Sample records for excursion mechanical utility

  1. Improving the Science Excursion: An Educational Technologist's View

    ERIC Educational Resources Information Center

    Balson, M.

    1973-01-01

    Analyzes the nature of the learning process and attempts to show how the three components of a reinforcement contingency, the stimulus, the response and the reinforcement can be utilized to increase the efficiency of a typical science learning experience, the excursion. (JR)

  2. Knee Joint Contact Mechanics during Downhill Gait and its Relationship with Varus/Valgus Motion and Muscle Strength in Patients with Knee Osteoarthritis

    PubMed Central

    Farrokhi, Shawn; Voycheck, Carrie A.; Gustafson, Jonathan A.; Fitzgerald, G. Kelley; Tashman, Scott

    2015-01-01

    Objective The objective of this exploratory study was to evaluate tibiofemoral joint contact point excursions and velocities during downhill gait and assess the relationship between tibiofemoral joint contact mechanics with frontal-plane knee joint motion and lower extremity muscle weakness in patients with knee osteoarthritis (OA). Methods Dynamic stereo X-ray was used to quantify tibiofemoral joint contact mechanics and frontal-plane motion during the loading response phase of downhill gait in 11 patients with knee OA and 11 control volunteers. Quantitative testing of the quadriceps and the hip abductor muscles was also performed. Group differences in contact mechanics and frontal-plane motion excursions were compared using analysis of covariance with adjustments for body mass index. Differences in strength were compared using independent sample t-tests. Additionally, linear associations between contact mechanics with frontal-plane knee motion and muscle strength were evaluated using Pearson's correlation coefficients. Results Patients with knee OA demonstrated larger medial/lateral joint contact point excursions (p<0.02) and greater heel-strike joint contact point velocities (p<0.05) for the medial and lateral compartments compared to the control group. The peak medial/lateral joint contact point velocity of the medial compartment was also greater for patients with knee OA compared to their control counterparts (p=0.02). Additionally, patients with knee OA demonstrated significantly increased frontal-plane varus motion excursions (p<0.01) and greater quadriceps and hip abductor muscle weakness (p=0.03). In general, increased joint contact point excursions and velocities in patients with knee OA were linearly associated with greater frontal-plane varus motion excursions (p<0.04) but not with quadriceps or hip abductor strength. Conclusion Altered contact mechanics in patients with knee OA may be related to compromised frontal-plane joint stability but not with deficits in muscle strength. PMID:27030846

  3. Compensation for large thorax excursions in EIT imaging.

    PubMed

    Schullcke, B; Krueger-Ziolek, S; Gong, B; Mueller-Lisse, U; Moeller, K

    2016-09-01

    Besides the application of EIT in the intensive care unit it has recently also been used in spontaneously breathing patients suffering from asthma bronchiole, cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). In these cases large thorax excursions during deep inspiration, e.g. during lung function testing, lead to artifacts in the reconstructed images. In this paper we introduce a new approach to compensate for image artifacts resulting from excursion induced changes in boundary voltages. It is shown in a simulation study that boundary voltage change due to thorax excursion on a homogeneous model can be used to modify the measured voltages and thus reduce the impact of thorax excursion on the reconstructed images. The applicability of the method on human subjects is demonstrated utilizing a motion-tracking-system. The proposed technique leads to fewer artifacts in the reconstructed images and improves image quality without substantial increase in computational effort, making the approach suitable for real-time imaging of lung ventilation. This might help to establish EIT as a supplemental tool for lung function tests in spontaneously breathing patients to support clinicians in diagnosis and monitoring of disease progression.

  4. Knee joint contact mechanics during downhill gait and its relationship with varus/valgus motion and muscle strength in patients with knee osteoarthritis.

    PubMed

    Farrokhi, Shawn; Voycheck, Carrie A; Gustafson, Jonathan A; Fitzgerald, G Kelley; Tashman, Scott

    2016-01-01

    The objective of this exploratory study was to evaluate tibiofemoral joint contact point excursions and velocities during downhill gait and assess the relationship between tibiofemoral joint contact mechanics with frontal-plane knee joint motion and lower extremity muscle weakness in patients with knee osteoarthritis (OA). Dynamic stereo X-ray was used to quantify tibiofemoral joint contact mechanics and frontal-plane motion during the loading response phase of downhill gait in 11 patients with knee OA and 11 control volunteers. Quantitative testing of the quadriceps and the hip abductor muscles was also performed. Patients with knee OA demonstrated larger medial/lateral joint contact point excursions (p < 0.02) and greater heel-strike joint contact point velocities (p < 0.05) for the medial and lateral compartments compared to the control group. The peak medial/lateral joint contact point velocity of the medial compartment was also greater for patients with knee OA compared to their control counterparts (p = 0.02). Additionally, patients with knee OA demonstrated significantly increased frontal-plane varus motion excursions (p < 0.01) and greater quadriceps and hip abductor muscle weakness (p = 0.03). In general, increased joint contact point excursions and velocities in patients with knee OA were linearly associated with greater frontal-plane varus motion excursions (p < 0.04) but not with quadriceps or hip abductor strength. Altered contact mechanics in patients with knee OA may be related to compromised frontal-plane joint stability but not with deficits in muscle strength.

  5. Dynamic Balance Deficits 6 Months Following First-Time Acute Lateral Ankle Sprain: A Laboratory Analysis.

    PubMed

    Doherty, Cailbhe; Bleakley, Chris; Hertel, Jay; Caulfield, Brian; Ryan, John; Delahunt, Eamonn

    2015-08-01

    Controlled laboratory study. To utilize kinematic and stabilometric measures to compare dynamic balance during performance of the Star Excursion Balance Test between persons 6 months following first-time lateral ankle sprain (LAS) and a noninjured control group. Biomechanical evaluation of dynamic balance in persons following first-time LAS during performance of the Star Excursion Balance Test could provide insight into the mechanisms by which individuals proceed to recover fully or develop chronic ankle instability. Sagittal plane kinematics of the lower extremity and the center-of-pressure path during the performance of the anterior, posterolateral, and posteromedial reach directions of the Star Excursion Balance Test were obtained from 69 participants 6 months following first-time acute LAS and from a control group of 20 noninjured participants. Compared to the control group, the LAS group displayed lower normalized reach distances in all 3 reach directions on the injured and noninjured limbs, with the largest observed effect size in the posterolateral direction (P = .001, ηp(2) = 0.07). The performance impairment was associated with less hip and knee flexion and ankle dorsiflexion at the point of maximum reach (P<.02), and coincided with less complexity of the center-of-pressure path (P<.05). Participants with a 6-month history of LAS exhibit a persistence of deficits previously established in the acute phase of injury.

  6. Intermittent, noncyclic dysfunction of a mechanical aortic prosthesis by pannus formation.

    PubMed

    Giroux, Sylvie K; Labinaz, Marino X; Grisoli, Dominique; Klug, Andrew P; Veinot, John P; Burwash, Ian G

    2010-01-01

    Mechanical aortic prosthesis dysfunction can result from thrombosis or pannus formation. Pannus formation usually restricts systolic excursion of the occluding disk, resulting in progressive stenosis of the aortic prosthesis. Intermittent dysfunction of a mechanical aortic prosthesis is usually ascribed to thrombus formation. We describe an unusual case of intermittent, noncyclic dysfunction of a mechanical aortic prosthesis due to pannus formation in the absence of systolic restriction of disk excursion that presented with intermittent massive aortic regurgitation, severe ischemia, and shock. Pannus formation should be considered as a potential cause of acute intermittent severe aortic regurgitation in a patient with a mechanical aortic prosthesis.

  7. Rapid directional changes associated with a 6.5 kyr-long Blake geomagnetic excursion at the Blake-Bahama Outer Ridge

    NASA Astrophysics Data System (ADS)

    Bourne, Mark; Mac Niocaill, Conall; Thomas, Alex L.; Knudsen, Mads Faurschou; Henderson, Gideon M.

    2012-06-01

    Geomagnetic excursions are recognized as intrinsic features of the Earth's magnetic field. High-resolution records of field behaviour, captured in marine sedimentary cores, present an opportunity to determine the temporal and geometric character of the field during geomagnetic excursions and provide constraints on the mechanisms producing field variability. We present here the highest resolution record yet published of the Blake geomagnetic excursion (∼125 ka) measured in three cores from Ocean Drilling Program (ODP) Site 1062 on the Blake-Bahama Outer Ridge. The Blake excursion has a controversial structure and timing but these cores have a sufficiently high sedimentation rate (∼10 cm ka-1) to allow detailed reconstruction of the field behaviour at this site during the excursion. Palaeomagnetic measurements of the cores reveal rapid transitions (<500 yr) between the contemporary stable normal polarity and a completely reversed state of long duration which spans a stratigraphic interval of 0.7 m. We determine the duration of the reversed state during the Blake excursion using oxygen isotope stratigraphy, combined with 230Th excess measurements to assess variations in the sedimentation rates through the sections of interest. This provides an age and duration for the Blake excursion with greater accuracy and with constrained uncertainty. We date the directional excursion as falling between 129 and 122 ka with a duration for the deviation of 6.5±1.3 kyr. The long duration of this interval and the fully reversed field suggest the existence of a pseudo-stable, reversed dipole field component during the excursion and challenge the idea that excursions are always of short duration.

  8. Head Excursion of Restrained Human Volunteers and Hybrid III Dummies in Steady State Rollover Tests

    PubMed Central

    Moffatt, Edward; Hare, Barry; Hughes, Raymond; Lewis, Lance; Iiyama, Hiroshi; Curzon, Anne; Cooper, Eddie

    2003-01-01

    Seatbelts provide substantial benefits in rollover crashes, yet occupants still receive head and neck injuries from contacting the vehicle roof interior when the roof exterior strikes the ground. Prior research has evaluated rollover restraint performance utilizing anthropomorphic test devices (dummies), but little dynamic testing has been done with human volunteers to learn how they move during rollovers. In this study, the vertical excursion of the head of restrained dummies and human subjects was measured in a vehicle being rotated about its longitudinal roll axis at roll rates from 180-to-360 deg/sec and under static inversion conditions. The vehicle’s restraint design was the commonly used 3-point seatbelt with continuous loop webbing and a sliding latch plate. This paper presents an analysis of the observed occupant motion and provides a comparison of dummy and human motion under similar test conditions. Thirty-five tests (eighteen static and seventeen dynamic) were completed using two different sizes of dummies and human subjects in both near and far-side roll directions. The research indicates that far-side rollovers cause the restrained test subjects to have greater head excursion than near-side rollovers, and that static inversion testing underestimates head excursion for far-side occupants. Human vertical head excursion of up to 200 mm was found at a roll rate of 220 deg/sec. Humans exhibit greater variability in head excursion in comparison to dummies. Transfer of seatbelt webbing through the latch plate did not correlate directly with differences in head excursion. PMID:12941241

  9. Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

    PubMed

    Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

    2017-07-01

    Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (-) r(14) = -0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight on the relationship between relative fascicle excursions and joint function.

  10. Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children

    PubMed Central

    Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

    2017-01-01

    Abstract Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles’ force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (–) r(14) = −0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight on the relationship between relative fascicle excursions and joint function. PMID:28723790

  11. Midtarsal locking, the windlass mechanism, and running strike pattern: A kinematic and kinetic assessment.

    PubMed

    Bruening, Dustin A; Pohl, Michael B; Takahashi, Kota Z; Barrios, Joaquin A

    2018-05-17

    Changes in running strike pattern affect ankle and knee mechanics, but little is known about the influence of strike pattern on the joints distal to the ankle. The purpose of this study was to explore the effects of forefoot strike (FFS) and rearfoot strike (RFS) running patterns on foot kinematics and kinetics, from the perspectives of the midtarsal locking theory and the windlass mechanism. Per the midtarsal locking theory, we hypothesized that the ankle would be more inverted in early stance when using a FFS, resulting in decreased midtarsal joint excursions and increased dynamic stiffness. Associated with a more engaged windlass mechanism, we hypothesized that a FFS would elicit increased metatarsophalangeal joint excursions and negative work in late stance. Eighteen healthy female runners ran overground with both FFS and RFS patterns. Instrumented motion capture and a validated multi-segment foot model were used to analyze midtarsal and metatarsophalangeal joint kinematics and kinetics. During early stance in FFS the ankle was more inverted, with concurrently decreased midtarsal eversion (p < 0.001) and abduction excursions (p = 0.003) but increased dorsiflexion excursion (p = 0.005). Dynamic midtarsal stiffness did not differ (p = 0.761). During late stance in FFS, metatarsophalangeal extension was increased (p = 0.009), with concurrently increased negative work (p < 0.001). In addition, there was simultaneously increased midtarsal positive work (p < 0.001), suggesting enhanced power transfer in FFS. Clear evidence for the presence of midtarsal locking was not observed in either strike pattern during running. However, the windlass mechanism appeared to be engaged to a greater extent during FFS. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Short-term mechanisms of toxic action of airborne particulates underlie dose-rate dependent health risks and support control of one-hour airborne particle levels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Michaels, R.A.; Kleinman, M.T.

    1999-07-01

    Twenty-four-hour airborne particle mass levels permissible under the NAAQS have been associated with mortality and morbidity in communities, motivating reconsideration of the standard. Reports of shorter-term mechanisms of toxic action exerted by airborne PM and PM constituents are emerging. The mechanisms are diverse, but have in common a short time frame of toxic action, from minutes to hours. In view of documented PM excursions also lasting minutes to hours, this study inquires whether such short-term mechanisms might contribute to explaining daily morbidity and mortality. Toxicology experiments have demonstrated the harmfulness of brief exposure to PM levels in the range ofmore » observed excursions. This suggests that toxicological processes initiated by short-term inhalation of PM may exert clinically important effects, and that weak associations of 24-hour-average particle mass with mortality and morbidity may represent artifacts of stronger, shorter-term associations whose full magnitude remains to be quantified. In one study, the area of lung surface developing lesions was elevated in rats breathing the same four-hour dose of aerosols, when the four-hour average rate of aerosol delivery included a short-term (five-minute) burst fifty percent above the average dose rate. Elevations were observed with each of two aerosols tested. The magnitude of the effect was higher with one of the two aerosols, whose dose rate included four excursions rather than just one excursion. Particulate matter inhaled or instilled intratracheally has produced morbidity in animals, including apnea and electrophysiological effects in dogs. Other studies reveal that PM can kill rats via electrophysiological and possibly other mechanisms. PM has also adversely affected asthmatic people in controlled clinical settings during exercise or, in one study, at rest.« less

  13. Turbulence flight director analysis and preliminary simulation

    NASA Technical Reports Server (NTRS)

    Johnson, D. E.; Klein, R. E.

    1974-01-01

    A control column and trottle flight director display system is synthesized for use during flight through severe turbulence. The column system is designed to minimize airspeed excursions without overdriving attitude. The throttle system is designed to augment the airspeed regulation and provide an indication of the trim thrust required for any desired flight path angle. Together they form an energy management system to provide harmonious display indications of current aircraft motions and required corrective action, minimize gust upset tendencies, minimize unsafe aircraft excursions, and maintain satisfactory ride qualities. A preliminary fixed-base piloted simulation verified the analysis and provided a shakedown for a more sophisticated moving-base simulation to be accomplished next. This preliminary simulation utilized a flight scenario concept combining piloting tasks, random turbulence, and discrete gusts to create a high but realistic pilot workload conducive to pilot error and potential upset. The turbulence director (energy management) system significantly reduced pilot workload and minimized unsafe aircraft excursions.

  14. Temperature-Controlled Clamping and Releasing Mechanism

    NASA Technical Reports Server (NTRS)

    Rosing, David; Ford, Virginia

    2005-01-01

    A report describes the development of a mechanism that automatically clamps upon warming and releases upon cooling between temperature limits of approx. =180 K and approx. =293 K. The mechanism satisfied a need specific to a program that involved repeated excursions of a spectrometer between a room-temperature atmospheric environment and a cryogenic vacuum testing environment. The mechanism was also to be utilized in the intended application of the spectrometer, in which the spectrometer would be clamped for protection during launch of a spacecraft and released in the cold of outer space to allow it to assume its nominal configuration for scientific observations. The mechanism is passive in the sense that its operation does not depend on a control system and does not require any power other than that incidental to heating and cooling. The clamping and releasing action is effected by bolt-preloaded stacks of shape-memory-alloy (SMA) cylinders. In designing this mechanism, as in designing other, similar SMA mechanisms, it was necessary to account for the complex interplay among thermal expansion, elastic and inelastic deformation under load, and SMA thermomechanical properties.

  15. Control of large thermal distortions in a cryogenic wind tunnel

    NASA Technical Reports Server (NTRS)

    Gustafson, J. C.

    1983-01-01

    The National Transonic Facility (NTF) is a research wind tunnel capable of operation at temperatures down to 89K (160 R) and pressures up to 900,000 Pa (9 atmospheres) to achieve Reynolds numbers approaching 120,000,000. Wide temperature excursions combined with the precise alignment requirements of the tunnel aerodynamic surfaces imposed constraints on the mechanisms supporting the internal structures of the tunnel. The material selections suitable for this application were also limited. A general design philosophy of utilizing a single fixed point for each linear degree of freedom and guiding the expansion as required was adopted. These support systems allow thermal expansion to take place in a manner that minimizes the development of thermally induced stresses while maintaining structural alignment and resisting high aerodynamic loads. Typical of the support mechanisms are the preload brackets used in the fan shroud system and the Watts linkage used to support the upstream nacelle. The design of these mechanisms along with the basic design requirements and the constraints imposed by the tunnel system are discussed.

  16. Exploring the Angstrom Excursion of Au Nanoparticles Excited away from a Metal Surface by an Impulsive Acoustic Perturbation.

    PubMed

    Kim, Ji-Wan; Kovalenko, Oleksandr; Liu, Yu; Bigot, Jean-Yves

    2016-12-27

    We report the anharmonic angstrom dynamics of self-assembled Au nanoparticles (Au:NPs) away from a nickel surface on top of which they are coupled by their near-field interaction. The deformation and the oscillatory excursion away from the surface are induced by picosecond acoustic pulses and probed at the surface plasmon resonance with femtosecond laser pulses. The overall dynamics are due to an efficient transfer of translational momentum from the Ni surface to the Au:NPs, therefore avoiding usual thermal effects and energy redistribution among the electronic states. Two modes are clearly revealed by the oscillatory shift of the Au:NPs surface plasmon resonance-the quadrupole deformation mode due to the transient ellipsoid shape and the excursion mode when the Au:NPs bounce away from the surface. We find that, contrary to the quadrupole mode, the excursion mode is sensitive to the distance between Au:NPs and Ni. Importantly, the excursion dynamics display a nonsinusoidal motion that cannot be explained by a standard harmonic potential model. A detailed modeling of the dynamics using a Hamaker-type Lennard-Jones potential between two media is performed, showing that each Au:NPs coherently evolves in a nearly one-dimensional anharmonic potential with a total excursion of ∼1 Å. This excursion induces a shift of the surface plasmon resonance detectable because of the strong near-field interaction. This general method of observing the spatiotemporal dynamics with angstrom and picosecond resolutions can be directly transposed to many nanostructures or biosystems to reveal the interaction and contact mechanism with their surrounding medium while remaining in their fundamental electronic states.

  17. Four-dimensional analysis by high-speed holographic imaging reveals a chiral memory of sperm flagella.

    PubMed

    Muschol, Michael; Wenders, Caroline; Wennemuth, Gunther

    2018-01-01

    Here high-speed Digital Holographic Microscopy (DHM) records sperm flagellar waveforms and swimming paths in 4 dimensions (X, Z, and t). We find flagellar excursions into the Z-plane nearly as large as the envelope of the flagellar waveform projected onto the XY-plane. These Z-plane excursions travel as waves down the flagellum each beat cycle. DHM also tracks the heads of free-swimming sperm and the dynamics and chirality of rolling of sperm around their long axis. We find that mouse sperm roll CW at the maximum positive Z-plane excursion of the head, then roll CCW at the subsequent maximum negative Z-plane excursion. This alternating chirality of rolling indicates sperm have a chiral memory. Procrustes alignments of path trajectories for sequences of roll-counterroll cycles show that path chirality is always CW for the cells analyzed in this study. Human and bull sperm lack distinguishable left and right surfaces, but DHM still indicates coordination of Z-plane excursions and rolling events. We propose that sperm have a chiral memory that resides in a hypothetical elastic linkage within the flagellar machinery, which stores some of the torque required for a CW or CCW roll to reuse in the following counter-roll. Separate mechanisms control path chirality.

  18. Intermittent, Non Cyclic Severe Mechanical Aortic Valve Regurgitation

    PubMed Central

    Choi, Jong Hyun; Song, Seunghwan; Lee, Myung-Yong

    2013-01-01

    Mechanical aortic prosthesis dysfunction can result from thrombosis or pannus formation. We describe an unusual case of intermittent, non cyclic mechanical aortic prosthesis dysfunction due to pannus formation with thrombus in the absence of systolic restriction of disk excursion, that presented with intermittent severe aortic regurgitation. PMID:24459568

  19. Entry Trajectory Issues for the Stardust Sample Return Capsule

    NASA Technical Reports Server (NTRS)

    Desai, Prasun N.; Mitcheltree, Robert A.; Cheatwood, F. McNeil

    1999-01-01

    The Stardust mission was successfully launched on February 7, 1999. It will be the first mission to return samples from a comet. The sample return capsule, which is passively controlled during the fastest Earth entry ever, will land by parachute in Utah. The present study describes the analysis of the entry, descent, and landing of the returning sample capsule utilizing the final, launch configuration capsule mass properties. The effects of two aerodynamic instabilities are revealed (one in the high altitude free molecular regime and the other in the transonic/subsonic flow regime). These instabilities could lead to unacceptably large excursions in the angle-of-attack near peak heating and main parachute deployment, respectively. To reduce the excursions resulting from the high altitude instability, the entry spin rate of the capsule is increased. To stabilize the excursions from the transonic/subsonic instability, a drogue chute with deployment triggered by a gravity-switch and timer is added prior to main parachute deployment. A Monte Carlo dispersion analysis of the modified entry (from which the impact of off-nominal conditions during the entry is ascertained) predicts that the capsule attitude excursions near peak heating and drogue chute deployment are within Stardust mission limits. Additionally, the size of the resulting 3-sigma landing ellipse is 60.8 km in downrange by 19.9 km in crossrange, which is within the Utah Test and Training Range boundaries.

  20. Burn Control Mechanisms in Tokamaks

    NASA Astrophysics Data System (ADS)

    Hill, M. A.; Stacey, W. M.

    2015-11-01

    Burn control and passive safety in accident scenarios will be an important design consideration in future tokamak reactors, in particular fusion-fission hybrid reactors, e.g. the Subcritical Advanced Burner Reactor. We are developing a burning plasma dynamics code to explore various aspects of burn control, with the intent to identify feedback mechanisms that would prevent power excursions. This code solves the coupled set of global density and temperature equations, using scaling relations from experimental fits. Predictions of densities and temperatures have been benchmarked against DIII-D data. We are examining several potential feedback mechanisms to limit power excursions: i) ion-orbit loss, ii) thermal instability density limits, iii) MHD instability limits, iv) the degradation of alpha-particle confinement, v) modifications to the radial current profile, vi) ``divertor choking'' and vii) Type 1 ELMs. Work supported by the US DOE under DE-FG02-00ER54538, DE-FC02-04ER54698.

  1. Sex-specific gait adaptations prior to and up to six months after ACL reconstruction

    PubMed Central

    Stasi, Stephanie L. Di; Hartigan, Erin H.; Snyder-Mackler, Lynn

    2015-01-01

    STUDY DESIGN Controlled longitudinal laboratory study. OBJECTIVES Compare sagittal plane gait mechanics of men and women before and up to 6 months after anterior cruciate ligament reconstruction (ACLR). BACKGROUND Aberrant gait patterns are ubiquitous after anterior cruciate ligament (ACL) rupture and persist after ACLR despite skilled physical therapy. Sex influences post-operative function and second ACL injury risk, but its influence on gait adaptations after injury have not been investigated. METHODS Sagittal plane knee and hip joint excursions during midstance and internal knee and hip extension moments at peak knee flexion were collected on 12 women and 27 men using 3-dimensional gait analysis before (Screen) and after pre-operative physical therapy (Pre-sx), and 6 months after ACLR (6mo). Repeated measures analysis of variance models were used to determine whether limb asymmetries changed differently over time in men and women. RESULTS Significant time x limb x sex interactions were identified for hip and knee excursions and internal knee extension moments (P≤.007). Both sexes demonstrated smaller knee excursions on the involved compared to the uninvolved knee at each time point (P≤.007), but only women demonstrated a decrease in the involved knee excursion from pre-sx to 6mo (P=.03). Women also demonstrated smaller hip excursions (P<.001) and internal knee extension moments (P=.005) on the involved limb compared to the uninvolved limb at 6mo. Men demonstrated smaller hip excursions and knee moments on the involved limb compared to the uninvolved limb (main effects, P<.001). CONCLUSION The persistence of limb asymmetries in men and women 6 months after ACLR indicates that current rehabilitation efforts are inadequate for some individuals following ACLR. PMID:25627155

  2. Geomagnetic excursions in the Brunhes and Matuyama Chrons: Do they come in bunches?

    NASA Astrophysics Data System (ADS)

    Channell, J. E. T.

    2012-04-01

    Geomagnetic excursions, defined here as brief directional aberrations of the main dipole field outside the range of expected secular variation, remain controversial. Poorly-correlated records of apparent excursions from lavas and sediments can often be assigned to sampling artifacts, sedimentological phenomena, volcanic terrane effects, or local secular variation, rather than behavior of the main dipole field. Although records of magnetic excursions date from the 1960s, the number of Brunhes excursions in recent reviews of the subject have reached the 12-17 range, of which only about ~7 are adequately and/or consistently recorded. For the Matuyama Chron, the current inventory of excursions stands at about 10. The better quality excursion records, with reasonable age control, imply millennial-scale or even sub-millennial-scale durations. When "adequately" recorded, excursions are manifest as paired polarity reversals flanking virtual geomagnetic poles (VGPs) that reach high latitudes in the opposite hemisphere. At the young end of the excursion record, the Mono Lake (~33 ka) and Laschamp (~41 ka) excursions are well documented, although records of the former are not widely distributed. Several excursions younger than the Mono Lake excursion (at 17 ka and 25 ka) have recently been recorded in lavas and sediments, respectively. Is the 17-41 ka interval characterized by multiple excursions? Similarly, multiple excursions have been recorded in the 188-238 ka interval that encompasses records of the Iceland Basin excursion (~188 ka) and the Pringle Falls (PF) excursion. The PF excursion has been assigned ages in the 211-238 ka range. Does this mean that this interval is also characterized by several discrete excursions? The 500-600 ka interval incorporates not only the Big Lost excursion at ~565 ka, but also anomalous magnetization directions from lava flows, particularly in the West Eifel volcanics that yield mid-latitude northern-hemisphere VGPs with a range of Ar/Ar ages. The key question is whether such intervals of mid-latitude VGPs denote high-amplitude secular variation or inadequately recorded magnetic excursions. We propose that excursions characterized by high VGP latitudes in the opposite hemisphere should be termed Category 1 excursions, and those manifest by low/mid-latitude VGPs should be termed Category 2 excursions. In the future, improved records may "elevate" Category 2 excursions to Category 1. We do not view this subdivision of Category 1 and Category 2 excursions as necessarily a geomagnetic distinction, but possibly a distinction based on recording fidelity.

  3. Excursion Processes Associated with Elliptic Combinatorics

    NASA Astrophysics Data System (ADS)

    Baba, Hiroya; Katori, Makoto

    2018-06-01

    Researching elliptic analogues for equalities and formulas is a new trend in enumerative combinatorics which has followed the previous trend of studying q-analogues. Recently Schlosser proposed a lattice path model in the square lattice with a family of totally elliptic weight-functions including several complex parameters and discussed an elliptic extension of the binomial theorem. In the present paper, we introduce a family of discrete-time excursion processes on Z starting from the origin and returning to the origin in a given time duration 2 T associated with Schlosser's elliptic combinatorics. The processes are inhomogeneous both in space and time and hence expected to provide new models in non-equilibrium statistical mechanics. By numerical calculation we show that the maximum likelihood trajectories on the spatio-temporal plane of the elliptic excursion processes and of their reduced trigonometric versions are not straight lines in general but are nontrivially curved depending on parameters. We analyze asymptotic probability laws in the long-term limit T → ∞ for a simplified trigonometric version of excursion process. Emergence of nontrivial curves of trajectories in a large scale of space and time from the elementary elliptic weight-functions exhibits a new aspect of elliptic combinatorics.

  4. Excursion Processes Associated with Elliptic Combinatorics

    NASA Astrophysics Data System (ADS)

    Baba, Hiroya; Katori, Makoto

    2018-04-01

    Researching elliptic analogues for equalities and formulas is a new trend in enumerative combinatorics which has followed the previous trend of studying q-analogues. Recently Schlosser proposed a lattice path model in the square lattice with a family of totally elliptic weight-functions including several complex parameters and discussed an elliptic extension of the binomial theorem. In the present paper, we introduce a family of discrete-time excursion processes on Z starting from the origin and returning to the origin in a given time duration 2T associated with Schlosser's elliptic combinatorics. The processes are inhomogeneous both in space and time and hence expected to provide new models in non-equilibrium statistical mechanics. By numerical calculation we show that the maximum likelihood trajectories on the spatio-temporal plane of the elliptic excursion processes and of their reduced trigonometric versions are not straight lines in general but are nontrivially curved depending on parameters. We analyze asymptotic probability laws in the long-term limit T → ∞ for a simplified trigonometric version of excursion process. Emergence of nontrivial curves of trajectories in a large scale of space and time from the elementary elliptic weight-functions exhibits a new aspect of elliptic combinatorics.

  5. Quaternary magnetic excursions recorded in marine sediments.

    NASA Astrophysics Data System (ADS)

    Channell, J. E. T.

    2017-12-01

    This year is the golden (50th) anniversary of the first documentation of a magnetic excursion, the Laschamp excursion in volcanics from the Chaine des Puys (Bonhommet and Babkine, 1967). The first recording of an excursion in sediments was from the Blake Outer Ridge (Smith and Foster, 1969). Magnetic excursions are directional aberrations of the geomagnetic field apparently involving short-lived reversal of the main dipole field. They have durations of a few kyrs, and are therefore rarely recorded in sediments with mean sedimentation rates <10 cm/kyr. Certain Brunhes-aged excursions are now well documented having been recorded in both marine sediments and in lavas (Laschamp excursion, 41 ka). Other excursions have not been adequately recorded in lavas, but have been widely recorded in marine and lake sediments (Iceland Basin excursion, 190 ka). The recording of excursions is fortuitous both in lava sequences and in marine sediments due to their millennial/centennial-scale duration, however, the global recording of the Laschamp and Iceland Basin excursions imply that excursions involve the main dipole field, are recorded synchronously over the globe, and are therefore important in stratigraphic correlation. The marine sediment record includes magnetic excursions at 26 ka (Rockall), 32 ka (Mono Lake), 41 ka (Laschamp), 115 ka (Blake), 190 ka (Iceland Basin), 238 ka (Pringle Falls?), 286 ka (Portuguese Orphan), 495 ka (Bermuda), 540 ka (Big Lost), 590 ka (La Palma), and 670 ka (Osaka Bay), implying at least 11 excursions in the Brunhes Chron. For the Matuyama Chron, excursions have been recorded in marine sediments at 868 ka (Kamikatsura?), 932 ka (Santa Rosa), 1051 ka (Intra-Jaramillo), 1115 ka (Punaruu), 1255 ka (Bjorn), 1476 ka (Gardar), 1580 ka (Gilsa), and 2737 ka (Porcupine). Excursions coincide with minima in relative paleointensity (RPI) records. Ages are from correlation of excursion records to oxygen isotope records in the same cores, and ice-volume calibration of the oxygen isotope template. The marine sediment record of excursions, combined with independent documentation of excursions in lavas with Ar/Ar age control, is progressively strengthening our knowledge of the excursion inventory in the Quaternary, and enhancing the importance of excursions and RPI in Quaternary stratigraphy.

  6. Depriming of arterial heat pipes: An investigation of CTS thermal excursions

    NASA Technical Reports Server (NTRS)

    Antoniuk, D.; Edwards, D. K.

    1980-01-01

    Four thermal excursions of the Transmitter Experiment Package (TEP) were the result of the depriming of the arteries in all three heat pipes in the Variable Conductance Heat Pipe System which cooled the TEP. The determined cause of the depriming of the heat pipes was the formation of bubbles of the nitrogen/helium control gas mixture in the arteries during the thaw portion of a freeze/thaw cycle of the inactive region of the condenser section of the heat pipe. Conditions such as suction freezeout or heat pipe turn-on, which moved these bubbles into the active region of the heat pipe, contributed to the depriming mechanism. Methods for precluding, or reducing the probability of, this type of failure mechanism in future applications of arterial heat pipes are included.

  7. Comment [on 'Are Proterozoic cap carbonates and isotopic excursions a record of gas hydrate destabilization following Earth’s coldest intervals?, Kennedy et al., Geology 29(5), 442-446

    USGS Publications Warehouse

    Max, M.D.; Dillon, William P.

    2002-01-01

    We welcome the evidence noted by Kennedy et al. (2001) for strong methane excursions associated with the cessation of glacial episodes. They identify the carbon in cap carbonates overlying glacial sediments as probably being of biogenic origin and as likely having had a biogenic methane source. These authors suggest that the methane was released from gas hydrate, which we agree is likely. However, we suggest a different mechanism for that release, rather than their suggested warming event. We propose that a dominantly pressure-related mechanism would be more plausible for releasing sufficient methane from the huge gas hydrate reservoir to modify the global greenhouse and drive global warming in a geological instant.

  8. Variability in mid-depth ventilation of the western Atlantic Ocean during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Voigt, I.; Cruz, A. P. S.; Mulitza, S.; Chiessi, C. M.; Mackensen, A.; Lippold, J.; Antz, B.; Zabel, M.; Zhang, Y.; Barbosa, C. F.; Tisserand, A. A.

    2017-09-01

    Negative stable carbon isotopic excursions have been observed throughout most of the mid-depth ( 1000-3000 m) Atlantic Ocean during Heinrich Stadial 1 (HS1) and the Younger Dryas (YD). Although there is an agreement that these mid-depth excursions were in some way associated with a slowdown of the Atlantic Meridional Overturning Circulation (AMOC), there is still no consensus on the precise mechanism(s). Here we present benthic stable carbon and oxygen isotopic (δ13C and δ18O) records from five cores from the western equatorial Atlantic (WEA). Together with published benthic isotopic records from nearby cores, we produced a WEA depth transect ( 800-2500 m). We compare HS1 and YD data from this transect with data from previously published North and South Atlantic cores and demonstrate that the largest negative δ13C excursions occurred in the WEA during these times. Moreover, our benthic δ18O records require the presence of two water masses flowing from the Southern Ocean, bisected by a Northern Component Water (NCW). Given that δ18O is a conservative water mass tracer, we suggest that δ13C was decoupled from water mass composition and does not correspond to simple alternations between northern and southern sourced waters. Instead, δ13C behaved non-conservatively during HS1 and the YD. Consistently with our new 231Pa/230Th record from the WEA transect, that allowed the reconstruction of AMOC strength, we hypothesize that the negative δ13C excursions reflect an increase in the residence time of NCW in response to a weakened AMOC, allowing for a marked accumulation of 13C-depleted respired carbon at the mid-depth WEA.

  9. High-resolution record of the Laschamp geomagnetic excursion at the Blake-Bahama Outer Ridge

    NASA Astrophysics Data System (ADS)

    Bourne, Mark D.; Mac Niocaill, Conall; Thomas, Alex L.; Henderson, Gideon M.

    2013-12-01

    Geomagnetic excursions are brief deviations of the geomagnetic field from behaviour expected during `normal secular' variation. The Laschamp excursion at ˜41 ka was one such deviation. Previously published records suggest rapid changes in field direction and a concurrent substantial decrease in field intensity associated with this excursion. Accurate dating of excursions, and determination of their durations from multiple locations, is vital to our understanding of global field behaviour during these deviations. We present here high-resolution palaeomagnetic records of the Laschamp excursion obtained from two Ocean Drilling Program (ODP) Sites, 1061 and 1062 on the Blake-Bahama Outer Ridge (ODP Leg 172). High sedimentation rates (˜30-40 cm kyr-1) at these locations allow determination of transitional field behaviour during the excursion. Palaeomagnetic measurements of discrete samples from four cores reveal a single excursional feature, across an interval of 30 cm, associated with a broader palaeointensity low. We determine the age and duration of the Laschamp excursion using a stratigraphy linked to the δ18O record from the Greenland ice cores. This chronology dates the Laschamp excursion at the Blake Ridge to 41.3 ka. The excursion is characterized by rapid transitions (less than 200 yr) between stable normal polarity and a partially reversed polarity state. The palaeointensity record is in good agreement between the two sites, revealing two prominent minima. The first minimum is associated with the Laschamp excursion at 41 ka and the second corresponds to the Mono Lake excursion at ˜35.5 ka. We determine that the directional excursion during the Laschamp at this location was no longer than ˜400 yr, occurring within a palaeointensity minimum that lasted 2000 yr. The Laschamp excursion at this location is much shorter in duration than the Blake and Iceland Basin excursions.

  10. A reassessment of the role of tidal dispersion in estuaries and bays

    USGS Publications Warehouse

    Geyer, W. Rockwell; Signell, Richard P.

    1992-01-01

    The role of tidal dispersion is reassessed, based on a consideration of the relevant physical mechanisms, particularly those elucidated by numerical simulations of tide-induced dispersion. It appears that the principal influence of tidal currents on dispersion occurs at length scales of the tidal excursion and smaller; thus the effectiveness of tidal dispersion depends on the relative scale of the tidal excursion to the spacing between major bathymetric and shoreline features. In estuaries where the typical spacing of topographic features is less than the tidal excursion, tidal dispersion may contribute significantly to the overall flushing. In estuaries and embayments in which the typical spacing between major features is larger than the tidal excursion, the influence of tidal dispersion will be localized, and it will not markedly contribute to overall flushing. Tidal dispersion is most pronounced in regions of abrupt topographic changes such as headlands and inlets, where flow separation occurs. The strong strain rate in the region of flow separation tends to stretch patches of fluid into long filaments, which are subsequently rolled up and distorted by the transient eddy field. The dispersion process accomplished by the tides varies strongly as a function of position and tidal phase and thus does not lend itself to parameterization by an eddy diffusion coefficient.

  11. Harry Truman and the Atomic Bomb: An Excursion into Character Education through Storytelling

    ERIC Educational Resources Information Center

    Sanchez, Tony R.

    2006-01-01

    This article asserts the importance of character education through the utilization of historical storytelling in the social studies classroom. After briefly noting the value of the historical story in this regard, a specific, ready-made example is provided concerning Truman's decision to use the atomic bomb and includes a crucial set of follow-up…

  12. 40 CFR Appendix E to Subpart S of... - Transient Test Driving Cycle

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Transient Test Driving Cycle E Appendix... Driving Cycle (I) Driver's trace. All excursions in the transient driving cycle shall be evaluated by the... shall cause a test to be void. In addition, provisions shall be available to utilize cycle validation...

  13. Edge Mechanisms for Power Excursion Control in Burning Plasmas

    NASA Astrophysics Data System (ADS)

    Hill, M. D.; Stacey, W. M.

    2017-10-01

    ITER must have active and preferably also passive control mechanisms that will limit inadvertent plasma power excursions which could trigger runaway fusion heating. We are identifying and investigating the potential of ion-orbit loss, impurity seeding, and various divertor ``choking'' phenomena to control or limit sudden increases in plasma density or temperature by reducing energy confinement, increasing radiation loss, etc., with the idea that such mechanisms could be tested on DIII-D and other existing tokamaks. We are assembling an edge-divertor code (GTEDGE-2) with a neutral transport model and a burn dynamics code, for this purpose. One potential control mechanism is the enhanced ion orbit loss from the thermalized ion distribution that would result from heating of the thermalized plasma ion distribution. Another possibility is impurity seeding with ions whose emissivity would increase sharply if the edge temperature increased. Enhanced radiative losses should also reduce the thermal energy flux across the separatrix, perhaps dropping the plasma into the poorer L-mode confinement regime. We will present some initial calculations to quantify these ideas. Work supported by US DOE under DE-FC02-04ER54698.

  14. Disk Disruptions and X-ray Intensity Excursions in Cyg X-2, LMC X-3 and Cyg X-3

    NASA Astrophysics Data System (ADS)

    Boyd, P. T.; Smale, A. P.

    2001-05-01

    The RXTE All Sky Monitor soft X-ray light curves of many X-ray binaries show long-term intensity variations (a.k.a "superorbital periodicities") that have been ascribed to precession of a warped, tilted accretion disk around the X-ray source. We have found that the excursion times between X-ray minima in Cyg X-2 can be characterized as a series of integer multiples of the 9.8 binary orbital period, (as opposed to the previously reported stable 77.7 day single periodicity, or a single modulation whose period changes slowly with time). While the data set is too short for a proper statistical analysis, it is clear that the length of any given intensity excursion cannot be used to predict the next (integer) excursion length in the series. In the black hole candidate system LMC X-3, the excursion times are shown to be related to each other by rational fractions. We find that the long term light curve of the unusual galactic X-ray jet source Cyg X-3 can also be described as a series of intensity excursions related to each other by integer multiples of a fundamental underlying clock. In the latter cases, the clock is apparently not related to the known binary periods. A unified physical model, involving both an inclined accretion disk and a fixed-probability disk disruption mechanism is presented, and compared with three-body scattering results. Each time the disk passes through the orbital plane it experiences a fixed probability P that it will disrupt. This model has testable predictions---the distribution of integers should resemble that of an atomic process with a characteristic half life. Further analysis can support or refute the model, and shed light on what system parameters effectively set the value of P.

  15. Nateglinide and acarbose are comparably effective reducers of postprandial glycemic excursions in chinese antihyperglycemic agent-naive subjects with type 2 diabetes.

    PubMed

    Zhou, Jian; Li, Hong; Zhang, Xiuzhen; Peng, Yongde; Mo, Yifei; Bao, Yuqian; Jia, Weiping

    2013-06-01

    Recent studies have identified postprandial glycemic excursions as risk factors for diabetes complications. This study aimed to compare the effects of nateglinide and acarbose treatments on postprandial glycemic excursions in Chinese subjects with type 2 diabetes. This was a multicenter, open-label, randomized, active-controlled, parallel-group study. One hundred three antihyperglycemic agent-naive subjects with type 2 diabetes (hemoglobin A1c range, 6.5-9.0%) were prospectively recruited from four hospitals in China. The intervention was nateglinide (120 mg three times a day) or acarbose (50 mg three times a day) therapy for 2 weeks. A continuous glucose monitoring system was used to calculate the incremental area under the curve of postprandial blood glucose (AUCpp), the incremental glucose peak (IGP), mean amplitude of glycemic excursions, SD of blood glucose, the mean of daily differences, and 24-h mean blood glucose (MBG). Subjects' serum glycated albumin and the plasma insulin levels were also analyzed. Both agents caused significant reductions on AUCpp and IGP. Similarly, both treatment groups showed significant improvements in the intra- and interday glycemic excursions, as well as the 24-h MBG and serum glycated albumin compared with baseline (P<0.001). However, neither of the agents produced a significantly better effect (P>0.05). Moreover, the nateglinide-treated group had significantly increased insulin levels at 30 min and at 120 min after a standard meal compared with baseline, whereas the acarbose-treated group decreased. No serious adverse events occurred in either group. The rates of hypoglycemic episodes were comparable in the two groups, and no severe hypoglycemic episode occurred in either group. Nateglinide and acarbose were comparably effective in reducing postprandial glycemic excursions in antihyperglycemic agent-naive Chinese patients with type 2 diabetes, possibly through different pathophysiological mechanisms.

  16. Nateglinide and Acarbose Are Comparably Effective Reducers of Postprandial Glycemic Excursions in Chinese Antihyperglycemic Agent–Naive Subjects with Type 2 Diabetes

    PubMed Central

    Zhou, Jian; Li, Hong; Zhang, Xiuzhen; Peng, Yongde; Mo, Yifei; Bao, Yuqian

    2013-01-01

    Abstract Background Recent studies have identified postprandial glycemic excursions as risk factors for diabetes complications. This study aimed to compare the effects of nateglinide and acarbose treatments on postprandial glycemic excursions in Chinese subjects with type 2 diabetes. Subjects and Methods This was a multicenter, open-label, randomized, active-controlled, parallel-group study. One hundred three antihyperglycemic agent–naive subjects with type 2 diabetes (hemoglobin A1c range, 6.5–9.0%) were prospectively recruited from four hospitals in China. The intervention was nateglinide (120 mg three times a day) or acarbose (50 mg three times a day) therapy for 2 weeks. A continuous glucose monitoring system was used to calculate the incremental area under the curve of postprandial blood glucose (AUCpp), the incremental glucose peak (IGP), mean amplitude of glycemic excursions, SD of blood glucose, the mean of daily differences, and 24-h mean blood glucose (MBG). Subjects' serum glycated albumin and the plasma insulin levels were also analyzed. Results Both agents caused significant reductions on AUCpp and IGP. Similarly, both treatment groups showed significant improvements in the intra- and interday glycemic excursions, as well as the 24-h MBG and serum glycated albumin compared with baseline (P<0.001). However, neither of the agents produced a significantly better effect (P>0.05). Moreover, the nateglinide-treated group had significantly increased insulin levels at 30 min and at 120 min after a standard meal compared with baseline, whereas the acarbose-treated group decreased. No serious adverse events occurred in either group. The rates of hypoglycemic episodes were comparable in the two groups, and no severe hypoglycemic episode occurred in either group. Conclusions Nateglinide and acarbose were comparably effective in reducing postprandial glycemic excursions in antihyperglycemic agent–naive Chinese patients with type 2 diabetes, possibly through different pathophysiological mechanisms. PMID:23631607

  17. Mechanisms by which cocoa flavanols improve metabolic syndrome and related disorders.

    PubMed

    Strat, Karen M; Rowley, Thomas J; Smithson, Andrew T; Tessem, Jeffery S; Hulver, Matthew W; Liu, Dongmin; Davy, Brenda M; Davy, Kevin P; Neilson, Andrew P

    2016-09-01

    Dietary administration of cocoa flavanols may be an effective complementary strategy for alleviation or prevention of metabolic syndrome, particularly glucose intolerance. The complex flavanol composition of cocoa provides the ability to interact with a variety of molecules, thus allowing numerous opportunities to ameliorate metabolic diseases. These interactions likely occur primarily in the gastrointestinal tract, where native cocoa flavanol concentration is high. Flavanols may antagonize digestive enzymes and glucose transporters, causing a reduction in glucose excursion, which helps patients with metabolic disorders maintain glucose homeostasis. Unabsorbed flavanols, and ones that undergo enterohepatic recycling, will proceed to the colon where they can exert prebiotic effects on the gut microbiota. Interactions with the gut microbiota may improve gut barrier function, resulting in attenuated endotoxin absorption. Cocoa may also positively influence insulin signaling, possibly by relieving insulin-signaling pathways from oxidative stress and inflammation and/or via a heightened incretin response. The purpose of this review is to explore the mechanisms that underlie these outcomes, critically review the current body of literature related to those mechanisms, explore the implications of these mechanisms for therapeutic utility, and identify emerging or needed areas of research that could advance our understanding of the mechanisms of action and therapeutic potential of cocoa flavanols. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Design of the Core Stage Inter-Tank Umbilical {CSITU) Compliance Mechanism

    NASA Technical Reports Server (NTRS)

    Smith, Kurt R.

    2013-01-01

    Project Goals: a) Design the compliance mechanism for the CSITU system to a 30% level -3D models completed in Pro/Engineer -Relevant design analysis b) Must meet all system requirements and establish basis for proceeding with detailed design. Tasks to be completed: A design that meets requirements for the 30% design review, 01/16/2013. Umbilical arms provide commodities to the launch vehicle prior to T-0. Commodities can range anywhere from hydraulics, pneumatics, cryogenic, electrical, ECS, etc ... Umbilicals commonly employ truss structures to deliver commodities to vehicle. Common configurations include: -Tilt-up -Swing Arm -Hose Drape -Drop Arm Umbilical arms will be mounted to Mobile Launch Platform. SLS currently has 9 T-0 umbilical arms. The compliance refers to the ability of the umbilical to adjust to minor changes in vehicle location. The compliance mechanism refers to the mechanism on the ground support equipment {GSE) that compensates for these changes. For the CSITU, these minor changes, or vehicle excursions, can be up to +4 in. Excursions refer to movements of the vehicle caused by wind loads and thermal expansion. It is ideal to have significant vertical compliance so a passive secondary release mechanism may be implemented.

  19. Human Exploration of Phobos

    NASA Technical Reports Server (NTRS)

    Abercromby, Andrew F. J.; Chappell, Steven P.; Gernhardt, Michael L.; Lee, David E.; Howe, A. Scott

    2015-01-01

    This study developed, analyzed, and compared mission architectures for human exploration of Mars' Moons within the context of an Evolvable Mars Campaign. METHODS: All trades assumed conjunction class missions to Phobos (approximately 500 days in Mars system) as it was considered the driving case for the transportation architecture. All architectures assumed that the Mars Transit Habitat would remain in a High Mars Orbit with crewmembers transferring between HMO and Phobos in a small crew taxi vehicle. A reference science / exploration program was developed including performance of a standard set of tasks at 55 locations on the Phobos surface. Detailed EVA timelines were developed using realistic flight rules to accomplish the reference science tasks using exploration systems ranging from jetpacks to multi-person pressurized excursion vehicles combined with Phobos surface and orbital (L1, L4/L5, 20km Distant Retrograde Orbit) habitat options. Detailed models of propellant mass, crew time, science productivity, radiation exposure, systems and consumables masses, and other figures of merit were integrated to enable quantitative comparison of different architectural options. Options for pre-staging assets using solar electric propulsion (SEP) vs. delivering all systems with the crew were also evaluated. Seven discrete mission architectures were evaluated. RESULTS: The driving consideration for habitat location (Phobos surface vs. orbital) was radiation exposure, with an estimated reduction in cumulative mission radiation exposure of up to 34% (vs. Mars orbital mission) when the habitat is located on the Phobos surface, compared with only 3-6% reduction for a habitat in a 20km DRO. The exploration utility of lightweight unpressurized excursion vehicles was limited by the need to remain within 20 minutes of Solar Particle Event radiation protection combined with complex GN&C systems required by the non-intuitive and highly-variable gravitational environment. Two-person pressurized excursion vehicles as well as mobile surface habitats offer significant exploration capability and operational benefits compared with unpressurized EVA mobility systems at the cost of increased system and propellant mass. Mechanical surface translation modes (i.e. hopping) were modeled and offer potentially significant propellant savings and the possibility of extended exploration operations between crewed missions. Options for extending the utilization of the crew taxi vehicle were examined, including use as an exploration asset for Phobos surface exploration (when combined with an alternate mobility system) and as an EVA platform, both on Phobos and for contingency EVA on the Mars Transit Habitat. CONCLUSIONS: Human exploration of Phobos offers a scientifically meaningful first step towards human Mars surface missions that develops and validates transportation, habitation, and exploration systems and operations in advance of the Mars landing systems.

  20. Interferometer for the measurement of plasma density

    DOEpatents

    Jacobson, Abram R.

    1980-01-01

    An interferometer which combines the advantages of a coupled cavity interferometer requiring alignment of only one light beam, and a quadrature interferometer which has the ability to track multi-fringe phase excursions unambiguously. The device utilizes a Bragg cell for generating a signal which is electronically analyzed to unambiguously determine phase modulation which is proportional to the path integral of the plasma density.

  1. A Late Cambrian Carbon Isotope Excursion Recorded in Passive Margin Dolostones of the Central Appalachian Basin, USA.

    NASA Astrophysics Data System (ADS)

    Mackey, J. E.; Stewart, B. W.

    2016-12-01

    A Late Cambrian global positive carbon isotope excursion, known as the SPICE event [1,2] is linked to possible widespread ocean anoxia and enhanced carbon burial [3,4]. We report data from the central Appalachian Conasauga Group from the upper portion of the Middle Cambrian Maryville limestone, through the Late Cambrian Nolichucky shale and Maynardville limestone members. A geochemical, macro-, and micro-scale analyses of core material from southeastern Ohio was carried out to further constrain the timing of oceanic anoxia and trace element geochemistry relative to sediment fluxes occurring at the transition of the Middle to Late Cambrian. The section represents condensed, passive margin shale deposition and carbonate ramp development on the continental shelf of Laurentia. Carbonate sediments (primarily diagenetic dolomite) record a positive δ13C (relative to V-PDB) excursion starting in the upper Nolichucky shale member, reaching its peak (+4.0) in the overlying Maynardville limestone. At this location, there is an offset between the onlap Nolichucky shale deposition and start of the C isotope excursion; this was reported as well in a carbonate section further south of this location [2], on the other side of an extensional feature (Rome Trough) that formed a deep marine basin during Cambrian time. The condensed shale package and relatively low TOC content in our samples is likely due to the combination of a shallow, upslope basin location and isostatic influence on passive margin sedimentation. However, within the Rome Trough, the Nolichucky shale is rich in organic carbon and a recent target of hydrocarbon exploration. The data suggest a possible link between deposition of this shale and the global SPICE event. The robustness of the Late Cambrian δ13C excursion in diagenetically altered sediments and association with hydrocarbon bearing units indicates its utility as a stratigraphic indicator and as a target for exploration. Ongoing geochemical work will focus on trace element and isotopic signatures preserved in the carbonate portion of sediments spanning the C isotope excursion. Refs: [1] Saltzman et al., 1998, Geol. Soc. Am. Bull. 110, 285-297; [2] Glumac and Walker, 1998, J. Sed. Res. 68, 1212-1222; [3] Hurtgen et al., 2009, Earth Planet. Sci. Lett. 281, 288-297; [4] Gill et al., 2011, Nature 469, 80-83.

  2. Age and Structure of the Laschamp Geomagnetic Excursion

    NASA Astrophysics Data System (ADS)

    Scaillet, S.; Laj, C.; Kissel, C.; Guillou, H.; Singer, B. S.

    2004-12-01

    The age of the Laschamp geomagnetic excursion has been recently re-investigated using unspiked K/Ar and Ar/Ar techniques (Guillou et al., Session V01, this conference). The new age determination of 40.4 +/- 2.0 ka (2 sigma) is more precise than those previously reported in the literature and agrees precisely with that deduced from the GLOPIS-75 sedimentary paleointensity stack calibrated against the GISP2 ice core chronology. Two of the North Atlantic cores used in GLOPIS-75 (MD95-2034 and PS2644-5) yield rather detailed transitional VGP paths. In the two cases the paths show large similarities, with the VGP initially descending along mid-western Pacific, then returning to normal polarities with a large clockwise loop over Africa and Europe. Differences in the highest southern latitudes reached by the VGP can be explained assuming more different degrees of smearing of the paleomagnetic record due to differences in sedimentation rate in the two cores. In the most detailed record, MD95-2034 , two smaller loops are present preceding the main excursion. In the two cores, the excursion is characterized by a significant drop in intensity. The reversal paths observed for the Laschamp event are very close in position to those reported for the Icelandic Basin Event (IBE) from sites in the North Atlantic and the South China Sea (Laj et al., this conference) but differ in the sense of looping: while a clockwise loop is observed here, a counterclockwise loop is observed for the IBE. Despite this difference, the similarity of the transitional records tends to suggest that a similar, relatively simple, geometry has dominated the two excursions and therefore that similar dynamo mechanisms have prevailed during the reversal process.

  3. Constraints on Early Triassic carbon cycle dynamics from paired organic and inorganic carbon isotope records

    NASA Astrophysics Data System (ADS)

    Meyer, K. M.; Yu, M.; Lehrmann, D.; van de Schootbrugge, B.; Payne, J. L.

    2013-01-01

    Large δ13C excursions, anomalous carbonate precipitates, low diversity assemblages of small fossils, and evidence for marine euxinia in uppermost Permian and Lower Triassic strata bear more similarity to Neoproterozoic carbonates than to the remainders of the Permian and Triassic systems. Middle Triassic diversification of marine ecosystems coincided with the waning of anoxia and stabilization of the global carbon cycle, suggesting that environment-ecosystem linkages were important to biological recovery. However, the Earth system behavior responsible for these large δ13C excursions remains poorly constrained. Here we present a continuous Early Triassic δ13Corg record from south China and use it to test the extent to which Early Triassic excursions in δ13Ccarb record changes in the δ13C of marine dissolved inorganic carbon (DIC). Regression analysis demonstrates a significant positive correlation between δ13Corg and δ13Ccarb across multiple sections that span a paleoenvironmental gradient. Such a correlation is incompatible with diagenetic alteration because no likely mechanism will alter both δ13Corg and δ13Ccarb records in parallel and therefore strongly indicates a primary depositional origin. A simple explanation for this correlation is that a substantial portion of the preserved Corg was derived from the contemporaneous DIC pool, implying that the observed excursions reflect variation in the δ13C of the exogenic carbon reservoir (ocean, atmosphere, biomass). These findings support existing evidence that large δ13C excursions are primary and therefore strengthen the case that large-scale changes to the carbon cycle were mechanistically linked to the low diversity and small size of Early Triassic fossils. Associated sedimentary and biogeochemical phenomena further suggest that similar associations in Neoproterozoic and Cambrian strata may reflect the same underlying controls.

  4. An investigation of the dynamic relationship between navicular drop and first metatarsophalangeal joint dorsal excursion

    PubMed Central

    Griffin, Nicole L; Miller, Charlotte; Schmitt, Daniel; D'Août, Kristiaan

    2013-01-01

    The modern human foot is a complex biomechanical structure that must act both as a shock absorber and as a propulsive strut during the stance phase of gait. Understanding the ways in which foot segments interact can illuminate the mechanics of foot function in healthy and pathological humans. It has been proposed that increased values of medial longitudinal arch deformation can limit metatarsophalangeal joint excursion via tension in the plantar aponeurosis. However, this model has not been tested directly in a dynamic setting. In this study, we tested the hypothesis that during the stance phase, subtalar pronation (stretching of the plantar aponeurosis and subsequent lowering of the medial longitudinal arch) will negatively affect the amount of first metatarsophalangeal joint excursion occurring at push-off. Vertical descent of the navicular (a proxy for subtalar pronation) and first metatarsophalangeal joint dorsal excursion were measured during steady locomotion over a flat substrate on a novel sample consisting of asymptomatic adult males and females, many of whom are habitually unshod. Least-squares regression analyses indicated that, contrary to the hypothesis, navicular drop did not explain a significant amount of variation in first metatarsophalangeal joint dorsal excursion. These results suggest that, in an asymptomatic subject, the plantar aponeurosis and the associated foot bones can function effectively within the normal range of subtalar pronation that takes place during walking gait. From a clinical standpoint, this study highlights the need for investigating the in vivo kinematic relationship between subtalar pronation and metatarsophalangeal joint dorsiflexion in symptomatic populations, and also the need to explore other factors that may affect the kinematics of asymptomatic feet. PMID:23600634

  5. Practices and Methods for Actualization of the Scientific Information in Art Excursions (Excursions and Cultural Heritage in the Contemporary World)

    ERIC Educational Resources Information Center

    Portnova, Tatiana V.

    2016-01-01

    The paper deals with various practices and methods for actualization of the scientific information in art excursions. The modern society is characterized by commitment to information richness. The range of cultural and historical materials used as the basis for art excursions is really immense. However if to consider the number of excursions with…

  6. Scalar excursions in large-eddy simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matheou, Georgios; Dimotakis, Paul E.

    Here, the range of values of scalar fields in turbulent flows is bounded by their boundary values, for passive scalars, and by a combination of boundary values, reaction rates, phase changes, etc., for active scalars. The current investigation focuses on the local conservation of passive scalar concentration fields and the ability of the large-eddy simulation (LES) method to observe the boundedness of passive scalar concentrations. In practice, as a result of numerical artifacts, this fundamental constraint is often violated with scalars exhibiting unphysical excursions. The present study characterizes passive-scalar excursions in LES of a shear flow and examines methods formore » diagnosis and assesment of the problem. The analysis of scalar-excursion statistics provides support of the main hypothesis of the current study that unphysical scalar excursions in LES result from dispersive errors of the convection-term discretization where the subgrid-scale model (SGS) provides insufficient dissipation to produce a sufficiently smooth scalar field. In the LES runs three parameters are varied: the discretization of the convection terms, the SGS model, and grid resolution. Unphysical scalar excursions decrease as the order of accuracy of non-dissipative schemes is increased, but the improvement rate decreases with increasing order of accuracy. Two SGS models are examined, the stretched-vortex and a constant-coefficient Smagorinsky. Scalar excursions strongly depend on the SGS model. The excursions are significantly reduced when the characteristic SGS scale is set to double the grid spacing in runs with the stretched-vortex model. The maximum excursion and volume fraction of excursions outside boundary values show opposite trends with respect to resolution. The maximum unphysical excursions increase as resolution increases, whereas the volume fraction decreases. The reason for the increase in the maximum excursion is statistical and traceable to the number of grid points (sample size) which increases with resolution. In contrast, the volume fraction of unphysical excursions decreases with resolution because the SGS models explored perform better at higher grid resolution.« less

  7. Scalar excursions in large-eddy simulations

    DOE PAGES

    Matheou, Georgios; Dimotakis, Paul E.

    2016-08-31

    Here, the range of values of scalar fields in turbulent flows is bounded by their boundary values, for passive scalars, and by a combination of boundary values, reaction rates, phase changes, etc., for active scalars. The current investigation focuses on the local conservation of passive scalar concentration fields and the ability of the large-eddy simulation (LES) method to observe the boundedness of passive scalar concentrations. In practice, as a result of numerical artifacts, this fundamental constraint is often violated with scalars exhibiting unphysical excursions. The present study characterizes passive-scalar excursions in LES of a shear flow and examines methods formore » diagnosis and assesment of the problem. The analysis of scalar-excursion statistics provides support of the main hypothesis of the current study that unphysical scalar excursions in LES result from dispersive errors of the convection-term discretization where the subgrid-scale model (SGS) provides insufficient dissipation to produce a sufficiently smooth scalar field. In the LES runs three parameters are varied: the discretization of the convection terms, the SGS model, and grid resolution. Unphysical scalar excursions decrease as the order of accuracy of non-dissipative schemes is increased, but the improvement rate decreases with increasing order of accuracy. Two SGS models are examined, the stretched-vortex and a constant-coefficient Smagorinsky. Scalar excursions strongly depend on the SGS model. The excursions are significantly reduced when the characteristic SGS scale is set to double the grid spacing in runs with the stretched-vortex model. The maximum excursion and volume fraction of excursions outside boundary values show opposite trends with respect to resolution. The maximum unphysical excursions increase as resolution increases, whereas the volume fraction decreases. The reason for the increase in the maximum excursion is statistical and traceable to the number of grid points (sample size) which increases with resolution. In contrast, the volume fraction of unphysical excursions decreases with resolution because the SGS models explored perform better at higher grid resolution.« less

  8. Mid-Brunhes magnetic excursions in marine isotope stages 9, 13, 14, and 15 (286, 495, 540, and 590 ka) at North Atlantic IODP Sites U1302/3, U1305, and U1306

    NASA Astrophysics Data System (ADS)

    Channell, J. E. T.

    2017-02-01

    Integrated Ocean Drilling Program (IODP) Site U1302/3 (Orphan Knoll, off Newfoundland) recorded magnetic excursions in marine isotope stages (MIS) 9a (at 286 ka) and 13a (at 495 ka). Sites U1306 and U1305 (Eirik Drift, off SE Greenland) record excursions in MIS 14a/b (at 540 ka) and 15b/c (at 590 ka). In the excursion intervals, magnetic measurements of continuous "u-channel" samples from multiple holes within site are augmented by measurements of cubic (8 cm3) discrete samples. The excursions lie in relative paleointensity (RPI) minima at each site and in RPI reference stacks, and correspond to dated intervals of 10Be overproduction in other deep-sea sediment records. Although observed at multiple holes at each site, and from u-channel and discrete samples, the excursions are not observed at all three sites, and often at only one of the three sites. Sporadic recording of these magnetic excursions, and excursions in general, is attributed to a combination of filtering by the process of acquisition of detrital remanent magnetization (DRM), postdepositional overprint of weak excursion magnetizations, the millennial or even centennial duration of directional excursions, and nonuniform sedimentation rates at these timescales in North Atlantic sediment drifts.

  9. High-resolution palaeomagnetic records of the Laschamp geomagnetic excursion from the Blake Ridge

    NASA Astrophysics Data System (ADS)

    Mac Niocaill, C.; Bourne, M. D.; Thomas, A. L.; Henderson, G. M.

    2013-05-01

    Geomagnetic excursions are brief (1000s of years) deviations in geomagnetic field behaviour from that expected during 'normal secular' variation. The Laschamp excursion (~41 ka) was a global deviation in geomagnetic field behaviour. Previously published records suggest rapid changes in field direction and a concurrent substantial decrease in field intensity. Accurate dating of excursions and determinations of their durations from multiple locations is vital to our understanding to global field behaviour during these deviations. We present here high-resolution palaeomagnetic records of the Laschamp excursion obtained from two Ocean Drilling Program (ODP) Sites 1061 and 1062 on the Blake-Bahama Outer Ridge (ODP Leg 172) Relatively high sedimentation rates (~30-40 cm kyr-1) at these locations allow the determination of transitional field behaviour during the excursion. Despite their advantages, sedimentary records can be limited by the potential for unrecognized variations in sedimentation rates between widely spaced age-constrained boundaries. Rather than assuming a constant sedimentation rate between assigned age tie-points, we employ measurements of the concentration of 230Thxs in the sediment. 230Thxs is a constant flux proxy and may be used to assess variations in the sedimentation rates through the core sections of interest. Following this approach, we present a new age model for Site 1061 that allows us to better determine the temporal behaviour of the Laschamp excursion with greater accuracy and known uncertainty. Palaeomagnetic measurements of discrete samples from four cores reveal a single excursional feature, across an interval of 30 cm, associated with a broader palaeointensity low. The excursion is characterised by rapid transitions (less than 200 years) between a stable normal polarity and a partially-reversed, polarity. Peaks in inclination either side of the directional excursion indicate periods of time when the local field is dominated by vertical flux patches. Similar behaviour has been observed in records of the Iceland Basin Excursion from the same region. The palaeointensity record is in good agreement between the two sites. The palaeointensity record shows two prominent minima, the first associated with the Laschamp excursion at 41 ka and the second at ~34 ka, possibly associated with the elusive 'Mono-Lake' excursion. Similar field intensity behaviour has been observed during the Blake excursion suggesting that the geomagnetic field stability may be reduced for relatively long durations, potentially up to tens of thousands of years. Using the 230Thxs derived sedimentation rate, we determine that the directional excursion at this location was no longer than ~400 years, occurring within a palaeointensity low lasting 2000 years. We compare this record with previously published records of the Blake and Iceland Basin Excursions from nearby locations. The Laschamp excursion at this location appears to be much shorter in duration than the Blake and Iceland Basin excursions.

  10. High-resolution palaeomagnetic records of the Laschamp geomagnetic excursion from ODP Sites 1061 and 1062

    NASA Astrophysics Data System (ADS)

    Bourne, M. D.; Henderson, G. M.; Thomas, A. L.; Mac Niocaill, C.

    2012-12-01

    The Laschamp geomagnetic excursion (~41 ka) was a brief global deviation in geomagnetic field behaviour from that expected during normal secular variation. Previously published records suggest rapid changes in field direction and a concurrent substantial decrease in field intensity. We present here high-resolution palaeomagnetic records of the Laschamp excursion obtained from two Ocean Drilling Program (ODP) Sites 1061 and 1062 on the Blake-Bahama Outer Ridge (ODP Leg 172) and compare this record with previously published records of the Blake and Iceland Basin Excursions. Relatively high sedimentation rates (>10 cm kyr-1) at these locations allow the determination of transitional field behaviour during the excursion. Rather than assuming a constant sedimentation rate between assigned age tie-points, we employ measurements of 230Thxs concentration in the sediment to assess variations in the sedimentation rates through the core sections of interest. This allows us to better determine the temporal behaviour of the Laschamp excursion with greater accuracy and known uncertainty. The Laschamp excursion at this location appears to be much shorter in duration than the Blake and Iceland Basin excursions. Palaeomagnetic measurements of discrete samples from four cores reveal a single excursional feature, across an interval of 30 cm, associated with a broader palaeointensity low. The excursion is characterised by rapid transitions (less than 500 years) between a stable normal polarity and a partially-reversed, polarity. Peaks in inclination either side of the directional excursion indicate periods of time when the local field is dominated by vertical flux patches. Similar behaviour has been observed in records of the Iceland Basin Excursion from the same region. The palaeointensity record is in good agreement between the two sites. The palaeointensity record shows two minima, where the second dip in intensity is associated with a more limited directional deviation. Similar field intensity behaviour has been observed during the Blake excursion suggesting that the geomagnetic field stability may be reduced for relatively long durations, potentially up to tens of thousands of years.

  11. A COCHLEAR MODEL USING THE TIME-AVERAGED LAGRANGIAN AND THE PUSH-PULL MECHANISM IN THE ORGAN OF CORTI.

    PubMed

    Yoon, Yongjin; Puria, Sunil; Steele, Charles R

    2009-09-05

    In our previous work, the basilar membrane velocity V(BM) for a gerbil cochlea was calculated and compared with physiological measurements. The calculated V(BM) showed excessive phase excursion and, in the active case, a best-frequency place shift of approximately two fifths of an octave higher. Here we introduce a refined model that uses the time-averaged Lagrangian for the conservative system to resolve the phase excursion issues. To improve the overestimated best-frequency place found in the previous feed-forward active model, we implement in the new model a push-pull mechanism from the outer hair cells and phalangeal process. Using this new model, the V(BM) for the gerbil cochlea was calculated and compared with animal measurements, The results show excellent agreement for mapping the location of the maximum response to frequency, while the agreement for the response at a fixed point as a function of frequency is excellent for the amplitude and good for the phase.

  12. A COCHLEAR MODEL USING THE TIME-AVERAGED LAGRANGIAN AND THE PUSH-PULL MECHANISM IN THE ORGAN OF CORTI

    PubMed Central

    YOON, YONGJIN; PURIA, SUNIL; STEELE, CHARLES R.

    2010-01-01

    In our previous work, the basilar membrane velocity VBM for a gerbil cochlea was calculated and compared with physiological measurements. The calculated VBM showed excessive phase excursion and, in the active case, a best-frequency place shift of approximately two fifths of an octave higher. Here we introduce a refined model that uses the time-averaged Lagrangian for the conservative system to resolve the phase excursion issues. To improve the overestimated best-frequency place found in the previous feed-forward active model, we implement in the new model a push-pull mechanism from the outer hair cells and phalangeal process. Using this new model, the VBM for the gerbil cochlea was calculated and compared with animal measurements, The results show excellent agreement for mapping the location of the maximum response to frequency, while the agreement for the response at a fixed point as a function of frequency is excellent for the amplitude and good for the phase. PMID:20485540

  13. A Whale of an Interest in Sea Creatures: The Learning Potential of Excursions

    ERIC Educational Resources Information Center

    Hedges, Helen

    2004-01-01

    Excursions, or field trips, are a common component of early childhood programs, seen as a means of enriching the curriculum by providing experiences with people, places, and things in the community. Although excursions have been used as a framework for research on children's memory development, research on the efficacy of excursions in terms of…

  14. The effect of muscle excursion on muscle recovery after tendon repair in a neglected tendon injury: a study in rabbit soleus muscles.

    PubMed

    Jeon, Suk Ha; Chung, Moon Sang; Baek, Goo Hyun; Lee, Young Ho; Gong, Hyun Sik

    2011-01-01

    We attempted to determine whether muscle excursion observed during operation can be a prognostic indicator of muscle recovery after delayed tendon repair in a rabbit soleus model. Eighteen rabbits underwent tenotomy of the soleus muscles bilaterally and were divided into three groups according to the period from tenotomy to repair. The tendons of each group were repaired 2, 4, and 6 weeks after tenotomy. The excursion of each soleus muscle was measured at the time of tenotomy (baseline), at 2, 4, 6 weeks after tenotomy, and 8 weeks after tendon repair. The amount of muscle recovery after tendon repair in terms of muscle excursion independently depended on the timing of repair and on the muscle excursion observed during repair. The regression model predicted that the muscle excursion recovered on average by 0.6% as the muscle excursion at the time of repair increased by 1% after adjusting for the timing of repair. This study suggests that measuring the muscle excursion during tendon repair may help physicians estimate the potential of muscle recovery in cases of delayed tendon repair. Copyright © 2010 Orthopaedic Research Society.

  15. Visual evidence of the Sterno-Etrussia geomagnetic excursion (~2700 BP)?

    NASA Astrophysics Data System (ADS)

    Raspopov, O. M.; Dergachev, V. A.; Goos'kova, E. G.; Morner, N.-A.

    2003-04-01

    In the Bible's Old Testament Book of Ezekiel there is a description of the Ezekiel's vision of "a great cloud with brightness round about it" to the north of the observation site. The event described in the Bible occurred in 593 BC, i.e., approximately 2600 years ago. Ezekiel was at that time approximately 100 km south of Babylon (latitude ~ 32 N, longitude ~ 45 E). Auroral specialists interpret the Ezekiel's vision as observation of coronal auroral displays at low latitudes. However, to support this hypothesis, it is necessary to understand the physical mechanism responsible for generation of these forms of auroras at low latitudes. Analysis of palaeo- and archaeomagnetic data, including our data on magnetic properties of sediments of the Barents and White Seas and the literature data, has shown that about 2700 BP, i.e., in Ezekiel's time, development of a geomagnetic "Sterno-Etrussia" excursion took place. The duration of the excursion during which the northern geomagnetic pole wandered to the Southern Hemisphere was no more than 200-300 years. Manifestations of this excursion were found in 16 regions of the Eurasian continent and adjacent seas and also in the North and South America. By plotting the path along which the northern geomagnetic pole wandered to the southern latitudes during this excursion on the basis of palaeomagnetic data, we have found that it wandered in the longitude sector plus or minus 30 degrees, and about 2700 BP the northern geomagnetic pole was at the longitude close to the Babylon longitude, where Ezekiel had his vision. Thus, at that time Babylon was at high geomagnetic latitudes where regular coronal auroral displays occur. Records of observation of the unusual brightness of the sky in the V-VI centuries BC can also be found in Greek chronicles. This indicates that the Ezekiel's vision was not the only observation of auroras at low latitudes during the period considered here. This work was supported by INTAS, Grant 97-31008 and PFBR, Grant 00-05-64921.

  16. The Excursion Set Theory of Halo Mass Functions, Halo Clustering, and Halo Growth

    NASA Astrophysics Data System (ADS)

    Zentner, Andrew R.

    I review the excursion set theory with particular attention toward applications to cold dark matter halo formation and growth, halo abundance, and halo clustering. After a brief introduction to notation and conventions, I begin by recounting the heuristic argument leading to the mass function of bound objects given by Press and Schechter. I then review the more formal derivation of the Press-Schechter halo mass function that makes use of excursion sets of the density field. The excursion set formalism is powerful and can be applied to numerous other problems. I review the excursion set formalism for describing both halo clustering and bias and the properties of void regions. As one of the most enduring legacies of the excursion set approach and one of its most common applications, I spend considerable time reviewing the excursion set theory of halo growth. This section of the review culminates with the description of two Monte Carlo methods for generating ensembles of halo mass accretion histories. In the last section, I emphasize that the standard excursion set approach is the result of several simplifying assumptions. Dropping these assumptions can lead to more faithful predictions and open excursion set theory to new applications. One such assumption is that the height of the barriers that define collapsed objects is a constant function of scale. I illustrate the implementation of the excursion set approach for barriers of arbitrary shape. One such application is the now well-known improvement of the excursion set mass function derived from the "moving" barrier for ellipsoidal collapse. I also emphasize that the statement that halo accretion histories are independent of halo environment in the excursion set approach is not a general prediction of the theory. It is a simplifying assumption. I review the method for constructing correlated random walks of the density field in the more general case. I construct a simple toy model to illustrate that excursion set theory (with a constant barrier height) makes a simple and general prediction for the relation between halo accretion histories and the large-scale environments of halos: regions of high density preferentially contain late-forming halos and conversely for regions of low density. I conclude with a brief discussion of the importance of this prediction relative to recent numerical studies of the environmental dependence of halo properties.

  17. A Comparison of two Brunhes Chron Geomagnetic Excursions Recorded by Neighbouring North Atlantic Sites (ODP Sites 1062 and 1063)

    NASA Astrophysics Data System (ADS)

    Bourne, M.; Mac Niocaill, C.; Knudsen, M. F.; Thomas, A. L.; Henderson, G. M.

    2012-04-01

    A full picture of geomagnetic field behaviour during the Blake excursion is currently limited by a paucity of robust, high-resolution records of this ambiguous event. Some records seem to point towards a 'double-excursion' character whilst others fail to record the Blake excursion at all. We present here a high-resolution record of the Blake excursion obtained from Ocean Drilling Program (ODP) Site 1062 on the Blake Outer Ridge (ODP Leg 172). Palaeomagnetic measurements in three cores reveal a single excursional feature associated with a broad palaeointensity low, characterised by rapid transitions (less than 500 years) between a stable normal polarity and a fully-reversed, pseudo-stable polarity. A relatively high sedimentation rate (~10 cm kyr-1) allows the determination of transitional field behaviour during the excursion. Rather than assuming a constant sedimentation rate between assigned age tie-points, we employ measurements of 230Thxs concentrations in the sediment to assess variations in the sedimentation rates through the core sections of interest. This allows us to determine an age and duration for the two excursions with greater accuracy and known uncertainty. Our new age model gives an age of 127 ka for the midpoint of the Blake event at Site 1062. The age model also gives a duration for the directional excursion of 7.1±1.6 kyr. This duration is similar to that previously reported for the Iceland Basin Excursion (~185 ka) from the nearby Bermuda Rise (ODP Site 1063), which recorded a ~7-8 kyr event. Similarly, a high sedimentation rate (10-15 cm kyr-1) at this site allows a high-resolution reconstruction of the geomagnetic field behaviour during the Iceland Basin Excursion. The Site 1063 palaeomagnetic record suggests more complicated behaviour than that of the Blake excursion at Site 1062. Instead, transitional VGP paths are characterised by stop-and-go behaviour between VGP clusters that may be related to long-standing thermo-dynamic features of the core-mantle system. The long duration of fully reversed directions at the two sites is somewhat longer than that typically assumed for excursions and appears to suggest that there may be a degree of stability associated with the two excursional events. We will present a comparison of the geomagnetic field behaviour of the two excursions as recorded at these two sites.

  18. In search of mitochondrial mechanisms: interfield excursions between cell biology and biochemistry.

    PubMed

    Bechtel, William; Abrahamsen, Adele

    2007-01-01

    Developing models of biological mechanisms, such as those involved in respiration in cells, often requires collaborative effort drawing upon techniques developed and information generated in different disciplines. Biochemists in the early decades of the 20th century uncovered all but the most elusive chemical operations involved in cellular respiration, but were unable to align the reaction pathways with particular structures in the cell. During the period 1940-1965 cell biology was emerging as a new discipline and made distinctive contributions to understanding the role of the mitochondrion and its component parts in cellular respiration. In particular, by developing techniques for localizing enzymes or enzyme systems in specific cellular components, cell biologists provided crucial information about the organized structures in which the biochemical reactions occurred. Although the idea that biochemical operations are intimately related to and depend on cell structures was at odds with the then-dominant emphasis on systems of soluble enzymes in biochemistry, a reconceptualization of energetic processes in the 1960s and 1970s made it clear why cell structure was critical to the biochemical account. This paper examines how numerous excursions between biochemistry and cell biology contributed a new understanding of the mechanism of cellular respiration.

  19. Three-dimensional skeletal kinematics of the shoulder girdle and forelimb in walking Alligator

    PubMed Central

    Baier, David B; Gatesy, Stephen M

    2013-01-01

    Crocodylians occupy a key phylogenetic position for investigations of archosaur locomotor evolution. Compared to the well-studied hindlimb, relatively little is known about the skeletal movements and mechanics of the forelimb. In this study, we employed manual markerless XROMM (X-ray Reconstruction Of Moving Morphology) to measure detailed 3-D kinematics of the shoulder girdle and forelimb bones of American alligators (Alligator mississippiensis) walking on a treadmill. Digital models of the interclavicle, scapulocoracoid, humerus, radius and ulna were created using a 3-D laser scanner. Models were articulated and aligned to simultaneously recorded frames of fluoroscopic and standard light video to reconstruct and measure joint motion. Joint coordinate systems were established for the coracosternal, glenohumeral and elbow joints. Our analysis revealed that the limb joints only account for about half of fore/aft limb excursion; the remaining excursion results from shoulder girdle movements and lateral bending of the vertebral column. Considerable motion of each scapulocoracoid relative to the vertebral column is consistent with coracosternal mobility. The hemisellar design of the glenohumeral joint permits some additional translation, or sliding in the fore-aft plane, but this movement does not have much of an effect on the distal excursion of the bone. PMID:24102540

  20. The effect of spinal position on sciatic nerve excursion during seated neural mobilisation exercises: an in vivo study using ultrasound imaging

    PubMed Central

    Ellis, Richard; Osborne, Samantha; Whitfield, Janessa; Parmar, Priya; Hing, Wayne

    2017-01-01

    Objectives Research has established that the amount of inherent tension a peripheral nerve tract is exposed to influences nerve excursion and joint range of movement (ROM). The effect that spinal posture has on sciatic nerve excursion during neural mobilisation exercises has yet to be determined. The purpose of this research was to examine the influence of different sitting positions (slump-sitting versus upright-sitting) on the amount of longitudinal sciatic nerve movement during different neural mobilisation exercises commonly used in clinical practice. Methods High-resolution ultrasound imaging followed by frame-by-frame cross-correlation analysis was used to assess sciatic nerve excursion. Thirty-four healthy participants each performed three different neural mobilisation exercises in slump-sitting and upright-sitting. Means comparisons were used to examine the influence of sitting position on sciatic nerve excursion for the three mobilisation exercises. Linear regression analysis was used to determine whether any of the demographic data represented predictive variables for longitudinal sciatic nerve excursion. Results There was no significant difference in sciatic nerve excursion (across all neural mobilisation exercises) observed between upright-sitting and slump-sitting positions (P = 0.26). Although greater body mass index, greater knee ROM and younger age were associated with higher levels of sciatic nerve excursion, this model of variables offered weak predictability (R2 = 0.22). Discussion Following this study, there is no evidence that, in healthy people, longitudinal sciatic nerve excursion differs significantly with regards to the spinal posture (slump-sitting and upright-sitting). Furthermore, although some demographic variables are weak predictors, the high variance suggests that there are other unknown variables that may predict sciatic nerve excursion. It can be inferred from this research that clinicians can individualise the design of seated neural mobilisation exercises, using different seated positions, based upon patient comfort and minimisation of neural mechanosensitivity with the knowledge that sciatic nerve excursion will not be significantly influenced. PMID:28559669

  1. Guidelines for Out-of-School Experiences.

    ERIC Educational Resources Information Center

    Queen's Univ., Kingston (Ontario). Science Resource Centre.

    As a mechanism by which policy for out-of-school experiences is carried out, these guidelines developed for Bruce County Schools, Canada, in 1972-73 are intended to insure pupil safety and set forth teacher responsibility during educational outings and excursions for students of all levels. Included are administrative procedures for obtaining…

  2. Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    PubMed

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-04-17

    Impairments in dynamic balance have a detrimental effect in older adults at risk of falls (OARF). Gait initiation (GI) is a challenging transitional movement. Centre of pressure (COP) excursions using force plates have been used to measure GI performance. The Nintendo Wii Balance Board (WBB) offers an alternative to a standard force plate for the measurement of CoP excursion. To determine the reliability of COP excursions using the WBB, and its feasibility within a 4-week strength and balance intervention (SBI) treating OARF. Ten OARF subjects attending SBI and ten young healthy adults, each performed three GI trials after 10 s of quiet stance from a standardised foot position (shoulder width) before walking forward 3 m to pick up an object. Averaged COP mediolateral (ML) and anteroposterior (AP) excursions (distance) and path-length time (GI-onset to first toe-off) were analysed. WBB ML (0.866) and AP COP excursion (0.895) reliability (ICC 3,1 ) was excellent, and COP path-length reliability was fair (0.517). Compared to OARF, healthy subjects presented with larger COP excursion in both directions and shorter COP path length. OARF subjects meaningfully improved their timed-up-and-go and ML COP excursion between weeks 1-4, while AP COP excursions, path length, and confidence-in-balance remained stable. COP path length and excursion directions probably measure different GI postural control attributes. Limitations in WBB accuracy and precision in transition tasks needs to be established before it can be used clinically to measure postural aspects of GI viably. The WBB could provide valuable clinical evaluation of balance function in OARF.

  3. Point-of-care sonographic detection of left endobronchial main stem intubation and obstruction versus endotracheal intubation.

    PubMed

    Blaivas, Michael; Tsung, James W

    2008-05-01

    Determining the correct position of endotracheal tubes in critically ill patients may be complicated by external factors such as noise, body habitus, and the need for ongoing resuscitation. Multiple detection techniques have been developed to determine the correct endotracheal tube position, recently including the use of sonography to evaluate lung expansion and diaphragmatic excursion. These techniques have also been applied to diagnosis of right endobronchial main stem intubation, which may be confused with a unilateral pneumothorax in some cases. We describe the sonographic findings in a case series of endobronchial main stem intubations and obstruction, highlighting the utility of this sonographic application. Previous literature and future applications are discussed. Sonographic detection of the sliding lung sign, the lung pulse, and diaphragmatic excursion can accurately detect main stem bronchial intubation as well as bronchial obstruction. Clinical use of lung sonography may decrease the need for chest radiography and may allow more rapid diagnosis of main stem intubation and bronchial obstruction.

  4. Design of equipment for lunar dust removal

    NASA Technical Reports Server (NTRS)

    Belden, Lacy; Cowan, Kevin; Kleespies, Hank; Ratliff, Ryan; Shah, Oniell; Shelburne, Kevin

    1991-01-01

    NASA has a long range goal of constructing a fully equipped, manned lunar base on the near side of the moon by the year 2015. During the Apollo Missions, lunar dust coated and fouled equipment surfaces and mechanisms exposed to the lunar environment. In addition, the atmosphere and internal surfaces of the lunar excursion module were contaminated by lunar dust which was brought in on articles passed through the airlock. Consequently, the need exists for device or appliance to remove lunar dust from surfaces of material objects used outside of the proposed lunar habitat. Additionally, several concepts were investigated for preventing the accumulation of lunar dust on mechanisms and finished surfaces. The character of the dust and the lunar environment present unique challenges for the removal of contamination from exposed surfaces. In addition to a study of lunar dust adhesion properties, the project examines the use of various energy domains for removing the dust from exposed surfaces. Also, prevention alternatives are examined for systems exposed to lunar dust. A concept utilizing a pressurized gas is presented for dust removal outside of an atmospherically controlled environment. The concept consists of a small astronaut/robotic compatible device which removes dust from contaminated surfaces by a small burst of gas.

  5. Taking the pulse of the carbon release during the onset of the Paleocene-Eocene thermal maximum

    NASA Astrophysics Data System (ADS)

    Babila, T. L.; Bralower, T. J.; Robinson, M. M.; Self-Trail, J. M.; Zachos, J. C.

    2015-12-01

    The Paleocene-Eocene thermal maximum (PETM) (~55 Ma) is a warming event characterized by a negative carbon isotope excursion (CIE) representing a large and rapid injection of carbon into global reservoirs. Debate continues regarding the mechanism, magnitude, and tempo of the carbon released. A few terrestrial and marine sediment records document two distinct δ13C excursions a pre-onset excursion (POE) and CIE interpreted as evidence of multiple carbon injections. We generated geochemical records of ocean carbonate chemistry and temperature using cores drilled by the U.S Geological Survey (USGS) that recovered expanded sections of the PETM onset along the mid-Atlantic coastal plain. Our stable isotope (δ13C and δ18O) planktonic foraminifer records from South Dover Bridge (SDB), Maryland USA exhibit prominent anomalies across the Paleocene-Eocene boundary consistent to proximal coastal sites. δ13C records of mixed-layer (Acarinina spp.) and thermocline (Subbotina spp.) dwelling planktonic foraminifera show two negative carbon excursions that include a 2 ‰ POE and 3-4 ‰ CIE that return to baseline values between events in conjunction with bulk carbonate trends. Remarkably, contemporaneous foraminifer δ18O records exhibit only a minor response during the POE. This could be an artifact of preservation, or at face value, indicative of little to no warming. For the latter, this would require a rapid, but relatively small carbon release. To test the coupled link between atmosphere and surface ocean δ13C records we aim to integrate our geochemical results with model simulations to establish the duration and global extent of multiple carbon releases.

  6. The effects of texting on driving performance in a driving simulator: the influence of driver age.

    PubMed

    Rumschlag, Gordon; Palumbo, Theresa; Martin, Amber; Head, Doreen; George, Rajiv; Commissaris, Randall L

    2015-01-01

    Distracted driving is a significant contributor to motor vehicle accidents and fatalities, and texting is a particularly significant form of driver distraction that continues to be on the rise. The present study examined the influence of driver age (18-59 years old) and other factors on the disruptive effects of texting on simulated driving behavior. While 'driving' the simulator, subjects were engaged in a series of brief text conversations with a member of the research team. The primary dependent variable was the occurrence of Lane Excursions (defined as any time the center of the vehicle moved outside the directed driving lane, e.g., into the lane for oncoming traffic or onto the shoulder of the road), measured as (1) the percent of subjects that exhibited Lane Excursions, (2) the number of Lane Excursions occurring and (3) the percent of the texting time in Lane Excursions. Multiple Regression analyses were used to assess the influence of several factors on driving performance while texting, including text task duration, texting skill level (subject-reported), texting history (#texts/week), driver gender and driver age. Lane Excursions were not observed in the absence of texting, but 66% of subjects overall exhibited Lane Excursions while texting. Multiple Regression analysis for all subjects (N=50) revealed that text task duration was significantly correlated with the number of Lane Excursions, and texting skill level and driver age were significantly correlated with the percent of subjects exhibiting Lane Excursions. Driver gender was not significantly correlated with Lane Excursions during texting. Multiple Regression analysis of only highly skilled texters (N=27) revealed that driver age was significantly correlated with the number of Lane Excursions, the percent of subjects exhibiting Lane Excursions and the percent of texting time in Lane Excursions. In contrast, Multiple Regression analysis of those drivers who self-identified as not highly skilled texters (N=23) revealed that text task duration was significantly correlated with the number of Lane Excursions. The present studies confirm past reports that texting impairs driving simulator performance. Moreover, the present study demonstrates that for highly skilled texters, the effects of texting on driving are actually worse for older drivers. Given the increasing frequency of texting while driving within virtually all age groups, these data suggest that 'no texting while driving' education and public service messages need to be continued, and they should be expanded to target older drivers as well. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Autonomous excursions using tablets and smartphones

    NASA Astrophysics Data System (ADS)

    Marra, Wouter; Groothengel, Marin; van de Grint, Liesbeth; Karssenberg, Derek; Stouthamer, Esther

    2017-04-01

    Excursions and fieldworks are valuable components for geosciences education. However, field activities can be time consuming for teachers and pose a logistical challenge to fit in regular courses. Furthermore, the participation of students diminishes with group size in case of instructor-led outings. We are developing excursions that students can follow autonomously without a teacher present, using instructions, assignments and background information on tablets and smartphones. The goal of this approach is to increase the level of active participation, and to reduce logistical and time table issues. We developed a bike-excursion about the landscape and geology in the vicinity of our University. Such excursion was on the wish-list for several years, but posed a logistical challenge for the group of about 80 students in the available timeslot. In our approach, students had a time-window of two weeks in which they could finish the excursion in groups of 2. 8-Inch tablets with water- and shock-proof cases were available for this excursion. For the excursion we used three apps: 1) IZI-Travel for providing the route, spoken navigation instructions, spoken explanations at stops, location-related images, assignments as text, and multiple-choose questions. 2) PDF-Maps for providing geo-referenced maps. 3) ESRI Collector which the students used to digitize polygons on a map, and to collect geo-referenced photos with explanation. These data were answers to assignments and were later used in a tutorial on campus. The assignments where students had to collect data, and the small group size (pairs) increased the level of active participation. The use of a final tutorial on campus was important for the autonomous excursion, as it gave students the opportunity to discuss their observations and questions with their teacher. The developed teaching materials are available online to use and adapt for others. Parts could be useful for other universities and schools in the vicinity of the excursion location.

  8. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 1 2014-10-01 2014-10-01 false Ferries, excursion boats and other vessels. [Reserved] 38.177 Section 38.177 Transportation Office of the Secretary of Transportation AMERICANS WITH....177 Ferries, excursion boats and other vessels. [Reserved] ...

  9. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Ferries, excursion boats and other vessels. [Reserved] 38.177 Section 38.177 Transportation Office of the Secretary of Transportation AMERICANS WITH....177 Ferries, excursion boats and other vessels. [Reserved] ...

  10. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Ferries, excursion boats and other vessels. [Reserved] 38.177 Section 38.177 Transportation Office of the Secretary of Transportation AMERICANS WITH....177 Ferries, excursion boats and other vessels. [Reserved] ...

  11. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Ferries, excursion boats and other vessels. [Reserved] 38.177 Section 38.177 Transportation Office of the Secretary of Transportation AMERICANS WITH....177 Ferries, excursion boats and other vessels. [Reserved] ...

  12. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Ferries, excursion boats and other vessels. [Reserved] 38.177 Section 38.177 Transportation Office of the Secretary of Transportation AMERICANS WITH....177 Ferries, excursion boats and other vessels. [Reserved] ...

  13. Comparison of longitudinal excursion of a nerve-phantom model using quantitative ultrasound imaging and motion analysis system methods: A convergent validity study.

    PubMed

    Paquette, Philippe; El Khamlichi, Youssef; Lamontagne, Martin; Higgins, Johanne; Gagnon, Dany H

    2017-08-01

    Quantitative ultrasound imaging is gaining popularity in research and clinical settings to measure the neuromechanical properties of the peripheral nerves such as their capability to glide in response to body segment movement. Increasing evidence suggests that impaired median nerve longitudinal excursion is associated with carpal tunnel syndrome. To date, psychometric properties of longitudinal nerve excursion measurements using quantitative ultrasound imaging have not been extensively investigated. This study investigates the convergent validity of the longitudinal nerve excursion by comparing measures obtained using quantitative ultrasound imaging with those determined with a motion analysis system. A 38-cm long rigid nerve-phantom model was used to assess the longitudinal excursion in a laboratory environment. The nerve-phantom model, immersed in a 20-cm deep container filled with a gelatin-based solution, was moved 20 times using a linear forward and backward motion. Three light-emitting diodes were used to record nerve-phantom excursion with a motion analysis system, while a 5-cm linear transducer allowed simultaneous recording via ultrasound imaging. Both measurement techniques yielded excellent association ( r  = 0.99) and agreement (mean absolute difference between methods = 0.85 mm; mean relative difference between methods = 7.48 %). Small discrepancies were largely found when larger excursions (i.e. > 10 mm) were performed, revealing slight underestimation of the excursion by the ultrasound imaging analysis software. Quantitative ultrasound imaging is an accurate method to assess the longitudinal excursion of an in vitro nerve-phantom model and appears relevant for future research protocols investigating the neuromechanical properties of the peripheral nerves.

  14. Dynamics of the earth magnetic field in the 10-75 kyr period comprising the Laschamp and Mono Lake excursions: New results from the French Chaîne des Puys in a global perspective

    NASA Astrophysics Data System (ADS)

    Laj, Carlo; Guillou, Hervé; Kissel, Catherine

    2014-02-01

    We report here on a new paleomagnetic (directions and intensities) and coupled K/Ar and 40Ar/39Ar analysis of 35 different flows, emplaced in the Chaîne des Puys during the 75 to 10 kyr interval, which contains the Mono Lake and Laschamp excursions. There is a remarkable agreement between the new set of absolute volcanic intensities and published sedimentary (GLOPIS-75) and cosmogenic (10Be and 36Cl) records. The Laschamp and Mono Lake excursions are clearly revealed by a very significant intensity drop at 41.2±1.6 ka and 34.2±1.2 ka respectively. The duration of the Laschamp excursion is ˜1500 yr and about 640 yr when the drop of paleointensity or the directional change are considered respectively. The intensity drop at the Mono Lake is twice as short. In the ˜7 ka interval separating the two excursions, the field intensity recovers to almost non-transitional values. The rate of decrease of the field intensity during these excursions attains 18 nT/yr for the Laschamp and even greater value (33 nT/yr) for the Mono Lake. This figure is, for the Laschamp excursion, similar to the present field intensity decrease in the last two centuries so that one may wonder whether such a high rate of change may be characteristic of an impending geomagnetic event (reversal or excursion). We suggest that the name Auckland excursion should be used for the present-day called Mono Lake.

  15. Condylar motion in children with primary dentition during lateral excursion.

    PubMed

    Yamasaki, Youichi; Hayasaki, Haruaki; Nishi, Megumi; Nakata, Shiho; Nakata, Minoru

    2002-07-01

    Normal development of primary and mixed dentition is indispensable for establishing a healthy mandibular function of the permanent dentition. Because condylar movements are crucial for mandibular function, extensive studies have been reported. However, most of these studies have dealt with mandibular functions in adults, and there is less known about children with primary dentition. The purpose of this study was to clarify the condylar movements during lateral excursions in children with primary dentition and compare these movements with those of adults from the viewpoint of functional development. With use of an optoelectronic recording system with six degrees of freedom, the lateral excursions of 24 children and 20 young women, with sound dentition, were recorded at 100 Hz. The results show that the balancing side condyle of the children had a significantly smaller vertical excursion and a significantly larger anteroposterior excursion than that of adults, indicating the shallower and more anteriorly directed movements of the entire mandible during lateral excursions in children with primary dentition.

  16. Excursions out-of-lane versus standard deviation of lateral position as outcome measure of the on-the-road driving test.

    PubMed

    Verster, Joris C; Roth, Thomas

    2014-07-01

    The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. A literature search was conducted to search for driving tests that used both SDLP and excursions out-of-lane as outcome measures. The analyses were limited to studies examining hypnotic drugs because several of these drugs have been shown to produce next-morning sedation. Standard deviation of lateral position was more sensitive in demonstrating driving impairment. In fact, solely relying on excursions out-of-lane as outcome measure incorrectly classifies approximately half of impaired drives as unimpaired. The frequency of excursions out-of-lane is determined by the mean lateral position within the right traffic lane. Defining driving impairment as having a ΔSDLP > 2.4 cm, half of the impaired driving tests (51.2%, 43/84) failed to produce excursions out-of-lane. Alternatively, 20.9% of driving tests with ΔSDLP < 2.4 cm (27/129) had at least one excursion out-of-lane. Excursions out-of-lane are neither a suitable measure to demonstrate driving impairment nor is this measure sufficiently sensitive to differentiate adequately between differences in magnitude of driving impairment. Copyright © 2014 John Wiley & Sons, Ltd.

  17. Altered lower extremity joint mechanics occur during the star excursion balance test and single leg hop after ACL-reconstruction in a collegiate athlete.

    PubMed

    Samaan, Michael A; Ringleb, Stacie I; Bawab, Sebastian Y; Greska, Eric K; Weinhandl, Joshua T

    2018-03-01

    The effects of ACL-reconstruction on lower extremity joint mechanics during performance of the Star Excursion Balance Test (SEBT) and Single Leg Hop (SLH) are limited. The purpose of this study was to determine if altered lower extremity mechanics occur during the SEBT and SLH after ACL-reconstruction. One female Division I collegiate athlete performed the SEBT and SLH tasks, bilaterally, both before ACL injury and 27 months after ACL-reconstruction. Maximal reach, hop distances, lower extremity joint kinematics and moments were compared between both time points. Musculoskeletal simulations were used to assess muscle force production during the SEBT and SLH at both time points. Compared to the pre-injury time point, SEBT reach distances were similar in both limbs after ACL-reconstruction except for the max anterior reach distance in the ipsilateral limb. The athlete demonstrated similar hop distances, bilaterally, after ACL-reconstruction compared to the pre-injury time point. Despite normal functional performance during the SEBT and SLH, the athlete exhibited altered lower extremity joint mechanics during both of these tasks. These results suggest that measuring the maximal reach and hop distances for these tasks, in combination with an analysis of the lower extremity joint mechanics that occur after ACL-reconstruction, may help clinicians and researchers to better understand the effects of ACL-reconstruction on the neuromuscular system during the SEBT and SLH.

  18. Comparative in vivo forefoot kinematics of Homo sapiens and Pan paniscus.

    PubMed

    Griffin, Nicole L; D'Août, Kristiaan; Richmond, Brian; Gordon, Adam; Aerts, Peter

    2010-12-01

    The human metatarsophalangeal joints play a key role in weight transmission and propulsion during bipedal gait, but at present, the identification of when a habitual, human-like metatarsi-fulcrimating mechanism first appeared in the fossil record is debated. Part of this debate can be attributed to the absence of certain detailed quantitative data distinguishing human and great ape forefoot form and function. The aim of this study is to quantitatively test previous observations that human metatarsophalangeal joints exhibit greater amounts of dorsal excursion (i.e., dorsiflexion) than those of Pan at the terminal stance phase of terrestrial locomotion. Video recordings were made in order to measure sagittal excursions of the medial metatarsophalangeal joints in habitually shod/unshod adult humans and adult bonobos (Pan paniscus). Results indicate that the human first and second metatarsophalangeal joints usually dorsiflex more than those of bonobos. When timing of maximum excursion of the first metatarsophalangeal joint is coupled with existing plantar pressure data, the unique role of the human forefoot as a key site of leverage and weight transmission is highlighted. These results support hypotheses that significant joint functional differences between great apes and humans during gait underlie taxonomic distinctions in trabecular bone architecture of the forefoot. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. Evolution and Adaptation of Phytoplankton Photosynthetic Pathways to perturbations of the geological carbon system

    NASA Astrophysics Data System (ADS)

    Rickaby, R. E.; Young, J. N.; Hermoso, M.; Heureux, A.; McCLelland, H.; Lee, R.; Eason Hubbard, M.

    2012-12-01

    The ocean and atmosphere carbon system has varied greatly over geological history both in response to initial evolutionary innovation, and as a driver of adaptive change. Here we establish that positive selection in Rubisco, the most abundant enzyme on the Earth responsible for all photosynthetic carbon fixation, occurred early in Earth's history, and basal to the radiation of the modern marine algal groups. Our signals of positive selection appear to be triggered by changing intracellular concentrations of carbon dioxide (CO2) due to the emergence of carbon concentrating mechanisms between 1.56 and 0.41 Ba in response to declining atmospheric CO2 . We contend that, at least in terms of carbon, phytoplankton generally were well poised to manage subsequent abrupt carbon cycle perturbations. The physiological pathways for optimising carbon acquisition across a wide range of ambient carbon dioxide concentrations had already been established and were genetically widespread across open ocean phytoplankton groups. We will further investigate some case studies from the Mesozoic and Cenozoic abrupt carbon cycle excursions using isotopic tools to probe the community photosynthetic response and demonstrate the flexibility of phytoplankton photosynthesis in the face of major perturbations. In particular, an unprecedented resolution record across the Toarcian (Early Jurassic) carbon isotope excursion in the Paris Basin reveals a selection and evolution towards a community reliant solely on diffusive carbon dioxide supply for photosynthesis at the height of the excursion at 1500-2500 ppm CO2. The continued flourishing of the phytoplankton biological pump throughout this excursion was able to remove the excess carbon injected into the water column in less than 45 kyrs.

  20. Relative fascicle excursion effects on dynamic strength generation during gait in children with cerebral palsy.

    PubMed

    Martín Lorenzo, T; Lerma Lara, S; Martínez-Caballero, I; Rocon, E

    2015-10-01

    Evaluation of muscle structure gives us a better understanding of how muscles contribute to force generation which is significantly altered in children with cerebral palsy (CP). While most muscle structure parameters have shown to be significantly correlated to different expressions of strength development in children with CP and typically developing (TD) children, conflicting results are found for muscle fascicle length. Muscle fascicle length determines muscle excursion and velocity, and contrary to what might be expected, correlations of fascicle length to rate of force development have not been found for children with CP. The lack of correlation between muscle fascicle length and rate of force development in children with CP could be due, on the one hand, to the non-optimal joint position adopted for force generation on the isometric strength tests as compared to the position of TD children. On the other hand, the lack of correlation could be due to the erroneous assumption that muscle fascicle length is representative of sarcomere length. Thus, the relationship between muscle architecture parameters reflecting sarcomere length, such as relative fascicle excursions and dynamic power generation, should be assessed. Understanding of the underlying mechanisms of weakness in children with CP is key for individualized prescription and assessment of muscle-targeted interventions. Findings could imply the detection of children operating on the descending limb of the sarcomere length-tension curve, which in turn might be at greater risk of developing crouch gait. Furthermore, relative muscle fascicle excursions could be used as a predictive variable of outcomes related to crouch gait prevention treatments such as strength training. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. 46 CFR 2.01-45 - Excursion permit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., on Coast Guard Form CG-950, Application for Excursion Permit. If, after inspection, permission is... the application process for excursion permits for inspected passenger vessels are contained in §§ 71.10, 115.204, or 176.204 of this chapter. Details concerning the application process for special...

  2. Effects of medially wedged foot orthoses on knee and hip joint running mechanics in females with and without patellofemoral pain syndrome.

    PubMed

    Boldt, Andrew R; Willson, John D; Barrios, Joaquin A; Kernozek, Thomas W

    2013-02-01

    We examined the effects of medially wedged foot orthoses on knee and hip joint mechanics during running in females with and without patellofemoral pain syndrome (PFPS). We also tested if these effects depend on standing calcaneal eversion angle. Twenty female runners with and without PFPS participated. Knee and hip joint transverse and frontal plane peak angle, excursion, and peak internal knee and hip abduction moment were calculated while running with and without a 6° full-length medially wedged foot orthoses. Separate 3-factor mixed ANOVAs (group [PFPS, control] x condition [medial wedge, no medial wedge] x standing calcaneal angle [everted, neutral, inverted]) were used to test the effect of medially wedged orthoses on each dependent variable. Knee abduction moment increased 3% (P = .03) and hip adduction excursion decreased 0.6° (P < .01) using medially wedged foot orthoses. No significant group x condition or calcaneal angle x condition effects were observed. The addition of medially wedged foot orthoses to standardized running shoes had minimal effect on knee and hip joint mechanics during running thought to be associated with the etiology or exacerbation of PFPS symptoms. These effects did not appear to depend on injury status or standing calcaneal posture.

  3. 46 CFR 115.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... jacket, fire safety, and manning standards applicable to a vessel in the service for which the excursion... crew required, any additional lifesaving or safety equipment required, the route for which the permit... applicable minimum safety standards when issuing an excursion permit. In particular, a vessel that is being...

  4. 46 CFR 115.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... jacket, fire safety, and manning standards applicable to a vessel in the service for which the excursion... crew required, any additional lifesaving or safety equipment required, the route for which the permit... applicable minimum safety standards when issuing an excursion permit. In particular, a vessel that is being...

  5. 46 CFR 115.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... jacket, fire safety, and manning standards applicable to a vessel in the service for which the excursion... crew required, any additional lifesaving or safety equipment required, the route for which the permit... applicable minimum safety standards when issuing an excursion permit. In particular, a vessel that is being...

  6. 40 CFR 63.1438 - Parameter monitoring levels and excursions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required to submit Periodic Reports semiannually or quarterly. The first semiannual period is the 6-month... excursions. (5) For the fifth semiannual period—two excused excursions. (6) For the sixth and all subsequent... during the entire test period. The monitoring level(s) shall be those established during from the...

  7. 40 CFR 63.1438 - Parameter monitoring levels and excursions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required to submit Periodic Reports semiannually or quarterly. The first semiannual period is the 6-month... excursions. (5) For the fifth semiannual period—two excused excursions. (6) For the sixth and all subsequent... during the entire test period. The monitoring level(s) shall be those established during from the...

  8. 40 CFR 63.1438 - Parameter monitoring levels and excursions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required to submit Periodic Reports semiannually or quarterly. The first semiannual period is the 6-month... excursions. (5) For the fifth semiannual period—two excused excursions. (6) For the sixth and all subsequent... during the entire test period. The monitoring level(s) shall be those established during from the...

  9. 40 CFR 63.1438 - Parameter monitoring levels and excursions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required to submit Periodic Reports semiannually or quarterly. The first semiannual period is the 6-month... excursions. (5) For the fifth semiannual period—two excused excursions. (6) For the sixth and all subsequent... during the entire test period. The monitoring level(s) shall be those established during from the...

  10. 36 CFR 1192.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Ferries, excursion boats and other vessels. [Reserved] 1192.177 Section 1192.177 Parks, Forests, and Public Property ARCHITECTURAL... GUIDELINES FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 1192.177 Ferries, excursion boats and...

  11. 36 CFR 1192.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Ferries, excursion boats and other vessels. [Reserved] 1192.177 Section 1192.177 Parks, Forests, and Public Property ARCHITECTURAL... GUIDELINES FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 1192.177 Ferries, excursion boats and...

  12. 36 CFR 1192.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Ferries, excursion boats and other vessels. [Reserved] 1192.177 Section 1192.177 Parks, Forests, and Public Property ARCHITECTURAL... GUIDELINES FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 1192.177 Ferries, excursion boats and...

  13. 36 CFR 1192.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Ferries, excursion boats and other vessels. [Reserved] 1192.177 Section 1192.177 Parks, Forests, and Public Property ARCHITECTURAL... GUIDELINES FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 1192.177 Ferries, excursion boats and...

  14. Free gracilis transfer for smile in children: the Massachusetts Eye and Ear Infirmary Experience in excursion and quality-of-life changes.

    PubMed

    Hadlock, Tessa A; Malo, Juan S; Cheney, Mack L; Henstrom, Douglas K

    2011-01-01

    Free muscle transfer for facial reanimation has become the standard of care in recent decades and is now the cornerstone intervention for dynamic smile reanimation. We sought to quantify smile excursion and quality-of-life (QOL) changes in our pediatric free gracilis recipients following reanimation. We quantified gracilis muscle excursion in 17 pediatric patients undergoing 19 consecutive pediatric free gracilis transplantation operations, using our validated SMILE program, as an objective measure of functional outcome. These were compared against excursion measured the same way in a cohort of 17 adults with 19 free gracilis operations. In addition, we prospectively evaluated QOL outcomes in these children using the Facial Clinimetric Evaluation (FaCE) instrument. The mean gracilis excursion in our pediatric free gracilis recipients was 8.8 mm ± 5.0 mm, which matched adult results, but with fewer complete failures of less than 2-mm excursion, with 2 (11%) and 4 (21%), respectively. Quality-of-life measures indicated statistically significant improvements following dynamic smile reanimation (P = .01). Dynamic facial reanimation using free gracilis transfer in children has an acceptable success rate, yields improved commissure excursion, and improves QOL in the pediatric population. It should be considered first-line therapy for children with lack of a meaningful smile secondary to facial paralysis.

  15. The Blake geomagnetic excursion recorded in a radiometrically dated speleothem

    NASA Astrophysics Data System (ADS)

    Osete, María-Luisa; Martín-Chivelet, Javier; Rossi, Carlos; Edwards, R. Lawrence; Egli, Ramon; Muñoz-García, M. Belén; Wang, Xianfeng; Pavón-Carrasco, F. Javier; Heller, Friedrich

    2012-11-01

    One of the most important developments in geomagnetism has been the recognition of polarity excursions of the Earth's magnetic field. Accurate timing of the excursions is a key point for understanding the geodynamo process and for magnetostratigraphic correlation. One of the best-known excursions is the Blake geomagnetic episode, which occurred during marine isotope stage MIS 5, but its morphology and age remain controversial. Here we show, for the first time, the Blake excursion recorded in a stalagmite which was dated using the uranium-series disequilibrium techniques. The characteristic remanent magnetisation is carried by fine-grained magnetite. The event is documented by two reversed intervals (B1 and B2). The age of the event is estimated to be between 116.5±0.7 kyr BP and 112.0±1.9 kyr BP, slightly younger (∼3-4 kyr) than recent estimations from sedimentary records dated by astronomical tuning. Low values of relative palaeointensity during the Blake episode are estimated, but a relative maximum in the palaeofield intensity coeval with the complete reversal during the B2 interval was observed. Duration of the Blake geomagnetic excursion is 4.5 kyr, two times lower than single excursions and slightly higher than the estimated diffusion time for the inner core (∼3 kyr).

  16. An Evaluation of the British Columbia Asthma Monitoring System (BCAMS) and PM2.5 Exposure Metrics during the 2014 Forest Fire Season

    PubMed Central

    McLean, Kathleen E.; Yao, Jiayun; Henderson, Sarah B.

    2015-01-01

    The British Columbia Asthma Monitoring System (BCAMS) tracks forest fire smoke exposure and asthma-related health outcomes, identifying excursions beyond expected daily counts. Weekly reports during the wildfire season support public health and emergency management decision-making. We evaluated BCAMS by identifying excursions for asthma-related physician visits and dispensations of the reliever medication salbutamol sulfate and examining their corresponding smoke exposures. A disease outbreak detection algorithm identified excursions from 1 July to 31 August 2014. Measured, modeled, and forecasted concentrations of fine particulate matter (PM2.5) were used to assess exposure. We assigned PM2.5 levels to excursions by choosing the highest value within a seven day window centred on the excursion day. Smoky days were defined as those with PM2.5 levels ≥ 25 µg/m3. Most excursions (57%–71%) were assigned measured or modeled PM2.5 concentrations of 10 µg/m3 or higher. Of the smoky days, 55.8% and 69.8% were associated with at least one excursion for physician visits and salbutamol dispensations, respectively. BCAMS alerted most often when measures of smoke exposure were relatively high. Better performance might be realized by combining asthma-related outcome metrics in a bivariate model. PMID:26075727

  17. Atmospheric Carbon Dioxide and its Relation to Carbon Cycle Perturbations During Ocean Anoxic Event 1d: A High Resolution Record From Dispersed Plant Cuticle

    NASA Astrophysics Data System (ADS)

    Richey, J. D.; Upchurch, G. R.; Joeckel, R.; Smith, J. J.; Ludvigson, G. A.; Lomax, B. H.

    2013-12-01

    Past geological greenhouse intervals are associated with Ocean Anoxic Events (OAEs), which result from an increase in marine primary productivity and/or an increase in the preservation of organic matter. The end point is widespread black shale deposition combined with a long-term atmospheric positive δ13C excursion and an increase in the burial of 12C. Some OAEs show a negative δ13C excursion preceding the positive excursion, indicating a perturbation in the global carbon cycle prior to the initiation of these events. The Rose Creek (RCP) locality, southeastern Nebraska, is the only known terrestrial section that preserves OAE1d (Cretaceous, Albian-Cenomanian Boundary) and has abundant charcoal and plant cuticle. These features allow for a combined carbon isotope and stomatal index (SI) analysis to determine both changes in the cycling between carbon pools (C isotope analysis) and changes in paleo-CO2 via changes in SI. Preliminary (and ongoing) SI data analysis using dispersed cuticle of Pandemophyllum kvacekii (an extinct Laurel) collected at 30 cm intervals indicate changes in SI consistent with changes in CO2. Fitting our samples to a published RCP δ13C profile, pre-excursion CO2 concentrations are high. CO2 decreases to lower concentrations in the basal 1.2 m of the RCP section, where δ13Cbulk shows a negative excursion and δ13Ccharcoal remains at pre-excursion values. CO2 concentrations become higher toward the top of the negative δ13C excursion, where δ13Cbulk and δ13Ccharcoal are at their most negative values, and drop as the negative carbon excursion terminates. Using published transfer functions, we estimate that pre-excursion CO2 concentrations were a maximum of 900 ppm. In the basal 1.2 m of RCP, CO2 drops to a maximum of 480 ppm, and rises to a maximum of 710 ppm near the top of the negative excursion. As δ13C values rise towards pre-excursion values, CO2 declines to a maximum of 400 ppm. The trend in SI is comparable to the trend in δ13Ccharcoal and follows recognized patterns, while SI shows partial divergence from δ13Cbulk. These data, while preliminary, highlight the importance of considering isotope substrate when investigating carbon cycle perturbations.

  18. Validation of color Doppler sonography for evaluating relative displacement between the flexor tendon and subsynovial connective tissue.

    PubMed

    Tat, Jimmy; Kociolek, Aaron M; Keir, Peter J

    2015-04-01

    A common pathologic finding in carpal tunnel syndrome is fibrosis and thickening of the subsynovial connective tissue. This finding suggests an etiology of excessive shear forces, with relative longitudinal displacement between the flexor tendon and adjacent subsynovial connective tissue. The purpose of this study was to validate color Doppler sonography for measurement of tendon displacement over time. Eight unmatched fresh frozen cadaver arms were used to evaluate color Doppler sonography for measurement of tendon displacement. The middle flexor digitorum superficialis tendon was moved through a physiologic excursion of 20 mm at 3 different tendon velocities (50, 100, and 150 mm/s). We found that color Doppler sonography provided accurate measurement of tendon displacement, with absolute errors of -0.05 mm (50 mm/s), -1.24 mm (100 mm/s), and -2.36 mm (150 mm/s) on average throughout the tendon excursion range. Evaluating relative displacement between the tendon and subsynovial connective tissue during finger flexion-extension movements also offered insight into the gliding mechanism of the subsynovial connective tissue. During flexion, we observed a curvilinear increase in relative displacement, with greater differential motion at the end range of displacement, likely due to the sequential stretch of the fibrils between successive layers of the subsynovial connective tissue. In extension, there was a linear return in relative displacement, suggesting a different unloading mechanism characterized by uniform relaxation of fibrils. We demonstrated the validity of color Doppler displacement for use in the evaluation of relative motion. Color Doppler sonography is useful in our understanding of the behavior of the subsynovial connective tissue during tendon excursion, which may elucidate the role of finger motion in the etiology of shear injury. © 2015 by the American Institute of Ultrasound in Medicine.

  19. Proceedings of the Army Symposium on Solid Mechanics, 1982 - Critical Mechanics Problems in Systems Design, 21-23 September 1982, Bass River, Cape Cod, Massachusetts

    DTIC Science & Technology

    1982-09-01

    INTRODUCTION In the design of lightly armored vehicles it is of critical importance to be able to predict the vulnerability of these systems to...to similar geometry steel projectiles tested previously. INTRODUCTION The use of magnesium in proposed warhead designs has prompted renewed...to examine these excursions. INTRODUCTION The survival of a deeply buried missile capsule in a sand shaft was being evaluated during the

  20. 46 CFR 72.25-15 - Passenger accommodations for excursion boats, ferryboats, and passenger barges.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 3 2012-10-01 2012-10-01 false Passenger accommodations for excursion boats, ferryboats, and passenger barges. 72.25-15 Section 72.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... accommodations for excursion boats, ferryboats, and passenger barges. (a) Except as specifically excluded by this...

  1. 36 CFR § 1192.177 - Ferries, excursion boats and other vessels. [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Ferries, excursion boats and other vessels. [Reserved] § 1192.177 Section § 1192.177 Parks, Forests, and Public Property... GUIDELINES FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 1192.177 Ferries, excursion boats and...

  2. 46 CFR 72.25-15 - Passenger accommodations for excursion boats, ferryboats, and passenger barges.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 3 2013-10-01 2013-10-01 false Passenger accommodations for excursion boats, ferryboats, and passenger barges. 72.25-15 Section 72.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... accommodations for excursion boats, ferryboats, and passenger barges. (a) Except as specifically excluded by this...

  3. 46 CFR 72.25-15 - Passenger accommodations for excursion boats, ferryboats, and passenger barges.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Passenger accommodations for excursion boats, ferryboats, and passenger barges. 72.25-15 Section 72.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... accommodations for excursion boats, ferryboats, and passenger barges. (a) Except as specifically excluded by this...

  4. 46 CFR 72.25-15 - Passenger accommodations for excursion boats, ferryboats, and passenger barges.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 3 2014-10-01 2014-10-01 false Passenger accommodations for excursion boats, ferryboats, and passenger barges. 72.25-15 Section 72.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... accommodations for excursion boats, ferryboats, and passenger barges. (a) Except as specifically excluded by this...

  5. 46 CFR 72.25-15 - Passenger accommodations for excursion boats, ferryboats, and passenger barges.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 3 2011-10-01 2011-10-01 false Passenger accommodations for excursion boats, ferryboats, and passenger barges. 72.25-15 Section 72.25-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... accommodations for excursion boats, ferryboats, and passenger barges. (a) Except as specifically excluded by this...

  6. Cruising through Research: Library Skills for Young Adults.

    ERIC Educational Resources Information Center

    Volkman, John D.

    This book presents an approach for school librarians to use to introduce basic research tools to students in grades 7-12. Twelve "Excursions" (i.e., library research projects) are described. Excursions 1 and 2 provide an introduction to reference books, and Excursions 3 and 4 explore note-taking and basic organization of research papers. The…

  7. Sedimentary and Volcanic Records of the Laschamp and Mono Lake Excursions from Australia and New Zealand

    NASA Astrophysics Data System (ADS)

    Ingham, E. M.; Roberts, A. P.; Turner, G. M.; Heslop, D.; Ronge, T.; Conway, C.; Leonard, G.; Townsend, D.; Tiedemann, R.; Lamy, F.; Calvert, A. T.

    2014-12-01

    Geomagnetic excursions are short-lived deviations of the geomagnetic field from the normal range of secular variation. Despite significant advances in geomagnetic excursion research over the past 20 years, fundamental questions remain concerning the typical duration and global morphology of excursional geomagnetic fields. To answer such questions, more high-resolution, chronologically well-constrained excursion records are required, particularly from the Southern Hemisphere. We present preliminary paleomagnetic records of the Laschamp (~41 ka) and Mono Lake (~35 ka) excursions from three marine sediment cores from the Bounty Trough, New Zealand margin, and complementary volcanic records of the Laschamp excursion from lavas of Mt Ruapehu, New Zealand. Relatively high sedimentation rates of 12 - 26 cm/kyr in the Bounty Trough during glacial periods allow identification of excursional field behavior at each of the studied core locations. Each core displays one or two excursional events, with rapid directional swings between stable normal polarity and reversed excursional directions, each associated with coincident relative paleointensity minima. These anomalous paleomagnetic directions are interpreted to represent the Laschamp and Mono Lake excursions, based on a combination of tephrochronology, radiocarbon dating, and cyclostratigraphy (defined from core-scanning X-ray fluorescence and magnetic susceptibility records). Beside these records, we present results from fourteen lava flows, on Mt Ruapehu, for which 40Ar-39Ar dating indicates ages of between 39 and 45 ka. The step heating 40Ar-39Ar experiments produced particularly flat age plateaus, with corresponding 2 s.d. errors mostly approaching 1 kyr. The youngest and oldest flows carry normal polarity magnetization, however six flows, dated between 41 and 43 ka, display transitional field characteristics. Three of these flows display a declination swing of around 180o, which coincides with a previously published result from the Auckland Basalt Field. Together, these data provide rare excursion records from the southern hemisphere, which will provide an improved view of geomagnetic field morphology during these excursions.

  8. Observational constraints on monomial warm inflation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Visinelli, Luca, E-mail: Luca.Visinelli@studio.unibo.it

    Warm inflation is, as of today, one of the best motivated mechanisms for explaining an early inflationary period. In this paper, we derive and analyze the current bounds on warm inflation with a monomial potential U ∝ φ {sup p} , using the constraints from the PLANCK mission. In particular, we discuss the parameter space of the tensor-to-scalar ratio r and the potential coupling λ of the monomial warm inflation in terms of the number of e-folds. We obtain that the theoretical tensor-to-scalar ratio r ∼ 10{sup −8} is much smaller than the current observational constrain r ∼< 0.12, despitemore » a relatively large value of the field excursion Δ φ ∼ 0.1 M {sub Pl}. Warm inflation thus eludes the Lyth bound set on the tensor-to-scalar ratio by the field excursion.« less

  9. ODP Site 1063 (Bermuda Rise) revisited: Oxygen isotopes, excursions and paleointensity in the Brunhes Chron

    NASA Astrophysics Data System (ADS)

    Channell, J. E. T.; Hodell, D. A.; Curtis, J. H.

    2012-02-01

    An age model for the Brunhes Chron of Ocean Drilling Program (ODP) Site 1063 (Bermuda Rise) is constructed by tandem correlation of oxygen isotope and relative paleointensity data to calibrated reference templates. Four intervals in the Brunhes Chron where paleomagnetic inclinations are negative for both u-channel samples and discrete samples are correlated to the following magnetic excursions with Site 1063 ages in brackets: Laschamp (41 ka), Blake (116 ka), Iceland Basin (190 ka), Pringle Falls (239 ka). These ages are consistent with current age estimates for three of these excursions, but not for "Pringle Falls" which has an apparent age older than a recently published estimate by ˜28 kyr. For each of these excursions (termed Category 1 excursions), virtual geomagnetic poles (VGPs) reach high southerly latitudes implying paired polarity reversals of the Earth's main dipole field, that apparently occurred in a brief time span (<2 kyr in each case), several times shorter than the apparent duration of regular polarity transitions. In addition, several intervals of low paleomagnetic inclination (low and negative in one case) are observed both in u-channel and discrete samples at ˜318 ka (MIS 9), ˜412 ka (MIS 11) and in the 500-600 ka interval (MIS 14-15). These "Category 2" excursions may constitute inadequately recorded (Category 1) excursions, or high amplitude secular variation.

  10. Design, Analysis, and On-Sun Evaluation of Reflective Strips Under Controlled Buckling

    NASA Technical Reports Server (NTRS)

    Jaworske, Donald A.; Sechkar, Edward A.; Colozza, Anthony J.

    2014-01-01

    Solar concentrators are envisioned for use in a variety of space-based applications, including applications involving in situ resource utilization. Identifying solar concentrators that minimize mass and cost are of great interest, especially since launch cost is driven in part by the mass of the payload. Concentrators must also be able to survive the wide temperature excursions on the lunar surface. Identifying smart structures which compensate for changes in concentrator geometry brought about by temperature extremes are of interest. Some applications may benefit from the ability to change the concentrators focal pattern at will. This paper addresses a method of designing a single reflective strip to produce a desired focal pattern through the use of controlled buckling. Small variations in the cross section over the length of the reflective strip influence the distribution of light in the focal region. A finite element method of analysis is utilized here which calculates the curve produced for a given strip cross section and axial load. Varying axial force and strip cross section over the length of the reflective strip provide a means of optimizing ray convergence in the focal region. Careful selection of a tapered cross section yields a reflective strip that approximates a parabola. An array of reflective strips under controlled buckling produces a light weight concentrator and adjustments in the compression of individual strips provide a means of compensating for temperature excursions or changing the focal pattern at will.

  11. Design, Analysis, and On-Sun Evaluation of Reflective Strips Under Controlled Buckling

    NASA Technical Reports Server (NTRS)

    Jaworske, D. A.; Sechkar, E. A.; Colozza, A. J.

    2014-01-01

    Solar concentrators are envisioned for use in a variety of space-based applications, including applications involving in situ resource utilization. Identifying solar concentrators that minimize mass and cost are of great interest, especially since launch cost is driven in part by the mass of the payload. Concentrators must also be able to survive the wide temperature excursions on the lunar surface. Identifying smart structures which compensate for changes in concentrator geometry brought about by temperature extremes are of interest. Some applications may benefit from the ability to change the concentrator's focal pattern at will. This paper addresses a method of designing a single reflective strip to produce a desired focal pattern through the use of controlled buckling. Small variations in the cross section over the length of the reflective strip influence the distribution of light in the focal region. A finite element method of analysis is utilized here which calculates the curve produced for a given strip cross section and axial load. Varying axial force and strip cross section over the length of the reflective strip provide a means of optimizing ray convergence in the focal region. Careful selection of a tapered cross section yields a reflective strip that approximates a parabola. An array of reflective strips under controlled buckling produces a light weight concentrator and adjustments in the compression of individual strips provide a means of compensating for temperature excursions or changing the focal pattern at will.

  12. Deciphering the impact of diagenesis overprint on negative δ13C excursions using rock magnetism: Case study of Ediacaran carbonates, Yangjiaping section, South China

    NASA Astrophysics Data System (ADS)

    Macouin, Mélina; Ader, Magali; Moreau, Marie-Gabrielle; Poitou, Charles; Yang, Zhenyu; Sun, Zhimming

    2012-10-01

    Rock magnetism is used here to investigate the genesis of one of the puzzling negative carbon isotopic excursions of the Neoproterozoic in the Yangtze platform (South China). A detailed characterization of the magnetic mineralogy, which includes low-temperature and high-field magnetometry and classical magnetic measurement (ARM, IRM, susceptibility), was therefore performed along upper Doushantuo and lower Dengying Formations outcropping in the Yangjiaping section. The derived magnetic parameters show variations that can be interpreted as variations in magnetic grains size and in oxide contents. They show that the magnetic content is significantly reduced in samples presenting negative δ13Ccalcite values. We interpret this as a result of magnetite dissolution and secondary carbonate precipitation during early diagenesis bacterial sulfate reduction. Combined with C and O isotopic data, paleomagnetic techniques thus show that the upper Doushantuo-lower Dengying negative excursion of the Yangjiaping section is largely due to diagenesis, although the preservation of a genuine δ13C excursion of lower magnitude from +7‰ down to 0‰, instead of down to -9‰ as usually considered, cannot be ruled out. A corrected δ13Ccarbonate chemostratigraphic curve is therefore proposed. The unambiguous identification of a strong diagenetic component for this excursion casts doubts on the primary nature of other potentially time equivalent negative excursions of the Yangtze platform and thus to its correlation to negative excursions in other cratons (i.e. Shuram excursion). More generally, this study illustrates the potential of magnetic mineralogy characterization, a low cost, time efficient and non-destructive technique, as screening tool for diagenetic overprints of δ13C and δ18O.

  13. Relaxation from particle production

    DOE PAGES

    Hook, Anson; Marques-Tavares, Gustavo

    2016-12-20

    Here, we consider using particle production as a friction force by which to implement a “Relaxion” solution to the electroweak hierarchy problem. Using this approach, we are able to avoid superplanckian field excursions and avoid any conflict with the strong CP problem. The relaxation mechanism can work before, during or after inflation allowing for inflationary dynamics to play an important role or to be completely decoupled.

  14. The Role of Arch Compression and Metatarsophalangeal Joint Dynamics in Modulating Plantar Fascia Strain in Running

    PubMed Central

    McDonald, Kirsty A.; Stearne, Sarah M.; Alderson, Jacqueline A.; North, Ian; Pires, Neville J.; Rubenson, Jonas

    2016-01-01

    Elastic energy returned from passive-elastic structures of the lower limb is fundamental in lowering the mechanical demand on muscles during running. The purpose of this study was to investigate the two length-modulating mechanisms of the plantar fascia, namely medial longitudinal arch compression and metatarsophalangeal joint (MPJ) excursion, and to determine how these mechanisms modulate strain, and thus elastic energy storage/return of the plantar fascia during running. Eighteen runners (9 forefoot and 9 rearfoot strike) performed three treadmill running trials; unrestricted shod, shod with restricted arch compression (via an orthotic-style insert), and barefoot. Three-dimensional motion capture and ground reaction force data were used to calculate lower limb kinematics and kinetics including MPJ angles, moments, powers and work. Estimates of plantar fascia strain due to arch compression and MPJ excursion were derived using a geometric model of the arch and a subject-specific musculoskeletal model of the plantar fascia, respectively. The plantar fascia exhibited a typical elastic stretch-shortening cycle with the majority of strain generated via arch compression. This strategy was similar in fore- and rear-foot strike runners. Restricting arch compression, and hence the elastic-spring function of the arch, was not compensated for by an increase in MPJ-derived strain. In the second half of stance the plantar fascia was found to transfer energy between the MPJ (energy absorption) and the arch (energy production during recoil). This previously unreported energy transfer mechanism reduces the strain required by the plantar fascia in generating useful positive mechanical work at the arch during running. PMID:27054319

  15. The Role of Arch Compression and Metatarsophalangeal Joint Dynamics in Modulating Plantar Fascia Strain in Running.

    PubMed

    McDonald, Kirsty A; Stearne, Sarah M; Alderson, Jacqueline A; North, Ian; Pires, Neville J; Rubenson, Jonas

    2016-01-01

    Elastic energy returned from passive-elastic structures of the lower limb is fundamental in lowering the mechanical demand on muscles during running. The purpose of this study was to investigate the two length-modulating mechanisms of the plantar fascia, namely medial longitudinal arch compression and metatarsophalangeal joint (MPJ) excursion, and to determine how these mechanisms modulate strain, and thus elastic energy storage/return of the plantar fascia during running. Eighteen runners (9 forefoot and 9 rearfoot strike) performed three treadmill running trials; unrestricted shod, shod with restricted arch compression (via an orthotic-style insert), and barefoot. Three-dimensional motion capture and ground reaction force data were used to calculate lower limb kinematics and kinetics including MPJ angles, moments, powers and work. Estimates of plantar fascia strain due to arch compression and MPJ excursion were derived using a geometric model of the arch and a subject-specific musculoskeletal model of the plantar fascia, respectively. The plantar fascia exhibited a typical elastic stretch-shortening cycle with the majority of strain generated via arch compression. This strategy was similar in fore- and rear-foot strike runners. Restricting arch compression, and hence the elastic-spring function of the arch, was not compensated for by an increase in MPJ-derived strain. In the second half of stance the plantar fascia was found to transfer energy between the MPJ (energy absorption) and the arch (energy production during recoil). This previously unreported energy transfer mechanism reduces the strain required by the plantar fascia in generating useful positive mechanical work at the arch during running.

  16. Use of an Anatomical Scalar to Control for Sex-Based Size Differences in Measures of Hyoid Excursion during Swallowing

    ERIC Educational Resources Information Center

    Molfenter, Sonja M.; Steele, Catriona M.

    2014-01-01

    Purpose: Traditional methods for measuring hyoid excursion from dynamic videofluoroscopy recordings involve calculating changes in position in absolute units (mm). This method shows a high degree of variability across studies but agreement that greater hyoid excursion occurs inmen than in women. Given that men are typically taller than women, the…

  17. Relation of Phanerozoic stable isotope excursions to climate, bacterial metabolism, and major extinctions

    PubMed Central

    Stanley, Steven M.

    2010-01-01

    Conspicuous global stable carbon isotope excursions that are recorded in marine sedimentary rocks of Phanerozoic age and were associated with major extinctions have generally paralleled global stable oxygen isotope excursions. All of these phenomena are therefore likely to share a common origin through global climate change. Exceptional patterns for carbon isotope excursions resulted from massive carbon burial during warm intervals of widespread marine anoxic conditions. The many carbon isotope excursions that parallel those for oxygen isotopes can to a large degree be accounted for by the Q10 pattern of respiration for bacteria: As temperature changed along continental margins, where ∼90% of marine carbon burial occurs today, rates of remineralization of isotopically light carbon must have changed exponentially. This would have reduced organic carbon burial during global warming and increased it during global cooling. Also contributing to the δ13C excursions have been release and uptake of methane by clathrates, the positive correlation between temperature and degree of fractionation of carbon isotopes by phytoplankton at temperatures below ∼15°, and increased phytoplankton productivity during “icehouse” conditions. The Q10 pattern for bacteria and climate-related changes in clathrate volume represent positive feedbacks for climate change. PMID:21041682

  18. Highway driving safety the day after using sleep medication: the direction of lapses and excursions out-of-lane in drowsy drivers.

    PubMed

    Verster, Joris C; Mooren, Loes; Bervoets, Adriana C; Roth, Thomas

    2017-10-24

    The primary outcome measure of the on-road driving test is the Standard Deviation of Lateral Position. However, other outcome measures, such as lapses and excursions out-of-lane, also need to be considered as they may be related to crash risk. The aim of this study was to determine the direction of lapses and excursions out-of-lane (i.e. towards/into the adjacent traffic lane or towards/into the road shoulder). In total, data from 240 driving tests were re-analysed, and 628 lapses and 401 excursions out-of-lane were identified. The analyses revealed that lapses were made equally frequently over left (49.4%) and over right (43.3%). In contrast, excursions out-of-lane were almost exclusively directed over right into the (safer) road shoulder (97.3%). These findings suggest that drivers are unaware of having lapses, whereas excursions out-of-lane are events where the driver is aware of loss of vehicle control. © 2017 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.

  19. Modeling the Impact of Forest and Peat Fires on Carbon-Isotopic Compositions of Cretaceous Atmosphere and Vegetation

    NASA Astrophysics Data System (ADS)

    Finkelstein, D. B.; Pratt, L. M.

    2004-12-01

    Prevalence of wildfires or peat fires associated with seasonally dry conditions in the Cretaceous is supported by recent studies documenting the widespread presence of pyrolytic polycyclic aromatic hydrocarbons and fusinite. Potential roles of CO2 emissions from fire have been overlooked in many discussions of Cretaceous carbon-isotope excursions (excluding K-P boundary discussions). Enhanced atmospheric CO2 levels could increase fire frequency through elevated lightning activity. When biomass or peat is combusted, emissions of CO2 are more negative than atmospheric CO2. Five reservoirs (atmosphere, vegetation, soil, and shallow and deep oceans), and five fluxes (productivity, respiration, litter fall, atmosphere-ocean exchange, and surface-deep ocean exchange) were modeled as a closed system. The size of the Cretaceous peat reservoir was estimated by compilation of published early Cretaceous coal resources. Initial pCO2 was assumed to be 2x pre-industrial atmospheric levels (P.A.L.). Critical variables in the model are burning efficiency and post-fire growth rates. Assuming 1% of standing terrestrial biomass is consumed by wildfires each year for ten years (without combustion of peat), an increase of atmospheric CO2 (from 2.0 to 2.2x P.A.L.) and a negative carbon isotope excursion (-1.2 ‰ ) are recorded by both atmosphere and new growth. Net primary productivity linked to the residence time of the vegetation and soil reservoirs results in a negative isotope shift followed by a broad positive isotope excursion. Decreasing the rate of re-growth dampens this trailing positive shift and increases the duration of the excursion. Post-fire pCO2 and new growth returned to initial values after 72 years. Both negative and positive isotope excursions are recorded in the model in surface ocean waters. Exchange of CO2 with the surface- and deep-ocean dampens the isotopic shift of the atmosphere. Excursions are first recorded in the atmosphere (and new growth), followed by the ocean, vegetation, and soil reservoirs. Ten to twenty five-year cycles of drought and fire are not recorded as individual excursions in the soil reservoir as the rate of transfer between the vegetation and soil reservoirs homogenizes the signal. A wildfire-modeled excursion does not propagate a geologically significant excursion through time. Combustion of a peat reservoir is necessary to drive and validate a geologically and isotopically significant excursion. Assuming 0.5% of the standing early Cretaceous peat reservoir is consumed by fire for each year for ten years coupled with the earlier scenario, the atmospheric CO2 increases from 2.0 to 3.1x P.A.L., atmosphere, vegetation, and the surface ocean record a negative carbon isotope excursion of -5.1 ‰ , -3.8 ‰ and -1.8 ‰ respectively, with a duration of 741 years. Increasing the size of the vegetation reservoir translates the excursions from the centennial to millennial scale. For example, doubling the vegetation reservoir (from 1.4 to 2.8E+16 gC) for a 25 year global peat conflagration (0.5% combusted each year) results in a CO2 increase from 2.0 to 4.0x P.A.L., and the atmosphere, vegetation, and the surface ocean reservoirs with a negative carbon isotope excursion of -5.7 ‰ , -8.7 ‰ and -2.3 ‰ respectively. Addition of carbonaceous aerosols (black carbon and polycyclic aromatic hydrocarbons) to pelagic marine sediments could potentially serve as a high-resolution record of ancient fires and firmly tie isotopic shifts to paleofires.

  20. Assessment of vertical excursions and open-sea psychological performance at depths to 250 fsw.

    PubMed

    Miller, J W; Bachrach, A J; Walsh, J M

    1976-12-01

    A series of 10 two-man descending vertical excursion dives was carried out in the open sea from an ocean-floor habitat off the coast of Puerto Rico by four aquanauts saturated on a normoxic-nitrogen breathing mixture at a depth of 106 fsw. The purpose of these dives was two-fold: to validate laboratory findings with respect to decompression schedules and to determine whether such excursions would produce evidence of adaptation to nitrogen narcosis. For the latter, tests designed to measure time estimation, short-term memory, and auditory vigilance were used. The validation of experimental excursion tables was carried out without incidence of decompression sickness. Although no signs of nitrogen narcosis were noted during testing, all subjects made significantly longer time estimates in the habitat and during the excursions than on the surface. Variability and incomplete data prevented a statistical analysis of the short-term memory results, and the auditory vigilance proved unusable in the water.

  1. Human risk factors associated with pilots in runway excursions.

    PubMed

    Chang, Yu-Hern; Yang, Hui-Hua; Hsiao, Yu-Jung

    2016-09-01

    A breakdown analysis of civil aviation accidents worldwide indicates that the occurrence of runway excursions represents the largest portion among all aviation occurrence categories. This study examines the human risk factors associated with pilots in runway excursions, by applying a SHELLO model to categorize the human risk factors and to evaluate the importance based on the opinions of 145 airline pilots. This study integrates aviation management level expert opinions on relative weighting and improvement-achievability in order to develop four kinds of priority risk management strategies for airline pilots to reduce runway excursions. The empirical study based on experts' evaluation suggests that the most important dimension is the liveware/pilot's core ability. From the perspective of front-line pilots, the most important risk factors are the environment, wet/containment runways, and weather issues like rain/thunderstorms. Finally, this study develops practical strategies for helping management authorities to improve major operational and managerial weaknesses so as to reduce the human risks related to runway excursions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. The metatarsosesamoid joint: an in vitro 3D quantitative assessment.

    PubMed

    Jamal, Bilal; Pillai, Anand; Fogg, Quentin; Kumar, Senthil

    2015-03-01

    The anatomy of the first metatarsophalangeal (MTP) joint, particularly the metatarsosesamoid articulation, remains poorly understood. Our goal was to quantitatively define the excursion of the sesamoids. Seven cadavers were dissected to assess the articulating surfaces throughout a normal range of motion. The dissections were digitally reconstructed in various positions using a MicroScribe. For first MTP joint, excursion averaged 14.7mm for the tibial sesamoid in the sagittal plane and 7.5mm for the fibular sesamoid. The sesamoids also moved medially to laterally when the joint was dorsiflexed. For the maximally dorsiflexed joint, excursion averaged 2.8mm for the tibial sesamoid and 3.5mm for the fibular sesamoid. Hallucal sesamoids appear to have differential tracking: the tibial sesamoid has greater longitudinal excursion; the fibular sesamoid has greater lateral excursion. The anatomical data will interest those involved with the design of an effective hallux arthroplasty. Copyright © 2014 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

  3. Geomagnetic field excursion recorded 17 ka at Tianchi Volcano, China: New 40Ar/39Ar age and significance

    NASA Astrophysics Data System (ADS)

    Singer, Brad S.; Jicha, Brian R.; He, Huaiyu; Zhu, Rixiang

    2014-04-01

    New 40Ar/39Ar dating of a comenditic lava atop Tianchi Volcano, China, indicates eruption at 17.1 ± 0.9 ka. The flow interior records a pair of transitional virtual geomagnetic poles and a low paleointensity of ~25 μT. Thus, it records a geomagnetic field excursion that is younger than the 41 ka Laschamp or 32 ka Auckland excursions. Implications are: (1) following a repose of several tens of kyr, Tianchi Volcano became highly active immediately following termination of the last glaciation maximum. The flare-up of silicic eruptions may reflect rapid deglaciation of the edifice. (2) A 17 ka age for the Tianchi excursion provides the first direct radioisotopic evidence that excursional behavior, which is imprecisely dated and less well documented magnetically at several other sites, is a global feature of geodynamo behavior. (3) During the Brunhes chron, 13 well-dated excursions cluster into two periods, including seven between 17 and 212 ka, and six between about 530 and 730 ka.

  4. Record of the Late Devonian Hangenberg global positive carbon-isotope excursion in an epeiric sea setting: Carbonate production, organic-carbon burial and paleoceanography during the late Famennian

    USGS Publications Warehouse

    Cramer, Bradley D.; Saltzman, Matthew R.; Day, J.E.; Witzke, B.J.

    2008-01-01

    Latest Famennian marine carbonates from the mid-continent of North America were examined to investigate the Late Devonian (very late Famennian) Hangenberg positive carbon-isotope (??13 Ccarb) excursion. This global shift in the ?? 13C of marine waters began during the late Famennian Hangenberg Extinction Event that occurred during the Middle Siphonodella praesulcata conodont zone. The post-extinction recovery interval spans the Upper S. praesulcata Zone immediately below the Devonian-Carboniferous boundary. Positive excursions in ?? 13 Ccarb are often attributed to the widespread deposition of organic-rich black shales in epeiric sea settings. The Hangenberg ??13 Ccarb excursion documented in the Louisiana Limestone in this study shows the opposite trend, with peak ??13 Ccarb values corresponding to carbonate production in the U.S. mid-continent during the highstand phase of the very late Famennian post-glacial sea level rise. Our data indicate that the interval of widespread black shale deposition (Hangenberg Black Shale) predates the peak isotope values of the Hangenberg ??13 Ccarb excursion and that peak values of the Hangenberg excursion in Missouri are not coincident with and cannot be accounted for by high Corg burial in epeiric seas. We suggest instead that sequestration and burial of Corg in the deep oceans drove the peak interval of the ??13Ccarb excursion, as a result of a change in the site of deep water formation to low-latitude epeiric seas as the global climate shifted between cold and warm states.

  5. A paleomagnetic record in loess-paleosol sequences since late Pleistocene in the arid Central Asia

    NASA Astrophysics Data System (ADS)

    Li, Guanhua; Xia, Dunsheng; Appel, Erwin; Wang, Youjun; Jia, Jia; Yang, Xiaoqiang

    2018-03-01

    Geomagnetic excursions during Brunhes epoch have been brought to the forefront topic in paleomagnetic study, as they provide key information about Earth's interior dynamics and could serve as another tool for stratigraphic correlation among different lithology. Loess-paleosol sequences provide good archives for decoding geomagnetic excursions. However, the detailed pattern of these excursions was not sufficiently clarified due to pedogenic influence. In this study, paleomagnetic analysis was performed in loess-paleosol sequences on the northern piedmont of the Tianshan Mountains (northwestern China). By radiocarbon and luminance dating, the loess section was chronologically constrained to mainly the last c.130 ka, a period when several distinct geomagnetic excursions were involved. The rock magnetic properties in this loess section are dominated by magnetite and maghemite in a pseudo-single-domain state. The rock magnetic properties and magnetic anisotropy indicate weakly pedogenic influence for magnetic record. The stable component of remanent magnetization derived from thermal demagnetization revealed the presence of two intervals of directional anomalies with corresponding intensity lows in the Brunhes epoch. The age control in the key layers indicates these anomalies are likely associated with the Laschamp and Blake excursions, respectively. In addition, relative paleointensity in the loess section is basically compatible with other regional and global relative paleointensity records and indicates two low-paleointensity zones, possibly corresponding to the Blake and Laschamp excursions, respectively. As a result, this study suggests that the loess section may have the potential to record short-lived excursions, which largely reflect the variation of dipole components in the global archives.

  6. Kinematic analysis of postural reactions to a posterior translation in rocker bottom shoes in younger and older adults.

    PubMed

    Kimel-Scott, Dorothy R; Gulledge, Elisha N; Bolena, Ryan E; Albright, Bruce C

    2014-01-01

    Shoes with rocker bottom soles are utilized by persons with diabetic peripheral neuropathy to reduce plantar pressures during gait. The risk of falls increases with age and is compounded by diabetic neuropathy. The purpose of this study was to analyze how rocker bottom shoes affect posture control of older adults (50-75 years old) and younger adults (20-35 years old) in response to posterior slide perturbations. The postural response to a posterior platform translation was normalized among subjects by applying the below threshold stepping velocity (BTSV) for each subject. The BTSV was the fastest velocity of platform translation that did not cause a stepping response while wearing the rocker bottom shoes. Joint excursion, time to first response, response time, and variability of mean peak joint angles were analyzed at the ankle, knee, hip, trunk, and head in the sagittal plane. The statistical analysis was a 2-factor mixed repeated measures design to determine interactions between and within shoe types and age groups. While wearing rocker bottom shoes, both age groups exhibited increased joint excursion, differences in time to initial response, and longer response time. The older group demonstrated decreased joint excursion and increased time to initial response compared to the younger group, as well as a significantly slower mean BTSV. These findings support the conclusion that in healthy older adults and in populations at risk for falls, the use of rocker bottom or other unstable shoes may increase the potential of falls when confronted with a standing perturbation such as a forceful slip or trip. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Engaging students in research learning experiences through hydrology field excursions and projects

    NASA Astrophysics Data System (ADS)

    Ewen, T.; Seibert, J.

    2014-12-01

    One of the best ways to engage students and instill enthusiasm for hydrology is to expose them to hands-on learning. A focus on hydrology field research can be used to develop context-rich and active learning, and help solidify idealized learning where students are introduced to individual processes through textbook examples, often neglecting process interactions and an appreciation for the complexity of the system. We introduced a field course where hydrological measurement techniques are used to study processes such as snow hydrology and runoff generation, while also introducing students to field research and design of their own field project. In the field projects, students design a low-budget experiment with the aim of going through the different steps of a 'real' scientific project, from formulating the research question to presenting their results. In one of the field excursions, students make discharge measurements in several alpine streams with a salt tracer to better understand the spatial characteristics of an alpine catchment, where source waters originate and how they contribute to runoff generation. Soil moisture measurements taken by students in this field excursion were used to analyze spatial soil moisture patterns in the alpine catchment and subsequently used in a publication. Another field excursion repeats a published experiment, where preferential soil flow paths are studied using a tracer and compared to previously collected data. For each field excursion, observational data collected by the students is uploaded to an online database we developed, which also allows students to retrieve data from past excursions to further analyze and compare their data. At each of the field sites, weather stations were installed and a webviewer allows access to realtime data from data loggers, allowing students to explore how processes relate to climatic conditions. With in-house film expertise, these field excursions were also filmed and short virtual excursions were produced, which we plan to use in a large introductory course, exposing students to field research at an early stage.

  8. Load Dependency of Postural Control--Kinematic and Neuromuscular Changes in Response to over and under Load Conditions.

    PubMed

    Ritzmann, Ramona; Freyler, Kathrin; Weltin, Elmar; Krause, Anne; Gollhofer, Albert

    2015-01-01

    Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL) and under loading (UL) used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms. Balance performance was recorded under normal loading (NL, 1 g), UL (0.16 g 0.38 g) and OL (1.8 g) in monopedal stance. Center of pressure (COP) displacement and frequency distribution (low 0.15-0.5 Hz (LF), medium 0.5-2 Hz (MF), high 2-6 Hz (HF)) as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios). Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL. Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal segments to adjust the center of gravity above the base of support.

  9. Chemistry of the Marlboro Clay in Virginia and Implications for the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Zimmer, M.; Cai, Y.; Corley, A.; Liang, J. A.; Powars, D.; Goldstein, S. L.; Kent, D. V.; Broecker, W. S.

    2017-12-01

    The Paleocene-Eocene Thermal Maximum (PETM) was a global hyperthermal ( 5ºC warming) event marked by a rapid carbon isotope excursion (CIE) of >1‰ in the marine carbonate record (e.g. Zeebe et al. Nature Geoscience 2009). Possible explanations for the CIE include intrusion of a sill complex into organic carbonate (Aarnes et al. J. Geol. Soc. 2015), dissolution of methane hydrates (Thomas et al. Geology 2002), and a comet impact event (Schaller et al. Science 2016). Here we present new data across the PETM from the VirginiaDEQ-USGS Surprise Hill (SH) core, Northumberland Co., VA. We analyzed the Marlboro Clay, a thick, kaolinite-rich clay unit that marks the initiation of the PETM in the mid-Atlantic Coastal Plain of North America, as well as units above and below it. Bulk sediment records a δ13C excursion of approximately -5‰ across the CIE, while benthic foraminifera (Cibicidoides spp.) record a synchronous excursion of approximately -4.5‰. These results are consistent with other records from the New Jersey Coastal Plain (Makarova et al. Paleoceanography 2017). The excursion coincides with an increase in magnetic susceptibility, a decrease in bulk CaCO3 content, and an 2.5‰ decrease of δ18O in both the bulk sediment and benthic foraminifera of the SH core. Pb isotope analyses of the <63 μm fraction sediments indicate a unique provenance make-up for the Marlboro Clay. The results of the study thus indicate that PETM Marlboro Clay was not generated simply by intensified weathering of the same source area as the underlying Aquia Formation and overlying Nanjemoy Formation. Any hypothesis that aims to explain the mechanism that triggered the PETM must also account for the observed distinct provenance make-up of the Marlboro Clay.

  10. Evidence of isometric function of the flexor hallucis longus muscle in normal gait.

    PubMed

    Kirane, Y M; Michelson, J D; Sharkey, N A

    2008-01-01

    Studying mechanics of the muscles spanning multiple joints provides insights into intersegmental dynamics and movement coordination. Multiarticular muscles are thought to function at "near-isometric" lengths to transfer mechanical energy between the adjacent body segments. Flexor hallucis longus (FHL) is a multiarticular flexor of the great toe; however, its potential isometric function has received little attention. We used a robotic loading apparatus to investigate FHL mechanics during simulated walking in cadaver feet, and hypothesized that physiological force transmission across the foot can occur with isometric FHL function. The extrinsic foot tendons, stripped of the muscle fibers, were connected to computer-controlled linear actuators. The FHL activity was controlled using force-feedback (FC) based upon electromyographic data from healthy subjects, and subsequently, isometric positional feedback (PC), maintaining the FHL myotendinous junction stationary during simulated walking. Tendon forces and excursions were recorded, as were the strains within the first metatarsal. Forces in the metatarsal and metatarsophalangeal joint were derived from these strains. The FHL tendon excursion under FC was 6.57+/-3.13mm. The forces generated in the FHL tendon, metatarsal and metatarsophalangeal joint with the FHL under isometric PC were not significantly different in pattern from FC. These observations provide evidence that physiological forces could be generated along the great toe with isometric FHL function. A length servo mechanism such as the stretch reflex could likely control the isometric FHL function during in vivo locomotion; this could have interesting implications regarding the conditions of impaired stretch reflex such as spastic paresis and peripheral neuropathies.

  11. Linking nanoscale mechanical behavior to bulk physical properties and phenomena of energetic materials

    NASA Astrophysics Data System (ADS)

    Taw, Matthew R.

    The hardness and reduced modulus of aspirin, RDX, HMX, TATB, FOX-7, ADAAF, and TNT/CL-20 were experimentally measured with nanoindentation. These values are reported for the first time using as-received micron sized crystals of energetic materials with no additional mechanical processing. The results for TATB, ADAAF, and TNT/CL-20 are the first of their kind, while comparisons to previous nanoindentation studies on large, carefully grown single crystals of the other energetic materials show that mechanical properties of the larger crystals are comparable to crystals in the condition they are practically used. Measurements on aspirin demonstrate the variation that can occur between nanoindentation indents based on the orientation of a Berkovich tip relative to the surface of the sample. The Hertzian elastic contact model was used to analyze the materials initial yield, or pop-in, behavior. The length, energy, indentation load, and shear stress at initial yielding were used to characterize each material. For the energetic materials the length and energy of the yield excursions were compared to the drop weight sensitivity. This comparison revealed a general trend that more impact sensitive materials have longer, more severe pop-in excursions. Hot spot initiation mechanisms involving crystal defects such as void collapses and dislocation pile-up followed by avalanche are supported by these trends. While this only takes one aspect of impact sensitivity into consideration, if this trend is observed in a larger range of energetics these methods could possibly be used to great advantage in the early stages of new explosives synthesis to obtain an estimation of drop weight sensitivity.

  12. Altered Tibiofemoral Joint Contact Mechanics and Kinematics in Patients with Knee Osteoarthritis and Episodic Complaints of Joint Instability

    PubMed Central

    Farrokhi, Shawn; Voycheck, Carrie A.; Klatt, Brian A.; Gustafson, Jonathan A.; Tashman, Scott; Fitzgerald, G. Kelley

    2014-01-01

    Background To evaluate knee joint contact mechanics and kinematics during the loading response phase of downhill gait in knee osteoarthritis patients with self-reported instability. Methods Forty-three subjects, 11 with medial compartment knee osteoarthritis and self-reported instability (unstable), 7 with medial compartment knee osteoarthritis but no reports of instability (stable), and 25 without knee osteoarthritis or instability (control) underwent Dynamic Stereo X-ray analysis during a downhill gait task on a treadmill. Findings The medial compartment contact point excursions were longer in the unstable group compared to the stable (p=0.046) and the control groups (p=0.016). The peak medial compartment contact point velocity was also greater for the unstable group compared to the stable (p=0.047) and control groups (p=0.022). Additionally, the unstable group demonstrated a coupled movement pattern of knee extension and external rotation after heel contact which was different than the coupled motion of knee flexion and internal rotation demonstrated by stable and control groups. Interpretation Our findings suggest that knee joint contact mechanics and kinematics are altered during the loading response phase of downhill gait in knee osteoarthritis patients with self-reported instability. The observed longer medial compartment contact point excursions and higher velocities represent objective signs of mechanical instability that may place the arthritic knee joint at increased risk for disease progression. Further research is indicated to explore the clinical relevance of altered contact mechanics and kinematics during other common daily activities and to assess the efficacy of rehabilitation programs to improve altered joint biomechanics in knee osteoarthritis patients with self-reported instability. PMID:24856791

  13. Brownian Ratchet Mechanism for Faithful Segregation of Low-Copy-Number Plasmids.

    PubMed

    Hu, Longhua; Vecchiarelli, Anthony G; Mizuuchi, Kiyoshi; Neuman, Keir C; Liu, Jian

    2017-04-11

    Bacterial plasmids are extrachromosomal DNA that provides selective advantages for bacterial survival. Plasmid partitioning can be remarkably robust. For high-copy-number plasmids, diffusion ensures that both daughter cells inherit plasmids after cell division. In contrast, most low-copy-number plasmids need to be actively partitioned by a conserved tripartite ParA-type system. ParA is an ATPase that binds to chromosomal DNA; ParB is the stimulator of the ParA ATPase and specifically binds to the plasmid at a centromere-like site, parS. ParB stimulation of the ParA ATPase releases ParA from the bacterial chromosome, after which it takes a long time to reset its DNA-binding affinity. We previously demonstrated in vitro that the ParA system can exploit this biochemical asymmetry for directed cargo transport. Multiple ParA-ParB bonds can bridge a parS-coated cargo to a DNA carpet, and they can work collectively as a Brownian ratchet that directs persistent cargo movement with a ParA-depletion zone trailing behind. By extending this model, we suggest that a similar Brownian ratchet mechanism recapitulates the full range of actively segregated plasmid motilities observed in vivo. We demonstrate that plasmid motility is tuned as the replenishment rate of the ParA-depletion zone progressively increases relative to the cargo speed, evolving from diffusion to pole-to-pole oscillation, local excursions, and, finally, immobility. When the plasmid replicates, the daughters largely display motilities similar to that of their mother, except that when the single-focus progenitor is locally excursive, the daughter foci undergo directed segregation. We show that directed segregation maximizes the fidelity of plasmid partition. Given that local excursion and directed segregation are the most commonly observed modes of plasmid motility in vivo, we suggest that the operation of the ParA-type partition system has been shaped by evolution for high fidelity of plasmid segregation. Published by Elsevier Inc.

  14. Glucose excursions and glycaemic control during Ramadan fasting in diabetic patients: insights from continuous glucose monitoring (CGM).

    PubMed

    Lessan, N; Hannoun, Z; Hasan, H; Barakat, M T

    2015-02-01

    Ramadan fasting represents a major shift in meal timing and content for practicing Muslims. This study used continuous glucose monitoring (CGM) to assess changes in markers of glycaemic excursions during Ramadan fasting to investigate the short-term safety of this practice in different groups of patients with diabetes. A total of 63 subjects (56 with diabetes, seven healthy volunteers; 39 male, 24 female) had CGM performed during, before and after Ramadan fasting. Mean CGM curves were constructed for each group for these periods that were then used to calculate indicators of glucose control and excursions. Post hoc data analyses included comparisons of different medication categories (metformin/no medication, gliptin, sulphonylurea and insulin). Medication changes during Ramadan followed American Diabetes Association guidelines. Among patients with diabetes, there was a significant difference in mean CGM curve during Ramadan, with a slow fall during fasting hours followed by a rapid rise in glucose level after the sunset meal (iftar). The magnitude of this excursion was greatest in the insulin-treated group, followed by the sulphonylurea-treated group. Markers of control deteriorated in a small number (n=3) of patients. Overall, whether fasting or non-fasting, subjects showed no statistically significant changes in mean interstitial glucose (IG), mean amplitude of glycaemic excursion (MAGE), high and low blood glucose indices (HBGI/LBGI), and number of glucose excursions and rate of hypoglycaemia. The main change in glycaemic control with Ramadan fasting in patients with diabetes is in the pattern of excursions. Ramadan fasting caused neither overall deterioration nor improvement in the majority of patients with good baseline glucose control. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  15. Comparison of Diaphragmatic Breathing Exercise, Volume and Flow Incentive Spirometry, on Diaphragm Excursion and Pulmonary Function in Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Trial

    PubMed Central

    Anand, R.

    2016-01-01

    Objective. To evaluate the effects of diaphragmatic breathing exercises and flow and volume-oriented incentive spirometry on pulmonary function and diaphragm excursion in patients undergoing laparoscopic abdominal surgery. Methodology. We selected 260 patients posted for laparoscopic abdominal surgery and they were block randomization as follows: 65 patients performed diaphragmatic breathing exercises, 65 patients performed flow incentive spirometry, 65 patients performed volume incentive spirometry, and 65 patients participated as a control group. All of them underwent evaluation of pulmonary function with measurement of Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1), Peak Expiratory Flow Rate (PEFR), and diaphragm excursion measurement by ultrasonography before the operation and on the first and second postoperative days. With the level of significance set at p < 0.05. Results. Pulmonary function and diaphragm excursion showed a significant decrease on the first postoperative day in all four groups (p < 0.001) but was evident more in the control group than in the experimental groups. On the second postoperative day pulmonary function (Forced Vital Capacity) and diaphragm excursion were found to be better preserved in volume incentive spirometry and diaphragmatic breathing exercise group than in the flow incentive spirometry group and the control group. Pulmonary function (Forced Vital Capacity) and diaphragm excursion showed statistically significant differences between volume incentive spirometry and diaphragmatic breathing exercise group (p < 0.05) as compared to that flow incentive spirometry group and the control group. Conclusion. Volume incentive spirometry and diaphragmatic breathing exercise can be recommended as an intervention for all patients pre- and postoperatively, over flow-oriented incentive spirometry for the generation and sustenance of pulmonary function and diaphragm excursion in the management of laparoscopic abdominal surgery. PMID:27525116

  16. Comparison of Diaphragmatic Breathing Exercise, Volume and Flow Incentive Spirometry, on Diaphragm Excursion and Pulmonary Function in Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Trial.

    PubMed

    Alaparthi, Gopala Krishna; Augustine, Alfred Joseph; Anand, R; Mahale, Ajith

    2016-01-01

    Objective. To evaluate the effects of diaphragmatic breathing exercises and flow and volume-oriented incentive spirometry on pulmonary function and diaphragm excursion in patients undergoing laparoscopic abdominal surgery. Methodology. We selected 260 patients posted for laparoscopic abdominal surgery and they were block randomization as follows: 65 patients performed diaphragmatic breathing exercises, 65 patients performed flow incentive spirometry, 65 patients performed volume incentive spirometry, and 65 patients participated as a control group. All of them underwent evaluation of pulmonary function with measurement of Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1), Peak Expiratory Flow Rate (PEFR), and diaphragm excursion measurement by ultrasonography before the operation and on the first and second postoperative days. With the level of significance set at p < 0.05. Results. Pulmonary function and diaphragm excursion showed a significant decrease on the first postoperative day in all four groups (p < 0.001) but was evident more in the control group than in the experimental groups. On the second postoperative day pulmonary function (Forced Vital Capacity) and diaphragm excursion were found to be better preserved in volume incentive spirometry and diaphragmatic breathing exercise group than in the flow incentive spirometry group and the control group. Pulmonary function (Forced Vital Capacity) and diaphragm excursion showed statistically significant differences between volume incentive spirometry and diaphragmatic breathing exercise group (p < 0.05) as compared to that flow incentive spirometry group and the control group. Conclusion. Volume incentive spirometry and diaphragmatic breathing exercise can be recommended as an intervention for all patients pre- and postoperatively, over flow-oriented incentive spirometry for the generation and sustenance of pulmonary function and diaphragm excursion in the management of laparoscopic abdominal surgery.

  17. A carbon isotopic and sedimentological record of the latest Devonian (Famennian) from the Western U.S. and Germany

    USGS Publications Warehouse

    Myrow, P.M.; Strauss, J.V.; Creveling, J.R.; Sicard, K.R.; Ripperdan, R.; Sandberg, C.A.; Hartenfels, S.

    2011-01-01

    New carbon isotopic data from upper Famennian deposits in the western United States reveal two previously unrecognized major positive isotopic excursions. The first is an abrupt ~. 3??? positive excursion, herein referred to as ALFIE (A Late Famennian Isotopic Excursion), recorded in two sections of the Pinyon Peak Limestone of north-central Utah. Integration of detailed chemostratigraphic and biostratigraphic data suggests that ALFIE is the Laurentian record of the Dasberg Event, which has been linked to transgression in Europe and Morocco. Sedimentological data from the Chaffee Group of western Colorado also record transgression at a similar biostratigraphic position, with a shift from restricted to open-marine lithofacies. ALFIE is not evident in chemostratigraphic data from age-equivalent strata in Germany studied herein and in southern Europe, either because it is a uniquely North American phenomenon, or because the German sections are too condensed relative to those in Laurentia. A second positive carbon isotopic excursion from the upper Chaffee Group of Colorado is recorded in transgressive strata deposited directly above a previously unrecognized paleokarst interval. The age of this excursion, and the duration of the associated paleokarst hiatus, are not well constrained, although the events occurred sometime after the Late Famennian Middle expansa Zone. The high positive values recorded in this excursion are consistent with those associated with the youngest Famennian Middle to Late praesulcata Hangenberg Isotopic Excursion in Europe, the isotopic expression of the Hangenberg Event, which included mass extinction, widespread black shale deposition, and a glacio-eustatic fall and rise. If correct, this would considerably revise the age of the Upper Chaffee Group strata of western Colorado. ?? 2011 Elsevier B.V.

  18. Duration of and decoupling between carbon isotope excursions during the end-Triassic mass extinction and Central Atlantic Magmatic Province emplacement

    NASA Astrophysics Data System (ADS)

    Yager, Joyce A.; West, A. Joshua; Corsetti, Frank A.; Berelson, William M.; Rollins, Nick E.; Rosas, Silvia; Bottjer, David J.

    2017-09-01

    Changes in δ13Ccarb and δ13Corg from marine strata occur globally in association with the end-Triassic mass extinction and the emplacement of the Central Atlantic Magmatic Province (CAMP) during the break up of Pangea. As is typical in deep time, the timing and duration of these isotopic excursions has remained elusive, hampering attempts to link carbon cycle perturbations to specific processes. Here, we report δ13Ccarb and δ13Corg from Late Triassic and Early Jurassic strata near Levanto, Peru, where intercalated dated ash beds permit temporal calibration of the carbon isotope record. Both δ13Ccarb and δ13Corg exhibit a broad positive excursion through the latest Triassic into the earliest Jurassic. The first order positive excursion in δ13Corg is interrupted by a negative shift noted in many sections around the world coincident with the extinction horizon. Our data indicate that the negative excursion lasts 85 ± 25 kyrs, longer than inferred by previous studies based on cyclostratigraphy. A 260 ± 80 kyr positive δ13Corg shift follows, during which the first Jurassic ammonites appear. The overall excursion culminates in a return to pre-perturbation carbon isotopic values over the next 1090 ± 70 kyrs. Via chronologic, isotopic, and biostratigraphic correlation to other successions, we find that δ13Ccarb and δ13Corg return to pre-perturbation values as CAMP volcanism ceases and in association with the recovery of pelagic and benthic biota. However, the initiation of the carbon isotope excursion at Levanto predates the well-dated CAMP sills from North America, indicating that CAMP may have started earlier than thought based on these exposures, or that the onset of carbon cycle perturbations was not related to CAMP.

  19. APOLLO/SATURN (A/S) 201 - LAUNCH - CAPE

    NASA Image and Video Library

    1966-02-26

    A/S 201 was launched from the Kennedy Space Center Launch Complex 34 at 11:12 a.m., 02/26/1966. The instrumented Apollo Command and Service Module, and, a spacecraft Lunar Excursion Module Adapter, was successfully launched on the unmanned suborbital mission by the Saturn 1B to check spacecraft launch vehicle mechanical compatibility and to test the spacecraft heat shield in a high-velocity re-entry mode. CAPE KENNEDY, FL

  20. Explosive eruption of coal and basalt and the end-Permian mass extinction

    PubMed Central

    Ogden, Darcy E.; Sleep, Norman H.

    2012-01-01

    The end-Permian extinction decimated up to 95% of carbonate shell-bearing marine species and 80% of land animals. Isotopic excursions, dissolution of shallow marine carbonates, and the demise of carbonate shell-bearing organisms suggest global warming and ocean acidification. The temporal association of the extinction with the Siberia flood basalts at approximately 250 Ma is well known, and recent evidence suggests these flood basalts may have mobilized carbon in thick deposits of organic-rich sediments. Large isotopic excursions recorded in this period are potentially explained by rapid venting of coal-derived methane, which has primarily been attributed to metamorphism of coal by basaltic intrusion. However, recently discovered contemporaneous deposits of fly ash in northern Canada suggest large-scale combustion of coal as an additional mechanism for rapid release of carbon. This massive coal combustion may have resulted from explosive interaction with basalt sills of the Siberian Traps. Here we present physical analysis of explosive eruption of coal and basalt, demonstrating that it is a viable mechanism for global extinction. We describe and constrain the physics of this process including necessary magnitudes of basaltic intrusion, mixing and mobilization of coal and basalt, ascent to the surface, explosive combustion, and the atmospheric rise necessary for global distribution. PMID:22184229

  1. Hydrogen mobility in transition zone silicates

    NASA Astrophysics Data System (ADS)

    Caracas, Razvan; Panero, Wendy R.

    2017-12-01

    We study the hydrogen mobility in ringwoodite and wadsleyite considering multiple charge-balanced defects, including Mg < = > 2H, Si < = > Mg + 2H, and the hydrogarnet defect, Si < = > 4H, using molecular dynamics simulations based on the density functional theory at transition zone pressures and temperatures between 1500 and 2500 K. We determine the diffusion coefficients and study in detail the mechanism of hydrogen mobility during lengthy simulations. Our results show that temperature, water concentration, and defect mechanism have a significant effect on mobility. We find that the fastest diffusion is for the Mg < = > 2H defect, while H is more mobile when incorporated as Si < = > Mg + 2H than as hydrogarnet defects. The computed diffusivities for ringwoodite are larger than for wadsleyite: at 2000 K, diffusivity is 1.13 × 10-09 m2/s for ringwoodite compared to 0.93 × 10-09 m2/s for wadsleyite. In general, the hydrogen atoms spend on the order of tens of picoseconds or more trapped in or around the vacancy sites with net migration between sites over timescales of tens of femtoseconds. At 2500 K, some of these hydrogen excursions take place over several angstroms, while at 2000 K, they do not always result in net diffusion. At 1500 K, most of the defects fail to make excursions from their defect sites resulting in diffusion.

  2. Fission yield and criticality excursion code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blanchard, A.

    2000-06-30

    The ANSI/ANS 8.3 standard allows a maximum yield not to exceed 2 x 10 fissions to calculate requiring the alarm system to be effective. It is common practice to use this allowance or to develop some other yield based on past criticality accident history or excursion experiments. The literature on the subject of yields discusses maximum yields larger and somewhat smaller than the ANS 8.3 permissive value. The ability to model criticality excursions and vary the various parameters to determine a credible maximum yield for operational specific cases has been available for some time but is not in common usemore » by criticality safety specialists. The topic of yields for various solution, metal, oxide powders, etc. in various geometry's and containers has been published by laboratory specialists or university staff and students for many decades but have not been available to practitioners. The need for best-estimate calculations of fission yields with a well-validated criticality excursion code has long been recognized. But no coordinated effort has been made so far to develop a generalized and well-validated excursion code for different types of systems. In this paper, the current practices to estimate fission yields are summarized along with its shortcomings for the 12-Rad zone (at SRS) and Criticality Alarm System (CAS) calculations. Finally the need for a user-friendly excursion code is reemphasized.« less

  3. Scaphoid tuberosity excursion is minimized during a dart-throwing motion: A biomechanical study.

    PubMed

    Werner, Frederick W; Sutton, Levi G; Basu, Niladri; Short, Walter H; Moritomo, Hisao; St-Amand, Hugo

    2016-01-01

    The purpose of this study was to determine whether the excursion of the scaphoid tuberosity and therefore scaphoid motion is minimized during a dart-throwing motion. Scaphoid tuberosity excursion was studied as an indicator of scaphoid motion in 29 cadaver wrists as they were moved through wrist flexion-extension, radioulnar deviation, and a dart-throwing motion. Study results demonstrate that excursion was significantly less during the dart-throwing motion than during either wrist flexion-extension or radioulnar deviation. If the goal of early wrist motion after carpal ligament or distal radius injury and reconstruction is to minimize loading of the healing structures, a wrist motion in which scaphoid motion is minimal should reduce length changes in associated ligamentous structures. Therefore, during rehabilitation, if a patient uses a dart-throwing motion that minimizes his or her scaphoid tuberosity excursion, there should be minimal changes in ligament loading while still allowing wrist motion. Bench research, biomechanics, and cross-sectional. Not applicable. The study was laboratory based. Copyright © 2016 Hanley & Belfus. Published by Elsevier Inc. All rights reserved.

  4. 22. WILEY CITY LINE BICENTENNIAL EXCURSION TROLLEY NEAR CONGDON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. WILEY CITY LINE - BICENTENNIAL EXCURSION TROLLEY NEAR CONGDON CASTLE - Yakima Valley Transportation Company Interurban Railroad, Connecting towns of Yakima, Selah & Wiley City, Yakima, Yakima County, WA

  5. Chronic neuromuscular electrical stimulation of paralyzed hindlimbs in a rodent model.

    PubMed

    Jung, Ranu; Ichihara, Kazuhiko; Venkatasubramanian, Ganapriya; Abbas, James J

    2009-10-15

    Neuromuscular electrical stimulation (NMES) can be used to activate paralyzed or paretic muscles to generate functional or therapeutic movements. The goal of this research was to develop a rodent model of NMES-assisted movement therapy after spinal cord injury (SCI) that will enable investigation of mechanisms of NMES-induced plasticity, from the molecular to systems level. Development of the model requires accurate mapping of electrode and muscle stimulation sites, the capability to selectively activate muscles to produce graded contractions of sufficient strength, stable anchoring of the implanted electrode within the muscles and stable performance with functional reliability over several weeks of the therapy window. Custom designed electrodes were implanted chronically in hindlimb muscles of spinal cord transected rats. Mechanical and electrical stability of electrodes and the ability to achieve appropriate muscle recruitment and joint angle excursion were assessed by characterizing the strength duration curves, isometric torque recruitment curves and kinematics of joint angle excursion over 6-8 weeks post implantation. Results indicate that the custom designed electrodes and implantation techniques provided sufficient anchoring and produced stable and reliable recruitment of muscles both in the absence of daily NMES (for 8 weeks) as well as with daily NMES that is initiated 3 weeks post implantation (for 6 weeks). The completed work establishes a rodent model that can be used to investigate mechanisms of neuroplasticity that underlie NMES-based movement therapy after spinal cord injury and to optimize the timing of its delivery.

  6. Author Correction: Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    PubMed

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-05-12

    In the original publication, the article title was incorrectly published as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of failing'. The correct title should read as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling'.

  7. Brownian excursions on combs

    NASA Astrophysics Data System (ADS)

    Dean, David S.; Jansons, Kalvis M.

    1993-03-01

    In this paper we use techniques from Ito excursion theory to analyze Brownian motion on generalized combs. Ito excursion theory is a little-known area of probability theory and we therefore present a brief introduction for the uninitiated. A general method for analyzing transport along the backbone of the comb is demonstrated and the specific case of a comb whose teeth are scaling branching trees is examined. We then present a recursive method for evaluating the distribution of the first passage times on hierarchical combs.

  8. Nonstationary envelope process and first excursion probability.

    NASA Technical Reports Server (NTRS)

    Yang, J.-N.

    1972-01-01

    The definition of stationary random envelope proposed by Cramer and Leadbetter, is extended to the envelope of nonstationary random process possessing evolutionary power spectral densities. The density function, the joint density function, the moment function, and the crossing rate of a level of the nonstationary envelope process are derived. Based on the envelope statistics, approximate solutions to the first excursion probability of nonstationary random processes are obtained. In particular, applications of the first excursion probability to the earthquake engineering problems are demonstrated in detail.

  9. Environmental control on the paleo- and environmental magnetic record on the Yermak Plateau, Arctic Ocean

    NASA Astrophysics Data System (ADS)

    Wiers, Steffen; Snowball, Ian; O'Regan, Matt; Almqvist, Bjarne

    2017-04-01

    The Yermak Plateau, situated north of Svalbard, has been recognized as one of several places in the Arctic Ocean where paleomagnetism yields controversial results. Despite low sedimentation rates, excursional paleomagnetic directions have been reconstructed from many cores in the region. Commonly reported geomagnetic excursions, i.e. Laschamp, Norwegian-Greenland-Sea and Blake, show considerably longer durations and younger ages compared to established short-lived geomagnetic polarity microchrons. An environmental control on the paleomagnetic record, connected to self-reversal during maghemitization of titanomagnetite has been proposed as one explanation for the wide occurrence of anomalous paleomagnetic data in the Arctic Ocean, but it remains unclear what mechanisms are responsible. Without independent stratigraphic control and independent dating it is difficult to distinguish between true and false records of the paleomagnetic field. Here we present a paleo- and environmental magnetic record from an 8.6 m long oriented Kasten core (PS92/39-02) collected at 1464 m water depth on the Yermak Plateau (81.94°N 13.82°E). The density and magnetic susceptibility fit well into the regional stratigraphy and allow for correlation of different parameters with independently dated records. During AF demagnetization zones with a weak-medium gyro-remanence and/or spurious ARM acquisition were observed at fields above 70 mT, but in some instances above 50 mT, coinciding with shallow to positive inclination zones. Based on a gyro-cleaned record the initial paleomagnetic age model fits well into the regional constraints. The top of the core was assigned to be recent, the first observed excursion was assigned to Laschamp (ca. 41ka), the second to Norwegian-Greenland Sea (ca. 70-80 ka) and the top of the third to Blake (ca. 110 ka). With no excursions observed below Blake, the bottom of the sediment sequence was assumed to be younger than 180 ka (the age of the Iceland Basin/Pringle Falls excursion). We applied this basic age model to kARM/k (magnetic grain size proxy) and the resulting temporal trend is very similar to the global oxygen isotope record of ice volume. The waxing and waning of the Svalbard-Barent Sea Ice Sheet is the main control on terrigenous input to the Yermak Plateau and thus link d18O and magnetic grain-size. With records spanning more than 2-3 glacial cycles orbital tuning could further support our findings. Finally, we propose the use of magnetic grain-size (as of kARM/k) as an independent tuning mechanism for dating sediments from the Yermak Plateau.

  10. Sulfur cycling in plays an important role in the development of Ocean Anoxic Events

    NASA Astrophysics Data System (ADS)

    Gomes, M. L.; Raven, M. R.; Fike, D. A.; Gill, B. C.; Johnston, D. T.

    2017-12-01

    Ocean Anoxic Events (OAEs) are major carbon cycle perturbations marked by enhanced organic carbon deposition in the marine realm and carbon isotope excursions in organic and inorganic carbon. Although not as severe as the "big five" mass extinctions, OAEs had dire consequences for marine ecosystems and thus influenced Mesozoic evolutionary patterns. Sulfur cycle reconstructions provide insight into the biogeochemical processes that played a role in the development of OAEs because the sulfur cycle is linked with the carbon and oxygen cycles. We present sulfur and oxygen isotope records from carbonate-associated sulfate from the Toarcian OAE that documents a positive sulfate-oxygen isotope excursion of +6‰, which is similar to the magnitude of the positive sulfur isotope excursion documented at the same site and other globally distributed sites. This high-resolution record allows us to explore temporal variability in the onset of the isotopic excursions: the onset of the positive sulfate-oxygen isotope excursion occurs at the same stratigraphic interval as the onset of the positive carbon isotope excursion and both precede the onset of the positive sulfate-sulfur isotope excursion. Because oxygen is rapidly recycled during oxidative sulfur cycling, changes in oxidative sulfur cycling affect oxygen isotope values of sulfate without impacting sulfur isotope values. Thus, the early onset of the sulfate-oxygen isotope excursion implies a change in oxidative sulfur cycling, which is likely due to a shoaling of the zone of sulfate reduction. We explore the consequences of sulfate reduction zone shoaling for organic carbon preservation. Specifically, the sulfurization of organic matter, which makes organic matter less susceptible to degradation, occurs more rapidly when the top of the zone of sulfate reduction is near or above the sediment water interface. Therefore, we suggest that the shoaling of the sulfate reduction zone locally changed pathways of oxidative sulfur cycling and enhanced organic carbon preservation. Given synchronous changes in similar, globally-distributed depositional environments, this impacted the global biogeochemical cycles of oxygen, carbon, and nutrients in ways that sustained decreased oxygen availability and influenced extinction patterns of marine organisms.

  11. An Excursion in Applied Mathematics.

    ERIC Educational Resources Information Center

    von Kaenel, Pierre A.

    1981-01-01

    An excursion in applied mathematics is detailed in a lesson deemed well-suited for the high school student or undergraduate. The problem focuses on an experimental missile guidance system simulated in the laboratory. (MP)

  12. Influence of magnetic pressure on stellar structure: A Mechanism for solar variability

    NASA Technical Reports Server (NTRS)

    Schatten, K. H.; Endal, A. S.

    1980-01-01

    A physical mechanism is proposed that couples the Sun's dynamo magnetic field to its gravitational potential energy. The mechanism involves the isotropic field pressure resulting in a lifting force on the convective envelope, thereby raising its potential energy. Decay of the field due to solar activity allows the envelop to subside and releases this energy, which can augment the otherwise steady solar luminosity. Equations are developed and applied to the Sun for several field configurations. The best estimate model suggests that uniform luminosity variations as large as 0.02% for half a sunspot cycle may occur. Brief temporal variations or the rotation of spatial structures could allow larger excursions in the energy released.

  13. Instant axis of rotation of L4-5 motion segment--a biomechanical study on cadaver lumbar spine.

    PubMed

    Sengupta, Dilip K; Demetropoulos, Constantine K; Herkowitz, Harry N

    2011-06-01

    The instant axis of rotation (IAR) is an important kinematic property to characterise of lumbar spine motion. The goal of this biomechanical study on cadaver lumbar spine was to determine the excursion of the IAR for flexion (FE), lateral bending (LB) and axial rotation (AR) motion at L4-5 segment. Ten cadaver lumbar spine specimens were tested in a 6 degrees-of-freedom spine tester with continuous clyclical loading using pure moment and follower pre-load, to produce physiological motion. The specimens were x-rayed and CT scanned prior to testing to identify marker position. Continuous motion tracking was done by Optotrak motion capture device. A continuous tracking of the IAR excursion was calculated from the continuous motions capturedata using a computer programme. IAR translates forward in flexion and backwards in extension with mean excursion of 26.5 mm (+/- 5.6 SD). During LB motion, IAR translates laterally in the same direction, and the mean excursion was 15.35 mm (+/- 8.75 SD). During axial rotation the IAR translates in the horizontal plane in a semicircular arc, around the centre of the vertebral body, but the IAR translates in the opposite direction of rotation. The IAR excursion was faster and larger during neutral zone motion in FE and LB, but uniform for AR motion. This is the first published data on the continuous excursion of IAR of a lumbar motion segment. The methodology is accurate and precise, but not practicable for in vivo testing.

  14. Iodine-to-calcium ratios in carbonates suggest a primary origin for the Precambrian Lomagundi and Shuram carbon isotope excursions

    NASA Astrophysics Data System (ADS)

    Hardisty, D. S.; Lu, Z.; Planavsky, N. J.; Osburn, M. R.; Bekker, A.; Lyons, T. W.

    2013-12-01

    Systematic increases in iodine-to-calcium ratios (I/Ca) in carbonates from both the Precambrian Lomagundi and Shuram carbonate carbon isotope (δ13Ccarb) excursion intervals suggest primary origins for these events. Iodate (IO3-), the oxidized iodine species, is the exclusive species incorporated into carbonates. The high redox sensitivity of IO3- to deoxygenation requires highly oxidizing fluids for IO3- production, making I/Ca in platform carbonates a simple indicator of the presence of oxidizing fluids in the surface ocean. Similarly, redox sensitivity makes the proxy host susceptible to diagenetic iodine loss during carbonate recrystallization in reducing pore fluids. Recent work has shown carbonates to experience near-complete iodine loss during dolomitization in the Permian, and work from our group evaluating modern and recent carbonates demonstrate the potential for diagenetic iodine loss during carbonate recrystallization. In some cases, however, such as meteoric aragonite-to-calcite transitions, oxidizing pore fluids have the potential to buffer IO3- concentrations, causing negligible alteration to primary I/Ca despite negative shifts in δ13Ccarb. These results highlight that diagenetic alterations to I/Ca and δ13Ccarb need not always be coupled, but importantly, no observed scenario promotes post-depositional addition of iodine to carbonates. This means that, independent of δ13Ccarb, systematic, stratigraphic increases in I/Ca ratios observed in the carbonate record are most easily interpreted as resulting from depositional controls such as surface ocean redox or shifts in the total marine iodine reservoir. From this, increasing I/Ca ratios coincident with rising and falling δ13Ccarb trends for the Paleoproterozic Lomagundi and Neoproterozoic Shuram events, respectively, support suggestions of a primary origin for the δ13Ccarb excursions. Significant increase in I/Ca in dolomites deposited during the Lomagundi excursion, rising from blank values in the Archean, suggest very early dolomitization in an oxidizing surface ocean promoting aerobic iodine cycling. This interpretation is consistent with earlier suggestions relating a >+10 ‰ δ13Ccarb shift to substantial organic carbon burial and associated oxygen production. Extremely negative δ13Ccarb (down to <-10 ‰) observed during the Shuram event have been linked to both diagenetic and primary mechanisms. We propose, however, that a marked increase in I/Ca ratios associated with the negative δ13Ccarb excursion in the Khufai Formation of Oman provides evidence for a primary origin for the Shuram. Such an increase could be interpreted as enhanced delivery of IO3- or total iodine from the deep ocean, perhaps driven by deep ocean ventilation and/or oxidation of a large pool of marine-derived organic matter. Overall, regardless of the individual primary controls driving increases in carbonate I/Ca during the Lomagundi and Shuram events, authigenic/diagenetic controls allowing for increased I/Ca are unlikely, suggesting a primary origin for the two largest δ13Ccarb excursions in Earth history.

  15. Potential Cislunar and Interplanetary Proving Ground Excursion Trajectory Concepts

    NASA Technical Reports Server (NTRS)

    McGuire, Melissa L.; Strange, Nathan J.; Burke, Laura M.; MacDonald, Mark A.; McElrath, Timothy P.; Landau, Damon F.; Lantoine, Gregory; Hack, Kurt J.; Lopez, Pedro

    2016-01-01

    NASA has been investigating potential translunar excursion concepts to take place in the 2020s that would be used to test and demonstrate long duration life support and other systems needed for eventual Mars missions in the 2030s. These potential trajectory concepts could be conducted in the proving ground, a region of cislunar and near-Earth interplanetary space where international space agencies could cooperate to develop the technologies needed for interplanetary spaceflight. Enabled by high power Solar Electric Propulsion (SEP) technologies, the excursion trajectory concepts studied are grouped into three classes of increasing distance from the Earth and increasing technical difficulty: the first class of excursion trajectory concepts would represent a 90-120 day round trip trajectory with abort to Earth options throughout the entire length, the second class would be a 180-210 day round trip trajectory with periods in which aborts would not be available, and the third would be a 300-400 day round trip trajectory without aborts for most of the length of the trip. This paper provides a top-level summary of the trajectory and mission design of representative example missions of these three classes of excursion trajectory concepts.

  16. The Carnian (Late Triassic) carbon isotope excursion: new insights from the terrestrial realm

    NASA Astrophysics Data System (ADS)

    Miller, Charlotte; Kürschner, Wolfram; Peterse, Francien; Baranyi, Viktoria; Reichart, Gert-Jan

    2016-04-01

    The geological record contains evidence for numerous pronounced perturbations in the global carbon cycle, some of which are associated with eruptions from large igneous provinces (LIP), and consequently, ocean acidification and mass extinction. In the Carnian (Late Triassic), evidence from sedimentology and fossil pollen points to a significant change in climate, resulting in biotic turnover: during a period termed the 'Carnian Pluvial Event' (CPE). Additionally, during the Carnian, large volumes of flood basalts were erupted from the Wrangellia LIP (western North America). Evidence from the marine realm suggests a fundamental relationship between the CPE, a global 'wet' period, and the injection of light carbon into the atmosphere from the LIP. Here we provide the first evidence from the terrestrial realm of a significant negative δ13C excursion through the CPE recorded in the sedimentary archive of the Wiscombe Park Borehole, Devon (UK). Both total organic matter and plant leaf waxes reflect a gradual carbon isotope excursion of ~-5‰ during this time interval. Our data provides evidence for the global nature of this isotope excursion, supporting the hypothesis that the excursion was likely the result of an injection of light carbon into the atmosphere from the Wrangellia LIP.

  17. Geometrical effects of conventional and digital prosthodontic planning wax-ups on lateral occlusal contact number, contact area, and steepness.

    PubMed

    Abduo, Jaafar

    2017-01-01

    This study evaluated and compared the effect of conventional and digital wax-ups on three lateral occlusion variables: contact number, contact area, and steepness. Dental casts of 10 patients with Angle Class I relationship were included in the study. All patients required fixed prosthodontic treatment that would affect lateral occlusion. The casts of all patients received conventional and digital wax-ups. For pretreatment, conventional wax-up, and digital wax-up casts, contact number, contact area, and occlusion steepness were measured at four lateral positions, that is, at excursions of 0.5, 1.0, 2.0, and 3.0 mm from maximal intercuspation. Lateral occlusion scheme variables were affected by use of diagnostic wax-ups. For all types of casts, contact number decreased as excursion increased. The two types of wax-ups had similar contact number patterns, and contact number was significantly greater for these casts than for pretreatment casts in the earlier stages of excursion. Similarly, contact area gradually decreased with increasing excursion in the pretreatment and conventional and digital wax-up casts. There was only a minimal decrease in occlusion steepness as excursion increased. However, lateral occlusion was generally steeper for digital wax-up casts.

  18. Paleointensity and 40Ar/39Ar geochronology of basalts at Gamarri, Ethiopia: Correlation with the Réunion subchron and Huckleberry Ridge excursion?

    NASA Astrophysics Data System (ADS)

    Kindley, C.; Macho, A.; Tsegaye, M. A.; Feinberg, J. M.; Singer, B. S.; Jicha, B. R.; Brown, M. C.; Birke, T. K.

    2012-12-01

    Characterization of the geomagnetic field during subchrons, reversals, and excursions is vital to understanding geodynamo processes and interactions across the core-mantle boundary. Moreover, an accurate timescale for geomagnetic field instabilities is critical to global high resolution stratigraphy. The Réunion subchron and Huckleberry Ridge excursion are ideal candidates for study due to globally distributed recordings in both sedimentary and igneous rocks. We present new full-vector paleomagnetic data for 30 basaltic flows from the Gamarri volcanic section in the Afar region of Ethiopia and 11 40Ar/39Ar ages. Paleointensities were calculated using the LTD-DHT Shaw technique and results generally agree with those of Carlut et al. (1999). Two geomagnetic instabilities are recorded, an older excursion and a younger period of normal polarity within the reversed Matuyama chron. Our results show a longer duration of low (<20 μT) paleointensity in the oldest flows and more variable low paleointensity values in the younger flows, and are generally lower than Thellier-style values of Carlut et al. (1999). Relative to 28.201 Ma Fish Canyon sanidine, plateau 40Ar/39Ar ages of the youngest (GB21) and oldest (GA02) flows are 2.029 ± 0.041 (2σ) and 2.410 ± 0.130 Ma, respectively. This eruptive duration is longer than that reported by Kidane et al. (1999), where the unspiked K-Ar method yields ages for GB23 (2 flows overlying GB21) and GA02 of 2.02 ± 0.08 (2σ) and 2.14 ± 0.12 Ma, respectively. 40Ar/39Ar ages of 4 lavas within the normal polarity zone in the upper section are between 2.063 ± 0.044 and 2.118 ± 0.057 Ma, but are indistinguishable at 2σ. These flows may sample the Huckleberry Ridge excursion (2.086 ± 0.016 Ma, Singer et al. 2004), the Réunion subchron (2.153-2.115 Ma, Channell et al. 2003), or both. Given several 40Ar/39Ar ages >2.2 Ma, the older excursion in the Gamarri section is not consistent with the Réunion subchron, and can be linked to any of several excursions occurring between ~2.2 and ~2.5 Ma. These excursions have been observed within records from ODP 982 (Channell & Guyodo, 2004) and IODP U1314 (Ohno et al., 2012), as well as within the GPTS as cryptochron C2r.2r-1 (originally dated as 2.420 to 2.441 Ma by Cande & Kent, 1995). Thus, we no longer interpret the excursion recorded in the lower portion of the Gamarri section to be part of the Réunion subchron and recommend that it be omitted from efforts to construct integrated global field models across the Huckleberry Ridge excursion and Réunion subchron.

  19. Evaluation of a new paleosecular variation activity index as a diagnostic tool for geomagnetic field variations

    NASA Astrophysics Data System (ADS)

    Panovska, Sanja; Constable, Catherine

    2015-04-01

    Geomagnetic indices like Dst, K and A, have been used since the early twentieth century to characterize activity in the external part of the modern geomagnetic field and as a diagnostic for space weather. These indices reflect regional and global activity and serve as a proxy for associated physical processes. However, no such tools are yet available for the internal geomagnetic field driven by the geodynamo in Earth's liquid outer core. To some extent this reflects limited spatial and temporal sampling for longer timescales associated with paleomagnetic secular variation, but recent efforts in both paleomagnetic data gathering and modeling activity suggest that longer term characterization of the internal geomagnetic weather/climate and its variability would be useful. Specifically, we propose an index for activity in paleosecular variation, useful as both a local and global measure of field stability during so-called normal secular variation and as a means of identifying more extreme behavior associated with geomagnetic excursions and reversals. To date, geomagnetic excursions have been identified by virtual geomagnetic poles (VGPs) deviating more than some conventional limit from the geographic pole (often 45 degrees), and/or by periods of significant intensity drops below some critical value, for example 50% of the present-day field. We seek to establish a quantitative definition of excursions in paleomagnetic records by searching for synchronous directional deviations and lows in relative paleointensity. We combine paleointensity variations with deviations from the expected geocentric axial dipole (GAD) inclination in a single parameter, which we call the paleosecular variation (PSV) activity index. This new diagnostic can be used on any geomagnetic time series (individual data records, model predictions, spherical harmonic coefficients, etc.) to characterize the level of paleosecular variation activity, find excursions, or even study incipient reversals. Currently reversals can only be detected after they have occurred. A baseline for the new index is established using modern and Holocene geomagnetic field data and models to analyze 'normal' variability. We extend our analyses to the 100 ka interval where several excursions have been identified. We discuss the diminished or absent signatures of excursions in some records, the apparent transgressive behavior of detected excursions, and implications for transitional field behavior. The absence of specific excursions in some sediment records is attributed to smoothing by the sedimentary remanence acquisition process and low sedimentation rates. Overall PSV activity index is inversely correlated with dipole moment, indicating stronger impacts of non-axial-dipole secular variations during periods of low axial dipole strength. Excursional events found with the PSV activity index are analyzed in the context of global probability density functions for VGP positions. We studied the appearance of VGP clusters of the excursions to find the common characteristics of these instabilities, including the non-axial dipole features of the geomagnetic field. A better understanding of geomagnetic excursions will aid attempts to predict when such events might occur in the future.

  20. Paleomagnetic record for the past 80 ka from the Mahanadi basin, Bay of Bengal

    NASA Astrophysics Data System (ADS)

    Usapkar, A.; Dewangan, P.; Mazumdar, A.; Krishna, K. S.; Ramprasad, T.; Badesab, F. K.; Patil, M.; Gaikwad, V. V.

    2018-01-01

    High resolution paleomagnetic investigations were performed on a 50.08 m long sediment core (MD161/20) from Mahanadi basin, Bay of Bengal. Core yielded reliable paleomagnetic results for top 20 m below seafloor (mbsf) which spans about 80 ka. Based on the analysis of rock magnetic data, the core is subdivided into five distinct Zones: Zone 1 and Zone 2 cover top 20 mbsf and do not show any abrupt change in magnetic mineralogy, concentration and grain size. Zones 3 and 5 show significant reduction in χLF, χARM and SIRM due to dissolution of magnetic minerals. Zone 4 shows moderate values of χLF and SIRM. The low value of χARM suggests that magnetic signal is mostly carried by magnetic grains in PSD/MD state. The paleomagnetic data for the top 20 mbsf show four prominent geomagnetic excursions at ∼9 mbsf, ∼13.5 to 15 mbsf, ∼16.3 mbsf and ∼18 to 18.2 mbsf. The age-depth relationship is established using stratigraphic correlation between well-dated sedimentary core NGHP-01-19B and the core MD161/20. The ages of the observed excursions correspond to ∼18 to 20 ka, ∼42 to 49 ka, ∼54 to 57 ka and ∼69 to 70 ka. The excursions at ∼42 to 49 ka, ∼54 to 57 ka, and ∼67 to 70 ka is similar to the known excursions the Laschamp and the split Norwegian-Greenland Sea events (NGS-I and NGS-II). The excursion at 18-20 ka is not observed globally and may be related to lithological/sedimentological changes occurring during last glacial maxima (LGM). The virtual geomagnetic path (VGP) of Laschamp excursion traces clockwise loop. All excursions identified in present study fall in the periods of relatively low paleointensity.

  1. Improved Quaternary North Atlantic stratigraphy using relative paleointensity (RPI), oxygen isotopes, and magnetic excursions (Invited)

    NASA Astrophysics Data System (ADS)

    Channell, J. E.

    2013-12-01

    Improving the resolution of Quaternary marine stratigraphy is one of the major challenges in paleoceanography. IODP Expedition 303/306, and ODP Legs 162 and 172, have yielded multiple high-resolution records (mean sedimentation rates in the 7-20 cm/kyr range) of relative paleointensity (RPI) that are accompanied by oxygen isotope data and extend through much of the Quaternary. Tandem fit of RPI and oxygen isotope data to calibrated templates (LR04 and PISO), using the Match protocol, yields largely consistent stratigraphies, implying that both RPI and oxygen isotope data are dominated by regional/global signals. Based on the recent geomagnetic field, RPI can be expected to be a global signal (i.e. dominated by the axial dipole field) when recorded at sedimentation rates less than several decimeters/kyr. Magnetic susceptibility, on the other hand, is a local/regional lithologic signal, and therefore less useful for long-distance correlation. Magnetic excursions are directional phenomena and, when adequately recorded, are manifest as paired reversals in which the virtual geomagnetic poles (VGPs) reach high latitudes in the opposite hemisphere, and they occupy minima in RPI records. Reversed VGPs imply that excursions are attributable to the main axial dipole, and therefore provide global stratigraphy. The so-called Iceland Basin excursion is recorded at many IODP/ODP sites and lies at the MIS 6/7 boundary at ~188 ka, with a duration of 2-3 kyr. Other excursions in the Brunhes chron are less commonly recorded because their duration (perhaps <~1 kyr) requires sedimentation rates >20 cm/kyr to be adequately recorded. On the other hand, several excursions within the Matuyama Chron are more commonly recorded in North Atlantic drift sediments due to relatively elevated durations. With some notable exceptions (e.g. Iberian Margin), high quality RPI records from North Atlantic sediments, together with magnetic excursions, can be used in tandem with oxygen isotope data to strengthen Quaternary (North Atlantic) stratigraphy.

  2. Volcanic records of the Laschamp geomagnetic excursion from Mt Ruapehu, New Zealand

    NASA Astrophysics Data System (ADS)

    Ingham, E.; Turner, G. M.; Conway, C. E.; Heslop, D.; Roberts, A. P.; Leonard, G.; Townsend, D.; Calvert, A.

    2017-08-01

    We present palaeodirectional records of the Laschamp geomagnetic excursion from lavas on Mt Ruapehu, New Zealand. Fourteen lava flows on the northwestern and southern flanks of Mt Ruapehu, with 40Ar/39Ar weighted mean plateau ages that range from 46.3 ± 2.0 to 39.9 ± 1.4 ka, were studied. The youngest and older flows carry a normal polarity magnetization; however, six flows, dated between 46.3 ± 2.0 and 42.7 ± 1.8 ka, record excursional directions. Three of these flows record southerly palaeomagnetic declinations and negative inclinations that agree well with a published Laschamp record from the Auckland Volcanic Field (AVF). Together, the AVF and Mt Ruapehu lavas currently represent the only volcanic records of the Laschamp excursion outside the Chaîne des Puys region, France. Thus, they make an important contribution to the global set of Laschamp excursion records. Virtual geomagnetic pole (VGP) groups for the New Zealand and French records early in the excursion are compatible with a dipole-dominated field that rotated to an equatorial orientation while simultaneously decaying in strength. In contrast, younger excursional flows from France and New Zealand yield separate VGP groups, which suggest either that the field had a nondipolar morphology in this later phase, or that the VGP groups were not synchronous. 40Ar/39Ar ages for the Mt Ruapehu record are on average slightly older than published northern hemisphere ages and from the relative palaeointensity minimum in the GLOPIS sedimentary stack. Although few individual ages differ significantly at the 2σ level, the spread suggests an overall excursion duration that is longer than the currently accepted 1500 years. This age spread may result from excess Ar in magmas at the time of the eruption biasing the results to slightly older ages, or from non-synchronous excursional field behaviour at near-antipodal locations, or, possibly, a precursory phase prior to the main excursion.

  3. Mono Lake excursion recorded in sediment of the Santa Clara Valley, California

    USGS Publications Warehouse

    Mankinen, Edward A.; Wentworth, Carl M.

    2004-01-01

    Two intervals recording anomalous paleomagnetic inclinations were encountered in the top 40 meters of research drill hole CCOC in the Santa Clara Valley, California. The younger of these two intervals has an age of 28,090 ± 330 radiocarbon years B.P. (calibrated age ∼32.8 ka). This age is in excellent agreement with the latest estimate for the Mono Lake excursion at the type locality and confirms that the excursion has been recorded by sediment in the San Francisco Bay region. The age of an anomalous inclination change below the Mono Lake excursion was not directly determined, but estimates of sedimentation rates indicate that the geomagnetic behavior it represents most likely occurred during the Mono Lake/Laschamp time interval (∼45–28 ka). If true, it may represent one of several recurring fluctuations of magnetic inclination during an interval of a weak geomagnetic dipole, behavior noted in other studies in the region.

  4. Testing the Self-Consistency of the Excursion Set Approach to Predicting the Dark Matter Halo Mass Function

    NASA Astrophysics Data System (ADS)

    Achitouv, I.; Rasera, Y.; Sheth, R. K.; Corasaniti, P. S.

    2013-12-01

    The excursion set approach provides a framework for predicting how the abundance of dark matter halos depends on the initial conditions. A key ingredient of this formalism is the specification of a critical overdensity threshold (barrier) which protohalos must exceed if they are to form virialized halos at a later time. However, to make its predictions, the excursion set approach explicitly averages over all positions in the initial field, rather than the special ones around which halos form, so it is not clear that the barrier has physical motivation or meaning. In this Letter we show that once the statistical assumptions which underlie the excursion set approach are considered a drifting diffusing barrier model does provide a good self-consistent description both of halo abundance as well as of the initial overdensities of the protohalo patches.

  5. Jaw motion during gum-chewing in children with primary dentition.

    PubMed

    Kubota, Naoko; Hayasaki, Haruaki; Saitoh, Issei; Iwase, Yoko; Maruyama, Tomoaki; Inada, Emi; Hasegawa, Hiroko; Yamada, Chiaki; Takemoto, Yoshihiko; Matsumoto, Yuko; Yamasaki, Youichi

    2010-01-01

    This study was undertaken to characterize jaw motion during mastication in children with primary dentition and to compare jaw motion with that in adults. The means and the variances of the traditional parameters for the chewing cycle, i.e., duration, excursive ranges and 3-D distances of travel at the lower incisor, molars and condyles were analyzed and compared in 23 children and 25 female adults. The duration of opening in children was significantly shorter than that of adults. Significant differences between children and adults were observed in lateral and vertical excursion of the incisor, lateral excursion at the molars, and vertical excursion at the condyles. Many of these measurements had larger between-subject and between-cycle variances in children than adults, suggesting that chewing motion in children has not yet matured. The results of this study indicate that chewing motion in children is different from that of adults.

  6. Oxygenation of Ediacaran Ocean recorded by iron isotopes

    NASA Astrophysics Data System (ADS)

    Fan, Haifeng; Zhu, Xiangkun; Wen, Hanjie; Yan, Bin; Li, Jin; Feng, Lianjun

    2014-09-01

    The increase in atmospheric oxygen during the late Neoproterozoic Era (ca. 800-542 Ma) may have stimulated the oxygenation of the deep oceans and the evolution of macroscopic multicellular organisms. However, the mechanism and magnitude of Neoproterozoic oxygenation remain uncertain. We present Fe isotopes, Fe species and other geochemical data for two sections of the Doushantuo Formation (ca. 635-551 Ma) deposited after the Nantuo glacial episode in the Yangtze Gorge area, South China. It is highlighted that highly positive δ56Fe values reflect a lower oxidation rate of Fe(II)aq under ferruginous conditions, and in turn near zero δ56Fe values indicate oxidizing conditions. Our study suggests that during the deposition of the bottom of Member II of the Doushantuo Formation the shallow seawater was oxic, but the deep water was characterized by ferruginous conditions, which is consistent with a redox chemical stratification model. Subsequent anoxic conditions under shallow seawater, represented by positive δ56Fe and negative δ13Ccarb excursions, should be ascribed to the upwelling of Fe(II)aq and dissolved organic carbon (DOC)-rich anoxic deep seawater. The oxidation of Fe (II)aq and DOC-rich anoxic deep seawater upon mixing with oxic shallow water provides an innovative explanation for the well-known negative δ13Ccarb excursions (ENC2) and positive δ56Fe excursions in the middle of Doushantuo Formation. Meanwhile, the upwelling Fe (II)aq- and DOC-rich anoxic deep seawater could increase photosynthetic activity. The balance between oxygen consumption and production was most important criteria for the oxygenation of Early Ediacaran Ocean and diversity of eukaryotic organisms.

  7. The effect of cane use on the compensatory step following posterior perturbations.

    PubMed

    Hall, Courtney D; Jensen, Jody L

    2004-08-01

    The compensatory step is a critical component of the balance response and is impaired in older fallers. The purpose of this research was to examine whether utilization of a cane modified the compensatory step response following external posterior perturbations. Single subject withdrawal design was employed. Single subject statistical analysis--the standard deviation bandwidth-method--supplemented visual analysis of the data. Four older adults (range: 73-83 years) with balance impairment who habitually use a cane completed this study. Subjects received a series of sudden backward pulls that were large enough to elicit compensatory stepping. We examined the following variables both with and without cane use: timing of cane loading relative to step initiation and center of mass acceleration, stability margin, center of mass excursion and velocity, step length and width. No participant loaded the cane prior to initiation of the first compensatory step. There was no effect of cane use on the stability margin, nor was there an effect of cane use on center of mass excursion or velocity, or step length or width. These data suggest that cane use does not necessarily improve balance recovery following an external posterior perturbation when the individual is forced to rely on compensatory stepping. Instead these data suggest that the strongest factor in modifying step characteristics is experience with the perturbation.

  8. HDU Pressurized Excursion Module (PEM) Prototype Systems Integration

    NASA Technical Reports Server (NTRS)

    Gill, Tracy R.; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

    2010-01-01

    The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a skunk-works approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process included establishment of design standards, negotiation of interfaces between subsystems, and scheduling fit checks and installation activities. A major tool used in integration was a coordinated effort to accurately model all the subsystems using CAD, so that conflicts were identified before physical components came together. Some of the major conclusions showed that up-front modularity that emerged as an artifact of construction, such as the eight 45 degree "pie slices" making up the module whose steel rib edges defined structural mounting and loading points, dictated much of the configurational interfaces between the major subsystems and workstations. Therefore, 'one of the lessons learned included the need to use modularity as a tool for organization in advance, and to work harder to prevent non-critical aspects of the platform from dictating the modularity that may eventually inform the fight system.

  9. Load Dependency of Postural Control - Kinematic and Neuromuscular Changes in Response to over and under Load Conditions

    PubMed Central

    Ritzmann, Ramona; Freyler, Kathrin; Weltin, Elmar; Krause, Anne; Gollhofer, Albert

    2015-01-01

    Introduction Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL) and under loading (UL) used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms. Methods Balance performance was recorded under normal loading (NL, 1g), UL (0.16g; 0.38g) and OL (1.8g) in monopedal stance. Center of pressure (COP) displacement and frequency distribution (low 0.15-0.5Hz (LF), medium 0.5-2Hz (MF), high 2-6Hz (HF)) as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios). Results Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL. Conclusion Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal segments to adjust the center of gravity above the base of support. PMID:26053055

  10. Coupled organic and carbonate δ13C records of the late Triassic and early Jurassic in northern Italy: implications for carbon cycling during the aftermath of the end-Triassic mass extinction

    NASA Astrophysics Data System (ADS)

    Bachan, A.; van de Schootbrugge, B.; Payne, J.

    2011-12-01

    A large protracted positive carbon isotope excursion has been observed in the lowermost Jurassic following the end-Triassic mass extinction. However, the lack of paired records from carbonate rocks (δ13Ccarb) and organic carbon (δ13Corg) and limited biostratigraphic constraints leave open the possibility that variations in δ13Ccarb and δ13Corg are not correlative and do not represent a shift in the δ13C of the global carbon pool. Consequently, the long term carbon cycle behavior following the end-Triassic mass extinction remains incompletely understood. Here we present the first extended, coupled δ13Ccarb and δ13Corg records of the uppermost Triassic and lowermost Jurassic from stratigraphic sections in the Lombardy Basin of northern Italy. The large positive excursion previously observed in the carbonates also occurs in the organics from the same samples, but with a smaller magnitude. Because few post-depositional mechanisms affect the isotopic composition of Ccarb and Corg in similar ways, the correspondence of the two curves presents strong support for a primary origin for the large positive isotopic excursion. The more muted response of the organics is consistent with variation in the fractionation between carbonates and organic carbon, mixing of contemporaneous organic matter with extrabasinal organic carbon of a constant isotopic composition, or some combination of the two. In either case, the occurrence of the positive excursion in multiple locations globally in both carbonates and organic matter is best explained by a change in the isotopic value of the global carbon reservoir. The elevated δ13C values and increased magnitude of the difference between the carbonates and organics is consistent with the predicted biogeochemical consequences of heightened pCO2. The coincidence of the extinction and carbon cycle disturbance with emplacement of the Central Atlantic Magmatic Province suggests that volatiles derived from its emplacement were the likely source of the perturbation.

  11. Aptian Carbon Isotope Stratigraphy in Sierra del Rosario, Northeastern Mexico

    NASA Astrophysics Data System (ADS)

    Barragan-Manzo, R.; Moreno-Bedmar, J.; Nuñez, F.; Company, M.

    2013-05-01

    In most recent years Aptian carbon isotope stratigraphy has been widely studied in Europe where isotopic stages have been developed to correlate global events. Two negative excursions have been recorded in the Lower Aptian, the older is OAE 1a in the middle part, and a younger negative excursion labeled "Aparein level", which occurs in the uppermost part of the Lower Aptian. In Mexico previous works reported a carbon isotope negative excursion in the lowermost part of the La Peña Formation that was assigned to the onset of Oceanic Anoxic Event 1a (=OAE 1a). In this work we study the isotopic record of the δ13Ccarb of 32 bulk rock samples of limestone from the uppermost part of the Cupido Formation and the lower part of the La Peña Formation at the Francisco Zarco Dam Section (=FZD), Durango State, northeastern Mexico. The isotopic data are calibrated using the latest ammonite biostratigraphic biozonation of the Aptian. This age calibration allows us to make a precise correlation between the carbon isotopic record of Mexico and several European sections (e.g. Spain and France). In the studied Francisco Zarco Dam section we recognize a negative carbon isotopic excursion in the Dufrenoyia justinae ammonite Zone that corresponds to the "Aparein level", which we correlate using the ammonite zonation of others European sections (Figure 1). This correlation allows us to see how the negative excursion that characterizes the "Aparein level" is consistent with the C7 segment. Thus, our recent stratigraphic study allows us to conclude that the ammonite record in the lowermost part of the La Peña Formation is regionally isochronous, and correlates with the Dufrenoyia justinae Zone and Lower Aptian isotope interval C7. In agreement to these biostratigraphic data, the supposed record of the OAE 1a in the lowermost part of the La Peña Formation is not correct, and the carbon isotope negative excursion must be assigned to the younger event "Aparein level". Taking this into account, other Lower Aptian negative excursions reported in the literature and assigned to the OAE 1a, perhaps, must be reconsidered to distinguish among the two Lower Aptian negative excursions.; Figure 1: Isotopic curve of the FZD section compared with one section of Spain. The sharp negative peak in the Mexican section is compared with the Spanish section (see the arrow).

  12. From the Law of Large Numbers to Large Deviation Theory in Statistical Physics: An Introduction

    NASA Astrophysics Data System (ADS)

    Cecconi, Fabio; Cencini, Massimo; Puglisi, Andrea; Vergni, Davide; Vulpiani, Angelo

    This contribution aims at introducing the topics of this book. We start with a brief historical excursion on the developments from the law of large numbers to the central limit theorem and large deviations theory. The same topics are then presented using the language of probability theory. Finally, some applications of large deviations theory in physics are briefly discussed through examples taken from statistical mechanics, dynamical and disordered systems.

  13. Growth of Interfacial Intermetallic Compound Layer in Diffusion-Bonded SAC-Cu Solder Joints During Different Types of Thermomechanical Excursion

    NASA Astrophysics Data System (ADS)

    Kanjilal, Anwesha; Kumar, Praveen

    2018-01-01

    The effects of mechanical strain on the growth kinetics of interfacial intermetallic compounds (IMCs) sandwiched between Cu substrate and Sn-1.0 wt.%Ag-0.5 wt.%Cu (SAC105) solder have been investigated. Isothermal aging (IA) at 70°C and 125°C, and thermal cycling (TC) as well as thermomechanical cycling (TMC) with shear strain of 12.8% per cycle between -25°C and 125°C were applied to diffusion-bonded solder joints to study the growth behavior of the interfacial IMC layer under various types of thermomechanical excursion (TME). The microstructure of the solder joint tested under each TME was observed at regular intervals. It was observed that the growth rate of the IMC layer was higher in the case of TMC compared with TC or IA. This increased growth rate of the IMC layer in the presence of mechanical strain suggests an additional driving force that enhances the growth kinetics of the IMC. Finite element analysis was performed to gain insight into the effect of TC and TMC on the stress field in the solder joint, especially near the interface between the solder and the substrate. Finally, an analytical model was developed to quantify the effect of strain on the effective diffusivity and express the growth kinetics for all three types of TME using a single expression.

  14. Evidence for a rapid release of carbon at the Paleocene-Eocene thermal maximum.

    PubMed

    Wright, James D; Schaller, Morgan F

    2013-10-01

    The Paleocene/Eocene thermal maximum (PETM) and associated carbon isotope excursion (CIE) are often touted as the best geologic analog for the current anthropogenic rise in pCO2. However, a causal mechanism for the PETM CIE remains unidentified because of large uncertainties in the duration of the CIE's onset. Here, we report on a sequence of rhythmic sedimentary couplets comprising the Paleocene/Eocene Marlboro Clay (Salisbury Embayment). These couplets have corresponding δ(18)O cycles that imply a climatic origin. Seasonal insolation is the only regular climate cycle that can plausibly account for δ(18)O amplitudes and layer counts. High-resolution stable isotope records show 3.5‰ δ(13)C decrease over 13 couplets defining the CIE onset, which requires a large, instantaneous release of (13)C-depleted carbon. During the CIE, a clear δ(13)C gradient developed on the shelf with the largest excursions in shallowest waters, indicating atmospheric δ(13)C decreased by ~20‰. Our observations and revised release rate are consistent with an atmospheric perturbation of 3,000-gigatons of carbon (GtC).

  15. Evidence for a rapid release of carbon at the Paleocene-Eocene thermal maximum

    PubMed Central

    Wright, James D.; Schaller, Morgan F.

    2013-01-01

    The Paleocene/Eocene thermal maximum (PETM) and associated carbon isotope excursion (CIE) are often touted as the best geologic analog for the current anthropogenic rise in pCO2. However, a causal mechanism for the PETM CIE remains unidentified because of large uncertainties in the duration of the CIE’s onset. Here, we report on a sequence of rhythmic sedimentary couplets comprising the Paleocene/Eocene Marlboro Clay (Salisbury Embayment). These couplets have corresponding δ18O cycles that imply a climatic origin. Seasonal insolation is the only regular climate cycle that can plausibly account for δ18O amplitudes and layer counts. High-resolution stable isotope records show 3.5‰ δ13C decrease over 13 couplets defining the CIE onset, which requires a large, instantaneous release of 13C-depleted carbon. During the CIE, a clear δ13C gradient developed on the shelf with the largest excursions in shallowest waters, indicating atmospheric δ13C decreased by ∼20‰. Our observations and revised release rate are consistent with an atmospheric perturbation of 3,000-gigatons of carbon (GtC). PMID:24043840

  16. Single versus successive pop-in modes in nanoindentation tests of single crystals

    DOE PAGES

    Xia, Yuzhi; Gao, Yanfei; Pharr, George M.; ...

    2016-05-24

    From recent nanoindentation experiments, two types of pop-in modes have been identified: a single pop-in with a large displacement excursion, or a number of pop-ins with comparable and small displacement excursions. Theoretical analyses are developed here to study the roles played by indenter tip radius, pre-existing defect density, heterogeneous nucleation source type, and lattice resistance on the pop-in modes. The evolution of dislocation structures in earlier pop-ins provides input to modeling a stochastic, heterogeneous mechanism that may be responsible for the subsequent pop-ins. It is found that when the first pop-in occurs near theoretical shear stress, the pop-in mode ismore » determined by the lattice resistance and tip radius. When the first pop-in occurs at low shear stress, whether the successive pop-in mode occurs depends on how the heterogeneous dislocation nucleation source density increases as compared to the increase of the total dislocation density. Lastly, the above transitions are found to correlate well with the ratio of indenter tip radius to the mean spacing of dislocation nucleation sources.« less

  17. Paleomagnetic record determined in cores from deep research wells in the Quaternary Santa Clara basin, California

    USGS Publications Warehouse

    Mankinen, Edward A.; Wentworth, Carl M.

    2016-01-01

    The Mono Lake (ca. 32 ka), Pringle Falls (ca. 210 ka), and Big Lost (ca. 565 ka) geomagnetic excursions all seem to be represented in the Santa Clara Valley wells. Possible correlations to the Laschamp (ca. 40 ka) and Blake (ca. 110 ka) excursions are also noted. Three additional excursions that have apparently not been previously reported from western North America occur within cycle 6 (between 536 and 433 ka), near the base of cycle 5 (after 433 ka), and near the middle of cycle 2 (before ca. 75 ka).

  18. Scaling fixed-field alternating gradient accelerators with a small orbit excursion.

    PubMed

    Machida, Shinji

    2009-10-16

    A novel scaling type of fixed-field alternating gradient (FFAG) accelerator is proposed that solves the major problems of conventional scaling and nonscaling types. This scaling FFAG accelerator can achieve a much smaller orbit excursion by taking a larger field index k. A triplet focusing structure makes it possible to set the operating point in the second stability region of Hill's equation with a reasonable sensitivity to various errors. The orbit excursion is about 5 times smaller than in a conventional scaling FFAG accelerator and the beam size growth due to typical errors is at most 10%.

  19. Earth's magnetic field is probably not reversing.

    PubMed

    Brown, Maxwell; Korte, Monika; Holme, Richard; Wardinski, Ingo; Gunnarson, Sydney

    2018-05-15

    The geomagnetic field has been decaying at a rate of ∼5% per century from at least 1840, with indirect observations suggesting a decay since 1600 or even earlier. This has led to the assertion that the geomagnetic field may be undergoing a reversal or an excursion. We have derived a model of the geomagnetic field spanning 30-50 ka, constructed to study the behavior of the two most recent excursions: the Laschamp and Mono Lake, centered at 41 and 34 ka, respectively. Here, we show that neither excursion demonstrates field evolution similar to current changes in the geomagnetic field. At earlier times, centered at 49 and 46 ka, the field is comparable to today's field, with an intensity structure similar to today's South Atlantic Anomaly (SAA); however, neither of these SAA-like fields develop into an excursion or reversal. This suggests that the current weakened field will also recover without an extreme event such as an excursion or reversal. The SAA-like field structure at 46 ka appears to be coeval with published increases in geomagnetically modulated beryllium and chlorine nuclide production, despite the global dipole field not weakening significantly in our model during this time. This agreement suggests a greater complexity in the relationship between cosmogenic nuclide production and the geomagnetic field than is commonly assumed.

  20. Predicted torque equilibrium attitude utilization for Space Station attitude control

    NASA Technical Reports Server (NTRS)

    Kumar, Renjith R.; Heck, Michael L.; Robertson, Brent P.

    1990-01-01

    An approximate knowledge of the torque equilibrium attitude (TEA) is shown to improve the performance of a control moment gyroscope (CMG) momentum management/attitude control law for Space Station Freedom. The linearized equations of motion are used in conjunction with a state transformation to obtain a control law which uses full state feedback and the predicted TEA to minimize both attitude excursions and CMG peak and secular momentum. The TEA can be computationally determined either by observing the steady state attitude of a 'controlled' spacecraft using arbitrary initial attitude, or by simulating a fixed attitude spacecraft flying in desired orbit subject to realistic environmental disturbance models.

  1. Young Athletes With Quadriceps Femoris Strength Asymmetry at Return to Sport After Anterior Cruciate Ligament Reconstruction Demonstrate Asymmetric Single-Leg Drop-Landing Mechanics.

    PubMed

    Ithurburn, Matthew P; Paterno, Mark V; Ford, Kevin R; Hewett, Timothy E; Schmitt, Laura C

    2015-11-01

    Young athletes who have had anterior cruciate ligament (ACL) reconstruction demonstrate suboptimal rates of return to sport, high rates of second ACL injuries, and persistent movement asymmetries. Therefore, the influence of musculoskeletal impairments on movement mechanics in this population needs to be further evaluated. The primary hypothesis was that among young athletes who have had ACL reconstruction, those with greater quadriceps strength asymmetry would demonstrate altered single-leg drop-landing mechanics at return to sport compared with individuals with more symmetric quadriceps strength and also compared with healthy controls (ie, those with no ACL reconstruction). A second hypothesis was that quadriceps strength symmetry would predict single-leg drop-landing symmetry in individuals who have undergone ACL reconstruction. Controlled laboratory study. The study entailed a total of 103 participants (age, 17.4 years) at the time of return to sport after ACL reconstruction and 47 control participants (age, 17.0 years). The quadriceps index (QI) was calculated for isometric quadriceps strength, which was then used to divide the ACL reconstruction participants into high-quadriceps (QI ≥90%; n = 52) and low-quadriceps (QI <85%; n = 41) subgroups. Biomechanical data were collected by use of 3-dimensional motion analysis during a single-leg drop-landing task. The LSI was calculated for kinematic and kinetic sagittal-plane variables of interest during landing. Group differences were compared by use of 1-way analysis of variance and linear regression analyses (α < .05). Both the low- and high-quadriceps groups demonstrated greater limb asymmetry during landing compared with the control group in knee flexion excursion (mean LSI ± SD: low quadriceps, 85.8% ± 15.5% [P < .001]; high quadriceps, 94.2% ± 15.6% [P = .019]; control, 102.7% ± 14.1%), peak trunk flexion angle (low quadriceps, 129.2% ± 36.6% [P < .001]; high quadriceps, 110.5% ± 22.6% [P = .03]; control, 95.5% ± 26.2%), and peak knee extension moment (low quadriceps, 79.5% ± 25.2% [P < .001]; high quadriceps, 89.9% ± 19.8% [P = .005]; control, 102.2% ± 10.9%). Compared with the high-quadriceps group, the low-quadriceps group also demonstrated greater asymmetry during landing in knee flexion excursion (P = .026), peak trunk flexion angle (P = .006), and peak knee extension moment (P = .034). In the ACL reconstruction group, quadriceps strength symmetry predicted symmetry in knee flexion excursion, peak trunk flexion, and peak knee extension moment (all P < .001) and predicted symmetry in peak trunk flexion angle (P < .001) after controlling for graft type, knee-related pain, function with activities of daily living, and sport function. At the time of return to sport, athletes who had undergone ACL reconstruction, including those in both the high- and low-quadriceps groups, demonstrated asymmetry during a single-leg drop-landing task compared with controls. Compensations included increased trunk flexion, decreased knee flexion excursion, and decreased knee extension moments on the involved limb. In addition, individuals in the low-quadriceps group demonstrated greater movement asymmetry compared with individuals in the high-quadriceps group. Restoration of symmetric quadriceps strength after ACL reconstruction is associated with more symmetric mechanics during a single-leg drop-landing movement. However, this appears to be multifactorial, as the high-quadriceps group also demonstrated landing asymmetries. Restoration of symmetric quadriceps strength may improve postoperative athletic participation; however, future study is warranted. © 2015 The Author(s).

  2. Biology Excursions

    ERIC Educational Resources Information Center

    Baldock, R. N.

    1973-01-01

    Provides many useful suggestions and cautions for planning and executing a biology field excursion. Specific procedures are outlined for investigating land communities and coastal areas, and a number of follow-up laboratory activities are described. The appendix provides an extensive bibliography with useful comments on the literature. (JR)

  3. Influence of dietary protein on postprandial blood glucose levels in individuals with Type 1 diabetes mellitus using intensive insulin therapy.

    PubMed

    Paterson, M A; Smart, C E M; Lopez, P E; McElduff, P; Attia, J; Morbey, C; King, B R

    2016-05-01

    To determine the effects of protein alone (independent of fat and carbohydrate) on postprandial glycaemia in individuals with Type 1 diabetes mellitus using intensive insulin therapy. Participants with Type 1 diabetes mellitus aged 7-40 years consumed six 150 ml whey isolate protein drinks [0 g (control), 12.5, 25, 50, 75 and 100] and two 150 ml glucose drinks (10 and 20 g) without insulin, in randomized order over 8 days, 4 h after the evening meal. Continuous glucose monitoring was used to assess postprandial glycaemia. Data were collected from 27 participants. Protein loads of 12.5 and 50 g did not result in significant postprandial glycaemic excursions compared with control (water) throughout the 300 min study period (P > 0.05). Protein loads of 75 and 100 g resulted in lower glycaemic excursions than control in the 60-120 min postprandial interval, but higher excursions in the 180-300 min interval. In comparison with 20 g glucose, the large protein loads resulted in significantly delayed and sustained glucose excursions, commencing at 180 min and continuing to 5 h. Seventy-five grams or more of protein alone significantly increases postprandial glycaemia from 3 to 5 h in people with Type 1 diabetes mellitus using intensive insulin therapy. The glycaemic profiles resulting from high protein loads differ significantly from the excursion from glucose in terms of time to peak glucose and duration of the glycaemic excursion. This research supports recommendations for insulin dosing for large amounts of protein. © 2015 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

  4. The Record of Geomagnetic Excursions from a ~150 m Sediment Core: Clear Lake, Northern California

    NASA Astrophysics Data System (ADS)

    Levin, E.; Byrne, R.; Looy, C. V.; Wahl, D.; Noren, A. J.; Verosub, K. L.

    2015-12-01

    We are studying the paleomagnetic properties of a new ~150 meter drill core from Clear Lake, CA. Step-wise demagnetization of the natural remanent magnetism (NRM) yields stable directions after 20 mT, implying that the sediments are reliable recorders of geomagnetic field behavior. Several intervals of low relative paleointensity (RPI) from the core appear to be correlated with known geomagnetic excursions. At about 46 m depth, and ~33 ka according to an age model based on radiocarbon dates obtained from pollen and the Olema ash bed, a low RPI zone seems to agree with the age and duration of the Mono Lake Excursion, previously identified between 32 and 35 ka. Slightly lower in the core, at about 50 m depth and ~40 ka, noticeably low RPI values seem to be coeval with the Laschamp excursion, which has been dated at ~41 ka. A volcanic ash near the bottom of the core (141 mblf) is near the same depth as an ash identified in 1988 by Andrei Sarna-Wojcicki and others as the Loleta ash bed in a previous Clear Lake core. If the basal ash in the new core is indeed the, Loleta ash bed, then the core may date back to about 270-300 ka. Depending on the age of the lowest ash, a sequence of low RPI intervals could correlate with the Blake (120 ka), Iceland Basin (188 ka), Jamaica/Pringle Falls (211 ka), and CR0 (260 ka) excursions. Correlation of the low RPI intervals to these geomagnetic excursions will help in the development of a higher resolution chronostratigraphy for the core, resolve a long-standing controversy about a possible hiatus in the Clear Lake record, and provide information about climatically-driven changes in sedimentation.

  5. Antecedent Synoptic Environments Conducive to North American Polar/Subtropical Jet Superpositions

    NASA Astrophysics Data System (ADS)

    Winters, A. C.; Keyser, D.; Bosart, L. F.

    2017-12-01

    The atmosphere often exhibits a three-step pole-to-equator tropopause structure, with each break in the tropopause associated with a jet stream. The polar jet stream (PJ) typically resides in the break between the polar and subtropical tropopause and is positioned atop the strongly baroclinic, tropospheric-deep polar front around 50°N. The subtropical jet stream (STJ) resides in the break between the subtropical and the tropical tropopause and is situated on the poleward edge of the Hadley cell around 30°N. On occasion, the latitudinal separation between the PJ and the STJ can vanish, resulting in a vertical jet superposition. Prior case study work indicates that jet superpositions are often attended by a vigorous transverse vertical circulation that can directly impact the production of extreme weather over North America. Furthermore, this work suggests that there is considerable variability among antecedent environments conducive to the production of jet superpositions. These considerations motivate a comprehensive study to examine the synoptic-dynamic mechanisms that operate within the double-jet environment to produce North American jet superpositions. This study focuses on the identification of North American jet superposition events in the CFSR dataset during November-March 1979-2010. Superposition events will be classified into three characteristic types: "Polar Dominant" events will consist of events during which only the PJ is characterized by a substantial excursion from its climatological latitude band; "Subtropical Dominant" events will consist of events during which only the STJ is characterized by a substantial excursion from its climatological latitude band; and "Hybrid" events will consist of those events characterized by an excursion of both the PJ and STJ from their climatological latitude bands. Following their classification, frequency distributions of jet superpositions will be constructed to highlight the geographical locations most often associated with jet superpositions for each event type. PV inversion and composite analysis will also be performed on each event type in an effort to illustrate the antecedent environments and the dominant synoptic-dynamic mechanisms that favor the production of North American jet superpositions for each event type.

  6. Speckle tracking as a method to measure hemidiaphragm excursion.

    PubMed

    Goutman, Stephen A; Hamilton, James D; Swihart, Blake; Foerster, Bradley; Feldman, Eva L; Rubin, Jonathan M

    2017-01-01

    Diaphragm excursion measured via ultrasound may be an important imaging outcome measure of respiratory function. We developed a new method for measuring diaphragm movement and compared it to the more traditional M-mode method. Ultrasound images of the right and left hemidiaphragms were collected to compare speckle tracking and M-mode measurements of diaphragm excursion. Speckle tracking was performed using EchoInsight (Epsilon Imaging, Ann Arbor, Michigan). Six healthy subjects without a history of pulmonary diseases were included in this proof-of-concept study. Speckle tracking of the diaphragm is technically possible. Unlike M-mode, speckle tracking carries the advantage of reliable visualization and measurement of the left hemidiaphragm. Speckle tracking accounted for diaphragm movement simultaneously in the cephalocaudad and mediolateral directions, unlike M-mode, which is 1-dimensional. Diaphragm speckle tracking may represent a novel, more robust method for measuring diaphragm excursion, especially for the left hemidiaphragm. Muscle Nerve 55: 125-127, 2017. © 2016 Wiley Periodicals, Inc.

  7. Effects of numerical dissipation and unphysical excursions on scalar-mixing estimates in large-eddy simulations

    NASA Astrophysics Data System (ADS)

    Sharan, Nek; Matheou, Georgios; Dimotakis, Paul

    2017-11-01

    Artificial numerical dissipation decreases dispersive oscillations and can play a key role in mitigating unphysical scalar excursions in large eddy simulations (LES). Its influence on scalar mixing can be assessed through the resolved-scale scalar, Z , its probability density function (PDF), variance, spectra, and the budget of the horizontally averaged equation for Z2. LES of incompressible temporally evolving shear flow enabled us to study the influence of numerical dissipation on unphysical scalar excursions and mixing estimates. Flows with different mixing behavior, with both marching and non-marching scalar PDFs, are studied. Scalar fields for each flow are compared for different grid resolutions and numerical scalar-convection term schemes. As expected, increasing numerical dissipation enhances scalar mixing in the development stage of shear flow characterized by organized large-scale pairings with a non-marching PDF, but has little influence in the self-similar stage of flows with marching PDFs. Flow parameters and regimes sensitive to numerical dissipation help identify approaches to mitigate unphysical excursions while minimizing dissipation.

  8. Geomagnetic paleointensities from excursion sequences in lavas on Oahu, Hawaii

    USGS Publications Warehouse

    Coe, Robert S.; Gromme, Sherman; Mankinen, Edward A.

    1984-01-01

    Paleomagnetic data demonstrating three late Tertiary excursions in the direction of the geomagnetic field recorded in sequences of basaltic lavas on the island of Oahu, Hawaii were published by R. R. Doell and G. B. Dalrymple in 1973. We have determined geomagnetic paleointensities by the Thelliers' method for 14 lavas from the three sites. During these experiments, considerable difficulty was encountered because of the presence of titanomaghemite in many lavas and the contamination of natural remanent magnetization by lightning in many others. Moreover, we often observed the production of spurious high‐temperature chemical remanent magnetization during the Thellier experiments. An analysis of this particularly troublesome problem is presented. Two of the sites showed low paleointensities associated with angular departures of the paleomagnetic field direction from that of a geocentric axial dipole, which suggests that these excursions represent aborted reversals or fragments of reversals. At the third site, however, the paleointensity did not become low as the field diverged. This excursion may reflect the variation of a large nondipole source near Hawaii.

  9. Illness and injury to students on a school excursion to Peru.

    PubMed

    Shaw, Marc T M; Harding, Elizabeth; Leggat, Peter A

    2014-01-01

    School-organized travels abroad provide an opportunity for students to undertake supervised travel that reinforces scholastic study of various geographical locations under the direction and protection of experienced tour leaders and health professional support. Little is known concerning the nature of illnesses and injuries occurring on overseas school excursions. This study was designed to investigate the prevalence of injury and illness suffered by older teenagers on a school excursion to South America. In 2010, the school's tour physician (EH) diagnosed and recorded all illnesses and injuries among 29 school girls and 6 accompanying adults on a school excursion to Peru. Information recorded included age, sex, the nature of the presenting illness, number of days into the tour, the assessment of the condition, and the treatment employed during the excursion's field phase of 21 days. A total of 32 (91%) travelers sought medical advice at least once for a total of 371 consultations, resulting in 153 separate diagnoses. The mean age of the students was 16 years with six adults accompanying the students being significantly older. Primary illnesses diagnosed were related to the following systems and conditions: gastrointestinal (58, 37%), respiratory (25, 16%), altitude sickness (19, 12%), genitourinary (8, 5%), dermatological (10, 7%), trauma (7, 5%), neurological (7, 5%), anxiety or psychological adjustment (7, 5%), adverse drug reactions (4, 3%), and musculoskeletal (5, 3%). The most commonly used medications were antidiarrheal and antiemetic medication. There were six accidents during the journey resulting in minor soft-tissue injuries. There were no deaths or other major accidents requiring emergency evacuation or hospitalization. On this school excursion, the health problems encountered were consistent with those reported for other specialized tours, including expeditions and premium tours, although altitude illness needs to be carefully planned for in tours to higher elevation destinations as in South America. As well as being part of the service provided to the school students, the inclusion of a physician with appropriate medical supplies for this tour increased the independence of the travel group. A proposed medical kit for such an excursion is presented. © 2014 International Society of Travel Medicine.

  10. Occupant kinematics in low-speed frontal sled tests: Human volunteers, Hybrid III ATD, and PMHS.

    PubMed

    Beeman, Stephanie M; Kemper, Andrew R; Madigan, Michael L; Franck, Christopher T; Loftus, Stephen C

    2012-07-01

    A total of 34 dynamic matched frontal sled tests were performed, 17 low (2.5g, Δv=4.8kph) and 17 medium (5.0g, Δv=9.7kph), with five male human volunteers of approximately 50th percentile height and weight, a Hybrid III 50th percentile male ATD, and three male PMHS. Each volunteer was exposed to two impulses at each severity, one relaxed and one braced prior to the impulse. A total of four tests were performed at each severity with the ATD and one trial was performed at each severity with each PMHS. A Vicon motion analysis system, 12 MX-T20 2 megapixel cameras, was used to quantify subject 3D kinematics (±1mm) (1kHz). Excursions of select anatomical regions were normalized to their respective initial positions and compared by test condition and between subject types. The forward excursions of the select anatomical regions generally increased with increasing severity. The forward excursions of relaxed human volunteers were significantly larger than those of the ATD for nearly every region at both severities. The forward excursions of the upper body regions of the braced volunteers were generally significantly smaller than those of the ATD at both severities. Forward excursions of the relaxed human volunteers and PMHSs were fairly similar except the head CG response at both severities and the right knee and C7 at the medium severity. The forward excursions of the upper body of the PMHS were generally significantly larger than those of the braced volunteers at both severities. Forward excursions of the PMHSs exceeded those of the ATD for all regions at both severities with significant differences within the upper body regions. Overall human volunteers, ATD, and PMHSs do not have identical biomechanical responses in low-speed frontal sled tests but all contribute valuable data that can be used to refine and validate computational models and ATDs used to assess injury risk in automotive collisions. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Determining the Accuracy of Paleomagnetic Remanence and High-Resolution Chronostratigraphy for Sedimentary Rocks using Rock Magnetics

    NASA Astrophysics Data System (ADS)

    Kodama, K. P.

    2017-12-01

    The talk will consider two broad topics in rock magnetism and paleomagnetism: the accuracy of paleomagnetic remanence and the use of rock magnetics to measure geologic time in sedimentary sequences. The accuracy of the inclination recorded by sedimentary rocks is crucial to paleogeographic reconstructions. Laboratory compaction experiments show that inclination shallows on the order of 10˚-15˚. Corrections to the inclination can be made using the effects of compaction on the directional distribution of secular variation recorded by sediments or the anisotropy of the magnetic grains carrying the ancient remanence. A summary of all the compaction correction studies as of 2012 shows that 85% of sedimentary rocks studied have enjoyed some amount of inclination shallowing. Future work should also consider the effect of grain-scale strain on paleomagnetic remanence. High resolution chronostratigraphy can be assigned to a sedimentary sequence using rock magnetics to detect astronomically-forced climate cycles. The power of the technique is relatively quick, non-destructive measurements, the objective identification of the cycles compared to facies interpretations, and the sensitivity of rock magnetics to subtle changes in sedimentary source. An example of this technique comes from using rock magnetics to identify astronomically-forced climate cycles in three globally distributed occurrences of the Shuram carbon isotope excursion. The Shuram excursion may record the oxidation of the world ocean in the Ediacaran, just before the Cambrian explosion of metazoans. Using rock magnetic cyclostratigraphy, the excursion is shown to have the same duration (8-9 Myr) in southern California, south China and south Australia. Magnetostratigraphy of the rocks carrying the excursion in California and Australia shows a reversed to normal geomagnetic field polarity transition at the excursion's nadir, thus supporting the synchroneity of the excursion globally. Both results point to a primary depositional origin for the excursion, and strengthens the argument for oxidation of the world ocean in the Ediacaran. Future work must learn how global climate is encoded by rock magnetics, but our work to date suggests that variations in continental run-off are detected by rock magnetics.

  12. Invariance in the recurrence of large returns and the validation of models of price dynamics

    NASA Astrophysics Data System (ADS)

    Chang, Lo-Bin; Geman, Stuart; Hsieh, Fushing; Hwang, Chii-Ruey

    2013-08-01

    Starting from a robust, nonparametric definition of large returns (“excursions”), we study the statistics of their occurrences, focusing on the recurrence process. The empirical waiting-time distribution between excursions is remarkably invariant to year, stock, and scale (return interval). This invariance is related to self-similarity of the marginal distributions of returns, but the excursion waiting-time distribution is a function of the entire return process and not just its univariate probabilities. Generalized autoregressive conditional heteroskedasticity (GARCH) models, market-time transformations based on volume or trades, and generalized (Lévy) random-walk models all fail to fit the statistical structure of excursions.

  13. Immediate Effects of a Single Session of Motor Skill Training on the Lumbar Movement Pattern During a Functional Activity in People With Low Back Pain: A Repeated-Measures Study.

    PubMed

    Marich, Andrej V; Lanier, Vanessa M; Salsich, Gretchen B; Lang, Catherine E; Van Dillen, Linda R

    2018-04-06

    People with low back pain (LBP) may display an altered lumbar movement pattern of early lumbar motion compared to people with healthy backs. Modifying this movement pattern during a clinical test decreases pain. It is unknown whether similar effects would be seen during a functional activity. The objective of this study is was to examine the lumbar movement patterns before and after motor skill training, effects on pain, and characteristics that influenced the ability to modify movement patterns. The design consisted of a repeated-measures study examining early-phase lumbar excursion in people with LBP during a functional activity test. Twenty-six people with chronic LBP received motor skill training, and 16 people with healthy backs were recruited as a reference standard. Twenty minutes of motor skill training to decrease early-phase lumbar excursion during the performance of a functional activity were used as a treatment intervention. Early-phase lumbar excursion was measured before and after training. Participants verbally reported increased pain, decreased pain, or no change in pain during performance of the functional activity test movement in relation to their baseline pain. The characteristics of people with LBP that influenced the ability to decrease early-phase lumbar excursion were examined. People with LBP displayed greater early-phase lumbar excursion before training than people with healthy backs (LBP: mean = 11.2°, 95% CI = 9.3°-13.1°; healthy backs: mean = 7.1°, 95% CI = 5.8°-8.4°). Following training, the LBP group showed a decrease in the amount of early-phase lumbar excursion (mean change = 4.1°, 95% CI = 2.4°-5.8°); 91% of people with LBP reported that their pain decreased from baseline following training. The longer the duration of LBP (β = - 0.22) and the more early-phase lumbar excursion before training (β = - 0.82), the greater the change in early-phase lumbar excursion following training. The long-term implications of modifying the movement pattern and whether the decrease in pain attained was clinically significant are unknown. People with LBP were able to modify their lumbar movement pattern and decrease their pain with the movement pattern within a single session of motor skill training.

  14. Engaging students in research learning experiences through hydrology field excursions and short films

    NASA Astrophysics Data System (ADS)

    Ewen, Tracy; Seibert, Jan

    2015-04-01

    One of the best ways to engage students and instill enthusiasm for hydrology is to expose them to hands-on learning. A focus on hydrology field research can be used to develop context-rich and active learning, and help solidify idealized learning where students are introduced to individual processes through textbook examples, often neglecting process interactions and an appreciation for the complexity of the system. We introduced a field course where hydrological measurement techniques are used to study processes such as snow hydrology and runoff generation, while also introducing students to field research and design of their own field project. Additionally, we produced short films of each of these research-based field excursions, with in-house film expertise. These films present a short overview of field methods applied in alpine regions and will be used for our larger introductory hydrology courses, exposing students to field research at an early stage, and for outreach activities, including for potential high school students curious about hydrology. In the field course, students design a low-budget experiment with the aim of going through the different steps of a 'real' scientific project, from formulating the research question to presenting their results. During the field excursions, students make discharge measurements in several alpine streams with a salt tracer to better understand the spatial characteristics of an alpine catchment, where source waters originate and how they contribute to runoff generation. Soil moisture measurements taken by students in this field excursion were used to analyze spatial soil moisture patterns in the alpine catchment and subsequently used in a publication. Another field excursion repeats a published experiment, where preferential soil flow paths are studied using a tracer and compared to previously collected data. For each field excursion, observational data collected by the students is uploaded to an online database we developed, where students can also retrieve data from past excursions to further analyze and compare their data. At each of the field sites, weather stations were installed and a webviewer allows access to realtime data from data loggers, allowing students to explore how processes relate to climatic conditions. Together, these field excursions give students the necessary tools they will need to carry out field research of their own in future projects, whether in academia or industry, while the short films give potential or first-year students an impression of what hydrology is all about and hopefully inspire them to become future hydrologists.

  15. A gaussian model for simulated geomagnetic field reversals

    NASA Astrophysics Data System (ADS)

    Wicht, Johannes; Meduri, Domenico G.

    2016-10-01

    Field reversals are the most spectacular events in the geomagnetic history but remain little understood. Here we explore the dipole behaviour in particularly long numerical dynamo simulations to reveal statistically significant conditions required for reversals and excursions to happen. We find that changes in the axial dipole moment behaviour are crucial while the equatorial dipole moment plays a negligible role. For small Rayleigh numbers, the axial dipole always remains strong and stable and obeys a clearly Gaussian probability distribution. Only when the Rayleigh number is increased sufficiently the axial dipole can reverse and its distribution becomes decisively non-Gaussian. Increased likelihoods around zero indicate a pronounced lingering in a new low dipole moment state. Reversals and excursions can only happen when axial dipole fluctuations are large enough to drive the system from the high dipole moment state assumed during stable polarity epochs into the low dipole moment state. Since it is just a matter of chance which polarity is amplified during dipole recovery, reversals and grand excursions, i.e. excursions during which the dipole assumes reverse polarity, are equally likely. While the overall reversal behaviour seems Earth-like, a closer comparison to palaeomagnetic findings suggests that the simulated events last too long and that grand excursions are too rare. For a particularly large Ekman number we find a second but less Earth-like type of reversals where the total field decays and recovers after a certain time.

  16. Influence of hip and knee osteoarthritis on dynamic postural control parameters among older fallers.

    PubMed

    Mat, Sumaiyah; Ng, Chin Teck; Tan, Maw Pin

    2017-03-06

    To compare the relationship between postural control and knee and hip osteoarthritis in older adults with and without a history of falls. Fallers were those with ≥ 2 falls or 1 injurious fall over 12 months. Non-fallers were volunteers with no falls in the past year. Radiological evidence of osteoarthritis with no reported symptoms was considered "asymptomatic osteoarthritis", while "symptomatic osteoarthritis" was defined as radiographic osteoarthritis with pain or stiffness. Dynamic postural control was quantified with the limits of stability test measured on a balance platform (Neurocom® Balancemaster, California, USA). Parameters assessed were end-point excursion, maximal excursion, and directional control. A total of 102 older individuals, mean age 73 years (standard deviation 5.7) years were included. The association between falls and poor performance in maximal excursion and directional control was confounded by age and comorbidities. In the same linear equation model with falls, symptomatic osteoarthritis remained independently associated with poor end-point excursion (β-coefficient (95% confidence interval) -6.80 (-12.14 to -1.42)). Poor performance in dynamic postural control (maximal excursion and directional control) among fallers was not accounted for by hip/knee osteoarthritis, but was confounded by old age and comorbidities. Loss of postural control due to hip/knee osteoarthritis is not a risk factor for falls among community-dwelling older adults.

  17. Carbon isotopic shift and its cause at the Wuchiapingian-Changhsingian boundary in the Upper Permian at the Zhaojiaba section, South China: Evidences from multiple geochemical proxies

    NASA Astrophysics Data System (ADS)

    Wei, Hengye; Yu, Hao; Wang, Jianguo; Qiu, Zhen; Xiang, Lei; Shi, Guo

    2015-06-01

    The Late Permian environmental change, connecting the Guadalupian-Lopingian (G-L) (Middle-Upper Permian) boundary mass extinction and the Permain-Triassic (P-Tr) boundary mass extinction, has attracted more and more attentions. A significant negative shift for carbon isotope had been found at the Wuchiapingian-Changhsingian (W-C) boundary in the Upper Permian recently. However, the cause(s) of this negative excursion is still unknown. To resolve this problem, we analyzed the bulk organic carbon isotope, total organic carbon (TOC) content, pyritic sulfur (Spy) content, major element concentrations, and molecular organic biomarkers in the Wujiaping and Dalong formations in the Upper Permian from the Zhaojiaba section in western Hubei province, South China. Our results show that (1) there was a significant negative excursion in organic carbon isotopes at the W-C boundary and again a negative excursion at the top of Changhsingian stage; (2) the significant negative excursion at the W-C boundary was probably a global signal and mainly caused by the low primary productivity; and (3) the negative carbon isotope excursion at the top of Changhsingian was probably caused by the Siberian Traps eruptions. A decline in oceanic primary productivity at the W-C boundary probably represents a disturbance of the marine food web, leading to a vulnerable ecosystem prior to the P-Tr boundary mass extinction.

  18. Bilateral improvements in lower extremity function after unilateral balance training in individuals with chronic ankle instability.

    PubMed

    Hale, Sheri A; Fergus, Andrea; Axmacher, Rachel; Kiser, Kimberly

    2014-01-01

    Bilateral improvements in postural control have been reported among individuals with acute lateral ankle sprains and individuals with chronic ankle instability (CAI) when only the unstable ankle is rehabilitated. We do not know if training the stable ankle will improve function on the unstable side. To explore the effects of a unilateral balance-training program on bilateral lower extremity balance and function in individuals with CAI when only the stable limb is trained. Cohort study. University clinical research laboratory. A total of 34 volunteers (8 men, 26 women; age = 24.32 ± 4.95 years, height = 167.01 ± 9.45 cm, mass = 77.54 ± 23.76 kg) with CAI were assigned to the rehabilitation (n = 17) or control (n = 17) group. Of those, 27 (13 rehabilitation group, 14 control group) completed the study. Balance training twice weekly for 4 weeks. Foot and Ankle Disability Index (FADI), FADI Sport (FADI-S), Star Excursion Balance Test, and Balance Error Scoring System. The rehabilitation and control groups differed in changes in FADI-S and Star Excursion Balance Test scores over time. Only the rehabilitation group improved in the FADI-S and in the posteromedial and anterior reaches of the Star Excursion Balance Test. Both groups demonstrated improvements in posterolateral reach; however, the rehabilitation group demonstrated greater improvement than the control group. When the groups were combined, participants reported improvements in FADI and FADI-S scores for the unstable ankle but not the stable ankle. Our data suggest training the stable ankle may result in improvements in balance and lower extremity function in the unstable ankle. This further supports the existence of a centrally mediated mechanism in the development of postural-control deficits after injury, as well as improved postural control after rehabilitation.

  19. Non-invasive assessment determine the swallowing and respiration dysfunction in early Parkinson's disease.

    PubMed

    Wang, Chin-Man; Shieh, Wann-Yun; Weng, Yi-Hsin; Hsu, Yi-Hsuan; Wu, Yih-Ru

    2017-09-01

    Dysphagia is common among patients with Parkinson's disease. Swallowing and its coordination with respiration is extremely important to achieve safety swallowing. Different tools have been used to assess this coordination, however the results have been inconsistent. We aimed to investigate this coordination in patients with Parkinson's disease using a non-invasive method. Signals of submental muscle activity, thyroid cartilage excursion, and nasal airflow during swallowing were recorded simultaneously. Five different water boluses were swallowed three times, and the data were recorded and analyzed. Thirty-seven controls and 42 patients with early-stage Parkinson's disease were included. The rates of non-expiratory/expiratory pre- and post-swallowing respiratory phase patterns were higher in the patients than in the controls (P < 0.001). The rates of piecemeal deglutition when swallowing 10-ml and 20-ml water boluses and overall were also significantly higher in the patients (all P < 0.001). There were differences in oropharyngeal swallowing parameters between the patients and controls, including a pharyngeal phase delay with longer total excursion duration and excursion time in the patients swallowing small water boluses (1 ml, 3 ml and 5 ml), but no difference in the length of swallowing respiratory pause. Oropharyngeal swallowing and its coordination with respiration are affected in patients with early-stage Parkinson's disease, and safety compensation mechanisms were used more than efficiency during swallowing. The results of this study may serve as a baseline for further research into new treatment regimens and to improve the management of swallowing in patients with Parkinson's disease. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Changes in CO2 during Ocean Anoxic Event 1d indicate similarities to other carbon cycle perturbations

    NASA Astrophysics Data System (ADS)

    Richey, Jon D.; Upchurch, Garland R.; Montañez, Isabel P.; Lomax, Barry H.; Suarez, Marina B.; Crout, Neil M. J.; Joeckel, R. M.; Ludvigson, Greg A.; Smith, Jon J.

    2018-06-01

    Past greenhouse intervals of the Mesozoic were repeatedly punctuated by Ocean Anoxic Events (OAEs), major perturbations to the global carbon cycle and abrupt climate changes that may serve as relevant analogs for Earth's greenhouse gas-forced climate future. The key to better understanding these transient climate disruptions and possible CO2-forced tipping-points resides in high-resolution, precise, and accurate estimates of atmospheric CO2 for individual OAEs. Here we present a high-temporal resolution, multi-proxy pCO2 reconstruction for the onset of mid-Cretaceous (Albian-Cenomanian Boundary) OAE1d. Coupling of pCO2 estimates with carbon isotopic compositions (δ13C) of charcoal, vitrain, and cuticle from the Rose Creek Pit (RCP), Nebraska, reveals complex phasing, including a lag between the well-documented negative δ13C excursion defining the onset of OAE1d and the CO2 increase. This lag indicates that increased CO2 or other C-based greenhouse gases may not have been the primary cause of the negative excursion. Our study reveals a pCO2 increase within the interval of the negative δ13C excursion, reaching a maximum of up to ∼840 ppm (95% confidence interval -307 ppm/+167 ppm) toward its end. The reconstructed magnitude of CO2 increase (∼357 ppm) is similar to that of Late Cretaceous OAE2 but of smaller magnitude than that of other major carbon cycle perturbations of the Mesozoic assessed via stomatal methods (e.g., the Toarcian OAE [TOAE], Triassic-Jurassic boundary event, Cretaceous-Paleogene Boundary event). Furthermore, our results indicate a possible shared causal or developmental mechanism with OAE1a and the TOAE.

  1. 46 CFR 176.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., survival craft, life jacket, fire safety, and manning standards applicable to a vessel in the service for... may carry, the crew required, any additional lifesaving or safety equipment required, the route for... waive the applicable minimum safety standards when issuing an excursion permit. In particular, a vessel...

  2. 46 CFR 176.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., survival craft, life jacket, fire safety, and manning standards applicable to a vessel in the service for... may carry, the crew required, any additional lifesaving or safety equipment required, the route for... waive the applicable minimum safety standards when issuing an excursion permit. In particular, a vessel...

  3. 46 CFR 176.204 - Permit to carry excursion party.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., survival craft, life jacket, fire safety, and manning standards applicable to a vessel in the service for... may carry, the crew required, any additional lifesaving or safety equipment required, the route for... waive the applicable minimum safety standards when issuing an excursion permit. In particular, a vessel...

  4. 40 CFR 63.1334 - Parameter monitoring levels and excursions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... period for the storage vessel. (ii) If the monitoring plan does not specify monitoring a parameter and... semiannually or quarterly. The first semiannual period is the 6-month period starting the date the Notification... period—two excused excursions. (6) For the sixth and all subsequent semiannual periods—one excused...

  5. Physical and chemical evolution of reduced organic matter in the ISM

    NASA Technical Reports Server (NTRS)

    Jenniskens, Peter; Blake, David F.

    1995-01-01

    Icy mantles on interstellar grains have been a topic of study in airborne astronomy. Recent laboratory analog studies of the yield of organic residue from UV photolyzed ices have shown that this mechanism can be the most significant source of complex reduced organic matter in the interstellar medium. However, the total yield is a function of the occurrence of heating events that evaporate the ice, i.e. T is greater than 130 K, and the mechanism for such events is debated. Recently, we proposed that the recombination of radicals in the ice does not need high temperature excursions and, instead, occurs during a structural transformation of water ice at temperatures in the range 38 - 68 K.

  6. Magnetic resonance and diffusion tensor imaging analyses indicate heterogeneous strains along human medial gastrocnemius fascicles caused by submaximal plantar-flexion activity.

    PubMed

    Karakuzu, Agah; Pamuk, Uluç; Ozturk, Cengizhan; Acar, Burak; Yucesoy, Can A

    2017-05-24

    Sarcomere length changes are central to force production and excursion of skeletal muscle. Previous modeling indicates non-uniformity of that if mechanical interaction of muscle with its surrounding muscular and connective tissues is taken into account. Hence, quantifying length changes along the fascicles of activated human muscle in vivo is crucial, but this is lacking due to technical complexities. Combining magnetic resonance imaging deformation analyses and diffusion tensor imaging tractography, the aim was to test the hypothesis that submaximal plantar flexion activity at 15% MVC causes heterogeneous length changes along the fascicles of human medial gastrocnemius (GM) muscle. A general fascicle strain distribution pattern shown for all subjects indicates that proximal track segments are shortened, whereas distal ones are lengthened (e.g., by 13% and 29%, respectively). Mean fiber direction strains of different tracts also shows heterogeneity (for up to 57.5% of the fascicles). Inter-subject variability of amplitude and distribution of fascicle strains is notable. These findings confirm the hypothesis and are solid indicators for the functionally dependent mechanics of human muscle, in vivo. Heterogeneity of fascicle strains can be explained by epimuscular myofascial force transmission. To the best of our knowledge, this is the first study, which quantified local deformations along human skeletal muscle fascicles caused by sustained submaximal activation. The present approach and indicated fascicle strain heterogeneity has numerous implications for muscle function in health and disease to estimate the muscle's contribution to the joint moment and excursion and to evaluate mechanisms of muscle injury and several treatment techniques. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. The Hirnantian δ13C Positive Excursion in the Nabiullino Section (South Urals)

    NASA Astrophysics Data System (ADS)

    Yakupov, R. R.; Mavrinskaya, T. M.; Smoleva, I. V.

    2018-02-01

    The upper Sandbian, Katian, and Hirnantian complexes of conodonts in the upper Ordovician section of the western slope of the Southern Urals near the village of Nabiullino were studied. The δ13C positive excursion with a maximum of 3.3‰ associated with the global Hirnantian isotopic event, HICE, was fixed for the first time. This excursion shows the beginning of the Hirnantian stage in the terrigenous-carbonate section of the upper Ordovician in the Southern Urals. It coincides with the first occurrence of the Hirnantian conodont species of Gamachignathus ensifer and the conodonts of shallow-water biophacies, Aphelognathus-Ozarkodina, reflecting the global glacio-eustatic event.

  8. Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) Systems Integration Strategy

    NASA Technical Reports Server (NTRS)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

    2011-01-01

    The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a rapid prototyping approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process was based on a rapid prototyping approach. Tailored design review and test and integration processes facilitated that approach. The use of collaboration tools including electronic tools as well as documentation enabled a geographically distributed team take a paper concept to an operational prototype in approximately one year. One of the major tools used in the integration strategy was a coordinated effort to accurately model all the subsystems using computer aided design (CAD), so conflicts were identified before physical components came together. A deliberate effort was made following the deployment of the HDU PEM for field operations to collect lessons learned to facilitate process improvement and inform the design of future flight or analog versions of habitat systems. Significant items within those lessons learned were limitations with the CAD integration approach and the impact of shell design on flexibility of placing systems within the HDU shell.

  9. Multicultural Group Work on Field Excursions to Promote Student Teachers' Intercultural Competence

    ERIC Educational Resources Information Center

    Brendel, Nina; Aksit, Fisun; Aksit, Selahattin; Schrüfer, Gabriele

    2016-01-01

    As a response to the intercultural challenges of Geography Education, this study seeks to determine factors fostering intercultural competence of student teachers. Based on a one-week multicultural field excursion of eight German and eight Turkish students in Kayseri (Turkey) on Education for Sustainable Development, we used qualitative interviews…

  10. Enabling the Development of Student Teacher Professional Identity through Vicarious Learning during an Educational Excursion

    ERIC Educational Resources Information Center

    Steenekamp, Karen; van der Merwe, Martyn; Mehmedova, Aygul Salieva

    2018-01-01

    This paper explores the views of student teachers who were provided vicarious learning opportunities during an educational excursion, and how the learning enabled them to develop their teacher professional identity. This qualitative research study, using a social-constructivist lens highlights how vicarious learning influenced student teachers'…

  11. Dating the Laschamp Excursion: Why Speleothems are Valuable Tools for Constraining the Timing and Duration of Short-Lived Geomagnetic Events

    NASA Astrophysics Data System (ADS)

    Lascu, I.; Feinberg, J. M.; Dorale, J. A.; Cheng, H.; Edwards, R. L.

    2015-12-01

    Short-lived geomagnetic events are reflections of geodynamo behavior at small length scales. A rigorous documentation of the anatomy, timing, duration, and frequency of centennial-to-millennial scale geomagnetic events can be invaluable for theoretical and numerical geodynamo models, and for the understanding the finer dynamics of the Earth's core. A critical ingredient for characterizing such geomagnetic instabilities are tightly constrained age models that enable high-resolution magnetostratigraphies. Here we focus on a North American speleothem geomagnetic record of the Laschamp excursion, which was the first geomagnetic excursion recognized and described in the paleomagnetic record, and remains the most studied event of its kind. The geological significance of the Laschamp lies chiefly in the fact that it constitutes a global time-synchronous geochronological marker. The Laschamp excursion occurred around the time of the demise of Homo neanderthalensis, in conjunction with high-amplitude, rapid climatic oscillations leading into the Last Glacial Maximum, and precedes a major supervolcano eruption in the Mediterranean. Thus, the precise determination of the timing and duration of the Laschamp would help in elucidating major scientific questions situated at the intersection of geology, paleoclimatology, and anthropology. Here we present a geomagnetic record from a stalagmite collected in Crevice Cave, Missouri, which we have dated using a combination of high-precision 230Th ages and annual layer counting using confocal microscopy. We have found a maximum duration for the Laschamp that spans the interval 42,250-39,700 years BP, and an age of 41,100 ± 350 years BP for the height of the excursion. During this period relative paleointensity decreased by an order of magnitude and the virtual geomagnetic pole was located at southerly latitudes. Our chronology provides the first robust bracketing for the Laschamp excursion, and improves on previous age determinations based on 40Ar/39Ar dating of lava flows, and orbitally-tuned sedimentary and ice-core records.

  12. Glycemic excursions are positively associated with changes in duration of asymptomatic hypoglycemia after treatment intensification in patients with type 2 diabetes.

    PubMed

    Wang, Jun-Sing; Lee, I-Te; Lee, Wen-Jane; Lin, Shi-Dou; Su, Shih-Li; Tu, Shih-Te; Tseng, Yao-Hsien; Lin, Shih-Yi; Sheu, Wayne Huey-Herng

    2016-03-01

    The aim of this study was to examine the association between glycemic excursions and duration of hypoglycemia after treatment intensification in patients with type 2 diabetes (T2D). Patients with T2D on oral anti-diabetes drug (OAD) with glycated hemoglobin (HbA1c) of 7.0-11.0% were switched to metformin monotherapy (500 mg thrice daily) for 8 weeks, followed by randomization to either glibenclamide or acarbose as add-on treatment for 16 weeks. Glycemic excursions were assessed as mean amplitude of glycemic excursions (MAGE) with 72-h ambulatory continuous glucose monitoring (CGM) before randomization and at the end of study. Hypoglycemia was defined as sensor glucose level of less than 60 mg/dl in two or more consecutive readings from CGM. A total of 50 patients (mean age 53.5 ± 8.2 years, male 48%, mean baseline HbA1c 8.4 ± 1.2%) were analyzed. Duration of hypoglycemia significantly increased after treatment with glibenclamide (from 5.5 ± 13.8 to 18.8 ± 35.8 min/day, p=0.041), but not with acarbose (from 2.9 ± 10.9 to 14.7 ± 41.9 min/day, p=0.114). Post treatment MAGE was positively associated with change from baseline in duration of hypoglycemia after treatment with either glibenclamide (β coefficient 0.345, p=0.036) or acarbose (β coefficient 0.674, p=0.046). The association remained significant after multivariate adjustment (p<0.05 for all models). Post treatment glycemic excursions are associated with changes in duration of hypoglycemia after treatment intensification with OAD in patients with T2D. Glycemic excursions should be an important treatment target for T2D to reduce the risk of hypoglycemia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. Is the Earth's magnetic field heading for a flip? Hints from the past

    NASA Astrophysics Data System (ADS)

    Laj, C. E.; Kissel, C.

    2017-12-01

    The magnitude of the Earth's dipole magnetic field has decreased significantly over the last centuries at a mean rate of 16 nT/y. This decrease, which correlates with the growth of the South Atlantic Anomaly (SAA) therefore occurs at a rate which is about 10 times larger than expected from a free Ohmic decay process. This situation has led to speculations that an attempt to a reversal or a geomagnetic excursion might be underway. We investigate this hypothesis by examining past geomagnetic instabilities, focussing on the well documented Laschamp and Mono Lake excursions. We have selected high accumulation sedimentary records with very precise age model, leading to unprecedented temporal resolution, and accurate calibration of RPI between 20 and 75 kyr B.P. We also used the 10Be and 36Cl records from the Greenland ice cores. The rate of decay of the field intensity during these two excursions is virtually identical to that observed over the last centuries and much higher than that observed for another period of low intensity (around 65 kyr BP) not associated with a polarity change. Moreover, the global morphology of the Laschamp excursion obtained by Bayesian inversion (Leonhardt et al. (2009) is that reverse magnetic field patches at the core-mantle boundary are formed near the equator and then move poleward, a scenario reminiscent of that described for the present field in the litterature. Therefore, although these results from two excursions do not provide undisputable information on future evolution of the field, they show similarities with several aspects of the present-day geomagnetic field. Assuming that the dynamo processes for an eventual future instability would be similar to those of the past two excursions, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, some 1000 years would be needed for the directional changes to start to be significant.

  14. Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study.

    PubMed

    Riboldi, Bárbara P; Luft, Vivian C; de Castilhos, Cristina D; de Cardoso, Letícia O; Schmidt, Maria I; Barreto, Sandhi M; de Sander, Maria F; Alvim, Sheila M; Duncan, Bruce B

    2015-02-13

    To assess glucose and triglyceride excursions 2 hours after the ingestion of a standardized meal and their associations with clinical characteristics and cardiovascular complications in individuals with diabetes. Blood samples of 898 subjects with diabetes were collected at fasting and 2 hours after a meal containing 455 kcal, 14 g of saturated fat and 47 g of carbohydrates. Self-reported morbidity, socio-demographic characteristics and clinical measures were obtained by interview and exams performed at the baseline visit of the ELSA-Brasil cohort study. Median (interquartile range, IQR) for fasting glucose was 150.5 (123-198) mg/dL and for fasting triglycerides 140 (103-199) mg/dL. The median excursion for glucose was 45 (15-76) mg/dL and for triglycerides 26 (11-45) mg/dL. In multiple linear regression, a greater glucose excursion was associated with higher glycated hemoglobin (10.7, 95% CI 9.1-12.3 mg/dL), duration of diabetes (4.5; 2.6-6.4 mg/dL, per 5 year increase), insulin use (44.4; 31.7-57.1 mg/dL), and age (6.1; 2.5-9.6 mg/dL, per 10 year increase); and with lower body mass index (-5.6; -8.4- -2.8 mg/dL, per 5 kg/m2 increase). In adjusted logistic regression models, a greater glucose excursion was marginally associated with the presence of cardiovascular comorbidities (coronary heart disease, myocardial infarction and angina) in those with obesity. A greater postprandial glycemic response to a small meal was positively associated with indicators of a decreased capacity for insulin secretion and negatively associated with obesity. No pattern of response was observed with a greater postprandial triglyceride excursion.

  15. Alarms based on real-time sensor glucose values alert patients to hypo- and hyperglycemia: the guardian continuous monitoring system.

    PubMed

    Bode, Bruce; Gross, Kenneth; Rikalo, Nancy; Schwartz, Sherwyn; Wahl, Timothy; Page, Casey; Gross, Todd; Mastrototaro, John

    2004-04-01

    The purposes of this study were to demonstrate the accuracy and effectiveness of the Guardian Continuous Monitoring System (Medtronic MiniMed, Northridge, California) and to demonstrate that the application of real-time alarms to continuous monitoring alerts users to hypo and hyperglycemia and reduces excursions in people with diabetes. A total of 71 subjects with type 1 diabetes, mean hemoglobin A1c of 7.6 +/- 1.1%, age 44.0 +/- 11.4 years, and duration of diabetes 23.6 +/- 10.6 years were enrolled in this two-period, randomized, multicenter study. Subjects were randomized into either an Alert group or a Control group. The accuracy of the Guardian was evaluated by treating the study data as a single-sample correlational design. Effectiveness of the Guardian alerts was evaluated by comparing the Alert group with the Control group. The mean (median) absolute relative error between home blood glucose meter readings and sensor values was 21.3% (17.3%), and the Guardian, on average, read 12.8 mg/dL below the concurrent home blood glucose meter readings. The hypoglycemia alert was able to distinguished glucose values < or =70 mg/dL with 67% sensitivity, 90% specificity, and 47% false alerts. The hyperglycemia alert showed a similar ability to detect sensor values > or =250 mg/dL with 63% sensitivity, 97% specificity, and 19% false alerts. The Alert group demonstrated a median decrease in the duration of hypoglycemic excursions (-27.8 min) that was significantly greater than the median decrease in the duration of hypoglycemic excursions in the Control group (-4.5 min) (P = 0.03). A marginally significant increase in the frequency of hyperglycemic excursions (P = 0.07) between Period 1 and Period 2 was accompanied by a decrease of 9.6 min in the duration of hyperglycemic excursions in the Alert group. Glucose measurements differ between blood samples taken from the finger and interstitial fluid, especially when levels are changing rapidly; however, these results demonstrate that the Guardian is reasonably accurate while performing continuous glucose monitoring. The subjects' responses to hypoglycemia alerts resulted in a significant reduction in the duration of hypoglycemic excursions; however, overtreating hypoglycemia may have resulted in a marginally significant increase in the frequency of hyperglycemic excursions.

  16. The effect of Kinesio Taping on postural control in subjects with non-specific chronic low back pain.

    PubMed

    Abbasi, Soheila; Rojhani-Shirazi, Zahra; Shokri, Esmaeil; García-Muro San José, Francisco

    2018-04-01

    The aim of this study was to investigate the possible alterations in postural control during upright standing in subjects with non-specific chronic low back pain and the effect of Kinesio taping on the postural control. Twenty subjects with non-specific chronic low back pain and twenty healthy subjects participated in this study. The center of pressure excursion was evaluated before the intervention for both groups, and immediately after intervention for the low back pain group. Independent sample t-test, Mann-Whitney test and repeated measure ANOVA were used for the statistical analysis of the data. There were significant differences in the center of pressure excursion between the low back pain group versus the healthy group. The results of the ANOVA demonstrated a statistically significant difference in the mean COP displacement and velocity before Kinesio Taping, immediately after, and 24 h after in the low back pain group. There are poor postural control mechanisms in subjects with non-specific chronic low back pain. Kinesio taping seems to change postural control immediately and have lasting effects until the day after. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Students' Long-Term Memories from an Ecology Field Excursion: Retelling a Narrative as an Interplay between Implicit and Explicit Memories

    ERIC Educational Resources Information Center

    Stolpe, Karin; Bjorklund, Lars

    2013-01-01

    This study aims to investigate the science content remembered by biology students 6 and 12 months after an ecology excursion. The students' memories were tested during a stimulated recall interview. The authors identified three different types of memories: "recall," "recognition" and "narratives." The "dual…

  18. A Review of Criticality Accidents 2000 Revision

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas P. McLaughlin; Shean P. Monahan; Norman L. Pruvost

    Criticality accidents and the characteristics of prompt power excursions are discussed. Sixty accidental power excursions are reviewed. Sufficient detail is provided to enable the reader to understand the physical situation, the chemistry and material flow, and when available the administrative setting leading up to the time of the accident. Information on the power history, energy release, consequences, and causes are also included when available. For those accidents that occurred in process plants, two new sections have been included in this revision. The first is an analysis and summary of the physical and neutronic features of the chain reacting systems. Themore » second is a compilation of observations and lessons learned. Excursions associated with large power reactors are not included in this report.« less

  19. Predictors of chronic ankle instability: Analysis of peroneal reaction time, dynamic balance and isokinetic strength.

    PubMed

    Sierra-Guzmán, Rafael; Jiménez, Fernando; Abián-Vicén, Javier

    2018-05-01

    Previous studies have reported the factors contributing to chronic ankle instability, which could lead to more effective treatments. However, factors such as the reflex response and ankle muscle strength have not been taken into account in previous investigations. Fifty recreational athletes with chronic ankle instability and 55 healthy controls were recruited. Peroneal reaction time in response to sudden inversion, isokinetic evertor muscle strength and dynamic balance with the Star Excursion Balance Test and the Biodex Stability System were measured. The relationship between the Cumberland Ankle Instability Tool score and performance on each test was assessed and a backward multiple linear regression analysis was conducted. Participants with chronic ankle instability showed prolonged peroneal reaction time, poor performance in the Biodex Stability System and decreased reach distance in the Star Excursion Balance Test. No significant differences were found in eversion and inversion peak torque. Moderate correlations were found between the Cumberland Ankle Instability Tool score and the peroneal reaction time and performance on the Star Excursion Balance Test. Peroneus brevis reaction time and the posteromedial and lateral directions of the Star Excursion Balance Test accounted for 36% of the variance in the Cumberland Ankle Instability Tool. Dynamic balance deficits and delayed peroneal reaction time are present in participants with chronic ankle instability. Peroneus brevis reaction time and the posteromedial and lateral directions of the Star Excursion Balance Test were the main contributing factors to the Cumberland Ankle Instability Tool score. No clear strength impairments were reported in unstable ankles. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Kinematic predictors of star excursion balance test performance in individuals with chronic ankle instability.

    PubMed

    Hoch, Matthew C; Gaven, Stacey L; Weinhandl, Joshua T

    2016-06-01

    The Star Excursion Balance Test has identified dynamic postural control deficits in individuals with chronic ankle instability. While kinematic predictors of Star Excursion Balance Test performance have been evaluated in healthy individuals, this has not been thoroughly examined in individuals with chronic ankle instability. Fifteen individuals with chronic ankle instability completed the anterior reach direction of the Star Excursion Balance Test and weight-bearing dorsiflexion assessments. Maximum reach distances on the Star Excursion Balance Test were measured in cm and normalized to leg length. Three-dimensional trunk, hip, knee, and ankle motion of the stance limb were recorded during each anterior reach trial using a motion capture system. Sagittal, frontal, and transverse plane displacement observed from trial initiation to the point of maximum reach was calculated for each joint or segment and averaged for analysis. Pearson product-moment correlations were performed to examine the relationships between kinematic variables, maximal reach, and weight-bearing dorsiflexion. A backward multiple linear regression model was developed with maximal reach as the criterion variable and kinematic variables as predictors. Frontal plane displacement of the trunk, hip, and ankle and sagittal plane knee displacement were entered into the analysis. The final model (p=0.004) included all three frontal plane variables and explained 81% of the variance in maximal reach. Maximal reach distance and several kinematic variables were significantly related to weight-bearing dorsiflexion. Individuals with chronic ankle instability who demonstrated greater lateral trunk displacement toward the stance limb, hip adduction, and ankle eversion achieved greater maximal reach. Copyright © 2016. Published by Elsevier Ltd.

  1. Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-hour glucose and insulin excursions

    USDA-ARS?s Scientific Manuscript database

    It has been proposed that the adverse metabolic effects of chronic consumption of sugar-sweetened beverages which contain both glucose and fructose are a consequence of increased circulating glucose and insulin excursions, i.e dietary glycemic index (GI). Objective: We determined if the greater adv...

  2. A Teaching-Learning Sequence of Colour Informed by History and Philosophy of Science

    ERIC Educational Resources Information Center

    Maurício, Paulo; Valente, Bianor; Chagas, Isabel

    2017-01-01

    In this work, we present a teaching-learning sequence on colour intended to a pre-service elementary teacher programme informed by History and Philosophy of Science. Working in a socio-constructivist framework, we made an excursion on the history of colour. Our excursion through history of colour, as well as the reported misconception on colour…

  3. A Normative-Speaker Validation Study of Two Indices Developed to Quantify Tongue Dorsum Activity from Midsagittal Tongue Shapes

    ERIC Educational Resources Information Center

    Zharkova, Natalia

    2013-01-01

    This study reported adult scores on two measures of tongue shape, based on midsagittal tongue shape data from ultrasound imaging. One of the measures quantified the extent of tongue dorsum excursion, and the other measure represented the place of maximal excursion. Data from six adult speakers of Scottish Standard English without speech disorders…

  4. Tuning the Field Trip: Audio-Guided Tours as a Replacement for 1-Day Excursions in Human Geography

    ERIC Educational Resources Information Center

    Wissmann, Torsten

    2013-01-01

    Educators are experiencing difficulties with 1-day field trips in human geography. Instead of teaching students how to apply theory in the field and learn to "sense" geography in everyday life, many excursions have degraded into tourist-like events where lecturers try to motivate rather passive students against a noisy urban backdrop.…

  5. Conference Committees: Conference Committees

    NASA Astrophysics Data System (ADS)

    2009-09-01

    International Programm Committee (IPC) Harald Ade NCSU Sadao Aoki University Tsukuba David Attwood Lawrence Berkeley National Laboratory/CXRO Christian David Paul Scherrer Institut Peter Fischer Lawrence Berkeley National Laboratory Adam Hitchcock McMaster University Chris Jacobsen SUNY, Stony Brook Denis Joyeux Lab Charles Fabry de l'Institut d'Optique Yasushi Kagoshima University of Hyogo Hiroshi Kihara Kansai Medical University Janos Kirz SUNY Stony Brook Maya Kiskinova ELETTRA Ian McNulty Argonne National Lab/APS Alan Michette Kings College London Graeme Morrison Kings College London Keith Nugent University of Melbourne Zhu Peiping BSRF Institute of High Energy Physics Francois Polack Soleil Christoph Quitmann Paul Scherrer Institut Günther Schmahl University Göttingen Gerd Schneider Bessy Hyun-Joon Shin Pohang Accelerator Lab Jean Susini ESRF Mau-Tsu Tang NSRRC Tony Warwick Lawrence Berkeley Lab/ALS Local Organizing Committee Christoph Quitmann Chair, Scientific Program Charlotte Heer Secretary Christian David Scientific Program Frithjof Nolting Scientific Program Franz Pfeiffer Scientific Program Marco Stampanoni Scientific Program Robert Rudolph Sponsoring, Financials Alfred Waser Industry Exhibition Robert Keller Public Relation Markus Knecht Computing and WWW Annick Cavedon Proceedings and Excursions and Accompanying Persons Program Margrit Eichler Excursions and Accompanying Persons Program Kathy Eikenberry Excursions and Accompanying Persons Program Marlies Locher Excursions and Accompanying Persons Program

  6. Age of the Mono Lake excursion and associated tephra

    USGS Publications Warehouse

    Benson, L.; Liddicoat, J.; Smoot, J.; Sarna-Wojcicki, A.; Negrini, R.; Lund, S.

    2003-01-01

    The Mono Lake excursion (MLE) is an important time marker that has been found in lake and marine sediments across much of the Northern Hemisphere. Dating of this event at its type locality, the Mono Basin of California, has yielded controversial results with the most recent effort concluding that the MLE may actually be the Laschamp excursion (Earth Planet. Sci. Lett. 197 (2002) 151). We show that a volcanic tephra (Ash #15) that occurs near the midpoint of the MLE has a date (not corrected for reservoir effect) of 28,620 ?? 300 14C yr BP (??? 32,400 GISP2 yr BP) in the Pyramid Lake Basin of Nevada. Given the location of Ash #15 and the duration of the MLE in the Mono Basin, the event occurred between 31,500 and 33,300 GISP2 yr BP, an age range consistent with the position and age of the uppermost of two paleointensity minima in the NAPIS-75 stack that has been associated with the MLE (Philos. Trans. R. Soc. London Ser. A 358 (2000) 1009). The lower paleointensity minimum in the NAPIS-75 stack is considered to be the Laschamp excursion (Philos. Trans. R. Soc. London Ser. A 358 (2000) 1009).

  7. The Flores speleothem carbon isotope record: vegetation, volcanism and the demise of Homo floresiensis

    NASA Astrophysics Data System (ADS)

    Scroxton, N.; Gagan, M. K.; Ayliffe, L. K.; Hantoro, W. S.; Hellstrom, J. C.; Cheng, H.; Edwards, R. L.; Zhao, J. X.; Suwargadi, B. W.; Scott-Gagan, H.; Cowley, J. A.; Rifai, H.

    2015-12-01

    The last surviving non-human member of the Homo genus: Homo floresiensis, disappeared from the stratigraphic record in Liang Bua cave, Flores, Indonesia, between 17 and 10 kyr BP (Roberts et al. 2009, J. Hum. Evol.). The cause of the disappearance (e.g. climate change, volcanic catastrophe or human competition) has not been established. Here, we present a new 92,000-year long speleothem δ13C record for Liang Luar cave, 800m South of Liang Bua. Our record acts as a proxy for local environmental and vegetation health throughout H. floresiensis' occupation of the area. The Liang Luar speleothem δ13C record is primarily a record of vegetation productivity and soil respiration rates, highlighting local ecological responses to changing regional and global climate forcings such as temperature, atmospheric pCO2 and precipitation amount. Changes in speleothem δ13C can largely be considered an environmental response to climate change. Events that caused significant harm to the local environment and H. floresiensis are likely to be outside the natural range of variability: being quick enough or extreme enough that adaptation to new conditions is not possible. We identify disturbances to the vegetation system using two indicators in the speleothem record. 1) Abrupt positive δ13C excursions which indicate periods of reduced vegetative activity. 2) A loss of correlation between the δ13C and δ18O records, indicating that precipitation is no longer a dominant control on vegetation productivity. The largest (8‰) and longest (7 kyr) abrupt positive excursion, the 68 kyr event, sees positive speleothem δ13C values, due to increased bedrock contribution and/or C4 vegetation at this time. Crucially a H. floresiensis occupation interval dates to this period. The largest abrupt deterioration in vegetation (positive δ13C excursion) between 17 and 10 kyr BP is a 1 in 5kyr occurrence - An event of a magnitude that was likely encountered and survived by H. floresiensis multiple times during the last 90kyr. The mechanism/s that led to the disappearance of H. floresiensis must have been highly selective, and did not have a major impact on the local environment. This seemingly rules out volcanism and climate change as potential agents, leaving us with an intriguing puzzle as to what caused the recent extinction of Homo floresiensis.

  8. Microbially mediated carbon cycling as a control on the δ 13C of sedimentary carbon in eutrophic Lake Mendota (USA): new models for interpreting isotopic excursions in the sedimentary record

    NASA Astrophysics Data System (ADS)

    Hollander, David J.; Smith, Michael A.

    2001-12-01

    An isotopic study of various carbon phases in eutrophic Lake Mendota (Wisconsin, USA) indicates that the δ13C composition of sedimentary organic and inorganic carbon has become more negative in response to increasing microbially mediated carbon cycling and processes associated with the intensification of seasonal and long-term eutrophication. Progressive increases in the contributions of isotopically depleted chemoautotrophic and methanotrophic biomass (reflected in the -40 to -90‰ values of hopanols and FAMES), attributed to seasonal and long-term increases in production and expansion of the anaerobic water mass, accounts for carbon isotopic trends towards depleted δ13C values observed in both seasonal varves and over the past 100 years. Changes in the intensities of certain microbial processes are also evident in the sedimentary geochemical record. During the period of most intense cultural eutrophication, when the oxic-anoxic interface was located close to the surface, methanogenesis/methanotrophy and the oxidation of biogenic methane increased to the extent that significant quantities of 13C-depleted CO2 were added into the epilimnion. This depleted CO2 was subsequently utilized by phytoplankton and incorporated into CaCO3 during biogenically induced calcite precipitation. A comparative study between eutrophic Lakes Mendota and Greifen, further indicate that the extent of nutrient loading in the epilimnion determines whether the δ13C record of sedimentary organic carbon reflects intensification of microbial processes in the hypolimnion and sediments, or changes in the primary productivity in the photic zone. From this comparison, a series of eutrophication models are developed to describe progressive transitions through thresholds of microbial and eukaryotic productivity and their influence on the δ13C record of sedimentary carbon. With increasing eutrophication, the models initially predict a negative and then a subsequent positive carbon isotopic excursion reflecting the changing influence of 13C-deleted microbial biomass relative to 13C-enriched photoautrophic biomass. These eutrophication models provide a framework to evaluate carbon cycling processes in modern environments and have significant implications for interpreting carbon isotopic excursions in the sedimentary record.

  9. A Quaternary Geomagnetic Instability Time Scale

    NASA Astrophysics Data System (ADS)

    Singer, B. S.

    2013-12-01

    Reversals and excursions of Earth's geomagnetic field create marker horizons that are readily detected in sedimentary and volcanic rocks worldwide. An accurate and precise chronology of these geomagnetic field instabilities is fundamental to understanding several aspects of Quaternary climate, dynamo processes, and surface processes. For example, stratigraphic correlation between marine sediment and polar ice records of climate change across the cryospheres benefits from a highly resolved record of reversals and excursions. The temporal patterns of dynamo behavior may reflect physical interactions between the molten outer core and the solid inner core or lowermost mantle. These interactions may control reversal frequency and shape the weak magnetic fields that arise during successive dynamo instabilities. Moreover, weakening of the axial dipole during reversals and excursions enhances the production of cosmogenic isotopes that are used in sediment and ice core stratigraphy and surface exposure dating. The Geomagnetic Instability Time Scale (GITS) is based on the direct dating of transitional polarity states recorded by lava flows using the 40Ar/39Ar method, in parallel with astrochronologic age models of marine sediments in which O isotope and magnetic records have been obtained. A review of data from Quaternary lava flows and sediments yields a GITS comprising 10 polarity reversals and 27 excursions during the past 2.6 million years. Nine of the ten reversals bounding chrons and subchrons are associated with 40Ar/39Ar ages of transitionally-magnetized lava flows. The tenth, the Guass-Matuyama chron boundary, is tightly bracketed by 40Ar/39Ar dated ash deposits. Of the 27 well-documented excursions, 14 occurred during the Matuyama chron and 13 during the Brunhes chron; 19 have been dated directly using the 40Ar/39Ar method on transitionally-magnetized volcanic rocks and form the backbone of the GITS. Excursions are clearly not the rare phenomena once thought. Rather, during the Quaternary period, they occur nearly three times as often as full polarity reversals. I will address analytical issues, including the size and consistency of system blanks, that have led to the recognition of minor (1%) discrepencies between the 40Ar/39Ar age for a particular reversal or excursion and the best astrochronologic estimates from ODP sediment cores. For example, re-analysis of lava flows from Haleakala volcano, Maui that record in detail the Matuyama-Brunhes polarity reversal have been undertaken with blanks an order of magntitude smaller and more stable than was common a decade ago. Using the modern astrochronologic calibration of 28.201 Ma for the age of the Fish Canyon sanidine standard, results thus far yield an 40Ar/39Ar age of 772 × 11 ka for the reversal that is identical to the most precise and accurate astrochronologic age of 773 × 2 ka for this reversal from ODP cores. Similarly, new dating of sanidine in the Cerro Santa Rosa I rhyolite dome, New Mexico reveals an age of 932 × 5 ka for the excursion it records, in perfect agreement with astrochronologically dated ODP core records. Work underway aims at refining the 40Ar/39Ar ages that underpin the entire GITS by further eliminating the bias between the radioisotopic and astrochronologically determined ages for several reversals and excursions.

  10. Geochemical Astro- and Geochronological Constraints on the Early Jurassic

    NASA Astrophysics Data System (ADS)

    Storm, M.; Condon, D. J.; Ruhl, M.; Jenkyns, H. C.; Hesselbo, S. P.; Al-Suwaidi, A. H.; Percival, L.

    2017-12-01

    The Early Jurassic Hettangian and Sinemurian time scales are poorly defined due to the lack of continuous geochemical records, and the temporal constrain of the Toarcian Oceanic Anoxic Event and associated global carbon cycle perturbation is afflicted by geochemical and biostratigraphical uncertainties of the existing radiometric dates from various volcanic ash bearing sections. Here we present a continuous, orbitally paced Hettangian to Pliensbachian carbon-isotope record of the Mochras drill-core (Cardigan bay Basin, UK). The record generates new insights into the evolution and driving mechanisms of the Early Jurassic carbon cycle, and is contributing to improve the Hettangian and Sinemurian time scale. Furthermore, we introduce a new high-resolution carbon-isotope chemostratigraphy, integrated with ammonite biostratigraphy and new U/Pb single zircon geochronology of the Las Overas section (Neuquén Basin, Argentina). The studied section comprises sediments from the tenuicostatum to Dumortiera Andean Ammonite zone (tenuicostatum to levesqui European standard zones). A stratigraphically expanded negative shift in d13Corg values, from -24‰ down to -32­‰, appears in the tenuicostatum and hoelderi ammonite zone, coeval to the negative excursion in European realm which is associated with the Toarcian Oceanic Anoxic Event. The negative isotope excursion appears concomitant with an increase in sedimentary mercury levels, indicating enhanced volcanic activity. TOC values and elemental data suggest a high sedimentation dilution in the tenuicostatum to pacificum zone. The new geochronological data from several volcanic ash beds throughout the section are further improving the temporal correlation between the Early Toarcian isotope event and causal mechanisms

  11. Right Ventricular Systolic Dysfunction in Chagas Disease Defined by Speckle-Tracking Echocardiography: A Comparative Study with Cardiac Magnetic Resonance Imaging.

    PubMed

    Moreira, Henrique T; Volpe, Gustavo J; Marin-Neto, José A; Nwabuo, Chike C; Ambale-Venkatesh, Bharath; Gali, Luis G; Almeida-Filho, Oswaldo C; Romano, Minna M D; Pazin-Filho, Antonio; Maciel, Benedito C; Lima, João A C; Schmidt, André

    2017-05-01

    Chagas disease leads to biventricular heart failure, usually with prominent systemic congestion. Although echocardiography is widely used in clinical routine, the utility of echocardiographic parameters to detect right ventricular (RV) systolic dysfunction in patients with Chagas disease is unknown. We sought to study the diagnostic value of echocardiography, including speckle-tracking parameters, to distinguish individuals with RV systolic dysfunction from those with normal RV systolic function in Chagas disease using cardiac magnetic resonance (CMR) as the reference method. In this cross-sectional study, 63 individuals with Chagas disease underwent echocardiography and CMR evaluations. Conventional echocardiographic parameters for RV functional evaluation were tricuspid annular plane systolic excursion, RV systolic excursion velocity, fractional area change, and RV index of myocardial performance. Strain and strain rate were obtained by two-dimensional speckle-tracking echocardiography and defined as "RV free wall," when based only in segments from RV free wall, or "RV free wall and septum," when segments from both free RV wall and interventricular septum were included. RV systolic dysfunction was defined as RV ejection fraction (RVEF) < 50% by CMR. Mean age was 56 ± 14 years, and 58.7% of the patients were men. RV systolic dysfunction was detected by CMR in 18 (28.6%) individuals. RV free wall strain showed the highest correlation with RVEF by CMR (r = -0.62, P < .001), followed by fractional area change (r = 0.56, P < .001), RV free wall and septum strain (r = -0.54, P < .001), RV free wall and septum strain rate (r = -0.47, P < .001), RV free wall strain rate (r = -0.45, P < .001), and RV systolic excursion velocity (r = 0.30, P = .016). The RV index of myocardial performance and tricuspid annular plane systolic excursion showed a small and not significant correlation with RVEF (r = -0.20, P = .320; r = 0.14; P = .289, respectively). Using predefined cutoffs for RV systolic dysfunction, RV free wall strain (>-22.5% for men and >-23.3% for women) exhibited the highest area under the receiver operating characteristic curve (area under the curve = 0.829) to differentiate the presence from the absence of RV systolic dysfunction in Chagas disease, with a sensitivity and specificity of 67% and 83%, respectively. RV free wall strain is an appropriate and superior echocardiographic variable for evaluating RV systolic function in Chagas disease, and it should be the method of choice for this purpose. Copyright © 2017 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

  12. Evaluation of pediatric ATD biofidelity as compared to child volunteers in low-speed far-side oblique and lateral impacts.

    PubMed

    Seacrist, Thomas; Locey, Caitlin M; Mathews, Emily A; Jones, Dakota L; Balasubramanian, Sriram; Maltese, Matthew R; Arbogast, Kristy B

    2014-01-01

    Motor vehicle crashes are a leading cause of injury and mortality for children. Mitigation of these injuries requires biofidelic anthropomorphic test devices (ATDs) to design and evaluate automotive safety systems. Effective countermeasures exist for frontal and near-side impacts but are limited for far-side impacts. Consequently, far-side impacts represent increased injury and mortality rates compared to frontal impacts. Thus, the objective of this study was to evaluate the biofidelity of the Hybrid III and Q-series pediatric ATDs in low-speed far-side impacts, with and without shoulder belt pretightening. Low-speed (2 g) far-side oblique (60°) and lateral (90°) sled tests were conducted using the Hybrid III and Q-series 6- and 10-year-old ATDs. ATDs were restrained by a lap and shoulder belt equipped with a precrash belt pretightener. Photoreflective targets were attached to the head, spine, shoulders, and sternum. ATDs were exposed to 8 low-speed sled tests: 2 oblique nontightened, 2 oblique pretightened, 2 lateral nontightened, 2 lateral pretightened. ATDs were compared with previously collected 9- to 11-year-old (n=10) volunteer data and newly collected 6- to 8-year-old volunteer data (n=7) tested with similar methods. Kinematic data were collected from a 3D target tracking system. Metrics of comparison included excursion, seat belt and seat pan reaction loads, belt-to-torso angle, and shoulder belt slip-out. The ATDs exhibited increased lateral excursion of the head top, C4, and T1 as well as increased downward excursion of the head top compared to the volunteers. Volunteers exhibited greater forward excursion than the ATDs in oblique nontightened impacts. These kinematics correspond to increased shoulder belt slip-out for the ATDs in oblique tests (ATDs=90%; volunteers=36%). Contrarily, similar shoulder belt slip-out was observed between ATDs and volunteers in lateral impacts (ATDs=80%; volunteers=78%). In pretightened impacts, the ATDs exhibited reduced lateral excursion and torso roll-out angle compared to the volunteers. In general, the ATDs overestimated lateral excursion in both impact directions, while underestimating forward excursion of the head and neck in oblique impacts compared to the pediatric volunteers. This was primarily due to pendulum-like lateral bending of the entire ATD torso compared to translation of the thorax relative to the abdomen prior to the lateral bending of the upper torso in the volunteers, likely due to the multisegmented spinal column in the volunteers. Additionally, the effect of belt pretightening on occupant kinematics was greater for the ATDs than the volunteers.

  13. New successful ideas to teach Earth Science to students older than 55 by means of trekking

    NASA Astrophysics Data System (ADS)

    Fernández Raga, María; Cerdà, Artemi; Civera, Cristina

    2013-04-01

    During the last 10 years, the Geograns Program within the NAUGRAN initiative of the University of Valencia is using trekking as a way to teach in the field Earth Science. This paper review the contribution of this program and show the results and future challenges. The life expectancy is growing all over the world. This is a clear trend in the Western societies where after two generations there is a large group of inhabitants that have a new life after retirement. The universities must understand that this new group of citizens need services that will allow them to know better the society. This is why the University of Valencia developed in the end of the 90's a program to teach to students older than 55. The program that allows to those students to attend lectures at the University is called NAUGRAN. This is a program for more than one thousand students that cover the needs of a group that is having more and more population over the age of 55, and with a life expectancy that surpass the 81 years in Spain. Teaching History, Arts, Sciences or Literature can be easily due for those 55-old students. However, teaching geosciences is being very difficult, as the students must visit the field and the laboratory. Within the GEOGRANS project, and during the last six years, Physical Geography was taught to students older than 55 in independent lecture rooms and field and laboratory classes. The main strategy was to show them the concepts and the ideas of the Physical Geography in the field. The excursions allow to shown the main features of the landscape (rivers, mountains, rocks…) and the impacts of the humankind on the changes of the nature to the students. The program is now 6 years old and it is being very successful with more than 200 hundreds participants and with excursion every two weeks. This paper will show the importance of teaching to students that arrive to the university after retirement. And that trekking is a successful strategy as the students realise that they can be active and see the environmental changes suffered but the the land and the society. During the last 10 years more than 100 excursion were done by the Geograns Project. They were mainly one-day excursion, but sometimes two days excursions and one week excursions are done. The three types of excursions are showing positive acceptance of the students.

  14. Entry Vehicle Control System Design for the Mars Smart Lander

    NASA Technical Reports Server (NTRS)

    Calhoun, Philip C.; Queen, Eric M.

    2002-01-01

    The NASA Langley Research Center, in cooperation with the Jet Propulsion Laboratory, participated in a preliminary design study of the Entry, Descent and Landing phase for the Mars Smart Lander Project. This concept utilizes advances in Guidance, Navigation and Control technology to significantly reduce uncertainty in the vehicle landed location on the Mars surface. A candidate entry vehicle controller based on the Reaction Control System controller for the Apollo Lunar Excursion Module digital autopilot is proposed for use in the entry vehicle attitude control. A slight modification to the phase plane controller is used to reduce jet-firing chattering while maintaining good control response for the Martian entry probe application. The controller performance is demonstrated in a six-degree-of-freedom simulation with representative aerodynamics.

  15. Coaxial Compound Helicopter for Confined Urban Operations

    NASA Technical Reports Server (NTRS)

    Johnson, Wayne; Elmore, Joshua F.; Keen, Ernest B.; Gallaher, Andrew T.; Nunez, Gerardo F.

    2016-01-01

    A rotorcraft was designed for military operations in a confined urban environment. The specifications included major increases in useful load, range, and speed relative current aircraft capabilities, with a size constraint based on the dimensions of urban streets and intersections. Analysis showed that this combination of requirements is best satisfied by a coaxial main-rotor configuration, with lift compounding to off-load the rotors at high speed, and ducted fans under the rotor disk for propulsion. The baseline design is described, and the aircraft performance is summarized for utility, attack, MEDEVAC, and cargo delivery missions. The impact on size and performance is examined for a number of excursions, including lift-offset main rotors. Technology development required to achieve this advance in capability is recommended.

  16. Time-Resolved Quantitative Analysis of the Diaphragms During Tidal Breathing in a Standing Position Using Dynamic Chest Radiography with a Flat Panel Detector System ("Dynamic X-Ray Phrenicography"): Initial Experience in 172 Volunteers.

    PubMed

    Yamada, Yoshitake; Ueyama, Masako; Abe, Takehiko; Araki, Tetsuro; Abe, Takayuki; Nishino, Mizuki; Jinzaki, Masahiro; Hatabu, Hiroto; Kudoh, Shoji

    2017-04-01

    Diaphragmatic motion in a standing position during tidal breathing remains unclear. The purpose of this observational study was to evaluate diaphragmatic motion during tidal breathing in a standing position in a health screening center cohort using dynamic chest radiography in association with participants' demographic characteristics. One hundred seventy-two subjects (103 men; aged 56.3 ± 9.8 years) underwent sequential chest radiographs during tidal breathing using dynamic chest radiography with a flat panel detector system. We evaluated the excursions of and peak motion speeds of the diaphragms. Associations between the excursions and participants' demographics (gender, height, weight, body mass index [BMI], smoking history, tidal volume, vital capacity, and forced expiratory volume) were investigated. The average excursion of the left diaphragm (14.9 ± 4.6 mm, 95% CI 14.2-15.5 mm) was significantly larger than that of the right (11.0 ± 4.0 mm, 95% CI 10.4-11.6 mm) (P <0.001). The peak motion speed of the left diaphragm (inspiratory, 16.6 ± 4.2 mm/s; expiratory, 13.7 ± 4.2 mm/s) was significantly faster than that of the right (inspiratory, 12.4 ± 4.4 mm/s; expiratory, 9.4 ± 3.8 mm/s) (both P <0.001). Both simple and multiple regression models demonstrated that higher BMI and higher tidal volume were associated with increased excursions of the bilateral diaphragm (all P <0.05). The average excursions of the diaphragms are 11.0 mm (right) and 14.9 mm (left) during tidal breathing in a standing position. The diaphragmatic motion of the left is significantly larger and faster than that of the right. Higher BMI and tidal volume are associated with increased excursions of the bilateral diaphragm. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  17. Paleomagnetic Results From the Pleistocene Sediments of Lomonosov Ridge, Central Artic Ocean, IODP Leg 302

    NASA Astrophysics Data System (ADS)

    King, J. W.; Heil, C.; O'Regan, M.; Moran, K.; Gattacecca, J.; Backman, J.; Jakobsson, M.; Moore, T.

    2005-12-01

    Two major conclusions can be drawn from magnetic studies of Pleistocene sediments drilled on Lomonosov Ridge, central Arctic Ocean during IODP Leg 302. The first conclusion is that central Arctic Ocean sedimentation rates approach 2 cm/ka during the Pleistocene, thereby resolving the Arctic sedimentation rate controversy in favor of "fast" rates. The second conclusion is that abundant broad intervals of reversed polarity during the Pleistocene are a consistent characteristic of Arctic sedimentary records. These broad reversed intervals have helped perpetuate the Arctic sedimentation rate controversy. The weight of evidence strongly indicates that these reversal intervals are excursions. They do not occur during the late Brunhes Epoch (approximately 0-250,000 BP), but occur during the mid to lower Brunhes Epoch and persist into the upper Matuyama Epoch. We observe a strong correlation between rock magnetic variations, color changes, and physical property stratigraphy and these excursions. The model for Arctic sedimentation indicates that the excursions primarily occur during "interglacial" intervals. Previous high quality paleomagnetic studies of Bermuda Rise sediments have shown that approximately 85 % of Brunhes age excursions occur during interglacial periods (Lund, et al., 2001). In addition, similar excursions do not appear to occur at high southern latitudes (e.g. Acton, et al., 2002). For these reasons, we feel that hypotheses that attribute the interesting observed Arctic paleomagnetic behavior to environmental controls (e.g. sedimentation processes) are favored over those involving geomagnetic field behavior within the tangent cylinder. Acton, G. D., Guyodo, Y., and S. A. Brachfeld, 2002. Magnetostratigraphy of sediment drifts on the continental rise of West Antarctica (ODP Leg 178, Sites 1095, 1096, and 1101). In Barker, P. F., Camerlenghi, A., Acton, G. D., and Ramsay, A.T.S (Eds.), Proc. ODP Sci. Results, v. 178; 1-61 (CD ROM). Lund, S. P., G. D. Acton, B. Clement, M. Okada, and T. Williams. 2001. Brunhes chron magnetics excursions recovered from Leg 172 sediments. In Keigwin, L. D., Rio, D., Acton, G. D., and Arnold, E., (eds.) Proc. ODP Sci. Results, v. 172; p. 1-18 (Online)

  18. Correlation of aptian-albian carbon isotope excursions in continental strata of the cretaceous Foreland Basin, Eastern Utah, U.S.A.

    USGS Publications Warehouse

    Ludvigson, Greg A.; Joeckel, R.M.; Gonzalez, Luis A.; Gulbranson, E.L.; Rasbury, E.T.; Hunt, G.J.; Kirkland, J.I.; Madsen, S.

    2010-01-01

    Nodular carbonates ("calcretes") in continental foreland-basin strata of the Early Cretaceous Cedar Mountain Formation (CMF) in eastern Utah yield ??13C and ??O records of changes in the exogenic carbon cycle related to oceanic anoxic events (OAEs), and terrestrial paleoclimate. Chemostratigraphic profiles of both forebulge and foredeep sections show two prominent positive ??13C excursions, each with a peak value of -3% VPDB, and having background ??13C values of about -6% VPDB. These excursions correlate with the global early Aptian (Ap7) and late Aptian-early Albian (Apl2-All) carbon isotope excursions. Aptian-Albian positive ??13C excursions in the CMF also correspond to 3-4 per mil increases in carbonate ??18O. These phenomena record local aridification events. The chemostratigraphic profile on the thinner forebulge section of the CMF is calibrated, for the first time, by a radiogenic U-Pb date of 119.4 ?? 2.6 Ma on a carbonate bed, and by detrital zircon U-Pb dates on two bounding sandstone units (maximum depositional ages of 146 Ma and 112 Ma). P??trographie observations and diagenetic analyses of micritic to microsparitic carbonates from nodules indicate palustrine origins and demonstrate that they crystallized in shallow early meteoric phreatic environments. Meteoric calcite lines derived from CMF carbonates have ??18O values ranging between -8.1 to -7.5%o VPDB, supporting an estimate of zonal mean groundwater ??18O of -6% VSMOW for an Aptian-Albian paleolatitude of 34?? N. Furthermore, our two chemostratigraphic profiles exhibit a generally proportionate thinning of correlative strata from the foredeep on to the forebulge, suggesting that there were consistently lower rates of accumulation on the forebulge during the Aptian-Albian. Identification of the global Aptian-Albian ??13C excursions in purely continental strata, as demonstrated in this paper, opens a new avenue of research by identifying specific stratigraphie intervals that record the terrestrial paleoclimatic impacts of perturbations of the global carbon cycle. Copyright ?? 2010, SEPM (Society for Sedimentary Geology).

  19. Sulfur isotope change across the Early Mississippian K-O (Kinderhookian-Osagean) δ13C excursion

    NASA Astrophysics Data System (ADS)

    Maharjan, Dev; Jiang, Ganqing; Peng, Yongbo; Nicholl, Michael J.

    2018-07-01

    Paired carbonate associate sulfate (CAS) sulfur isotopes (δ34SCAS), pyrite sulfur isotopes (δ34SPY) and CAS oxygen isotopes (δ18OCAS) across the Early Mississippian K-O δ13C excursion are documented from two sections of a west-dipping carbonate ramp in the southern Great Basin, western U.S.A. A 4-6‰ positive δ34SCAS anomaly, accompanied by negative shifts in δ34SPY and δ18OCAS, is found within the K-O δ13C excursion. In the section with a broader δ13C excursion, Δ34S (Δ34 S =δ34SCAS-δ34SPY) increases from 15‰ to 45‰ and δ13Ccarb drops from 7‰ to 4‰ at the same stratigraphic interval. If this δ34SCAS anomaly represents a global phenomenon, the large magnitude (4-6‰) and short duration (shorter than that of δ13C) suggest an unusual pyrite burial event that expanded from sediments to the ocean water column. In this scenario, the areal and volumetric expansion of sulfate reduction and pyrite burial was likely triggered by abundantly available organic matter near the peak of the K-O δ13C excursion, during which organic carbon production and burial may have reached a maximum, thus substantially expanding the oxygen minimum zone (OMZ). Numerical simulations suggest that pyrite burial rates 2.5-5 times higher than that of the modern ocean followed by sulfide oxidation are required to produce the observed δ34SCAS anomaly in a sulfate-rich ([SO4] ≥28 mM) Early Mississippian ocean. Alternatively, the sulfur and CAS oxygen isotope anomalies may record local sulfur cycling in a foreland basin where changes in weathering input and bottom-water redox conditions in response to sea-level fall and cooling resulted in isotope changes. In both scenarios (either local or global), the integrated carbon, sulfur, and CAS-oxygen isotope data suggest a much more dynamic sulfur cycle across the K-O δ13C excursion than has been previously suggested.

  20. NASA's Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) In-Field Demonstration at Desert RATS 2010

    NASA Technical Reports Server (NTRS)

    Tri, Terry O.; Kennedy, Kriss J.; Toups, Larry; Gill, Tracy R.; Howe, A. Scott

    2011-01-01

    This paper describes the construction, assembly, subsystem integration, transportation, and field testing operations associated with the Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) and discusses lessons learned. In a one-year period beginning summer 2009, a tightly scheduled design-develop-build process was utilized by a small NASA "tiger team" to produce the functional HDU-PEM prototype in time to participate in the 2010 Desert Research and Technology Studies (Desert RATS) field campaign. The process required the coordination of multiple teams, subcontractors, facility management and safety staff. It also required a well-choreographed material handling and transportation process to deliver the finished product from the NASA-Johnson Space Center facilities to the remote Arizona desert locations of the field test. Significant findings of this paper include the team s greater understanding of the HDU-PEM s many integration issues and the in-field training the team acquired which will enable the implementation of the next-generation of improvements and development of high-fidelity field operations in a harsh environment. The Desert RATS analog environment is being promoted by NASA as an efficient means to design, build, and integrate multiple technologies in a mission architecture context, with the eventual goal of evolving the technologies into robust flight hardware systems. The HDU-PEM in-field demonstration at Desert RATS 2010 provided a validation process for the integration team, which has already begun to retool for the 2011 field tests that require an adapted architecture.

  1. Effect of hamstring flexibility on hip and lumbar spine joint excursions during forward-reaching tasks in participants with and without low back pain.

    PubMed

    Johnson, Erica N; Thomas, James S

    2010-07-01

    To examine the correlation between hamstring flexibility and hip and lumbar spine joint excursions during standardized reaching and forward-bending tasks. Retrospective analysis of data obtained during 2 previous prospective studies that examined kinematics and kinetics during forward-reaching tasks in participants with and without low back pain (LBP). The 2 previous studies were conducted in the Motor Control Lab at Ohio University and the Orthopaedic Ergonomics Laboratory at The Ohio State University. Data from a total of 122 subjects from 2 previous studies: study 1: 86 subjects recovered from an episode of acute LBP (recovered) and study 2 (A.I. McCallum, unpublished data): 18 chronic LBP subjects and 18 healthy-matched controls (healthy). Not applicable. Correlation values between hamstring flexibility as measured by straight leg raise (SLR) and amount of hip and lumbar spine joint excursions used during standardized reaching and forward-bending tasks. No significant correlation was found between hamstring flexibility and hip and lumbar joint excursions during forward-bending tasks in the LBP or recovered groups. The SLR had a significant negative correlation with lumbar spine excursions during reaching tasks to a low target in the healthy group (right SLR: P=.011, left SLR: P=.004). Hamstring flexibility is not strongly related to the amount of lumbar flexion used to perform forward-reaching tasks in participants who have chronic LBP or who have recovered from LBP. More research needs to be conducted to examine the influence of hamstring flexibility on observed movement patterns to further evaluate the efficacy of flexibility training in the rehabilitation of patients with LBP. Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  2. 40Ar/ 39Ar, K-Ar and 230Th- 238U dating of the Laschamp excursion: A radioisotopic tie-point for ice core and climate chronologies

    NASA Astrophysics Data System (ADS)

    Singer, Brad S.; Guillou, Hervé; Jicha, Brian R.; Laj, Carlo; Kissel, Catherine; Beard, Brian L.; Johnson, Clark M.

    2009-08-01

    A brief period of enhanced 10Be flux that straddles the interstadial warm period known as Dansgaard-Oeschger event 10 in Greenland and its counterpart in Antarctica, the Antarctic Isotope Maximum 10 is but one consequence of the weakening of Earth's magnetic field associated with the Laschamp excursion. This 10Be peak measured in the GRIP ice core is dated at 41,250 y b2k (= before year 2000 AD) in the most recent GICC05 age model obtained from the NorthGRIP core via multi-parameter counting of annual layers. Uncertainty in the age of the 10Be peak is, however, no better than ± 1630 y at the 95% confidence level, reflecting accumulated error in identifying annual layers. The age of the Laschamp excursion [Guillou, H., Singer, B.S., Laj, C., Kissel, C., Scaillet, S., Jicha, B., 2004. On the age of the Laschamp geomagnetic excursion. Earth Planet. Sci. Lett. 227, 331-343.] is revised on the basis of new 40Ar/ 39Ar, unspiked K-Ar and 238U- 230Th data from three lava flows in the Massif Central, France, together with the 40Ar/ 39Ar age of a transitionally magnetized lava flow at Auckland, New Zealand. Combined, these data yield an age of 40,700 ± 950 y b2k, where the uncertainty includes both analytical and systematic ( 40K and 230Th decay constant) errors. Taking the radioisotopic age as a calibration tie point suggests that the layer-counting chronologies for the NorthGRIP and GISP2 ice cores are more accurate and precise than previously thought at depths corresponding to the Laschamp excursion.

  3. Agreement Between Visual Assessment and 2-Dimensional Analysis During Jump Landing Among Healthy Female Athletes.

    PubMed

    Rabin, Alon; Einstein, Ofira; Kozol, Zvi

    2018-04-01

      Altered movement patterns, including increased frontal-plane knee movement and decreased sagittal-plane hip and knee movement, have been associated with several knee disorders. Nevertheless, the ability of clinicians to visually detect such altered movement patterns during high-speed athletic tasks is relatively unknown.   To explore the association between visual assessment and 2-dimensional (2D) analysis of frontal-plane knee movement and sagittal-plane hip and knee movement during a jump-landing task among healthy female athletes.   Cross-sectional study.   Gymnasiums of participating volleyball teams.   A total of 39 healthy female volleyball players (age = 21.0 ± 5.2 years, height = 172.0 ± 8.6 cm, mass = 64.2 ± 7.2 kg) from Divisions I and II of the Israeli Volleyball Association.   Frontal-plane knee movement and sagittal-plane hip and knee movement during jump landing were visually rated as good, moderate, or poor based on previously established criteria. Frontal-plane knee excursion and sagittal-plane hip and knee excursions were measured using free motion-analysis software and compared among athletes with different visual ratings of the corresponding movements.   Participants with different visual ratings of frontal-plane knee movement displayed differences in 2D frontal-plane knee excursion ( P < .01), whereas participants with different visual ratings of sagittal-plane hip and knee movement displayed differences in 2D sagittal-plane hip and knee excursions ( P < .01).   Visual ratings of frontal-plane knee movement and sagittal-plane hip and knee movement were associated with differences in the corresponding 2D hip and knee excursions. Visual rating of these movements may serve as an initial screening tool for detecting altered movement patterns during jump landings.

  4. Eyelid reanimation with gold weight implant and tendon sling suspension: evaluation of excursion and velocity using the FACIAL CLIMA system.

    PubMed

    Hontanilla, Bernardo; Marre, Diego

    2013-04-01

    This study aims to analyse the efficacy of static techniques, namely gold weight implant and tendon sling, in the reanimation of the paralytic eyelid. Upper eyelid rehabilitation in terms of excursion and blinking velocity is performed using the automatic motion capture system, FACIAL CLIMA. Seventy-four patients underwent a total of 101 procedures including 58 upper eyelid gold weight implants and 43 lower eyelid tendon suspension with 27 patients undergoing both procedures. The presence of lagophtalmos, eye dryness, corneal ulcer, epiphora and lower lid ptosis/ectropion was assessed preoperatively. The Wilcoxon signed-rank test was used to compare preoperative versus postoperative measurements of upper eyelid excursion and blinking velocity determined with FACIAL CLIMA. Significance was set at p <0.05. FACIAL CLIMA revealed significant improvement of eyelid excursion and velocity of blinking (p < 0.001). Eye dryness improved in 49 patients (90.7%) and corneal ulcer resolved without any further treatment in 12 (85.7%) of those with a gold weight inserted. Implant extrusion was observed in 8.6% of the cases. Of the patients with lower lid tendon suspension, correction of ptosis/ectropion and epiphora was achieved in 93.9% and 91.9% of cases, respectively. In eight patients (18.6%), further surgery was needed to adjust tendon tension. The paralytic upper and lower eyelid can be successfully managed with gold weight implant and tendon suspension. The FACIAL CLIMA system is a reliable method to quantify upper eyelid excursion and blinking velocity and to detect the exact position of the lower eyelid. Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  5. Mandibular kinematic changes after unilateral cross-bite with lateral shift correction.

    PubMed

    Venancio, F; Alarcon, J A; Lenguas, L; Kassem, M; Martin, C

    2014-10-01

    The aim of this randomised prospective study was to evaluate the effects of slow maxillary expansion with expansion plates and Hyrax expanders on the kinematics of the mandible after cross-bite correction. Thirty children (15 boys and 15 girls), aged 7·1-11·8, with unilateral cross-bite and functional shift were divided into two groups: expansion plate (n = 15) and Hyrax expander (n = 15). Thirty children with normal occlusion (14 boys and 16 girls, aged 7·3-11·6) served as control group. The maximum vertical opening, lateral mandibular shift (from maximum vertical opening to maximum intercuspation, from rest position to maximum intercuspation and from maximum vertical opening to rest position) and lateral excursions were recorded before and 4 months after treatment. After treatment, the expansion plate group showed a greater lateral shift from rest position to maximum intercuspation than did the control group. The expansion plate patients also presented greater left/contralateral excursion than did the control group. Comparisons of changes after treatment in the cross-bite groups showed significant decreases in the lateral shift from the maximum vertical opening to maximum intercuspation and from the maximum vertical opening to rest position, a significant increase in the homolateral excursion and a significant decrease in the contralateral excursion in the Hyrax expander group, whereas no significant differences were found in the expansion plate group. In conclusion, the Hyrax expander showed better results than did the expansion plate. The Hyrax expander with acrylic occlusal covering significantly improved the mandibular lateral shift and normalised the range of lateral excursion. © 2014 John Wiley & Sons Ltd.

  6. Tonic Investigation Concept of Cervico-vestibular Muscle Afferents

    PubMed Central

    Dorn, Linda Josephine; Lappat, Annabelle; Neuhuber, Winfried; Scherer, Hans; Olze, Heidi; Hölzl, Matthias

    2016-01-01

    Introduction Interdisciplinary research has contributed greatly to an improved understanding of the vestibular system. To date, however, very little research has focused on the vestibular system's somatosensory afferents. To ensure the diagnostic quality of vestibular somatosensory afferent data, especially the extra cranial afferents, stimulation of the vestibular balance system has to be precluded. Objective Sophisticated movements require intra- and extra cranial vestibular receptors. The study's objective is to evaluate an investigation concept for cervico-vestibular afferents with respect to clinical feasibility. Methods A dedicated chair was constructed, permitting three-dimensional trunk excursions, during which the volunteer's head remains fixed. Whether or not a cervicotonic provocation nystagmus (c-PN) can be induced with static trunk excursion is to be evaluated and if this can be influenced by cervical monophasic transcutaneous electrical nerve stimulation (c-TENS) with a randomized test group. 3D-video-oculography (VOG) was used to record any change in cervico-ocular examination parameters. The occurring nystagmuses were evaluated visually due to the small caliber of nystagmus amplitudes in healthy volunteers. Results The results demonstrate: no influence of placebo-controlled c-TENS on the spontaneous nystagmus; a significant increase of the vertical nystagmus on the 3D-trunk-excursion chair in static trunk flexion with cervical provocation in all young healthy volunteers (n = 49); and a significant difference between vertical and horizontal nystagmuses during static trunk excursion after placebo-controlled c-TENS, except for the horizontal nystagmus during trunk torsion. Conclusion We hope this cervicotonic investigation concept on the 3D trunk-excursion chair will contribute to new diagnostic and therapeutic perspectives on cervical pathologies in vestibular head-to-trunk alignment. PMID:28050208

  7. Dosimetric Considerations in Respiratory-Gated Deep Inspiration Breath-Hold for Left Breast Irradiation.

    PubMed

    Walston, Steve; Quick, Allison M; Kuhn, Karla; Rong, Yi

    2017-02-01

    To present our clinical workflow of incorporating AlignRT for left breast deep inspiration breath-hold treatments and the dosimetric considerations with the deep inspiration breath-hold protocol. Patients with stage I to III left-sided breast cancer who underwent lumpectomy or mastectomy were considered candidates for deep inspiration breath-hold technique for their external beam radiation therapy. Treatment plans were created on both free-breathing and deep inspiration breath-hold computed tomography for each patient to determine whether deep inspiration breath-hold was beneficial based on dosimetric comparison. The AlignRT system was used for patient setup and monitoring. Dosimetric measurements and their correlation with chest wall excursion and increase in left lung volume were studied for free-breathing and deep inspiration breath-hold plans. Deep inspiration breath-hold plans had significantly increased chest wall excursion when compared with free breathing. This change in geometry resulted in reduced mean and maximum heart dose but did not impact lung V 20 or mean dose. The correlation between chest wall excursion and absolute reduction in heart or lung dose was found to be nonsignificant, but correlation between left lung volume and heart dose showed a linear association. It was also identified that higher levels of chest wall excursion may paradoxically increase heart or lung dose. Reduction in heart dose can be achieved for many left-sided breast and chest wall patients using deep inspiration breath-hold. Chest wall excursion as well as left lung volume did not correlate with reduction in heart dose, and it remains to be determined what metric will provide the most optimal and reliable dosimetric advantage.

  8. Multiple High-Frequency Carbon Isotope Excursions Across the Precambrian-Cambrian Boundary: Implications for Correlations and Environmental Change

    NASA Astrophysics Data System (ADS)

    Smith, E. F.; Macdonald, F. A.; Schrag, D. P.; Laakso, T.

    2014-12-01

    The GSSP Precambrian-Cambrian boundary in Newfoundland is defined by the first appearance datum (FAD) of Treptichnus pedum, which is considered to be roughly coincident with the FAD of small shelly fossils (SSFs) and a large negative carbon isotope excursion. An association between the FAD of T. pedum and a negative carbon isotope excursion has previously been documented in Northwest Canada (Narbonne et al., 1994) and Death Valley (Corsetti and Hagadorn, 2000), and since then has been used as an chronostratigraphic marker of the boundary, particularly in siliciclastic poor sections that do not preserve T. pedum. Here we present new high-resolution carbon isotope (δ13C ) chemostratigraphy from multiple sections in western Mongolia and the western United States that span the Ediacaran-Cambrian transition. High-resolution sampling (0.2-1 m) reveals that instead of one large negative excursion, there are multiple, high-frequency negative excursions with an overall negative trend during the latest Ediacaran. These data help to more precisely calibrate changes in the carbon cycle across the boundary as well as to highlight the potential problem of identifying the boundary with just a few negative δ13C values. We then use a simple carbon isotope box model to explore relationships between phosphorous delivery to the ocean, oxygenation, alkalinity, and turnovers in carbonate secreting organisms. Corsetti, F.A., and Hagadorn, J.W., 2000, Precambrian-Cambrian transition: Death Valley, United States: Geology, v. 28, no. 4, p. 299-302. Narbonne, G.M., Kaufman, A.J., and Knoll, A.H., 1994, Integrated chemostratigraphy and biostratigraphy of the Windermere Supergroup, northwestern Canada: Implications for Neoproterozoic correlations and the early evolution of animals: Geological Society of America Bulletin, v. 106, no. 10, p. 1281-1292.

  9. Bilateral Improvements in Lower Extremity Function After Unilateral Balance Training in Individuals With Chronic Ankle Instability

    PubMed Central

    Hale, Sheri A.; Fergus, Andrea; Axmacher, Rachel; Kiser, Kimberly

    2014-01-01

    Context: Bilateral improvements in postural control have been reported among individuals with acute lateral ankle sprains and individuals with chronic ankle instability (CAI) when only the unstable ankle is rehabilitated. We do not know if training the stable ankle will improve function on the unstable side. Objective: To explore the effects of a unilateral balance-training program on bilateral lower extremity balance and function in individuals with CAI when only the stable limb is trained. Design: Cohort study. Setting: University clinical research laboratory. Patients or Other Participants: A total of 34 volunteers (8 men, 26 women; age = 24.32 ± 4.95 years, height = 167.01 ± 9.45 cm, mass = 77.54 ± 23.76 kg) with CAI were assigned to the rehabilitation (n = 17) or control (n = 17) group. Of those, 27 (13 rehabilitation group, 14 control group) completed the study. Intervention(s): Balance training twice weekly for 4 weeks. Main Outcome Measure(s): Foot and Ankle Disability Index (FADI), FADI Sport (FADI-S), Star Excursion Balance Test, and Balance Error Scoring System. Results: The rehabilitation and control groups differed in changes in FADI-S and Star Excursion Balance Test scores over time. Only the rehabilitation group improved in the FADI-S and in the posteromedial and anterior reaches of the Star Excursion Balance Test. Both groups demonstrated improvements in posterolateral reach; however, the rehabilitation group demonstrated greater improvement than the control group. When the groups were combined, participants reported improvements in FADI and FADI-S scores for the unstable ankle but not the stable ankle. Conclusions: Our data suggest training the stable ankle may result in improvements in balance and lower extremity function in the unstable ankle. This further supports the existence of a centrally mediated mechanism in the development of postural-control deficits after injury, as well as improved postural control after rehabilitation. PMID:24568231

  10. Response to Tendon Vibration Questions the Underlying Rationale of Proprioceptive Training.

    PubMed

    Lubetzky, Anat Vilnai; McCoy, Sarah Westcott; Price, Robert; Kartin, Deborah

    2017-02-01

    Proprioceptive training on compliant surfaces is used to rehabilitate and prevent ankle sprains. The ability to improve proprioceptive function via such training has been questioned. Achilles tendon vibration is used in motor-control research as a form of proprioceptive stimulus. Using measures of postural steadiness with nonlinear measures to elucidate control mechanisms, tendon vibration can be applied to investigate the underlying rationale of proprioceptive training. To test whether the effect of vibration on young adults' postural control depended on the support surface. Descriptive laboratory study. Research laboratory. Thirty healthy adults and 10 adults with chronic ankle instability (CAI; age range = 18-40 years). With eyes open, participants stood in bilateral stance on a rigid plate (floor), memory foam, and a Both Sides Up (BOSU) ball covering a force platform. We applied bilateral Achilles tendon vibration for the middle 20 seconds in a series of 60-second trials and analyzed participants' responses from previbration to vibration (pre-vib) and from vibration to postvibration (vib-post). We calculated anterior-posterior excursion of the center of pressure and complexity index derived from the area under multiscale entropy curves. The excursion response to vibration differed by surface, as indicated by a significant interaction of P < .001 for the healthy group at both time points and for the CAI group vib-post. Although both groups demonstrated increased excursion from pre-vib and from vib-post, a decrease was observed on the BOSU. The complexity response to vibration differed by surface for the healthy group (pre-vib, P < .001). The pattern for the CAI group was similar but not significant. Complexity changes vib-post were the same on all surfaces for both groups. Participants reacted less to ankle vibration when standing on the BOSU as compared with the floor, suggesting that proprioceptive training may not be occurring. Different balance-training paradigms to target proprioception, including tendon vibration, should be explored.

  11. Orthotic intervention in forefoot and rearfoot strike running patterns.

    PubMed

    Stackhouse, Carrie Laughton; Davis, Irene McClay; Hamill, Joseph

    2004-01-01

    To compare the differential effect of custom orthoses on the lower extremity mechanics of a forefoot and rearfoot strike pattern. Fifteen subjects ran with both a forefoot and a rearfoot strike pattern with and without orthoses. Lower extremity kinematic and kinetic variables were compared between strike pattern and orthotic conditions. Foot orthoses have been shown to be effective in controlling excessive rearfoot motion in rearfoot strikers. The effect of orthotic intervention on rearfoot motion in forefoot strikers has not been previously reported. Five trials were collected for each condition. Peak rearfoot eversion, eversion excursion, eversion velocity, peak inversion moment, and inversion work were compared between conditions. Kinematic variables in the sagittal plane of the rearfoot and in the frontal and sagittal plane of the knee were also determined. Increased rearfoot excursions and velocities and decreased peak eversion were noted in the forefoot strike pattern compared to the rearfoot strike pattern. Orthotic intervention, however,did not significantly change rearfoot motion in either strike pattern. Reductions in internal rotation and abduction of the knee were noted with orthotic intervention. Foot orthoses do not differentially effect rearfoot motion of a rearfoot strike and a forefoot strike running pattern. Orthotic intervention has a larger and more systematic effect on rearfoot kinetics compared to rearfoot kinematics.

  12. Sulfur record of rising and falling marine oxygen and sulfate levels during the Lomagundi event.

    PubMed

    Planavsky, Noah J; Bekker, Andrey; Hofmann, Axel; Owens, Jeremy D; Lyons, Timothy W

    2012-11-06

    Carbonates from approximately 2.3-2.1 billion years ago show markedly positive δ(13)C values commonly reaching and sometimes exceeding +10‰. Traditional interpretation of these positive δ(13)C values favors greatly enhanced organic carbon burial on a global scale, although other researchers have invoked widespread methanogenesis within the sediments. To resolve between these competing models and, more generally, among the mechanisms behind Earth's most dramatic carbon isotope event, we obtained coupled stable isotope data for carbonate carbon and carbonate-associated sulfate (CAS). CAS from the Lomagundi interval shows a narrow range of δ(34)S values and concentrations much like those of Phanerozoic and modern marine carbonate rocks. The δ(34)S values are a close match to those of coeval sulfate evaporites and likely reflect seawater composition. These observations are inconsistent with the idea of diagenetic carbonate formation in the methanic zone. Toward the end of the carbon isotope excursion there is an increase in the δ(34)S values of CAS. We propose that these trends in C and S isotope values track the isotopic evolution of seawater sulfate and reflect an increase in pyrite burial and a crash in the marine sulfate reservoir during ocean deoxygenation in the waning stages of the positive carbon isotope excursion.

  13. Evaluation of Data-Logging Transducer to Passively Collect Pressure Vessel p/T History

    NASA Technical Reports Server (NTRS)

    Wnuk, Stephen P.; Le, Son; Loew, Raymond A.

    2013-01-01

    Pressure vessels owned and operated by NASA are required to be regularly certified per agency policy. Certification requires an assessment of damage mechanisms and an estimation of vessel remaining life. Since detail service histories are not typically available for most pressure vessels, a conservative estimate of vessel pressure/temperature excursions is typically used in assessing fatigue life. This paper details trial use of a data-logging transducer to passively obtain actual pressure and temperature service histories of pressure vessels. The approach was found to have some potential for cost savings and other benefits in certain cases.

  14. Entry Dispersion Analysis for the Stardust Comet Sample Return Capsule

    NASA Technical Reports Server (NTRS)

    Desai, Prasun N.; Mitcheltree, Robert A.; Cheatwood, F. McNeil

    1997-01-01

    Stardust will be the first mission to return samples from beyond the Earth-Moon system. The sample return capsule, which is passively controlled during the fastest Earth entry ever, will land by parachute in Utah. The present study analyzes the entry, descent, and landing of the returning sample capsule. The effects of two aerodynamic instabilities are revealed (one in the high altitude free molecular regime and the other in the transonic/subsonic flow regime). These instabilities could lead to unacceptably large excursions in the angle-of-attack near peak heating and main parachute deployment, respectively. To reduce the excursions resulting from the high altitude instability, the entry spin rate of the capsule is increased. To stabilize the excursions from the transonic/subsonic instability, a drogue chute with deployment triggered by an accelerometer and timer is added prior to main parachute deployment. A Monte Carlo dispersion analysis of the modified entry (from which the impact of off-nominal conditions during the entry is ascertained) shows that the capsule attitude excursions near peak heating and drogue chute deployment are within Stardust program limits. Additionally, the size of the resulting 3-sigma landing ellipse is 83.5 km in downrange by 29.2 km in crossrange, which is within the Utah Test and Training Range boundaries.

  15. Recognizing the Albian-Cenomanian (OAE1d) sequence boundary using plant carbon isotopes: Dakota Formation, Western Interior Basin, USA

    USGS Publications Warehouse

    Grocke, D.R.; Ludvigson, Greg A.; Witzke, B.L.; Robinson, S.A.; Joeckel, R.M.; Ufnar, David F.; Ravn, R.L.

    2006-01-01

    Analysis of bulk sedimentary organic matter and charcoal from an Albian-Cenomanian fluvial-estuarine succession (Dakota Formation) at Rose Creek Pit (RCP), Nebraska, reveals a negative excursion of ???3???, in late Albian strata. Overlying Cenomanian strata have ??13C values of -24???, to -23???, that are similar to pre-excursion values. The absence of an intervening positive excursion (as exists in marine records of the Albian-Cenomanian boundary) likely results from a depositional hiatus. The corresponding positive ??13C event and proposed depositional hiatus are concordant with a regionally identified sequence boundary in the Dakota Formation (D2), as well as a major regressive phase throughout the globe at the Albian-Cenomanian boundary. Data from RCP confirm suggestions that some positive carbon-isotope excursions in the geologic record are coincident with regressive sea-level phases. We estimate using isotopic correlation that the D2 sequence boundary at RCP was on the order of 0.5 m.y. in duration. Therefore, interpretations of isotopic events and associated environmental phenomena, such as oceanic anoxic events, in the shallow-marine and terrestrial record may be influenced by stratigraphic incompleteness. Further investigation of terrestrial ??13C records may be useful in recognizing and constraining sea-level changes in the geologic record. ?? 2006 Geological Society of America.

  16. The Laschamp geomagnetic excursion featured in nitrate record from EPICA-Dome C ice core

    PubMed Central

    Traversi, R.; Becagli, S.; Poluianov, S.; Severi, M.; Solanki, S. K.; Usoskin, I. G.; Udisti, R.

    2016-01-01

    Here we present the first direct comparison of cosmogenic 10Be and chemical species in the period of 38–45.5 kyr BP spanning the Laschamp geomagnetic excursion from the EPICA-Dome C ice core. A principal component analysis (PCA) allowed to group different components as a function of the main sources, transport and deposition processes affecting the atmospheric aerosol at Dome C. Moreover, a wavelet analysis highlighted the high coherence and in-phase relationship between 10Be and nitrate at this time. The evident preferential association of 10Be with nitrate rather than with other chemical species was ascribed to the presence of a distinct source, here labelled as “cosmogenic”. Both the PCA and wavelet analyses ruled out a significant role of calcium in driving the 10Be and nitrate relationship, which is particularly relevant for a plateau site such as Dome C, especially in the glacial period during which the Laschamp excursion took place. The evidence that the nitrate record from the EDC ice core is able to capture the Laschamp event hints toward the possibility of using this marker for studying galactic cosmic ray flux variations and thus also major geomagnetic field excursions at pluri-centennial-millennial time scales, thus opening up new perspectives in paleoclimatic studies. PMID:26819064

  17. Extreme 13Ccarb enrichment in ca. 2.0 Ga magnesite-stromatolite-dolomite-`red beds' association in a global context: a case for the world-wide signal enhanced by a local environment

    NASA Astrophysics Data System (ADS)

    Melezhik, Victor A.; Fallick, Anthony E.; Medvedev, Pavel V.; Makarikhin, Vladimir V.

    1999-12-01

    The Palaeoproterozoic positive excursion of δ 13Ccarb is now considered as three positive shifts of δ 13Ccarb separated by returns to 0‰, which all occurred between 2.40 and 2.06 Ma. This isotopic event is unique in terms of both duration (>300 Ma) and 13C enrichment (up to +18‰). The mechanism responsible for one of the most significant carbon isotopic shifts in Earth history remains highly debatable. To date, δ 13C of +10‰ to +15‰ cannot be balanced by organic carbon burial ( forg) as there is no geological evidence for an enhanced C org accumulation prior to or synchronous with the excursion. Instead, termination of these excursions is followed by formation of a vast reservoir of 13C-depleted organic material (-45‰ at Shunga) and by one of the earliest known oil-generation episodes at 2.0 Ga. None of the three positive excursions of δ 13Ccarb is followed by a negative isotopic shift significantly below 0‰, as has always been observed in younger isotopic events, reflecting an overturn of a major marine carbon reservoirs. This may indicate that forg was constant: implying that the mechanism involved in the production of C org was different. Onset of intensive methane cycling resulting in Δc change is another possibility. The majority of sampled 13Ccarb-rich localities represents shallow-water stromatolitic dolostones, `red beds' and evaporites formed in restricted intracratonic basins, and may not reflect global δ 13Ccarb values. Closely spaced drill core samples ( n=73) of stromatolitic dolostones from the >1980±27 Ma Tulomozerskaya Formation in the Onega palaeobasin, Russian Karelia, have been analysed for δ 13Ccarb and δ 18Ocarb in order to demonstrate that different processes were involved in the formation of 13Ccarb-rich carbonates. The 800 m-thick magnesite-stromatolite-dolomite-`red beds' succession formed in a complex combination of environments on the Karelian craton: peritidal shallow marine, low-energy protected bights, barred basins, evaporative ephemeral ponds, coastal sabkhas and playa lakes. The carbonate rocks exhibit extreme 13C enrichment with δ 13C values ranging from +5.7 to +17.2‰ vs. V-PDB (mean+9.9±2.3‰) and δ 18O from 18.6 to 26.0‰ vs. V-SMOW (mean 22.0±1.6‰). The Tulomozerskaya isotopic excursion is characteristic of the global 2.4-2.06 Ga positive shifts of carbonate 13C/ 12C, although it reveals the greatest enrichment in 13C known from this interval. An external basin(s) is considered to have provided an enhanced C org burial and global seawater enrichment in 13C: the global background value for the isotopic shift at Tulomozero time (ca. 2.0 Ga) is roughly estimated at around +5‰. An explosion of stromatolite-forming microbial communities in shallow-water basins, evaporative and partly restricted environments, high bioproductivity, enhanced uptake of 12C, and pene-contemporaneous recycling of organic material in cyanobacterial mats with the production and consequent loss of CO 2 (and CH 4?) are believed to be additional local factors which may have enhanced δ 13C from +5‰ up to +17‰. Such factors should be taken into account when interpreting carbon isotopic data and attempting to discriminate between the local enrichment in 13C and globally enhanced δ 13C values. We propose that many previously reported δ 13C values from other localities, where environmental interpretations are not available or have not been taken into account may not represent the global δ 13C values.

  18. Outpacing the Anthropocene: New Constraints for the Rate of Carbon Release at the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Wright, J. D.; Schaller, M. F.

    2012-12-01

    The Paleocene/Eocene Thermal Maximum (PETM) Carbon Isotope Excursion (CIE) is linked to benthic foraminiferal extinction and excursion taxa in planktonic foraminifera and calcareous nannofossils. Previous studies have used integrated bio-magneto-stratigraphies, cycle counting, and extraterrestrial 3He accumulation rates to produce a range of estimates for the duration of the initial onset of the PETM CIE between 750 years to 30 kyr. Durations for the total release time (onset to initiation of recovery) range from 45 to 95 kyr. Uncertainty in the timing of the onset of the PETM CIE prevents the identification of a causal mechanism, and hence understanding the biological responses. Recent work on the Paleocene/Eocene Marlboro Clay has unveiled the presence of regular couplets (~2 cm) expressed in multiple cores and exposures throughout the Atlantic Coastal Plain. Specifically, the Millville and newly recovered Wilson Lake B cores contain 750 and 660 layers through the CIE, respectively. These couplets have corresponding oxygen stable isotope cycles, arguing for a climatic origin. Orbital and millennial periodicities are far too long to explain the ~750 layers identified in the Millville core. Seasonal insolation is the only regular climate cycle that can plausibly account for the observed δ18O amplitudes (~1‰, with some cycles up to 2‰) and layer counts. Seasonal freshwater input can also augment the cyclic oscillations in δ18O, but the majority of the variability is most plausibly ascribed to temperature. Wilson Lake B and Millville have total δ13C excursions of -5 and -4.5‰ respectively, as well as highly expanded sections of the PETM CIE. In the Millville core, high-resolution, bulk stable isotope records show a 3.5‰ δ13C decrease over 12 layers across the PETM CIE onset. Concomitant with this δ13C decrease is a sharp drop in CaCO3. Decreases in both proxies require a large, sudden release of isotopically light carbon. The couplet chronology indicates that the carbon released during the CIE consisted of a large, nearly instantaneous initial burst, followed by a protracted lower-level release lasting approximately 500 years. Such a scenario is most consistent with the release of thermogenic carbon due to LIP emplacement, or a comet impact. Under this release schedule, excursion planktonic foraminiferal and nannofossil taxa represent morphologic adaptation to the high CO2, low pH conditions rather than evolutionary changes.

  19. Counteracting moment device for reduction of earthquake-induced excursions of multi-level buildings.

    PubMed

    Nagaya, K; Fukushima, T; Kosugi, Y

    1999-05-01

    A vibration-control mechanism for beams and columns was presented in our previous report in which the earthquake force was transformed into a vibration-control force by using a gear train mechanism. In our previous report, however, only the principle of transforming the earthquake force into the control force was presented; the discussion for real structures and the design method were not presented. The present article provides a theoretical analysis of the column which is used in multi-layered buildings. Experimental tests were carried out for a model of multi-layered buildings in the frequency range of a principal earthquake wave. Theoretical results are compared to the experimental data. The optimal design of the control mechanism, which is of importance in the column design, is presented. Numerical calculations are carried out for the optimal design. It is shown that vibrations of the column involving the mechanism are suppressed remarkably. The optimal design method and the analytical results are applicable to the design of the column.

  20. Technologies for Continuous Glucose Monitoring: Current Problems and Future Promises

    PubMed Central

    Vaddiraju, Santhisagar; Burgess, Diane J; Tomazos, Ioannis; Jain, Faquir C; Papadimitrakopoulos, Fotios

    2010-01-01

    Devices for continuous glucose monitoring (CGM) are currently a major focus of research in the area of diabetes management. It is envisioned that such devices will have the ability to alert a diabetes patient (or the parent or medical care giver of a diabetes patient) of impending hypoglycemic/hyperglycemic events and thereby enable the patient to avoid extreme hypoglycemic/hyperglycemic excursions as well as minimize deviations outside the normal glucose range, thus preventing both life-threatening events and the debilitating complications associated with diabetes. It is anticipated that CGM devices will utilize constant feedback of analytical information from a glucose sensor to activate an insulin delivery pump, thereby ultimately realizing the concept of an artificial pancreas. Depending on whether the CGM device penetrates/breaks the skin and/or the sample is measured extracorporeally, these devices can be categorized as totally invasive, minimally invasive, and noninvasive. In addition, CGM devices are further classified according to the transduction mechanisms used for glucose sensing (i.e., electrochemical, optical, and piezoelectric). However, at present, most of these technologies are plagued by a variety of issues that affect their accuracy and long-term performance. This article presents a critical comparison of existing CGM technologies, highlighting critical issues of device accuracy, foreign body response, calibration, and miniaturization. An outlook on future developments with an emphasis on long-term reliability and performance is also presented. PMID:21129353

  1. Using n-alkane records to constrain carbon cycle - hydrological cycle coupling: Case study from the Northern Hemisphere mid-latitudes during the PETM

    NASA Astrophysics Data System (ADS)

    Krishnan, S.; Pagani, M.; Tipple, B. J.

    2010-12-01

    The early Eocene was a warmer world compared to the present and is characterized by rising temperatures interspersed with rapid hyperthermal events. During the largest of these rapid warming events; the Paleocene-Eocene Thermal Maximum (PETM), proxy records suggest that sea surface temperatures (SST) rose by 3-5 deg. C in the tropics (Zachos et al., 2003, Tripati and Elderfield, 2004), >5 deg. C in the Arctic (Sluijs et al., 2006) and perhaps has high as 9 deg. C in some sub-Antarctic regions (Kennett and Stott, 1991; Thomas et al., 1999). This warming is believed to be the result of massive input of 13C-depleted carbon into the ocean-atmosphere system, evidenced by the large negative carbon isotope excursion (CIE) and carbonate dissolution associated with the event. However, there are several questions regarding the exact mechanism of warming and feedbacks between the carbon cycle and climate. Did climate shift prior to the main event that led to the release of isotopically light carbon? Do we observe consistent leads or lags between changes in carbon isotopes and hydrological conditions during warm intervals? This study aims to reconstruct hydrological changes in the in the Northern Hemisphere mid-latitudes during the PETM using terrestrial biomarkers. Terrestrial biomarkers, such leaf-wax lipids stored in sediments, have the unique advantage of recording carbon and hydrogen isotopic compositions of atmospheric CO2 (modified by plant fractionation) and precipitation (modified by plant fractionation and evapotranspiration), allowing evaluation of the relative timing of carbon and hydrogen isotopic (i.e., climate) shifts. In this study, we compile and present three mid-latitude PETM records from the Northern Hemisphere, i.e. Alamedilla (Spain), Cicogna and Forada (Italy). The Cicogna and Forada sections are located in the Belluno basin (~12 km apart). Preliminary results do not indicate any significant pre-excursion hydrogen isotope changes at Cicogna, while at Forada we observe a pre-excursion shift toward more positive values. Comparison of the mean-weighted isotopic trends (to account for vegetation changes) indicates that the carbon and hydrogen isotopic compositions shift simultaneously at the start of the CIE at Cicogna and Forada and remain coupled during the latter part of the recovery. However, the most depleted values in δD do not coincide with the most negative δ13C values, suggesting that the response time of the hydrological cycle was slower than the carbon isotopic excursion. The δD trends appear to diverge from δ13C records during the initial recovery period. This difference in response and response times between the initial perturbation and recovery enable us to constrain the timing and mechanism of feedbacks. A third section (Alamedilla), located at lower latitude, will be used to test these hypotheses. The timing and average magnitudes of δD changes at these three sites will be extrapolated to infer precipitation trends during the late Paleocene, peak PETM, and early Eocene for this region and will be useful for future data-model comparisons.

  2. TECHNICAL REVIEW OF ZPR-I ACCIDENTAL TRANSIENT--THE POWER EXCURSION, EXPOSURES, AND CLINICAL DATA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brittan, R. O.; Hasterlik, R. J.; Marinelli, L. D.

    1953-01-26

    On June 2. 1952. a large reactivity change was made manually in a ZPR-1 assembly causing a power excursion of about one kwh, which resulted in damage to the reactor core components and radiation exposure of some of the operating personnel to perhaps several hundred rep. A description is presented of the incident, estimates are made of the exposures, and early clinical data are summarized. (C.H.)

  3. Working and Learning in a Field Excursion.

    PubMed

    Hole, Torstein Nielsen

    2018-06-01

    This study aimed to discern sociocultural processes through which students learn in field excursions. To achieve this aim, short-term ethnographic techniques were employed to examine how undergraduate students work and enact knowledge (or knowing) during a specific field excursion in biology. The students participated in a working practice that employed research methods and came to engage with various biological phenomena over the course of their work. A three-level analysis of the students' experiences focused on three processes that emerged: participatory appropriation, guided participation, and apprenticeship. These processes derive from advances in practice-oriented theories of knowing. Through their work in the field, the students were able to enact science autonomously; they engaged with peers and teachers in specific ways and developed new understandings about research and epistemology founded on their experiences in the field. Further discussion about the use of "practice" and "work" as analytical concepts in science education is also included.

  4. A Vendian-Cambrian boundary succession from the northwestern margin of the Siberian Platform: stratigraphy, palaeontology, chemostratigraphy and correlation

    NASA Technical Reports Server (NTRS)

    Bartley, J. K.; Pope, M.; Knoll, A. H.; Semikhatov, M. A.; Grotzinger, J. (Principal Investigator)

    1998-01-01

    Siberia contains several key reference sections for studies of biological and environmental evolution across the Proterozoic-Phanerozoic transition. The Platonovskaya Formation, exposed in the Turukhansk region of western Siberia, is an uppermost Proterozoic to Cambrian succession whose trace and body fossils place broad limits on the age of deposition, but do not permit detailed correlation with boundary successions elsewhere. In contrast, a striking negative carbon isotopic excursion in the lower part of the Platonovskaya Formation permits precise chemostratigraphic correlation with upper-most Yudomian successions in Siberia, and possibly worldwide. In addition to providing a tool for correlation, the isotopic excursion preserved in the Platonovskaya and contemporaneous successions documents a major biogeochemical event, likely involving the world ocean. The excursion coincides with the palaeontological breakpoint between Ediacaran- and Cambrian-style assemblages, suggesting a role for biogeochemical change in evolutionary events near the Proterozoic Cambrian boundary.

  5. A Vendian-Cambrian boundary succession from the northwestern margin of the Siberian Platform: stratigraphy, palaeontology, chemostratigraphy and correlation.

    PubMed

    Bartley, J K; Pope, M; Knoll, A H; Semikhatov, M A; Petrov PYu

    1998-07-01

    Siberia contains several key reference sections for studies of biological and environmental evolution across the Proterozoic-Phanerozoic transition. The Platonovskaya Formation, exposed in the Turukhansk region of western Siberia, is an uppermost Proterozoic to Cambrian succession whose trace and body fossils place broad limits on the age of deposition, but do not permit detailed correlation with boundary successions elsewhere. In contrast, a striking negative carbon isotopic excursion in the lower part of the Platonovskaya Formation permits precise chemostratigraphic correlation with upper-most Yudomian successions in Siberia, and possibly worldwide. In addition to providing a tool for correlation, the isotopic excursion preserved in the Platonovskaya and contemporaneous successions documents a major biogeochemical event, likely involving the world ocean. The excursion coincides with the palaeontological breakpoint between Ediacaran- and Cambrian-style assemblages, suggesting a role for biogeochemical change in evolutionary events near the Proterozoic Cambrian boundary.

  6. Bounded excursion stable gravastars and black holes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rocha, P; Miguelote, A Y; Chan, R

    2008-06-15

    Dynamical models of prototype gravastars were constructed in order to study their stability. The models are the Visser-Wiltshire three-layer gravastars, in which an infinitely thin spherical shell of stiff fluid divides the whole spacetime into two regions, where the internal region is de Sitter, and the external one is Schwarzschild. It is found that in some cases the models represent the 'bounded excursion' stable gravastars, where the thin shell is oscillating between two finite radii, while in other cases they collapse until the formation of black holes occurs. In the phase space, the region for the 'bounded excursion' gravastars ismore » very small in comparison to that of black holes, but not empty. Therefore, although the possibility of the existence of gravastars cannot be excluded from such dynamical models, our results indicate that, even if gravastars do indeed exist, that does not exclude the possibility of the existence of black holes.« less

  7. Characterization of the mechanical properties of backpacks and their influence on the energetics of walking.

    PubMed

    Foissac, Matthieu; Millet, Guillaume Y; Geyssant, André; Freychat, Philippe; Belli, Alain

    2009-01-19

    The objectives of the experiment were (i) to characterize the mechanical properties of backpacks and (ii) to study the influence of a flexible backpack on the energetics and kinematics of walking. Twelve subjects walked at different speeds on a treadmill with each of two backpacks loaded with 25% bodyweight, with either a rigid or a flexible link between the body attachment and the suspended loads. A single degree of freedom linear model of the link between the pack and the trunk was used to calculate the stiffness and damping coefficient of the two backpacks. The oxygen consumption (VO2) and the vertical acceleration of both the backpack and trunk were measured. The vertical excursion of the pack given by the model was significantly correlated with that actually measured (R=0.87, p<0.001). At 3.7 and 4.5 km h(-1) the flexible pack induced lower acceleration peaks (respectively -22% and -8%; p<0.05) and tended to reduce VO2 (p=0.055 at 4.5 km h(-1)) compared with the rigid one. At 5.2 and 6 km h(-1) both the accelerative forces and VO2 increased with the flexible pack (p<0.05) mainly because of the high vertical movement of the pack. It was concluded that a simple model can be used to predict the vertical excursion of the pack and that a flexible backpack can provide energetic benefits when its oscillations are nearly in phase with those of the trunk. However, any resonance effect can lead to a modified walking pattern and an increased metabolic cost.

  8. Assessing the record and causes of Late Triassic extinctions

    USGS Publications Warehouse

    Tanner, L.H.; Lucas, S.G.; Chapman, M.G.

    2004-01-01

    Accelerated biotic turnover during the Late Triassic has led to the perception of an end-Triassic mass extinction event, now regarded as one of the "big five" extinctions. Close examination of the fossil record reveals that many groups thought to be affected severely by this event, such as ammonoids, bivalves and conodonts, instead were in decline throughout the Late Triassic, and that other groups were relatively unaffected or subject to only regional effects. Explanations for the biotic turnover have included both gradualistic and catastrophic mechanisms. Regression during the Rhaetian, with consequent habitat loss, is compatible with the disappearance of some marine faunal groups, but may be regional, not global in scale, and cannot explain apparent synchronous decline in the terrestrial realm. Gradual, widespread aridification of the Pangaean supercontinent could explain a decline in terrestrial diversity during the Late Triassic. Although evidence for an impact precisely at the boundary is lacking, the presence of impact structures with Late Triassic ages suggests the possibility of bolide impact-induced environmental degradation prior to the end-Triassic. Widespread eruptions of flood basalts of the Central Atlantic Magmatic Province (CAMP) were synchronous with or slightly postdate the system boundary; emissions of CO2 and SO2 during these eruptions were substantial, but the contradictory evidence for the environmental effects of outgassing of these lavas remains to be resolved. A substantial excursion in the marine carbon-isotope record of both carbonate and organic matter suggests a significant disturbance of the global carbon cycle at the system boundary. Release of methane hydrates from seafloor sediments is a possible cause for this isotope excursion, although the triggering mechanism and climatic effects of such a release remain uncertain. ?? 2003 Elsevier B.V. All rights reserved.

  9. Tradition and Technology: Sea Ice Science on Inuit Sleds

    NASA Astrophysics Data System (ADS)

    Wilkinson, Jeremy P.; Hanson, Susanne; Hughes, Nick E.; James, Alistair; Jones, Bryn; MacKinnon, Rory; Rysgaard, Søren; Toudal, Leif

    2011-01-01

    The Arctic is home to a circumpolar community of native people whose culture and traditions have enabled them to thrive in what most would perceive as a totally inhospitable and untenable environment. In many ways, sea ice can be viewed as the glue that binds these northern communities together; it is utilized in all aspects of their daily life. Sea ice acts as highways of the north; indeed, one can travel on these highways with dogsleds and snowmobiles. These travels over the frozen ocean occur at all periods of the sea ice cycle and over different ice types and ages. Excursions may be hunting trips to remote regions or social visits to nearby villages. Furthermore, hunting on the sea ice contributes to the health, culture, and commercial income of a community.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gottwald, M.; Kan, J. J.; Lee, K.

    Thermal budget, stack thickness, and dipolar offset field control are crucial for seamless integration of perpendicular magnetic junctions (pMTJ) into semiconductor integrated circuits to build scalable spin-transfer-torque magnetoresistive random access memory. This paper is concerned with materials and process tuning to deliver thermally robust (400 °C, 30 min) and thin (i.e., fewer layers and integration-friendly) pMTJ utilizing Co/Pt-based bottom pinned layers. Interlayer roughness control is identified as a key enabler to achieve high thermal budgets. The dipolar offset fields of the developed film stacks at scaled dimensions are evaluated by micromagnetic simulations. This paper shows a path towards achieving sub-15 nm-thick pMTJ withmore » tunneling magnetoresistance ratio higher than 150% after 30 min of thermal excursion at 400 °C.« less

  11. Non-Gaussianity and Excursion Set Theory: Halo Bias

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adshead, Peter; Baxter, Eric J.; Dodelson, Scott

    2012-09-01

    We study the impact of primordial non-Gaussianity generated during inflation on the bias of halos using excursion set theory. We recapture the familiar result that the bias scales asmore » $$k^{-2}$$ on large scales for local type non-Gaussianity but explicitly identify the approximations that go into this conclusion and the corrections to it. We solve the more complicated problem of non-spherical halos, for which the collapse threshold is scale dependent.« less

  12. Calcium isotope constraints on the end-Permian mass extinction

    PubMed Central

    Payne, Jonathan L.; Turchyn, Alexandra V.; Paytan, Adina; DePaolo, Donald J.; Lehrmann, Daniel J.; Yu, Meiyi; Wei, Jiayong

    2010-01-01

    The end-Permian mass extinction horizon is marked by an abrupt shift in style of carbonate sedimentation and a negative excursion in the carbon isotope (δ13C) composition of carbonate minerals. Several extinction scenarios consistent with these observations have been put forward. Secular variation in the calcium isotope (δ44/40Ca) composition of marine sediments provides a tool for distinguishing among these possibilities and thereby constraining the causes of mass extinction. Here we report δ44/40Ca across the Permian-Triassic boundary from marine limestone in south China. The δ44/40Ca exhibits a transient negative excursion of ∼0.3‰ over a few hundred thousand years or less, which we interpret to reflect a change in the global δ44/40Ca composition of seawater. CO2-driven ocean acidification best explains the coincidence of the δ44/40Ca excursion with negative excursions in the δ13C of carbonates and organic matter and the preferential extinction of heavily calcified marine animals. Calcium isotope constraints on carbon cycle calculations suggest that the average δ13C of CO2 released was heavier than -28‰ and more likely near -15‰; these values indicate a source containing substantial amounts of mantle- or carbonate-derived carbon. Collectively, the results point toward Siberian Trap volcanism as the trigger of mass extinction. PMID:20421502

  13. Comparison of Dynamic Balance in Collegiate Field Hockey and Football Players Using Star Excursion Balance Test

    PubMed Central

    Bhat, Rashi; Moiz, Jamal Ali

    2013-01-01

    Purpose The preliminary study aimed to compare dynamic balance between collegiate athletes competing or training in football and hockey using star excursion balance test. Methods A total thirty university level players, football (n = 15) and field hockey (n = 15) were participated in the study. Dynamic balance was assessed by using star excursion balance test. The testing grid consists of 8 lines each 120 cm in length extending from a common point at 45° increments. The subjects were instructed to maintain a stable single leg stance with the test leg with shoes off and to reach for maximal distance with the other leg in each of the 8 directions. A pencil was used to point and read the distance to which each subject's foot reached. The normalized leg reach distances in each direction were summed for both limbs and the total sum of the mean of summed normalized distances of both limbs were calculated. Results There was no significant difference in all the directions of star excursion balance test scores in both the groups. Additionally, composite reach distances of both groups also found non-significant (P=0.5). However, the posterior (P=0.05) and lateral (P=0.03) normalized reach distances were significantly more in field hockey players. Conclusion Field hockey players and football players did not differ in terms of dynamic balance. PMID:24427482

  14. Comparison of dynamic balance in collegiate field hockey and football players using star excursion balance test.

    PubMed

    Bhat, Rashi; Moiz, Jamal Ali

    2013-09-01

    The preliminary study aimed to compare dynamic balance between collegiate athletes competing or training in football and hockey using star excursion balance test. A total thirty university level players, football (n = 15) and field hockey (n = 15) were participated in the study. Dynamic balance was assessed by using star excursion balance test. The testing grid consists of 8 lines each 120 cm in length extending from a common point at 45° increments. The subjects were instructed to maintain a stable single leg stance with the test leg with shoes off and to reach for maximal distance with the other leg in each of the 8 directions. A pencil was used to point and read the distance to which each subject's foot reached. The normalized leg reach distances in each direction were summed for both limbs and the total sum of the mean of summed normalized distances of both limbs were calculated. There was no significant difference in all the directions of star excursion balance test scores in both the groups. Additionally, composite reach distances of both groups also found non-significant (P=0.5). However, the posterior (P=0.05) and lateral (P=0.03) normalized reach distances were significantly more in field hockey players. Field hockey players and football players did not differ in terms of dynamic balance.

  15. Doppler ultrasound surveillance in deep tunneling compressed-air work with Trimix breathing: bounce dive technique compared to saturation-excursion technique.

    PubMed

    Vellinga, T P van Rees; Sterk, W; de Boer, A G E M; van der Beek, A J; Verhoeven, A C; van Dijk, F J H

    2008-01-01

    The Western Scheldt Tunneling Project in The Netherlands provided a unique opportunity to evaluate two deep-diving techniques with Doppler ultrasound surveillance. Divers used the bounce diving techniques for repair and maintenance of the TBM. The tunnel boring machine jammed at its deepest depth. As a result the work time was not sufficient. The saturation diving technique was developed and permitted longer work time at great depth. Thirty-one divers were involved in this project. Twenty-three divers were examined using Doppler ultrasound. Data analysis addressed 52 exposures to Trimix at 4.6-4.8 bar gauge using the bounce technique and 354 exposures to Trimix at 4.0-6.9 bar gauge on saturation excursions. No decompression incidents occurred with either technique during the described phase of the project. Doppler ultrasound revealed that the bubble loads assessed in both techniques were generally low. We find out, that despite longer working hours, shorter decompression times and larger physical workloads, the saturation-excursion technique was associated with significant lower bubble grades than in the bounce technique using Doppler Ultrasound. We conclude that the saturation-excursion technique with Trimix is a good option for deep and long exposures in caisson work. The Doppler technique proved valuable, and it should be incorporated in future compressed-air work.

  16. Masticatory motion after surgical or nonsurgical treatment for unilateral fractures of the mandibular condylar process.

    PubMed

    Throckmorton, Gaylord S; Ellis, Edward; Hayasaki, Haruaki

    2004-02-01

    We sought to compare mandibular motion during mastication in patients treated in either an open or a closed fashion for unilateral fractures of the mandibular condylar process. Eighty-one male patients with unilateral condylar process fractures were treated either with (n = 37) or without (n = 44) surgical reduction and rigid fixation of their condylar process fractures. At 6 weeks, 6 months, 1 year, and 2 years after treatment, the subjects' chewing cycles were recorded using a magnetic sensor array (Sirognathograph; Siemens Corp, Bensheim, Germany) while chewing Gummi-Bears (HARIBO, Bonn, Germany) unilaterally on the same side as the fracture and on the opposite side. The chewing cycles were analyzed using a custom computer program, and the duration, excursive ranges, and 3-dimensional cycle shape were compared between the 2 treatment groups at each time interval using multilevel linear modeling statistics. The 2 treatment groups did not differ significantly for any measure of cycle duration or any excursive range (except lateral excursions at 1 year post-treatment) at any of the time intervals. However, the 3-dimensional cycle shapes of the 2 groups did differ significantly at all time intervals. Surgical correction of unilateral condylar process fractures has relatively little effect on the more standard measures (duration and excursive ranges) of masticatory function. However, surgical correction better normalizes opening incisor pathways during mastication on the side opposite the fracture.

  17. Accurate prediction of vaccine stability under real storage conditions and during temperature excursions.

    PubMed

    Clénet, Didier

    2018-04-01

    Due to their thermosensitivity, most vaccines must be kept refrigerated from production to use. To successfully carry out global immunization programs, ensuring the stability of vaccines is crucial. In this context, two important issues are critical, namely: (i) predicting vaccine stability and (ii) preventing product damage due to excessive temperature excursions outside of the recommended storage conditions (cold chain break). We applied a combination of advanced kinetics and statistical analyses on vaccine forced degradation data to accurately describe the loss of antigenicity for a multivalent freeze-dried inactivated virus vaccine containing three variants. The screening of large amounts of kinetic models combined with a statistical model selection approach resulted in the identification of two-step kinetic models. Predictions based on kinetic analysis and experimental stability data were in agreement, with approximately five percentage points difference from real values for long-term stability storage conditions, after excursions of temperature and during experimental shipments of freeze-dried products. Results showed that modeling a few months of forced degradation can be used to predict various time and temperature profiles endured by vaccines, i.e. long-term stability, short time excursions outside the labeled storage conditions or shipments at ambient temperature, with high accuracy. Pharmaceutical applications of the presented kinetics-based approach are discussed. Copyright © 2018 The Author. Published by Elsevier B.V. All rights reserved.

  18. Mammalian faunal response to the Early Eocene Climatic Optimum (~53.5-48.5 mya) and a new terrestrial record of the associated carbon isotope excursion from Raven Ridge in the Uinta Basin, Colorado-Utah

    NASA Astrophysics Data System (ADS)

    Dutchak, A. R.

    2010-12-01

    Raven Ridge straddles the Colorado-Utah border on the northeastern edge of the Uinta Basin and consists of intertonguing units of the fluvial Colton and lacustrine Green River Formations. Fossil vertebrate localities along the ridge have produced a diverse mammalian fauna comprising 64 genera in 34 families. Included are the index taxa Smilodectes, Omomys, Heptodon, and Lambdotherium which suggest an age range of mid-Wasatchian (Wa5, ~53.5mya) through mid Bridgerian (Br2, ~48.5mya) for the Raven Ridge fauna. Others have shown that this time interval coincides with the onset, peak, and decline of the Early Eocene Climatic Optimum (EECO), an extended interval of globally warm temperatures following the Paleocene-Eocene Thermal Maximum (PETM) that is coincident with a large negative carbon excursion. The Raven Ridge fauna provides an excellent opportunity to investigate the effects of a lengthy interval of global warmth on mammalian diversity and ecosystem structure. To study changes in the mammalian fauna that occurred during the EECO, it was necessary to constrain the onset, peak, and decline of the EECO at Raven Ridge through chemostratigraphic correlation with established marine isotope curves. This was accomplished by analysis of approximately 300 sediment samples for Total Organic Carbon (TOC) content. TOC has been used successfully in the Bighorn Basin to identify the stratigraphic occurrence of the Carbon Isotope Excursion (CIE) associated with the PETM, which has roughly the same amplitude as the negative excursion associated with the EECO. The Raven Ridge TOC data show a large negative carbon excursion that starts during the Wa6 biochron, peaks during the Wa7 biochron, and is followed by a positive excursion near the Wa-Br boundary. This terrestrial δ13C pattern is consistent with results seen in established marine isotope curves across the EECO interval. The minimum δ13C value of the negative excursion is -29.67‰, which is comparable to the Bighorn CIE values, and the maximum δ13C value of the positive excursion is -20.51‰. The Raven Ridge mammalian fauna shows a gradual increase in generic diversity from Wa5, when the fauna was dominated by terrestrially-adapted ischyromyid rodents and the condylarth Hyopsodus, through the Wa6 and Wa7 biochrons when arboreal primates including microsyopids, omomyids, and adapids, increased in diversity and relative abundance. These results are consistent with diversity trends seen in meta-analyses of North American mammalian diversity during the EECO. The diversity increase at Raven Ridge is mirrored by a change in ranked familial abundance from a skewed distribution during Wa5 to more even distributions during Wa6-Br1 time, an interval which is shown by previous studies in Wyoming to coincide with a significant increase in floral diversity. One interpretation of these patterns is that there was a floral shift associated with the EECO in central North America, with the relatively open habitats of the mid-Wasatchian being replaced by more densely forested canopy systems, with increased niche space allowing for diversification and increased abundance of arboreal taxa, during the late Wasatchian and early Bridgerian.

  19. RELIABILITY OF ANKLE-FOOT MORPHOLOGY, MOBILITY, STRENGTH, AND MOTOR PERFORMANCE MEASURES.

    PubMed

    Fraser, John J; Koldenhoven, Rachel M; Saliba, Susan A; Hertel, Jay

    2017-12-01

    Assessment of foot posture, morphology, intersegmental mobility, strength and motor control of the ankle-foot complex are commonly used clinically, but measurement properties of many assessments are unclear. To determine test-retest and inter-rater reliability, standard error of measurement, and minimal detectable change of morphology, joint excursion and play, strength, and motor control of the ankle-foot complex. Reliability study. 24 healthy, recreationally-active young adults without history of ankle-foot injury were assessed by two clinicians on two occasions, three to ten days apart. Measurement properties were assessed for foot morphology (foot posture index, total and truncated length, width, arch height), joint excursion (weight-bearing dorsiflexion, rearfoot and hallux goniometry, forefoot inclinometry, 1 st metatarsal displacement) and joint play, strength (handheld dynamometry), and motor control rating during intrinsic foot muscle (IFM) exercises. Clinician order was randomized using a Latin Square. The clinicians performed independent examinations and did not confer on the findings for the duration of the study. Test-retest and inter-tester reliability and agreement was assessed using intraclass correlation coefficients (ICC 2,k ) and weighted kappa ( K w ). Test-retest reliability ICC were as follows: morphology: .80-1.00, joint excursion: .58-.97, joint play: -.67-.84, strength: .67-.92, IFM motor rating: K W -.01-.71. Inter-rater reliability ICC were as follows: morphology: .81-1.00, joint excursion: .32-.97, joint play: -1.06-1.00, strength: .53-.90, and IFM motor rating: K w .02-.56. Measures of ankle-foot posture, morphology, joint excursion, and strength demonstrated fair to excellent test-retest and inter-rater reliability. Test-retest reliability for rating of perceived difficulty and motor performance was good to excellent for short-foot, toe-spread-out, and hallux exercises and poor to fair for lesser toe extension. Joint play measures had poor to fair reliability overall. The findings of this study should be considered when choosing methods of clinical assessment and outcome measures in practice and research. 3.

  20. Ocean sunfish rewarm at the surface after deep excursions to forage for siphonophores.

    PubMed

    Nakamura, Itsumi; Goto, Yusuke; Sato, Katsufumi

    2015-05-01

    Ocean sunfish (Mola mola) were believed to be inactive jellyfish feeders because they are often observed lying motionless at the sea surface. Recent tracking studies revealed that they are actually deep divers, but there has been no evidence of foraging in deep water. Furthermore, the surfacing behaviour of ocean sunfish was thought to be related to behavioural thermoregulation, but there was no record of sunfish body temperature. Evidence of ocean sunfish feeding in deep water was obtained using a combination of an animal-borne accelerometer and camera with a light source. Siphonophores were the most abundant prey items captured by ocean sunfish and were typically located at a depth of 50-200 m where the water temperature was <12 °C. Ocean sunfish were diurnally active, made frequently deep excursions and foraged mainly at 100-200 m depths during the day. Ocean sunfish body temperatures were measured under natural conditions. The body temperatures decreased during deep excursions and recovered during subsequent surfacing periods. Heat-budget models indicated that the whole-body heat-transfer coefficient between sunfish and the surrounding water during warming was 3-7 times greater than that during cooling. These results suggest that the main function of surfacing is the recovery of body temperature, and the fish might be able to increase heat gain from the warm surface water by physiological regulation. The thermal environment of ocean sunfish foraging depths was lower than their thermal preference (c. 16-17 °C). The behavioural and physiological thermoregulation enables the fish to increase foraging time in deep, cold water. Feeding rate during deep excursions was not related to duration or depth of the deep excursions. Cycles of deep foraging and surface warming were explained by a foraging strategy, to maximize foraging time with maintaining body temperature by vertical temperature environment. © 2015 The Authors. Journal of Animal Ecology © 2015 British Ecological Society.

  1. Coupled high-resolution marine and terrestrial records of carbon and hydrologic cycles variations during the Paleocene-Eocene Thermal Maximum (PETM)

    NASA Astrophysics Data System (ADS)

    Tipple, Brett J.; Pagani, Mark; Krishnan, Srinath; Dirghangi, Sitindra S.; Galeotti, Simone; Agnini, Claudia; Giusberti, Luca; Rio, Domenico

    2011-11-01

    The Paleocene-Eocene Thermal Maximum is characterized by a massive perturbation of the global carbon cycle reflected in a large, negative carbon isotope excursion associated with rapid global warming and changes in the hydrologic system. The magnitude of the carbon isotope excursion from terrestrial carbonates and organic carbon is generally larger relative to marine carbonates. However, high-resolution marine and terrestrial isotopic records from the same locality for direct comparison are limited. Here we present coupled carbon isotope records from terrestrial biomarkers (δ 13C n-alkane ), marine bulk carbonates (δ 13C carbonate), and bulk organic carbon (δ 13C organic) from the continuous sedimentary record of the Forada section in northern Italy in order to evaluate the magnitude and phase relationships between terrestrial and marine environments. Consistent with previous reports, we find that the carbon isotope excursion established from δ 13C n-alkane values is more negative than those established from δ 13C carbonate and δ 13C organic values. In contrast to the majority of PETM records, all Forada δ 13C records show a sharp 13C-enrichment immediately following the onset of the carbon isotope excursion. Further, the terrestrial δ 13C n-alkane record lags δ 13C carbonate/δ 13C organic trends by ~ 4-5 kyr—offsets that reflect the long residence time of soil organic carbon. Hydrogen isotope records from higher-plant leaf waxes (δD n-alkane ) and sea-surface temperatures (TEX 86) were established to assess hydrologic and ocean temperature trends. We find δD n-alkane values trend more positive, associated with higher temperatures prior to the onset of the carbon isotope excursion, and conclude that regional changes in the hydrologic cycle likely occurred before the onset of the carbon isotope anomaly.

  2. Cerium anomaly across the mid-Tournaisian carbon isotope excursion (TICE)

    NASA Astrophysics Data System (ADS)

    Jiang, G.; Morales, D. C.; Maharjan, D. K.

    2015-12-01

    The Early Mississippian (ca. 359-345 Ma) represents one of the most important greenhouse-icehouse climate transitions in Earth history. Closely associated with this critical transition is a prominent positive carbon isotope excursion (δ13C ≥ +5‰) that has been documented from numerous stratigraphic successions across the globe. This δ13C excursion, informally referred to as the TICE (mid-Tournaisian carbon isotope excursion) event, has been interpreted as resulting from enhanced organic carbon burial, with anticipated outcomes including the lowering of atmospheric CO2 and global cooling, the growth of continental ice sheets and sea-level fall, and the increase of ocean oxygenation and ocean redox changes. The casual relationship between these events has been addressed from various perspectives but not yet clearly demonstrated. To document the potential redox change associated with the perturbation of the carbon cycle, we have analyzed rare earth elements (REE) and trace elements across the TICE in two sections across a shallow-to-deep water transect in the southern Great Basin (Utah and Nevada), USA. In both sections, the REE data show a significant positive cerium (Ce) anomaly (Ce/Ce* = Ce/(0.5La+0.5Pr)). Prior to the positive δ13C shift, most Ce/Ce* values are around 0.3 (between 0.2 and 0.4). Across the δ13C peak, Ce/Ce* values increase up to 0.87, followed by a decrease back to 0.2~0.3 after the δ13C excursion (Figure 1). The positive Ce anomaly is best interpreted as recording expansion of oxygen minimum zone and anoxia resulted from increased primary production. This is consistent with a significant increase of nitrogen isotopes (δ15N) across the δ13C peak. Integration of the carbon, nitrogen, and REE data demonstrates a responsive earth systems change linked to the perturbation of the Early Mississippian carbon cycle.

  3. Re-evaluating the isotopic divide between angiosperms and gymnosperms using n-alkane δ13C values

    NASA Astrophysics Data System (ADS)

    Bush, R. T.; McInerney, F. A.

    2009-12-01

    Angiosperm δ13C values are typically 1-3‰ more negative than those of co-occurring gymnosperms. This is known for both bulk leaf and compound-specific values from n-alkanes, which are stable, straight-chain hydrocarbons (C23-C35) found in the epicuticular leaf wax of vascular plants. For n-alkanes, there is a second distinction between the δ13C values of angiosperms and gymnosperms—δ13C values generally decrease with increasing chain-length in angiosperms, while in gymnosperms they increase. These two distinctions have been used to support the ‘plant community change hypothesis’ explaining the difference between the terrestrial and marine carbon isotope excursions during the Paleocene-Eocene Thermal Maximum (PETM.) Preserved n-alkanes from terrestrial paleosols in the Bighorn Basin, Wyoming reveal a negative carbon isotope excursion during the PETM of 4-5‰, which is 1-2‰ greater than the excursion recorded by marine carbonates. The local plant community, known from macrofossils as well as palynoflora, shifted from a deciduous, mixed angiosperm/gymnosperm flora to a suite of evergreen angiosperm species during the PETM. At the end of the PETM, the community returned to a mixed deciduous flora very similar to the original. This change in the plant community could thus magnify the terrestrial negative carbon isotope excursion to the degree necessary to explain its divergence from the marine record. However, the comparison between modern angiosperms and gymnosperms has been made mostly between broadleaf, deciduous angiosperms and evergreen, coniferous gymnosperms. New data analyzing deciduous, coniferous gymnosperms, including Metasequoia glyptostroboides and Taxodium distichum, suggests that the division previously ascribed to taxonomy may actually be based on leaf habit and physiology, specifically broadleaf, deciduous versus needle-leaf, evergreen plants. If differences in n-alkane δ13C values can be described not as angiosperms versus gymnosperms, but as deciduous versus evergreen plants, then a re-examination of the PETM terrestrial carbon isotope excursion and its causes may be necessary.

  4. Linkage between the Biosphere and Geomagnetic field: Knowns and Unknowns

    NASA Astrophysics Data System (ADS)

    Pan, Y.; Zhu, R.

    2017-12-01

    The geomagnetic field extends from Earth's interior into space, and protects our planets habitability by shielding the planet from solar winds and cosmic rays. Recently, single zircon paleomagnetic study provides evidence of the field to ages as old as 4.2 Ga. Many great questions remain, including whether the emergence of life on Earth was a consequence of the field's protection, how organisms utilize the field, and if field variations (polarity reversal, excursion and secular variation) impact the evolution of the biosphere. In the past decade, great efforts have been made to probe these very complex and great challenging questions through the inter-disciplinary subject of biogeomagnetism. Numerous birds, fish, sea turtles, bats and many other organisms utilize the geomagnetic field during orientation and long-distance navigation. We recently found that bats, the second most abundant order of mammals, can use the direction of magnetic field with a weak strength comparable to polarity transitions/excursions, which is indicative of advanced magnetoreception developed in bats co-evolving with the geomagnetic field since the Eocene. Magnetotactic bacteria swim along the geomagnetic field lines by synthesizing intracellular nano-sized and chain-arranged magnetic minerals (magnetosomes). Recent field surveys in China, Europe, America and Australia have shown that these microbes are ubiquitous in aqueous habitats. Both their biogeography distribution and magnetotactic swimming speed are field intensity dependent. On the other hand, it is increasingly accepted that the geomagnetic field influences life through several indirect pathways. For example, it has been discovered that solar wind erosion enhanced the atmospheric oxygen escape during periods of weak magnetic field and global mean ionospheric electron density profiles can be affected by geomagnetic field strength variation. In addition, depletion of the ozone layer during a weak magnetic field could result in strong solar irradiation, which is harmful to many organisms. Together, newly accumulated lines of evidence strongly indicate that the geomagnetic field and its variations have important impacts on life and its evolution. In this paper we will provide an overview of recent observations, progresses and perspectives in this subject.

  5. Human and Robotic Exploration Missions to Phobos Prior to Crewed Mars Surface Missions

    NASA Technical Reports Server (NTRS)

    Gernhardt, Michael L.; Chappell, Steven P.; Bekdash, Omar S.; Abercromby, Andrew F. J.; Crues, Edwin Z.; Li, Zu Qun; Bielski, Paul; Howe, A. Scott

    2016-01-01

    Phobos is a scientifically significant destination that would facilitate the development and operation of the human Mars transportation infrastructure, unmanned cargo delivery systems and other Mars surface systems. In addition to developing systems relevant to Mars surface missions, Phobos offers engineering, operational, and public engagement opportunities that could enhance subsequent Mars surface operations. These opportunities include the use of low latency teleoperations to control Mars surface assets associated with exploration science, human landing-site selection and infrastructure development, which may include in situ resource utilization (ISRU) to provide liquid oxygen for the Mars Ascent Vehicle (MAV). A human mission to Mars' moons would be preceded by a cargo pre-deploy of a surface habitat and a pressurized excursion vehicle (PEV) to Mars orbit. Once in Mars orbit, the habitat and PEV would spiral to Phobos using solar electric propulsion based systems, with the habitat descending to the surface and the PEV remaining in orbit. When a crewed mission is launched to Phobos, it would include the remaining systems to support the crew during the Earth-Mars transit and to reach Phobos after insertion in to Mars orbit. The crew would taxi from Mars orbit to Phobos to join with the predeployed systems in a spacecraft that is based on a MAV, dock with and transfer to the PEV in Phobos orbit, and descend in the PEV to the surface habitat. A static Phobos surface habitat was chosen as a baseline architecture, in combination with the PEV that was used to descend from orbit as the main exploration vehicle. The habitat would, however, have limited capability to relocate on the surface to shorten excursion distances required by the PEV during exploration and to provide rescue capability should the PEV become disabled. To supplement exploration capabilities of the PEV, the surface habitat would utilize deployable EVA support structures that allow astronauts to work from portable foot restraints or body restrain tethers in the vicinity of the habitat. Prototype structures were tested as part of NEEMO 20.

  6. Testing and checkout experiences in the National Transonic Facility since becoming operational

    NASA Technical Reports Server (NTRS)

    Bruce, W. E., Jr.; Gloss, B. B.; Mckinney, L. W.

    1988-01-01

    The U.S. National Transonic Facility, constructed by NASA to meet the national needs for High Reynolds Number Testing, has been operational in a checkout and test mode since the operational readiness review (ORR) in late 1984. During this time, there have been problems centered around the effect of large temperature excursions on the mechanical movement of large components, the reliable performance of instrumentation systems, and an unexpected moisture problem with dry insulation. The more significant efforts since the ORR are reviewed and NTF status concerning hardware, instrumentation and process controls systems, operating constraints imposed by the cryogenic environment, and data quality and process controls is summarized.

  7. Optical Rogue Waves in Vortex Turbulence.

    PubMed

    Gibson, Christopher J; Yao, Alison M; Oppo, Gian-Luca

    2016-01-29

    We present a spatiotemporal mechanism for producing 2D optical rogue waves in the presence of a turbulent state with creation, interaction, and annihilation of optical vortices. Spatially periodic structures with bound phase lose stability to phase unbound turbulent states in complex Ginzburg-Landau and Swift-Hohenberg models with external driving. When the pumping is high and the external driving is low, synchronized oscillations are unstable and lead to spatiotemporal vortex-mediated turbulence with high excursions in amplitude. Nonlinear amplification leads to rogue waves close to turbulent optical vortices, where the amplitude tends to zero, and to probability density functions (PDFs) with long tails typical of extreme optical events.

  8. In situ SEM thermal fatigue of Al/graphite metal matrix composites

    NASA Technical Reports Server (NTRS)

    Zong, G. S.; Rabenberg, L.; Marcus, H. L.

    1990-01-01

    Several thermal fatigue-induced failure mechanisms are deduced for unidirectional graphite-reinforced 6061 Al-alloy MMCs subjected to in situ thermal cycling. These thermal cycling conditions are representative of MMC service cycles in aerospace environments, where thermal fatigue is primarily associated with changes in the stress states near the interfaces due to coefficient of thermal expansion mismatch between fiber and matrix. This in situ SEM thermal-cycling study clarified such factors affecting MMCs' thermal fatigue as local fiber content and distribution, void volume, fiber stiffness, thermal excursion magnitude, and number of thermal cycles. MMC microfailure modes in thermal fatigue have been deduced.

  9. Free-Piston Stirling Machine for Extreme Temperatures

    NASA Technical Reports Server (NTRS)

    Wood, James Gary (Inventor)

    2013-01-01

    A free piston Stirling machine including a thermal buffer tube extending from the machine's expansion space and surrounded by its heat rejector and its regenerator, a displacer cylinder extending from the thermal buffer tube to the compression space and surrounded by the heat rejecting heat exchanger, and a displacer that reciprocates within an excursion limit that extends into the regenerator by no more than 20% of the length of the regenerator during normal operation and preferably within excursion limits that are substantially the length of the heat rejector.

  10. Solar maximum mission panel jettison analysis remote manipulator system

    NASA Technical Reports Server (NTRS)

    Bauer, R. B.

    1980-01-01

    A study is presented of the development of the Remote Manipulator System (RMS) configurations for jettison of the solar panels on the Solar Maximum Mission/Multimission Satellite. A valid RMS maneuver between jettison configurations was developed. Arm and longeron loads and effector excursions due to the solar panel jettison were determined to see if they were within acceptable limits. These loads and end effector excursions were analyzed under two RMS modes, servos active in position hold submode, and in the brakes on mode.

  11. Estimates of the effectiveness of automatic control in alleviating wake vortex induced roll excursions

    NASA Technical Reports Server (NTRS)

    Tinling, B. E.

    1977-01-01

    Estimates of the effectiveness of a model following type control system in reducing the roll excursion due to a wake vortex encounter were obtained from single degree of freedom computations with inputs derived from the results of wind tunnel, flight, and simulation experiments. The analysis indicates that the control power commanded by the automatic system must be roughly equal to the vortex induced roll acceleration if effective limiting of the maximum bank angle is to be achieved.

  12. Limits of Wave Runup and Corresponding Beach-Profile Change from Large-Scale Laboratory Data

    DTIC Science & Technology

    2010-01-01

    A nearly vertical scarp developed after 40 min of wave action, with the upper limit of beach change identified at the toe of the dune scarp. and...change UL was found to approximately equal the vertical excursion of total wave runup, Rtw. An exception was runs where beach or dune scarps were...approximately equal the vertical excursion of total wave runup, Rtw. An exception was runs where beach or dune scarps were produced, which substantially limit the

  13. Excursion set mass functions for hierarchical Gaussian fluctuations

    NASA Technical Reports Server (NTRS)

    Bond, J. R.; Kaiser, N.; Cole, S.; Efstathiou, G.

    1991-01-01

    It is pointed out that most schemes for determining the mass function of virialized objects from the statistics of the initial density perturbation field suffer from the cloud-in-cloud problem of miscounting the number of low-mass clumps, many of which would have been subsumed into larger objects. The paper proposes a solution based on the theory of the excursion sets of F(r, R sub f), the four-dimensional initial density perturbation field smoothed with a continuous hierarchy of filters of radii R sub f.

  14. Lateral ligament repair and reconstruction restore neither contact mechanics of the ankle joint nor motion patterns of the hindfoot.

    PubMed

    Prisk, Victor R; Imhauser, Carl W; O'Loughlin, Padhraig F; Kennedy, John G

    2010-10-20

    Ankle sprains may damage both the lateral ligaments of the hindfoot and the osteochondral tissue of the ankle joint. When nonoperative treatment fails, operative approaches are indicated to restore both native motion patterns at the hindfoot and ankle joint contact mechanics. The goal of the present study was to determine the effect of lateral ligament injury, repair, and reconstruction on ankle joint contact mechanics and hindfoot motion patterns. Eight cadaveric specimens were tested with use of robotic technology to apply combined compressive (200-N) and inversion (4.5-Nm) loads to the hindfoot at 0° and 20° of plantar flexion. Contact mechanics at the ankle joint were simultaneously measured. A repeated-measures experiment was designed with use of the intact condition as control, with the other conditions including sectioned anterior talofibular and calcaneofibular ligaments, the Broström and Broström-Gould repairs, and graft reconstruction. Ligament sectioning decreased contact area and caused a medial and anterior shift in the center of pressure with inversion loads relative to those with the intact condition. There were no significant differences in inversion or coupled axial rotation with inversion between the Broström repair and the intact condition; however, medial translation of the center of pressure remained elevated after the Broström repair relative to the intact condition. The Gould modification of the Broström procedure provided additional support to the hindfoot relative to the Broström repair, reducing inversion and axial rotation with inversion beyond that of intact ligaments. There were no significant differences in center-of-pressure excursion patterns between the Broström-Gould repair and the intact ligament condition, but this repair increased contact area beyond that with the ligaments intact. Graft reconstruction more closely restored inversion motion than did the Broström-Gould repair at 20° of plantar flexion but limited coupled axial rotation. Graft reconstruction also increased contact areas beyond the lateral ligament-deficient conditions but altered center-of-pressure excursion patterns relative to the intact condition. No lateral ankle ligament reconstruction completely restored native contact mechanics of the ankle joint and hindfoot motion patterns.

  15. Osmium isotope perturbations during the Pliensbachian-Toarcian (Early Jurassic): Relationships between volcanism, weathering, and climate change

    NASA Astrophysics Data System (ADS)

    Percival, Lawrence; Cohen, Anthony; Davies, Marc; Dickson, Alexander; Jenkyns, Hugh; Hesselbo, Stephen; Mather, Tamsin; Xu, Weimu; Storm, Marisa

    2016-04-01

    The Mesozoic Era marked a time of greenhouse conditions on Earth, punctuated by a number of abrupt perturbations to the carbon cycle, such as Ocean Anoxic Events (OAEs). OAEs are typically marked in the stratigraphic record by the appearance of organic-rich shales, and excursions in carbon-isotope ratios registered in carbonates and organic matter. A range of geochemical evidence indicates changes to global temperatures, typically featuring abrupt warming possibly caused by CO2 emissions resulting from Large Igneous Province (LIP) volcanism. A warmer atmosphere is thought to have led to changes in the global hydrological cycle, which would likely have enhanced global weathering rates. The Toarcian OAE (T-OAE) is inferred, from osmium isotope ratios in organic-rich mudrocks from Yorkshire and western North America, to have been a time of such increased weathering rates. However, it is likely that the sediments at these locations were deposited in relatively hydrographically restricted environments, potentially more susceptible to the influence of local input; consequently, they may not offer the best representation of the global seawater Os-isotope composition at that time. In this study, we have measured the osmium isotope composition of siciliclastic mudrocks in a core from the Mochras borehole (Llanbedr Farm, Cardigan Bay Basin, Wales), which constitutes a sedimentary record for a fully open-marine seaway that connected Tethys to the Boreal ocean during the Toarcian. We analysed samples from strata including both the T-OAE and preceding Pliensbachian-Toarcian boundary (Pl-To), both of which record multiple geochemical excursions and records of elevated extinction amongst benthic fauna. We find that the latest Pliensbachian records seawater 187Os/188Os of ~0.35-0.4, rising to ~0.5 at the Pl-To boundary, before a further rise to ~0.7 during the T-OAE. We conclude that such increases in radiogenic Os flux to the ocean system resulted from enhanced continental weathering, and note that both excursions coincide with negative excursions in δ13C (indicating a massive release of isotopically light carbon to the atmosphere) and positive excursions in Hg/TOC (indicating enhanced volcanic activity associated with the Karoo-Ferrar LIP). These concurrent changes suggest that carbon-emissions related to the Karoo-Ferrar may have aided climate warming, leading to the enhanced weathering and marine anoxia recorded in Toarcian strata. Additionally, we record a potential lag in the recovery of 187Os/188Os compared to δ13C; such a lag would support previous hypotheses that enhanced weathering contributed towards draw-down of excess atmospheric carbon, alleviating the Toarcian warming. Finally, our recording of a second (stratigraphically lower) excursion in Os isotopes, coincident with previously recorded excursions, indicates that major climate change during the Toarcian in fact began, albeit to a lesser degree, at the Pl-To boundary, rather than being restricted solely to the T-OAE.

  16. Sulfur record of rising and falling marine oxygen and sulfate levels during the Lomagundi event

    PubMed Central

    Planavsky, Noah J.; Bekker, Andrey; Hofmann, Axel; Owens, Jeremy D.; Lyons, Timothy W.

    2012-01-01

    Carbonates from approximately 2.3–2.1 billion years ago show markedly positive δ13C values commonly reaching and sometimes exceeding +10‰. Traditional interpretation of these positive δ13C values favors greatly enhanced organic carbon burial on a global scale, although other researchers have invoked widespread methanogenesis within the sediments. To resolve between these competing models and, more generally, among the mechanisms behind Earth’s most dramatic carbon isotope event, we obtained coupled stable isotope data for carbonate carbon and carbonate-associated sulfate (CAS). CAS from the Lomagundi interval shows a narrow range of δ34S values and concentrations much like those of Phanerozoic and modern marine carbonate rocks. The δ34S values are a close match to those of coeval sulfate evaporites and likely reflect seawater composition. These observations are inconsistent with the idea of diagenetic carbonate formation in the methanic zone. Toward the end of the carbon isotope excursion there is an increase in the δ34S values of CAS. We propose that these trends in C and S isotope values track the isotopic evolution of seawater sulfate and reflect an increase in pyrite burial and a crash in the marine sulfate reservoir during ocean deoxygenation in the waning stages of the positive carbon isotope excursion. PMID:23090989

  17. Osmium isotope evidence for a large Late Triassic impact event

    PubMed Central

    Sato, Honami; Onoue, Tetsuji; Nozaki, Tatsuo; Suzuki, Katsuhiko

    2013-01-01

    Anomalously high platinum group element concentrations have previously been reported for Upper Triassic deep-sea sediments, which are interpreted to be derived from an extraterrestrial impact event. Here we report the osmium (Os) isotope fingerprint of an extraterrestrial impact from Upper Triassic chert successions in Japan. Os isotope data exhibit a marked negative excursion from an initial Os isotope ratio (187Os/188Osi) of ∼0.477 to unradiogenic values of ∼0.126 in a platinum group element-enriched claystone layer, indicating the input of meteorite-derived Os into the sediments. The timing of the Os isotope excursion coincides with both elevated Os concentrations and low Re/Os ratios. The magnitude of this negative Os isotope excursion is comparable to those found at Cretaceous–Paleogene boundary sites. These geochemical lines of evidence demonstrate that a large impactor (3.3–7.8 km in diameter) produced a global decrease in seawater 187Os/188Os ratios in the Late Triassic. PMID:24036603

  18. Magnetic flux ropes in the Venus ionosphere - Observations and models

    NASA Technical Reports Server (NTRS)

    Elphic, R. C.; Russell, C. T.

    1983-01-01

    Pioneer Venus Orbiter data are used as evidence of naturally occurring magnetic field filamentary structures which can be described by a flux rope model. The solar wind is interpreted as piling up a magnetic field on the Venus ionosphere, with the incident ram pressure being expressed as magnetic field pressure. Currents flowing at the ionopause shield out the field, allowing magnetic excursions to be observed with magnitudes of tens of nT over an interval of a few seconds. A quantitative assessment is made of the signature expected from a flux rope. It is noted that each excursion of the magnetic field detected by the Orbiter magnetometer was correlated with variations in the three components of the field. A coordinate system is devised which shows that the Venus data is indicative of the presence of flux ropes whose parameters are the coordinates of the system and would yield the excursions observed in the spacecraft crossings of the fields.

  19. Repeated Carbon-Cycle Disturbances at the Permian-Triassic Boundary Separate two Mass Extinctions

    NASA Astrophysics Data System (ADS)

    Nicol, J. A.; Watson, L.; Claire, M.; Buick, R.; Catling, D. C.

    2004-12-01

    Non-marine organic matter in Permian-Triassic sediments from the Blue Mountains, eastern Australia shows seven negative δ13C excursions of up to 7%, terminating with a positive excursion of 4%. Fluctuations start at the late Permian Glossopteris floral extinction and continue until just above the palynological Permian-Triassic boundary, correlated with the peak of marine mass extinction. The isotopic fluctuations are not linked to changes in depositional setting, kerogen composition or plant community, so they evidently resulted from global perturbations in atmospheric δ13C and/or CO2. The pattern was not produced by a single catastrophe such as a meteorite impact, and carbon-cycle calculations indicate that gas release during flood-basalt volcanism was insufficient. Methane-hydrate melting can generate a single -7% shift, but cannot produce rapid multiple excursions without repeated reservoir regeneration and release. However, the data are consistent with repeated overturning of a stratified ocean, expelling toxic gases that promoted sequential mass extinctions in the terrestrial and marine realms.

  20. Stable and 'bounded excursion' gravastars, and black holes in Einstein's theory of gravity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rocha, P; Da Silva, M F A; Wang, Anzhong

    2008-11-15

    Dynamical models of prototype gravastars are constructed and studied. The models are the Visser-Wiltshire three-layer gravastars, in which an infinitely thin spherical shell of a perfect fluid with the equation of state p = (1-{gamma}){sigma} divides the whole spacetime into two regions, where the internal region is de Sitter, and the external one is Schwarzschild. When {gamma}<1 and {Lambda}{ne}0, it is found that in some cases the models represent stable gravastars, and in some cases they represent 'bounded excursion' stable gravastars, where the thin shell is oscillating between two finite radii, while in some other cases they collapse until themore » formation of black holes occurs. However, when {gamma}{>=}1, even with {Lambda}{ne}0, only black holes are found. In the phase space, the region for both stable gravastars and 'bounded excursion' gravastars is very small in comparison to that for black holes, although it is not completely empty.« less

  1. Mechanical Balance Laws for Boussinesq Models of Surface Water Waves

    NASA Astrophysics Data System (ADS)

    Ali, Alfatih; Kalisch, Henrik

    2012-06-01

    Depth-integrated long-wave models, such as the shallow-water and Boussinesq equations, are standard fare in the study of small amplitude surface waves in shallow water. While the shallow-water theory features conservation of mass, momentum and energy for smooth solutions, mechanical balance equations are not widely used in Boussinesq scaling, and it appears that the expressions for many of these quantities are not known. This work presents a systematic derivation of mass, momentum and energy densities and fluxes associated with a general family of Boussinesq systems. The derivation is based on a reconstruction of the velocity field and the pressure in the fluid column below the free surface, and the derivation of differential balance equations which are of the same asymptotic validity as the evolution equations. It is shown that all these mechanical quantities can be expressed in terms of the principal dependent variables of the Boussinesq system: the surface excursion η and the horizontal velocity w at a given level in the fluid.

  2. Compound-specific carbon isotopes from Earth’s largest flood basalt eruptions directly linked to the end-Triassic mass extinction

    PubMed Central

    Whiteside, Jessica H.; Olsen, Paul E.; Eglinton, Timothy; Brookfield, Michael E.; Sambrotto, Raymond N.

    2010-01-01

    A leading hypothesis explaining Phanerozoic mass extinctions and associated carbon isotopic anomalies is the emission of greenhouse, other gases, and aerosols caused by eruptions of continental flood basalt provinces. However, the necessary serial relationship between these eruptions, isotopic excursions, and extinctions has never been tested in geological sections preserving all three records. The end-Triassic extinction (ETE) at 201.4 Ma is among the largest of these extinctions and is tied to a large negative carbon isotope excursion, reflecting perturbations of the carbon cycle including a transient increase in CO2. The cause of the ETE has been inferred to be the eruption of the giant Central Atlantic magmatic province (CAMP). Here, we show that carbon isotopes of leaf wax derived lipids (n-alkanes), wood, and total organic carbon from two orbitally paced lacustrine sections interbedded with the CAMP in eastern North America show similar excursions to those seen in the mostly marine St. Audrie’s Bay section in England. Based on these results, the ETE began synchronously in marine and terrestrial environments slightly before the oldest basalts in eastern North America but simultaneous with the eruption of the oldest flows in Morocco, a CO2 super greenhouse, and marine biocalcification crisis. Because the temporal relationship between CAMP eruptions, mass extinction, and the carbon isotopic excursions are shown in the same place, this is the strongest case for a volcanic cause of a mass extinction to date. PMID:20308590

  3. Uranium isotope evidence for the abrupt onset of oceanic anoxia during the end-Guadalupian mass extinction

    NASA Astrophysics Data System (ADS)

    Song, H.; Algeo, T. J.; Romaniello, S. J.; Tong, J.; Du, Y.; Wei, H.; Shen, S.; Anbar, A. D.

    2016-12-01

    The end-Guadalupian (Middle/Late Permian) mass extinction was one of the major crises of the Phanerozoic, resulting in the disappearance of numerous shallow-marine taxa. Several hypotheses have been proposed for this catastrophe but are still under debate. Here, we undertook a high-resolution carbonate U isotopic (δ238/235U) study of the Guadalupian-Lopingian boundary (GLB) at the Penglaitan section (Guadalupian/ Lopingian GSSP) to explore the causal relationship between ocean redox changes and the mass extinction event. The Penglaitan δ238U profile shows two abrupt negative excursions, one in the uppermost Guadalupian (Beds 6j-6k) and the other in the lowermost Lopingian (lower Bed 7). The first excursion (from ‒0.30 ‰ to ‒0.50 ‰) coincided with the main extinction event, suggesting that rapid expansion of oceanic anoxia may have been a contributor to the biotic crisis. The second, larger excursion (from ‒0.25 ‰ to ‒0.65 ‰) demonstrates that the crisis interval was marked by multiple phases of expanded oceanic anoxia. A U-isotope mass balance model shows that, during these excursions, the anoxic/euxinic sink flux increased to 40 % of the total sink flux of seawater U, which is three times of the modern ocean value of 13 %. This study thus provides circumstantial evidence for a causal relationship between expansion of oceanic anoxia and the end-Guadalupian biotic crisis.

  4. Comparison of excursive occlusal force parameters in post-orthodontic and non-orthodontic subjects using T-Scan® III.

    PubMed

    Qadeer, Sarah; Abbas, Ahmed A; Sarinnaphakorn, Lertrit; Kerstein, Robert B

    2018-01-01

    Published studies indicate that orthodontically treated patients demonstrate increased posterior occlusal friction contributing to temporomandibular disorder (TMD) symptoms. This study investigated measured excursive movement occlusal contact parameters and their association with TMD symptoms between non- and post-orthodontic subjects. Twenty-five post-orthodontic and 25 non-orthodontic subjects underwent T-Scan® computerized occlusal analysis to determine their disclusion time (DT), the excursive frictional contacts, and occlusal scheme. Each subject answered a TMD questionnaire to determine the presence or absence of TMD symptoms. Statistical analysis compared the within group and between group differences (p < 0.05). Statistically significant differences were observed in the disclusion time: DT = 2.69 s in the post-orthodontic and 1.36 s in the non-orthodontic group. In the non-orthodontic group, 72.7% working and 27.3% non-working side contacts were seen, while in the post-orthodontic group, (near equal) 54.7% working and 45.3% non-working side contacts were seen. Presence of canine guidance was seen in 60% of the non-orthodontic group and 24% in the post-orthodontic group. Seventy-two percent of the post orthodontics subjects presented with one or more TMD symptoms. Significantly longer disclusion time, higher posterior frictional contacts, and more TMD symptoms were observed in the post-orthodontic group, suggesting that orthodontic treatment increases posterior tooth friction. Computerized occlusal analysis is an objective diagnostic tool determining the quality of excursive movements following orthodontic treatment.

  5. Effect of a new hypoglycemic agent, A-4166 [(-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine], on postprandial blood glucose excursion: comparison with voglibose and glibenclamide.

    PubMed

    Ikenoue, T; Okazaki, K; Fujitani, S; Tsuchiya, Y; Akiyoshi, M; Maki, T; Kondo, N

    1997-04-01

    (-)-N-(trans-4-Isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166) is a new nonsulfonylurea hypoglycemic agent that lowers blood glucose by stimulating insulin release. In the present study, we examined the effects of A-4166, voglibose (an alpha-glucosidase inhibitor), and glibenclamide (a sulfonylurea) on the postprandial glycemic increase in rats with or without diabetes mellitus. Oral administration of A-4166 (25-100 mg/kg) dose-dependently decreased blood glucose with a rapid onset and short duration in normal rats. On the other hand, glibenclamide (1-4 mg/kg) showed a slower onset of its hypoglycemic action, and voglibose (0.2 mg/kg) had no effect. In the case of postprandial glucose excursion, the carbohydrate-induced increase in blood glucose was reduced by oral administration of either A-4166 or voglibose without causing sustained hypoglycemia in both normal and neonatal streptozotocin-induced diabetic rats. However, the efficacy of voglibose varied with the type of carbohydrate load. Glibenclamide produced a prolonged decrease in blood glucose without any appreciable effect on the initial glucose excursion. After sucrose loading, plasma insulin levels during the initial 1 h were significantly higher in A-4166-treated rats than in control rats, while voglibose completely inhibited the insulin response to sucrose. In glibenclamide-treated rats, an augmented insulin response was not seen. In conclusion, unlike other hypoglycemic agents, A-4166 suppresses postprandial glucose excursions by stimulating the early phase of insulin secretion.

  6. Diurnal forcing of planetary atmospheres

    NASA Technical Reports Server (NTRS)

    Houben, Howard C.

    1991-01-01

    The utility of the Mars Planetary Boundary Layer Model (MPBL) for calculations in support of the Mars 94 balloon mission was substantially enhanced by the introduction of a balloon equation of motion into the model. Both vertical and horizontal excursions of the balloon are calculated along with its volume, temperature, and pressure. The simulations reproduce the expected 5-min vertical oscillations of a constant density balloon at altitude on Mars. The results of these calculations are presented for the nominal target location of the balloon. A nonlinear balanced model was developed for the Martian atmosphere. It was used to initialize a primitive equation model for the simulations of the Earth's atmosphere at the time of the El Chichon eruption in 1982. It is also used as an assimilation model to update the temperature and wind fields at frequent intervals.

  7. Vaccine stability study design and analysis to support product licensure.

    PubMed

    Schofield, Timothy L

    2009-11-01

    Stability evaluation supporting vaccine licensure includes studies of bulk intermediates as well as final container product. Long-term and accelerated studies are performed to support shelf life and to determine release limits for the vaccine. Vaccine shelf life is best determined utilizing a formal statistical evaluation outlined in the ICH guidelines, while minimum release is calculated to help assure adequate potency through handling and storage of the vaccine. In addition to supporting release potency determination, accelerated stability studies may be used to support a strategy to recalculate product expiry after an unintended temperature excursion such as a cold storage unit failure or mishandling during transport. Appropriate statistical evaluation of vaccine stability data promotes strategic stability study design, in order to reduce the uncertainty associated with the determination of the degradation rate, and the associated risk to the customer.

  8. The humanation of Mars

    NASA Astrophysics Data System (ADS)

    David, L. W.

    Early developments related to human excursions to Mars are examined, taking into account plans considered by von Braun, and the 'ambitious goal of a manned flight to Mars by the end of the century', proposed at the launch of Apollo 11. In response to public reaction, plans for manned flights to Mars in the immediate future were given up, and unmanned reconnaissance of Mars was continued. An investigation is conducted concerning the advantages of manned exploration of Mars in comparison to a study by unmanned space probes, and arguments regarding a justification for interplanetary flight to Mars are discussed. Attention is given to the possibility to consider Mars as a 'back-up' planet for preserving earth life, an international Mars expedition as a world peace project, the role of Mars in connection with resource utilization considerations, and questions of exploration ethics.

  9. Accurate Predictions of Mean Geomagnetic Dipole Excursion and Reversal Frequencies, Mean Paleomagnetic Field Intensity, and the Radius of Earth's Core Using McLeod's Rule

    NASA Technical Reports Server (NTRS)

    Voorhies, Coerte V.; Conrad, Joy

    1996-01-01

    The geomagnetic spatial power spectrum R(sub n)(r) is the mean square magnetic induction represented by degree n spherical harmonic coefficients of the internal scalar potential averaged over the geocentric sphere of radius r. McLeod's Rule for the magnetic field generated by Earth's core geodynamo says that the expected core surface power spectrum (R(sub nc)(c)) is inversely proportional to (2n + 1) for 1 less than n less than or equal to N(sub E). McLeod's Rule is verified by locating Earth's core with main field models of Magsat data; the estimated core radius of 3485 kn is close to the seismologic value for c of 3480 km. McLeod's Rule and similar forms are then calibrated with the model values of R(sub n) for 3 less than or = n less than or = 12. Extrapolation to the degree 1 dipole predicts the expectation value of Earth's dipole moment to be about 5.89 x 10(exp 22) Am(exp 2)rms (74.5% of the 1980 value) and the expected geomagnetic intensity to be about 35.6 (mu)T rms at Earth's surface. Archeo- and paleomagnetic field intensity data show these and related predictions to be reasonably accurate. The probability distribution chi(exp 2) with 2n+1 degrees of freedom is assigned to (2n + 1)R(sub nc)/(R(sub nc). Extending this to the dipole implies that an exceptionally weak absolute dipole moment (less than or = 20% of the 1980 value) will exist during 2.5% of geologic time. The mean duration for such major geomagnetic dipole power excursions, one quarter of which feature durable axial dipole reversal, is estimated from the modern dipole power time-scale and the statistical model of excursions. The resulting mean excursion duration of 2767 years forces us to predict an average of 9.04 excursions per million years, 2.26 axial dipole reversals per million years, and a mean reversal duration of 5533 years. Paleomagnetic data show these predictions to be quite accurate. McLeod's Rule led to accurate predictions of Earth's core radius, mean paleomagnetic field intensity, and mean geomagnetic dipole power excursion and axial dipole reversal frequencies. We conclude that McLeod's Rule helps unify geo-paleomagnetism, correctly relates theoretically predictable statistical properties of the core geodynamo to magnetic observation, and provides a priori information required for stochastic inversion of paleo-, archeo-, and/or historical geomagnetic measurements.

  10. Middle-Upper Permian carbon isotope stratigraphy at Chaotian, South China: Pre-extinction multiple upwelling of oxygen-depleted water onto continental shelf

    NASA Astrophysics Data System (ADS)

    Saitoh, Masafumi; Isozaki, Yukio; Ueno, Yuichiro; Yoshida, Naohiro; Yao, Jianxin; Ji, Zhansheng

    2013-05-01

    In order to examine the causal relationships between the carbon cycle in a shallow euphotic zone and the environmental changes in a relatively deep disphotic zone at the end-Guadalupian (Middle Permian), isotopic compositions of carbonate carbon (δ13Ccarb) of the Guadalupian-Lopingian (Upper Permian) rocks were analyzed in the Chaotian section in northern Sichuan, South China. By analyzing exceptionally fresh drill core samples, a continuous chemostratigraphic record was newly obtained. The ca. 65 m-thick analyzed carbonate rocks at Chaotian comprise three stratigraphic units, i.e., the Limestone Unit of the Guadalupian Maokou Formation, the Mudstone Unit of the Maokou Formation, and the lower part of the Wuchiapingian (Lower Lopingian) Wujiaping Formation, in ascending order. The Limestone Unit of the Maokou Formation is characterized by almost constant δ13Ccarb values of ca. +4‰ followed by an abrupt drop for 7‰ to -3‰ in the topmost part of the unit. In the Mudstone Unit of the Maokou Formation, the δ13Ccarb values are rather constant around +2‰, although distinct three isotopic negative excursions for 3‰ from ca. +2 to -1‰ occurred in the upper part of the unit. In the lower part of the Wujiaping Formation, the δ13Ccarb values monotonously increase for 5‰ from ca. 0 to +5‰. The present data newly demonstrated four isotopic negative excursions in the topmost part of the Maokou Formation in the Capitanian (Late Guadalupian) at Chaotian. It is noteworthy that these negative excursions are in accordance with the emergence of an oxygen-depleted condition on the relatively deep disphotic slope/basin on the basis of litho- and bio-facies characteristics. They suggest multiple upwelling of oxygen-depleted waters with dissolved inorganic carbon of relatively low carbon isotope values along the continental margin, from the deeper disphotic slope/basin to the shallower euphotic shelf, slightly before the end-Guadalupian extinction. Although the negative excursions at Chaotian are apparently correlated with the previously proposed large negative excursion in the middle Capitanian in South China, the age difference according to the biostratigraphic constraints clearly exclude this interpretation. The isotopic negative excursions at Chaotian are unique and no similar isotopic signal in the same period has been reported elsewhere. The multiple upwelling of oxygen-depleted waters onto the euphotic shelf may have represented local phenomena that occurred solely around northwestern South China.

  11. Peccei-Quinn relaxion

    NASA Astrophysics Data System (ADS)

    Jeong, Kwang Sik; Shin, Chang Sub

    2018-01-01

    The relaxation mechanism, which solves the electroweak hierarchy problem without relying on TeV scale new physics, crucially depends on how a Higgs-dependent back-reaction potential is generated. In this paper, we suggest a new scenario in which the scalar potential induced by the QCD anomaly is responsible both for the relaxation mechanism and the Peccei-Quinn mechanism to solve the strong CP problem. The key idea is to introduce the relaxion and the QCD axion whose cosmic evolutions become quite different depending on an inflaton-dependent scalar potential. Our scheme raises the cutoff scale of the Higgs mass up to 107 GeV, and allows reheating temperature higher than the electroweak scale as would be required for viable cosmology. In addition, the QCD axion can account for the observed dark matter of the universe as produced by the conventional misalignment mechanism. We also consider the possibility that the couplings of the Standard Model depend on the inflaton and become stronger during inflation. In this case, the relaxation can be implemented with a sub-Planckian field excursion of the relaxion for a cutoff scale below 10 TeV.

  12. Protection of children in forward-facing child restraint systems during oblique side impact sled tests: Intrusion and tether effects.

    PubMed

    Hauschild, Hans W; Humm, John R; Pintar, Frank A; Yoganandan, Narayan; Kaufman, Bruce; Kim, Jinyong; Maltese, Matthew R; Arbogast, Kristy B

    2016-09-01

    Testing was conducted to quantify the kinematics, potential for head impact, and influence on head injury metrics for a center-seated Q3s in a forward-facing child restraint system (FFCRS) in oblique impacts. The influences of a tether and intruded door on these measures were explored. Nine lateral oblique sled tests were conducted on a convertible forward-facing child restraint seat (FFCRS). The FFCRSs were secured to a bench seat from a popular production small SUV at the center seating position utilizing the lower anchor and tether for children (LATCH). The vehicle seat was fixed on the sled carriage at 60° and 80° from full frontal (30° and 10° forward rotation from pure lateral) providing an oblique lateral acceleration to the Q3s and FFCRS. A structure simulating an intruded door was mounted to the near (left) side of vehicle seat. The sled input acceleration was the proposed FMVSS 213 lateral pulse scaled to a 35 km/h delta-V. Tests were conducted with and without the tether attached to the FFCRS. Results indicate the influence of the tether on kinematics and injury measures in oblique side impact crashes for a center- or far-side-seated child occupant. All tests without a tether resulted in head contact with the simulated door, and 2 tests at the less oblique angle (80°) with a tether also resulted in head contact. No head-to-door contact was observed in 2 tests utilizing a tether. High-speed video analysis showed that the head moved beyond the CRS head side wings and made contact with the simulated intruded door. Head injury criterion (HIC) 15 median values were 589 without the tether vs. 332 with the tether attached. Tests utilizing a tether had less lateral head excursion than tests without a tether (median 400 vs. 442 mm). These tests demonstrate the important role of the tether in controlling head excursion for center- or far-side-seated child occupants in oblique side impact crashes and limiting the head injury potential with an intruded door. The tether may not influence the kinematics of a near-side-seated occupant as strongly where the vehicle door or side structure interacts with the CRS and influences its motion. The results indicate that there may be an opportunity to improve child head kinematics and head protection in oblique side impacts through different CRS attachment methods and/or alternative vehicle side structure protection or padding.

  13. A comparative assessment of the role of anoxia during the Cambrian SPICE event

    NASA Astrophysics Data System (ADS)

    LeRoy, M.; Gill, B. C.; Sperling, E. A.

    2017-12-01

    The Cambrian SPICE (Steptoean Positive Carbon Isotope Excursion) is recognized as a major oceanographic event recorded in globally-distributed stratigraphic sections as positive isotopic excursions in marine carbonates (δ13Ccarb), organic matter (δ13Corg), sulfate (δ34SCAS) and pyrite (δ34Spy). A proposed mechanism for these observed isotopic trends is that a transient increase in the areal extent of anoxic conditions within the oceans fostered enhanced burial of organic carbon and pyrite. However, direct sedimentary (e.g., abundant black shale) and geochemical (e.g., redox proxy) evidence for such a shift is scant. While the antiquity of this event is likely responsible for loss of much of this evidence, through destruction by tectonic processes, a number of stratigraphic successions suitable for investigating this hypothesis exist. Here we explore the relationship between anoxia and the SPICE using previously published and novel data generated from core material from three sedimentary basins distributed along the margins of the Iapetus Ocean. The units studied are: the Nolichucky Formation of eastern Laurentia, the Alum Shale of Baltica, and the Outwoods Shale of Avalonia. Our iron speciation data indicate consistently oxic conditions prior to the SPICE along Laurentia, while Avalonia was oxic with intervals of anoxia, and Baltica was persistently anoxic. With the initiation of the SPICE, anoxic conditions intensified in Laurentia and Avalonia and continued to persist in Baltica. This redox shift was coupled with a sharp rise in δ34Spy at all three locations. Average total organic carbon (TOC) showed little change in relation to the SPICE at the Laurentia location ( 0.15 wt%), but showed an increase in conjunction with the excursion in both the Avalonia ( 1 to 1.5 wt%) and Baltica ( 8 to 12 wt%) sections. Large differences in nutrient availability and sedimentation rates are likely responsible for the between-site disparity in TOC, while overall, anoxia-intensified during the SPICE-enhanced organic preservation particularly in the Avalonia and Baltica locations. Our data presented here provide compelling geochemical evidence for increased anoxia and organic carbon burial associated with the SPICE while also illustrating important differences in its localized stratigraphic expression.

  14. Silurian carbonate high-energy deposits of potential tsunami origin: Distinguishing lateral redeposition and time averaging using carbon isotope chemostratigraphy

    NASA Astrophysics Data System (ADS)

    Jarochowska, Emilia; Munnecke, Axel

    2015-01-01

    Stable carbon isotope curves are used as a precise stratigraphic tool in the Paleozoic, even though they are commonly based on shallow-water carbonate record, characterized by low stratigraphic completeness. Identification of episodes of large-scale redeposition and erosion may improve δ13Ccarb-based correlations. Here, a series of at least three episodes of high-energy onshore redeposition are described from the Makarivka Member (new unit) of the Ustya Formation from the Homerian (middle Silurian) of Podolia, Ukraine. The Makarivka Member is emplaced within a tidal flat succession. Its most prominent part is divided into a lower polymictic conglomerate of sand- to boulder-sized clasts representing a range of subtidal facies, and an upper heterolithic unit composed of grainstone and mudstone laminae. The aim of the study is to identify the mechanism of deposition of the allochthonous conglomeratic material in this Member. Based on analogies with recent tsunami deposits, the conglomerate is interpreted to reflect the strongest landward-directed current in the tsunami run-up phase, and the heterolith - alternating high-density landward currents, stagnant intervals allowing mud and land-derived debris to settle, and backwash flows. The tsunamite was deposited during an interval of decreasing isotopic values of the Mulde excursion, a global δ13C excursion reaching + 5.2‰ in the studied sections. Clast redeposition in an interval characterized by rapidly changing δ13Ccarb offers the opportunity to evaluate the degree of temporal and spatial averaging caused by the tsunami. The clasts in the polymictic conglomerate show scattered δ13Ccarb values (- 0.3‰ to + 2.1‰) compared to homogenous (1.3‰ to 1.6‰) values in the matrix. The presence of clasts characterized by low δ13Ccarb values is explained by their decrease with bathymetry rather than erosion of pre-excursion strata, whereas high values characterize material entrained from the sea-floor and strata directly underlying the tsunamite. Close (1.3‰ and 1.5‰) average δ13Ccarb values suggest that the matrix of the conglomerate is potentially a product of clast grinding.

  15. Response to Tendon Vibration Questions the Underlying Rationale of Proprioceptive Training

    PubMed Central

    Lubetzky, Anat Vilnai; McCoy, Sarah Westcott; Price, Robert; Kartin, Deborah

    2017-01-01

    Context: Proprioceptive training on compliant surfaces is used to rehabilitate and prevent ankle sprains. The ability to improve proprioceptive function via such training has been questioned. Achilles tendon vibration is used in motor-control research as a form of proprioceptive stimulus. Using measures of postural steadiness with nonlinear measures to elucidate control mechanisms, tendon vibration can be applied to investigate the underlying rationale of proprioceptive training. Objective: To test whether the effect of vibration on young adults' postural control depended on the support surface. Design: Descriptive laboratory study. Setting: Research laboratory. Patients or Other Participants: Thirty healthy adults and 10 adults with chronic ankle instability (CAI; age range = 18−40 years). Intervention(s): With eyes open, participants stood in bilateral stance on a rigid plate (floor), memory foam, and a Both Sides Up (BOSU) ball covering a force platform. We applied bilateral Achilles tendon vibration for the middle 20 seconds in a series of 60-second trials and analyzed participants' responses from previbration to vibration (pre-vib) and from vibration to postvibration (vib-post). Main Outcome Measure(s): We calculated anterior-posterior excursion of the center of pressure and complexity index derived from the area under multiscale entropy curves. Results: The excursion response to vibration differed by surface, as indicated by a significant interaction of P < .001 for the healthy group at both time points and for the CAI group vib-post. Although both groups demonstrated increased excursion from pre-vib and from vib-post, a decrease was observed on the BOSU. The complexity response to vibration differed by surface for the healthy group (pre-vib, P < .001). The pattern for the CAI group was similar but not significant. Complexity changes vib-post were the same on all surfaces for both groups. Conclusions: Participants reacted less to ankle vibration when standing on the BOSU as compared with the floor, suggesting that proprioceptive training may not be occurring. Different balance-training paradigms to target proprioception, including tendon vibration, should be explored. PMID:28125270

  16. Lateral Ligament Repair and Reconstruction Restore Neither Contact Mechanics of the Ankle Joint nor Motion Patterns of the Hindfoot

    PubMed Central

    Prisk, Victor R.; Imhauser, Carl W.; O'Loughlin, Padhraig F.; Kennedy, John G.

    2010-01-01

    Background: Ankle sprains may damage both the lateral ligaments of the hindfoot and the osteochondral tissue of the ankle joint. When nonoperative treatment fails, operative approaches are indicated to restore both native motion patterns at the hindfoot and ankle joint contact mechanics. The goal of the present study was to determine the effect of lateral ligament injury, repair, and reconstruction on ankle joint contact mechanics and hindfoot motion patterns. Methods: Eight cadaveric specimens were tested with use of robotic technology to apply combined compressive (200-N) and inversion (4.5-Nm) loads to the hindfoot at 0° and 20° of plantar flexion. Contact mechanics at the ankle joint were simultaneously measured. A repeated-measures experiment was designed with use of the intact condition as control, with the other conditions including sectioned anterior talofibular and calcaneofibular ligaments, the Broström and Broström-Gould repairs, and graft reconstruction. Results: Ligament sectioning decreased contact area and caused a medial and anterior shift in the center of pressure with inversion loads relative to those with the intact condition. There were no significant differences in inversion or coupled axial rotation with inversion between the Broström repair and the intact condition; however, medial translation of the center of pressure remained elevated after the Broström repair relative to the intact condition. The Gould modification of the Broström procedure provided additional support to the hindfoot relative to the Broström repair, reducing inversion and axial rotation with inversion beyond that of intact ligaments. There were no significant differences in center-of-pressure excursion patterns between the Broström-Gould repair and the intact ligament condition, but this repair increased contact area beyond that with the ligaments intact. Graft reconstruction more closely restored inversion motion than did the Broström-Gould repair at 20° of plantar flexion but limited coupled axial rotation. Graft reconstruction also increased contact areas beyond the lateral ligament-deficient conditions but altered center-of-pressure excursion patterns relative to the intact condition. Conclusions: No lateral ankle ligament reconstruction completely restored native contact mechanics of the ankle joint and hindfoot motion patterns. Clinical Relevance: Our results provide a rationale for conducting long-term, prospective, comparative, in vivo studies to assess the impact of altered mechanics following lateral ligament injury, and its nonoperative and operative treatment, on the development of ankle osteoarthritis. PMID:20962188

  17. First spacecraft encounter with an asteroid approaches

    NASA Technical Reports Server (NTRS)

    Tholen, David J.

    1991-01-01

    During the course of the Galileo spacecraft's journey to Jupiter it will make two excursions through the steroid belt situated between Mars and Jupiter. The first excursion involves an encounter with the asteroid 951 Gaspra, which will take place on October 29, 1991. Gaspra is a small (about 15 km diameter) asteroid near the outer edge of the main asteroid belt. It's spectral classification is S, suggesting a composition similar to those of stony-iron meteorites. A figure is given showing the brightness of this asteroid as a function of time.

  18. Developing Physiologic Models for Emergency Medical Procedures Under Microgravity

    NASA Technical Reports Server (NTRS)

    Parker, Nigel; O'Quinn, Veronica

    2012-01-01

    Several technological enhancements have been made to METI's commercial Emergency Care Simulator (ECS) with regard to how microgravity affects human physiology. The ECS uses both a software-only lung simulation, and an integrated mannequin lung that uses a physical lung bag for creating chest excursions, and a digital simulation of lung mechanics and gas exchange. METI s patient simulators incorporate models of human physiology that simulate lung and chest wall mechanics, as well as pulmonary gas exchange. Microgravity affects how O2 and CO2 are exchanged in the lungs. Procedures were also developed to take into affect the Glasgow Coma Scale for determining levels of consciousness by varying the ECS eye-blinking function to partially indicate the level of consciousness of the patient. In addition, the ECS was modified to provide various levels of pulses from weak and thready to hyper-dynamic to assist in assessing patient conditions from the femoral, carotid, brachial, and pedal pulse locations.

  19. Developing Physiologic Models for Emergency Medical Procedures Under Microgravity

    NASA Technical Reports Server (NTRS)

    Parker, Nigel; OQuinn, Veronica

    2012-01-01

    Several technological enhancements have been made to METI's commercial Emergency Care Simulator (ECS) with regard to how microgravity affects human physiology. The ECS uses both a software-only lung simulation, and an integrated mannequin lung that uses a physical lung bag for creating chest excursions, and a digital simulation of lung mechanics and gas exchange. METI's patient simulators incorporate models of human physiology that simulate lung and chest wall mechanics, as well as pulmonary gas exchange. Microgravity affects how O2 and CO2 are exchanged in the lungs. Procedures were also developed to take into affect the Glasgow Coma Scale for determining levels of consciousness by varying the ECS eye-blinking function to partially indicate the level of consciousness of the patient. In addition, the ECS was modified to provide various levels of pulses from weak and thready to hyper-dynamic to assist in assessing patient conditions from the femoral, carotid, brachial, and pedal pulse locations.

  20. Thermal-mechanical fatigue test apparatus for metal matrix composites and joint attachments

    NASA Technical Reports Server (NTRS)

    Westfall, L. J.; Petrasek, D. W.

    1985-01-01

    Two thermal-mechanical fatigue (TMF) test facilities were designed and developed, one to test tungsten fiber reinforced metal matrix composite specimens at temperature up to 1430C (2600F) and another to test composite/metal attachment bond joints at temperatures up to 760C (1400 F). The TMF facility designed for testing tungsten fiber reinforced metal matrix composites permits test specimen temperature excursions from room temperature to 1430C (2600F) with controlled heating and loading rates. A strain-measuring device measures the strain in the test section of the specimen during each heating and cooling cycle with superimposed loads. Data is collected and recorded by a computer. The second facility is designed to test composite/metal attachment bond joints and to permit heating to a maximum temperature of 760C (1400F) within 10 min and cooling to 150C (300F) within 3 min. A computer controls specimen temperature and load cycling.

  1. Thermal-mechanical fatigue test apparatus for metal matrix composites and joint attachments

    NASA Technical Reports Server (NTRS)

    Westfall, Leonard J.; Petrasek, Donald W.

    1988-01-01

    Two thermal-mechanical fatigue (TMF) test facilities were designed and developed, one to test tungsten fiber reinforced metal matrix composite specimens at temperature up to 1430C (2600F) and another to test composite/metal attachment bond joints at temperatures up to 760F (1400F). The TMF facility designed for testing tungsten fiber reinforced metal matrix composites permits test specimen temperature excursions from room temperature to 1430C (2600F) with controlled heating and loading rates. A strain-measuring device measures the strain in the test section of the specimen during each heating and cooling cycle with superimposed loads. Data is collected and recorded by a computer. The second facility is designed to test composite/metal attachment bond joints and to permit heating to a maximum temperature of 760C (1400F) within 10 min and cooling to 150C (300F) within 3 min. A computer controls specimen temperature and load cycling.

  2. Osmotic tolerance limits and membrane permeability characteristics of stallion spermatozoa treated with cholesterol.

    PubMed

    Glazar, Amanda I; Mullen, Steven F; Liu, Jun; Benson, James D; Critser, John K; Squires, Edward L; Graham, James K

    2009-10-01

    Stallion spermatozoa exhibit osmotic damage during the cryopreservation process. Recent studies have shown that the addition of cholesterol to spermatozoal membranes increases the cryosurvival of bull, ram and stallion spermatozoa, but the exact mechanism by which added cholesterol improves cryosurvival is not understood. The objectives of this study were to determine if adding cholesterol to stallion sperm membranes alters the osmotic tolerance limits and membrane permeability characteristics of the spermatozoa. In experiment one, stallion spermatozoa were treated with cholesterol-loaded cyclodextrin (CLC), subjected to anisotonic solutions and spermatozoal motility analyzed. The spermatozoa were then returned to isotonic conditions and the percentages of motile spermatozoa again determined. CLC treatment increased the osmotic tolerance limit of stallion spermatozoa in anisotonic solutions and when returned to isotonic conditions. The second and third experiments utilized an electronic particle counter to determine the plasma membrane characteristics of stallion spermatozoa. In experiment two, stallion spermatozoa were determined to behave as linear osmometers. In experiment three, spermatozoa were treated with CLC, incubated with different cryoprotectants (glycerol, ethylene glycol or dimethyl formamide) and their volume excursions measured during cryoprotectant removal at 5 degrees and 22 degrees C. Stallion spermatozoa were less permeable to the cryoprotectants at 5 degrees C than 22 degrees C. Glycerol was the least permeable cryoprotectant in control cells. The addition of CLC's to spermatozoa increased the permeability of stallion spermatozoa to the cryoprotectants. Therefore, adding cholesterol to spermatozoal membranes reduces the amount of osmotic stress endured by stallion spermatozoa during cryopreservation.

  3. Modulating tibiofemoral contact force in the sheep hind limb via treadmill walking: Predictions from an opensim musculoskeletal model.

    PubMed

    Lerner, Zachary F; Gadomski, Benjamin C; Ipson, Allison K; Haussler, Kevin K; Puttlitz, Christian M; Browning, Raymond C

    2015-08-01

    Sheep are a predominant animal model used to study a variety of orthopedic conditions. Understanding and controlling the in-vivo loading environment in the sheep hind limb is often necessary for investigations relating to bone and joint mechanics. The purpose of this study was to develop a musculoskeletal model of an adult sheep hind limb and investigate the effects of treadmill walking speed on muscle and joint contact forces. We constructed the skeletal geometry of the model from computed topography images. Dual-energy x-ray absorptiometry was utilized to establish the inertial properties of each model segment. Detailed dissection and tendon excursion experiments established the requisite muscle lines of actions. We used OpenSim and experimentally-collected marker trajectories and ground reaction forces to quantify muscle and joint contact forces during treadmill walking at 0.25 m• s(-1) and 0.75 m• s(-1) . Peak compressive and anterior-posterior tibiofemoral contact forces were 20% (0.38 BW, p = 0.008) and 37% (0.17 BW, p = 0.040) larger, respectively, at the moderate gait speed relative to the slower speed. Medial-lateral tibiofemoral contact forces were not significantly different. Adjusting treadmill speed appears to be a viable method to modulate compressive and anterior-posterior tibiofemoral contact forces in the sheep hind limb. The musculoskeletal model is freely-available at www.SimTK.org. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  4. Hubble Space Telescope Servicing Mission 3A Rendezvous Operations

    NASA Technical Reports Server (NTRS)

    Lee, S.; Anandakrishnan, S.; Connor, C.; Moy, E.; Smith, D.; Myslinski, M.; Markley, L.; Vernacchio, A.

    2001-01-01

    The Hubble Space Telescope (HST) hardware complement includes six gas bearing, pulse rebalanced rate integrating gyros, any three of which are sufficient to conduct the science mission. After the loss of three gyros between April 1997 and April 1999 due to a known corrosion mechanism, NASA decided to split the third HST servicing mission into SM3A, accelerated to October 1999, and SM3B, scheduled for November 2001. SM3A was developed as a quick turnaround 'Launch on Need' mission to replace all six gyros. Loss of a fourth gyro in November 1999 caused HST to enter Zero Gyro Sunpoint (ZGSP) safemode, which uses sun sensors and magnetometers for attitude determination and momentum bias to maintain attitude stability during orbit night. Several instances of large attitude excursions during orbit night were observed, but ZGSP performance was adequate to provide power-positive sun pointing and to support low gain antenna communications. Body rates in ZGSP were estimated to exceed the nominal 0.1 deg/sec rendezvous limit, so rendezvous operations were restructured to utilize coarse, limited life, Retrieval Mode Gyros (RMGs) under Hardware Sunpoint (HWSP) safemode. Contingency procedures were developed to conduct the rendezvous in ZGSP in the event of RMGA or HWSP computer failure. Space Shuttle Mission STS-103 launched on December 19, 1999 after a series of weather and Shuttle-related delays. After successful rendezvous and grapple under HWSP/RMGA, the crew changed out all six gyros. Following deploy and systems checkout, HST returned to full science operations.

  5. The study of the geomagnetic excursions and the relative intensities from Chinese loess 10Be over the past 130 ka

    NASA Astrophysics Data System (ADS)

    Zhou, W.; Xian, F.; Beck, J.; An, Z.; Wu, Z.; Liu, M.; Chen, M.; Priller, A.; Kutschera, W.; Jull, A. T.; Yu, H.; Song, S.; Cheng, P.; Kong, X.

    2009-12-01

    Chinese loess is well-known archive for the paleogeomagnetic and paleoclimatic studies [Zhou et al., 1990; An et al., 1990; Zhu et al., 2007]. However, earlier efforts to extract weak geomagnetic excursion signals from Chinese loess 10Be were always unsuccessful due to the complexities of loess 10Be, which results in the fact that loess 10Be was only used as a climatic proxy [Shen et al., 1992; Beer et al.,1993; Gu et al.,1996]. Meanwhile, knowledge on the precise stratigraphic horizons of geomagnetic excursions with a reliable dating [Channell, 2006], on whether the short-lived excursions such as Blake can not be recorded in paleosol unit are still controversial. Here, we present the reconstructed past 130ka geomagnetic excursions and relative paleointensities for the first time from 10Be records in two Chinese loess sections. Results are comparative with those of independent geomagnetic research on Atlantic and Pacific sediments. The derived Laschamp and Blake events lie in the loess-paleosol (L1SS1 and S1SS3) corresponding to mid MIS 3 and 5e respectively. Our studies prove the potential application of the complex loess 10Be for long-term geomagnetic tracing and provide new evidence to answer the long-existing debates on the precise stratigraphic horizon of geomagnetic excursions. Our study suggests the potential application of loess-paleosol 10Be for reconstructing geomagnetic intensity variations spanning the whole Quaternary. References 1. Zhou, L. P., F. Oldfield, A. G. Wintle, S. G. Robinson, and J. T. Wang (1990), Partly pedogenic origin of magnetic variations in Chinese loess, Nature, 346, 737-739. 2. An, Z. S., T. S. Liu, Y. C. Lu, S. C. Porter, G. Kukla, X. H. Wu, and Y. M. Hua (1990), The long-term paleomonsoon variation recorded by the loess-paleosol sequence in Central China, Quat. Int., 7-8, 91-95. 3. Zhu, R. X., R. Zhang, C. L. Deng, Y. X. Pan, Q. S. Liu, and Y. B. Sun (2007), Are Chinese loess deposits essentially continuous?, Geophys. Res. Lett., 34, L17306. 4. Shen, C. D., J. Beer, T. S. Liu, H. Oeschger, G. Bonani, M. Suter, and W.Wolfli (1992), 10Be in Chinese loess, Earth Planet. Sci. Lett., 109(1-2), 169-177. 5. Gu, Z. Y., D. Lal, T. S. Liu, J. Southon, M. W. Caffee, Z. T. Guo, and M. Y.Chen (1996), Five million year 10Be record in Chinese loess and red-clay: climate and weathering relationships, Earth Planet. Sci. Lett., 144(1-2), 273-287. 6. Beer, J., C. D. Shen, F. Heller ,T.S. Liu, G. Bonani, B. Dittrich, M. Suter, and P.W. Kubik (1993), 10Be and magnetic susceptibility in Chinese Loess, Geophys. Res. Lett., 20(1), 57-60 7. Channell, J. E. T.(2006), Late Brunhes polarity excursions (Mono Lake, Laschamp, Iceland Basin and Pringle Falls) recorded at ODP Site 919 (Irminger Basin), Earth Planet. Sci. Lett., 244(1-2), 378-393.

  6. Fractionation between inorganic and organic carbon during the Lomagundi (2.22 2.1 Ga) carbon isotope excursion

    NASA Astrophysics Data System (ADS)

    Bekker, A.; Holmden, C.; Beukes, N. J.; Kenig, F.; Eglinton, B.; Patterson, W. P.

    2008-07-01

    The Lomagundi (2.22-2.1 Ga) positive carbon isotope excursion in shallow-marine sedimentary carbonates has been associated with the rise in atmospheric oxygen, but subsequent studies have demonstrated that the carbon isotope excursion was preceded by the rise in atmospheric oxygen. The amount of oxygen released to the exosphere during the Lomagundi excursion is constrained by the average global fractionation between inorganic and organic carbon, which is poorly characterized. Because dissolved inorganic and organic carbon reservoirs were arguably larger in the Paleoproterozoic ocean, at a time of lower solar luminosity and lower ocean redox state, decoupling between these two variables might be expected. We determined carbon isotope values of carbonate and organic matter in carbonates and shales of the Silverton Formation, South Africa and in the correlative Sengoma Argillite Formation, near the border in Botswana. These units were deposited between 2.22 and 2.06 Ga along the margin of the Kaapvaal Craton in an open-marine deltaic setting and experienced lower greenschist facies metamorphism. The prodelta to offshore marine shales are overlain by a subtidal carbonate sequence. Carbonates exhibit elevated 13C values ranging from 8.3 to 11.2‰ vs. VPDB consistent with deposition during the Lomagundi positive excursion. The total organic carbon (TOC) contents range from 0.01 to 0.6% and δ13C values range from - 24.8 to - 13.9‰. Thus, the isotopic fractionation between organic and carbonate carbon was on average 30.3 ± 2.8‰ ( n = 32) in the shallow-marine environment. The underlying Sengoma shales have highly variable TOC contents (0.14 to 21.94%) and δ13C values (- 33.7 to - 20.8‰) with an average of - 27.0 ± 3.0‰ ( n = 50). Considering that the shales were also deposited during the Lomagundi excursion, and taking δ13C values of the overlying carbonates as representative of the δ13C value of dissolved inorganic carbon during shale deposition, a carbon isotope fractionation as large as ~ 37‰ appears to characterize the production of bulk organic matter in the deeper part of the Pretoria Basin at that time. This enhanced fractionation relative to that observed in shallow-water environments likely reflects heterotrophic (secondary) and chemotrophic productivity at and below a pronounced redoxcline, consistent with the euxinic conditions inferred from independent evidence for the deeper part of the Pretoria Basin. Greater variability in organic carbon vs. carbonate carbon isotopic values on the shallow-marine carbonate platform suggests that the carbon cycling was dominated by a large dissolved inorganic carbon reservoir during the Lomagundi excursion. Our study suggests that in contrast to the Late Neoproterozoic and Phanerozoic, when carbon isotope fractionation between carbonate and organic carbon in the open ocean was mostly controlled by primary producers, in the Paleoproterozoic redox-stratified ocean heterotrophic and chemotrophic productivity overprinted a signal of primary productivity below the redoxcline. This strong imprint of heterotrophic and chemotrophic productivity on organic carbon isotope records complicates the reconstruction of spatial patterns and secular trends in the δ13C values of dissolved inorganic carbon in the Paleoproterozoic seawater.

  7. Postmeal exercise blunts postprandial glucose excursions in people on metformin monotherapy.

    PubMed

    Erickson, Melissa L; Little, Jonathan P; Gay, Jennifer L; McCully, Kevin K; Jenkins, Nathan T

    2017-08-01

    Metformin is used clinically to reduce fasting glucose with minimal effects on postprandial glucose. Postmeal exercise reduces postprandial glucose and may offer additional glucose-lowering benefit beyond that of metformin alone, yet controversy exists surrounding exercise and metformin interactions. It is currently unknown how postmeal exercise and metformin monotherapy in combination will affect postprandial glucose. Thus, we examined the independent and combined effects of postmeal exercise and metformin monotherapy on postprandial glucose. A randomized crossover design was used to assess the influence of postmeal exercise on postprandial glucose excursions in 10 people treated with metformin monotherapy (57 ± 10 yr, HbA 1C  = 6.3 ± 0.6%). Each participant completed the following four conditions: sedentary and postmeal exercise (5 × 10-min bouts of treadmill walking at 60% V̇o 2max ) with metformin and sedentary and postmeal exercise without metformin. Peak postprandial glucose within a 2-h time window and 2-h total area under the curve was assessed after a standardized breakfast meal, using continuous glucose monitoring. Postmeal exercise significantly blunted 2-h peak ( P = 0.001) and 2-h area under the curve ( P = 0.006), with the lowest peak postprandial glucose excursion observed with postmeal exercise and metformin combined ( P < 0.05 vs. all other conditions: metformin/sedentary: 12 ± 3.4, metformin/exercise: 9.7 ± 2.3, washout/sedentary: 13.3 ± 3.2, washout/exercise: 11.1 ± 3.4 mmol/l). Postmeal exercise and metformin in combination resulted in the lowest peak postprandial glucose excursion compared with either treatment modality alone. Exercise timed to the postprandial phase may be important for optimizing glucose control during metformin monotherapy. NEW & NOTEWORTHY The interactive effects of metformin and exercise on key physiological outcomes remain an area of controversy. Findings from this study show that the combination of metformin monotherapy and moderate-intensity postmeal exercise led to beneficial reductions in postprandial glucose excursions. Postmeal exercise may be a useful strategy for the management of postprandial glucose in people on metformin. Copyright © 2017 the American Physiological Society.

  8. Glycemic excursions are positively associated with HbA1c reduction from baseline after treatment with acarbose in patients with type 2 diabetes on metformin monotherapy.

    PubMed

    Wang, Jun-Sing; Lee, I-Te; Lee, Wen-Jane; Lin, Shi-Dou; Su, Shih-Li; Tu, Shih-Te; Tseng, Yao-Hsien; Lin, Shih-Yi; Sheu, Wayne Huey-Herng

    2017-03-01

    The aim of the present study was to examine the association between glycemic excursions before treatment and HbA1c reduction after treatment intensification with acarbose or glibenclamide in patients with type 2 diabetes (T2D). Patients receiving single or dual oral antidiabetic drug treatment with an HbA1c of 7.0-11.0 % (53-97 mmol/mol) were switched to metformin monotherapy (500 mg, t.i.d.) for 8 weeks, followed by randomization to either acarbose (100 mg, t.i.d.) or glibenclamide (5 mg, t.i.d.) as add-on treatment for 16 weeks. Glycemic excursions were assessed as mean amplitude of glycemic excursions (MAGE) with 72-h ambulatory continuous glucose monitoring. Treatment efficacy was evaluated as relative HbA1c reduction (%), calculated as (baseline HbA1c - post-treatment HbA1c)/baseline HbA1c × 100. Fifty patients (mean [±SD] age 53.5 ± 8.2 years, 48 % men, mean baseline HbA1c 8.4 ± 1.2 %) were analyzed. Baseline MAGE was positively correlated with relative HbA1c reduction from baseline in patients treated with acarbose (r = 0.421, P = 0.029) but not glibenclamide (r = 0.052, P = 0.813). Linear regression analysis revealed that the association between baseline MAGE and relative HbA1c reduction from baseline (β = 0.125, P = 0.029) in patients treated with acarbose remained significant after adjustment for several confounders (P < 0.05 for all models). In patients with T2D on metformin monotherapy, baseline MAGE was positively correlated with relative HbA1c reduction from baseline after treatment with acarbose, but not glibenclamide. These findings highlight the importance of glycemic excursions in individualized treatment for patients with T2D. © 2016 Ruijin Hospital, Shanghai JiaoTong University School of Medicine (SJTU), Chinese Society of Endocrinology and Chinese Endocrinologist Association and John Wiley & Sons Australia, Ltd.

  9. Prognostic value of early in-hospital glycemic excursion in elderly patients with acute myocardial infarction.

    PubMed

    Su, Gong; Mi, Shu-hua; Li, Zhao; Tao, Hong; Yang, Hong-xia; Zheng, Hong

    2013-02-11

    Acute phase hyperglycemia has been associated with increased mortality in patients with acute myocardial infarction (AMI). However, the predictive value of glycemic excursion for adverse outcome in elderly AMI patients is not clear. The aim of this study is to investigate the prognostic value of early in-hospital glycemic excursion and hemoglobin A1c (HbA1c) for one-year major adverse cardiac event (MACE) in elderly patients with AMI. We studied 186 elderly AMI patients, whose clinical data were collected and the Global Registry of Acute Coronary Events (GRACE) risk score were calculated on admission. The fluctuations of blood glucose in patients were measured by a continuous glucose monitoring system (CGMS) for 72 hours. Participants were grouped into tertiles of mean amplitude of glycemic excursions (MAGE) and grouped into HbA1c levels (as ≥6.5% or <6.5%). The MACE of patients, including new-onset myocardial infarction, acute heart failure and cardiac death, was documented during one year follow-up. The relationship of MAGE and HbA1c to the incidence of MACE in elderly AMI patients was analyzed. In all participants, a higher MAGE level was associated with the higher GRACE score (r = 0.335, p < 0.001). The rate of MACE by MAGE tertiles (>3.94 mmol/L, 2.55-3.94 mmol/L or <2.55 mmol/L) was 30.2% vs. 14.8% vs. 8.1%, respectively (p = 0.004); by HbA1c category (≥6.5% vs. <6.5%) was 22.7% vs. 14.4%, respectively (p = 0.148). Elderly AMI patients with a higher MAGE level had a significantly higher cardiac mortality. In multivariable analysis, high MAGE level was significantly associated with incidence of MACE (HR 3.107, 95% CI 1.190-8.117, p = 0.021) even after adjusting for GRACE risk score, but HbA1c was not. The early in-hospital intraday glycemic excursion may be an important predictor of mortality and MACE even stronger than HbA1c in elderly patients after AMI.

  10. Parallel δ 13C and Conifer Physiognomic Trends Across the Triassic-Jurassic Boundary

    NASA Astrophysics Data System (ADS)

    Whiteside, J. H.; Olsen, P. E.; Sambrotto, R. N.; Cornet, B.

    2003-12-01

    The Triassic-Jurassic mass extinction event ( ˜200 Ma) had a profound effect on biotic evolution, and herein we describe trends in cheirolepidaceous conifer leaf physiognomy from the Pangean tropics (present northeastern USA) that at least broadly parallel a negative δ 13C excursion recorded in the same strata. The physiognomic changes appear at an abrupt (<10 ky) negative carbon isotope excursion (1) synchronous with a previously described palynological extinction level, fern spike, and Ir anomaly (2), and continue through a prolonged negative excursion, lasting 900 ky (through all three CAMP basaltic extrusive events), encompassing most of the Hettangian age. The physiognomic changes seen in the cheirolepidaceous conifer leafy shoot forms Brachyphyllum and Pagiophyllum through the δ 13C excursions include primarily the development of microphyllous leaves with thickened cuticle and sunken papillate stomata (3). These floral modifications are consistent with intense thermal stress plausibly due to very high atmospheric CO2 concentrations and corroborate McElwain's (4) thermal damage hypothesis for the Triassic-Jurassic transition that was originally based on different plant taxa from the higher Pangean latitudes in present Greenland and Sweden. Subsequently, a 2- to 5-fold increase in the area of leafy shoots in strata of latest Hettangian age suggest a return to lower thermal stress levels perhaps due to lower CO2, despite the fact that eastern North America continued to drift into more arid latitudes. The floral physiognomic changes associated with the negative δ 13C excursion and likely very elevated CO2 levels is in many ways a microcosm of the Mesozoic in which the dominance of cheiroleps apparently overlaps with the highest CO2 levels of the Mesozoic (5). References. (1) Whiteside JH, Olsen PE, Sambrotto RN. 2003. Geol. Soc. Amer. Abst. Prog. (in press). (2) Olsen PE et al., Science 296:1305-1307 (3) Cornet B. 1989. in Olsen PE, Schlische RW, Gore PJW, Internat. Geol. Cong., Guidebooks T351, p. 115. (4) McElwain JC, Beerling, DJ, Woodward FI. 1999. Science 285:1386. (5) Ekart D, Cerling TR, Montanez IP, Tabor NJ. 1999. Am. J. Sci. 299:805.

  11. Manifestation of the geomagnetic Mono Lake excursion in sediments of the northern part of the Barents Sea

    NASA Astrophysics Data System (ADS)

    Goos'kova, E.; Volkova, Y.; Piskarev, A.; Morner, N.-A.; Abrahamsen, N.; Dergachev, V.; Raspopov, O.

    2003-04-01

    Palaeomagnetic characteristics of cores from three boreholes (AK-56, AK-87, AK-98) collected in the northern part of the Barents sea (79-80 N) during the expedition of the Research Vessel "Academician Karpinsky" in 1998 have been studied. The cores were taken from depths of 329, 377, and 473 m, respectively. In all three cores, changes in inclination from -80 to -150 degrees were observed at a depth of 110-130 cm (in 6-8 core samples), which suggests that this phenomenon can be attributed to a geomagnetic field excursion. Basing on dating of the lithologic Holocene-Pleistocene boundary, the sedimentation rate in this part of the Barents Sea can be estimated to be 5-7 cm/1000 years. In this case the age of the excursion is about 24 000 BP, i.e., it corresponds to the Mono Lake excursion. In the Barents Sea sediments, the manifestation of this excursion was revealed for the first time in the ACB-2 core taken in the central part of the sea. At a depth of 150-180 cm, all three cores (in 8-10 samples) were found to have a layer with abnormally high natural remanent magnetization (up to 6-11 nT with a mean value of 1.5 nT) and magnetic susceptibility (up to 1.0-1.7 x 10-3 SI with a mean value of 0.4 x 10-3 SI). Basing on lithological data, the time of formation of this layer can be estimated as approximately 30 000 - 35 000 BP. A reference layer at the depth corresponding to the Holocene-Pleistocene boundary with similar changes in magnetic susceptibility attributed to climate change was found in the cores taken from the central part of the Barents sea earlier. It is likely that sharp changes in magnetic properties of sediments in the northern part of the Barents Sea about 30 000 - 35 000 BP are also attributable to a sharp climate change (warming) during that period of time. This work was supported by INTAS, Grant 97-31008 and PFBR, Grant 00-05-64921.

  12. Prognostic Value of Right Ventricular Dysfunction in Heart Failure With Reduced Ejection Fraction: Superiority of Longitudinal Strain Over Tricuspid Annular Plane Systolic Excursion.

    PubMed

    Carluccio, Erberto; Biagioli, Paolo; Alunni, Gianfranco; Murrone, Adriano; Zuchi, Cinzia; Coiro, Stefano; Riccini, Clara; Mengoni, Anna; D'Antonio, Antonella; Ambrosio, Giuseppe

    2018-01-01

    In heart failure (HF) with reduced ejection fraction, right ventricular (RV) impairment, as defined by reduced tricuspid annular plane systolic excursion, is a predictor of poor outcome. However, peak longitudinal strain of RV free wall (RVFWS) has been recently proposed as a more accurate and sensitive tool to evaluate RV function. Accordingly, we investigated whether RVFWS could help refine prognosis of patients with HF with reduced ejection fraction in whom tricuspid annular plane systolic excursion is still preserved. A total of 200 patients with HF with reduced ejection fraction (age, 66±11 years; ejection fraction, 30±7%) with preserved tricuspid annular plane systolic excursion (>16 mm) underwent RV function assessment using speckle-tracking echocardiography to measure peak RVFWS. After a median follow-up period of 28 months, 62 (31%) patients reached the primary composite end point of all-cause death/HF rehospitalization. Median RVFWS was -19.3% (interquartile range, -23.3% to -15.0%). By lasso-penalized Cox-hazard model, RVFWS was an independent predictor of outcome, along with Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure-HF score, Echo-HF score, and severe mitral regurgitation. The best cutoff value of RVFWS for prediction of outcome was -15.3% (area under the curve, 0.68; P <0.001; sensitivity, 50%; specificity, 80%). In 50 patients (25%), RVFWS was impaired (ie, ≥-15.3%); event rate (per 100 patients per year) was greater in them than in patients with RVFWS <-15.3% (29.5% [95% confidence interval, 20.4-42.7] versus 9.4% [95% confidence interval, 6.7-13.1]; P <0.001). RVFWS yielded a significant net reclassification improvement (0.584 at 3 years; P <0.001), with 68% of nonevents correctly reclassified. In patients with HF with reduced ejection fraction with preserved tricuspid annular plane systolic excursion, RV free-wall strain provides incremental prognostic information and improved risk stratification. © 2018 American Heart Association, Inc.

  13. Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients.

    PubMed

    Mukherjee, Monica; Chung, Shang-En; Ton, Von Khue; Tedford, Ryan J; Hummers, Laura K; Wigley, Fredrick M; Abraham, Theodore P; Shah, Ami A

    2016-06-01

    Cardiac involvement in systemic sclerosis (scleroderma [SSc]) adversely affects long-term prognosis, often remaining undetectable despite close clinical examination and 2-dimensional echocardiographic monitoring. Speckle-derived strain of the right ventricle (RV) was utilized to detect occult abnormalities in regional and global contractility in SSc patients. A total of 138 SSc patients with technically adequate echocardiograms was studied and compared with 40 age- and sex-matched healthy non-SSc controls. Standard assessment of RV chamber function included tricuspid annular plane systolic excursion and fractional area change. RV longitudinal systolic speckle-derived strain was assessed in the basal, mid, and apical free wall. Tricuspid annular plane systolic excursion was not different between groups (P=0.307). Although fractional area change was lower in SSc patients than in controls (mean, 48.9 versus 55; P=0.002), the mean fractional area change was still within the normal range (>35). In contrast, RV longitudinal systolic speckle-derived strain measures were significantly different between groups, both globally (-20.4% versus -17.7%; P=0.005) and regionally: they were decreased in the apex (-8.5% versus -17.1%; P<0.0001) and mid segments (-12.4% versus -20.9%; P<0.0001), and increased in the base (-32.2% versus -23.3%; P=0.0001) for the SSc group. The regional difference in the base compared with the apex was significantly greater for SSc than for controls (P<0.0001 for interaction). The differences observed in regional strain between SSc and control were unchanged after adjusting for RV systolic pressure. Speckle-derived strain reveals a heterogenous pattern of regional heart strain in SSc that is not detected by conventional measures of function, suggestive of occult RV myocardial disease. © 2016 American Heart Association, Inc.

  14. Association of serum orosomucoid with 30-min plasma glucose and glucose excursion during oral glucose tolerance tests in non-obese young Japanese women.

    PubMed

    Tsuboi, Ayaka; Minato, Satomi; Yano, Megumu; Takeuchi, Mika; Kitaoka, Kaori; Kurata, Miki; Yoshino, Gen; Wu, Bin; Kazumi, Tsutomu; Fukuo, Keisuke

    2018-01-01

    Inflammatory markers are elevated in insulin resistance (IR) and diabetes. We tested whether serum orosomucoid (ORM) is associated with postload glucose, β-cell dysfunction and IR inferred from plasma insulin kinetics during a 75 g oral glucose tolerance test (OGTT). 75 g OGTTs were performed with multiple postload glucose and insulin measurements over a 30-120 min period in 168 non-obese Japanese women (aged 18-24 years). OGTT responses, serum adiponectin and high-sensitivity C reactive protein (hsCRP) were cross-sectionally analyzed by analysis of variance and then Bonferroni's multiple comparison procedure. Stepwise multivariate linear regression analyses were used to identify most important determinants of ORM. Of 168 women, 161 had normal glucose tolerance. Postload glucose levels and the area under the glucose curve (AUCg) increased in a stepwise fashion from the first through the third ORM tertile. In contrast, there was no or modest, if any, association with fat mass index, trunk/leg fat ratio, adiponectin, hsCRP, postload insulinemia, the Matsuda index and homeostasis model assessment IR. In multivariable models, which incorporated the insulinogenic index, the Matsuda index and HOMA-IR, 30 min glucose (standardized β: 0.517) and AUCg (standardized β: 0.495) explained 92.8% of ORM variations. Elevated circulating orosomucoid was associated with elevated 30 min glucose and glucose excursion in non-obese young Japanese women independently of adiposity, IR, insulin secretion, adiponectin and other investigated markers of inflammation. Although further research is needed, these results may suggest a clue to identify novel pathways that may have utility in monitoring dysglycemia within normal glucose tolerance.

  15. Mobility assessment: Sensitivity and specificity of measurement sets in older adults

    PubMed Central

    Panzer, Victoria P.; Wakefield, Dorothy B.; Hall, Charles B.; Wolfson, Leslie I.

    2011-01-01

    Objective To identify quantitative measurement variables that characterize mobility in older adults, meet reliability and validity criteria, distinguish fall-risk and predict future falls. Design Observational study with 1-year weekly falls follow-up Setting Mobility laboratory Participants Community-dwelling volunteers (n=74; 65–94 years old) categorized at entry as 27 ‘Non-fallers’ or 47 ‘Fallers’ by Medicare criteria (1 injury fall or >1 non-injury falls in the previous year). Interventions None Outcome Measures Test-retest and within-subject reliability, criterion and concurrent validity; predictive ability indicated by observed sensitivity and specificity to entry fall-risk group (Falls-status), Tinetti Performance Oriented Mobility Assessment (POMA), Computerized Dynamic Posturography Sensory Organization Test (SOT) and subsequent falls reported weekly. Results Measurement variables were selected that met reliability (ICC > 0.6) and/or discrimination (p<.01) criteria (Clinical variables- Turn- steps, time, Gait- velocity, Step-in-tub-time, and Downstairs- time; Force plate variables- Quiet standing Romberg ratio sway-area, Maximal lean- anterior-posterior excursion, Sit-to-stand medial-lateral excursion and sway-area). Sets were created (3 clinical, 2 force plate) utilizing combinations of variables appropriate for older adults with different functional activity levels and composite scores were calculated. Scores identified entry Falls-status and concurred with POMA and SOT. The Full clinical set (5 measurement variables) produced sensitivity/specificity (.80/.74) to Falls-status. Composite scores were sensitive and specific in predicting subsequent injury falls and multiple falls compared to Falls-status, POMA or SOT. Conclusions Sets of quantitative measurement variables obtained with this mobility battery provided sensitive prediction of future injury falls and screening for multiple subsequent falls using tasks that should be appropriate to diverse participants. PMID:21621667

  16. Is most of the Tommotian missing in the White-Inyo region eastern California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Corsetti, F.A.

    Integration of carbon-isotope chemostratigraphic data with trace fossil assemblages suggests that a significant hiatus may be present within the Lower Member of the Deep Spring Formation, potentially impacting the placement of the Neoproterozoic-Cambrian boundary in eastern California and western Nevada. A positive carbon-isotopic excursion of 4% PDB is present in the lowermost Lower Deep Spring, and is associated with Zone 1 trace fossils (latest Vendian) and small shelly fossils of disputed age (latest Proterozoic or Tommotian). A negative isotopic excursion is observed throughout the remaining Deep Spring Formation, and is associated with Zone 3 trace fossils (latest Tommotian-Atdabanian in age).more » The positive excursion in the lowermost Deep Spring is tentatively correlated with the pronounced isotopic maximum in the latest Vendian (possibly Nemakit-Daldyn) of the Siberian Platform (cycle 1 of Kirshvink et al., 1991). The negative excursion is correlated with a similar trend in the latest Tommotian-Atdabanian of the Siberian Platform (cycle 4 of Kirshvink et al., 1991). Thus, a hiatus, potentially encompassing most of the Tommotian, is postulated to be present within the Lower Member of the Deep Spring Formation. Although the fossil and isotopic data are consistent with the presence of a break in the section, sedimentological field evidence for the hiatus is somewhat cryptic. The recognition of this hiatus may impact the global significance of the presumed Tommotian small shelly fossils of the White-Inyo region, as well as the placement of the Neoproterozoic-Cambrian boundary in this sequence.« less

  17. Modelling tendon excursions and moment arms of the finger flexors: anatomic fidelity versus function.

    PubMed

    Kociolek, Aaron M; Keir, Peter J

    2011-07-07

    A detailed musculoskeletal model of the human hand is needed to investigate the pathomechanics of tendon disorders and carpal tunnel syndrome. The purpose of this study was to develop a biomechanical model with realistic flexor tendon excursions and moment arms. An existing upper extremity model served as a starting point, which included programmed movement of the index finger. Movement capabilities were added for the other fingers. Metacarpophalangeal articulations were modelled as universal joints to simulate flexion/extension and abduction/adduction while interphalangeal articulations used hinges to represent flexion. Flexor tendon paths were modelled using two approaches. The first method constrained tendons with control points, representing annular pulleys. The second technique used wrap objects at the joints as tendon constraints. Both control point and joint wrap models were iteratively adjusted to coincide with tendon excursions and moment arms from a anthropometric regression model using inputs for a 50th percentile male. Tendon excursions from the joint wrap method best matched the regression model even though anatomic features of the tendon paths were not preserved (absolute differences: mean<0.33 mm, peak<0.74 mm). The joint wrap model also produced similar moment arms to the regression (absolute differences: mean<0.63 mm, peak<1.58 mm). When a scaling algorithm was used to test anthropometrics, the scaled joint wrap models better matched the regression than the scaled control point models. Detailed patient-specific anatomical data will improve model outcomes for clinical use; however, population studies may benefit from simplified geometry, especially with anthropometric scaling. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Evaluation of diaphragmatic motion in normal and diaphragmatic paralyzed dogs using M-mode ultrasonography.

    PubMed

    Choi, Mihyun; Lee, Namsoon; Kim, Ahyoung; Keh, Seoyeon; Lee, Jinsoo; Kim, Hyunwook; Choi, Mincheol

    2014-01-01

    Diagnosis of unilateral diaphragmatic paralysis in dogs is currently based on fluoroscopic detection of unequal movement between the crura. Bilateral paralysis may be more difficult to confirm with fluoroscopy because diaphragmatic movement is sometimes produced by compensatory abdominal muscle contractions. The purpose of this study was to develop a new method to evaluate diaphragmatic movement using M-mode ultrasonography and to describe findings for normal and diaphragmatic paralyzed dogs. Fifty-five clinically normal dogs and two dogs with diaphragmatic paralysis were recruited. Thoracic radiographs were acquired for all dogs and fluoroscopy studies were also acquired for clinically affected dogs. Two observers independently measured diaphragmatic direction of motion and amplitude of excursion using M-mode ultrasonography for dogs meeting study inclusion criteria. Eight of the clinically normal dogs were excluded due to abnormal thoracic radiographic findings. For the remaining normal dogs, the lower limit values of diaphragmatic excursion were 2.85-2.98 mm during normal breathing. One dog with bilateral diaphragmatic paralysis showed paradoxical movement of both crura at the end of inspiration. One dog with unilateral diaphragmatic paralysis had diaphragmatic excursion values of 2.00 ± 0.42 mm on the left side and 4.05 ± 1.48 mm on the right side. The difference between left and right diaphragmatic excursion values was 55%. Findings indicated that M-mode ultrasonography is a relatively simple and objective method for measuring diaphragmatic movement in dogs. Future studies are needed in a larger number of dogs with diaphragmatic paralysis to determine the diagnostic sensitivity of this promising new technique. © 2013 American College of Veterinary Radiology.

  19. Forefoot-rearfoot coupling patterns and tibial internal rotation during stance phase of barefoot versus shod running.

    PubMed

    Eslami, Mansour; Begon, Mickaël; Farahpour, Nader; Allard, Paul

    2007-01-01

    Based on twisted plate and mitered hinge models of the foot and ankle, forefoot-rearfoot coupling motion patterns can contribute to the amount of tibial rotation. The present study determined the differences of forefoot-rearfoot coupling patterns as well as excessive excursion of tibial internal rotation in shod versus barefoot conditions during running. Sixteen male subjects ran 10 times at 170 steps per minute under the barefoot and shod conditions. Forefoot-rearfoot coupling motions were assessed by measuring mean relative phase angle during five intervals of stance phase for the main effect of five time intervals and two conditions (ANOVA, P<0.05). Tibial internal rotation excursion was compared between the shod and barefoot conditions over the first 50% of stance phase using paired t-test, (P<0.05). Forefoot adduction/abduction and rearfoot eversion/inversion coupling motion patterns were significantly different between the conditions and among the intervals (P<0.05; effect size=0.47). The mean absolute relative angle was significantly modified to 37 degrees in-phase relationship at the heel-strike of running with shoe wears. No significant differences were noted in the tibial internal rotation excursion between shod and barefoot conditions. Significant variations in the forefoot adduction/abduction and rearfoot eversion/inversion coupling patterns could have little effect on the amount of tibial internal rotation excursion. Yet it remains to be determined whether changes in the frontal plane forefoot-rearfoot coupling patterns influence the tibia kinematics for different shoe wears or foot orthotic interventions. The findings question the rational for the prophylactic use of forefoot posting in foot orthoses.

  20. National facilities study. Volume 3: Mission and requirements model report

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The National Facility Study (NFS) was initiated in 1992 by Daniel S. Goldin, Administrator of NASA as an initiative to develop a comprehensive and integrated long-term plan for future facilities. The resulting, multi-agency NFS consisted of three Task Groups: Aeronautics, Space Operations, and Space Research and Development (R&D) Task Groups. A fourth group, the Engineering and Cost Analysis Task Group, was subsequently added to provide cross-cutting functions, such as assuring consistency in developing an inventory of space facilities. Space facilities decisions require an assessment of current and future needs. Therefore, the two task groups dealing with space developed a consistent model of future space mission programs, operations and R&D. The model is a middle ground baseline constructed for NFS analytical purposes with excursions to cover potential space program strategies. The model includes three major sectors: DOD, civilian government, and commercial space. The model spans the next 30 years because of the long lead times associated with facilities development and usage. This document, Volume 3 of the final NFS report, is organized along the following lines: Executive Summary -- provides a summary view of the 30-year mission forecast and requirements baseline, an overview of excursions from that baseline that were studied, and organization of the report; Introduction -- provides discussions of the methodology used in this analysis; Baseline Model -- provides the mission and requirements model baseline developed for Space Operations and Space R&D analyses; Excursions from the baseline -- reviews the details of variations or 'excursions' that were developed to test the future program projections captured in the baseline; and a Glossary of Acronyms.

  1. An activity index for geomagnetic paleosecular variation, excursions, and reversals

    NASA Astrophysics Data System (ADS)

    Panovska, S.; Constable, C. G.

    2017-04-01

    Magnetic indices provide quantitative measures of space weather phenomena that are widely used by researchers in geomagnetism. We introduce an index focused on the internally generated field that can be used to evaluate long term variations or climatology of modern and paleomagnetic secular variation, including geomagnetic excursions, polarity reversals, and changes in reversal rate. The paleosecular variation index, Pi, represents instantaneous or average deviation from a geocentric axial dipole field using normalized ratios of virtual geomagnetic pole colatitude and virtual dipole moment. The activity level of the index, σPi, provides a measure of field stability through the temporal standard deviation of Pi. Pi can be calculated on a global grid from geomagnetic field models to reveal large scale geographic variations in field structure. It can be determined for individual time series, or averaged at local, regional, and global scales to detect long term changes in geomagnetic activity, identify excursions, and transitional field behavior. For recent field models, Pi ranges from less than 0.05 to 0.30. Conventional definitions for geomagnetic excursions are characterized by Pi exceeding 0.5. Strong field intensities are associated with low Pi unless they are accompanied by large deviations from axial dipole field directions. σPi provides a measure of geomagnetic stability that is modulated by the level of PSV or frequency of excursional activity and reversal rate. We demonstrate uses of Pi for paleomagnetic observations and field models and show how it could be used to assess whether numerical simulations of the geodynamo exhibit Earth-like properties.

  2. The Effect of Pilates Exercise on Trunk and Postural Stability and Throwing Velocity in College Baseball Pitchers: Single Subject Design

    PubMed Central

    Howe, Katherine

    2007-01-01

    Background Baseball pitchers need trunk strength to maximize performance. The Pilates method of exercise is gaining popularity throughout the country as a fitness and rehabilitation method of exercise. However, very few studies exist that examine the effects of the Pilates method of exercise on trunk strength or performance. Objectives Using a single subject, multiple baseline across subjects design, this study examines the effects of the Pilates method of exercise on performance of double leg lowering, star excursion balance test, and throwing velocity in college-aged baseball pitchers. Methods A convenience sample of three college baseball pitchers served as the subjects for this single subject design study. For each subject, double leg lowering, star excursion balance test, and throwing speed were measured prior to the introduction of the intervention. When baseline test values showed consistent performance, the intervention was introduced to one subject at a time. Intervention was introduced to the other subjects over a period of 4 weeks as they also demonstrated consistent performance on the baseline tests. Intervention was continued with periodic tests for the remainder of the 10 week trial. Results Each subject improved in performance on double leg lowering (increased 24.43-32.7%) and star excursion balance test (increased 4.63-17.84%) after introduction of the intervention. Throwing speed improved in two of the three subjects (up to 5.61%). Discussion and Conclusions The Pilates method of exercise may contribute to improved performance in double leg lowering, star excursion balance tests, and throwing speed in college baseball pitchers. PMID:21522199

  3. The impact of round window vs cochleostomy surgical approaches on interscalar excursions in the cochlea: Preliminary results from a flat-panel computed tomography study.

    PubMed

    Jiam, Nicole T; Limb, Charles J

    2016-09-01

    To evaluate incidence of interscalar excursions between round window (RW) and cochleostomy approaches for cochlear implant (CI) insertion. This was a retrospective case-comparison. Flat-panel CT (FPCT) scans for 8 CI users with Med-El standard length electrode arrays were collected. Surgical technique was identified by a combination of operative notes and FPCT imaging. Four cochleae underwent round window insertion and 4 cochleae underwent cochleostomy approaches anterior and inferior to the round window. In our pilot study, cochleostomy approaches were associated with a higher likelihood of interscalar excursion. Within the cochleostomy group, we found 29% of electrode contacts (14 of 48 electrodes) to be outside the scala tympani. On the other hand, 8.5% of the electrode contacts (4 of 47 electrodes) in the round window insertion group were extra-scalar to the scala tympani. These displacements occurred at a mean angle of occurrence of 364° ± 133°, near the apex of the cochlea. Round window electrode displacements tend to localize at angle of occurrences of 400° or greater. Cochleostomy electrodes occurred at an angle of occurrence of 19°-490°. Currently, the optimal surgical approach for standard CI electrode insertion is highly debated, to a certain extent due to a lack of post-operative assessment of intracochlear electrode contact. Based on our preliminary findings, cochleostomy approach is associated with an increased likelihood of interscalar excursions, and these findings should be further evaluated with future prospective studies.

  4. Measurements of Eustachian tube dilation by video endoscopy.

    PubMed

    Poe, Dennis S; Pyykkö, Ilmari

    2011-07-01

    1. To create techniques for measurement of parameters of Eustachian tube (ET) dilation as observed with video endoscopy. 2. To study correlations of the parameters between healthy subjects and patients with ET dysfunction to determine if they may be important for clinical or investigational use. Prospective study in an academic center. 3 groups of adults: healthy subjects, otitis media with effusion (OME), patulous ET. Video software analyses were performed on video recordings from subjects' transnasal endoscopy to measure parameters of the tubal dilation cycle. 24 ETs of 15 healthy subjects, 24 ETs of 15 patulous ET and 20 ETs of 13 OME patients. Mean values for healthy subjects: cycle time 995 ms (SD 404.7), valve opening time 10.5 ms (SD 6.34), torus rotation time 176 ms (SD 151.5 and angle of torus rotation 34.2° (SD 14.3). Palatal elevation, measured as a percentage of torus height was 34.8% (SD 16.6) and excursion of the antero-lateral wall 35.5 % (SD 16.3). Lateral excursion of the antero-lateral wall was significantly less in patulous ET (18.7%, SD 15.1, p = 0.001) and in dilatory dysfunction (23.9%, SD 21.7, p = 0.048). The other parameters were not statistically different between healthy subjects and patients. Lateral excursion of the ET's antero-lateral wall was significantly reduced in OME and patulous ET patients compared with healthy subjects. Evaluation of the excursion of the lateral wall of the ET, which is due to TVP muscle action, may be an important parameter for further clinical and research study.

  5. Sedimentary evidence for enhanced hydrological cycling in response to rapid carbon release during the early Toarcian oceanic anoxic event

    NASA Astrophysics Data System (ADS)

    Izumi, Kentaro; Kemp, David B.; Itamiya, Shoma; Inui, Mutsuko

    2018-01-01

    A pronounced excursion in the carbon-isotope composition of biospheric carbon and coeval seawater warming during the early Toarcian (∼183 Ma) has been linked to the large-scale transfer of 12C-enriched carbon to the oceans and atmosphere. A European bias in the distribution of available data means that the precise pattern, tempo and global expression of this carbon cycle perturbation, and the associated environmental responses, remain uncertain. Here, we present a new cm-scale terrestrial-dominated carbon-isotope record through an expanded lower Toarcian section from Japan that displays a negative excursion pattern similar to marine and terrestrial carbon-isotope records documented from Europe. These new data suggest that 12C-enriched carbon was added to the biosphere in at least one rapid, millennial-scale pulse. Sedimentological analysis indicates a close association between the carbon-isotope excursion and high-energy sediment transport and enhanced fluvial discharge. Together, these data support the hypothesis that a sudden strengthening of the global hydrological cycle occurred in direct and immediate response to rapid carbon release and atmospheric warming.

  6. Fatigue-induced changes in decline running.

    PubMed

    Mizrahi, J; Verbitsky, O; Isakov, E

    2001-03-01

    Study the relation between muscle fatigue during eccentric muscle contractions and kinematics of the legs in downhill running. Decline running on a treadmill was used to acquire data on shock accelerations, muscle activity and kinematics, for comparison with level running. In downhill running, local muscle fatigue is the cause of morphological muscle damage which leads to reduced attenuation of shock accelerations. Fourteen subjects ran on a treadmill above level-running anaerobic threshold speed for 30 min, in level and -4 degrees decline running. The following were monitored: metabolic fatigue by means of respiratory parameters; muscle fatigue of the quadriceps by means of elevation in myoelectric activity; and kinematic parameters including knee and ankle angles and hip vertical excursion by means of computerized videography. Data on shock transmission reported in previous studies were also used. Quadriceps fatigue develops in parallel to an increasing vertical excursion of the hip in the stance phase of running, enabled by larger dorsi flexion of the ankle rather than by increased flexion of the knee. The decrease in shock attenuation can be attributed to quadriceps muscle fatigue in parallel to increased vertical excursion of the hips.

  7. Physiological asymmetry of trunk ranging and pelvis motility: an anatomo-functional study in 80 healthy subjects.

    PubMed

    Macchi, Claudio; Biricolti, Claudia; Cappelli, Lorenza; Galli, Francesca; Molino-Lova, Raffaele; Cecchi, Francesca; Corigliano, Alvaro; Miniati, Benedetta; Conti, Andrea A; Gulisano, Massimo; Catini, Claudio; Gensini, Gian Franco

    2002-01-01

    A key feature in physiotherapeutic treatment of patients with motion disturbances is the appropriate ranging of the trunk and pelvis motility. Eighty subjects randomly selected and free from known pathology of the muscular-skeletal and/or of the neurological system classed into four groups according to the age and the sex have been assessed, by using a new, simple and easy administrable tool. Our results demonstrate that the new measurement tool showed a very low intra- and inter-observer variability, that healthy subjects showed a more adduced and elevated right scapula if compared to the contralateral one and, as regard as the pelvic motion, a broader joint excursion in passive motion compared with active motion in the overall group, a broader joint excursion in young subjects compared with elderly ones, and a broader joint excursion in female subjects compared with males subjects. In conclusion our study allowed to identify a range of physiological asymmetry and pelvis motility. Such a range of physiological asymmetry might be useful as a reference for the physiotherapists.

  8. Mercury enrichment indicates volcanic triggering of Valanginian environmental change

    NASA Astrophysics Data System (ADS)

    Charbonnier, Guillaume; Morales, Chloé; Duchamp-Alphonse, Stéphanie; Westermann, Stéphane; Adatte, Thierry; Föllmi, Karl B.

    2017-01-01

    The Valanginian stage (Early Cretaceous) includes an episode of significant environmental changes, which are well defined by a positive δ13C excursion. This globally recorded excursion indicates important perturbations in the carbon cycle, which has tentatively been associated with a pulse in volcanic activity and the formation of the Paraná-Etendeka large igneous province (LIP). Uncertainties in existing age models preclude, however, its positive identification as a trigger of Valanginian environmental changes. Here we report that in Valanginian sediments recovered from a drill core in Wąwał (Polish Basin, Poland), and from outcrops in the Breggia Gorge (Lombardian Basin, southern Switzerland), and Orpierre and Angles (Vocontian Basin, SE France), intervals at or near the onset of the positive δ13C excursion are significantly enriched in mercury (Hg). The persistence of the Hg anomaly in Hg/TOC, Hg/phyllosilicate, and Hg/Fe ratios shows that organic-matter scavenging and/or adsorbtion onto clay minerals or hydrous iron oxides only played a limited role. Volcanic outgassing was most probably the primary source of the Hg enrichments, which demonstrate that an important magmatic pulse triggered the Valanginian environmental perturbations.

  9. Predictable "individual differences" in uptake and excretion of gases and lipid soluble vapours simulation study.

    PubMed Central

    Fiserova-Bergerova, V; Vlach, J; Cassady, J C

    1980-01-01

    A five-compartment pharmacokinetic model with two excretory pathways, exhalation and metabolism, based on first order kinetics is used to outline the effect of body build, pulmonary ventilation, and lipid content in blood on uptake, distribution, and clearance of low solubility gases and lipid soluble vapours during and after exposure. The model shows the extent that individual differences have on altering uptake and distribution, with consequent changes in blood concentration, rate of excretion, and toxicity, even when variations in these parameters are within physiological ranges. The model is also used to describe the concentration variation of inhaled substances in tissues of subjects exposed to concentrations with permitted excursions. During the same course of exposure, the tissue concentrations of low solubility gases fluctuate much more than tissue concentrations of lipid soluble vapours. The fluctuation is reduced by metabolism of inhaled substance. These conclusions are recommended for consideration whenever evaluating the effect of excursions above the threshold limit values used in the control of industrial exposures (by excursion factors). PMID:7370192

  10. Introductory geology for elementary education majors utilizing a constructivist approach

    USGS Publications Warehouse

    Brown, L.M.; Kelso, P.R.; Rexroad, C.B.

    2001-01-01

    "Field Excursions in Earth Science" is designed as a non-prerequisite field-based course for elementary education majors. Classic Canadian Shield and Michigan Basin outcrops and Quaternary features are used to teach those Earth science objectives considered most important for K-8 teachers by the Michigan State Board of Education and by others. We integrated these objectives into five conceptual pathways rather than presenting them as discrete pieces of information. A variety of teaching techniques based on constructivist educational theory are employed, so that pre-service teachers experience active-learning strategies in the context of how science is practiced. Our learning strategies address the cognitive and affective domains and utilize personal experiences in conjunction with pre- and post-experience organizers to allow students to develop individual meanings. We place emphasis on observations and concepts and we encourage students to explain their understanding of concepts verbally and in a variety of written formats. Activities address spatial concepts and map reading; mineral, rock, and fossil identification; formation of rocks; surficial processes and landform development; structural deformation and plate tectonics; and environmental issues. Students keep field notes and have daily projects. They address the pedagogical structure of the course in a daily diary.

  11. Jaw-muscle fiber architecture in tufted capuchins favors generating relatively large muscle forces without compromising jaw gape.

    PubMed

    Taylor, Andrea B; Vinyard, Christopher J

    2009-12-01

    Tufted capuchins (sensu lato) are renowned for their dietary flexibility and capacity to exploit hard and tough objects. Cebus apella differs from other capuchins in displaying a suite of craniodental features that have been functionally and adaptively linked to their feeding behavior, particularly the generation and dissipation of relatively large jaw forces. We compared fiber architecture of the masseter and temporalis muscles between C. apella (n=12) and two "untufted" capuchins (C. capucinus, n=3; C. albifrons, n=5). These three species share broadly similar diets, but tufted capuchins occasionally exploit mechanically challenging tissues. We tested the hypothesis that tufted capuchins exhibit architectural properties of their jaw muscles that facilitate relatively large forces including relatively greater physiologic cross-sectional areas (PCSA), more pinnate fibers, and lower ratios of mass to tetanic tension (Mass/P(0)). Results show some evidence supporting these predictions, as C. apella has relatively greater superficial masseter and temporalis PCSAs, significantly so only for the temporalis following Bonferroni adjustment. Capuchins did not differ in pinnation angle or Mass/P(0). As an architectural trade-off between maximizing muscle force and muscle excursion/contraction velocity, we also tested the hypothesis that C. apella exhibits relatively shorter muscle fibers. Contrary to our prediction, there are no significant differences in relative fiber lengths between tufted and untufted capuchins. Therefore, we attribute the relatively greater PCSAs in tufted capuchins primarily to their larger muscle masses. These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella. By enlarging jaw-muscle mass to increase PCSA, rather than reducing fiber lengths and increasing pinnation, tufted capuchins appear to have increased jaw-muscle and bite forces without markedly compromising muscle excursion and contraction velocity. One performance advantage of this morphology is that it promotes relatively large bite forces at wide jaw gapes, which may be useful for processing large food items along the posterior dentition. We further hypothesize that this morphological pattern may have the ecological benefit of facilitating the dietary diversity seen in tufted capuchins. Lastly, the observed feeding on large objects, coupled with a jaw-muscle architecture that facilitates this behavior, raises concerns about utilizing C. apella as an extant behavioral model for hominins that might have specialized on small objects in their diets.

  12. Shelf-Slope Exchanges near Submarine Canyons in the Southern Mid-Atlantic Bight

    NASA Astrophysics Data System (ADS)

    Wang, H.; Gong, D.

    2016-02-01

    Shelf-slope exchange processes are major physical drivers of biological productivity near the shelf-break. Observations from two Slocum ocean gliders in Fall 2013 are used to explore the driving mechanisms of cross-shelf-slope exchanges near Norfolk Canyon and Washington Canyon in the southern Mid-Atlantic Bight. Offshore excursion of bottom "cold pool" water, and shoreward intrusion of slope water at surface layer and thermocline depth occurred during northeasterly along-shelf winds. The saline intrusions of surface slope water resided between the cold pool and surface shelf water, and reached the bottom on the outer and mid-shelf, while the offshore excursion of cold pool water was found between the surface and intermediate slope-water over the canyon. Ekman transport calculation shows wind-driven cross-shelf transport can partially explain this interleaving pattern of intrusions. Scaling analysis of double diffusive processes demonstrate that they also likely played a role in the cross-shelf-slope exchange. A unique canyon upwelling event was captured in and around Washington Canyon during a period of southwesterly along-shelf wind and along-shelf flow to the northeast. The water mass distributions and isopycnal responses in both along-canyon and cross-canyon transects are consistent with scaling analysis and numerical studies of canyon upwelling. Temperature-Salinity properties of water masses in the canyon suggest active mixing between shelf and slope water masses near the canyon head. These results point to the importance of wind, double diffusion, and canyon topography on shelf-slope exchange in the MAB.

  13. Lake sedimentological and plant ecological development across the Early Danian hyperthermal, Boltysh Impact Crater, Ukraine

    NASA Astrophysics Data System (ADS)

    Ebinghaus, Alena; Jolley, David; Andrews, Steven; Kemp, David

    2017-04-01

    Past hyperthermals and associated negative carbon isotope excursions (CIEs) are inferred to have had significant impact on marine environments; however the formation and changes of terrestrial ecosystems across hyperthermals are less well constrained due to the lack of complete and high-resolution data. The Boltysh impact crater, Ukraine, which formed at the Cretaceous/Palaeogene (K/Pg) boundary at the northern margin of the Tethys Ocean, contains a >400 m thick unique and detailed lacustrine rock record of the Early Danian Dan-C2 hyperthermal. Based on a borehole (hole 42/11) drilled in the central part of the crater, we use a combination of sedimentological, palynological and carbon isotope data to 1) characterise and reconstruct lake formation and associated plant ecosystems, and 2) to assess lake sedimentological and ecological response to climatic variabilities during warming. Based on detailed facies analysis, 3 major gradual stages of lake formation are identified, indicating a strong relationship to carbon isotope shifts and associated climatic trends. Initial pre-excursion sedimentation was controlled by crater morphology and crater rim erosion transporting high amount of sediment into a shallow fresh water lake. During the negative excursion, sediment supply was increasingly characterised by inflow-evaporation ratio variabilities which affected seasonal stratification patterns and longer-term lake levels. An inferred increase in atmospheric pCO2 during the CIE, together with increasing mean annual temperatures, was likely responsible for periodic increases in bioproductivity. Palynological analyses demonstrate a gradual shift from mesic humid dominated vegetation to winterwet savannah-type vegetation at this stage, associated with an increase in mean annual temperatures and decrease in moisture availability. The positive excursion (recovery) and post-excursion stage is characterised by increased abundance of temperate mesic humid taxa. This cooling trend is associated with a gradual increase in sediment supply and return to fresh water conditions, reflecting increased drainage of the crater environment following the hyperthermal. Subordinate 21ky precession-paced moisture availability oscillations (MAOs) associated with rapid regime shifts from wet mesic humid to drier savannah biomes correspond to fluctuations in lake facies and lake levels during the negative excursion and suggest that a combination of climate and vegetation cover largely controlled clastic sediment supply at this stage. Smaller scaled regular variations in lamination style during each wet phase of the MAOs suggest a sub-orbital variability in weather conditions, sediment supply and lake stratification on probably annual to subannual scale and further implies changing magnitudes in seasonality. Gradual facies changes prior to CIE inception together with lamination variability suggests that the Dan-C2 event did not initiate large-scale sedimentological changes, but amplified and promoted sedimentary response to orbital controlled climate change.

  14. Bladder outlet obstruction treated with transurethral ultrasonic aspiration

    NASA Astrophysics Data System (ADS)

    Malloy, Terrence R.

    1991-07-01

    Fifty-nine males with bladder outlet obstruction were treated with transurethral ultrasonic aspiration of the prostate. Utilizing a 26.5 French urethral sheath, surgery was accomplished with a 10 French, 0-700 micron vibration level ultrasonic tip with an excursion rate of 39 kHz. Complete removal of the adenoma was accomplished, followed by transurethral electrocautery biopsies of both lateral lobes to compare pathologic specimens. One-year follow-up revealed satisfactory voiding patterns in 57 of 59 men (96%). Two men developed bladder neck contractures. Pathologic comparisons showed 100% correlation between aspirated and TUR specimens (56 BPH, 3 adeno-carcinoma). Forty-sevel men were active sexually preoperatively (6 with inflatable penile prostheses). Post ultrasonic aspiration, 46 men had erectile function similar to preoperative levels with one patient suffering erectile dysfunction. Forty men (85%) had antegrade ejaculation while 7 (15%) experienced retrograde or retarded ejaculation. No patients were incontinent.

  15. Swallowing Mechanics Associated With Artificial Airways, Bolus Properties, and Penetration-Aspiration Status in Trauma Patients.

    PubMed

    Dietsch, Angela M; Rowley, Christopher B; Solomon, Nancy Pearl; Pearson, William G

    2017-09-18

    Artificial airway procedures such as intubation and tracheotomy are common in the treatment of traumatic injuries, and bolus modifications may be implemented to help manage swallowing disorders. This study assessed artificial airway status, bolus properties (volume and viscosity), and the occurrence of laryngeal penetration and/or aspiration in relation to mechanical features of swallowing. Coordinates of anatomical landmarks were extracted at minimum and maximum hyolaryngeal excursion from 228 videofluoroscopic swallowing studies representing 69 traumatically injured U.S. military service members with dysphagia. Morphometric canonical variate and regression analyses examined associations between swallowing mechanics and bolus properties based on artificial airway and penetration-aspiration status. Significant differences in swallowing mechanics were detected between extubated versus tracheotomized (D = 1.32, p < .0001), extubated versus decannulated (D = 1.74, p < .0001), and decannulated versus tracheotomized (D = 1.24, p < .0001) groups per post hoc discriminant function analysis. Tracheotomy-in-situ and decannulated subgroups exhibited increased head/neck extension and posterior relocation of the larynx. Swallowing mechanics associated with (a) penetration-aspiration status and (b) bolus properties were moderately related for extubated and decannulated subgroups, but not the tracheotomized subgroup, per morphometric regression analysis. Specific differences in swallowing mechanics associated with artificial airway status and certain bolus properties may guide therapeutic intervention in trauma-based dysphagia.

  16. Relationship between selected measures of strength and hip and knee excursion during unilateral and bilateral landings in women.

    PubMed

    McCurdy, Kevin; Walker, John; Armstrong, Rusty; Langford, George

    2014-09-01

    The purpose of this study was to compare the relationship between several measures of single-joint, isometric, eccentric, and squat strength and unilateral and bilateral landing mechanics at the hip and knee in women. Twenty six healthy female subjects with previous athletic experience (height, 165.1 ± 7.01 cm; mass, 60.91 ± 7.14 kg; age, 20.9 ± 1.62 years) participated in this study. Hip and knee mechanics were measured using the MotionMonitor capture system (Innovative Sports Training, Inc.) with 3-dimensional electromagnetic sensors during bilateral (60 cm) and unilateral drop jumps (30 cm). On a separate day, isometric hip extension, external rotation, and abduction strength (lbs) were measured using a handheld dynamometer (Hoggan Health Industries, Inc.). Eccentric and isometric knee strength were measured on the Biodex IV Isokinetic Dynamometer (Biodex Medical Systems, Inc.). Free weight was used to measure the bilateral squat and a modified single-leg squat. The strongest correlations were found between squat strength and knee valgus (-0.77 ≤ r ≤ -0.83) and hip adduction (-0.5 ≤ r ≤ -0.65). After controlling for squat strength, hip external rotation strength and unilateral knee valgus (-0.41), hip abduction strength and bilateral knee valgus (-0.43), and knee flexion strength and bilateral hip adduction (-0.57) remained significant. Eccentric knee flexion strength and unilateral knee internal rotation was the only significant correlation for eccentric strength (-0.40). Squat strength seems to be the best predictor of knee valgus and was consistently related to hip adduction. Isometric and eccentric measures demonstrated few significant correlations with hip and knee excursion while demonstrating a low-to-moderate relationship. Hip and knee flexion and rotation do not seem to be related to strength. Squat strength should receive consideration during risk assessment for noncontact knee injury.

  17. Statistical signal analysis of the Phanerozoic ð13C curve: implications for Earth system evolution

    NASA Astrophysics Data System (ADS)

    Bachan, A.; Kump, L. R.; Payne, J.; Saltzman, M.; Thomas, E.

    2014-12-01

    In recent years, vast amounts of carbon isotopic data have been collected allowing the construction of the Phanerozoic δ13C curve in unprecedented detail. Our dataset comprises 8143 points spanning the last 541 m.y., with a mean spacing of 66 k.y. The average δ13C of Phanerozoic carbonate is 1 ‰ ± 2 ‰, in accordance with the canonical values measured in the past. However, the record also shows numerous, highly resolved, large (± 6 ‰) excursions whose magnitude declines through time, especially going into the late Mesozoic and Cenozoic. When the magnitude - distribution of the excursions is tabulated we find that it follows a power law: plotting the min-max differences vs. number of bins in which a particular value occurs reveals that the data fall on a semilogarithmic line with a slope of -0.23 and R2 = 0.99. The result is insensitive to outliers: smoothing the data with lowess, spline, Savitzky-Golay, and Butterworth filters yields similar results. The continuity from small variation to large perturbations, both positive and negative, suggests that, despite the numerous proposed causes for individual carbon isotopic evens, there is likely an underlying mechanism which governs the magnitude of δ13C response to perturbations. We suggest that a mechanism acting to amplify carbon cycle perturbations is the key to explaining the power-law distribution, and identify the anoxia-productivity feedback as the most likely candidate. Establishment of sulfidic conditions is accompanied by increased release of phosphate to the water column, which allows for further productivity, and thus acts as a destabilizing, positive, feedback. This feedback would act to increase carbon cycle swings irrespective of their proximal trigger. The decline in frequency of anoxic-sulfidic bottom waters in the world's oceans, and potential disappearance in the Late Mesozoic-Cenozoic, may account for a reduction in the Earth system's gain and increase in its resilience.

  18. Consistency of a lumbar movement pattern across functional activities in people with low back pain.

    PubMed

    Marich, Andrej V; Hwang, Ching-Ting; Salsich, Gretchen B; Lang, Catherine E; Van Dillen, Linda R

    2017-05-01

    Limitation in function is a primary reason people with low back pain seek medical treatment. Specific lumbar movement patterns, repeated throughout the day, have been proposed to contribute to the development and course of low back pain. Varying the demands of a functional activity test may provide some insight into whether people display consistent lumbar movement patterns during functional activities. Our purpose was to examine the consistency of the lumbar movement pattern during variations of a functional activity test in people with low back pain and back-healthy people. 16 back-healthy adults and 32 people with low back pain participated. Low back pain participants were classified based on the level of self-reported functional limitations. Participants performed 5 different conditions of a functional activity test. Lumbar excursion in the early phase of movement was examined. The association between functional limitations and early phase lumbar excursion for each test condition was examined. People with low back pain and high levels of functional limitation demonstrated a consistent pattern of greater early phase lumbar excursion across test conditions (p<0.05). For each test condition, the amount of early phase lumbar excursion was associated with functional limitation (r=0.28-0.62). Our research provides preliminary evidence that people with low back pain adopt consistent movement patterns during the performance of functional activities. Our findings indicate that the lumbar spine consistently moves more readily into its available range in people with low back pain and high levels of functional limitation. How the lumbar spine moves during a functional activity may contribute to functional limitations. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Chemostratigraphy of the Gohan Formation in the eastern central Korea : implications for the Capitanian environmental change

    NASA Astrophysics Data System (ADS)

    Kwon, Hyosang; Lee, Yong Il; Lim, Hyoun Soo

    2017-04-01

    The Gohan Formation in the Pyeongan Supergroup in central eastern Korea was deposited in a marginal marine to terrestrial setting in the Capitanian. It is 450 m thick and comprises alternation of gray-greenish medium-grained sandstone and mudrock. A detailed carbon isotope profile along with some paleoenvironmental proxies are presented for the Gohan Formation at Danyang site. CN ratios of organic matters reveal the presence of both vascular and non vascular plants. Excursion of carbon isotope ratios represents disturbance of carbon cycle. Carbon isotope values indicated a 3‰ negative excursion in the lower part of the studied section. This can be interpreted carbon cycle disturbance from the Capitanian extinction event. Mercury concentration is a proxy of volcanic activity. The horizon of a mercury peak near the bottom of the section is consistent with that of negative carbon isotope excursion and the coincidence between negative carbon isotope excursion and high mercury concentration may represent the influence from Emeishan volcanism, which has been regarded as a possible cause of the Capitanian extiction. Two more mercury peaks are noted in the upper part of the section but they are not related to carbon cycle disturbance which suggests effect of local volcanic eruptions as supported by the presence of volcanic rock fragments in coarse-grained sediment. Trace metal redox proxies indicate that the depositional basin was ventillated. TOC values tend to increase when the concentration of redox elements rise. However, the TOC and trace metal redox proxies trends are observed to behave independently of changes in carbon isotope and mercury concentrations suggesting transitions in local paleoenvironmental conditions.

  20. The effect of different unstable footwear constructions on centre of pressure motion during standing.

    PubMed

    Plom, W; Strike, S C; Taylor, M J D

    2014-06-01

    The aim of this study was to test the effect different unstable footwear constructions have on centre of pressure motion when standing. Sixteen young female volunteers were tested in five conditions, three unstable footwear (Reebok Easy-Tone, FitFlop and Skechers Shape-Ups), a standard shoe and barefoot in a randomised order. Double and single leg balance on a force plate was assessed via centre of pressure excursions and displacements in each condition. For double leg and single leg standing centre of pressure excursions in the anterior-posterior direction were significantly increased wearing Skechers Shape-Ups compared to barefoot and the standard shoe. For the Reebok Easy Tone during single leg standing excursions in the anterior-posterior direction were significantly greater compared to the barefoot condition. Cumulative displacement of the centre of pressure in medial-lateral direction increased significantly during single leg standing when wearing Skechers Shape-Ups compared to barefoot and standard shoe as well as for Reebok Easy Tone vs. barefoot. It would appear from these quiet standing results that the manner of the construction of instability shoes effects the CoP movement which is associated with induced instability. Greater CoP excursion occurred in the A-P direction while the cumulative displacements were greater in the M-L direction for those shoes with the rounded sole and soft foam and those with airpods. The shoe construction with altered density foam did not induce any change in the CoP movement, during quite standing, which tends to suggest that it is not effective at inducing balance. Not all instability shoes are effective in altering the overall instability of the wearer. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Sonographic assessment of changes in diaphragmatic kinetics induced by inspiratory resistive loading.

    PubMed

    Soilemezi, Eleni; Tsagourias, Matthew; Talias, Michael A; Soteriades, Elpidoforos S; Makrakis, Vasilios; Zakynthinos, Epaminondas; Matamis, Dimitrios

    2013-04-01

    Diaphragmatic breathing patterns under resistive loading remain poorly documented. To our knowledge, this is the first study assessing diaphragmatic motion under conditions of inspiratory resistive loading with the use of sonography. We assessed diaphragmatic motion during inspiratory resistive loading in 40 healthy volunteers using M-mode sonography. In phase I of the study, sonography was performed during normal quiet breathing without respiratory loading. In phase II, sonography was performed after application of a nose clip and connection of the subjects to a pneumotachograph through a mouth piece. In phase III, the participants were assessed while subjected to inspiratory resistive loading of 50 cm H(2)O/L/s. Compared with baseline, the application of a mouth piece and nose clip induced a significant increase in diaphragmatic excursion (from 1.7 to 2.3 cm, P < 0.001) and a decrease in respiratory rate (from 13.4 to 12.2, P < 0.01). Inspiratory resistive loading induced a further decrease in respiratory rate (from 12.2 to 8.0, P < 0.01) and a decrease in diaphragmatic velocity contraction (from 1.2 to 0.8 cm/s, P < 0.01), and also an increase in tidal volume (from 795 to 904 mL, P < 0.01); diaphragmatic excursion, however, did not change significantly. Inspiratory resistive loading induced significant changes in diaphragmatic contraction pattern, which mainly consisted of decreased velocity of diaphragmatic displacement with no change in diaphragmatic excursion. Tidal volume, increased significantly; the increase in tidal volume, along with the unchanged diaphragmatic excursion, provides sonographic evidence of increased recruitment of extradiaphragmatic muscles under inspiratory resistive loading. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  2. Impact of incretin on early-phase insulin secretion and glucose excursion.

    PubMed

    Shen, Jie; Chen, Zhi; Chen, Chaofeng; Zhu, Xiao; Han, Yajuan

    2013-10-01

    This study investigated the impact of incretin on early-phase insulin secretion and glucose excursion. The normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes mellitus (T2DM) groups included 16, 8, and 19 subjects, respectively. Subjects underwent continuous glucose monitoring for 3 days, followed by an oral glucose tolerance test. Plasma glucose, insulin, glucagon, total glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide-l (GLP-1) levels were measured at 30-min increments for 2 h after glucose intake. Differences with P < 0.05 were considered statistically significant. The area under the curve (AUC) of total GIP (120-min GIP-AUC) of the T2DM group was significantly lower than those of the NGT and IGT groups. The 120-min GLP-1-AUC of the NGT group was significantly larger than those of the T2DM and IGT groups. The early-phase insulin secretion index (ΔI30/ΔG30) of the T2DM group was significantly lower than those of the NGT and IGT groups. Mean amplitudes of glycemic excursions (MAGEs) went in the order of NGT < IGT < T2DM (P < 0.01, IGT vs. NGT; P < 0.001, T2DM vs. IGT). The 120-min GIP-AUC was negatively correlated with MAGE (r = -0.464), but uncorrelated with ΔI30/ΔG30. The 120-min GLP-1-AUC was positively correlated with ΔI30/ΔG30 (r = 0.580), but negatively correlated with MAGE (r = -0.606). Incretin may ameliorate glucose excursions, and GLP-1 may exert them by promoting early-phase insulin secretion. No correlation was observed between GIP secretion and early-phase insulin secretion.

  3. Additive effects of acidification and mineralogy on calcium isotopes in Triassic/Jurassic boundary limestones

    DOE PAGES

    Jost, Adam B.; Bachan, Aviv; van de Schootbrugge, Bas; ...

    2016-12-29

    The end-Triassic mass extinction coincided with a negative δ 13 C excursion, consistent with release of 13C-depleted CO 2 from the Central Atlantic Magmatic Province. However, the amount of carbon released and its effects on ocean chemistry are poorly constrained. The co upled nature of the carbon and calcium cycles allows calcium isotopes to be used for constraining carbon cycle dynamics and vice versa. We present a high-resolution calcium isotope (δ 44/40 Ca) record from 100 m of marine limestone spanning the Triassic/Jurassic boundary in two stratigraphic sections from northern Italy. Immediately above the extinction horizon and the associated negativemore » excursion in δ 13 C, δ 44/40 Ca decreases by ca. 0.8‰ in 20 m of section and then recovers to preexcursion values. Coupled numerical models of the geological carbon and calcium cycles demonstrate that this δ 44/40 Ca excursion is too large to be explained by changes to seawater δ 44/40 Ca alone, regardless of CO 2 injection volume and duration. Less than 20% of the δ 44/40 Ca excursion can be attributed to acidification. The remaining 80% likely reflects a higher proportion of aragonite in the original sediment, based largely on high concentrations of Sr in the samples. Our study demonstrates that coupled models of the carbon and calcium cycles have the potential to help distinguish contributions of primary seawater isotopic changes from local or diagenetic effects on the δ 44/40 Ca of carbonate sediments. Finally, differentiating between these effects is critical for constraining the impact of ocean acidification during the end-Triassic mass extinction, as well as for interpreting other environmental events in the geologic past.« less

  4. An Ecological Tipping Point Defined by Shallow Marine Foraminifera in the latest Paleocene

    NASA Astrophysics Data System (ADS)

    Robinson, M. M.; Spivey, W.

    2016-12-01

    The Paleocene-Eocene Thermal Maximum (PETM) is recognized in marine sediments by a carbonate dissolution zone, the extinction or turnover of benthic taxa, and a radiation of planktic excursion taxa, all accompanied by a rapid-onset, negative carbon isotope excursion (CIE). We present foraminiferal evidence from shallow marine sediments in southeastern Maryland, USA, where accumulation rates are high, for a minor ocean acidification event in the latest Paleocene that coincides with a relatively small (-2‰) CIE. This pre-onset excursion (POE) precedes the larger (-4‰) PETM CIE onset and dissolution event. During the POE, the benthic assemblage is reconfigured toward agglutinated species in order to adapt to increased acidity, and the planktic assemblage begins to speciate due to perturbed mixed layer conditions. The benthic assemblage returns to normal, without interruption, as the POE recovers, but planktic excursion taxa continue to appear in very low numbers. This is contrasted to the major ocean acidification event associated with the PETM CIE onset that results in a zone of complete dissolution followed by distinctive benthic and planktic foraminiferal assemblages. Our microfossil evidence documents a biotic response to bottom water and mixed layer perturbations that illustrates how coastal ecosystems react to both moderate and severe ocean acidification events, bracketing the ecological tipping point of shallow marine ecosystems. The POE, roughly half the magnitude of the CIE onset, provides insight into the nature of the initial effects of climate perturbation as well as an example of one that is fully recoverable. It is here that research aimed to better understand the long-term effects and reversibility of modern deteriorating oceanic conditions should focus. This study provides an initial metric by which to measure modern ecosystem disturbances and will help to define the tipping point for the shallow marine environment.

  5. Finite element comparison of human and Hybrid III responses in a frontal impact.

    PubMed

    Danelson, Kerry A; Golman, Adam J; Kemper, Andrew R; Gayzik, F Scott; Clay Gabler, H; Duma, Stefan M; Stitzel, Joel D

    2015-12-01

    The improvement of finite element (FE) Human Body Models (HBMs) has made them valuable tools for investigating restraint interactions compared to anthropomorphic test devices (ATDs). The objective of this study was to evaluate the effect of various combinations of safety restraint systems on the sensitivity of thoracic injury criteria using matched ATD and Human Body Model (HBM) simulations at two crash severities. A total of seven (7) variables were investigated: 3-point belt with two (2) load limits, frontal airbag, knee bolster airbag, a buckle pretensioner, and two (2) delta-v's - 40kph and 50kph. Twenty four (24) simulations were conducted for the Hybrid III ATD FE model and repeated with a validated HBM for 48 total simulations. Metrics tested in these conditions included sternum deflection, chest acceleration, chest excursion, Viscous Criteria (V*C) criteria, pelvis acceleration, pelvis excursion, and femur forces. Additionally, chest band deflection and rib strain distribution were measured in the HBM for additional restraint condition discrimination. The addition of a frontal airbag had the largest effect on the occupant chest metrics with an increase in chest compression and acceleration but a decrease in excursion. While the THUMS and Hybrid III occupants demonstrated the same trend in the chest compression measurements, there were conflicting results in the V*C, acceleration, and displacement metrics. Similarly, the knee bolster airbag had the largest effect on the pelvis with a decrease in acceleration and excursion. With a knee bolster airbag the simulated occupants gave conflicting results, the THUMS had a decrease in femur force and the ATD had an increase. Preferential use of dummies or HBM's is not debated; however, this study highlights the ability of HBM metrics to capture additional chest response metrics. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Carbon associated nitrate (CAN) in the Ediacaran Johnnie Formation, Death Valley, California and links to the Shuram negative carbon isotope excursion

    NASA Astrophysics Data System (ADS)

    Dilles, Z. Y. G.; Prokopenko, M. G.; Bergmann, K.; Loyd, S. J.; Corsetti, F. A.; Berelson, W.; Gaines, R. R.

    2014-12-01

    Nitrogen, a major nutrient of marine primary production whose many redox states are linked through biological processes to O2, may afford better understanding of changes in post-Great Oxidation Event (GOE) environmental redox conditions. Using a novel approach to quantify nitrate content in carbonates, we identified a trend of CAN increase in the late-Proterozoic, including several distinct peaks within a carbonate succession of the Sonora province, Mexico, deposited ~630-500 Ma. The goal of the current study was to investigate CAN variability in the context of the global "Shuram" event, a large negative δ13C excursion expressed in Rainstorm member carbonates of the Johnnie Formation in Death Valley, CA. The lower Rainstorm Member "Johnnie Oolite", a time-transgressive, regionally extensive, shallow dolomitic oolite, was sampled. CAN concentrations ranged from 7.31 to 127.36 nmol/g, with higher values measured toward the base of the bed. This trend held at each sampled locality, along with a tendency towards decreasing CAN with larger magnitude negative δ13C excursions. Modern analog ooids formed in low-latitude marine environments lack CAN, consistent with their formation in low-nitrate waters of the euphotic zone characteristic of the modern ocean nitrogen cycling. In contrast, maximum values within the Johnnie oolite exceed by a factor of five to seven CAN measured in carbonates deposited below the main nitracline in the modern ocean, implying high nitrate content within shallow depositional environments. Johnnie oolite data, broadly consistent with the Sonora sequence findings, may indicate large perturbations in the Ediacaran nitrogen cycle immediately preceding the negative δ13C excursion. The implication of these findings for possible changes in the Ediacaran nitrogen, oxygen and carbon biogeochemical cycling will be further discussed.

  7. Additive effects of acidification and mineralogy on calcium isotopes in Triassic/Jurassic boundary limestones

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jost, Adam B.; Bachan, Aviv; van de Schootbrugge, Bas

    The end-Triassic mass extinction coincided with a negative δ 13 C excursion, consistent with release of 13C-depleted CO 2 from the Central Atlantic Magmatic Province. However, the amount of carbon released and its effects on ocean chemistry are poorly constrained. The co upled nature of the carbon and calcium cycles allows calcium isotopes to be used for constraining carbon cycle dynamics and vice versa. We present a high-resolution calcium isotope (δ 44/40 Ca) record from 100 m of marine limestone spanning the Triassic/Jurassic boundary in two stratigraphic sections from northern Italy. Immediately above the extinction horizon and the associated negativemore » excursion in δ 13 C, δ 44/40 Ca decreases by ca. 0.8‰ in 20 m of section and then recovers to preexcursion values. Coupled numerical models of the geological carbon and calcium cycles demonstrate that this δ 44/40 Ca excursion is too large to be explained by changes to seawater δ 44/40 Ca alone, regardless of CO 2 injection volume and duration. Less than 20% of the δ 44/40 Ca excursion can be attributed to acidification. The remaining 80% likely reflects a higher proportion of aragonite in the original sediment, based largely on high concentrations of Sr in the samples. Our study demonstrates that coupled models of the carbon and calcium cycles have the potential to help distinguish contributions of primary seawater isotopic changes from local or diagenetic effects on the δ 44/40 Ca of carbonate sediments. Finally, differentiating between these effects is critical for constraining the impact of ocean acidification during the end-Triassic mass extinction, as well as for interpreting other environmental events in the geologic past.« less

  8. The Mediolateral Excursion of the Meniscal Bearing during Flexion and Extension of the Knee after Medial Mobile-Bearing Unicompartmental Knee Arthroplasty.

    PubMed

    Lee, Seung-Yup; Bae, Ji-Hoon; Suh, Dong-Won; Kim, Han-Ju; Lim, Hong-Chul

    2017-02-01

    This mediolateral excursion of the bearing during knee motion is supposed to be caused by external rotation of the tibia during knee extension. However, to our knowledge, there is no published clinical evidence supporting these hypotheses. The current study aimed to evaluate the mediolateral excursion of the bearing during flexion-extension motion of the knee after medial unicompartmental knee arthroplasty (UKA). In 52 knees, varus/valgus (F-VarVal) or rotational position (F-Rot) of the femoral component and relative location of the bearing were measured with the standing anteroposterior and modified axial view, respectively. We adopted the modified axial radiographs that are simple to assess the bearing position in the flexed knee. The modified axial view showed excellent inter- and intraobserver agreements. F-Rot in the modified axial view and CT showed a high agreement in terms of validity (r = 0.98; p  < 0.0001). On average, the bearing showed more medial position in extension than flexion of the knee. No correlation was found between the femoral component positions (F-VarVal and F-Rot) and mediolateral bearing excursion ( p  = 0.68 and 0.80, respectively). In conclusion, coronal location of bearing according to flexion-extension of the knee is not influenced by the coronal and axial alignment of the femoral component. With simple radiographic method, more medial position of the bearing according to flexion-extension of the knee. Our method could be used to assess axial rotation of the femoral component and spin-out phenomenon of the bearing following the medial UKA. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  9. Reduced Bearing Excursion After Mobile-Bearing Unicompartmental Knee Arthroplasty is Associated With Poor Functional Outcomes.

    PubMed

    Wahal, Naman; Gaba, Sahil; Malhotra, Rajesh; Kumar, Vijay; Pegg, Elise C; Pandit, Hemant

    2018-02-01

    A small proportion of patients with mobile unicompartmental knee arthroplasty (UKA) report poor functional outcomes in spite of optimal component alignment on postoperative radiographs. The purpose of this study is to assess whether there is a correlation between functional outcome and knee kinematics. From a cohort of consecutive cases of 150 Oxford medial UKA, patients with fair/poor functional outcome at 1-year postsurgery (Oxford Knee Score [OKS] < 34, n = 15) were identified and matched for age, gender, preoperative clinical scores, and follow-up period with a cohort of patients with good/excellent outcome (OKS ≥ 34, n = 15). In vivo kinematic assessment was performed using step-up and deep knee bend exercises under fluoroscopic imaging. The fluoroscopic videos were analyzed using MATLAB software to measure the variation in time taken to complete the exercises, patellar tendon angle, and bearing position with knee flexion angle. Mean OKS in the fair/poor group was 29.9 and the mean OKS in the good/excellent group was 41.1. The tibial slope, time taken to complete the exercises, and patellar tendon angle trend over the flexion range were similar in both the groups; however, bearing position and the extent of bearing excursion differed significantly. The total bearing excursion in the OKS < 34 group was significantly smaller than the OKS ≥ 34 group (35%). Furthermore, on average, the bearing was positioned 1.7 mm more posterior on the tibia in the OKS < 34 group. This study provides evidence that abnormal knee kinematics, in particular bearing excursion and positioning, are associated with worse functional outcomes after mobile UKA. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Reliability and comparison of trunk and pelvis angles, arm distance and center of pressure in the seated functional reach test with and without foot support in children.

    PubMed

    Radtka, Sandra; Zayac, Jacqueline; Goldberg, Krystyna; Long, Michael; Ixanov, Rustem

    2017-03-01

    This study determined test-retest reliability of trunk and pelvis joint angles, arm distance and center of pressure (COP) excursion for the seated functional reach test (FRT) and compared these variables during the seated FRT with and without foot support. Fifteen typically developing children (age 9.3±4.1years) participated. Trunk and pelvis joint angles, arm distance, and COP excursion were collected on two days using three-dimensional motion analysis and a force plate while subjects reached maximally with and without foot support in the anterior, anterior/lateral, lateral, posterior/lateral directions. Age, weight, height, trunk and arm lengths were correlated (p<0.01) with maximum arm distance reached. Maximum arm distance, trunk and pelvis joint angles, and COP with and without foot support were not significant (p<0.05) for the two test periods. Excellent reliability (ICCs>0.75) was found for maximum arm distance reached in all four directions in the seated FRT with and without foot support. Most trunk and pelvis joint angles and COP excursions during maximum reach in all four directions showed excellent to fair reliability (ICCs>0.40-0.75). Reaching with foot support in all directions was significantly greater (p<0.05) than without foot support; however, most COP excursions and trunk and pelvic angles were not significantly different. Findings support the addition of anterior/lateral and posterior/lateral reaching directions in the seated FRT. Trunk and pelvis movement analysis is important to examine in the seated FRT to determine the specific movement strategies needed for maximum reaching without loss of balance. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. IODP Expedition 303 (North Atlantic): Excursions and Reversals in the Brunhes and Matuyama Chrons

    NASA Astrophysics Data System (ADS)

    Channell, J. E.; Mazaud, A.; Stoner, J. S.

    2005-12-01

    The primary objective of IODP Expedition 303 (Sept.-Nov., 2004) was to recover complete and continuous records of Pliocene-Quaternary millennial-scale environmental and geomagnetic variability, and place these records into high-resolution isotopic and magnetic stratigraphies (including relative paleointensity). Some of the Exp. 303 site locations (Orphan Knoll, Eirik and Gardar Drifts, and DSDP Site 609) have already been instrumental in developing marine records of suborbital climate variability for the last climate cycle, and the goal of Exp. 303 was to extend the records back through the Quaternary and into the Pliocene. High mean sedimentation rates (15-20 cm/ky) at sites located on Orphan Knoll (Site U1302/3), Eirik Drift (Sites U1305 and U1306) and Gardar Drift (Site U1304) have resulted in shipboard records of excursions and reversals in the Brunhes and Matuyama Chrons. Site U1308 (DSDP Site 609) has lower mean sedimentation rate (7.9 cm/kyr) and extends the record into the Gauss Chron to ~3.1 Ma. Initial u-channel magnetic data support the existence of a number of polarity excursions in the Matuyama Chron, but only a single polarity excursion (Iceland Basin Event) has so far been observed in the Brunhes Chron. The Matuyama-Brunhes (M-B) polarity reversal yields virtual geomagnetic polar (VGP) paths that are reminiscent of those recovered from the northern Gardar and Bjorn drifts during ODP Leg 162. VGP clusters in the South Atlantic and off NE Asia accompany a Pacific loop, in what appears to be a repetitive but complex pattern for the M-B transition recorded in 9 holes from three Exp. 303 North Atlantic sites.

  12. Strategies adopted by younger and older adults while operating a non-pedal tricycle.

    PubMed

    Calve, Tatiane; Russo Júnior, Douglas Vicente; Barela, Ana Maria Forti

    Exercises that could prevent gait impairment of older adults should be implemented in such a way that practitioners can keep motivation and adherence independent of older adults fitness levels. This study describes how younger and older adults use a non-pedal tricycle to transport their bodies along a pathway. Nine younger (24±4.9y) and nine older (66±4.0y) adults participated in this study. They moved along a straight pathway at a self-selected comfortable speed with reflective markers on their main lower limb landmarks. A computerized gait analysis system with infrared cameras was used to obtain kinematic data to calculate spatial-temporal parameters and lower limb angles. Overall, participants from both groups were able to perform the task moving at a similar mean speed, with similar stride length and ankle joint excursion. Older adults had higher cadence (mean difference of 17steps/min; 95% CI=0.99-1.15) and hip excursion (mean difference of 12°; 95% CI=28-33), longer stance duration (mean difference of 3.4%; 95% CI=56.2-59.5), and lower knee excursion (mean difference of 6°; 95% CI=47.9-53.8) than younger adults. Older adults were able to transport their body with a non-pedal tricycle with more hip and less knee excursion than younger adults. Professionals that work with the older population should look at and take into consideration the use of non-pedal tricycles in exercise protocols and investigate the long-term impacts. Copyright © 2017 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier Editora Ltda. All rights reserved.

  13. Serial Testing of Postural Control After Acute Lateral Ankle Sprain

    PubMed Central

    Buckley, W. E.; Denegar, Craig R.

    2001-01-01

    Objective: To identify subjects' changes in postural control during single-leg stance in the 4 weeks after acute lateral ankle sprain. Design and Setting: We used a 2 × 2 × 3 (side-by-plane-by-session) within-subjects design with repeated measures on all 3 factors. All tests were performed in a university laboratory. Subjects: Seventeen young adults (9 men, 8 women; age, 21.8 ± 5.9 years; mass, 74.9 ± 10.5 kg; height, 176.9 ± 7.1 cm) who had sustained unilateral acute mild or moderate lateral ankle sprains. Measurements: Measures of center-of-pressure excursion length, root mean square velocity of center-of-pressure excursions (VEL), and range of center-of-pressure excursions (RANGE) were calculated separately in the frontal and sagittal planes during 5-second trials of static single-leg stance. Results: We noted significant side-by-plane-by-session interactions for magnitude of center-of-pressure excursions in a given trial (PSL) (P = .004), VEL (P = .011), and RANGE (P = .009). Both PSL and VEL in the frontal plane were greater in the injured limbs compared with the uninjured limbs on day 1 and during week 2 but not during week 4, whereas sagittal-plane differences existed during all 3 testing sessions. Injured-limb, frontal-plane RANGE scores were greater than uninjured values at day 1 but not during weeks 2 or 4. No significant differences in sagittal-plane RANGE scores were seen. Conclusions: Postural control was significantly impaired in the injured limbs at day 1 and during week 2 after lateral ankle sprain but not during week 4. Consistent improvement in postural control measures on both injured and uninjured limbs was seen throughout the 4 weeks after ankle sprain. PMID:12937477

  14. Bithermal fatigue: A simplified alternative to thermomechanical fatigue

    NASA Technical Reports Server (NTRS)

    Verrilli, Michael J.

    1988-01-01

    A bithermal fatigue test technique was proposed as a simplified alternative to the thermomechanical fatigue test. Both the thermomechanical cycle and the bithermal technique can be used to study nonisothermal fatigue behavior. The difference between the two cycles is that in a conventional thermomechanical fatigue cycle the temperature is continuously varied concurrently with the applied mechanical strains, but in the bithermal fatigue cycle the specimen is held at zero load during the temperature excursions and all the loads are applied at the two extreme temperatures of the cycle. Experimentally, the bithermal fatigue test technique offers advantages such as ease in synchronizing the temperature and mechanical strain waveforms, in minimizing temperature gradients in the specimen gauge length, and in reducing and interpreting thermal fatigue such as the influence of alternate high and low temperatures on the cyclic stress-strain response characteristics, the effects of thermal state, and the possibility of introducing high- and low-temperature deformation mechanisms within the same cycle. The bithermal technique was used to study nonisothermal fatigue behavior of alloys such as single-crystal PWA 1480, single-crystal Rene N4, cast B1900+Hf, and wrought Haynes 188.

  15. Using Xbox kinect motion capture technology to improve clinical rehabilitation outcomes for balance and cardiovascular health in an individual with chronic TBI.

    PubMed

    Chanpimol, Shane; Seamon, Bryant; Hernandez, Haniel; Harris-Love, Michael; Blackman, Marc R

    2017-01-01

    Motion capture virtual reality-based rehabilitation has become more common. However, therapists face challenges to the implementation of virtual reality (VR) in clinical settings. Use of motion capture technology such as the Xbox Kinect may provide a useful rehabilitation tool for the treatment of postural instability and cardiovascular deconditioning in individuals with chronic severe traumatic brain injury (TBI). The primary purpose of this study was to evaluate the effects of a Kinect-based VR intervention using commercially available motion capture games on balance outcomes for an individual with chronic TBI. The secondary purpose was to assess the feasibility of this intervention for eliciting cardiovascular adaptations. A single system experimental design ( n = 1) was utilized, which included baseline, intervention, and retention phases. Repeated measures were used to evaluate the effects of an 8-week supervised exercise intervention using two Xbox One Kinect games. Balance was characterized using the dynamic gait index (DGI), functional reach test (FRT), and Limits of Stability (LOS) test on the NeuroCom Balance Master. The LOS assesses end-point excursion (EPE), maximal excursion (MXE), and directional control (DCL) during weight-shifting tasks. Cardiovascular and activity measures were characterized by heart rate at the end of exercise (HRe), total gameplay time (TAT), and time spent in a therapeutic heart rate (TTR) during the Kinect intervention. Chi-square and ANOVA testing were used to analyze the data. Dynamic balance, characterized by the DGI, increased during the intervention phase χ 2 (1, N = 12) = 12, p = .001. Static balance, characterized by the FRT showed no significant changes. The EPE increased during the intervention phase in the backward direction χ 2 (1, N = 12) = 5.6, p = .02, and notable improvements of DCL were demonstrated in all directions. HRe ( F (2,174) = 29.65, p = < .001) and time in a TTR ( F (2, 12) = 4.19, p = .04) decreased over the course of the intervention phase. Use of a supervised Kinect-based program that incorporated commercial games improved dynamic balance for an individual post severe TBI. Additionally, moderate cardiovascular activity was achieved through motion capture gaming. Further studies appear warranted to determine the potential therapeutic utility of commercial VR games in this patient population. Clinicaltrial.gov ID - NCT02889289.

  16. Space Operations Center, Shuttle Interaction Study. Volume 2: Appendices, Book 1 of 2

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The feasibility of shuttle orbiter docking to the Space Operations Center (SOC) is studied. The in-orbit relative motion of the free flying orbiter and SOC was simulated, accounting for the Orbiter RCS and digital autopilot (DAP) systems, orbital mechanics, center of gravity offset of the orbiter docking port, aero and gravity gradient effects, and other pertinent natural and man-made phenomena. Since there is no specified flight path and procedure for docking, terminal closure sensitivities were investigated. Orbiter approach direction, Orbiter approach attitude out of plane, DAP thruster compensation mode, final ballistic docking distance and time to dock, rate and excursion attitude deadbands, and selection of various thruster combinations (differing from nominal) for translational pulses are considered.

  17. Dynamic behavior of particles in spacecraft

    NASA Technical Reports Server (NTRS)

    Perrine, B. S.

    1981-01-01

    The behavior of particles relative to a spacecraft frame of reference was examined. Significant spatial excursions of particles in space can occur relative to the spacecraft frame of reference as a result of drag deceleration of the vehicle. These vehicle excursions tend to be large as time increases. Thus, if the particle is required to remain in a specified volume, constraints may be required. Thus, for example, in levitation experiments it may be extremely difficult to turn off the forces of constraint which keep the particles in a specified region. This means experiments which are sensitive to disturbances may be very difficult to perform if perturbation forces are required to be absent.

  18. Outbreaks of Gastroenteritis That Occurred during School Excursions in Korea Were Associated with Several Waterborne Strains of Norovirus

    PubMed Central

    Kim, Sung-Han; Cheon, Doo-Sung; Kim, Jin-Hyeun; Lee, Dong-Han; Jheong, Won-hwa; Heo, Young-Joo; Chung, Hyen-Mi; Jee, Youngmee; Lee, Joo-Shil

    2005-01-01

    In May 2004, 97 of 309 (31%) and 97 of 207 (47%) school students from geographically distant areas were affected by acute gastroenteritis during excursions to neighboring hotels. The two hotels were 300 m apart, on Jeju Island, South Korea. Several strains of norovirus, including both genogroup I and genogroup II viruses, were identified in stool samples from the students and food handlers and in groundwater from the hotels. Of these several strains of norovirus, the nucleotide sequences for one strain were identical for samples from the students, food handlers, and groundwater. PMID:16145153

  19. Mercury enrichment indicates volcanic triggering of Valanginian environmental change

    PubMed Central

    Charbonnier, Guillaume; Morales, Chloé; Duchamp-Alphonse, Stéphanie; Westermann, Stéphane; Adatte, Thierry; Föllmi, Karl B.

    2017-01-01

    The Valanginian stage (Early Cretaceous) includes an episode of significant environmental changes, which are well defined by a positive δ13C excursion. This globally recorded excursion indicates important perturbations in the carbon cycle, which has tentatively been associated with a pulse in volcanic activity and the formation of the Paraná-Etendeka large igneous province (LIP). Uncertainties in existing age models preclude, however, its positive identification as a trigger of Valanginian environmental changes. Here we report that in Valanginian sediments recovered from a drill core in Wąwał (Polish Basin, Poland), and from outcrops in the Breggia Gorge (Lombardian Basin, southern Switzerland), and Orpierre and Angles (Vocontian Basin, SE France), intervals at or near the onset of the positive δ13C excursion are significantly enriched in mercury (Hg). The persistence of the Hg anomaly in Hg/TOC, Hg/phyllosilicate, and Hg/Fe ratios shows that organic-matter scavenging and/or adsorbtion onto clay minerals or hydrous iron oxides only played a limited role. Volcanic outgassing was most probably the primary source of the Hg enrichments, which demonstrate that an important magmatic pulse triggered the Valanginian environmental perturbations. PMID:28106091

  20. Preliminary paleomagnetic results from the Coyote Creek Outdoor Classroom drill hole, Santa Clara Valley, California

    USGS Publications Warehouse

    Mankinen, Edward A.; Wentworth, Carl M.

    2003-01-01

    Paleomagnetic samples were obtained from cores taken during the drilling of a research well along Coyote Creek in San Jose, California, in order to use the geomagnetic field behavior recorded in those samples to provide age constraints for the sediment encountered. The well reached a depth of 308 meters and material apparently was deposited largely (entirely?) during the Brunhes Normal Polarity Chron, which lasted from 780 ka to the present time. Three episodes of anomalous magnetic inclinations were recorded in parts of the sedimentary sequence; the uppermost two we correlate to the Mono Lake (~30 ka) geomagnetic excursion and 6 cm lower, tentatively to the Laschamp (~45 ka) excursion. The lowermost anomalous interval occurs at 305 m and consists of less than 10 cm of fully reversed inclinations underlain by 1.5 m of normal polarity sediment. This lower anomalous interval may represent either the Big Lost excursion (~565 ka) or the polarity transition at the end of the Matuyama Reversed Polarity Chron (780 ka). The average rates of deposition for the Pleistocene section in this well, based on these two alternatives, are approximately 52 or 37 cm/kyr, respectively.

  1. Effect of eating vegetables before carbohydrates on glucose excursions in patients with type 2 diabetes

    PubMed Central

    Imai, Saeko; Fukui, Michiaki; Kajiyama, Shizuo

    2014-01-01

    The aim of this review was to evaluate whether eating vegetables before carbohydrates could reduce the postprandial glucose, insulin, and improve long-term glycemic control in Japanese patients with type 2 diabetes. We studied the effect of eating vegetables before carbohydrates on postprandial plasma glucose, insulin, and glycemic control for 2.5 y in patients with type 2 diabetes. The postprandial glucose and insulin levels decreased significantly when the patients ate vegetables before carbohydrates compared to the reverse regimen, and the improvement of glycemic control was observed for 2.5 y. We also compared the postprandial glucose and glucose fluctuations assessed by continuous glucose monitoring system for 72-h in patients with type 2 diabetes and subjects with normal glucose tolerance when subjects ate vegetables before carbohydrates and carbohydrates before vegetables in a randomized crossover design. The glycemic excursions and incremental glucose peak were significantly lower when the subjects ate vegetables before carbohydrates compared to the reverse regimen. This evidence supports the effectiveness of eating vegetables before carbohydrates on glucose excursions in the short-term and glycemic control in the long-term in patients with type 2 diabetes. PMID:24426184

  2. Effect of eating vegetables before carbohydrates on glucose excursions in patients with type 2 diabetes.

    PubMed

    Imai, Saeko; Fukui, Michiaki; Kajiyama, Shizuo

    2014-01-01

    The aim of this review was to evaluate whether eating vegetables before carbohydrates could reduce the postprandial glucose, insulin, and improve long-term glycemic control in Japanese patients with type 2 diabetes. We studied the effect of eating vegetables before carbohydrates on postprandial plasma glucose, insulin, and glycemic control for 2.5 y in patients with type 2 diabetes. The postprandial glucose and insulin levels decreased significantly when the patients ate vegetables before carbohydrates compared to the reverse regimen, and the improvement of glycemic control was observed for 2.5 y. We also compared the postprandial glucose and glucose fluctuations assessed by continuous glucose monitoring system for 72-h in patients with type 2 diabetes and subjects with normal glucose tolerance when subjects ate vegetables before carbohydrates and carbohydrates before vegetables in a randomized crossover design. The glycemic excursions and incremental glucose peak were significantly lower when the subjects ate vegetables before carbohydrates compared to the reverse regimen. This evidence supports the effectiveness of eating vegetables before carbohydrates on glucose excursions in the short-term and glycemic control in the long-term in patients with type 2 diabetes.

  3. Advantage of bimodal fitting in prosody perception for children using a cochlear implant and a hearing aid.

    PubMed

    Straatman, L V; Rietveld, A C M; Beijen, J; Mylanus, E A M; Mens, L H M

    2010-10-01

    Cochlear implants are largely unable to encode voice pitch information, which hampers the perception of some prosodic cues, such as intonation. This study investigated whether children with a cochlear implant in one ear were better able to detect differences in intonation when a hearing aid was added in the other ear ("bimodal fitting"). Fourteen children with normal hearing and 19 children with bimodal fitting participated in two experiments. The first experiment assessed the just noticeable difference in F0, by presenting listeners with a naturally produced bisyllabic utterance with an artificially manipulated pitch accent. The second experiment assessed the ability to distinguish between questions and affirmations in Dutch words, again by using artificial manipulation of F0. For the implanted group, performance significantly improved in each experiment when the hearing aid was added. However, even with a hearing aid, the implanted group required exaggerated F0 excursions to perceive a pitch accent and to identify a question. These exaggerated excursions are close to the maximum excursions typically used by Dutch speakers. Nevertheless, the results of this study showed that compared to the implant only condition, bimodal fitting improved the perception of intonation.

  4. Cinerama sickness and postural instability.

    PubMed

    Bos, Jelte E; Ledegang, Wietse D; Lubeck, Astrid J A; Stins, John F

    2013-01-01

    Motion sickness symptoms and increased postural instability induced by motion pictures have been reported in a laboratory, but not in a real cinema. We, therefore, carried out an observational study recording sickness severity and postural instability in 19 subjects before, immediately and 45 min after watching a 1 h 3D aviation documentary in a cinema. Sickness was significantly larger right after the movie than before, and in a lesser extent still so after 45 min. The average standard deviation of the lateral centre of pressure excursions was significantly larger only right afterwards. When low-pass filtered at 0.1 Hz, lateral and for-aft excursions were both significantly larger right after the movie, while for-aft excursions then remained larger even after 45 min. Speculating on previous findings, we predict more sickness and postural instability in 3D than in 2D movies, also suggesting a possible, but yet unknown risk for work-related activities and vehicle operation. Watching motion pictures may be sickening and posturally destabilising, but effects in a cinema are unknown. We, therefore, carried out an observational study showing that sickness then is mainly an issue during the exposure while postural instability is an issue afterwards.

  5. Preliminary Earth System Modeling (cGENIE) of Paired Organic and Inorganic Carbon Isotope Records to Investigate Carbon Cycle Behavior During the Triassic-Jurassic Transition

    NASA Astrophysics Data System (ADS)

    Yager, J. A.; Stellmann, J. L.; West, A. J.; Corsetti, F. A.; Berelson, W.; Bottjer, D. J.; Rosas, S.

    2016-12-01

    The stable C isotope composition of marine carbonate and organic C yields information regarding major changes in global carbon cycling over geologic time. Excursions from baseline C isotope compositions during the Late Triassic and early Jurassic coincide with the end-Triassic mass extinction. Much remains to be understood about the global extent of these excursions, and about their causes. Here, we use observations from a record from Northern Peru (Levanto) to generate hypotheses concerning C cycle changes, focusing on comparison to other sections spanning the Triassic-Jurassic boundary. Our observations include a decoupling between organic and inorganic C isotopes in some records, broad similarities in the pattern of excursions between sections, and a potential offset between the major ocean basins (Tethys and Panthalassa) in both inorganic and organic C isotope records. We are currently adapting a spatially resolved Earth System Model (cGENIE) for this time period with the goal of using this model to explore possible mechanistic causes of these observations, aiming to tie the C isotope records to changes in global carbon cycle dynamics at the time.

  6. A virtual, interactive and dynamic excursion in Google Earth on soil management and conservation (AgroGeovid)

    NASA Astrophysics Data System (ADS)

    Vanwalleghem, Tom; Giráldez, Juan Vicente

    2013-04-01

    Many courses on natural resources require hands-on practical knowledge and experience that students traditionally could only acquire by expensive and time-consuming field excursions. New technologies and social media however provide an interesting alternative to train students and help them improve their practical knowledge. AgroGeovid is a virtual excursion, based on Google Earth, Youtube, Facebook and Twitter that is aimed at agricultural engineering students, but equally useful for any student interested in soil management and conservation, e.g. geography, geology and environmental resources. Agrogeovid provides the framework for teachers and students to upload geotagged photos, comments and discussions. After the initial startup phase, where the teacher uploaded material on e.g. soil erosion phenomena, soil conservation structures and different soil management strategies under different agronomic systems, students contributed with their own material gathered throughout the academic year. All students decided to contribute via Facebook, in stead of Twitter, which was not known to most of them. The final result was a visual and dynamic tool which students could use to train and perfect skills adopted in the classroom using case-studies and examples from their immediate environment.

  7. Transplanckian censorship and global cosmic strings

    NASA Astrophysics Data System (ADS)

    Dolan, Matthew J.; Draper, Patrick; Kozaczuk, Jonathan; Patel, Hiren

    2017-04-01

    Large field excursions are required in a number of axion models of inflation. These models also possess global cosmic strings, around which the axion follows a path mirroring the inflationary trajectory. Cosmic strings are thus an interesting theoretical laboratory for the study of transplanckian field excursions. We describe connections be-tween various effective field theory models of axion monodromy and study the classical spacetimes around their supercritical cosmic strings. For small decay constants f < M p and large winding numbers n > M p /f , the EFT is under control and the string cores undergo topological inflation, which may be either of exponential or power-law type. We show that the exterior spacetime is nonsingular and equivalent to a decompactifying cigar geometry, with the radion rolling in a potential generated by axion flux. Signals are able to circumnavigate infinite straight strings in finite but exponentially long time, t ˜ e Δ a/ M p . For finite loops of supercritical string in asymptotically flat space, we argue that if topological inflation occurs, then topological censorship implies transplanckian censorship, or that external observers are forbidden from threading the loop and observing the full excursion of the axion.

  8. Stereometric Analysis Of Static Equilibrium In CNS Disorders

    NASA Astrophysics Data System (ADS)

    Sheffer, D. B.; Lehmkuhl, D. L.; Herron, R. E.

    1980-07-01

    A primary aim in the physical rehabilitation of individuals with severe head or spinal injuries resulting in hemiparesis, tetraparesis or paraparesis, is the restoration of the functional motor abilities controlling involved muscle groups. The regaining of trunk postural stability provides a valuable antecedent in the recovery of use of the arms and legs. Accurate objective infor-mation must be provided to the therapist for assessment of treatment regimes. At present, few objective practical methods are available to furnish this evaluative information. Therefore the purpose of this study was to investigate the use of a biostereometric range of motion sensor for recording and quantifying trunk static equilibrium in individuals ungergoing therapy for head trauma. The sensor located the relative position of the C-7 vertebrae of the patient in space using continual monitoring of spherical coordinates. Results of the test protocol included : plots of the movement of the trunk excursions, determination of the maximum area of excursion and a trunk sway index (the relationship of the maximum area, the total excursion distance and a time factor). Further results demonstrated that the biostereometric sensor yielded quantitative documentation of improvement in a patient undergoing therapy.

  9. Short Magma Residence Times at Mt. Rainier and the Probable Absence of a Large, Integrated, and Long-lived Magma Reservoir System

    NASA Astrophysics Data System (ADS)

    Sisson, T. W.; Lanphere, M. A.

    2003-12-01

    Intensive, high-precision K-Ar and 40Ar/39Ar geochronology have proven essential for producing modern geologic maps of volcanoes and from these determining the volcanoes' time-volume histories. If sufficiently abundant, these data can also reveal aspects of the magma supply system. For Cascade volcanoes a general result has been the demonstration that edifice growth is highly episodic. Mount Rainier grew in the last 500,000 years atop the remains of an ancestral edifice that was active in the same location 1 - 2 Myr ago. The 500,000 year history of the modern edifice falls into four stages of alternating high and low magmatic output of subequal duration, but major and trace element compositions of eruptives show no correlation with volcano growth stages. Instead, the same spectrum of magmas (andesite to low-Si dacite) erupted throughout the history of the volcano with compositions in the same relative abundances. Superimposed on this seemingly null result are at least 6 brief but pronounced excursions in magma trace-element compositions. Concentrations of Zr, Ba, or Sr can double and then return to background values passing into and out of a single flow or flow-group. Some excursions are tightly bracketed by mapping and by measured ages and have durations no more than the geochronologic measurement precision of about 10,000 years. True excursion durations are potentially much shorter. The brevity and abrupt onsets and cessations of these compositional excursions are evidence against the presence of a sizeable, long-lived magma reservoir anywhere beneath the volcano, including a MASH zone in the lower crust, that would have attenuated, dampened, and homogenized compositional excursions introduced into the magmatic system. Instead, we take 10,000 years as a probable upper limit to the average residence time of magma batches transiting the crustal portion of Mount Rainier's plumbing system. A consistent scenario is that parental magmas enter the crust, differentiate, assimilate, and either erupt or solidify in less than 10,000 years. Geochronologic evidence from much larger magmatic systems (Reid and coworkers, Long Valley, Yellowstone) suggests that more productive systems can have much longer average residence times than modestly active arc stratovolcanoes like Mt. Rainier.

  10. Effect of Subspine Decompression on Rectus Femoris Integrity and Iliopsoas Excursion: A Cadaveric Study.

    PubMed

    El-Shaar, Rami; Stanton, Michael; Biehl, Scott; Giordano, Brian

    2015-10-01

    To determine the relative influence of anteroinferior iliac spine (AIIS) or subspine decompression on proximal rectus femoris integrity and iliopsoas excursion throughout a physiological range of motion. Nineteen cadaveric hips from 10 specimens were dissected to retain the origin of the rectus femoris direct and indirect heads. The anatomic footprints of the origins were measured with calipers. Serial 5-mm resections of the AIIS were made to determine the extent of proximal tendon disruption that corresponded to each resection. Iliopsoas tendon tracking was also assessed after sequential AIIS decompression by measuring the excursion of the medial border of the iliopsoas tendon as it traveled from its native resting position to the point where it first encountered bony impingement at the AIIS. The mean proximal-distal footprint of the rectus femoris direct head was 17.95 ± 2.99 mm. The mean medial-lateral distance was 11.84 ± 2.34 mm. There was a consistent bare area along the inferior aspect of the AIIS that averaged 4.84 ± 1.42 mm. The average percentage of remaining footprint after each 5-mm resection (5 to 25 mm) was 96%, 65%, 35%, 14%, and 11%, respectively, with statistical significance noted after resections larger than 5 mm (P < .001). The native excursion distance of the iliopsoas tendon was 14.05 mm. With each 5-mm resection, the percentage of excursion before impingement on the AIIS increased by 18%, 45%, 72%, 95%, and 100%, respectively, which was statistically significance after all resections (P < .001). Our study maps the anatomic footprint of the direct head of the rectus femoris tendon and confirms a previously identified bare area along the inferior aspect of the AIIS. Female cadaveric hips had a significantly smaller rectus footprint than male cadavers in our study (P < .001). Subspine decompression greater than 10 mm significantly compromises the rectus femoris origin and should be avoided when performing arthroscopic AIIS decompression. In addition, subspine decompression significantly improves tracking of the iliopsoas tendon throughout a physiological range of motion and may be considered a surgical adjunct when treating symptomatic iliopsoas snapping. Arthroscopic subspine decompression serves as an important treatment modality for AIIS impingement. With a more thorough understanding of AIIS anatomy, subspine decompression can be used to relieve impingement symptoms and possibly improve iliopsoas tracking while safely maintaining rectus femoris footprint integrity. Published by Elsevier Inc.

  11. Delayed recovery from the end-Triassic extinction due to an increase in the extent of ocean anoxia

    NASA Astrophysics Data System (ADS)

    Jost, A. B.; Bachan, A.; van de Schootbrugge, B.; Lau, K. V.; Weaver, K. L.; Maher, K.; Payne, J.

    2015-12-01

    The end-Triassic mass extinction was likely triggered by a rapid rise in pCO2 associated with the emplacement of the Central Atlantic Magmatic Province (CAMP) ca. 201 Ma. Shallow-marine anoxia has long been hypothesized to have caused the extinction and/or delayed the recovery of marine life. However, due to a lack of proxy data, the effects of CAMP emplacement on seawater chemistry remain poorly constrained. Local proxies for anoxia may not reflect widespread ocean redox conditions. However, coupled records of U concentration and isotopic composition (δ238U) in CaCO3 sediments precipitated beneath well-oxygenated bottom waters can potentially serve as a proxy for the global extent of anoxia due to fractionation of U during reduction and associated imbalances in the marine U cycle due to redox changes. We measured δ238U and Th/U values in shallow marine limestones from two stratigraphic sections in the Lombardy Basin, northern Italy, spanning over 400 m, to quantify the change in the extent of ocean anoxia during the end-Triassic extinction. We observe a ca. 0.6‰ negative excursion in δ238U beginning in the lowermost Jurassic, coeval with the onset of the negative δ13C excursion and persisting for the duration of subsequent high δ13C values in the lower-middle Hettangian (earliest Jurassic). Th/U values are generally low at the T/J boundary, peak near the nadir of the δ238U excursion, and steadily return to pre-event values by the end of the measured section. Using a numerical model of the U cycle, we demonstrate that this excursion corresponds to a thirty-fold increase in the extent of anoxia worldwide and a simultaneous increase in the riverine U flux, consistent with increased weathering and eutrophication following massive CO2 injection from CAMP volcanism. Scenarios involving an increase in marine anoxia would also predict higher rates of organic C burial, explaining the large protracted positive δ13C excursion in the lower-mid Hettangian. Recovery of marine fauna, particularly reef builders, was delayed until the late Hettangian, suggesting that environmental conditions were unfavorable for >1 My after the extinction. Uranium isotope data provide strong support for the hypothesis that persistent ocean anoxia inhibited biotic recovery throughout this interval.

  12. Looking for the Kellwasser Event in all the wrong places: a multiproxy study of island arc paleoenvironments in the Central Asian Orogenic Belt

    NASA Astrophysics Data System (ADS)

    Carmichael, S. K.; Wang, Z.; Waters, J. A.; Dombrowski, A. D.; Batchelor, C. J.; Coleman, D. S.; Suttner, T.; Kido, E.

    2017-12-01

    The Late Devonian Frasnian-Famennian (F-F) boundary at 372 Ma is associated with the Kellwasser Event, an ocean anoxia event that is often associated with positive δ13C excursions and commonly represented by black shales. However, approximately 88% of the studies of the Kellwasser Event are based on sites from deep epicontinental basins and epeiric seas, and most of these sites are located on the Euramerican paleocontinent. In contrast to the positive δ13C excursions found in most basinal study sites, the δ13C signatures in three separate shallow water, island-arc F-F sections in the Junggar Basin in northwestern China (Wulankeshun, Boulongour Reservoir, and Genare) all show negative excursions in the stratigraphic location of the Kellwasser Event [1-3]. The δ18O values in both carbonates and/or conodont apatite likewise show negative excursions within the shallow water facies at each site, but have relatively constant signatures within the deeper water facies. 87Sr/86Sr values range from 0.70636-0.70906 at the base of the Boulongour Reservoir section and 0.70746-0.71383 at the base of the Wulankeshun section but both Sr signaures stabilize with relatively constant values closer to modeled Late Devonian seawater in deeper water and/or offshore facies. The fossil assemblages at the base of the Boulongour and Wulankeshun sections each correspond to euryhaline/brackish conditions, while microtextures in Ti-bearing phases within clastic sediments as well as isotope mixing models suggest submarine groundwater discharge signatures rather than diagenetic alteration. Preliminary framboidal pyrite distributions in these sections also show evidence for sub/dysoxic (rather than euxinic or anoxic) conditions that correspond to the stratigraphic Kellwasser interval. Positive δ13C excursions and the presence of black shales are thus not prerequisites for recognition of the Kellwasser Event, particularly in shallow water paleoenvironments that are not topographically favorable to shale accumulation and may have significant coastal groundwater or surface water inputs. [1] Suttner et al. (2014) J. of Asian Earth Sci. 80, 101-118. [2] Carmichael et al. (2014) Paleo3 399, 394-403. [3] Wang et al. (2016) Paleo3 448, 279-297.

  13. Comparison of Glycemic Excursion in Patients with New Onset Type 2 Diabetes Mellitus before and after Treatment with Repaglinide.

    PubMed

    Hezarkhani, Sharabeh; Bonakdaran, Shokufeh; Rajabian, Reza; Shahini, Najmeh; Marjani, Abdoljalal

    2013-01-01

    Due to industrialization and sedentary life, incidence of type 2 diabetes (DM2) is increasing seriously. Repaglinide is a glucose reducing agent that predominantly reduces post-prandial glucose. Continuous glucose monitoring system (CGMS) monitors blood glucose excursions over a 3-day period. CGMS can be used as a therapeutic and diagnostic instrument in diabetics. There are not enough studies about using CGMS in DM2. The aim of this study was to determine the blood glucose excursions in patients with new onset of DM2. 10 patients with new onset of DM2 were entered to this study. As the first therapeutic management, patients received diabetic diet and moderate exercise for 3-weeks, if they did not achieve blood glucose goal (Fasting blood glucoser (FBG) <120mg/dl, 2-hour postprandial blood glucose (2hpp) <180mg/dl), were considered to undergo 3-days CGMS at baseline and after 4-weeks on Repaglinide (0.5mg three times before meals). Mean excursions of blood glucose were not different at the onset and at the end of treatment (6±4.05 VS 7.6±5.2 episodes, P=0.49). There were also no significant differences between mean duration of hypoglycemic episodes (zero VS 5.1±14.1 hours, P =0.28) and hyperglycemic episodes before and after therapy (7.6±5.2 VS 5.7±4.1, P=0.42), but mean hyperglycemia duration was significantly reduced at the end of therapy (21±26.17 VS 57.7±35.3, P=0.001). Patients experienced a mean of 0.3±0.67 episodes of hypoglycemia after therapy showed no significant difference before it (P =0.19). Mean FBG (with CGMS) was significantly lower after therapy than before it (142.9±54.31 VS 222.9±82.6, P <0.001). This study showed the usefulness of CGMS not only as a diagnostic but also as an educational and therapeutic tool that in combination with Repaglinide (with the lowest effective dose and duration) can significantly reduce FBG and glycemic excursions in DM2 patients and hypoglycemic events are low.

  14. Euxinia prior to end-Permian main extinction at Xiaojiaba section, Sichuan Province, South China

    NASA Astrophysics Data System (ADS)

    Wei, H.; Algeo, T. J.; Chen, D.; Yu, H.

    2013-12-01

    Redox conditions in the global ocean prior to, during, and following the end-Permian mass extinction at 252.28 Ma remain contentious. Previous studies in western Australia, South China, and East Greenland have shown that photic-zone euxinia was present at least intermittently from the early Changhsingian through the Dienerian1-3. Here we report a study of organic carbon isotopes, pyrite sulfur isotopes, TOC, pyritic sulfur content, REE, and major and trace elements from the Upper Permian Xiaojiaba section in the Chaotian district of Guangyuan City, Sichuan Province, China. During the Permian-Triassic transition, this section was located on the northwestern margin of the South China Block, facing the Paleo-Tethys Ocean. Our results indicate that suboxic conditions prevailed during the Wuchiapingian and suboxic to anoxic conditions with several pulses of euxinia during the Changhsingian. δ13Corg values are mostly -28‰ to -26‰ but show three positive excursions (to -22‰) prior to the end-Permian mass extinction horizon. These positive excursions are associated with higher Spy concentrations (to ~1%). δ34Spy values are variable (from -41‰ to +5‰) but show a sharp negative excursion in the late Changhsingian (to -43.4‰) that coincided with the most positive δ13Corg values. This horizon is also associated with increases in Eu/Eu*, Baxs, ∑REE, Si, and redox-sensitive metals such as V. These patterns reflect linkage of the C and S cycles during the latest Permian, possibly in response to redox controls. The observed positive excursions in δ13Corg may be due to organic inputs from green sulfur bacteria, which exhibit a smaller photosynthetic fractionation (-12.5‰4) than eukaryotic algae. The pronounced negative excursion of δ34Spy corresponds to a sulfate-sulfide S isotope fractionation of about -60‰, suggesting a large flux of syngenetic framboidal pyrite, which would be indicative of euxinic water-column conditions. We infer that the euxinia prior to the main extinction horizon may have been caused by oceanic oxygen-minimum zone expansion and upward movement of the chemocline5. The coupled increases in Eu/Eu* and Baxs may record hydrothermal influence, possibly accompanied by increased ocean acidity and high seawater temperatures. Collectively, our results document major changes in seawater chemistry during the Changhsingian prior to the main end-Permian crisis.

  15. Impact of multiple joint impairments on the energetics and mechanics of walking in patients with haemophilia.

    PubMed

    Lobet, S; Detrembleur, C; Hermans, C

    2013-03-01

    Few studies have assessed the changes produced by multiple joint impairments (MJI) of the lower limbs on gait in patients with haemophilia (PWH). In patients with MJI, quantifiable outcome measures are necessary if treatment benefits are to be compared. This study was aimed at observing the metabolic cost, mechanical work and efficiency of walking among PWH with MJI and to investigate the relationship between joint damage and any changes in mechanical and energetic variables. This study used three-dimensional gait analysis to investigate the kinematics, cost, mechanical work and efficiency of walking in 31 PWH with MJI, with the results being compared with speed-matched values from a database of healthy subjects. Regarding energetics, the mass-specific net cost of transport (C(net)) was significantly higher for PWH with MJI compared with control and directly related to a loss in dynamic joint range of motion. Surprisingly, however, there was no substantial increase in mechanical work, with PWH being able to adopt a walking strategy to improve energy recovery via the pendulum mechanism. This probable compensatory mechanism to economize energy likely counterbalances the supplementary work associated with an increased vertical excursion of centre of mass (CoM) and lower muscle efficiency of locomotion. Metabolic variables were probably the most representative variables of gait disability for these subjects with complex orthopaedic degenerative disorders. © 2012 Blackwell Publishing Ltd.

  16. A non-contact measurement technique at the micro scale

    NASA Astrophysics Data System (ADS)

    Ghosh, Santaneel

    During their production and normal use, electronic packages experience large temperature excursions, leading to high thermo-mechanical stress gradients that cause fatigue failure of the solder joints. In order to prevent premature failure and prolong the fatigue life of solder joints, there is a pressing need for the characterization of the solder, especially lead-free solder, at the micro-level (joint size). The characterization and modeling of solder behavior at the appropriate scale is a major issue. However, direct measurement techniques are not applicable to characterize the deformation response of solder joints because of their micro scale dimensions. Therefore, a non-contact measurement technique utilizing a Scanning Electron Microscope (SEM) in conjunction with Digital Image Correlation (DIC) has been developed. Validation was achieved by performing a four-point bending test in both an in-house optical system with DIC and inside the SEM. This non-contact measurement technique was then used to extract the stress-strain response of the solder. Mechanical tests were performed on solder joints that were created using the same type of solder balls used in the electronic industry and were representative of normal joint scales. The SEM-DIC technique has been proven to be applicable for the determining the stress-strain response of solder material at the micro-scale. This study resulted in a validated material characterization technique specifically designed for micro-scale material response. One of the main contributions of this study is that the method is a lot simpler and cheaper, yet highly effective, compared to the previous methods. This technique is also readily applicable to the measurement of the stress-strain response of any micro-scale specimen, such as other metals, polymers, etc. Also, the measured displacement field by obtained by DIC can be used as the base for calculating the strain field on the surface of a specimen.

  17. Socioeconomic disparities in the utilization of mechanical thrombectomy for acute ischemic stroke in US hospitals.

    PubMed

    Brinjikji, W; Rabinstein, A A; McDonald, J S; Cloft, H J

    2014-03-01

    Previous studies have demonstrated that socioeconomic disparities in the treatment of cerebrovascular diseases exist. We studied a large administrative data base to study disparities in the utilization of mechanical thrombectomy for acute ischemic stroke. With the utilization of the Perspective data base, we studied disparities in mechanical thrombectomy utilization between patient race and insurance status in 1) all patients presenting with acute ischemic stroke and 2) patients presenting with acute ischemic stroke at centers that performed mechanical thrombectomy. We examined utilization rates of mechanical thrombectomy by race/ethnicity (white, black, and Hispanic) and insurance status (Medicare, Medicaid, self-pay, and private). Multivariate logistic regression analysis adjusting for potential confounding variables was performed to study the association between race/insurance status and mechanical thrombectomy utilization. The overall mechanical thrombectomy utilization rate was 0.15% (371/249,336); utilization rate at centers that performed mechanical thrombectomy was 1.0% (371/35,376). In the sample of all patients with acute ischemic stroke, multivariate logistic regression analysis demonstrated that uninsured patients had significantly lower odds of mechanical thrombectomy utilization compared with privately insured patients (OR = 0.52, 95% CI = 0.25-0.95, P = .03), as did Medicare patients (OR = 0.53, 95% CI = 0.41-0.70, P < .0001). Blacks had significantly lower odds of mechanical thrombectomy utilization compared with whites (OR = 0.35, 95% CI = 0.23-0.51, P < .0001). When considering only patients treated at centers performing mechanical thrombectomy, multivariate logistic regression analysis demonstrated that insurance was not associated with significant disparities in mechanical thrombectomy utilization; however, black patients had significantly lower odds of mechanical thrombectomy utilization compared with whites (OR = 0.41, 95% CI = 0.27-0.60, P < .0001). Significant socioeconomic disparities exist in the utilization of mechanical thrombectomy in the United States.

  18. Sensitivity analysis of reactive ecological dynamics.

    PubMed

    Verdy, Ariane; Caswell, Hal

    2008-08-01

    Ecological systems with asymptotically stable equilibria may exhibit significant transient dynamics following perturbations. In some cases, these transient dynamics include the possibility of excursions away from the equilibrium before the eventual return; systems that exhibit such amplification of perturbations are called reactive. Reactivity is a common property of ecological systems, and the amplification can be large and long-lasting. The transient response of a reactive ecosystem depends on the parameters of the underlying model. To investigate this dependence, we develop sensitivity analyses for indices of transient dynamics (reactivity, the amplification envelope, and the optimal perturbation) in both continuous- and discrete-time models written in matrix form. The sensitivity calculations require expressions, some of them new, for the derivatives of equilibria, eigenvalues, singular values, and singular vectors, obtained using matrix calculus. Sensitivity analysis provides a quantitative framework for investigating the mechanisms leading to transient growth. We apply the methodology to a predator-prey model and a size-structured food web model. The results suggest predator-driven and prey-driven mechanisms for transient amplification resulting from multispecies interactions.

  19. Investigating The Kinematics of Canids and Felids

    NASA Astrophysics Data System (ADS)

    Sur, D.

    2016-12-01

    For all organisms, metabolic energy is critical for survival. While moving efficiently is a necessity for large carnivores, the influence of kinematics on energy demand remains poorly understood. We measured the kinematics of dogs, wolves, and pumas to detect any differences in their respective energy expenditures. Using 22 kinematic parameters measured on 78 videos, we used one-way ANOVAs and paired T-tests to compare 5 experimental treatments among gaits in dogs (n=11 in 3 breed groups), wolves (n=2), and pumas (n=2). Across the measured parameters, we found greater kinematic similarity than expected among dog breeds and no trend in any of the 22 parameters regarding the effect of steepness on locomotion mechanics. Similarly, treadmill kinematics were nearly identical to those measured during outdoor movement. However, in 3 inches of snow, we observed significant differences (p<0.05) in 5 of the 22 parameters for one wolf. When comparing canids (wolves and dogs) to a felid (pumas), we found that pumas and dogs are the most kinematically distinct (differing in 13 of 22 parameters, compared with 5 of 22 for wolves and pumas). Lastly, compared with wolves, walking pumas had larger head angles (p=0.0025), forelimb excursion angles (p=0.0045), and hindlimb excursion angles (p=0.0327). After comparing the energetics of pumas and dogs with their respective kinematics, we noted that less dynamic kinematics result in energy savings. Through tracking the locations and gait behavior of large carnivores, novel sensor technology can reveal how indoor kinematics applies to wild animals and improve the conservation of these species.

  20. A volcanic wind-stress origin of the Atlantic Multidecadal Oscillation

    NASA Astrophysics Data System (ADS)

    Birkel, S. D.; Mayewski, P. A.; Maasch, K. A.; Auger, J.; Lyon, B.

    2016-12-01

    The Atlantic Multidecadal Oscillation (AMO) is a mode of sea-surface temperature (SST) variability in the North Atlantic that has significant impact on global climate. Most previous studies ascribe the origin of the AMO to oceanic mechanisms, and suggest only a limited role for the atmosphere. Here, we suggest that the AMO is manifested from basin-wide changes in surface wind stress that arise in response to episodic volcanic activity. Our interpretation is based on historical SST, reanalysis, and stratospheric aerosol optical thickness data, wherein it is evident that cool (warm) intervals of the AMO coincide with emergence of strong (weak) winds and high (low) volcanic activity. We find that SST excursions ultimately develop from atmospheric forcing as volcanic events project onto the North Atlantic Oscillation (NAO). A volcanic signature is particularly evident beneath the westerlies in the subpolar region south of Greenland, where several large SST excursions occur coincident with identifiable major eruptions. High latitude surface waters cool when NAO+ circulation, which includes a deepened Icelandic Low, draws cold flow out of the Labrador Sea and into the subpolar region. Important feedbacks that cause SST anomalies to spread across the basin include cloud cover, wind-driven upwelling, and entrainment of Saharan dust into the tropical easterlies. Finally, we speculate that cooling in the North Atlantic observed since 2011 could be linked to renewed volcanic activity over Iceland, namely from the eruptions of Grímsvötn (2011) and Bárðarbunga (2014). An important question remains how North Atlantic SST variability will evolve as atmospheric circulation becomes increasingly modified by human activity.

  1. Interlimb Differences in Coordination of Unsupported Reaching Movements

    PubMed Central

    Schaffer, Jacob E.; Sainburg, Robert L.

    2017-01-01

    Previous research suggests that interlimb differences in coordination associated with handedness might result from specialized control mechanisms that are subserved by different cerebral hemispheres. Based largely on the results of horizontal plane reaching studies, we have proposed that the hemisphere contralateral to the dominant arm is specialized for predictive control of limb dynamics, while the non-dominant hemisphere is specialized for controlling limb impedance. The current study explores interlimb differences in control of 3-D unsupported reaching movements. While the task was presented in the horizontal plane, participant’s arms were unsupported and free to move within a range of the vertical axis, which was redundant to the task plane. Results indicated significant dominant arm advantages for both initial direction accuracy and final position accuracy. The dominant arm showed greater excursion along a redundant axis that was perpendicular to the task, and parallel to gravitational forces. In contrast, the non-dominant arm better impeded motion out of the task-plane. Nevertheless, left arm task errors varied substantially more with shoulder rotation excursion than did dominant arm task errors. These findings suggest that the dominant arm controller was able to take advantage of the redundant degrees of freedom of the task, while non-dominant task errors appeared enslaved to motion along the redundant axis. These findings are consistent with a dominant controller that is specialized for intersegmental coordination, and a non-dominant controller that is specialized for impedance control. However, the findings are inconsistent with previously documented conclusions from planar tasks, in which non-dominant control leads to greater final position accuracy. PMID:28344068

  2. Advanced Seal Development for Large Industrial Gas Turbines

    NASA Technical Reports Server (NTRS)

    Chupp, Raymond E.

    2006-01-01

    Efforts are in progress to develop advanced sealing for large utility industrial gas turbine engines (combustion turbines). Such seals have been under developed for some time for aero gas turbines. It is desired to transition this technology to combustion turbines. Brush seals, film riding face and circumferential seals, and other dynamic and static sealing approaches are being incorporated into gas turbines for aero applications by several engine manufacturers. These seals replace labyrinth or other seals with significantly reduced leakage rates. For utility industrial gas turbines, leakage reduction with advanced sealing can be even greater with the enormous size of the components. Challenges to transitioning technology include: extremely long operating times between overhauls; infrequent but large radial and axial excursions; difficulty in coating larger components; and maintenance, installation, and durability requirements. Advanced sealing is part of the Advanced Turbine Systems (ATS) engine development being done under a cooperative agreement between Westinghouse and the US Department of Energy, Office of Fossil Energy. Seal development focuses on various types of seals in the 501ATS engine both at dynamic and static locations. Each development includes rig testing of candidate designs and subsequent engine validation testing of prototype seals. This presentation gives an update of the ongoing ATS sealing efforts with special emphasis on brush seals.

  3. The Habitat Demonstration Unit System Integration

    NASA Technical Reports Server (NTRS)

    Gill, Tracy R.; Kennedy, Kriss J.; Tri, Terry O.; Howe, Alan S.

    2010-01-01

    The Lunar Surface System Habitat Demonstration Unit (HDU) will require a project team to integrate a variety of contributions from National Aeronautics and Space Administration (NASA) centers and potential outside collaborators and poses a challenge in integrating these disparate efforts into a cohesive architecture. To accomplish the development of the first version of the HDU, the Pressurized Excursion Module (PEM), from conception in June 2009 to rollout for operations in July 2010, the HDU project team is using several strategies to mitigate risks and bring the separate efforts together. First, a set of design standards is being developed to define the interfaces between the various systems of PEM and to the payloads, such as the Geology Laboratory, that those systems will support. Scheduled activities such as early fit-checks and the utilization of a habitat avionics test bed prior to equipment installation into HDU PEM are planned to facilitate the integration process. A coordinated effort to establish simplified Computer Aided Design (CAD) standards and the utilization of a modeling and simulation systems will aid in design and integration concept development. Finally, decision processes on the shell development including the assembly sequence and the transportation have been fleshed out early on HDU design to maximize the efficiency of both integration and field operations.

  4. Lunar Excursion Model in Full Scale Wind Tunnel. Apollo Project. Bell Lunar Landing Training Vehicle (LLTV)

    NASA Image and Video Library

    1969-01-16

    Concept model of the Lunar Excursion Module tested in the Full-Scale wind tunnel. -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995), p. 356.-L69-670 Bell Lunar Landing Training Vehicle (LLTV): Following the crash of a sister Lunar Landing Training Vehicle at Ellington Field in Houston, Texas, the LLTV NASA 952 was sent from Houston to Langley for tests in the 30 x 60 Full Scale Tunnel. The LLTV was returned to Houston for further training use a short time later. NASA 952 is now on exhibit at the Johnson Space Center in Houston, Texas.

  5. Variations of the earth's magnetic field and rapid climatic cooling: A possible link through changes in global ice volume

    NASA Technical Reports Server (NTRS)

    Rampino, M. R.

    1979-01-01

    A possible relationship between large scale changes in global ice volume, variations in the earth's magnetic field, and short term climatic cooling is investigated through a study of the geomagnetic and climatic records of the past 300,000 years. The calculations suggest that redistribution of the Earth's water mass can cause rotational instabilities which lead to geomagnetic excursions; these magnetic variations in turn may lead to short-term coolings through upper atmosphere effects. Such double coincidences of magnetic excursions and sudden coolings at times of ice volume changes have occurred at 13,500, 30,000, 110,000, and 135,000 YBP.

  6. Road guide to geological points of interest on the island of Hawaii

    NASA Technical Reports Server (NTRS)

    Stearns, H. T.; Macdonald, G. A.; Greeley, R.

    1974-01-01

    This road guide briefly describes the points of geologic interest along the main roads on Hawaii. It begins at Hilo and proceeds around the island in a clockwise direction on State Route 11 to Kailua, then returns to Hilo on State Route 19 to Hilo via Waimea, with side excursions on the other principal roads. Minimum excursion time is two days, allowing only very brief time for the various stops. The return to Hilo from Waimea can be made via Route 19 along the Hamakua Coast (wet, leeward side of island, displaying typical tropical erosion) or via Route 20 over the Humuula Saddle (high, relatively dry and cool; young volcanic features).

  7. Unexpected Southern Hemisphere ionospheric response to geomagnetic storm of 15 August 2015

    NASA Astrophysics Data System (ADS)

    Edemskiy, Ilya; Lastovicka, Jan; Buresova, Dalia; Bosco Habarulema, John; Nepomnyashchikh, Ivan

    2018-01-01

    Geomagnetic storms are the most pronounced phenomenon of space weather. When studying ionospheric response to a storm of 15 August 2015, an unexpected phenomenon was observed at higher middle latitudes of the Southern Hemisphere. This phenomenon was a localized total electron content (TEC) enhancement (LTE) in the form of two separated plumes, which peaked southward of South Africa. The plumes were first observed at 05:00 UT near the southwestern coast of Australia. The southern plume was associated with local time slightly after noontime (1-2 h after local noon). The plumes moved with the Sun. They peaked near 13:00 UT southward of South Africa. The southern plume kept constant geomagnetic latitude (63-64° S); it persisted for about 10 h, whereas the northern plume persisted for about 2 h more. Both plumes disappeared over the South Atlantic Ocean. No similar LTE event was observed during the prolonged solar activity minimum period of 2006-2009. In 2012-2016 we detected altogether 26 LTEs and all of them were associated with the southward excursion of Bz. The negative Bz excursion is a necessary but not sufficient condition for the LTE occurrence as during some geomagnetic storms associated with negative Bz excursions the LTE events did not appear.

  8. Horizontal and vertical movements of Caribbean reef sharks (Carcharhinus perezi): conservation implications of limited migration in a marine sanctuary

    PubMed Central

    Howey, Lucy A.; Tolentino, Emily R.; Jordan, Lance K. B.; Ruppert, Jonathan L. W.; Brooks, Edward J.

    2017-01-01

    Despite the ecological and economic importance of the Caribbean reef shark (Carcharhinus perezi), little data exist regarding the movements and habitat use of this predator across its range. We deployed 11 pop-up satellite archival tags on Caribbean reef sharks captured in the northeast Exuma Sound, The Bahamas, to assess their horizontal and vertical movements throughout the water column. Sharks showed high site fidelity to The Bahamas suggesting Bahamian subpopulations remain protected within the Bahamian Shark Sanctuary. Depth data indicate that Caribbean reef sharks spent a significant proportion (72–91%) of their time above 50 m in narrow vertical depth bands, which varied considerably on an individual basis. This may be indicative of high site fidelity to specific bathymetric features. Animals exhibited three broadly categorized sporadic off-bank excursions (more than 50 m excursions) down to a depth of 436.1 m, which were more frequent during the night. These deeper excursions during night may be indicative of foraging in relation to prey on mesophotic reefs, as well as diel-vertically migrating prey from the deeper meso- and bathypelagic zones. These vertical movements suggest that Caribbean reef sharks can be significant vectors of ecosystem connectivity further warranting holistic multi-system management and conservation approaches. PMID:28386422

  9. Noise-induced switching near a depth two heteroclinic network and an application to Boussinesq convection.

    PubMed

    Ashwin, Peter; Podvigina, Olga

    2010-06-01

    We investigate the robust heteroclinic dynamics arising in a system of ordinary differential equations in R(4) with symmetry [Formula in text]. This system arises from the normal form reduction of a 1: squate root of 2 mode interaction for Boussinesq convection. We investigate the structure of a particular robust heteroclinic attractor with "depth two connections" from equilibria to subcycles as well as connections between equilibria. The "subcycle" is not asymptotically stable, due to nearby trajectories undertaking an "excursion," but it is a Milnor attractor, meaning that a positive measure set of nearby initial conditions converges to the subcycle. We investigate the dynamics in the presence of noise and find a number of interesting properties. We confirm that typical trajectories wind around the subcycle with very occasional excursions near a depth two connection. The frequency of excursions depends on noise intensity in a subtle manner; in particular, for anisotropic noise, the depth two connection may be visited much more often than for isotropic noise, and more generally the long term statistics of the system depends not only on the noise strength but also on the anisotropy of the noise. Similar properties are confirmed in simulations of Boussinesq convection for parameters giving an attractor with depth two connections. (c) 2010 American Institute of Physics.

  10. Horizontal and vertical movements of Caribbean reef sharks (Carcharhinus perezi): conservation implications of limited migration in a marine sanctuary.

    PubMed

    Shipley, Oliver N; Howey, Lucy A; Tolentino, Emily R; Jordan, Lance K B; Ruppert, Jonathan L W; Brooks, Edward J

    2017-02-01

    Despite the ecological and economic importance of the Caribbean reef shark ( Carcharhinus perezi ), little data exist regarding the movements and habitat use of this predator across its range. We deployed 11 pop-up satellite archival tags on Caribbean reef sharks captured in the northeast Exuma Sound, The Bahamas, to assess their horizontal and vertical movements throughout the water column. Sharks showed high site fidelity to The Bahamas suggesting Bahamian subpopulations remain protected within the Bahamian Shark Sanctuary. Depth data indicate that Caribbean reef sharks spent a significant proportion (72-91%) of their time above 50 m in narrow vertical depth bands, which varied considerably on an individual basis. This may be indicative of high site fidelity to specific bathymetric features. Animals exhibited three broadly categorized sporadic off-bank excursions (more than 50 m excursions) down to a depth of 436.1 m, which were more frequent during the night. These deeper excursions during night may be indicative of foraging in relation to prey on mesophotic reefs, as well as diel-vertically migrating prey from the deeper meso- and bathypelagic zones. These vertical movements suggest that Caribbean reef sharks can be significant vectors of ecosystem connectivity further warranting holistic multi-system management and conservation approaches.

  11. Evidence of Methane Outgassing During MIS3 in the Bering Sea

    NASA Astrophysics Data System (ADS)

    Cook, M. S.; Keigwin, L. D.

    2005-12-01

    There are multiple negative excursions in planktonic and benthic foraminifer δ13C in a core from 1467m in the southeast Bering Sea. These excursions occur episodically during the last glacial period, and may coincide with Dansgaard-Oeschger (D-O) events. Measured foraminifer δ13C during the excursions is as low as -14‰ and are probably the result of overgrowths of diagenetic calcium carbonate. We estimate overgrowth δ13C is -23‰, and hypothesize that the occurrence of overgrowths is associated with anaerobic oxidation of biogenic methane. The likely pressure and temperature conditions at this site and during the last glacial period were well within the zone of methane-hydrate stability, so the source of methane is probably not from destabilization of methane hydrate at this depth. The methane may have originated from increased in-situ methanogenesis resulting from greater burial of organic carbon, or from destabilization of methane hydrate at shallower sites near the methane-hydrate stability threshold. Both these scenarios could be active, consistent with the ``Clathrate Gun Hypothesis'' (Kennett et al., 2003), in which there is widespread destabilization of marine methane hydrates during D-O events, where methane gas both is oxidized within the water column and escapes to the atmosphere.

  12. Aeroelastic airfoil smart spar

    NASA Technical Reports Server (NTRS)

    Greenhalgh, Skott; Pastore, Christopher M.; Garfinkle, Moishe

    1993-01-01

    Aircraft wings and rotor-blades are subject to undesirable bending and twisting excursions that arise from unsteady aerodynamic forces during high speed flight, abrupt maneuvers, or hard landings. These bending excursions can range in amplitude from wing-tip flutter to failure. A continuous-filament construction 'smart' laminated composite box-beam spar is described which corrects itself when subject to undesirable bending excursions or flutter. The load-bearing spar is constructed so that any tendency for the wing or rotor-blade to bend from its normal position is met by opposite twisting of the spar to restore the wing to its normal position. Experimental and theoretical characterization of these spars was made to evaluate the torsion-flexure coupling associated with symmetric lay-ups. The materials used were uniweave AS-4 graphite and a matrix comprised of Shell 8132 resin and U-40 hardener. Experimental tests were conducted on five spars to determine spar twist and bend as a function of load for 0, 17, 30, 45 and 60 deg fiber angle lay-ups. Symmetric fiber lay-ups do exhibit torsion-flexure couplings. Predictions of the twist and bend versus load were made for different fiber orientations in laminated spars using a spline function structural analysis. The analytical results were compared with experimental results for validation. Excellent correlation between experimental and analytical values was found.

  13. An 84-kyr paleomagnetic record from the sediments of Lake Baikal, Siberia

    USGS Publications Warehouse

    Peck, J.A.; King, J.W.; Colman, Steven M.; Kravchinsky, V.A.

    1996-01-01

    We have conducted a paleomagnetic study of sediment cores obtained from the Selenga prodelta region of Lake Baikal, Russia. This record, which spans approximately the last 84 kyr, contributes to a better understanding of the nature of geomagnetic field behavior in Siberia and is a useful correlation and dating tool. We demonstrate that the Lake Baikal sediments are recording variations in the geomagnetic field. The directional record displays secular variation behavior with a geomagnetic excursion at 20 ka and additional excursions appearing as large-amplitude secular variation at 41, 61, and 67 ka. Smoothing of the geomagnetic excursion behavior occurs in Lake Baikal sediments owing to the intermediate sedimentation rate (13 cm kyr-1). The Lake Baikal relative paleointensity record correlates to absolute paleointensity data for the last 10 kyr and to relative paleointensity records from the Mediterranean Sea and Indian Ocean for the last 84 kyr. This correlation suggests a strong global (i.e., dipole) component to these records and further supports the reliability of sediments as recorders of relative geomagnetic paleointensity. We show that a relative geomagnetic intensity stratigraphy has a potential resolution of 7 kyr by correlating continental and marine records. The geomagnetic intensity stratigraphy helps constrain the age of the difficult to date Lake Baikal sediments.

  14. Correlation of electrical reactor cable failure with materials degradation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stuetzer, O.M.

    1986-03-01

    Complete circuit failure (shortout) of electrical cables typically used in nuclear power plant containments is investigated. Failure modes are correlated with the mechanical deterioration of the elastomeric cable materials. It is found that for normal reactor operation, electrical cables are reliable and safe over very long periods. During high temperature excursions, however, cables pulled across corners under high stress may short out due to conductor creep. Severe cracking will occur in short times during high temperatures (>150/sup 0/C) and in times of the order of years at elevated temperatures (100/sup 0/C to 140/sup 0/C). A theoretical treatment of stress distributionmore » responsible for creep and for cracking by J.E. Reaugh of Science Applications, Inc. is contained in the Appendix. 29 refs., 32 figs.« less

  15. Alteration of travel patterns with vision loss from glaucoma and macular degeneration.

    PubMed

    Curriero, Frank C; Pinchoff, Jessie; van Landingham, Suzanne W; Ferrucci, Luigi; Friedman, David S; Ramulu, Pradeep Y

    2013-11-01

    The distance patients can travel outside the home influences how much of the world they can sample and to what extent they can live independently. Recent technological advances have allowed travel outside the home to be directly measured in patients' real-world routines. To determine whether decreased visual acuity (VA) from age-related macular degeneration (AMD) and visual field (VF) loss from glaucoma are associated with restricted travel patterns in older adults. Cross-sectional study. Patients were recruited from an eye clinic, while travel patterns were recorded during their real-world routines using a cellular tracking device. Sixty-one control subjects with normal vision, 84 subjects with glaucoma with bilateral VF loss, and 65 subjects with AMD with bilateral or severe unilateral loss of VA had their location tracked every 15 minutes between 7 am and 11 pm for 7 days using a tracking device. Average daily excursion size (defined as maximum distance away from home) and average daily excursion span (defined as maximum span of travel) were defined for each individual. The effects of vision loss on travel patterns were evaluated after controlling for individual and geographic factors. In multivariable models comparing subjects with AMD and control subjects, average excursion size and span decreased by approximately one-quarter mile for each line of better-eye VA loss (P ≤ .03 for both). Similar but not statistically significant associations were observed between average daily excursion size and span for severity of better-eye VF loss in subjects with glaucoma and control subjects. Being married or living with someone and younger age were associated with more distant travel, while less-distant travel was noted for older individuals, African Americans, and those living in more densely populated regions. Age-related macular degeneration-related loss of VA, but not glaucoma-related loss of VF, is associated with restriction of travel to more nearby locations. This constriction of life space may impact quality of life and restrict access to services.

  16. New high resolution geochemistry of Lower Jurassic marine sections in western North America: A global positive carbon isotope excursion in the Sinemurian?

    NASA Astrophysics Data System (ADS)

    Porter, Sarah J.; Smith, Paul L.; Caruthers, Andrew H.; Hou, Pengfei; Gröcke, Darren R.; Selby, David

    2014-07-01

    Recognising variations in the carbon isotope compositions of marine organic-rich sedimentary rocks can provide insight into changes in ocean chemistry throughout geological time. Further, identification of global excursions in the carbon isotope record has proved to be valuable as a chronostratigraphic correlation tool. This investigation presents new high-resolution organic carbon isotope data (δCorg13) for marine sediments from 2 regions in North America (Last Creek, British Columbia, Canada and Five Card Draw, Nevada, USA). The carbon isotope profiles demonstrate that there were significant differences between the carbon reservoirs at Five Card Draw and Last Creek, notably in the upper part of the Leslei Zone. The δCorg13 values show a gradual positive CIE (∼2‰) at Last Creek in the upper part of the Leslei Zone. This corresponds to a coeval positive CIE of similar duration in Dorset, UK (upper Turneri Zone; Jenkyns and Weedon, 2013), suggesting that this may be a global marine carbon isotope signature, and likely reflects a widespread increase in primary productivity during the Early Sinemurian. In addition, a brief negative CIE is observed in the uppermost Lower Sinemurian at Last Creek. This negative excursion is not recorded in the Dorset section, suggesting localised upwelling of 12C-rich bottom-waters at Last Creek. Further, the signals identified at Last Creek are not present in coeval sections at Five Card Draw, thus highlighting a significant difference between these localities. Osmium (Os) isotope data (initial 187Os/188Os values) provide a quantitative determination of the contrasting depositional environments of Five Card Draw and Last Creek (at least partially restricted with high levels of continental inundation and open-ocean, respectively). This demonstrates that basinal restriction may act as a major factor that controls isotopic stratigraphic signatures, thus preventing the identification of global or widespread regional excursions.

  17. An Ocean Acidification Pulse in the Pre-onset Carbon Isotope Excursion Preceding the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Robinson, M. M.; Self-Trail, J. M.; Willard, D. A.; Stassen, P.; Spivey, W.

    2015-12-01

    The Paleocene-Eocene Thermal Maximum (PETM; ~55.5 Ma) is recognized globally in marine sediments by a carbonate dissolution zone, the extinction or turnover of benthic taxa, and a radiation of planktic excursion taxa, all accompanied by a rapid-onset, negative carbon isotope excursion (CIE). The cause and nature of the massive carbon release leading to this extreme climate event remains under debate. Regardless of cause, the environmental and ecosystem changes centered on the PETM are the subject of much study because they provide an analog to modern deteriorating conditions associated with the ongoing rise in atmospheric carbon dioxide. We present evidence from sediments of the South Dover Bridge core, deposited on the U.S. mid-Atlantic shelf, for an ocean acidification event in the latest Paleocene that coincides with a relatively small (-2‰) negative carbon isotope excursion (CIE) that precedes the larger (-4‰) Paleocene-Eocene CIE onset. Planktic foraminifers during this pre-onset event (POE) show post-deposition dissolution in which the coarsely cancellate and muricate wall textures characteristic of many Late Paleocene species have been dissolved away, leaving smooth, thin-walled specimens often with collapsed chambers. In addition, we document biotic responses in benthic, planktic, and terrestrial communities to the POE, including shifts in foraminifer and pollen assemblages and adaptations in calcareous nannofossil species in response to environmental perturbations. A complete recovery is evident between the POE and CIE in both the carbon isotopic signal and in the biotic response, providing additional evidence not only for a pulsed carbon release, but also for a more rapid rate of carbon release than is suggested by a single pulse over a longer period of time. The timing, nature and magnitude of ecological changes during the less extreme POE shallow water acidification event may help to define the ecological tipping point of shallow marine ecosystems.

  18. Improving balance skills in patients who had stroke through virtual reality treadmill training.

    PubMed

    Yang, Saiwei; Hwang, Wei-Hsung; Tsai, Yi-Ching; Liu, Fu-Kang; Hsieh, Lin-Fen; Chern, Jen-Suh

    2011-12-01

    The aim of this study was to evaluate the effects of virtual reality (VR) treadmill training on the balance skills of patients who have had a stroke. A total of 14 patients with strokes were recruited and randomly assigned to receive VR treadmill or traditional treadmill training. The outcome measures that were included for the study were center of pressure (COP) sway excursion, COP maximum sway in anterior-posterior direction, COP maximum sway in medial-lateral direction, COP sway area, bilateral limb-loading symmetric index, the sway excursion values for the paretic foot (sway excursion/P), paretic limb stance time (stance time/P), number of steps of the paretic limb (number of steps/P), and contact area of the paretic foot (contact A/P) during quiet stance, sit-to-stand transfer, and level walking. There were no significant improvements in COP-related measures and symmetric index during the quiet stance, either in the VR treadmill or traditional treadmill training group (P > 0.05). However, the difference between groups after training in COP maximum sway in medial-lateral direction during the quiet stance was significant (P = 0.038). Traditional treadmill training failed to improve sit-to-stand performance, whereas VR treadmill training improved symmetric index (P = 0.028) and sway excursion (P = 0.046) significantly during sit-to-stand transfer. The changes of symmetric index between groups were markedly different (P = 0.045). Finally, both groups improved significantly in stance time/P, but only VR treadmill training increased contact A/P (P = 0.034) after training during level walking. The difference between groups during level walking was not significant. Neither traditional treadmill nor VR treadmill training had any effect on balance skill during quiet stance, but VR treadmill training improved balance skill in the medial-lateral direction better than traditional training did. VR treadmill training also improved balance skill during sit-to-stand transfers and the involvement of paretic limb in level walking more than the traditional one did.

  19. Epaxial muscle fiber architecture favors enhanced excursion and power in the leaper Galago senegalensis

    PubMed Central

    Huq, Emranul; Wall, Christine E; Taylor, Andrea B

    2015-01-01

    Galago senegalensis is a habitual arboreal leaper that engages in rapid spinal extension during push-off. Large muscle excursions and high contraction velocities are important components of leaping, and experimental studies indicate that during leaping by G. senegalensis, peak power is facilitated by elastic storage of energy. To date, however, little is known about the functional relationship between epaxial muscle fiber architecture and locomotion in leaping primates. Here, fiber architecture of select epaxial muscles is compared between G. senegalensis (n = 4) and the slow arboreal quadruped, Nycticebus coucang (n = 4). The hypothesis is tested that G. senegalensis exhibits architectural features of the epaxial muscles that facilitate rapid and powerful spinal extension during the take-off phase of leaping. As predicted, G. senegalensis epaxial muscles have relatively longer, less pinnate fibers and higher ratios of tendon length-to-fiber length, indicating the capacity for generating relatively larger muscle excursions, higher whole-muscle contraction velocities, and a greater capacity for elastic energy storage. Thus, the relatively longer fibers and higher tendon length-to-fiber length ratios can be functionally linked to leaping performance in G. senegalensis. It is further predicted that G. senegalensis epaxial muscles have relatively smaller physiological cross-sectional areas (PCSAs) as a consequence of an architectural trade-off between fiber length (excursion) and PCSA (force). Contrary to this prediction, there are no species differences in relative PCSAs, but the smaller-bodied G. senegalensis trends towards relatively larger epaxial muscle mass. These findings suggest that relative increase in muscle mass in G. senegalensis is largely attributable to longer fibers. The relative increase in erector spinae muscle mass may facilitate sagittal flexibility during leaping. The similarity between species in relative PCSAs provides empirical support for previous work linking osteological features of the vertebral column in lorisids with axial stability and reduced muscular effort associated with slow, deliberate movements during anti-pronograde locomotion. PMID:26184388

  20. Cosmogenic 10Be signature of geomagnetic dipole moment variations over the last 2 Ma

    NASA Astrophysics Data System (ADS)

    Simon, Q.; Thouveny, N.; Bourlès, D. L.; Valet, J. P.; Bassinot, F. C.; Savranskaia, T.; Duvivier, A.; Choy, S.; Gacem, L.; Villedieu, A.

    2017-12-01

    Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Authigenic 10Be/9Be ratios (Be-ratio, proxy of atmospheric 10Be production) from marine sedimentary cores give independent and additional insights on the evolution of the geomagnetic intensity, completing information from absolute and relative paleointensity (RPI) records. Here we present new Be-ratio results obtained on several marine cores from the North Atlantic, Indian and Pacific Oceans which permit to extent into the Matuyama chron our previous 10Be-derived GDM reconstructions (Simon et al., 2016 JGR 121). Stratigraphic offsets measured between Be-ratio peaks and the corresponding RPI minima in each studied cores are assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 0 to 16 cm (up to 12 ka). All these results were compiled in order to obtain a continuous Be-ratio record covering the last 2 Ma. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Be-ratio stack (BeDiMo2Ma) was calibrated using absolute paleointensity data. This independent record completes the available paleomagnetic RPI records and permits: 1) to confront and increase the robustness and precision of GDM reconstructions; and, 2) to better constrain geomagnetic field instabilities during the mid- to late- Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to polarity reversals (Matuyama-Brunhes transition, Jaramillo and Olduvai boundaries), geomagnetic events (Cobb Mountain, Réunion) and Brunhes' excursions (e.g. Laschamp, Blake, Iceland-Basin, Big Lost). It further strengthens the occurrence of several Matuyama's excursions (Kamikatsura, Santa Rosa, Punaruu, Bjorn, Gilsa, Gardar) that were reported only from sparse locations.

  1. Cosmogenic signature of geomagnetic reversals and excursions from the Réunion event to the Matuyama-Brunhes transition (0.7-2.14 Ma interval)

    NASA Astrophysics Data System (ADS)

    Simon, Quentin; Bourlès, Didier L.; Thouveny, Nicolas; Horng, Chorng-Shern; Valet, Jean-Pierre; Bassinot, Franck; Choy, Sandrine

    2018-01-01

    Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Following several studies dealing with the Brunhes chron and the Matuyama-Brunhes transition, this study presents a new authigenic 10Be/9Be ratio (Be-ratio) record obtained from the MD97-2143 core (western Pacific Ocean). This new Be-ratio series yields a record of GDM variations covering the early Brunhes and mid to late Matuyama time period (i.e. 700-2140 ka), independently from the relative paleointensity (RPI) record obtained from the same core, that can be compared with available RPI records and stacks. Stratigraphic offsets measured between the Be-ratio peaks and the corresponding RPI minima reach 2 to 14 cm. They can be assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 2 to 12 ka in the studied core. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Beryllium-10 (BeDiMo) was compiled and calibrated using absolute paleointensity data. This independent record complements the available paleomagnetic RPI records, permitting 1) to overcome the pDRM lock-in offsets induced below the mixing layer, 2) to confront and increase the robustness and precision of GDM reconstructions and, 3) to better constrain the chronology of geomagnetic field instabilities during the mid to late Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to geomagnetic polarity reversals and events (Matuyama-Brunhes transition, Jaramillo and Olduvai subchron boundaries, Cobb Mountain, Réunion) and it strengthens the occurrence of several excursions (Kamikatsura, Santa Rosa, Punaruu, Bjorn, Gilsa, Gardar) that were until now reported from only sparse locations.

  2. Occupant kinematics of the Hybrid III, THOR-M, and postmortem human surrogates under various restraint conditions in full-scale frontal sled tests.

    PubMed

    Albert, Devon L; Beeman, Stephanie M; Kemper, Andrew R

    2018-02-28

    The objective of this research was to compare the occupant kinematics of the Hybrid III (HIII), THOR-M, and postmortem human surrogates (PMHS) during full-scale frontal sled tests under 3 safety restraint conditions: knee bolster (KB), knee bolster and steering wheel airbag (KB/SWAB), and knee bolster airbag and steering wheel airbag (KBAB/SWAB). A total of 20 frontal sled tests were performed with at least 2 tests performed per restraint condition per surrogate. The tests were designed to match the 2012 Toyota Camry New Car Assessment Program (NCAP) full-scale crash test. Rigid polyurethane foam surrogates with compressive strength ratings of 65 and 19 psi were used to simulate the KB and KBAB, respectively. The excursions of the head, shoulders, hips, knees, and ankles were collected using motion capture. Linear acceleration and angular velocity data were also collected from the head, thorax, and pelvis of each surrogate. Time histories were compared between surrogates and restraint conditions using ISO/TS 18571. All surrogates showed some degree of sensitivity to changes in restraint condition. For example, the use of a KBAB decreased the pelvis accelerations and the forward excursions of the knees and hips for all surrogates. However, these trends were not observed for the thorax, shoulders, and head, which showed more sensitivity to the presence of a SWAB. The average scores computed using ISO/TS 18571 for the HIII/PMHS and THOR-M/PMHS comparisons were 0.527 and 0.518, respectively. The HIII had slightly higher scores than the THOR-M for the excursions (HIII average = 0.574; THOR average = 0.520). However, the THOR-M had slightly higher scores for the accelerations and angular rates (HIII average = 0.471; THOR average = 0.516). The data from the current study showed that both KBABs and SWABs affected the kinematics of all surrogates during frontal sled tests. The results of the objective rating analysis indicated that the HIII and THOR-M had comparable overall biofidelity scores. The THOR-M slightly outperformed the HIII for the acceleration and angular velocity data. However, the HIII scored slightly better than the THOR-M for the excursion data. The most notable difference in biofidelity was for the knee excursions, where the HIII had a much higher average ISO score. Only the biofidelity of the HIII and THOR-M with regard to occupant kinematics was evaluated in this study; therefore, future work will evaluate the biofidelity of the ATDs in terms of lower extremity loading, thoracic response, and neck loading.

  3. The Late Eocene 187Os / 188Os excursion: Chemostratigraphy, cosmic dust flux and the Early Oligocene glaciation

    NASA Astrophysics Data System (ADS)

    Dalai, Tarun K.; Ravizza, Gregory E.; Peucker-Ehrenbrink, B.

    2006-01-01

    High resolution records (ca. 100 kyr) of Os isotope composition ( 187Os / 188Os) in bulk sediments from two tropical Pacific sites (ODP Sites 1218 and 1219) capture the complete Late Eocene 187Os / 188Os excursion and confirm that the Late Eocene 187Os / 188Os minimum, earlier reported by Ravizza and Peucker-Ehrenbrink [Earth Planet. Sci. Lett. 210 (2003) 151-165], is a global feature. Using the astronomically tuned age models available for these sites, it is suggested that the Late Eocene 187Os / 188Os minimum can be placed at 34.5 ± 0.1 Ma in the marine records. In addition, two other distinct features of the 187Os / 188Os excursion that are correlatable among sections are proposed as chemostratigraphic markers which can serve as age control points with a precision of ca. ± 0.1 Myr. We propose a speculative hypothesis that higher cosmic dust flux in the Late Eocene may have contributed to global cooling and Early Oligocene glaciation (Oi-1) by supplying bio-essential trace elements to the oceans and thereby resulting in higher ocean productivity, enhanced burial of organic carbon and draw down of atmospheric CO 2. To determine if the hypothesis that enhanced cosmic dust flux in the Late Eocene was a cause for the 187Os / 188Os excursion can be tested by using the paired bulk sediment and leachate Os isotope composition; 187Os / 188Os were also measured in sediment leachates. Results of analyses of leachates are inconsistent between the south Atlantic and the Pacific sites, and therefore do not yield a robust test of this hypothesis. Comparison of 187Os / 188Os records with high resolution benthic foraminiferal δ18O records across the Eocene-Oligocene transition suggests that 187Os flux to the oceans decreased during cooling and ice growth leading to the Oi-1 glaciation, whereas subsequent decay of ice-sheets and deglacial weathering drove seawater 187Os / 188Os to higher values. Although the precise timing and magnitude of these changes in weathering fluxes and their effects on the marine 187Os / 188Os records are obscured by recovery from the Late Eocene 187Os / 188Os excursion, evidence of the global influence of glaciation on supply of Os to the ocean is robust as it has now been documented in both Pacific and Atlantic records.

  4. Beryllium isotopes as tracers of Lake Lisan (last Glacial Dead Sea) hydrology and the Laschamp geomagnetic excursion

    NASA Astrophysics Data System (ADS)

    Belmaker, Reuven; Stein, Mordechai; Beer, Jürg; Christl, Marcus; Fink, David; Lazar, Boaz

    2014-08-01

    The content of the cosmogenic isotope 10Be (t1/2=1.39 Ma) in lacustrine sediments that deposit in lakes with a large watershed is susceptible to both climate and cosmogenic production rate variations. In order to distinguish between these two controls, we measured 10Be and major elements in several sections of the annually laminated sediments of the Lake Lisan (the last Glacial precursor of the Dead Sea) that are composed of detrital sediments and primary (evaporitic) aragonites. The sections were selected to represent regional hydrology and climate as reflected by different lake configurations (level rise, drop and high-stands) and rapid change in the 10Be production rate during the Laschamp geomagnetic excursion. Since the short-lived cosmogenic “sister” of 10Be, 7Be (t1/2=53.3 d) has virtually no recycled component, the recycled 10Be in Lake Lisan detrital sediments was evaluated by measuring 7Be in their modern equivalents: modern flood suspended matter, dust and mud cracks. Our results demonstrate that although the recycled 10Be component is significant, secular variations in the 10Be concentration in Lake Lisan sediments correlate with hydrological variations and geomagnetic excursions. During periods of moderate variations in 10Be production rate, the 10Be concentration in the Lisan detrital sediments positively correlates with lake level, Al + Fe content and the (Al + Fe)/(Ca + Mg) ratio. These correlations suggest that the 10Be is adsorbed on the fine silicate component (probably clays) of the detrital laminae. The fine silicates together with carbonates were transported to Dead Sea drainage basin mainly as airborne dust that after a short residence time was washed into Lake Lisan as flood suspended matter. We suggest that preferential dissolution of carbonates in the flood suspended matter concentrated the residual fine component leading to the positive correlation between 10Be and the (Al + Fe)/(Ca + Mg) ratio. During periods of increased water discharge more carbonates were dissolved and hence the 10Be concentration in the detrital laminae increased. During periods of rapid increase in the 10Be production rate (e.g. the Laschamp excursion), 10Be showed a ∼2 fold increase, beyond the above-mentioned correlations (lake levels and Al + Fe contents). This observation suggests that Lake Lisan can serve as a potential high-resolution archive of 10Be production rate variations during periods of geomagnetic excursions.

  5. Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease.

    PubMed

    Mobbs, Charles V; Mastaitis, Jason W; Zhang, Minhua; Isoda, Fumiko; Cheng, Hui; Yen, Kelvin

    2007-01-01

    Elevated blood glucose associated with diabetes produces progressive and apparently irreversible damage to many cell types. Conversely, reduction of glucose extends life span in yeast, and dietary restriction reduces blood glucose. Therefore it has been hypothesized that cumulative toxic effects of glucose drive at least some aspects of the aging process and, conversely, that protective effects of dietary restriction are mediated by a reduction in exposure to glucose. The mechanisms mediating cumulative toxic effects of glucose are suggested by two general principles of metabolic processes, illustrated by the lac operon but also observed with glucose-induced gene expression. First, metabolites induce the machinery of their own metabolism. Second, induction of gene expression by metabolites can entail a form of molecular memory called hysteresis. When applied to glucose-regulated gene expression, these two principles suggest a mechanism whereby repetitive exposure to postprandial excursions of glucose leads to an age-related increase in glycolytic capacity (and reduction in beta-oxidation of free fatty acids), which in turn leads to an increased generation of oxidative damage and a decreased capacity to respond to oxidative damage, independent of metabolic rate. According to this mechanism, dietary restriction increases life span and reduces pathology by reducing exposure to glucose and therefore delaying the development of glucose-induced glycolytic capacity.

  6. Oxygenation of the shallow ocean after the Great Oxidation Event: Geochemistry and Carbon isotopes of the Paleoproterozoic Hutuo Group in North China Craton

    NASA Astrophysics Data System (ADS)

    She, Z.; Yang, F.; Papineau, D.

    2013-12-01

    The Paleoproterozoic was known as a period of profound perturbations in marine environments and biogeochemical cycles due to the Great Oxidation Event (GOE), but the interconnections and consequences of these events remain poorly understood. We investigated the geochemistry and C isotopes of the 2.09-1.96 Ga Hutuo Group in the North China Craton (NCC) which provide evidence for the oxygenation of shallow oceans. The Hutuo Group is a >10-km-thick clastic and carbonate sequence with intercalated basalts and has undergone lower greenschist facies metamorphism. Diverse stromatolite morphotypes, ranging from small domical, conical, and columnar forms to bioherms with diameters up to 4 meters, as well as giant oncoids, are developed in the Hutuo carbonates. C isotopes of the Hutuo carbonates are characterized by a general decrease in δ13Ccarb values upsection. It consists of a lower part with δ13Ccarb ranging from 1.3 ‰ to 3.4 ‰, a middle part showing alternating positive and negative excursions of δ13Ccarb from -3.6 ‰ to 2.7 ‰, and a upper part of exclusively negative excursions with δ13Ccarb as light as -5.6 ‰. Most samples have δ18Ocarb greater than -10 ‰ and show no correlation between δ18Ocarb and δ13Ccarb. This, along with relatively low Mn/Sr ratios (mostly < 10), exclude significant diagenetic modification of the C isotopes. δ13Corg of acid-insoluble residues of stromatolitic carbonates range between -30.9 ‰ and -22.3 ‰, consistent with C-fixation with the cyanobacterial RuBisCO enzymes. Therefore, the positive excursions are probably related to burial of organic matter produced by primary producers, consistent with the ending of the 2.22-2.06 Ga Lomagundi-Jatuli event. Similar positive C isotope excursions have also been reported from contemporaneous successions elsewhere in the NCC, including the Songshan Group in Henan and Liaohe Group in Liaoning. The following negative excursions, which is consistent with the excursions reported from the 2.1-2.0 Ga Zaonega Fm in the Fennoscandian Shield, thus correspond to pulsed oxidation of biomass in an oxygenated shallow ocean. The geochemical signatures of the carbonates which show minimal contamination by terrigenous materials provides constrains on the chemistry of the Paleoproterozoic ocean. PAAS-normalized REE patterns are flat or slightly LREE-depleted with variable but slightly negative to positive shale-normalized Ce anomaly and evident Eu anomaly. The carbonates have low concentrations of U, Mo, Co and Ni, and show upsection decrease in Mo, Co and Ni abundances, consistent with increasing redox states. Metapelites from the Hutuo Group show slightly positive Eu anomaly and low Mo concentrations and U/Th ratios (0.33 - 0.10), consistent with deposition in an oxygenated environment. Collectively, the data document the fluctuations of ocean redox states and final oxygenation of the Hutuo Basin in the aftermath of the GOE. Blooms of stromatolite-building cyanobacteria caused by high nutrient availability following the GOE might have played key roles in the final oxygenation of the atmosphere and shallow oceans.

  7. Carbon isotope chemostratigraphy and precise dating of middle Frasnian (lower Upper Devonian) Alamo Breccia, Nevada, USA

    USGS Publications Warehouse

    Morrow, J.R.; Sandberg, C.A.; Malkowski, K.; Joachimski, M.M.

    2009-01-01

    At Hancock Summit West, Nevada, western USA, uppermost Givetian (upper Middle Devonian) and lower and middle Frasnian (lower Upper Devonian) rocks of the lower Guilmette Formation include, in stratigraphic sequence, carbonate-platform facies of the conodont falsiovalis, transitans, and punctata Zones; the type Alamo Breccia Member of the middle punctata Zone; and slope facies of the punctata and hassi Zones. The catastrophically deposited Alamo Breccia and related phenomena record the ~ 382??Ma Alamo event, produced by a km-scale bolide impact into a marine setting seaward of an extensive carbonate platform fringing western North America. Re-evaluation of conodonts from the lower Guilmette Formation and Alamo Breccia Member, together with regional sedimentologic and conodont biofacies comparisons, now firmly locates the onset of the Johnson et al. (1985) transgressive-regressive (T-R) cycle IIc, which occurred after the start of the punctata Zone, within a parautochthonous megablock low in the Alamo Breccia. Whole-rock carbon isotope analyses through the lower Guilmette Formation and Alamo Breccia Member reveal two positive ??13Ccarb excursions: (1) a small, 3??? excursion, which is possibly correlative with the falsiovalis Event previously identified from sections in Western Europe and Australia, occurs below the breccia in the Upper falsiovalis Zone to early part of the transitans Zone; and (2) a large, multi-part excursion, dominated by a 6??? positive shift, begins above the start of the punctata Zone and onset of T-R cycle IIc and continues above the Alamo Breccia, ending near the punctata- hassi zonal boundary. This large excursion correlates with the punctata Event, a major positive ??13C excursion previously recognized in eastern Laurussia and northern Gondwana. Consistent with previous studies, at Hancock Summit West the punctata Event is apparently not associated with any regional extinctions or ecosystem reorganizations. In the study area, onset of the main punctata Event began after the start of both the punctata Zone and T-R cycle IIc, and preceded the Alamo impact by less than 650??k.y., as inferred from conodont biochronologic and regional rock-accumulation rate estimates. Although complicated by the heterolithic, high-energy deposits of the Alamo Breccia, the carbon isotope record of the breccia and post-breccia beds does not indicate a major impact-correlative perturbation to the carbon cycle. This study extends recognition of the punctata Event to western Laurussia, further reinforcing the potential global scale of the event and its potential importance to understanding early to middle Frasnian marine geochemistry and palaeoenvironments. Based on previous models and our observations, increased tectonic activity, increased nutrient flux to oceans, increased marine bioproductivity, widespread anoxia, and increased organic carbon burial were all likely key factors in driving the punctata Event excursion. Furthermore, periodic eustatic and regional relative sea-level rises may have played an important role in promoting organic carbon burial and in maintaining a link between the primary open-marine geochemical signal and that recorded on the shallow-marine, lower Guilmette carbonate platform. ?? 2009 Elsevier B.V. All rights reserved.

  8. Influence of intramuscular fiber orientation on the Achilles tendon curvature using three-dimensional finite element modeling of contracting skeletal muscle.

    PubMed

    Kinugasa, Ryuta; Yamamura, Naoto; Sinha, Shantanu; Takagi, Shu

    2016-10-03

    Tendon curvature plays a key role in mechanical gain (amplifying the joint excursion relative to fiber length change) during joint motion, but the mechanism remains unresolved. A three-dimensional finite element (FE) model was used to investigate the influence of intramuscular fiber orientation upon the curvature pattern of the Achilles tendon during active muscular contraction. Two simulation models, with fiber pennation angles of θ = 25° and 47° were tested for the gastrocnemius and soleus muscles. A smaller pennation angle (25°) of the soleus muscle fibers was accompanied by a large change in curvature whereas a larger pennation angle (47°) of the soleus muscle was accompanied by small effects. These results suggest that the fiber pennation angle determines the curvature of the tendon, and the magnitude of the curvature varies along the length of the aponeurosis. Such FE modeling has the potential of determining changes in force output consequent to changes in intramuscular fiber orientation arising from resistance training or unloading, and provides mechanism for predicting the risk of Achilles tendon ruptures. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Developing A New Predictive Dispersion Equation Based on Tidal Average (TA) Condition in Alluvial Estuaries

    NASA Astrophysics Data System (ADS)

    Anak Gisen, Jacqueline Isabella; Nijzink, Remko C.; Savenije, Hubert H. G.

    2014-05-01

    Dispersion mathematical representation of tidal mixing between sea water and fresh water in The definition of dispersion somehow remains unclear as it is not directly measurable. The role of dispersion is only meaningful if it is related to the appropriate temporal and spatial scale of mixing, which are identified as the tidal period, tidal excursion (longitudinal), width of estuary (lateral) and mixing depth (vertical). Moreover, the mixing pattern determines the salt intrusion length in an estuary. If a physically based description of the dispersion is defined, this would allow the analytical solution of the salt intrusion problem. The objective of this study is to develop a predictive equation for estimating the dispersion coefficient at tidal average (TA) condition, which can be applied in the salt intrusion model to predict the salinity profile for any estuary during different events. Utilizing available data of 72 measurements in 27 estuaries (including 6 recently studied estuaries in Malaysia), regressions analysis has been performed with various combinations of dimensionless parameters . The predictive dispersion equations have been developed for two different locations, at the mouth D0TA and at the inflection point D1TA (where the convergence length changes). Regressions have been carried out with two separated datasets: 1) more reliable data for calibration; and 2) less reliable data for validation. The combination of dimensionless ratios that give the best performance is selected as the final outcome which indicates that the dispersion coefficient is depending on the tidal excursion, tidal range, tidal velocity amplitude, friction and the Richardson Number. A limitation of the newly developed equation is that the friction is generally unknown. In order to compensate this problem, further analysis has been performed adopting the hydraulic model of Cai et. al. (2012) to estimate the friction and depth. Keywords: dispersion, alluvial estuaries, mixing, salt intrusion, predictive equation

  10. Design of a probe for two-dimensional small angle detection

    NASA Astrophysics Data System (ADS)

    He, Haixia; Wang, Xuanze; Zhong, Yuning; Yang, Liangen; Cao, Hongduan

    2008-10-01

    A novel two-dimensional small angle probe is introduced, which is based on principle of auto-collimation and utilizes quadrant Si-photoelectric detector (QPD) as detection device. AC modulation, AC magnification and absolute value demodulation are incorporated to restrain the DC excursion caused by background light and noise etc and to improve the sensitivity and stability of angle detection. To ensure that while the laser is shining, the current signal (converted into voltage signal) of QPD also is linear to the AC modulation voltage, this paper adopted AC modulation signal (5400Hz) with a DC offset. AC magnification circuit with reasonable parameters is designed to inhibit DC drift and the impact of industrial frequency noise and to ensure good amplification to signal frequency at the same time. A piezoelectric-driven micro-angle generator is designed to demarcate the angle. The calibration data are input to single chip, and the measurement of angles can be shown in SMC1602A.

  11. Limited Influence of Urban Stormwater Runoff on Salt Marsh Platform and Marsh Creek Oxygen Dynamics in Coastal Georgia.

    PubMed

    Savidge, William B; Brink, Jonathan; Blanton, Jackson O

    2016-12-01

    Oxygen concentrations and oxygen utilization rates were monitored continuously for 23 months on marsh platforms and in small tidal creeks at two sites in coastal Georgia, USA, that receive urban stormwater runoff via an extensive network of drainage canals. These data were compared to nearby control sites that receive no significant surface runoff. Overall, rainfall and runoff per se were not associated with differences in the oxygen dynamics among the different locations. Because of the large tidal range and long tidal excursions in coastal Georgia, localized inputs of stormwater runoff are rapidly mixed with large volumes of ambient water. Oxygen concentrations in tidal creeks and on flooded marsh platforms were driven primarily by balances of respiration and photosynthesis in the surrounding regional network of marshes and open estuarine waters. Local respiration, while measurable, was of relatively minor importance in determining oxygen concentrations in tidal floodwaters. Water residence time on the marshes could explain differences in oxygen concentration between the runoff-influenced and control sites.

  12. Limited Influence of Urban Stormwater Runoff on Salt Marsh Platform and Marsh Creek Oxygen Dynamics in Coastal Georgia

    NASA Astrophysics Data System (ADS)

    Savidge, William B.; Brink, Jonathan; Blanton, Jackson O.

    2016-12-01

    Oxygen concentrations and oxygen utilization rates were monitored continuously for 23 months on marsh platforms and in small tidal creeks at two sites in coastal Georgia, USA, that receive urban stormwater runoff via an extensive network of drainage canals. These data were compared to nearby control sites that receive no significant surface runoff. Overall, rainfall and runoff per se were not associated with differences in the oxygen dynamics among the different locations. Because of the large tidal range and long tidal excursions in coastal Georgia, localized inputs of stormwater runoff are rapidly mixed with large volumes of ambient water. Oxygen concentrations in tidal creeks and on flooded marsh platforms were driven primarily by balances of respiration and photosynthesis in the surrounding regional network of marshes and open estuarine waters. Local respiration, while measurable, was of relatively minor importance in determining oxygen concentrations in tidal floodwaters. Water residence time on the marshes could explain differences in oxygen concentration between the runoff-influenced and control sites.

  13. SSME turbopump bearing analytical study

    NASA Technical Reports Server (NTRS)

    Kannel, J. W.; Merriman, T.

    1980-01-01

    Three shuttle pump bearings operating under severe overspeed and shut-down conditions are evaluated. The specific parameters investigated include outer race stresses, cage stresses, cage-race drag, bearing heating, and crush loading. A quasi-dynamic version of the BASDAP computer code was utilized which involved the calculation of ball-race forces (inner and outer), contact pressures, contact dimensions, and contact angles as a function of (1) axial load, (2) radial load, and (3) centrifugal load on the bearing. Generally, radial loads on the order of 13,300 N (3000 pounds) per bearing or 26,700 N (6000 pounds) per bearing pair, could be expected to cause severe problems to any of the bearings with a 17,800 N (4000 pounds) axial load. Further, when possible temperature excursions are considered, even a load of 8900 N (2000 pounds) may be excessive. However, high momentary radial loads with a 3800 N (850 pounds) axial load would not be anticipated to cause catastrophic failure of the fuel pump bearing.

  14. A benchtop biorobotic platform for in vitro observation of muscle-tendon dynamics with parallel mechanical assistance from an elastic exoskeleton.

    PubMed

    Robertson, Benjamin D; Vadakkeveedu, Siddarth; Sawicki, Gregory S

    2017-05-24

    We present a novel biorobotic framework comprised of a biological muscle-tendon unit (MTU) mechanically coupled to a feedback controlled robotic environment simulation that mimics in vivo inertial/gravitational loading and mechanical assistance from a parallel elastic exoskeleton. Using this system, we applied select combinations of biological muscle activation (modulated with rate-coded direct neural stimulation) and parallel elastic assistance (applied via closed-loop mechanical environment simulation) hypothesized to mimic human behavior based on previously published modeling studies. These conditions resulted in constant system-level force-length dynamics (i.e., stiffness), reduced biological loads, increased muscle excursion, and constant muscle average positive power output-all consistent with laboratory experiments on intact humans during exoskeleton assisted hopping. Mechanical assistance led to reduced estimated metabolic cost and MTU apparent efficiency, but increased apparent efficiency for the MTU+Exo system as a whole. Findings from this study suggest that the increased natural resonant frequency of the artificially stiffened MTU+Exo system, along with invariant movement frequencies, may underlie observed limits on the benefits of exoskeleton assistance. Our novel approach demonstrates that it is possible to capture the salient features of human locomotion with exoskeleton assistance in an isolated muscle-tendon preparation, and introduces a powerful new tool for detailed, direct examination of how assistive devices affect muscle-level neuromechanics and energetics. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Laterally Translating Seal Carrier For A Drilling Mud Motor Sealed Bearing Assembly

    DOEpatents

    Dietle, Lannie

    1993-03-23

    A sealing and lubrication assembly for rotating shafts intended for operation in an abrasive environment and wherein the rotary shaft may have lateral translation or excursion during its rotation. A housing receives the rotary shaft in bearing supporting relation and defines a lubricant chamber about the shaft. A seal carrier is movably positioned about the rotary shaft and has non-rotatable articulating or laterally translating relation with the housing. A high pressure rotary shaft seal is supported by the seal carrier and maintains bearing and sealing engagement with the rotary shaft during its lateral translation or excursion. The seal carrier is hydraulic force balanced and thus is not subject to pressure induced loads that might otherwise interfere with its articulation or lateral translation.

  16. Spiral Transformation for High-Resolution and Efficient Sorting of Optical Vortex Modes.

    PubMed

    Wen, Yuanhui; Chremmos, Ioannis; Chen, Yujie; Zhu, Jiangbo; Zhang, Yanfeng; Yu, Siyuan

    2018-05-11

    Mode sorting is an essential function for optical multiplexing systems that exploit the orthogonality of the orbital angular momentum mode space. The familiar log-polar optical transformation provides a simple yet efficient approach whose resolution is, however, restricted by a considerable overlap between adjacent modes resulting from the limited excursion of the phase along a complete circle around the optical vortex axis. We propose and experimentally verify a new optical transformation that maps spirals (instead of concentric circles) to parallel lines. As the phase excursion along a spiral in the wave front of an optical vortex is theoretically unlimited, this new optical transformation can separate orbital angular momentum modes with superior resolution while maintaining unity efficiency.

  17. Work Capability and physiological effects predictive studies. 4: In He-O2 excursions to pressures of 400- 800- 1200- and 1600 feet of sea water

    NASA Technical Reports Server (NTRS)

    Lambertsen, C. J. (Editor); Gelfand, R. (Editor); Clark, J. M. (Editor); Fletcher, M. E. (Editor)

    1978-01-01

    Experiments which exposed men in chambers, breathing helium with oxygen, to progressive increases of pressure equivalent to 400-800-1200-1600 feet of sea water (fsw) were conducted. Rates of compression and exposure to stable high pressure. Goals included: 1) determination of the specific character and time course of onset of physiological and performance decrements during the intentionally rapid compressions, and determination of rates of adaptation on reaching stable elevated pressure; 2) investigation of accelerated methods for decompression in deep saturation excursion diving; and 3) determination of competence in practical work performed in water at pressures equivalent to the extreme diving depths of 1200 and 1600 fsw.

  18. The Neutral Islands during the Late Epoch of Reionization

    NASA Astrophysics Data System (ADS)

    Xu, Yidong; Yue, Bin; Chen, Xuelei

    2018-05-01

    The large-scale structure of the ionization field during the epoch of reionization (EoR) can be modeled by the excursion set theory. While the growth of ionized regions during the early stage are described by the ``bubble model'', the shrinking process of neutral regions after the percolation of the ionized region calls for an ``island model''. An excursion set based analytical model and a semi-numerical code (islandFAST) have been developed. The ionizing background and the bubbles inside the islands are also included in the treatment. With two kinds of absorbers of ionizing photons, i.e. the large-scale under-dense neutral islands and the small-scale over-dense clumps, the ionizing background are self-consistently evolved in the model.

  19. Spiral Transformation for High-Resolution and Efficient Sorting of Optical Vortex Modes

    NASA Astrophysics Data System (ADS)

    Wen, Yuanhui; Chremmos, Ioannis; Chen, Yujie; Zhu, Jiangbo; Zhang, Yanfeng; Yu, Siyuan

    2018-05-01

    Mode sorting is an essential function for optical multiplexing systems that exploit the orthogonality of the orbital angular momentum mode space. The familiar log-polar optical transformation provides a simple yet efficient approach whose resolution is, however, restricted by a considerable overlap between adjacent modes resulting from the limited excursion of the phase along a complete circle around the optical vortex axis. We propose and experimentally verify a new optical transformation that maps spirals (instead of concentric circles) to parallel lines. As the phase excursion along a spiral in the wave front of an optical vortex is theoretically unlimited, this new optical transformation can separate orbital angular momentum modes with superior resolution while maintaining unity efficiency.

  20. Validation of the Inverted Pendulum Model in standing for transtibial prosthesis users.

    PubMed

    Rusaw, David F; Ramstrand, Simon

    2016-01-01

    Often in balance assessment variables associated with the center of pressure are used to draw conclusions about an individual's balance. Validity of these conclusions rests upon assumptions that movement of the center of pressure is inter-dependent on movement of the center of mass. This dependency is mechanical and is referred to as the Inverted Pendulum Model. The following study aimed to validate this model both kinematically and kinetically, in transtibial prosthesis users and a control group. Prosthesis users (n=6) and matched control participants (n=6) stood quietly while force and motion data were collected under three conditions (eyes-open, eyes-closed, and weight-bearing feedback). Correlation coefficients were used to investigate the relationships between height and excursion of markers and center of masses in mediolateral/anteroposterior-directions, difference between center of pressure and center of mass and the center of mass acceleration in mediolateral/anteroposterior directions, magnitude of mediolateral/anteroposterior-component forces and center of mass acceleration, angular position of ankle and excursion in mediolateral/anteroposterior-directions, and integrated force signals. Results indicate kinematic validity of similar magnitudes (mean (SD) marker-displacement) between prosthesis users and control group for mediolateral- (r=0.77 (0.17); 0.74 (0.19)) and anteroposterior-directions (r=0.88 (0.18); 0.88 (0.19)). Correlation between difference of center of pressure and center of mass and the center of mass acceleration was negligible on the prosthetic side (r = 0.08 (0.06)) vs. control group (r=-0.51(0.13)). Results indicate kinematic validity of the Inverted Pendulum Model in transtibial prosthesis users but kinetic validity is questionable, particularly on the side with a prosthesis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Spatial and temporal patterns of subtidal and intertidal crabs excursions

    NASA Astrophysics Data System (ADS)

    Silva, A. C. F.; Boaventura, D. M.; Thompson, R. C.; Hawkins, S. J.

    2014-01-01

    Highly mobile predators such as fish and crabs are known to migrate from the subtidal zone to forage in the intertidal zone at high-tide. The extent and variation of these habitat linking movements along the vertical shore gradient have not been examined before for several species simultaneously, hence not accounting for species interactions. Here, the foraging excursions of Carcinus maenas (L.), Necora puber (Linnaeus, 1767) and Cancer pagurus (Linnaeus, 1758) were assessed in a one-year mark-recapture study on two replicated rocky shores in southwest U.K. A comparison between the abundance of individuals present on the shore at high-tide with those present in refuges exposed at low-tide indicated considerable intertidal migration by all species, showing strong linkage between subtidal and intertidal habitats. Estimates of population size based on recapture of marked individuals indicated that an average of ~ 4000 individuals combined for the three crab species, can be present on the shore during one tidal cycle. There was also a high fidelity of individuals and species to particular shore levels. Underlying mechanisms for these spatial patterns such as prey availability and agonistic interactions are discussed. Survival rates were estimated using the Cormack-Jolly-Seber model from multi-recapture analysis and found to be considerably high with a minimum of 30% for all species. Growth rates were found to vary intraspecifically with size and between seasons. Understanding the temporal and spatial variations in predation pressure by crabs on rocky shores is dependent on knowing who, when and how many of these commercially important crab species depend on intertidal foraging. Previous studies have shown that the diet of these species is strongly based on intertidal prey including key species such as limpets; hence intertidal crab migration could be associated with considerable impacts on intertidal assemblages.

  2. Diaphragm and Lung Ultrasound to Predict Weaning Outcome: Systematic Review and Meta-Analysis.

    PubMed

    Llamas-Álvarez, Ana M; Tenza-Lozano, Eva M; Latour-Pérez, Jaime

    2017-12-01

    Deciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not very accurate. The aim of this systematic review and meta-analysis was to assess the accuracy of lung and diaphragm ultrasound for predicting weaning outcomes in critically ill adults. MEDLINE, the Cochrane Library, Web of Science, Scopus, LILACS, Teseo, Tesis Doctorales en Red, and OpenGrey were searched, and the bibliographies of relevant studies were reviewed. Two researchers independently selected studies that met the inclusion criteria and assessed study quality in accordance with the Quality Assessment of Diagnostic Accuracy Studies-2 tool. The summary receiver-operating characteristic curve and pooled diagnostic OR (DOR) were estimated by using a bivariate random effects analysis. Sources of heterogeneity were explored by using predefined subgroup analyses and bivariate meta-regression. Nineteen studies involving 1,071 people were included in the study. For diaphragm thickening fraction, the area under the summary receiver-operating characteristic curve was 0.87, and DOR was 21 (95% CI, 11-40). Regarding diaphragmatic excursion, pooled sensitivity was 75% (95% CI, 65-85); pooled specificity, 75% (95% CI, 60-85); and DOR, 10 (95% CI, 4-24). For lung ultrasound, the area under the summary receiver-operating characteristic curve was 0.77, and DOR was 38 (95% CI, 7-198). Based on bivariate meta-regression analysis, a significantly higher specificity for diaphragm thickening fraction and higher sensitivity for diaphragmatic excursion was detected in studies with applicability concerns. Lung and diaphragm ultrasound can help predict weaning outcome, but its accuracy may vary depending on the patient subpopulation. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

  3. Uncovering deep mysteries: the underwater life of an amphibious louse.

    PubMed

    Leonardi, Maria Soledad; Aznar, F Javier; Crespo, Enrique A; Lazzari, Claudio R

    2014-12-01

    Despite the incredible success of insects in colonizing almost every habitat, they remain virtually absent in one major environment--the open sea. A variety of hypotheses have been raised to explain why just a few insect species are present in the ocean, but none of them appears to be fully explanatory. Lice belonging to the family Echinophthiriidae are ectoparasites on different species of pinnipeds and river otters, i.e. they have amphibious hosts, who regularly perform long excursions into the open sea reaching depths of hundreds of meters (thousands of feets). Consequently, lice must be able to support not only changes in their surrounding media, but also extreme variations in hydrostatic pressure as well as breathing in a low oxygen atmosphere. In order to shed some light on the way lice can survive during the diving excursions of their hosts, we have performed a series of experiments to test the survival capability of different instars of Antarctophthirus microchir (Phthiraptera: Anoplura) from South American sea lions Otaria flavescens, when submerged into seawater. These experiments were aimed at analyzing: (a) immersion tolerance along the louse life; (b) lice's ability to obtain oxygen from seawater; (c) physiological responses and mechanisms involved in survival underwater. Our experiments showed that the forms present in non-diving pups--i.e. eggs and first-instar nymphs--were unable to tolerate immersion in water, while following instars and adults, all usually found in diving hosts, supported it very well. Furthermore, as long as the level of oxygen dissolved in water was higher, the lice survival capability underwater increased, and the recovery period after returning to air declined. These results are discussed in relation to host ecology, host exploitation and lice functional morphology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Carbon isotope evidence for a vigorous biological pump in the wake of end-Permian mass extinction

    NASA Astrophysics Data System (ADS)

    Meyer, K. M.; Yu, M.; Jost, A. B.; Payne, J.

    2009-12-01

    Ocean anoxia and euxinia have long been linked to the end-Permian mass extinction and the subsequent Early Triassic interval of delayed biotic recovery. This anoxic, sulfidic episode has been ascribed to both low- and high-productivity states in the marine water column, leaving the causes of euxinia and the mechanisms underlying delayed recovery poorly understood. To examine the nature of the end-Permian and Early Triassic biological production, we measured the carbon isotopic composition of carbonates from an exceptionally preserved carbonate platform in the Nanpanjiang Basin of south China. 13C of limestones from 5 stratigraphic sections displays a gradient of approximately 4‰ from shallow to deep water within the Lower Triassic. The limestones are systematically enriched in the platform interior relative to coeval slope and basin margin deposits by 2-4‰ at the peaks of correlative positive and negative δ13C excursions. This gradient subsequently collapses to less than 1‰ in the Middle Triassic, coincident with accelerated biotic recovery and cessation of δ13C excursions. Based on the relationship between δ18O and δ13C, trace metal analyses, and lithostratigraphic context, we conclude that the carbon isotope gradient is unlikely to reflect meteoric diagenesis, organic matter remineralization, or changes in the mixing ratio of sediment sources and minerals across the platform. Instead, we interpret the relatively depleted δ13C values toward the basin as reflecting DIC input from 13C-depleted deep waters during early diagenesis in a nutrient-rich, euxinic ocean. These observations suggest that a vigorous prokaryote-driven biological pump sustained Early Triassic ocean anoxia and inhibited recovery of animal ecosystems.

  5. Recovery collapse coincident with ongoing carbon cycle perturbations following the Permian-Triassic mass extinction

    NASA Astrophysics Data System (ADS)

    Petsios, E.; Bottjer, D. J.

    2016-12-01

    The Permian-Triassic mass extinction, the largest extinction of the Phanerozoic, is attributed to volcanic outgassing from the Siberian Traps and the resulting climate change. Ongoing volcanism in the Early Triassic is implicated for continued carbon cycle instability following the initial event, reflected in large inorganic carbon isotope excursions throughout the 5 Mya interval. Recent paleoecological studies have shown that timing of recovery from the extinction in the Early Triassic is highly complex, differing between regions, with documented cases of "early" recovery in some environments. The importance of specific environmental factors, such as oxygen levels and sea surface temperatures, in aiding or hindering recovery following the extinction is the topic of ongoing study. Here we present an ecological survey of marine benthic communities from the Lower Triassic Blacktail Creek outcrop of the Dinwoody Formation, correlated bed-for-bed with inorganic carbon isotope values. We observe incipient recovery as communities show increasing richness and evenness throughout the section, followed by a `collapse' with a return of high dominance, low richness fauna coincident with large δ13Ccarb shifts. We observe a statistically significant correlation between the magnitude of δ13Ccarb excursions and benthic community complexity over a stratigraphic section, implying a shared causal mechanism acting at the local scale. The globally correlatable nature of these observed carbon isotope shifts, as well as an absence of lithologic evidence for oxygen limitation, points to thermal stress brought on by pulses of volcanism as the shared cause between recovery collapse and carbon cycle perturbations. We propose that the "early" recovery at Blacktail Creek was truncated by recurrent greenhouse gas induced thermal spikes, highlighting the interplay of local and global environmental conditions in expediting or hindering Early Triassic recovery.

  6. Optimal right heart filling pressure in acute respiratory distress syndrome determined by strain echocardiography.

    PubMed

    Garcia-Montilla, Romel; Imam, Faryal; Miao, Mi; Stinson, Kathryn; Khan, Akram; Heitner, Stephen

    2017-06-01

    Right ventricular (RV) systolic dysfunction is common in acute respiratory distress syndrome (ARDS). While preload optimization is crucial in its management, dynamic fluid responsiveness indices lack reliability, and there is no consensus on target central venous pressure (CVP). We analyzed the utility of RV free wall longitudinal strain (RVFWS) in the estimation of optimal RV filling pressure in ARDS. A retrospective cross-sectional analysis of clinical data and echocardiograms of patients with ARDS was performed. Tricuspid annular plane systolic excursion (TAPSE), tricuspid peak systolic velocity (S'), RV fractional area change (RVFAC), RVFWS, CVP, systolic pulmonary artery pressure (SPAP), and left ventricular ejection fraction (LVEF) were measured. Fifty-one patients with moderate-severe ARDS were included. There were inverse correlations between CVP and TAPSE, S', RVFAC, RVFWS, and LVEF. The most significant was with RVFWS (r:.74, R 2 :.55, P:.00001). Direct correlations with creatinine and lactate were noted. Receiver operating characteristic analysis showed that RVFWS -21% (normal reference value) was associated with CVP: 13 mm Hg (AUC: 0.92, 95% CI: 0.83-1.00). Regression model analysis of CVP, and RVFWS interactions established an RVFWS range from -18% to -24%. RVFWS -24% corresponded to CVP: 11 mm Hg and RVFWS -18% to CVP: 15 mm Hg. Beyond a CVP of 15 mm Hg, biventricular systolic dysfunction rapidly ensues. Our data are the first to show that an RV filling pressure of 13±2 mm Hg-as by CVP-correlates with optimal RV mechanics as evaluated by strain echocardiography in patients with moderate-severe ARDS. © 2017, Wiley Periodicals, Inc.

  7. A late Devonian impact event and its association with a possible extinction event on Eastern Gondwana

    NASA Technical Reports Server (NTRS)

    Wang, K.; Geldsetzer, H. H. J.

    1992-01-01

    Evidence from South China and Western Australia for a 365-Ma impact event in the Lower crepida conodont zone of the Famennian stage of the Late Devonian (about 1.5 Ma after the Frasnian/Famennian extinction event) includes microtektitelike glassy microspherules, geochemical anomalies (including a weak Ir), a probable impact crater (greater than 70 k) at Taihu in South China, and an Ir anomaly in Western Australia. A brachiopod faunal turnover in South China, and the 'strangelove ocean'-like c-delta 13 excursions in both Chinese and Australian sections indicate that at least a regional-scale extinction might have occurred at the time of the impact. A paleoreconstruction shows that South China was very close to and facing Western Australia in the Late Devonian. The carbon isotopic excursions, which occur at the same stratigraphic level in both South China and Western Australia cannot be explained as being coincidental. The c-delta 13 excursions and the brachiopod faunal turnover in South China indicate that there might have been at least a regional (possibly global) extinction in the Lower crepida zone. The impact-derived microspherules and geochemical anomalies (especially the Ir) indicate a Lower crepida zone impact event on eastern Gondwana. The location, type of target rocks, and possibly age of the Taihu Lake crater qualify as the probable site of this Late Devonian impact.

  8. Right ventricular systolic function in hypertensive heart failure.

    PubMed

    Oketona, O A; Balogun, M O; Akintomide, A O; Ajayi, O E; Adebayo, R A; Mene-Afejuku, T O; Oketona, O T; Bamikole, O J

    2017-01-01

    Heart failure (HF) is a major cause of cardiovascular admissions and hypertensive heart failure (HHF) is the most common cause of HF admissions in sub-Saharan Africa, Nigeria inclusive. Right ventricular (RV) dysfunction is being increasingly recognized in HF and found to be an independent predictor of adverse outcomes in HF. This study aimed to determine the prevalence of RV systolic dysfunction in HHF by several echocardiographic parameters. One hundred subjects with HHF were recruited consecutively into the study along with 50 age and sex-matched controls. All study participants gave written informed consent, and had a full physical examination, blood investigations, 12-lead electrocardiogram, and transthoracic echocardiography. RV systolic function was assessed in all subjects using different methods based on the American Society of Echocardiography guidelines for echocardiographic assessment of the right heart in adults. This included tricuspid annular plane systolic excursion (TAPSE), RV myocardial performance index (MPI), and RV systolic excursion velocity by tissue Doppler (S'). RV systolic dysfunction was found in 53% of subjects with HHF by TAPSE, 56% by RV MPI, and 48% by tissue Doppler systolic excursion S'. RV systolic dysfunction increased with reducing left ventricular ejection fraction (LVEF) in subjects with HHF. A high proportion of subjects with HHF were found to have RV systolic functional abnormalities using TAPSE, RV MPI, and RV S'. Prevalence of RV systolic dysfunction increased with reducing LVEF.

  9. Sport-specific biomechanical responses to an ACL injury prevention programme: A randomised controlled trial.

    PubMed

    Taylor, Jeffrey B; Ford, Kevin R; Schmitz, Randy J; Ross, Scott E; Ackerman, Terry A; Shultz, Sandra J

    2018-04-19

    Anterior cruciate ligament (ACL) injury prevention programmes have not been as successful at reducing injury rates in women's basketball as in soccer. This randomised controlled trial (ClinicalTrials.gov #NCT02530333) compared biomechanical adaptations in basketball and soccer players during jump-landing activities after an ACL injury prevention programme. Eighty-seven athletes were cluster randomised into intervention (6-week programme) and control groups. Three-dimensional biomechanical analyses of drop vertical jump (DVJ), double- (SAG-DL) and single-leg (SAG-SL) sagittal, and double- (FRONT-DL) and single-leg (FRONT-SL) frontal plane jump landing tasks were tested before and after the intervention. Peak angles, excursions, and joint moments were analysed using two-way MANCOVAs of post-test scores while controlling for pre-test scores. During SAG-SL the basketball intervention group exhibited increased peak knee abduction angles (p = .004) and excursions (p = .003) compared to the basketball control group (p = .01) and soccer intervention group (p = .01). During FRONT-SL, the basketball intervention group exhibited greater knee flexion excursion after training than the control group (p = .01), but not the soccer intervention group (p = .11). Although women's soccer players exhibit greater improvements in knee abduction kinematics than basketball players, these athletes largely exhibit similar biomechanical adaptations to ACL injury prevention programmes.

  10. Right ventricular involvement in patients with inferior myocardial infarction, correlation of electrocardiographic findings with echocardiography data.

    PubMed

    Javed, Sumbul; Rajani, Ali Raza; Govindaswamy, Pushparani; Radaideh, Ghazi Ahmed; Abubaraka, Harb Ahmed; Qureshi, Tariq Ilyas; Arshad, Hassaan Bin

    2017-03-01

    To determine the right ventricular involvement in patients with inferior myocardial infarction by echocardiography in relation to electrocardiographic findings. This observational, prospective study was conducted at Rashid Hospital, Dubai, the United Arab Emirates, from January to September 2013, and comprised patients with inferior myocardial infarction. All patients aged above 18 years were included. Right ventricular myocardial infarction was defined by the electrocardiographic criteria of > 1mV ST elevation in V4R-V5R leads. RV infarction was assessed on echocardiography by fractional area change, tricuspid annular plane systolic excursion and tricuspid annular systolic velocity by tissue Doppler imaging. SPSS 21 was used for data analysis. Of the 73 patients, there were 68(93%) men and 5(7%) women. The three modalities used to assess the right ventricular infarction showed right ventricular involvement in 36(49.3%) cases by fractional area change, 28(38.4%) cases by tricuspid annular plane systolic excursion and 31(42.5%) cases by tissue Doppler imaging in patients with inferior myocardial infarction. Tissue Doppler imaging and right ventricular function showed low degree of negative correlation (p=0.16) while the correlation between tricuspid annular plane systolic excursion and right ventricular function showed significant positive correlation (p<0.0001). Assessment of right ventricular infarction by echocardiography helped to diagnose right ventricular infarction in greater number of cases compared to surface electrocardiogram.

  11. The Long-term Light Curves of X-ray Binaries Contain Simultaneous Periodic and Random Components

    NASA Technical Reports Server (NTRS)

    White, Nicholas E. (Technical Monitor); Boyd, Patricia T.; Smale, Alan P.

    2002-01-01

    LMC X-3 and Cyg X-2 show large amplitude X-ray fluctuations that have been attributed to a warped accretion disk. Cyg X-3 displays high amplitude, apparently non-periodic oscillations. We reanalyze these systems using RXTE ASM data and time-frequency decomposition techniques. We find that the long-term variations in Cyg X-2 can be completely characterized by excursions whose durations are integer multiples of the orbital period, including one essentially identical to the reported "period" of 78 days. Cyg X-3 can be characterized in terms of integer multiples of a 71-day fundamental period unrelated to the 4.8 day orbital period, but suggestively close to the approximately equal to greater than 60 day reported precession period of the relativistic jet inferred from recent radio observations. The long-term excursions of LMC X-3 are related to each other by rational fractions, suggesting the characteristic time scale is 10.594 days, shorter than any observed excursion to date. We explore the phase space evolution of the light curves using a natural embedding and find that all three systems possess two rotation centers that organize the phase space trajectories, one of low luminosity and the other of high luminosity. The implications of this repeatable behavior on generic models of accretion disk dynamics and mass transfer variability are explored.

  12. Correlation of continuous glucose monitoring profiles with pregnancy outcomes in nondiabetic women.

    PubMed

    Sung, Joyce F; Kogut, Elizabeth A; Lee, Henry C; Mannan, Jana L; Navabi, Kasra; Taslimi, M Mark; El-Sayed, Yasser Y

    2015-04-01

    To determine whether hyperglycemic excursions detected by continuous glucose monitoring (CGM) correlate with birth weight percentile and other pregnancy outcomes, and whether CGM correlates better with these outcomes than a single glucose value from a 1-hour glucose challenge test (GCT). This was a prospective observational study of 55 pregnant patients without preexisting diabetes, who wore a CGM device for up to 7 days, between 24 and 28 weeks' gestation. The area under the curve (AUC) of hyperglycemic excursions above various thresholds (110, 120, 130, 140, and 180 mg/dL) was calculated. These AUC values, and results from a standard 50-g GCT, were correlated with our primary outcome of birth weight percentile, and secondary outcomes of unplanned operative delivery, pregnancy complications, delivery complications, fetal complications, and neonatal complications. A consistent correlation was seen between all AUC thresholds and birth weight percentile (r = 0.29, p < 0.05 for AUC-110, -120, -130, and -140; r = 0.25, p = 0.07 for AUC-180). This correlation was stronger than that of 1-hour oral GCT (r = -0.02, p = 0.88). There was no association between AUC values and other outcomes. Among nondiabetic pregnant patients, hyperglycemic excursions detected by CGM show a stronger correlation to birth weight percentile than blood glucose values obtained 1-hour after a 50-g oral GCT. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  13. Knee Muscular Control During Jump Landing in Multidirections.

    PubMed

    Sinsurin, Komsak; Vachalathiti, Roongtiwa; Jalayondeja, Wattana; Limroongreungrat, Weerawat

    2016-06-01

    Jump landing is a complex movement in sports. While competing and practicing, athletes frequently perform multi-planar jump landing. Anticipatory muscle activity could influence the amount of knee flexion and prepare the knee for dynamic weight bearing such as landing tasks. The aim of the present study was to examine knee muscle function and knee flexion excursion as athletes naturally performed multi-direction jump landing. Eighteen male athletes performed the jump-landing test in four directions: forward (0°), 30° diagonal, 60° diagonal, and lateral (90°). Muscles tested were vastus medialis (VM), vastus lateralis (VL), rectus femoris (RF), semitendinosus (ST), and biceps femoris (BF). A Vicon(TM) 612 workstation collected the kinematic data. An electromyography was synchronized with the Vicon(TM) Motion system to quantify dynamic muscle function. Repeated measure ANOVA was used to analyze the data. Jump-landing direction significantly influenced (P < 0.05) muscle activities of VL, RF, and ST and knee flexion excursion. Jumpers landed with a trend of decreasing knee flexion excursion and ST muscle activity 100 ms before foot contact progressively from forward to lateral directions of jump landing. A higher risk of knee injury might occur during lateral jump landing than forward and diagonal directions. Athletes should have more practice in jump landing in lateral direction to avoid injury. Landing technique with high knee flexion in multi-directions should be taught to jumpers for knee injury prevention.

  14. Direction-specific impairment of stability limits and falls in children with developmental coordination disorder: Implications for rehabilitation.

    PubMed

    Fong, Shirley S M; Ng, Shamay S M; Chung, Louisa M Y; Ki, W Y; Chow, Lina P Y; Macfarlane, Duncan J

    2016-01-01

    Limit of stability (LOS) is an important yet under-examined postural control ability in children with developmental coordination disorder (DCD). This study aimed to (1) compare the LOS and fall frequencies of children with and without DCD, and (2) explore the relationships between LOS parameters and falls in the DCD population. Thirty primary school-aged children with DCD and twenty age- and sex-matched typically-developing children participated in the study. Postural control ability, specifically LOS in standing, was evaluated using the LOS test. Reaction time, movement velocity, maximum excursion, end point excursion, and directional control were then calculated. Self-reported fall incidents in the previous week were also documented. Multivariate analysis of variance results revealed that children with DCD had shorter LOS maximum excursion in the backward direction compared to the control group (p=0.003). This was associated with a higher number of falls in daily life (rho=-0.556, p=0.001). No significant between-groups differences were found in other LOS-derived outcomes (p>0.05). Children with DCD had direction-specific postural control impairment, specifically, diminished LOS in the backward direction. This is related to their falls in daily life. Therefore, improving LOS should be factored into rehabilitation treatment for children with DCD. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Mandibular movement range in children.

    PubMed

    Machado, Barbara Cristina Zanandréa; Medeiros, Ana Paula Magalhães; Felício, Cláudia Maria de

    2009-01-01

    identification of the mandibular movement range is an important procedure in the evaluation of the stomatognathic system. However, there are few studies in children that focus on normal parameters or abnormalities. to determine the average range of mandibular movements in Brazilian children aged 6 to 12 years; to verify the difference between genders, in each age group, and between the different age groups: 6-8 years; 8.1-10 years; and 10.1-12 years. participants of the study were 240 healthy children selected among regular students from local schools of São Paulo State. The maximum mandibular opening, lateral excursion and protrusive movements, and deviation of the medium line, if present, were measured using a digital caliper. Student T test, Analysis of variance and Tukey test were considered significant for p < 0.05. the mean values observed in the studied sample were: 44.51mm for maximum mandibular opening; 7.71mm for lateral excursion to the right; 7.92mm for lateral excursion to the left; 7.45mm for protrusive movements. No statistical difference was observed between genders. There was a gradual increase in the range of mandibular movements, with significant differences mainly between the ages of 6-8 years and 10.1-12 years. during childhood the range of mandibular movements increases. Age should be considered in this analysis for a greater precision in the diagnosis.

  16. Rayleigh Scattering.

    ERIC Educational Resources Information Center

    Young, Andrew T.

    1982-01-01

    The correct usage of such terminology as "Rayleigh scattering,""Rayleigh lines,""Raman lines," and "Tyndall scattering" is resolved during an historical excursion through the physics of light-scattering by gas molecules. (Author/JN)

  17. Second-Generation Six-Limbed Experimental Robot

    NASA Technical Reports Server (NTRS)

    Kennedy, Brett; Okon, Avi; Aghazarian, Hrand; Robinson, Matthew; Garrett, Michael; Magnone, Lee

    2004-01-01

    The figure shows the LEMUR II - the second generation of the Limbed Excursion Mechanical Utility Robot (LEMUR), which was described in "Six-Legged Experimental Robot" (NPO-20897), NASA Tech Briefs, Vol. 25, No. 12 (December 2001), page 58. The LEMUR II incorporates a number of improvements, including new features, that extend its capabilities beyond those of its predecessor, which is now denoted the LEMUR I. To recapitulate: the LEMUR I was a six-limbed robot for demonstrating robotic capabilities for assembly, maintenance, and inspection. The LEMUR I was designed to be capable of walking autonomously along a truss structure toward a mechanical assembly at a prescribed location and to perform other operations. The LEMUR I was equipped with stereoscopic video cameras and image-data-processing circuitry for navigation and mechanical operations. It was also equipped with a wireless modem, through which it could be commanded remotely. Upon arrival at a mechanical assembly, the LEMUR I would perform simple mechanical operations with one or both of its front limbs. It could also transmit images to a host computer. Each of the six limbs of the LEMUR I was operated independently. Each of the four rear limbs had three degrees of freedom (DOFs), while each of the front two limbs had four DOFs. The front two limbs were designed to hold, operate, and/or be integrated with tools. The LEMUR I included an onboard computer equipped with an assortment of digital control circuits, digital input/output circuits, analog-to-digital converters for input, and digital-to-analog (D/A) converters for output. Feedback from optical encoders in the limb actuators was utilized for closed-loop microcomputer control of the positions and velocities of the actuators. The LEMUR II incorporates the following improvements over the LEMUR I: a) The drive trains for the joints of the LEMUR II are more sophisticated, providing greater torque and accuracy. b) The six limbs are arranged symmetrically about a hexagonal body platform instead of in straight lines along the sides. This symmetrical arrangement is more conducive to omnidirectional movement in a plane. c) The number of degrees of freedom of each of the rear four limbs has been increased by one. Now, every limb has four degrees of freedom: three at the hip (or shoulder, depending on one s perspective) and one at the knee (or elbow, depending on one s perspective). d) Now every limb (instead of only the two front limbs) can perform operations. For this purpose, each limb is tipped with an improved quick-release mechanism for swapping of end-effector tools. e) New end-effector tools have been developed. These include an instrumented rotary driver that accepts all tool bits that have 0.125-in. (3.175-mm)-diameter shanks, a charge-coupled-device video camera, a super bright light-emitting diode for illuminating the work area of the robot, and a generic collet tool that can be quickly and inexpensively modified to accept any cylindrical object up to 0.5 in. (12.7 mm) in diameter. f) The stereoscopic cameras are mounted on a carriage that moves along a circular track, thereby providing for omnidirectional machine vision. g) The control software has been augmented with software that implements innovations reported in two prior NASA Tech Briefs articles: the HIPS algorithm ["Hybrid Image-Plane/Stereo Manipulation" (NPO-30492), Vol. 28, No. 7 (July 2004), page 55] and the CAMPOUT architecture ["An Architecture for Controlling Multiple Robots" (NPO-30345), Vol. 28, No. 10 (October 2004), page 65].

  18. An experimental apparatus to simulate body-powered prosthetic usage: Development and preliminary evaluation.

    PubMed

    Gao, Fan; Rodriguez, Johanan; Kapp, Susan

    2016-06-01

    Harness fitting in the body-powered prosthesis remains more art than science due to a lack of consistent and quantitative evaluation. The aim of this study was to develop a mechanical, human-body-shaped apparatus to simulate body-powered upper limb prosthetic usage and evaluate its capability of quantitative examination of harness configuration. The apparatus was built upon a torso of a wooden mannequin and integrated major mechanical joints to simulate terminal device operation. Sensors were used to register cable tension, cable excursion, and grip force simultaneously. The apparatus allowed the scapula to move up to 127 mm laterally and the load cell can measure the cable tension up to 445 N. Our preliminary evaluation highlighted the needs and importance of investigating harness configurations in a systematic and controllable manner. The apparatus allows objective, systematic, and quantitative evaluation of effects of realistic harness configurations and will provide insightful and working knowledge on harness fitting in upper limb amputees using body-powered prosthesis. © The International Society for Prosthetics and Orthotics 2015.

  19. Thermotaxis is a Robust Mechanism for Thermoregulation in C. elegans Nematodes

    PubMed Central

    Ramot, Daniel; MacInnis, Bronwyn L.; Lee, Hau-Chen; Goodman, Miriam B.

    2013-01-01

    Many biochemical networks are robust to variations in network or stimulus parameters. Although robustness is considered an important design principle of such networks, it is not known whether this principle also applies to higher-level biological processes such as animal behavior. In thermal gradients, C. elegans uses thermotaxis to bias its movement along the direction of the gradient. Here we develop a detailed, quantitative map of C. elegans thermotaxis and use these data to derive a computational model of thermotaxis in the soil, a natural environment of C. elegans. This computational analysis indicates that thermotaxis enables animals to avoid temperatures at which they cannot reproduce, to limit excursions from their adapted temperature, and to remain relatively close to the surface of the soil, where oxygen is abundant. Furthermore, our analysis reveals that this mechanism is robust to large variations in the parameters governing both worm locomotion and temperature fluctuations in the soil. We suggest that, similar to biochemical networks, animals evolve behavioral strategies that are robust, rather than strategies that rely on fine-tuning of specific behavioral parameters. PMID:19020047

  20. 46 CFR 2.10-5 - Exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: (1) Training youth in boating, seamanship, or navigation skills; (2) Educating youth in a course of marine environmental studies; (3) Providing excursions for persons with disabilities as defined under the...

  1. Steady-state phase error for a phase-locked loop subjected to periodic Doppler inputs

    NASA Technical Reports Server (NTRS)

    Chen, C.-C.; Win, M. Z.

    1991-01-01

    The performance of a carrier phase locked loop (PLL) driven by a periodic Doppler input is studied. By expanding the Doppler input into a Fourier series and applying the linearized PLL approximations, it is easy to show that, for periodic frequency disturbances, the resulting steady state phase error is also periodic. Compared to the method of expanding frequency excursion into a power series, the Fourier expansion method can be used to predict the maximum phase error excursion for a periodic Doppler input. For systems with a large Doppler rate fluctuation, such as an optical transponder aboard an Earth orbiting spacecraft, the method can be applied to test whether a lower order tracking loop can provide satisfactory tracking and thereby save the effect of a higher order loop design.

  2. Conducting polymer electrodes for visual prostheses.

    PubMed

    Green, R A; Devillaine, F; Dodds, C; Matteucci, P; Chen, S; Byrnes-Preston, P; Poole-Warren, L A; Lovell, N H; Suaning, G J

    2010-01-01

    Conducting polymers (CPs) have the potential to provide superior neural interfaces to conventional metal electrodes by introducing more efficient charge transfer across the same geometric area. In this study the conducting polymer poly(ethylene dioxythiophene) (PEDOT) was coated on platinum (Pt) microelectrode arrays. The in vitro electrical characteristics were assessed during biphasic stimulation regimes applied between electrode pairs. It was demonstrated that PEDOT could reduce the potential excursion at a Pt electrode interface by an order of magnitude. The charge injection limit of PEDOT was found to be 15 x larger than Pt. Additionally, PEDOT coated electrodes were acutely implanted in the suprachoroidal space of a cat retina. It was demonstrated that PEDOT coated electrodes also had lower potential excursions in vivo and electrically evoked potentials (EEPs) could be detected within the vision cortex.

  3. Specificities of Sightseeing Foot Tour Arrangement for History Related Street with Regard to Karl Marx Street in the Town of Irkutsk

    NASA Astrophysics Data System (ADS)

    Kulakov, A. I.; Shishkanov, V. S.

    2017-11-01

    The paper is devoted to the preparation of an innovative foot itinerary for tourists in Karl Marx Street in the town of Irkutsk. Methodology on preparation of sightseeing tours has been analysed by the authors. The analysis of the methodology has facilitated selecting the criteria to classify the excursions as well as the criteria for assessing and shortlisting the objects for excursion exposure. Some chosen criteria being used in tour arrangement and certain specificities of tour preparation have been revealed which are characteristic particularly for Karl Marx Street as a history-related one. It is also proved in the paper that the itinerary prepared for tourists is in full correspondence with the key innovation objectives in tourism.

  4. Advanced Plasma Propulsion for Human Missions to Jupiter

    NASA Technical Reports Server (NTRS)

    Donahue, Benjamin B.; Pearson, J. Boise

    1999-01-01

    This paper will briefly identify a promising fusion plasma power source, which when coupled with a promising electric thruster technology would provide for an efficient interplanetary transfer craft suitable to a 4 year round trip mission to the Jovian system. An advanced, nearly radiation free Inertial Electrostatic Confinement scheme for containing fusion plasma was judged as offering potential for delivering the performance and operational benefits needed for such high energy human expedition missions, without requiring heavy superconducting magnets for containment of the fusion plasma. Once the Jovian transfer stage has matched the heliocentric velocity of Jupiter, the energy requirements for excursions to its outer satellites (Callisto, Ganymede and Europa) by smaller excursion craft are not prohibitive. The overall propulsion, power and thruster system is briefly described and a preliminary vehicle mass statement is presented.

  5. Variations in Metallicity and Gas Content in Spiral Galaxies: Accidents of Infall

    NASA Astrophysics Data System (ADS)

    Shields, Gregory A.; Robertson, P.; Dave, R.; Blanc, G. A.; Wright, A.

    2013-01-01

    Oxygen abundances are elevated in hydrogen deficient spirals in the Virgo and Pegasus clusters (Robertson et al. 2012, ApJ 748:48, and references therein). We confirm the relationship between O/H and H I deficiency "DEF" for an additional set of cluster spirals. In addition, we find that field spirals show a similar increase in O/H with DEF. Thus, the relationship is not uniquely the result of environmental processes in clusters. Cosmological simulations of galaxy formation predict a qualitatively similar trend of O/H with DEF for field spirals. This reflects excursions of gas content and metallicity above and below the mean mass-metallicity relationship as galaxies evolve. These excursions result from the stochastic effects of mergers and merger-free periods during the evolution.

  6. Intermittent many-body dynamics at equilibrium

    NASA Astrophysics Data System (ADS)

    Danieli, C.; Campbell, D. K.; Flach, S.

    2017-06-01

    The equilibrium value of an observable defines a manifold in the phase space of an ergodic and equipartitioned many-body system. A typical trajectory pierces that manifold infinitely often as time goes to infinity. We use these piercings to measure both the relaxation time of the lowest frequency eigenmode of the Fermi-Pasta-Ulam chain, as well as the fluctuations of the subsequent dynamics in equilibrium. The dynamics in equilibrium is characterized by a power-law distribution of excursion times far off equilibrium, with diverging variance. Long excursions arise from sticky dynamics close to q -breathers localized in normal mode space. Measuring the exponent allows one to predict the transition into nonergodic dynamics. We generalize our method to Klein-Gordon lattices where the sticky dynamics is due to discrete breathers localized in real space.

  7. On the suitability of fibre optical parametric amplifiers for use in all-optical agile photonic networks

    NASA Astrophysics Data System (ADS)

    Gryspolakis, Nikolaos

    The objective of this thesis is to investigate the suitability of fibre optical parametric amplifiers (FOPAs) for use in multi-channel, dynamic networks. First, we investigate their quasi-static behaviour in such an environment. We study the behaviour of a FOPA under realistic conditions and we examine the impact on the gain spectrum of channel addition for several different operating conditions and regimes. In particular, we examine the impact of surviving channel(s) position, input power and channel spacing. We see how these parameters affect the gain tilt as well as its dynamic characteristics, namely the generation of under or over-shoots at the transition point, possible dependence of rise and fall times on any of the aforementioned parameters and how the gain excursions depend on those parameters. For these studies we assume continuous wave operation for all signals. We observe that the gain spectrum changes are a function of the position and the spacing of the channels. We also find that the gain excursion can reach several dBs (up to 5 dB) in the case of channel add/drop and are heavily dependent on the position of the surviving channels. The channels located in the middle of the transmission band are more prone to channel add/drop-induced gain changes. Moreover, we investigate for the first time the FOPA dynamic behaviour in a packet switching scenario. This part of the study assumes that all but one channels normally vary in a packet-switched fashion. The remaining channel (probe channel) is expected to undergo gain variations due to the perturbation of the system experienced by the other channels. Furthermore, we consider several different scenarios for which the channels spacing, per channel input power (PCIP), variance of the power fluctuation and position of the probe channel will change. We find that when the FOPA operates near saturation the target gain is not achieved more than 50% of the time while the peak-to-peak gain excursions can exceed 1 dB. Next, we introduce modulated channels to the amplifier in order to compare their effect on the Bit Error Rate (BER) performance. We consider the impact on FOPAs when employing different modulation formats, such as RZ, NRZ and RZ-DPSK. Carefully selected modulation formats can improve BER performance and reduce the effects of cross-phase modulation, four wave mixing (FWM) products generation or dispersion (non-linear and linear inter-channel interference). Especially for the case of FOPAs, because of the ultra-fast interaction times of the FWM phenomenon, cross gain modulation can be a great deterrent for using FOPAs. We use RZ-DPSK in order to suppress the WDM signal crosstalk. Only by using RZ-DPSK, we obtain an improved receiver sensitivity of 5 dB when operating at 40 Gb/s. Finally, we investigate ways to mitigate such effects as the ones described above (gain excursions, gain tilt, etc.). We demonstrate that by using a ring configuration with optical feedback for the first time in FOPAs, we can achieve all-optical gain clamping (AOGC), mitigating gain excursions and attaining gain, independent of channel input power for a large range of PCIP. For example, with the use of AOGC, we reduce the add/drop-induced gain excursions from 4 dB to 0.6 dB. Also, by the combined use of AOGC and RZ-DPSK, we mitigate most of the aforementioned hindrances described above.

  8. Neptune's inner magnetosphere and aurora: Energetic particle constraints

    NASA Technical Reports Server (NTRS)

    Mauk, B. H.; Krimigis, S. M.; Acuna, M. H.

    1994-01-01

    A dramatic and peculiar dropout of greater than 500-keV ions (but not electrons) was observed within Neptune's inner magnetosphere near 2 R(sub N) as the Voyager 2 spacecraft approached the planet. Unlike a number of other energetic particle features this feature could not be accounted for by known material bodies in the context of the most utilized magnetic field models (neither the offset tilted dipole models nor the spehrical harmonic model 'O8'). However, the configuration of Neptune's inner magnetosphere is highly uncertain. By applying a novel technique, utilizing energetic particle measurements, to constrain the magnetic field configuration of the inner regions, we show that appeals to unobserved materials within Neptune's system are unnecessary, and that the ion dropout feature was, in all likelihood, the result of ion interactions with maximum L excursions of the ring 1989N1R. The constraints also favor the se of the M2 magnetic field model (Selesnick, 1992) over the previous models. An electron feature was probably absent because the electron interactions with the ring occurred substantially before the ion interactions (about 2 hours for the electrons versus a few minutes for the ions). Pitch-angle scattering apparently eliminated the electron signature. Minimum scattering rates determined based on this premise yield enough electron precipitation power to explain the brightest component of Neptune's aurora. We propose that this bright component is analogous to the Earth's diffuse aurora.

  9. Lunar Surface Architecture Utilization and Logistics Support Assessment

    NASA Astrophysics Data System (ADS)

    Bienhoff, Dallas; Findiesen, William; Bayer, Martin; Born, Andrew; McCormick, David

    2008-01-01

    Crew and equipment utilization and logistics support needs for the point of departure lunar outpost as presented by the NASA Lunar Architecture Team (LAT) and alternative surface architectures were assessed for the first ten years of operation. The lunar surface architectures were evaluated and manifests created for each mission. Distances between Lunar Surface Access Module (LSAM) landing sites and emplacement locations were estimated. Physical characteristics were assigned to each surface element and operational characteristics were assigned to each surface mobility element. Stochastic analysis was conducted to assess probable times to deploy surface elements, conduct exploration excursions, and perform defined crew activities. Crew time is divided into Outpost-related, exploration and science, overhead, and personal activities. Outpost-related time includes element deployment, EVA maintenance, IVA maintenance, and logistics resupply. Exploration and science activities include mapping, geological surveys, science experiment deployment, sample analysis and categorizing, and physiological and biological tests in the lunar environment. Personal activities include sleeping, eating, hygiene, exercising, and time off. Overhead activities include precursor or close-out tasks that must be accomplished but don't fit into the other three categories such as: suit donning and doffing, airlock cycle time, suit cleaning, suit maintenance, post-landing safing actions, and pre-departure preparations. Equipment usage time, spares, maintenance actions, and Outpost consumables are also estimated to provide input into logistics support planning. Results are normalized relative to the NASA LAT point of departure lunar surface architecture.

  10. Reinforcing the North Atlantic backbone: revision and extension of the composite splice at ODP Site 982

    NASA Astrophysics Data System (ADS)

    Drury, Anna Joy; Westerhold, Thomas; Hodell, David; Röhl, Ursula

    2018-03-01

    Ocean Drilling Program (ODP) Site 982 represents a key location for understanding the evolution of climate in the North Atlantic over the past 12 Ma. However, concerns exist about the validity and robustness of the underlying stratigraphy and astrochronology, which currently limits the adequacy of this site for high-resolution climate studies. To resolve this uncertainty, we verify and extend the early Pliocene to late Miocene shipboard composite splice at Site 982 using high-resolution XRF core scanning data and establish a robust high-resolution benthic foraminiferal stable isotope stratigraphy and astrochronology between 8.0 and 4.5 Ma. Splice revisions and verifications resulted in ˜ 11 m of gaps in the original Site 982 isotope stratigraphy, which were filled with 263 new isotope analyses. This new stratigraphy reveals previously unseen benthic δ18O excursions, particularly prior to 6.65 Ma. The benthic δ18O record displays distinct, asymmetric cycles between 7.7 and 6.65 Ma, confirming that high-latitude climate is a prevalent forcing during this interval. An intensification of the 41 kyr beat in both the benthic δ13C and δ18O is also observed ˜ 6.4 Ma, marking a strengthening in the cryosphere-carbon cycle coupling. A large ˜ 0.7 ‰ double excursion is revealed ˜ 6.4-6.3 Ma, which also marks the onset of an interval of average higher δ18O and large precession and obliquity-dominated δ18O excursions between 6.4 and 5.4 Ma, coincident with the culmination of the late Miocene cooling. The two largest benthic δ18O excursions ˜ 6.4-6.3 Ma and TG20/22 coincide with the coolest alkenone-derived sea surface temperature (SST) estimates from Site 982, suggesting a strong connection between the late Miocene global cooling, and deep-sea cooling and dynamic ice sheet expansion. The splice revisions and revised astrochronology resolve key stratigraphic issues that have hampered correlation between Site 982, the equatorial Atlantic and the Mediterranean. Comparisons of the revised Site 982 stratigraphy to high-resolution astronomically tuned benthic δ18O stratigraphies from ODP Site 926 (equatorial Atlantic) and Ain el Beida (north-western Morocco) show that prior inconsistencies in short-term excursions are now resolved. The identification of key new cycles at Site 982 further highlights the requirement for the current scheme for late Miocene marine isotope stages to be redefined. Our new integrated deep-sea benthic stable isotope stratigraphy and astrochronology from Site 982 will facilitate future high-resolution late Miocene to early Pliocene climate research.

  11. 30 CFR 56.5001 - Exposure limits for airborne contaminants.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... concentration shall be determined by phase contrast microscopy (PCM) using the OSHA Reference Method in OSHA's.../cc excursion limit, samples shall be further analyzed using transmission electron microscopy...

  12. 30 CFR 56.5001 - Exposure limits for airborne contaminants.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... concentration shall be determined by phase contrast microscopy (PCM) using the OSHA Reference Method in OSHA's.../cc excursion limit, samples shall be further analyzed using transmission electron microscopy...

  13. 30 CFR 56.5001 - Exposure limits for airborne contaminants.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... concentration shall be determined by phase contrast microscopy (PCM) using the OSHA Reference Method in OSHA's.../cc excursion limit, samples shall be further analyzed using transmission electron microscopy...

  14. 30 CFR 56.5001 - Exposure limits for airborne contaminants.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... concentration shall be determined by phase contrast microscopy (PCM) using the OSHA Reference Method in OSHA's.../cc excursion limit, samples shall be further analyzed using transmission electron microscopy...

  15. Sill intrusion driven fluid flow and vent formation in volcanic basins: Modeling rates of volatile release and paleoclimate effects

    NASA Astrophysics Data System (ADS)

    Iyer, Karthik; Schmid, Daniel

    2016-04-01

    Evidence of mass extinction events in conjunction with climate change occur throughout the geological record and may be accompanied by pronounced negative carbon isotope excursions. The processes that trigger such globally destructive changes are still under considerable debate. These include mechanisms such as poisoning from trace metals released during large volcanic eruptions (Vogt, 1972), CO2 released from lava degassing during the formation of Large Igneous Provinces (LIPs) (Courtillot and Renne, 2003) and CH4 release during the destabilization of sub-seafloor methane (Dickens et al., 1995), to name a few. Thermogenic methane derived from contact metamorphism associated with magma emplacement and cooling in sedimentary basins has been recently gaining considerable attention as a potential mechanism that may have triggered global climate events in the past (e.g. Svensen and Jamtveit, 2010). The discovery of hydrothermal vent complexes that are spatially associated with such basins also supports the discharge of greenhouse gases into the atmosphere (e.g. Jamtveit et al., 2004; Planke et al., 2005; Svensen et al., 2006). A previous study that investigated this process using a fluid flow model (Iyer et al., 2013) suggested that although hydrothermal plume formation resulting from sill emplacement may indeed release large quantities of methane at the surface, the rate at which this methane is released into the atmosphere is too slow to trigger, by itself, some of the negative δ13C excursions observed in the fossil record over short time scales observed in the fossil record. Here, we reinvestigate the rates of gas release during sill emplacement in a case study from the Harstad Basin off-shore Norway with a special emphasis on vent formation. The presented study is based on a seismic line that crosses multiple sill structures emplaced around 55 Ma within the Lower Cretaceous sediments. A single well-defined vent complex is interpreted above the termination of the main sill in the region. We use a 2D, hybrid FEM/FVM model that solves for fully compressible fluid flow to quantify the thermogenic release and transport of methane and to evaluate flow patterns within these systems. Additionally, vent formation in the model is implemented by simple fracture criteria that modify the permeability structure when the fluid pressure exceeds a threshold determined by the lithostatic pressure. The model with fracture formation is able to reproduce a single vent complex at the observed location above the main sill tip. This is very different from hydrothermal plume formation elsewhere in the region and occurs over short time scales (hundreds of years) and results in fluid focusing in that region. The rate of degassing and the resulting negative δ13C excursion from the vent model is then compared to models where only hydrothermal plume formation results in gas transportation. Lastly, variations in the amount of gas liberated in the system are investigated based on kerogen type and other mineral reactions such as limestone decarbonation and halite breakdown in the affected source rock.

  16. Computational Analysis of Pharyngeal Swallowing Mechanics in Patients with Motor Neuron Disease: A Pilot Investigation.

    PubMed

    Garand, K L; Schwertner, Ryan; Chen, Amy; Pearson, William G

    2018-04-01

    Swallowing impairment (dysphagia) is a common sequela in patients with motor neuron disease (MND). The purpose of this retrospective, observational pilot investigation was to characterize how pharyngeal swallowing mechanics are impacted in patients with MND using a comparison with healthy, non-dysphagic control group. Computational analysis of swallowing mechanics (CASM) was used to determine covariate biomechanics of pharyngeal swallowing from videofluoroscopic assessment in 15 patients with MND and 15 age- and sex-matched healthy controls. Canonical variant analysis with post hoc discriminate function analysis (DFA) was performed on coordinate data mapping functional muscle groups underlying pharyngeal swallowing. Differences in swallowing mechanics associated with group (MND; control), motor neuron predominance (upper; lower), onset (bulbar; spinal), and swallow task (thin, pudding) were evaluated and visualized. Pharyngeal swallowing mechanics differed significantly in patients with MND compared with healthy controls (D = 2.01, p < 0.0001). Post hoc DFA pairwise comparisons suggest differences in pharyngeal swallow mechanics by motor neuron predominance (D = 5.03, p < 0.0001), onset (D = 2.03, p < 0.0001), and swallow task (D = 1.04, p < 0.0001). Pharyngeal swallowing mechanics of patients with MND differ from and are more heterogeneous than healthy controls. These findings suggest patients with MND may compensate reductions in pharyngeal shortening and tongue base retraction by extending the head and neck and increasing hyolaryngeal excursion. This work and further CASM investigations will lead to further insights into development and evaluation of targeted clinical treatments designed to prolong safe and efficient swallowing function in patients with MND.

  17. Young Athletes After Anterior Cruciate Ligament Reconstruction With Single-Leg Landing Asymmetries at the Time of Return to Sport Demonstrate Decreased Knee Function 2 Years Later.

    PubMed

    Ithurburn, Matthew P; Paterno, Mark V; Ford, Kevin R; Hewett, Timothy E; Schmitt, Laura C

    2017-09-01

    Previous work shows that young athletes after anterior cruciate ligament reconstruction (ACLR) demonstrate single-leg (SL) landing movement asymmetries at the time of return to sport (RTS); however, the effect of movement asymmetries on longitudinal knee-related function after ACLR has not been examined. Hypothesis/Purpose: The purpose of this study was to examine the effect of SL drop-landing movement symmetry at the time of RTS on knee-related function 2 years later in young athletes after ACLR. The first hypothesis was that young athletes who demonstrated SL drop-landing asymmetries at RTS would demonstrate decreased knee function 2 years later compared with those who demonstrated symmetric SL drop-landing mechanics. The second hypothesis was that SL drop-landing movement symmetry at RTS would be associated with knee functional recovery 2 years later. Cohort study; Level of evidence, 2. This study included 48 young athletes who had undergone ACLR and were assessed at the time of RTS (77% female; mean [±SD] age at RTS, 17.6 ± 2.6 years) and followed for 2 years after RTS. Three sagittal-plane landing variables of interest were calculated using 3-dimensional motion analysis during an SL drop-landing task at the time of RTS: knee flexion excursion, peak internal knee extension moment, and peak trunk flexion. The limb symmetry index (LSI) was calculated for each landing variable using the following: LSI = (involved/uninvolved) × 100%. The LSI was used to divide the cohort into symmetric (SYM) and asymmetric (ASYM) groups for each landing variable: knee flexion excursion (SYM: LSI ≥ 90% [n = 23]; ASYM: LSI < 85% [n = 18]), peak internal knee extension moment (SYM: LSI ≥ 90% [n = 19]; ASYM: LSI < 85% [n = 22]), and peak trunk flexion (SYM: LSI ≤ 105% [n = 25]; ASYM: LSI > 115% [n = 19]). At 2 years after RTS, knee-related function was evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee (IKDC) subjective knee form, and performance on SL hop tests. Functional recovery was defined based on literature cutoffs for knee-related functional measures. Differences in 2-year function were compared between the symmetry groups using Mann-Whitney U tests because of nonnormality. Logistic regression was used to determine if landing symmetry at the time of RTS would be associated with 2-year knee functional recovery after RTS. The ASYM knee flexion excursion group demonstrated decreased function at 2 years after RTS compared with the SYM group on the KOOS-Pain (ASYM: 93.0 ± 8.2; SYM: 98.4 ± 3.0; P = .008) and the KOOS-Quality of Life (ASYM: 81.6 ± 16.1; SYM: 94.1 ± 9.7; P = .008). Knee flexion excursion was associated with knee functional recovery on the KOOS-Pain and the KOOS-Quality of Life ( P = .033 and P = .012, respectively) at 2 years after RTS, after controlling for the quadriceps strength LSI and graft type. Young athletes after ACLR with asymmetries in knee kinematics at the time of RTS reported decreased self-reported function 2 years later; however, the clinical importance of these differences needs to be further understood.

  18. Modification of a Limbed Robot to Favor Climbing

    NASA Technical Reports Server (NTRS)

    Okon, Avi; Kennedy, Brett; Garrett, Michael; Magnone, Lee

    2006-01-01

    The figure shows the LEMUR IIb, which is a modified version of the LEMUR II the second generation of the Limbed Excursion Mechanical Utility Robot (LEMUR). Except as described below, the LEMUR IIb hardware is mostly the same as that of the LEMUR II. The IIb and II versions differ in their kinematic configurations and characteristics associated with their kinematic configurations. The differences are such that relative to the LEMUR II, the LEMUR IIb is simpler and is better suited to climbing on inclined surfaces. The first-generation LEMUR, now denoted the LEMUR I, was described in Six-Legged Experimental Robot (NPO-20897), NASA Tech Briefs, Vol. 25, No. 12 (December 2001), page 58. The LEMUR II was described in Second-Generation Six-Limbed Experimental Robot (NPO-35140) NASA Tech Briefs, Vol. 28, No. 11 (November 2004), page 55. To recapitulate: the LEMUR I and LEMUR II were six-legged or sixlimbed robots for demonstrating robotic capabilities for assembly, maintenance, and inspection. They were designed to be capable of walking autonomously along a truss structure toward a mechanical assembly at a prescribed location. They were equipped with stereoscopic video cameras and image-data-processing circuitry for navigation and mechanical operations. They were also equipped with wireless modems, through which they could be commanded remotely. Upon arrival at a mechanical assembly, the LEMUR I would perform simple mechanical operations by use of one or both of its front legs (or in the case of the LEMUR II, any of its limbs could be used to perform mechanical operations). Either LEMUR could also transmit images to a host computer. The differences between the LEMUR IIb and the LEMUR II are the following: Whereas the LEMUR II had six limbs, the LEMUR IIb has four limbs. This change has reduced both the complexity and mass of the legs and of the overall robot. Whereas each limb of the LEMUR II had four degrees of freedom (DOFs), each limb of the LEMUR IIb has three DOFs. This change has also reduced both complexity and mass. Notwithstanding the decrease in the number of DOFs, the three remaining DOFs are configured to provide greater dexterity for motion along a surface. To extend reach, the limbs of the LEMUR IIb are 25 percent longer than those of the LEMUR II. Additional benefits stemming from the modifications are that the robot body supported by the limbs is now less massive and its center of gravity is now closer to the surface along which the robot is to move. These benefits have been obtained without sacrificing load-carrying capacity. Hence, overall, the LEMUR IIb is a more adept climber.

  19. Sr isotope variations in the Carnian-Norian succession at Pizzo Mondello, Sicani Mountains, Sicily

    NASA Astrophysics Data System (ADS)

    Onoue, T.; Yamashita, K.; Rigo, M.; Abate, B.

    2017-12-01

    The Norian stage in the Late Triassic is exceptionally long (23 Myr) and was subdivided into three substages: the Lacian, Alaunian, and Sevatian. In order to infer the Norian environmental changes in the western Tethys Ocean, the stratigraphic variations of 87Sr/86Sr in the Upper Triassic limestone succession in Sicily were examined. The Pizzo Mondello section studied here mainly consists of a pelagic carbonate sequence of the Scillato Formation, and ranges in age from Tuvalian (late Carnian) to Rhaetian. The Scillato Formation represents a deep-water pelagic facies deposited along the Sicanian Basin in the western Tethys Ocean. We selected fine-grained limestone samples from both the microfacies of lime-mudstone and wackestone to approximate the primary 87Sr/86Sr signature of the limestone beds. The 87Sr/86Sr values are relatively constant in the Tuvalian and Lacian (early Norian). However, the remarkable rise in 87Sr/86Sr occurred across the Lacian-Alaunian (early-middle Norian) transition. Variations in 87Sr/86Sr values show an increasing trend in 87Sr/86Sr from 0.7077 at the base of Lacian to 0.7080 in the Sevatian (late Norian). In the Sevatian, the 87Sr/86Sr ratios display a sudden negative excursion toward lower values and show a relatively quick recovery to pre-excursion 87Sr/86Sr ratios. Korte et al. (2003) suggested that the rise in the 87Sr/86Sr values from the middle Carnian to the late Norian coincide with the Cimmerian orogeny. Our new 87Sr/86Sr data from the Pizzo Mondello section reveal a comparable trend, with a sharp increase in 87Sr/86Sr within the Alaunian, suggesting the rapid uplift and erosion in the Cimmerian Mountains at this time. The cause of the 87Sr/86Sr excursion in the Sevatian remains uncertain. However, the biostratigraphic record of conodonts suggests that a morphological evolution towards platform-less elements occurred with the beginning of the Sr-isotope excursion.

  20. Authigenic 10Be/9Be Ratio Signatures of the Cosmogenic Nuclide Production Linked to Geomagnetic Dipole Moment Variation During and Since the Brunhes/Matuyama Boundary

    NASA Astrophysics Data System (ADS)

    Simon, Q.; Thouveny, N.; Bourles, D. L.; Ménabréaz, L.; Valet, J. P.; Valery, G.; Choy, S.

    2015-12-01

    The atmospheric production rate of cosmogenic nuclides is linked to the geomagnetic dipole moment (GDM) by a non-linear inverse relationship. Large amplitude GDM variations associated with reversals and excursions can potentially be reconstructed using time variation of the cosmogenic beryllium-10 (10Be) production recorded in ocean sediments. Downcore profiles of authigenic 10Be/9Be ratios (proxy of atmospheric 10Be production) in oceanic cores provide independent and additional records of the evolution of the geomagnetic intensity and complete previous information derived from relative paleointensity (RPI). Here are presented new authigenic 10Be/9Be results obtained from cores MD05-2920 and from the top of core MD05-2930 collected in the West Equatorial Pacific Ocean. Completing data of Ménabréaz et al. (2012, 2014), these results provide the first continuous 10Be production rate sedimentary record covering the last 800 ka. Along these cores, authigenic 10Be/9Be ratio peaks are recorded - within methodological errors - at the stratigraphic level of RPI lows. High-resolution chronologies (δ18O-derived) lead to interpret these peaks as successive global 10Be overproduction events triggered by geomagnetic dipole lows present in the PISO-1500 and Sint-2000 stacks. The largest amplitude 10Be production enhancement is synchronous to the very large decrease of the dipole field associated with the last polarity reversal (772 ka). It is consistent in shape and duration with the peak recorded in core MD90-0961 from the Maldive area (Indian Ocean) (Valet et al. 2014). Two significant 10Be production enhancements are coeval with the Laschamp (41 ka) and Icelandic basin (190 ka) excursions, while 10Be production peaks of lower amplitude correlate to other recognized excursions such as the Blake (120 ka), Pringle-Falls (215 ka), Portuguese Margin (290 ka), Big Lost (540 ka) among others. This study provides new data on the amplitude and timing of dipole field variations, helping to understand the difference between paleosecular variation, excursions, aborted reversals and reversals regimes.

  1. Right ventricular dysfunction affects survival after surgical left ventricular restoration.

    PubMed

    Couperus, Lotte E; Delgado, Victoria; Palmen, Meindert; van Vessem, Marieke E; Braun, Jerry; Fiocco, Marta; Tops, Laurens F; Verwey, Harriëtte F; Klautz, Robert J M; Schalij, Martin J; Beeres, Saskia L M A

    2017-04-01

    Several clinical and left ventricular parameters have been associated with prognosis after surgical left ventricular restoration in patients with ischemic heart failure. The aim of this study was to determine the prognostic value of right ventricular function. A total of 139 patients with ischemic heart failure (62 ± 10 years; 79% were male; left ventricular ejection fraction 27% ± 7%) underwent surgical left ventricular restoration. Biventricular function was assessed with echocardiography before surgery. The independent association between all-cause mortality and right ventricular fractional area change, tricuspid annular plane systolic excursion, and right ventricular longitudinal peak systolic strain was assessed. The additive effect of multiple impaired right ventricular parameters on mortality also was assessed. Baseline right ventricular fractional area change was 42% ± 9%, tricuspid annular plane systolic excursion was 18 ± 3 mm, and right ventricular longitudinal peak systolic strain was -24% ± 7%. Within 30 days after surgery, 15 patients died. Right ventricular fractional area change (hazard ratio, 0.93; 95% confidence interval, 0.88-0.98; P < .01), tricuspid annular plane systolic excursion (hazard ratio, 0.80; 95% confidence interval, 0.66-0.96; P = .02), and right ventricular longitudinal peak systolic strain (hazard ratio, 1.15; 95% confidence interval, 1.05-1.26; P < .01) were independently associated with 30-day mortality, after adjusting for left ventricular ejection fraction and aortic crossclamping time. Right ventricular function was impaired in 21%, 20%, and 27% of patients on the basis of right ventricular fractional area change, tricuspid annular plane systolic excursion, and right ventricular longitudinal peak systolic strain, respectively. Any echocardiographic parameter of right ventricular dysfunction was present in 39% of patients. The coexistence of several impaired right ventricular parameters per patient was independently associated with increased 30-day mortality (hazard ratio, 2.83; 95% confidence interval, 1.64-4.87, P < .01 per additional impaired parameter). Baseline right ventricular systolic dysfunction is independently associated with increased mortality in patients with ischemic heart failure undergoing surgical left ventricular restoration. Copyright © 2016 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  2. The origin of decoupled carbonate and organic carbon isotope signatures in the early Cambrian (ca. 542-520 Ma) Yangtze platform

    NASA Astrophysics Data System (ADS)

    Jiang, Ganqing; Wang, Xinqiang; Shi, Xiaoying; Xiao, Shuhai; Zhang, Shihong; Dong, Jin

    2012-02-01

    The early Cambrian (ca. 542-520 Ma) strata in South China record two prominent negative carbonate carbon isotope (δ13Ccarb) excursions of early Nemakit-Daldynian (N-D) and early Tommotian ages. Across each of these excursions, carbonate and organic carbon isotopes (δ13Ccarb and δ13Corg) are strongly decoupled. Regional correlation across a shelf-to-basin transect shows lateral heterogeneity of δ13Corg during the early-middle N-D but more homogenized δ13Corg values across the basin during the late N-D and Tommotian. The temporal and lateral variations in δ13Corg suggest that decoupled δ13Ccarb and δ13Corg across the N-D δ13Ccarb excursion were possibly caused by diagenetic alteration of organic matter and/or amplification of detrital organic carbon isotope signature in low-TOC carbonates. In contrast, decoupled δ13Ccarb and δ13Corg of the upper N-D and Tommotian were likely resulted from chemoautotrophic-methanotrophic biomass contribution to TOC in organic-rich black shale and carbonates. The decoupled δ13Ccarb-δ13Corg pattern from the lower N-D strata (ca. 542 Ma) shows striking similarities with those from the basal (ca. 635 Ma) and upper (ca. 551 Ma) Doushantuo Formation. In all three cases, decoupled δ13Ccarb-δ13Corg are seen in organic-poor carbonates (TOC ≤ 0.1‰) and coupled δ13Ccarb-δ13Corg occur in organic-rich black shale and carbonates at the end of the negative δ13Ccarb excursion. These similarities suggest that the shift from decoupled to coupled δ13Ccarb-δ13Corg has no causal link with the terminal oxidation of a large oceanic DOC reservoir. Given the pervasive anoxia/euxinia in Ediacaran-early Cambrian oceans, local DOC-rich environments may have been common, but a large oceanic DOC reservoir capable of buffering the δ13C of marine organic matter requires independent evidence.

  3. Marcus Gunn jaw-winking synkinesis: clinical features and management.

    PubMed

    Demirci, Hakan; Frueh, Bartley R; Nelson, Christine C

    2010-07-01

    To evaluate the clinical features including eyelid excursion and management of Marcus Gunn jaw-winking synkinesis (MGJWS). Observational case series. Forty-eight consecutive patients with MGJWS. Clinical features and management of 48 patients with MGJWS were reviewed retrospectively. Upper eyelid excursion was measured and graded. Complications of surgical intervention were evaluated. Resolution of MGJWS and symmetry of upper eyelids in primary position. Excursion of the ptotic eyelid with jaw movement in MGJWS was graded as mild (<2 mm) in 16% of patients, moderate (2-4 mm) in 76% of patients, and severe (> or = 5 mm) in 8% of patients. Thirty patients with moderate or severe MGJWS underwent disabling of the involved levator muscle and bilateral or unilateral frontalis suspension and had more than 6 months of follow-up. After a mean follow-up of 62 months, MGJWS resolved in 29 (97%) patients and improved from 6 mm to 2 mm in 1 (3%) patient. Relative upper eyelid height was within 1 mm in 87% of patients in primary position and within 1 mm in 80% of patients in downgaze. Twenty-six patients had bilateral frontalis suspension with disabling of unilateral levator muscle on the involved side. Relative upper eyelid height was within 1 mm in 88% of patients in the primary position and within 1 mm in 88% of patients in downgaze. Four non-amblyopic patients had unilateral frontalis suspension with levator muscle disabling. Relative upper eyelid height was symmetrical in 75% of the patients in primary position and in 25% of patients in downgaze. Complications included eyelash ptosis in 10% of the patients, loss of eyelid crease in 10%, and entropion in 3%. Most of the patients with MGJWS exhibited moderate eyelid excursion. Disabling of the involved levator muscle and bilateral frontalis suspension and, in selected cases, disabling of the involved levator muscle and unilateral frontalis suspension were effective in the treatment of MGJWS. Eyelash ptosis and loss of eyelid crease were the most common complications, each occurring in 10% of the patients. The author(s) have no proprietary or commercial interest in any materials discussed in this article. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  4. 40Ar/39Ar chronology and paleomagnetism of Quaternary basaltic lavas from the Perşani Mountains (East Carpathians)

    NASA Astrophysics Data System (ADS)

    Panaiotu, C. G.; Jicha, B. R.; Singer, B. S.; Ţugui, A.; Seghedi, I.; Panaiotu, A. G.; Necula, C.

    2013-08-01

    Quaternary volcanism in the Perşani Mountains forms an Na-alkali basaltic province inside the bend area of the Carpathians in the southeastern part of Europe. Previous K-Ar ages and paleomagnetic data reveal several transitional virtual geomagnetic poles, which were tentatively associated with the Cobb Mountain subchron and a Brunhes chron excursion. We report a new paleomagnetic and rock-magnetic study coupled with 40Ar/39Ar geochronology to better constrain the age of geomagnetic reversals or excursions that might be recorded and the timing of volcanism. Of the paleomagnetic directions obtained from sampled lava flows 4 are reversed polarity, 19 are normal polarity and 16 have transitional polarity. 40Ar/39Ar plateau ages determined from incremental heating experiments on groundmass indicate that two of the reversely magnetized lavas erupted at 1142 ± 41 and 800 ± 25 ka, four of the normally magnetized lavas erupted at 1060 ± 10, 1062 ± 24, 684 ± 21, and 683 ± 28 ka, and two transitionally magnetized lavas formed at 1221 ± 11 and 799 ± 21 ka. Both the new 40Ar/39Ar ages and the paleomagnetic data suggest at least five episodes of volcanic activity with the most active periods during the Jaramillo and Brunhes chrons. This results shows that the last phases of alkalic and calc-alkaline magmatism in the South-East Carpathians were contemporaneous. The age of the older transitionally magnetized lava flow is within error of recent unspiked K-Ar and astrochronologic ages for the reversal that defines the onset of the Cobb Mountain normal polarity subchron. The age of the younger transitional lava is similar to that of an excursion that preceded the Matuyama-Brunhes polarity reversal and which has come to be known as the Matuyama-Brunhes precursor. Omitting the excursion data, the dispersion of the virtual geomagnetic poles (around 19°) is larger than the expected value around 45°N from the global compilation, but closer to the value obtained only from the Time Averaged geomagnetic Field Initiative studies.

  5. Carbon cycle perturbations recorded by δ13C of bulk organic matter: the Carnian Pluvial Event in the Dolomites, northern Italy

    NASA Astrophysics Data System (ADS)

    Preto, Nereo; Breda, Anna; Dal Corso, Jacopo; Rigo, Manuel; Roghi, Guido; Spötl, Christoph

    2015-04-01

    A period of increased rainfall occurred in the Carnian (Late Triassic), known as Carnian Pluvial Event (CPE), which is evidenced by major lithological changes in continental and marine successions at tropical latitudes. Increased continental weathering and erosion led to the supply of large amounts of siliciclastics into the marginal basins of the Tethys. Seawater anoxia is also observed locally in semi-restricted basins. Simultaneously, microbial factories on high-relief carbonate platforms were replaced by metazoan factories, forming low-relief carbonate ramps and mixed low-gradient shelves. This environmental change has been shown to be closely associated with a negative carbon isotope excursion. A negative δ13C shift is recorded by bulk organic matter in the Milieres section (central Dolomites) and parallels a coeval excursion in carbon-isotope records of higher plant and marine algal biomarker, thus testifying a global change in the isotopic composition of carbon dioxide in the atmosphere and of dissolved inorganic carbon (DIC) in the ocean. This isotopic excursion was identified in organic carbon records throughout the western Tethys, but so far could not be reproduced convincingly using carbon isotope records from carbonate. A long carbon isotope record was produced from bulk organic matter of the early to late Carnian Milieres - Dibona section in the Dolomites, northern Italy. Carbon isotope analyses of carbonate (limestone and dolomite) were also obtained. This new carbon isotope record illustrates the structure of this complex carbon cycle perturbation related to the CPE. But while sharp carbon isotope oscillations are evident in the bulk organic carbon record, there is no evidence of a similar pattern in carbonate record. It can be shown that the carbon isotope record of carbonates is influenced by fractionation and diagenetic processes that completely obliterated the original δ13C signal. We conclude that the Carnian carbonates of the Dolomites do not record the δ13C of marine DIC. We suggest that the identification of the Carnian carbon isotope excursion in carbonate records may only be possible if the isotopic analyses are coupled with petrographic screening that prove a minimal diagenetic overprint.

  6. Radiocarbon-based carbon source quantification of anomalous isotopic foraminifera in last glacial sediments in the western North Pacific

    NASA Astrophysics Data System (ADS)

    Uchida, Masao; Ohkushi, Ken'ichi; Kimoto, Katsunori; Inagaki, Fumio; Ishimura, Toyoho; Tsunogai, Urumu; Tuzino, Taqumi; Shibata, Yasuyuki

    2008-04-01

    A previous study interpreted extremely 13C-depleted excursions of planktonic and benthic foraminifera in last glacial sediments (17,500 to 25,400 cal years B.P.) of the core retrieved from off Shimokita Peninsula and off Hokkaido, Japan, as evidence for periodic releases of methane, arising from the dissociation of methane hydrate. To better understand the formation process of the 13C-depleted excursions, we conducted high-resolution natural radiocarbon measurements and biogeochemical analyses. We found highly depleted 13C excursions ranging from -10.2‰ to -1.6‰ and -6.8‰ to -1.6‰ in planktonic and benthic foraminifera, respectively. Most of the foraminiferal tests in these horizons were brown, most likely as a result of postdepositional alteration, reflecting the formation of authigenic carbonate on the surface of tests. These alterations were also supported by high levels of Mg-calcite and the acid-leaching test for anomalous foraminifera. To evaluate the carbon sources in the altered foraminifera tests, we quantified the relative contributions of 14C-free methane-derived carbon sources to the formation of authigenic carbonates in foraminifera with depleted 13C excursions using a coupled mass balance isotopic model (14C/C and 13C/12C). The radiocarbon ages of both planktonic and benthic 13C-depleted foraminifera were approximately 600 to 2000 years older than those of normal tests from nearby horizons. The relative contributions of authigenic carbonates derived from the methane oxidizing process reached to ˜22 wt% for planktonic foraminifera and ˜15 wt% for benthic foraminifera. The δ13C values of methane calculated from the mass balance model were between -29‰ and -68‰ for planktonic foraminifera and between -40‰ and -108‰ for benthic foraminifera, consistent with δ13C values reported for thermogenic and abiogenic methane in global methane hydrate reservoirs. These data consistently suggest that methane-related drastic environmental change occurred in the horizons that included δ13C anomalies. This study provides important information for interpreting geological records of the methane hydrate instability associated with climate.

  7. Muscle function during jumping in frogs. I. Sarcomere length change, EMG pattern, and jumping performance.

    PubMed

    Lutz, G J; Rome, L C

    1996-08-01

    We determined the influence of temperature on muscle function during jumping to better understand how the frog muscular system is designed to generate a high level of mechanical power. Maximal jumping performance and the in vivo operating conditions of the semimembranosus muscle (SM), a hip extensor, were measured and related to the mechanical properties of the isolated SM in the accompanying paper [Muscle function during jumping in frogs. II. Mechanical properties of muscle: implication for system design. Am. J. Physiol. 271 (Cell Physiol. 40): C571-C578, 1996]. Reducing temperature from 25 to 15 degrees C caused a 1.75-fold decline in peak mechanical power generation and a proportional decline in aerial jump distance. The hip and knee joint excursions were nearly the same at both temperatures. Accordingly, sarcomeres shortened over the same range (2.4 to 1.9 microns) at both temperatures, corresponding to myofilament overlap at least 90% of maximal. At the low temperature, however, movements were made more slowly. Angular velocities were 1.2- to 1.4-fold lower, and ground contact time was increased by 1.33-fold at 15 degrees C. Average shortening velocity of the SM was only 1.2-fold lower at 15 degrees C than at 25 degrees C. The low Q10 of velocity is in agreement with that predicted for muscles shortening against an inertial load.

  8. 49 CFR 236.1003 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... auxiliary or industry tracks, a segment or route of railroad tracks: (1) Of a Class I railroad, as.... Tourist, scenic, historic, or excursion operations as defined in part 238 of this chapter are not...

  9. Subject-Specific Modeling of Muscle Force and Knee Contact in Total Knee Arthroplasty

    PubMed Central

    Navacchia, Alessandro; Rullkoetter, Paul J.; Schütz, Pascal; List, Renate B.; Fitzpatrick, Clare K.; Shelburne, Kevin B.

    2017-01-01

    Understanding the mechanical loading environment and resulting joint mechanics for activities of daily living in total knee arthroplasty is essential to continuous improvement in implant design. Although survivorship of these devices is good, a substantial number of patients report dissatisfaction with the outcome of their procedure. Knowledge of in vivo kinematics and joint loading will enable improvement in preclinical assessment and refinement of implant geometry. The purpose of this investigation was to describe the mechanics of total knee arthroplasty during a variety of activities of daily living (gait, walking down stairs, and chair rise/sit). Estimates of muscle forces, tibial contact load, location, and pressure distribution was performed through a combination of mobile fluoroscopy data collection, musculoskeletal modeling, and finite element simulation. For the activities evaluated, joint compressive load was greatest during walking down stairs; however, the highest contact pressure occurred during chair rise/sit. The joint contact moment in the frontal plane was mainly varus for gait and walking down stairs, while it was valgus during chair rise/sit. Excursion of the center of pressure on the tibial component was similar during each activity and between the medial and lateral sides. The main determinants of center of pressure location were internal–external rotation, joint load, and tibial insert conformity. PMID:26792665

  10. Operation Lightship

    ERIC Educational Resources Information Center

    Reed, Judith

    1973-01-01

    Describes activities abroad Liberty Chesapeake,'' a 133-foot-long retired lightship moored off the East Potomac Park, Washington, D.C., and used as a public excursion boat and floating laboratory by the U.S. National Park Service. (DS)

  11. 40 CFR 146.32 - Construction requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... designed for the life expectancy of the well. In determining and specifying casing and cementing... affected by the mining operation. These wells shall be located in such a fashion as to detect any excursion...

  12. 75 FR 38878 - Transportation for Individuals With Disabilities: Passenger Vessels

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ..., excursion vessels, sightseeing vessels, floating restaurants, cruise ships, and others. Cruise ships are a... the PVO owns or leases the terminal or exercises control over its selection, design, construction, or...

  13. Analysis of the SL-1 Accident Using RELAPS5-3D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Francisco, A.D. and Tomlinson, E. T.

    2007-11-08

    On January 3, 1961, at the National Reactor Testing Station, in Idaho Falls, Idaho, the Stationary Low Power Reactor No. 1 (SL-1) experienced a major nuclear excursion, killing three people, and destroying the reactor core. The SL-1 reactor, a 3 MW{sub t} boiling water reactor, was shut down and undergoing routine maintenance work at the time. This paper presents an analysis of the SL-1 reactor excursion using the RELAP5-3D thermal-hydraulic and nuclear analysis code, with the intent of simulating the accident from the point of reactivity insertion to destruction and vaporization of the fuel. Results are presented, along with amore » discussion of sensitivity to some reactor and transient parameters (many of the details are only known with a high level of uncertainty).« less

  14. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    NASA Astrophysics Data System (ADS)

    Passarella, Marinella; Goldstein, Evan B.; De Muro, Sandro; Coco, Giovanni

    2018-02-01

    We use genetic programming (GP), a type of machine learning (ML) approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared to well-established parameterizations and therefore it may improve coastal hazards assessment (e.g. coastal inundation). Predictors obtained using GP can also be physically sound and replicate the functionality and dependencies of previous published formulas. Overall, we show that ML techniques are capable of both improving predictability (compared to classical regression approaches) and providing physical insight into coastal processes.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Claud, C.; Ovarlez, J.; Chedin, A.

    The authors report on further analysis of a stratospheric cooling event observed by CHEOPS 3 during February 4-6, 1990 over Scandinavia. The CHEOPS 3 observational program provided a large set of data regarding atmospheric conditions in the Arctic polar region which are of use in addressing the question of ozone depletion in the northern hemisphere. A large temperature excursion was observed in this period by the CHEOPS data, and the authors have applied a new inversion to TOVS observations of this same period to attempt to confirm this observation. Such a large excursion would allow the formation of polar stratosphericmore » clouds. They were able to model the general cooling pattern seen by the CHEOPS 3 observations, but not the large temperature dip, and offer an alternative explanation of the accompanying dip in ozone column densities observed over Europe at this time.« less

  16. High-resolution tephrochronology of the Wilson Creek Formation (Mono Lake, California) and Laschamp event using 238U-230Th SIMS dating of accessory mineral rims

    NASA Astrophysics Data System (ADS)

    Vazquez, Jorge A.; Lidzbarski, Marsha I.

    2012-12-01

    Sediments of the Wilson Creek Formation surrounding Mono Lake preserve a high-resolution archive of glacial and pluvial responses along the eastern Sierra Nevada due to late Pleistocene climate change. An absolute chronology for the Wilson Creek stratigraphy is critical for correlating the paleoclimate record to other archives in the western U.S. and the North Atlantic region. However, multiple attempts to date the Wilson Creek stratigraphy using carbonates and tephras yield discordant results due to open-system effects and radiocarbon reservoir uncertainties as well as abundant xenocrysts. New ion microprobe 238U-230Th dating of the final increments of crystallization recorded by allanite and zircon autocrysts from juvenile pyroclasts yield ages that effectively date eruption of key tephra beds and delimit the timing of basal Wilson Creek sedimentation to the interval between 26.8±2.1 and 61.7±1.9 ka. Tephra (Ash 15) erupted during the geomagnetic excursion originally designated the Mono Lake excursion yields an age of 40.8±1.9 ka, indicating that the event is instead the Laschamp excursion. The new ages support a depositional chronology from magnetostratigraphy that indicates quasi-synchronous glacial and hydrologic responses in the Sierra Nevada and Mono Basin to regional climate change, with intervals of lake filling and glacial-snowpack melting that are in phase with peaks in spring insolation.

  17. Influx of Dissolved Silica in Shallow Marine Environments in the Early Rhaetian (Late Triassic): Implications for Timing of Supercontinental Rifting

    NASA Astrophysics Data System (ADS)

    Tackett, L.

    2017-12-01

    The Rhaetian Stage of the Late Triassic terminated with a mass extinction, but the late Norian-early Rhaetian paleoecological and geochemical transitions and their relationship to events leading up to the End-Triassic mass extinction are poorly understood. To address this issue, presented here is a multi-proxy dataset from New York Canyon, Nevada (USA) relating isotope chemostratigraphy (Sr, C, O), shallow marine benthic macrofossils, and microfossils. At this Panthalassan locality the Norian-Rhaetian boundary is characterized by a negative strontium isotope excursion that facilitates correlation with Tethyan deposits. In sedimentary horizons immediately below and above this excursion, siliceous demosponge spicules (desmids) are abundant components of the microfossil populations, and silicification of calcareous microfossils becomes common. In the sedimentary beds marking the main excursion, hexactinellid sponge spicules are abundant. These results indicate a large input of dissolved silica in shallow marine environments, while the negative strontium values are consistent with increased seafloor spreading and hydrothermal vent activity or basalt weathering, either scenario being a plausible silica source for the typically silica-limited sponges that proliferated during this interval. The biosedimentary features observed across the Norian-Rhaetian boundary are similar to those observed in the earliest Jurassic in marine sections around the world following the End-Triassic mass extinction, but no clear biotic turnover is observed across the Norian-Rhaetian boundary in this succession. Thus, biosedimentary shifts across the Norian-Rhaetian boundary may add important geochemical context to the end-Triassic mass extinction event.

  18. A 20-15 ka high-resolution paleomagnetic secular variation record from Black Sea sediments - no evidence for the 'Hilina Pali excursion'?

    NASA Astrophysics Data System (ADS)

    Liu, Jiabo; Nowaczyk, Norbert R.; Frank, Ute; Arz, Helge W.

    2018-06-01

    A comprehensive magnetostratigraphic investigation on sixteen sediment cores from the southeastern Black Sea yielded a very detailed high-quality paleosecular variation (PSV) record spanning from 20 to 15 ka. The age models are based on radiocarbon dating, stratigraphic correlation, and tephrochronology. Further age constraints were obtained by correlating four meltwater events, described from the western Black Sea, ranging in age from about 17 to 15 ka, with maxima in K/Ti ratios, obtained from X-ray fluorescence (XRF) scanning, and minima in S-ratios, reflecting increased hematite content, in the studied cores. Since the sedimentation rates in the investigated time window are up to 50 cm ka-1, the obtained PSVs records enabled a stacking using 50-yr bins. A directional anomaly at 18.5 ka, associated with pronounced swings in inclination and declination, as well as a low in relative paleointensity (rPI), is probably contemporaneous with the Hilina Pali excursion, originally reported from Hawaiian lava flows. However, virtual geomagnetic poles (VGPs) calculated from Black Sea sediments are not located at latitudes lower than 60°N, which denotes normal, though pronounced secular variations. During the postulated Hilina Pali excursion, the VGPs calculated from Black Sea data migrated clockwise only along the coasts of the Arctic Ocean from NE Canada (20.0 ka), via Alaska (18.6 ka) and NE Siberia (18.0 ka) to Svalbard (17.0 ka), then looping clockwise through the Eastern Arctic Ocean.

  19. Biologically induced initiation of Neoproterozoic snowball-Earth events.

    PubMed

    Tziperman, Eli; Halevy, Itay; Johnston, David T; Knoll, Andrew H; Schrag, Daniel P

    2011-09-13

    The glaciations of the Neoproterozoic Era (1,000 to 542 MyBP) were preceded by dramatically light C isotopic excursions preserved in preglacial deposits. Standard explanations of these excursions involve remineralization of isotopically light organic matter and imply strong enhancement of atmospheric CO(2) greenhouse gas concentration, apparently inconsistent with the glaciations that followed. We examine a scenario in which the isotopic signal, as well as the global glaciation, result from enhanced export of organic matter from the upper ocean into anoxic subsurface waters and sediments. The organic matter undergoes anoxic remineralization at depth via either sulfate- or iron-reducing bacteria. In both cases, this can lead to changes in carbonate alkalinity and dissolved inorganic pool that efficiently lower the atmospheric CO(2) concentration, possibly plunging Earth into an ice age. This scenario predicts enhanced deposition of calcium carbonate, the formation of siderite, and an increase in ocean pH, all of which are consistent with recent observations. Late Neoproterozoic diversification of marine eukaryotes may have facilitated the episodic enhancement of export of organic matter from the upper ocean, by causing a greater proportion of organic matter to be partitioned as particulate aggregates that can sink more efficiently, via increased cell size, biomineralization or increased CN of eukaryotic phytoplankton. The scenario explains isotopic excursions that are correlated or uncorrelated with snowball initiation, and suggests that increasing atmospheric oxygen concentrations and a progressive oxygenation of the subsurface ocean helped to prevent snowball glaciation on the Phanerozoic Earth.

  20. High-resolution tephrochronology of the Wilson Creek Formation (Mono Lake, California) and Laschamp event using 238U-230Th SIMS dating of accessory mineral rims

    USGS Publications Warehouse

    Vazquez, Jorge A.; Lidzbarski, Marsha I.

    2012-01-01

    Sediments of the Wilson Creek Formation surrounding Mono Lake preserve a high-resolution archive of glacial and pluvial responses along the eastern Sierra Nevada due to late Pleistocene climate change. An absolute chronology for the Wilson Creek stratigraphy is critical for correlating the paleoclimate record to other archives in the western U.S. and the North Atlantic region. However, multiple attempts to date the Wilson Creek stratigraphy using carbonates and tephras yield discordant results due to open-system effects and radiocarbon reservoir uncertainties as well as abundant xenocrysts. New ion microprobe 238U-230Th dating of the final increments of crystallization recorded by allanite and zircon autocrysts from juvenile pyroclasts yield ages that effectively date eruption of key tephra beds and delimit the timing of basal Wilson Creek sedimentation to the interval between 26.8±2.1 and 61.7±1.9 ka. Tephra (Ash 15) erupted during the geomagnetic excursion originally designated the Mono Lake excursion yields an age of 40.8±1.9 ka, indicating that the event is instead the Laschamp excursion. The new ages support a depositional chronology from magnetostratigraphy that indicates quasi-synchronous glacial and hydrologic responses in the Sierra Nevada and Mono Basin to regional climate change, with intervals of lake filling and glacial-snowpack melting that are in phase with peaks in spring insolation.

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