computer software program where students define alternative policy sets and compare their effects on the welfare of consumers, producers, and the public sector. Policy sets may be a single tax or quota or a mix of taxes, subsidies, and/or price supports implemented in the marketing chain. (MJP)

The natural radioactivity in some Nigerian foodstuffs

NASA Astrophysics Data System (ADS)

Olomo, James B.

1990-12-01

The average activity concentrations of seven locally produced food commodities that form the total diets of a baby, a teenager or an adult male in Nigeria were measured by means of a well-calibrated high-resolution lithium-drifted germanium (Ge(Li)) spectrometer system. The food commodities were collected at several centers such as a nuclear research center as well as metropolitan and industrial areas. The emission lines identified with reliable regularity belonged to the 238U and 232Th decay series. The other isotope is a non-related naturally occurring radionuclide, 40K. Average total specific-activity values of 7.29 ± 1.08, 6.27 ± 1.01 and 11.23 ± 1.64 Bq/kg for 238U, 232Th and 40K, respectively, were obtained for the seven food commodities studied. The food samples were also checked for fission-product residues ( 137Cs and 90Sr) from atmospheric weapons tests which are slowly being purged from the food chain. Their estimation revealed that they were below the minimum detectable limit determined at a two-standard deviation analytical error.

Substantial nitrogen pollution embedded in international trade

NASA Astrophysics Data System (ADS)

Oita, Azusa; Malik, Arunima; Kanemoto, Keiichiro; Geschke, Arne; Nishijima, Shota; Lenzen, Manfred

2016-02-01

Anthropogenic emissions of reactive nitrogen to the atmosphere and water bodies can damage human health and ecosystems. As a measure of a nation’s contribution to this potential damage, a country’s nitrogen footprint has been defined as the quantity of reactive nitrogen emitted during the production, consumption and transportation of commodities consumed within that country, whether those commodities are produced domestically or internationally. Here we use global emissions databases, a global nitrogen cycle model, and a global input-output database of domestic and international trade to calculate the nitrogen footprints for 188 countries as the sum of emissions of ammonia, nitrogen oxides and nitrous oxide to the atmosphere, and of nitrogen potentially exportable to water bodies. Per-capita footprints range from under 7 kg N yr-1 in some developing countries to over 100 kg N yr-1 in some wealthy nations. Consumption in China, India, the United States and Brazil is responsible for 46% of global emissions. Roughly a quarter of the global nitrogen footprint is from commodities that were traded across country borders. The main net exporters have significant agricultural, food and textile exports, and are often developing countries, whereas important net importers are almost exclusively developed economies. We conclude that substantial local nitrogen pollution is driven by demand from consumers in other countries.

Strategic contracting practices to improve procurement of health commodities

PubMed Central

Arney, Leslie; Yadav, Prashant; Miller, Roger; Wilkerson, Taylor

2014-01-01

ABSTRACT Public-sector entities responsible for procurement of essential medicines and health commodities in developing countries often lack the technical capacity to efficiently ensure supply security. Under strict public scrutiny and pressures to be transparent, many agencies continue to use archaic procurement methods and to depend on inflexible forecasts and cumbersome tendering processes. On the basis of semi-structured literature reviews and interviews, we identified framework agreements as a strategic procurement practice used by the U.S. federal government that may also be suitable for global health supply chains. Framework agreements are long-term contracts that provide the terms and conditions under which smaller repeat purchasing orders may be issued for a defined period of time. Such agreements are common in U.S. and United Nations procurement systems and in other developed countries and multilateral organizations. In contrast, framework agreements appear to be seldom used in procurement of health commodities in countries of sub-Saharan Africa. The current practice of floating tenders multiple times a year contributes to long lead times and stock-outs, and it hampers the manufacturer's or supplier's ability to plan and respond to the government's needs. To date, government's use of strategic contracting practices in public procurement of health commodities has not received much attention in most developing countries. It may present an opportunity for substantial improvements in procurement efficiency and commodity availability. Enabling legislation and strengthened technical capacity to develop and manage long-term contracts could facilitate the use of framework contracts in sub-Saharan Africa, with improved supply security and cost savings likely to result. PMID:25276589

Strategic contracting practices to improve procurement of health commodities.

PubMed

Arney, Leslie; Yadav, Prashant; Miller, Roger; Wilkerson, Taylor

2014-08-01

Public-sector entities responsible for procurement of essential medicines and health commodities in developing countries often lack the technical capacity to efficiently ensure supply security. Under strict public scrutiny and pressures to be transparent, many agencies continue to use archaic procurement methods and to depend on inflexible forecasts and cumbersome tendering processes. On the basis of semi-structured literature reviews and interviews, we identified framework agreements as a strategic procurement practice used by the U.S. federal government that may also be suitable for global health supply chains. Framework agreements are long-term contracts that provide the terms and conditions under which smaller repeat purchasing orders may be issued for a defined period of time. Such agreements are common in U.S. and United Nations procurement systems and in other developed countries and multilateral organizations. In contrast, framework agreements appear to be seldom used in procurement of health commodities in countries of sub-Saharan Africa. The current practice of floating tenders multiple times a year contributes to long lead times and stock-outs, and it hampers the manufacturer's or supplier's ability to plan and respond to the government's needs. To date, government's use of strategic contracting practices in public procurement of health commodities has not received much attention in most developing countries. It may present an opportunity for substantial improvements in procurement efficiency and commodity availability. Enabling legislation and strengthened technical capacity to develop and manage long-term contracts could facilitate the use of framework contracts in sub-Saharan Africa, with improved supply security and cost savings likely to result.

75 FR 56858 - Exclusions From Gross Income of Foreign Corporations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-17

..., the foreign corporation cannot rely on bearer shares issued at any level in the ownership chain to... in the chain of ownership may not be relied on for purposes of satisfying a stock ownership test... block of stock to preclude nonqualified shareholders in the closely-held block of stock from owning 50...

Noise in tunneling spin current across coupled quantum spin chains

NASA Astrophysics Data System (ADS)

Aftergood, Joshua; Takei, So

2018-01-01

We theoretically study the spin current and its dc noise generated between two spin-1 /2 spin chains weakly coupled at a single site in the presence of an over-population of spin excitations and a temperature elevation in one subsystem relative to the other, and we compare the corresponding transport quantities across two weakly coupled magnetic insulators hosting magnons. In the spin chain scenario, we find that applying a temperature bias exclusively leads to a vanishing spin current and a concomitant divergence in the spin Fano factor, defined as the spin current noise-to-signal ratio. This divergence is shown to have an exact analogy to the physics of electron scattering between fractional quantum Hall edge states and not to arise in the magnon scenario. We also reveal a suppression in the spin current noise that exclusively arises in the spin chain scenario due to the fermion nature of the spin-1/2 operators. We discuss how the spin Fano factor may be extracted experimentally via the inverse spin Hall effect used extensively in spintronics.

Putting Place on the Menu: The Negotiation of Locality in UK Food Tourism, from Production to Consumption

ERIC Educational Resources Information Center

Sims, Rebecca

2010-01-01

This paper uses a case study of tourism in the Lake District and Exmoor to explore the relationship between "local food" and sustainable rural tourism in the UK. Drawing on qualitative interviews with tourists, food producers and cafe, pub and restaurant owners, I use an approach based upon the commodity chain to trace the shifts in the…

ALLOTYPE EXCLUSION IN UNIFORM RABBIT ANTIBODY TO STREPTOCOCCAL CARBOHYDRATE

PubMed Central

Kindt, Thomas J.; Todd, Charles W.; Eichmann, Klaus; Krause, Richard M.

1970-01-01

Rabbit antibodies to streptococcal polysaccharide are described which show selectivity of expression of the allotypic specificities on both the heavy (H) and light (L) chains. One of these antibodies binds weakly to Sephadex. A purification method based on this binding has yielded antibody completely lacking any group a allotypic marker on its H chains. PMID:5419853

Biosynthesis of monomers for plastics from renewable oils.

PubMed

Lu, Wenhua; Ness, Jon E; Xie, Wenchun; Zhang, Xiaoyan; Minshull, Jeremy; Gross, Richard A

2010-11-03

Omega-hydroxyfatty acids are excellent monomers for synthesizing a unique family of polyethylene-like biobased plastics. However, ω-hydroxyfatty acids are difficult and expensive to prepare by traditional organic synthesis, precluding their use in commodity materials. Here we report the engineering of a strain of the diploid yeast Candida tropicalis to produce commercially viable yields of ω-hydroxyfatty acids. To develop the strain we identified and eliminated 16 genes encoding 6 cytochrome P450s, 4 fatty alcohol oxidases, and 6 alcohol dehydrogenases from the C. tropicalis genome. We also show that fatty acids with different chain lengths and degrees of unsaturation can be more efficiently oxidized by expressing different P450s within this strain background. Biocatalysis using engineered C. tropicalis is thus a potentially attractive biocatalytic platform for producing commodity chemicals from renewable resources.

Optimising the laboratory supply chain: The key to effective laboratory services

PubMed Central

Williams, Jason; Smith, Peter; Kuritsky, Joel

2014-01-01

Background The Supply Chain Management System (SCMS) is a contract managed under the Partnership for Supply Chain Management (PFSCM) consortium by the United States Agency for International Development (USAID). SCMS procures commodities for programmes supported by the US President’s Emergency Plan for AIDS Relief (PEPFAR). From 2005 to mid-2012, PEPFAR, through SCMS, spent approximately $384 million on non-pharmaceutical commodities. Of this, an estimated $90m was used to purchase flow cytometry technology, largely for flow cytometry platforms and reagents. Objectives The purpose of this paper is to highlight the cost differences between low, medium and high utilisation rates of common CD4 testing instruments that have been procured though PEPFAR funding. Method A scale of costs per test as a function of test volume through the machine was calculated for the two most common CD4 testing machines used in HIV programmes: Becton Dickinson (BD) FACSCount™ and BD FACSCalibur™. Instrument utilisation data collected at the facility level in three selected countries were then used to calculate the onsite cost-per-test experienced in each country. Results Cost analyses indicated that a target of at least 40% utilisation for FACSCount™ and 15% utilisation for FACSCalibur™, respectively, closely approach maximal per-test cost efficiency. The average utilisation rate for CD4 testing instruments varies widely by country, level of laboratory and partner (0% − 68%). Conclusion Our analysis indicates that, because cost-per-test is related inversely to sample throughput, the underutilisation of flow cytometry machines is resulting in an increase in average cost-per-test for many instruments. PMID:29043175

International trade drives biodiversity threats in developing nations.

PubMed

Lenzen, M; Moran, D; Kanemoto, K; Foran, B; Lobefaro, L; Geschke, A

2012-06-06

Human activities are causing Earth's sixth major extinction event-an accelerating decline of the world's stocks of biological diversity at rates 100 to 1,000 times pre-human levels. Historically, low-impact intrusion into species habitats arose from local demands for food, fuel and living space. However, in today's increasingly globalized economy, international trade chains accelerate habitat degradation far removed from the place of consumption. Although adverse effects of economic prosperity and economic inequality have been confirmed, the importance of international trade as a driver of threats to species is poorly understood. Here we show that a significant number of species are threatened as a result of international trade along complex routes, and that, in particular, consumers in developed countries cause threats to species through their demand of commodities that are ultimately produced in developing countries. We linked 25,000 Animalia species threat records from the International Union for Conservation of Nature Red List to more than 15,000 commodities produced in 187 countries and evaluated more than 5 billion supply chains in terms of their biodiversity impacts. Excluding invasive species, we found that 30% of global species threats are due to international trade. In many developed countries, the consumption of imported coffee, tea, sugar, textiles, fish and other manufactured items causes a biodiversity footprint that is larger abroad than at home. Our results emphasize the importance of examining biodiversity loss as a global systemic phenomenon, instead of looking at the degrading or polluting producers in isolation. We anticipate that our findings will facilitate better regulation, sustainable supply-chain certification and consumer product labelling.

Multi-scale process and supply chain modelling: from lignocellulosic feedstock to process and products

PubMed Central

Hosseini, Seyed Ali; Shah, Nilay

2011-01-01

There is a large body of literature regarding the choice and optimization of different processes for converting feedstock to bioethanol and bio-commodities; moreover, there has been some reasonable technological development in bioconversion methods over the past decade. However, the eventual cost and other important metrics relating to sustainability of biofuel production will be determined not only by the performance of the conversion process, but also by the performance of the entire supply chain from feedstock production to consumption. Moreover, in order to ensure world-class biorefinery performance, both the network and the individual components must be designed appropriately, and allocation of resources over the resulting infrastructure must effectively be performed. The goal of this work is to describe the key challenges in bioenergy supply chain modelling and then to develop a framework and methodology to show how multi-scale modelling can pave the way to answer holistic supply chain questions, such as the prospects for second generation bioenergy crops. PMID:22482032

Quality and safety of herbal medical products: regulation and the need for quality assurance along the value chains.

PubMed

Heinrich, Michael

2015-07-01

Herbal medicines and products derived from them are a diverse group of products for which different (and often limited) levels of evidence are available. As importantly, such products generally vary in their composition and are at the end of an often poorly understood value chain, which often links producers in biodiversity rich countries with the large markets in the North. This paper discusses the current regulatory framework of such herbal medical products (with a focus on the UK) and using examples from our own metabolomic research on Curcumal longa L. (turmeric, Zingiberaceae) how value chains impact on the composition and quality (and thus the safety) of such products. Overall, our recent research demonstrates the need for studying the links between producers and consumers of commodities produced in provider countries and that plant metabolomics offer a novel way of assessing the chemical variability along a value chain. © 2015 The British Pharmacological Society.

Compilation of geospatial data for the mineral industries and related infrastructure of Latin America and the Caribbean

USGS Publications Warehouse

Baker, Michael S.; Buteyn, Spencer D.; Freeman, Philip A.; Trippi, Michael H.; Trimmer III, Loyd M.

2017-07-31

This report describes the U.S. Geological Survey’s (USGS) ongoing commitment to its mission of understanding the nature and distribution of global mineral commodity supply chains by updating and publishing the georeferenced locations of mineral commodity production and processing facilities, mineral exploration and development sites, and mineral commodity exporting ports in Latin America and the Caribbean. The report includes an overview of data sources and an explanation of the geospatial PDF map format.The geodatabase and geospatial data layers described in this report create a new geographic information product in the form of a geospatial portable document format (PDF) map. The geodatabase contains additional data layers from USGS, foreign governmental, and open-source sources as follows: (1) coal occurrence areas, (2) electric power generating facilities, (3) electric power transmission lines, (4) hydrocarbon resource cumulative production data, (5) liquefied natural gas terminals, (6) oil and gas concession leasing areas, (7) oil and gas field center points, (8) oil and gas pipelines, (9) USGS petroleum provinces, (10) railroads, (11) recoverable proven plus probable hydrocarbon resources, (12) major cities, (13) major rivers, and (14) undiscovered porphyry copper tracts.

An industry perspective on the use of seasonal forecasts and weather information for evaluating sensitivities in traded commodity supply chains

NASA Astrophysics Data System (ADS)

Domeisen, Daniela; Slavov, Georgi

2015-04-01

Weather information on seasonal timescales is crucial to various end users, from the level of subsistence farming to the government level. Also the financial industry is ever more aware of and interested in the benefits that early and correctly interpreted forecast information provides. Straight forward and often cited applications include the estimation of rainfall and temperature anomalies for drought - prone agricultural areas producing traded commodities, as well as some of the rather direct impacts of weather on energy production. Governments, weather services, as well as both academia and private companies are working on tailoring climate and weather information to a growing number of customers. However, also other large markets, such as coal, iron ore, and gas, are crucially dependent on seasonal weather information and forecasts, while the needs are again very dependent on the direction of the predicted signal. So far, relatively few providers in climate services address these industries. All of these commodities show a strong seasonal and weather dependence, and an unusual winter or summer can crucially impact their demand and supply. To name a few impacts, gas is crucially driven by heating demand, iron ore excavation is dependent on the available water resources, and coal mining is dependent on winter temperatures and rainfall. This contribution will illustrate and provide an inside view of the type of climate and weather information needed for the various large commodity industries.

Inventory transparency for agricultural produce through IOT

NASA Astrophysics Data System (ADS)

Srinivasan, S. P.; Sorna Shanthi, D.; Anand, Aashish V.

2017-06-01

Re-structuring the practices of traditional inventory management is becoming more essential to optimize the supply chain transparency and accuracy of agricultural produce. A flexible and transparent inventory management system is becoming the need of any agricultural commodity. It was noticed that the major setback for the farmers who are the suppliers of the farm produce is due to poor supply chain integration. The recent advent technologies and IT explosion can bring up a greater impact in the process of storing, tracking, distributing and monitoring perishable agriculture produce of day to day life. The primary focus of this paper is to integrate IoT into inventory management and other inbound logistics management of agriculture produce. The unique features of agricultural produce like a prediction of supply, demand, the location of warehouses, distribution and tracking of inventory can be integrated through IoT. This paper proposes a conceptual framework for inventory management transparency involved in the supply chain of agriculture produce.

A half-century of production-phase greenhouse gas emissions from food loss & waste in the global food supply chain.

PubMed

Porter, Stephen D; Reay, David S; Higgins, Peter; Bomberg, Elizabeth

2016-11-15

Research on loss & waste of food meant for human consumption (FLW) and its environmental impact typically focuses on a single or small number of commodities in a specific location and point in time. However, it is unclear how trends in global FLW and potential for climate impact have evolved. Here, by utilising the Food and Agriculture Organization's food balance sheet data, we expand upon existing literature. Firstly, we provide a differentiated (by commodity, country and supply chain stage) bottom-up approach; secondly, we conduct a 50-year longitudinal analysis of global FLW and its production-phase greenhouse gas (GHG) emissions; and thirdly, we trace food wastage and its associated emissions through the entire food supply chain. Between 1961 and 2011 the annual amount of FLW by mass grew a factor of three - from 540Mt to 1.6Gt; associated production-phase (GHG) emissions more than tripled (from 680Mt to 2.2Gt CO2e). A 44% increase in global average per capita FLW emissions was also identified - from 225kg CO2e in 1961 to 323kg CO2e in 2011. The regional weighting within this global average changing markedly over time; in 1961 developed countries accounted for 48% of FLW and less than a quarter (24%) in 2011. The largest increases in FLW-associated GHG emissions were from developing economies, specifically China and Latin America - primarily from increasing losses in fruit and vegetables. Over the period examined, cumulatively such emissions added almost 68Gt CO2e to the atmospheric GHG stock; an amount the rough equivalent of two years of emissions from all anthropogenic sources at present rates. Building up from the most granular data available, this study highlights the growth in the climate burden of FLW emissions, and thus the need to improve efficiency in food supply chains to mitigate future emissions. Copyright © 2016 Elsevier B.V. All rights reserved.

The influence of maturity of VMAC5 (Cocos nucifera L. ‘makapuno’) on its physicochemical, proximate composition and fatty acid profile

NASA Astrophysics Data System (ADS)

Leorna, M.; Israel, K. A.

2018-01-01

“Makapuno” is one of the promising commodities of the Philippines with good nutritional quality. VMAC5 is the most recent “makapuno” variety developed by the Visayas State University, Baybay City, Leyte, Philippines. Maximum utilization of this commodity is dependent on its thorough characterization. This study aimed to determine the influence of nut maturity on its physicochemical, proximate composition and fatty acid profile. Results revealed that VMAC5 nuts were affected by maturity. An 8-month old nuts exhibited heavier weight compared to mature nuts. The total sugar decreased with maturity. TSS and pH were not affected by maturity. Proximate composition were affected by maturity with moisture content of 59.17-86.88%, crude protein of 1.58-2.62%, crude fiber of 2.24-5.43% and crude fat of 3.06-12.14% of which >50% were medium chain fatty acids (MCFA).

Urbanization and international trade and investment policies as determinants of noncommunicable diseases in Sub-Saharan Africa.

PubMed

Schram, Ashley; Labonté, Ronald; Sanders, David

2013-01-01

There are three dominant globalization pathways affecting noncommunicable diseases in Sub-Saharan Africa (SSA): urbanization, trade liberalization, and investment liberalization. Urbanization carries potential health benefits due to improved access to an increased variety of food imports, although for the growing number of urban poor, this has often meant increased reliance on cheap, highly processed food commodities. Reduced barriers to trade have eased the importation of such commodities, while investment liberalization has increased corporate consolidation over global and domestic food chains. Higher profit margins on processed foods have promoted the creation of 'obesogenic' environments, which through progressively integrated global food systems have been increasingly 'exported' to developing nations. This article explores globalization processes, the food environment, and dietary health outcomes in SSA through the use of trend analyses and structural equation modelling. The findings are considered in the context of global barriers and facilitators for healthy public policy. © 2013.

Engineering cyanobacteria for direct biofuel production from CO2.

PubMed

Savakis, Philipp; Hellingwerf, Klaas J

2015-06-01

For a sustainable future of our society it is essential to close the global carbon cycle. Oxidised forms of carbon, in particular CO2, can be used to synthesise energy-rich organic molecules. Engineered cyanobacteria have attracted attention as catalysts for the direct conversion of CO2 into reduced fuel compounds. Proof of principle for this approach has been provided for a vast range of commodity chemicals, mostly energy carriers, such as short chain and medium chain alcohols. More recently, research has focused on the photosynthetic production of compounds with higher added value, most notably terpenoids. Below we review the recent developments that have improved the state-of-the-art of this approach and speculate on future developments. Copyright © 2014 Elsevier Ltd. All rights reserved.

Evidence for Ig Light Chain Isotype Exclusion in Shark B Lymphocytes Suggests Ordered Mechanisms.

PubMed

Iacoangeli, Anna; Lui, Anita; Haines, Ashley; Ohta, Yuko; Flajnik, Martin; Hsu, Ellen

2017-09-01

Unlike most vertebrates, the shark IgL gene organization precludes secondary rearrangements that delete self-reactive VJ rearranged genes. Nurse sharks express four L chain isotypes, κ, λ, σ, and σ-2, encoded by 35 functional minigenes or clusters. The sequence of gene activation/expression and receptor editing of these isotypes have not been studied. We therefore investigated the extent of isotypic exclusion in separated B cell subpopulations. Surface Ig (sIg)κ-expressing cells, isolated with mAb LK14 that recognizes Cκ, carry predominantly nonproductive rearrangements of other L chain isotypes. Conversely, after depletion with LK14, sIgM + cells contained largely nonproductive κ and enrichment for in-frame VJ of the others. Because some isotypic inclusion was observed at the mRNA level, expression in the BCR was examined. Functional λ mRNA was obtained, as expected, from the LK14-depleted population, but was also in sIgκ + splenocytes. Whereas λ somatic mutants from the depleted sample displayed evidence of positive selection, the λ genes in sIgκ + cells accumulated bystander mutations indicating a failure to express their products at the cell surface in association with the BCR H chain. In conclusion, a shark B cell expresses one L chain isotype at the surface and other isotypes as nonproductive VJ, sterile transcripts, or in-frame VJ whose products may not associate with the H chain. Based on the mRNA content found in the B cell subpopulations, an order of L chain gene activation is suggested as: σ-2 followed by κ, then σ and λ. Copyright © 2017 by The American Association of Immunologists, Inc.

Estimation of polyclonal IgG4 hybrids in normal human serum.

PubMed

Young, Elizabeth; Lock, Emma; Ward, Douglas G; Cook, Alexander; Harding, Stephen; Wallis, Gregg L F

2014-07-01

The in vivo or in vitro formation of IgG4 hybrid molecules, wherein the immunoglobulins have exchanged half molecules, has previously been reported under experimental conditions. Here we estimate the incidence of polyclonal IgG4 hybrids in normal human serum and comment on the existence of IgG4 molecules with different immunoglobulin light chains. Polyclonal IgG4 was purified from pooled or individual donor human sera and sequentially fractionated using light-chain affinity and size exclusion chromatography. Fractions were analysed by SDS-PAGE, immunoblotting, ELISA, immunodiffusion and matrix-assisted laser-desorption mass spectrometry. Polyclonal IgG4 purified from normal serum contained IgG4κ, IgG4λ and IgG4κ/λ molecules. Size exclusion chromatography showed that IgG4 was principally present in monomeric form (150 000 MW). SDS-PAGE, immunoblotting and ELISA showed the purity of the three IgG4 samples. Immunodiffusion, light-chain sandwich ELISA and mass spectrometry demonstrated that both κ and λ light chains were present on only the IgG4κ/λ molecules. The amounts of IgG4κ/λ hybrid molecules ranged from 21 to 33% from the five sera analysed. Based on the molecular weight these molecules were formed of two IgG4 heavy chains plus one κ and one λ light chain. Polyclonal IgG (IgG4-depleted) was similarly fractionated according to light-chain specificity. No evidence of hybrid IgG κ/λ antibodies was observed. These results indicate that hybrid IgG4κ/λ antibodies compose a substantial portion of IgG4 from normal human serum. © 2014 John Wiley & Sons Ltd.

Lipid Metabolism during Infection and Endotoxemia

DTIC Science & Technology

1981-01-01

containing 8- and 10-carbon fatty acids almost exclusively) have been used in certain therapeutic diets . In contrast to the long-chain triglycerides...increased utilization of ketone bodies. The major substrates for hepatic ketogenesis are long-chain fatty acids. The term ’ ketogenic capacity’ refers to the...bodies is influenced not only by substrate availability and enzyme activities, but also more directly by the dis- posal of acetyl-CoA through ketogenic

On the degelation of networks – Case of the radiochemical degradation of methyl methacrylate – ethylene glycol dimethacrylate copolymers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richaud, Emmanuel; Gilormini, Pierre; Verdu, Jacques

2016-05-18

Methyl methacrylate networks were synthetized and submitted to radiochemical degradation. Ageing was monitored by means of sol-gel analysis and glass transition temperature measurements. Networks were shown to undergo exclusively chain scission process leading to the degelation of network. The critical conversion degree corresponding to degelation (loss of all elastically active chains) is discussed regarding a statistical theory.

Land-use policies and corporate investments in agriculture in the Gran Chaco and Chiquitano

PubMed Central

le Polain de Waroux, Yann; Garrett, Rachael D.; Heilmayr, Robert; Lambin, Eric F.

2016-01-01

Growing demand for agricultural commodities is causing the expansion of agricultural frontiers onto native vegetation worldwide. Agribusiness companies linking these frontiers to distant spaces of consumption through global commodity chains increasingly make zero-deforestation pledges. However, production and land conversion are often carried out by less-visible local and regional actors that are mobile and responsive to new agricultural expansion opportunities and legal constraints on land use. With more stringent deforestation regulations in some countries, we ask whether their movements are determined partly by differences in land-use policies, resulting in “deforestation havens.” We analyze the determinants of investment decisions by agricultural companies in the Gran Chaco and Chiquitano, a region that has become the new deforestation “hot spot” in South America. We test whether companies seek out less-regulated forest areas for new agricultural investments. Based on interviews with 82 companies totaling 2.5 Mha of properties, we show that, in addition to proximity to current investments and the availability of cheap forestland, lower deforestation regulations attract investments by companies that tend to clear more forest, mostly cattle ranching operations, and that lower enforcement attracts all companies. Avoiding deforestation leakage requires harmonizing deforestation regulations across regions and commodities and promoting sustainable intensification in cattle ranching. PMID:27035995

Land-use policies and corporate investments in agriculture in the Gran Chaco and Chiquitano.

PubMed

le Polain de Waroux, Yann; Garrett, Rachael D; Heilmayr, Robert; Lambin, Eric F

2016-04-12

Growing demand for agricultural commodities is causing the expansion of agricultural frontiers onto native vegetation worldwide. Agribusiness companies linking these frontiers to distant spaces of consumption through global commodity chains increasingly make zero-deforestation pledges. However, production and land conversion are often carried out by less-visible local and regional actors that are mobile and responsive to new agricultural expansion opportunities and legal constraints on land use. With more stringent deforestation regulations in some countries, we ask whether their movements are determined partly by differences in land-use policies, resulting in "deforestation havens." We analyze the determinants of investment decisions by agricultural companies in the Gran Chaco and Chiquitano, a region that has become the new deforestation "hot spot" in South America. We test whether companies seek out less-regulated forest areas for new agricultural investments. Based on interviews with 82 companies totaling 2.5 Mha of properties, we show that, in addition to proximity to current investments and the availability of cheap forestland, lower deforestation regulations attract investments by companies that tend to clear more forest, mostly cattle ranching operations, and that lower enforcement attracts all companies. Avoiding deforestation leakage requires harmonizing deforestation regulations across regions and commodities and promoting sustainable intensification in cattle ranching.

Engineering acyl carrier protein to enhance production of shortened fatty acids.

PubMed

Liu, Xueliang; Hicks, Wade M; Silver, Pamela A; Way, Jeffrey C

2016-01-01

The acyl carrier protein (ACP) is an essential and ubiquitous component of microbial synthesis of fatty acids, the natural precursor to biofuels. Natural fatty acids usually contain long chains of 16 or more carbon atoms. Shorter carbon chains, with increased fuel volatility, are desired for internal combustion engines. Engineering the length specificity of key proteins in fatty acid metabolism, such as ACP, may enable microbial synthesis of these shorter chain fatty acids. We constructed a homology model of the Synechococcus elongatus ACP, showing a hydrophobic pocket harboring the growing acyl chain. Amino acids within the pocket were mutated to increase steric hindrance to the acyl chain. Certain mutant ACPs, when over-expressed in Escherichia coli, increased the proportion of shorter chain lipids; I75 W and I75Y showed the strongest effects. Expression of I75 W and I75Y mutant ACPs also increased production of lauric acid in E. coli that expressed the C12-specific acyl-ACP thioesterase from Cuphea palustris. We engineered the specificity of the ACP, an essential protein of fatty acid metabolism, to alter the E. coli lipid pool and enhance production of medium-chain fatty acids as biofuel precursors. These results indicate that modification of ACP itself could be combined with enzymes affecting length specificity in fatty acid synthesis to enhance production of commodity chemicals based on fatty acids.

Irreversible Local Markov Chains with Rapid Convergence towards Equilibrium.

PubMed

Kapfer, Sebastian C; Krauth, Werner

2017-12-15

We study the continuous one-dimensional hard-sphere model and present irreversible local Markov chains that mix on faster time scales than the reversible heat bath or Metropolis algorithms. The mixing time scales appear to fall into two distinct universality classes, both faster than for reversible local Markov chains. The event-chain algorithm, the infinitesimal limit of one of these Markov chains, belongs to the class presenting the fastest decay. For the lattice-gas limit of the hard-sphere model, reversible local Markov chains correspond to the symmetric simple exclusion process (SEP) with periodic boundary conditions. The two universality classes for irreversible Markov chains are realized by the totally asymmetric SEP (TASEP), and by a faster variant (lifted TASEP) that we propose here. We discuss how our irreversible hard-sphere Markov chains generalize to arbitrary repulsive pair interactions and carry over to higher dimensions through the concept of lifted Markov chains and the recently introduced factorized Metropolis acceptance rule.

Irreversible Local Markov Chains with Rapid Convergence towards Equilibrium

NASA Astrophysics Data System (ADS)

Kapfer, Sebastian C.; Krauth, Werner

2017-12-01

We study the continuous one-dimensional hard-sphere model and present irreversible local Markov chains that mix on faster time scales than the reversible heat bath or Metropolis algorithms. The mixing time scales appear to fall into two distinct universality classes, both faster than for reversible local Markov chains. The event-chain algorithm, the infinitesimal limit of one of these Markov chains, belongs to the class presenting the fastest decay. For the lattice-gas limit of the hard-sphere model, reversible local Markov chains correspond to the symmetric simple exclusion process (SEP) with periodic boundary conditions. The two universality classes for irreversible Markov chains are realized by the totally asymmetric SEP (TASEP), and by a faster variant (lifted TASEP) that we propose here. We discuss how our irreversible hard-sphere Markov chains generalize to arbitrary repulsive pair interactions and carry over to higher dimensions through the concept of lifted Markov chains and the recently introduced factorized Metropolis acceptance rule.

Trading forests: land-use change and carbon emissions embodied in production and exports of forest-risk commodities

NASA Astrophysics Data System (ADS)

Henders, Sabine; Persson, U. Martin; Kastner, Thomas

2015-12-01

Production of commercial agricultural commodities for domestic and foreign markets is increasingly driving land clearing in tropical regions, creating links and feedback effects between geographically separated consumption and production locations. Such teleconnections are commonly studied through calculating consumption footprints and quantifying environmental impacts embodied in trade flows, e.g., virtual water and land, biomass, or greenhouse gas emissions. The extent to which land-use change (LUC) and associated carbon emissions are embodied in the production and export of agricultural commodities has been less studied. Here we quantify tropical deforestation area and carbon emissions from LUC induced by the production and the export of four commodities (beef, soybeans, palm oil, and wood products) in seven countries with high deforestation rates (Argentina, Bolivia, Brazil, Paraguay, Indonesia, Malaysia, and Papua New Guinea). We show that in the period 2000-2011, the production of the four analyzed commodities in our seven case countries was responsible for 40% of total tropical deforestation and resulting carbon losses. Over a third of these impacts was embodied in exports in 2011, up from a fifth in 2000. This trend highlights the growing influence of global markets in deforestation dynamics. Main flows of embodied LUC are Latin American beef and soybean exports to markets in Europe, China, the former Soviet bloc, the Middle East and Northern Africa, whereas embodied emission flows are dominated by Southeast Asian exports of palm oil and wood products to consumers in China, India and the rest of Asia, as well as to the European Union. Our findings illustrate the growing role that global consumers play in tropical LUC trajectories and highlight the need for demand-side policies covering whole supply chains. We also discuss the limitations of such demand-side measures and call for a combination of supply- and demand-side policies to effectively limit tropical deforestation, along with research into the interactions of different types of policy interventions.

Is voluntary certification of tropical agricultural commodities achieving sustainability goals for small-scale producers? A review of the evidence

NASA Astrophysics Data System (ADS)

DeFries, Ruth S.; Fanzo, Jessica; Mondal, Pinki; Remans, Roseline; Wood, Stephen A.

2017-03-01

Over the last several decades, voluntary certification programs have become a key approach to promote sustainable supply chains for agricultural commodities. These programs provide premiums and other benefits to producers for adhering to environmental and labor practices established by the certifying entities. Following the principles of Cochrane Reviews used in health sciences, we assess evidence to evaluate whether voluntary certification of tropical agricultural commodities (bananas, cocoa, coffee, oil palm, and tea) has achieved environmental benefits and improved economic and social outcomes for small-scale producers at the level of the farm household. We reviewed over 2600 papers in the peer-review literature and identified 24 cases of unique combinations of study area, certification program, and commodity in 16 papers that rigorously analyzed differences between treatment (certified households) and control groups (uncertified households) for a wide range of response variables. Based on analysis of 347 response variables reported in these papers, we conclude that certification is associated on average with positive outcomes for 34% of response variables, no significant difference for 58% of variables, and negative outcomes for 8% of variables. No significant differences were observed for different categories of responses (environmental, economic and social) or for different commodities (banana, coffee and tea), except negative outcomes were significantly less for environmental than other outcome categories (p = 0.01). Most cases (20 out of 24) investigated coffee certification and response variables were inconsistent across cases, indicating the paucity of studies to conduct a conclusive meta-analysis. The somewhat positive results indicate that voluntary certification programs can sometimes play a role in meeting sustainable development goals and do not support the view that such programs are merely greenwashing. However, results also indicate that certification is not a panacea to improve social outcomes or overall incomes of smallholder farmers. Rigorous analysis, standardized criteria, and independent evaluation are needed to assess effectiveness of certification programs in the future.

Shifting orders among suppliers considering risk, price and transportation cost

NASA Astrophysics Data System (ADS)

Revitasari, C.; Pujawan, I. N.

2018-04-01

Supplier order allocation is an important supply chain decision for an enterprise. It is related to the supplier’s function as a raw material provider and other supporting materials that will be used in production process. Most of works on order allocation has been based on costs and other supply chain performance, but very limited of them taking risks into consideration. In this paper we address the problem of order allocation of a single commodity sourced from multiple suppliers considering supply risks in addition to the attempt of minimizing transportation costs. The supply chain risk was investigated and a procedure was proposed in the risk mitigation phase as a form of risk profile. The objective including risk profile in order allocation is to maximize the product flow from a risky supplier to a relatively less risky supplier. The proposed procedure is applied to a sugar company. The result suggests that order allocations should be maximized to suppliers that have a relatively low risk and minimized to suppliers that have a relatively larger risks.

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells

PubMed Central

Holwerda, Sjoerd J. B.; van de Werken, Harmen J. G.; Ribeiro de Almeida, Claudia; Bergen, Ingrid M.; de Bruijn, Marjolein J. W.; Verstegen, Marjon J. A. M.; Simonis, Marieke; Splinter, Erik; Wijchers, Patrick J.; Hendriks, Rudi W.; de Laat, Wouter

2013-01-01

In developing B cells, the immunoglobulin heavy chain (IgH) locus is thought to move from repressive to permissive chromatin compartments to facilitate its scheduled rearrangement. In mature B cells, maintenance of allelic exclusion has been proposed to involve recruitment of the non-productive IgH allele to pericentromeric heterochromatin. Here, we used an allele-specific chromosome conformation capture combined with sequencing (4C-seq) approach to unambigously follow the individual IgH alleles in mature B lymphocytes. Despite their physical and functional difference, productive and non-productive IgH alleles in B cells and unrearranged IgH alleles in T cells share many chromosomal contacts and largely reside in active chromatin. In brain, however, the locus resides in a different repressive environment. We conclude that IgH adopts a lymphoid-specific nuclear location that is, however, unrelated to maintenance of allelic exclusion. We additionally find that in mature B cells—but not in T cells—the distal VH regions of both IgH alleles position themselves away from active chromatin. This, we speculate, may help to restrict enhancer activity to the productively rearranged VH promoter element. PMID:23748562

Egalitarian despots: hierarchy steepness, reciprocity and the grooming-trade model in wild chimpanzees, Pan troglodytes.

PubMed

Kaburu, Stefano S K; Newton-Fisher, Nicholas E

2015-01-01

Biological market theory models the action of natural selection as a marketplace in which animals are viewed as traders with commodities to offer and exchange. Studies of female Old World monkeys have suggested that grooming might be employed as a commodity to be reciprocated or traded for alternative services, yet previous tests of this grooming-trade model in wild adult male chimpanzees have yielded mixed results. Here we provide the strongest test of the model to date for male chimpanzees: we use data drawn from two social groups (communities) of chimpanzees from different populations and give explicit consideration to variation in dominance hierarchy steepness, as such variation results in differing conditions for biological markets. First, analysis of data from published accounts of other chimpanzee communities, together with our own data, showed that hierarchy steepness varied considerably within and across communities and that the number of adult males in a community aged 20-30 years predicted hierarchy steepness. The two communities in which we tested predictions of the grooming-trade model lay at opposite extremes of this distribution. Second, in accord with the grooming-trade model, we found evidence that male chimpanzees trade grooming for agonistic support where hierarchies are steep (despotic) and consequent effective support is a rank-related commodity, but not where hierarchies are shallow (egalitarian). However, we also found that grooming was reciprocated regardless of hierarchy steepness. Our findings also hint at the possibility of agonistic competition, or at least exclusion, in relation to grooming opportunities compromising the free market envisioned by biological market theory. Our results build on previous findings across chimpanzee communities to emphasize the importance of reciprocal grooming exchanges among adult male chimpanzees, which can be understood in a biological markets framework if grooming by or with particular individuals is a valuable commodity.

Egalitarian despots: hierarchy steepness, reciprocity and the grooming-trade model in wild chimpanzees, Pan troglodytes

PubMed Central

Kaburu, Stefano S. K.; Newton-Fisher, Nicholas E.

2014-01-01

Biological market theory models the action of natural selection as a marketplace in which animals are viewed as traders with commodities to offer and exchange. Studies of female Old World monkeys have suggested that grooming might be employed as a commodity to be reciprocated or traded for alternative services, yet previous tests of this grooming-trade model in wild adult male chimpanzees have yielded mixed results. Here we provide the strongest test of the model to date for male chimpanzees: we use data drawn from two social groups (communities) of chimpanzees from different populations and give explicit consideration to variation in dominance hierarchy steepness, as such variation results in differing conditions for biological markets. First, analysis of data from published accounts of other chimpanzee communities, together with our own data, showed that hierarchy steepness varied considerably within and across communities and that the number of adult males in a community aged 20–30 years predicted hierarchy steepness. The two communities in which we tested predictions of the grooming-trade model lay at opposite extremes of this distribution. Second, in accord with the grooming-trade model, we found evidence that male chimpanzees trade grooming for agonistic support where hierarchies are steep (despotic) and consequent effective support is a rank-related commodity, but not where hierarchies are shallow (egalitarian). However, we also found that grooming was reciprocated regardless of hierarchy steepness. Our findings also hint at the possibility of agonistic competition, or at least exclusion, in relation to grooming opportunities compromising the free market envisioned by biological market theory. Our results build on previous findings across chimpanzee communities to emphasize the importance of reciprocal grooming exchanges among adult male chimpanzees, which can be understood in a biological markets framework if grooming by or with particular individuals is a valuable commodity. PMID:25580017

Challenges and issues concerning mycotoxins contamination in oil seeds and their edible oils: Updates from last decade.

PubMed

Bhat, Rajeev; Reddy, Kasa Ravindra Nadha

2017-01-15

Safety concerns pertaining towards fungal occurrence and mycotoxins contamination in agri-food commodities has been an issue of high apprehension. With the increase in evidence based research knowledge on health effects posed by ingestion of mycotoxins-contaminated food and feed by humans and livestock, concerns have been raised towards providing more insights on screening of agri-food commodities to benefit consumers. Available reports indicate majority of edible oil-yielding seeds to be contaminated by various fungi, capable of producing mycotoxins. These mycotoxins can enter human food chain via use of edible oils or via animals fed with contaminated oil cake residues. In this review, we have decisively evaluated available data (from the past decade) pertaining towards fungal occurrence and level of mycotoxins in various oil seeds and their edible oils. This review can be of practical use to justify the prevailing gaps, especially relevant to the research on presence of mycotoxins in edible plant based oils. Copyright © 2016 Elsevier Ltd. All rights reserved.

A Graph Summarization Algorithm Based on RFID Logistics

NASA Astrophysics Data System (ADS)

Sun, Yan; Hu, Kongfa; Lu, Zhipeng; Zhao, Li; Chen, Ling

Radio Frequency Identification (RFID) applications are set to play an essential role in object tracking and supply chain management systems. The volume of data generated by a typical RFID application will be enormous as each item will generate a complete history of all the individual locations that it occupied at every point in time. The movement trails of such RFID data form gigantic commodity flowgraph representing the locations and durations of the path stages traversed by each item. In this paper, we use graph to construct a warehouse of RFID commodity flows, and introduce a database-style operation to summarize graphs, which produces a summary graph by grouping nodes based on user-selected node attributes, further allows users to control the hierarchy of summaries. It can cut down the size of graphs, and provide convenience for users to study just on the shrunk graph which they interested. Through extensive experiments, we demonstrate the effectiveness and efficiency of the proposed method.

Virtual suturing simulation based on commodity physics engine for medical learning.

PubMed

Choi, Kup-Sze; Chan, Sze-Ho; Pang, Wai-Man

2012-06-01

Development of virtual-reality medical applications is usually a complicated and labour intensive task. This paper explores the feasibility of using commodity physics engine to develop a suturing simulator prototype for manual skills training in the fields of nursing and medicine, so as to enjoy the benefits of rapid development and hardware-accelerated computation. In the prototype, spring-connected boxes of finite dimension are used to simulate soft tissues, whereas needle and thread are modelled with chained segments. Spherical joints are used to simulate suture's flexibility and to facilitate thread cutting. An algorithm is developed to simulate needle insertion and thread advancement through the tissue. Two-handed manipulations and force feedback are enabled with two haptic devices. Experiments on the closure of a wound show that the prototype is able to simulate suturing procedures at interactive rates. The simulator is also used to study a curvature-adaptive suture modelling technique. Issues and limitations of the proposed approach and future development are discussed.

Structural analysis of N-linked carbohydrate chains of funnel web spider (Agelenopsis aperta) venom peptide isomerase.

PubMed

Shikata, Y; Ohe, H; Mano, N; Kuwada, M; Asakawa, N

1998-06-01

The structure of the N-linked carbohydrate chains of peptide isomerase from the venom of the funnel web spider (Agelenopsis aperta) has been analyzed. Carbohydrates were released from peptide isomerase by hydrazinolysis and reductively aminated with 2-aminopyridine. The fluorescent derivatives were purified by phenol/chloroform extraction, followed by size-exclusion HPLC. The structure of the purified pyridylamino (PA-) carbohydrate chains were analyzed by a combination of two-dimensional HPLC mapping, sugar composition analysis, sequential exoglycosidase digestions, and mass spectrometry. The peptide isomerase contains six kinds of N-linked carbohydrate chains of truncated high-mannose type, with a fucose alpha 1-6 linked to the reducing N-acetylglucosamine in approximately 80% of them.

Territorial Disputes in Spratly: An Assessment of the Philippine Initiatives

DTIC Science & Technology

2013-03-01

in this region.1 It is an area with hundreds of reefs , islets, rocks and shoals, with the majority located in the Spratly and Paracel chain of... reefs which are surrounded by rich fishing grounds and potentially contain gas and oil deposits. The chain of islands is wholly and partly claimed...shelf.7 Brunei declared its maritime boundary with Vietnam an Exclusive Economic Zone (EEZ) in 1984, thus, “asserting an implicit claim to Louisa Reef

Impact of vCJD on blood supply.

PubMed

Seitz, Rainer; von Auer, Friedger; Blümel, Johannes; Burger, Reinhard; Buschmann, Anne; Dietz, Klaus; Heiden, Margarethe; Hitzler, Walter E; Klamm, Horst; Kreil, Thomas; Kretzschmar, Hans; Nübling, Micha; Offergeld, Ruth; Pauli, Georg; Schottstedt, Volkmar; Volkers, Peter; Zerr, Inga

2007-04-01

Variant Creutzfeldt-Jakob disease (vCJD) is an at present inevitably lethal neurodegenerative disease which can only be diagnosed definitely post mortem. The majority of the approximately 200 victims to date have resided in the UK where most contaminated beef materials entered the food chain. Three cases in the UK demonstrated that vCJD can be transmitted by blood transfusion. Since BSE and vCJD have spread to several countries outside the UK, it appears advisable that specific risk assessments be carried out in different countries and geographic areas. This review explains the approach adopted by Germany in assessing the risk and considering precautionary measures. A fundamental premise is that the feeding chain of cattle and the food chain have been successfully and permanently cleared from contaminated material. This raises the question of whether transmissions via blood transfusions could have the potential to perpetuate vCJD in mankind. A model calculation based on actual population data showed, however, that this would not be the case. Moreover, an exclusion of transfusion recipients from blood donation would add very little to the safety of blood transfusions, but would have a considerable impact on blood supply. Therefore, an exclusion of transfusion recipients was not recommended in Germany.

Vasotropic light-chain amyloidosis and ischaemic cholangiopathy.

PubMed

Johnston, Emma L; Wilkinson, Mark; Knisely, A S

2015-06-25

A 75-year-old woman was incidentally found to have deranged liver function tests (LFTs). She was well, apart from 2 years of dyspnoea. Investigations had revealed atrial fibrillation and a right pleural effusion, without identified aetiology. On examination, the only finding was a palpable liver edge. Initial blood and ultrasound screening suggested no cause. The patient underwent liver biopsy. Microscopy showed κ-immunoglobulin light chains deposited exclusively in portal tracts, within blood vessel and bile duct walls. This pattern, although unusual, raised the possibility of κ-light chain disease. Serum electrophoresis was normal, as were serum immunoglobulin values. Serum concentrations of κ-light chains were elevated and microscopy of aspirated bone marrow found light-chain deposits with 10% plasmacytosis. Serum amyloid P (SAP) scintigraphy demonstrated splenic uptake. Myeloma, κ-light chain, with light-chain amyloidosis was diagnosed. The patient has responded well to cyclophosphamide, bortazomib and dexamethasone chemotherapy, and her LFTs are now nearly normal. 2015 BMJ Publishing Group Ltd.

Application of Bayesian techniques to model the burden of human salmonellosis attributable to U.S. food commodities at the point of processing: adaptation of a Danish model.

PubMed

Guo, Chuanfa; Hoekstra, Robert M; Schroeder, Carl M; Pires, Sara Monteiro; Ong, Kanyin Liane; Hartnett, Emma; Naugle, Alecia; Harman, Jane; Bennett, Patricia; Cieslak, Paul; Scallan, Elaine; Rose, Bonnie; Holt, Kristin G; Kissler, Bonnie; Mbandi, Evelyne; Roodsari, Reza; Angulo, Frederick J; Cole, Dana

2011-04-01

Mathematical models that estimate the proportion of foodborne illnesses attributable to food commodities at specific points in the food chain may be useful to risk managers and policy makers to formulate public health goals, prioritize interventions, and document the effectiveness of mitigations aimed at reducing illness. Using human surveillance data on laboratory-confirmed Salmonella infections from the Centers for Disease Control and Prevention and Salmonella testing data from U.S. Department of Agriculture Food Safety and Inspection Service's regulatory programs, we developed a point-of-processing foodborne illness attribution model by adapting the Hald Salmonella Bayesian source attribution model. Key model outputs include estimates of the relative proportions of domestically acquired sporadic human Salmonella infections resulting from contamination of raw meat, poultry, and egg products processed in the United States from 1998 through 2003. The current model estimates the relative contribution of chicken (48%), ground beef (28%), turkey (17%), egg products (6%), intact beef (1%), and pork (<1%) across 109 Salmonella serotypes found in food commodities at point of processing. While interpretation of the attribution estimates is constrained by data inputs, the adapted model shows promise and may serve as a basis for a common approach to attribution of human salmonellosis and food safety decision-making in more than one country. © Mary Ann Liebert, Inc.

Application of Bayesian Techniques to Model the Burden of Human Salmonellosis Attributable to U.S. Food Commodities at the Point of Processing: Adaptation of a Danish Model

PubMed Central

Guo, Chuanfa; Hoekstra, Robert M.; Schroeder, Carl M.; Pires, Sara Monteiro; Ong, Kanyin Liane; Hartnett, Emma; Naugle, Alecia; Harman, Jane; Bennett, Patricia; Cieslak, Paul; Scallan, Elaine; Rose, Bonnie; Holt, Kristin G.; Kissler, Bonnie; Mbandi, Evelyne; Roodsari, Reza; Angulo, Frederick J.

2011-01-01

Abstract Mathematical models that estimate the proportion of foodborne illnesses attributable to food commodities at specific points in the food chain may be useful to risk managers and policy makers to formulate public health goals, prioritize interventions, and document the effectiveness of mitigations aimed at reducing illness. Using human surveillance data on laboratory-confirmed Salmonella infections from the Centers for Disease Control and Prevention and Salmonella testing data from U.S. Department of Agriculture Food Safety and Inspection Service's regulatory programs, we developed a point-of-processing foodborne illness attribution model by adapting the Hald Salmonella Bayesian source attribution model. Key model outputs include estimates of the relative proportions of domestically acquired sporadic human Salmonella infections resulting from contamination of raw meat, poultry, and egg products processed in the United States from 1998 through 2003. The current model estimates the relative contribution of chicken (48%), ground beef (28%), turkey (17%), egg products (6%), intact beef (1%), and pork (<1%) across 109 Salmonella serotypes found in food commodities at point of processing. While interpretation of the attribution estimates is constrained by data inputs, the adapted model shows promise and may serve as a basis for a common approach to attribution of human salmonellosis and food safety decision-making in more than one country. PMID:21235394

Evaluating opportunities to improve material and energy impacts in commodity supply chains

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanes, Rebecca J.; Carpenter, Alberta

When evaluated at the scale of individual processes, next-generation technologies may be more energy and emissions intensive than current technology. Furthermore, many advanced technologies have the potential to reduce material and energy consumption in upstream or downstream processing stages. In order to fully understand the benefits and consequences of technology deployment, next-generation technologies should be evaluated in context, as part of a supply chain. This work presents the Materials Flow through Industry (MFI) supply chain modeling tool. The MFI tool is a cradle-to-gate linear network model of the US industrial sector that can model a wide range of manufacturing scenarios,more » including changes in production technology and increases in industrial energy efficiency. The MFI tool was developed to perform supply chain scale analyses in order to quantify the impacts and benefits of next-generation technologies and materials at that scale. For the analysis presented in this paper, the MFI tool is utilized to explore a case study comparing three lightweight vehicle supply chains to the supply chain of a conventional, standard weight vehicle. Several of the lightweight vehicle supply chains are evaluated under manufacturing scenarios that include next-generation production technologies and next-generation materials. Results indicate that producing lightweight vehicles is more energy and emission intensive than producing the non-lightweight vehicle, but the fuel saved during vehicle use offsets this increase. In this case study, greater reductions in supply chain energy and emissions were achieved through the application of the next-generation technologies than from application of energy efficiency increases.« less

Evaluating opportunities to improve material and energy impacts in commodity supply chains

DOE PAGES

Hanes, Rebecca J.; Carpenter, Alberta

2017-01-10

When evaluated at the scale of individual processes, next-generation technologies may be more energy and emissions intensive than current technology. Furthermore, many advanced technologies have the potential to reduce material and energy consumption in upstream or downstream processing stages. In order to fully understand the benefits and consequences of technology deployment, next-generation technologies should be evaluated in context, as part of a supply chain. This work presents the Materials Flow through Industry (MFI) supply chain modeling tool. The MFI tool is a cradle-to-gate linear network model of the US industrial sector that can model a wide range of manufacturing scenarios,more » including changes in production technology and increases in industrial energy efficiency. The MFI tool was developed to perform supply chain scale analyses in order to quantify the impacts and benefits of next-generation technologies and materials at that scale. For the analysis presented in this paper, the MFI tool is utilized to explore a case study comparing three lightweight vehicle supply chains to the supply chain of a conventional, standard weight vehicle. Several of the lightweight vehicle supply chains are evaluated under manufacturing scenarios that include next-generation production technologies and next-generation materials. Results indicate that producing lightweight vehicles is more energy and emission intensive than producing the non-lightweight vehicle, but the fuel saved during vehicle use offsets this increase. In this case study, greater reductions in supply chain energy and emissions were achieved through the application of the next-generation technologies than from application of energy efficiency increases.« less

A Study of Shared-Memory Mutual Exclusion Protocols Using CADP

NASA Astrophysics Data System (ADS)

Mateescu, Radu; Serwe, Wendelin

Mutual exclusion protocols are an essential building block of concurrent systems: indeed, such a protocol is required whenever a shared resource has to be protected against concurrent non-atomic accesses. Hence, many variants of mutual exclusion protocols exist in the shared-memory setting, such as Peterson's or Dekker's well-known protocols. Although the functional correctness of these protocols has been studied extensively, relatively little attention has been paid to their non-functional aspects, such as their performance in the long run. In this paper, we report on experiments with the performance evaluation of mutual exclusion protocols using Interactive Markov Chains. Steady-state analysis provides an additional criterion for comparing protocols, which complements the verification of their functional properties. We also carefully re-examined the functional properties, whose accurate formulation as temporal logic formulas in the action-based setting turns out to be quite involved.

Identification of co-infection by rotavirus and parvovirus in dogs with gastroenteritis in Mexico.

PubMed

Ortega, Ariadna Flores; Martínez-Castañeda, José Simón; Bautista-Gómez, Linda G; Muñoz, Raúl Fajardo; Hernández, Israel Quijano

This is the first report on circulating canine rotavirus in Mexico. Fifty samples from dogs with gastroenteritis were analyzed used polymerase chain reaction and reverse transcription polymerase chain reaction in order to identify parvovirus and rotavirus, respectively; 7% of dogs were infected with rotavirus exclusively, while 14% were co-infected with both rotavirus and parvovirus; clinical signs in co-infected dogs were more severe. Copyright © 2017 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

Beyond fossil fuel-driven nitrogen transformations.

PubMed

Chen, Jingguang G; Crooks, Richard M; Seefeldt, Lance C; Bren, Kara L; Bullock, R Morris; Darensbourg, Marcetta Y; Holland, Patrick L; Hoffman, Brian; Janik, Michael J; Jones, Anne K; Kanatzidis, Mercouri G; King, Paul; Lancaster, Kyle M; Lymar, Sergei V; Pfromm, Peter; Schneider, William F; Schrock, Richard R

2018-05-25

Nitrogen is fundamental to all of life and many industrial processes. The interchange of nitrogen oxidation states in the industrial production of ammonia, nitric acid, and other commodity chemicals is largely powered by fossil fuels. A key goal of contemporary research in the field of nitrogen chemistry is to minimize the use of fossil fuels by developing more efficient heterogeneous, homogeneous, photo-, and electrocatalytic processes or by adapting the enzymatic processes underlying the natural nitrogen cycle. These approaches, as well as the challenges involved, are discussed in this Review. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells.

PubMed

van Roeyen, C R C; Ostendorf, T; Denecke, B; Bokemeyer, D; Behrmann, I; Strutz, F; Lichenstein, H S; LaRochelle, W J; Pena, C E; Chaudhuri, A; Floege, J

2006-04-01

Platelet-derived growth factor (PDGF)-BB and PDGF-DD mediate mesangial cell proliferation in vitro and in vivo. While PDGF-BB is a ligand for the PDGF alpha- and beta-receptor chains, PDGF-DD binds more selectively to the beta-chain, suggesting potential differences in the biological activities. Signal transduction and regulation of gene expression induced by PDGF-BB and -DD were compared in primary human mesangial cells (HMCs), which expressed PDGF alpha- and beta-receptor subunits. The growth factor concentrations used were chosen based on their equipotency in inducing HMCs proliferation and binding to the betabeta-receptor. Both growth factors, albeit at different concentrations induced phosphorylation and activation of extracellular signal-regulated kinase 1 (ERK1) and ERK2. In addition, PDGFs led to the phosphorylation and activation of signal transducers and activators of transcription 1 (STAT1) and STAT3. HMCs proliferation induced by either PDGF-BB or -DD could be blocked by signal transduction inhibitors of the mitogen-activated protein kinase-, Janus kinase (JAK)/STAT-, or phosphatidyl-inositol 3-kinase pathways. Using a gene chip array and subsequent verification by real-time reverse transcriptase (RT)-polymerase chain reaction, we found that in HMC genes for matrix metalloproteinase 13 (MMP-13) and MMP-14 and, to a low extent, cytochrome B5 and cathepsin L were exclusively regulated by PDGF-BB, whereas no exclusive gene regulation was detected by PDGF-DD. However, at the protein level, both MMP-13 and -14 were equally induced by PDGF-BB and -DD. PDGF-BB and -DD effect similar biological responses in HMCs albeit at different potencies. Rare apparently differential gene regulation did not result in different protein expression, suggesting that in HMCs both PDGFs exert their biological activity almost exclusively via the PDGF beta-receptor.

V(D)J recombination and allelic exclusion of a TCR beta-chain minilocus occurs in the absence of a functional promoter.

PubMed

Alvarez, J D; Anderson, S J; Loh, D Y

1995-08-01

Transcriptional activation of rearranging Ag receptor gene segments has been hypothesized to regulate their accessibility to V(D)J recombination. We analyzed the role of a functional promoter in the rearrangement of the murine TCR beta-chain locus using two transgenic minilocus constructs. These miniloci each contain an unrearranged V beta 8.3 gene. One has a wild-type V beta 8.3 gene, but the other has a V beta 8.3 gene with a promoter mutation that was previously shown to abrogate transcription in tissue culture. FACS analysis of thymus and lymph node cells from transgenic mouse lines showed that only the lines with the wild-type V beta 8.3 gene promoter express an 8.3 TCR beta-chain. Consistent with the protein expression data, V beta 8.3 gene transcripts were found only in the transgenic lines with the wild-type promoter. Using a quantitative PCR-based assay, it was shown that both types of transgenic lines recombine the V beta 8.3 gene at similar levels. Rearrangement of the transgenes was normal with respect to thymic development and junctional reading frame. Interestingly, both types of miniloci also underwent allelic exclusion in that recombination was blocked by the expression of a rearranged TCR beta-chain transgene. We conclude that a functional V beta gene promoter is not necessary for proper V(D)J recombination to occur.

Designing and Creating a Synthetic Omega Oxidation Pathway in Saccharomyces cerevisiae Enables Production of Medium-Chain α, ω-Dicarboxylic Acids

PubMed Central

Han, Li; Peng, Yanfeng; Zhang, Yuangyuan; Chen, Wujiu; Lin, Yuping; Wang, Qinhong

2017-01-01

Medium-chain (C8–C14) α, ω-dicarboxylic acids (α, ω-DCAs), which have numerous applications as raw materials for producing various commodities and polymers in chemical industry, are mainly produced from chemical or microbial conversion of petroleum-derived alkanes or plant-derived fatty acids at present. Recently, significant attention has been gained to microbial production of medium-chain α, ω-DCAs from simple renewable sugars. Here, we designed and created a synthetic omega oxidation pathway in Saccharomyces cerevisiae to produce C10 and C12 α, ω-DCAs from renewable sugars and fatty acids by introducing a heterogeneous cytochrome P450 CYP94C1 and cytochrome reductase ATR1. Furthermore, the deletion of fatty acyl-CoA synthetase genes FAA1 and FAA4 increased the production of medium-chain α, ω-DCAs from 4.690 ± 0.088 mg/L to 12.177 ± 0.420 mg/L and enabled the production of C14 and C16 α, ω-DCAs at low percentage. But blocking β-oxidation pathway by deleting fatty-acyl coenzyme A oxidase gene POX1 and overexpressing different thioesterase genes had no significant impact on the production and the composition of α, ω-dicarboxylic acids. Overall, our study indicated the potential of microbial production of medium-chain α, ω-DCAs from renewable feedstocks using engineered yeast. PMID:29163455

Effects of sugars on lipid bilayers during dehydration--SAXS/WAXS measurements and quantitative model.

PubMed

Lenné, Thomas; Garvey, Christopher J; Koster, Karen L; Bryant, Gary

2009-02-26

We present an X-ray scattering study of the effects of dehydration on the bilayer and chain-chain repeat spacings of dipalmitoylphosphatidylcholine bilayers in the presence of sugars. The presence of sugars has no effect on the average spacing between the phospholipid chains in either the fluid or gel phase. Using this finding, we establish that for low sugar concentrations only a small amount of sugar exclusion occurs. Under these conditions, the effects of sugars on the membrane transition temperatures can be explained quantitatively by the reduction in hydration repulsion between bilayers due to the presence of the sugars. Specific bonding of sugars to lipid headgroups is not required to explain this effect.

MOELCULAR SIZE EXCLUSION BY SOIL ORGANIC MATERIALS ESTIMATED FROM THEIR SWELLING IN ORGANIC SOLVENTS

EPA Science Inventory

A published method previously developed to measure the swelling characteristics of pow dered coal samples has been adapted for swelling measurements on various peat, pollen, chain, and cellulose samples The swelling of these macromolecular materials is the volumetric manifestatio...

The effect of structured triglycerides on the kinetic stability of total nutrient admixtures.

PubMed

Balogh, Judit; Bubenik, Júlia; Dredán, Judit; Csempesz, Ferenc; Kiss, Dorottya; Zelkó, Romána

2005-10-05

The physical stability of two types of total parenteral nutrient (TPN) admixtures was studied as a function of storage time and temperature. One of them contained only structured triglycerides and the other exclusively long-chain triglycerides as lipid components. Droplet size of the mixtures was followed by photon correlation spectroscopy for 10 days. Zeta potential and dynamic surface tension measurements were carried out to evaluate the possible changes in the charge and interfacial surface tension of the emulsion droplets during the storage. pH values were monitored in order to follow the possible decomposition processes in the course of storage. Droplet size of emulsions prepared with lipids containing exclusively long-chain triglycerides showed remarkable increase after 4 days of storage in contrast with that of the mixtures containing structured lipids. The obtained results indicate that besides the advantageous metabolic effects of structured triglycerides, their application is recommended to improve the physical stability of TPN admixtures.

Evaluating Opportunities to Improve Material and Energy Impacts in Commodity Supply Chains.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hanes, Rebecca J.; Carpenter, Alberta

When evaluated at the process level, next-generation technologies may be more energy and emissions intensive than current technology. However, many advanced technologies have the potential to reduce material and energy consumption in upstream or downstream processing stages. In order to fully understand the benefits and consequences of technology deployment, next-generation technologies should be evaluated in context, as part of a supply chain. This work presents the Material Flows through Industry (MFI) scenario modeling tool. The MFI tool is a cradle-to-gate linear network model of the U.S. industrial sector that can model a wide range of manufacturing scenarios, including changes inmore » production technology, increases in industrial energy efficiency, and substitution between functionally equivalent materials. The MFI tool was developed to perform supply chain scale analyses in order to quantify the impacts and benefits of next-generation technologies and materials at that scale. For the analysis presented in this paper, the MFI tool is utilized to explore a case study comparing a steel supply chain to the supply chains of several functionally equivalent materials. Several of the alternatives to the baseline steel supply chain include next-generation production technologies and materials. Results of the case study show that aluminum production scenarios can out-perform the steel supply chain by using either an advanced smelting technology or an increased aluminum recycling rate. The next-generation material supply chains do not perform as well as either aluminum or steel, but may offer additional use phase reductions in energy and emissions that are outside the scope of the MFI tool. Future work will combine results from the MFI tool with a use phase analysis.« less

Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin.

PubMed

Tynan, S H; Purohit, A; Doxsey, S J; Vallee, R B

2000-10-20

The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species separable by two-dimensional electrophoresis and which we have proposed to represent at least two gene products. Recently, we demonstrated the first known function for the LICs: binding to the centrosomal protein, pericentrin, which represents a novel, non-dynactin-based cargo-binding mechanism. Here we report the cloning of rat LIC1, which is approximately 75% homologous to rat LIC2 and also contains a P-loop consensus sequence. We compared LIC1 and LIC2 for the ability to interact with pericentrin, and found that only LIC1 will bind. A functional P-loop sequence is not required for this interaction. We have mapped the interaction to the central region of both LIC1 and pericentrin. Using recombinant LICs, we found that they form homooligomers, but not heterooligomers, and exhibit mutually exclusive binding to the heavy chain. Additionally, overexpressed pericentrin is seen to interact with endogenous LIC1 exclusively. Together these results demonstrate the existence of two subclasses of cytoplasmic dynein: LIC1-containing dynein, and LIC2-containing dynein, only the former of which is involved in pericentrin association with dynein.

Polymerase chain reaction technology as analytical tool in agricultural biotechnology.

PubMed

Lipp, Markus; Shillito, Raymond; Giroux, Randal; Spiegelhalter, Frank; Charlton, Stacy; Pinero, David; Song, Ping

2005-01-01

The agricultural biotechnology industry applies polymerase chain reaction (PCR) technology at numerous points in product development. Commodity and food companies as well as third-party diagnostic testing companies also rely on PCR technology for a number of purposes. The primary use of the technology is to verify the presence or absence of genetically modified (GM) material in a product or to quantify the amount of GM material present in a product. This article describes the fundamental elements of PCR analysis and its application to the testing of grains. The document highlights the many areas to which attention must be paid in order to produce reliable test results. These include sample preparation, method validation, choice of appropriate reference materials, and biological and instrumental sources of error. The article also discusses issues related to the analysis of different matrixes and the effect they may have on the accuracy of the PCR analytical results.

Changes in the carbon footprint of Japanese households in an aging society.

PubMed

Shigetomi, Yosuke; Nansai, Keisuke; Kagawa, Shigemi; Tohno, Susumu

2014-06-03

As the aging and low birthrate trends continue in Japan, and as changes in the working population and consumption patterns occur, new factors are expected to have an impact on consumption-based greenhouse gas (GHG) emissions. We present the impacts of changes in the composition of Japanese households on GHG emission structures using current (2005) consumption-based accounting on the commodity sectors that are expected to require priority efforts for reducing emissions in 2035. This is done using the Global Link Input-Output model (GLIO) and domestic household consumption data and assuming that recent detailed consumption expenditures based on the Social Accounting Matrix (SAM) will continue into the future. The results show that consumption-based GHG emissions derived from Japanese household consumption in 2035 are estimated to be 1061 Mt-CO2eq (4.2% lower than in 2005). This study can be used to reveal more information and as a resource in developing policies to more meticulously and efficiently reduce emissions based on emission and import rates for each domestic and overseas commodity supply chain.

Hole hopping through tyrosine/tryptophan chains protects proteins from oxidative damage

PubMed Central

Gray, Harry B.; Winkler, Jay R.

2015-01-01

Living organisms have adapted to atmospheric dioxygen by exploiting its oxidizing power while protecting themselves against toxic side effects. Reactive oxygen and nitrogen species formed during oxidative stress, as well as high-potential reactive intermediates formed during enzymatic catalysis, could rapidly and irreversibly damage polypeptides were protective mechanisms not available. Chains of redox-active tyrosine and tryptophan residues can transport potentially damaging oxidizing equivalents (holes) away from fragile active sites and toward protein surfaces where they can be scavenged by cellular reductants. Precise positioning of these chains is required to provide effective protection without inhibiting normal function. A search of the structural database reveals that about one third of all proteins contain Tyr/Trp chains composed of three or more residues. Although these chains are distributed among all enzyme classes, they appear with greatest frequency in the oxidoreductases and hydrolases. Consistent with a redox-protective role, approximately half of the dioxygen-using oxidoreductases have Tyr/Trp chain lengths ≥3 residues. Among the hydrolases, long Tyr/Trp chains appear almost exclusively in the glycoside hydrolases. These chains likely are important for substrate binding and positioning, but a secondary redox role also is a possibility. PMID:26195784

Supply chain management of health commodities for reducing global disease burden.

PubMed

Chukwu, Otuto Amarauche; Ezeanochikwa, Valentine Nnaemeka; Eya, Benedict Ejikeme

Reducing global disease burden requires improving access to medicines, thus the need for efficient and effective supply chain management for medicines. The Nigerian government came up with new policies on Mega Drug Distribution Centres and National Drug Distribution Guidelines to improve access to quality medicines with pharmacists having a key role to play. However, pharmacists in Nigeria seem not to be aware and adequately equipped to handle the medicines supply chain. This article aimed at assessing the awareness and readiness of Nigerian pharmacists on supply chain management practices for improving access to medicines. Pharmacists in Nigeria's Capital were randomly sampled. Semi-structured questionnaires were administered. Descriptive statistics was used in data analysis. P values less than 0.05 were considered to be significant. 29.3%, 20.7% and 53.7% were not aware of supply chain management, National Drug Distribution Guidelines and Mega Drug Distribution Centres, respectively. 85.46% do not have a copy of the National Drug Distribution Guidelines. 78% were not aware that Mega Drug Distribution Centres are already operational. 35.4% have never been involved in any supply chain management practice. 69.5% often experience stock out of vital and essential medicines, of which 85.2% were in hospitals. 15.9% were successful in managing their facility's supply chains. 84.1% opined that pharmacists in Nigeria are not yet ready to handle the medicines supply chain. Findings showed limited awareness and readiness on supply chain management of medicines. This may be due to inadequate supply chain management skills and infrastructure, poor financing, lack of accountability and poor management. Tackling these as well as pharmacists showing more interest in the country's health policies and obtaining necessary postgraduate certifications will lead to improvements. This will improve access to quality medicines and thus help in the fight to reduce disease burden both locally and globally. Copyright © 2016 Elsevier Inc. All rights reserved.

Rapid diagnostic test supply chain and consumption study in Cabo Delgado, Mozambique: estimating stock shortages and identifying drivers of stock-outs.

PubMed

Hasselback, Leah; Crawford, Jessica; Chaluco, Timoteo; Rajagopal, Sharanya; Prosser, Wendy; Watson, Noel

2014-08-02

Malaria rapid diagnostic tests (RDTs) are particularly useful in low-resource settings where follow-through on traditional laboratory diagnosis is challenging or lacking. The availability of these tests depends on supply chain processes within the distribution system. In Mozambique, stock-outs of malaria RDTs are fairly common at health facilities. A longitudinal cross-sectional study was conducted to evaluate drivers of stock shortages in the Cabo Delgado province. Data were collected from purposively sampled health facilities, using monthly cross-sectional surveys between October 2011 and May 2012. Estimates of lost consumption (consumption not met due to stock-outs) served as the primary quantitative indicator of stock shortages. This is a better measure of the magnitude of stock-outs than binary indicators that only measure frequency of stock-outs at a given facility. Using a case study based methodology, distribution system characteristics were qualitatively analysed to examine causes of stock-outs at the provincial, district and health centre levels. 15 health facilities were surveyed over 120 time points. Stock-out patterns varied by data source; average monthly proportions of 59%, 17% and 17% of health centres reported a stock-out on stock cards, laboratory and pharmacy forms, respectively. Estimates of lost consumption percentage were significantly high; ranging from 0% to 149%; with a weighted average of 78%. Each ten-unit increase in monthly-observed consumption was associated with a nine-unit increase in lost consumption percentage indicating that higher rates of stock-outs occurred at higher levels of observed consumption. Causes of stock-outs included inaccurate tracking of lost consumption, insufficient sophistication in inventory management and replenishment, and poor process compliance by facility workers, all arguably stemming from inadequate attention to the design and implementation of the distribution system. Substantially high levels of RDT stock-outs were found in Cabo Delgado. Study findings point to a supply chain with a commendable degree of sophistication. However, insufficient attention paid to system design and implementation resulted in deteriorating performance in areas of increased need. In such settings fast moving commodities like malaria RDTs can call attention to supply chain vulnerabilities, the findings from which can be used to address other slower moving health commodities.

Rapid diagnostic test supply chain and consumption study in Cabo Delgado, Mozambique: estimating stock shortages and identifying drivers of stock-outs

PubMed Central

2014-01-01

Background Malaria rapid diagnostic tests (RDTs) are particularly useful in low-resource settings where follow-through on traditional laboratory diagnosis is challenging or lacking. The availability of these tests depends on supply chain processes within the distribution system. In Mozambique, stock-outs of malaria RDTs are fairly common at health facilities. A longitudinal cross-sectional study was conducted to evaluate drivers of stock shortages in the Cabo Delgado province. Methods Data were collected from purposively sampled health facilities, using monthly cross-sectional surveys between October 2011 and May 2012. Estimates of lost consumption (consumption not met due to stock-outs) served as the primary quantitative indicator of stock shortages. This is a better measure of the magnitude of stock-outs than binary indicators that only measure frequency of stock-outs at a given facility. Using a case study based methodology, distribution system characteristics were qualitatively analysed to examine causes of stock-outs at the provincial, district and health centre levels. Results 15 health facilities were surveyed over 120 time points. Stock-out patterns varied by data source; average monthly proportions of 59%, 17% and 17% of health centres reported a stock-out on stock cards, laboratory and pharmacy forms, respectively. Estimates of lost consumption percentage were significantly high; ranging from 0% to 149%; with a weighted average of 78%. Each ten-unit increase in monthly-observed consumption was associated with a nine-unit increase in lost consumption percentage indicating that higher rates of stock-outs occurred at higher levels of observed consumption. Causes of stock-outs included inaccurate tracking of lost consumption, insufficient sophistication in inventory management and replenishment, and poor process compliance by facility workers, all arguably stemming from inadequate attention to the design and implementation of the distribution system. Conclusions Substantially high levels of RDT stock-outs were found in Cabo Delgado. Study findings point to a supply chain with a commendable degree of sophistication. However, insufficient attention paid to system design and implementation resulted in deteriorating performance in areas of increased need. In such settings fast moving commodities like malaria RDTs can call attention to supply chain vulnerabilities, the findings from which can be used to address other slower moving health commodities. PMID:25086645

Molecular insight into the counteraction of trehalose on urea-induced protein denaturation using molecular dynamics simulation.

PubMed

Zhang, Na; Liu, Fu-Feng; Dong, Xiao-Yan; Sun, Yan

2012-06-21

Considerable experimental evidence indicates that trehalose can counteract the denaturing effects of urea on proteins. However, its molecular mechanism remains unknown due to the limitations of current experimental techniques. Herein, molecular dynamics simulations were performed to investigate the counteracting effects of trehalose against urea-induced denaturation of chymotrypsin inhibitor 2. The simulations indicate that the protein unfolds in 8 mol/L urea, but at the same condition the protein retains its native structure in the ternary solution of 8 mol/L urea and 1 mol/L trehalose. It is confirmed that the preferential exclusion of trehalose from the protein surface is the origin of its counteracting effects. It is found that trehalose binds urea via hydrogen bonds, so urea molecules are also expelled from the protein surface along with the preferential exclusion of trehalose. The exclusion of urea from the protein surface leads to the alleviation of the Lennard-Jones interactions between urea and the hydrophobic side chains of the protein in the ternary solution. In contrast, the electrostatic interactions between urea and the protein change little in the presence of trehalose because the decrease in the electrostatic interactions between urea and the protein backbone is canceled by the increase in the electrostatic interactions between urea and the charged side chains of the protein. The results have provided molecular explanations for the counteraction of urea-induced protein denaturation by trehalose.

The I binding specificity of human VH 4-34 (VH 4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3.

PubMed

Li, Y; Spellerberg, M B; Stevenson, F K; Capra, J D; Potter, K N

1996-03-01

Essentially all cold agglutinins (CA) with red blood cell I/i specificity isolated from patients with CA disease stemming from lymphoproliferative disorders utilize the VH 4-34 (VH 4-21) gene segment. This near universality of the restricted use of a single gene segment is substantially greater than that demonstrated for other autoantibodies. The monoclonal antibody 9G4 exclusively binds VH 4-34 encoded antibodies and serves as a marker for the VH 4-34 gene segment. Previous studies form our laboratory localized the 9G4 reactive area to framework region 1 (FR1). In the present study, the relative roles of VH FR1, heavy (H) chain complementarity determining region 3 (CDRH 3) and the light (L) chain in I antigen binding were investigated. Mutants containing FR1 sequences from the other VH families, CDRH 3 exchanges, and combinatorial antibodies involving L chain interchanges were produced in the baculovirus system and tested in an I binding assay. The data indicate that FR1 of the VH 4-34 gene segment and the CDRH 3 are essential for the interaction between CA and the I antigen, with the CDRH 3 being fundamental in determining the fine specificity of antigen binding (I versus i). Mutants with substantially altered CDRH 1 and CDRH 2 regions bind I as long as the FR1 is VH 4-34 encoded and the CDRH 3 has a permissive sequence. Light chain swaps indicate that even though antigen binding is predominantly mediated by the H chain, the association with antigen can be abrogated by an incompatible L chain. The necessity for VH 4-34 FR1 explains the almost exclusive use of the VH 4-34 gene segment in cold agglutinins. We hypothesize that, as a general phenomenon, the H chain FR1 of many antibodies may be important in providing the contact required for the close association of antibody with antigen, while the CDRH 3 dictates the fine specificity and strenght of binding.

17 CFR 4.41 - Advertising by commodity pool operators, commodity trading advisors, and the principals thereof.

Code of Federal Regulations, 2010 CFR

2010-04-01

... operators, commodity trading advisors, and the principals thereof. 4.41 Section 4.41 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Advertising § 4.41 Advertising by commodity pool operators, commodity trading advisors, and the...

Characterization of amylose nanoparticles prepared via nanoprecipitation: Influence of chain length distribution.

PubMed

Chang, Yanjiao; Yang, Jingde; Ren, Lili; Zhou, Jiang

2018-08-15

The influence of chain length distribution of amylose on size and structure of the amylose nanoparticles (ANPs) prepared through nanoprecipitation was investigated. Amylose with different chain length distributions was obtained by β-amylase treating amylose paste for different times and measured by size exclusion chromatography (SEC) and fluorophore-assisted carbohydrate electrophoresis (FACE). ANPs prepared via precipitation were characterized by using dynamic light scattering (DLS), scanning electron microscopy (SEM) and X-ray diffraction (XRD). Results showed that the β-amylase treatments led to decrease in chain length of amylose, and it was the most important factor affecting size of ANPs. When hydrolysis degree of amylose was 52.8%, mean size of ANPs decreased from 206.4 nm to 102.7 nm. All the ANPs displayed a V-type crystalline structure and the effect of amylose chain length on crystallinity of the precipitated ANPs was negligible in the investigated range. Copyright © 2018 Elsevier Ltd. All rights reserved.

Asymmetric simple exclusion process on chains with a shortcut.

PubMed

Bunzarova, Nadezhda; Pesheva, Nina; Brankov, Jordan

2014-03-01

We consider the asymmetric simple exclusion process (TASEP) on an open network consisting of three consecutively coupled macroscopic chain segments with a shortcut between the tail of the first segment and the head of the third one. The model was introduced by Y.-M. Yuan et al. [J. Phys. A 40, 12351 (2007)] to describe directed motion of molecular motors along twisted filaments. We report here unexpected results which revise the previous findings in the case of maximum current through the network. Our theoretical analysis, based on the effective rates' approximation, shows that the second (shunted) segment can exist in both low- and high-density phases, as well as in the coexistence (shock) phase. Numerical simulations demonstrate that the last option takes place in finite-size networks with head and tail chains of equal length, provided the injection and ejection rates at their external ends are equal and greater than one-half. Then the local density distribution and the nearest-neighbor correlations in the middle chain correspond to a shock phase with completely delocalized domain wall. Upon moving the shortcut to the head or tail of the network, the density profile takes a shape typical of a high- or low-density phase, respectively. Surprisingly, the main quantitative parameters of that shock phase are governed by a positive root of a cubic equation, the coefficients of which linearly depend on the probability of choosing the shortcut. Alternatively, they can be expressed in a universal way through the shortcut current. The unexpected conclusion is that a shortcut in the bulk of a single lane may create traffic jams.

Adapting Poisson-Boltzmann to the self-consistent mean field theory: Application to protein side-chain modeling

NASA Astrophysics Data System (ADS)

Koehl, Patrice; Orland, Henri; Delarue, Marc

2011-08-01

We present an extension of the self-consistent mean field theory for protein side-chain modeling in which solvation effects are included based on the Poisson-Boltzmann (PB) theory. In this approach, the protein is represented with multiple copies of its side chains. Each copy is assigned a weight that is refined iteratively based on the mean field energy generated by the rest of the protein, until self-consistency is reached. At each cycle, the variational free energy of the multi-copy system is computed; this free energy includes the internal energy of the protein that accounts for vdW and electrostatics interactions and a solvation free energy term that is computed using the PB equation. The method converges in only a few cycles and takes only minutes of central processing unit time on a commodity personal computer. The predicted conformation of each residue is then set to be its copy with the highest weight after convergence. We have tested this method on a database of hundred highly refined NMR structures to circumvent the problems of crystal packing inherent to x-ray structures. The use of the PB-derived solvation free energy significantly improves prediction accuracy for surface side chains. For example, the prediction accuracies for χ1 for surface cysteine, serine, and threonine residues improve from 68%, 35%, and 43% to 80%, 53%, and 57%, respectively. A comparison with other side-chain prediction algorithms demonstrates that our approach is consistently better in predicting the conformations of exposed side chains.

The use of real-time polymerase chain reaction for rapid diagnosis of skeletal tuberculosis.

PubMed

Kobayashi, Naomi; Fraser, Thomas G; Bauer, Thomas W; Joyce, Michael J; Hall, Gerri S; Tuohy, Marion J; Procop, Gary W

2006-07-01

We identified Mycobacterium tuberculosis DNA using real-time polymerase chain reaction on a specimen from an osteolytic lesion of a femoral condyle, in which the frozen section demonstrated granulomas. The process was much more rapid than is possible with culture. The rapid detection of M tuberculosis and the concomitant exclusion of granulomatous disease caused by nontuberculous mycobacteria or systemic fungi are necessary to appropriately treat skeletal tuberculosis. The detection and identification of M tuberculosis by culture may require several weeks using traditional methods. The real-time polymerase chain reaction method used has been shown to be rapid and reliable, and is able to detect and differentiate both tuberculous and nontuberculous mycobacteria. Real-time polymerase chain reaction may become a diagnostic standard for the evaluation of clinical specimens for the presence of mycobacteria; this case demonstrates the potential utility of this assay for the rapid diagnosis of skeletal tuberculosis.

Exclusive Breastfeeding and Clinical Malaria Risk in 6-Month-Old Infants: A Cross-Sectional Study from Kinshasa, Democratic Republic of the Congo

PubMed Central

Brazeau, Nicholas F.; Tabala, Martine; Kiketa, Landry; Kayembe, Dyna; Chalachala, Jean Lambert; Kawende, Bienvenu; Lapika, Bruno; Meshnick, Steven R.; Yotebieng, Marcel

2016-01-01

The World Health Organization recommends exclusive breastfeeding (EBF) for the first 6 months of life. However, the effect of EBF on malaria risk remains unclear. In the present study, 137 EBF infants and 358 non-EBF infants from the Democratic Republic of the Congo were assessed for fever and malaria infections by polymerase chain reaction, at 6 months of age. EBF was associated with a reduced risk of clinical malaria (odds ratio = 0.13; 95% confidence interval = 0.00–0.80), suggesting a protective effect of EBF against malaria. PMID:27549632

Analysis of Nuclear Factor-κB (NF-κB) Essential Modulator (NEMO) Binding to Linear and Lysine-linked Ubiquitin Chains and Its Role in the Activation of NF-κB*

PubMed Central

Kensche, Tobias; Tokunaga, Fuminori; Ikeda, Fumiyo; Goto, Eiji; Iwai, Kazuhiro; Dikic, Ivan

2012-01-01

Nuclear factor-κB (NF-κB) essential modulator (NEMO), a component of the inhibitor of κB kinase (IKK) complex, controls NF-κB signaling by binding to ubiquitin chains. Structural studies of NEMO provided a rationale for the specific binding between the UBAN (ubiquitin binding in ABIN and NEMO) domain of NEMO and linear (Met-1-linked) di-ubiquitin chains. Full-length NEMO can also interact with Lys-11-, Lys-48-, and Lys-63-linked ubiquitin chains of varying length in cells. Here, we show that purified full-length NEMO binds preferentially to linear ubiquitin chains in competition with lysine-linked ubiquitin chains of defined length, including long Lys-63-linked deca-ubiquitins. Linear di-ubiquitins were sufficient to activate both the IKK complex in vitro and to trigger maximal NF-κB activation in cells. In TNFα-stimulated cells, NEMO chimeras engineered to bind exclusively to Lys-63-linked ubiquitin chains mediated partial NF-κB activation compared with cells expressing NEMO that binds to linear ubiquitin chains. We propose that NEMO functions as a high affinity receptor for linear ubiquitin chains and a low affinity receptor for long lysine-linked ubiquitin chains. This phenomenon could explain quantitatively distinct NF-κB activation patterns in response to numerous cell stimuli. PMID:22605335

Hydrodynamic Versus Size-Exclusion Chromatography Characterization of Alternan and Comparison to Off-Line MALS

USDA-ARS?s Scientific Manuscript database

Alternan is an ultra-high molar mass polysaccharide composed of two different types of glycosidic linkages and which also possesses long-chain branching. It has great potential in a number of areas, including as a possible domestic replacement for gum Arabic. The high molar mass and large size of ...

10 CFR 26.159 - Assuring specimen security, chain of custody, and preservation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... licensee testing facility has retained the specimen in Bottle B, the licensee testing facility shall... the licensee testing facility. (2) The following are exclusive grounds requiring the MRO to cancel the... or legal challenge until they are no longer needed. (j) The laboratory shall discard a valid specimen...

Basal Immunoglobulin Signaling Actively Maintains Developmental Stage in Immature B Cells

PubMed Central

Tze, Lina E; Schram, Brian R; Lam, Kong-Peng; Hogquist, Kristin A; Hippen, Keli L; Liu, Jiabin; Shinton, Susan A; Otipoby, Kevin L; Rodine, Peter R; Vegoe, Amanda L; Kraus, Manfred; Hardy, Richard R; Schlissel, Mark S; Rajewsky, Klaus

2005-01-01

In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B stage. A subsequent functional light chain (LC) rearrangement then results in the surface expression of IgM at the immature B cell stage. Here we show that interruption of basal IgM signaling in immature B cells, either by the inducible deletion of surface Ig via Cre-mediated excision or by incubating cells with the tyrosine kinase inhibitor herbimycin A or the phosphatidylinositol 3-kinase inhibitor wortmannin, led to a striking “back-differentiation” of cells to an earlier stage in B cell development, characterized by the expression of pro-B cell genes. Cells undergoing this reversal in development also showed evidence of new LC gene rearrangements, suggesting an important role for basal Ig signaling in the maintenance of LC allelic exclusion. These studies identify a previously unappreciated level of plasticity in the B cell developmental program, and have important implications for our understanding of central tolerance mechanisms. PMID:15752064

Molecular weight distribution characterization of hydrophobe-modified hydroxyethyl cellulose by size-exclusion chromatography.

PubMed

Li, Yongfu; Meunier, David M; Partain, Emmett M

2014-09-12

Size-exclusion chromatography (SEC) of hydrophobe-modified hydroxyethyl cellulose (HmHEC) is challenging because polymer chains are not isolated in solution due to association of hydrophobic groups and hydrophobic interaction with column packing materials. An approach to neutralize these hydrophobic interactions was developed by adding β-cyclodextrin (β-CD) to the aqueous eluent. SEC mass recovery, especially for the higher molecular weight chains, increased with increasing concentration of β-CD in the eluent. A β-CD concentration of 0.75wt% in the eluent was determined to be optimal for the HmHEC polymers studied. These conditions enabled precise determinations of apparent molecular weight distributions exhibiting less than 2% relative standard deviation in the measured weight-average molecular weight (MW) for five injections on three studied samples and showed no significant differences in MW determined on two different days. The developed technology was shown to be very robust for characterizing HmHEC having MW from 500kg/mol to 2000kg/mol, and it can be potentially applied to other hydrophobe-modified polymers. Copyright © 2014 Elsevier B.V. All rights reserved.

Enzymatic properties of the membrane-bound NADH oxidase system in the aerobic respiratory chain of Bacillus cereus.

PubMed

Kim, Man Suk; Kim, Young Jae

2004-11-30

Membranes prepared from Bacillus cereus KCTC 3674, grown aerobically on a complex medium, oxidized NADH exclusively, whereas deamino-NADH was little oxidized. The respiratory chain-linked NADH oxidase exhibited an apparent K(m) value of approximately 65 microM for NADH. The maximum activity of the NADH oxidase was obtained at about pH 8.5 in the presence of 0.1 M KCl (or NaCl). Respiratory chain inhibitor 2-heptyl-4-hydroxyquinoline-N-oxide (HQNO) inhibited the activity of the NADH oxidase by about 90% at a concentration of 40 microM. Interestingly, rotenone and capsaicin inhibited the activity of the NADH oxidase by about 60% at a concentration of 40 microM and the activity was also highly sensitive to Ag(+).

17 CFR 5.4 - Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors.

Code of Federal Regulations, 2013 CFR

2013-04-01

... this chapter to commodity pool operators and commodity trading advisors. 5.4 Section 5.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFF-EXCHANGE FOREIGN CURRENCY TRANSACTIONS § 5.4 Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors. Part 4 of...

17 CFR 5.4 - Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors.

Code of Federal Regulations, 2012 CFR

2012-04-01

... this chapter to commodity pool operators and commodity trading advisors. 5.4 Section 5.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFF-EXCHANGE FOREIGN CURRENCY TRANSACTIONS § 5.4 Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors. Part 4 of...

Proteome analysis of the cardiac and pericardial tissue of Biomphalaria tenagophila populations susceptible and resistant to Schistosoma mansoni infection.

PubMed

Jannotti-Passos, Liana K; Andrade, Hélida M; Caldeira, Roberta L; Romanha, Alvaro J; Murta, Silvane M F; Chapeaurouge, Donat A; Perales, Jonas; Coelho, Paulo Marcos Z; Carvalho, Omar S

2008-03-01

For a better comprehension of the parasite-host interaction, proteins expressed by the cardiac and pericardial tissues were compared between susceptible (Cabo Frio) and resistant (Taim) Biomphalaria tenagophila populations, challenged (c) and non-challenged (nc) with Schistosoma mansoni. Proteins were separated by two-dimensional gel electrophoresis (2DE) and stained with Coomassie blue. A total of 146 and 135 spots were observed in Cabo Frio (CFnc) and in Taim (Tnc) non-challenged populations, respectively, whereas 153 spots were detected in both Cabo Frio (CFc) and Taim (Tc) challenged populations. Regarding comparisons between CFnc and CFc, the numbers of exclusive spots obtained were one and nine, respectively, whereas Tnc yielded 17 and Tc eight exclusive spots. By comparing the total of spots in CF (nc+c) with T (nc+c) populations, we obtained: four exclusive spots for CFc; zero for CFnc; four for Tc and; one for Tnc. A quantitative comparison (reason>2.5) of the total spots of CF (nc+c) with T (nc+c) populations allowed us to distinguish five more intense spots for Tc, 14 for Tnc, 15 for CFnc and 11 for CFc. In the CFnc population, two proteins were identified: actin and ATP synthase alpha chain; in the CFc population, four proteins: actin, calmodulin, HSP70, and dehydrogenase; in the Tnc population, five proteins: matrilin, HSP70, actin, ATP synthase alpha chain and intermediate filament of the protein; and in the Tc population, three proteins: actin, alpha-S1 casein and ATP synthase alpha chain. Out of a total of 79 spots, only nine proteins were identified due to the low number of available nucleotide sequences in the GenBank. Nevertheless, knowing proteins regarded as differentially expressed is indispensable for hitherto unidentified genes implicated in B. tenagophila resistance and or susceptibility to S. mansoni infection.

17 CFR 4.13 - Exemption from registration as a commodity pool operator.

Code of Federal Regulations, 2011 CFR

2011-04-01

... a commodity pool operator. 4.13 Section 4.13 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS General Provisions, Definitions and Exemptions § 4.13 Exemption from registration as a commodity pool operator. This section is...

17 CFR 32.9 - Fraud in connection with commodity option transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Fraud in connection with commodity option transactions. 32.9 Section 32.9 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.9 Fraud in connection with commodity...

Perfluoroalkyl Acids (PFAAs) in Serum from 2-4-Month-Old Infants: Influence of Maternal Serum Concentration, Gestational Age, Breast-Feeding, and Contaminated Drinking Water.

PubMed

Gyllenhammar, Irina; Benskin, Jonathan P; Sandblom, Oskar; Berger, Urs; Ahrens, Lutz; Lignell, Sanna; Wiberg, Karin; Glynn, Anders

2018-06-19

Little is known about factors influencing infant perfluorinated alkyl acid (PFAA) concentrations. Associations between serum PFAA concentrations in 2-4-month-old infants ( n = 101) and determinants were investigated by multiple linear regression and general linear model analysis. In exclusively breast-fed infants, maternal serum PFAA concentrations 3 weeks after delivery explained 13% (perfluoroundecanoic acid, PFUnDA) to 73% (perfluorohexanesulfonate, PFHxS) of infant PFAA concentration variation. Median infant/maternal ratios decreased with increasing PFAA carbon chain length from 2.8 for perfluoroheptanoic acid and perfluorooctanoic acid (PFOA) to 0.53 for PFUnDA and from 1.2 to 0.69 for PFHxS and perfluorooctanesulfonate (PFOS). Infant PFOA, perfluorononanoic acid (PFNA), and PFOS levels increased 0.7-1.2% per day of gestational age. Bottle-fed infants had mean concentrations of PFAAs 2 times lower than and a mean percentage of branched (%br) PFOS isomers 1.3 times higher than those of exclusively breast-fed infants. PFOA, PFNA, and PFHxS levels increased 8-11% per week of exclusive breast-feeding. Infants living in an area receiving PFAA-contaminated drinking water had 3-fold higher mean perfluorobutanesulfonate (PFBS) and PFHxS concentrations and higher mean %br PFHxS. Prenatal PFAA exposure and postnatal PFAA exposure significantly contribute to infant PFAA serum concentrations, depending on PFAA carbon chain length. Moderately PFBS- and PFHxS-contaminated drinking water is an important indirect exposure source.

Asymmetric simple exclusion process on chains with a shortcut

NASA Astrophysics Data System (ADS)

Bunzarova, Nadezhda; Pesheva, Nina; Brankov, Jordan

2014-03-01

We consider the asymmetric simple exclusion process (TASEP) on an open network consisting of three consecutively coupled macroscopic chain segments with a shortcut between the tail of the first segment and the head of the third one. The model was introduced by Y.-M. Yuan et al. [J. Phys. A 40, 12351 (2007), 10.1088/1751-8113/40/41/006] to describe directed motion of molecular motors along twisted filaments. We report here unexpected results which revise the previous findings in the case of maximum current through the network. Our theoretical analysis, based on the effective rates' approximation, shows that the second (shunted) segment can exist in both low- and high-density phases, as well as in the coexistence (shock) phase. Numerical simulations demonstrate that the last option takes place in finite-size networks with head and tail chains of equal length, provided the injection and ejection rates at their external ends are equal and greater than one-half. Then the local density distribution and the nearest-neighbor correlations in the middle chain correspond to a shock phase with completely delocalized domain wall. Upon moving the shortcut to the head or tail of the network, the density profile takes a shape typical of a high- or low-density phase, respectively. Surprisingly, the main quantitative parameters of that shock phase are governed by a positive root of a cubic equation, the coefficients of which linearly depend on the probability of choosing the shortcut. Alternatively, they can be expressed in a universal way through the shortcut current. The unexpected conclusion is that a shortcut in the bulk of a single lane may create traffic jams.

In the Field Feasibility of a Simple Method to Check for Radioactivity in Commodities and in the Environment

PubMed Central

Alessandri, Stefano

2017-01-01

Introduction: Some release of radionuclides into the environment can be expected from the growing number of nuclear plants, either in or out of service. The citizen and the big organization could be both interested in simple and innovative methods for checking the radiological safety of their environment and of commodities, starting from foods. Methods: In this work three methods to detect radioactivity are briefly compared  focusing on the most recent, which converts a smartphone into a radiation counter. Results: The results of a simple sensitivity test are presented showing the measure of the activity of reference sources put at different distances from each sensor. Discussion: The three methods are discussed in terms of availability, technology, sensitivity, resolution and usefulness. The reported results can be usefully transferred into a radiological emergency scenario and they also offer some interesting implication for our current everyday life, but show that the hardware of the tested smart-phone can detect only high levels of radioactivity. However the technology could be interesting to build a working detection and measurement chain which could start from a diffused and networked first screening before the final high resolution analysis. PMID:28744409

Human health problems associated with current agricultural food production.

PubMed

Bhat, Ramesh V

2008-01-01

Scientific and technological developments in the agricultural sectors in the recent past has resulted in increased food production and at the same time led to certain public health concerns. Unseasonal rains at the time of harvest and improper post harvest technology often results in agricultural commodities being contaminated with certain fungi and results in the production of mycotoxins. Consumption of such commodities has resulted in human disease outbreaks. Naturally occurring toxins, inherently present in foods and either consumed as such or mixed up with grains, had been responsible for disease outbreaks. Other possible causes of health concern include the application of various agrochemicals such as pesticides and the use of antibiotics in aquaculture and veterinary practices. Foodborne pathogens entering the food chain during both traditional and organic agriculture pose a challenge to public health. Modern biotechnology, producing genetically modified foods, if not regulated appropriately could pose dangers to human health. Use of various integrated food management systems like the Hazard Analysis and critical control system approach for risk prevention, monitoring and control of food hazards are being emphasized with globalization to minimise the danger posed to human health from improper agricultural practices.

An Overview of Process Monitoring Related to the Production of Uranium Ore Concentrate

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGinnis, Brent

2014-04-01

Uranium ore concentrate (UOC) in various chemical forms, is a high-value commodity in the commercial nuclear market, is a potential target for illicit acquisition, by both State and non-State actors. With the global expansion of uranium production capacity, control of UOC is emerging as a potentially weak link in the nuclear supply chain. Its protection, control and management thus pose a key challenge for the international community, including States, regulatory authorities and industry. This report evaluates current process monitoring practice and makes recommendations for utilization of existing or new techniques for managing the inventory and tracking this material.

Upgrading Supply Chain Management Systems to Improve Availability of Medicines in Tanzania: Evaluation of Performance and Cost Effects.

PubMed

Mwencha, Marasi; Rosen, James E; Spisak, Cary; Watson, Noel; Kisoka, Noela; Mberesero, Happiness

2017-09-27

To address challenges in public health supply chain performance, Tanzania invested in a national logistics management unit (LMU) and a national electronic logistics management information system (eLMIS). This evaluation examined the impact of those 2 key management upgrades approximately 1 year after they were introduced. We used a nonexperimental pre-post study design to compare the previous system with the upgraded management system. We collected baseline data from August to November 2013. We conducted round 1 of post-implementation data collection during April and May 2015, about 1 year after implementation of the upgrades. We evaluated key indicators of data use and reporting; supply chain management practices such as storage and supervision; supply chain performance including stock-out and expiry rates; and supply chain cost and savings. We analyzed the data using a range of techniques including statistical testing of baseline and round-1 results, and cost, cost-effectiveness, and return on investment analysis. The upgrades were associated with improvements in data use, accessibility, visibility, and transparency; planning, control, and monitoring; support for quantification; stock-out rates; stock-out duration; commodity expiry; and forecast error. The upgraded system was more costly, but it was also more efficient, particularly when adjusting for the performance improvements. The upgrades also generated substantial savings that defrayed some, but not all, of the investment costs. Upgrades to Tanzania's supply chain management systems created multiple and complex pathways to impact. One year after implementation, the LMU and eLMIS brought about performance improvements through better data use and through improvements in some, but not all, management practices. Furthermore, the upgrades-while not inexpensive-contributed to greater system efficiency and modest savings. © Mwencha et al.

Upgrading Supply Chain Management Systems to Improve Availability of Medicines in Tanzania: Evaluation of Performance and Cost Effects

PubMed Central

Mwencha, Marasi; Rosen, James E; Spisak, Cary; Watson, Noel; Kisoka, Noela; Mberesero, Happiness

2017-01-01

ABSTRACT Background: To address challenges in public health supply chain performance, Tanzania invested in a national logistics management unit (LMU) and a national electronic logistics management information system (eLMIS). This evaluation examined the impact of those 2 key management upgrades approximately 1 year after they were introduced. Methods: We used a nonexperimental pre-post study design to compare the previous system with the upgraded management system. We collected baseline data from August to November 2013. We conducted round 1 of post-implementation data collection during April and May 2015, about 1 year after implementation of the upgrades. We evaluated key indicators of data use and reporting; supply chain management practices such as storage and supervision; supply chain performance including stock-out and expiry rates; and supply chain cost and savings. We analyzed the data using a range of techniques including statistical testing of baseline and round-1 results, and cost, cost-effectiveness, and return on investment analysis. Results: The upgrades were associated with improvements in data use, accessibility, visibility, and transparency; planning, control, and monitoring; support for quantification; stock-out rates; stock-out duration; commodity expiry; and forecast error. The upgraded system was more costly, but it was also more efficient, particularly when adjusting for the performance improvements. The upgrades also generated substantial savings that defrayed some, but not all, of the investment costs. Conclusion: Upgrades to Tanzania's supply chain management systems created multiple and complex pathways to impact. One year after implementation, the LMU and eLMIS brought about performance improvements through better data use and through improvements in some, but not all, management practices. Furthermore, the upgrades—while not inexpensive—contributed to greater system efficiency and modest savings. PMID:28877933

The Principles and the Specifics of Trading in Commodities

NASA Astrophysics Data System (ADS)

Baran, Dušan; Herbacsková, Anita

2012-12-01

In the present period of instability on financial markets, investments in commodities are the solution for elimination of the consequences of inflation and ensure the yield. When investing in commodities, the use of specifics of commodities compared to other assets. The distribution of commodities we can interpret for agricultural commodities, commodities of energy, precious and other metals, and weather. Therefore, in the framework of the investment portfolio are the commodities. This is the reason why one of the most popular types of investment assets now become commodities. In the interpretation of particular commodities we talk about commodity futures. The reason is that the spot market with commodities is limited storage facilities. The growth of the popularity, which allows a wide range of commodities, has caused that in addition to from institutional investors and speculators for trade may involve even small investors. This development will be supplemented by interpretation of the charts and figers, which will be commented and used for generalization of knowledge. Finally, the article will be interpreted by the further development of the market for commodities as it by article assumes from the results of research.

33 CFR 3.70-10 - Sector Honolulu Marine Inspection Zone and Captain of the Port Zone.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., including all the islands and atolls of the Hawaiian chain and the adjacent waters of the exclusive economic zone (EEZ); and the following islands and their adjacent waters of the EEZ: American Samoa, Johnston Atoll, Palmyra Atoll, Kingman Reef, Wake Island, Jarvis Island, Howland and Baker Islands, and Midway...

33 CFR 3.70-10 - Sector Honolulu Marine Inspection Zone and Captain of the Port Zone.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., including all the islands and atolls of the Hawaiian chain and the adjacent waters of the exclusive economic zone (EEZ); and the following islands and their adjacent waters of the EEZ: American Samoa, Johnston Atoll, Palmyra Atoll, Kingman Reef, Wake Island, Jarvis Island, Howland and Baker Islands, and Midway...

33 CFR 3.70-10 - Sector Honolulu Marine Inspection Zone and Captain of the Port Zone.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., including all the islands and atolls of the Hawaiian chain and the adjacent waters of the exclusive economic zone (EEZ); and the following islands and their adjacent waters of the EEZ: American Samoa, Johnston Atoll, Palmyra Atoll, Kingman Reef, Wake Island, Jarvis Island, Howland and Baker Islands, and Midway...

33 CFR 3.70-10 - Sector Honolulu Marine Inspection Zone and Captain of the Port Zone.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., including all the islands and atolls of the Hawaiian chain and the adjacent waters of the exclusive economic zone (EEZ); and the following islands and their adjacent waters of the EEZ: American Samoa, Johnston Atoll, Palmyra Atoll, Kingman Reef, Wake Island, Jarvis Island, Howland and Baker Islands, and Midway...

33 CFR 3.70-10 - Sector Honolulu Marine Inspection Zone and Captain of the Port Zone.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., including all the islands and atolls of the Hawaiian chain and the adjacent waters of the exclusive economic zone (EEZ); and the following islands and their adjacent waters of the EEZ: American Samoa, Johnston Atoll, Palmyra Atoll, Kingman Reef, Wake Island, Jarvis Island, Howland and Baker Islands, and Midway...

17 CFR 32.13 - Exemption from prohibition of commodity option transactions for trade options on certain...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Exemption from prohibition of commodity option transactions for trade options on certain agricultural commodities. 32.13 Section 32.13 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.13 Exemption from...

Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus

PubMed Central

Fraser, Louise D.; Zhao, Yuan; Lutalo, Pamela M. K.; D'Cruz, David P.; Cason, John; Silva, Joselli S.; Dunn‐Walters, Deborah K.; Nayar, Saba; Cope, Andrew P.

2015-01-01

The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune disease systemic lupus erythematosus (SLE), but not in the systemic autoimmune disease control granulomatosis with polyangiitis. Detection of dual Igκ and Igλ expression by flow cytometry could not be abolished by acid washing or by DNAse treatment to remove any bound polyclonal antibody or complexes, and was retained after two days in culture. Both surface and intracytoplasmic dual light chain expression was evident by flow cytometry and confocal microscopy. We observed reduced frequency of rearrangements of the kappa‐deleting element (KDE) in SLE and an inverse correlation between the frequency of KDE rearrangement and the frequency of dual light chain expressing B cells. We propose that dual expression of Igκ and Igλ by a single B cell may occur in some patients with SLE when this may be a consequence of reduced activity of the KDE. PMID:26036683

17 CFR 5.4 - Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Applicability of part 4 of this chapter to commodity pool operators and commodity trading advisors. 5.4 Section 5.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFF-EXCHANGE FOREIGN CURRENCY TRANSACTIONS § 5.4...

Exclusive Breastfeeding and Clinical Malaria Risk in 6-Month-Old Infants: A Cross-Sectional Study from Kinshasa, Democratic Republic of the Congo.

PubMed

Brazeau, Nicholas F; Tabala, Martine; Kiketa, Landry; Kayembe, Dyna; Chalachala, Jean Lambert; Kawende, Bienvenu; Lapika, Bruno; Meshnick, Steven R; Yotebieng, Marcel

2016-10-05

The World Health Organization recommends exclusive breastfeeding (EBF) for the first 6 months of life. However, the effect of EBF on malaria risk remains unclear. In the present study, 137 EBF infants and 358 non-EBF infants from the Democratic Republic of the Congo were assessed for fever and malaria infections by polymerase chain reaction, at 6 months of age. EBF was associated with a reduced risk of clinical malaria (odds ratio = 0.13; 95% confidence interval = 0.00-0.80), suggesting a protective effect of EBF against malaria. © The American Society of Tropical Medicine and Hygiene.

Does size really matter? A sensitivity analysis of number of seeds in a respondent-driven sampling study of gay, bisexual and other men who have sex with men in Vancouver, Canada.

PubMed

Lachowsky, Nathan John; Sorge, Justin Tyler; Raymond, Henry Fisher; Cui, Zishan; Sereda, Paul; Rich, Ashleigh; Roth, Eric A; Hogg, Robert S; Moore, David M

2016-11-16

Respondent-driven sampling (RDS) is an increasingly used peer chain-recruitment method to sample "hard-to-reach" populations for whom there are no reliable sampling frames. Implementation success of RDS varies; one potential negative factor being the number of seeds used. We conducted a sensitivity analysis on estimates produced using data from an RDS study of gay, bisexual and other men who have sex with men (GBMSM) aged ≥16 years living in Vancouver, Canada. Participants completed a questionnaire on demographics, sexual behavior and substance use. For analysis, we used increasing seed exclusion criteria, starting with all participants and subsequently removing unproductive seeds, chains of ≤1 recruitment waves, and chains of ≤2 recruitment waves. We calculated estimates for three different outcomes (HIV serostatus, condomless anal intercourse with HIV discordant/unknown status partner, and injecting drugs) using three different RDS weighting procedures: RDS-I, RDS-II, and RDS-SS. We also assessed seed dependence with bottleneck analyses and convergence plots. Statistical differences between RDS estimators were assessed through simulation analysis. Overall, 719 participants were recruited, which included 119 seeds and a maximum of 16 recruitment waves (mean chain length = 1.7). The sample of >0 recruitment waves removed unproductive seeds (n = 50/119, 42.0%), resulting in 69 chains (mean length = 3.0). The sample of >1 recruitment waves removed 125 seeds or recruits (17.4% of overall sample), resulting in 37 chains (mean length = 4.8). The final sample of >2 recruitment waves removed a further 182 seeds or recruits (25.3% of overall sample), resulting in 25 chains (mean length = 6.1). Convergence plots and bottleneck analyses of condomless anal intercourse with HIV discordant/unknown status partner and injecting drugs outcomes were satisfactory. For these two outcomes, regardless of seed exclusion criteria used, the crude proportions fell within 95% confidence intervals of all RDS-weighted estimates. Significant differences between the three RDS estimators were not observed. Within a sample of GBMSM in Vancouver, Canada, this RDS study suggests that when equilibrium and homophily are met, although potentially costly and time consuming, analysis is not negatively affected by large numbers of unproductive or lowly productive seeds.

Ultra-high vacuum compatible preparation chain for intermetallic compounds

NASA Astrophysics Data System (ADS)

Bauer, A.; Benka, G.; Regnat, A.; Franz, C.; Pfleiderer, C.

2016-11-01

We report the development of a versatile material preparation chain for intermetallic compounds, which focuses on the realization of a high-purity growth environment. The preparation chain comprises an argon glovebox, an inductively heated horizontal cold boat furnace, an arc melting furnace, an inductively heated rod casting furnace, an optically heated floating-zone furnace, a resistively heated annealing furnace, and an inductively heated annealing furnace. The cold boat furnace and the arc melting furnace may be loaded from the glovebox by means of a load-lock permitting to synthesize compounds starting with air-sensitive elements while handling the constituents exclusively in an inert gas atmosphere. All furnaces are all-metal sealed, bakeable, and may be pumped to ultra-high vacuum. We find that the latter represents an important prerequisite for handling compounds with high vapor pressure under high-purity argon atmosphere. We illustrate the operational aspects of the preparation chain in terms of the single-crystal growth of the heavy-fermion compound CeNi2Ge2.

E3 ligase Rad18 promotes monoubiquitination rather than ubiquitin chain formation by E2 enzyme Rad6

PubMed Central

Hibbert, Richard G.; Huang, Anding; Boelens, Rolf; Sixma, Titia K.

2011-01-01

In ubiquitin conjugation, different combinations of E2 and E3 enzymes catalyse either monoubiquitination or ubiquitin chain formation. The E2/E3 complex Rad6/Rad18 exclusively monoubiquitinates the proliferating cell nuclear antigen (PCNA) to signal for “error prone” DNA damage tolerance, whereas a different set of conjugation enzymes is required for ubiquitin chain formation on PCNA. Here we show that human E2 enzyme Rad6b is intrinsically capable of catalyzing ubiquitin chain formation. This activity is prevented during PCNA ubiquitination by the interaction of Rad6 with E3 enzyme Rad18. Using NMR and X-ray crystallography we show that the R6BD of Rad18 inhibits this activity by competing with ubiquitin for a noncovalent “backside” binding site on Rad6. Our findings provide mechanistic insights into how E3 enzymes can regulate the ubiquitin conjugation process. PMID:21422291

17 CFR 33.3 - Unlawful commodity option transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Unlawful commodity option... REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.3 Unlawful commodity option... of, or maintain a position in, any commodity option transaction subject to the provisions of this...

49 CFR 1248.100 - Commodity classification designated.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 9 2011-10-01 2011-10-01 false Commodity classification designated. 1248.100... STATISTICS Commodity Code § 1248.100 Commodity classification designated. Commencing with reports for the..., reports of commodity statistics required to be made to the Board, shall be based on the commodity codes...

Critical elements in Carlin, epithermal, and orogenic gold deposits

USGS Publications Warehouse

Goldfarb, Richard J.; Hofstra, Albert H.; Simmons, Stuart F.

2016-01-01

Carlin, epithermal, and orogenic gold deposits, today mined almost exclusively for their gold content, have similar suites of anomalous trace elements that reflect similar low-salinity ore fluids and thermal conditions of metal transport and deposition. Many of these trace elements are commonly referred to as critical or near-critical elements or metals and have been locally recovered, although typically in small amounts, by historic mining activities. These elements include As, Bi, Hg, In, Sb, Se, Te, Tl, and W. Most of these elements are now solely recovered as by-products from the milling of large-tonnage, base metal-rich ore deposits, such as porphyry and volcanogenic massive sulfide deposits.A combination of dominance of the world market by a single country for a single commodity and a growing demand for many of the critical to near-critical elements could lead to future recovery of such elements from select epithermal, orogenic, or Carlin-type gold deposits. Antimony continues to be recovered from some orogenic gold deposits and tellurium could potentially be a primary commodity from some such deposits. Tellurium and indium in sphalerite-rich ores have been recovered in the past and could be future commodities recovered from epithermal ores. Carlin-type gold deposits in Nevada are enriched in and may be a future source for As, Hg, Sb, and/or Tl. Some of the Devonian carbonaceous host rocks in the Carlin districts are sufficiently enriched in many trace elements, including Hg, Se, and V, such that they also could become resources. Thallium may be locally enriched to economic levels in Carlin-type deposits and it has been produced from Carlin-like deposits elsewhere in the world (e.g., Alsar, southern Macedonia; Lanmuchang, Guizhou province, China). Mercury continues to be recovered from shallow-level epithermal deposits, as well as a by-product of many Carlin-type deposits where refractory ore is roasted to oxidize carbon and pyrite, and mercury is then captured in air pollution control devices.

17 CFR 33.10 - Fraud in connection with commodity option transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Fraud in connection with commodity option transactions. 33.10 Section 33.10 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.10 Fraud in...

17 CFR 32.11 - Suspension of commodity option transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Suspension of commodity option... REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.11 Suspension of commodity option transactions. (a... accept money, securities or property in connection with, the purchase or sale of any commodity option, or...

7 CFR 65.135 - Covered commodity.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., PEANUTS, AND GINSENG General Provisions Definitions § 65.135 Covered commodity. (a) Covered commodity... nuts; (6) Pecans; and (7) Ginseng. (b) Covered commodities are excluded from this part if the commodity...

7 CFR 65.135 - Covered commodity.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., PEANUTS, AND GINSENG General Provisions Definitions § 65.135 Covered commodity. (a) Covered commodity... nuts; (6) Pecans; and (7) Ginseng. (b) Covered commodities are excluded from this part if the commodity...

7 CFR 65.135 - Covered commodity.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., PEANUTS, AND GINSENG General Provisions Definitions § 65.135 Covered commodity. (a) Covered commodity... nuts; (6) Pecans; and (7) Ginseng. (b) Covered commodities are excluded from this part if the commodity...

7 CFR 65.135 - Covered commodity.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., PEANUTS, AND GINSENG General Provisions Definitions § 65.135 Covered commodity. (a) Covered commodity... nuts; (6) Pecans; and (7) Ginseng. (b) Covered commodities are excluded from this part if the commodity...

17 CFR 33.4 - Designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2011 CFR

2011-04-01

... market for the trading of commodity options. 33.4 Section 33.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.4 Designation as a contract market for the trading of commodity options. The Commission may...

17 CFR 33.4 - Designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2012 CFR

2012-04-01

... market for the trading of commodity options. 33.4 Section 33.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.4 Designation as a contract market for the trading of commodity options. The Commission may...

Simulation of size-exclusion chromatography distribution coefficients of comb-shaped molecules in spherical pores comparison of simulation and experiment.

PubMed

Radke, Wolfgang

2004-03-05

Simulations of the distribution coefficients of linear polymers and regular combs with various spacings between the arms have been performed. The distribution coefficients were plotted as a function of the number of segments in order to compare the size exclusion chromatography (SEC)-elution behavior of combs relative to linear molecules. By comparing the simulated SEC-calibration curves it is possible to predict the elution behavior of comb-shaped polymers relative to linear ones. In order to compare the results obtained by computer simulations with experimental data, a variety of comb-shaped polymers varying in side chain length, spacing between the side chains and molecular weights of the backbone were analyzed by SEC with light-scattering detection. It was found that the computer simulations could predict the molecular weights of linear molecules having the same retention volume with an accuracy of about 10%, i.e. the error in the molecular weight obtained by calculating the molecular weight of the comb-polymer based on a calibration curve constructed using linear standards and the results of the computer simulations are of the same magnitude as the experimental error of absolute molecular weight determination.

Determination of short chain carboxylic acids in vegetable oils and fats using ion exclusion chromatography electrospray ionization mass spectrometry.

PubMed

Viidanoja, Jyrki

2015-02-27

A new method for quantification of short chain C1-C6 carboxylic acids in vegetable oils and fats by employing Liquid Chromatography Mass Spectrometry (LC-MS) has been developed. The method requires minor sample preparation and applies non-conventional Electrospray Ionization (ESI) liquid phase chemistry. Samples are first dissolved in chloroform and then extracted using water that has been spiked with stable isotope labeled internal standards that are used for signal normalization and absolute quantification of selected acids. The analytes are separated using Ion Exclusion Chromatography (IEC) and detected with Electrospray Ionization Mass Spectrometry (ESI-MS) as deprotonated molecules. Prior to ionization the eluent that contains hydrochloric acid is modified post-column to ensure good ionization efficiency of the analytes. The averaged within run precision and between run precision were generally lower than 8%. The accuracy was between 85 and 115% for most of the analytes. The Lower Limit of Quantification (LLOQ) ranged from 0.006 to 7mg/kg. It is shown that this method offers good selectivity in cases where UV detection fails to produce reliable results. Copyright © 2015 Elsevier B.V. All rights reserved.

Critical conditions of polymer adsorption and chromatography on non-porous substrates.

PubMed

Cimino, Richard T; Rasmussen, Christopher J; Brun, Yefim; Neimark, Alexander V

2016-07-15

We present a novel thermodynamic theory and Monte Carlo simulation model for adsorption of macromolecules to solid surfaces that is applied for calculating the chain partition during separation on chromatographic columns packed with non-porous particles. We show that similarly to polymer separation on porous substrates, it is possible to attain three chromatographic modes: size exclusion chromatography at very weak or no adsorption, liquid adsorption chromatography when adsorption effects prevail, and liquid chromatography at critical conditions that occurs at the critical point of adsorption. The main attention is paid to the analysis of the critical conditions, at which the retention is chain length independent. The theoretical results are verified with specially designed experiments on isocratic separation of linear polystyrenes on a column packed with non-porous particles at various solvent compositions. Without invoking any adjustable parameters related to the column and particle geometry, we describe quantitatively the observed transition between the size exclusion and adsorption separation regimes upon the variation of solvent composition, with the intermediate mode occurring at a well-defined critical point of adsorption. A relationship is established between the experimental solvent composition and the effective adsorption potential used in model simulations. Copyright © 2016 Elsevier Inc. All rights reserved.

Pre- and postharvest preventive measures and intervention strategies to control microbial food safety hazards of fresh leafy vegetables.

PubMed

Gil, Maria I; Selma, Maria V; Suslow, Trevor; Jacxsens, Liesbeth; Uyttendaele, Mieke; Allende, Ana

2015-01-01

This review includes an overview of the most important preventive measures along the farm to fork chain to prevent microbial contamination of leafy greens. It also includes the technological and managerial interventions related to primary production, postharvest handling, processing practices, distribution, and consumer handling to eliminate pathogens in leafy greens. When the microbiological risk is already present, preventive measures to limit actual contamination events or pathogen survival are considered intervention strategies. In codes of practice the focus is mainly put on explaining preventive measures. However, it is also important to establish more focused intervention strategies. This review is centered mainly on leafy vegetables as the commodity identified as the highest priority in terms of fresh produce microbial safety from a global perspective. There is no unique preventive measure or intervention strategy that could be applied at one point of the food chain. We should encourage growers of leafy greens to establish procedures based on the HACCP principles at the level of primary production. The traceability of leafy vegetables along the chain is an essential element in ensuring food safety. Thus, in dealing with the food safety issues associated with fresh produce it is clear that a multidisciplinary farm to fork strategy is required.

17 CFR 33.5 - Application for designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2011 CFR

2011-04-01

... a contract market for the trading of commodity options. 33.5 Section 33.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.5 Application for designation as a contract market for the trading of commodity options. (a...

17 CFR 37.4 - Election to trade excluded and exempt commodities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Election to trade excluded and exempt commodities. 37.4 Section 37.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DERIVATIVES TRANSACTION EXECUTION FACILITIES § 37.4 Election to trade excluded and exempt commodities. A board of trade that is or elects...

17 CFR 33.5 - Application for designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2013 CFR

2013-04-01

... a contract market for the trading of commodity options. 33.5 Section 33.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS THAT ARE OPTIONS... contract market for the trading of commodity options. (a) Any board of trade desiring to be designated as a...

17 CFR 33.5 - Application for designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2012 CFR

2012-04-01

... a contract market for the trading of commodity options. 33.5 Section 33.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.5 Application for designation as a contract market for the trading of commodity options. (a...

17 CFR 33.6 - Suspension or revocation of designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2013 CFR

2013-04-01

... designation as a contract market for the trading of commodity options. 33.6 Section 33.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS THAT... designation as a contract market for the trading of commodity options. The Commission may, after notice and...

17 CFR 33.4 - Designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2013 CFR

2013-04-01

... market for the trading of commodity options. 33.4 Section 33.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS THAT ARE OPTIONS ON CONTRACTS OF SALE OF A COMMODITY FOR FUTURE DELIVERY § 33.4 Designation as a contract market for the trading...

17 CFR 33.5 - Application for designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a contract market for the trading of commodity options. 33.5 Section 33.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.5 Application for designation as a contract market for the trading of commodity options. (a...

17 CFR 210.4-08 - General notes to financial statements.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., options, and other financial instruments with similar characteristics. (ii) Derivative commodity... futures, commodity forwards, commodity swaps, commodity options, and other commodity instruments with... policies for certain derivative instruments. Disclosures regarding accounting policies shall include...

Integrable dissipative exclusion process: Correlation functions and physical properties

NASA Astrophysics Data System (ADS)

Crampe, N.; Ragoucy, E.; Rittenberg, V.; Vanicat, M.

2016-09-01

We study a one-parameter generalization of the symmetric simple exclusion process on a one-dimensional lattice. In addition to the usual dynamics (where particles can hop with equal rates to the left or to the right with an exclusion constraint), annihilation and creation of pairs can occur. The system is driven out of equilibrium by two reservoirs at the boundaries. In this setting the model is still integrable: it is related to the open XXZ spin chain through a gauge transformation. This allows us to compute the full spectrum of the Markov matrix using Bethe equations. We also show that the stationary state can be expressed in a matrix product form permitting to compute the multipoints correlation functions as well as the mean value of the lattice and the creation-annihilation currents. Finally, the variance of the lattice current is computed for a finite-size system. In the thermodynamic limit, it matches the value obtained from the associated macroscopic fluctuation theory.

Occurrence of C-Terminal Residue Exclusion in Peptide Fragmentation by ESI and MALDI Tandem Mass Spectrometry

NASA Astrophysics Data System (ADS)

Dupré, Mathieu; Cantel, Sonia; Martinez, Jean; Enjalbal, Christine

2012-02-01

By screening a data set of 392 synthetic peptides MS/MS spectra, we found that a known C-terminal rearrangement was unexpectedly frequently occurring from monoprotonated molecular ions in both ESI and MALDI tandem mass spectrometry upon low and high energy collision activated dissociations with QqTOF and TOF/TOF mass analyzer configuration, respectively. Any residue localized at the C-terminal carboxylic acid end, even a basic one, was lost, provided that a basic amino acid such arginine and to a lesser extent histidine and lysine was present in the sequence leading to a fragment ion, usually depicted as (bn-1 + H2O) ion, corresponding to a shortened non-scrambled peptide chain. Far from being an epiphenomenon, such a residue exclusion from the peptide chain C-terminal extremity gave a fragment ion that was the base peak of the MS/MS spectrum in certain cases. Within the frame of the mobile proton model, the ionizing proton being sequestered onto the basic amino acid side chain, it is known that the charge directed fragmentation mechanism involved the C-terminal carboxylic acid function forming an anhydride intermediate structure. The same mechanism was also demonstrated from cationized peptides. To confirm such assessment, we have prepared some of the peptides that displayed such C-terminal residue exclusion as a C-terminal backbone amide. As expected in this peptide amide series, the production of truncated chains was completely suppressed. Besides, multiply charged molecular ions of all peptides recorded in ESI mass spectrometry did not undergo such fragmentation validating that any mobile ionizing proton will prevent such a competitive C-terminal backbone rearrangement. Among all well-known nondirect sequence fragment ions issued from non specific loss of neutral molecules (mainly H2O and NH3) and multiple backbone amide ruptures (b-type internal ions), the described C-terminal residue exclusion is highly identifiable giving raise to a single fragment ion in the high mass range of the MS/MS spectra. The mass difference between this signal and the protonated molecular ion corresponds to the mass of the C-terminal residue. It allowed a straightforward identification of the amino acid positioned at this extremity. It must be emphasized that a neutral residue loss can be misattributed to the formation of a ym-1 ion, i.e., to the loss of the N-terminal residue following the a1-ym-1 fragmentation channel. Extreme caution must be adopted when reading the direct sequence ion on the positive ion MS/MS spectra of singly charged peptides not to mix up the attribution of the N- and C-terminal amino acids. Although such peculiar fragmentation behavior is of obvious interest for de novo peptide sequencing, it can also be exploited in proteomics, especially for studies involving digestion protocols carried out with proteolytic enzymes other than trypsin (Lys-N, Glu-C, and Asp-N) that produce arginine-containing peptides.

Engendering the metabolic rift: A feminist political ecology of agrofuels

NASA Astrophysics Data System (ADS)

Dockstader, Sue

This thesis analyzes the gendered impacts of plant-based alternatives to petroleum, commonly called biofuels. Synthesizing case studies, scientific research and policies papers, this theoretical work adopts the term "agrofuels" coined by the peasant organization La Via Campesina to reflect the true nature of these commodities---one of dispossession and ecological destruction. This paper documents the falsity of the claim that the fuels are "sustainable" by presenting facts linking them to deforestation, loss and pollution of water sources, destruction of important biodiversity and the knowledge that maintains this diversity, as well as economic exploitation. Most importantly, I verify that the adoption of agrofuel expansion exacerbates gendered patterns of exclusion and, in most cases, worsens women's positions within the communities targeted for feedstock production with regard to land tenure, household energy maintenance, independent income and physical integrity.

The PI3K p110delta is required for down-regulation of RAG expression in immature B cells.

PubMed

Llorian, Miriam; Stamataki, Zania; Hill, Susan; Turner, Martin; Mårtensson, Inga-Lill

2007-02-15

At the immature B cell stage the BCR signals the down-regulation of the RAG genes and Ig L chain (LC) allelic and isotype exclusion. The signaling pathway that regulates these events is poorly characterized. We demonstrate that immature B cells from mice deficient in the PI3K catalytic subunit p110delta fail to suppress RAG expression and inappropriately recombine kappa and lambda LC loci. In addition, in the presence of the autoantigen, clonal deletion and receptor editing still takes place, demonstrating that these processes are independent of p110delta. These results demonstrate a role for p110delta in the regulation of RAG gene expression and thereby LC allelic/isotype exclusion.

[Research progress on standards of commodity classes of Chinese materia medica and discussion on several key problems].

PubMed

Yang, Guang; Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Jin, Yan; Zheng, Yu-Guang; Wang, Yong-Yan

2014-05-01

Standards of commodity classes of Chinese materia medica is an important way to solve the "Lemons Problem" of traditional Chinese medicine market. Standards of commodity classes are also helpful to rebuild market mechanisms for "high price for good quality". The previous edition of commodity classes standards of Chinese materia medica was made 30 years ago. It is no longer adapted to the market demand. This article researched progress on standards of commodity classes of Chinese materia medica. It considered that biological activity is a better choice than chemical constituents for standards of commodity classes of Chinese materia medica. It is also considered that the key point to set standards of commodity classes is finding the influencing factors between "good quality" and "bad quality". The article also discussed the range of commodity classes of Chinese materia medica, and how to coordinate standards of pharmacopoeia and commodity classes. According to different demands, diversiform standards can be used in commodity classes of Chinese materia medica, but efficacy is considered the most important index of commodity standard. Decoction pieces can be included in standards of commodity classes of Chinese materia medica. The authors also formulated the standards of commodity classes of Notoginseng Radix as an example, and hope this study can make a positive and promotion effect on traditional Chinese medicine market related research.

New Directions in Online Fraud

NASA Astrophysics Data System (ADS)

Mohatar, Oscar Delgado; Sierra Cámara, José M.

2007-12-01

The security of a system can be seen as a chain of protection methods, and the global level is just as strong as its weakest link. From this point of view, cryptography is no more than other link in the chain. And most of the times, it is probably the strongest link, but there are many others weak links which decrease the security level until unacceptable level for carrying out electronic commerce. In last term, exclusively technical protection methods seem not be able to completely resolve the situation. The focus should be changed towards trying to increase the resistance of the system, instead of its invulnerability that, in any case, can not be completely achieved in general purpose operating systems.

Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.

PubMed

Fraser, Louise D; Zhao, Yuan; Lutalo, Pamela M K; D'Cruz, David P; Cason, John; Silva, Joselli S; Dunn-Walters, Deborah K; Nayar, Saba; Cope, Andrew P; Spencer, Jo

2015-08-01

The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune disease systemic lupus erythematosus (SLE), but not in the systemic autoimmune disease control granulomatosis with polyangiitis. Detection of dual Igκ and Igλ expression by flow cytometry could not be abolished by acid washing or by DNAse treatment to remove any bound polyclonal antibody or complexes, and was retained after two days in culture. Both surface and intracytoplasmic dual light chain expression was evident by flow cytometry and confocal microscopy. We observed reduced frequency of rearrangements of the kappa-deleting element (KDE) in SLE and an inverse correlation between the frequency of KDE rearrangement and the frequency of dual light chain expressing B cells. We propose that dual expression of Igκ and Igλ by a single B cell may occur in some patients with SLE when this may be a consequence of reduced activity of the KDE. © 2015 The Authors. European Journal of Immunology published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

17 CFR 32.5 - Disclosure.

Code of Federal Regulations, 2010 CFR

2010-04-01

... effect of any foreign currency fluctuations with respect to commodity option transactions which are to be... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Disclosure. 32.5 Section 32.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION...

17 CFR 31.6 - Registration of leverage commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... commodities. 31.6 Section 31.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... applied to the National Futures Association for registration as a leverage transaction merchant; (2... the spot, forward, and futures markets for the generic commodity; (3) Specify a commercial or retail...

7 CFR 250.57 - Commodity schools.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Commodity schools. 250.57 Section 250.57 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.57 Commodity schools. (a) Categorization of commodity schools. Commodity...

7 CFR 250.57 - Commodity schools.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Commodity schools. 250.57 Section 250.57 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION National School Lunch Program (NSLP) and Other Child Nutrition Programs § 250.57 Commodity schools. (a) Categorization of commodity schools. Commodity...

17 CFR 14.4 - Violation of Commodity Exchange Act.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Violation of Commodity Exchange Act. 14.4 Section 14.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... Exchange Act. The Commission may deny, temporarily or permanently, the privilege of appearing or practicing...

17 CFR 3.10 - Registration of futures commission merchants, retail foreign exchange dealers, introducing...

Code of Federal Regulations, 2011 CFR

2011-04-01

..., commodity pool operators and leverage transaction merchants. 3.10 Section 3.10 Commodity and Securities..., commodity pool operators and leverage transaction merchants. (a) Application for registration. (1)(i) Except... merchant, retail foreign exchange dealers, introducing broker, commodity trading advisor, commodity pool...

Continuous gradient temperature Raman spectroscopy and differential scanning calorimetry of N-3DPA and DHA from -100 to 10°C

USDA-ARS?s Scientific Manuscript database

Docosahexaenoic acid (DHA, 22:6n-3) is exclusively utilized in fast signal processing tissues such as retinal, neural and cardiac. N-3 docosapentaenoic acid (n-3DPA, 22:5n-3), with just one less double bond, is also found in the marine food chain yet cannot substitute for DHA. Gradient Temperature R...

26 CFR 1.883-1 - Exclusion of income from the international operation of ships or aircraft.

Code of Federal Regulations, 2014 CFR

2014-04-01

... charter), space, slot, or block-seat charter, or dry lease, as those terms are defined in paragraph (e)(5... connection with passenger aircraft this sort of charter may be referred to as the sale of block seats. (ix... how the ship or aircraft is used by the lowest-tier lessee in the chain of lessees (as provided in...

26 CFR 1.883-1 - Exclusion of income from the international operation of ships or aircraft.

Code of Federal Regulations, 2013 CFR

2013-04-01

... charter), space, slot, or block-seat charter, or dry lease, as those terms are defined in paragraph (e)(5... connection with passenger aircraft this sort of charter may be referred to as the sale of block seats. (ix... how the ship or aircraft is used by the lowest-tier lessee in the chain of lessees (as provided in...

26 CFR 1.883-1 - Exclusion of income from the international operation of ships or aircraft.

Code of Federal Regulations, 2011 CFR

2011-04-01

... charter), space, slot, or block-seat charter, or dry lease, as those terms are defined in paragraph (e)(5... connection with passenger aircraft this sort of charter may be referred to as the sale of block seats. (ix... how the ship or aircraft is used by the lowest-tier lessee in the chain of lessees (as provided in...

26 CFR 1.883-1 - Exclusion of income from the international operation of ships or aircraft.

Code of Federal Regulations, 2012 CFR

2012-04-01

... charter), space, slot, or block-seat charter, or dry lease, as those terms are defined in paragraph (e)(5... connection with passenger aircraft this sort of charter may be referred to as the sale of block seats. (ix... how the ship or aircraft is used by the lowest-tier lessee in the chain of lessees (as provided in...

Interaction between glycosaminoglycans and immunoglobulin light chains.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, X.; Myatt, E.; Lykos, P.

1997-01-01

Amyloidosis is a pathological process in which normally soluble proteins polymerize to form insoluble fibrils (amyloid). Amyloid formation is found in a number of diseases, including Alzheimer's disease, adult-onset diabetes, and light-chain-associated amyloidosis. No pharmaceutical methods currently exist to prevent this process or to remove the fibrils from tissue. The search for treatment and prevention methods is hampered by a limited understanding of the biophysical basis of amyloid formation. Glycosaminoglycans (GAGs) are long, unbranched heteropolysaccharides composed of repeating disaccharide subunits and are known to associate with amyloid fibrils. The interaction of amyloid-associated free light chains with GAGs was tested bymore » both size-exclusion high-performance liquid chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis experiments. The results indicated that heparin 16 000 and chondroitin sulfate B and C precipitated both human intact light chains and recombinant light chain variable domains. Although all light chains interacted with heparin, the strongest interactions were obtained with proteins that had formed amyloid. Molecular modeling indicated the possibility of interaction between heparin and the conserved saddle like surface of the light chain dimer opposite the complementarity-determining segments that form part of the antigen-binding site of a functional antibody. This suggestion might offer a new path to block the aggregation of amyloid-associated light chain proteins, by design of antagonists based on properties of GAG binding. A hexasaccharide was modeled as the basis for a possible antagonist.« less

Interprofessional communication failures in acute care chains: How can we identify the causes?

PubMed

van Leijen-Zeelenberg, Janneke E; van Raak, Arno J A; Duimel-Peeters, Inge G P; Kroese, Mariëlle E A L; Brink, Peter R G; Vrijhoef, Hubertus J M

2015-01-01

Although communication failures between professionals in acute care delivery occur, explanations for these failures remain unclear. We aim to gain a deeper understanding of interprofessional communication failures by assessing two different explanations for them. A multiple case study containing six cases (i.e. acute care chains) was carried out in which semi-structured interviews, physical artifacts and archival records were used for data collection. Data were entered into matrices and the pattern-matching technique was used to examine the two complementary propositions. Based on the level of standardization and integration present in the acute care chains, the six acute care chains could be divided into two categories of care processes, with the care chains equally distributed among the categories. Failures in communication occurred in both groups. Communication routines were embedded within organizations and descriptions of communication routines in the entire acute care chain could not be found. Based on the results, failures in communication could not exclusively be explained by literature on process typology. Literature on organizational routines was useful to explain the occurrence of communication failures in the acute care chains. Organizational routines can be seen as repetitive action patterns and play an important role in organizations, as most processes are carried out by means of routines. The results of this study imply that it is useful to further explore the role of organizational routines on interprofessional communication in acute care chains to develop a solution for failures in handover practices.

Reactive Nanoparticles Compatibilized Immiscible Polymer Blends: Synthesis of Reactive SiO2 with Long Poly(methyl methacrylate) Chains and the in Situ Formation of Janus SiO2 Nanoparticles Anchored Exclusively at the Interface.

PubMed

Wang, Hengti; Fu, Zhiang; Zhao, Xuewen; Li, Yongjin; Li, Jingye

2017-04-26

The exclusive location of compatibilizers at the interface of immiscible binary polymer blends to bridge the neighboring phases is the most important issue for fabricating desirable materials with synergistic properties. However, the positional stability of the compatibilizers at the interface remains a challenge in both scientific and technical points of view due to the intrinsic flexibility of compatibilizer molecules against aggressive processing conditions. Herein, taking the typical immiscible poly vinylidene fluoride (PVDF)/polylactic acid (PLLA) blend as an example, we demonstrate a novel approach, termed as the interfacial nanoparticle compatibilization (IPC) mechanism, to overcome the challenges by packing nanoparticles thermodynamically at the interface through melt reactive blending. Specifically, we have first synthesized nanosilica with both reactive epoxide groups and long poly(methyl methacrylate) (PMMA) tails, called reactive PMMA-graft-SiO 2 (Epoxy-MSiO 2 ), and then incorporated the Epoxy-MSiO 2 into the PVDF/PLLA (50/50, w/w) blends by melt blending. PLLA was in situ grafted onto SiO 2 by the reaction of the carboxylic acid groups with epoxide groups on the surface of SiO 2 . Therefore, the reacted SiO 2 particles were exclusively located at the interface by the formation of the Janus-faced silica hybrid nanoparticles (JSNp) with pregrafted PMMA tails entangled with PVDF molecular chains in the PVDF phase and the in situ grafted PLLA chains embedded in the PLLA phase. Such JSNp with a distinct hemisphere, functioning as compatibilizer, can not only suppress coalescence of PVDF domains by its steric repulsion but also enhance interfacial adhesion via the selective interactions with the corresponding miscible phase. The interfacial location of JSNp is very stable even under the severe shear field and annealing in the melt. This IPC mechanism paves a new possibility to use the various types of nanoparticles as both effective compatibilizers and functional fillers for immiscible polymer blends.

29 CFR 780.114 - Wild commodities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Agricultural Or Horticultural Commodities § 780.114 Wild commodities. Employees engaged in the gathering or harvesting of wild commodities such as mosses, wild rice, burls and laurel plants, the trapping of wild... 29 Labor 3 2013-07-01 2013-07-01 false Wild commodities. 780.114 Section 780.114 Labor Regulations...

29 CFR 780.114 - Wild commodities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Agricultural Or Horticultural Commodities § 780.114 Wild commodities. Employees engaged in the gathering or harvesting of wild commodities such as mosses, wild rice, burls and laurel plants, the trapping of wild... 29 Labor 3 2011-07-01 2011-07-01 false Wild commodities. 780.114 Section 780.114 Labor Regulations...

29 CFR 780.114 - Wild commodities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Agricultural Or Horticultural Commodities § 780.114 Wild commodities. Employees engaged in the gathering or harvesting of wild commodities such as mosses, wild rice, burls and laurel plants, the trapping of wild... 29 Labor 3 2014-07-01 2014-07-01 false Wild commodities. 780.114 Section 780.114 Labor Regulations...

29 CFR 780.114 - Wild commodities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Agricultural Or Horticultural Commodities § 780.114 Wild commodities. Employees engaged in the gathering or harvesting of wild commodities such as mosses, wild rice, burls and laurel plants, the trapping of wild... 29 Labor 3 2010-07-01 2010-07-01 false Wild commodities. 780.114 Section 780.114 Labor Regulations...

29 CFR 780.114 - Wild commodities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Agricultural Or Horticultural Commodities § 780.114 Wild commodities. Employees engaged in the gathering or harvesting of wild commodities such as mosses, wild rice, burls and laurel plants, the trapping of wild... 29 Labor 3 2012-07-01 2012-07-01 false Wild commodities. 780.114 Section 780.114 Labor Regulations...

17 CFR 37.3 - Requirements for underlying commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 5a(b)(3) of the Act, may trade any contract of sale of a commodity for future delivery (or option on... that are a security futures product, and the registered derivatives transaction execution facility is a... commodities. 37.3 Section 37.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION...

17 CFR 4.32 - Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Trading on a Registered... Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Commodity Trading Advisors § 4.32 Trading on a Registered Derivatives Transaction Execution...

17 CFR 32.3 - Unlawful commodity option transactions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Unlawful commodity option... REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.3 Unlawful commodity option transactions. (a) On and after... extend credit in lieu thereof) from an option customer as payment of the purchase price in connection...

17 CFR 37.4 - Election to trade excluded and exempt commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Election to trade excluded and exempt commodities. 37.4 Section 37.4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DERIVATIVES TRANSACTION EXECUTION FACILITIES § 37.4 Election to trade excluded and exempt...

17 CFR 4.32 - Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Trading on a Registered... Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Commodity Trading Advisors § 4.32 Trading on a Registered Derivatives Transaction Execution...

49 CFR 1248.100 - Commodity classification designated.

Code of Federal Regulations, 2010 CFR

2010-10-01

... STATISTICS Commodity Code § 1248.100 Commodity classification designated. Commencing with reports for the..., reports of commodity statistics required to be made to the Board, shall be based on the commodity codes... Statistics, 1963, issued by the Bureau of the Budget, and on additional codes 411 through 462 shown in § 1248...

Multiple commodities in statistical microeconomics: Model and market

NASA Astrophysics Data System (ADS)

Baaquie, Belal E.; Yu, Miao; Du, Xin

2016-11-01

A statistical generalization of microeconomics has been made in Baaquie (2013). In Baaquie et al. (2015), the market behavior of single commodities was analyzed and it was shown that market data provides strong support for the statistical microeconomic description of commodity prices. The case of multiple commodities is studied and a parsimonious generalization of the single commodity model is made for the multiple commodities case. Market data shows that the generalization can accurately model the simultaneous correlation functions of up to four commodities. To accurately model five or more commodities, further terms have to be included in the model. This study shows that the statistical microeconomics approach is a comprehensive and complete formulation of microeconomics, and which is independent to the mainstream formulation of microeconomics.

The Influence Of Highway Transportation Infrastructure Condition Toward Commodity Production Generation for The Resilience Needs at Regional Internal Zone

NASA Astrophysics Data System (ADS)

Akbardin, Juang; Parikesit, Danang; Riyanto, Bambang; Mulyono, Agus Taufik

2018-02-01

The poultry commodity consumption and requirement is one of the main commodities that must be fulfilled in a region to maintain the availability of meat from poultry. Poultry commodity production is one of the production sectors that have a clean environment resistance. An increasing of poultry commodity generation production requires a smooth distribution to arrive at the processing. The livestock location as a commodity production is placed at a considerable far distance from residential and market locations. Zones that have poultry commodity production have an excess potential to supply other zones that are lacking in production to the consumption of these commodities. The condition of highway transportation infrastructure that is very diverse with the damage level availability in a zone has an influence in the supply and demand of poultry commodity requirement in the regional internal of Central Java province. In order to know the effect of highway transportation infrastructure condition toward the poultry commodity movement, demography factor and availability of freight vehicles will be reviewed to estimate the amount of poultry commodity movement generation production. Thus the poultry commodity consumption requirement that located in the internal - regional zone of central java province can be adequated from the zone. So it can be minimized the negative impacts that affect the environment at the zone in terms of comparison of the movement attraction and generation production at poultry commodity in Central Java.

High-pressure synthesis and characterization of the first cerium fluoride borate CeB{sub 2}O{sub 4}F

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinteregger, Ernst; Wurst, Klaus; Tribus, Martina

2013-08-15

CeB{sub 2}O{sub 4}F is the first cerium fluoride borate, which is exclusively built up of one-dimensional, infinite chains of condensed trigonal-planar [BO{sub 3}]{sup 3−} groups. This new cerium fluoride borate was synthesized under high-pressure/high-temperature conditions of 0.9 GPa and 1450 °C in a Walker-type multianvil apparatus. The compound crystallizes in the orthorhombic space group Pbca (No. 61) with eight formula units and the lattice parameters a=821.63(5), b=1257.50(9), c=726.71(6) pm, V=750.84(9) Å{sup 3}, R{sub 1}=0.0698, and wR{sub 2}=0.0682 (all data). The structure exhibits a 9+1 coordinated cerium ion, one three-fold coordinated fluoride ion and a one-dimensional chain of [BO{sub 3}]{sup 3−}more » groups. Furthermore, IR spectroscopy, Electron Micro Probe Analysis and temperature-dependent X-ray powder diffraction measurements were performed. - Graphical abstract: A new rare-earth fluoride borate CeB{sub 2}O{sub 4}F could be synthesized under high-pressure/high-temperature conditions of 0.9 °GPa and 1450 °Cin a Walker-type multianvil apparatus. The crystal structure represents a new structure type in the class of rare-earth fluoride borates. The structure exhibits a 9+1 coordinated cerium ion, one three-fold coordinated fluoride ion and a one-dimensional chain of [BO{sub 3}]{sup 3−} groups. A closer view on the ac-plane shows an interesting wave-like modulation of the borate chains. Highlights: • CeB{sub 2}O{sub 4}F is the first fluoride borate exclusively built up of one-dimensional, infinite chains of condensed trigonal-planar [BO{sub 3}]{sup 3−} groups. • CeB{sub 2}O{sub 4}F is the first cerium fluoride borate. • High-pressure conditions were necessary to synthesize CeB{sub 2}O{sub 4}F.« less

Transforming vaccines supply chains in Nigeria.

PubMed

Sarley, David; Mahmud, Mustafa; Idris, Jide; Osunkiyesi, Modele; Dibosa-Osadolor, Onome; Okebukola, Peter; Wiwa, Owens

2017-04-19

Nigeria is the most populous country in Africa and in 2012 was suffering some of the lowest vaccination rates in the World. A combination of factors had resulted in a dysfunctional immunization cold chain and supply chain. Recognizing that the number of unimmunized children contributed to high levels of under-5-mortality, and that health MDGs would not be attained, Minister of State for Health Mohammed Pate launched a vaccines transformation project in 2013. In partnership with BMGF, GAVI, UNICEF, WHO, other donors and implementing partners the transformation journey has so far taken three years and achieved impressive results. It has though faced challenges along the way and with the financial burden of GAVI graduation facing Nigeria, the economic downturn and the decentralized funding of health services, the results are far from sustained. This paper documents the work undertaken at the Federal level and then highlights specific work undertaken in partnership with Lagos State Government. It identifies the importance of taking an end to end approach and looking at the root causes of weak system performance. The strategy combined simple innovations in how data was captured, recorded and used to drive decision making. It included a comprehensive and systematic approach to cold chain procurement, installation and maintenance with a shift to a culture of active cold chain maintenance that is performing with higher levels of uptime. It also included supply chain redesign at both the Federal and State level. Finally, it involved an institutional transformation at the National Primary Health Care Development Agency (NPHCDA) to establish a data driven Department of Logistics and Health Commodities (DLHC) to manage the many challenges in immunizing 7.5 million children annually. While results have been impressive, there have been many challenges and lessons learned on the way. As Nigeria gets ready for its graduation from GAVI, a robust agile performing cold chain and supply chain will be essential for the good health of Nigeria's children and its economy. The necessary transformation journey has only just begun. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

USDA Foreign Agricultural Service overview for operational monitoring of current crop conditions and production forecasts.

NASA Astrophysics Data System (ADS)

Crutchfield, J.

2016-12-01

The presentation will discuss the current status of the International Production Assessment Division of the USDA ForeignAgricultural Service for operational monitoring and forecasting of current crop conditions, and anticipated productionchanges to produce monthly, multi-source consensus reports on global crop conditions including the use of Earthobservations (EO) from satellite and in situ sources.United States Department of Agriculture (USDA) Foreign Agricultural Service (FAS) International Production AssessmentDivision (IPAD) deals exclusively with global crop production forecasting and agricultural analysis in support of the USDAWorld Agricultural Outlook Board (WAOB) lockup process and contributions to the World Agricultural Supply DemandEstimates (WASE) report. Analysts are responsible for discrete regions or countries and conduct in-depth long-termresearch into national agricultural statistics, farming systems, climatic, environmental, and economic factors affectingcrop production. IPAD analysts become highly valued cross-commodity specialists over time, and are routinely soughtout for specialized analyses to support governmental studies. IPAD is responsible for grain, oilseed, and cotton analysison a global basis. IPAD is unique in the tools it uses to analyze crop conditions around the world, including customweather analysis software and databases, satellite imagery and value-added image interpretation products. It alsoincorporates all traditional agricultural intelligence resources into its forecasting program, to make the fullest use ofavailable information in its operational commodity forecasts and analysis. International travel and training play animportant role in learning about foreign agricultural production systems and in developing analyst knowledge andcapabilities.

Commodes: inconvenient conveniences.

PubMed

Naylor, J R; Mulley, G P

1993-11-13

To investigate use of commodes and attitudes of users and carers to them. Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. 140 users of a commode and 105 of their carers. Main reasons for being supplied with a commode were impaired mobility (130 subjects), difficulty in climbing stairs (128), and urinary incontinence (127). Main concerns of users and carers were lack of privacy (120 subjects felt embarrassed about using their commode, and 96 would not use it if someone was present); unpleasant smells (especially for 20 subjects who were confined to one room); physical appearance of commode chair (101 users said it had an unfavourable appearance, and 44 had tried to disguise it); and lack of follow up after commode was supplied (only 15 users and carers knew who to contact if there were problems). Users generally either had very positive or very negative attitudes to their commodes but most carers viewed them very negatively, especially with regard to cleaning them. Health professionals should be aware of people's need for privacy when advising them where to keep their commode. A standard commode is inappropriate for people confined to one room, and alternatives such as a chemical toilet should be considered. Regular follow up is needed to identify any problems such as uncomfortable or unsafe chairs. More thought should be given to the appearance of commodes in their design.

75 FR 67794 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Order Granting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-03

... commodities or commodity futures, options on commodities, or other commodity derivatives or Commodity-Based... options or other derivatives on any of the foregoing; or (b) interest rate futures or options or... derivatives on any of the foregoing; or (b) interest rate futures or options or derivatives on the foregoing...

17 CFR 15.00 - Definitions of terms used in parts 15 to 21 of this chapter.

Code of Federal Regulations, 2010 CFR

2010-04-01

... commodity, means the actual commodity as distinguished from a futures or options contract in such commodity... for future delivery or commodity option transactions, or for effecting settlements of contracts for future delivery or commodity option transactions, for and between members of any designated contract...

75 FR 71762 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-24

... commodities or commodity futures, options on commodities, or other commodity derivatives or Commodity-Based...) interest rate futures or options or derivatives on the foregoing in this subparagraph (b) (``Futures... options or other derivatives on any of the foregoing; or (b) interest rate futures or options or...

17 CFR 4.14 - Exemption from registration as a commodity trading advisor.

Code of Federal Regulations, 2011 CFR

2011-04-01

... TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS General Provisions, Definitions... commodity pool operator and the person's commodity trading advice is directed solely to, and for the sole use of, the pool or pools for which it is so registered; (5) It is exempt from registration as a...

17 CFR Appendix B to Part 43 - Enumerated Physical Commodity Contracts and Other Contracts

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Enumerated Physical Commodity... TRADING COMMISSION REAL-TIME PUBLIC REPORTING Pt. 43, App. B Appendix B to Part 43—Enumerated Physical Commodity Contracts and Other Contracts Enumerated Physical Commodity Contracts Agriculture ICE Futures U.S...

17 CFR 32.13 - Exemption from prohibition of commodity option transactions for trade options on certain...

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Exemption from prohibition of... Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION... are met at the time of the solicitation or acceptance: (1) That person is registered with the...

17 CFR 4.32 - Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers. 4.32 Section 4.32 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING...

A discrete scattering series representation for lattice embedded models of chain cyclization

NASA Astrophysics Data System (ADS)

Fraser, Simon J.; Winnik, Mitchell A.

1980-01-01

In this paper we develop a lattice based model of chain cyclization in the presence of a set of occupied sites V in the lattice. We show that within the approximation of a Markovian chain propagator the effect of V on the partition function for the system can be written as a time-ordered exponential series in which V behaves like a scattering potential and chainlength is the timelike parameter. The discrete and finite nature of this model allows us to obtain rigorous upper and lower bounds to the series limit. We adapt these formulas to calculation of the partition functions and cyclization probabilities of terminally and globally cyclizing chains. Two classes of cyclization are considered: in the first model the target set H may be visited repeatedly (the Markovian model); in the second case vertices in H may be visited at most once(the non-Markovian or taboo model). This formulation depends on two fundamental combinatorial structures, namely the inclusion-exclusion principle and the set of subsets of a set. We have tried to interpret these abstract structures with physical analogies throughout the paper.

An optimized chemical synthesis of human relaxin-2.

PubMed

Barlos, Kostas K; Gatos, Dimitrios; Vasileiou, Zoe; Barlos, Kleomenis

2010-04-01

Human gene 2 relaxin (RLX) is a member of the insulin superfamily and is a multi-functional factor playing a vital role in pregnancy, aging, fibrosis, cardioprotection, vasodilation, inflammation, and angiogenesis. RLX is currently applied in clinical trials to cure among others acute heart failure, fibrosis, and preeclampsia. The synthesis of RLX by chemical methods is difficult because of the insolubility of its B-chain and the required laborious and low yielding site-directed combination of its A (RLXA) and B (RLXB) chains. We report here that oxidation of the Met(25) residue of RLXB improves its solubility, allowing its effective solid-phase synthesis and application in random interchain combination reactions with RLXA. Linear Met(O)(25)-RLX B-chain (RLXBO) reacts with a mixture of isomers of bicyclic A-chain (bcRLXA) giving exclusively the native interchain combination. Applying this method Met(O)(25)-RLX (RLXO) was obtained in 62% yield and was easily converted to RLX in 78% yield, by reduction with ammonium iodide. Copyright (c) 2010 European Peptide Society and John Wiley & Sons, Ltd.

Kinetic market models with single commodity having price fluctuations

NASA Astrophysics Data System (ADS)

Chatterjee, A.; Chakrabarti, B. K.

2006-12-01

We study here numerically the behavior of an ideal gas like model of markets having only one non-consumable commodity. We investigate the behavior of the steady-state distributions of money, commodity and total wealth, as the dynamics of trading or exchange of money and commodity proceeds, with local (in time) fluctuations in the price of the commodity. These distributions are studied in markets with agents having uniform and random saving factors. The self-organizing features in money distribution are similar to the cases without any commodity (or with consumable commodities), while the commodity distribution shows an exponential decay. The wealth distribution shows interesting behavior: gamma like distribution for uniform saving propensity and has the same power-law tail, as that of the money distribution, for a market with agents having random saving propensity.

A Crosswalk of Mineral Commodity End Uses and North American Industry Classification System (NAICS) codes

USGS Publications Warehouse

Barry, James J.; Matos, Grecia R.; Menzie, W. David

2015-09-14

The links between the end uses of mineral commodities and the NAICS codes provide an instrument for analyzing the use of mineral commodities in the economy. The crosswalk is also a guide, highlighting those industrial sectors in the economy that rely heavily on mineral commodities. The distribution of mineral commodities across the economy is dynamic and does differ from year to year. This report reflects a snapshot of the state of the economy and mineral commodities in 2010.

17 CFR 1.19 - Prohibited trading in certain “puts” and “calls”.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Prohibited trading in certain âputsâ and âcallsâ. 1.19 Section 1.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Prohibited Trading in Commodity Options § 1...

17 CFR 33.6 - Suspension or revocation of designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2011 CFR

2011-04-01

... designation as a contract market for the trading of commodity options. 33.6 Section 33.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.6 Suspension or revocation of designation as a contract market for the trading...

17 CFR 1.19 - Prohibited trading in certain “puts” and “calls”.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Prohibited trading in certain âputsâ and âcallsâ. 1.19 Section 1.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Prohibited Trading in Commodity Options § 1...

17 CFR 33.6 - Suspension or revocation of designation as a contract market for the trading of commodity options.

Code of Federal Regulations, 2012 CFR

2012-04-01

... designation as a contract market for the trading of commodity options. 33.6 Section 33.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF DOMESTIC EXCHANGE-TRADED COMMODITY OPTION TRANSACTIONS § 33.6 Suspension or revocation of designation as a contract market for the trading...

17 CFR 1.19 - Prohibited trading in certain “puts” and “calls”.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Prohibited trading in certain âputsâ and âcallsâ. 1.19 Section 1.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Prohibited Trading in Commodity Options § 1...

17 CFR 1.19 - Prohibited trading in certain “puts” and “calls”.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Prohibited trading in certain âputsâ and âcallsâ. 1.19 Section 1.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Prohibited Trading in Commodity Options § 1...

17 CFR 1.19 - Prohibited trading in certain “puts” and “calls”.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Prohibited trading in certain âputsâ and âcallsâ. 1.19 Section 1.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Prohibited Trading in Commodity Options § 1...

7 CFR 1421.5 - Eligible commodities.

Code of Federal Regulations, 2010 CFR

2010-01-01

...)(1) To be an eligible commodity, the commodity must be merchantable for food, feed, or other uses... poisonous to humans or animals. A commodity containing vomitoxin, aflatoxin, or Aspergillus mold may not be...

7 CFR 1421.5 - Eligible commodities.

Code of Federal Regulations, 2011 CFR

2011-01-01

...)(1) To be an eligible commodity, the commodity must be merchantable for food, feed, or other uses... poisonous to humans or animals. A commodity containing vomitoxin, aflatoxin, or Aspergillus mold may not be...

Commonly Consumed Food Commodities

EPA Pesticide Factsheets

Commonly consumed foods are those ingested for their nutrient properties. Food commodities can be either raw agricultural commodities or processed commodities, provided that they are the forms that are sold or distributed for human consumption. Learn more.

76 FR 28641 - Commodity Pool Operators: Relief From Compliance With Certain Disclosure, Reporting and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... are subject to certain operational and advertising requirements under Part 4, to all other provisions... 4 Advertising, Brokers, Commodity futures, Commodity pool operators, Commodity trading advisors...

Commodes: inconvenient conveniences.

PubMed Central

Naylor, J R; Mulley, G P

1993-01-01

OBJECTIVES--To investigate use of commodes and attitudes of users and carers to them. DESIGN--Interview with semi-structured questionnaire of subjects supplied with commodes from Leeds community appliance centre. SUBJECTS--140 users of a commode and 105 of their carers. RESULTS--Main reasons for being supplied with a commode were impaired mobility (130 subjects), difficulty in climbing stairs (128), and urinary incontinence (127). Main concerns of users and carers were lack of privacy (120 subjects felt embarrassed about using their commode, and 96 would not use it if someone was present); unpleasant smells (especially for 20 subjects who were confined to one room); physical appearance of commode chair (101 users said it had an unfavourable appearance, and 44 had tried to disguise it); and lack of follow up after commode was supplied (only 15 users and carers knew who to contact if there were problems). Users generally either had very positive or very negative attitudes to their commodes but most carers viewed them very negatively, especially with regard to cleaning them. CONCLUSIONS--Health professionals should be aware of people's need for privacy when advising them where to keep their commode. A standard commode is inappropriate for people confined to one room, and alternatives such as a chemical toilet should be considered. Regular follow up is needed to identify any problems such as uncomfortable or unsafe chairs. More thought should be given to the appearance of commodes in their design. Images FIG 1 FIG 2 PMID:8281060

75 FR 27338 - NASDAQ OMX Commodities Clearing-Contract Merchant LLC; NASDAQ OMX Commodities Clearing-Delivery...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. ER10-912-000; ER10-913-000; ER10-914-000] NASDAQ OMX Commodities Clearing--Contract Merchant LLC; NASDAQ OMX Commodities Clearing--Delivery LLC; NASDAQ OMX Commodities Clearing--Finance LLC; Notice of Filing May 6, 2010. Take notice that, on May 3, 2010, NASDAQ OMX Commoditie...

17 CFR Appendix C to Part 4 - Form CTA-PR

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Form CTA-PR C Appendix C to Part 4 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING ADVISORS Pt. 4, App. C Appendix C to Part 4—Form CTA-PR ER24FE12.052 ER24FE12...

The lost art of the covenant: trust as a commodity in health care.

PubMed

Bruhn, John G

2005-01-01

Physicians argue that the advent of managed care has turned medicine into a business and that they spend more time learning the art of doing business than practicing medicine, while losing their professional spirit, patient loyalty, autonomy, and income. Medicine was a business before it was a science. Holding on to Hippocratic ideals in a world of on-demand consumers has made the covenantal physician-patient relationship ineffective and devoid of mutual trust. Physicians have argued that trust is time-dependent and a casualty of time-bound managed care guidelines. The author suggests that the principle of trust is not outdated, not exclusively time-dependent, and is still relevant to a modern Hippocrates loyalist. A relationship of trust is built on the style and quality of verbal and nonverbal communication. Trust is not an acquired trait; it is an expectation resulting from an interactive process of human concern and caring.

Linear alkane polymerization on a gold surface.

PubMed

Zhong, Dingyong; Franke, Jörn-Holger; Podiyanachari, Santhosh Kumar; Blömker, Tobias; Zhang, Haiming; Kehr, Gerald; Erker, Gerhard; Fuchs, Harald; Chi, Lifeng

2011-10-14

In contrast to the many methods of selectively coupling olefins, few protocols catenate saturated hydrocarbons in a predictable manner. We report here the highly selective carbon-hydrogen (C-H) activation and subsequent dehydrogenative C-C coupling reaction of long-chain (>C(20)) linear alkanes on an anisotropic gold(110) surface, which undergoes an appropriate reconstruction by adsorption of the molecules and subsequent mild annealing, resulting in nanometer-sized channels (1.22 nanometers in width). Owing to the orientational constraint of the reactant molecules in these one-dimensional channels, the reaction takes place exclusively at specific sites (terminal CH(3) or penultimate CH(2) groups) in the chains at intermediate temperatures (420 to 470 kelvin) and selects for aliphatic over aromatic C-H activation.

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst

PubMed Central

Theriot, Jordan C.; Ryan, Matthew D.; French, Tracy A.; Pearson, Ryan M.; Miyake, Garret M.

2016-01-01

A standardized technique for atom transfer radical polymerization of vinyl monomers using perylene as a visible-light photocatalyst is presented. The procedure is performed under an inert atmosphere using air- and water-exclusion techniques. The outcome of the polymerization is affected by the ratios of monomer, initiator, and catalyst used as well as the reaction concentration, solvent, and nature of the light source. Temporal control over the polymerization can be exercised by turning the visible light source off and on. Low dispersities of the resultant polymers as well as the ability to chain-extend to form block copolymers suggest control over the polymerization, while chain end-group analysis provides evidence supporting an atom-transfer radical polymerization mechanism. PMID:27166728

17 CFR 41.43 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... options with persons other than brokers, dealers, futures commission merchants, floor brokers, or floor... securities, commodity futures, or commodity options with persons other than brokers, dealers, persons....43 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SECURITY FUTURES PRODUCTS...

75 FR 54794 - Commodity Pool Operators: Relief From Compliance With Certain Disclosure, Reporting and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

... are subject to certain operational \\7\\ and advertising requirements \\8\\ under Part 4, to all other... in 17 CFR Part 4 Advertising, Brokers, Commodity futures, Commodity pool operators, Commodity trading...

78 FR 41384 - Agricultural Advisory Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-10

... COMMODITY FUTURES TRADING COMMISSION Agricultural Advisory Committee Meeting AGENCY: Commodity Futures Trading Commission. ACTION: Notice of Meeting. SUMMARY: The Commodity Futures Trading Commission's... Lachenmayr, Commodity Futures Trading Commission, Three Lafayette Centre, 1155 21st Street NW., Washington...

Research on public logistics centers of Zhenzhou city based on GIS

NASA Astrophysics Data System (ADS)

Zeng, Yuhuai; Chen, Shuisen; Tian, Zhihui; Miao, Quansheng

2008-10-01

The regional public logistics center (PLC) is the intermedium that transports goods or commodity from producer to wholesaler, retailer and end consumer through whole supply chains. According to the Central Place Theory, the PLC should be multi-centric and of more kinds of graded degrees. From the road network planning discipline, an unique index---Importance Degree, is presented to measure the capacity of a PLC. The Importance Degree selects three township criteria: total population, gross industry product and budget income as weights to calculate the weighted vectors by principle component analysis method. Finally, through the clustering analysis, we can get the graded degrees of PLCs. It proves that that this research method is very effective for the road network planning of Zhengzhou City.

Evolving Relationship Structures in Multi-sourcing Arrangements: The Case of Mission Critical Outsourcing

NASA Astrophysics Data System (ADS)

Heitlager, Ilja; Helms, Remko; Brinkkemper, Sjaak

Information Technology Outsourcing practice and research mainly considers the outsourcing phenomenon as a generic fulfilment of the IT function by external parties. Inspired by the logic of commodity, core competencies and economies of scale; assets, existing departments and IT functions are transferred to external parties. Although the generic approach might work for desktop outsourcing, where standardisation is the dominant factor, it does not work for the management of mission critical applications. Managing mission critical applications requires a different approach where building relationships is critical. The relationships involve inter and intra organisational parties in a multi-sourcing arrangement, called an IT service chain, consisting of multiple (specialist) parties that have to collaborate closely to deliver high quality services.

A Study on Market Efficiency of Selected Commodity Derivatives Traded on NCDEX During 2011

NASA Astrophysics Data System (ADS)

Sajipriya, N.

2012-10-01

The study aims at testing the weak form of Efficient Market Hypothesis in the context of an emerging commodity market - National Commodity Derivatives Exchange (NCDEX), which is considered as the prime commodity derivatives market in India. The study considered daily spot and futures prices of five selected commodities traded on NCDEX over 12 month period (the futures contracts originating and expiring during the period January 2011 to December 2011) The five commodities chosen are Pepper, Crude palm Oil, steel silver and Chana as they account for almost two-thirds of the value of agricultural commodity derivatives traded on NCDEX. The results of Run test indicate that both spot and futures prices are weak form efficient

17 CFR 242.401 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... of whose business consists of transactions in securities, commodity futures, or commodity options... securities, commodity futures, or commodity options with persons other than brokers, dealers, persons... M, SHO, ATS, AC, AND NMS AND CUSTOMER MARGIN REQUIREMENTS FOR SECURITY FUTURES Customer Margin...

40 CFR 180.108 - Acephate; tolerances for residues.

Code of Federal Regulations, 2012 CFR

2012-07-01

... phosphoramidothioate, in or on the commodity. Commodity 1 Parts per million Bean, dry, seed 3.0 Bean, succulent 3.0... phosphoramidothioate, in or on the commodity. Commodity Parts per million Bean, dry, seed 1 Bean, succulent 1 Brussels...

40 CFR 180.108 - Acephate; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

... phosphoramidothioate, in or on the commodity. Commodity 1 Parts per million Bean, dry, seed 3.0 Bean, succulent 3.0... phosphoramidothioate, in or on the commodity. Commodity Parts per million Bean, dry, seed 1 Bean, succulent 1 Brussels...

40 CFR 180.108 - Acephate; tolerances for residues.

Code of Federal Regulations, 2014 CFR

2014-07-01

... phosphoramidothioate, in or on the commodity. Commodity 1 Parts per million Bean, dry, seed 3.0 Bean, succulent 3.0... phosphoramidothioate, in or on the commodity. Commodity Parts per million Bean, dry, seed 1 Bean, succulent 1 Brussels...

40 CFR 180.108 - Acephate; tolerances for residues.

Code of Federal Regulations, 2013 CFR

2013-07-01

... phosphoramidothioate, in or on the commodity. Commodity 1 Parts per million Bean, dry, seed 3.0 Bean, succulent 3.0... phosphoramidothioate, in or on the commodity. Commodity Parts per million Bean, dry, seed 1 Bean, succulent 1 Brussels...

17 CFR 162.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... control with a covered affiliate. (b) Clear and conspicuous. The term “clear and conspicuous” means... exchange dealer, commodity trading advisor, commodity pool operator, introducing broker, major swap..., commodity trading advisor, commodity pool operator, introducing broker, major swap participant or swap...

17 CFR 162.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... corporate control with a covered affiliate. (b) Clear and conspicuous. The term “clear and conspicuous... exchange dealer, commodity trading advisor, commodity pool operator, introducing broker, major swap..., commodity trading advisor, commodity pool operator, introducing broker, major swap participant or swap...

17 CFR 162.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... control with a covered affiliate. (b) Clear and conspicuous. The term “clear and conspicuous” means... exchange dealer, commodity trading advisor, commodity pool operator, introducing broker, major swap..., commodity trading advisor, commodity pool operator, introducing broker, major swap participant or swap...

Cross-commodity delay discounting of alcohol and money in alcohol users

PubMed Central

Moody, Lara N.; Tegge, Allison N.; Bickel, Warren K.

2017-01-01

Despite real-world implications, the pattern of delay discounting in alcohol users when the commodities now and later differ has not been well characterized. In this study, 60 participants on Amazon's Mechanical Turk completed the Alcohol Use Disorder Identification Test (AUDIT) to assess severity of use and completed four delay discounting tasks between hypothetical, equivalent amounts of alcohol and money available at five delays. The tasks included two cross-commodity (alcohol now-money later and money now-alcohol later) and two same-commodity (money now-money later and alcohol now-alcohol later) conditions. Delay discounting was significantly associated with clinical cutoffs of the AUDIT for both of the cross-commodity conditions but not for either of the same-commodity delay discounting tasks. The cross-commodity discounting conditions were related to severity of use wherein heavy users discounted future alcohol less and future money more. The change in direction of the discounting effect was dependent on the commodity that was distally available suggesting a distinctive pattern of discounting across commodities when comparing light and heavy alcohol users. PMID:29056767

Cross-commodity delay discounting of alcohol and money in alcohol users.

PubMed

Moody, Lara N; Tegge, Allison N; Bickel, Warren K

2017-06-01

Despite real-world implications, the pattern of delay discounting in alcohol users when the commodities now and later differ has not been well characterized. In this study, 60 participants on Amazon's Mechanical Turk completed the Alcohol Use Disorder Identification Test (AUDIT) to assess severity of use and completed four delay discounting tasks between hypothetical, equivalent amounts of alcohol and money available at five delays. The tasks included two cross-commodity (alcohol now-money later and money now-alcohol later) and two same-commodity (money now-money later and alcohol now-alcohol later) conditions. Delay discounting was significantly associated with clinical cutoffs of the AUDIT for both of the cross-commodity conditions but not for either of the same-commodity delay discounting tasks. The cross-commodity discounting conditions were related to severity of use wherein heavy users discounted future alcohol less and future money more. The change in direction of the discounting effect was dependent on the commodity that was distally available suggesting a distinctive pattern of discounting across commodities when comparing light and heavy alcohol users.

Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases

PubMed Central

Turk, Dušan; Janjić, Vojko; Štern, Igor; Podobnik, Marjetka; Lamba, Doriano; Weis Dahl, Søren; Lauritzen, Connie; Pedersen, John; Turk, Vito; Turk, Boris

2001-01-01

Dipeptidyl peptidase I (DPPI) or cathepsin C is the physiological activator of groups of serine proteases from immune and inflammatory cells vital for defense of an organism. The structure presented shows how an additional domain transforms the framework of a papain-like endopeptidase into a robust oligomeric protease-processing enzyme. The tetrahedral arrangement of the active sites exposed to solvent allows approach of proteins in their native state; the massive body of the exclusion domain fastened within the tetrahedral framework excludes approach of a polypeptide chain apart from its termini; and the carboxylic group of Asp1 positions the N-terminal amino group of the substrate. Based on a structural comparison and interactions within the active site cleft, it is suggested that the exclusion domain originates from a metallo-protease inhibitor. The location of missense mutations, characterized in people suffering from Haim–Munk and Papillon–Lefevre syndromes, suggests how they disrupt the fold and function of the enzyme. PMID:11726493

Forecasting jobs in the supply chain for investments in residential energy efficiency retrofits in Florida

NASA Astrophysics Data System (ADS)

Fobair, Richard C., II

This research presents a model for forecasting the numbers of jobs created in the energy efficiency retrofit (EER) supply chain resulting from an investment in upgrading residential buildings in Florida. This investigation examined material supply chains stretching from mining to project installation for three product types: insulation, windows/doors, and heating, ventilating, and air conditioning (HVAC) systems. Outputs from the model are provided for the project, sales, manufacturing, and mining level. The model utilizes reverse-estimation to forecast the numbers of jobs that result from an investment. Reverse-estimation is a process that deconstructs a total investment into its constituent parts. In this research, an investment is deconstructed into profit, overhead, and hard costs for each level of the supply chain and over multiple iterations of inter-industry exchanges. The model processes an investment amount, the type of work and method of contracting into a prediction of the number of jobs created. The deconstruction process utilizes data from the U.S. Economic Census. At each supply chain level, the cost of labor is reconfigured into full-time equivalent (FTE) jobs (i.e. equivalent to 40 hours per week for 52 weeks) utilizing loaded labor rates and a typical employee mix. The model is sensitive to adjustable variables, such as percentage of work performed per type of product, allocation of worker time per skill level, annual hours for FTE calculations, wage rate, and benefits. This research provides several new insights into job creation. First, it provides definitions that can be used for future research on jobs in supply chains related to energy efficiency. Second, it provides a methodology for future investigators to calculate jobs in a supply chain resulting from an investment in energy efficiency upgrades to a building. The methodology used in this research is unique because it examines gross employment at the sub-industry level for specific commodities. Most research on employment examines the net employment change (job creation less job destruction) at levels for regions, industries, and the aggregate economy. Third, it provides a forecast of the numbers of jobs for an investment in energy efficiency over the entire supply chain for the selected industries and the job factors for major levels of the supply chain.

Influence of the molecular architecture on the adsorption onto solid surfaces: comb-like polymers.

PubMed

Guzmán, Eduardo; Ortega, Francisco; Prolongo, Margarita G; Starov, Victor M; Rubio, Ramón G

2011-09-28

The processes of adsorption of grafted copolymers onto negatively charged surfaces were studied using a dissipative quartz crystal microbalance (D-QCM) and ellipsometry. The control parameters in the study of the adsorption are the existence or absence on the molecular architecture of grafted polyethyleneglycol (PEG) chains with different lengths and the chemical nature of the main chain, poly(allylamine) (PAH) or poly(L-lysine) (PLL). It was found out that the adsorption kinetics of the polymers showed a complex behavior. The total adsorbed amount depends on the architecture of the polymer chains (length of the PEG chains), on the polymer concentration and on the chemical nature of the main chain. The comparison of the thicknesses of the adsorbed layers obtained from D-QCM and from ellipsometry allowed calculation of the water content of the layers that is intimately related to the grafting length. The analysis of D-QCM results also provides information about the shear modulus of the layers, whose values have been found to be typical of a rubber-like polymer system. It is shown that the adsorption of polymers with a charged backbone is not driven exclusively by the electrostatic interactions, but the entropic contributions as a result of the trapping of water in the layer structure are of fundamental importance.

17 CFR Appendix C to Part 1 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false [Reserved] C Appendix C to Part 1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Appendix C to Part 1 [Reserved] ...

Optimizing Ocean Space: Co-siting Open Ocean Aquaculture

NASA Astrophysics Data System (ADS)

Cobb, B. L.; Wickliffe, L. C.; Morris, J. A., Jr.

2016-12-01

In January of 2016, NOAA's National Marine Fisheries Service released the Gulf Aquaculture Plan (GAP) to manage the development of environmentally sound and economically sustainable open ocean finfish aquaculture in the Gulf of Mexico (inside the U.S. Exclusive Economic Zone [EEZ]). The GAP provides the first regulatory framework for aquaculture in federal waters with estimated production of 64 million pounds of finfish, and an estimated economic impact of $264 million annually. The Gulf of Mexico is one of the most industrialized ocean basins in the world, with many existing ocean uses including oil and natural gas production, shipping and commerce, commercial fishing operations, and many protected areas to ensure conservation of valuable ecosystem resources and services. NOAA utilized spatial planning procedures and tools identifying suitable sites for establishing aquaculture through exclusion analyses using authoritative federal and state data housed in a centralized geodatabase. Through a highly collaborative, multi-agency effort a mock permitting exercise was conducted to illustrate the regulatory decision-making process for the Gulf. Further decision-making occurred through exploring co-siting opportunities with oil and natural gas platforms. Logistical co-siting was conducted to reduce overall operational costs by looking at distance to major port and commodity tonnage at each port. Importantly, the process of co-siting allows aquaculture to be coupled with other benefits, including the availability of previously established infrastructure and the reduction of environmental impacts.

17 CFR 1.1 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false [Reserved] 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1 [Reserved] [66 FR 42269, Aug. 10, 2001] ...

75 FR 77576 - General Regulations and Derivatives Clearing Organizations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

... Derivatives Clearing Organizations AGENCY: Commodity Futures Trading Commission. ACTION: Notice of proposed... clearing transactions in commodities for future delivery or commodity option transactions, or for effecting settlements of contracts for future delivery or commodity option transactions, for and between members of any...

40 CFR 414.60 - Applicability; description of the commodity organic chemicals subcategory.

Code of Federal Regulations, 2011 CFR

2011-07-01

... commodity organic chemicals subcategory. 414.60 Section 414.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Commodity Organic Chemicals § 414.60 Applicability; description of the commodity organic chemicals...

40 CFR 414.60 - Applicability; description of the commodity organic chemicals subcategory.

Code of Federal Regulations, 2012 CFR

2012-07-01

... commodity organic chemicals subcategory. 414.60 Section 414.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Commodity Organic Chemicals § 414.60 Applicability; description of the commodity organic chemicals...

40 CFR 414.60 - Applicability; description of the commodity organic chemicals subcategory.

Code of Federal Regulations, 2013 CFR

2013-07-01

... commodity organic chemicals subcategory. 414.60 Section 414.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Commodity Organic Chemicals § 414.60 Applicability; description of the commodity organic chemicals...

40 CFR 414.60 - Applicability; description of the commodity organic chemicals subcategory.

Code of Federal Regulations, 2014 CFR

2014-07-01

... commodity organic chemicals subcategory. 414.60 Section 414.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Commodity Organic Chemicals § 414.60 Applicability; description of the commodity organic chemicals...

40 CFR 414.60 - Applicability; description of the commodity organic chemicals subcategory.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commodity organic chemicals subcategory. 414.60 Section 414.60 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ORGANIC CHEMICALS, PLASTICS, AND SYNTHETIC FIBERS Commodity Organic Chemicals § 414.60 Applicability; description of the commodity organic chemicals...

40 CFR 180.473 - Glufosinate ammonium; tolerances for residues.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 2-amino-4-(hydroxymethylphosphinyl)butanoic acid, in or on the commodity. Commodity Parts per... measuring only the sum of glufosinate ammonium, 2-amino-4-(hydroxymethylphosphinyl)butanoic acid... stoichiometric equivalent of 2-amino-4-(hydroxymethylphosphinyl)butanoic acid, in or on the commodity. Commodity...

26 CFR 4.954-0 - Introduction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... corporation beginning after December 31, 1986. Consequently, any gain or loss (including foreign currency gain.... [Reserved] (f) Commodities transactions. (1) In general. (2) Definitions. (i) Commodity. (ii) Commodities transaction. (3) Definition of the term “qualified active sales”. (i) In general. (ii) Sale of commodities...

26 CFR 4.954-0 - Introduction.

Code of Federal Regulations, 2011 CFR

2011-04-01

... corporation beginning after December 31, 1986. Consequently, any gain or loss (including foreign currency gain.... [Reserved] (f) Commodities transactions. (1) In general. (2) Definitions. (i) Commodity. (ii) Commodities transaction. (3) Definition of the term “qualified active sales”. (i) In general. (ii) Sale of commodities...

7 CFR 17.1 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Secretary of Agriculture SALES OF AGRICULTURAL COMMODITIES MADE AVAILABLE UNDER TITLE I OF THE AGRICULTURAL... commodities by the Commodity Credit Corporation (CCC), through private trade channels to the maximum extent..., as amended (hereinafter called “the Act”). (b) Agricultural commodities agreements. (1) Under the Act...

32 CFR 275.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... dealer in securities or commodities. (9) An investment banker or investment company. (10) A currency... matters. (26) Any futures commission merchant, commodity trading advisor, or commodity pool operator registered, or required to register, under the Commodity Exchange Act that is located inside any State or...

7 CFR 17.1 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Secretary of Agriculture SALES OF AGRICULTURAL COMMODITIES MADE AVAILABLE UNDER TITLE I OF THE AGRICULTURAL... commodities by the Commodity Credit Corporation (CCC), through private trade channels to the maximum extent..., as amended (hereinafter called “the Act”). (b) Agricultural commodities agreements. (1) Under the Act...

77 FR 27444 - Joint CFTC-SEC Advisory Committee on Emerging Regulatory Issues

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-10

... SECURITIES AND EXCHANGE COMMISSION COMMODITY FUTURES TRADING COMMISSION [Release Nos. 34-66932... and Exchange Commission (``SEC'') and Commodity Futures Trading Commission (``CFTC'') (each, an.... Commodity Futures Trading Commission Written comments may be mailed to the Commodity Futures Trading...

17 CFR 1.1 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false [Reserved] 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1 [Reserved] [66 FR 42269, Aug. 10, 2001] ...

17 CFR 1.1 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false [Reserved] 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1 [Reserved] [66 FR 42269, Aug. 10, 2001] ...

17 CFR 1.1 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false [Reserved] 1.1 Section 1.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1 [Reserved] [66 FR 42269, Aug. 10, 2001] ...

A world of minerals in your mobile device

USGS Publications Warehouse

Jenness, Jane E.; Ober, Joyce A.; Wilkins, Aleeza M.; Gambogi, Joseph

2016-09-15

Mobile phones and other high-technology communications devices could not exist without mineral commodities. More than one-half of all components in a mobile device—including its electronics, display, battery, speakers, and more—are made from mined and semiprocessed materials (mineral commodities). Some mineral commodities can be recovered as byproducts during the production and processing of other commodities. As an example, bauxite is mined for its aluminum content, but gallium is recovered during the aluminum production process. The images show the ore minerals (sources) of some mineral commodities that are used to make components of a mobile device. On the reverse side, the map and table depict the major source countries producing these mineral commodities along with how these commodities are used in mobile devices. For more information on minerals, visit http://minerals.usgs.gov.

The critical main-chain length for helix formation in water: determined in a peptide series with alternating Aib and Ala residues exclusively and detected with ECD spectroscopy.

PubMed

Longo, Edoardo; Moretto, Alessandro; Formaggio, Fernando; Toniolo, Claudio

2011-10-01

Critical main-chain length for peptide helix formation in the crystal (solid) state and in organic solvents has been already reported. In this short communication, we describe our results aiming at assessing the aforementioned parameter in water solution. To this goal, we synthesized step-by-step by solution procedures a complete series of N-terminally acetylated, C-terminally methoxylated oligopeptides, characterized only by alternating Aib and Ala residues, from the dimer to the nonamer level. All these compounds were investigated by electronic circular dichroism in the far-UV region in water solution as a function of chemical structure, namely presence/absence of an ester moiety or a negative charge at the C-terminus, and temperature. We find that the critical main-chain lengths for 3(10)- and α-helices, although still formed to a limited extent, in aqueous solution are six and eight residues, respectively. © 2011 Wiley-Liss, Inc.

Structural differences among alkali-soluble arabinoxylans from maize (Zea mays), rice (Oryza sativa), and wheat (Triticum aestivum) brans influence human fecal fermentation profiles.

PubMed

Rose, Devin J; Patterson, John A; Hamaker, Bruce R

2010-01-13

Human fecal fermentation profiles of maize, rice, and wheat bran and their dietary fiber fractions released by alkaline-hydrogen peroxide treatment (principally arabinoxylan) were obtained with the aim of identifying and characterizing fractions associated with high production of short chain fatty acids and a linear fermentation profile for possible application as a slowly fermentable dietary fiber. The alkali-soluble fraction from maize bran resulted in the highest short chain fatty acid production among all samples tested, and was linear over the 24 h fermentation period. Size-exclusion chromatography and (1)H NMR suggested that higher molecular weight and uniquely substituted arabinose side chains may contribute to these properties. Monosaccharide disappearance data suggest that maize and rice bran arabinoxylans are fermented by a debranching mechanism, while wheat bran arabinoxylans likely contain large unsubstituted xylose regions that are fermented preferentially, followed by poor fermentation of the remaining, highly branched oligosaccharides.

A multiple length scale description of the mechanism of elastomer stretching

DOE PAGES

Neuefeind, Joerg C.; Skov, Anne L.; Daniels, John E.; ...

2016-10-03

Conventionally, the stretching of rubber is modeled exclusively by rotations of segments of the embedded polymer chains; i.e. changes in entropy. However models have not been tested on all relevant length scales due to a lack of appropriate probes. Here we present a universal X-ray based method for providing data on the structure of rubbers in the 2–50 Å range. First results relate to the elongation of a silicone rubber. We identify several non-entropic contributions to the free energy and describe the associated structural changes. By far the largest contribution comes from structural changes within the individual monomers, but amongmore » the contributions is also an elastic strain, acting between chains, which is 3–4 orders of magnitude smaller than the macroscopic strain, and of the opposite sign, i.e. extension of polymer chains in the direction perpendicular to the stretch. We find this may be due to trapped entanglements relaxing to positions close to the covalent crosslinks.« less

A multiple length scale description of the mechanism of elastomer stretching

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuefeind, Joerg C.; Skov, Anne L.; Daniels, John E.

Conventionally, the stretching of rubber is modeled exclusively by rotations of segments of the embedded polymer chains; i.e. changes in entropy. However models have not been tested on all relevant length scales due to a lack of appropriate probes. Here we present a universal X-ray based method for providing data on the structure of rubbers in the 2–50 Å range. First results relate to the elongation of a silicone rubber. We identify several non-entropic contributions to the free energy and describe the associated structural changes. By far the largest contribution comes from structural changes within the individual monomers, but amongmore » the contributions is also an elastic strain, acting between chains, which is 3–4 orders of magnitude smaller than the macroscopic strain, and of the opposite sign, i.e. extension of polymer chains in the direction perpendicular to the stretch. We find this may be due to trapped entanglements relaxing to positions close to the covalent crosslinks.« less

Active Site Mutations Change the Cleavage Specificity of Neprilysin

PubMed Central

Sexton, Travis; Hitchcook, Lisa J.; Rodgers, David W.; Bradley, Luke H.; Hersh, Louis B.

2012-01-01

Neprilysin (NEP), a member of the M13 subgroup of the zinc-dependent endopeptidase family is a membrane bound peptidase capable of cleaving a variety of physiological peptides. We have generated a series of neprilysin variants containing mutations at either one of two active site residues, Phe563 and Ser546. Among the mutants studied in detail we observed changes in their activity towards leucine5-enkephalin, insulin B chain, and amyloid β1–40. For example, NEPF563I displayed an increase in preference towards cleaving leucine5-enkephalin relative to insulin B chain, while mutant NEPS546E was less discriminating than neprilysin. Mutants NEPF563L and NEPS546E exhibit different cleavage site preferences than neprilysin with insulin B chain and amyloid ß1–40 as substrates. These data indicate that it is possible to alter the cleavage site specificity of neprilysin opening the way for the development of substrate specific or substrate exclusive forms of the enzyme with enhanced therapeutic potential. PMID:22384224

Preliminary Metallogenic Map of North America; a listing of deposits by commodity

USGS Publications Warehouse

Lee, Michael P.; Guild, Philip White; Schruben, Paul G.

1987-01-01

The 4,215 ore deposits shown on the Preliminary Metallogenic Map of North America and contained in the Metallogenic Map file have been sorted by their principal (first-listed) commodities and grouped into metallic and nonmetallic categories. Deposit listings for 56 individual metals and minerals have been assembled using the data base and are arranged alphabetically by country, political subdivision (for the larger countries), and deposit name. Map numbers, major and minor constituents, geographic coordinates, and a geologic code are given for each deposit; additionally, the relative size and deposit class have been derived from the code and are listed separately. The frequencies of individual commodities and commodity groups by type, geographic distribution, and geologic occurrence are summarized in tables, and the relationships of associated commodities to principal commodities in the data base are emphasized in both tables and brief texts. In all, 49 metals and minerals are listed as principal (first or only) commodities and 7 more are shown as 'major' but not principal commodities. (Commodities listed as 'minor' in the data base were not sorted or tabulated separately.) Metals, divided into six subgroups, predominate over nonmetallic minerals by a ratio of about 7 to 1, although in terms of quantities and value the disparity is not so great. Within the metals group, the ranking according to frequency is as follows: base, precious, iron and alloying, other (antimony, beryllium, and others), nuclear-fuel, and light metals. The most frequently occurring commodity in the Metallogenic Map file is gold. Copper is ranked second, both in number of occurrences and as the principal commodity in deposits. Silver is ranked third in frequency of occurrence; lead and zinc are ranked fourth and fifth, respectively. Iron, ranked sixth in frequency of occurrence as a major commodity, is the third most reported principal commodity in the data base, ahead of silver (ranked fourth), lead (ranked fifth), and zinc (ranked sixth).

7 CFR 1427.22 - Commodity certificate exchanges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Commodity certificate exchanges. 1427.22 Section 1427... Deficiency Payments § 1427.22 Commodity certificate exchanges. (a) For any outstanding marketing assistance loan provided for upland cotton, a producer may purchase a commodity certificate and exchange that...

44 CFR 206.151 - Food commodities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Food commodities. 206.151... Food commodities. (a) The Administrator will assure that adequate stocks of food will be ready and... section, the Administrator may direct the Secretary of Agriculture to purchase food commodities in...

44 CFR 206.151 - Food commodities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Food commodities. 206.151... Food commodities. (a) The Administrator will assure that adequate stocks of food will be ready and... section, the Administrator may direct the Secretary of Agriculture to purchase food commodities in...

44 CFR 206.151 - Food commodities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Food commodities. 206.151... Food commodities. (a) The Administrator will assure that adequate stocks of food will be ready and... section, the Administrator may direct the Secretary of Agriculture to purchase food commodities in...

44 CFR 206.151 - Food commodities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Food commodities. 206.151... Food commodities. (a) The Administrator will assure that adequate stocks of food will be ready and... section, the Administrator may direct the Secretary of Agriculture to purchase food commodities in...

Commodity-based Approach for Evaluating the Value of Freight Moving on Texas’ Roadway Network

DOT National Transportation Integrated Search

2017-12-10

The researchers took a commodity-based approach to evaluate the value of a list of selected commodities moved on the Texas freight network. This approach takes advantage of commodity-specific data sources and modeling processes. It provides a unique ...

22 CFR 228.51 - Commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Commodities. 228.51 Section 228.51 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND... agricultural commodities, motor vehicles, or pharmaceuticals (see § 228.13, “Special source rules requiring...

17 CFR 190.10 - General.

Code of Federal Regulations, 2012 CFR

2012-04-01

... STATEMENT IS FURNISHED TO YOU BECAUSE RULE 190.10 (c) OF THE COMMODITY FUTURES TRADING COMMISSION REQUIRES... any combination of the following: futures commission merchant, commodity option dealer, foreign... “from or for the commodity futures account” or “from or for the commodity options account” of such...

17 CFR 32.6 - Segregation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Segregation. 32.6 Section 32.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.6 Segregation. (a) Any person which accepts money, securities, or property from an option...

17 CFR 32.6 - Segregation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Segregation. 32.6 Section 32.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGULATION OF COMMODITY OPTION TRANSACTIONS § 32.6 Segregation. (a) Any person which accepts money, securities, or property from an option...

7 CFR 1421.110 - Commodity certificate exchanges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... COMMODITIES-MARKETING ASSISTANCE LOANS AND LOAN DEFICIENCY PAYMENTS FOR 2008 THROUGH 2012 Marketing Assistance Loans § 1421.110 Commodity certificate exchanges. (a) For any outstanding marketing assistance loan for... commodity certificate for the marketing assistance loan collateral. (b) The exchange rate is the lesser of...

7 CFR 1488.8 - Documents required after delivery.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURAL COMMODITIES Financing of Export Sales of Agricultural Commodities From Private Stocks Under CCC... delivery. (a) CCC will purchase an exporter's account receivable only if the Treasurer, Commodity Credit... or Assistant Treasurer, CCC, after date of delivery of commodities exported or to be exported under...

7 CFR 1488.8 - Documents required after delivery.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURAL COMMODITIES Financing of Export Sales of Agricultural Commodities From Private Stocks Under CCC... delivery. (a) CCC will purchase an exporter's account receivable only if the Treasurer, Commodity Credit... or Assistant Treasurer, CCC, after date of delivery of commodities exported or to be exported under...

Exclusion of black hole disaster scenarios at the LHC

NASA Astrophysics Data System (ADS)

Koch, Benjamin; Bleicher, Marcus; Stöcker, Horst

2009-02-01

The upcoming high energy experiments at the LHC are one of the most outstanding efforts for a better understanding of nature. It is associated with great hopes in the physics community. But there is also some fear in the public, that the conjectured production of mini black holes might lead to a dangerous chain reaction. In this Letter we summarize the most straightforward arguments that are necessary to rule out such doomsday scenarios.

Manual for Courts-Martial, United States, 1984. 1994 Edition.

DTIC Science & Technology

1994-01-01

cards, forensic labora- that office. tory reports, chain of custody documents, morning (15) Statements in documents ajfecting an interest in reports...Para. 142e of the 1969 Manual, "Polygraph tests and drug-in- gate witnesses. This provision generally restates prior law but rec- duced or hypnosis ...statements of the person in- Rule 615. Exclusion of witnesses terviewed made during a drug-induced or hypnosis -induced inter- Rule 615 is taken from the f

22 CFR 228.52 - Suppliers of commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Suppliers of commodities. 228.52 Section 228.52 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND SERVICES FINANCED BY USAID Waivers § 228.52 Suppliers of commodities. Geographic code changes...

7 CFR 17.2 - Definition of terms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Office of the Secretary of Agriculture SALES OF AGRICULTURAL COMMODITIES MADE AVAILABLE UNDER TITLE I OF... in the second legal entity. CCC. The Commodity Credit Corporation, USDA. Commodity. An agricultural commodity produced in the United States, or product thereof produced in the United States, as specified in...

17 CFR 1.32 - Segregated account; daily computation and record.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Segregated account; daily computation and record. 1.32 Section 1.32 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Recordkeeping § 1.32 Segregated account...

31 CFR 560.533 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... commodities, medicine, and medical devices. 560.533 Section 560.533 Money and Finance: Treasury Regulations... Brokering sales of agricultural commodities, medicine, and medical devices. (a) General license for... agricultural commodities, medicine, and medical devices, provided that the sale and exportation or...

31 CFR 560.533 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commodities, medicine, and medical devices. 560.533 Section 560.533 Money and Finance: Treasury Regulations... Brokering sales of agricultural commodities, medicine, and medical devices. (a) General license for... agricultural commodities, medicine, and medical devices, provided that the sale and exportation or...

Capital dissipation minimization for a class of complex irreversible resource exchange processes

NASA Astrophysics Data System (ADS)

Xia, Shaojun; Chen, Lingen

2017-05-01

A model of a class of irreversible resource exchange processes (REPes) between a firm and a producer with commodity flow leakage from the producer to a competitive market is established in this paper. The REPes are assumed to obey the linear commodity transfer law (LCTL). Optimal price paths for capital dissipation minimization (CDM) (it can measure economic process irreversibility) are obtained. The averaged optimal control theory is used. The optimal REP strategy is also compared with other strategies, such as constant-firm-price operation and constant-commodity-flow operation, and effects of the amount of commodity transferred and the commodity flow leakage on the optimal REP strategy are also analyzed. The commodity prices of both the producer and the firm for the CDM of the REPes with commodity flow leakage change with the time exponentially.

Isotopic and elemental analysis of fish tissues for provenance determination

NASA Astrophysics Data System (ADS)

Zannella, Carmela; Adamo, Paola; Opper, Christine; Schwendinger, Susanne; Knezevic, Sara; Van den Oever, Sabrina; Tchaikovsky, Anastassiya; Zitek, Andreas; Prohaska, Thomas

2017-04-01

The reliable tracing of the productions flows of food products through the entire supply chain is an essential requirement for all types of food commodities qualified by origin, composition and quality. This is a minimum requirement to implement safety for the consumer, enhance consumer confidence and countervail fraudulent practices. One important food commodity is fish and fish products. Reliable methods to trace the origin of fish have become of high importance. The investigation focused on the identification of adequate geochemical marker in fish meat and the corresponding linkage to the ambient water. The Sr/Ca ratio along with the 87Sr/86Sr isotope ratio analyzed by (multi collector) inductively coupled plasma mass spectrometry (MC ICP-MS) proved to be the most potential tools in this respect. For the first time, a direct link of fish meat to water could be accomplished.In addition, fish hard parts (otoliths, fin rays, fish bones) were under investigation to reconstruct the habitat changes during the lifespan of a fishes life. Fish hard parts have the potential to serve as "life time recorder". Thus the spatial investigation of the elemental and isotopic composition can be used to monitor habitat changes with time. The spatially resolved data of hard tissues was collected by means of Laser Ablation Split Stream ICP-MS/MC ICP-MS. This work is accomplished within the scope of the project "CSI: TRACE YOUR FOOD".

17 CFR 2.2 - Authority to affix seal.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Authority to affix seal. 2.2 Section 2.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFFICIAL SEAL § 2.2 Authority to affix seal. (a) The following officials of the Commodity Futures Trading Commission are...

17 CFR 2.2 - Authority to affix seal.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Authority to affix seal. 2.2 Section 2.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION OFFICIAL SEAL § 2.2 Authority to affix seal. (a) The following officials of the Commodity Futures Trading Commission are...

29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

Code of Federal Regulations, 2011 CFR

2011-07-01

... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Agricultural Or Horticultural Commodities § 780.112 General meaning of “agriculture or horticultural commodities.” Section 3(f) of the Act defines as...

29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Agricultural Or Horticultural Commodities § 780.112 General meaning of “agriculture or horticultural commodities.” Section 3(f) of the Act defines as...

29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

Code of Federal Regulations, 2013 CFR

2013-07-01

... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Agricultural Or Horticultural Commodities § 780.112 General meaning of “agriculture or horticultural commodities.” Section 3(f) of the Act defines as...

29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

Code of Federal Regulations, 2014 CFR

2014-07-01

... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Agricultural Or Horticultural Commodities § 780.112 General meaning of “agriculture or horticultural commodities.” Section 3(f) of the Act defines as...

29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

Code of Federal Regulations, 2012 CFR

2012-07-01

... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT General Scope of Agriculture Agricultural Or Horticultural Commodities § 780.112 General meaning of “agriculture or horticultural commodities.” Section 3(f) of the Act defines as...

22 CFR 228.11 - Source and origin of commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Source and origin of commodities. 228.11 Section 228.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND... Commodity Procurement Transactions for USAID Financing § 228.11 Source and origin of commodities. (a) The...

17 CFR 1.49 - Denomination of customer funds and location of depositories.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Denomination of customer funds and location of depositories. 1.49 Section 1.49 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Miscellaneous § 1.49 Denomination...

17 CFR Appendix B to Part 190 - Special Bankruptcy Distributions

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Special Bankruptcy Distributions B Appendix B to Part 190 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... purposes of this distributional rule, XM accounts will be deemed to be commodity interest accounts and...

31 CFR 560.533 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2013 CFR

2013-07-01

... commodities, medicine, and medical devices. 560.533 Section 560.533 Money and Finance: Treasury Regulations... Policy § 560.533 Brokering sales of agricultural commodities, medicine, and medical devices. (a) General... of agricultural commodities, medicine, and medical devices, provided that the sale and exportation or...

31 CFR 538.526 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2011 CFR

2011-07-01

... commodities, medicine, and medical devices. 538.526 Section 538.526 Money and Finance: Treasury Regulations... Brokering sales of agricultural commodities, medicine, and medical devices. (a) General license for... agricultural commodities, medicine, and medical devices to the Government of Sudan, to any individual or entity...

31 CFR 560.533 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2014 CFR

2014-07-01

... commodities, medicine, and medical devices. 560.533 Section 560.533 Money and Finance: Treasury Regulations... Policy § 560.533 Brokering sales of agricultural commodities, medicine, and medical devices. (a) General... agricultural commodities, medicine, and medical devices, provided that the sale and exportation or...

31 CFR 538.526 - Brokering sales of agricultural commodities, medicine, and medical devices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... commodities, medicine, and medical devices. 538.526 Section 538.526 Money and Finance: Treasury Regulations... Brokering sales of agricultural commodities, medicine, and medical devices. (a) General license for... agricultural commodities, medicine, and medical devices to the Government of Sudan, to any individual or entity...

31 CFR 560.530 - Commercial sales, exportation, and reexportation of agricultural commodities, medicine, and...

Code of Federal Regulations, 2014 CFR

2014-07-01

... reexportation of agricultural commodities, medicine, and medical devices. 560.530 Section 560.530 Money and... commodities, medicine, and medical devices. (a)(1) One-year license requirement. (i) The exportation or reexportation of agricultural commodities, medicine, and medical devices that are not covered by the general...

17 CFR 4.12 - Exemption from provisions of part 4.

Code of Federal Regulations, 2010 CFR

2010-04-01

... part 4. 4.12 Section 4.12 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... said Act; (B) Will generally and routinely engage in the buying and selling of securities and securities derived instruments; (C) Will not enter into commodity futures and commodity options contracts for...

31 CFR 560.526 - Commodities trading and related transactions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Commodities trading and related... Licenses, Authorizations and Statements of Licensing Policy § 560.526 Commodities trading and related transactions. (a) Trading in Iranian-origin commodities. With respect to § 560.206, specific licenses may be...

75 FR 44890 - Operation, in the Ordinary Course, of a Commodity Broker in Bankruptcy

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... of the customers of such commodity broker, under appropriate circumstances, as determined by the... contracts on behalf of the customers of such commodity broker (the ``Notice'').\\1\\ The proposed rule stated... customer accounts are handled, under appropriate circumstances, in a commodity broker bankruptcy, which may...

7 CFR 17.5 - Contracts between commodity suppliers and importers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... officers and a description of the firm's experience as an exporter of U.S. agricultural commodities. Copies... under this part and the purchase authorization. (3) If, at the time the commodity supplier reports the... requirements unless otherwise specified in the purchase authorization. (1) Commodity contracts between...

17 CFR 31.6 - Registration of leverage commodities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... commodity's economic value and how such amendments might affect the ability of leverage customers making or... a change in the economic value of such commodities and, if so, quantify the extent of such changes... the ability of leverage customers electing to make or take delivery of the commodity at an economic...

31 CFR 560.526 - Commodities trading and related transactions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Commodities trading and related... Licenses, Authorizations and Statements of Licensing Policy § 560.526 Commodities trading and related transactions. (a) Trading in Iranian-origin commodities. With respect to § 560.206, specific licenses may be...

7 CFR 1488.9a - Evidence of export for commodities delivered before export.

Code of Federal Regulations, 2013 CFR

2013-01-01

... COMMODITIES Financing of Export Sales of Agricultural Commodities From Private Stocks Under CCC Export Credit... financial period is 12 months or less, the exporter shall furnish a certification to the Treasurer, CCC... Assistant Treasurer, CCC, certifying that the commodities have been exported. The certification must include...

7 CFR 1488.9a - Evidence of export for commodities delivered before export.

Code of Federal Regulations, 2012 CFR

2012-01-01

... COMMODITIES Financing of Export Sales of Agricultural Commodities From Private Stocks Under CCC Export Credit... financial period is 12 months or less, the exporter shall furnish a certification to the Treasurer, CCC... Assistant Treasurer, CCC, certifying that the commodities have been exported. The certification must include...

7 CFR 1488.9a - Evidence of export for commodities delivered before export.

Code of Federal Regulations, 2014 CFR

2014-01-01

... COMMODITIES Financing of Export Sales of Agricultural Commodities From Private Stocks Under CCC Export Credit... financial period is 12 months or less, the exporter shall furnish a certification to the Treasurer, CCC... Assistant Treasurer, CCC, certifying that the commodities have been exported. The certification must include...

' Self-organization' processes in proton and deuteron mixtures in open-chain hydrogen bond systems: polarization IR spectra of 4-mercaptopyridine crystals

NASA Astrophysics Data System (ADS)

Flakus, Henryk T.; Tyl, Aleksandra; Jones, Peter G.

2002-01-01

This paper is devoted to IR spectroscopic studies in polarized light of 4-mercaptopyridine (4-MPD) hydrogen-bonded crystals. These studies were preceded by determination of the 4-mercaptopyridine X-ray structure. Polarization spectra of 4-mercaptopyridine crystals were measured in the frequency ranges of νN-H and νN-D bands at room temperature, and also at the temperature of liquid nitrogen, for the two different crystalline faces: ' bc' and ' ac'. When investigating ' residual' νN-H band shapes for crystals that were diluted by deuterium, strong dichroic effects in the spectra were still observed, providing evidence for the existence in the hydrogen bond chains of domains containing exclusively protons or deuterons. This phenomenon proves the existence of a new kind of H/D isotopic effects in open chain hydrogen bond systems, namely ' self-organization' effects. Such effects, however, were not observed for other open chain hydrogen bond systems, e.g. alcohol crystals. Solid-state spectra of 4-mercaptopyridine were quantitatively interpreted, along with the strong polarization and the isotopic effects, when based on the ' strong-coupling' theory for linearly arranged hydrogen bond dimers.

School Meal Programs: More Systematic Development of Specifications Could Improve the Safety of Foods Purchased through USDA's Commodity Program. Report to the Ranking Member, Committee on Education and the Workforce, House of Representatives. GAO-11-376

ERIC Educational Resources Information Center

Shames, Lisa

2011-01-01

Through its commodity program, the U.S. Department of Agriculture (USDA) provides commodity foods at no cost to schools taking part in the national school meals programs. Commodities include raw ground beef, cheese, poultry, and fresh produce. Like federal food safety agencies, the commodity program has taken steps designed to reduce microbial…

Child mortality, commodity price volatility and the resource curse.

PubMed

Makhlouf, Yousef; Kellard, Neil M; Vinogradov, Dmitri

2017-04-01

Given many developing economies depend on primary commodities, the fluctuations of commodity prices may imply significant effects for the wellbeing of children. To investigate, this paper examines the relationship between child mortality and commodity price movements as reflected by country-specific commodity terms-of-trade. Employing a panel of 69 low and lower-middle income countries over the period 1970-2010, we show that commodity terms-of-trade volatility increases child mortality in highly commodity-dependent importers suggesting a type of 'scarce' resource curse. Strikingly however, good institutions appear able to mitigate the negative impact of volatility. The paper concludes by highlighting this tripartite relationship between child mortality, volatility and good institutions and posits that an effective approach to improving child wellbeing in low to lower-middle income countries will combine hedging, import diversification and improvement of institutional quality. Copyright © 2017. Published by Elsevier Ltd.

17 CFR 190.05 - Making and taking delivery on commodity contracts.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Making and taking delivery on... COMMISSION BANKRUPTCY § 190.05 Making and taking delivery on commodity contracts. (a) General. (1) In the..., which: (1) Permit the making and taking of delivery to fulfill a commodity futures contract for a...

17 CFR 32.1 - Scope of part 32; definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... OF COMMODITY OPTION TRANSACTIONS § 32.1 Scope of part 32; definitions. (a) Scope. The provisions of... commodity option transactions, shall apply to all commodity option transactions except for commodity option transactions conducted or executed on or subject to the rules of a contract market, or a foreign board of trade...

17 CFR 1.46 - Application and closing out of offsetting long and short positions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Application and closing out of offsetting long and short positions. 1.46 Section 1.46 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Miscellaneous § 1.46 Application...

31 CFR 538.525 - Payment for and financing of commercial sales of agricultural commodities, medicine, and medical...

Code of Federal Regulations, 2010 CFR

2010-07-01

... commercial sales of agricultural commodities, medicine, and medical equipment. 538.525 Section 538.525 Money... commodities, medicine, and medical equipment. (a) General license for payment terms. The following payment terms for sales, pursuant to § 538.523(a)(1), of agricultural commodities and products, medicine, and...

31 CFR 560.532 - Payment for and financing of exports and reexports of agricultural commodities, medicine, and...

Code of Federal Regulations, 2011 CFR

2011-07-01

... and reexports of agricultural commodities, medicine, and medical devices. 560.532 Section 560.532... commodities, medicine, and medical devices. (a) General license for payment terms. The following payment terms for sales of agricultural commodities and products, medicine, and medical equipment pursuant to §§ 560...

31 CFR 560.532 - Payment for and financing of exports and reexports of agricultural commodities, medicine, and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... and reexports of agricultural commodities, medicine, and medical devices. 560.532 Section 560.532... commodities, medicine, and medical devices. (a) General license for payment terms. The following payment terms for sales of agricultural commodities and products, medicine, and medical equipment pursuant to §§ 560...

31 CFR 538.525 - Payment for and financing of commercial sales of agricultural commodities, medicine, and medical...

Code of Federal Regulations, 2011 CFR

2011-07-01

... commercial sales of agricultural commodities, medicine, and medical equipment. 538.525 Section 538.525 Money... commodities, medicine, and medical equipment. (a) General license for payment terms. The following payment terms for sales, pursuant to § 538.523(a)(1), of agricultural commodities and products, medicine, and...

22 CFR 201.63 - Maximum prices for commodities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... actually incurred in moving the commodities supplied from the point of purchase to a position alongside or... between those points. (g) Commodity price subject to escalation. If a purchase contract contains a price.... prevailing market price—U.S. source. The purchase price for a commodity, the source of which is the United...

49 CFR 1248.1 - Freight commodity statistics.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 9 2011-10-01 2011-10-01 false Freight commodity statistics. 1248.1 Section 1248... STATISTICS § 1248.1 Freight commodity statistics. All class I railroads, as described in § 1240.1 of this... statistics on the basis of the commodity codes named in § 1248.101. Carriers shall report quarterly on the...

17 CFR 1.39 - Simultaneous buying and selling orders of different principals; execution of, for and between...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Simultaneous buying and... Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Recordkeeping § 1.39 Simultaneous buying and selling orders of different principals...

49 CFR 1248.1 - Freight commodity statistics.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Freight commodity statistics. 1248.1 Section 1248... STATISTICS § 1248.1 Freight commodity statistics. All class I railroads, as described in § 1240.1 of this... statistics on the basis of the commodity codes named in § 1248.101. Carriers shall report quarterly on the...

Highly conformationally constrained halogenated 6-spiroepoxypenicillins as probes for the bioactive side-chain conformation of benzylpenicillin

NASA Astrophysics Data System (ADS)

Shute, Richard E.; Jackson, David E.; Bycroft, Barrie W.

1989-06-01

The halogenated 6-spiroepoxypenicillins are a series of novel semisynthetic β-lactam compounds with highly conformationally restricted side chains incorporating an epoxide. Their biological activity profiles depend crucially on the configuration at position C-3 of that epoxide. In derivatives with aromatic-containing side chains, e.g., anilide, the 3 R-compounds possess notable Gram-positive antibacterial activity and potent β-lactamase inhibitory properties. The comparable 3S-compounds are antibacterially inactive, but retain β-lactamase inhibitory activity. Using the molecular simulation programs COSMIC and ASTRAL, we attempted to map a putative, lipophilic accessory binding site on the PBPs that must interact with the side-chain aromatic residue. Comparative computer-assisted modelling of the 3 R, and 3 S-anilides, along with benzylpenicillin, indicated that the available conformational space at room temperature for the side chains of the 3 R and the 3 S-anilides was mutually exclusive. The conformational space for the more flexible benzylpenicillin could accommodate the side chains of both the constrained penicillin derivatives. By a combination of van der Waals surface calculations and a pharmacophoric distance approach, closely coincident conformers of the 3 R-anilide and benzylpenicillin were identified. These conformers must be related to the antibacterial, `bioactive' conformer for the classical β-lactam antibiotics. From these proposed bioactive conformations, a model for the binding of benzylpenicillin to the PBPs relating the three-dimensional arrangement of a putative lipophilic S2-subsite, specific for the side-chain aromatic moiety, and the 3 α-carboxylate functionality is presented.

Multinetwork of international trade: A commodity-specific analysis

NASA Astrophysics Data System (ADS)

Barigozzi, Matteo; Fagiolo, Giorgio; Garlaschelli, Diego

2010-04-01

We study the topological properties of the multinetwork of commodity-specific trade relations among world countries over the 1992-2003 period, comparing them with those of the aggregate-trade network, known in the literature as the international-trade network (ITN). We show that link-weight distributions of commodity-specific networks are extremely heterogeneous and (quasi) log normality of aggregate link-weight distribution is generated as a sheer outcome of aggregation. Commodity-specific networks also display average connectivity, clustering, and centrality levels very different from their aggregate counterpart. We also find that ITN complete connectivity is mainly achieved through the presence of many weak links that keep commodity-specific networks together and that the correlation structure existing between topological statistics within each single network is fairly robust and mimics that of the aggregate network. Finally, we employ cross-commodity correlations between link weights to build hierarchies of commodities. Our results suggest that on the top of a relatively time-invariant “intrinsic” taxonomy (based on inherent between-commodity similarities), the roles played by different commodities in the ITN have become more and more dissimilar, possibly as the result of an increased trade specialization. Our approach is general and can be used to characterize any multinetwork emerging as a nontrivial aggregation of several interdependent layers.

Selective binding of carotenoids with a shorter conjugated chain to the LH2 antenna complex and those with a longer conjugated chain to the reaction center from Rubrivivax gelatinosus.

PubMed

Kakitani, Yoshinori; Fujii, Ritsuko; Hayakawa, Yoshihiro; Kurahashi, Masahiro; Koyama, Yasushi; Harada, Jiro; Shimada, Keizo

2007-06-19

Rubrivivax gelatinosus having both the spheroidene and spirilloxanthin biosynthetic pathways produces carotenoids (Cars) with a variety of conjugated chains, which consist of different numbers of conjugated double bonds (n), including the C=C (m) and C=O (o) bonds. When grown under anaerobic conditions, the wild type produces Cars for which n = m = 9-13, whereas under semiaerobic conditions, it additionally produces Cars for which n = m + o = 10 + 1, 13 + 1, and 13 + 2. On the other hand, a mutant, in which the latter pathway is genetically blocked, produces only Cars for which n = 9 and 10 under anaerobic conditions and n = 9, 10, and 10 + 1 under semianaerobic conditions. Those Cars that were extracted from the LH2 complex (LH2) and the reaction center (RC), isolated from the wild-type and the mutant Rvi. gelatinosus, were analyzed by HPLC, and their structures were determined by mass spectrometry and 1H NMR spectroscopy. The selective binding of Cars to those pigment-protein complexes has been characterized as follows. (1) Cars with a shorter conjugated chain are selectively bound to LH2 whereas Cars with a longer conjugated chain to the RC. (2) Shorter chain Cars with a hydroxyl group are bound to LH2 almost exclusively. This rule holds either in the absence or in the presence of the keto group. The natural selection of shorter chain Cars by LH2 and longer chain Cars by the RC is discussed, on the basis of the results now available, in relation to the light-harvesting and photoprotective functions of Cars.

Transmission and control of Salmonella in the pig feed chain: a conceptual model.

PubMed

Binter, Claudia; Straver, Judith Maria; Häggblom, Per; Bruggeman, Geert; Lindqvist, Per-Anders; Zentek, Jürgen; Andersson, Mats Gunnar

2011-03-01

Infected breeder pigs and contaminated feed represent potential sources of Salmonella introduction to fattening pig herds and may thereby cause human infections acquired via consumption of contaminated pork. Modelling approaches such as quantitative microbial risk assessment could improve the design of strategies for control and tracing of Salmonella in the feed chain. However, the construction of such models requires a thorough understanding of the dynamics of the feed chain, including production processes, microbial processes and transport logistics. The present article illustrates a conceptual model of Salmonella in the pig feed chain and explores the possibilities for quantitative modelling including identifying major gaps in data. Information was collected from peer-reviewed scientific journals, official documents and reports and by means of interviews with experts from authorities and the feed industry. Data on prevalence of Salmonella in different parts of the feed chain are difficult to compare as observed prevalence may be biased by variations in sampling procedures as well as limitations of the detection methods. There are almost no data on numbers of Salmonella in commodities of the feed chain, which often makes it difficult to evaluate risks, intervention strategies and sampling plans in a quantitative manner. Tracing the source of Salmonella contamination is hampered by the risk of cross-contamination as well as various mixing and partitioning events along the supply chain, which sometimes makes it impossible to trace the origin of a lot back to a batch or producer. Available information points to contaminated feed materials, animal vectors and persistent contamination of production environments as important sources of Salmonella in feed production. Technological procedures such as hydrothermal or acid treatment can be used to control Salmonella in feed production. However, a large fraction of pig feed is produced without decontamination procedures. Prevention of recontamination and control of moisture throughout the chain are thus critical factors for controlling Salmonella in feed production. To verify successful control it is necessary to have monitoring strategies able to detect low levels of Salmonella heterogeneously distributed in large volumes of feed and feed material in bulk. Experience from monitoring programs and research investigations indicates that sampling of dust and sweepings from control points along the production line is an efficient strategy to gain an indication of Salmonella contamination. Copyright © 2010 Elsevier B.V. All rights reserved.

Availability, prices and affordability of UN Commission's lifesaving medicines for reproductive and maternal health in Uganda.

PubMed

Kibira, Denis; Kitutu, Freddy Eric; Merrett, Gemma Buckland; Mantel-Teeuwisse, Aukje K

2017-01-01

Uganda was one of seven countries in which the United Nations Commission on Life Saving Commodities (UNCoLSC) initiative was implemented starting from 2013. A nationwide survey was conducted in 2015 to determine availability, prices and affordability of essential UNCoLSC maternal and reproductive health (MRH) commodities. The survey at health facilities in Uganda was conducted using an adapted version of the standardized methodology co-developed by World Health Organisation (WHO) and Health Action International (HAI). In this study, six maternal and reproductive health commodities, that were part of the UNCoLSC initiative, were studied in the public, private and mission health sectors. Median price ratios were calculated with Management Sciences for Health International Drug Price Indicator prices as reference. Maternal and reproductive health commodity stocks were reviewed from stock cards for their availability for a period of 6 months preceding the survey. Affordability was measured using wages of the lowest paid government worker. Overall none of the six maternal and reproductive commodities was found in the surveyed health facilities. Public sector had the highest availability (52%), followed by mission sector (36%) and then private sector had the least (30%). Stock outs ranged from 7 to 21 days in public sector; 2 to 23 days in private sector and 3 to 27 days in mission sector. During the survey, maternal health commodities were more available and had less number of stock out days than reproductive health commodities. Median price ratios (MPR) indicated that medicines and commodities were more expensive in Uganda compared to international reference prices. Furthermore, MRH medicines and commodities were more expensive and less affordable in private sector compared to mission sector. Access to MRH commodities is inadequate in Uganda. Maternal health commodities were more available, cheaper and thus more affordable than reproductive health commodities in the current study. Efforts should be undertaken by the Ministry of Health and stakeholders to improve availability, prices and affordability of MRH commodities in Uganda to ensure that sustainable Development Goals are met.

A multi-period distribution network design model under demand uncertainty

NASA Astrophysics Data System (ADS)

Tabrizi, Babak H.; Razmi, Jafar

2013-05-01

Supply chain management is taken into account as an inseparable component in satisfying customers' requirements. This paper deals with the distribution network design (DND) problem which is a critical issue in achieving supply chain accomplishments. A capable DND can guarantee the success of the entire network performance. However, there are many factors that can cause fluctuations in input data determining market treatment, with respect to short-term planning, on the one hand. On the other hand, network performance may be threatened by the changes that take place within practicing periods, with respect to long-term planning. Thus, in order to bring both kinds of changes under control, we considered a new multi-period, multi-commodity, multi-source DND problem in circumstances where the network encounters uncertain demands. The fuzzy logic is applied here as an efficient tool for controlling the potential customers' demand risk. The defuzzifying framework leads the practitioners and decision-makers to interact with the solution procedure continuously. The fuzzy model is then validated by a sensitivity analysis test, and a typical problem is solved in order to illustrate the implementation steps. Finally, the formulation is tested by some different-sized problems to show its total performance.

Mixotrophy and intraguild predation - dynamic consequences of shifts between food web motifs

NASA Astrophysics Data System (ADS)

Karnatak, Rajat; Wollrab, Sabine

2017-06-01

Mixotrophy is ubiquitous in microbial communities of aquatic systems with many flagellates being able to use autotroph as well as heterotroph pathways for energy acquisition. The usage of one over the other pathway is associated with resource availability and the coupling of alternative pathways has strong implications for system stability. We investigated the impact of dominance of different energy pathways related to relative resource availability on system dynamics in the setting of a tritrophic food web motif. This motif consists of a mixotroph feeding on a purely autotroph species while competing for a shared resource. In addition, the autotroph can use an additional exclusive food source. By changing the relative abundance of shared vs. exclusive food source, we shift the food web motif from an intraguild predation motif to a food chain motif. We analyzed the dependence of system dynamics on absolute and relative resource availability. In general, the system exhibits a transition from stable to oscillatory dynamics with increasing nutrient availability. However, this transition occurs at a much lower nutrient level for the food chain in comparison to the intraguild predation motif. A similar transition is also observed with variations in the relative abundance of food sources for a range of nutrient levels. We expect this shift in food web motifs to occur frequently in microbial communities and therefore the results from our study are highly relevant for natural systems.

Indole Localization in an Explicit Bilayer Revealed via Molecular Dynamics

NASA Astrophysics Data System (ADS)

Norman, Kristen

2005-11-01

It is well known that the amino-acid tryptophan is particularly stable in the interfacial region of biological membranes, and this preference is a property of the tryptophan side-chain. Analogues of this side-chain, such as indole, strongly localize in the interfacial region, especially near the glycerol moiety of the lipids in the bilayer. Using molecular dynamics calculations, we determine the potential of mean force (PMF) for indoles in the bilayer. We compare the calculated PMF for indole with that of benzene to show that exclusion from the center of the lipid bilayer does not occur in all aromatics, but is strong in indoles. We find three minima in the PMF. Indole is most stabilized near the glycerol moiety. A weaker binding location is found near the choline groups of the lipid molecules. An even weaker binding side is found near the center of the lipid hydrocarbon core. Comparisions between uncharged, weakly charged, and highly charged indoles demonstrate that the exclusion is caused by the charge distribution on the indole rather than the ``lipo-phobic'' effect. High temperature simulations are used to determine the relative contribution of enthalpy and entropy to indole localization. The orientation of indole is found to be largely charge independent and is a strong function of depth within the bilayer. We find good agreement between simulated SCD order parameters for indole and experimentally determined order parameters.

22 CFR 211.9 - Liability for loss damage or improper distribution of commodities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... sponsors may add to the value any provable costs they have incurred prior to delivery by the ocean carrier... TRANSFER OF FOOD COMMODITIES FOR FOOD USE IN DISASTER RELIEF, ECONOMIC DEVELOPMENT AND OTHER ASSISTANCE... or damage to commodities. (See paragraph (c)(2)(iii) of this section.) (B) The value of commodities...

22 CFR 211.9 - Liability for loss damage or improper distribution of commodities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... sponsors may add to the value any provable costs they have incurred prior to delivery by the ocean carrier... TRANSFER OF FOOD COMMODITIES FOR FOOD USE IN DISASTER RELIEF, ECONOMIC DEVELOPMENT AND OTHER ASSISTANCE... or damage to commodities. (See paragraph (c)(2)(iii) of this section.) (B) The value of commodities...

48 CFR 470.202 - Acquisition of commodities for United States Agency for International Development (USAID) programs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... to foreign destinations and related freight to transport such commodities under Title II of Public... respect to a commodity procurement or a freight procurement will specify that in the event an offer... offer if the acceptance of another offer for the commodity or freight, when combined with other offers...

48 CFR 470.202 - Acquisition of commodities for United States Agency for International Development (USAID) programs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... to foreign destinations and related freight to transport such commodities under Title II of Public... respect to a commodity procurement or a freight procurement will specify that in the event an offer... offer if the acceptance of another offer for the commodity or freight, when combined with other offers...

48 CFR 470.202 - Acquisition of commodities for United States Agency for International Development (USAID) programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... to foreign destinations and related freight to transport such commodities under Title II of Public... respect to a commodity procurement or a freight procurement will specify that in the event an offer... offer if the acceptance of another offer for the commodity or freight, when combined with other offers...

48 CFR 470.202 - Acquisition of commodities for United States Agency for International Development (USAID) programs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... to foreign destinations and related freight to transport such commodities under Title II of Public... respect to a commodity procurement or a freight procurement will specify that in the event an offer... offer if the acceptance of another offer for the commodity or freight, when combined with other offers...

Origin of Money: Dynamic Duality Between Necessity and Unnecessity

NASA Astrophysics Data System (ADS)

Tauchi, Yuka; Kamiura, Moto; Haruna, Taichi; Gunji, Yukio-Pegio

2008-10-01

We propose a mathematical model of economic agents to study origin of money. This multi-agent model is based on commodity theory of money, which says that a commodity used as money emerges from barter transaction. Each agent has a different value system which is given by a Heyting algebra, and exchanges one's commodities based on the value system. In each value system, necessity and unnecessity of commodities are expressed by some elements and their compliments on a Heyting Algebra. Moreover, the concept of the compliment is extended. Consequently, the duality of the necessity-unnecessity is weakened, and the exchanges of the commodities are promoted. The commodities which keeps being exchanged for a long time can correspond to money.

Establishing a regulatory value chain model: An innovative approach to strengthening medicines regulatory systems in resource-constrained settings.

PubMed

Chahal, Harinder Singh; Kashfipour, Farrah; Susko, Matt; Feachem, Neelam Sekhri; Boyle, Colin

2016-05-01

Medicines Regulatory Authorities (MRAs) are an essential part of national health systems and are charged with protecting and promoting public health through regulation of medicines. However, MRAs in resource-constrained settings often struggle to provide effective oversight of market entry and use of health commodities. This paper proposes a regulatory value chain model (RVCM) that policymakers and regulators can use as a conceptual framework to guide investments aimed at strengthening regulatory systems. The RVCM incorporates nine core functions of MRAs into five modules: (i) clear guidelines and requirements; (ii) control of clinical trials; (iii) market authorization of medical products; (iv) pre-market quality control; and (v) post-market activities. Application of the RVCM allows national stakeholders to identify and prioritize investments according to where they can add the most value to the regulatory process. Depending on the economy, capacity, and needs of a country, some functions can be elevated to a regional or supranational level, while others can be maintained at the national level. In contrast to a "one size fits all" approach to regulation in which each country manages the full regulatory process at the national level, the RVCM encourages leveraging the expertise and capabilities of other MRAs where shared processes strengthen regulation. This value chain approach provides a framework for policymakers to maximize investment impact while striving to reach the goal of safe, affordable, and rapidly accessible medicines for all.

Thermodynamics and mechanics of stretch-induced crystallization in rubbers

NASA Astrophysics Data System (ADS)

Guo, Qiang; Zaïri, Fahmi; Guo, Xinglin

2018-05-01

The aim of the present paper is to provide a quantitative prediction of the stretch-induced crystallization in natural rubber, the exclusive reason for its history-dependent thermomechanical features. A constitutive model based on a micromechanism inspired molecular chain approach is formulated within the context of the thermodynamic framework. The molecular configuration of the partially crystallized single chain is analyzed and calculated by means of some statistical mechanical methods. The random thermal oscillation of the crystal orientation, considered as a continuous random variable, is treated by means of a representative angle. The physical expression of the chain free energy is derived according to a two-step strategy by separating crystallization and stretching. This strategy ensures that the stretch-induced part of the thermodynamic crystallization force is null at the initial instant and allows, without any additional constraint, the formulation of a simple linear relationship for the crystallinity evolution law. The model contains very few physically interpretable material constants to simulate the complex mechanism: two chain-scale constants, one crystallinity kinetics constant, three thermodynamic constants related to the newly formed crystallites, and a function controlling the crystal orientation with respect to the chain. The model is used to discuss some important aspects of the micromechanism and the macroresponse under the equilibrium state and the nonequilibrium state involved during stretching and recovery, and continuous relaxation.

Involvement of triacylglycerol in the metabolism of fatty acids by cultured neuroblastoma and glioma cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, H.W.; Clarke, J.T.; Spence, M.W.

1982-12-01

The metabolism (chain elongation, desaturation, and incorporation into complex lipids) of thirteen different radiolabeled fatty acids and acetate was examined in N1E-115 neuroblastoma and C-6 glioma cell lines in culture. During 6-hr incubations, all fatty acids were extensively (14-80%) esterified to complex lipids, mainly choline phosphoglycerides and triacylglycerol. With trienoic and tetraenoic substrates, inositol and ethanolamine phosphoglycerides also contained up to 30% of the labeled fatty acids; plasmalogen contained up to half of the label in the ethanolamine phosphoglyceride fraction of neuroblastoma cells. Chain elongation and delta 9, delta 6, and delta 5 desaturation occurred in both cell lines; deltamore » 4 desaturation was not observed. Seemingly anomalous utilization of arachidic acid and some selectivity based on the geometric configuration of double bonds was observed. These studies indicate that these cell lines are capable of modulating cellular membrane composition by a combination of selective exclusion and removal of inappropriate acyl chains and of modification of other acyl chains by desaturation and chain elongation. The time courses and patterns of modification and incorporation of exogenous substrates into phospholipids and triacylglycerol suggest that exogenous unsaturated fatty acid may be incorporated into triacylglycerol and later released for further metabolism and incorporation into phospholipids. This supports a role for triacylglycerol in the synthesis of membrane complex lipids in cell lines derived from neural tissue.« less

Regio- and Stereospecific Conversion of 4-Alkylphenols by the Covalent Flavoprotein Vanillyl-Alcohol Oxidase

PubMed Central

van den Heuvel, Robert H. H.; Fraaije, Marco W.; Laane, Colja; van Berkel, Willem J. H.

1998-01-01

The regio- and stereospecific conversion of prochiral 4-alkylphenols by the covalent flavoprotein vanillyl-alcohol oxidase was investigated. The enzyme was active, with 4-alkylphenols bearing aliphatic side chains of up to seven carbon atoms. Optimal catalytic efficiency occurred with 4-ethylphenol and 4-n-propylphenols. These short-chain 4-alkylphenols are stereoselectively hydroxylated to the corresponding (R)-1-(4′-hydroxyphenyl)alcohols (F. P. Drijfhout, M. W. Fraaije, H. Jongejan, W. J. H. van Berkel, and M. C. R. Franssen, Biotechnol. Bioeng. 59:171–177, 1998). (S)-1-(4′-Hydroxyphenyl)ethanol was found to be a far better substrate than (R)-1-(4′-hydroxyphenyl)ethanol, explaining why during the enzymatic conversion of 4-ethylphenol nearly no 4-hydroxyacetophenone is formed. Medium-chain 4-alkylphenols were exclusively converted by vanillyl-alcohol oxidase to the corresponding 1-(4′-hydroxyphenyl)alkenes. The relative cis-trans stereochemistry of these reactions was strongly dependent on the nature of the alkyl side chain. The enzymatic conversion of 4-sec-butylphenol resulted in two (4′-hydroxyphenyl)-sec-butene isomers with identical masses but different fragmentation patterns. We conclude that the water accessibility of the enzyme active site and the orientation of the hydrophobic alkyl side chain of the substrate are of major importance in determining the regiospecific and stereochemical outcome of vanillyl-alcohol oxidase-mediated conversions of 4-alkylphenols. PMID:9791114

Commodity aspirations in Easterlin's relative income theory of fertility.

PubMed

Ahlburg, D A

1984-01-01

This paper presents the preference ordering that underlies Easterlin's relative income theory of fertility. Commodity aspirations are a key component of the theory and the paper explores how the introduction of commodity aspirations into the utility function affects the consumption of commodities and bearing of children. The formation and empirical specification of commodity aspirations are also discussed. Commodity aspirations are formed by the material environment experienced during childhood and are primarily a function of parental income. Easterlin, Leibenstein and Ben-Porath argus that it is the parental consumption or standard of living that determines the child's testes or aspirations. It is the parents' spending on themseleves rather than total parental income that can be used as a proxy for the child's commodity aspirations. Bagozzi and Van Loo identify 4 significant contributions made by Easterlinhs theory of fertility. They cite his stress on potential income flow through time as being pertinent to household decision making; tastes being an explicit determinant of fertility; background charactersticis and norms as to standards of child care and family size affecting fertility indirectly through tastes rather than directly; and the fact that relative income has an effect on fertility in addition to the influence of the absolute level of income. The number of children demanded is a negative function of commodity aspirations, as is the utility of the family. Studies of the demand for commodities and children should include data on parental resources.

17 CFR 15.00 - Definitions of terms used in parts 15 to 21 of this chapter.

Code of Federal Regulations, 2011 CFR

2011-04-01

... chapter. As used in parts 15 to 21 of this chapter: (a) Cash or Spot, when used in connection with any..., commodity pool or partnership account. (g) Discretionary account means a commodity futures or commodity... spot, single or in all-months fixed in § 150.2 of this chapter for the particular commodity and...

Methodology and User Guide for the Food Intakes Converted to Retail Commodities Databases: CSFII 1994-1996 and 1998; NHANES 1999-2000; WWEIA, NHANES 2001-2002

USDA-ARS?s Scientific Manuscript database

The purpose for developing the Food Intakes Converted to Retail Commodities Database (FICRCD) is to convert foods consumed in the national dietary surveys, 1994-2002, to respective amounts of retail-level food commodities. Food commodities are defined as those available for purchase in retail store...

17 CFR 1.1 - Fraud in or in connection with transactions in foreign currency subject to the Commodity Exchange...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Fraud in or in connection with... Securities Exchanges COMMODITY FUTURES TRADING COMMISSION GENERAL REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.1 Fraud in or in connection with transactions in foreign currency subject to the...

Construction Method of Display Proposal for Commodities in Sales Promotion by Genetic Algorithm

NASA Astrophysics Data System (ADS)

Yumoto, Masaki

In a sales promotion task, wholesaler prepares and presents the display proposal for commodities in order to negotiate with retailer's buyers what commodities they should sell. For automating the sales promotion tasks, the proposal has to be constructed according to the target retailer's buyer. However, it is difficult to construct the proposal suitable for the target retail store because of too much combination of commodities. This paper proposes a construction method by Genetic algorithm (GA). The proposed method represents initial display proposals for commodities with genes, improve ones with the evaluation value by GA, and rearrange one with the highest evaluation value according to the classification of commodity. Through practical experiment, we can confirm that display proposal by the proposed method is similar with the one constructed by a wholesaler.

Radiation ecology issues associated with murine rodents and shrews in the Chernobyl exclusion zone.

PubMed

Gaschak, Sergey P; Maklyuk, Yulia A; Maksimenko, Andrey M; Bondarkov, Mikhail D; Jannik, G Timothy; Farfán, Eduardo B

2011-10-01

This article describes major studies performed by the Chernobyl Center's International Radioecology Laboratory (Slavutich, Ukraine) on radioecology of murine rodents and shrews inhabiting the Chernobyl Exclusion Zone. The article addresses the long-term (1986-2005) and seasonal dynamics of radioactive contamination of animals and reviews interspecies differences in radionuclide accumulations and factors affecting the radionuclide accumulations. It is shown that bioavailability of radionuclides in the "soil-to-plant" chain and a trophic specialization of animals play key roles in determining their actual contamination levels. The total absorbed dose rates in small mammals significantly reduced during the years following the Chernobyl Nuclear Power Plant accident. In 1986, the absorbed dose rate reached 1.3-6.0 Gy h(-1) in the central areas of the Chernobyl Exclusion Zone (the "Red Forest"). In 1988 and 1990, the total absorbed dose rates were 1.3 and 0.42 Gy h(-1), respectively. In 1995, 2000, and 2005, according to the present study, the total absorbed dose rates rarely exceeded 0.00023, 0.00018, and 0.00015 Gy h(-1), respectively. Contributions of individual radiation sources into the total absorbed dose are described.

Event-by-Event Study of Space-Time Dynamics in Flux-Tube Fragmentation

DOE PAGES

Wong, Cheuk-Yin

2017-05-25

In the semi-classical description of the flux-tube fragmentation process for hadron production and hadronization in high-energymore » $e^+e^-$ annihilations and $pp$ collisions, the rapidity-space-time ordering and the local conservation laws of charge, flavor, and momentum provide a set of powerful tools that may allow the reconstruction of the space-time dynamics of quarks and mesons in exclusive measurements of produced hadrons, on an event-by-event basis. We propose procedures to reconstruct the space-time dynamics from event-by-event exclusive hadron data to exhibit explicitly the ordered chain of hadrons produced in a flux tube fragmentation. As a supplementary tool, we infer the average space-time coordinates of the $q$-$$\\bar q$$ pair production vertices from the $$\\pi^-$$ rapidity distribution data obtained by the NA61/SHINE Collaboration in $pp$ collisions at $$\\sqrt{s}$$ = 6.3 to 17.3 GeV.« less

Separation and characterization of potato lipid acylhydrolases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasson, E.P.; Laties, G.G.

1976-02-01

Three distinct potato (Solanum tuberosum) lipid acyl-hydrolases have been isolated and characterized. Nonfluorescent esters of the fluorescent alcohols, N-methylindoxyl and N-methylumbelliferone, have been used as convenient substrates for lipid acyl-hydrolase estimation. Enzyme I has been shown to be a neutral lipase which favors glyceryl triolein over the di- and monoolein, which shows no activity with phospho- and galactolipids and which favors long chain fatty acid esters of N-methylindoxyl over the butyrate ester. Enzyme II, while attacking glyceryl mono- and diolein, as well as favoring the butyrate ester of N-methylindoxyl over the myristate ester, is basically a phospholipid and galactolipid acyl-hydrolase.more » Enzyme III may reasonably be considered an esterase, since it hydrolyzes glyceryl monoolein exclusively among the neutral lipids, shows minimal activity on phospho- and galactolipids, and hydrolyzes N-methylindoxylbutyrate exclusively compared with N-methylindoxylmyristate.« less

Balancing size exclusion and adsorption of polymers in nanopores

NASA Astrophysics Data System (ADS)

Kim, Won; Ryu, Chang Y.

2006-03-01

The liquid chromatography at critical condition (LCCC) presents the condition, at which the size exclusion and adsorption of polymer chains are balanced upon interactions with nanoporous substrates. In this study, we investigate how the polymer interactions with nanopores are affected by the solvent quality and nanopore size. Specifically, we measure the retention times of monodisperse polystyrenes in C18-bonded nanoporous silica column as a function of molecular weight, when a mixed solvent of methylene chloride and acetonitrile are used as elutent. C18-bonded silica particles with 70, 100, and 250 A pore size are used as a stationary phase to study how the transition from SEC-like to IC-like retention behavior depends on the condition of temperature and solvent composition. To locate the LCCC at various nanopore sizes, the temperature and solvent composition have been varied from 0 to 60 C and from 51 to 62 v/v% of methylene chloride, respectively.

Event-by-Event Study of Space-Time Dynamics in Flux-Tube Fragmentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wong, Cheuk-Yin

In the semi-classical description of the flux-tube fragmentation process for hadron production and hadronization in high-energymore » $e^+e^-$ annihilations and $pp$ collisions, the rapidity-space-time ordering and the local conservation laws of charge, flavor, and momentum provide a set of powerful tools that may allow the reconstruction of the space-time dynamics of quarks and mesons in exclusive measurements of produced hadrons, on an event-by-event basis. We propose procedures to reconstruct the space-time dynamics from event-by-event exclusive hadron data to exhibit explicitly the ordered chain of hadrons produced in a flux tube fragmentation. As a supplementary tool, we infer the average space-time coordinates of the $q$-$$\\bar q$$ pair production vertices from the $$\\pi^-$$ rapidity distribution data obtained by the NA61/SHINE Collaboration in $pp$ collisions at $$\\sqrt{s}$$ = 6.3 to 17.3 GeV.« less

Low Fermentation pH Is a Trigger to Alcohol Production, but a Killer to Chain Elongation.

PubMed

Ganigué, Ramon; Sánchez-Paredes, Patricia; Bañeras, Lluis; Colprim, Jesús

2016-01-01

Gasification of organic wastes coupled to syngas fermentation allows the recovery of carbon in the form of commodity chemicals, such as carboxylates and biofuels. Acetogenic bacteria ferment syngas to mainly two-carbon compounds, although a few strains can also synthesize four-, and six-carbon molecules. In general, longer carbon chain products have a higher biotechnological (and commercial) value due to their higher energy content and their lower water solubility. However, de-novo synthesis of medium-chain products from syngas is quite uncommon in acetogenic bacteria. An alternative to de-novo synthesis is bioproduction of short-chain products (C2 and C4), and their subsequent elongation to C4, C6, or C8 through reversed β-oxidation metabolism. This two-step synergistic approach has been successfully applied for the production of up to C8 compounds, although the accumulation of alcohols in these mixed cultures remained below detection limits. The present work investigates the production of higher alcohols from syngas by open mixed cultures (OMC). A syngas-fermenting community was enriched from sludge of an anaerobic digester for a period of 109 days in a lab-scale reactor. At the end of this period, stable production of ethanol and butanol was obtained. C6 compounds were only transiently produced at the beginning of the enrichment phase, during which Clostridium kluyveri, a bacterium able to carry out carbon chain elongation, was detected in the community. Further experiments showed pH as a critical parameter to maintain chain elongation activity in the co-culture. Production of C6 compounds was recovered by preventing fermentation pH to decrease below pH 4.5-5. Finally, experiments showed maximal production of C6 compounds (0.8 g/L) and alcohols (1.7 g/L of ethanol, 1.1 g/L of butanol, and 0.6 g/L of hexanol) at pH 4.8. In conclusion, low fermentation pH is critical for the production of alcohols, although detrimental to C. kluyveri. Fine control of fermentation pH to final values around 4.8 could allow sustained production of higher alcohols.

17 CFR 3.3 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false [Reserved] 3.3 Section 3.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGISTRATION Registration § 3.3 [Reserved] ...

17 CFR 3.3 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false [Reserved] 3.3 Section 3.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION REGISTRATION Registration § 3.3 [Reserved] ...

Profitability of Using Forecasting Techniques in the Commodities Market

DTIC Science & Technology

1985-12-01

12 II. THE NATURE OF THE COMMODITIES MARKET . . . . . 13 A. FUTURES TRADING . . . . ...... . . . . . 13 B. HEDGING IN THE COMMODITIES...1984 WHEAT ........ . . . ............... . 74 j7 4’ -- S . LIST OF FIGURES 2.1 Example of a Perfect Hedge . . . . . . . . . . . . . 17 3.1 Iterative...actually results in a commodity delivery [Ref. 31. The majority of these transactions are * taken up by hedgers and speculators. B. HEDGING IN THE

Primary Commodity Dependency: A Limiting Factor for Achieving Democracy

DTIC Science & Technology

2010-03-24

two ~gricultural crops, minerals, petroleum, or fisheries can be considered primary commodity dependent. Tea, coffee, and cocoa ; peanuts and cotton...Rostow’s Development Model Pre-conditions for take-off mass consumption democracy. In 1960s, economists, associated democratization to a developmental...Commodities can be renewable or non-renewable. Petroleum, diamonds, cocoa , bananas, coffee, and timber are just a few of the commodities that have

7 CFR 247.28 - Storage and inventory of commodities.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.28 Storage and... must provide for storage of commodities that protects them from theft, spoilage, damage or destruction...

7 CFR 247.28 - Storage and inventory of commodities.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.28 Storage and... must provide for storage of commodities that protects them from theft, spoilage, damage or destruction...

7 CFR 247.28 - Storage and inventory of commodities.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.28 Storage and... must provide for storage of commodities that protects them from theft, spoilage, damage or destruction...

7 CFR 247.28 - Storage and inventory of commodities.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.28 Storage and... must provide for storage of commodities that protects them from theft, spoilage, damage or destruction...

7 CFR 247.28 - Storage and inventory of commodities.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS COMMODITY SUPPLEMENTAL FOOD PROGRAM § 247.28 Storage and... must provide for storage of commodities that protects them from theft, spoilage, damage or destruction...

33 CFR 402.6 - Volume Rebate Incentive program

Code of Federal Regulations, 2010 CFR

2010-07-01

... defined under the Manager's commodity classification, for which a Volume Rebate is sought, the origin or... already move the commodity, as defined under the Manager's commodity classification, through the Seaway at...

33 CFR 402.6 - Volume Rebate Incentive program

Code of Federal Regulations, 2011 CFR

2011-07-01

... defined under the Manager's commodity classification, for which a Volume Rebate is sought, the origin or... already move the commodity, as defined under the Manager's commodity classification, through the Seaway at...

7 CFR 1421.112 - Foreclosure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... effected without removing the commodity from storage. The commodity may be processed before sale and CCC may become the purchaser of the whole or any part of the commodity at either a public or private sale...

7 CFR 1421.112 - Foreclosure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... effected without removing the commodity from storage. The commodity may be processed before sale and CCC may become the purchaser of the whole or any part of the commodity at either a public or private sale...

7 CFR 253.10 - Commodity control, storage and distribution.

Code of Federal Regulations, 2010 CFR

2010-01-01

... recorded. (15) Posters are conspicuously displayed advising program participants to accept only those... commodities with the same or similar kind of commodities which are sound and in good condition. The State...

7 CFR 1499.8 - Entry and handling of commodities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... entry and transit. The participant shall store and maintain the donated commodities in good condition...) Banners, posters or other media informing the public of the name and source of the donated commodities...

41 CFR 51-6.13 - Replacement and similar commodities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT... desire to procure additional sizes, colors, or other variations of a commodity after the commodity is...

41 CFR 51-6.13 - Replacement and similar commodities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT... desire to procure additional sizes, colors, or other variations of a commodity after the commodity is...

41 CFR 51-6.13 - Replacement and similar commodities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT... desire to procure additional sizes, colors, or other variations of a commodity after the commodity is...

41 CFR 51-6.13 - Replacement and similar commodities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT... desire to procure additional sizes, colors, or other variations of a commodity after the commodity is...

41 CFR 51-6.13 - Replacement and similar commodities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED 6-PROCUREMENT... desire to procure additional sizes, colors, or other variations of a commodity after the commodity is...

Data Cubes Integration in Spatial OLAP for Agricultural Commodities

NASA Astrophysics Data System (ADS)

Putri, A. I.; Sitanggang, I. S.

2017-03-01

Ministry of Agriculture Indonesia collects data of agricultural commodities in Indonesia in the annual period. Agricultural commodities data include food crops, horticulture, plantations, and livestock. The data are available in the spreadsheet format. This study developed data cubes for food crops, plantations, and livestock using the galaxy schema of data warehouse and integrated the data cubes into the SOLAP Horticulture using SpagoBI. SOLAP is useful for data analysis and data visualization. The application displays agricultural commodities data in form of crosstab and chart. This study also developed the location intelligence module that visualizes agricultural commodities data on the map. The system was tested using the black box approach. The result showed that main functions including roll up, drill down, slice, dice, and pivot work properly. This application is expected to enable users to easily obtain data summaries of agricultural commodities.

Effects of Regulation and Technology on End Uses of Nonfuel Mineral Commodities in the United States

USGS Publications Warehouse

Matos, Grecia R.

2007-01-01

The regulatory system and advancement of technologies have shaped the end-use patterns of nonfuel minerals used in the United States. These factors affected the quantities and types of materials used by society. Environmental concerns and awareness of possible negative effects on public health prompted numerous regulations that have dramatically altered the use of commodities like arsenic, asbestos, lead, and mercury. While the selected commodities represent only a small portion of overall U.S. materials use, they have the potential for harmful effects on human health or the environment, which other commodities, like construction aggregates, do not normally have. The advancement of technology allowed for new uses of mineral materials in products like high-performance computers, telecommunications equipment, plasma and liquid-crystal display televisions and computer monitors, mobile telephones, and electronic devices, which have become mainstream products. These technologies altered the end-use pattern of mineral commodities like gallium, germanium, indium, and strontium. Human ingenuity and people?s demand for different and creative services increase the demand for new materials and industries while shifting the pattern of use of mineral commodities. The mineral commodities? end-use data are critical for the understanding of the magnitude and character of these flows, assessing their impact on the environment, and providing an early warning of potential problems in waste management of products containing these commodities. The knowledge of final disposition of the mineral commodity allows better decisions as to how regulation should be tailored.

Extrusion induced low-order starch matrices: Enzymic hydrolysis and structure.

PubMed

Zhang, Bin; Dhital, Sushil; Flanagan, Bernadine M; Luckman, Paul; Halley, Peter J; Gidley, Michael J

2015-12-10

Waxy, normal and highwaymen maize starches were extruded with water as sole plasticizer to achieve low-order starch matrices. Of the three starches, we found that only high-amylose extrudate showed lower digestion rate/extent than starches cooked in excess water. The ordered structure of high-amylose starches in cooked and extruded forms was similar, as judged by NMR, XRD and DSC techniques, but enzyme resistance was much greater for extruded forms. Size exclusion chromatography suggested that longer chains were involved in enzyme resistance. We propose that the local molecular density of packing of amylose chains can control the digestion kinetics rather than just crystallinity, with the principle being that density sufficient to either prevent/limit binding and/or slow down catalysis can be achieved by dense amorphous packing. Copyright © 2015 Elsevier Ltd. All rights reserved.

PEG-protein interaction induced contraction of NalD chains.

PubMed

Yu, Jiyan; Chen, Weizhong; Wu, Chi; Chen, Hao

2014-01-01

In a recent attempt to crystallize a regulator of MexAB-OprM multi-drug efflux systems in Pseudomonas aeruginosa (NalD), we found that adding polyethylene glycol (PEG3350, Mw = 3,350 g/mol) into the protein solution increases the speed of NalD migration in gel electrophoresis, signaling a smaller hydrodynamic size. At first we conjectured that NalD was degraded unexpectedly by PEG; however, we found that there was no change in its molar mass by MALDI-TOF characterization. Moreover, we found that adding polyacrylic acid (PAA) into the solution mixture returned the NalD migration to its normal speed. Furthermore, our analytic ultracentrifugation and dynamic laser light scattering results directly reveal that NalD interacts with PEG so that individual NalD chains gradually shrink as more PEG chains are added in the range of 10-50 mg/mL. Size exclusion chromatography also confirms that the NalD chain shrinks in the presence of PEG. A combination of these results indicates that PEG3350 chains can complex with NalD to induce an intra-protein chain contraction, presumably via the formation of hydrogen bond between -C-O-C- on PEG and -COOH on NalD, resulting in a smaller hydrodynamic size (faster migration) and a higher apparent molar mass. Note that because the presence of PEG affects osmotic pressure, it is considered to be a precipitator of protein crystallization. Our current finding reveals that the interaction of PEG/protein may play a significant role in protein crystallization. The complexation potentially makes the protein chain segments less flexible, and consequently makes crystallization easier. Hopefully, our current results will stimulate further studies in this direction.

PEG-Protein Interaction Induced Contraction of NalD Chains

PubMed Central

Yu, Jiyan; Chen, Weizhong; Wu, Chi; Chen, Hao

2014-01-01

In a recent attempt to crystallize a regulator of MexAB-OprM multi-drug efflux systems in Pseudomonas aeruginosa (NalD), we found that adding polyethylene glycol (PEG3350, Mw = 3,350 g/mol) into the protein solution increases the speed of NalD migration in gel electrophoresis, signaling a smaller hydrodynamic size. At first we conjectured that NalD was degraded unexpectedly by PEG; however, we found that there was no change in its molar mass by MALDI-TOF characterization. Moreover, we found that adding polyacrylic acid (PAA) into the solution mixture returned the NalD migration to its normal speed. Furthermore, our analytic ultracentrifugation and dynamic laser light scattering results directly reveal that NalD interacts with PEG so that individual NalD chains gradually shrink as more PEG chains are added in the range of 10–50 mg/mL. Size exclusion chromatography also confirms that the NalD chain shrinks in the presence of PEG. A combination of these results indicates that PEG3350 chains can complex with NalD to induce an intra-protein chain contraction, presumably via the formation of hydrogen bond between –C-O-C– on PEG and –COOH on NalD, resulting in a smaller hydrodynamic size (faster migration) and a higher apparent molar mass. Note that because the presence of PEG affects osmotic pressure, it is considered to be a precipitator of protein crystallization. Our current finding reveals that the interaction of PEG/protein may play a significant role in protein crystallization. The complexation potentially makes the protein chain segments less flexible, and consequently makes crystallization easier. Hopefully, our current results will stimulate further studies in this direction. PMID:24810951

Mitochondrial myopathies.

PubMed

DiMauro, Salvatore

2006-11-01

Our understanding of mitochondrial diseases (defined restrictively as defects of the mitochondrial respiratory chain) is expanding rapidly. In this review, I will give the latest information on disorders affecting predominantly or exclusively skeletal muscle. The most recently described mitochondrial myopathies are due to defects in nuclear DNA, including coenzyme Q10 deficiency and mutations in genes controlling mitochondrial DNA abundance and structure, such as POLG, TK2, and MPV17. Barth syndrome, an X-linked recessive mitochondrial myopathy/cardiopathy, is associated with decreased amount and altered structure of cardiolipin, the main phospholipid of the inner mitochondrial membrane, but a secondary impairment of respiratory chain function is plausible. The role of mutations in protein-coding genes of mitochondrial DNA in causing isolated myopathies has been confirmed. Mutations in tRNA genes of mitochondrial DNA can also cause predominantly myopathic syndromes and--contrary to conventional wisdom--these mutations can be homoplasmic. Defects in the mitochondrial respiratory chain impair energy production and almost invariably involve skeletal muscle, causing exercise intolerance, cramps, recurrent myoglobinuria, or fixed weakness, which often affects extraocular muscles and results in droopy eyelids (ptosis) and progressive external ophthalmoplegia.

Fidelity Witnesses for Fermionic Quantum Simulations

NASA Astrophysics Data System (ADS)

Gluza, M.; Kliesch, M.; Eisert, J.; Aolita, L.

2018-05-01

The experimental interest and developments in quantum spin-1 /2 chains has increased uninterruptedly over the past decade. In many instances, the target quantum simulation belongs to the broader class of noninteracting fermionic models, constituting an important benchmark. In spite of this class being analytically efficiently tractable, no direct certification tool has yet been reported for it. In fact, in experiments, certification has almost exclusively relied on notions of quantum state tomography scaling very unfavorably with the system size. Here, we develop experimentally friendly fidelity witnesses for all pure fermionic Gaussian target states. Their expectation value yields a tight lower bound to the fidelity and can be measured efficiently. We derive witnesses in full generality in the Majorana-fermion representation and apply them to experimentally relevant spin-1 /2 chains. Among others, we show how to efficiently certify strongly out-of-equilibrium dynamics in critical Ising chains. At the heart of the measurement scheme is a variant of importance sampling specially tailored to overlaps between covariance matrices. The method is shown to be robust against finite experimental-state infidelities.

Macromolecular organization of ATP synthase and complex I in whole mitochondria

PubMed Central

Davies, Karen M.; Strauss, Mike; Daum, Bertram; Kief, Jan H.; Osiewacz, Heinz D.; Rycovska, Adriana; Zickermann, Volker; Kühlbrandt, Werner

2011-01-01

We used electron cryotomography to study the molecular arrangement of large respiratory chain complexes in mitochondria from bovine heart, potato, and three types of fungi. Long rows of ATP synthase dimers were observed in intact mitochondria and cristae membrane fragments of all species that were examined. The dimer rows were found exclusively on tightly curved cristae edges. The distance between dimers along the rows varied, but within the dimer the distance between F1 heads was constant. The angle between monomers in the dimer was 70° or above. Complex I appeared as L-shaped densities in tomograms of reconstituted proteoliposomes. Similar densities were observed in flat membrane regions of mitochondrial membranes from all species except Saccharomyces cerevisiae and identified as complex I by quantum-dot labeling. The arrangement of respiratory chain proton pumps on flat cristae membranes and ATP synthase dimer rows along cristae edges was conserved in all species investigated. We propose that the supramolecular organization of respiratory chain complexes as proton sources and ATP synthase rows as proton sinks in the mitochondrial cristae ensures optimal conditions for efficient ATP synthesis. PMID:21836051

Production of starch nanoparticles using normal maize starch via heat-moisture treatment under mildly acidic conditions and homogenization.

PubMed

Park, Eun Young; Kim, Min-Jung; Cho, MyoungLae; Lee, Ju Hun; Kim, Jong-Yea

2016-10-20

Normal maize starch was subjected to heat-moisture treatment (HMT) under mildly acidic conditions (0.000, 0.050, or 0.075M H2SO4) for various treatment times (3, 5, or 8h) followed by homogenization up to 60min to prepare nanoparticles. The combination of HMT (0.075M, for 8h) and homogenization (60min) produced nanoparticles with diameters of less than 50nm at a yield higher than 80%. X-ray diffractometry and size-exclusion chromatography revealed that HMT under mildly acidic conditions selectively hydrolyzed the starch chains (especially amylose and/or long chains of amylopectin) in the amorphous region of the granules without significant damage to the crystalline structure, however, modification of the molecular structure in the amorphous region increased fragility of the granules during homogenization. Homogenization for 60min caused obvious damage in the long-range crystalline structure of the HMT starch (0.15N, for 8h), while the short-range chain associations (FT-IR) remained intact. Copyright © 2016 Elsevier Ltd. All rights reserved.

Surface-induced effects in fluctuation-based measurements of single-polymer elasticity: A direct probe of the radius of gyration

NASA Astrophysics Data System (ADS)

Innes-Gold, Sarah N.; Morgan, Ian L.; Saleh, Omar A.

2018-03-01

Single-molecule measurements of polymer elasticity are powerful, direct probes of both biomolecular structure and principles of polymer physics. Recent work has revealed low-force regimes in which biopolymer elasticity is understood through blob-based scaling models. However, the small tensions required to observe these regimes have the potential to create measurement biases, particularly due to the increased interactions of the polymer chain with tethering surfaces. Here, we examine one experimentally observed bias, in which fluctuation-based estimates of elasticity report an unexpectedly low chain compliance. We show that the effect is in good agreement with predictions based on quantifying the exclusion effect of the surface through an image-method calculation of available polymer configurations. The analysis indicates that the effect occurs at an external tension inversely proportional to the polymer's zero-tension radius of gyration. We exploit this to demonstrate a self-consistent scheme for estimating the radius of gyration of the tethered polymer. This is shown in measurements of both hyaluronic acid and poly(ethylene glycol) chains.

Statistical field theory of futures commodity prices

NASA Astrophysics Data System (ADS)

Baaquie, Belal E.; Yu, Miao

2018-02-01

The statistical theory of commodity prices has been formulated by Baaquie (2013). Further empirical studies of single (Baaquie et al., 2015) and multiple commodity prices (Baaquie et al., 2016) have provided strong evidence in support the primary assumptions of the statistical formulation. In this paper, the model for spot prices (Baaquie, 2013) is extended to model futures commodity prices using a statistical field theory of futures commodity prices. The futures prices are modeled as a two dimensional statistical field and a nonlinear Lagrangian is postulated. Empirical studies provide clear evidence in support of the model, with many nontrivial features of the model finding unexpected support from market data.

Choosing a commode for the ward environment.

PubMed

Ballinger, C; Pain, H; Pascoe, J; Gore, S

The choice of appropriate equipment to promote patient independence and enhance nursing care is of major concern to the nurse in the ward environment. This article reports on a recent evaluation of specialist commodes, (Ballinger et al, 1994), with reference to the programme funded by the Medical Devices Agency, Department of Health, under whose auspices the project was carried out. The results of user evaluations and technical tests of six mobile commodes are presented, the preferred model being the Mayfair commode supplied by Carters (J&A) Ltd. The article concludes by identifying a number of important considerations to bear in mind when selecting a commode.

7 CFR 1599.8 - Entry and handling of commodities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... approvals for entry and transit. The participant shall store and maintain the donated commodities in good...) Banners, posters or other media informing the public of the name and source of the donated commodities...

17 CFR 42.1 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false [Reserved] 42.1 Section 42.1 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION ANTI-MONEY LAUNDERING, TERRORIST FINANCING General Provisions § 42.1 [Reserved] ...