Sample records for exhibit significant spatial

  1. Life expectancy impacts due to heating energy utilization in China: Distribution, relations, and policy implications.

    PubMed

    Wang, Shaobin; Luo, Kunli

    2018-01-01

    The relation between life expectancy and energy utilization is of particular concern. Different viewpoints concerned the health impacts of heating policy in China. However, it is still obscure that what kind of heating energy or what pattern of heating methods is the most related with the difference of life expectancies in China. The aim of this paper is to comprehensively investigate the spatial relations between life expectancy at birth (LEB) and different heating energy utilization in China by using spatial autocorrelation models including global spatial autocorrelation, local spatial autocorrelation and hot spot analysis. The results showed that: (1) Most of heating energy exhibit a distinct north-south difference, such as central heating supply, stalks and domestic coal. Whereas spatial distribution of domestic natural gas and electricity exhibited west-east differences. (2) Consumption of central heating, stalks and domestic coal show obvious spatial dependence. Whereas firewood, natural gas and electricity did not show significant spatial autocorrelation. It exhibited an extinct south-north difference of heat supply, stalks and domestic coal which were identified to show significant positive spatial autocorrelation. (3) Central heating, residential boilers and natural gas did not show any significant correlations with LEB. While, the utilization of domestic coal and biomass showed significant negative correlations with LEB, and household electricity shows positive correlations. The utilization of domestic coal in China showed a negative effect on LEB, rather than central heating. To improve the solid fuel stoves and control consumption of domestic coal consumption and other low quality solid fuel is imperative to improve the public health level in China in the future. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Reference memory, anxiety and estrous cyclicity in C57BL/6NIA mice are affected by age and sex.

    PubMed

    Frick, K M; Burlingame, L A; Arters, J A; Berger-Sweeney, J

    2000-01-01

    Age-related changes in learning and memory are common in rodents. However, direct comparisons of the effects of aging on learning and memory in both males and females are lacking. The present study examined whether memory deteriorates with increasing age in C57BL/6NIA mice, and whether age-related changes in learning and memory are similar in both sexes. Male and female mice (five, 17 and 25 months of age) were tested in a battery of behavioral tasks including the Morris water maze (spatial and non-spatial reference memory), simple odor discrimination (olfactory reference memory), plus maze (anxiety/exploration), locomotor activity, and basic reflexes. Five-month-old mice learned the water maze and odor discrimination tasks rapidly. Relative to five-month-old mice, 25-month-old mice exhibited impaired spatial and olfactory reference memory, but intact non-spatial reference memory. The spatial reference memory of 17-month-old mice was also impaired, but less so than 25-month mice. Seventeen-month-old mice exhibited intact non-spatial (visual and olfactory) reference memory. Five and 25-month-old mice had similar levels of plus maze exploration and locomotor activity, whereas 17-month-old mice were more active than both groups and were slightly less exploratory than five-month-old mice. Although sex differences were not observed in the five- and 25-month groups, 17-month-old females exhibited more impaired spatial reference memory and increased anxiety relative to 17-month-old males. Estrous cycling in females deteriorated significantly with increased age; all 25-month-old females had ceased cycling and 80% of 17-month-old females displayed either irregular or absent estrous cycling. This study is the first to directly compare age-related mnemonic decline in male and female mice. The results suggest that: (i) aged mice exhibit significant deficits in spatial and olfactory reference memory relative to young mice, whereas middle-aged mice exhibit only a moderate spatial memory deficit and; (ii) spatial reference memory decline begins at an earlier age in females than in males, a finding that may be related to the cessation of estrous cycling.

  3. Time-varying correlations in global real estate markets: A multivariate GARCH with spatial effects approach

    NASA Astrophysics Data System (ADS)

    Gu, Huaying; Liu, Zhixue; Weng, Yingliang

    2017-04-01

    The present study applies the multivariate generalized autoregressive conditional heteroscedasticity (MGARCH) with spatial effects approach for the analysis of the time-varying conditional correlations and contagion effects among global real estate markets. A distinguishing feature of the proposed model is that it can simultaneously capture the spatial interactions and the dynamic conditional correlations compared with the traditional MGARCH models. Results reveal that the estimated dynamic conditional correlations have exhibited significant increases during the global financial crisis from 2007 to 2009, thereby suggesting contagion effects among global real estate markets. The analysis further indicates that the returns of the regional real estate markets that are in close geographic and economic proximities exhibit strong co-movement. In addition, evidence of significantly positive leverage effects in global real estate markets is also determined. The findings have significant implications on global portfolio diversification opportunities and risk management practices.

  4. Impact factors identification of spatial heterogeneity of herbaceous plant diversity on five southern islands of Miaodao Archipelago in North China

    NASA Astrophysics Data System (ADS)

    Chi, Yuan; Shi, Honghua; Wang, Xiaoli; Qin, Xuebo; Zheng, Wei; Peng, Shitao

    2016-09-01

    Herbaceous plants are widely distributed on islands and where they exhibit spatial heterogeneity. Accurately identifying the impact factors that drive spatial heterogeneity can reveal typical island biodiversity patterns. Five southern islands in the Miaodao Archipelago, North China were studied herein. The spatial distribution of herbaceous plant diversity on these islands was analyzed, and the impact factors and their degree of impact on spatial heterogeneity were identified using CCA ordination and ANOVA. The results reveal 114 herbaceous plant species, belonging to 94 genera from 34 families in the 50 plots sampled. The total species numbers on different islands were significantly positively correlated with island area, and the average α diversity was correlated with human activities, while the β diversity among islands was more affected by island area than mutual distances. Spatial heterogeneity within islands indicated that the diversities were generally high in areas with higher altitude, slope, total nitrogen, total carbon, and canopy density, and lower moisture content, pH, total phosphorus, total potassium, and aspect. Among the environmental factors, pH, canopy density, total K, total P, moisture content, altitude, and slope had significant gross effects, but only canopy density exhibited a significant net effect. Terrain affected diversity by restricting plantation, plantation in turn influenced soil properties and the two together affected diversity. Therefore, plantation was ultimately the fundamental driving factor for spatial heterogeneity in herbaceous plant diversity on the five islands.

  5. Toxoplasma gondii strain-dependent effects on mouse behaviour.

    PubMed

    Kannan, Geetha; Moldovan, Krisztina; Xiao, Jian-Chun; Yolken, Robert H; Jones-Brando, Lorraine; Pletnikov, Mikhail V

    2010-06-01

    Toxoplasma gondii reportedly manipulates rodent behaviour to increase transmission to its definitive feline host. We compared the effects of mouse infection by two Type II strains of T. gondii, Prugniaud (PRU) and ME49, on attraction to cat odour, locomotor activity, anxiety, sensorimotor gating, and spatial working and recognition memory 2 months post-infection (mpi). Attraction to cat odour was reassessed 7 mpi. At 2 mpi, mice infected with either strain exhibited significantly more attraction to cat odour than uninfected animals did, but only PRU-infected mice exhibited this behaviour 7 mpi. PRU-infected mice had significantly greater body weights and hyperactivity, while ME49-infected mice exhibited impaired spatial working memory. No differences in parasite antibody titres were seen between PRU- and ME49-infected mice. The present data suggest the effect of T. gondii infection on mouse behaviour is parasite strain-dependent.

  6. Role of high-order aberrations in senescent changes in spatial vision

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elliot, S; Choi, S S; Doble, N

    2009-01-06

    The contributions of optical and neural factors to age-related losses in spatial vision are not fully understood. We used closed-loop adaptive optics to test the visual benefit of correcting monochromatic high-order aberrations (HOAs) on spatial vision for observers ranging in age from 18-81 years. Contrast sensitivity was measured monocularly using a two-alternative forced choice (2AFC) procedure for sinusoidal gratings over 6 mm and 3 mm pupil diameters. Visual acuity was measured using a spatial 4AFC procedure. Over a 6 mm pupil, young observers showed a large benefit of AO at high spatial frequencies, whereas older observers exhibited the greatest benefitmore » at middle spatial frequencies, plus a significantly larger increase in visual acuity. When age-related miosis is controlled, young and old observers exhibited a similar benefit of AO for spatial vision. An increase in HOAs cannot account for the complete senescent decline in spatial vision. These results may indicate a larger role of additional optical factors when the impact of HOAs is removed, but also lend support for the importance of neural factors in age-related changes in spatial vision.« less

  7. [Studies on main interspecific association of rare and endangered medicinal plant Sinopodophyllum hexandrum community in Kangding Zheduo mountain of Sichuan province].

    PubMed

    Liu, Xiang; Zhao, Ji-Feng; Wang, Chang-Hua; Zhang, Zhi-Wei; Qin, Song-Yun; Zhong, Guo-Yue

    2014-07-01

    Based on the 2 x 2 contingency table, by using multi-species relevance (variance ratio, VR), chi2-test, Ochiai index, Dice index, Jaccard index, t-test of v/x and F-test of Morisita, s index, the interspecific relationships and the spatial distribution pattern between 20 dominants in Kangding Zheduo Mountain of Sichuan province were studied. The results indicated that the interspecific association between dominants of Sinopodophyllum hexandrum community in this area did not show significant association, which suggested that the S. hexandrum community was in mature stage, and showed stronger independency, among total 190 pairs in 20 dominant species, 2 species pairs exhibited extremely significantly positive association, 12 species pairs showed significantly positive association, 6 species pairs exhibited significantly negative association and there were no pairs showed extremely significantly negative association. S. hexandrum in community did not show significant association, which indicates they are independent in community, the spatial distribution pattern of S. hexandrum is characterized by random distribution.

  8. Topography and Radiative Forcing Patterns on Glaciers in the Karakoram Himalaya

    NASA Astrophysics Data System (ADS)

    Dobreva, I. D.; Bishop, M. P.; Liu, J. C.; Liang, D.

    2015-12-01

    Glaciers in the western Himalaya exhibit significant spatial variations in morphology and dynamics. Climate, topography and debris cover variations are thought to significantly affect glacier fluctuations and glacier sensitivity to climate change, although the role of topography and radiative forcing have not been adequately characterized and related to glacier fluctuations and dynamics. Consequently, we examined the glaciers in the Karakoram Himalaya, as they exhibit high spatial variability in glacier fluctuation rates and ice dynamics including flow velocity and surging. Specifically, we wanted to examine the relationships between these glacier characteristics and temporal patterns of surface irradiance over the ablation season. To accomplish this, we developed and used a rigorous GIS-based solar radiative transfer model that accounts for the direct and diffuse-skylight irradiance components. The model accounts for multiple topographic effects on the magnitude of irradiance reaching glacier surfaces. We specifically used the ASTER GDEM digital elevation model for irradiance simulations. We then examined temporal patterns of irradiance at the grid-cell level to identify the dominant patterns that were used to train a 3-layer artificial neural network. Our results demonstrate that there are unique spatial and temporal patterns associated with downwasting and surging glaciers, and that these patterns partially account for the spatial distribution of advancing and retreating glaciers. Lower-altitude terminus regions of surging glaciers exhibited relatively low surface irradiance values that decreased in magnitude with time, demonstrating that high-velocity surging glaciers facilitate relief production and exhibit steeper surface irradiance gradients with altitude. Collectively, these results demonstrate the important role that local and regional topography play in governing climate-glacier dynamics in the Himalaya.

  9. The effect of short-range spatial variability on soil sampling uncertainty.

    PubMed

    Van der Perk, Marcel; de Zorzi, Paolo; Barbizzi, Sabrina; Belli, Maria; Fajgelj, Ales; Sansone, Umberto; Jeran, Zvonka; Jaćimović, Radojko

    2008-11-01

    This paper aims to quantify the soil sampling uncertainty arising from the short-range spatial variability of elemental concentrations in the topsoils of agricultural, semi-natural, and contaminated environments. For the agricultural site, the relative standard sampling uncertainty ranges between 1% and 5.5%. For the semi-natural area, the sampling uncertainties are 2-4 times larger than in the agricultural area. The contaminated site exhibited significant short-range spatial variability in elemental composition, which resulted in sampling uncertainties of 20-30%.

  10. The impact of signal-to-noise ratio on contextual cueing in children and adults.

    PubMed

    Yang, Yingying; Merrill, Edward C

    2015-04-01

    Contextual cueing refers to a form of implicit spatial learning where participants incidentally learn to associate a target location with its repeated spatial context. Successful contextual learning produces an efficient visual search through familiar environments. Despite the fact that children exhibit the basic ability of implicit spatial learning, their general effectiveness in this form of learning can be compromised by other development-dependent factors. Learning to extract useful information (signal) in the presence of various amounts of irrelevant or distracting information (noise) characterizes one of the most important changes that occur with cognitive development. This research investigated whether signal-to-noise ratio (S/N) affects contextual cueing differently in children and adults. S/N was operationally defined as the ratio of repeated versus new displays encountered over time. Three ratio conditions were created: high (100%), medium (67%), and low (33%) conditions. Results suggested no difference in the acquisition of contextual learning effects in the high and medium conditions across three age groups (6- to 8-year-olds, 10- to 12-year-olds, and young adults). However, a significant developmental difference emerged in the low S/N condition. As predicted, adults exhibited significant contextual cueing effects, whereas older children showed marginally significant contextual cueing and younger children did not show cueing effects. Group differences in the ability to exhibit implicit contextual learning under low S/N conditions and the implications of this difference are discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Biological and climate factors co-regulated spatial-temporal dynamics of vegetation autumn phenology on the Tibetan Plateau

    NASA Astrophysics Data System (ADS)

    Zu, Jiaxing; Zhang, Yangjian; Huang, Ke; Liu, Yaojie; Chen, Ning; Cong, Nan

    2018-07-01

    Climate change is receiving mounting attentions from various fields and phenology is a commonly used indicator signaling vegetation responses to climate change. Previous phenology studies have mostly focused on vegetation greening-up and its climatic driving factors, while autumn phenology has been barely touched upon. In this study, vegetation phenological metrics were extracted from MODIS NDVI data and their temporal and spatial patterns were explored on the Tibetan Plateau (TP). The results showed that the start of season (SOS) has significantly earlier trend in the first decade, while the end of season (EOS) has slightly (not significant) earlier trend. In the spatial dimension, similar patterns were also identified. The SOS plays a more significant role in regulating vegetation growing season length than EOS does. The EOS and driving effects from each factor exhibited spatially heterogeneous patterns. Biological factor is the dominant factor regulating the spatial pattern of EOS, while climate factors control its inter-annual variation.

  12. Spatial and temporal patterns of locally-acquired dengue transmission in northern Queensland, Australia, 1993-2012.

    PubMed

    Naish, Suchithra; Dale, Pat; Mackenzie, John S; McBride, John; Mengersen, Kerrie; Tong, Shilu

    2014-01-01

    Dengue has been a major public health concern in Australia since it re-emerged in Queensland in 1992-1993. We explored spatio-temporal characteristics of locally-acquired dengue cases in northern tropical Queensland, Australia during the period 1993-2012. Locally-acquired notified cases of dengue were collected for northern tropical Queensland from 1993 to 2012. Descriptive spatial and temporal analyses were conducted using geographic information system tools and geostatistical techniques. 2,398 locally-acquired dengue cases were recorded in northern tropical Queensland during the study period. The areas affected by the dengue cases exhibited spatial and temporal variation over the study period. Notified cases of dengue occurred more frequently in autumn. Mapping of dengue by statistical local areas (census units) reveals the presence of substantial spatio-temporal variation over time and place. Statistically significant differences in dengue incidence rates among males and females (with more cases in females) (χ(2) = 15.17, d.f.  = 1, p<0.01). Differences were observed among age groups, but these were not statistically significant. There was a significant positive spatial autocorrelation of dengue incidence for the four sub-periods, with the Moran's I statistic ranging from 0.011 to 0.463 (p<0.01). Semi-variogram analysis and smoothed maps created from interpolation techniques indicate that the pattern of spatial autocorrelation was not homogeneous across the northern Queensland. Tropical areas are potential high-risk areas for mosquito-borne diseases such as dengue. This study demonstrated that the locally-acquired dengue cases have exhibited a spatial and temporal variation over the past twenty years in northern tropical Queensland, Australia. Therefore, this study provides an impetus for further investigation of clusters and risk factors in these high-risk areas.

  13. Spatial and Temporal Patterns of Locally-Acquired Dengue Transmission in Northern Queensland, Australia, 1993–2012

    PubMed Central

    Naish, Suchithra; Dale, Pat; Mackenzie, John S.; McBride, John; Mengersen, Kerrie; Tong, Shilu

    2014-01-01

    Background Dengue has been a major public health concern in Australia since it re-emerged in Queensland in 1992–1993. We explored spatio-temporal characteristics of locally-acquired dengue cases in northern tropical Queensland, Australia during the period 1993–2012. Methods Locally-acquired notified cases of dengue were collected for northern tropical Queensland from 1993 to 2012. Descriptive spatial and temporal analyses were conducted using geographic information system tools and geostatistical techniques. Results 2,398 locally-acquired dengue cases were recorded in northern tropical Queensland during the study period. The areas affected by the dengue cases exhibited spatial and temporal variation over the study period. Notified cases of dengue occurred more frequently in autumn. Mapping of dengue by statistical local areas (census units) reveals the presence of substantial spatio-temporal variation over time and place. Statistically significant differences in dengue incidence rates among males and females (with more cases in females) (χ2 = 15.17, d.f. = 1, p<0.01). Differences were observed among age groups, but these were not statistically significant. There was a significant positive spatial autocorrelation of dengue incidence for the four sub-periods, with the Moran's I statistic ranging from 0.011 to 0.463 (p<0.01). Semi-variogram analysis and smoothed maps created from interpolation techniques indicate that the pattern of spatial autocorrelation was not homogeneous across the northern Queensland. Conclusions Tropical areas are potential high-risk areas for mosquito-borne diseases such as dengue. This study demonstrated that the locally-acquired dengue cases have exhibited a spatial and temporal variation over the past twenty years in northern tropical Queensland, Australia. Therefore, this study provides an impetus for further investigation of clusters and risk factors in these high-risk areas. PMID:24691549

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaufman, Allan N.; Tracy, Eugene R.; Brizard, Alain J.

    The process of resonant wave conversion (often called linear mode conversion) has traditionally been analyzed with a spatially one-dimensional slab model, for which the rays propagate in a two-dimensional phase space. However, it has recently been shown [E. R. Tracy and A. N. Kaufman, Phys. Rev. Lett. 91, 130402 (2003)] that multidimensional rays have a helical structure for conversion in two or more spatial dimensions (if their dispersion matrix is generic). In that case, a one-dimensional model is inadequate; a correct analysis requires two spatial dimensions and, thus, four-dimensional phase space. A cold-plasma model is introduced in this paper whichmore » exhibits ray helicity in conversion regions where the density and magnetic field gradients are significantly nonparallel. For illustration, such regions are identified in a model of the poloidal plane of a deuterium-tritium tokamak plasma. In each conversion region, characterized by a six-sector topology, rays in the sector for incident and reflected magnetosonic waves exhibit significant helicity. A detailed analytic and numerical study of helical rays in this sector is developed for a 'symmetric-wedge' model.« less

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaufman, Allan N.; Tracy, Eugene R.; Brizard, Alain J.

    The process of resonant wave conversion (often called linear mode conversion) has traditionally been analyzed with a spatially one-dimensional slab model, for which the rays propagate in a two-dimensional phase space. However, it has recently been shown [E.R. Tracy and A.N. Kaufman, Phys. Rev. Lett. 91, 130402 (2003)] that multidimensional rays have a helical structure for conversion in two or more spatial dimensions (if their dispersion matrix is generic). In that case, a one-dimensional model is inadequate; a correct analysis requires two spatial dimensions and, thus, four-dimensional phase space. In this paper we show that a cold plasma model willmore » exhibit ray helicity in conversion regions where the density and magnetic field gradients are significantly non-parallel. For illustration, we examine a model of the poloidal plane of a deuterium-tritium tokamak plasma, and identify such a region. In this region, characterized by a six-sector topology, rays in the sector for incident and reflected magnetosonic waves exhibit significant helicity. We introduce a ''symmetric-wedge'' model, to develop a detailed analytic and numerical study of helical rays in this sector.« less

  16. [GLIATILIN CORRECTION OF WORKING AND REFERENCE SPATIAL MEMORY IMPAIRMENT IN AGED RATS].

    PubMed

    Tyurenkov, I N; Volotova, E V; Kurkin, D V

    2015-01-01

    This work was aimed at evaluating the influence of gliatilin administration on the spatial memory in aged rats. Cognitive function and spatial memory in animals was evaluated using radial (8-beam) maze test. Errors of working spatial memory and reference memory were used as indicators of impaired cognitive function. It was found that aged (24-month) rats compared with younger (6-months) age group exhibited cognitive impairment, as manifested by deterioration of short- and long-term memory processes. Course administration of gliatilin in rats of the older age group at a dose of 100 mg/kg resulted in significant improvement of the working and reference spatial memory in aged rats.

  17. Visual Receptive Field Structure of Cortical Inhibitory Neurons Revealed by Two-Photon Imaging Guided Recording

    PubMed Central

    Liu, Bao-hua; Li, Pingyang; Li, Ya-tang; Sun, Yujiao J.; Yanagawa, Yuchio; Obata, Kunihiko; Zhang, Li I.; Tao, Huizhong W.

    2009-01-01

    Synaptic inhibition plays an important role in shaping receptive field (RF) properties in the visual cortex. However, the underlying mechanisms remain not well understood, partly due to difficulties in systematically studying functional properties of cortical inhibitory neurons in vivo. Here, we established two-photon imaging guided cell-attached recordings from genetically labelled inhibitory neurons and nearby “shadowed” excitatory neurons in the primary visual cortex of adult mice. Our results revealed that in layer 2/3, the majority of excitatory neurons exhibited both On and Off spike subfields, with their spatial arrangement varying from being completely segregated to overlapped. On the other hand, most layer 4 excitatory neurons exhibited only one discernable subfield. Interestingly, no RF structure with significantly segregated On and Off subfields was observed for layer 2/3 inhibitory neurons of either the fast-spike or regular-spike type. They predominantly possessed overlapped On and Off subfields with a significantly larger size than the excitatory neurons, and exhibited much weaker orientation tuning. These results from the mouse visual cortex suggest that different from the push-pull model proposed for simple cells, layer 2/3 simple-type neurons with segregated spike On and Off subfields likely receive spatially overlapped inhibitory On and Off inputs. We propose that the phase-insensitive inhibition can enhance the spatial distinctiveness of On and Off subfields through a gain control mechanism. PMID:19710305

  18. Influence of Pre-Training Predator Stress on the Expression of c-fos mRNA in the Hippocampus, Amygdala, and Striatum Following Long-Term Spatial Memory Retrieval

    PubMed Central

    VanElzakker, Michael B.; Zoladz, Phillip R.; Thompson, Vanessa M.; Park, Collin R.; Halonen, Joshua D.; Spencer, Robert L.; Diamond, David M.

    2011-01-01

    We have studied the influence of pre-training psychological stress on the expression of c-fos mRNA following long-term spatial memory retrieval. Rats were trained to learn the location of a hidden escape platform in the radial-arm water maze, and then their memory for the platform location was assessed 24 h later. Rat brains were extracted 30 min after the 24-h memory test trial for analysis of c-fos mRNA. Four groups were tested: (1) Rats given standard training (Standard); (2) Rats given cat exposure (Predator Stress) 30 min prior to training (Pre-Training Stress); (3) Rats given water exposure only (Water Yoked); and (4) Rats given no water exposure (Home Cage). The Standard trained group exhibited excellent 24 h memory which was accompanied by increased c-fos mRNA in the dorsal hippocampus and basolateral amygdala (BLA). The Water Yoked group exhibited no increase in c-fos mRNA in any brain region. Rats in the Pre-Training Stress group were classified into two subgroups: good and bad memory performers. Neither of the two Pre-Training Stress subgroups exhibited a significant change in c-fos mRNA expression in the dorsal hippocampus or BLA. Instead, stressed rats with good memory exhibited significantly greater c-fos mRNA expression in the dorsolateral striatum (DLS) compared to stressed rats with bad memory. This finding suggests that stressed rats with good memory used their DLS to generate a non-spatial (cue-based) strategy to learn and subsequently retrieve the memory of the platform location. Collectively, these findings provide evidence at a molecular level for the involvement of the hippocampus and BLA in the retrieval of spatial memory and contribute novel observations on the influence of pre-training stress in activating the DLS in response to long-term memory retrieval. PMID:21738501

  19. Hiding in Plain Sight: A Case for Cryptic Metapopulations in Brook Trout (Salvelinus fontinalis)

    PubMed Central

    Kazyak, David C.; Hilderbrand, Robert H.; King, Tim L.; Keller, Stephen R.; Chhatre, Vikram E.

    2016-01-01

    A fundamental issue in the management and conservation of biodiversity is how to define a population. Spatially contiguous fish occupying a stream network have often been considered to represent a single, homogenous population. However, they may also represent multiple discrete populations, a single population with genetic isolation-by-distance, or a metapopulation. We used microsatellite DNA and a large-scale mark-recapture study to assess population structure in a spatially contiguous sample of Brook Trout (Salvelinus fontinalis), a species of conservation concern. We found evidence for limited genetic exchange across small spatial scales and in the absence of barriers to physical movement. Mark-recapture and stationary passive integrated transponder antenna records demonstrated that fish from two tributaries very seldom moved into the opposite tributary, but movements between the tributaries and mainstem were more common. Using Bayesian genetic clustering, we identified two genetic groups that exhibited significantly different growth rates over three years of study, yet survival rates were very similar. Our study highlights the importance of considering the possibility of multiple genetically distinct populations occurring within spatially contiguous habitats, and suggests the existence of a cryptic metapopulation: a spatially continuous distribution of organisms exhibiting metapopulation-like behaviors. PMID:26730588

  20. Spatial probabilistic pulsatility model for enhancing photoplethysmographic imaging systems

    NASA Astrophysics Data System (ADS)

    Amelard, Robert; Clausi, David A.; Wong, Alexander

    2016-11-01

    Photoplethysmographic imaging (PPGI) is a widefield noncontact biophotonic technology able to remotely monitor cardiovascular function over anatomical areas. Although spatial context can provide insight into physiologically relevant sampling locations, existing PPGI systems rely on coarse spatial averaging with no anatomical priors for assessing arterial pulsatility. Here, we developed a continuous probabilistic pulsatility model for importance-weighted blood pulse waveform extraction. Using a data-driven approach, the model was constructed using a 23 participant sample with a large demographic variability (11/12 female/male, age 11 to 60 years, BMI 16.4 to 35.1 kg·m-2). Using time-synchronized ground-truth blood pulse waveforms, spatial correlation priors were computed and projected into a coaligned importance-weighted Cartesian space. A modified Parzen-Rosenblatt kernel density estimation method was used to compute the continuous resolution-agnostic probabilistic pulsatility model. The model identified locations that consistently exhibited pulsatility across the sample. Blood pulse waveform signals extracted with the model exhibited significantly stronger temporal correlation (W=35,p<0.01) and spectral SNR (W=31,p<0.01) compared to uniform spatial averaging. Heart rate estimation was in strong agreement with true heart rate [r2=0.9619, error (μ,σ)=(0.52,1.69) bpm].

  1. Hiding in Plain Sight: A Case for Cryptic Metapopulations in Brook Trout (Salvelinus fontinalis).

    PubMed

    Kazyak, David C; Hilderbrand, Robert H; King, Tim L; Keller, Stephen R; Chhatre, Vikram E

    2016-01-01

    A fundamental issue in the management and conservation of biodiversity is how to define a population. Spatially contiguous fish occupying a stream network have often been considered to represent a single, homogenous population. However, they may also represent multiple discrete populations, a single population with genetic isolation-by-distance, or a metapopulation. We used microsatellite DNA and a large-scale mark-recapture study to assess population structure in a spatially contiguous sample of Brook Trout (Salvelinus fontinalis), a species of conservation concern. We found evidence for limited genetic exchange across small spatial scales and in the absence of barriers to physical movement. Mark-recapture and stationary passive integrated transponder antenna records demonstrated that fish from two tributaries very seldom moved into the opposite tributary, but movements between the tributaries and mainstem were more common. Using Bayesian genetic clustering, we identified two genetic groups that exhibited significantly different growth rates over three years of study, yet survival rates were very similar. Our study highlights the importance of considering the possibility of multiple genetically distinct populations occurring within spatially contiguous habitats, and suggests the existence of a cryptic metapopulation: a spatially continuous distribution of organisms exhibiting metapopulation-like behaviors.

  2. Disease Spread and Its Effect on Population Dynamics in Heterogeneous Environment

    NASA Astrophysics Data System (ADS)

    Upadhyay, Ranjit Kumar; Roy, Parimita

    In this paper, an eco-epidemiological model in which both species diffuse along a spatial gradient has been shown to exhibit temporal chaos at a fixed point in space. The proposed model is a modification of the model recently presented by Upadhyay and Roy [2014]. The spatial interactions among the species have been represented in the form of reaction-diffusion equations. The model incorporates the intrinsic growth rate of fish population which varies linearly with the depth of water. Numerical results show that diffusion can drive otherwise stable system into aperiodic behavior with sensitivity to initial conditions. We show that spatially induced chaos plays an important role in spatial pattern formation in heterogeneous environment. Spatiotemporal distributions of species have been simulated using the diffusivity assumptions realistic for natural eco-epidemic systems. We found that in heterogeneous environment, the temporal dynamics of both the species are drastically different and show chaotic behavior. It was also found that the instability observed in the model is due to spatial heterogeneity and diffusion-driven. Cumulative death rate of predator has an appreciable effect on model dynamics as the spatial distribution of all constituent populations exhibit significant changes when this model parameter is changed and it acts as a regularizing factor.

  3. Ecosystem services trade-offs and determinants in China's Yangtze River Economic Belt from 2000 to 2015.

    PubMed

    Xu, Xibao; Yang, Guishan; Tan, Yan; Liu, Jingping; Hu, Huizhi

    2018-09-01

    Ecosystem services (ES) play an important role in sustaining ecological security, sustainable development and human well-being. This study investigates spatio-temporal changes in five key ES in the Yangtze River Economic Belt of China in 2000-2015-water conservation (WC), soil retention (SR), carbon sequestration (CS), biodiversity conservation (BC) and food supply (FS), by applying three ecological models (InVEST, RUSLE, CASA). Employing scenario simulations, the study quantifies distinct effects of significant factors on ES changes. Using spatial overlapping and Spearman's rank correlation respectively, the study distinguishes spatial patterns of synergies and trade-offs between five ES at the grid and city-scales. The results show that CS, FS, WC and SR presented an overall upward trend, increasing by 22.7%, 16.9%, 6.4% and 4.7%, respectively, while BC remained steady with a marginal degradation. Change in these five ES exhibited dramatic spatial heterogeneity. Across 131 cities, 98.5% of which increased in CS, 87.7% in WC, 68.5% in FS, and 53.1% in SR, while more than half experienced slight degradation in BC. There is high heterogeneity and a great diversity among spatial distributions of ES synergies and trade-offs, which is largely dependent on ES pairs and spatial patterns of land use. Land use/land cover change was the dominant force driving changes in SR, BC and CS, while meteorological factors exhibited a greater effect on WS change than land use/land cover change. The paper examines the synergies between WC-SR, CS-BC and BC-FS on the city level, while WC-BC exhibits significant trade-offs, and no significant relationships for other ES pairs. It is imperative that ES trade-offs at different scales are incorporated to strengthen ecological protection and management policies in project implementation, maintaining ES within vital regions in China. More sophisticated methods and more ES indicators need to be incorporated to enhance the robustness and completeness of assessment. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Agricultural geophysics: Past/present accomplishments and future advancements

    USDA-ARS?s Scientific Manuscript database

    Geophysical methods have become an increasingly valuable tool for application within a variety of agroecosystems. Agricultural geophysics measurements are obtained at a wide range of scales and often exhibit significant variability both temporally and spatially. The three geophysical methods predomi...

  5. The effects of spatial autoregressive dependencies on inference in ordinary least squares: a geometric approach

    NASA Astrophysics Data System (ADS)

    Smith, Tony E.; Lee, Ka Lok

    2012-01-01

    There is a common belief that the presence of residual spatial autocorrelation in ordinary least squares (OLS) regression leads to inflated significance levels in beta coefficients and, in particular, inflated levels relative to the more efficient spatial error model (SEM). However, our simulations show that this is not always the case. Hence, the purpose of this paper is to examine this question from a geometric viewpoint. The key idea is to characterize the OLS test statistic in terms of angle cosines and examine the geometric implications of this characterization. Our first result is to show that if the explanatory variables in the regression exhibit no spatial autocorrelation, then the distribution of test statistics for individual beta coefficients in OLS is independent of any spatial autocorrelation in the error term. Hence, inferences about betas exhibit all the optimality properties of the classic uncorrelated error case. However, a second more important series of results show that if spatial autocorrelation is present in both the dependent and explanatory variables, then the conventional wisdom is correct. In particular, even when an explanatory variable is statistically independent of the dependent variable, such joint spatial dependencies tend to produce "spurious correlation" that results in over-rejection of the null hypothesis. The underlying geometric nature of this problem is clarified by illustrative examples. The paper concludes with a brief discussion of some possible remedies for this problem.

  6. Spatial Variance in Resting fMRI Networks of Schizophrenia Patients: An Independent Vector Analysis

    PubMed Central

    Gopal, Shruti; Miller, Robyn L.; Michael, Andrew; Adali, Tulay; Cetin, Mustafa; Rachakonda, Srinivas; Bustillo, Juan R.; Cahill, Nathan; Baum, Stefi A.; Calhoun, Vince D.

    2016-01-01

    Spatial variability in resting functional MRI (fMRI) brain networks has not been well studied in schizophrenia, a disease known for both neurodevelopmental and widespread anatomic changes. Motivated by abundant evidence of neuroanatomical variability from previous studies of schizophrenia, we draw upon a relatively new approach called independent vector analysis (IVA) to assess this variability in resting fMRI networks. IVA is a blind-source separation algorithm, which segregates fMRI data into temporally coherent but spatially independent networks and has been shown to be especially good at capturing spatial variability among subjects in the extracted networks. We introduce several new ways to quantify differences in variability of IVA-derived networks between schizophrenia patients (SZs = 82) and healthy controls (HCs = 89). Voxelwise amplitude analyses showed significant group differences in the spatial maps of auditory cortex, the basal ganglia, the sensorimotor network, and visual cortex. Tests for differences (HC-SZ) in the spatial variability maps suggest, that at rest, SZs exhibit more activity within externally focused sensory and integrative network and less activity in the default mode network thought to be related to internal reflection. Additionally, tests for difference of variance between groups further emphasize that SZs exhibit greater network variability. These results, consistent with our prediction of increased spatial variability within SZs, enhance our understanding of the disease and suggest that it is not just the amplitude of connectivity that is different in schizophrenia, but also the consistency in spatial connectivity patterns across subjects. PMID:26106217

  7. Gender Dimorphism in Aspartame-Induced Impairment of Spatial Cognition and Insulin Sensitivity

    PubMed Central

    Collison, Kate S.; Makhoul, Nadine J.; Zaidi, Marya Z.; Saleh, Soad M.; Andres, Bernard; Inglis, Angela; Al-Rabiah, Rana; Al-Mohanna, Futwan A.

    2012-01-01

    Previous studies have linked aspartame consumption to impaired retention of learned behavior in rodents. Prenatal exposure to aspartame has also been shown to impair odor-associative learning in guinea pigs; and recently, aspartame-fed hyperlipidemic zebrafish exhibited weight gain, hyperglycemia and acute swimming defects. We therefore investigated the effects of chronic lifetime exposure to aspartame, commencing in utero, on changes in blood glucose parameters, spatial learning and memory in C57BL/6J mice. Morris Water Maze (MWM) testing was used to assess learning and memory, and a random-fed insulin tolerance test was performed to assess glucose homeostasis. Pearson correlation analysis was used to investigate the associations between body characteristics and MWM performance outcome variables. At 17 weeks of age, male aspartame-fed mice exhibited weight gain, elevated fasting glucose levels and decreased insulin sensitivity compared to controls (P<0.05). Females were less affected, but had significantly raised fasting glucose levels. During spatial learning trials in the MWM (acquisition training), the escape latencies of male aspartame-fed mice were consistently higher than controls, indicative of learning impairment. Thigmotactic behavior and time spent floating directionless was increased in aspartame mice, who also spent less time searching in the target quadrant of the maze (P<0.05). Spatial learning of female aspartame-fed mice was not significantly different from controls. Reference memory during a probe test was affected in both genders, with the aspartame-fed mice spending significantly less time searching for the former location of the platform. Interestingly, the extent of visceral fat deposition correlated positively with non-spatial search strategies such as floating and thigmotaxis, and negatively with time spent in the target quadrant and swimming across the location of the escape platform. These data suggest that lifetime exposure to aspartame, commencing in utero, may affect spatial cognition and glucose homeostasis in C57BL/6J mice, particularly in males. PMID:22509243

  8. Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.

    PubMed

    Collison, Kate S; Makhoul, Nadine J; Zaidi, Marya Z; Saleh, Soad M; Andres, Bernard; Inglis, Angela; Al-Rabiah, Rana; Al-Mohanna, Futwan A

    2012-01-01

    Previous studies have linked aspartame consumption to impaired retention of learned behavior in rodents. Prenatal exposure to aspartame has also been shown to impair odor-associative learning in guinea pigs; and recently, aspartame-fed hyperlipidemic zebrafish exhibited weight gain, hyperglycemia and acute swimming defects. We therefore investigated the effects of chronic lifetime exposure to aspartame, commencing in utero, on changes in blood glucose parameters, spatial learning and memory in C57BL/6J mice. Morris Water Maze (MWM) testing was used to assess learning and memory, and a random-fed insulin tolerance test was performed to assess glucose homeostasis. Pearson correlation analysis was used to investigate the associations between body characteristics and MWM performance outcome variables. At 17 weeks of age, male aspartame-fed mice exhibited weight gain, elevated fasting glucose levels and decreased insulin sensitivity compared to controls (P<0.05). Females were less affected, but had significantly raised fasting glucose levels. During spatial learning trials in the MWM (acquisition training), the escape latencies of male aspartame-fed mice were consistently higher than controls, indicative of learning impairment. Thigmotactic behavior and time spent floating directionless was increased in aspartame mice, who also spent less time searching in the target quadrant of the maze (P<0.05). Spatial learning of female aspartame-fed mice was not significantly different from controls. Reference memory during a probe test was affected in both genders, with the aspartame-fed mice spending significantly less time searching for the former location of the platform. Interestingly, the extent of visceral fat deposition correlated positively with non-spatial search strategies such as floating and thigmotaxis, and negatively with time spent in the target quadrant and swimming across the location of the escape platform. These data suggest that lifetime exposure to aspartame, commencing in utero, may affect spatial cognition and glucose homeostasis in C57BL/6J mice, particularly in males.

  9. Role of Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) in local dengue epidemics in Taiwan.

    PubMed

    Tsai, Pui-Jen; Teng, Hwa-Jen

    2016-11-09

    Aedes mosquitoes in Taiwan mainly comprise Aedes albopictus and Ae. aegypti. However, the species contributing to autochthonous dengue spread and the extent at which it occurs remain unclear. Thus, in this study, we spatially analyzed real data to determine spatial features related to local dengue incidence and mosquito density, particularly that of Ae. albopictus and Ae. aegypti. We used bivariate Moran's I statistic and geographically weighted regression (GWR) spatial methods to analyze the globally spatial dependence and locally regressed relationship between (1) imported dengue incidences and Breteau indices (BIs) of Ae. albopictus, (2) imported dengue incidences and BI of Ae. aegypti, (3) autochthonous dengue incidences and BI of Ae. albopictus, (4) autochthonous dengue incidences and BI of Ae. aegypti, (5) all dengue incidences and BI of Ae. albopictus, (6) all dengue incidences and BI of Ae. aegypti, (7) BI of Ae. albopictus and human population density, and (8) BI of Ae. aegypti and human population density in 348 townships in Taiwan. In the GWR models, regression coefficients of spatially regressed relationships between the incidence of autochthonous dengue and vector density of Ae. aegypti were significant and positive in most townships in Taiwan. However, Ae. albopictus had significant but negative regression coefficients in clusters of dengue epidemics. In the global bivariate Moran's index, spatial dependence between the incidence of autochthonous dengue and vector density of Ae. aegypti was significant and exhibited positive correlation in Taiwan (bivariate Moran's index = 0.51). However, Ae. albopictus exhibited positively significant but low correlation (bivariate Moran's index = 0.06). Similar results were observed in the two spatial methods between all dengue incidences and Aedes mosquitoes (Ae. aegypti and Ae. albopictus). The regression coefficients of spatially regressed relationships between imported dengue cases and Aedes mosquitoes (Ae. aegypti and Ae. albopictus) were significant in 348 townships in Taiwan. The results indicated that local Aedes mosquitoes do not contribute to the dengue incidence of imported cases. The density of Ae. aegypti positively correlated with the density of human population. By contrast, the density of Ae. albopictus negatively correlated with the density of human population in the areas of southern Taiwan. The results indicated that Ae. aegypti has more opportunities for human-mosquito contact in dengue endemic areas in southern Taiwan. Ae. aegypti, but not Ae. albopictus, and human population density in southern Taiwan are closely associated with an increased risk of autochthonous dengue incidence.

  10. Divergent drivers of the spatial and temporal variations of cropland carbon transfer in Liaoning province, China.

    PubMed

    Zhu, Xian-Jin; Zhang, Han-Qi; Zhao, Tian-Hong; Li, Jian-Dong; Yin, Hong

    2017-10-12

    Spatial and temporal variations are important points of focus in ecological research. Analysing their differences improves our understanding on the variations of ecological phenomena. Using data from the Liaoning Statistical Yearbook, we investigated the spatial and temporal variations of cropland carbon transfer (CCT), an important ecological phenomenon in quantifying the regional carbon budget, in particular, the influencing factors and difference. The results showed that, from 1992 to 2014, the average CCT in Liaoning province was 18.56 TgC yr -1 and decreased from northwest to southeast. CCT spatial variation was primarily affected by the ratio of planting area to regional area (RPR) via its effect on the magnitude of carbon transfer (MCT), which depended mainly on fertilizer usage per area (FUA). From 1992 to 2014, CCT exhibited a significantly increasing trend with a rate of 0.48 TgC yr -1 . The inter-annual variation of CCT was dominated by carbon transfer per planting area (CTP) through its effect on MCT, which significantly correlated with FUA but showed no significant correlation with climatic factors. Therefore, the factors affecting the spatial variation of CCT differed from those that affected its inter-annual variation, indicating that the spatial and temporal variations of ecological phenomena were affected by divergent factors.

  11. Accuration of Time Series and Spatial Interpolation Method for Prediction of Precipitation Distribution on the Geographical Information System

    NASA Astrophysics Data System (ADS)

    Prasetyo, S. Y. J.; Hartomo, K. D.

    2018-01-01

    The Spatial Plan of the Province of Central Java 2009-2029 identifies that most regencies or cities in Central Java Province are very vulnerable to landslide disaster. The data are also supported by other data from Indonesian Disaster Risk Index (In Indonesia called Indeks Risiko Bencana Indonesia) 2013 that suggest that some areas in Central Java Province exhibit a high risk of natural disasters. This research aims to develop an application architecture and analysis methodology in GIS to predict and to map rainfall distribution. We propose our GIS architectural application of “Multiplatform Architectural Spatiotemporal” and data analysis methods of “Triple Exponential Smoothing” and “Spatial Interpolation” as our significant scientific contribution. This research consists of 2 (two) parts, namely attribute data prediction using TES method and spatial data prediction using Inverse Distance Weight (IDW) method. We conduct our research in 19 subdistricts in the Boyolali Regency, Central Java Province, Indonesia. Our main research data is the biweekly rainfall data in 2000-2016 Climatology, Meteorology, and Geophysics Agency (In Indonesia called Badan Meteorologi, Klimatologi, dan Geofisika) of Central Java Province and Laboratory of Plant Disease Observations Region V Surakarta, Central Java. The application architecture and analytical methodology of “Multiplatform Architectural Spatiotemporal” and spatial data analysis methodology of “Triple Exponential Smoothing” and “Spatial Interpolation” can be developed as a GIS application framework of rainfall distribution for various applied fields. The comparison between the TES and IDW methods show that relative to time series prediction, spatial interpolation exhibit values that are approaching actual. Spatial interpolation is closer to actual data because computed values are the rainfall data of the nearest location or the neighbour of sample values. However, the IDW’s main weakness is that some area might exhibit the rainfall value of 0. The representation of 0 in the spatial interpolation is mainly caused by the absence of rainfall data in the nearest sample point or too far distance that produces smaller weight.

  12. Spatial effects on hybrid electric vehicle adoption

    DOE PAGES

    Liu, Xiaoli; Roberts, Matthew C.; Sioshansi, Ramteen

    2017-03-08

    This paper examines spatial effects on hybrid-electric vehicle (HEV) adoption. This is in contrast to most existing analyses, which concentrate on analyzing socioeconomic factors and demographics. This paper uses a general spatial model to estimate the strength of ‘neighbor effects’ on HEV adoption—namely that each consumer’s HEV-adoption decision can be influenced by the HEV-adoption decisions of geographic neighbors. We use detailed census tract-level demographic data from the 2010 United States Census and the 2012 American Community Survey and vehicle registration data collected by the Ohio Bureau of Motor Vehicles. We find that HEV adoption exhibits significant spatial effects. We furthermore » conduct a time-series analysis and show that historical HEV adoption has a spatial effect on future adoption. Lastly, these results suggest that HEVs may appear in more dense clusters than models that do not consider spatial effects predict.« less

  13. Spatial Autocorrelation of Cancer Incidence in Saudi Arabia

    PubMed Central

    Al-Ahmadi, Khalid; Al-Zahrani, Ali

    2013-01-01

    Little is known about the geographic distribution of common cancers in Saudi Arabia. We explored the spatial incidence patterns of common cancers in Saudi Arabia using spatial autocorrelation analyses, employing the global Moran’s I and Anselin’s local Moran’s I statistics to detect nonrandom incidence patterns. Global ordinary least squares (OLS) regression and local geographically-weighted regression (GWR) were applied to examine the spatial correlation of cancer incidences at the city level. Population-based records of cancers diagnosed between 1998 and 2004 were used. Male lung cancer and female breast cancer exhibited positive statistically significant global Moran’s I index values, indicating a tendency toward clustering. The Anselin’s local Moran’s I analyses revealed small significant clusters of lung cancer, prostate cancer and Hodgkin’s disease among males in the Eastern region and significant clusters of thyroid cancers in females in the Eastern and Riyadh regions. Additionally, both regression methods found significant associations among various cancers. For example, OLS and GWR revealed significant spatial associations among NHL, leukemia and Hodgkin’s disease (r² = 0.49–0.67 using OLS and r² = 0.52–0.68 using GWR) and between breast and prostate cancer (r² = 0.53 OLS and 0.57 GWR) in Saudi Arabian cities. These findings may help to generate etiologic hypotheses of cancer causation and identify spatial anomalies in cancer incidence in Saudi Arabia. Our findings should stimulate further research on the possible causes underlying these clusters and associations. PMID:24351742

  14. Spatial Integration Analysis of Provincial Historical and Cultural Heritage Resources Based on Geographic Information System (gis) — a Case Study of Spatial Integration Analysis of Historical and Cultural Heritage Resources in Zhejiang Province

    NASA Astrophysics Data System (ADS)

    Luo, W.; Zhang, J.; Wu, Q.; Chen, J.; Huo, X.; Zhang, J.; Zhang, Y.; Wang, T.

    2017-08-01

    In China historical and cultural heritage resources include historically and culturally famous cities, towns, villages, blocks, immovable cultural relics and the scenic spots with cultural connotation. The spatial distribution laws of these resources are always directly connected to the regional physical geography, historical development and historical traffic geography and have high research values. Meanwhile, the exhibition and use of these resources are greatly influenced by traffic and tourism and other plans at the provincial level, and it is of great realistic significance to offer proposals on traffic and so on that are beneficial to the exhibition of heritage resources based on the research of province distribution laws. This paper takes the spatial analysis of Geographic Information System (GIS) as the basic technological means and all historical and cultural resources in China's Zhejiang Province as research objects, and finds out in the space the accumulation areas and accumulation belts of Zhejiang Province's historic cities and cultural resources through overlay analysis and density analysis, etc. It then discusses the reasons of the formation of these accumulation areas and accumulation belts by combining with the analysis of physical geography and historical geography and so on, and in the end, linking the tourism planning and traffic planning at the provincial level, it provides suggestions on the exhibition and use of accumulation areas and accumulation belts of historic cities and cultural resources.

  15. Search strategy selection in the Morris water maze indicates allocentric map formation during learning that underpins spatial memory formation.

    PubMed

    Rogers, Jake; Churilov, Leonid; Hannan, Anthony J; Renoir, Thibault

    2017-03-01

    Using a Matlab classification algorithm, we demonstrate that a highly salient distal cue array is required for significantly increased likelihoods of spatial search strategy selection during Morris water maze spatial learning. We hypothesized that increased spatial search strategy selection during spatial learning would be the key measure demonstrating the formation of an allocentric map to the escape location. Spatial memory, as indicated by quadrant preference for the area of the pool formally containing the hidden platform, was assessed as the main measure that this allocentric map had formed during spatial learning. Our C57BL/6J wild-type (WT) mice exhibit quadrant preference in the highly salient cue paradigm but not the low, corresponding with a 120% increase in the odds of a spatial search strategy selection during learning. In contrast, quadrant preference remains absent in serotonin 1A receptor (5-HT 1A R) knockout (KO) mice, who exhibit impaired search strategy selection during spatial learning. Additionally, we also aimed to assess the impact of the quality of the distal cue array on the spatial learning curves of both latency to platform and path length using mixed-effect regression models and found no significant associations or interactions. In contrast, we demonstrated that the spatial learning curve for search strategy selection was absent during training in the low saliency paradigm. Therefore, we propose that allocentric search strategy selection during spatial learning is the learning parameter in mice that robustly indicates the formation of a cognitive map for the escape goal location. These results also suggest that both latency to platform and path length spatial learning curves do not discriminate between allocentric and egocentric spatial learning and do not reliably predict spatial memory formation. We also show that spatial memory, as indicated by the absolute time in the quadrant formerly containing the hidden platform alone (without reference to the other areas of the pool), was not sensitive to cue saliency or impaired in 5-HT 1A R KO mice. Importantly, in the absence of a search strategy analysis, this suggests that to establish that the Morris water maze has worked (i.e. control mice have formed an allocentric map to the escape goal location), a measure of quadrant preference needs to be reported to establish spatial memory formation. This has implications for studies that claim hippocampal functioning is impaired using latency to platform or path length differences within the existing Morris water maze literature. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Spatial Dependence and Determinants of Dairy Farmers' Adoption of Best Management Practices for Water Protection in New Zealand

    NASA Astrophysics Data System (ADS)

    Yang, Wei; Sharp, Basil

    2017-04-01

    This paper analyses spatial dependence and determinants of the New Zealand dairy farmers' adoption of best management practices to protect water quality. A Bayesian spatial durbin probit model is used to survey data collected from farmers in the Waikato region of New Zealand. The results show that farmers located near each other exhibit similar choice behaviour, indicating the importance of farmer interactions in adoption decisions. The results also address that information acquisition is the most important determinant of farmers' adoption of best management practices. Financial problems are considered a significant barrier to adopting best management practices. Overall, the existence of distance decay effect and spatial dependence in farmers' adoption decisions highlights the importance of accounting for spatial effects in farmers' decision-making, which emerges as crucial to the formulation of sustainable agriculture policy.

  17. Spatial Dependence and Determinants of Dairy Farmers' Adoption of Best Management Practices for Water Protection in New Zealand.

    PubMed

    Yang, Wei; Sharp, Basil

    2017-04-01

    This paper analyses spatial dependence and determinants of the New Zealand dairy farmers' adoption of best management practices to protect water quality. A Bayesian spatial durbin probit model is used to survey data collected from farmers in the Waikato region of New Zealand. The results show that farmers located near each other exhibit similar choice behaviour, indicating the importance of farmer interactions in adoption decisions. The results also address that information acquisition is the most important determinant of farmers' adoption of best management practices. Financial problems are considered a significant barrier to adopting best management practices. Overall, the existence of distance decay effect and spatial dependence in farmers' adoption decisions highlights the importance of accounting for spatial effects in farmers' decision-making, which emerges as crucial to the formulation of sustainable agriculture policy.

  18. Spatial/Temporal Variations of Crime: A Routine Activity Theory Perspective.

    PubMed

    de Melo, Silas Nogueira; Pereira, Débora V S; Andresen, Martin A; Matias, Lindon Fonseca

    2018-05-01

    Temporal and spatial patterns of crime in Campinas, Brazil, are analyzed considering the relevance of routine activity theory in a Latin American context. We use geo-referenced criminal event data, 2010-2013, analyzing spatial patterns using census tracts and temporal patterns considering seasons, months, days, and hours. Our analyses include difference in means tests, count-based regression models, and Kulldorff's scan test. We find that crime in Campinas, Brazil, exhibits both temporal and spatial-temporal patterns. However, the presence of these patterns at the different temporal scales varies by crime type. Specifically, not all crime types have statistically significant temporal patterns at all scales of analysis. As such, routine activity theory works well to explain temporal and spatial-temporal patterns of crime in Campinas, Brazil. However, local knowledge of Brazilian culture is necessary for understanding a portion of these crime patterns.

  19. Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories

    PubMed Central

    Donovan, Rory M.; Tapia, Jose-Juan; Sullivan, Devin P.; Faeder, James R.; Murphy, Robert F.; Dittrich, Markus; Zuckerman, Daniel M.

    2016-01-01

    The long-term goal of connecting scales in biological simulation can be facilitated by scale-agnostic methods. We demonstrate that the weighted ensemble (WE) strategy, initially developed for molecular simulations, applies effectively to spatially resolved cell-scale simulations. The WE approach runs an ensemble of parallel trajectories with assigned weights and uses a statistical resampling strategy of replicating and pruning trajectories to focus computational effort on difficult-to-sample regions. The method can also generate unbiased estimates of non-equilibrium and equilibrium observables, sometimes with significantly less aggregate computing time than would be possible using standard parallelization. Here, we use WE to orchestrate particle-based kinetic Monte Carlo simulations, which include spatial geometry (e.g., of organelles, plasma membrane) and biochemical interactions among mobile molecular species. We study a series of models exhibiting spatial, temporal and biochemical complexity and show that although WE has important limitations, it can achieve performance significantly exceeding standard parallel simulation—by orders of magnitude for some observables. PMID:26845334

  20. The pitcher plant flesh fly exhibits a mixture of patchy and metapopulation attributes.

    PubMed

    Rasic, Gordana; Keyghobadi, Nusha

    2012-01-01

    We investigated the pattern of spatial genetic structure and the extent of gene flow in the pitcher plant flesh fly Fletcherimyia fletcheri, the largest member of the inquiline community of the purple pitcher plant Sarracenia purpurea. Using microsatellite loci, we tested the theoretical predictions of different hypothesized population models (patchy population, metapopulation, or isolated populations) among 11 bogs in Algonquin Provincial Park (Canada). Our results revealed that the pitcher plant flesh fly exhibits a mixture of patchy and metapopulation characteristics. There is significant differentiation among bogs and limited gene flow at larger spatial scales, but local populations do not experience frequent local extinctions/recolonizations. Our findings suggest a strong dispersal ability and stable population sizes in F. fletcheri, providing novel insights into the ecology of this member of a unique ecological microcosm.

  1. Establishment of a captive all-male group of proboscis monkey (Nasalis larvatus) at the Singapore Zoo.

    PubMed

    Sha, John Chih Mun; Alagappasamy, Sam; Chandran, Subash; Cho, Khin Maung; Guha, Biswajit

    2013-01-01

    Surplus male proboscis monkeys at the Singapore Zoo pose a considerable problem for maintenance and maximizing of exhibition potential. In 2008, a new exhibit was constructed to house and display a group of six proboscis monkey males born in Singapore Zoo. To document and monitor the all-male group establishment in the new exhibit, we conducted observations on intragroup interactions between the monkeys, spatial use of their new exhibit, and visitor effects on their behavior. We found contact aggressive interactions between the monkeys to be consistently lower than noncontact aggressive interactions and by week six of introduction to the new exhibit, contact aggression was almost nonevident. Affiliative interactions also developed between individuals in the group, with an interface of aggressive and socioreconcilatory behavior influenced by food competition and a dominance hierarchy. This was evident from significantly higher overall aggression and affiliation during feeding times compared to nonfeeding times, and this was reduced when food competition was mitigated by modifying the feeding regime. We measured the groups' spatial use of the exhibit and the relation to behavior, crowd size, and density. Our results showed that the proboscis monkeys utilized the available exhibit space, were largely unaffected by visitor crowd size and density, and were able to exhibit a variety of natural behaviors, including swimming. Our accomplishment in maintaining and displaying an all-male group of proboscis monkeys in captivity provides viable options for more comprehensive captive management and breeding programs for this endangered species. © 2012 Wiley Periodicals, Inc.

  2. Spatially varying geometric phase in classically entangled vector beams of light

    NASA Astrophysics Data System (ADS)

    King-Smith, Andrew; Leary, Cody

    We present theoretical results describing a spatially varying geometric (Pancharatnam) phase present in vector modes of light, in which the polarization and transverse spatial mode degrees of freedom exhibit classical entanglement. We propose an experimental setup capable of characterizing this effect, in which a vector mode propagates through a Mach-Zehnder interferometer with a birefringent phase retarder present in one arm. Since the polarization state of a classically entangled light beam exhibits spatial variation across the transverse mode profile, the phase retarder gives rise to a spatially varying geometric phase in the beam propagating through it. When recombined with the reference beam from the other interferometer arm, the presence of the geometric phase is exhibited in the resulting interference pattern. We acknowledge funding from the Research Corporation for Science Advancement by means of a Cottrell College Science Award.

  3. Significant demographic and fine-scale genetic structure in expanding and senescing populations of the terrestrial orchid Cymbidium goeringii (Orchidaceae).

    PubMed

    Chung, Mi Yoon; Nason, John D; Chung, Myong Gi

    2011-12-01

    Fine-scale genetic structure (FSGS) in plants is influenced by variation in spatial and temporal demographic processes. To determine how demographic structure and FSGS change with stages of population succession, we studied replicate expanding and senescing populations of the Asian terrestrial orchid Cymbidium goeringii. We used spatial autocorrelation methods (O-ring and kinship statistics) to quantify spatial demographic structure and FSGS in two expanding and two senescing populations, also measuring genetic diversity and inbreeding in each. All populations exhibited significant aggregation of individuals and FSGS at short spatial scales. In expanding populations, this finding was associated with high recruitment rates, suggesting restricted seed dispersal. In senescing populations, recruitment was minimal, suggesting alternative mechanisms of aggregation, perhaps including spatial associations with mycorrhizal fungi. All populations had significant evidence of genetic bottlenecks, and inbreeding levels were consistently high. Our results indicate that different successional stages can generate similar patterns of spatial demographic and genetic structure, but as a consequence of different processes. These results contrast with the only other study of senescence effects on population genetic structure in an herbaceous perennial, which found little to no FSGS in senescing populations. With the exception of populations subject to mass collection by orchid sellers, significant FSGS is characteristic of the 16 terrestrial orchid species examined to date. From a conservation perspective, this result suggests that inference of orchid population history will benefit from analyses of both FSGS and demographic structure in combination with other ecological field data.

  4. Individual differences in cardiac vagal tone are associated with differential neural responses to facial expressions at different spatial frequencies: an ERP and sLORETA study.

    PubMed

    Park, Gewnhi; Moon, Eunok; Kim, Do-Won; Lee, Seung-Hwan

    2012-12-01

    A previous study has shown that greater cardiac vagal tone, reflecting effective self-regulatory capacity, was correlated with superior visual discrimination of fearful faces at high spatial frequency Park et al. (Biological Psychology 90:171-178, 2012b). The present study investigated whether individual differences in cardiac vagal tone (indexed by heart rate variability) were associated with different event-related brain potentials (ERPs) in response to fearful and neutral faces. Thirty-six healthy participants discriminated the emotion of fearful and neutral faces at broad, high, and low spatial frequencies, while ERPs were recorded. Participants with low resting heart rate variability-characterized by poor functioning of regulatory systems-exhibited significantly greater N200 activity in response to fearful faces at low spatial frequency and greater LPP responses to neutral faces at high spatial frequency. Source analyses-estimated by standardized low-resolution brain electromagnetic tomography (sLORETA)-tended to show that participants with low resting heart rate variability exhibited increased source activity in visual areas, such as the cuneus and the middle occipital gyrus, as compared with participants with high resting heart rate variability. The hyperactive neural activity associated with low cardiac vagal tone may account for hypervigilant response patterns and emotional dysregulation, which heightens the risk of developing physical and emotional problems.

  5. Dissociation of working memory impairments and attention-deficit/hyperactivity disorder in the brain.

    PubMed

    Mattfeld, Aaron T; Whitfield-Gabrieli, Susan; Biederman, Joseph; Spencer, Thomas; Brown, Ariel; Fried, Ronna; Gabrieli, John D E

    2016-01-01

    Prevailing neuropsychological models of attention-deficit/hyperactivity disorder (ADHD) propose that ADHD arises from deficits in executive functions such as working memory, but accumulating clinical evidence suggests a dissociation between ADHD and executive dysfunctions. This study examined whether ADHD and working memory capacity are behaviorally and neurobiologically separable using functional magnetic resonance imaging (fMRI). Participants diagnosed with ADHD in childhood who subsequently remitted or persisted in their diagnosis as adults were characterized at follow-up in adulthood as either impaired or unimpaired in spatial working memory relative to controls who never had ADHD. ADHD participants with impaired spatial working memory performed worse than controls and ADHD participants with unimpaired working memory during an n-back working memory task while being scanned. Both controls and ADHD participants with unimpaired working memory exhibited significant linearly increasing activation in the inferior frontal junction, precuneus, lingual gyrus, and cerebellum as a function of working-memory load, and these activations did not differ significantly between these groups. ADHD participants with impaired working memory exhibited significant hypoactivation in the same regions, which was significantly different than both control participants and ADHD participants with unimpaired working memory. These findings support both a behavioral and neurobiological dissociation between ADHD and working memory capacity.

  6. Dissociation of working memory impairments and attention-deficit/hyperactivity disorder in the brain

    PubMed Central

    Mattfeld, Aaron T.; Whitfield-Gabrieli, Susan; Biederman, Joseph; Spencer, Thomas; Brown, Ariel; Fried, Ronna; Gabrieli, John D.E.

    2015-01-01

    Prevailing neuropsychological models of attention-deficit/hyperactivity disorder (ADHD) propose that ADHD arises from deficits in executive functions such as working memory, but accumulating clinical evidence suggests a dissociation between ADHD and executive dysfunctions. This study examined whether ADHD and working memory capacity are behaviorally and neurobiologically separable using functional magnetic resonance imaging (fMRI). Participants diagnosed with ADHD in childhood who subsequently remitted or persisted in their diagnosis as adults were characterized at follow-up in adulthood as either impaired or unimpaired in spatial working memory relative to controls who never had ADHD. ADHD participants with impaired spatial working memory performed worse than controls and ADHD participants with unimpaired working memory during an n-back working memory task while being scanned. Both controls and ADHD participants with unimpaired working memory exhibited significant linearly increasing activation in the inferior frontal junction, precuneus, lingual gyrus, and cerebellum as a function of working-memory load, and these activations did not differ significantly between these groups. ADHD participants with impaired working memory exhibited significant hypoactivation in the same regions, which was significantly different than both control participants and ADHD participants with unimpaired working memory. These findings support both a behavioral and neurobiological dissociation between ADHD and working memory capacity. PMID:26900567

  7. Augmented Reality as a Countermeasure for Sleep Deprivation.

    PubMed

    Baumeister, James; Dorrlan, Jillian; Banks, Siobhan; Chatburn, Alex; Smith, Ross T; Carskadon, Mary A; Lushington, Kurt; Thomas, Bruce H

    2016-04-01

    Sleep deprivation is known to have serious deleterious effects on executive functioning and job performance. Augmented reality has an ability to place pertinent information at the fore, guiding visual focus and reducing instructional complexity. This paper presents a study to explore how spatial augmented reality instructions impact procedural task performance on sleep deprived users. The user study was conducted to examine performance on a procedural task at six time points over the course of a night of total sleep deprivation. Tasks were provided either by spatial augmented reality-based projections or on an adjacent monitor. The results indicate that participant errors significantly increased with the monitor condition when sleep deprived. The augmented reality condition exhibited a positive influence with participant errors and completion time having no significant increase when sleep deprived. The results of our study show that spatial augmented reality is an effective sleep deprivation countermeasure under laboratory conditions.

  8. Novel probabilistic models of spatial genetic ancestry with applications to stratification correction in genome-wide association studies.

    PubMed

    Bhaskar, Anand; Javanmard, Adel; Courtade, Thomas A; Tse, David

    2017-03-15

    Genetic variation in human populations is influenced by geographic ancestry due to spatial locality in historical mating and migration patterns. Spatial population structure in genetic datasets has been traditionally analyzed using either model-free algorithms, such as principal components analysis (PCA) and multidimensional scaling, or using explicit spatial probabilistic models of allele frequency evolution. We develop a general probabilistic model and an associated inference algorithm that unify the model-based and data-driven approaches to visualizing and inferring population structure. Our spatial inference algorithm can also be effectively applied to the problem of population stratification in genome-wide association studies (GWAS), where hidden population structure can create fictitious associations when population ancestry is correlated with both the genotype and the trait. Our algorithm Geographic Ancestry Positioning (GAP) relates local genetic distances between samples to their spatial distances, and can be used for visually discerning population structure as well as accurately inferring the spatial origin of individuals on a two-dimensional continuum. On both simulated and several real datasets from diverse human populations, GAP exhibits substantially lower error in reconstructing spatial ancestry coordinates compared to PCA. We also develop an association test that uses the ancestry coordinates inferred by GAP to accurately account for ancestry-induced correlations in GWAS. Based on simulations and analysis of a dataset of 10 metabolic traits measured in a Northern Finland cohort, which is known to exhibit significant population structure, we find that our method has superior power to current approaches. Our software is available at https://github.com/anand-bhaskar/gap . abhaskar@stanford.edu or ajavanma@usc.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  9. Do Age and Sex of School Students Make Significant Difference in Their Multiple Intelligences?

    ERIC Educational Resources Information Center

    Ravi, R.; Vedapriya, S. Gethsi

    2009-01-01

    Multiple Intelligences are a new educational theory proposed by Howard Gardner in 1983. Multiple intelligences describe an array of different kinds of intelligences exhibited by human beings. This theory consists of verbal-linguistic, logical and mathematics, visual and spatial, bodily kinesthetic, musical-rhythmic, intrapersonal, interpersonal,…

  10. Spatial analysis of harmonic oscillation of gypsy moth outbreak intensity

    Treesearch

    Kyle J. Haynes; Andrew M. Liebhold; Derek M. Johnson

    2009-01-01

    Outbreaks of many forest-defoliating insects are synchronous over broad geographic areas and occur with a period of approximately 10 years. Within the range of the gypsy moth in North America, however, there is considerable geographic heterogeneity in strength of periodicity and the frequency of outbreaks. Furthermore, gypsy moth outbreaks exhibit two significant...

  11. Interdependent encoding of pitch, timbre and spatial location in auditory cortex

    PubMed Central

    Bizley, Jennifer K.; Walker, Kerry M. M.; Silverman, Bernard W.; King, Andrew J.; Schnupp, Jan W. H.

    2009-01-01

    Because we can perceive the pitch, timbre and spatial location of a sound source independently, it seems natural to suppose that cortical processing of sounds might separate out spatial from non-spatial attributes. Indeed, recent studies support the existence of anatomically segregated ‘what’ and ‘where’ cortical processing streams. However, few attempts have been made to measure the responses of individual neurons in different cortical fields to sounds that vary simultaneously across spatial and non-spatial dimensions. We recorded responses to artificial vowels presented in virtual acoustic space to investigate the representations of pitch, timbre and sound source azimuth in both core and belt areas of ferret auditory cortex. A variance decomposition technique was used to quantify the way in which altering each parameter changed neural responses. Most units were sensitive to two or more of these stimulus attributes. Whilst indicating that neural encoding of pitch, location and timbre cues is distributed across auditory cortex, significant differences in average neuronal sensitivity were observed across cortical areas and depths, which could form the basis for the segregation of spatial and non-spatial cues at higher cortical levels. Some units exhibited significant non-linear interactions between particular combinations of pitch, timbre and azimuth. These interactions were most pronounced for pitch and timbre and were less commonly observed between spatial and non-spatial attributes. Such non-linearities were most prevalent in primary auditory cortex, although they tended to be small compared with stimulus main effects. PMID:19228960

  12. Spatial and Temporal Coherence of SeaWiFS Chlorophyll Concentration Anomalies in the North Atlantic Bloom (1998-2005) Examined with Giovanni

    NASA Technical Reports Server (NTRS)

    Acker, James G.

    2006-01-01

    The availability of climatological chlorophyll-a concentration data products from the SeaWiFS mission spanning the eight-year mission period allowed the creation of a climatological anomaly analysis function in Giovanni, the GES DISC Interactive Online Visualization and ANalysis Infrastructure. This study utilizes the Giovanni anomaly analysis function to examine mesoscale anomalies in the North Atlantic Ocean during the springtime North Atlantic Bloom. This examination indicates that areas exhibiting positive anomalies and areas exhibiting negative anomalies are coherent over significant spatial scales, with relatively abrupt boundaries between areas with positive and negative anomalies. Year-to-year variability in anomaly "intensity" can be caused by either variability in the temporal occurrence of the bloom peak or by variability in the peak chlorophyll concentration in a particular area. The study will also discuss the feasibility of combining chlorophyll anomaly analysis with other data types.

  13. The spatial learning and memory performance in methamphetamine–sensitized and withdrawn rats

    PubMed Central

    Bigdeli, Imanollah; Asia, Masomeh Nikfarjam- Haft; Miladi-Gorji, Hossein; Fadaei, Atefeh

    2015-01-01

    Objective(s): There is controversial evidence about the effect of methamphetamine (METH) on spatial memory. We tested the time- dependent effects of METH on spatial short-term (working) and long-term (reference) memory in METH –sensitized and withdrawn rats in the Morris water maze. Materials and Methods: Rats were sensitized to METH (2 mg/kg, daily/5 days, SC). Rats were trained in water maze (4 trials/day/for 5 days). Probe test was performed 24 hr after training. Two days after probe test, working memory training (2 trials/day/for 5 days) was conducted. Acquisition–retention interval was 75 min. The treatment was continued per day 30 and 120 min before the test. Two groups of METH –sensitized rats were trained in reference memory after a longer period of withdrawal (30 days). Results: Sensitized rats exhibited significantly longer escape latencies on the training, spent significantly less time in the target zone (all, P<0.05), and their working memory impaired 30 min after injection. While, METH has no effect on the spatial learning process 120 min after injection, and rats spent significantly less time in the target zone (P<0.05), as well it has no effect on working memory. Also, impairment of reference memory persisted after prolonged abstinence. Conclusion: Our findings indicated that METH impaired spatial learning and memory 30 min after injection, but spared spatial learning, either acquisition or retention of spatial working, but partially impaired retention of spatial reference memory following 120 min after injection in sensitized rats, which persisted even after prolonged abstinence. PMID:25945235

  14. Trends and periodicity of daily temperature and precipitation extremes during 1960-2013 in Hunan Province, central south China

    NASA Astrophysics Data System (ADS)

    Chen, Ajiao; He, Xinguang; Guan, Huade; Cai, Yi

    2018-04-01

    In this study, the trends and periodicity in climate extremes are examined in Hunan Province over the period 1960-2013 on the basis of 27 extreme climate indices calculated from daily temperature and precipitation records at 89 meteorological stations. The results show that in the whole province, temperature extremes exhibit a warming trend with more than 50% stations being statistically significant for 7 out of 16 temperature indices, and the nighttime temperature increases faster than the daytime temperature at the annual scale. The changes in most extreme temperature indices show strongly coherent spatial patterns. Moreover, the change rates of almost all temperature indices in north Hunan are greater than those of other regions. However, the statistically significant changes in indices of extreme precipitation are observed at fewer stations than in extreme temperature indices, forming less spatially coherent patterns. Positive trends in indices of extreme precipitation show that the amount and intensity of extreme precipitation events are generally increasing in both annual and seasonal scales, whereas the significant downward trend in consecutive wet days indicates that the precipitation becomes more even over the study period. Analysis of changes in probability distributions of extreme indices for 1960-1986 and 1987-2013 also demonstrates a remarkable shift toward warmer condition and increasing tendency in the amount and intensity of extreme precipitation during the past decades. The variations in extreme climate indices exhibit inconstant frequencies in the wavelet power spectrum. Among the 16 temperature indices, 2 of them show significant 1-year periodic oscillation and 7 of them exhibit significant 4-year cycle during some certain periods. However, significant periodic oscillations can be found in all of the precipitation indices. Wet-day precipitation and three absolute precipitation indices show significant 1-year cycle and other seven provide significant power at the 4-year period, which are mainly found during 1970-1980 and after 1992.

  15. Encouraging Spatial Talk: Using Children's Museums to Bolster Spatial Reasoning

    ERIC Educational Resources Information Center

    Polinsky, Naomi; Perez, Jasmin; Grehl, Mora; McCrink, Koleen

    2017-01-01

    Longitudinal spatial language intervention studies have shown that greater exposure to spatial language improves children's performance on spatial tasks. Can short naturalistic, spatial language interactions also evoke improved spatial performance? In this study, parents were asked to interact with their child at a block wall exhibit in a…

  16. Spatial variation in the bacterial and denitrifying bacterial community in a biofilter treating subsurface agricultural drainage.

    PubMed

    Andrus, J Malia; Porter, Matthew D; Rodríguez, Luis F; Kuehlhorn, Timothy; Cooke, Richard A C; Zhang, Yuanhui; Kent, Angela D; Zilles, Julie L

    2014-02-01

    Denitrifying biofilters can remove agricultural nitrates from subsurface drainage, reducing nitrate pollution that contributes to coastal hypoxic zones. The performance and reliability of natural and engineered systems dependent upon microbially mediated processes, such as the denitrifying biofilters, can be affected by the spatial structure of their microbial communities. Furthermore, our understanding of the relationship between microbial community composition and function is influenced by the spatial distribution of samples.In this study we characterized the spatial structure of bacterial communities in a denitrifying biofilter in central Illinois. Bacterial communities were assessed using automated ribosomal intergenic spacer analysis for bacteria and terminal restriction fragment length polymorphism of nosZ for denitrifying bacteria.Non-metric multidimensional scaling and analysis of similarity (ANOSIM) analyses indicated that bacteria showed statistically significant spatial structure by depth and transect,while denitrifying bacteria did not exhibit significant spatial structure. For determination of spatial patterns, we developed a package of automated functions for the R statistical environment that allows directional analysis of microbial community composition data using either ANOSIM or Mantel statistics.Applying this package to the biofilter data, the flow path correlation range for the bacterial community was 6.4 m at the shallower, periodically in undated depth and 10.7 m at the deeper, continually submerged depth. These spatial structures suggest a strong influence of hydrology on the microbial community composition in these denitrifying biofilters. Understanding such spatial structure can also guide optimal sample collection strategies for microbial community analyses.

  17. Efficient Optical Energy Harvesting in Self-Accelerating Beams

    PubMed Central

    Bongiovanni, Domenico; Hu, Yi; Wetzel, Benjamin; Robles, Raul A.; Mendoza González, Gregorio; Marti-Panameño, Erwin A.; Chen, Zhigang; Morandotti, Roberto

    2015-01-01

    We report the experimental observation of energetically confined self-accelerating optical beams propagating along various convex trajectories. We show that, under an appropriate transverse compression of their spatial spectra, these self-accelerating beams can exhibit a dramatic enhancement of their peak intensity and a significant decrease of their transverse expansion, yet retaining both the expected acceleration profile and the intrinsic self-healing properties. We found our experimental results to be in excellent agreement with the numerical simulations. We expect further applications in such contexts where power budget and optimal spatial confinement can be important limiting factors. PMID:26299360

  18. Quantifying spatially and temporally explicit CO 2 fertilization effects on global terrestrial ecosystem carbon dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Shaoqing; Zhuang, Qianlai; Chen, Min

    Current terrestrial ecosystem models are usually driven with global average annual atmospheric carbon dioxide (CO 2) concentration data at the global scale. However, high-precision CO 2 measurement from eddy flux towers showed that seasonal, spatial surface atmospheric CO 2 concentration differences were as large as 35 ppmv and the site-level tests indicated that the CO 2 variation exhibited different effects on plant photosynthesis. Here we used a process-based ecosystem model driven with two spatially and temporally explicit CO 2 data sets to analyze the atmospheric CO 2 fertilization effects on the global carbon dynamics of terrestrial ecosystems from 2003 tomore » 2010. Our results demonstrated that CO 2 seasonal variation had a negative effect on plant carbon assimilation, while CO2 spatial variation exhibited a positive impact. When both CO 2 seasonal and spatial effects were considered, global gross primary production and net ecosystem production were 1.7 Pg C•yr –1 and 0.08 Pg C•yr –1 higher than the simulation using uniformly distributed CO 2 data set and the difference was significant in tropical and temperate evergreen broadleaf forest regions. Moreover, this study suggests that the CO 2 observation network should be expanded so that the realistic CO 2 variation can be incorporated into the land surface models to adequately account for CO 2 fertilization effects on global terrestrial ecosystem carbon dynamics.« less

  19. Quantifying spatially and temporally explicit CO 2 fertilization effects on global terrestrial ecosystem carbon dynamics

    DOE PAGES

    Liu, Shaoqing; Zhuang, Qianlai; Chen, Min; ...

    2016-07-25

    Current terrestrial ecosystem models are usually driven with global average annual atmospheric carbon dioxide (CO 2) concentration data at the global scale. However, high-precision CO 2 measurement from eddy flux towers showed that seasonal, spatial surface atmospheric CO 2 concentration differences were as large as 35 ppmv and the site-level tests indicated that the CO 2 variation exhibited different effects on plant photosynthesis. Here we used a process-based ecosystem model driven with two spatially and temporally explicit CO 2 data sets to analyze the atmospheric CO 2 fertilization effects on the global carbon dynamics of terrestrial ecosystems from 2003 tomore » 2010. Our results demonstrated that CO 2 seasonal variation had a negative effect on plant carbon assimilation, while CO2 spatial variation exhibited a positive impact. When both CO 2 seasonal and spatial effects were considered, global gross primary production and net ecosystem production were 1.7 Pg C•yr –1 and 0.08 Pg C•yr –1 higher than the simulation using uniformly distributed CO 2 data set and the difference was significant in tropical and temperate evergreen broadleaf forest regions. Moreover, this study suggests that the CO 2 observation network should be expanded so that the realistic CO 2 variation can be incorporated into the land surface models to adequately account for CO 2 fertilization effects on global terrestrial ecosystem carbon dynamics.« less

  20. Hippocampal place cell and inhibitory neuron activity in disrupted-in-schizophrenia-1 mutant mice: implications for working memory deficits

    PubMed Central

    Mesbah-Oskui, Lia; Georgiou, John; Roder, John C

    2015-01-01

    Background: Despite the prevalence of working memory deficits in schizophrenia, the neuronal mechanisms mediating these deficits are not fully understood. Importantly, deficits in spatial working memory are identified in numerous mouse models that exhibit schizophrenia-like endophenotypes. The hippocampus is one of the major brain regions that actively encodes spatial location, possessing pyramidal neurons, commonly referred to as ‘place cells’, that fire in a location-specific manner. This study tests the hypothesis that mice with a schizophrenia-like endophenotype exhibit impaired encoding of spatial location in the hippocampus. Aims: To characterize hippocampal place cell activity in mice that exhibit a schizophrenia-like endophenotype. Methods: We recorded CA1 place cell activity in six control mice and six mice that carry a point mutation in the disrupted-in-schizophrenia-1 gene (Disc1-L100P) and have previously been shown to exhibit deficits in spatial working memory. Results: The spatial specificity and stability of Disc1-L100P place cells were similar to wild-type place cells. Importantly, however, Disc1-L100P place cells exhibited a higher propensity to increase their firing rate in a single, large location of the environment, rather than multiple smaller locations, indicating a generalization in their spatial selectivity. Alterations in the signaling and numbers of CA1 putative inhibitory interneurons and decreased hippocampal theta (5–12 Hz) power were also identified in the Disc1-L100P mice. Conclusions: The generalized spatial selectivity of Disc1-L100P place cells suggests a simplification of the ensemble place codes that encode individual locations and subserve spatial working memory. Moreover, these results suggest that deficient working memory in schizophrenia results from an impaired ability to uniquely code the individual components of a memory sequence. PMID:27280123

  1. Walk, Look, Remember: The Influence of the Gallery's Spatial Layout on Human Memory for an Art Exhibition.

    PubMed

    Krukar, Jakub

    2014-09-01

    The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks.

  2. Walk, Look, Remember: The Influence of the Gallery’s Spatial Layout on Human Memory for an Art Exhibition

    PubMed Central

    Krukar, Jakub

    2014-01-01

    The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks. PMID:25379276

  3. Spatial abilities, Earth science conceptual understanding, and psychological gender of university non-science majors

    NASA Astrophysics Data System (ADS)

    Black, Alice A. (Jill)

    Research has shown the presence of many Earth science misconceptions and conceptual difficulties that may impede concept understanding, and has also identified a number of categories of spatial ability. Although spatial ability has been linked to high performance in science, some researchers believe it has been overlooked in traditional education. Evidence exists that spatial ability can be improved. This correlational study investigated the relationship among Earth science conceptual understanding, three types of spatial ability, and psychological gender, a self-classification that reflects socially-accepted personality and gender traits. A test of Earth science concept understanding, the Earth Science Concepts (ESC) test, was developed and field tested from 2001 to 2003 in 15 sections of university classes. Criterion validity was .60, significant at the .01 level. Spearman/Brown reliability was .74 and Kuder/Richardson reliability was .63. The Purdue Visualization of Rotations (PVOR) (mental rotation), the Group Embedded Figures Test (GEFT) (spatial perception), the Differential Aptitude Test: Space Relations (DAT) (spatial visualization), and the Bem Inventory (BI) (psychological gender) were administered to 97 non-major university students enrolled in undergraduate science classes. Spearman correlations revealed moderately significant correlations at the .01 level between ESC scores and each of the three spatial ability test scores. Stepwise regression analysis indicated that PVOR scores were the best predictor of ESC scores, and showed that spatial ability scores accounted for 27% of the total variation in ESC scores. Spatial test scores were moderately or weakly correlated with each other. No significant correlations were found among BI scores and other test scores. Scantron difficulty analysis of ESC items produced difficulty ratings ranging from 33.04 to 96.43, indicating the percentage of students who answered incorrectly. Mean score on the ESC was 34%, indicating that the non-majors tested exhibited many Earth science misconceptions and conceptual difficulties. A number of significant results were found when independent t-tests and correlations were conducted among test scores and demographic variables. The number of previous university Earth science courses was significantly related to ESC scores. Preservice elementary/middle majors differed significantly in several ways from other non-majors, and several earlier results were not supported. Results of this study indicate that an important opportunity may exist to improve Earth science conceptual understanding by focusing on spatial ability, a cognitive ability that has heretofore not been directly addressed in schools.

  4. Abnormal interactions of verbal- and spatial-memory networks in young people at familial high-risk for schizophrenia.

    PubMed

    Li, Xiaobo; Thermenos, Heidi W; Wu, Ziyan; Momura, Yoko; Wu, Kai; Keshavan, Matcheri; Seidman, Lawrence; DeLisi, Lynn E

    2016-10-01

    Working memory impairment (especially in verbal and spatial domains) is the core neurocognitive impairment in schizophrenia and the familial high-risk (FHR) population. Inconsistent results have been reported in clinical and neuroimaging studies examining the verbal- and spatial-memory deficits in the FHR subjects, due to sample differences and lack of understanding on interactions of the brain regions for processing verbal- and spatial-working memory. Functional MRI data acquired during a verbal- vs. spatial-memory task were included from 51 young adults [26 FHR and 25 controls]. Group comparisons were conducted in brain activation patterns responding to 1) verbal-memory condition (A), 2) spatial-memory condition (B), 3) verbal higher than spatial (A-B), 4) spatial higher than verbal (B-A), 5) conjunction of brain regions that were activated during both A and B (A∧B). Group difference of the laterality index (LI) in inferior frontal lobe for condition A was also assessed. Compared to controls, the FHR group exhibited significantly decreased brain activity in left inferior frontal during A, and significantly stronger involvement of ACC, PCC, paracentral gyrus for the contrast of A-B. The LI showed a trend of reduced left-higher-than-right pattern for verbal-memory processing in the HR group. Our findings suggest that in the entire functional brain network for working-memory processing, verbal information processing associated brain pathways are significantly altered in people at familial high risk for developing schizophrenia. Future studies will need to examine whether these alterations may indicate vulnerability for predicting the onset of Schizophrenia. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Temporal, spatial, and body size effects on growth rates of loggerhead sea turtles (Caretta caretta) in the Northwest Atlantic

    USGS Publications Warehouse

    Bjorndal, Karen A.; Schroeder, Barbara A.; Foley, Allen M.; Witherington, Blair E.; Bresette, Michael; Clark, David; Herren, Richard M.; Arendt, Michael D.; Schmid, Jeffrey R.; Meylan, Anne B.; Meylan, Peter A.; Provancha, Jane A.; Hart, Kristen M.; Lamont, Margaret M.; Carthy, Raymond R.; Bolten, Alan B.

    2013-01-01

    In response to a call from the US National Research Council for research programs to combine their data to improve sea turtle population assessments, we analyzed somatic growth data for Northwest Atlantic (NWA) loggerhead sea turtles (Caretta caretta) from 10 research programs. We assessed growth dynamics over wide ranges of geography (9–33°N latitude), time (1978–2012), and body size (35.4–103.3 cm carapace length). Generalized additive models revealed significant spatial and temporal variation in growth rates and a significant decline in growth rates with increasing body size. Growth was more rapid in waters south of the USA (<24°N) than in USA waters. Growth dynamics in southern waters in the NWA need more study because sample size was small. Within USA waters, the significant spatial effect in growth rates of immature loggerheads did not exhibit a consistent latitudinal trend. Growth rates declined significantly from 1997 through 2007 and then leveled off or increased. During this same interval, annual nest counts in Florida declined by 43 % (Witherington et al. in Ecol Appl 19:30–54, 2009) before rebounding. Whether these simultaneous declines reflect responses in productivity to a common environmental change should be explored to determine whether somatic growth rates can help interpret population trends based on annual counts of nests or nesting females. Because of the significant spatial and temporal variation in growth rates, population models of NWA loggerheads should avoid employing growth data from restricted spatial or temporal coverage to calculate demographic metrics such as age at sexual maturity.

  6. Spatial and temporal variability of hyperspectral signatures of terrain

    NASA Astrophysics Data System (ADS)

    Jones, K. F.; Perovich, D. K.; Koenig, G. G.

    2008-04-01

    Electromagnetic signatures of terrain exhibit significant spatial heterogeneity on a range of scales as well as considerable temporal variability. A statistical characterization of the spatial heterogeneity and spatial scaling algorithms of terrain electromagnetic signatures are required to extrapolate measurements to larger scales. Basic terrain elements including bare soil, grass, deciduous, and coniferous trees were studied in a quasi-laboratory setting using instrumented test sites in Hanover, NH and Yuma, AZ. Observations were made using a visible and near infrared spectroradiometer (350 - 2500 nm) and hyperspectral camera (400 - 1100 nm). Results are reported illustrating: i) several difference scenes; ii) a terrain scene time series sampled over an annual cycle; and iii) the detection of artifacts in scenes. A principal component analysis indicated that the first three principal components typically explained between 90 and 99% of the variance of the 30 to 40-channel hyperspectral images. Higher order principal components of hyperspectral images are useful for detecting artifacts in scenes.

  7. Experiments with central-limit properties of spatial samples from locally covariant random fields

    USGS Publications Warehouse

    Barringer, T.H.; Smith, T.E.

    1992-01-01

    When spatial samples are statistically dependent, the classical estimator of sample-mean standard deviation is well known to be inconsistent. For locally dependent samples, however, consistent estimators of sample-mean standard deviation can be constructed. The present paper investigates the sampling properties of one such estimator, designated as the tau estimator of sample-mean standard deviation. In particular, the asymptotic normality properties of standardized sample means based on tau estimators are studied in terms of computer experiments with simulated sample-mean distributions. The effects of both sample size and dependency levels among samples are examined for various value of tau (denoting the size of the spatial kernel for the estimator). The results suggest that even for small degrees of spatial dependency, the tau estimator exhibits significantly stronger normality properties than does the classical estimator of standardized sample means. ?? 1992.

  8. Effects of spatial coherence in diffraction phase microscopy.

    PubMed

    Edwards, Chris; Bhaduri, Basanta; Nguyen, Tan; Griffin, Benjamin G; Pham, Hoa; Kim, Taewoo; Popescu, Gabriel; Goddard, Lynford L

    2014-03-10

    Quantitative phase imaging systems using white light illumination can exhibit lower noise figures than laser-based systems. However, they can also suffer from object-dependent artifacts, such as halos, which prevent accurate reconstruction of the surface topography. In this work, we show that white light diffraction phase microscopy using a standard halogen lamp can produce accurate height maps of even the most challenging structures provided that there is proper spatial filtering at: 1) the condenser to ensure adequate spatial coherence and 2) the output Fourier plane to produce a uniform reference beam. We explain that these object-dependent artifacts are a high-pass filtering phenomenon, establish design guidelines to reduce the artifacts, and then apply these guidelines to eliminate the halo effect. Since a spatially incoherent source requires significant spatial filtering, the irradiance is lower and proportionally longer exposure times are needed. To circumvent this tradeoff, we demonstrate that a supercontinuum laser, due to its high radiance, can provide accurate measurements with reduced exposure times, allowing for fast dynamic measurements.

  9. Spatial distribution and expression of intracellular and extracellular acid phosphatases of cluster roots at different developmental stages in white lupin.

    PubMed

    Tang, Hongliang; Li, Xiaoqing; Zu, Chao; Zhang, Fusuo; Shen, Jianbo

    2013-09-15

    Acid phosphatases (APases) play a key role in phosphorus (P) acquisition and recycling in plants. White lupin (Lupinus albus L.) forms cluster roots (CRs) and produces large amounts of APases under P deficiency. However, the relationships between the activity of intracellular and extracellular APases (EC 3.1.3.2) and CR development are not fully understood. Here, comparative studies were conducted to examine the spatial variation pattern of APase activity during CR development using the enzyme-labelled fluorescence-97 (ELF-97) and the p-nitrophenyl phosphate methods. The activity of intracellular and extracellular APases was significantly enhanced under P deficiency in the non-CRs and CRs at different developmental stages. These two APases exhibited different spatial distribution patterns during CR development, and these distribution patterns were highly modified by P deficiency. The activity of extracellular APase increased steadily with CR development from meristematic, juvenile, mature to senescent stages under P deficiency. In comparison, P deficiency-induced increase in the activity of intracellular APase remained relatively constant during CR development. Increased activity of intracellular and extracellular APases was associated with enhanced expression of LaSAP1 encoding intracellular APase and LaSAP2 encoding extracellular APase. The expression levels of these two genes were significantly higher at transcriptional level in both mature and senescent CRs. Taken together, these findings demonstrate that both activity and gene expression of intracellular or extracellular APases exhibit a differential response pattern during CR development, depending on root types, CR developmental stages and P supply. Simultaneous in situ determination of intracellular and extracellular APase activity has proved to be an effective approach for studying spatial variation of APases during CR development. Copyright © 2013 Elsevier GmbH. All rights reserved.

  10. The spatial coherence structure of infrasonic waves: analysis of data from International Monitoring System arrays

    NASA Astrophysics Data System (ADS)

    Green, David N.

    2015-04-01

    The spatial coherence structure of 30 infrasound array detections, with source-to-receiver ranges of 25-6500 km, has been measured within the 0.25-1 Hz passband. The data were recorded at International Monitoring System (IMS) microbarograph arrays with apertures of between 1 and 4 km. Such array detections are of interest for Comprehensive Nuclear-Test-Ban Treaty monitoring. The majority of array detections (e.g. 80 per cent of recordings in the third-octave passband centred on 0.63 Hz) exhibit spatial coherence loss anisotropy that is consistent with previous lower frequency atmospheric acoustic studies; coherence loss is more rapid perpendicular to the acoustic propagation direction than parallel to it. The thirty array detections display significant interdetection variation in the magnitude of spatial coherence loss. The measurements can be explained by the simultaneous arrival of wave fronts at the recording array with angular beamwidths of between 0.4 and 7° and velocity bandwidths of between 2 and 40 m s-1. There is a statistically significant positive correlation between source-to-receiver range and the magnitude of coherence loss. Acoustic multipathing generated by interactions with fine-scale wind and temperature gradients along stratospheric propagation paths is qualitatively consistent with the observations. In addition, the study indicates that to isolate coherence loss generated by propagation effects, analysis of signals exhibiting high signal-to-noise ratios (SNR) is required (SNR2 > 11 in this study). The rapid temporal variations in infrasonic noise observed in recordings at IMS arrays indicates that correcting measured coherence values for the effect of noise, using pre-signal estimates of noise power, is ineffective.

  11. Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory

    PubMed Central

    Winkle, Cortney C.; Olsen, Reid H. J.; Kim, Hyojin; Moy, Sheryl S.

    2016-01-01

    During hippocampal development, newly born neurons migrate to appropriate destinations, extend axons, and ramify dendritic arbors to establish functional circuitry. These developmental stages are recapitulated in the dentate gyrus of the adult hippocampus, where neurons are continuously generated and subsequently incorporate into existing, local circuitry. Here we demonstrate that the E3 ubiquitin ligase TRIM9 regulates these developmental stages in embryonic and adult-born mouse hippocampal neurons in vitro and in vivo. Embryonic hippocampal and adult-born dentate granule neurons lacking Trim9 exhibit several morphological defects, including excessive dendritic arborization. Although gross anatomy of the hippocampus was not detectably altered by Trim9 deletion, a significant number of Trim9−/− adult-born dentate neurons localized inappropriately. These morphological and localization defects of hippocampal neurons in Trim9−/− mice were associated with extreme deficits in spatial learning and memory, suggesting that TRIM9-directed neuronal morphogenesis may be involved in hippocampal-dependent behaviors. SIGNIFICANCE STATEMENT Appropriate generation and incorporation of adult-born neurons in the dentate gyrus are critical for spatial learning and memory and other hippocampal functions. Here we identify the brain-enriched E3 ubiquitin ligase TRIM9 as a novel regulator of embryonic and adult hippocampal neuron shape acquisition and hippocampal-dependent behaviors. Genetic deletion of Trim9 elevated dendritic arborization of hippocampal neurons in vitro and in vivo. Adult-born dentate granule cells lacking Trim9 similarly exhibited excessive dendritic arborization and mislocalization of cell bodies in vivo. These cellular defects were associated with severe deficits in spatial learning and memory. PMID:27147649

  12. Perceptual asymmetries in greyscales: object-based versus space-based influences.

    PubMed

    Thomas, Nicole A; Elias, Lorin J

    2012-05-01

    Neurologically normal individuals exhibit leftward spatial biases, resulting from object- and space-based biases; however their relative contributions to the overall bias remain unknown. Relative position within the display has not often been considered, with similar spatial conditions being collapsed across. Study 1 used the greyscales task to investigate the influence of relative position and object- and space-based contributions. One image in each greyscale pair was shifted towards the left or the right. A leftward object-based bias moderated by a bias to the centre was expected. Results confirmed this as a left object-based bias occurred in the right visual field, where the left side of the greyscale pairs was located in the centre visual field. Further, only lower visual field images exhibited a significant left bias in the left visual field. The left bias was also stronger when images were partially overlapping in the right visual field, demonstrating the importance of examining proximity. The second study examined whether object-based biases were stronger when actual objects, with directional lighting biases, were used. Direction of luminosity was congruent or incongruent with spatial location. A stronger object-based bias emerged overall; however a leftward bias was seen in congruent conditions and a rightward bias was seen in incongruent conditions. In conditions with significant biases, the lower visual field image was chosen most often. Results show that object- and space-based biases both contribute; however stimulus type allows either space- or object-based biases to be stronger. A lower visual field bias also interacts with these biases, leading the left bias to be eliminated under certain conditions. The complex interaction occurring between frame of reference and visual field makes spatial location extremely important in determining the strength of the leftward bias. Copyright © 2010 Elsevier Srl. All rights reserved.

  13. Optimization of the Performance of Segmented Scintillators for Radiotherapy Imaging through Novel Binning Techniques

    PubMed Central

    El-Mohri, Youcef; Antonuk, Larry E.; Choroszucha, Richard B.; Zhao, Qihua; Jiang, Hao; Liu, Langechuan

    2014-01-01

    Thick, segmented crystalline scintillators have shown increasing promise as replacement x-ray converters for the phosphor screens currently used in active matrix flat-panel imagers (AMFPIs) in radiotherapy, by virtue of providing over an order of magnitude improvement in the DQE. However, element-to-element misalignment in current segmented scintillator prototypes creates a challenge for optimal registration with underlying AMFPI arrays, resulting in degradation of spatial resolution. To overcome this challenge, a methodology involving the use of a relatively high resolution AMFPI array in combination with novel binning techniques is presented. The array, which has a pixel pitch of 0.127 mm, was coupled to prototype segmented scintillators based on BGO, LYSO and CsI:Tl materials, each having a nominal element-to-element pitch of 1.016 mm and thickness of ~1 cm. The AMFPI systems incorporating these prototypes were characterized at a radiotherapy energy of 6 MV in terms of MTF, NPS, DQE, and reconstructed images of a resolution phantom acquired using a cone-beam CT geometry. For each prototype, the application of 8×8 pixel binning to achieve a sampling pitch of 1.016 mm was optimized through use of an alignment metric which minimized misregistration and thereby improved spatial resolution. In addition, the application of alternative binning techniques that exclude the collection of signal near septal walls resulted in further significant improvement in spatial resolution for the BGO and LYSO prototypes, though not for the CsI:Tl prototype due to the large amount of optical cross-talk resulting from significant light spread between scintillator elements in that device. The efficacy of these techniques for improving spatial resolution appears to be enhanced for scintillator materials that exhibit mechanical hardness, high density and high refractive index, such as BGO. Moreover, materials that exhibit these properties as well as offer significantly higher light output than BGO, such as CdWO4, should provide the additional benefit of preserving DQE performance. PMID:24487347

  14. Hybrid Modeling Approach to Estimate Exposures of Hazardous Air Pollutants (HAPs) for the National Air Toxics Assessment (NATA).

    PubMed

    Scheffe, Richard D; Strum, Madeleine; Phillips, Sharon B; Thurman, James; Eyth, Alison; Fudge, Steve; Morris, Mark; Palma, Ted; Cook, Richard

    2016-11-15

    A hybrid air quality model has been developed and applied to estimate annual concentrations of 40 hazardous air pollutants (HAPs) across the continental United States (CONUS) to support the 2011 calendar year National Air Toxics Assessment (NATA). By combining a chemical transport model (CTM) with a Gaussian dispersion model, both reactive and nonreactive HAPs are accommodated across local to regional spatial scales, through a multiplicative technique designed to improve mass conservation relative to previous additive methods. The broad scope of multiple pollutants capturing regional to local spatial scale patterns across a vast spatial domain is precedent setting within the air toxics community. The hybrid design exhibits improved performance relative to the stand alone CTM and dispersion model. However, model performance varies widely across pollutant categories and quantifiably definitive performance assessments are hampered by a limited observation base and challenged by the multiple physical and chemical attributes of HAPs. Formaldehyde and acetaldehyde are the dominant HAP concentration and cancer risk drivers, characterized by strong regional signals associated with naturally emitted carbonyl precursors enhanced in urban transport corridors with strong mobile source sector emissions. The multiple pollutant emission characteristics of combustion dominated source sectors creates largely similar concentration patterns across the majority of HAPs. However, reactive carbonyls exhibit significantly less spatial variability relative to nonreactive HAPs across the CONUS.

  15. Multiple paternity and sporophytic inbreeding depression in a dioicous moss species.

    PubMed

    Szövényi, P; Ricca, M; Shaw, A J

    2009-11-01

    Multiple paternity (polyandry) frequently occurs in flowering plants and animals and is assumed to have an important function in the evolution of reproductive traits. Polyandry in bryophytes may occur among multiple sporophytes of a female gametophyte; however, its occurrence and extent is unknown. In this study we investigate the occurrence and extent of multiple paternity, spatial genetic structure, and sporophytic inbreeding depression in natural populations of a dioicous bryophyte species, Sphagnum lescurii, using microsatellite markers. Multiple paternity is prevalent among sporophytes of a female gametophyte and male genotypes exhibit significant skew in paternity. Despite significant spatial genetic structure in the population, suggesting frequent inbreeding, the number of inbred and outbred sporophytes was balanced, resulting in an average fixation coefficient and population level selfing rate of zero. In line with the prediction of sporophytic inbreeding depression sporophyte size was significantly correlated with the level of heterozygosity. Furthermore, female gametophytes preferentially supported sporophytes with higher heterozygosity. These results indicate that polyandry provides the opportunity for postfertilization selection in bryophytes having short fertilization distances and spatially structured populations facilitating inbreeding. Preferential maternal support of the more heterozygous sporophytes suggests active inbreeding avoidance that may have significant implications for mating system evolution in bryophytes.

  16. Nd:AlN polycrystalline ceramics: A candidate media for tunable, high energy, near IR lasers

    NASA Astrophysics Data System (ADS)

    Wieg, A. T.; Grossnickle, M. J.; Kodera, Y.; Gabor, N. M.; Garay, J. E.

    2016-09-01

    We present processing and characterization of Nd-doped aluminum nitride (Nd:AlN) polycrystalline ceramics. We compare ceramics with significant segregation of Nd to those exhibiting minimal segregation. Spatially resolved photoluminescence maps reveal a strong correlation between homogeneous Nd doping and spatially homogeneous light emission. The spectroscopically resolved light emission lines show excellent agreement with the expected Nd electronic transitions. Notably, the lines are significantly broadened, producing near IR emission (˜1077 nm) with a remarkable ˜100 nm bandwidth at room temperature. We attribute the broadened lines to a combination of effects: multiple Nd-sites, anisotropy of AlN and phonon broadening. These broadened, overlapping lines in a media with excellent thermal conductivity have potential for Nd-based, tunable lasers with high average power.

  17. Endogenous spatial attention: evidence for intact functioning in adults with autism

    PubMed Central

    Grubb, Michael A.; Behrmann, Marlene; Egan, Ryan; Minshew, Nancy J.; Carrasco, Marisa; Heeger, David J.

    2012-01-01

    Lay Abstract Attention allows us to selectively process the vast amount of information with which we are confronted. Focusing on a certain location of the visual scene (visual spatial attention) enables the prioritization of some aspects of information while ignoring others. Rapid manipulation of the attention field (i.e., the location and spread of visual spatial attention) is a critical aspect of human cognition, and previous research on spatial attention in individuals with autism spectrum disorders (ASD) has produced inconsistent results. In a series of three experiments, we evaluated claims in the literature that individuals with ASD exhibit a deficit in voluntarily controlling the deployment and size of the spatial attention field. We measured how well participants perform a visual discrimination task (accuracy) and how quickly they do so (reaction time), with and without spatial uncertainty (i.e., the lack of predictability concerning the spatial position of the upcoming stimulus). We found that high–functioning adults with autism exhibited slower reactions times overall with spatial uncertainty, but the effects of attention on performance accuracies and reaction times were indistinguishable between individuals with autism and typically developing individuals, in all three experiments. These results provide evidence of intact endogenous spatial attention function in high–functioning adults with ASD, suggesting that atypical endogenous spatial attention cannot be a latent characteristic of autism in general. Scientific Abstract Rapid manipulation of the attention field (i.e., the location and spread of visual spatial attention) is a critical aspect of human cognition, and previous research on spatial attention in individuals with autism spectrum disorders (ASD) has produced inconsistent results. In a series of three psychophysical experiments, we evaluated claims in the literature that individuals with ASD exhibit a deficit in voluntarily controlling the deployment and size of the spatial attention field. We measured the spatial distribution of performance accuracies and reaction times to quantify the sizes and locations of the attention field, with and without spatial uncertainty (i.e., the lack of predictability concerning the spatial position of the upcoming stimulus). We found that high–functioning adults with autism exhibited slower reactions times overall with spatial uncertainty, but the effects of attention on performance accuracies and reaction times were indistinguishable between individuals with autism and typically developing individuals, in all three experiments. These results provide evidence of intact endogenous spatial attention function in high–functioning adults with ASD, suggesting that atypical endogenous attention cannot be a latent characteristic of autism in general. PMID:23427075

  18. Age-related changes in rostral basal forebrain cholinergic and GABAergic projection neurons: Relationship with spatial impairment

    PubMed Central

    Bañuelos, C.; LaSarge, C. L.; McQuail, J. A.; Hartman, J. J.; Gilbert, R. J.; Ormerod, B. K.; Bizon, J. L.

    2013-01-01

    Both cholinergic and GABAergic projections from the rostral basal forebrain have been implicated in hippocampal function and mnemonic abilities. While dysfunction of cholinergic neurons has been heavily implicated in age-related memory decline, significantly less is known regarding how age-related changes in co-distributed GABAergic projection neurons contribute to a decline in hippocampal-dependent spatial learning. In the current study, confocal stereology was used to quantify cholinergic (choline acetyltransferase (ChAT) immunopositive) neurons, GABAergic projection (glutamic decarboxylase 67 (GAD67) immunopositive) neurons, and total (NeuN immunopositive) neurons in the rostral basal forebrain of young and aged rats that were first characterized on a spatial learning task. ChAT immunopositive neurons were significantly but modestly reduced in aged rats. Although ChAT immunopositive neuron number was strongly correlated with spatial learning abilities among young rats, the reduction of ChAT immunopositive neurons was not associated with impaired spatial learning in aged rats. In contrast, the number of GAD67 immunopositive neurons was robustly and selectively elevated in aged rats that exhibited impaired spatial learning. Interestingly, the total number of rostral basal forebrain neurons was comparable in young and aged rats, regardless of their cognitive status. These data demonstrate differential effects of age on phenotypically distinct rostral basal forebrain projection neurons, and implicate dysregulated cholinergic and GABAergic septohippocampal circuitry in age-related mnemonic decline. PMID:22817834

  19. Microbes on mountainsides: Contrasting elevational patterns of bacterial and plant diversity

    PubMed Central

    Bryant, Jessica A.; Lamanna, Christine; Morlon, Hélène; Kerkhoff, Andrew J.; Enquist, Brian J.; Green, Jessica L.

    2008-01-01

    The study of elevational diversity gradients dates back to the foundation of biogeography. Although elevational patterns of plant and animal diversity have been studied for centuries, such patterns have not been reported for microorganisms and remain poorly understood. Here, in an effort to assess the generality of elevational diversity patterns, we examined soil bacterial and plant diversity along an elevation gradient. To gain insight into the forces that structure these patterns, we adopted a multifaceted approach to incorporate information about the structure, diversity, and spatial turnover of montane communities in a phylogenetic context. We found that observed patterns of plant and bacterial diversity were fundamentally different. While bacterial taxon richness and phylogenetic diversity decreased monotonically from the lowest to highest elevations, plants followed a unimodal pattern, with a peak in richness and phylogenetic diversity at mid-elevations. At all elevations bacterial communities had a tendency to be phylogenetically clustered, containing closely related taxa. In contrast, plant communities did not exhibit a uniform phylogenetic structure across the gradient: they became more overdispersed with increasing elevation, containing distantly related taxa. Finally, a metric of phylogenetic beta-diversity showed that bacterial lineages were not randomly distributed, but rather exhibited significant spatial structure across the gradient, whereas plant lineages did not exhibit a significant phylogenetic signal. Quantifying the influence of sample scale in intertaxonomic comparisons remains a challenge. Nevertheless, our findings suggest that the forces structuring microorganism and macroorganism communities along elevational gradients differ. PMID:18695215

  20. Spatial-temporal and cancer risk assessment of selected hazardous air pollutants in Seattle.

    PubMed

    Wu, Chang-fu; Liu, L-J Sally; Cullen, Alison; Westberg, Hal; Williamson, John

    2011-01-01

    In the Seattle Air Toxics Monitoring Pilot Program, we measured 15 hazardous air pollutants (HAPs) at 6 sites for more than a year between 2000 and 2002. Spatial-temporal variations were evaluated with random-effects models and principal component analyses. The potential health risks were further estimated based on the monitored data, with the incorporation of the bootstrapping technique for the uncertainty analysis. It is found that the temporal variability was generally higher than the spatial variability for most air toxics. The highest temporal variability was observed for tetrachloroethylene (70% temporal vs. 34% spatial variability). Nevertheless, most air toxics still exhibited significant spatial variations, even after accounting for the temporal effects. These results suggest that it would require operating multiple air toxics monitoring sites over a significant period of time with proper monitoring frequency to better evaluate population exposure to HAPs. The median values of the estimated inhalation cancer risks ranged between 4.3 × 10⁻⁵ and 6.0 × 10⁻⁵, with the 5th and 95th percentile levels exceeding the 1 in a million level. VOCs as a whole contributed over 80% of the risk among the HAPs measured and arsenic contributed most substantially to the overall risk associated with metals. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. The effect of inlet boundary conditions in image-based CFD modeling of aortic flow

    NASA Astrophysics Data System (ADS)

    Madhavan, Sudharsan; Kemmerling, Erica Cherry

    2016-11-01

    CFD of cardiovascular flow is a growing and useful field, but simulations are subject to a number of sources of uncertainty which must be quantified. Our work focuses on the uncertainty introduced by the selection of inlet boundary conditions in an image-based, patient-specific model of the aorta. Specifically, we examined the differences between plug flow, fully developed parabolic flow, linear shear flows, skewed parabolic flow profiles, and Womersley flow. Only the shape of the inlet velocity profile was varied-all other parameters were held constant between simulations, including the physiologically realistic inlet flow rate waveform and outlet flow resistance. We found that flow solutions with different inlet conditions did not exhibit significant differences beyond 1 . 75 inlet diameters from the aortic root. Time averaged wall shear stress (TAWSS) was also calculated. The linear shear velocity boundary condition solution exhibited the highest spatially averaged TAWSS, about 2 . 5 % higher than the fully developed parabolic velocity boundary condition, which had the lowest spatially averaged TAWSS.

  2. Efficient anharmonic vibrational spectroscopy for large molecules using local-mode coordinates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, Xiaolu; Steele, Ryan P., E-mail: ryan.steele@utah.edu

    This article presents a general computational approach for efficient simulations of anharmonic vibrational spectra in chemical systems. An automated local-mode vibrational approach is presented, which borrows techniques from localized molecular orbitals in electronic structure theory. This approach generates spatially localized vibrational modes, in contrast to the delocalization exhibited by canonical normal modes. The method is rigorously tested across a series of chemical systems, ranging from small molecules to large water clusters and a protonated dipeptide. It is interfaced with exact, grid-based approaches, as well as vibrational self-consistent field methods. Most significantly, this new set of reference coordinates exhibits a well-behavedmore » spatial decay of mode couplings, which allows for a systematic, a priori truncation of mode couplings and increased computational efficiency. Convergence can typically be reached by including modes within only about 4 Å. The local nature of this truncation suggests particular promise for the ab initio simulation of anharmonic vibrational motion in large systems, where connection to experimental spectra is currently most challenging.« less

  3. Evaluation of Simulated Clinical Breast Exam Motion Patterns Using Marker-Less Video Tracking

    PubMed Central

    Azari, David P.; Pugh, Carla M.; Laufer, Shlomi; Kwan, Calvin; Chen, Chia-Hsiung; Yen, Thomas Y.; Hu, Yu Hen; Radwin, Robert G.

    2016-01-01

    Objective This study investigates using marker-less video tracking to evaluate hands-on clinical skills during simulated clinical breast examinations (CBEs). Background There are currently no standardized and widely accepted CBE screening techniques. Methods Experienced physicians attending a national conference conducted simulated CBEs presenting different pathologies with distinct tumorous lesions. Single hand exam motion was recorded and analyzed using marker-less video tracking. Four kinematic measures were developed to describe temporal (time pressing and time searching) and spatial (area covered and distance explored) patterns. Results Mean differences between time pressing, area covered, and distance explored varied across the simulated lesions. Exams were objectively categorized as either sporadic, localized, thorough, or efficient for both temporal and spatial categories based on spatiotemporal characteristics. The majority of trials were temporally or spatially thorough (78% and 91%), exhibiting proportionally greater time pressing and time searching (temporally thorough) and greater area probed with greater distance explored (spatially thorough). More efficient exams exhibited proportionally more time pressing with less time searching (temporally efficient) and greater area probed with less distance explored (spatially efficient). Just two (5.9 %) of the trials exhibited both high temporal and spatial efficiency. Conclusions Marker-less video tracking was used to discriminate different examination techniques and measure when an exam changes from general searching to specific probing. The majority of participants exhibited more thorough than efficient patterns. Application Marker-less video kinematic tracking may be useful for quantifying clinical skills for training and assessment. PMID:26546381

  4. Space-time patterns of trends in stratospheric constituents derived from UARS measurements

    NASA Astrophysics Data System (ADS)

    Randel, William J.; Wu, Fei; Russell, James M.; Waters, Joe

    1999-02-01

    The spatial and temporal behavior of low-frequency changes (trends) in stratospheric constituents measured by instruments on the Upper Atmosphere Research Satellite (UARS) during 1991-98 is investigated. The data include CH4, H2O, HF, HCl, O3, and NO2 from the Halogen Occultation Experiment (HALOE), and O3, ClO, and HNO3 from the Microwave Limb Sounder (MLS). Time series of global anomalies are analyzed by linear regression and empirical orthogonal function analysis. Each of the constituents show significant linear trends over at least some region of the stratosphere, and the spatial patterns exhibit coupling between the different species. Several of the constituents (namely CH4, H2O, HF, HCl, O3, and NO2) exhibit a temporal change in trend rates, with strong changes prior to 1996 and weaker (or reversed) trends thereafter. Positive trends are observed in upper stratospheric ClO, with a percentage rate during 1993-97 consistent with stratospheric HCl increases and with tropospheric chlorine emission rates. Significant negative trends in ozone in the tropical middle stratosphere are found in both HALOE and MLS data during 1993-97, together with positive trends in the tropics near 25 km. These trends are very different from the decadal-scale ozone trends observed since 1979, and this demonstrates the variability of trends calculated over short time periods. Positive trends in NO2 are found in the tropical middle stratosphere, and spatial coincidence to the observed ozone decreases suggests the ozone is responding to the NO2 increase. Significant negative trends in HNO3 are found in the lower stratosphere of both hemispheres. These coupled signatures offer a fingerprint of chemical evolution in the stratosphere for the UARS time frame.

  5. Characteristics of temperature change in China over the last 2000 years and spatial patterns of dryness/wetness during cold and warm periods

    NASA Astrophysics Data System (ADS)

    Ge, Quansheng; Liu, Haolong; Ma, Xiang; Zheng, Jingyun; Hao, Zhixin

    2017-08-01

    This paper presents new high-resolution proxies and paleoclimatic reconstructions for studying climate changes in China for the past 2000 years. Multi-proxy synthesized reconstructions show that temperature variation in China has exhibited significant 50-70-yr, 100-120-yr, and 200-250-yr cycles. Results also show that the amplitudes of decadal and centennial temperature variation were 1.3°C and 0.7°C, respectively, with the latter significantly correlated with long-term changes in solar radiation, especially cold periods, which correspond approximately to sunspot minima. The most rapid warming in China occurred over AD 1870-2000, at a rate of 0.56° ± 0.42°C (100 yr)-1; however, temperatures recorded in the 20th century may not be unprecedented for the last 2000 years, as data show records for the periods AD 981-1100 and AD 1201-70 are comparable to the present. The ensemble means of dryness/wetness spatial patterns in eastern China across all centennial warm periods illustrate a tripole pattern: dry south of 25°N, wet from 25°-30°N, and dry to the north of 30°N. However, for all centennial cold periods, this spatial pattern also exhibits a meridional distribution. The increase in precipitation over the monsoonal regions of China associated with the 20th century warming can primarily be attributed to a mega El Ni˜no-Southern Oscillation and the Atlantic Multidecadal Oscillation. In addition, a significant association between increasing numbers of locusts and dry/cold conditions is found in eastern China. Plague intensity also generally increases in concert with wetness in northern China, while more precipitation is likely to have a negative effect in southern China.

  6. Global-scale modes of surface temperature variability on interannual to century timescales

    NASA Technical Reports Server (NTRS)

    Mann, Michael E.; Park, Jeffrey

    1994-01-01

    Using 100 years of global temperature anomaly data, we have performed a singluar value decomposition of temperature variations in narrow frequency bands to isolate coherent spatio-temporal modes of global climate variability. Statistical significance is determined from confidence limits obtained by Monte Carlo simulations. Secular variance is dominated by a globally coherent trend; with nearly all grid points warming in phase at varying amplitude. A smaller, but significant, share of the secular variance corresponds to a pattern dominated by warming and subsequent cooling in the high latitude North Atlantic with a roughly centennial timescale. Spatial patterns associated with significant peaks in variance within a broad period range from 2.8 to 5.7 years exhibit characteristic El Nino-Southern Oscillation (ENSO) patterns. A recent transition to a regime of higher ENSO frequency is suggested by our analysis. An interdecadal mode in the 15-to-18 years period and a mode centered at 7-to-8 years period both exhibit predominantly a North Atlantic Oscillation (NAO) temperature pattern. A potentially significant decadal mode centered on 11-to-12 years period also exhibits an NAO temperature pattern and may be modulated by the century-scale North Atlantic variability.

  7. Hippocampus-dependent spatial memory impairment due to molar tooth loss is ameliorated by an enriched environment.

    PubMed

    Kondo, Hiroko; Kurahashi, Minori; Mori, Daisuke; Iinuma, Mitsuo; Tamura, Yasuo; Mizutani, Kenmei; Shimpo, Kan; Sonoda, Shigeru; Azuma, Kagaku; Kubo, Kin-ya

    2016-01-01

    Teeth are crucial, not only for mastication, but for overall nutrition and general health, including cognitive function. Aged mice with chronic stress due to tooth loss exhibit impaired hippocampus-dependent learning and memory. Exposure to an enriched environment restores the reduced hippocampal function. Here, we explored the effects of an enriched environment on learning deficits and hippocampal morphologic changes in aged senescence-accelerated mouse strain P8 (SAMP8) mice with tooth loss. Eight-month-old male aged SAMP8 mice with molar intact or with molars removed were housed in either a standard environment or enriched environment for 3 weeks. The Morris water maze was performed for spatial memory test. The newborn cell proliferation, survival, and differentiation in the hippocampus were analyzed using 5-Bromodeoxyuridine (BrdU) immunohistochemical method. The hippocampal brain-derived neurotrophic factor (BDNF) levels were also measured. Mice with upper molars removed (molarless) exhibited a significant decline in the proliferation and survival of newborn cells in the dentate gyrus (DG) as well as in hippocampal BDNF levels. In addition, neuronal differentiation of newly generated cells was suppressed and hippocampus-dependent spatial memory was impaired. Exposure of molarless mice to an enriched environment attenuated the reductions in the hippocampal BDNF levels and neuronal differentiation, and partially improved the proliferation and survival of newborn cells, as well as the spatial memory ability. These findings indicated that an enriched environment could ameliorate the hippocampus-dependent spatial memory impairment induced by molar tooth loss. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Spatial gradient for unique-feature detection in patients with unilateral neglect: evidence from auditory and visual search.

    PubMed

    Eramudugolla, Ranmalee; Mattingley, Jason B

    2008-01-01

    Patients with unilateral spatial neglect following right hemisphere damage are impaired in detecting contralesional targets in both visual and haptic search tasks, and often show a graded improvement in detection performance for more ipsilesional spatial locations. In audition, multiple simultaneous sounds are most effectively perceived if they are distributed along the frequency dimension. Thus, attention to spectro-temporal features alone can allow detection of a target sound amongst multiple simultaneous distracter sounds, regardless of whether these sounds are spatially separated. Spatial bias in attention associated with neglect should not affect auditory search based on spectro-temporal features of a sound target. We report that a right brain damaged patient with neglect demonstrated a significant gradient favouring the ipsilesional side on a visual search task as well as an auditory search task in which the target was a frequency modulated tone amongst steady distractor tones. No such asymmetry was apparent in the auditory search performance of a control patient with a right hemisphere lesion but no neglect. The results suggest that the spatial bias in attention exhibited by neglect patients affects stimulus processing even when spatial information is irrelevant to the task.

  9. Spatial Variability of the Topsoil Organic Carbon in the Moso Bamboo Forests of Southern China in Association with Soil Properties

    PubMed Central

    Zhang, Houxi; Zhuang, Shunyao; Qian, Haiyan; Wang, Feng; Ji, Haibao

    2015-01-01

    Understanding the spatial variability of soil organic carbon (SOC) must be enhanced to improve sampling design and to develop soil management strategies in terrestrial ecosystems. Moso bamboo (Phyllostachys pubescens Mazel ex Houz.) forests have a high SOC storage potential; however, they also vary significantly spatially. This study investigated the spatial variability of SOC (0-20 cm) in association with other soil properties and with spatial variables in the Moso bamboo forests of Jian’ou City, which is a typical bamboo hometown in China. 209 soil samples were collected from Moso bamboo stands and then analyzed for SOC, bulk density (BD), pH, cation exchange capacity (CEC), and gravel content (GC) based on spatial distribution. The spatial variability of SOC was then examined using geostatistics. A Kriging map was produced through ordinary interpolation and required sample numbers were calculated by classical and Kriging methods. An aggregated boosted tree (ABT) analysis was also conducted. A semivariogram analysis indicated that ln(SOC) was best fitted with an exponential model and that it exhibited moderate spatial dependence, with a nugget/sill ratio of 0.462. SOC was significantly and linearly correlated with BD (r = −0.373**), pH (r = −0.429**), GC (r = −0.163*), CEC (r = 0.263**), and elevation (r = 0.192**). Moreover, the Kriging method requires fewer samples than the classical method given an expected standard error level as per a variance analysis. ABT analysis indicated that the physicochemical variables of soil affected SOC variation more significantly than spatial variables did, thus suggesting that the SOC in Moso bamboo forests can be strongly influenced by management practices. Thus, this study provides valuable information in relation to sampling strategy and insight into the potential of adjustments in agronomic measure, such as in fertilization for Moso bamboo production. PMID:25789615

  10. Children with Chromosome 22q11.2 Deletion Syndrome Exhibit Impaired Spatial Working Memory

    ERIC Educational Resources Information Center

    Wong, Ling M.; Riggins, Tracy; Harvey, Danielle; Cabaral, Margarita; Simon, Tony J.

    2014-01-01

    Individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS) have been shown to have impairments in processing spatiotemporal information. The authors examined whether children with 22q11.2DS exhibit impairments in spatial working memory performance due to these weaknesses, even when controlling for maintenance of attention. Children with…

  11. Data on amyloid precursor protein accumulation, spontaneous physical activity, and motor learning after traumatic brain injury in the triple-transgenic mouse model of Alzheimer׳s disease.

    PubMed

    Kishimoto, Yasushi; Shishido, Hajime; Sawanishi, Mayumi; Toyota, Yasunori; Ueno, Masaki; Kubota, Takashi; Kirino, Yutaka; Tamiya, Takashi; Kawai, Nobuyuki

    2016-12-01

    This data article contains supporting information regarding the research article entitled "Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer׳s disease" (H. Shishido, Y. Kishimoto, N. Kawai, Y. Toyota, M. Ueno, T. Kubota, Y. Kirino, T. Tamiya, 2016) [1]. Triple-transgenic (3×Tg)-Alzheimer׳s disease (AD) model mice exhibited significantly poorer spatial learning than sham-treated 3×Tg-AD mice 28 days after traumatic brain injury (TBI). Correspondingly, amyloid-β (Aβ) deposition within the hippocampus was significantly greater in 3×Tg-AD mice 28 days after TBI. However, data regarding the short-term and long-term influences of TBI on amyloid precursor protein (APP) accumulation in AD model mice remain limited. Furthermore, there is little data showing whether physical activity and motor learning are affected by TBI in AD model mice. Here, we provide immunocytochemistry data confirming that TBI induces significant increases in APP accumulation in 3×Tg-AD mice at both 7 days and 28 days after TBI. Furthermore, 3×Tg-AD model mice exhibit a reduced ability to acquire conditioned responses (CRs) during delay eyeblink conditioning compared to sham-treated 3×Tg-AD model mice 28 days after TBI. However, physical activity and motor performance are not significantly changed in TBI-treated 3×Tg-AD model mice.

  12. Single-photon-level quantum image memory based on cold atomic ensembles

    PubMed Central

    Ding, Dong-Sheng; Zhou, Zhi-Yuan; Shi, Bao-Sen; Guo, Guang-Can

    2013-01-01

    A quantum memory is a key component for quantum networks, which will enable the distribution of quantum information. Its successful development requires storage of single-photon light. Encoding photons with spatial shape through higher-dimensional states significantly increases their information-carrying capability and network capacity. However, constructing such quantum memories is challenging. Here we report the first experimental realization of a true single-photon-carrying orbital angular momentum stored via electromagnetically induced transparency in a cold atomic ensemble. Our experiments show that the non-classical pair correlation between trigger photon and retrieved photon is retained, and the spatial structure of input and retrieved photons exhibits strong similarity. More importantly, we demonstrate that single-photon coherence is preserved during storage. The ability to store spatial structure at the single-photon level opens the possibility for high-dimensional quantum memories. PMID:24084711

  13. Spatial analysis of ecosystem service relationships to improve targeting of payments for hydrological services

    PubMed Central

    Manson, Robert H.; Ricketts, Taylor H.; Geissert, Daniel

    2018-01-01

    Payment for hydrological services (PHS) are popular tools for conserving ecosystems and their water-related services. However, improving the spatial targeting and impacts of PHS, as well as their ability to foster synergies with other ecosystem services (ES), remain challenging. We aimed at using spatial analyses to evaluate the targeting performance of México’s National PHS program in central Veracruz. We quantified the effectiveness of areas targeted for PHS in actually covering areas of high HS provision and social priority during 2003–2013. First, we quantified provisioning and spatial distributions of two target (water yield and soil retention), and one non-target ES (carbon storage) using InVEST. Subsequently, pairwise relationships among ES were quantified by using spatial correlation and overlap analyses. Finally, we evaluated targeting by: (i) prioritizing areas of individual and overlapping ES; (ii) quantifying spatial co-occurrences of these priority areas with those targeted by PHS; (iii) evaluating the extent to which PHS directly contribute to HS delivery; and (iv), testing if PHS targeted areas disproportionately covered areas with high ecological and social priority. We found that modelled priority areas exhibited non-random distributions and distinct spatial patterns. Our results show significant pairwise correlations between all ES suggesting synergistic relationships. However, our analysis showed a significantly lower overlap than expected and thus significant mismatches between PHS targeted areas and all types of priority areas. These findings suggest that the targeting of areas with high HS provisioning and social priority by Mexico’s PHS program could be improved significantly. This study underscores: (1) the importance of using maps of HS provisioning as main targeting criteria in PHS design to channel payments towards areas that require future conservation, and (2) the need for future research that helps balance ecological and socioeconomic targeting criteria. PMID:29462205

  14. Abnormal Neural Network of Primary Insomnia: Evidence from Spatial Working Memory Task fMRI.

    PubMed

    Li, Yongli; Liu, Liya; Wang, Enfeng; Zhang, Hongju; Dou, Shewei; Tong, Li; Cheng, Jingliang; Chen, Chuanliang; Shi, Dapeng

    2016-01-01

    Contemporary functional MRI (fMRI) methods can provide a wealth of information about the neural mechanisms associated with primary insomnia (PI), which centrally involve neural network circuits related to spatial working memory. A total of 30 participants diagnosed with PI and without atypical brain anatomy were selected along with 30 age- and gender-matched healthy controls. Subjects were administered the Pittsburgh Sleep Quality Index (PSQI), Hamilton Rating Scale for Depression and clinical assessments of spatial working memory, followed by an MRI scan and fMRI in spatial memory task state. Statistically significant differences between PSQI and spatial working memory were observed between PI patients and controls (p < 0.01). Activation of neural networks related to spatial memory task state in the PI group was observed at the left temporal lobe, left occipital lobe and right frontal lobe. Lower levels of activation were observed in the left parahippocampal gyrus, right parahippocampal gyrus, bilateral temporal cortex, frontal cortex and superior parietal lobule. Participants with PI exhibited characteristic abnormalities in the neural network connectivity related to spatial working memory. These results may be indicative of an underlying pathological mechanism related to spatial working memory deterioration in PI, analogous to recently described mechanisms in other mental health disorders. © 2016 S. Karger AG, Basel.

  15. Temporal-spatial evolution of the hydrologic drought characteristics of the karst drainage basins in South China

    NASA Astrophysics Data System (ADS)

    He, Zhonghua; Liang, Hong; Yang, Chaohui; Huang, Fasu; Zeng, Xinbo

    2018-02-01

    Hydrologic drought, as a typical natural phenomenon in the context of global climate change, is the extension and development of meteorological and agricultural droughts, and it is an eventual and extreme drought. This study selects 55 hydrological control basins in Southern China as research areas. The study analyzes features, such as intensity and occurrence frequency of hydrologic droughts, and explores the spatial-temporal evolution patterns in the karst drainage basins in Southern China by virtue of Streamflow Drought Index. Results show that (1) the general hydrologic droughts from 1970s to 2010s exhibited ;an upward trend after having experienced a previous decline; in the karst drainage basins in Southern China; the trend was mainly represented by the gradual alleviation of hydrologic droughts from 1970s to 1990s and the gradual aggravation from 2000s to 2010s. (2) The spatial-temporal evolution pattern of occurrence frequency in the karst drainage basins in Southern China was consistent with the intensity of hydrologic droughts. The periods of 1970s and 2010s exhibited the highest occurrence frequency. (3) The karst drainage basins in Southern China experienced extremely complex variability of hydrologic droughts from 1970s to 2010s. Drought intensity and occurrence frequency significantly vary for different types of hydrology.

  16. ENSO related variability in the Southern Hemisphere, 1948-2000

    NASA Astrophysics Data System (ADS)

    Ribera, Pedro; Mann, Michael E.

    2003-01-01

    The spatiotemporal evolution of Southern Hemisphere climate variability is diagnosed based on the use of the NCEP reanalysis (1948-2000) dataset. Using the MTM-SVD analysis method, significant narrowband variability is isolated from the multi-variate dataset. It is found that the ENSO signal exhibits statistically significant behavior at quasiquadrennial (3-6 yr) timescales for the full time-period. A significant quasibiennial (2-3 yr) timescales emerges only for the latter half of period. Analyses of the spatial evolution of the two reconstructed signals shed additional light on linkages between low and high-latitude Southern Hemisphere climate anomalies.

  17. Cultural background shapes spatial reference frame proclivity

    PubMed Central

    Goeke, Caspar; Kornpetpanee, Suchada; Köster, Moritz; Fernández-Revelles, Andrés B.; Gramann, Klaus; König, Peter

    2015-01-01

    Spatial navigation is an essential human skill that is influenced by several factors. The present study investigates how gender, age, and cultural background account for differences in reference frame proclivity and performance in a virtual navigation task. Using an online navigation study, we recorded reaction times, error rates (confusion of turning axis), and reference frame proclivity (egocentric vs. allocentric reference frame) of 1823 participants. Reaction times significantly varied with gender and age, but were only marginally influenced by the cultural background of participants. Error rates were in line with these results and exhibited a significant influence of gender and culture, but not age. Participants’ cultural background significantly influenced reference frame selection; the majority of North-Americans preferred an allocentric strategy, while Latin-Americans preferred an egocentric navigation strategy. European and Asian groups were in between these two extremes. Neither the factor of age nor the factor of gender had a direct impact on participants’ navigation strategies. The strong effects of cultural background on navigation strategies without the influence of gender or age underlines the importance of socialized spatial cognitive processes and argues for socio-economic analysis in studies investigating human navigation. PMID:26073656

  18. A Special Extract of Bacopa monnieri (CDRI-08) Restores Learning and Memory by Upregulating Expression of the NMDA Receptor Subunit GluN2B in the Brain of Scopolamine-Induced Amnesic Mice

    PubMed Central

    Rai, Rakesh; Singh, Hemant K.; Prasad, S.

    2015-01-01

    In the present communication, we have investigated effects of the CDRI-08, a well characterized extract of Bacopa monnieri, on expression of the GluN2B subunit of NMDAR in various brain regions of the scopolamine-induced amnesic mice. Our behavioral data reveal that scopolamine-treated amnesic mice exhibit significant decline in the spatial memory compared to the normal control mice. Our RT-PCR and immunoblotting data revealed that the scopolamine treatment resulted in a significant downregulation of the NMDAR GluN2B subunit expression in prefrontal cortex and hippocampus. Our enzyme assay data revealed that scopolamine caused a significant increase in the acetylcholinesterase activity in both the brain regions. Further, oral administration of the CDRI-08 to scopolamine-treated amnesic mice restored the spatial memory which was found to be associated with significant upregulation of the GluN2B subunit expression and decline in the acetylcholinesterase activity in prefrontal cortex as well as hippocampus towards their levels in the normal control mice. Our study provides the evidence for the mechanism underlying role of the Bacopa monnieri extract (CDRI-08) in restoring spatial memory in amnesic mice, which may have therapeutic implications. PMID:26413117

  19. Evaluating the Consistency of the 1982–1999 NDVI Trends in the Iberian Peninsula across Four Time-series Derived from the AVHRR Sensor: LTDR, GIMMS, FASIR, and PAL-II

    PubMed Central

    Alcaraz-Segura, Domingo; Liras, Elisa; Tabik, Siham; Paruelo, José; Cabello, Javier

    2010-01-01

    Successive efforts have processed the Advanced Very High Resolution Radiometer (AVHRR) sensor archive to produce Normalized Difference Vegetation Index (NDVI) datasets (i.e., PAL, FASIR, GIMMS, and LTDR) under different corrections and processing schemes. Since NDVI datasets are used to evaluate carbon gains, differences among them may affect nations’ carbon budgets in meeting international targets (such as the Kyoto Protocol). This study addresses the consistency across AVHRR NDVI datasets in the Iberian Peninsula (Spain and Portugal) by evaluating whether their 1982–1999 NDVI trends show similar spatial patterns. Significant trends were calculated with the seasonal Mann-Kendall trend test and their spatial consistency with partial Mantel tests. Over 23% of the Peninsula (N, E, and central mountain ranges) showed positive and significant NDVI trends across the four datasets and an additional 18% across three datasets. In 20% of Iberia (SW quadrant), the four datasets exhibited an absence of significant trends and an additional 22% across three datasets. Significant NDVI decreases were scarce (croplands in the Guadalquivir and Segura basins, La Mancha plains, and Valencia). Spatial consistency of significant trends across at least three datasets was observed in 83% of the Peninsula, but it decreased to 47% when comparing across the four datasets. FASIR, PAL, and LTDR were the most spatially similar datasets, while GIMMS was the most different. The different performance of each AVHRR dataset to detect significant NDVI trends (e.g., LTDR detected greater significant trends (both positive and negative) and in 32% more pixels than GIMMS) has great implications to evaluate carbon budgets. The lack of spatial consistency across NDVI datasets derived from the same AVHRR sensor archive, makes it advisable to evaluate carbon gains trends using several satellite datasets and, whether possible, independent/additional data sources to contrast. PMID:22205868

  20. Evaluating the consistency of the 1982-1999 NDVI trends in the Iberian Peninsula across four time-series derived from the AVHRR sensor: LTDR, GIMMS, FASIR, and PAL-II.

    PubMed

    Alcaraz-Segura, Domingo; Liras, Elisa; Tabik, Siham; Paruelo, José; Cabello, Javier

    2010-01-01

    Successive efforts have processed the Advanced Very High Resolution Radiometer (AVHRR) sensor archive to produce Normalized Difference Vegetation Index (NDVI) datasets (i.e., PAL, FASIR, GIMMS, and LTDR) under different corrections and processing schemes. Since NDVI datasets are used to evaluate carbon gains, differences among them may affect nations' carbon budgets in meeting international targets (such as the Kyoto Protocol). This study addresses the consistency across AVHRR NDVI datasets in the Iberian Peninsula (Spain and Portugal) by evaluating whether their 1982-1999 NDVI trends show similar spatial patterns. Significant trends were calculated with the seasonal Mann-Kendall trend test and their spatial consistency with partial Mantel tests. Over 23% of the Peninsula (N, E, and central mountain ranges) showed positive and significant NDVI trends across the four datasets and an additional 18% across three datasets. In 20% of Iberia (SW quadrant), the four datasets exhibited an absence of significant trends and an additional 22% across three datasets. Significant NDVI decreases were scarce (croplands in the Guadalquivir and Segura basins, La Mancha plains, and Valencia). Spatial consistency of significant trends across at least three datasets was observed in 83% of the Peninsula, but it decreased to 47% when comparing across the four datasets. FASIR, PAL, and LTDR were the most spatially similar datasets, while GIMMS was the most different. The different performance of each AVHRR dataset to detect significant NDVI trends (e.g., LTDR detected greater significant trends (both positive and negative) and in 32% more pixels than GIMMS) has great implications to evaluate carbon budgets. The lack of spatial consistency across NDVI datasets derived from the same AVHRR sensor archive, makes it advisable to evaluate carbon gains trends using several satellite datasets and, whether possible, independent/additional data sources to contrast.

  1. Simultaneous multiview capture and fusion improves spatial resolution in wide-field and light-sheet microscopy

    PubMed Central

    Wu, Yicong; Chandris, Panagiotis; Winter, Peter W.; Kim, Edward Y.; Jaumouillé, Valentin; Kumar, Abhishek; Guo, Min; Leung, Jacqueline M.; Smith, Corey; Rey-Suarez, Ivan; Liu, Huafeng; Waterman, Clare M.; Ramamurthi, Kumaran S.; La Riviere, Patrick J.; Shroff, Hari

    2016-01-01

    Most fluorescence microscopes are inefficient, collecting only a small fraction of the emitted light at any instant. Besides wasting valuable signal, this inefficiency also reduces spatial resolution and causes imaging volumes to exhibit significant resolution anisotropy. We describe microscopic and computational techniques that address these problems by simultaneously capturing and subsequently fusing and deconvolving multiple specimen views. Unlike previous methods that serially capture multiple views, our approach improves spatial resolution without introducing any additional illumination dose or compromising temporal resolution relative to conventional imaging. When applying our methods to single-view wide-field or dual-view light-sheet microscopy, we achieve a twofold improvement in volumetric resolution (~235 nm × 235 nm × 340 nm) as demonstrated on a variety of samples including microtubules in Toxoplasma gondii, SpoVM in sporulating Bacillus subtilis, and multiple protein distributions and organelles in eukaryotic cells. In every case, spatial resolution is improved with no drawback by harnessing previously unused fluorescence. PMID:27761486

  2. Regional inequalities in premature mortality in Great Britain

    PubMed Central

    Laroze, Denise; Neumayer, Eric

    2018-01-01

    Premature mortality exhibits strong spatial patterns in Great Britain. Local authorities that are located further North and West, that are more distant from its political centre London and that are more urban tend to have a higher premature mortality rate. Premature mortality also tends to cluster among geographically contiguous and proximate local authorities. We develop a novel analytical research design that relies on spatial pattern recognition to demonstrate that an empirical model that contains only socio-economic variables can eliminate these spatial patterns almost entirely. We demonstrate that socioeconomic factors across local authority districts explain 81 percent of variation in female and 86 percent of variation in male premature mortality in 2012–14. As our findings suggest, policy-makers cannot hope that health policies alone suffice to significantly reduce inequalities in health. Rather, it requires strong efforts to reduce the inequalities in socio-economic factors, or living conditions for short, in order to overcome the spatial disparities in health, of which premature mortality is a clear indication. PMID:29489918

  3. Responses of infaunal populations to benthoscape structure and the potential importance of transition zones

    USGS Publications Warehouse

    Zajac, R.N.; Lewis, R.S.; Poppe, L.J.; Twichell, D.C.; Vozarik, J.; DiGiacomo-Cohen, M. L.

    2003-01-01

    Relationships between population abundance and seafloor landscape, or benthoscape, structure were examined for 16 infaunal taxa in eastern Long Island Sound. Based on analyses of a side-scan sonar mosaic, the 19.4-km2 study area was comprised of six distinct large-scale (> km2) benthoscape elements, with varying levels of mesoscale (km2-m2) and small-scale (2) physical and biological habitat heterogeneity. Transition zones among elements varied from ~50 to 200 m in width, comprised ~32% of the benthoscape, and added to overall benthoscape heterogeneity. Population abundances of nine taxa varied significantly among the large-scale elements. Most species were found at high abundances only in one benthoscape element, but three had several foci of elevated abundances. Analyses of population responses to habitat heterogeneity at different spatial scales indicated that abundances of eight taxa varied significantly among spatial scales, but the significant scales were mixed among these species. Relatively large residual variations suggest significant amounts of mesoscale spatial variation were unaccounted for, varying from ~1 km2 to several m2. Responses to transition zones were mixed as well. Abundances of nine taxa varied significantly among transition zones and interiors of benthoscape elements, most with elevated abundances in transition zones. Our results show that infaunal populations exhibit complex and spatially varying patterns of abundance in relation to benthoscape structure and suggest that mesoscale variation may be particularly critical in this regard. Also, transition zones among benthoscape features add considerably to this variation and may be ecological important areas in seafloor environments.

  4. Visuo-spatial cueing in children with differential reading and spelling profiles

    PubMed Central

    Kemény, Ferenc; Gangl, Melanie; Schulte-Körne, Gerd; Moll, Kristina; Landerl, Karin

    2017-01-01

    Dyslexia has been claimed to be causally related to deficits in visuo-spatial attention. In particular, inefficient shifting of visual attention during spatial cueing paradigms is assumed to be associated with problems in graphemic parsing during sublexical reading. The current study investigated visuo-spatial attention performance in an exogenous cueing paradigm in a large sample (N = 191) of third and fourth graders with different reading and spelling profiles (controls, isolated reading deficit, isolated spelling deficit, combined deficit in reading and spelling). Once individual variability in reaction times was taken into account by means of z-transformation, a cueing deficit (i.e. no significant difference between valid and invalid trials) was found for children with combined deficits in reading and spelling. However, poor readers without spelling problems showed a cueing effect comparable to controls, but exhibited a particularly strong right-over-left advantage (position effect). Isolated poor spellers showed a significant cueing effect, but no position effect. While we replicated earlier findings of a reduced cueing effect among poor nonword readers (indicating deficits in sublexical processing), we also found a reduced cueing effect among children with particularly poor orthographic spelling (indicating deficits in lexical processing). Thus, earlier claims of a specific association with nonword reading could not be confirmed. Controlling for ADHD-symptoms reported in a parental questionnaire did not impact on the statistical analysis, indicating that cueing deficits are not caused by more general attentional limitations. Between 31 and 48% of participants in the three reading and/or spelling deficit groups as well as 32% of the control group showed reduced spatial cueing. These findings indicate a significant, but moderate association between certain aspects of visuo-spatial attention and subcomponents of written language processing, the causal status of which is yet unclear. PMID:28686635

  5. Visuo-spatial cueing in children with differential reading and spelling profiles.

    PubMed

    Banfi, Chiara; Kemény, Ferenc; Gangl, Melanie; Schulte-Körne, Gerd; Moll, Kristina; Landerl, Karin

    2017-01-01

    Dyslexia has been claimed to be causally related to deficits in visuo-spatial attention. In particular, inefficient shifting of visual attention during spatial cueing paradigms is assumed to be associated with problems in graphemic parsing during sublexical reading. The current study investigated visuo-spatial attention performance in an exogenous cueing paradigm in a large sample (N = 191) of third and fourth graders with different reading and spelling profiles (controls, isolated reading deficit, isolated spelling deficit, combined deficit in reading and spelling). Once individual variability in reaction times was taken into account by means of z-transformation, a cueing deficit (i.e. no significant difference between valid and invalid trials) was found for children with combined deficits in reading and spelling. However, poor readers without spelling problems showed a cueing effect comparable to controls, but exhibited a particularly strong right-over-left advantage (position effect). Isolated poor spellers showed a significant cueing effect, but no position effect. While we replicated earlier findings of a reduced cueing effect among poor nonword readers (indicating deficits in sublexical processing), we also found a reduced cueing effect among children with particularly poor orthographic spelling (indicating deficits in lexical processing). Thus, earlier claims of a specific association with nonword reading could not be confirmed. Controlling for ADHD-symptoms reported in a parental questionnaire did not impact on the statistical analysis, indicating that cueing deficits are not caused by more general attentional limitations. Between 31 and 48% of participants in the three reading and/or spelling deficit groups as well as 32% of the control group showed reduced spatial cueing. These findings indicate a significant, but moderate association between certain aspects of visuo-spatial attention and subcomponents of written language processing, the causal status of which is yet unclear.

  6. Overview of Initial Results from CRISM

    NASA Astrophysics Data System (ADS)

    Seelos, F.; Murchie, S.; Mustard, J.; Pelkey, S.; Roach, L.; Elhmann, B.; Arvidson, R.; Wiseman, S.; Milliken, R.; CRISM Team

    2007-05-01

    The Mars Reconnaissance Orbiter (MRO) reached 100 days of primary science phase operations on February 15th, 2007. Over this time period, the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) has acquired high spatial resolution hyperspectral observations and contextual multispectral survey data of type localities that record water-rock interaction through much of the geologic history of Mars. CRISM's primary science objectives are to characterize the mineralogical record of past aqueous environments and to monitor the contemporary spatial and seasonal distributions of volatiles in the surface-atmosphere system. These objectives are accomplished through an observation strategy that includes targeted data acquisition, atmospheric and seasonal monitoring, and global mapping. Targeted observations are acquired by gimbaling the instrument along-track to reduce apparent ground motion, resulting in a spatial resolution of 15-20 m/pixel in 544 wavelengths from 362 to 3920 nm. As a part of each targeted observation 10 additional spatially binned images are acquired at different atmospheric path lengths, creating an emission phase function (EPF) that allows surface-atmosphere separation in the analysis of the observed radiance. The atmospheric and seasonal monitoring campaigns consist of global grids of EPF measurements at regular Ls intervals. In CRISM's global mapping campaign, data are acquired in a push broom observing mode at a reduced spatial and spectral resolution of 200m/pxl and 72 selected spectral channels. Initial data analysis reveals evidence for environmental variability throughout Martian history. Noachian deposits exhibit diverse phyllosilicate mineralogy in a greater number of geologic units than previously recognized. Distinct mineralogic signatures are sometimes separated only by hundreds of meters, indicating variability in alteration environment or parent rock composition. Hesperian layered deposits exhibit strong vertical heterogeneity with different abundances and types of sulfate minerals, suggesting local environmental changes on short geologic timescales. The Amazonian north polar layered deposits exhibit complex vertical layering in the abundance and/or grain size of water ice. The underlying basal unit shows little evidence for ice except in restricted locations where the morphology is consistent with subsequent modification of the deposits by fluid flow. Multispectral mapping is nearly complete at the high northern latitudes and shows evidence for significant hydrated mineral content in portions of the basal unit.

  7. Spatial accuracy of a simplified disaggregation method for traffic emissions applied in seven mid-sized Chilean cities

    NASA Astrophysics Data System (ADS)

    Ossés de Eicker, Margarita; Zah, Rainer; Triviño, Rubén; Hurni, Hans

    The spatial accuracy of top-down traffic emission inventory maps obtained with a simplified disaggregation method based on street density was assessed in seven mid-sized Chilean cities. Each top-down emission inventory map was compared against a reference, namely a more accurate bottom-up emission inventory map from the same study area. The comparison was carried out using a combination of numerical indicators and visual interpretation. Statistically significant differences were found between the seven cities with regard to the spatial accuracy of their top-down emission inventory maps. In compact cities with a simple street network and a single center, a good accuracy of the spatial distribution of emissions was achieved with correlation values>0.8 with respect to the bottom-up emission inventory of reference. In contrast, the simplified disaggregation method is not suitable for complex cities consisting of interconnected nuclei, resulting in correlation values<0.5. Although top-down disaggregation of traffic emissions generally exhibits low accuracy, the accuracy is significantly higher in compact cities and might be further improved by applying a correction factor for the city center. Therefore, the method can be used by local environmental authorities in cities with limited resources and with little knowledge on the pollution situation to get an overview on the spatial distribution of the emissions generated by traffic activities.

  8. Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China.

    PubMed

    Yu, Gui-Rui; Zhu, Xian-Jin; Fu, Yu-Ling; He, Hong-Lin; Wang, Qiu-Feng; Wen, Xue-Fa; Li, Xuan-Ran; Zhang, Lei-Ming; Zhang, Li; Su, Wen; Li, Sheng-Gong; Sun, Xiao-Min; Zhang, Yi-Ping; Zhang, Jun-Hui; Yan, Jun-Hua; Wang, Hui-Min; Zhou, Guang-Sheng; Jia, Bing-Rui; Xiang, Wen-Hua; Li, Ying-Nian; Zhao, Liang; Wang, Yan-Fen; Shi, Pei-Li; Chen, Shi-Ping; Xin, Xiao-Ping; Zhao, Feng-Hua; Wang, Yu-Ying; Tong, Cheng-Li

    2013-03-01

    Understanding the dynamics and underlying mechanism of carbon exchange between terrestrial ecosystems and the atmosphere is one of the key issues in global change research. In this study, we quantified the carbon fluxes in different terrestrial ecosystems in China, and analyzed their spatial variation and environmental drivers based on the long-term observation data of ChinaFLUX sites and the published data from other flux sites in China. The results indicate that gross ecosystem productivity (GEP), ecosystem respiration (ER), and net ecosystem productivity (NEP) of terrestrial ecosystems in China showed a significantly latitudinal pattern, declining linearly with the increase of latitude. However, GEP, ER, and NEP did not present a clear longitudinal pattern. The carbon sink functional areas of terrestrial ecosystems in China were mainly located in the subtropical and temperate forests, coastal wetlands in eastern China, the temperate meadow steppe in the northeast China, and the alpine meadow in eastern edge of Qinghai-Tibetan Plateau. The forest ecosystems had stronger carbon sink than grassland ecosystems. The spatial patterns of GEP and ER in China were mainly determined by mean annual precipitation (MAP) and mean annual temperature (MAT), whereas the spatial variation in NEP was largely explained by MAT. The combined effects of MAT and MAP explained 79%, 62%, and 66% of the spatial variations in GEP, ER, and NEP, respectively. The GEP, ER, and NEP in different ecosystems in China exhibited 'positive coupling correlation' in their spatial patterns. Both ER and NEP were significantly correlated with GEP, with 68% of the per-unit GEP contributed to ER and 29% to NEP. MAT and MAP affected the spatial patterns of ER and NEP mainly by their direct effects on the spatial pattern of GEP. © 2012 Blackwell Publishing Ltd.

  9. Soil moisture dynamics and dominant controls at different spatial scales over semiarid and semi-humid areas

    NASA Astrophysics Data System (ADS)

    Suo, Lizhu; Huang, Mingbin; Zhang, Yongkun; Duan, Liangxia; Shan, Yan

    2018-07-01

    Soil moisture dynamics plays an active role in ecological and hydrological processes, and it depends on a large number of environmental factors, such as topographic attributes, soil properties, land use types, and precipitation. However, studies must still clarify the relative significance of these environmental factors at different soil depths and at different spatial scales. This study aimed: (1) to characterize temporal and spatial variations in soil moisture content (SMC) at four soil layers (0-40, 40-100, 100-200, and 200-500 cm) and three spatial scales (plot, hillslope, and region); and (2) to determine their dominant controls in diverse soil layers at different spatial scales over semiarid and semi-humid areas of the Loess Plateau, China. Given the high co-dependence of environmental factors, partial least squares regression (PLSR) was used to detect relative significance among 15 selected environmental factors that affect SMC. Temporal variation in SMC decreased with increasing soil depth, and vertical changes in the 0-500 cm soil profile were divided into a fast-changing layer (0-40 cm), an active layer (40-100 cm), a sub-active layer (100-200 cm), and a relatively stable layer (200-500 cm). PLSR models simulated SMC accurately in diverse soil layers at different scales; almost all values for variation in response (R2) and goodness of prediction (Q2) were >0.5 and >0.0975, respectively. Upper and lower layer SMCs were the two most important factors that influenced diverse soil layers at three scales, and these SMC variables exhibited the highest importance in projection (VIP) values. The 7-day antecedent precipitation and 7-day antecedent potential evapotranspiration contributed significantly to SMC only at the 0-40 cm soil layer. VIP of soil properties, especially sand and silt content, which influenced SMC strongly, increased significantly after increasing the measured scale. Mean annual precipitation and potential evapotranspiration also influenced SMC at the regional scale significantly. Overall, this study indicated that dominant controls of SMC varied among three spatial scales on the Loess Plateau, and VIP was a function of spatial scale and soil depth.

  10. The Influence of Visual Experience on the Ability to Form Spatial Mental Models Based on Route and Survey Descriptions

    ERIC Educational Resources Information Center

    Noordzij, Matthijs L.; Zuidhoek, Sander; Postma, Albert

    2006-01-01

    The purpose of the present study is twofold: the first objective is to evaluate the importance of visual experience for the ability to form a spatial representation (spatial mental model) of fairly elaborate spatial descriptions. Secondly, we examine whether blind people exhibit the same preferences (i.e. level of performance on spatial tasks) as…

  11. Prognostic significance of inverse spatial QRS-T angle circadian pattern in myocardial infarction survivors.

    PubMed

    Giannopoulos, Georgios; Dilaveris, Polychronis; Batchvarov, Velislav; Synetos, Andreas; Hnatkova, Katerina; Gatzoulis, Konstantinos; Malik, Marek; Stefanadis, Christodoulos

    2009-01-01

    We investigated the predictive value of the spatial QRS-T angle (QRSTA) circadian variation in myocardial infarction (MI) patients. Analyzing 24-hour recordings (SEER MC, GE Marquette) from 151 MI patients (age 63 +/- 12.7), the QRSTA was computed in derived XYZ leads. QRS-T angle values were compared between daytime and night time. The end point was cardiac death or life-threatening ventricular arrhythmia in 1 year. Overall, QRSTA was slightly higher during the day vs. the night (91 degrees vs. 87 degrees, P = .005). However, 33.8% of the patients showed an inverse diurnal QRSTA variation (higher values at night), which was correlated to the outcome (P = .001, odds ratio 6.7). In multivariate analysis, after entering all factors exhibiting univariate trend towards significance, inverse QRSTA circadian pattern remained significant (P = .036). Inverse QRSTA circadian pattern was found to be associated with adverse outcome (22.4%) in MI patients, whereas a normal pattern was associated (96%) with a favorable outcome.

  12. Geography of breast cancer incidence according to age & birth cohorts.

    PubMed

    Gregorio, David I; Ford, Chandler; Samociuk, Holly

    2017-06-01

    Geographic variation in breast cancer incidence across Connecticut was examined according to age and birth cohort -specific groups. We assigned each of 60,937 incident breast cancer cases diagnosed in Connecticut, 1986-2009, to one of 828 census tracts around the state. Global and local spatial statistics estimated rate variation across the state according to age and birth cohorts. We found the global distribution of incidence rates across places to be more heterogeneous for younger women and later birth cohorts. Concurrently, the spatial scan identified more locations with significantly high rates that pertained to larger proportions of at-risk women within these groups. Geographic variation by age groups was more pronounced than by birth cohorts. Geographic patterns of cancer incidence exhibit differences within and across age and birth cohorts. With the continued insights from descriptive epidemiology, our capacity to effectively limit spatial disparities in cancer will improve. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1☆

    PubMed Central

    Li, Yuhong; Shi, Changhua; Lu, Guobing; Xu, Qian; Liu, Shaochen

    2012-01-01

    In this study, we investigated the effects of mobile phone radiation on spatial learning, reference memory, and morphology in related brain regions. After the near-field radiation (0.52–1.08 W/kg) was delivered to 8-week-old Wistar rats 2 hours per day for 1 month, behavioral changes were examined using the Morris water maze. Compared with the sham-irradiated rats, the irradiated rats exhibited impaired performance. Morphological changes were investigated by examining synaptic ultrastructural changes in the hippocampus. Using the physical dissector technique, the number of pyramidal neurons, the synaptic profiles, and the length of postsynaptic densities in the CA1 region were quantified stereologically. The morphological changes included mitochondrial degenerations, fewer synapses, and shorter postsynaptic densities in the radiated rats. These findings indicate that mobile phone radiation can significantly impair spatial learning and reference memory and induce morphological changes in the hippocampal CA1 region. PMID:25709623

  14. Complex Dynamics of Wetland Ecosystem with Nonlinear Harvesting: Application to Chilika Lake in Odisha, India

    NASA Astrophysics Data System (ADS)

    Upadhyay, Ranjit Kumar; Tiwari, S. K.; Roy, Parimita

    2015-06-01

    In this paper, an attempt has been made to study the spatial and temporal dynamical interactions among the species of wetland ecosystem through a mathematical model. The model represents the population dynamics of phytoplankton, zooplankton and fish species found in Chilika lake, Odisha, India. Nonlinear stability analysis of both the temporal and spatial models has been carried out. Maximum sustainable yield and optimal harvesting policy have been studied for a nonspatial model system. Numerical simulation has been performed to figure out the parameters responsible for the complex dynamics of the wetland system. Significant outcomes of our numerical findings and their interpretations from an ecological point of view are provided in this paper. Numerical simulation of spatial model exhibits some interesting and beautiful patterns. We have also pointed out the parameters that are responsible for the good health of wetland ecosystem.

  15. Spatial and temporal variability of microgeographic genetic structure in white-tailed deer

    USGS Publications Warehouse

    Scribner, Kim T.; Smith, Michael H.; Chesser, Ronald K.

    1997-01-01

    Techniques are described that define contiguous genetic subpopulations of white-tailed deer (Odocoileus virginianus) based on the spatial dispersion of 4,749 individuals that possessed discrete character values (alleles or genotypes) during each of 6 years (1974-1979). White-tailed deer were not uniformly distributed in space, but exhibited considerable spatial genetic structuring. Significant non-random clusters of individuals were documented during each year based on specific alleles and genotypes at the Sdh locus. Considerable temporal variation was observed in the position and genetic composition of specific clusters, which reflected changes in allele frequency in small geographic areas. The position of clusters did not consistently correspond with traditional management boundaries based on major discontinuities in habitat (swamp versus upland) and hunt compartments that were defined by roads and streams. Spatio-temporal stability of observed genetic contiguous clusters was interpreted relative to method and intensity of harvest, movements, and breeding ecology.

  16. Spatially resolved mapping of electrical conductivity across individual domain (grain) boundaries in graphene.

    PubMed

    Clark, Kendal W; Zhang, X-G; Vlassiouk, Ivan V; He, Guowei; Feenstra, Randall M; Li, An-Ping

    2013-09-24

    All large-scale graphene films contain extended topological defects dividing graphene into domains or grains. Here, we spatially map electronic transport near specific domain and grain boundaries in both epitaxial graphene grown on SiC and CVD graphene on Cu subsequently transferred to a SiO2 substrate, with one-to-one correspondence to boundary structures. Boundaries coinciding with the substrate step on SiC exhibit a significant potential barrier for electron transport of epitaxial graphene due to the reduced charge transfer from the substrate near the step edge. Moreover, monolayer-bilayer boundaries exhibit a high resistance that can change depending on the height of substrate step coinciding at the boundary. In CVD graphene, the resistance of a grain boundary changes with the width of the disordered transition region between adjacent grains. A quantitative modeling of boundary resistance reveals the increased electron Fermi wave vector within the boundary region, possibly due to boundary induced charge density variation. Understanding how resistance change with domain (grain) boundary structure in graphene is a crucial first step for controlled engineering of defects in large-scale graphene films.

  17. Clutch size variation in Tawny Owls (Strix aluco) from adjacent valley systems: can this be used as a surrogate to investigate temporal and spatial variations in vole density?

    Treesearch

    Steve J. Petty; Billy L. Fawkes

    1997-01-01

    Research on Tawny Owls (Strix aluco) in Kielder Forest, northern England, since 1981 demonstrated that field voles (Microtus agrestis) were their most important food. Here, field voles exhibited a 3-4 year cycle of abundance, and mean clutch size in Tawny Owls was significantly related to vole abundance in March. In this analysis...

  18. Ditch network sustains functional connectivity and influences patterns of gene flow in an intensive agricultural landscape

    PubMed Central

    Favre-Bac, L; Mony, C; Ernoult, A; Burel, F; Arnaud, J-F

    2016-01-01

    In intensive agricultural landscapes, plant species previously relying on semi-natural habitats may persist as metapopulations within landscape linear elements. Maintenance of populations' connectivity through pollen and seed dispersal is a key factor in species persistence in the face of substantial habitat loss. The goals of this study were to investigate the potential corridor role of ditches and to identify the landscape components that significantly impact patterns of gene flow among remnant populations. Using microsatellite loci, we explored the spatial genetic structure of two hydrochorous wetland plants exhibiting contrasting local abundance and different habitat requirements: the rare and regionally protected Oenanthe aquatica and the more commonly distributed Lycopus europaeus, in an 83 km2 agricultural lowland located in northern France. Both species exhibited a significant spatial genetic structure, along with substantial levels of genetic differentiation, especially for L. europaeus, which also expressed high levels of inbreeding. Isolation-by-distance analysis revealed enhanced gene flow along ditches, indicating their key role in effective seed and pollen dispersal. Our data also suggested that the configuration of the ditch network and the landscape elements significantly affected population genetic structure, with (i) species-specific scale effects on the genetic neighborhood and (ii) detrimental impact of human ditch management on genetic diversity, especially for O. aquatica. Altogether, these findings highlighted the key role of ditches in the maintenance of plant biodiversity in intensive agricultural landscapes with few remnant wetland habitats. PMID:26486611

  19. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.

    PubMed

    Velazquez, Ramon; Ash, Jessica A; Powers, Brian E; Kelley, Christy M; Strawderman, Myla; Luscher, Zoe I; Ginsberg, Stephen D; Mufson, Elliott J; Strupp, Barbara J

    2013-10-01

    In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer's disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypocellularity evident in fetuses and children with DS. A murine model of DS and AD (the Ts65Dn mouse) exhibits key features of these disorders, notably deficient ontogenetic neurogenesis, degeneration of basal forebrain cholinergic neurons (BFCNs), and cognitive deficits. Adult hippocampal (HP) neurogenesis is also deficient in Ts65Dn mice and may contribute to the observed cognitive dysfunction. Herein, we demonstrate that supplementing the maternal diet with additional choline (approximately 4.5 times the amount in normal rodent chow) dramatically improved the performance of the adult trisomic offspring in a radial arm water maze task. Ts65Dn offspring of choline-supplemented dams performed significantly better than unsupplemented Ts65Dn mice. Furthermore, adult hippocampal neurogenesis was partially normalized in the maternal choline supplemented (MCS) trisomic offspring relative to their unsupplemented counterparts. A significant correlation was observed between adult hippocampal neurogenesis and performance in the water maze, suggesting that the increased neurogenesis seen in the supplemented trisomic mice contributed functionally to their improved spatial cognition. These findings suggest that supplementing the maternal diet with additional choline has significant translational potential for DS. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

    PubMed Central

    Velazquez, Ramon; Ash, Jessica A.; Powers, Brian E.; Kelley, Christy M.; Strawderman, Myla; Luscher, Zoe I.; Ginsberg, Stephen D.; Mufson, Elliott J.; Strupp, Barbara J.

    2014-01-01

    In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer’s disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypocellularity evident in fetuses and children with DS. A murine model of DS and AD (the Ts65Dn mouse) exhibits key features of these disorders, notably deficient ontogenetic neurogenesis, degeneration of basal forebrain cholinergic neurons (BFCNs), and cognitive deficits. Adult hippocampal (HP) neurogenesis is also deficient in Ts65Dn mice and may contribute to the observed cognitive dysfunction. Herein, we demonstrate that supplementing the maternal diet with additional choline (approximately 4.5 times the amount in normal rodent chow) dramatically improved the performance of the adult trisomic offspring in a radial arm water maze task. Ts65Dn offspring of choline-supplemented dams performed significantly better than unsupplemented Ts65Dn mice. Furthermore, adult hippocampal neurogenesis was partially normalized in the maternal choline supplemented (MCS) trisomic offspring relative to their unsupplemented counterparts. A significant correlation was observed between adult hippocampal neurogenesis and performance in the water maze, suggesting that the increased neurogenesis seen in the supplemented trisomic mice contributed functionally to their improved spatial cognition. These findings suggest that supplementing the maternal diet with additional choline has significant translational potential for DS. PMID:23643842

  1. Motivational valence alters memory formation without altering exploration of a real-life spatial environment.

    PubMed

    Chiew, Kimberly S; Hashemi, Jordan; Gans, Lee K; Lerebours, Laura; Clement, Nathaniel J; Vu, Mai-Anh T; Sapiro, Guillermo; Heller, Nicole E; Adcock, R Alison

    2018-01-01

    Volitional exploration and learning are key to adaptive behavior, yet their characterization remains a complex problem for cognitive science. Exploration has been posited as a mechanism by which motivation promotes memory, but this relationship is not well-understood, in part because novel stimuli that motivate exploration also reliably elicit changes in neuromodulatory brain systems that directly alter memory formation, via effects on neural plasticity. To deconfound interrelationships between motivation, exploration, and memory formation we manipulated motivational state prior to entering a spatial context, measured exploratory responses to the context and novel stimuli within it, and then examined motivation and exploration as predictors of memory outcomes. To elicit spontaneous exploration, we used the physical space of an art exhibit with affectively rich content; we expected motivated exploration and memory to reflect multiple factors, including not only motivational valence, but also individual differences. Motivation was manipulated via an introductory statement framing exhibit themes in terms of Promotion- or Prevention-oriented goals. Participants explored the exhibit while being tracked by video. They returned 24 hours later for recall and spatial memory tests, followed by measures of motivation, personality, and relevant attitude variables. Promotion and Prevention condition participants did not differ in terms of group-level exploration time or memory metrics, suggesting similar motivation to explore under both framing contexts. However, exploratory behavior and memory outcomes were significantly more closely related under Promotion than Prevention, indicating that Prevention framing disrupted expected depth-of-encoding effects. Additionally, while trait measures predicted exploration similarly across framing conditions, traits interacted with motivational framing context and facial affect to predict memory outcomes. This novel characterization of motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments.

  2. Motivational valence alters memory formation without altering exploration of a real-life spatial environment

    PubMed Central

    Hashemi, Jordan; Gans, Lee K.; Lerebours, Laura; Clement, Nathaniel J.; Vu, Mai-Anh T.; Sapiro, Guillermo; Heller, Nicole E.; Adcock, R. Alison

    2018-01-01

    Volitional exploration and learning are key to adaptive behavior, yet their characterization remains a complex problem for cognitive science. Exploration has been posited as a mechanism by which motivation promotes memory, but this relationship is not well-understood, in part because novel stimuli that motivate exploration also reliably elicit changes in neuromodulatory brain systems that directly alter memory formation, via effects on neural plasticity. To deconfound interrelationships between motivation, exploration, and memory formation we manipulated motivational state prior to entering a spatial context, measured exploratory responses to the context and novel stimuli within it, and then examined motivation and exploration as predictors of memory outcomes. To elicit spontaneous exploration, we used the physical space of an art exhibit with affectively rich content; we expected motivated exploration and memory to reflect multiple factors, including not only motivational valence, but also individual differences. Motivation was manipulated via an introductory statement framing exhibit themes in terms of Promotion- or Prevention-oriented goals. Participants explored the exhibit while being tracked by video. They returned 24 hours later for recall and spatial memory tests, followed by measures of motivation, personality, and relevant attitude variables. Promotion and Prevention condition participants did not differ in terms of group-level exploration time or memory metrics, suggesting similar motivation to explore under both framing contexts. However, exploratory behavior and memory outcomes were significantly more closely related under Promotion than Prevention, indicating that Prevention framing disrupted expected depth-of-encoding effects. Additionally, while trait measures predicted exploration similarly across framing conditions, traits interacted with motivational framing context and facial affect to predict memory outcomes. This novel characterization of motivated learning implies that dissociable behavioral and biological mechanisms, here varying as a function of valence, contribute to memory outcomes in complex, real-life environments. PMID:29558526

  3. Temporal trends and spatial patterns in nutrient export along the Mississippi River and its Tributaries

    NASA Astrophysics Data System (ADS)

    Stewart, B.; Li, L.

    2017-12-01

    The Mississippi River, the largest river in the U. S., exports excessive nutrients from the land to the sea, causing the problem of hypoxia in the Gulf of Mexico. In this research, we examined nutrient export along the Mississippi River and its tributaries to understand its trends and patterns and to identify the major factors contributing to these trends. We examined nutrient data from 1950 - 2017 for four sites along the Mississippi River and four tributary sites from the U. S. Geological Survey. The species included: total nitrogen, organic nitrogen, ammonia, nitrate, orthophosphate, and phosphorous. We analyzed the power law relationship of concentration and discharge, for which the export of nutrient species exhibited several trends. Both nitrogen (N) and phosphorous (P) species exhibited mostly chemodynamic behavior. This is in contrast to previous observations in smaller agricultural land where N and P export was mostly chemostatic with no significant change in concentration as discharge varies, suggesting possible scaling effects at different spatial scales. We also compared the average annual concentration over time at each site. The N concentration decreased from upstream to downstream, likely due to greater agricultural activities in the upstream Mississippi river and possible denitrification along the river. The N concentration also increased with time. The P species, however, fluctuated from site to site with no clear spatial patterns, but consistently exhibited higher concentrations at upstream sites with greater agricultural activities. The P species also fluctuated over time, likely due to patterns in discharge and agricultural activities. The results of this research can be further explored by calculating the total export of nutrients into the Gulf of Mexico to determine limits and drivers of nutrient export for better water management, thus helping prevent hypoxia and eutrophication within the Mississippi River basin.

  4. Increased natural reproduction and genetic diversity one generation after cessation of a steelhead trout (Oncorhynchus mykiss) conservation hatchery program.

    PubMed

    Berejikian, Barry A; Van Doornik, Donald M

    2018-01-01

    Spatial and temporal fluctuations in productivity and abundance confound assessments of captive propagation programs aimed at recovery of Threatened and Endangered populations. We conducted a 17 year before-after-control-impact experiment to determine the effects of a captive rearing program for anadromous steelhead trout (Oncorhynchus mykiss) on a key indicator of natural spawner abundance (naturally produced nests or 'redds'). The supplemented population exhibited a significant (2.6-fold) increase in redd abundance in the generation following supplementation. Four non-supplemented (control) populations monitored over the same 17 year period exhibited stable or decreasing trends in redd abundance. Expected heterozygosity in the supplemented population increased significantly. Allelic richness increased, but to a lesser (non-significant) degree. Estimates of the effective number of breeders increased from a harmonic mean of 24.4 in the generation before supplementation to 38.9 after supplementation. Several non-conventional aspects of the captive rearing program may have contributed to the positive response in the natural population.

  5. Spatial analysis of precipitation time series over the Upper Indus Basin

    NASA Astrophysics Data System (ADS)

    Latif, Yasir; Yaoming, Ma; Yaseen, Muhammad

    2018-01-01

    The upper Indus basin (UIB) holds one of the most substantial river systems in the world, contributing roughly half of the available surface water in Pakistan. This water provides necessary support for agriculture, domestic consumption, and hydropower generation; all critical for a stable economy in Pakistan. This study has identified trends, analyzed variability, and assessed changes in both annual and seasonal precipitation during four time series, identified herein as: (first) 1961-2013, (second) 1971-2013, (third) 1981-2013, and (fourth) 1991-2013, over the UIB. This study investigated spatial characteristics of the precipitation time series over 15 weather stations and provides strong evidence of annual precipitation by determining significant trends at 6 stations (Astore, Chilas, Dir, Drosh, Gupis, and Kakul) out of the 15 studied stations, revealing a significant negative trend during the fourth time series. Our study also showed significantly increased precipitation at Bunji, Chitral, and Skardu, whereas such trends at the rest of the stations appear insignificant. Moreover, our study found that seasonal precipitation decreased at some locations (at a high level of significance), as well as periods of scarce precipitation during all four seasons. The observed decreases in precipitation appear stronger and more significant in autumn; having 10 stations exhibiting decreasing precipitation during the fourth time series, with respect to time and space. Furthermore, the observed decreases in precipitation appear robust and more significant for regions at high elevation (>1300 m). This analysis concludes that decreasing precipitation dominated the UIB, both temporally and spatially including in the higher areas.

  6. Your brain on speed: cognitive performance of a spatial working memory task is not affected by walking speed

    PubMed Central

    Kline, Julia E.; Poggensee, Katherine; Ferris, Daniel P.

    2014-01-01

    When humans walk in everyday life, they typically perform a range of cognitive tasks while they are on the move. Past studies examining performance changes in dual cognitive-motor tasks during walking have produced a variety of results. These discrepancies may be related to the type of cognitive task chosen, differences in the walking speeds studied, or lack of controlling for walking speed. The goal of this study was to determine how young, healthy subjects performed a spatial working memory task over a range of walking speeds. We used high-density electroencephalography to determine if electrocortical activity mirrored changes in cognitive performance across speeds. Subjects stood (0.0 m/s) and walked (0.4, 0.8, 1.2, and 1.6 m/s) with and without performing a Brooks spatial working memory task. We hypothesized that performance of the spatial working memory task and the associated electrocortical activity would decrease significantly with walking speed. Across speeds, the spatial working memory task caused subjects to step more widely compared with walking without the task. This is typically a sign that humans are adapting their gait dynamics to increase gait stability. Several cortical areas exhibited power fluctuations time-locked to memory encoding during the cognitive task. In the somatosensory association cortex, alpha power increased prior to stimulus presentation and decreased during memory encoding. There were small significant reductions in theta power in the right superior parietal lobule and the posterior cingulate cortex around memory encoding. However, the subjects did not show a significant change in cognitive task performance or electrocortical activity with walking speed. These findings indicate that in young, healthy subjects walking speed does not affect performance of a spatial working memory task. These subjects can devote adequate cortical resources to spatial cognition when needed, regardless of walking speed. PMID:24847239

  7. Tree species exhibit complex patterns of distribution in bottomland hardwood forests

    Treesearch

    Luben D Dimov; Jim L Chambers; Brian R. Lockhart

    2013-01-01

    & Context Understanding tree interactions requires an insight into their spatial distribution. & Aims We looked for presence and extent of tree intraspecific spatial point pattern (random, aggregated, or overdispersed) and interspecific spatial point pattern (independent, aggregated, or segregated). & Methods We established twelve 0.64-ha plots in natural...

  8. Chimpanzees and Bonobos Exhibit Divergent Spatial Memory Development

    ERIC Educational Resources Information Center

    Rosati, Alexandra G.; Hare, Brian

    2012-01-01

    Spatial cognition and memory are critical cognitive skills underlying foraging behaviors for all primates. While the emergence of these skills has been the focus of much research on human children, little is known about ontogenetic patterns shaping spatial cognition in other species. Comparative developmental studies of nonhuman apes can…

  9. Constructing Spatial Meaning: Spatial Affordances in Museum Design

    ERIC Educational Resources Information Center

    Wineman, Jean D.; Peponis, John

    2010-01-01

    Informal education in museums is structured through movement in space. This article summarizes a range of research that examines the role of spatial layout in shaping the ways in which visitors explore, engage, and understand museums and museum exhibitions. It is demonstrated that behavior patterns are systematically linked to spatial…

  10. Microphytobenthos potential productivity estimated in three tidal embayments of the San Francisco Bay system

    USGS Publications Warehouse

    Guarini, Jean-Marc; Cloern, James E.; Edmunds, Jody L.; Gros, Philippe

    2002-01-01

    In this paper we describe a three-step procedure to infer the spatial heterogeneity in microphytobenthos primary productivity at the scale of tidal estuaries and embayments. The first step involves local measurement of the carbon assimilation rate of benthic microalgae to determine the parameters of the photosynthesis-irradiance (P-E) curves (using non-linear optimization methods). In the next step, a resampling technique is used to rebuild pseudo-sampling distributions of the local productivity estimates; these provide error estimates for determining the significance level of differences between sites. The third step combines the previous results with deterministic models of tidal elevation and solar irradiance to compute mean and variance of the daily areal primary productivity over an entire intertidal mudflat area within each embayment. This scheme was applied on three different intertidal mudflat regions of the San Francisco Bay estuary during autumn 1998. Microphytobenthos productivity exhibits strong (ca. 3-fold) significant differences among the major sub-basins of San Francisco Bay. This spatial heterogeneity is attributed to two main causes: significant differences in the photosynthetic competence (P-E parameters) of the microphytobenthos in the different sub-basins, and spatial differences in the phase shifts between the tidal and solar cycles controlling the exposure of intertidal areas to sunlight. The procedure is general and can be used in other estuaries to assess the magnitude and patterns of spatial variability of microphytobenthos productivity at the level of the ecosystems.

  11. Microphytobenthic potential productivity estimated in three tidal embayments of the San Francisco Bay: A comparative study

    USGS Publications Warehouse

    Guarini, J.-M.; Cloern, James E.; Edmunds, J.

    2002-01-01

    In this paper we describe a three-step procedure to infer the spatial heterogeneity in microphytobenthos primary productivity at the scale of tidal estuaries and embayments. The first step involves local measurement of the carbon assimilation rate of benthic microalgae to determine the parameters of the photosynthesis-irradiance (P-E) curves (using non-linear optimization methods). In the next step, a resampling technique is used to rebuild pseudo-sampling distributions of the local productivity estimates; these provide error estimates for determining the significance level of differences between sites. The third step combines the previous results with deterministic models of tidal elevation and solar irradiance to compute mean and variance of the daily areal primary productivity over an entire intertidal mudflat area within each embayment. This scheme was applied on three different intertidal mudflat regions of the San Francisco Bay estuary during autumn 1998. Microphytobenthos productivity exhibits strong (ca. 3-fold) significant differences among the major sub-basins of San Francisco Bay. This spatial heterogeneity is attributed to two main causes: significant differences in the photosynthetic competence (P-E parameters) of the microphytobenthos in the different sub-basins, and spatial differences in the phase shifts between the tidal and solar cycles controlling the exposure of intertidal areas to sunlight. The procedure is general and can be used in other estuaries to assess the magnitude and patterns of spatial variability of microphytobenthos productivity at the level of the ecosystems.

  12. The Importance of Large-Diameter Trees to Forest Structural Heterogeneity

    PubMed Central

    Lutz, James A.; Larson, Andrew J.; Freund, James A.; Swanson, Mark E.; Bible, Kenneth J.

    2013-01-01

    Large-diameter trees dominate the structure, dynamics and function of many temperate and tropical forests. However, their attendant contributions to forest heterogeneity are rarely addressed. We established the Wind River Forest Dynamics Plot, a 25.6 ha permanent plot within which we tagged and mapped all 30,973 woody stems ≥1 cm dbh, all 1,966 snags ≥10 cm dbh, and all shrub patches ≥2 m2. Basal area of the 26 woody species was 62.18 m2/ha, of which 61.60 m2/ha was trees and 0.58 m2/ha was tall shrubs. Large-diameter trees (≥100 cm dbh) comprised 1.5% of stems, 31.8% of basal area, and 17.6% of the heterogeneity of basal area, with basal area dominated by Tsuga heterophylla and Pseudotsuga menziesii. Small-diameter subpopulations of Pseudotsuga menziesii, Tsuga heterophylla and Thuja plicata, as well as all tree species combined, exhibited significant aggregation relative to the null model of complete spatial randomness (CSR) up to 9 m (P≤0.001). Patterns of large-diameter trees were either not different from CSR (Tsuga heterophylla), or exhibited slight aggregation (Pseudotsuga menziesii and Thuja plicata). Significant spatial repulsion between large-diameter and small-diameter Tsuga heterophylla suggests that large-diameter Tsuga heterophylla function as organizers of tree demography over decadal timescales through competitive interactions. Comparison among two forest dynamics plots suggests that forest structural diversity responds to intermediate-scale environmental heterogeneity and disturbances, similar to hypotheses about patterns of species richness, and richness- ecosystem function. Large mapped plots with detailed within-plot environmental spatial covariates will be required to test these hypotheses. PMID:24376579

  13. The importance of large-diameter trees to forest structural heterogeneity.

    PubMed

    Lutz, James A; Larson, Andrew J; Freund, James A; Swanson, Mark E; Bible, Kenneth J

    2013-01-01

    Large-diameter trees dominate the structure, dynamics and function of many temperate and tropical forests. However, their attendant contributions to forest heterogeneity are rarely addressed. We established the Wind River Forest Dynamics Plot, a 25.6 ha permanent plot within which we tagged and mapped all 30,973 woody stems ≥ 1 cm dbh, all 1,966 snags ≥ 10 cm dbh, and all shrub patches ≥ 2 m(2). Basal area of the 26 woody species was 62.18 m(2)/ha, of which 61.60 m(2)/ha was trees and 0.58 m(2)/ha was tall shrubs. Large-diameter trees (≥ 100 cm dbh) comprised 1.5% of stems, 31.8% of basal area, and 17.6% of the heterogeneity of basal area, with basal area dominated by Tsuga heterophylla and Pseudotsuga menziesii. Small-diameter subpopulations of Pseudotsuga menziesii, Tsuga heterophylla and Thuja plicata, as well as all tree species combined, exhibited significant aggregation relative to the null model of complete spatial randomness (CSR) up to 9 m (P ≤ 0.001). Patterns of large-diameter trees were either not different from CSR (Tsuga heterophylla), or exhibited slight aggregation (Pseudotsuga menziesii and Thuja plicata). Significant spatial repulsion between large-diameter and small-diameter Tsuga heterophylla suggests that large-diameter Tsuga heterophylla function as organizers of tree demography over decadal timescales through competitive interactions. Comparison among two forest dynamics plots suggests that forest structural diversity responds to intermediate-scale environmental heterogeneity and disturbances, similar to hypotheses about patterns of species richness, and richness- ecosystem function. Large mapped plots with detailed within-plot environmental spatial covariates will be required to test these hypotheses.

  14. The effects of heavy particle irradiation on exploration and response to environmental change

    NASA Astrophysics Data System (ADS)

    Casadesus, G.; Shukitt-Hale, B.; Cantuti-Castelvetri, I.; Rabin, B.; Joseph, J.

    Free radicals produced by exposure to heavy particles have been found to produce motor and behavioral toxicity effects in rats similar to those found during aging. The present research was designed to investigate the effects of exposure to 56Fe particles on the ability to detect novel arrangements in a given environment of male Sprague-Dawley rats. Using a test of spatial memory previously demonstrated to be sensitive to aging, open-field activity and reaction to spatial and non-spatial changes were measured in a group that received a dose of 1.5 Gy (n=10) of 56Fe heavy particle radiation or in non- radiated controls. Animals irradiated with 1.5 Gy of56Fe particles exhibited some age-like effects in animals tested, even though they were for the most part, subtle. Animals took longer to enter, visited less and spent significantly less time in the middle and the center portions of the open-field independently of total frequency and duration of activity of both groups. Likewise, irradiated subjects reacted significantly more to novel objects placed in the open-field than did controls. However, irradiated subjects did not vary from controls in their exploration patterns when objects in the open-field were spatially rearranged. Thus, irradiation with a dose of 1.5 Gy of 56Fe high-energy particle radiation elicited age-like effects in general open-field exploratory behavior, but did not elicit age- like effects during the spatial and non-spatial rearrangement tasks. Supported by N.A.S.A. Grant NAG9-1190.

  15. The effects of heavy particle irradiation on exploration and response to environmental change

    NASA Astrophysics Data System (ADS)

    Casadesus, G.; Shukitt-Hale, B.; Cantuti-Castelvetri, I.; Rabin, B. M.; Joseph, J. A.

    2004-01-01

    Free radicals produced by exposure to heavy particles have been found to produce motor and cognitive behavioral toxicity effects in rats similar to those found during aging. The present research was designed to investigate the effects of exposure to 56Fe particles on the ability of male Sprague-Dawley rats to detect novel arrangements in a given environment. Using a test of spatial memory previously demonstrated to be sensitive to aging, open field activity and reaction to spatial and non-spatial changes were measured in a group that received a dose of 1.5 Gy ( n=10) of 56Fe heavy particle radiation or in non-radiated controls ( n=10). Animals irradiated with 1.5 Gy of 56Fe particles exhibited some age-like effects in rats tested, even though they were, for the most part, subtle. Animals took longer to enter, visited less and spent significantly less time in the middle and the center portions of the open field, independently of total frequency and duration of activity of both groups. Likewise, irradiated subjects spend significantly more time exploring novel objects placed in the open field than did controls. However, irradiated subjects did not vary from controls in their exploration patterns when objects in the open field were spatially rearranged. Thus, irradiation with a dose of 1.5 Gy of 56Fe high-energy particle radiation elicited age-like effects in general open field exploratory behavior, but did not elicit age-like effects during the spatial and non-spatial rearrangement tasks.

  16. The effects of heavy particle irradiation on exploration and response to environmental change

    NASA Technical Reports Server (NTRS)

    Casadesus, G.; Shukitt-Hale, B.; Cantuti-Castelvetri, I.; Rabin, B. M.; Joseph, J. A.

    2004-01-01

    Free radicals produced by exposure to heavy particles have been found to produce motor and cognitive behavioral toxicity effects in rats similar to those found during aging. The present research was designed to investigate the effects of exposure to 56Fe particles on the ability of male Sprague-Dawley rats to detect novel arrangements in a given environment. Using a test of spatial memory previously demonstrated to be sensitive to aging, open field activity and reaction to spatial and non-spatial changes were measured in a group that received a dose of 1.5 Gy (n=10) of 56Fe heavy particle radiation or in non-radiated controls (n=10). Animals irradiated with 1.5 Gy of 56Fe particles exhibited some age-like effects in rats tested, even though they were, for the most part, subtle. Animals took longer to enter, visited less and spent significantly less time in the middle and the center portions of the open field, independently of total frequency and duration of activity of both groups. Likewise, irradiated subjects spend significantly more time exploring novel objects placed in the open field than did controls. However, irradiated subjects did not vary from controls in their exploration patterns when objects in the open field were spatially rearranged. Thus, irradiation with a dose of 1.5 Gy of 56Fe high-energy particle radiation elicited age-like effects in general open field exploratory behavior, but did not elicit age-like effects during the spatial and non-spatial rearrangement tasks. Published by Elsevier Ltd on behalf of COSPAR.

  17. Spatial height directed microfluidic synthesis of transparent inorganic upconversion nano film

    NASA Astrophysics Data System (ADS)

    Liu, Xiaoxia; Zhu, Cheng; Liao, Wei; Jin, Junyang; Ni, Yaru; Lu, Chunhua; Xu, Zhongzi

    2017-11-01

    A microfluidic-based synthesis of an inorganic upconversion nano film has been developed with a large area of dense-distributed NaYF4 crystal grains in a silica glass micro-reactor and the film exhibits high transparence, strong upconversion luminescence and robust adhesion with the substrate. The spatial heights of micro-reactors are tuned between 31 and 227 mm, which can regulate flow regimes. The synergistic effect of spatial height and fluid regime is put forward, which influences diffusion paths and assembly ways of different precursor molecules and consequently directs final distributions and morphologies of crystal grains, as well as optical properties due to diversity of surface and thickness of films. The spatial height of 110 mm is advantageous for high transmittance of upconversion film due to the flat surface and appropriate film thickness of 67 nm. The height of 150 mm is in favor of uniform distribution of upconversion fluorescence and achieving the strongest fluorescence due to minimized optical loss. Such a transparent upconversion film with a large area of uniform distribution is promising to promote the application of upconversion materials and spatial height directed microfluidic regime have a certain significance on many microfluidic synthesis.

  18. Spatial coherence resonance and spatial pattern transition induced by the decrease of inhibitory effect in a neuronal network

    NASA Astrophysics Data System (ADS)

    Tao, Ye; Gu, Huaguang; Ding, Xueli

    2017-10-01

    Spiral waves were observed in the biological experiment on rat brain cortex with the application of carbachol and bicuculline which can block inhibitory coupling from interneurons to pyramidal neurons. To simulate the experimental spiral waves, a two-dimensional neuronal network composed of pyramidal neurons and inhibitory interneurons was built. By decreasing the percentage of active inhibitory interneurons, the random-like spatial patterns change to spiral waves and to random-like spatial patterns or nearly synchronous behaviors. The spiral waves appear at a low percentage of inhibitory interneurons, which matches the experimental condition that inhibitory couplings of the interneurons were blocked. The spiral waves exhibit a higher order or signal-to-noise ratio (SNR) characterized by spatial structure function than both random-like spatial patterns and nearly synchronous behaviors, which shows that changes of the percentage of active inhibitory interneurons can induce spatial coherence resonance-like behaviors. In addition, the relationship between the coherence degree and the spatial structures of the spiral waves is identified. The results not only present a possible and reasonable interpretation to the spiral waves observed in the biological experiment on the brain cortex with disinhibition, but also reveal that the spiral waves exhibit more ordered degree in spatial patterns.

  19. [Spatial heterogeneity and influencing factors of soil phosphorus concentration in a mid-subtropical Choerospondias axillaris deciduous broad-leaved forest, China.

    PubMed

    Hu, Rui Bin; Fang, Xi; Xiang, Wen Hua; Jiang, Fang; Lei, Pi Feng; Zhao, Li Juan; Zhu, Wen Juan; Deng, Xiang Wen

    2016-03-01

    In order to investigate spatial variations in soil phosphorus (P) concentration and the influencing factors, one permanent plot of 1 hm 2 was established and stand structure was surveyed in Choerospondias axillaries deciduous broadleaved forest in Dashanchong Forest Park in Changsha County, Hunan Province, China. Soil samples were collected with equidistant grid point sampling method and soil P concentration and its spatial variation were analyzed by using geo-statistics and geographical information system (GIS) techniques. The results showed that the variations of total P and available P concentrations in humus layer and in the soil profile at depth of 0-10, 10-20 and 20-30 cm were moderate and the available P showed higher variability in a specific soil layer compared with total P. Concentrations of total P and available P in soil decreased, while the variations increased with the increase in soil depth. The total P and available P showed high spatial autocorrelation, primarily resulted from the structural factors. The spatial heterogeneity of available P was stronger than that of total P, and the spatial autocorrelation ranges of total P and available P varied from 92.80 to 168.90 m and from 79.43 to 106.20 m in different soil layers, respectively. At the same soil depth, fractal dimensions of total P were higher than that of available P, with more complex spatial pattern, while available P showed stronger spatial correlation with stronger spatial structure. In humus layer and soil depths of 0-10, 10-20 and 20-30 cm, the spatial variation pattern of total P and available P concentrations showed an apparent belt-shaped and spot massive gradient change. The high value appeared at low elevation and valley position, and the low value appeared in the high elevation and ridge area. The total P and available P concentrations showed significantly negative correlation with elevation and litter, but the relationship with convexity, species, numbers and soil pH was not significant. The total P and available P exhibited significant positive correlations with soil organic carbon (SOC), total nitrogen concentration, indicating the leaching characteristics of soil P. Its spatial variability was affected by many interactive factors.

  20. Spatial analysis of lymphatic filariasis distribution in the Nile Delta in relation to some environmental variables using geographic information system technology.

    PubMed

    Hassan, A N; Dister, S; Beck, L

    1998-04-01

    Geographic information system (GIS) was used to analyze the spatial distribution of filariasis in the Nile Delta. The study involved 201 villages belonging to Giza, Qalubiya, Monoufiya, Gharbiya, and Dakahliya governorates. Villages with similar microfilarial (mf) prevalence rates were observed to cluster within 1-2 km distance, then, clustering started to decrease significantly with distance up to 5 km (Pearson correlation coefficient = -0.98). the likelihood of negative and high prevalence villages being contiguous was very low (approximately 1.8%, n = 612 village-pairs) indicating homogeneity in disease processes within the defined spatial scales. Of the villages located within 2 km from the main Nile branches (n = 46), 95% exhibited low prevalence. In addition, the spatial pattern of mf prevalence was shown to be negatively associated with annual rainfall and relative humidity, while it was positively associated with annual daily temperature. Average mf prevalence in warmer, relatively drier areas receiving 25 mm of rain was significantly higher (3.9%) than that in less warmer but more humid areas receiving 50 mm of rain (1.6%) (P < 0.0001). Based on the results of the present study, GIS was used to generate a "filariasis risk map" that could be used by health authorities to efficiently direct surveillance and control efforts. This investigation identified some of the factors underlying filariasis spatial pattern, quantified clustering and demonstrated the potential of GIS application in vector-borne disease epidemiology.

  1. Experimentally Isolating the Contributions of a Disturbed Ephemeral Drainage to a Headwater Stream in the Southern Appalachians

    NASA Astrophysics Data System (ADS)

    Gannon, J. P.; Lord, M.; Kinner, D. A.

    2015-12-01

    A growing body of evidence suggests contributions to runoff from ephemeral channels during events can exhibit significant control over water quality in higher order streams. Furthermore, field observations from a steep Appalachian catchment influenced by human activity suggest these disturbed ephemeral drainages exhibit significant control over turbidity, water temperature, and conductivity levels downstream. High turbidity during stormflow is a water quality problem in many areas of the Southern Appalachians. However, upland ephemeral channels are not included in the jurisdiction of the Clean Water Act. This offers little recourse if their contributions degrade the water quality of larger-scale streams and highlights the need for robust evidence of the potential impacts of ephemeral drainages. The aim of this research is to isolate the contribution of a disturbed ephemeral drainage by diverting its flow from the study stream network. Spatially and temporally distributed stream water samples taken during storms, when the channel is diverted or allowed to flow normally, will allow us to assess its contribution. In this poster, we present initial spatial and temporal streamwater chemistry and turbidity data as well as a detailed description of the stream network, study design, and diversion construction. We anticipate the findings of this study will be relevant to describing the environmental impact of disturbed ephemeral channels and to describing their potential influence on other water chemistry parameters downstream.

  2. Effects of immunotoxic and electrolytic lesions of medial septal area on spatial short-term memory in rats.

    PubMed

    Dashiani, M G; Kruashvili, L B; Rusadze, Kh Z; Matatradze, S B; Beselia, G V

    2015-02-01

    In the present study electrolytic and the immunotoxins (192 IgG saporin and GAT1-SAP) lesions of medial septal area (MS) were used to investigate the importance of cholinergic and GABAergic MS neurons in spatial working memory using spatial alternation task. In our experiments electrolytic lesions destroyed on average 69% of the intact MS. Examination of the AChE stained sections showed that after injections of 192 IgG saporin into the MS, animals exhibited significantly less AChE staining in MS as compared to sections obtained from control animals. Intraseptal GAT1-SAP preferentially reduced GABAergic neurons as compared to cholinergic neurons in the MS. The results of present study indicate that spatial short-term memory is affected only by electrolytic but not 192 IgG saporin or GAT1-SAP lesions. The behavioral testing showed that 192 IgG saporin treated rats, relative to control rats, had a significantly lower level in the number of arms entered during the testing session. However, the groups did not differ in the level of alternation behavior. GAT1-SAP lesioned rats showed that the percent alternation scores and the number of arms that the rat entered in the maze were not significantly different from control rats. These findings indicate that deficits observed after septal electrolytic lesions cannot be accounted solely to the loss of cholinergic or GABAergic septohippocampal projections. To determine more definitively whether septohippocampal projection neurons are required for the spatial short-term memory it would be ideal to produce in future combined lesions of the cholinergic and GABA-ergic septohippocampal projection neurons using 192 IgG-saporin and GAT1-SAP.

  3. Spatial Fluctuations of the Intergalactic Temperature-Density Relation After Hydrogen Reionization

    NASA Astrophysics Data System (ADS)

    Keating, Laura C.; Puchwein, Ewald; Haehnelt, Martin G.

    2018-04-01

    The thermal state of the post-reionization IGM is sensitive to the timing of reionization and the nature of the ionizing sources. We have modelled here the thermal state of the IGM in cosmological radiative transfer simulations of a realistic, extended, spatially inhomogeneous hydrogen reionization process, carefully calibrated with Lyα forest data. We compare these with cosmological simulations run using a spatially homogeneous ionizing background. The simulations with a realistic growth of ionized regions and a realistic spread in reionization redshifts show, as expected, significant spatial fluctuations in the temperature-density relation (TDR) of the post-reionization IGM. The most recently ionized regions are hottest and exhibit a flatter TDR. In simulations consistent with the average TDR inferred from Lyα forest data, these spatial fluctuations have a moderate but noticeable effect on the statistical properties of the Lyα opacity of the IGM at z ˜ 4 - 6. This should be taken into account in accurate measurements of the thermal properties of the IGM and the free-streaming of dark matter from Lyα forest data in this redshift range. The spatial variations of the TDR predicted by our simulations are, however, smaller by about a factor two than would be necessary to explain the observed large spatial opacity fluctuations on large (≥ 50 h-1 comoving Mpc) scales at z ≳ 5.5.

  4. Spatial fluctuations of the intergalactic temperature-density relation after hydrogen reionization

    NASA Astrophysics Data System (ADS)

    Keating, Laura C.; Puchwein, Ewald; Haehnelt, Martin G.

    2018-07-01

    The thermal state of the post-reionization IGM is sensitive to the timing of reionization and the nature of the ionizing sources. We have modelled here the thermal state of the IGM in cosmological radiative transfer simulations of a realistic, extended, spatially inhomogeneous hydrogen reionization process, carefully calibrated with Ly α forest data. We compare these with cosmological simulations run using a spatially homogeneous ionizing background. The simulations with a realistic growth of ionized regions and a realistic spread in reionization redshifts show, as expected, significant spatial fluctuations in the temperature-density relation (TDR) of the post-reionization IGM. The most recently ionized regions are hottest and exhibit a flatter TDR. In simulations consistent with the average TDR inferred from Ly α forest data, these spatial fluctuations have a moderate but noticeable effect on the statistical properties of the Ly α opacity of the IGM at z ˜ 4-6. This should be taken into account in accurate measurements of the thermal properties of the IGM and the free-streaming of dark matter from Ly α forest data in this redshift range. The spatial variations of the TDR predicted by our simulations are, however, smaller by about a factor of 2 than would be necessary to explain the observed large spatial opacity fluctuations on large (≥50 h-1 comoving Mpc) scales atz ≳ 5.5.

  5. Finding a Place To Stand: Negotiating the Spatial Configuration of the Networked Computer Classroom.

    ERIC Educational Resources Information Center

    Kent-Drury, Roxanne

    1998-01-01

    Theorizes the spatial dynamics of both traditional and Internet-networked classrooms to reveal that both exhibit indeterminate spatial characteristics, but that network connectivity renders this indeterminacy visible. Argues that networked classrooms need not be disorienting, if students recreate a center by designing a class Web site, creating…

  6. Effect of long-term mechanical perturbation on intertidal soft-bottom meiofaunal community spatial structure

    NASA Astrophysics Data System (ADS)

    Boldina, Inna; Beninger, Peter G.; Le Coz, Maïwen

    2014-01-01

    Situated at the interface of the microbial and macrofaunal compartments, soft-bottom meiofauna accomplish important ecological functions. However, little is known of their spatial distribution in the benthic environment. To assess the effects of long-term mechanical disturbance on soft-bottom meiofaunal spatial distribution, we compared a site subjected to long-term clam digging to a nearby site untouched by such activities, in Bourgneuf Bay, on the Atlantic coast of France. Six patterned replicate samples were taken at 3, 6, 9, 12, 15, 18, 21 and 24 cm lags, all sampling stations being separated by 5 m. A combined correlogram-variogram approach was used to enhance interpretation of the meiofaunal spatial distribution; in particular, the definition of autocorrelation strength and its statistical significance, as well as the detailed characteristics of the periodic spatial structure of nematode assemblages, and the determination of the maximum distance of their spatial autocorrelation. At both sites, nematodes and copepods clearly exhibited aggregated spatial structure at the meso scale; this structure was attenuated at the impacted site. The nematode spatial distribution showed periodicity at the non-impacted site, but not at the impacted site. This is the first explicit report of a periodic process in meiofaunal spatial distribution. No such cyclic spatial process was observed for the more motile copepods at either site. This first study to indicate the impacts of long-term anthropogenic mechanical perturbation on meiofaunal spatial structure opens the door to a new dimension of mudflat ecology. Since macrofaunal predator search behaviour is known to be strongly influenced by prey spatial structure, the alteration of this structure may have important consequences for ecosystem functioning.

  7. Chronic spatial working memory deficit associated with the superior longitudinal fasciculus: a study using voxel-based lesion-symptom mapping and intraoperative direct stimulation in right prefrontal glioma surgery.

    PubMed

    Kinoshita, Masashi; Nakajima, Riho; Shinohara, Harumichi; Miyashita, Katsuyoshi; Tanaka, Shingo; Okita, Hirokazu; Nakada, Mitsutoshi; Hayashi, Yutaka

    2016-10-01

    OBJECTIVE Although the right prefrontal region is regarded as a silent area, chronic deficits of the executive function, including working memory (WM), could occur after resection of a right prefrontal glioma. This may be overlooked by postoperative standard examinations, and the disabilities could affect the patient's professional life. The right prefrontal region is a part of the frontoparietal network and is subserved by the superior longitudinal fasciculus (SLF); however, the role of the SLF in spatial WM is unclear. This study investigated a persistent spatial WM deficit in patients who underwent right prefrontal glioma resection, and evaluated the relationship between the spatial WM deficit and the SLF. METHODS Spatial WM was examined in 24 patients who underwent prefrontal glioma resection (right, n = 14; left, n = 10) and in 14 healthy volunteers using a spatial 2-back task during the long-term postoperative period. The neural correlates of spatial WM were evaluated using lesion mapping and voxel-based lesion-symptom mapping. In addition, the spatial 2-back task was performed during surgery under direct subcortical electrical stimulation in 2 patients with right prefrontal gliomas. RESULTS Patients with a right prefrontal lesion had a significant chronic spatial WM deficit. Voxel-based lesion-symptom mapping analysis revealed a significant correlation between spatial WM deficit and the region that overlapped the first and second segments of the SLF (SLF I and SLF II). Two patients underwent awake surgery and had difficulties providing the correct responses in the spatial 2-back task with direct subcortical electrical stimulation on the SLF I, which was preserved and confirmed by postoperative diffusion tensor imaging tractography. These patients exhibited no spatial WM deficits during the postoperative immediate and long-term periods. CONCLUSIONS Spatial WM deficits may persist in patients who undergo resection of the tumor located in the right prefrontal brain parenchyma. Injury to the dorsal frontoparietal subcortical white matter pathway, i.e., the SLF I or SLF I and II, could play a causal role in this chronic deficit. A persistent spatial WM deficit, without motor and language deficits, could affect the professional life of the patient. In such cases, awake surgery would be useful to detect the spatial WM network with appropriate task during tumor exploration.

  8. Analyzing spatial clustering and the spatiotemporal nature and trends of HIV/AIDS prevalence using GIS: the case of Malawi, 1994-2010.

    PubMed

    Zulu, Leo C; Kalipeni, Ezekiel; Johannes, Eliza

    2014-05-23

    Although local spatiotemporal analysis can improve understanding of geographic variation of the HIV epidemic, its drivers, and the search for targeted interventions, it is limited in sub-Saharan Africa. Despite recent declines, Malawi's estimated 10.0% HIV prevalence (2011) remained among the highest globally. Using data on pregnant women in Malawi, this study 1) examines spatiotemporal trends in HIV prevalence 1994-2010, and 2) for 2010, identifies and maps the spatial variation/clustering of factors associated with HIV prevalence at district level. Inverse distance weighting was used within ArcGIS Geographic Information Systems (GIS) software to generate continuous surfaces of HIV prevalence from point data (1994, 1996, 1999, 2001, 2003, 2005, 2007, and 2010) obtained from surveillance antenatal clinics. From the surfaces prevalence estimates were extracted at district level and the results mapped nationally. Spatial dependency (autocorrelation) and clustering of HIV prevalence were also analyzed. Correlation and multiple regression analyses were used to identify factors associated with HIV prevalence for 2010 and their spatial variation/clustering mapped and compared to HIV clustering. Analysis revealed wide spatial variation in HIV prevalence at regional, urban/rural, district and sub-district levels. However, prevalence was spatially leveling out within and across 'sub-epidemics' while declining significantly after 1999. Prevalence exhibited statistically significant spatial dependence nationally following initial (1995-1999) localized, patchy low/high patterns as the epidemic spread rapidly. Locally, HIV "hotspots" clustered among eleven southern districts/cities while a "coldspot" captured configurations of six central region districts. Preliminary multiple regression of 2010 HIV prevalence produced a model with four significant explanatory factors (adjusted R2 = 0.688): mean distance to main roads, mean travel time to nearest transport, percentage that had taken an HIV test ever, and percentage attaining a senior primary education. Spatial clustering linked some factors to particular subsets of high HIV-prevalence districts. Spatial analysis enhanced understanding of local spatiotemporal variation in HIV prevalence, possible underlying factors, and potential for differentiated spatial targeting of interventions. Findings suggest that intervention strategies should also emphasize improved access to health/HIV services, basic education, and syphilis management, particularly in rural hotspot districts, as further research is done on drivers at finer scale.

  9. Analyzing spatial clustering and the spatiotemporal nature and trends of HIV/AIDS prevalence using GIS: the case of Malawi, 1994-2010

    PubMed Central

    2014-01-01

    Background Although local spatiotemporal analysis can improve understanding of geographic variation of the HIV epidemic, its drivers, and the search for targeted interventions, it is limited in sub-Saharan Africa. Despite recent declines, Malawi’s estimated 10.0% HIV prevalence (2011) remained among the highest globally. Using data on pregnant women in Malawi, this study 1) examines spatiotemporal trends in HIV prevalence 1994-2010, and 2) for 2010, identifies and maps the spatial variation/clustering of factors associated with HIV prevalence at district level. Methods Inverse distance weighting was used within ArcGIS Geographic Information Systems (GIS) software to generate continuous surfaces of HIV prevalence from point data (1994, 1996, 1999, 2001, 2003, 2005, 2007, and 2010) obtained from surveillance antenatal clinics. From the surfaces prevalence estimates were extracted at district level and the results mapped nationally. Spatial dependency (autocorrelation) and clustering of HIV prevalence were also analyzed. Correlation and multiple regression analyses were used to identify factors associated with HIV prevalence for 2010 and their spatial variation/clustering mapped and compared to HIV clustering. Results Analysis revealed wide spatial variation in HIV prevalence at regional, urban/rural, district and sub-district levels. However, prevalence was spatially leveling out within and across ‘sub-epidemics’ while declining significantly after 1999. Prevalence exhibited statistically significant spatial dependence nationally following initial (1995-1999) localized, patchy low/high patterns as the epidemic spread rapidly. Locally, HIV “hotspots” clustered among eleven southern districts/cities while a “coldspot” captured configurations of six central region districts. Preliminary multiple regression of 2010 HIV prevalence produced a model with four significant explanatory factors (adjusted R2 = 0.688): mean distance to main roads, mean travel time to nearest transport, percentage that had taken an HIV test ever, and percentage attaining a senior primary education. Spatial clustering linked some factors to particular subsets of high HIV-prevalence districts. Conclusions Spatial analysis enhanced understanding of local spatiotemporal variation in HIV prevalence, possible underlying factors, and potential for differentiated spatial targeting of interventions. Findings suggest that intervention strategies should also emphasize improved access to health/HIV services, basic education, and syphilis management, particularly in rural hotspot districts, as further research is done on drivers at finer scale. PMID:24886573

  10. Detection and description of non-linear interdependence in normal multichannel human EEG data.

    PubMed

    Breakspear, M; Terry, J R

    2002-05-01

    This study examines human scalp electroencephalographic (EEG) data for evidence of non-linear interdependence between posterior channels. The spectral and phase properties of those epochs of EEG exhibiting non-linear interdependence are studied. Scalp EEG data was collected from 40 healthy subjects. A technique for the detection of non-linear interdependence was applied to 2.048 s segments of posterior bipolar electrode data. Amplitude-adjusted phase-randomized surrogate data was used to statistically determine which EEG epochs exhibited non-linear interdependence. Statistically significant evidence of non-linear interactions were evident in 2.9% (eyes open) to 4.8% (eyes closed) of the epochs. In the eyes-open recordings, these epochs exhibited a peak in the spectral and cross-spectral density functions at about 10 Hz. Two types of EEG epochs are evident in the eyes-closed recordings; one type exhibits a peak in the spectral density and cross-spectrum at 8 Hz. The other type has increased spectral and cross-spectral power across faster frequencies. Epochs identified as exhibiting non-linear interdependence display a tendency towards phase interdependencies across and between a broad range of frequencies. Non-linear interdependence is detectable in a small number of multichannel EEG epochs, and makes a contribution to the alpha rhythm. Non-linear interdependence produces spatially distributed activity that exhibits phase synchronization between oscillations present at different frequencies. The possible physiological significance of these findings are discussed with reference to the dynamical properties of neural systems and the role of synchronous activity in the neocortex.

  11. Effects of population succession on demographic and genetic processes: predictions and tests in the daylily Hemerocallis thunbergii (Liliaceae).

    PubMed

    Chung, Mi Yoon; Nason, John D; Chung, Myong Gi

    2007-07-01

    Spatial genetic structure within plant populations is influenced by variation in demographic processes through space and time, including a population's successional status. To determine how demographic structure and fine-scale genetic structure (FSGS) change with stages in a population's successional history, we studied Hemerocallis thunbergii (Liliaceae), a nocturnal flowering and hawkmoth-pollinated herbaceous perennial with rapid population turnover dynamics. We examined nine populations assigned to three successive stages of population succession: expansion, maturation, and senescence. We developed stage-specific expectations for within-population demographic and genetic structure, and then for each population quantified the spatial aggregation of individuals and genotypes using spatial autocorrelation methods (nonaccumulative O-ring and kinship statistics, respectively), and at the landscape level measured inbreeding and genetic structure using Wright's F-statistics. Analyses using the O-ring statistic revealed significant aggregation of individuals at short spatial scales in expanding and senescing populations, in particular, which may reflect restricted seed dispersal around maternal individuals combined with relatively low local population densities at these stages. Significant FSGS was found for three of four expanding, no mature, and only one senescing population, a pattern generally consistent with expectations of successional processes. Although allozyme genetic diversity was high within populations (mean %P = 78.9 and H(E) = 0.281), landscape-level differentiation among sites was also high (F(ST) = 0.166) and all populations exhibited a significant deficit of heterozygotes relative to Hardy-Weinberg expectations (range F = 0.201-0.424, mean F(IS) = 0.321). Within populations, F was not correlated with the degree of FSGS, thus suggesting inbreeding due primarily to selfing as opposed to mating among close relatives in spatially structured populations. Our results demonstrate considerable variation in the spatial distribution of individuals and patterns and magnitude of FSGS in H. thunbergii populations across the landscape. This variation is generally consistent with succession-stage-specific differences in ecological processes operating within these populations.

  12. Spatial encoding in spinal sensorimotor circuits differs in different wild type mice strains

    PubMed Central

    Thelin, Jonas; Schouenborg, Jens

    2008-01-01

    Background Previous studies in the rat have shown that the spatial organisation of the receptive fields of nociceptive withdrawal reflex (NWR) system are functionally adapted through experience dependent mechanisms, termed somatosensory imprinting, during postnatal development. Here we wanted to clarify 1) if mice exhibit a similar spatial encoding of sensory input to NWR as previously found in the rat and 2) if mice strains with a poor learning capacity in various behavioural tests, associated with deficient long term potention, also exhibit poor adaptation of NWR. The organisation of the NWR system in two adult wild type mouse strains with normal long term potentiation (LTP) in hippocampus and two adult wild type mouse strains exhibiting deficiencies in corresponding LTP were used and compared to previous results in the rat. Receptive fields of reflexes in single hindlimb muscles were mapped with CO2 laser heat pulses. Results While the spatial organisation of the nociceptive receptive fields in mice with normal LTP were very similar to those in rats, the LTP impaired strains exhibited receptive fields of NWRs with aberrant sensitivity distributions. However, no difference was found in NWR thresholds or onset C-fibre latencies suggesting that the mechanisms determining general reflex sensitivity and somatosensory imprinting are different. Conclusion Our results thus confirm that sensory encoding in mice and rat NWR is similar, provided that mice strains with a good learning capability are studied and raise the possibility that LTP like mechanisms are involved in somatosensory imprinting. PMID:18495020

  13. Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory.

    PubMed

    Winkle, Cortney C; Olsen, Reid H J; Kim, Hyojin; Moy, Sheryl S; Song, Juan; Gupton, Stephanie L

    2016-05-04

    During hippocampal development, newly born neurons migrate to appropriate destinations, extend axons, and ramify dendritic arbors to establish functional circuitry. These developmental stages are recapitulated in the dentate gyrus of the adult hippocampus, where neurons are continuously generated and subsequently incorporate into existing, local circuitry. Here we demonstrate that the E3 ubiquitin ligase TRIM9 regulates these developmental stages in embryonic and adult-born mouse hippocampal neurons in vitro and in vivo Embryonic hippocampal and adult-born dentate granule neurons lacking Trim9 exhibit several morphological defects, including excessive dendritic arborization. Although gross anatomy of the hippocampus was not detectably altered by Trim9 deletion, a significant number of Trim9(-/-) adult-born dentate neurons localized inappropriately. These morphological and localization defects of hippocampal neurons in Trim9(-/-) mice were associated with extreme deficits in spatial learning and memory, suggesting that TRIM9-directed neuronal morphogenesis may be involved in hippocampal-dependent behaviors. Appropriate generation and incorporation of adult-born neurons in the dentate gyrus are critical for spatial learning and memory and other hippocampal functions. Here we identify the brain-enriched E3 ubiquitin ligase TRIM9 as a novel regulator of embryonic and adult hippocampal neuron shape acquisition and hippocampal-dependent behaviors. Genetic deletion of Trim9 elevated dendritic arborization of hippocampal neurons in vitro and in vivo Adult-born dentate granule cells lacking Trim9 similarly exhibited excessive dendritic arborization and mislocalization of cell bodies in vivo These cellular defects were associated with severe deficits in spatial learning and memory. Copyright © 2016 the authors 0270-6474/16/364940-19$15.00/0.

  14. Bending and coupling losses in terahertz wire waveguides.

    PubMed

    Astley, Victoria; Scheiman, Julianna; Mendis, Rajind; Mittleman, Daniel M

    2010-02-15

    We present an experimental study of several common perturbations of wire waveguides for terahertz pulses. Sommerfeld waves retain significant signal strength and bandwidth even with large gaps in the wire, exhibiting more efficient recoupling at higher frequencies. We also describe a detailed study of bending losses. For a given turn angle, we observe an optimum radius of curvature that minimizes the overall propagation loss. These results emphasize the impact of the distortion of the spatial mode on the radiative bend loss.

  15. Quantifying Landscape Spatial Pattern: What Is the State of the Art?

    Treesearch

    Eric J. Gustafson

    1998-01-01

    Landscape ecology is based on the premise that there are strong links between ecological pattern and ecological function and process. Ecological systems are spatially heterogeneous, exhibiting consid-erable complexity and variability in time and space. This variability is typically represented by categorical maps or by a collection of samples taken at specific spatial...

  16. National review of ambient air toxics observations.

    PubMed

    Strum, Madeleine; Scheffe, Richard

    2016-02-01

    Ambient air observations of hazardous air pollutant (HAPs), also known as air toxics, derived from routine monitoring networks operated by states, local agencies, and tribes (SLTs), are analyzed to characterize national concentrations and risk across the nation for a representative subset of the 187 designated HAPs. Observations from the National Air Toxics Trend Sites (NATTS) network of 27 stations located in most major urban areas of the contiguous United States have provided a consistent record of HAPs that have been identified as posing the greatest risk since 2003 and have also captured similar concentration patterns of nearly 300 sites operated by SLTs. Relatively high concentration volatile organic compounds (VOCs) such as benzene, formaldehyde, and toluene exhibit the highest annual average concentration levels, typically ranging from 1 to 5 µg/m(3). Halogenated (except for methylene chloride) and semivolatile organic compounds (SVOCs) and metals exhibit concentrations typically 2-3 orders of magnitude lower. Formaldehyde is the highest national risk driver based on estimated cancer risk and, nationally, has not exhibited significant changes in concentration, likely associated with the large pool of natural isoprene and formaldehyde emissions. Benzene, toluene, ethylbenzene, and 1,3-butadiene are ubiquitous VOC HAPs with large mobile source contributions that continue to exhibit declining concentrations over the last decade. Common chlorinated organic compounds such as ethylene dichloride and methylene chloride exhibit increasing concentrations. The variety of physical and chemical attributes and measurement technologies across 187 HAPs result in a broad range of method detection limits (MDLs) and cancer risk thresholds that challenge confidence in risk results for low concentration HAPs with MDLs near or greater than risk thresholds. From a national monitoring network perspective, the ability of the HAPs observational database to characterize the multiple pollutant and spatial scale patterns influencing exposure is severely limited and positioned to benefit by leveraging a variety of emerging measurement technologies. Ambient air toxics observation networks have limited ability to characterize the broad suite of hazardous air pollutants (HAPs) that affect exposures across multiple spatial scales. While our networks are best suited to capture major urban-scale signals of ubiquitous volatile organic compound HAPs, incorporation of sensing technologies that address regional and local-scale exposures should be pursued to address major gaps in spatial resolution. Caution should be exercised in interpreting HAPs observations based on data proximity to minimum detection limit and risk thresholds.

  17. Effects of aerosol-vapor JP-8 jet fuel on the functional observational battery, and learning and memory in the rat.

    PubMed

    Baldwin, C M; Houston, F P; Podgornik, M N; Young, R S; Barnes, C A; Witten, M L

    2001-01-01

    To determine whether JP-8 jet fuel affects parameters of the Functional Observational Battery (FOB), visual discrimination, or spatial learning and memory, the authors exposed groups of male Fischer Brown Norway hybrid rats for 28 d to aerosol/vapor-delivered JP-8, or to JP-8 followed by 15 min of aerosolized substance P analogue, or to sham-confined fresh room air. Behavioral testing was accomplished with the U.S. Environmental Protection Agency's Functional Observational Battery. The authors used the Morris swim task to test visual and spatial learning and memory testing. The spatial test included examination of memory for the original target location following 15 d of JP-8 exposure, as well as a 3-d new target location learning paradigm implemented the day that followed the final day of exposure. Only JP-8 exposed animals had significant weight loss by the 2nd week of exposure compared with JP-8 with substance P and control rats; this finding compares with those of prior studies of JP-8 jet fuel. Rats exposed to JP-8 with or without substance P exhibited significantly greater rearing and less grooming behavior over time than did controls during Functional Observational Battery open-field testing. Exposed rats also swam significantly faster than controls during the new target location training and testing, thus supporting the increased activity noted during Functional Observational Battery testing. There were no significant differences between the exposed and control groups' performances during acquisition, retention, or learning of the new platform location in either the visual discrimination or spatial version of the Morris swim task. The data suggest that although visual discrimination and spatial learning and memory were not disrupted by JP-8 exposure, arousal indices and activity measures were distinctly different in these animals.

  18. Effects of Monomer Structure on Their Organization and Polymerization in a Smectic Liquid Crystal

    PubMed

    Guymon; Hoggan; Clark; Rieker; Walba; Bowman

    1997-01-03

    Photopolymerizable diacrylate monomers dissolved in fluid-layer smectic A and smectic C liquid crystal (LC) hosts exhibited significant spatial segregation and orientation that depend strongly on monomer structure. Small, flexible monomers such as 1,6-hexanediol diacrylate (HDDA) oriented parallel to the smectic layers and intercalated, whereas rod-shaped mesogen-like monomers such as 1,4-di-(4-(6-acryloyloxyhexyloxy)benzoyloxy)-2-methylbenzene (C6M) oriented normal to the smectic layers and collected within them. Such spatial segregation caused by the smectic layering dramatically enhanced photopolymerization rates; for HDDA, termination rates were reduced, whereas for C6M, both the termination and propagation rates were increased. These polymerization precursor structures suggest novel materials-design paradigms for gel LCs and nanophase-separated polymer systems.

  19. 2D image of local density and magnetic fluctuations from line-integrated interferometry-polarimetry measurements.

    PubMed

    Lin, L; Ding, W X; Brower, D L

    2014-11-01

    Combined polarimetry-interferometry capability permits simultaneous measurement of line-integrated density and Faraday effect with fast time response (∼1 μs) and high sensitivity. Faraday effect fluctuations with phase shift of order 0.05° associated with global tearing modes are resolved with an uncertainty ∼0.01°. For physics investigations, local density fluctuations are obtained by inverting the line-integrated interferometry data. The local magnetic and current density fluctuations are then reconstructed using a parameterized fit of the polarimetry data. Reconstructed 2D images of density and magnetic field fluctuations in a poloidal cross section exhibit significantly different spatial structure. Combined with their relative phase, the magnetic-fluctuation-induced particle transport flux and its spatial distribution are resolved.

  20. 2D image of local density and magnetic fluctuations from line-integrated interferometry-polarimetry measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, L., E-mail: lianglin@ucla.edu; Ding, W. X.; Brower, D. L.

    2014-11-15

    Combined polarimetry-interferometry capability permits simultaneous measurement of line-integrated density and Faraday effect with fast time response (∼1 μs) and high sensitivity. Faraday effect fluctuations with phase shift of order 0.05° associated with global tearing modes are resolved with an uncertainty ∼0.01°. For physics investigations, local density fluctuations are obtained by inverting the line-integrated interferometry data. The local magnetic and current density fluctuations are then reconstructed using a parameterized fit of the polarimetry data. Reconstructed 2D images of density and magnetic field fluctuations in a poloidal cross section exhibit significantly different spatial structure. Combined with their relative phase, the magnetic-fluctuation-induced particlemore » transport flux and its spatial distribution are resolved.« less

  1. Coronal energy distribution and X-ray activity in the small scale magnetic field of the quiet sun

    NASA Technical Reports Server (NTRS)

    Habbal, S. R.

    1992-01-01

    The energy distribution in the small-scale magnetic field that pervades the solar surface, and its relationship to X-ray/coronal activity are discussed. The observed emission from the small scale structures, at temperatures characteristic of the chromosphere, transition region and corona, emanates from the boundaries of supergranular cells, within coronal bright points. This emission is characterized by a strong temporal and spatial variability with no definite pattern. The analysis of simultaneous, multiwavelength EUV observations shows that the spatial density of the enhanced as well as variable emission from the small scale structures exhibits a pronounced temperature dependence with significant maxima at 100,000 and 1,000,000 K. Within the limits of the spatial (1-5 arcsec) and temporal (1-5 min) resolution of data available at present, the observed variability in the small scale structure cannot account for the coroal heating of the quiet sun. The characteristics of their emission are more likely to be an indicator of the coronal heating mechanisms.

  2. Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor

    PubMed Central

    Chang, Eric H.; Volpe, Bruce T.; Mackay, Meggan; Aranow, Cynthia; Watson, Philip; Kowal, Czeslawa; Storbeck, Justin; Mattis, Paul; Berlin, RoseAnn; Chen, Huiyi; Mader, Simone; Huerta, Tomás S.; Huerta, Patricio T.; Diamond, Betty

    2015-01-01

    Patients with systemic lupus erythematosus (SLE) experience cognitive abnormalities in multiple domains including processing speed, executive function, and memory. Here we show that SLE patients carrying antibodies that bind DNA and the GluN2A and GluN2B subunits of the N-methyl-d-aspartate receptor (NMDAR), termed DNRAbs, displayed a selective impairment in spatial recall. Neural recordings in a mouse model of SLE, in which circulating DNRAbs penetrate the hippocampus, revealed that CA1 place cells exhibited a significant expansion in place field size. Structural analysis showed that hippocampal pyramidal cells had substantial reductions in their dendritic processes and spines. Strikingly, these abnormalities became evident at a time when DNRAbs were no longer detectable in the hippocampus. These results suggest that antibody-mediated neurocognitive impairments may be highly specific, and that spatial cognition may be particularly vulnerable to DNRAb-mediated structural and functional injury to hippocampal cells that evolves after the triggering insult is no longer present. PMID:26286205

  3. Reversing storm hotspots on sandy beaches: Spatial and temporal characteristics

    USGS Publications Warehouse

    List, J.H.; Farris, A.S.; Sullivan, C.

    2006-01-01

    Coastal erosion hotspots are defined as sections of coast that exhibit significantly higher rates of erosion than adjacent areas. This paper describes the spatial and temporal characteristics of a recently identified type of coastal erosion hotspot, which forms in response to storms on uninterrupted sandy coasts largely free from human intervention. These are referred to here as reversing storm hotspots because the erosion is reversed by accretion of a similar magnitude to the storm-induced erosion. The accretion occurs within a few days or weeks of fair weather after the storm. Reversing storm hotspots observed here, on two US east coast beaches, have a longshore length averaging 3.86 km, a cross-shore excursion (magnitude of erosion or accretion) averaging 15.4 m, and a time scale of days to weeks associated with individual storm events. These spatial and temporal scales clearly distinguish reversing storm hotspots from previously described forms of longshore variability in erosion, including those attributed to several types of shoreline undulations and hotspots associated with long-term shoreline change. 

  4. Fuzzy-based assessment of groundwater intrinsic vulnerability of a volcanic aquifer in the Chilean Andean Valley.

    PubMed

    Duhalde, Denisse J; Arumí, José L; Oyarzún, Ricardo A; Rivera, Diego A

    2018-06-11

    A fuzzy logic approach has been proposed to face the uncertainty caused by sparse data in the assessment of the intrinsic vulnerability of a groundwater system with parametric methods in Las Trancas Valley, Andean Mountain, south-central Chile, a popular touristic place in Chile, but lacking of a centralized drinking and sewage water public systems; this situation is a potentially source of groundwater pollution. Based on DRASTIC, GOD, and EKv and the expert knowledge of the study area, the Mamdani fuzzy approach was generated and the spatial data were processed by ArcGIS. The groundwater system exhibited areas with high, medium, and low intrinsic vulnerability indices. The fuzzy approach results were compared with traditional methods results, which, in general, have shown a good spatial agreement even though significant changes were also identified in the spatial distribution of the indices. The Mamdani logic approach has shown to be a useful and practical tool to assess the intrinsic vulnerability of an aquifer under sparse data conditions.

  5. Imaging Intratumor Heterogeneity: Role in Therapy Response, Resistance, and Clinical Outcome

    PubMed Central

    O’Connor, James P.B.; Rose, Chris J.; Waterton, John C.; Carano, Richard A.D.; Parker, Geoff J.M.; Jackson, Alan

    2014-01-01

    Tumors exhibit genomic and phenotypic heterogeneity which has prognostic significance and may influence response to therapy. Imaging can quantify the spatial variation in architecture and function of individual tumors through quantifying basic biophysical parameters such as density or MRI signal relaxation rate; through measurements of blood flow, hypoxia, metabolism, cell death and other phenotypic features; and through mapping the spatial distribution of biochemical pathways and cell signaling networks. These methods can establish whether one tumor is more or less heterogeneous than another and can identify sub-regions with differing biology. In this article we review the image analysis methods currently used to quantify spatial heterogeneity within tumors. We discuss how analysis of intratumor heterogeneity can provide benefit over more simple biomarkers such as tumor size and average function. We consider how imaging methods can be integrated with genomic and pathology data, rather than be developed in isolation. Finally, we identify the challenges that must be overcome before measurements of intratumoral heterogeneity can be used routinely to guide patient care. PMID:25421725

  6. Spatial dynamics of two oriental fruit fly (Diptera: Tephritidae) parasitoids, Fopius arisanus and Diachasmimorpha longicaudata (Hymenoptera: Braconidae), in a Guava orchard in Hawaii.

    PubMed

    Vargas, Roger I; Stark, John D; Banks, John; Leblanc, Luc; Manoukis, Nicholas C; Peck, Steven

    2013-10-01

    We examined spatial patterns of both sexes of oriental fruit fly, Bactrocera dorsalis (Hendel), and its two most abundant parasitoids, Fopius arisanus (Sonan) and Diachasmimorpha longicaudata (Ashmead) in a commercial guava (Psidium guajava L.) orchard. Oriental fruit fly spatial patterns were initially random, but became highly aggregated with host fruit ripening and the subsequent colonization of, first, F. arisanus (egg-pupal parasitoid) and, second, D. longicaudata (larval-pupal parasitoid). There was a significant positive relationship between populations of oriental fruit fly and F. arisanus during each of the F. arisanus increases, a pattern not exhibited between oriental fruit fly and D. longicaudata. Generally, highest total numbers of males and females (oriental fruit fly, F. arisanus, and D. longicaudata) occurred on or about the same date. There was a significant positive correlation between male and female populations of all three species; we measured a lag of 2-4 wk between increases of female F. arisanus and conspecific males. There was a similar trend in one of the two years for the second most abundant species, D. longicaudata, but no sign of a time lag between the sexes for oriental fruit fly. Spatially, we found a significant positive relationship between numbers of F. arisanus in blocks and the average number in adjoining blocks. We did not find the same effect for oriental fruit fly and D. longicaudata, possibly a result of lower overall numbers of the latter two species or less movement of F. arisanus within the field.

  7. Anthropogenic heat flux: advisable spatial resolutions when input data are scarce

    NASA Astrophysics Data System (ADS)

    Gabey, A. M.; Grimmond, C. S. B.; Capel-Timms, I.

    2018-02-01

    Anthropogenic heat flux (QF) may be significant in cities, especially under low solar irradiance and at night. It is of interest to many practitioners including meteorologists, city planners and climatologists. QF estimates at fine temporal and spatial resolution can be derived from models that use varying amounts of empirical data. This study compares simple and detailed models in a European megacity (London) at 500 m spatial resolution. The simple model (LQF) uses spatially resolved population data and national energy statistics. The detailed model (GQF) additionally uses local energy, road network and workday population data. The Fractions Skill Score (FSS) and bias are used to rate the skill with which the simple model reproduces the spatial patterns and magnitudes of QF, and its sub-components, from the detailed model. LQF skill was consistently good across 90% of the city, away from the centre and major roads. The remaining 10% contained elevated emissions and "hot spots" representing 30-40% of the total city-wide energy. This structure was lost because it requires workday population, spatially resolved building energy consumption and/or road network data. Daily total building and traffic energy consumption estimates from national data were within ± 40% of local values. Progressively coarser spatial resolutions to 5 km improved skill for total QF, but important features (hot spots, transport network) were lost at all resolutions when residential population controlled spatial variations. The results demonstrate that simple QF models should be applied with conservative spatial resolution in cities that, like London, exhibit time-varying energy use patterns.

  8. Spatial impacts of inorganic ligand availability and localized microbial community structure on mitigation of zinc laden mine water in sulfate-reducing bioreactors.

    PubMed

    Drennan, Dina M; Almstrand, Robert; Ladderud, Jeffrey; Lee, Ilsu; Landkamer, Lee; Figueroa, Linda; Sharp, Jonathan O

    2017-05-15

    Sulfate-reducing bioreactors (SRBRs) represent a passive, sustainable, and long-term option for mitigating mining influenced water (MIW) during release. Here we investigate spatial zinc precipitation profiles as influenced by substrate differentiation, inorganic ligand availability (inorganic carbon and sulfide), and microbial community structure in pilot-scale SRBR columns fed with sulfate and zinc-rich MIW. Through a combination of aqueous sampling, geochemical digests, electron microscopy and energy-dispersive x-ray spectroscopy, we were able to delineate zones of enhanced zinc removal, identify precipitates of varying stability, and discern the temporal and spatial evolution of zinc, sulfur, and calcium associations. These geochemical insights revealed spatially variable immobilization regimes between SRBR columns that could be further contrasted as a function of labile (alfalfa-dominated) versus recalcitrant (woodchip-dominated) solid-phase substrate content. Both column subsets exhibited initial zinc removal as carbonates; however precipitation in association with labile substrates was more pronounced and dominated by metal-sulfide formation in the upper portions of the down flow columns with micrographs visually suggestive of sphalerite (ZnS). In contrast, a more diffuse and lower mass of zinc precipitation in the presence of gypsum-like precipitates occurred within the more recalcitrant column systems. While removal and sulfide-associated precipitation were spatially variable, whole bacterial community structure (ANOSIM) and diversity estimates were comparatively homogeneous. However, two phyla exhibited a potentially selective relationship with a significant positive correlation between the ratio of Firmicutes to Bacteroidetes and sulfide-bound zinc. Collectively these biogeochemical insights indicate that depths of maximal zinc sulfide precipitation are temporally dynamic, influenced by substrate composition and broaden our understanding of bio-immobilized zinc species, microbial interactions and potential operational and monitoring tools in these types of passive bioreactors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Capabilities and Limitations of Space-Borne Passive Remote Sensing of Dust

    NASA Technical Reports Server (NTRS)

    Kalashnikova, Olga

    2008-01-01

    Atmospheric dust particles have significant effects on the climate and the environment and despite notable recent advances in modeling and observation, wind-blown dust radiative effects remain poorly quantified in both magnitude and sign [IPCC, 2001]. To address this issue, many scientists are using passive satellite observations to study dust properties and to constrain emission/transport models, because the information provided is both time-resolved and global in coverage. In order to assess the effects of individual dust outbreaks on atmospheric radiation and circulation, relatively high temporal resolution (of the order of hours or days) is required in the observational data. Data should also be available over large geographical areas, as dust clouds may cover hundreds of thousands of square kilometers and will exhibit significant spatial variation in their vertical structure, composition and optical properties, both between and within dust events. Spatial and temporal data continuity is necessary if the large-scale impact of dust loading on climate over periods ranging from hours to months is to be assessed.

  10. Brain oscillations track the formation of episodic memories in the real world.

    PubMed

    Griffiths, Benjamin; Mazaheri, Ali; Debener, Stefan; Hanslmayr, Simon

    2016-12-01

    Despite the well-known influence of environmental context on episodic memory, little has been done to increase contextual richness within the lab. This leaves a blind spot lingering over the neuronal correlates of episodic memory formation in day-to-day life. To address this, we presented participants with a series of words to memorise along a pre-designated route across campus while a mobile EEG system acquired ongoing neural activity. Replicating lab-based subsequent memory effects (SMEs), we identified significant low to mid frequency power decreases (<30Hz), including beta power decreases over the left inferior frontal gyrus. When investigating the oscillatory correlates of temporal and spatial context binding, we found that items strongly bound to spatial context exhibited significantly greater theta power decreases than items strongly bound to temporal context. These findings expand upon lab-based studies by demonstrating the influence of real world contextual factors that underpin memory formation. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Frontoparietal regions may become hypoactive after intermittent theta burst stimulation over the contralateral homologous cortex in humans.

    PubMed

    He, Xiaofei; Lan, Yue; Xu, Guangqing; Mao, Yurong; Chen, Zhenghong; Huang, Dongfeng; Pei, Zhong

    2013-12-01

    Brain injury to the dorsal frontoparietal networks, including the posterior parietal cortex (PPC) and dorsolateral prefrontal cortex (DLPFC), commonly cause spatial neglect. However, the interaction of these different regions in spatial attention is unclear. The aim of the present study was to investigate whether hyperexcitable neural networks can cause an abnormal interhemispheric inhibition. The Attention Network Test was used to test subjects following intermittent theta burst stimulation (iTBS) to the left or right frontoparietal networks. During the Attention Network Test task, all subjects tolerated each conditioning iTBS without any obvious iTBS-related side effects. Subjects receiving real-right-PPC iTBS showed significant enhancement in both alerting and orienting efficiency compared with those receiving either sham-right-PPC iTBS or real-left-PPC iTBS. Moreover, subjects exposed to the real-right-DLPFC iTBS exhibited significant improvement in both alerting and executive control efficiency, compared with those exposed to either the sham-right-DLPFC or real-left-DLPFC conditioning. Interestingly, compared with subjects exposed to the sham-left-PPC stimuli, subjects exposed to the real-left-PPC iTBS had a significant deficit in the orienting index. The present study indicates that iTBS over the contralateral homologous cortex may induce the hypoactivity of the right PPC through interhemispheric competition in spatial orienting attention.

  12. Population genetic structure and its implications for adaptive variation in memory and the hippocampus on a continental scale in food-caching black-capped chickadees.

    PubMed

    Pravosudov, V V; Roth, T C; Forister, M L; Ladage, L D; Burg, T M; Braun, M J; Davidson, B S

    2012-09-01

    Food-caching birds rely on stored food to survive the winter, and spatial memory has been shown to be critical in successful cache recovery. Both spatial memory and the hippocampus, an area of the brain involved in spatial memory, exhibit significant geographic variation linked to climate-based environmental harshness and the potential reliance on food caches for survival. Such geographic variation has been suggested to have a heritable basis associated with differential selection. Here, we ask whether population genetic differentiation and potential isolation among multiple populations of food-caching black-capped chickadees is associated with differences in memory and hippocampal morphology by exploring population genetic structure within and among groups of populations that are divergent to different degrees in hippocampal morphology. Using mitochondrial DNA and 583 AFLP loci, we found that population divergence in hippocampal morphology is not significantly associated with neutral genetic divergence or geographic distance, but instead is significantly associated with differences in winter climate. These results are consistent with variation in a history of natural selection on memory and hippocampal morphology that creates and maintains differences in these traits regardless of population genetic structure and likely associated gene flow. Published 2012. This article is a US Government work and is in the public domain in the USA.

  13. Feasibility and utility of mapping disease risk at the neighbourhood level within a Canadian public health unit: an ecological study

    PubMed Central

    2010-01-01

    Background We conducted spatial analyses to determine the geographic variation of cancer at the neighbourhood level (dissemination areas or DAs) within the area of a single Ontario public health unit, Wellington-Dufferin-Guelph, covering a population of 238,326 inhabitants. Cancer incidence data between 1999 and 2003 were obtained from the Ontario Cancer Registry and were geocoded down to the level of DA using the enhanced Postal Code Conversion File. The 2001 Census of Canada provided information on the size and age-sex structure of the population at the DA level, in addition to information about selected census covariates, such as average neighbourhood income. Results Age standardized incidence ratios for cancer and the prevalence of census covariates were calculated for each of 331 dissemination areas in Wellington-Dufferin-Guelph. The standardized incidence ratios (SIR) for cancer varied dramatically across the dissemination areas. However, application of the Moran's I statistic, a popular index of spatial autocorrelation, suggested significant spatial patterns for only two cancers, lung and prostate, both in males (p < 0.001 and p = 0.002, respectively). Employing Bayesian hierarchical models, areas in the urban core of the City of Guelph had significantly higher SIRs for male lung cancer than the remainder of Wellington-Dufferin-Guelph; and, neighbourhoods in the urban and surrounding rural areas of Orangeville exhibited significantly higher SIRs for prostate cancer. After adjustment for age and spatial dependence, average household income attenuated much of the spatial pattern of lung cancer, but not of prostate cancer. Conclusion This paper demonstrates the feasibility and utility of a systematic approach to identifying neighbourhoods, within the area served by a public health unit, that have significantly higher risks of cancer. This exploratory, ecologic study suggests several hypotheses for these spatial patterns that warrant further investigations. To the best of our knowledge, this is the first Canadian study published in the peer-reviewed literature estimating the risk of relatively rare public health outcomes at a very small areal level, namely dissemination areas. PMID:20459738

  14. Cerebral specialization for spatial processing in adults with Down syndrome.

    PubMed

    Elliott, D; Pollock, B J; Chua, R; Weeks, D J

    1995-05-01

    Cerebral specialization for spatial processing in adults with Down syndrome was examined. In the first experiment, both control and right-handed subjects with Down syndrome exhibited no lateral advantage in a dihaptic shape-matching task, whereas left-handed subjects with Down syndrome displayed an expected left-hand advantage. In a visual field dot enumeration task in the second experiment, all groups exhibited left-field superiority. Thus, atypical cerebral organization of function in adults with Down syndrome appears to be confined to speech perception (Elliott & Weeks, 1993).

  15. Applications of Fractal Analytical Techniques in the Estimation of Operational Scale

    NASA Technical Reports Server (NTRS)

    Emerson, Charles W.; Quattrochi, Dale A.

    2000-01-01

    The observational scale and the resolution of remotely sensed imagery are essential considerations in the interpretation process. Many atmospheric, hydrologic, and other natural and human-influenced spatial phenomena are inherently scale dependent and are governed by different physical processes at different spatial domains. This spatial and operational heterogeneity constrains the ability to compare interpretations of phenomena and processes observed in higher spatial resolution imagery to similar interpretations obtained from lower resolution imagery. This is a particularly acute problem, since longterm global change investigations will require high spatial resolution Earth Observing System (EOS), Landsat 7, or commercial satellite data to be combined with lower resolution imagery from older sensors such as Landsat TM and MSS. Fractal analysis is a useful technique for identifying the effects of scale changes on remotely sensed imagery. The fractal dimension of an image is a non-integer value between two and three which indicates the degree of complexity in the texture and shapes depicted in the image. A true fractal surface exhibits self-similarity, a property of curves or surfaces where each part is indistinguishable from the whole, or where the form of the curve or surface is invariant with respect to scale. Theoretically, if the digital numbers of a remotely sensed image resemble an ideal fractal surface, then due to the self-similarity property, the fractal dimension of the image will not vary with scale and resolution, and the slope of the fractal dimension-resolution relationship would be zero. Most geographical phenomena, however, are not self-similar at all scales, but they can be modeled by a stochastic fractal in which the scaling properties of the image exhibit patterns that can be described by statistics such as area-perimeter ratios and autocovariances. Stochastic fractal sets relax the self-similarity assumption and measure many scales and resolutions to represent the varying form of a phenomenon as the pixel size is increased in a convolution process. We have observed that for images of homogeneous land covers, the fractal dimension varies linearly with changes in resolution or pixel size over the range of past, current, and planned space-borne sensors. This relationship differs significantly in images of agricultural, urban, and forest land covers, with urban areas retaining the same level of complexity, forested areas growing smoother, and agricultural areas growing more complex as small pixels are aggregated into larger, mixed pixels. Images of scenes having a mixture of land covers have fractal dimensions that exhibit a non-linear, complex relationship to pixel size. Measuring the fractal dimension of a difference image derived from two images of the same area obtained on different dates showed that the fractal dimension increased steadily, then exhibited a sharp decrease at increasing levels of pixel aggregation. This breakpoint of the fractal dimension/resolution plot is related to the spatial domain or operational scale of the phenomenon exhibiting the predominant visible difference between the two images (in this case, mountain snow cover). The degree to which an image departs from a theoretical ideal fractal surface provides clues as to how much information is altered or lost in the processes of rescaling and rectification. The measured fractal dimension of complex, composite land covers such as urban areas also provides a useful textural index that can assist image classification of complex scenes.

  16. Sex, estradiol, and spatial memory in a food-caching corvid.

    PubMed

    Rensel, Michelle A; Ellis, Jesse M S; Harvey, Brigit; Schlinger, Barney A

    2015-09-01

    Estrogens significantly impact spatial memory function in mammalian species. Songbirds express the estrogen synthetic enzyme aromatase at relatively high levels in the hippocampus and there is evidence from zebra finches that estrogens facilitate performance on spatial learning and/or memory tasks. It is unknown, however, whether estrogens influence hippocampal function in songbirds that naturally exhibit memory-intensive behaviors, such as cache recovery observed in many corvid species. To address this question, we examined the impact of estradiol on spatial memory in non-breeding Western scrub-jays, a species that routinely participates in food caching and retrieval in nature and in captivity. We also asked if there were sex differences in performance or responses to estradiol. Utilizing a combination of an aromatase inhibitor, fadrozole, with estradiol implants, we found that while overall cache recovery rates were unaffected by estradiol, several other indices of spatial memory, including searching efficiency and efficiency to retrieve the first item, were impaired in the presence of estradiol. In addition, males and females differed in some performance measures, although these differences appeared to be a consequence of the nature of the task as neither sex consistently out-performed the other. Overall, our data suggest that a sustained estradiol elevation in a food-caching bird impairs some, but not all, aspects of spatial memory on an innate behavioral task, at times in a sex-specific manner. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. SEX, ESTRADIOL, AND SPATIAL MEMORY IN A FOOD-CACHING CORVID

    PubMed Central

    Rensel, Michelle A.; Ellis, Jesse M.S.; Harvey, Brigit; Schlinger, Barney A.

    2015-01-01

    Estrogens significantly impact spatial memory function in mammalian species. Songbirds express the estrogen synthetic enzyme aromatase at relatively high levels in the hippocampus and there is evidence from zebra finches that estrogens facilitate performance on spatial learning and/or memory tasks. It is unknown, however, whether estrogens influence hippocampal function in songbirds that naturally exhibit memory-intensive behaviors, such as cache recovery observed in many corvid species. To address this question, we examined the impact of estradiol on spatial memory in non-breeding Western scrub-jays, a species that routinely participates in food caching and retrieval in nature and in captivity. We also asked if there were sex differences in performance or responses to estradiol. Utilizing a combination of an aromatase inhibitor, fadrozole, with estradiol implants, we found that while overall cache recovery rates were unaffected by estradiol, several other indices of spatial memory, including searching efficiency and efficiency to retrieve the first item, were impaired in the presence of estradiol. In addition, males and females differed in some performance measures, although these differences appeared to be a consequence of the nature of the task as neither sex consistently out-performed the other. Overall, our data suggest that a sustained estradiol elevation in a food-caching bird impairs some, but not all, aspects of spatial memory on an innate behavioral task, at times in a sex-specific manner. PMID:26232613

  18. Substructures and Tidal Distortions in the Magellanic Stellar Periphery

    NASA Astrophysics Data System (ADS)

    Mackey, Dougal; Koposov, Sergey; Da Costa, Gary; Belokurov, Vasily; Erkal, Denis; Kuzma, Pete

    2018-05-01

    We use a new panoramic imaging survey conducted with the Dark Energy Camera to map the stellar fringes of the Large and Small Magellanic Clouds (LMC/SMC) to extremely low surface brightness V ≈ 32 mag arcsec‑2. Our results starkly illustrate the closely interacting nature of the LMC–SMC pair. We show that the outer LMC disk is strongly distorted, exhibiting an irregular shape, evidence for warping, and significant truncation on the side facing the SMC. Large diffuse stellar substructures are present both to the north and south of the LMC, and in the inter-Cloud region. At least one of these features appears as co-spatial with the bridge of RR Lyrae stars that connects the Clouds. The SMC is highly disturbed; we confirm the presence of tidal tails, as well as a large line-of-sight depth on the side closest to the LMC. Young, intermediate-age, and ancient stellar populations in the SMC exhibit strikingly different spatial distributions. In particular, those with ages ∼1.5–4 Gyr exhibit a spheroidal distribution with a centroid offset from that of the oldest stars by several degrees toward the LMC. We speculate that the gravitational influence of the LMC may already have been perturbing the gaseous component of the SMC several Gyr ago. With careful modeling, the variety of substructures and tidal distortions evident in the Magellanic periphery should tightly constrain the interaction history of the Clouds.

  19. Biotic Drivers of Spatial Heterogeneity and Implications for River Ecosystems

    NASA Astrophysics Data System (ADS)

    Wohl, Ellen

    2017-04-01

    Rivers throughout the northern hemisphere have been simplified and homogenized by the removal of beavers and instream wood, along with numerous forms of channel engineering and flow regulation. Loss of spatial heterogeneity in river corridors - channels and floodplains - affects downstream fluxes of water, sediment, organic matter, and nutrients, as well as stream metabolism, biomass, and biodiversity. Recent work in streams of the Colorado Rocky Mountains illustrates how the presence of beavers and instream wood can facilitate spatial heterogeneity by creating stable, persistent, multithread channel planform and high channel-floodplain and channel-hyporheic zone connectivity. This spatial heterogeneity facilitates retention of water in pools, floodplain wetlands, and hyporheic storage. Suspended sediment, particulate organic matter (POM), and solutes are also more likely to be retained in these stream segments than in more uniform stream segments with greater downstream conveyance. Retention of POM and solutes equates to greater volumes of organic carbon storage per unit valley length and greater rates of nitrogen uptake. Spatially heterogeneous stream segments also exhibit greater biomass and biodiversity of aquatic macroinvertebrates, salmonid fish, and riparian spiders than do more uniform stream segments. These significant differences in stream form and function are unlikely to be unique to this field area and can provide a conceptual model for understanding and restoring ecosystem functions in other rivers.

  20. Fine-scale spatial distribution of orchid mycorrhizal fungi in the soil of host-rich grasslands.

    PubMed

    Voyron, Samuele; Ercole, Enrico; Ghignone, Stefano; Perotto, Silvia; Girlanda, Mariangela

    2017-02-01

    Mycorrhizal fungi are essential for the survival of orchid seedlings under natural conditions. The distribution of these fungi in soil can constrain the establishment and resulting spatial arrangement of orchids at the local scale, but the actual extent of occurrence and spatial patterns of orchid mycorrhizal (OrM) fungi in soil remain largely unknown. We addressed the fine-scale spatial distribution of OrM fungi in two orchid-rich Mediterranean grasslands by means of high-throughput sequencing of fungal ITS2 amplicons, obtained from soil samples collected either directly beneath or at a distance from adult Anacamptis morio and Ophrys sphegodes plants. Like ectomycorrhizal and arbuscular mycobionts, OrM fungi (tulasnelloid, ceratobasidioid, sebacinoid and pezizoid fungi) exhibited significant horizontal spatial autocorrelation in soil. However, OrM fungal read numbers did not correlate with distance from adult orchid plants, and several of these fungi were extremely sporadic or undetected even in the soil samples containing the orchid roots. Orchid mycorrhizal 'rhizoctonias' are commonly regarded as unspecialized saprotrophs. The sporadic occurrence of mycobionts of grassland orchids in host-rich stands questions the view of these mycorrhizal fungi as capable of sustained growth in soil. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  1. Spatial distribution of diesel transit bus emissions and urban populations: implications of coincidence and scale on exposure.

    PubMed

    Gouge, Brian; Ries, Francis J; Dowlatabadi, Hadi

    2010-09-15

    Macroscale emissions modeling approaches have been widely applied in impact assessments of mobile source emissions. However, these approaches poorly characterize the spatial distribution of emissions and have been shown to underestimate emissions of some pollutants. To quantify the implications of these limitations on exposure assessments, CO, NO(X), and HC emissions from diesel transit buses were estimated at 50 m intervals along a bus rapid transit route using a microscale emissions modeling approach. The impacted population around the route was estimated using census, pedestrian count and transit ridership data. Emissions exhibited significant spatial variability. In intervals near major intersections and bus stops, emissions were 1.6-3.0 times higher than average. The coincidence of these emission hot spots and peaks in pedestrian populations resulted in a 20-40% increase in exposure compared to estimates that assumed homogeneous spatial distributions of emissions and/or populations along the route. An additional 19-30% increase in exposure resulted from the underestimate of CO and NO(X) emissions by macroscale modeling approaches. The results of this study indicate that macroscale modeling approaches underestimate exposure due to poor characterization of the influence of vehicle activity on the spatial distribution of emissions and total emissions.

  2. Exotic singularities and spatially curved loop quantum cosmology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, Parampreet; Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, Ontario N2L 2Y5; Vidotto, Francesca

    2011-03-15

    We investigate the occurrence of various exotic spacelike singularities in the past and the future evolution of k={+-}1 Friedmann-Robertson-Walker model and loop quantum cosmology using a sufficiently general phenomenological model for the equation of state. We highlight the nontrivial role played by the intrinsic curvature for these singularities and the new physics which emerges at the Planck scale. We show that quantum gravity effects generically resolve all strong curvature singularities including big rip and big freeze singularities. The weak singularities, which include sudden and big brake singularities, are ignored by quantum gravity when spatial curvature is negative, as was previouslymore » found for the spatially flat model. Interestingly, for the spatially closed model there exist cases where weak singularities may be resolved when they occur in the past evolution. The spatially closed model exhibits another novel feature. For a particular class of equation of state, this model also exhibits an additional physical branch in loop quantum cosmology, a baby universe separated from the parent branch. Our analysis generalizes previous results obtained on the resolution of strong curvature singularities in flat models to isotropic spacetimes with nonzero spatial curvature.« less

  3. Numerical study of phase conjugation in stimulated Brillouin scattering from an optical waveguide

    NASA Astrophysics Data System (ADS)

    Lehmberg, R. H.

    1983-05-01

    Stimulated Brillouin scattering (SBS) in a multimode optical waveguide is examined, and the parameters that affect the wavefront conjugation fidelity are studied. The nonlinear propagation code is briefly described and the calculated quantities are defined. The parameter study in the low reflectivity limit is described, and the effects of pump depletion are considered. The waveguide produced significantly higher fidelities than the focused configuration, in agreement with several experimental studies. The light scattered back through the phase aberrator exhibited a farfield intenstiy profile closely matching that of the incident beam; however, the nearfield intensity exhibited large and rapid spatial inhomogeneities across the entire aberrator, even for conjugation fidelities as high as 98 percent. In the absence of pump depletion, the fidelity increased with average pump intensity for amplitude gains up to around e to the 10th and then decreased slowly and monotonically with higher intensity. For all cases, pump depletion significantly enhanced the fidelity of the wavefront conjugation by inhibiting the small-scale pulling effect.

  4. Spectral and Polarization Sensitivity of the Dipteran Visual System

    PubMed Central

    McCann, Gilbert D.; Arnett, David W.

    1972-01-01

    Spectral and polarization sensitivity measurements were made at several levels (retina, first and third optic ganglion, cervical connective, behavior) of the dipteran visual nervous system. At all levels, it was possible to reveal contributions from the retinular cell subsystem cells 1 to 6 or the retinular cell subsystem cells 7 and 8 or both. Only retinular cells 1 to 6 were directly studied, and all possessed the same spectral sensitivity characterized by two approximately equal sensitivity peaks at 350 and 480 nm. All units of both the sustaining and on-off variety in the first optic ganglion exhibited the same spectral sensitivity as that of retinular cells 1 to 6. It was possible to demonstrate for motion detection and optomotor responses two different spectral sensitivities depending upon the spatial wavelength of the stimulus. For long spatial wavelengths, the spectral sensitivity agreed with retinular cells 1 to 6; however, the spectral sensitivity at short spatial wavelengths was characterized by a single peak at 465 nm reflecting contributions from the (7, 8) subsystem. Although the two subsystems exhibited different spectral sensitivities, the difference was small and no indication of color discrimination mechanisms was observed. Although all retinular cells 1 to 6 exhibited a preferred polarization plane, sustaining and on-off units did not. Likewise, motion detection and optomotor responses were insensitive to the polarization plane for long spatial wavelength stimuli; however, sensitivity to select polarization planes was observed for short spatial wavelengths. PMID:5027759

  5. Local sensitivity to stimulus orientation and spatial frequency within the receptive fields of neurons in visual area 2 of macaque monkeys

    PubMed Central

    Tao, X.; Zhang, B.; Smith, E. L.; Nishimoto, S.; Ohzawa, I.

    2012-01-01

    We used dynamic dense noise stimuli and local spectral reverse correlation methods to reveal the local sensitivities of neurons in visual area 2 (V2) of macaque monkeys to orientation and spatial frequency within their receptive fields. This minimized the potentially confounding assumptions that are inherent in stimulus selections. The majority of neurons exhibited a relatively high degree of homogeneity for the preferred orientations and spatial frequencies in the spatial matrix of facilitatory subfields. However, about 20% of all neurons showed maximum orientation differences between neighboring subfields that were greater than 25 deg. The neurons preferring horizontal or vertical orientations showed less inhomogeneity in space than the neurons preferring oblique orientations. Over 50% of all units also exhibited suppressive profiles, and those were more heterogeneous than facilitatory profiles. The preferred orientation and spatial frequency of suppressive profiles differed substantially from those of facilitatory profiles, and the neurons with suppressive subfields had greater orientation selectivity than those without suppressive subfields. The peak suppression occurred with longer delays than the peak facilitation. These results suggest that the receptive field profiles of the majority of V2 neurons reflect the orderly convergence of V1 inputs over space, but that a subset of V2 neurons exhibit more complex response profiles having both suppressive and facilitatory subfields. These V2 neurons with heterogeneous subfield profiles could play an important role in the initial processing of complex stimulus features. PMID:22114163

  6. The influence of sex chromosome aneuploidy on brain asymmetry.

    PubMed

    Rezaie, Roozbeh; Daly, Eileen M; Cutter, William J; Murphy, Declan G M; Robertson, Dene M W; DeLisi, Lynn E; Mackay, Clare E; Barrick, Thomas R; Crow, Timothy J; Roberts, Neil

    2009-01-05

    The cognitive deficits present in individuals with sex chromosome aneuploidies suggest that hemispheric differentiation of function is determined by an X-Y homologous gene [Crow (1993); Lancet 342:594-598]. In particular, females with Turner's syndrome (TS) who have only one X-chromosome exhibit deficits of spatial ability whereas males with Klinefelter's syndrome (KS) who possess a supernumerary X-chromosome are delayed in acquiring words. Since spatial and verbal abilities are generally associated with right and left hemispheric function, such deficits may relate to anomalies of cerebral asymmetry. We therefore applied a novel image analysis technique to investigate the relationship between sex chromosome dosage and structural brain asymmetry. Specifically, we tested Crow's prediction that the magnitude of the brain torque (i.e., a combination of rightward frontal and leftward occipital asymmetry) would, as a function of sex chromosome dosage, be respectively decreased in TS women and increased in KS men, relative to genotypically normal controls. We found that brain torque was not significantly different in TS women and KS men, in comparison to controls. However, TS women exhibited significantly increased leftward brain asymmetry, restricted to the posterior of the brain and focused on the superior temporal and parietal-occipital association cortex, while KS men showed a trend for decreased brain asymmetry throughout the frontal lobes. The findings suggest that the number of sex chromosomes influences the development of brain asymmetry not simply to modify the torque but in a complex pattern along the antero-posterior axis. 2008 Wiley-Liss, Inc.

  7. Exploratory Temporal and Spatial Analysis of Myocardial Infarction Hospitalizations in Calgary, Canada

    PubMed Central

    Liu, Xiaoxiao; Bertazzon, Stefania

    2017-01-01

    Spatial and temporal analyses are critical to understand the pattern of myocardial infarction (MI) hospitalizations over space and time, and to identify their underlying determinants. In this paper, we analyze MI hospitalizations in Calgary from 2004 to 2013, stratified by age and gender. First, a seasonal trend decomposition analyzes the seasonality; then a linear regression models the trend component. Moran’s I and hot spot analyses explore the spatial pattern. Though exploratory, results show that most age and gender groups feature a statistically significant decline over the 10 years, consistent with previous studies in Canada. Decline rates vary across ages and genders, with the slowest decline observed for younger males. Each gender exhibits a seasonal pattern with peaks in both winter and summer. Spatially, MI hot spots are identified in older communities, and in socioeconomically and environmentally disadvantaged communities. In the older communities, higher MI rates appear to be more highly associated with demographics. Conversely, worse air quality appears to be locally associated with higher MI incidence in younger age groups. The study helps identify areas of concern, where MI hot spots are identified for younger age groups, suggesting the need for localized public health policies to target local risk factors. PMID:29232910

  8. New quantitative approaches reveal the spatial preference of nuclear compartments in mammalian fibroblasts.

    PubMed

    Weston, David J; Russell, Richard A; Batty, Elizabeth; Jensen, Kirsten; Stephens, David A; Adams, Niall M; Freemont, Paul S

    2015-03-06

    The nuclei of higher eukaryotic cells display compartmentalization and certain nuclear compartments have been shown to follow a degree of spatial organization. To date, the study of nuclear organization has often involved simple quantitative procedures that struggle with both the irregularity of the nuclear boundary and the problem of handling replicate images. Such studies typically focus on inter-object distance, rather than spatial location within the nucleus. The concern of this paper is the spatial preference of nuclear compartments, for which we have developed statistical tools to quantitatively study and explore nuclear organization. These tools combine replicate images to generate 'aggregate maps' which represent the spatial preferences of nuclear compartments. We present two examples of different compartments in mammalian fibroblasts (WI-38 and MRC-5) that demonstrate new knowledge of spatial preference within the cell nucleus. Specifically, the spatial preference of RNA polymerase II is preserved across normal and immortalized cells, whereas PML nuclear bodies exhibit a change in spatial preference from avoiding the centre in normal cells to exhibiting a preference for the centre in immortalized cells. In addition, we show that SC35 splicing speckles are excluded from the nuclear boundary and localize throughout the nucleoplasm and in the interchromatin space in non-transformed WI-38 cells. This new methodology is thus able to reveal the effect of large-scale perturbation on spatial architecture and preferences that would not be obvious from single cell imaging.

  9. CMAQ MODELING FOR AIR TOXICS AT FINE SCALES: A PROTOTYPE STUDY

    EPA Science Inventory

    Toxic air pollutants (TAPs) or hazardous air pollutants (HAPs) exhibit considerable spatial and temporal variability across urban areas. Therefore, the ability of chemical transport models (CTMs), e.g. Community Multi-scale Air Quality (CMAQ), to reproduce the spatial and tempor...

  10. Coupled Effects of Natural and Anthropogenic Controls on Seasonal and Spatial Variations of River Water Quality during Baseflow in a Coastal Watershed of Southeast China

    PubMed Central

    Huang, Jinliang; Huang, Yaling; Zhang, Zhenyu

    2014-01-01

    Surface water samples of baseflow were collected from 20 headwater sub-watersheds which were classified into three types of watersheds (natural, urban and agricultural) in the flood, dry and transition seasons during three consecutive years (2010–2012) within a coastal watershed of Southeast China. Integrating spatial statistics with multivariate statistical techniques, river water quality variations and their interactions with natural and anthropogenic controls were examined to identify the causal factors and underlying mechanisms governing spatiotemporal patterns of water quality. Anthropogenic input related to industrial effluents and domestic wastewater, agricultural activities associated with the precipitation-induced surface runoff, and natural weathering process were identified as the potential important factors to drive the seasonal variations in stream water quality for the transition, flood and dry seasons, respectively. All water quality indicators except SRP had the highest mean concentrations in the dry and transition seasons. Anthropogenic activities and watershed characteristics led to the spatial variations in stream water quality in three types of watersheds. Concentrations of NH4 +-N, SRP, K+, CODMn, and Cl− were generally highest in urban watersheds. NO3 –N Concentration was generally highest in agricultural watersheds. Mg2+ concentration in natural watersheds was significantly higher than that in agricultural watersheds. Spatial autocorrelations analysis showed similar levels of water pollution between the neighboring sub-watersheds exhibited in the dry and transition seasons while non-point source pollution contributed to the significant variations in water quality between neighboring sub-watersheds. Spatial regression analysis showed anthropogenic controls played critical roles in variations of water quality in the JRW. Management implications were further discussed for water resource management. This research demonstrates that the coupled effects of natural and anthropogenic controls involved in watershed processes, contribute to the seasonal and spatial variation of headwater stream water quality in a coastal watershed with high spatial variability and intensive anthropogenic activities. PMID:24618771

  11. Regional vulnerability of the hippocampus to repeated motor activity deprivation.

    PubMed

    Faraji, Jamshid; Soltanpour, Nabiollah; Moeeini, Reza; Hosseini, Seyed Abedin; Pakdel, Shiva; Moharrerie, Alireza; Arjang, Kaveh; Soltanpour, Nasrin; Metz, Gerlinde A S

    2016-03-15

    Spontaneous vertical and horizontal exploratory movements are integral components of rodent behavior. Little is known, however, about the structural and functional consequences of restricted spontaneous exploration. Here, we report two experiments to probe whether restriction in vertical activity (rearing) in rats could induce neuro-hormonal and behavioral disturbances. Rearing movements in rats were deprived for 3h/day for 30 consecutive days by placing the animal into a circular tunnel task. Rats temporarily deprived of rearing behavior showed elevated plasma corticosterone levels but no detectable psychological distress and/or anxiety-related behavior within an elevated plus maze. However, rats emitted a greater number of 22-kHz ultrasonic vocalizations and spent significantly more time vocalizing than controls when deprived of their rearing behavior. Despite intact spatial performance within wet- and dry-land spatial tasks, rearing-deprived rats also exhibited a significant alteration in search strategies within both spatial tasks along with reduced volume and neuron number in the hippocampal subregion CA2. These data suggest a new approach to test the importance of free exploratory behavior in endocrine and structural manifestations. The results support a central role of the CA2 in spontaneous exploratory behavior and vulnerability to psychological stress. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. The relationship between hue discrimination and contrast sensitivity deficits in patients with diabetes mellitus.

    PubMed

    Trick, G L; Burde, R M; Gordon, M O; Santiago, J V; Kilo, C

    1988-05-01

    In an attempt to elucidate more fully the pathophysiologic basis of early visual dysfunction in patients with diabetes mellitus, color vision (hue discrimination) and spatial resolution (contrast sensitivity) were tested in diabetic patients with little or no retinopathy (n = 57) and age-matched visual normals (n = 35). Some evidence of visual dysfunction was observed in 37.8% of the diabetics with no retinopathy and 60.0% of the diabetics with background retinopathy. Although significant hue discrimination and contrast sensitivity deficits were observed in both groups of diabetic patients, contrast sensitivity was abnormal more frequently than hue discrimination. However, only 5.4% of the diabetics with no retinopathy and 10.0% of the diabetics with background retinopathy exhibited both abnormal hue discrimination and abnormal contrast sensitivity. Contrary to previous reports, blue-yellow (B-Y) and red-green (R-G) hue discrimination deficits were observed with approximately equal frequency. In the diabetic group, contrast sensitivity was reduced at all spatial frequencies tested, but for individual diabetic patients, significant deficits were only evident for the mid-range spatial frequencies. Among diabetic patients, the hue discrimination deficits, but not the contrast sensitivity abnormalities, were correlated with the patients' hemoglobin A1 level. A negative correlation between contrast sensitivity at 6.0 cpd and the duration of diabetes also was observed.

  13. A spatial and temporal analysis of paediatric central nervous system infections from 2005 to 2015 in Ho Chi Minh City, Vietnam.

    PubMed

    Ho, N T; Hoang, V M T; Le, N N T; Nguyen, D T; Tran, A; Kaki, D; Tran, P M; Thompson, C N; Ngo, M N Q; Truong, K H; Nguyen, H T; Ha, T M; Nguyen, C V V; Thwaites, G E; Thakur, K T; Hesdorffer, D; Baker, S

    2017-11-01

    Central nervous system infections (CNSI) are a leading cause of death and long-term disability in children. Using ICD-10 data from 2005 to 2015 from three central hospitals in Ho Chi Minh City (HCMC), Vietnam, we exploited generalized additive mixed models (GAMM) to examine the spatial-temporal distribution and spatial and climatic risk factors of paediatric CNSI, excluding tuberculous meningitis, in this setting. From 2005 to 2015, there were 9469 cases of paediatric CNSI; 33% were ⩽1 year old at admission and were mainly diagnosed with presumed bacterial CNSI (BI) (79%), the remainder were >1 year old and mainly diagnosed with presumed non-bacterial CNSI (non-BI) (59%). The urban districts of HCMC in proximity to the hospitals as well as some outer districts had the highest incidences of BI and non-BI; BI incidence was higher in the dry season. Monthly BI incidence exhibited a significant decreasing trend over the study. Both BI and non-BI were significantly associated with lags in monthly average temperature, rainfall, and river water level. Our findings add new insights into this important group of infections in Vietnam, and highlight where resources for the prevention and control of paediatric CNSI should be allocated.

  14. Support vector machine in crash prediction at the level of traffic analysis zones: Assessing the spatial proximity effects.

    PubMed

    Dong, Ni; Huang, Helai; Zheng, Liang

    2015-09-01

    In zone-level crash prediction, accounting for spatial dependence has become an extensively studied topic. This study proposes Support Vector Machine (SVM) model to address complex, large and multi-dimensional spatial data in crash prediction. Correlation-based Feature Selector (CFS) was applied to evaluate candidate factors possibly related to zonal crash frequency in handling high-dimension spatial data. To demonstrate the proposed approaches and to compare them with the Bayesian spatial model with conditional autoregressive prior (i.e., CAR), a dataset in Hillsborough county of Florida was employed. The results showed that SVM models accounting for spatial proximity outperform the non-spatial model in terms of model fitting and predictive performance, which indicates the reasonableness of considering cross-zonal spatial correlations. The best model predictive capability, relatively, is associated with the model considering proximity of the centroid distance by choosing the RBF kernel and setting the 10% of the whole dataset as the testing data, which further exhibits SVM models' capacity for addressing comparatively complex spatial data in regional crash prediction modeling. Moreover, SVM models exhibit the better goodness-of-fit compared with CAR models when utilizing the whole dataset as the samples. A sensitivity analysis of the centroid-distance-based spatial SVM models was conducted to capture the impacts of explanatory variables on the mean predicted probabilities for crash occurrence. While the results conform to the coefficient estimation in the CAR models, which supports the employment of the SVM model as an alternative in regional safety modeling. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Effects of alcoholic beverage treatment on spatial learning and fear memory in mice.

    PubMed

    Hashikawa-Hobara, Narumi; Mishima, Shuta; Nagase, Shotaro; Morita, Keishi; Otsuka, Ami; Hashikawa, Naoya

    2018-04-24

    Although chronic ethanol treatment is known to impair learning and memory, humans commonly consume a range of alcoholic beverages. However, the specific effects of some alcoholic beverages on behavioral performance are largely unknown. The present study compared the effects of a range of alcoholic beverages (plain ethanol solution, red wine, sake and whiskey; with a matched alcohol concentration of 10%) on learning and memory. 6-week-old C57BL6J mice were orally administered alcohol for 7 weeks. The results revealed that red wine treatment exhibited a trend toward improvement of spatial memory and advanced extinction of fear memory. Additionally, red wine treatment significantly increased mRNA levels of brain-derived neurotrophic factor (BDNF) and N-methyl-D-aspartate (NMDA) receptors in mice hippocampus. These results support previous reports that red wine has beneficial effects.

  16. Global Diffusion Pattern and Hot SPOT Analysis of Vaccine-Preventable Diseases

    NASA Astrophysics Data System (ADS)

    Jiang, Y.; Fan, F.; Zanoni, I. Holly; Li, Y.

    2017-10-01

    Spatial characteristics reveal the concentration of vaccine-preventable disease in Africa and the Near East and that disease dispersion is variable depending on disease. The exception is whooping cough, which has a highly variable center of concentration from year to year. Measles exhibited the only statistically significant spatial autocorrelation among all the diseases under investigation. Hottest spots of measles are in Africa and coldest spots are in United States, warm spots are in Near East and cool spots are in Western Europe. Finally, cases of measles could not be explained by the independent variables, including Gini index, health expenditure, or rate of immunization. Since the literature confirms that each of the selected variables is considered determinants of disease dissemination, it is anticipated that the global dataset of disease cases was influenced by reporting bias.

  17. Regional Population Dynamics

    Treesearch

    Andrew Birt

    2011-01-01

    The population dynamics of the southern pine beetle (SPB) exhibit characteristic fluctuations between relatively long endemic and shorter outbreak periods. Populations exhibit complex and hierarchical spatial structure with beetles and larvae aggregating within individual trees, infestations with multiple infested trees, and regional outbreaks that comprise a large...

  18. Spatial distribution patterns of soil mite communities and their relationships with edaphic factors in a 30-year tillage cornfield in northeast China.

    PubMed

    Liu, Jie; Gao, Meixiang; Liu, Jinwen; Guo, Yuxi; Liu, Dong; Zhu, Xinyu; Wu, Donghui

    2018-01-01

    Spatial distribution is an important topic in community ecology and a key to understanding the structure and dynamics of populations and communities. However, the available information related to the spatial patterns of soil mite communities in long-term tillage agroecosystems remains insufficient. In this study, we examined the spatial patterns of soil mite communities to explain the spatial relationships between soil mite communities and soil parameters. Soil fauna were sampled three times (August, September and October 2015) at 121 locations arranged regularly within a 400 m × 400 m monitoring plot. Additionally, we estimated the physical and chemical parameters of the same sampling locations. The distribution patterns of the soil mite community and the edaphic parameters were analyzed using a range of geostatistical tools. Moran's I coefficient showed that, during each sampling period, the total abundance of the soil mite communities and the abundance of the dominant mite populations were spatially autocorrelated. The soil mite communities demonstrated clear patchy distribution patterns within the study plot. These patterns were sampling period-specific. Cross-semivariograms showed both negative and positive cross-correlations between soil mite communities and environmental factors. Mantel tests showed a significant and positive relationship between soil mite community and soil organic matter and soil pH only in August. This study demonstrated that in the cornfield, the soil mite distribution exhibited strong or moderate spatial dependence, and the mites formed patches with sizes less than one hundred meters. In addition, in this long-term tillage agroecosystem, soil factors had less influence on the observed pattern of soil mite communities. Further experiments that take into account human activity and spatial factors should be performed to study the factors that drive the spatial distribution of soil microarthropods.

  19. Spatial analysis and land use regression of VOCs and NO(2) from school-based urban air monitoring in Detroit/Dearborn, USA.

    PubMed

    Mukerjee, Shaibal; Smith, Luther A; Johnson, Mary M; Neas, Lucas M; Stallings, Casson A

    2009-08-01

    Passive ambient air sampling for nitrogen dioxide (NO(2)) and volatile organic compounds (VOCs) was conducted at 25 school and two compliance sites in Detroit and Dearborn, Michigan, USA during the summer of 2005. Geographic Information System (GIS) data were calculated at each of 116 schools. The 25 selected schools were monitored to assess and model intra-urban gradients of air pollutants to evaluate impact of traffic and urban emissions on pollutant levels. Schools were chosen to be statistically representative of urban land use variables such as distance to major roadways, traffic intensity around the schools, distance to nearest point sources, population density, and distance to nearest border crossing. Two approaches were used to investigate spatial variability. First, Kruskal-Wallis analyses and pairwise comparisons on data from the schools examined coarse spatial differences based on city section and distance from heavily trafficked roads. Secondly, spatial variation on a finer scale and as a response to multiple factors was evaluated through land use regression (LUR) models via multiple linear regression. For weeklong exposures, VOCs did not exhibit spatial variability by city section or distance from major roads; NO(2) was significantly elevated in a section dominated by traffic and industrial influence versus a residential section. Somewhat in contrast to coarse spatial analyses, LUR results revealed spatial gradients in NO(2) and selected VOCs across the area. The process used to select spatially representative sites for air sampling and the results of coarse and fine spatial variability of air pollutants provide insights that may guide future air quality studies in assessing intra-urban gradients.

  20. Impact of spatial proxies on the representation of bottom-up emission inventories: A satellite-based analysis

    NASA Astrophysics Data System (ADS)

    Geng, Guannan; Zhang, Qiang; Martin, Randall V.; Lin, Jintai; Huo, Hong; Zheng, Bo; Wang, Siwen; He, Kebin

    2017-03-01

    Spatial proxies used in bottom-up emission inventories to derive the spatial distributions of emissions are usually empirical and involve additional levels of uncertainty. Although uncertainties in current emission inventories have been discussed extensively, uncertainties resulting from improper spatial proxies have rarely been evaluated. In this work, we investigate the impact of spatial proxies on the representation of gridded emissions by comparing six gridded NOx emission datasets over China developed from the same magnitude of emissions and different spatial proxies. GEOS-Chem-modeled tropospheric NO2 vertical columns simulated from different gridded emission inventories are compared with satellite-based columns. The results show that differences between modeled and satellite-based NO2 vertical columns are sensitive to the spatial proxies used in the gridded emission inventories. The total population density is less suitable for allocating NOx emissions than nighttime light data because population density tends to allocate more emissions to rural areas. Determining the exact locations of large emission sources could significantly strengthen the correlation between modeled and observed NO2 vertical columns. Using vehicle population and an updated road network for the on-road transport sector could substantially enhance urban emissions and improve the model performance. When further applying industrial gross domestic product (IGDP) values for the industrial sector, modeled NO2 vertical columns could better capture pollution hotspots in urban areas and exhibit the best performance of the six cases compared to satellite-based NO2 vertical columns (slope = 1.01 and R2 = 0. 85). This analysis provides a framework for information from satellite observations to inform bottom-up inventory development. In the future, more effort should be devoted to the representation of spatial proxies to improve spatial patterns in bottom-up emission inventories.

  1. Current temporal asymmetry and the role of tides: Nan-Wan Bay vs. the Gulf of Elat

    NASA Astrophysics Data System (ADS)

    Ashkenazy, Y.; Fredj, E.; Gildor, H.; Gong, G. C.; Lee, H. J.; Wu, C. R.

    2016-02-01

    Nan-Wan Bay in Taiwan and the Gulf of Elat in Israel are two different coastal environments and as such are expected to have different statistical properties of their currents. While the Nan-Wan Bay is shallow, has three open boundaries, and directly connected to the open ocean, the Gulf of Elat is deep, semi-enclosed, and connected to the Red Sea via the Straits of Tiran. High temporal (less or equal one hour) and spatial (less or equal one km) surface currents have been measured continuously for more than a year in both environments using Coastal Radars (CODARs) that cover a domain of roughly 10×10 kms. These measurements show that the currents in Nan-Wan Bay are much stronger than those in the Gulf of Elat and that the mean current field in Nan-Wan Bay exhibits cyclonic circulation, which is stronger in the summer; in the Gulf of Elat the mean current field is directed to south and is stronger during the summer. We have compared the statistical properties of the CODAR current speeds in both environments and found that both exhibit large spatial and seasonal variations in the shape parameter of the Weibull distribution. However, we have found fundamental and significant differences when comparing the temporal asymmetry of the current speed (i.e., the ratio between the time during which the current speed is increasing to the total time). While the Nan-Wan Bay currents are significantly asymmetric, those of the Gulf of Elat are not significantly asymmetric. We then extracted the tidal component of the Nan-Wan Bay currents and found that it is strongly asymmetric while the asymmetry of tidally-filtered currents is much weaker. We thus conclude that the temporal asymmetry of the Nan-Wan Bay currents reported here is due to the strong tides in the region. We show that the asymmetry ratio in the Nan-Wan Bay is varied spatially and seasonally: (i) currents increase rapidly and decay slowly in the northern part of the domain and vice versa in the southern part, and that (ii) the asymmetry is stronger during summer.

  2. Assessing the competing roles of model resolution and meteorological forcing fidelity in hyperresolution simulations of snowpack and streamflow in the southern Rocky Mountains

    NASA Astrophysics Data System (ADS)

    Gochis, D. J.; Dugger, A. L.; Karsten, L. R.; Barlage, M. J.; Sampson, K. M.; Yu, W.; Pan, L.; McCreight, J. L.; Howard, K.; Busto, J.; Deems, J. S.

    2017-12-01

    Hydrometeorological processes vary over comparatively short length scales in regions of complex terrain such as the southern Rocky Mountains. Changes in temperature, precipitation, wind and solar radiation can vary significantly across elevation gradients, terrain landform and land cover conditions throughout the region. Capturing such variability in hydrologic models can necessitate the utilization of so-called `hyper-resolution' spatial meshes with effective element spacings of less than 100m. However, it is often difficult to obtain meteorological forcings of high quality in such regions at those resolutions which can result in significant uncertainty in fundamental in hydrologic model inputs. In this study we examine the comparative influences of meteorological forcing data fidelity and spatial resolution on seasonal simulations of snowpack evolution, runoff and streamflow in a set of high mountain watersheds in southern Colorado. We utilize the operational, NOAA National Water Model configuration of the community WRF-Hydro system as a baseline and compare against it, additional model scenarios with differing specifications of meteorological forcing data, with and without topographic downscaling adjustments applied, with and without experimental high resolution radar derived precipitation estimates and with WRF-Hydro configurations of progressively finer spatial resolution. The results suggest significant influence from and importance of meteorological downscaling techniques in controlling spatial distributions of meltout and runoff timing. The use of radar derived precipitation exhibits clear sensitivity on hydrologic simulation skill compared with the use of coarser resolution, background precipitation analyses. Advantages and disadvantages of the utilization of progressively higher resolution model configurations both in terms of computational requirements and model fidelity are also discussed.

  3. Possible Signaling Pathways Mediating Neuronal Calcium Sensor-1-Dependent Spatial Learning and Memory in Mice.

    PubMed

    Nakamura, Tomoe Y; Nakao, Shu; Nakajo, Yukako; Takahashi, Jun C; Wakabayashi, Shigeo; Yanamoto, Hiroji

    2017-01-01

    Intracellular Ca2+ signaling regulates diverse functions of the nervous system. Many of these neuronal functions, including learning and memory, are regulated by neuronal calcium sensor-1 (NCS-1). However, the pathways by which NCS-1 regulates these functions remain poorly understood. Consistent with the findings of previous reports, we revealed that NCS-1 deficient (Ncs1-/-) mice exhibit impaired spatial learning and memory function in the Morris water maze test, although there was little change in their exercise activity, as determined via treadmill-analysis. Expression of brain-derived neurotrophic factor (BDNF; a key regulator of memory function) and dopamine was significantly reduced in the Ncs1-/- mouse brain, without changes in the levels of glial cell-line derived neurotrophic factor or nerve growth factor. Although there were no gross structural abnormalities in the hippocampi of Ncs1-/- mice, electron microscopy analysis revealed that the density of large dense core vesicles in CA1 presynaptic neurons, which release BDNF and dopamine, was decreased. Phosphorylation of Ca2+/calmodulin-dependent protein kinase II-α (CaMKII-α, which is known to trigger long-term potentiation and increase BDNF levels, was significantly reduced in the Ncs1-/- mouse brain. Furthermore, high voltage electric potential stimulation, which increases the levels of BDNF and promotes spatial learning, significantly increased the levels of NCS-1 concomitant with phosphorylated CaMKII-α in the hippocampus; suggesting a close relationship between NCS-1 and CaMKII-α. Our findings indicate that NCS-1 may regulate spatial learning and memory function at least in part through activation of CaMKII-α signaling, which may directly or indirectly increase BDNF production.

  4. An efficient and cost-effective microchannel plate detector for slow neutron radiography

    NASA Astrophysics Data System (ADS)

    Wiggins, B. B.; Vadas, J.; Bancroft, D.; deSouza, Z. O.; Huston, J.; Hudan, S.; Baxter, D. V.; deSouza, R. T.

    2018-05-01

    A novel approach for efficiently imaging objects with slow neutrons in two dimensions is realized. Neutron sensitivity is achieved by use of a boron doped microchannel plate (MCP). The resulting electron avalanche is further amplified with a Z-stack MCP before being sensed by two orthogonally oriented wire planes. Coupling of the wire planes to delay lines efficiently encodes the position information as a time difference. To determine the position resolution, slow neutrons were used to illuminate a Cd-mask placed directly in front of the detector. Peaks in the resulting spectrum exhibited an average peak width of 329 μm FWHM, corresponding to an average intrinsic resolution of 216 μm. The center region of the detector exhibits a significantly better spatial resolution with an intrinsic resolution of <100 μm observed.

  5. Dynamic contact guidance of migrating cells

    NASA Astrophysics Data System (ADS)

    Losert, Wolfgang; Sun, Xiaoyu; Guven, Can; Driscoll, Meghan; Fourkas, John

    2014-03-01

    We investigate the effects of nanotopographical surfaces on the cell migration and cell shape dynamics of the amoeba Dictyostelium discoideum. Amoeboid motion exhibits significant contact guidance along surfaces with nanoscale ridges or grooves. We show quantitatively that nanoridges spaced 1.5 μm apart exhibit the greatest contact guidance efficiency. Using principal component analysis, we characterize the dynamics of the cell shape modulated by the coupling between the cell membrane and ridges. We show that motion parallel to the ridges is enhanced, while the turning, at the largest spatial scales, is suppressed. Since protrusion dynamics are principally governed by actin dynamics, we imaged the actin polymerization of cells on ridges. We found that actin polymerization occurs preferentially along nanoridges in a ``monorail'' like fashion. The ridges then provide us with a tool to study actin dynamics in an effectively reduced dimensional system.

  6. The effects of an inquiry-based earth science course on the spatial thinking of pre-service elementary teacher education students

    NASA Astrophysics Data System (ADS)

    Weakley, Kevin Douglas

    This study examined the effectiveness of two geography courses at improving student spatial thinking skills. Spatial thinking is an important cognitive skill in the sciences and everyday life. A taxonomy of spatial thinking was constructed by Gersmehl (2008) in geography education which included core modes assessed in this study: comparison, region, transition, analogy, pattern, and association. Two additional modes related to space over time, change and movement, were also assessed. The central research question in this study is: What are the effects of a pre-service teacher education earth science content course (Geography 1900) that is conceptually designed and inquiry-based on the spatial thinking of university students compared to the Geography 1020 course that follows a lecture format with an atlas study component? The six sub-questions to this central question were: (1) What spatial thinking modes are embedded in the Geography 1900 course based on the Gersmehl (2008) classification of modes of spatial thinking? (2) What modes of spatial thinking do pre-service elementary education students exhibit prior to instruction in Geography 1900 and 1020? (3) What changes occur in spatial thinking and spatial skills as a result of enrolling in and completing a conceptually based, inquiry course (Geography 1900) that has embedded clearly identifiable spatial tasks based on Gersmehl's classification? (4) What are the effects of Geography 1900 on the modes of spatial thinking that students apply at the completion of the course? (5) What modes of spatial thinking do students transfer from the classroom to the outdoors as they move about campus? (6) Are there differences in spatial thinking between the Geography 1900 population and the Geography 1020 comparison sample of students that received a different course treatment? The research used a mixed methods approach with both quantitative and qualitative information. Statistically significant changes were observed in the use of spatial constructs and concepts by students in each of the course treatments that were compared. Students were also observed to apply spatial modes outside the classroom that represented the spatial thinking within the new context of the university environment as they observed and described the landscape.

  7. Effect of intranasal manganese administration on neurotransmission and spatial learning in rats

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blecharz-Klin, Kamilla; Piechal, Agnieszka; Joniec-Maciejak, Ilona

    2012-11-15

    The effect of intranasal manganese chloride (MnCl{sub 2}·4H{sub 2}O) exposure on spatial learning, memory and motor activity was estimated in Morris water maze task in adult rats. Three-month-old male Wistar rats received for 2 weeks MnCl{sub 2}·4H{sub 2}O at two doses the following: 0.2 mg/kg b.w. (Mn0.2) or 0.8 mg/kg b.w. (Mn0.8) per day. Control (Con) and manganese-exposed groups were observed for behavioral performance and learning in water maze. ANOVA for repeated measurements did not show any significant differences in acquisition in the water maze between the groups. However, the results of the probe trial on day 5, exhibited spatialmore » memory deficits following manganese treatment. After completion of the behavioral experiment, the regional brain concentrations of neurotransmitters and their metabolites were determined via HPLC in selected brain regions, i.e. prefrontal cortex, hippocampus and striatum. ANOVA demonstrated significant differences in the content of monoamines and metabolites between the treatment groups compared to the controls. Negative correlations between platform crossings on the previous platform position in Southeast (SE) quadrant during the probe trial and neurotransmitter turnover suggest that impairment of spatial memory and cognitive performance after manganese (Mn) treatment is associated with modulation of the serotonergic, noradrenergic and dopaminergic neurotransmission in the brain. These findings show that intranasally applied Mn can impair spatial memory with significant changes in the tissue level and metabolism of monoamines in several brain regions. -- Highlights: ► Intranasal exposure to manganese in rats impairs spatial memory in the water maze. ► Regional changes in levels of neurotransmitters in the brain have been identified. ► Cognitive disorder correlates with modulation of 5-HT, NA and DA neurotransmission.« less

  8. Temporal and spatial variability of wind resources in the United States as derived from the Climate Forecast System Reanalysis

    Treesearch

    Lejiang Yu; Shiyuan Zhong; Xindi Bian; Warren E. Heilman

    2015-01-01

    This study examines the spatial and temporal variability of wind speed at 80m above ground (the average hub height of most modern wind turbines) in the contiguous United States using Climate Forecast System Reanalysis (CFSR) data from 1979 to 2011. The mean 80-m wind exhibits strong seasonality and large spatial variability, with higher (lower) wind speeds in the...

  9. Persistent spatial information in the frontal eye field during object-based short-term memory.

    PubMed

    Clark, Kelsey L; Noudoost, Behrad; Moore, Tirin

    2012-08-08

    Spatial attention is known to gate entry into visual short-term memory, and some evidence suggests that spatial signals may also play a role in binding features or protecting object representations during memory maintenance. To examine the persistence of spatial signals during object short-term memory, the activity of neurons in the frontal eye field (FEF) of macaque monkeys was recorded during an object-based delayed match-to-sample task. In this task, monkeys were trained to remember an object image over a brief delay, regardless of the locations of the sample or target presentation. FEF neurons exhibited visual, delay, and target period activity, including selectivity for sample location and target location. Delay period activity represented the sample location throughout the delay, despite the irrelevance of spatial information for successful task completion. Furthermore, neurons continued to encode sample position in a variant of the task in which the matching stimulus never appeared in their response field, confirming that FEF maintains sample location independent of subsequent behavioral relevance. FEF neurons also exhibited target-position-dependent anticipatory activity immediately before target onset, suggesting that monkeys predicted target position within blocks. These results show that FEF neurons maintain spatial information during short-term memory, even when that information is irrelevant for task performance.

  10. Environmental characteristics drive variation in Amazonian understorey bird assemblages

    PubMed Central

    Magnusson, William E.; Anderson, Marti J.; Schlegel, Martin; Pe’er, Guy; Henle, Klaus

    2017-01-01

    Tropical bird assemblages display patterns of high alpha and beta diversity and, as tropical birds exhibit strong habitat specificity, their spatial distributions are generally assumed to be driven primarily by environmental heterogeneity and interspecific interactions. However, spatial distributions of some Amazonian forest birds are also often restricted by large rivers and other large-scale topographic features, suggesting that dispersal limitation may also play a role in driving species’ turnover. In this study, we evaluated the effects of environmental characteristics, topographic and spatial variables on variation in local assemblage structure and diversity of birds in an old-growth forest in central Amazonia. Birds were mist-netted in 72 plots distributed systematically across a 10,000 ha reserve in each of three years. Alpha diversity remained stable through time, but species composition changed. Spatial variation in bird-assemblage structure was significantly related to environmental and topographic variables but not strongly related to spatial variables. At a broad scale, we found bird assemblages to be significantly distinct between two watersheds that are divided by a central ridgeline. We did not detect an effect of the ridgeline per se in driving these patterns, indicating that most birds are able to fly across it, and that differences in assemblage structure between watersheds may be due to unmeasured environmental variables or unique combinations of measured variables. Our study indicates that complex geography and landscape features can act together with environmental variables to drive changes in the diversity and composition of tropical bird assemblages at local scales, but highlights that we still know very little about what makes different parts of tropical forest suitable for different species. PMID:28225774

  11. Navigation Patterns and Scent Marking: Underappreciated Contributors to Hippocampal and Entorhinal Spatial Representations?

    PubMed

    Lebedev, Mikhail A; Pimashkin, Alexey; Ossadtchi, Alexei

    2018-01-01

    According to the currently prevailing theory, hippocampal formation constructs and maintains cognitive spatial maps. Most of the experimental evidence for this theory comes from the studies on navigation in laboratory rats and mice, typically male animals. While these animals exhibit a rich repertoire of behaviors associated with navigation, including locomotion, head movements, whisking, sniffing, raring and scent marking, the contribution of these behavioral patterns to the hippocampal spatially-selective activity has not been sufficiently studied. Instead, many publications have considered animal position in space as the major variable that affects the firing of hippocampal place cells and entorhinal grid cells. Here we argue that future work should focus on a more detailed examination of different behaviors exhibited during navigation to better understand the mechanism of spatial tuning in hippocampal neurons. As an inquiry in this direction, we have analyzed data from two datasets, shared online, containing recordings from rats navigating in square and round arenas. Our analyses revealed patchy navigation patterns, evident from the spatial maps of animal position, velocity and acceleration. Moreover, grid cells available in the datasets exhibited similar periodicity as the navigation parameters. These findings indicate that activity of grid cells could affect navigation parameters and/or vice versa. Additionally, we speculate that scent marks left by navigating animals could contribute to neuronal responses while rats and mice sniff their environment; the act of sniffing could modulate neuronal discharges even in virtual visual environments. Accordingly, we propose that future experiments should contain additional controls for navigation patterns, whisking, sniffing and maps composed of scent marks.

  12. The steady-state mosaic of disturbance and succession across an old-growth Central Amazon forest landscape.

    PubMed

    Chambers, Jeffrey Q; Negron-Juarez, Robinson I; Marra, Daniel Magnabosco; Di Vittorio, Alan; Tews, Joerg; Roberts, Dar; Ribeiro, Gabriel H P M; Trumbore, Susan E; Higuchi, Niro

    2013-03-05

    Old-growth forest ecosystems comprise a mosaic of patches in different successional stages, with the fraction of the landscape in any particular state relatively constant over large temporal and spatial scales. The size distribution and return frequency of disturbance events, and subsequent recovery processes, determine to a large extent the spatial scale over which this old-growth steady state develops. Here, we characterize this mosaic for a Central Amazon forest by integrating field plot data, remote sensing disturbance probability distribution functions, and individual-based simulation modeling. Results demonstrate that a steady state of patches of varying successional age occurs over a relatively large spatial scale, with important implications for detecting temporal trends on plots that sample a small fraction of the landscape. Long highly significant stochastic runs averaging 1.0 Mg biomass⋅ha(-1)⋅y(-1) were often punctuated by episodic disturbance events, resulting in a sawtooth time series of hectare-scale tree biomass. To maximize the detection of temporal trends for this Central Amazon site (e.g., driven by CO2 fertilization), plots larger than 10 ha would provide the greatest sensitivity. A model-based analysis of fractional mortality across all gap sizes demonstrated that 9.1-16.9% of tree mortality was missing from plot-based approaches, underscoring the need to combine plot and remote-sensing methods for estimating net landscape carbon balance. Old-growth tropical forests can exhibit complex large-scale structure driven by disturbance and recovery cycles, with ecosystem and community attributes of hectare-scale plots exhibiting continuous dynamic departures from a steady-state condition.

  13. Residency Patterns and Migration Dynamics of Adult Bull Sharks (Carcharhinus leucas) on the East Coast of Southern Africa

    PubMed Central

    Daly, Ryan; Smale, Malcolm J.; Cowley, Paul D.; Froneman, Pierre W.

    2014-01-01

    Bull sharks (Carcharhinus leucas) are globally distributed top predators that play an important ecological role within coastal marine communities. However, little is known about the spatial and temporal scales of their habitat use and associated ecological role. In this study, we employed passive acoustic telemetry to investigate the residency patterns and migration dynamics of 18 adult bull sharks (195–283 cm total length) tagged in southern Mozambique for a period of between 10 and 22 months. The majority of sharks (n = 16) exhibited temporally and spatially variable residency patterns interspersed with migration events. Ten individuals undertook coastal migrations that ranged between 433 and 709 km (mean  = 533 km) with eight of these sharks returning to the study site. During migration, individuals exhibited rates of movement between 2 and 59 km.d−1 (mean  = 17.58 km.d−1) and were recorded travelling annual distances of between 450 and 3760 km (mean  = 1163 km). Migration towards lower latitudes primarily took place in austral spring and winter and there was a significant negative correlation between residency and mean monthly sea temperature at the study site. This suggested that seasonal change is the primary driver behind migration events but further investigation is required to assess how foraging and reproductive activity may influence residency patterns and migration. Results from this study highlight the need for further understanding of bull shark migration dynamics and suggest that effective conservation strategies for this vulnerable species necessitate the incorporation of congruent trans-boundary policies over large spatial scales. PMID:25295972

  14. Do enhanced states exist? Boosting cognitive capacities through an action video-game.

    PubMed

    Kozhevnikov, Maria; Li, Yahui; Wong, Sabrina; Obana, Takashi; Amihai, Ido

    2018-04-01

    This research reports the existence of enhanced cognitive states in which dramatic temporary improvements in temporal and spatial aspects of attention were exhibited by participants who played (but not by those who merely observed) action video-games meeting certain criteria. Specifically, Experiments 1 and 2 demonstrate that the attentional improvements were exhibited only by participants whose skills matched the difficulty level of the video game. Experiment 2 showed that arousal (as reflected by the reduction in parasympathetic activity and increase in sympathetic activity) is a critical physiological condition for enhanced cognitive states and corresponding attentional enhancements. Experiment 3 showed that the cognitive enhancements were transient, and were no longer observed after 30 min of rest following video-gaming. Moreover, the results suggest that the enhancements were specific to tasks requiring visual-spatial focused attention, but not distribution of spatial attention as has been reported to improve significantly and durably as a result of long-term video-game playing. Overall, the results suggest that the observed enhancements cannot be simply due to the activity of video-gaming per se, but might rather represent an enhanced cognitive state resulting from specific conditions (heightened arousal in combination with active engagement and optimal challenge), resonant with what has been described in previous phenomenological literature as "flow" (Csikszentmihalyi, 1975) or "peak experiences" (Maslov, 1962). The findings provide empirical evidence for the existence of the enhanced cognitive states and suggest possibilities for consciously accessing latent resources of our brain to temporarily boost our cognitive capacities upon demand. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Pressure Fluctuations Induced by a Hypersonic Turbulent Boundary Layer

    NASA Technical Reports Server (NTRS)

    Duan, Lian; Choudhari, Meelan M.; Zhang, Chao

    2016-01-01

    Direct numerical simulations (DNS) are used to examine the pressure fluctuations generated by a spatially-developed Mach 5.86 turbulent boundary layer. The unsteady pressure field is analyzed at multiple wall-normal locations, including those at the wall, within the boundary layer (including inner layer, the log layer, and the outer layer), and in the free stream. The statistical and structural variations of pressure fluctuations as a function of wall-normal distance are highlighted. Computational predictions for mean velocity pro les and surface pressure spectrum are in good agreement with experimental measurements, providing a first ever comparison of this type at hypersonic Mach numbers. The simulation shows that the dominant frequency of boundary-layer-induced pressure fluctuations shifts to lower frequencies as the location of interest moves away from the wall. The pressure wave propagates with a speed nearly equal to the local mean velocity within the boundary layer (except in the immediate vicinity of the wall) while the propagation speed deviates from the Taylor's hypothesis in the free stream. Compared with the surface pressure fluctuations, which are primarily vortical, the acoustic pressure fluctuations in the free stream exhibit a significantly lower dominant frequency, a greater spatial extent, and a smaller bulk propagation speed. The freestream pressure structures are found to have similar Lagrangian time and spatial scales as the acoustic sources near the wall. As the Mach number increases, the freestream acoustic fluctuations exhibit increased radiation intensity, enhanced energy content at high frequencies, shallower orientation of wave fronts with respect to the flow direction, and larger propagation velocity.

  16. Characterizing and estimating noise in InSAR and InSAR time series with MODIS

    USGS Publications Warehouse

    Barnhart, William D.; Lohman, Rowena B.

    2013-01-01

    InSAR time series analysis is increasingly used to image subcentimeter displacement rates of the ground surface. The precision of InSAR observations is often affected by several noise sources, including spatially correlated noise from the turbulent atmosphere. Under ideal scenarios, InSAR time series techniques can substantially mitigate these effects; however, in practice the temporal distribution of InSAR acquisitions over much of the world exhibit seasonal biases, long temporal gaps, and insufficient acquisitions to confidently obtain the precisions desired for tectonic research. Here, we introduce a technique for constraining the magnitude of errors expected from atmospheric phase delays on the ground displacement rates inferred from an InSAR time series using independent observations of precipitable water vapor from MODIS. We implement a Monte Carlo error estimation technique based on multiple (100+) MODIS-based time series that sample date ranges close to the acquisitions times of the available SAR imagery. This stochastic approach allows evaluation of the significance of signals present in the final time series product, in particular their correlation with topography and seasonality. We find that topographically correlated noise in individual interferograms is not spatially stationary, even over short-spatial scales (<10 km). Overall, MODIS-inferred displacements and velocities exhibit errors of similar magnitude to the variability within an InSAR time series. We examine the MODIS-based confidence bounds in regions with a range of inferred displacement rates, and find we are capable of resolving velocities as low as 1.5 mm/yr with uncertainties increasing to ∼6 mm/yr in regions with higher topographic relief.

  17. Behavioural Response Thresholds in New Zealand Crab Megalopae to Ambient Underwater Sound

    PubMed Central

    Stanley, Jenni A.; Radford, Craig A.; Jeffs, Andrew G.

    2011-01-01

    A small number of studies have demonstrated that settlement stage decapod crustaceans are able to detect and exhibit swimming, settlement and metamorphosis responses to ambient underwater sound emanating from coastal reefs. However, the intensity of the acoustic cue required to initiate the settlement and metamorphosis response, and therefore the potential range over which this acoustic cue may operate, is not known. The current study determined the behavioural response thresholds of four species of New Zealand brachyuran crab megalopae by exposing them to different intensity levels of broadcast reef sound recorded from their preferred settlement habitat and from an unfavourable settlement habitat. Megalopae of the rocky-reef crab, Leptograpsus variegatus, exhibited the lowest behavioural response threshold (highest sensitivity), with a significant reduction in time to metamorphosis (TTM) when exposed to underwater reef sound with an intensity of 90 dB re 1 µPa and greater (100, 126 and 135 dB re 1 µPa). Megalopae of the mud crab, Austrohelice crassa, which settle in soft sediment habitats, exhibited no response to any of the underwater reef sound levels. All reef associated species exposed to sound levels from an unfavourable settlement habitat showed no significant change in TTM, even at intensities that were similar to their preferred reef sound for which reductions in TTM were observed. These results indicated that megalopae were able to discern and respond selectively to habitat-specific acoustic cues. The settlement and metamorphosis behavioural response thresholds to levels of underwater reef sound determined in the current study of four species of crabs, enables preliminary estimation of the spatial range at which an acoustic settlement cue may be operating, from 5 m to 40 km depending on the species. Overall, these results indicate that underwater sound is likely to play a major role in influencing the spatial patterns of settlement of coastal crab species. PMID:22163314

  18. Alcohol outlet density and violence: A geographically weighted regression approach.

    PubMed

    Cameron, Michael P; Cochrane, William; Gordon, Craig; Livingston, Michael

    2016-05-01

    We investigate the relationship between outlet density (of different types) and violence (as measured by police activity) across the North Island of New Zealand, specifically looking at whether the relationships vary spatially. We use New Zealand data at the census area unit (approximately suburb) level, on police-attended violent incidents and outlet density (by type of outlet), controlling for population density and local social deprivation. We employed geographically weighted regression to obtain both global average and locally specific estimates of the relationships between alcohol outlet density and violence. We find that bar and night club density, and licensed club density (e.g. sports clubs) have statistically significant and positive relationships with violence, with an additional bar or night club is associated with nearly 5.3 additional violent events per year, and an additional licensed club associated with 0.8 additional violent events per year. These relationships do not show significant spatial variation. In contrast, the effects of off-licence density and restaurant/café density do exhibit significant spatial variation. However, the non-varying effects of bar and night club density are larger than the locally specific effects of other outlet types. The relationships between outlet density and violence vary significantly across space for off-licences and restaurants/cafés. These results suggest that in order to minimise alcohol-related harms, such as violence, locally specific policy interventions are likely to be necessary. [Cameron MP, Cochrane W, Gordon C, Livingston M. Alcohol outlet density and violence: A geographically weighted regression approach. Drug Alcohol Rev 2016;35:280-288]. © 2015 Australasian Professional Society on Alcohol and other Drugs.

  19. Oral exposure to low-dose of nonylphenol impairs memory performance in Sprague-Dawley rats.

    PubMed

    Kawaguchi, Shinichiro; Kuwahara, Rika; Kohara, Yumi; Uchida, Yutaro; Oku, Yushi; Yamashita, Kimihiro

    2015-02-01

    Nonylphenol ethoxylate (NPE) is a non-ionic surfactant, that is degraded to short-chain NPE and 4-nonylphenol (NP) by bacteria in the environment. NP, one of the most common environmental endocrine disruptors, exhibits weak estrogen-like activity. In this study, we investigated whether oral administration of NP (at 0.5 and 5 mg/kg doses) affects spatial learning and memory, general activity, emotionality, and fear-motivated learning and memory in male and female Sprague-Dawley (SD) rats. SD rats of both sexes were evaluated using a battery of behavioral tests, including an appetite-motivated maze test (MAZE test) that was used to assess spatial learning and memory. In the MAZE test, the time required to reach the reward in male rats treated with 0.5 mg/kg NP group and female rats administered 5 mg/kg NP was significantly longer than that for control animals of the corresponding sex. In other behavioral tests, no significant differences were observed between the control group and either of the NP-treated groups of male rats. In female rats, inner and ambulation values for animals administered 0.5 mg/kg NP were significantly higher than those measured in control animals in open-field test, while the latency in the group treated with 5 mg/kg NP was significantly shorter compared to the control group in step-through passive avoidance test. This study indicates that oral administration of a low-dose of NP slightly impairs spatial learning and memory performance in male and female rats, and alters emotionality and fear-motivated learning and memory in female rats only.

  20. Spatial frequency maps of power flow in metamaterials and photonic crystals: Investigating backward-wave modes across the electromagnetic spectrum

    NASA Astrophysics Data System (ADS)

    Aghanejad, Iman; Markley, Loïc

    2017-11-01

    We present spatial frequency maps of power flow in metamaterials and photonic crystals in order to provide insights into their electromagnetic responses and further our understanding of backward power in periodic structures. Since 2001, many different structures across the electromagnetic spectrum have been presented in the literature as exhibiting an isotropic negative effective index. Although these structures all exhibit circular or spherical equifrequency contours that resemble those of left-handed media, here we show through k -space diagrams that the distribution of power in the spatial frequency domain can vary considerably across these structures. In particular, we show that backward power arises from high-order right-handed harmonics in photonic crystals, magnetodielectric crystals, and across the layers of coupled-plasmonic-waveguide metamaterials, while arising from left-handed harmonic pairs in split-ring resonator and wire composites, plasmonic crystals, and along the layers of coupled-plasmonic-waveguide metamaterials. We also show that the fishnet structure exhibits the same left-handed harmonic pairs as the latter group. These observations allow us to categorize different metamaterials according to their spatial spectral source of backward power and identify the mechanism behind negative refraction at a given interface. Finally, we discuss how k -space maps of power flow can be used to explain the high or low transmittance of power into different metamaterial or photonic crystal structures.

  1. Modular and hierarchical structure of social contact networks

    NASA Astrophysics Data System (ADS)

    Ge, Yuanzheng; Song, Zhichao; Qiu, Xiaogang; Song, Hongbin; Wang, Yong

    2013-10-01

    Social contact networks exhibit overlapping qualities of communities, hierarchical structure and spatial-correlated nature. We propose a mixing pattern of modular and growing hierarchical structures to reconstruct social contact networks by using an individual’s geospatial distribution information in the real world. The hierarchical structure of social contact networks is defined based on the spatial distance between individuals, and edges among individuals are added in turn from the modular layer to the highest layer. It is a gradual process to construct the hierarchical structure: from the basic modular model up to the global network. The proposed model not only shows hierarchically increasing degree distribution and large clustering coefficients in communities, but also exhibits spatial clustering features of individual distributions. As an evaluation of the method, we reconstruct a hierarchical contact network based on the investigation data of a university. Transmission experiments of influenza H1N1 are carried out on the generated social contact networks, and results show that the constructed network is efficient to reproduce the dynamic process of an outbreak and evaluate interventions. The reproduced spread process exhibits that the spatial clustering of infection is accordant with the clustering of network topology. Moreover, the effect of individual topological character on the spread of influenza is analyzed, and the experiment results indicate that the spread is limited by individual daily contact patterns and local clustering topology rather than individual degree.

  2. Memory retrieval along the proximodistal axis of CA1.

    PubMed

    Nakazawa, Yuki; Pevzner, Aleksandr; Tanaka, Kazumasa Z; Wiltgen, Brian J

    2016-09-01

    The proximal and distal segments of CA1 are thought to perform distinct computations. Neurons in proximal CA1 are reciprocally connected with the medial entorhinal cortex (MEC) and exhibit precise spatial firing. In contrast, cells in distal CA1 communicate with the lateral entorhinal cortex (LEC), exhibit more diffuse spatial firing and are affected by the presence of objects in the environment. To determine if these segments make unique contributions to memory retrieval, we examined cellular activity along the proximodistal axis of CA1 using transgenic reporter mice. Neurons tagged during context learning in proximal CA1 were more likely to be reactivated during testing than those in distal CA1. This was true following context fear conditioning and after exposure to a novel environment. Reactivation was also higher in brain regions connected to proximal CA1 (MEC, distal CA3) than those connected to the distal segment (LEC, proximal CA3). To examine contributions to memory retrieval, we performed neurotoxic lesions of proximal or distal CA1 after training. Lesions of the proximal segment significantly impaired memory retrieval while damage to distal CA1 had no effect. These data suggest that context memories are retrieved by a hippocampal microcircuit that involves the proximal but not distal segment of CA1. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. Explaining local-scale species distributions: relative contributions of spatial autocorrelation and landscape heterogeneity for an avian assemblage

    USGS Publications Warehouse

    Mattsson, Brady J.; Zipkin, Elise F.; Gardner, Beth; Blank, Peter J.; Sauer, John R.; Royle, J. Andrew

    2013-01-01

    Understanding interactions between mobile species distributions and landcover characteristics remains an outstanding challenge in ecology. Multiple factors could explain species distributions including endogenous evolutionary traits leading to conspecific clustering and endogenous habitat features that support life history requirements. Birds are a useful taxon for examining hypotheses about the relative importance of these factors among species in a community. We developed a hierarchical Bayes approach to model the relationships between bird species occupancy and local landcover variables accounting for spatial autocorrelation, species similarities, and partial observability. We fit alternative occupancy models to detections of 90 bird species observed during repeat visits to 316 point-counts forming a 400-m grid throughout the Patuxent Wildlife Research Refuge in Maryland, USA. Models with landcover variables performed significantly better than our autologistic and null models, supporting the hypothesis that local landcover heterogeneity is important as an exogenous driver for species distributions. Conspecific clustering alone was a comparatively poor descriptor of local community composition, but there was evidence for spatial autocorrelation in all species. Considerable uncertainty remains whether landcover combined with spatial autocorrelation is most parsimonious for describing bird species distributions at a local scale. Spatial structuring may be weaker at intermediate scales within which dispersal is less frequent, information flows are localized, and landcover types become spatially diversified and therefore exhibit little aggregation. Examining such hypotheses across species assemblages contributes to our understanding of community-level associations with conspecifics and landscape composition.

  4. Phase Synchronization and Desynchronization of Structural Response Induced by Turbulent and External Sound

    NASA Technical Reports Server (NTRS)

    Maestrello, Lucio

    2002-01-01

    Acoustic and turbulent boundary layer flow loadings over a flexible structure are used to study the spatial-temporal dynamics of the response of the structure. The stability of the spatial synchronization and desynchronization by an active external force is investigated with an array of coupled transducers on the structure. In the synchronous state, the structural phase is locked, which leads to the formation of spatial patterns while the amplitude peaks exhibit chaotic behaviors. Large amplitude, spatially symmetric loading is superimposed on broadband, but in the desynchronized state, the spectrum broadens and the phase space is lost. The resulting pattern bears a striking resemblance to phase turbulence. The transition is achieved by using a low power external actuator to trigger broadband behaviors from the knowledge of the external acoustic load inducing synchronization. The changes are made favorably and efficiently to alter the frequency distribution of power, not the total power level. Before synchronization effects are seen, the panel response to the turbulent boundary layer loading is discontinuously spatio-temporally correlated. The stability develops from different competing wavelengths; the spatial scale is significantly shorter than when forced with the superimposed external sound. When the external sound level decreases and the synchronized phases are lost, changes in the character of the spectra can be linked to the occurrence of spatial phase transition. These changes can develop broadband response. Synchronized responses of fuselage structure panels have been observed in subsonic and supersonic aircraft; results from two flights tests are discussed.

  5. Explaining local-scale species distributions: relative contributions of spatial autocorrelation and landscape heterogeneity for an avian assemblage.

    PubMed

    Mattsson, Brady J; Zipkin, Elise F; Gardner, Beth; Blank, Peter J; Sauer, John R; Royle, J Andrew

    2013-01-01

    Understanding interactions between mobile species distributions and landcover characteristics remains an outstanding challenge in ecology. Multiple factors could explain species distributions including endogenous evolutionary traits leading to conspecific clustering and endogenous habitat features that support life history requirements. Birds are a useful taxon for examining hypotheses about the relative importance of these factors among species in a community. We developed a hierarchical Bayes approach to model the relationships between bird species occupancy and local landcover variables accounting for spatial autocorrelation, species similarities, and partial observability. We fit alternative occupancy models to detections of 90 bird species observed during repeat visits to 316 point-counts forming a 400-m grid throughout the Patuxent Wildlife Research Refuge in Maryland, USA. Models with landcover variables performed significantly better than our autologistic and null models, supporting the hypothesis that local landcover heterogeneity is important as an exogenous driver for species distributions. Conspecific clustering alone was a comparatively poor descriptor of local community composition, but there was evidence for spatial autocorrelation in all species. Considerable uncertainty remains whether landcover combined with spatial autocorrelation is most parsimonious for describing bird species distributions at a local scale. Spatial structuring may be weaker at intermediate scales within which dispersal is less frequent, information flows are localized, and landcover types become spatially diversified and therefore exhibit little aggregation. Examining such hypotheses across species assemblages contributes to our understanding of community-level associations with conspecifics and landscape composition.

  6. Explaining Local-Scale Species Distributions: Relative Contributions of Spatial Autocorrelation and Landscape Heterogeneity for an Avian Assemblage

    PubMed Central

    Mattsson, Brady J.; Zipkin, Elise F.; Gardner, Beth; Blank, Peter J.; Sauer, John R.; Royle, J. Andrew

    2013-01-01

    Understanding interactions between mobile species distributions and landcover characteristics remains an outstanding challenge in ecology. Multiple factors could explain species distributions including endogenous evolutionary traits leading to conspecific clustering and endogenous habitat features that support life history requirements. Birds are a useful taxon for examining hypotheses about the relative importance of these factors among species in a community. We developed a hierarchical Bayes approach to model the relationships between bird species occupancy and local landcover variables accounting for spatial autocorrelation, species similarities, and partial observability. We fit alternative occupancy models to detections of 90 bird species observed during repeat visits to 316 point-counts forming a 400-m grid throughout the Patuxent Wildlife Research Refuge in Maryland, USA. Models with landcover variables performed significantly better than our autologistic and null models, supporting the hypothesis that local landcover heterogeneity is important as an exogenous driver for species distributions. Conspecific clustering alone was a comparatively poor descriptor of local community composition, but there was evidence for spatial autocorrelation in all species. Considerable uncertainty remains whether landcover combined with spatial autocorrelation is most parsimonious for describing bird species distributions at a local scale. Spatial structuring may be weaker at intermediate scales within which dispersal is less frequent, information flows are localized, and landcover types become spatially diversified and therefore exhibit little aggregation. Examining such hypotheses across species assemblages contributes to our understanding of community-level associations with conspecifics and landscape composition. PMID:23393564

  7. The antioxidant activity of Beta vulgaris leaf extract in improving scopolamine-induced spatial memory disorders in rats.

    PubMed

    Hajihosseini, Shadieh; Setorki, Mahbubeh; Hooshmandi, Zahra

    2017-01-01

    Medicinal plants have attracted global attention due to their safety as well as their considerable antioxidant content that helps to prevent or ameliorate various disorders including memory impairments. This study was conducted to investigate the effect of beet root ( Beta vulgaris ) leaf extract on scopolamine-induced spatial memory impairments in male Wistar rats. Male Wistar rats were randomly divided into 5 groups (n=10): Control (C), scopolamine 1 mg/kg/day (S), scopolamine+50 mg/kg B. vulgaris leaf extract (S+B 50), scopolamine+100 mg/kg B. vulgaris leaf extract (S+B 100) and scopolamine+200 mg/kg B. vulgaris leaf extract (S+B 200). Morris water maze task was used to assess spatial memory. Serum antioxidant capacity and malondialdehyde (MDA) level were also measured. Group S spent significantly less time in the target quadrant compared to the control group, and the administration of B. vulgaris leaf extract (100 and 200 mg/kg) significantly increased this time (p<0.05). Scopolamine decreased serum antioxidant capacity and increased serum MDA level yet insignificantly. B. vulgaris extract (200 mg/kg) significantly increased the antioxidant capacity and decreased serum MDA level in scopolamine-treated rats (p<0.05). Our results suggested that B. vulgaris leaf extract could ameliorate the memory impairments and exhibited protective effects against scopolamine-induced oxidation. Further investigation is needed to isolate specific antioxidant compounds from B. vulgaris leaf extract with protective effect against brain and memory impairments.

  8. Tidal and atmospheric forcing of the upper ocean in the Gulf of California. I - Sea surface temperature variability

    NASA Technical Reports Server (NTRS)

    Paden, Cynthia A.; Winant, Clinton D.; Abbott, Mark R.

    1991-01-01

    SST variability in the northern Gulf of California is examined on the basis of findings of two years of satellite infrared imagery (1984-1986). Empirical orthogonal functions of the temporal and spatial SST variance for 20 monthly mean images show that the dominant SST patterns are generated by spatially varying tidal mixing in the presence of seasonal heating and cooling. Atmospheric forcing of the northern gulf appears to occur over large spatial scales. Area-averaged SSTs for the Guaymas Basin, island region, and northern basin exhibit significant fluctuations which are highly correlated. These fluctuations in SST correspond to similar fluctuations in the air temperature which are related to synoptic weather events over the gulf. A regression analysis of the SST relative to the fortnightly tidal range shows that tidal mixing occurs over the sills in the island region as well as on the shallow northern shelf. Mixing over the sills occurs as a result of large breaking internal waves of internal hydraulic jumps which mix over water in the upper 300-500 m.

  9. The Importance of Visual Experience, Gender, and Emotion in the Assessment of an Assistive Tactile Mouse.

    PubMed

    Brayda, Luca; Campus, Claudio; Memeo, Mariacarla; Lucagrossi, Laura

    2015-01-01

    Tactile maps are efficient tools to improve spatial understanding and mobility skills of visually impaired people. Their limited adaptability can be compensated with haptic devices which display graphical information, but their assessment is frequently limited to performance-based metrics only which can hide potential spatial abilities in O&M protocols. We assess a low-tech tactile mouse able to deliver three-dimensional content considering how performance, mental workload, behavior, and anxiety status vary with task difficulty and gender in congenitally blind, late blind, and sighted subjects. Results show that task difficulty coherently modulates the efficiency and difficulty to build mental maps, regardless of visual experience. Although exhibiting attitudes that were similar and gender-independent, the females had lower performance and higher cognitive load, especially when congenitally blind. All groups showed a significant decrease in anxiety after using the device. Tactile graphics with our device seems therefore to be applicable with different visual experiences, with no negative emotional consequences of mentally demanding spatial tasks. Going beyond performance-based assessment, our methodology can help with better targeting technological solutions in orientation and mobility protocols.

  10. Spatial and temporal variation of H and O isotopic compositions of the Xijiang River system, Southwest China.

    PubMed

    Han, Guilin; Lv, Pin; Tang, Yang; Song, Zhaoliang

    2018-05-01

    Ratios of stable isotopes of hydrogen and oxygen ( 2 H/ 1 H and 18 O/ 16 O) in river waters were measured to investigate the hydrological pathway of the Xijiang River, Southwest China. The δ 2 H and δ 18 O values of river waters exhibit significant spatial and temporal variations and the isotopic compositions vary with elevation, temperature and precipitation of the recharge area. Spatially, δ 18 O values of river waters from high mountain areas are lower than those from the lower reaches of the Xijiang River due to lower temperature and higher elevation for the recharge area. However, both 2 H and 18 O are enriched differently in river waters from the middle reaches during the high flow season, depending on the season and degree of anthropogenic disturbances (e.g. water impoundments). In contrast, deuterium excess (d-excess) values of waters from the middle reaches are substantially lower than those from the upper and lower reaches, suggesting that river waters may be resided in the reservoir and evaporation increases in the middle reaches of the Xijiang River.

  11. Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome.

    PubMed

    O'Connor, James P B; Rose, Chris J; Waterton, John C; Carano, Richard A D; Parker, Geoff J M; Jackson, Alan

    2015-01-15

    Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance and may influence response to therapy. Imaging can quantify the spatial variation in architecture and function of individual tumors through quantifying basic biophysical parameters such as CT density or MRI signal relaxation rate; through measurements of blood flow, hypoxia, metabolism, cell death, and other phenotypic features; and through mapping the spatial distribution of biochemical pathways and cell signaling networks using PET, MRI, and other emerging molecular imaging techniques. These methods can establish whether one tumor is more or less heterogeneous than another and can identify subregions with differing biology. In this article, we review the image analysis methods currently used to quantify spatial heterogeneity within tumors. We discuss how analysis of intratumor heterogeneity can provide benefit over more simple biomarkers such as tumor size and average function. We consider how imaging methods can be integrated with genomic and pathology data, instead of being developed in isolation. Finally, we identify the challenges that must be overcome before measurements of intratumoral heterogeneity can be used routinely to guide patient care. ©2014 American Association for Cancer Research.

  12. Spatial vegetation patterns and neighborhood competition among woody plants in an East African savanna.

    PubMed

    Dohn, Justin; Augustine, David J; Hanan, Niall P; Ratnam, Jayashree; Sankaran, Mahesh

    2017-02-01

    The majority of research on savanna vegetation dynamics has focused on the coexistence of woody and herbaceous vegetation. Interactions among woody plants in savannas are relatively poorly understood. We present data from a 10-yr longitudinal study of spatially explicit growth patterns of woody vegetation in an East African savanna following exclusion of large herbivores and in the absence of fire. We examined plant spatial patterns and quantified the degree of competition among woody individuals. Woody plants in this semiarid savanna exhibit strongly clumped spatial distributions at scales of 1-5 m. However, analysis of woody plant growth rates relative to their conspecific and heterospecific neighbors revealed evidence for strong competitive interactions at neighborhood scales of up to 5 m for most woody plant species. Thus, woody plants were aggregated in clumps despite significantly decreased growth rates in close proximity to neighbors, indicating that the spatial distribution of woody plants in this region depends on dispersal and establishment processes rather than on competitive, density-dependent mortality. However, our documentation of suppressive effects of woody plants on neighbors also suggests a potentially important role for tree-tree competition in controlling vegetation structure and indicates that the balanced-competition hypothesis may contribute to well-known patterns in maximum tree cover across rainfall gradients in Africa. © 2016 by the Ecological Society of America.

  13. Spatial working memory in heavy cannabis users: a functional magnetic resonance imaging study.

    PubMed

    Kanayama, Gen; Rogowska, Jadwiga; Pope, Harrison G; Gruber, Staci A; Yurgelun-Todd, Deborah A

    2004-11-01

    Many neuropsychological studies have documented deficits in working memory among recent heavy cannabis users. However, little is known about the effects of cannabis on brain activity. We assessed brain function among recent heavy cannabis users while they performed a working memory task. Functional magnetic resonance imaging was used to examine brain activity in 12 long-term heavy cannabis users, 6-36 h after last use, and in 10 control subjects while they performed a spatial working memory task. Regional brain activation was analyzed and compared using statistical parametric mapping techniques. Compared with controls, cannabis users exhibited increased activation of brain regions typically used for spatial working memory tasks (such as prefrontal cortex and anterior cingulate). Users also recruited additional regions not typically used for spatial working memory (such as regions in the basal ganglia). These findings remained essentially unchanged when re-analyzed using subjects' ages as a covariate. Brain activation showed little or no significant correlation with subjects' years of education, verbal IQ, lifetime episodes of cannabis use, or urinary cannabinoid levels at the time of scanning. Recent cannabis users displayed greater and more widespread brain activation than normal subjects when attempting to perform a spatial working memory task. This observation suggests that recent cannabis users may experience subtle neurophysiological deficits, and that they compensate for these deficits by "working harder"-calling upon additional brain regions to meet the demands of the task.

  14. Impact of Satellite Viewing-Swath Width on Global and Regional Aerosol Optical Thickness Statistics and Trends

    NASA Technical Reports Server (NTRS)

    Colarco, P. R.; Kahn, R. A.; Remer, L. A.; Levy, R. C.

    2014-01-01

    We use the Moderate Resolution Imaging Spectroradiometer (MODIS) satellite aerosol optical thickness (AOT) product to assess the impact of reduced swath width on global and regional AOT statistics and trends. Alongtrack and across-track sampling strategies are employed, in which the full MODIS data set is sub-sampled with various narrow-swath (approximately 400-800 km) and single pixel width (approximately 10 km) configurations. Although view-angle artifacts in the MODIS AOT retrieval confound direct comparisons between averages derived from different sub-samples, careful analysis shows that with many portions of the Earth essentially unobserved, spatial sampling introduces uncertainty in the derived seasonal-regional mean AOT. These AOT spatial sampling artifacts comprise up to 60%of the full-swath AOT value under moderate aerosol loading, and can be as large as 0.1 in some regions under high aerosol loading. Compared to full-swath observations, narrower swath and single pixel width sampling exhibits a reduced ability to detect AOT trends with statistical significance. On the other hand, estimates of the global, annual mean AOT do not vary significantly from the full-swath values as spatial sampling is reduced. Aggregation of the MODIS data at coarse grid scales (10 deg) shows consistency in the aerosol trends across sampling strategies, with increased statistical confidence, but quantitative errors in the derived trends are found even for the full-swath data when compared to high spatial resolution (0.5 deg) aggregations. Using results of a model-derived aerosol reanalysis, we find consistency in our conclusions about a seasonal-regional spatial sampling artifact in AOT Furthermore, the model shows that reduced spatial sampling can amount to uncertainty in computed shortwave top-ofatmosphere aerosol radiative forcing of 2-3 W m(sup-2). These artifacts are lower bounds, as possibly other unconsidered sampling strategies would perform less well. These results suggest that future aerosol satellite missions having significantly less than full-swath viewing are unlikely to sample the true AOT distribution well enough to obtain the statistics needed to reduce uncertainty in aerosol direct forcing of climate.

  15. Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus.

    PubMed

    Upton, Maureen L; Guilak, Farshid; Laursen, Tod A; Setton, Lori A

    2006-06-01

    The knee meniscus exhibits significant spatial variations in biochemical composition and cell morphology that reflect distinct phenotypes of cells located in the radial inner and outer regions. Associated with these cell phenotypes is a spatially heterogeneous microstructure and mechanical environment with the innermost regions experiencing higher fluid pressures and lower tensile strains than the outer regions. It is presently unknown, however, how meniscus tissue mechanics correlate with the local micromechanical environment of cells. In this study, theoretical models were developed to study mechanics of inner and outer meniscus cells with varying geometries. The results for an applied biaxial strain predict significant regional differences in the cellular mechanical environment with evidence of tensile strains along the collagen fiber direction of approximately 0.07 for the rounded inner cells, as compared to levels of 0.02-0.04 for the elongated outer meniscus cells. The results demonstrate an important mechanical role of extracellular matrix anisotropy and cell morphology in regulating the region-specific micromechanics of meniscus cells, that may further play a role in modulating cellular responses to mechanical stimuli.

  16. Drainage-system development in consecutive melt seasons at a polythermal, Arctic glacier, evaluated by flow-recession analysis and linear-reservoir simulation.

    PubMed

    Hodgkins, Richard; Cooper, Richard; Tranter, Martyn; Wadham, Jemma

    2013-07-26

    [1] The drainage systems of polythermal glaciers play an important role in high-latitude hydrology, and are determinants of ice flow rate. Flow-recession analysis and linear-reservoir simulation of runoff time series are here used to evaluate seasonal and inter-annual variability in the drainage system of the polythermal Finsterwalderbreen, Svalbard, in 1999 and 2000. Linear-flow recessions are pervasive, with mean coefficients of a fast reservoir varying from 16 (1999) to 41 h (2000), and mean coefficients of an intermittent, slow reservoir varying from 54 (1999) to 114 h (2000). Drainage-system efficiency is greater overall in the first of the two seasons, the simplest explanation of which is more rapid depletion of the snow cover. Reservoir coefficients generally decline during each season (at 0.22 h d -1 in 1999 and 0.52 h d -1 in 2000), denoting an increase in drainage efficiency. However, coefficients do not exhibit a consistent relationship with discharge. Finsterwalderbreen therefore appears to behave as an intermediate case between temperate glaciers and other polythermal glaciers with smaller proportions of temperate ice. Linear-reservoir runoff simulations exhibit limited sensitivity to a relatively wide range of reservoir coefficients, although the use of fixed coefficients in a spatially lumped model can generate significant subseasonal error. At Finsterwalderbreen, an ice-marginal channel with the characteristics of a fast reservoir, and a subglacial upwelling with the characteristics of a slow reservoir, both route meltwater to the terminus. This suggests that drainage-system components of significantly contrasting efficiencies can coexist spatially and temporally at polythermal glaciers.

  17. Spatial structure of morphological and neutral genetic variation in Brook Trout

    USGS Publications Warehouse

    Kazyak, David C.; Hilderbrand, Robert H.; Keller, Stephen R.; Colaw, Mark C.; Holloway, Amanda E.; Morgan, Raymond P.; King, Timothy L.

    2015-01-01

    Brook Trout Salvelinus fontinalis exhibit exceptional levels of life history variation, remarkable genetic variability, and fine-scale population structure. In many cases, neighboring populations may be highly differentiated from one another to an extent that is comparable with species-level distinctions in other taxa. Although genetic samples have been collected from hundreds of populations and tens of thousands of individuals, little is known about whether differentiation at neutral markers reflects phenotypic differences among Brook Trout populations. We compared differentiation in morphology and neutral molecular markers among populations from four geographically proximate locations (all within 24 km) to examine how genetic diversity covaries with morphology. We found significant differences among and/or within streams for all three morphological axes examined and identified the source stream of many individuals based on morphology (52.3% classification efficiency). Although molecular and morphological differentiation among streams ranged considerably (mean pairwise FST: 0.023–0.264; pairwise PST: 0.000–0.339), the two measures were not significantly correlated. While in some cases morphological characters appear to have diverged to a greater extent than expected by neutral genetic drift, many traits were conserved to a greater extent than were neutral genetic markers. Thus, while Brook Trout exhibit fine-scale spatial patterns in both morphology and neutral genetic diversity, these types of biological variabilities are being structured by different ecological and evolutionary processes. The relative influences of genetic drift versus selection and phenotypic plasticity in shaping morphology appear to vary among populations occupying nearby streams.

  18. Public health expenditure and spatial interactions in a decentralized national health system.

    PubMed

    Costa-Font, Joan; Pons-Novell, Jordi

    2007-03-01

    One of the limitations of cross-country health expenditure analysis refers to the fact that the financing, the internal organization and political restraints of health care decision-making are country-specific and heterogeneous. Yet, a way through is to examine the influence of such effects in those countries that have undertaken decentralization processes. In such a setting, it is possible to examine potential expenditure spillovers across the geography of a country as well as the influence of the political ideology of regional incumbents and institutional factors on public health expenditure. This paper examines the determinants of public health expenditure within Spanish region-states (Autonomous Communities, ACs), most of them subject to similar financing structures although exhibiting significant heterogeneity as a result of the increasing decentralization, region-specific political factors along with different use of health care inputs, economic dimension and spatial interactions. Copyright (c) 2006 John Wiley & Sons, Ltd.

  19. SINGLE NEURON ACTIVITY AND THETA MODULATION IN POSTRHINAL CORTEX DURING VISUAL OBJECT DISCRIMINATION

    PubMed Central

    Furtak, Sharon C.; Ahmed, Omar J.; Burwell, Rebecca D.

    2012-01-01

    Postrhinal cortex, the rodent homolog of the primate parahippocampal cortex, processes spatial and contextual information. Our hypothesis of postrhinal function is that it serves to encode context, in part, by forming representations that link objects to places. We recorded postrhinal neuronal activity and local field potentials (LFPs) in rats trained on a two-choice, visual discrimination task. As predicted, a large proportion of postrhinal neurons signaled object-location conjunctions. In addition, postrhinal LFPs exhibited strong oscillatory rhythms in the theta band, and many postrhinal neurons were phase locked to theta. Although correlated with running speed, theta power was lower than predicted by speed alone immediately before and after choice. However, theta power was significantly increased following incorrect decisions, suggesting a role in signaling error. These findings provide evidence that postrhinal cortex encodes representations that link objects to places and suggest that postrhinal theta modulation extends to cognitive as well as spatial functions. PMID:23217745

  20. Differential phytosociological interactions involving male and female atriplex bonnevillensis

    USGS Publications Warehouse

    Sinclair, J.; Emlen, J.M.; Rinella, M.; Snelgrove, J.; Freeman, D.C.

    2009-01-01

    Wind-pollinated dioecious plants often exhibit spatial segregation of the sexes. This partial niche separation has most often been explored using abiotic niche axes. However, if the sexes are truly separated in space, then they are apt to encounter different plant species that may heavily affect growth and reproduction. Also, to the extent that their niches differ, the sexes may respond differently to the same co-occurring species. Here we examine interspecific interactions that influence male and female reproductive potential in Atriplex bonnevillensis. Using Emlen's interaction assessment, a technique which assesses species interactions based on cover classes, we show that Salsola species compete significantly with females but not males, while Halogeton glomeratus competes with males but not females. The effect of competition only became apparent when we corrected for site-specific fertility. These results imply that differential competition must be considered when studying dioecious plants that display spatial segregation of the sexes.

  1. Confidence mediates the sex difference in mental rotation performance.

    PubMed

    Estes, Zachary; Felker, Sydney

    2012-06-01

    On tasks that require the mental rotation of 3-dimensional figures, males typically exhibit higher accuracy than females. Using the most common measure of mental rotation (i.e., the Mental Rotations Test), we investigated whether individual variability in confidence mediates this sex difference in mental rotation performance. In each of four experiments, the sex difference was reliably elicited and eliminated by controlling or manipulating participants' confidence. Specifically, confidence predicted performance within and between sexes (Experiment 1), rendering confidence irrelevant to the task reliably eliminated the sex difference in performance (Experiments 2 and 3), and manipulating confidence significantly affected performance (Experiment 4). Thus, confidence mediates the sex difference in mental rotation performance and hence the sex difference appears to be a difference of performance rather than ability. Results are discussed in relation to other potential mediators and mechanisms, such as gender roles, sex stereotypes, spatial experience, rotation strategies, working memory, and spatial attention.

  2. Bisphenol-A exposures and behavioural aberrations: median and linear spline and meta-regression analyses of 12 toxicity studies in rodents.

    PubMed

    Peluso, Marco E M; Munnia, Armelle; Ceppi, Marcello

    2014-11-05

    Exposures to bisphenol-A, a weak estrogenic chemical, largely used for the production of plastic containers, can affect the rodent behaviour. Thus, we examined the relationships between bisphenol-A and the anxiety-like behaviour, spatial skills, and aggressiveness, in 12 toxicity studies of rodent offspring from females orally exposed to bisphenol-A, while pregnant and/or lactating, by median and linear splines analyses. Subsequently, the meta-regression analysis was applied to quantify the behavioural changes. U-shaped, inverted U-shaped and J-shaped dose-response curves were found to describe the relationships between bisphenol-A with the behavioural outcomes. The occurrence of anxiogenic-like effects and spatial skill changes displayed U-shaped and inverted U-shaped curves, respectively, providing examples of effects that are observed at low-doses. Conversely, a J-dose-response relationship was observed for aggressiveness. When the proportion of rodents expressing certain traits or the time that they employed to manifest an attitude was analysed, the meta-regression indicated that a borderline significant increment of anxiogenic-like effects was present at low-doses regardless of sexes (β)=-0.8%, 95% C.I. -1.7/0.1, P=0.076, at ≤120 μg bisphenol-A. Whereas, only bisphenol-A-males exhibited a significant inhibition of spatial skills (β)=0.7%, 95% C.I. 0.2/1.2, P=0.004, at ≤100 μg/day. A significant increment of aggressiveness was observed in both the sexes (β)=67.9,C.I. 3.4, 172.5, P=0.038, at >4.0 μg. Then, bisphenol-A treatments significantly abrogated spatial learning and ability in males (P<0.001 vs. females). Overall, our study showed that developmental exposures to low-doses of bisphenol-A, e.g. ≤120 μg/day, were associated to behavioural aberrations in offspring. Copyright © 2014. Published by Elsevier Ireland Ltd.

  3. Time evolution of atmospheric parameters and their influence on sea level pressure over the head Bay of Bengal

    NASA Astrophysics Data System (ADS)

    Patra, Anindita; Bhaskaran, Prasad K.; Jose, Felix

    2018-06-01

    A zonal dipole in the observed trends of wind speed and significant wave height over the Head Bay of Bengal region was recently reported in the literature attributed due to the variations in sea level pressure (SLP). The SLP in turn is governed by prevailing atmospheric conditions such as local temperature, humidity, rainfall, atmospheric pressure, wind field distribution, formation of tropical cyclones, etc. The present study attempts to investigate the inter-annual variability of atmospheric parameters and its role on the observed zonal dipole trend in sea level pressure, surface wind speed and significant wave height. It reports on the aspects related to linear trend as well as its spatial variability for several atmospheric parameters: air temperature, geopotential height, omega (vertical velocity), and zonal wind, over the head Bay of Bengal, by analyzing National Centers for Environmental Prediction (NCEP) Reanalysis 2 dataset covering a period of 38 years (1979-2016). Significant warming from sea level to 200 mb pressure level and thereafter cooling above has been noticed during all the seasons. Warming within the troposphere exhibits spatial difference between eastern and western side of the domain. This led to fall in lower tropospheric geopotential height and its east-west variability, exhibiting a zonal dipole pattern across the Head Bay. In the upper troposphere, uplift in geopotential height was found as a result of cooling in higher levels (10-100 mb). Variability in omega also substantiated the observed variations in geopotential height. The study also finds weakening in the upper level westerlies and easterlies. Interestingly, a linear trend in lower tropospheric u-wind component also reveals an east-west dipole pattern over the study region. Further, the study corroborates the reported dipole in trends of sea level pressure, wind speed and significant wave height by evaluating the influence of atmospheric variability on these parameters.

  4. Local Hotspots In The Gulf Of Maine: Spatial Overlap Between Dynamic Aggregations Of Primary Productivity And Fish Abundance

    NASA Astrophysics Data System (ADS)

    Ribera, M.

    2016-02-01

    Identification of biological hotspots may be a necessary step toward ecosystem-based management goals, as these often signal underlying processes that aggregate or stimulate resources in a particular location. However, previously used metrics to locate these hotspots are not easily adapted to local marine datasets, in part due to the high spatial and temporal variability of phytoplankton populations. While most fish species in temperate regions are well adapted to the seasonal variability of phytoplankton abundance, it is the variability beyond this predictable pattern (i.e. anomalies) that may heavily impact the abundance and spatial distribution of organisms higher up the food chain. The objective of this study was to identify local-scale biological hotspots in a region in the western side of the Gulf of Maine using remote sensing chlorophyll-a data (from MERIS sensor), and to study the spatial overlap between these hotspots and high concentrations of fish abundance (derived from VTR dataset). For this reason, we defined a new hotspot metric that identified as a hotspot any area that consistently exhibited high-magnitude anomalies through time, a sign of highly dynamic communities. We improved on previous indices by minimizing the effect that different means and variances across space may have on the results, a situation that often occurs when comparing coastal and offshore systems. Results show a significant spatial correlation between pelagic fish abundance and aggregations of primary productivity. Spatial correlations were also significant between benthic fish abundance and primary productivity hotspots, but only during spring months. We argue that this new hotspot index compliments existing global measures as it helps managers understand the dynamic characteristics of a complex marine system. It also provides a unique metric that is easily compared across space and between different trophic levels, which may facilitate future ecosystem-wide studies.

  5. Local Hotspots In The Gulf Of Maine: Spatial Overlap Between Dynamic Aggregations Of Primary Productivity And Fish Abundance

    NASA Astrophysics Data System (ADS)

    Ribera, M.

    2016-12-01

    Identification of biological hotspots may be a necessary step toward ecosystem-based management goals, as these often signal underlying processes that aggregate or stimulate resources in a particular location. However, previously used metrics to locate these hotspots are not easily adapted to local marine datasets, in part due to the high spatial and temporal variability of phytoplankton populations. While most fish species in temperate regions are well adapted to the seasonal variability of phytoplankton abundance, it is the variability beyond this predictable pattern (i.e. anomalies) that may heavily impact the abundance and spatial distribution of organisms higher up the food chain. The objective of this study was to identify local-scale biological hotspots in a region in the western side of the Gulf of Maine using remote sensing chlorophyll-a data (from MERIS sensor), and to study the spatial overlap between these hotspots and high concentrations of fish abundance (derived from VTR dataset). For this reason, we defined a new hotspot metric that identified as a hotspot any area that consistently exhibited high-magnitude anomalies through time, a sign of highly dynamic communities. We improved on previous indices by minimizing the effect that different means and variances across space may have on the results, a situation that often occurs when comparing coastal and offshore systems. Results show a significant spatial correlation between pelagic fish abundance and aggregations of primary productivity. Spatial correlations were also significant between benthic fish abundance and primary productivity hotspots, but only during spring months. We argue that this new hotspot index compliments existing global measures as it helps managers understand the dynamic characteristics of a complex marine system. It also provides a unique metric that is easily compared across space and between different trophic levels, which may facilitate future ecosystem-wide studies.

  6. Brief report: visual-spatial deficit in a 16-year-old girl with maternally derived duplication of proximal 15q.

    PubMed

    Cohen, David; Martel, Claire; Wilson, Anna; Déchambre, Nicole; Amy, Céline; Duverger, Ludovic; Guile, Jean-Marc; Pipiras, Eva; Benzacken, Brigitte; Cavé, Hélène; Cohen, Laurent; Héron, Delphine; Plaza, Monique

    2007-09-01

    Duplications of chromosome 15 may be one of the most common single genetic causes of autism spectrum disorders (ASD), aside from fragile X. Most of the cases are associated with maternally derived interstitial duplication involving 15q11-13. This case report describes a female proband with a maternally derived interstitial duplication of proximal 15q. She did not exhibit any symptoms of ASD apart from some developmental delay. By adolescence, she showed mild dysmorphism, a discrepant profile on the Wechsler Intelligence Scale for Children (Verbal IQ = 87; Performance IQ = 65) and a major deficit in visual-spatial abilities affecting fine motor skills, mathematical reasoning, visual memory and some global reading tasks. This is one of the first reports of a child with a maternal duplication who exhibits a visual-spatial deficit without ASD.

  7. Relationship between sugarcane rust severity and soil properties in louisiana.

    PubMed

    Johnson, Richard M; Grisham, Michael P; Richard, Edward P

    2007-06-01

    ABSTRACT The extent of spatial and temporal variability of sugarcane rust (Puccinia melanocephala) infestation was related to variation in soil properties in five commercial fields of sugarcane (interspecific hybrids of Saccharum spp., cv. LCP 85-384) in southern Louisiana. Sugarcane fields were grid-soil sampled at several intensities and rust ratings were collected at each point over 6 to 7 weeks. Soil properties exhibited significant variability (coefficients of variation = 9 to 70.1%) and were spatially correlated in 39 of 40 cases with a range of spatial correlation varying from 39 to 201 m. Rust ratings were spatially correlated in 32 of 33 cases, with a range varying from 29 to 241 m. Rust ratings were correlated with several soil properties, most notably soil phosphorus (r = 0.40 to 0.81) and soil sulfur (r = 0.36 to 0.68). Multiple linear regression analysis resulted in coefficients of determination that ranged from 0.22 to 0.73, and discriminant analysis further improved the overall predictive ability of rust models. Finally, contour plots of soil properties and rust levels clearly suggested a link between these two parameters. These combined data suggest that sugarcane growers that apply fertilizer in excess of plant requirements will increase the incidence and severity of rust infestations in their fields.

  8. Spatio-temporal variation in click production rates of beaked whales: Implications for passive acoustic density estimation.

    PubMed

    Warren, Victoria E; Marques, Tiago A; Harris, Danielle; Thomas, Len; Tyack, Peter L; Aguilar de Soto, Natacha; Hickmott, Leigh S; Johnson, Mark P

    2017-03-01

    Passive acoustic monitoring has become an increasingly prevalent tool for estimating density of marine mammals, such as beaked whales, which vocalize often but are difficult to survey visually. Counts of acoustic cues (e.g., vocalizations), when corrected for detection probability, can be translated into animal density estimates by applying an individual cue production rate multiplier. It is essential to understand variation in these rates to avoid biased estimates. The most direct way to measure cue production rate is with animal-mounted acoustic recorders. This study utilized data from sound recording tags deployed on Blainville's (Mesoplodon densirostris, 19 deployments) and Cuvier's (Ziphius cavirostris, 16 deployments) beaked whales, in two locations per species, to explore spatial and temporal variation in click production rates. No spatial or temporal variation was detected within the average click production rate of Blainville's beaked whales when calculated over dive cycles (including silent periods between dives); however, spatial variation was detected when averaged only over vocal periods. Cuvier's beaked whales exhibited significant spatial and temporal variation in click production rates within vocal periods and when silent periods were included. This evidence of variation emphasizes the need to utilize appropriate cue production rates when estimating density from passive acoustic data.

  9. Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations

    NASA Astrophysics Data System (ADS)

    Hosny, Neveen A.; Lee, David A.; Knight, Martin M.

    2012-01-01

    Fluorescence lifetime imaging microscopy offers a non-invasive method for quantifying local oxygen concentrations. However, existing methods are either invasive, require custom-made systems, or show limited spatial resolution. Therefore, these methods are unsuitable for investigation of pericellular oxygen concentrations. This study describes an adaptation of commercially available equipment which has been optimized for quantitative extracellular oxygen detection with high lifetime accuracy and spatial resolution while avoiding systematic photon pile-up. The oxygen sensitive fluorescent dye, tris(2,2'-bipyridyl)ruthenium(II) chloride hexahydrate [Ru(bipy)3]2+, was excited using a two-photon excitation laser. Lifetime was measured using a Becker & Hickl time-correlated single photon counting, which will be referred to as a TCSPC card. [Ru(bipy)3]2+ characterization studies quantified the influences of temperature, pH, cellular culture media and oxygen on the fluorescence lifetime measurements. This provided a precisely calibrated and accurate system for quantification of pericellular oxygen concentration based on measured lifetimes. Using this technique, quantification of oxygen concentrations around isolated viable chondrocytes, seeded in three-dimensional agarose gel, revealed a subpopulation of cells that exhibited significant spatial oxygen gradients such that oxygen concentration reduced with increasing proximity to the cell. This technique provides a powerful tool for quantifying spatial oxygen gradients within three-dimensional cellular models.

  10. Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations.

    PubMed

    Hosny, Neveen A; Lee, David A; Knight, Martin M

    2012-01-01

    Fluorescence lifetime imaging microscopy offers a non-invasive method for quantifying local oxygen concentrations. However, existing methods are either invasive, require custom-made systems, or show limited spatial resolution. Therefore, these methods are unsuitable for investigation of pericellular oxygen concentrations. This study describes an adaptation of commercially available equipment which has been optimized for quantitative extracellular oxygen detection with high lifetime accuracy and spatial resolution while avoiding systematic photon pile-up. The oxygen sensitive fluorescent dye, tris(2,2'-bipyridyl)ruthenium(II) chloride hexahydrate [Ru(bipy)(3)](2+), was excited using a two-photon excitation laser. Lifetime was measured using a Becker & Hickl time-correlated single photon counting, which will be referred to as a TCSPC card. [Ru(bipy)(3)](2+) characterization studies quantified the influences of temperature, pH, cellular culture media and oxygen on the fluorescence lifetime measurements. This provided a precisely calibrated and accurate system for quantification of pericellular oxygen concentration based on measured lifetimes. Using this technique, quantification of oxygen concentrations around isolated viable chondrocytes, seeded in three-dimensional agarose gel, revealed a subpopulation of cells that exhibited significant spatial oxygen gradients such that oxygen concentration reduced with increasing proximity to the cell. This technique provides a powerful tool for quantifying spatial oxygen gradients within three-dimensional cellular models.

  11. Metacommunity ecology meets biogeography: effects of geographical region, spatial dynamics and environmental filtering on community structure in aquatic organisms.

    PubMed

    Heino, Jani; Soininen, Janne; Alahuhta, Janne; Lappalainen, Jyrki; Virtanen, Risto

    2017-01-01

    Metacommunity patterns and underlying processes in aquatic organisms have typically been studied within a drainage basin. We examined variation in the composition of six freshwater organismal groups across various drainage basins in Finland. We first modelled spatial structures within each drainage basin using Moran eigenvector maps. Second, we partitioned variation in community structure among three groups of predictors using constrained ordination: (1) local environmental variables, (2) spatial variables, and (3) dummy variable drainage basin identity. Third, we examined turnover and nestedness components of multiple-site beta diversity, and tested the best fit patterns of our datasets using the "elements of metacommunity structure" analysis. Our results showed that basin identity and local environmental variables were significant predictors of community structure, whereas within-basin spatial effects were typically negligible. In half of the organismal groups (diatoms, bryophytes, zooplankton), basin identity was a slightly better predictor of community structure than local environmental variables, whereas the opposite was true for the remaining three organismal groups (insects, macrophytes, fish). Both pure basin and local environmental fractions were, however, significant after accounting for the effects of the other predictor variable sets. All organismal groups exhibited high levels of beta diversity, which was mostly attributable to the turnover component. Our results showed consistent Clementsian-type metacommunity structures, suggesting that subgroups of species responded similarly to environmental factors or drainage basin limits. We conclude that aquatic communities across large scales are mostly determined by environmental and basin effects, which leads to high beta diversity and prevalence of Clementsian community types.

  12. GH improves spatial memory and reverses certain anabolic androgenic steroid-induced effects in intact rats.

    PubMed

    Grönbladh, Alfhild; Johansson, Jenny; Nöstl, Anatole; Nyberg, Fred; Hallberg, Mathias

    2013-01-01

    GH has previously been shown to promote cognitive functions in GH-deficient rodents. In this study we report the effects of GH on learning and memory in intact rats pretreated with the anabolic androgenic steroid nandrolone. Male Wistar rats received nandrolone decanoate (15 mg/kg) or peanut oil every third day for 3 weeks and were subsequently treated with recombinant human GH (1.0 IU/kg) or saline for 10 consecutive days. During the GH/saline treatment spatial learning and memory were tested in the Morris water maze (MWM). Also, plasma levels of IGF1 were assessed and the gene expression of the GH receptors (Ghr), Igf1 and Igf2, in hippocampus and frontal cortex was analyzed. The results demonstrated a significant positive effect of GH on memory functions and increased gene expression of Igf1 in the hippocampus was found in the animals treated with GH. In addition, GH was demonstrated to increase the body weight gain and was able to attenuate the reduced body weight seen in nandrolone-treated animals. In general, the rats treated with nandrolone alone did not exhibit any pronounced alteration in memory compared with controls in the MWM, and in many cases GH did not induce any alteration. Regarding target zone crossings, considered to be associated with spatial memory, the difference between GH- and steroid-treated animals was significant and administration of GH improved this parameter in the latter group. In conclusion, GH improves spatial memory in intact rats and can reverse certain effects induced by anabolic androgenic steroid.

  13. Errors on interrupter tasks presented during spatial and verbal working memory performance are linearly linked to large-scale functional network connectivity in high temporal resolution resting state fMRI.

    PubMed

    Magnuson, Matthew Evan; Thompson, Garth John; Schwarb, Hillary; Pan, Wen-Ju; McKinley, Andy; Schumacher, Eric H; Keilholz, Shella Dawn

    2015-12-01

    The brain is organized into networks composed of spatially separated anatomical regions exhibiting coherent functional activity over time. Two of these networks (the default mode network, DMN, and the task positive network, TPN) have been implicated in the performance of a number of cognitive tasks. To directly examine the stable relationship between network connectivity and behavioral performance, high temporal resolution functional magnetic resonance imaging (fMRI) data were collected during the resting state, and behavioral data were collected from 15 subjects on different days, exploring verbal working memory, spatial working memory, and fluid intelligence. Sustained attention performance was also evaluated in a task interleaved between resting state scans. Functional connectivity within and between the DMN and TPN was related to performance on these tasks. Decreased TPN resting state connectivity was found to significantly correlate with fewer errors on an interrupter task presented during a spatial working memory paradigm and decreased DMN/TPN anti-correlation was significantly correlated with fewer errors on an interrupter task presented during a verbal working memory paradigm. A trend for increased DMN resting state connectivity to correlate to measures of fluid intelligence was also observed. These results provide additional evidence of the relationship between resting state networks and behavioral performance, and show that such results can be observed with high temporal resolution fMRI. Because cognitive scores and functional connectivity were collected on nonconsecutive days, these results highlight the stability of functional connectivity/cognitive performance coupling.

  14. Spatial Acuity and Prey Detection in Weakly Electric Fish

    PubMed Central

    Babineau, David; Lewis, John E; Longtin, André

    2007-01-01

    It is well-known that weakly electric fish can exhibit extreme temporal acuity at the behavioral level, discriminating time intervals in the submicrosecond range. However, relatively little is known about the spatial acuity of the electrosense. Here we use a recently developed model of the electric field generated by Apteronotus leptorhynchus to study spatial acuity and small signal extraction. We show that the quality of sensory information available on the lateral body surface is highest for objects close to the fish's midbody, suggesting that spatial acuity should be highest at this location. Overall, however, this information is relatively blurry and the electrosense exhibits relatively poor acuity. Despite this apparent limitation, weakly electric fish are able to extract the minute signals generated by small prey, even in the presence of large background signals. In fact, we show that the fish's poor spatial acuity may actually enhance prey detection under some conditions. This occurs because the electric image produced by a spatially dense background is relatively “blurred” or spatially uniform. Hence, the small spatially localized prey signal “pops out” when fish motion is simulated. This shows explicitly how the back-and-forth swimming, characteristic of these fish, can be used to generate motion cues that, as in other animals, assist in the extraction of sensory information when signal-to-noise ratios are low. Our study also reveals the importance of the structure of complex electrosensory backgrounds. Whereas large-object spacing is favorable for discriminating the individual elements of a scene, small spacing can increase the fish's ability to resolve a single target object against this background. PMID:17335346

  15. Inter-specific territoriality in a Canis hybrid zone: spatial segregation between wolves, coyotes, and hybrids.

    PubMed

    Benson, John F; Patterson, Brent R

    2013-12-01

    Gray wolves (Canis lupus) and coyotes (Canis latrans) generally exhibit intraspecific territoriality manifesting in spatial segregation between adjacent packs. However, previous studies have found a high degree of interspecific spatial overlap between sympatric wolves and coyotes. Eastern wolves (Canis lycaon) are the most common wolf in and around Algonquin Provincial Park (APP), Ontario, Canada and hybridize with sympatric gray wolves and coyotes. We hypothesized that all Canis types (wolves, coyotes, and hybrids) exhibit a high degree of spatial segregation due to greater genetic, morphologic, and ecological similarities between wolves and coyotes in this hybrid system compared with western North American ecosystems. We used global positioning system telemetry and probabilistic measures of spatial overlap to investigate spatial segregation between adjacent Canis packs. Our hypothesis was supported as: (1) the probability of locating wolves, coyotes, and hybrids within home ranges ([Formula: see text] = 0.05) or core areas ([Formula: see text] < 0.01) of adjacent packs was low; and (2) the amount of shared space use was negligible. Spatial segregation did not vary substantially in relation to genotypes of adjacent packs or local environmental conditions (i.e., harvest regulations or road densities). We provide the first telemetry-based demonstration of spatial segregation between wolves and coyotes, highlighting the novel relationships between Canis types in the Ontario hybrid zone relative to areas where wolves and coyotes are reproductively isolated. Territoriality among Canis may increase the likelihood of eastern wolves joining coyote and hybrid packs, facilitate hybridization, and could play a role in limiting expansion of the genetically distinct APP eastern wolf population.

  16. Effect of Action Video Games on the Spatial Distribution of Visuospatial Attention

    ERIC Educational Resources Information Center

    Green, C. Shawn; Bavelier, Daphne

    2006-01-01

    The authors investigated the effect of action gaming on the spatial distribution of attention. The authors used the flanker compatibility effect to separately assess center and peripheral attentional resources in gamers versus nongamers. Gamers exhibited an enhancement in attentional resources compared with nongamers, not only in the periphery but…

  17. The PKC-β selective inhibitor, Enzastaurin, impairs memory in middle-aged rats.

    PubMed

    Willeman, Mari N; Mennenga, Sarah E; Siniard, Ashley L; Corneveaux, Jason J; De Both, Matt; Hewitt, Lauren T; Tsang, Candy W S; Caselli, Jason; Braden, B Blair; Bimonte-Nelson, Heather A; Huentelman, Matthew J

    2018-01-01

    Enzastaurin is a Protein Kinase C-β selective inhibitor that was developed to treat cancers. Protein Kinase C-β is an important enzyme for a variety of neuronal functions; in particular, previous rodent studies have reported deficits in spatial and fear-conditioned learning and memory with lower levels of Protein Kinase C-β. Due to Enzastaurin's mechanism of action, the present study investigated the consequences of Enzastaurin exposure on learning and memory in 12-month-old Fischer-344 male rats. Rats were treated daily with subcutaneous injections of either vehicle or Enzastaurin, and behaviorally tested using the spatial reference memory Morris Water Maze. Rats treated with Enzastaurin exhibited decreased overnight retention and poorer performance on the latter testing day, indicating a mild, but significant, memory impairment. There were no differences during the probe trial indicating that all animals were able to spatially localize the platform to the proper quadrant by the end of testing. RNA isolated from the hippocampus was analyzed using Next Generation Sequencing (Illumina). No statistically significant transcriptional differences were noted. Our findings suggest that acute Enzastaurin treatment can impair hippocampal-based learning and memory performance, with no effects on transcription in the hippocampus. We propose that care should be taken in future clinical trials that utilize Protein Kinase C-ß inhibitors, to monitor for possible cognitive effects, future research should examine if these effects are fully reversible.

  18. Preliminary assessment of cognitive impairments in canine idiopathic epilepsy.

    PubMed

    Winter, Joshua; Packer, Rowena Mary Anne; Volk, Holger Andreas

    2018-06-02

    In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies. The aim of our study was to assess CI in dogs with IE using two tests of cognitive dysfunction designed for use in a clinical setting. Dogs with IE (n=17) were compared against controls (n=18) in their performance in two tasks; a spatial working memory task and a problem-solving task. In addition, owners completed the Canine Cognitive Dysfunction Rating (CCDR) scale for their dog. The groups did not differ statistically with respect to age and breed. Dogs with IE performed significantly worse than controls on the spatial working memory task (P = 0.016), but not on the problem solving task (P=0.683). CCDR scores were significantly higher in the IE group (P=0.016); however, no dogs reach the recommended threshold score for CCD diagnosis. Our preliminary data suggest that dogs with IE exhibit impairments in a spatial working memory task. Further research is required to explore the effect of IE on other cognitive abilities in dogs with a larger sample, characterising the age of onset, nature and progression of any impairments and the impact of anti-epileptic drugs. © British Veterinary Association (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  19. Perinatal exposure to genistein, a soy phytoestrogen, improves spatial learning and memory but impairs passive avoidance learning and memory in offspring.

    PubMed

    Kohara, Yumi; Kuwahara, Rika; Kawaguchi, Shinichiro; Jojima, Takeshi; Yamashita, Kimihiro

    2014-05-10

    This study investigated the effects of perinatal genistein (GEN) exposure on the central nervous system of rat offspring. Pregnant dams orally received GEN (1 or 10 mg/kg/day) or vehicle (1 ml/kg/day) from gestation day 10 to postnatal day 14. In order to assess the effects of GEN on rat offspring, we used a battery of behavioral tests, including the open-field, elevated plus-maze, MAZE and step-through passive avoidance tests. MAZE test is an appetite-motivation test, and we used this mainly for assessing spatial learning and memory. In the MAZE test, GEN groups exhibited shorter latency from start to goal than the vehicle-treated group in both sexes. On the other hand, performances in the step-through passive avoidance test were non-monotonically inhibited by GEN in both sexes, and a significant difference was observed in low dose of the GEN-treated group compared to the vehicle-treated group in female rats. Furthermore, we found that perinatal exposure to GEN did not significantly alter locomotor activity or emotionality as assessed by the open-field and elevated-plus maze tests. These results suggest that perinatal exposure to GEN improved spatial learning and memory of rat offspring, but impaired their passive avoidance learning and memory. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Neural Correlates of Object-Associated Choice Behavior in the Perirhinal Cortex of Rats

    PubMed Central

    Ahn, Jae-Rong

    2015-01-01

    The perirhinal cortex (PRC) is reportedly important for object recognition memory, with supporting physiological evidence obtained largely from primate studies. Whether neurons in the rodent PRC also exhibit similar physiological correlates of object recognition, however, remains to be determined. We recorded single units from the PRC in a PRC-dependent, object-cued spatial choice task in which, when cued by an object image, the rat chose the associated spatial target from two identical discs appearing on a touchscreen monitor. The firing rates of PRC neurons were significantly modulated by critical events in the task, such as object sampling and choice response. Neuronal firing in the PRC was correlated primarily with the conjunctive relationships between an object and its associated choice response, although some neurons also responded to the choice response alone. However, we rarely observed a PRC neuron that represented a specific object exclusively regardless of spatial response in rats, although the neurons were influenced by the perceptual ambiguity of the object at the population level. Some PRC neurons fired maximally after a choice response, and this post-choice feedback signal significantly enhanced the neuronal specificity for the choice response in the subsequent trial. Our findings suggest that neurons in the rat PRC may not participate exclusively in object recognition memory but that their activity may be more dynamically modulated in conjunction with other variables, such as choice response and its outcomes. PMID:25632144

  1. Tunable plasmon lensing in graphene-based structure exhibiting negative refraction.

    PubMed

    Zhong, Shifeng; Lu, Yanxin; Li, Chao; Xu, Haixia; Shi, Fenghua; Chen, Yihang

    2017-02-02

    We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provide the hyperbolic dispersion relations of the graphene plasmon, giving rise to the all-angle plasmonic negative refraction. Plasmon lensing induced from the negative refraction is observed. We show that the ultracompact graphene-based system can produce sub-diffraction-limited images with the resolution significant smaller than the wavelength of the incident terahertz wave. Moreover, by adjusting the Fermi energy of the graphene, the imaging performance of the proposed system can remain almost invariant for different frequencies. Our results may find applications in diverse fields such as subwavelength spatial light manipulation, biological imaging, and so forth.

  2. Tunable plasmon lensing in graphene-based structure exhibiting negative refraction

    PubMed Central

    Zhong, Shifeng; Lu, Yanxin; Li, Chao; Xu, Haixia; Shi, Fenghua; Chen, Yihang

    2017-01-01

    We propose a novel method to achieve tunable plasmon focusing in graphene/photonic-crystal hybrid structure exhibiting all-angle negative refraction at terahertz frequencies. A two-dimensional photonic crystal composed of a square lattice of dielectric rods is constructed on the substrate of a graphene sheet to provide the hyperbolic dispersion relations of the graphene plasmon, giving rise to the all-angle plasmonic negative refraction. Plasmon lensing induced from the negative refraction is observed. We show that the ultracompact graphene-based system can produce sub-diffraction-limited images with the resolution significant smaller than the wavelength of the incident terahertz wave. Moreover, by adjusting the Fermi energy of the graphene, the imaging performance of the proposed system can remain almost invariant for different frequencies. Our results may find applications in diverse fields such as subwavelength spatial light manipulation, biological imaging, and so forth. PMID:28150750

  3. Homogenized electromechanical properties of crystalline and ceramic relaxor ferroelectric 0.58Pb(Mg1/3Nb2/3)O3 0.42PbTiO3

    NASA Astrophysics Data System (ADS)

    Jayachandran, K. P.; Guedes, J. M.; Rodrigues, H. C.

    2007-10-01

    A modelling framework that incorporates the peculiarities of microstructural features, such as the spatial correlation of crystallographic orientations and morphological texture in piezoelectrics, is established. The mathematical homogenization theory of a piezoelectric medium is implemented using the finite element method by solving the coupled equilibrium electrical and mechanical fields. The dependence of the domain orientation on the macroscopic electromechanical properties of crystalline as well as polycrystalline ceramic relaxor ferroelectric 0.58Pb(Mg1/3Nb2/3)O3-0.42PbTiO3 (PMN-42% PT) is studied based on this model. The material shows large anisotropy in the piezoelectric coefficient ejK in its crystalline form. The homogenized electromechanical moduli of polycrystalline ceramic also exhibit significantly anisotropic behaviours. An optimum texture at which the piezoceramic exhibits its maximum longitudinal piezoelectric response is identified.

  4. Effects of spatial resolution and landscape structure on land cover characterization

    NASA Astrophysics Data System (ADS)

    Yang, Wenli

    This dissertation addressed problems in scaling, problems that are among the main challenges in remote sensing. The principal objective of the research was to investigate the effects of changing spatial scale on the representation of land cover. A second objective was to determine the relationship between such effects, characteristics of landscape structure and scaling procedures. Four research issues related to spatial scaling were examined. They included: (1) the upscaling of Normalized Difference Vegetation Index (NDVI); (2) the effects of spatial scale on indices of landscape structure; (3) the representation of land cover databases at different spatial scales; and (4) the relationships between landscape indices and land cover area estimations. The overall bias resulting from non-linearity of NDVI in relation to spatial resolution is generally insignificant as compared to other factors such as influences of aerosols and water vapor. The bias is, however, related to land surface characteristics. Significant errors may be introduced in heterogeneous areas where different land cover types exhibit strong spectral contrast. Spatially upscaled SPOT and TM NDVIs have information content comparable with the AVHRR-derived NDVI. Indices of landscape structure and spatial resolution are generally related, but the exact forms of the relationships are subject to changes in other factors including the basic patch unit constituting a landscape and the proportional area of foreground land cover under consideration. The extent of agreement between spatially aggregated coarse resolution land cover datasets and full resolution datasets changes with the properties of the original datasets, including the pixel size and class definition. There are close relationships between landscape structure and class areas estimated from spatially aggregated land cover databases. The relationships, however, do not permit extension from one area to another. Inversion calibration across different geographic/ecological areas is, therefore, not feasible. Different rules govern the land cover area changes across resolutions when different upscaling methods are used. Special attention should be given to comparison between land cover maps derived using different methods.

  5. Spatial short-term memory in children with nonverbal learning disabilities: impairment in encoding spatial configuration.

    PubMed

    Narimoto, Tadamasa; Matsuura, Naomi; Takezawa, Tomohiro; Mitsuhashi, Yoshinori; Hiratani, Michio

    2013-01-01

    The authors investigated whether impaired spatial short-term memory exhibited by children with nonverbal learning disabilities is due to a problem in the encoding process. Children with or without nonverbal learning disabilities performed a simple spatial test that required them to remember 3, 5, or 7 spatial items presented simultaneously in random positions (i.e., spatial configuration) and to decide if a target item was changed or all items including the target were in the same position. The results showed that, even when the spatial positions in the encoding and probe phases were similar, the mean proportion correct of children with nonverbal learning disabilities was 0.58 while that of children without nonverbal learning disabilities was 0.84. The authors argue with the results that children with nonverbal learning disabilities have difficulty encoding relational information between spatial items, and that this difficulty is responsible for their impaired spatial short-term memory.

  6. IS THERE CONVERGENCE ACROSS COUNTRIES? A SPATIAL APPROACH

    PubMed Central

    Berry, Heather; Guillen, Mauro F.; Hendi, Arun S.

    2014-01-01

    We analyze convergence across countries over the last half century as a result of globalizing forces. Drawing on theories of modernization, dependency, the world-system, political trade blocs, and the world-society, we consider economic, demographic, knowledge, financial, and political dimensions of convergence. Using a new methodology, we calculate the minimum volume ellipsoid encompassing different groupings of countries, finding that during the 1960–2009 period, countries have not evolved significantly closer or similar to one another, although groups of countries based on their core-periphery status or membership in trade blocs exhibit increasing internal convergence and divergence between one another. PMID:25580035

  7. The possible modifications of the Hisse model for pure LANDSAT agricultural data

    NASA Technical Reports Server (NTRS)

    Peters, C.

    1982-01-01

    An idea, due to A. Feiveson, is presented for relaxing the assumption of class conditional independence of LANDSAT spectral measurements within the same patch (field). Theoretical arguments are given which show that any significant refinement of the model beyond Feiveson's proposal will not allow the reduction, essential to HISSE, of the pure data to patch summary statistics. A slight alteration of the new model is shown to be a reasonable approximation to the model which describes pure data elements from the same patch as jointly Guassian with a covariance function which exhibits exponential decay with respect to spatial separation.

  8. Spectral linewidth of spin-current nano-oscillators driven by nonlocal spin injection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Demidov, V. E., E-mail: demidov@uni-muenster.de; Divinskiy, B.; Urazhdin, S.

    2015-11-16

    We study experimentally the auto-oscillation characteristics of magnetic nano-oscillators driven by pure spin currents generated by nonlocal spin injection. By combining micro-focus Brillouin light scattering spectroscopy with electronic microwave spectroscopy, we are able to simultaneously perform both the spatial and the high-resolution spectral analyses of auto-oscillations induced by spin current. We find that the devices exhibit a highly coherent dynamics with the spectral linewidth of a few megahertz at room temperature. This narrow linewidth can be achieved over a wide range of operational frequencies, demonstrating a significant potential of nonlocal oscillators for applications.

  9. The possible modifications of the HISSE model for pure LANDSAT agricultural data

    NASA Technical Reports Server (NTRS)

    Peters, C.

    1981-01-01

    A method for relaxing the assumption of class conditional independence of LANDSAT spectral measurements within the same patch (field) is discussed. Theoretical arguments are given which show that any significant refinement of the model beyond this proposal will not allow the reduction, essential to HISSE, of the pure data to patch summary statistics. A slight alteration of the new model is shown to be a reasonable approximation to the model which describes pure data elements from the same patch as jointly Gaussian with a covariance function which exhibits exponential decay with respect to spatial separation.

  10. Formalized description and construction of semantic dictionary of graphic-text spatial relationship

    NASA Astrophysics Data System (ADS)

    Sun, Yizhong; Xue, Xiaolei; Zhao, Xiaoqin

    2008-10-01

    Graphic and text are two major elements in exhibiting of the results of urban planning and land administration. In combination, they convey the complex relationship resulting from spatial analysis and decision-making. Accurately interpreting and representing these relationships are important steps towards an intelligent GIS for urban planning. This paper employs concept-hierarchy-tree to formalize graphic-text relationships through a framework of spatial object lexicon, spatial relationship lexicon, restriction lexicon, applied pattern base, and word segmentation rule base. The methodology is further verified and shown effective on several urban planning archives.

  11. Beneficial effects of exercise and its molecular mechanisms on depression in rats

    PubMed Central

    Zheng, Hang; Liu, Yanyou; Li, Wei; Yang, Bo; Chen, Dengbang; Wang, Xiaojia; Jiang, Zhou; Wang, Hongxing; Wang, Zhengrong; Cornelisson, G.; Halberg, F.

    2008-01-01

    Exercise showed the beneficial effects on mental health in depressed sufferers, whereas, its underlying mechanisms remained unresolved. This study utilized the chronic unpredictable stress (CNS) animal model of depression to evaluate the effects of exercise on depressive behaviors and spatial performance in rats. Furthermore, we tested the hypothesis that the capacity of exercise to reverse the harmful effects of CNS was relative to the hypothalamo–pituitary–adrenal (HPA) system and brain-derived neurotrophic factor (BDNF) in the hippocampus. Animal groups were exposed to CNS for 4 weeks with and without access to voluntary wheel running. Stressed rats consumed significantly less of a 1% sucrose solution during CNS and exhibited a significant decrease in open field behavior. On the other hand, they showed impaired spatial performance in Morris water maze test 2 weeks after the end of CNS. Further, CNS significantly decreased hippocampal BDNF mRNA levels. However, voluntary exercise improved or even reversed these harmful behavioral effects in stressed rats. Furthermore, exercise counteracted a decrease in hippocampal BDNF mRNA caused by CNS. In addition, we also found that CMS alone increased circulating corticosterone (CORT) significantly and decreased hippocampal glucocorticoid receptor (GR) mRNA. At the same time, exercise alone increased CORT moderately and did not affect hippocampal GR mRNA levels. While, when both CNS and exercise were combined, exercise reduced the increase of CORT and the decrease of GR caused by CMS. The results demonstrated that: (1) exercise reversed the harmful effects of CNS on mood and spatial performance in rats and (2) the behavioral changes induced by exercise and/or CNS might be associated with hippocampal BDNF levels, and in addition, the HPA system might play different roles in the two different processes. PMID:16290283

  12. Phase synchrony reveals organization in human atrial fibrillation

    PubMed Central

    Vidmar, David; Narayan, Sanjiv M.

    2015-01-01

    It remains unclear if human atrial fibrillation (AF) is spatially nonhierarchical or exhibits a hierarchy of organization sustained by sources. We utilize activation times obtained at discrete locations during AF to compute the phase synchrony between tissue regions, to examine underlying spatial dynamics throughout both atria. We construct a binary synchronization network and show that this network can accurately define regions of coherence in coarse-grained in silico data. Specifically, domains controlled by spiral waves exhibit regions of high phase synchrony. We then apply this analysis to clinical data from patients experiencing cardiac arrhythmias using multielectrode catheters to simultaneously record from a majority of both atria. We show that pharmaceutical intervention with ibutilide organizes activation by increasing the size of the synchronized domain in AF and quantify the increase in temporal organization when arrhythmia changes from fibrillation to tachycardia. Finally, in recordings from 24 patients in AF we show that the level of synchrony is spatially broad with some patients showing large spatially contiguous regions of synchronization, while in others synchrony is localized to small pockets. Using computer simulations, we show that this distribution is inconsistent with distributions obtained from simulations that mimic multiwavelet reentry but is consistent with mechanisms in which one or more spatially conserved spiral waves is surrounded by tissue in which activation is disorganized. PMID:26475585

  13. Analysis of temporal decay of diffuse broadband sound fields in enclosures by decomposition in powers of an absorption parameter

    NASA Astrophysics Data System (ADS)

    Bliss, Donald; Franzoni, Linda; Rouse, Jerry; Manning, Ben

    2005-09-01

    An analysis method for time-dependent broadband diffuse sound fields in enclosures is described. Beginning with a formulation utilizing time-dependent broadband intensity boundary sources, the strength of these wall sources is expanded in a series in powers of an absorption parameter, thereby giving a separate boundary integral problem for each power. The temporal behavior is characterized by a Taylor expansion in the delay time for a source to influence an evaluation point. The lowest-order problem has a uniform interior field proportional to the reciprocal of the absorption parameter, as expected, and exhibits relatively slow exponential decay. The next-order problem gives a mean-square pressure distribution that is independent of the absorption parameter and is primarily responsible for the spatial variation of the reverberant field. This problem, which is driven by input sources and the lowest-order reverberant field, depends on source location and the spatial distribution of absorption. Additional problems proceed at integer powers of the absorption parameter, but are essentially higher-order corrections to the spatial variation. Temporal behavior is expressed in terms of an eigenvalue problem, with boundary source strength distributions expressed as eigenmodes. Solutions exhibit rapid short-time spatial redistribution followed by long-time decay of a predominant spatial mode.

  14. Spatial synchrony in cisco recruitment

    USGS Publications Warehouse

    Myers, Jared T.; Yule, Daniel L.; Jones, Michael L.; Ahrenstorff, Tyler D.; Hrabik, Thomas R.; Claramunt, Randall M.; Ebener, Mark P.; Berglund, Eric K.

    2015-01-01

    We examined the spatial scale of recruitment variability for disparate cisco (Coregonus artedi) populations in the Great Lakes (n = 8) and Minnesota inland lakes (n = 4). We found that the scale of synchrony was approximately 400 km when all available data were utilized; much greater than the 50-km scale suggested for freshwater fish populations in an earlier global analysis. The presence of recruitment synchrony between Great Lakes and inland lake cisco populations supports the hypothesis that synchronicity is driven by climate and not dispersal. We also found synchrony in larval densities among three Lake Superior populations separated by 25–275 km, which further supports the hypothesis that broad-scale climatic factors are the cause of spatial synchrony. Among several candidate climate variables measured during the period of larval cisco emergence, maximum wind speeds exhibited the most similar spatial scale of synchrony to that observed for cisco. Other factors, such as average water temperatures, exhibited synchrony on broader spatial scales, which suggests they could also be contributing to recruitment synchrony. Our results provide evidence that abiotic factors can induce synchronous patterns of recruitment for populations of cisco inhabiting waters across a broad geographic range, and show that broad-scale synchrony of recruitment can occur in freshwater fish populations as well as those from marine systems.

  15. Snowpack spatial and temporal variability assessment using SMP high-resolution penetrometer

    NASA Astrophysics Data System (ADS)

    Komarov, Anton; Seliverstov, Yuriy; Sokratov, Sergey; Grebennikov, Pavel

    2017-04-01

    This research is focused on study of spatial and temporal variability of structure and characteristics of snowpack, quick identification of layers based on hardness and dispersion values received from snow micro penetrometer (SMP). We also discuss the detection of weak layers and definition of their parameters in non-alpine terrain. As long as it is the first SMP tool available in Russia, our intent is to test it in different climate and weather conditions. During two separate snowpack studies in plain and mountain landscapes, we derived density and grain size profiles by comparing snow density and grain size from snowpits and SMP measurements. The first case study was MSU meteorological observatory test site in Moscow. SMP data was obtained by 6 consecutive measurements along 10 m transects with a horizontal resolution of approximately 50 cm. The detailed description of snowpack structure, density, grain size, air and snow temperature was also performed. By comparing this information, the detailed scheme of snowpack evolution was created. The second case study was in Khibiny mountains. One 10-meter-long transect was made. SMP, density, grain size and snow temperature data was obtained with horizontal resolution of approximately 50 cm. The high-definition profile of snowpack density variation was acquired using received data. The analysis of data reveals high spatial and temporal variability in snow density and layer structure in both horizontal and vertical dimensions. It indicates that the spatial variability is exhibiting similar spatial patterns as surface topology. This suggests a strong influence from such factors as wind and liquid water pressure on the temporal and spatial evolution of snow structure. It was also defined, that spatial variation of snowpack characteristics is substantial even within homogeneous plain landscape, while in high-latitude mountain regions it grows significantly.

  16. Spin Structures and Phase Diagrams of Extended Spatially Completely Anisotropic Triangular Lattice Antiferromagnets

    NASA Astrophysics Data System (ADS)

    Sakakida, Keishiro; Shimahara, Hiroshi

    2017-12-01

    Motivated by recently discovered organic antiferromagnets, we examine an extended triangular lattice that consists of two types of triangles of bonds with exchange coupling constants Jℓ and J'ℓ (ℓ= 1, 2, and 3), respectively. The simplified system with Jℓ = J'ℓ > 0 is the spatially completely anisotropic triangular lattice (SCATL) antiferromagnet examined previously. The extended system, which we call an extended SCATL (ESCATL), has two different spatial anisotropy parameters J3/J2 and J'3/J'2 when J1 = J'1 is assumed. We derive classical phase diagrams and spin structures. It is found that the ESCATL antiferromagnet exhibits two up-up-down-down (uudd) phases when the imbalance of the anisotropy parameters is significant, in addition to the three Néel phases that occur in the SCATL. When the model parameters vary, these collinear phases are continuously connected by the spiral-spin phase. Using the available model parameters for the organic compounds λ-(BETS)2XCl4 (X = Fe and Ga), we examine the stabilities of the spin structures of the independent π-electron system, which is considered to primarily sustain the magnetic order, where BETS represents bis(ethylenedithio)tetraselenafulvalene. It is found that one of the uudd phases has an energy close to the ground-state energy for λ-(BETS)2FeCl4. We discuss the relevance of the magnetic anion FeCl4 and the quantum fluctuation to the magnetism of these compounds. When J'3 = 0, the system is reduced to a trellis lattice antiferromagnet. The system exhibits a stripe spiral-spin phase, which comprises one-dimensional spiral-spin states stacked alternately.

  17. Methodological Caveats in the Detection of Coordinated Replay between Place Cells and Grid Cells.

    PubMed

    Trimper, John B; Trettel, Sean G; Hwaun, Ernie; Colgin, Laura Lee

    2017-01-01

    At rest, hippocampal "place cells," neurons with receptive fields corresponding to specific spatial locations, reactivate in a manner that reflects recently traveled trajectories. These "replay" events have been proposed as a mechanism underlying memory consolidation, or the transfer of a memory representation from the hippocampus to neocortical regions associated with the original sensory experience. Accordingly, it has been hypothesized that hippocampal replay of a particular experience should be accompanied by simultaneous reactivation of corresponding representations in the neocortex and in the entorhinal cortex, the primary interface between the hippocampus and the neocortex. Recent studies have reported that coordinated replay may occur between hippocampal place cells and medial entorhinal cortex grid cells, cells with multiple spatial receptive fields. Assessing replay in grid cells is problematic, however, as the cells exhibit regularly spaced spatial receptive fields in all environments and, therefore, coordinated replay between place cells and grid cells may be detected by chance. In the present report, we adapted analytical approaches utilized in recent studies of grid cell and place cell replay to determine the extent to which coordinated replay is spuriously detected between grid cells and place cells recorded from separate rats. For a subset of the employed analytical methods, coordinated replay was detected spuriously in a significant proportion of cases in which place cell replay events were randomly matched with grid cell firing epochs of equal duration. More rigorous replay evaluation procedures and minimum spike count requirements greatly reduced the amount of spurious findings. These results provide insights into aspects of place cell and grid cell activity during rest that contribute to false detection of coordinated replay. The results further emphasize the need for careful controls and rigorous methods when testing the hypothesis that place cells and grid cells exhibit coordinated replay.

  18. Diverse responses of different structured forest to drought in Southwest China through remotely sensed data

    NASA Astrophysics Data System (ADS)

    Xu, Peipei; Zhou, Tao; Zhao, Xiang; Luo, Hui; Gao, Shan; Li, Zheng; Cao, Leyao

    2018-07-01

    Global climate change leads to gradual increases in the frequency, intensity, and duration of extreme drought events. Human activities such as afforestation and deforestation have led to spatial variation in forest structure, causing forests to exhibit an age-spatial structure relationship. Thus, it is of great importance to accurately evaluate the effects of drought stress on forest ecosystems with different forest age structures. Because the spatial heterogeneity varies with drought stress intensity, forest age, there are still a lot of uncertainties in current studies. In this study, based on the field measurement, and the proxy index of stand age (based on forest canopy height from LiDAR and stock volume from inventory) at the regional scale, we analyzed the different drought responses of forest ecosystems with various forest ages across different scales in Yunnan province, southwest China from 2001 to 2014. At the local scale, significant differences in the effects of drought stress were found among forests with various ages, suggesting that older forests suffer more under drought stress than younger forests. At the regional scale, the investigation statistics of forest damage indicated a maximum damage ratio in the forest with tall trees (>32 m), whereas damage was minimal in the forest with short trees (<25 m). The stock volume of the forest exhibited the same pattern, that is, the forest damage ratio increased as the stock volume increased. These data demonstrate that the responses of forest drought could be affected by forest age. Under drought stress, older forests show greater vulnerability and risk of damage, which will require special attention for forest managers, as well as improved risk assessments, in the context of future climate change.

  19. Evidence for cue-independent spatial representation in the human auditory cortex during active listening.

    PubMed

    Higgins, Nathan C; McLaughlin, Susan A; Rinne, Teemu; Stecker, G Christopher

    2017-09-05

    Few auditory functions are as important or as universal as the capacity for auditory spatial awareness (e.g., sound localization). That ability relies on sensitivity to acoustical cues-particularly interaural time and level differences (ITD and ILD)-that correlate with sound-source locations. Under nonspatial listening conditions, cortical sensitivity to ITD and ILD takes the form of broad contralaterally dominated response functions. It is unknown, however, whether that sensitivity reflects representations of the specific physical cues or a higher-order representation of auditory space (i.e., integrated cue processing), nor is it known whether responses to spatial cues are modulated by active spatial listening. To investigate, sensitivity to parametrically varied ITD or ILD cues was measured using fMRI during spatial and nonspatial listening tasks. Task type varied across blocks where targets were presented in one of three dimensions: auditory location, pitch, or visual brightness. Task effects were localized primarily to lateral posterior superior temporal gyrus (pSTG) and modulated binaural-cue response functions differently in the two hemispheres. Active spatial listening (location tasks) enhanced both contralateral and ipsilateral responses in the right hemisphere but maintained or enhanced contralateral dominance in the left hemisphere. Two observations suggest integrated processing of ITD and ILD. First, overlapping regions in medial pSTG exhibited significant sensitivity to both cues. Second, successful classification of multivoxel patterns was observed for both cue types and-critically-for cross-cue classification. Together, these results suggest a higher-order representation of auditory space in the human auditory cortex that at least partly integrates the specific underlying cues.

  20. Evidence for cue-independent spatial representation in the human auditory cortex during active listening

    PubMed Central

    McLaughlin, Susan A.; Rinne, Teemu; Stecker, G. Christopher

    2017-01-01

    Few auditory functions are as important or as universal as the capacity for auditory spatial awareness (e.g., sound localization). That ability relies on sensitivity to acoustical cues—particularly interaural time and level differences (ITD and ILD)—that correlate with sound-source locations. Under nonspatial listening conditions, cortical sensitivity to ITD and ILD takes the form of broad contralaterally dominated response functions. It is unknown, however, whether that sensitivity reflects representations of the specific physical cues or a higher-order representation of auditory space (i.e., integrated cue processing), nor is it known whether responses to spatial cues are modulated by active spatial listening. To investigate, sensitivity to parametrically varied ITD or ILD cues was measured using fMRI during spatial and nonspatial listening tasks. Task type varied across blocks where targets were presented in one of three dimensions: auditory location, pitch, or visual brightness. Task effects were localized primarily to lateral posterior superior temporal gyrus (pSTG) and modulated binaural-cue response functions differently in the two hemispheres. Active spatial listening (location tasks) enhanced both contralateral and ipsilateral responses in the right hemisphere but maintained or enhanced contralateral dominance in the left hemisphere. Two observations suggest integrated processing of ITD and ILD. First, overlapping regions in medial pSTG exhibited significant sensitivity to both cues. Second, successful classification of multivoxel patterns was observed for both cue types and—critically—for cross-cue classification. Together, these results suggest a higher-order representation of auditory space in the human auditory cortex that at least partly integrates the specific underlying cues. PMID:28827357

  1. Detection of forest stand-level spatial structure in ectomycorrhizal fungal communities.

    PubMed

    Lilleskov, Erik A; Bruns, Thomas D; Horton, Thomas R; Taylor, D; Grogan, Paul

    2004-08-01

    Ectomycorrhizal fungal (EMF) communities are highly diverse at the stand level. To begin to understand what might lead to such diversity, and to improve sampling designs, we investigated the spatial structure of these communities. We used EMF community data from a number of studies carried out in seven mature and one recently fire-initiated forest stand. We applied various measures of spatial pattern to characterize distributions at EMF community and species levels: Mantel tests, Mantel correlograms, variance/mean and standardized variograms. Mantel tests indicated that in four of eight sites community similarity decreased with distance, whereas Mantel correlograms also found spatial autocorrelation in those four plus two additional sites. In all but one of these sites elevated similarity was evident only at relatively small spatial scales (< 2.6 m), whereas one exhibited a larger scale pattern ( approximately 25 m). Evenness of biomass distribution among cores varied widely among taxa. Standardized variograms indicated that most of the dominant taxa showed patchiness at a scale of less than 3 m, with a range from 0 to < or =17 m. These results have implications for both sampling scale and intensity to achieve maximum efficiency of community sampling. In the systems we examined, cores should be at least 3 m apart to achieve the greatest sampling efficiency for stand-level community analysis. In some cases even this spacing may result in reduced sampling efficiency arising from patterns of spatial autocorrelation. Interpretation of the causes and significance of these patterns requires information on the genetic identity of individuals in the communities.

  2. Beyond Dizziness: Virtual Navigation, Spatial Anxiety and Hippocampal Volume in Bilateral Vestibulopathy

    PubMed Central

    Kremmyda, Olympia; Hüfner, Katharina; Flanagin, Virginia L.; Hamilton, Derek A.; Linn, Jennifer; Strupp, Michael; Jahn, Klaus; Brandt, Thomas

    2016-01-01

    Bilateral vestibulopathy (BVP) is defined as the impairment or loss of function of either the labyrinths or the eighth nerves. Patients with total BVP due to bilateral vestibular nerve section exhibit difficulties in spatial memory and navigation and show a loss of hippocampal volume. In clinical practice, most patients do not have a complete loss of function but rather an asymmetrical residual functioning of the vestibular system. The purpose of the current study was to investigate navigational ability and hippocampal atrophy in BVP patients with residual vestibular function. Fifteen patients with BVP and a group of age- and gender- matched healthy controls were examined. Self-reported questionnaires on spatial anxiety and wayfinding were used to assess the applied strategy of wayfinding and quality of life. Spatial memory and navigation were tested directly using a virtual Morris Water Maze Task. The hippocampal volume of these two groups was evaluated by voxel-based morphometry. In the patients, the questionnaire showed a higher spatial anxiety and the Morris Water Maze Task a delayed spatial learning performance. MRI revealed a significant decrease in the gray matter mid-hippocampal volume (Left: p = 0.006, Z = 4.58, Right: p < 0.001, Z = 3.63) and posterior parahippocampal volume (Right: p = 0.005, Z = 4.65, Left: p < 0.001, Z = 3.87) compared to those of healthy controls. In addition, a decrease in hippocampal formation volume correlated with a more dominant route-finding strategy. Our current findings demonstrate that even partial bilateral vestibular loss leads to anatomical and functional changes in the hippocampal formation and objective and subjective behavioral deficits. PMID:27065838

  3. Spatial distribution of grape root borer (Lepidoptera: Sesiidae) infestations in Virginia vineyards and implications for sampling.

    PubMed

    Rijal, J P; Brewster, C C; Bergh, J C

    2014-06-01

    Grape root borer, Vitacea polistiformis (Harris) (Lepidoptera: Sesiidae) is a potentially destructive pest of grape vines, Vitis spp. in the eastern United States. After feeding on grape roots for ≍2 yr in Virginia, larvae pupate beneath the soil surface around the vine base. Adults emerge during July and August, leaving empty pupal exuviae on or protruding from the soil. Weekly collections of pupal exuviae from an ≍1-m-diameter weed-free zone around the base of a grid of sample vines in Virginia vineyards were conducted in July and August, 2008-2012, and their distribution was characterized using both nonspatial (dispersion) and spatial techniques. Taylor's power law showed a significant aggregation of pupal exuviae, based on data from 19 vineyard blocks. Combined use of geostatistical and Spatial Analysis by Distance IndicEs methods indicated evidence of an aggregated pupal exuviae distribution pattern in seven of the nine blocks used for those analyses. Grape root borer pupal exuviae exhibited spatial dependency within a mean distance of 8.8 m, based on the range values of best-fitted variograms. Interpolated and clustering index-based infestation distribution maps were developed to show the spatial pattern of the insect within the vineyard blocks. The temporal distribution of pupal exuviae showed that the majority of moths emerged during the 3-wk period spanning the third week of July and the first week of August. The spatial distribution of grape root borer pupal exuviae was used in combination with temporal moth emergence patterns to develop a quantitative and efficient sampling scheme to assess infestations.

  4. Exploring links between juvenile offenders and social disorganization at a large map scale: a Bayesian spatial modeling approach

    NASA Astrophysics Data System (ADS)

    Law, Jane; Quick, Matthew

    2013-01-01

    This paper adopts a Bayesian spatial modeling approach to investigate the distribution of young offender residences in York Region, Southern Ontario, Canada, at the census dissemination area level. Few geographic researches have analyzed offender (as opposed to offense) data at a large map scale (i.e., using a relatively small areal unit of analysis) to minimize aggregation effects. Providing context is the social disorganization theory, which hypothesizes that areas with economic deprivation, high population turnover, and high ethnic heterogeneity exhibit social disorganization and are expected to facilitate higher instances of young offenders. Non-spatial and spatial Poisson models indicate that spatial methods are superior to non-spatial models with respect to model fit and that index of ethnic heterogeneity, residential mobility (1 year moving rate), and percentage of residents receiving government transfer payments are, respectively, the most significant explanatory variables related to young offender location. These findings provide overwhelming support for social disorganization theory as it applies to offender location in York Region, Ontario. Targeting areas where prevalence of young offenders could or could not be explained by social disorganization through decomposing the estimated risk map are helpful for dealing with juvenile offenders in the region. Results prompt discussion into geographically targeted police services and young offender placement pertaining to risk of recidivism. We discuss possible reasons for differences and similarities between the previous findings (that analyzed offense data and/or were conducted at a smaller map scale) and our findings, limitations of our study, and practical outcomes of this research from a law enforcement perspective.

  5. Effects of Weaning and Spatial Enrichment on Behavior of Turkish Saanen Goat Kids.

    PubMed

    Tölü, Cemil; Göktürk, Semra; Sava, Türker

    2016-06-01

    As is in all economic activities, the highest yield per unit area is the main goal in animal production, while addressing the temperamental needs of animals often is ignored. Animal welfare is not only an ethical fact; it also has an economic value. Spatial environmental enrichment contributes positively to animal welfare by addressing their behavioral and mental requirements. The present study was conducted to determine the effects of weaning and spatial environmental arrangements on behaviors of goat-kids. Experimental groups were arranged in structured and unstructured spatial environments. Roughage feeder, semi-automatic concentrate feeder, bunk, bridge, and wood block were placed in the structured environment. No equipment was placed in the unstructured environment and paddock sides were enclosed with an iron sheet to prevent bipedal stance and to provide environmental isolation. In the study 10 male and 10 female Turkish Saanen goat kids were used in each group. Spatial environmental arrangements did not have significant impacts on the growth performance of kids (p>0.05). All objects in the structured group were accepted by the kids. Average use ratios of roughage feeder, semi-automatic concentrate feeder, bunk, bridge and wood block were observed as 19.3%, 14.0%, 12.6%, 3.8%, and 0.7%, respectively. There were significant differences between before- and after-weaning in use of all objects except for underneath bridge (p≤0.05). Concentrate feed consumption, locomotion, and resting behaviors in kids showed significant differences by structural group and growth period. Roughage consumption was similar between groups, while it differed by growth period (p≤0.05). Interaction frequency was significantly higher in structured group (p = 0.0023). Playing behavior significantly differentiated based on the growth period rather than on groups (p≤0.05). Playing behavior significantly decreased after weaning. Abnormal oral activity was significantly higher in the structured group before weaning (p≤0.05). Despite there being no installations facilitating climbing and bipedal stance, the kids of the unstructured group were able to exhibit 1/3 as much bipedal stance behavior as the kids of the structured group through leaning over slippery paddock wall or over their groupmates. Bipedal stance behavior of unstructured group was similar before and after weaning, while bipedal stance behavior before weaning was about 2 times that of after weaning in structured group. It was concluded that unstructured environmental arrangement limited the behavior repertoire of the goat kids.

  6. Effects of Weaning and Spatial Enrichment on Behavior of Turkish Saanen Goat Kids

    PubMed Central

    Tölü, Cemil; Göktürk, Semra; Sava, Türker

    2016-01-01

    As is in all economic activities, the highest yield per unit area is the main goal in animal production, while addressing the temperamental needs of animals often is ignored. Animal welfare is not only an ethical fact; it also has an economic value. Spatial environmental enrichment contributes positively to animal welfare by addressing their behavioral and mental requirements. The present study was conducted to determine the effects of weaning and spatial environmental arrangements on behaviors of goat-kids. Experimental groups were arranged in structured and unstructured spatial environments. Roughage feeder, semi-automatic concentrate feeder, bunk, bridge, and wood block were placed in the structured environment. No equipment was placed in the unstructured environment and paddock sides were enclosed with an iron sheet to prevent bipedal stance and to provide environmental isolation. In the study 10 male and 10 female Turkish Saanen goat kids were used in each group. Spatial environmental arrangements did not have significant impacts on the growth performance of kids (p>0.05). All objects in the structured group were accepted by the kids. Average use ratios of roughage feeder, semi-automatic concentrate feeder, bunk, bridge and wood block were observed as 19.3%, 14.0%, 12.6%, 3.8%, and 0.7%, respectively. There were significant differences between before- and after-weaning in use of all objects except for underneath bridge (p≤0.05). Concentrate feed consumption, locomotion, and resting behaviors in kids showed significant differences by structural group and growth period. Roughage consumption was similar between groups, while it differed by growth period (p≤0.05). Interaction frequency was significantly higher in structured group (p = 0.0023). Playing behavior significantly differentiated based on the growth period rather than on groups (p≤0.05). Playing behavior significantly decreased after weaning. Abnormal oral activity was significantly higher in the structured group before weaning (p≤0.05). Despite there being no installations facilitating climbing and bipedal stance, the kids of the unstructured group were able to exhibit 1/3 as much bipedal stance behavior as the kids of the structured group through leaning over slippery paddock wall or over their groupmates. Bipedal stance behavior of unstructured group was similar before and after weaning, while bipedal stance behavior before weaning was about 2 times that of after weaning in structured group. It was concluded that unstructured environmental arrangement limited the behavior repertoire of the goat kids. PMID:26954169

  7. Is the Recall of Verbal-Spatial Information from Working Memory Affected by Symptoms of ADHD?

    ERIC Educational Resources Information Center

    Caterino, Linda C.; Verdi, Michael P.

    2012-01-01

    Objective: The Kulhavy model for text learning using organized spatial displays proposes that learning will be increased when participants view visual images prior to related text. In contrast to previous studies, this study also included students who exhibited symptoms of ADHD. Method: Participants were presented with either a map-text or…

  8. Factors influencing spatial variability in nitrogen processing in nitrogen-saturated soils

    Treesearch

    Frank S. Gilliam; Charles C. Somerville; Nikki L. Lyttle; Mary Beth Adams

    2001-01-01

    Nitrogen (N) saturation is an environmental concern for forests in the eastern U.S. Although several watersheds of the Fernow Experimental Forest (FEF), West Virginia exhibit symptoms of N saturation, many watersheds display a high degree of spatial variability in soil N processing. This study examined the effects of temperature on net N mineralization and...

  9. Bimodal spatial distribution of macular pigment: evidence of a gender relationship

    NASA Astrophysics Data System (ADS)

    Delori, François C.; Goger, Douglas G.; Keilhauer, Claudia; Salvetti, Paola; Staurenghi, Giovanni

    2006-03-01

    The spatial distribution of the optical density of the human macular pigment measured by two-wavelength autofluorescence imaging exhibits in over half of the subjects an annulus of higher density superimposed on a central exponential-like distribution. This annulus is located at about 0.7° from the fovea. Women have broader distributions than men, and they are more likely to exhibit this bimodal distribution. Maxwell's spot reported by subjects matches the measured distribution of their pigment. Evidence that the shape of the foveal depression may be gender related leads us to hypothesize that differences in macular pigment distribution are related to anatomical differences in the shape of the foveal depression.

  10. Mapping of sugar and amino acid availability in soil around roots with bacterial sensors of sucrose and tryptophan

    PubMed

    Jaeger; Lindow; Miller; Clark; Firestone

    1999-06-01

    We developed a technique to map the availability of sugars and amino acids along live roots in an intact soil-root matrix with native microbial soil flora and fauna present. It will allow us to study interactions between root exudates and soil microorganisms at the fine spatial scale necessary to evaluate mechanisms of nitrogen cycling in the rhizosphere. Erwinia herbicola 299R harboring a promoterless ice nucleation reporter gene, driven by either of two nutrient-responsive promoters, was used as a biosensor. Strain 299RTice exhibits tryptophan-dependent ice nucleation activity, while strain 299R(p61RYice) expresses ice nucleation activity proportional to sucrose concentration in its environment. Both biosensors exhibited up to 100-fold differences in ice nucleation activity in response to varying substrate abundance in culture. The biosensors were introduced into the rhizosphere of the annual grass Avena barbata and, as a control, into bulk soil. Neither strain exhibited significant ice nucleation activity in the bulk soil. Both tryptophan and sucrose were detected in the rhizosphere, but they showed different spatial patterns. Tryptophan was apparently most abundant in soil around roots 12 to 16 cm from the tip, while sucrose was most abundant in soil near the root tip. The largest numbers of bacteria (determined by acridine orange staining and direct microscopy) occurred near root sections with the highest apparent sucrose or tryptophan exudation. High sucrose availability at the root tip is consistent with leakage of photosynthate from immature, rapidly growing root tissues, while tryptophan loss from older root sections may result from lateral root perforation of the root epidermis.

  11. [Spatial variability of surface soil nutrients in the landslide area of Beichuan County, South- west China, after 5 · 12 Wenchuan Earthquake].

    PubMed

    Mai, Ji-shan; Zhao, Ting-ning; Zheng, Jiang-kun; Shi, Chang-qing

    2015-12-01

    Based on grid sampling and laboratory analysis, spatial variability of surface soil nutrients was analyzed with GS⁺ and other statistics methods on the landslide area of Fenghuang Mountain, Leigu Town, Beichuan County. The results showed that except for high variability of available phosphorus, other soil nutrients exhibited moderate variability. The ratios of nugget to sill of the soil available phosphorus and soil organic carbon were 27.9% and 28.8%, respectively, showing moderate spatial correlation, while the ratios of nugget to sill of the total nitrogen (20.0%), total phosphorus (24.3%), total potassium (11.1%), available nitrogen (11.2%), and available potassium (22.7%) suggested strong spatial correlation. The total phosphorus had the maximum range (1232.7 m), followed by available nitrogen (541.27 m), total nitrogen (468.35 m), total potassium (136.0 m), available potassium (128.7 m), available phosphorus (116.6 m), and soil organic carbon (93.5 m). Soil nutrients had no significant variation with the increase of altitude, but gradually increased from the landslide area, the transition area, to the little-impacted area. The total and available phosphorus contents of the landslide area decreased by 10.3% and 79.7% compared to that of the little-impacted area, respectively. The soil nutrient contents in the transition area accounted for 31.1%-87.2% of that of the little-impacted area, with the nant reason for the spatial variability of surface soil nutrients.

  12. Temporal Dynamics Assessment of Spatial Overlap Pattern of Functional Brain Networks Reveals Novel Functional Architecture of Cerebral Cortex.

    PubMed

    Jiang, Xi; Li, Xiang; Lv, Jinglei; Zhao, Shijie; Zhang, Shu; Zhang, Wei; Zhang, Tuo; Han, Junwei; Guo, Lei; Liu, Tianming

    2018-06-01

    Various studies in the brain mapping field have demonstrated that there exist multiple concurrent functional networks that are spatially overlapped and interacting with each other during specific task performance to jointly realize the total brain function. Assessing such spatial overlap patterns of functional networks (SOPFNs) based on functional magnetic resonance imaging (fMRI) has thus received increasing interest for brain function studies. However, there are still two crucial issues to be addressed. First, the SOPFNs are assessed over the entire fMRI scan assuming the temporal stationarity, while possibly time-dependent dynamics of the SOPFNs is not sufficiently explored. Second, the SOPFNs are assessed within individual subjects, while group-wise consistency of the SOPFNs is largely unknown. To address the two issues, we propose a novel computational framework of group-wise sparse representation of whole-brain fMRI temporal segments to assess the temporal dynamic spatial patterns of SOPFNs that are consistent across different subjects. Experimental results based on the recently publicly released Human Connectome Project grayordinate task fMRI data demonstrate that meaningful SOPFNs exhibiting dynamic spatial patterns across different time periods are effectively and robustly identified based on the reconstructed concurrent functional networks via the proposed framework. Specifically, those SOPFNs locate significantly more on gyral regions than on sulcal regions across different time periods. These results reveal novel functional architecture of cortical gyri and sulci. Moreover, these results help better understand functional dynamics mechanisms of cerebral cortex in the future.

  13. Understanding taxi travel patterns

    NASA Astrophysics Data System (ADS)

    Cai, Hua; Zhan, Xiaowei; Zhu, Ji; Jia, Xiaoping; Chiu, Anthony S. F.; Xu, Ming

    2016-09-01

    Taxis play important roles in modern urban transportation systems, especially in mega cities. While providing necessary amenities, taxis also significantly contribute to traffic congestion, urban energy consumption, and air pollution. Understanding the travel patterns of taxis is thus important for addressing many urban sustainability challenges. Previous research has primarily focused on examining the statistical properties of passenger trips, which include only taxi trips occupied with passengers. However, unoccupied trips are also important for urban sustainability issues because they represent potential opportunities to improve the efficiency of the transportation system. Therefore, we need to understand the travel patterns of taxis as an integrated system, instead of focusing only on the occupied trips. In this study we examine GPS trajectory data of 11,880 taxis in Beijing, China for a period of three weeks. Our results show that taxi travel patterns share similar traits with travel patterns of individuals but also exhibit differences. Trip displacement distribution of taxi travels is statistically greater than the exponential distribution and smaller than the truncated power-law distribution. The distribution of short trips (less than 30 miles) can be best fitted with power-law while long trips follow exponential decay. We use radius of gyration to characterize individual taxi's travel distance and find that it does not follow a truncated power-law as observed in previous studies. Spatial and temporal regularities exist in taxi travels. However, with increasing spatial coverage, taxi trips can exhibit dual high probability density centers.

  14. Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans

    PubMed Central

    Zhao, Li; Wit, Janneke; Svetec, Nicolas; Begun, David J.

    2015-01-01

    Gene expression variation within species is relatively common, however, the role of natural selection in the maintenance of this variation is poorly understood. Here we investigate low and high latitude populations of Drosophila melanogaster and its sister species, D. simulans, to determine whether the two species show similar patterns of population differentiation, consistent with a role for spatially varying selection in maintaining gene expression variation. We compared at two temperatures the whole male transcriptome of D. melanogaster and D. simulans sampled from Panama City (Panama) and Maine (USA). We observed a significant excess of genes exhibiting differential expression in both species, consistent with parallel adaptation to heterogeneous environments. Moreover, the majority of genes showing parallel expression differentiation showed the same direction of differential expression in the two species and the magnitudes of expression differences between high and low latitude populations were correlated across species, further bolstering the conclusion that parallelism for expression phenotypes results from spatially varying selection. However, the species also exhibited important differences in expression phenotypes. For example, the genomic extent of genotype × environment interaction was much more common in D. melanogaster. Highly differentiated SNPs between low and high latitudes were enriched in the 3’ UTRs and CDS of the geographically differently expressed genes in both species, consistent with an important role for cis-acting variants in driving local adaptation for expression-related phenotypes. PMID:25950438

  15. Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans.

    PubMed

    Zhao, Li; Wit, Janneke; Svetec, Nicolas; Begun, David J

    2015-05-01

    Gene expression variation within species is relatively common, however, the role of natural selection in the maintenance of this variation is poorly understood. Here we investigate low and high latitude populations of Drosophila melanogaster and its sister species, D. simulans, to determine whether the two species show similar patterns of population differentiation, consistent with a role for spatially varying selection in maintaining gene expression variation. We compared at two temperatures the whole male transcriptome of D. melanogaster and D. simulans sampled from Panama City (Panama) and Maine (USA). We observed a significant excess of genes exhibiting differential expression in both species, consistent with parallel adaptation to heterogeneous environments. Moreover, the majority of genes showing parallel expression differentiation showed the same direction of differential expression in the two species and the magnitudes of expression differences between high and low latitude populations were correlated across species, further bolstering the conclusion that parallelism for expression phenotypes results from spatially varying selection. However, the species also exhibited important differences in expression phenotypes. For example, the genomic extent of genotype × environment interaction was much more common in D. melanogaster. Highly differentiated SNPs between low and high latitudes were enriched in the 3' UTRs and CDS of the geographically differently expressed genes in both species, consistent with an important role for cis-acting variants in driving local adaptation for expression-related phenotypes.

  16. Analysis of spatial-temporal patterns of water table change as a tool for conjunctive water management in the Upper Central Plain of the Chao Phraya River Basin, Thailand

    NASA Astrophysics Data System (ADS)

    Vasconcelos, Vitor Vieira; Koontanakulvong, Sucharit; Suthidhummajit, Chokchai; Junior, Paulo Pereira Martins; Hadad, Renato Moreira

    2017-03-01

    A sustainable strategy for conjunctive water management must include information on the temporal and spatial availability of this natural resource. Because of water shortages in the dry seasons, farmers on the Upper Plain of the Chao Phraya River basin, Thailand, are increasingly using groundwater to meet their irrigation needs. To evaluate the possibilities of conjunctive water management in the area, the spatial-temporal changes in the water table of the Younger Terrace Aquifer were investigated. First, a regional geomorphological map based on field surveys, remote sensing and previous environmental studies was developed. Then, the well data were analyzed in relation to rainfall, streamflow, yield and pumpage, and the data were interpolated using geostatistical techniques. The results were analyzed via integrated zoning based on color theory as applied to multivariate visualization. The analysis results indicate areas that would be more suitable for groundwater extraction in a conjunctive management framework with regard to the natural hydrogeological processes and the effects of human interaction. The kriging results were compared with the geomorphological map, and the geomorphological areas exhibit distinct hydrogeological patterns. The western fans exhibit the best potential for the expansion of conjunctive use, whereas the borders of the northern fans exhibit the lowest potential.

  17. A Study of the Microbial Spatial Heterogeneity of Bahamian Thrombolites Using Molecular, Biochemical, and Stable Isotope Analyses

    NASA Astrophysics Data System (ADS)

    Louyakis, Artemis S.; Mobberley, Jennifer M.; Vitek, Brooke E.; Visscher, Pieter T.; Hagan, Paul D.; Reid, R. Pamela; Kozdon, Reinhard; Orland, Ian J.; Valley, John W.; Planavsky, Noah J.; Casaburi, Giorgio; Foster, Jamie S.

    2017-05-01

    Thrombolites are buildups of carbonate that exhibit a clotted internal structure formed through the interactions of microbial mats and their environment. Despite recent advances, we are only beginning to understand the microbial and molecular processes associated with their formation. In this study, a spatial profile of the microbial and metabolic diversity of thrombolite-forming mats of Highborne Cay, The Bahamas, was generated by using 16S rRNA gene sequencing and predictive metagenomic analyses. These molecular-based approaches were complemented with microelectrode profiling and in situ stable isotope analysis to examine the dominant taxa and metabolic activities within the thrombolite-forming communities. Analyses revealed three distinctive zones within the thrombolite-forming mats that exhibited stratified populations of bacteria and archaea. Predictive metagenomics also revealed vertical profiles of metabolic capabilities, such as photosynthesis and carboxylic and fatty acid synthesis within the mats that had not been previously observed. The carbonate precipitates within the thrombolite-forming mats exhibited isotopic geochemical signatures suggesting that the precipitation within the Bahamian thrombolites is photosynthetically induced. Together, this study provides the first look at the spatial organization of the microbial populations within Bahamian thrombolites and enables the distribution of microbes to be correlated with their activities within modern thrombolite systems.

  18. Multi-contamination (heavy metals, polychlorinated biphenyls and polycyclic aromatic hydrocarbons) of littoral sediments and the associated ecological risk assessment in a large lake in France (Lake Bourget).

    PubMed

    Lécrivain, Nathalie; Aurenche, Vincent; Cottin, Nathalie; Frossard, Victor; Clément, Bernard

    2018-04-01

    The lake littoral sediment is exposed to a large array of contaminants that can exhibit significant spatial variability and challenge our ability to assess contamination at lake scale. In this study, littoral sediment contamination was characterized among ten different sites in a large peri-alpine lake (Lake Bourget) regarding three groups of contaminants: 6 heavy metals, 15 polycyclic aromatic hydrocarbons and 7 polychlorinated biphenyls. The contamination profiles significantly varied among sites and differed from those previously reported for the deepest zone of the lake. An integrative approach including chemical and biological analyses was conducted to relate site contamination to ecological risk. The chemical approach consisted in mean PEC quotient calculation (average of the ratios of the contaminants concentration to their corresponding Probable Effect Concentration values) and revealed a low and heterogeneous toxicity of the contaminant mixture along the littoral. Biological analysis including both laboratory (microcosm assays) and in situ (Acetylcholine Esterase (AChE) and Glutathione S-Transferase (GST) activity measurements) experiments highlighted significant differences among sites both in the field and in laboratory assays suggesting a spatial variation of the biota response to contamination. Linear regressions were performed between mean PEC quotients and biological results to assess whether littoral ecological risk was explained by the contamination profiles. The results highly depended on the study benthic or pelagic compartment. Regarding autochthonous Corbicula fluminea, no significant relationship between mean PEC quotients and biomarker activity was found while a significant increase in AChE was observed on autochthonous chironomids, suggesting different stress among benthic organisms. Both AChE and GST in caged pelagic Daphnia magna showed a significant positive relationship with mean PEC quotients. This study underlines the importance of accounting for spatial variations in lake littoral sediment contamination and the need for performing an integrative approach coupling chemical, field and laboratory analyses to assess the ecological risk. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Recent advances in scalable non-Gaussian geostatistics: The generalized sub-Gaussian model

    NASA Astrophysics Data System (ADS)

    Guadagnini, Alberto; Riva, Monica; Neuman, Shlomo P.

    2018-07-01

    Geostatistical analysis has been introduced over half a century ago to allow quantifying seemingly random spatial variations in earth quantities such as rock mineral content or permeability. The traditional approach has been to view such quantities as multivariate Gaussian random functions characterized by one or a few well-defined spatial correlation scales. There is, however, mounting evidence that many spatially varying quantities exhibit non-Gaussian behavior over a multiplicity of scales. The purpose of this minireview is not to paint a broad picture of the subject and its treatment in the literature. Instead, we focus on very recent advances in the recognition and analysis of this ubiquitous phenomenon, which transcends hydrology and the Earth sciences, brought about largely by our own work. In particular, we use porosity data from a deep borehole to illustrate typical aspects of such scalable non-Gaussian behavior, describe a very recent theoretical model that (for the first time) captures all these behavioral aspects in a comprehensive manner, show how this allows generating random realizations of the quantity conditional on sampled values, point toward ways of incorporating scalable non-Gaussian behavior in hydrologic analysis, highlight the significance of doing so, and list open questions requiring further research.

  20. Tracing the phase of focused broadband laser pulses

    NASA Astrophysics Data System (ADS)

    Hoff, Dominik; Krüger, Michael; Maisenbacher, Lothar; Sayler, A. M.; Paulus, Gerhard G.; Hommelhoff, Peter

    2017-10-01

    Precise knowledge of the behaviour of the phase of light in a focused beam is fundamental to understanding and controlling laser-driven processes. More than a hundred years ago, an axial phase anomaly for focused monochromatic light beams was discovered and is now commonly known as the Gouy phase. Recent theoretical work has brought into question the validity of applying this monochromatic phase formulation to the broadband pulses becoming ubiquitous today. Based on electron backscattering at sharp nanometre-scale metal tips, a method is available to measure light fields with sub-wavelength spatial resolution and sub-optical-cycle time resolution. Here we report such a direct, three-dimensional measurement of the spatial dependence of the optical phase of a focused, 4-fs, near-infrared pulsed laser beam. The observed optical phase deviates substantially from the monochromatic Gouy phase--exhibiting a much more complex spatial dependence, both along the propagation axis and in the radial direction. In our measurements, these significant deviations are the rule and not the exception for focused, broadband laser pulses. Therefore, we expect wide ramifications for all broadband laser-matter interactions, such as in high-harmonic and attosecond pulse generation, femtochemistry, ophthalmological optical coherence tomography and light-wave electronics.

  1. Reorienting with terrain slope and landmarks.

    PubMed

    Nardi, Daniele; Newcombe, Nora S; Shipley, Thomas F

    2013-02-01

    Orientation (or reorientation) is the first step in navigation, because establishing a spatial frame of reference is essential for a sense of location and heading direction. Recent research on nonhuman animals has revealed that the vertical component of an environment provides an important source of spatial information, in both terrestrial and aquatic settings. Nonetheless, humans show large individual and sex differences in the ability to use terrain slope for reorientation. To understand why some participants--mainly women--exhibit a difficulty with slope, we tested reorientation in a richer environment than had been used previously, including both a tilted floor and a set of distinct objects that could be used as landmarks. This environment allowed for the use of two different strategies for solving the task, one based on directional cues (slope gradient) and one based on positional cues (landmarks). Overall, rather than using both cues, participants tended to focus on just one. Although men and women did not differ significantly in their encoding of or reliance on the two strategies, men showed greater confidence in solving the reorientation task. These facts suggest that one possible cause of the female difficulty with slope might be a generally lower spatial confidence during reorientation.

  2. Social networks and trade of services: modelling interregional flows with spatial and network autocorrelation effects

    NASA Astrophysics Data System (ADS)

    de la Mata, Tamara; Llano, Carlos

    2013-07-01

    Recent literature on border effect has fostered research on informal barriers to trade and the role played by network dependencies. In relation to social networks, it has been shown that intensity of trade in goods is positively correlated with migration flows between pairs of countries/regions. In this article, we investigate whether such a relation also holds for interregional trade of services. We also consider whether interregional trade flows in services linked with tourism exhibit spatial and/or social network dependence. Conventional empirical gravity models assume the magnitude of bilateral flows between regions is independent of flows to/from regions located nearby in space, or flows to/from regions related through social/cultural/ethic network connections. With this aim, we provide estimates from a set of gravity models showing evidence of statistically significant spatial and network (demographic) dependence in the bilateral flows of the trade of services considered. The analysis has been applied to the Spanish intra- and interregional monetary flows of services from the accommodation, restaurants and travel agencies for the period 2000-2009, using alternative datasets for the migration stocks and definitions of network effects.

  3. Linking Meteorology, Air Quality Models and Observations to ...

    EPA Pesticide Factsheets

    Epidemiologic studies are critical in establishing the association between exposure to air pollutants and adverse health effects. Results of epidemiologic studies are used by U.S. EPA in developing air quality standards to protect the public from the health effects of air pollutants. A major challenge in environmental epidemiology is adequate exposure characterization. Numerous health studies have used measurements from a few central-site ambient monitors to characterize air pollution exposures. Relying solely on central-site ambient monitors does not account for the spatial-heterogeneity of ambient air pollution patterns, the temporal variability in ambient concentrations, nor the influence of infiltration and indoor sources. Central-site monitoring becomes even more problematic for certain air pollutants that exhibit significant spatial heterogeneity. Statistical interpolation techniques and passive monitoring methods can provide additional spatial resolution in ambient concentration estimates. In addition, spatio-temporal models, which integrate GIS data and other factors, such as meteorology, have also been developed to produce more resolved estimates of ambient concentrations. Models, such as the Community Multi-Scale Air Quality (CMAQ) model, estimate ambient concentrations by combining information on meteorology, source emissions, and chemical-fate and transport. Hybrid modeling approaches, which integrate regional scale models with local scale dispersion

  4. Spatial and temporal patterns across an ecological boundary: Allochthonous effects of a young saltwater lake on a desert ecosystem

    USGS Publications Warehouse

    Brehme, C.S.; Boarman, W.I.; Hathaway, S.A.; Herring, A.; Lyren, L.; Mendelsohn, M.; Pease, K.; Rahn, M.; Rochester, C.; Stokes, D.; Turschak, G.; Fisher, R.N.

    2009-01-01

    We documented changes in the abundance and composition of terrestrial flora and fauna with respect to distance from the sea edge and timing of large allochthonous inputs from the Salton Sea, California. We found significant effects that were most pronounced within 300 m of the shore, but extended 3 km inland via coyote scat deposition. The zone within 300 m of the sea had a higher density of vegetation with a distinctly different plant composition. The denser vegetation supported higher abundances of birds and reptiles. Coyotes exhibited spatial and temporal responses to marine subsidies of fish, while birds were likely subsidized by aquatic aerial insects. Top-down control, as well as dietary and habitat preferences, may have resulted in reduced number of ants, beetles, and small mammals near the sea. Species responses to the habitat edge appeared to be associated with life history, as the near shore habitat favored habitat generalists and shore specialists, while inland desert habitat favored many sand and open desert specialists. Ecosystem responses support current theories of allochthonous spatial subsidies and consumer-resource dynamics but were limited in scope, magnitude, and distance.

  5. Flexural subsidence and basement tectonics of the Cretaceous Western Interior basin, United States

    NASA Astrophysics Data System (ADS)

    Pang, Ming; Nummedal, Dag

    1995-02-01

    The flexural subsidence history recorded in Cenomanian to early Campanian (97 to 80 Ma) strata in the Cretaceous U.S. Western Interior basin was studied with two-dimensional flexural backstripping techniques. Results indicate that the flexural subsidence resulting from thrust loading was superimposed on epeirogenic subsidence in the foreland basin. The flexural component exhibits significant spatial and temporal variations along both the strike and dip relative to the Sevier thrust belt. The greatest cumulative subsidence occurred in southwestern Wyoming and northern Utah. Concurrent subsidence in northwestern Montana and southern Utah was insignificant. Temporal trends in subsidence also show a distinct regional pattern. From the Cenomanian to late Turonian (97 to 90 Ma), subsidence rates were high in Utah and much lower in Wyoming and Montana. In contrast, during the Coniacian and Santonian (90 to 85 Ma) subsidence accelerated rapidly in Wyoming, increased slightly in Montana, and decreased in Utah. We suggest that these spatially and temporally varying subsidence patterns reflect the interplay of several geodynamic factors, including: (1) temporal and spatial variation in emplacement of the thrust loads, (2) segmentation of the basement into adjacent blocks with different rheological properties, (3) reactivation of basement fault trends, and (4) regional dynamic topographic effects.

  6. The effect of chrysanthemum leaf trichome density and prey spatial distribution on predation of Tetranychus urticae (Acari: Tetranychidae) by Phytoseiulus persimilis (Acari: Phytoseiidae).

    PubMed

    Skirvin, D J; Stavrinides, M C; Skirvin, D J

    2003-08-01

    The effect of plant architecture, in terms of leaf hairiness, and prey spatial arrangement, on predation rate of eggs of the spider mite, Tetranychus urticae Koch, by the predatory mite Phytoseiulus persimilis Athias-Henriot was examined on cut stems of chrysanthemums. Three levels of leaf hairiness (trichome density) were obtained using two different chrysanthemum cultivars and two ages within one of the cultivars. The number of prey consumed by P. persimilis was inversely related to trichome density. At low prey densities (less than ten eggs per stem), prey consumption did not differ in a biologically meaningful way between treatments. The effect of prey spatial arrangement on the predation rate of P. persimilis was also examined. Predation rates were higher in prey patches on leaves adjacent to the release point of P. persimilis, but significantly greater numbers of prey were consumed in higher density prey patches compared to low density patches. The predators exhibited non-random searching behaviour, spending more time on leaves closest to the release point. The implications of these findings for biological control and predator-prey dynamics are discussed.

  7. Salmon migration patterns revealed the temporal and spatial fluctuations of the radiocesium levels in terrestrial and ocean environments.

    PubMed

    Arai, Takaomi

    2014-01-01

    The disabling of the Fukushima Daiichi Nuclear Power Plant (F1NPP) resulted in the release of radionuclides, including 134Cs and 137Cs, into the air and the ocean. The unpredicted nuclear accident is of global concern for human health and the ecosystem. Although investigations of radionuclides in environments were performed shortly after the accident started, the temporal and spatial impacts and fluctuations on the releasing radionuclides to natural environment remain unclear. I focused on salmon, which migrate from inland to the open ocean globally, to reveal the three-year (May 2011 to February 2014) fluctuations and accumulations of 134Cs and 137Cs from terrestrial to open ocean environments after the F1NPP accident. The 134Cs and 137Cs concentrations in six salmonids exhibited lower temporal variations for three years after the F1NPP accident, suggesting that these radionuclides are widely distributed and these radionuclides remain in the natural environment globally with less convergence. The accumulation patterns were significantly different among the different salmon species. Fluvial (freshwater residence) type salmons exhibited significantly higher accumulation in 134Cs (25.3-40.2 Bq kg(-1) in mean) and 137Cs (41.4-51.7 Bq kg(-1) in mean) than did the anadromous (sea-run) type salmons (0.64-8.03 Bq kg(-1) in mean 134Cs and 0.42-10.2 Bq kg(-1) in mean 137Cs) suggesting widespread contamination in terrestrial environments versus the coastal and open ocean environments. Salmonids are the most highly migratory animals and are characterised by their strong tendency to return home to their natal site for reproduction. Salmonids have a potential to be a good indicator as an effective monitoring animal.

  8. REDOX IMAGING OF THE p53-DEPENDENT MITOCHONDRIAL REDOX STATE IN COLON CANCER EX VIVO

    PubMed Central

    XU, HE N.; FENG, MIN; MOON, LILY; DOLLOFF, NATHAN; EL-DEIRY, WAFIK; LI, LIN Z.

    2015-01-01

    The mitochondrial redox state and its heterogeneity of colon cancer at tissue level have not been previously reported. Nor has how p53 regulates mitochondrial respiration been measured at (deep) tissue level, presumably due to the unavailability of the technology that has sufficient spatial resolution and tissue penetration depth. Our prior work demonstrated that the mitochondrial redox state and its intratumor heterogeneity is associated with cancer aggressiveness in human melanoma and breast cancer in mouse models, with the more metastatic tumors exhibiting localized regions of more oxidized redox state. Using the Chance redox scanner with an in-plane spatial resolution of 200 μm, we imaged the mitochondrial redox state of the wild-type p53 colon tumors (HCT116 p53 wt) and the p53-deleted colon tumors (HCT116 p53−/−) by collecting the fluorescence signals of nicotinamide adenine dinucleotide (NADH) and oxidized flavoproteins [Fp, including flavin adenine dinucleotide (FAD)] from the mouse xenografts snap-frozen at low temperature. Our results show that: (1) both tumor lines have significant degree of intratumor heterogeneity of the redox state, typically exhibiting a distinct bi-modal distribution that either correlates with the spatial core–rim pattern or the “hot/cold” oxidation-reduction patches; (2) the p53−/− group is significantly more heterogeneous in the mitochondrial redox state and has a more oxidized tumor core compared to the p53 wt group when the tumor sizes of the two groups are matched; (3) the tumor size dependence of the redox indices (such as Fp and Fp redox ratio) is significant in the p53−/− group with the larger ones being more oxidized and more heterogeneous in their redox state, particularly more oxidized in the tumor central regions; (4) the H&E staining images of tumor sections grossly correlate with the redox images. The present work is the first to reveal at the submillimeter scale the intratumor heterogeneity pattern of the mitochondrial redox state in colon cancer and the first to indicate that at tissue level the mitochondrial redox state is p53 dependent. The findings should assist in our understanding on colon cancer pathology and developing new imaging biomarkers for clinical applications. PMID:26207147

  9. Assessing spatial coupling in complex population dynamics using mutual prediction and continuity statistics

    USGS Publications Warehouse

    Nichols, J.M.; Moniz, L.; Nichols, J.D.; Pecora, L.M.; Cooch, E.

    2005-01-01

    A number of important questions in ecology involve the possibility of interactions or ?coupling? among potential components of ecological systems. The basic question of whether two components are coupled (exhibit dynamical interdependence) is relevant to investigations of movement of animals over space, population regulation, food webs and trophic interactions, and is also useful in the design of monitoring programs. For example, in spatially extended systems, coupling among populations in different locations implies the existence of redundant information in the system and the possibility of exploiting this redundancy in the development of spatial sampling designs. One approach to the identification of coupling involves study of the purported mechanisms linking system components. Another approach is based on time series of two potential components of the same system and, in previous ecological work, has relied on linear cross-correlation analysis. Here we present two different attractor-based approaches, continuity and mutual prediction, for determining the degree to which two population time series (e.g., at different spatial locations) are coupled. Both approaches are demonstrated on a one-dimensional predator?prey model system exhibiting complex dynamics. Of particular interest is the spatial asymmetry introduced into the model as linearly declining resource for the prey over the domain of the spatial coordinate. Results from these approaches are then compared to the more standard cross-correlation analysis. In contrast to cross-correlation, both continuity and mutual prediction are clearly able to discern the asymmetry in the flow of information through this system.

  10. Conversion of methanol to propylene over hierarchical HZSM-5: the effect of Al spatial distribution.

    PubMed

    Li, Jianwen; Ma, Hongfang; Chen, Yan; Xu, Zhiqiang; Li, Chunzhong; Ying, Weiyong

    2018-06-08

    Different silicon sources caused diverse Al spatial distribution in HZSM-5, and this affected the hierarchical structures and catalytic performance of desilicated zeolites. After being treated with 0.1 M NaOH, HZSM-5 zeolites synthesized with silica sol exhibited relatively widely distributed mesopores and channels, and possessed highly improved propylene selectivity and activity stability.

  11. Roles of dispersal, stochasticity, and nonlinear dynamics in the spatial structuring of seasonal natural enemy-victim populations

    Treesearch

    Patrick C. Tobin; Ottar N. Bjornstad

    2005-01-01

    Natural enemy-victim systems may exhibit a range of dynamic space-time patterns. We used a theoretical framework to study spatiotemporal structuring in a transient natural enemy-victim system subject to differential rates of dispersal, stochastic forcing, and nonlinear dynamics. Highly mobile natural enemies that attacked less mobile victims were locally spatially...

  12. Influence of late-life exposure to environmental enrichmentor exercise on hippocampal function and CA1 senescent physiology

    PubMed Central

    Kumar, A.; Rani, A.; Tchigranova, Olga; Lee, Wei-Hua; Foster, T.C.

    2011-01-01

    Aged (20–22 months) male Fischer 344 rats were randomly assigned to sedentary (A-SED), environmentally enriched (A-ENR) or exercise (A-EX) conditions. After 10–12 weeks of differential experience, the three groups of aged rats and young sedentary controls were tested for physical and cognitive function. Spatial discrimination learning and memory consolidation, tested on the water maze, were enhanced in A-ENR compared to A-SED. A-EX exhibited improved and impaired performance on the cue and spatial task, respectively. Impaired spatial learning in A-EX was likely due to a bias in response selection associated with exercise training, as object recognition memory improved for A-EX rats. An examination of senescent hippocampal physiology revealed that enrichment and exercise reversed age-related changes in long-term depression (LTD) and long-term potentiation (LTP). Rats in the enrichment group exhibited an increase in cell excitability compared to the other two groups of aged animals. The results indicate that differential experience biased the selection of a spatial or a response strategy and factors common across the two conditions, such as increased hippocampal activity associated with locomotion, contribute to reversal of senescent synaptic plasticity. PMID:21820213

  13. [Temporal and spatial distribution of the crab Callinectes sapidus (Decapoda: Portunidae) in Chetumal Bay, Quintana Roo, Mexico].

    PubMed

    Ortiz-León, Héctor J; Jesús-Navarrete, Alberto de; Cordero, Eloy Sosa

    2007-03-01

    In order to determine temporal and spatial distribution patterns of Callinectes sapidus, samplings were carried out during the cold-front (January-February), dry (May-June) and rainy (August-September, 2002) climatic seasons, in 30 sampling stations of Chetumal Bay, grouped in sectors A (14 stations), B (eight stations) and C (eight stations). In each sampling station crabs were collected from two transects parallel to the coast, each with three traps, separated by 30 m. Sediments were calcareous coarse and medium sand, white or lightly gray. A total of 1 031 specimens were collected. CPEU (Capture Per Effort Unit) differed spatially and temporally. Highest CPEU was found in sector C with 1.3 ind.trap(-1), and in the rainy season with 1.1 ind.trap(-1). Population was predominantly composed of male individuals. The male:female ratio was 15:1. Males and adults (group II) CPEU was significant different between sectors and climatic seasons. Both males and adults (group II) had a greater CPEU in sector C (1.2 ind.trap-) and in the rainy season (1.1 ind.trap(-1)). Abundance of female and juvenile individuals (group I) was low during the sampling period whereas group 0 juvenile individuals were not found. A greater relative frequency between sectors and climatic seasons were observed in 130-139 mm and 140-149 mm size interval (CW). C. sapidus occurred on sandy sediments in Chetumal Bay. Pearson product moment correlations exhibited significant relationships between CPEU and temperature, salinity and dissolved oxygen. In Chetumal Bay, the spatial and temporal distribution of C. sapidus can be related to salinity, temperature, habitat quality, food availability, recruitment and reproduction events of individuals.

  14. Enhanced disease characterization through multi network functional normalization in fMRI.

    PubMed

    Çetin, Mustafa S; Khullar, Siddharth; Damaraju, Eswar; Michael, Andrew M; Baum, Stefi A; Calhoun, Vince D

    2015-01-01

    Conventionally, structural topology is used for spatial normalization during the pre-processing of fMRI. The co-existence of multiple intrinsic networks which can be detected in the resting brain are well-studied. Also, these networks exhibit temporal and spatial modulation during cognitive task vs. rest which shows the existence of common spatial excitation patterns between these identified networks. Previous work (Khullar et al., 2011) has shown that structural and functional data may not have direct one-to-one correspondence and functional activation patterns in a well-defined structural region can vary across subjects even for a well-defined functional task. The results of this study and the existence of the neural activity patterns in multiple networks motivates us to investigate multiple resting-state networks as a single fusion template for functional normalization for multi groups of subjects. We extend the previous approach (Khullar et al., 2011) by co-registering multi group of subjects (healthy control and schizophrenia patients) and by utilizing multiple resting-state networks (instead of just one) as a single fusion template for functional normalization. In this paper we describe the initial steps toward using multiple resting-state networks as a single fusion template for functional normalization. A simple wavelet-based image fusion approach is presented in order to evaluate the feasibility of combining multiple functional networks. Our results showed improvements in both the significance of group statistics (healthy control and schizophrenia patients) and the spatial extent of activation when a multiple resting-state network applied as a single fusion template for functional normalization after the conventional structural normalization. Also, our results provided evidence that the improvement in significance of group statistics lead to better accuracy results for classification of healthy controls and schizophrenia patients.

  15. Spontaneous assembly of chemically encoded two-dimensional coacervate droplet arrays by acoustic wave patterning

    PubMed Central

    Tian, Liangfei; Martin, Nicolas; Bassindale, Philip G.; Patil, Avinash J.; Li, Mei; Barnes, Adrian; Drinkwater, Bruce W.; Mann, Stephen

    2016-01-01

    The spontaneous assembly of chemically encoded, molecularly crowded, water-rich micro-droplets into periodic defect-free two-dimensional arrays is achieved in aqueous media by a combination of an acoustic standing wave pressure field and in situ complex coacervation. Acoustically mediated coalescence of primary droplets generates single-droplet per node micro-arrays that exhibit variable surface-attachment properties, spontaneously uptake dyes, enzymes and particles, and display spatial and time-dependent fluorescence outputs when exposed to a reactant diffusion gradient. In addition, coacervate droplet arrays exhibiting dynamical behaviour and exchange of matter are prepared by inhibiting coalescence to produce acoustically trapped lattices of droplet clusters that display fast and reversible changes in shape and spatial configuration in direct response to modulations in the acoustic frequencies and fields. Our results offer a novel route to the design and construction of ‘water-in-water' micro-droplet arrays with controllable spatial organization, programmable signalling pathways and higher order collective behaviour. PMID:27708286

  16. Effects of pharmacological treatments on hippocampal NCAM1 and ERK2 expression in epileptic rats with cognitive dysfunction

    PubMed Central

    Kong, Qingxia; Min, Xia; Sun, Ran; Gao, Jianying; Liang, Ruqing; Li, Lei; Chu, Xu

    2016-01-01

    The present study aimed to investigate the effects of various pharmacological agents on the hippocampal expression of neural cell adhesion molecule 1 (NCAM1) and extracellular signal-regulated kinase 2 (ERK2) in epileptic rats with cognitive dysfunction. The experiments were conducted using 120 Wistar rats: 20 controls and 100 with pilocarpine-induced status epilepticus (SE). The SE rats were randomly assigned to 5 groups (n=20/group) that received daily treatments for 1 month with one of the following: (i) saline (no effect on epilepsy); (ii) carbamazepine (an anticonvulsant); (iii) oxcarbazepine (an anticonvulsant); (iv) aniracetam (a nootropic); or (v) donepezil (an acetylcholinesterase inhibitor). Spatial learning and memory were assessed using a Morris Water Maze (MWM). Hippocampal tissue was assessed for NCAM1 and ERK2 messenger RNA (mRNA) expression by reverse transcription polymerase chain reaction, and protein expression by immunochemistry. The results revealed that SE rats had significantly poorer MWM performances compared with controls (P<0.01). Performance in SE rats was improved with donepezil treatment (P<0.01), but declined with carbamazepine (P<0.01). Compared with controls, saline-treated SE rats exhibited increased hippocampal NCAM1 mRNA expression (P<0.01). Among SE rats, NCAM1 mRNA expression was highest in those treated with donepezil, followed by aniracetam-, saline-, oxcarbazepine- and carbamazepine-treated rats. Compared to controls, saline-treated SE rats exhibited decreased hippocampal ERK2 mRNA expression (P<0.01). Among SE rats, ERK2 mRNA expression was highest in those treated with donepezil, followed by aniracetam, saline, oxcarbazepine and carbamazepine. NCAM1 and ERK2 protein expression levels were parallel to those of the mRNA. In saline-treated SE rats, hippocampal ERK2 expression was decreased and NCAM1 expression was increased; thus, these two molecules may be involved in the impairment of spatial memory. Carbamazepine augmented this impairment, whereas donepezil was found to ameliorate the dysfunction associated with epilepsy. In conclusion, ERK2 and NCAM1 have significant roles in impairment of spatial memory in SE rats. Carbamazepine may increase this impairment, while donepezil may decrease this impairment. PMID:27588125

  17. Current temporal asymmetry and the role of tides: Nan-Wan Bay vs. the Gulf of Elat

    NASA Astrophysics Data System (ADS)

    Ashkenazy, Yosef; Fredj, Erick; Gildor, Hezi; Gong, Gwo-Ching; Lee, Hung-Jen

    2016-05-01

    Nan-Wan Bay in Taiwan and the Gulf of Elat in Israel are two different coastal environments, and as such, their currents are expected to have different statistical properties. While Nan-Wan Bay is shallow, has three open boundaries, and is directly connected to the open ocean, the Gulf of Elat is deep, semi-enclosed, and connected to the Red Sea via the Straits of Tiran. Surface currents have been continuously measured with fine temporal (less than or equal to 1 h) and spatial resolution (less than or equal to 1 km) for more than a year in both environments using coastal radars (CODARs) that cover a domain of roughly 10 × 10 km. These measurements show that the currents in Nan-Wan Bay are much stronger than those in the Gulf of Elat and that the mean current field in Nan-Wan Bay exhibits cyclonic circulation, which is stronger in the summer; in the Gulf of Elat, the mean current field is directed southward and is also stronger during the summer. We have compared the statistical properties of the current speeds in both environments and found that both exhibit large spatial and seasonal variations in the shape parameter of the Weibull distribution. However, we have found fundamental and significant differences when comparing the temporal asymmetry of the current speed (i.e., the ratio between the time during which the current speed increases and the total time). While the Nan-Wan Bay currents are significantly asymmetric, those of the Gulf of Elat are not. We then extracted the tidal component of the Nan-Wan Bay currents and found that it is strongly asymmetric, while the asymmetry of tidally filtered currents is much weaker. We thus conclude that the temporal asymmetry of the Nan-Wan Bay currents reported here is due to the strong tides in the region. We show that the asymmetry ratio in Nan-Wan Bay varies spatially and seasonally: (i) the currents increase rapidly and decay slowly in the northern part of the domain and vice versa in the southern part, and (ii) the asymmetry is stronger during summer.

  18. Evaporative moisture loss from heterogeneous stone: Material-environment interactions during drying

    NASA Astrophysics Data System (ADS)

    McAllister, Daniel; Warke, Patricia; McCabe, Stephen; Gomez-Heras, M.

    2016-11-01

    The complexities of evaporation from structurally and mineralogically heterogeneous sandstone (Locharbriggs Sandstone) are investigated through a laboratory-based experiment in which a variety of environmental conditions are simulated. Data reported demonstrate the significance of material-environment interactions on the spatial and temporal variability of evaporative dynamics. Evaporation from porous stone is determined by the interplay between environmental, material and solution properties, which govern the rate and mode by which water is transmitted to, and subsequently removed from, an evaporating surface. Initially, when the stone is saturated, evaporation is characterized by high rates of moisture loss primarily controlled by external atmospheric conditions. However, as drying progresses, eventually the hydraulic continuity between the stone surface and subsurface is disrupted with recession of the drying front and a decrease in evaporation rates which become reliant on the ability of the material to transport water vapour to the block surface. Pore size distribution and connectivity, as well as other material properties, control the timing of each stage of evaporation and the nature of the transition. These experimental data highlight the complexity of evaporation, demonstrating that different regions of the same stone can exhibit varying moisture dynamics during drying and that the rate and nature of evaporative loss differs under different environmental conditions. The results identify the importance of material-environment interactions during drying and that stone micro-environmental conditions cannot be inferred from ambient data alone. These data have significance for understanding the spatial distribution of stone surface weathering-related morphologies in both the natural and built environments where mineralogical and/or structural heterogeneity creates differences in moisture flux and hence variable drying rates. Such differences may provide a clearer explanation for the initiation and subsequent development of complex weathering responses where areas of significant deterioration can be found alongside areas that exhibit little or no evidence of surface breakdown.

  19. The impact of landscape disturbance on spatial genetic structure in the Guanacaste tree, Enterolobium cyclocarpum (Fabaceae).

    PubMed

    Gonzales, Eva; Hamrick, James L; Smouse, Peter E; Trapnell, Dorset W; Peakall, Rod

    2010-01-01

    We examined spatial genetic structure (SGS) in Enterolobium cyclocarpum (the Guanacaste tree), a dominant tree of Central American dry forests in 4 sites in Guanacaste Province, Costa Rica. In disturbed dry forest sites (e.g., pastures), E. cyclocarpum is primarily dispersed by cattle and horses, whose movements are restricted by pasture boundaries. The study sites varied in tree densities and disturbance. Allozyme analyses of adult trees demonstrated significant levels of SGS in 3 of 4 sites. SGS was primarily due to clusters of young adults located along seasonal streams, rocky areas, and in abandoned pastures. SGS was highest in the first distance class in the least disturbed population, which also had the lowest density of large adults. Low, but significant SGS characterized the site with the highest number of large adults located in individual pastures. The semiurban site, had no clusters of young adults and, probably as a result, failed to exhibit SGS. Our results demonstrate that disturbance can strongly influence SGS patterns and are consistent with a landscape model in which the location of potential recruitment sites, restricted seed disperser movements, and the number and location of maternal individuals dictate the level and pattern of SGS.

  20. Early development of spatial-numeric associations: evidence from spatial and quantitative performance of preschoolers.

    PubMed

    Opfer, John E; Thompson, Clarissa A; Furlong, Ellen E

    2010-09-01

    Numeric magnitudes often bias adults' spatial performance. Partly because the direction of this bias (left-to-right versus right-to-left) is culture-specific, it has been assumed that the orientation of spatial-numeric associations is a late development, tied to reading practice or schooling. Challenging this assumption, we found that preschoolers expected numbers to be ordered from left-to-right when they searched for objects in numbered containers, when they counted, and (to a lesser extent) when they added and subtracted. Further, preschoolers who lacked these biases demonstrated more immature, logarithmic representations of numeric value than preschoolers who exhibited the directional bias, suggesting that spatial-numeric associations aid magnitude representations for symbols denoting increasingly large numbers.

  1. Thermodynamic Model of Spatial Memory

    NASA Astrophysics Data System (ADS)

    Kaufman, Miron; Allen, P.

    1998-03-01

    We develop and test a thermodynamic model of spatial memory. Our model is an application of statistical thermodynamics to cognitive science. It is related to applications of the statistical mechanics framework in parallel distributed processes research. Our macroscopic model allows us to evaluate an entropy associated with spatial memory tasks. We find that older adults exhibit higher levels of entropy than younger adults. Thurstone's Law of Categorical Judgment, according to which the discriminal processes along the psychological continuum produced by presentations of a single stimulus are normally distributed, is explained by using a Hooke spring model of spatial memory. We have also analyzed a nonlinear modification of the ideal spring model of spatial memory. This work is supported by NIH/NIA grant AG09282-06.

  2. Evaluating single-pass catch as a tool for identifying spatial pattern in fish distribution

    USGS Publications Warehouse

    Bateman, Douglas S.; Gresswell, Robert E.; Torgersen, Christian E.

    2005-01-01

    We evaluate the efficacy of single-pass electrofishing without blocknets as a tool for collecting spatially continuous fish distribution data in headwater streams. We compare spatial patterns in abundance, sampling effort, and length-frequency distributions from single-pass sampling of coastal cutthroat trout (Oncorhynchus clarki clarki) to data obtained from a more precise multiple-pass removal electrofishing method in two mid-sized (500–1000 ha) forested watersheds in western Oregon. Abundance estimates from single- and multiple-pass removal electrofishing were positively correlated in both watersheds, r = 0.99 and 0.86. There were no significant trends in capture probabilities at the watershed scale (P > 0.05). Moreover, among-sample variation in fish abundance was higher than within-sample error in both streams indicating that increased precision of unit-scale abundance estimates would provide less information on patterns of abundance than increasing the fraction of habitat units sampled. In the two watersheds, respectively, single-pass electrofishing captured 78 and 74% of the estimated population of cutthroat trout with 7 and 10% of the effort. At the scale of intermediate-sized watersheds, single-pass electrofishing exhibited a sufficient level of precision to be effective in detecting spatial patterns of cutthroat trout abundance and may be a useful tool for providing the context for investigating fish-habitat relationships at multiple scales.

  3. The neural substrates of deliberative decision making: contrasting effects of hippocampus lesions on performance and vicarious trial-and-error behavior in a spatial memory task and a visual discrimination task

    PubMed Central

    Bett, David; Allison, Elizabeth; Murdoch, Lauren H.; Kaefer, Karola; Wood, Emma R.; Dudchenko, Paul A.

    2012-01-01

    Vicarious trial-and-errors (VTEs) are back-and-forth movements of the head exhibited by rodents and other animals when faced with a decision. These behaviors have recently been associated with prospective sweeps of hippocampal place cell firing, and thus may reflect a rodent model of deliberative decision-making. The aim of the current study was to test whether the hippocampus is essential for VTEs in a spatial memory task and in a simple visual discrimination (VD) task. We found that lesions of the hippocampus with ibotenic acid produced a significant impairment in the accuracy of choices in a serial spatial reversal (SR) task. In terms of VTEs, whereas sham-lesioned animals engaged in more VTE behavior prior to identifying the location of the reward as opposed to repeated trials after it had been located, the lesioned animals failed to show this difference. In contrast, damage to the hippocampus had no effect on acquisition of a VD or on the VTEs seen in this task. For both lesion and sham-lesion animals, adding an additional choice to the VD increased the number of VTEs and decreased the accuracy of choices. Together, these results suggest that the hippocampus may be specifically involved in VTE behavior during spatial decision making. PMID:23115549

  4. History of Reading Struggles Linked to Enhanced Learning in Low Spatial Frequency Scenes

    PubMed Central

    Schneps, Matthew H.; Brockmole, James R.; Sonnert, Gerhard; Pomplun, Marc

    2012-01-01

    People with dyslexia, who face lifelong struggles with reading, exhibit numerous associated low-level sensory deficits including deficits in focal attention. Countering this, studies have shown that struggling readers outperform typical readers in some visual tasks that integrate distributed information across an expanse. Though such abilities would be expected to facilitate scene memory, prior investigations using the contextual cueing paradigm failed to find corresponding advantages in dyslexia. We suggest that these studies were confounded by task-dependent effects exaggerating known focal attention deficits in dyslexia, and that, if natural scenes were used as the context, advantages would emerge. Here, we investigate this hypothesis by comparing college students with histories of severe lifelong reading difficulties (SR) and typical readers (TR) in contexts that vary attention load. We find no differences in contextual-cueing when spatial contexts are letter-like objects, or when contexts are natural scenes. However, the SR group significantly outperforms the TR group when contexts are low-pass filtered natural scenes [F(3, 39) = 3.15, p<.05]. These findings suggest that perception or memory for low spatial frequency components in scenes is enhanced in dyslexia. These findings are important because they suggest strengths for spatial learning in a population otherwise impaired, carrying implications for the education and support of students who face challenges in school. PMID:22558210

  5. A Sensitive Method for Examining Whole Cell Biochemical Composition in Single Cells of Filamentous Fungi using Synchrotron FTIR Spectromicroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Konstantin,J.; Gough, K.; Julian, R.

    2008-01-01

    Cell function is related to cell composition. The asexual state of filamentous fungi (molds and mildews) has two main life cycle stages: vegetative hyphae for substrate colonization and nutrient acquisition, and asexual spores for survival and dispersal. Hyphal composition changes over a few tens of microns during growth and maturation; spores are different from hyphae. Most biochemical analyses are restricted to studying a few components at high spatial resolution (e.g. histochemistry) or many compounds at low spatial resolution (e.g. GC-MS). Synchrotron FTIR spectromicroscopy can be used to study fungal cell biology by fingerprinting varieties of carbohydrates, proteins, and lipids atmore » about 6 microm spatial resolution. FTIR can distinguish fungal species and changes during hyphal growth, and reveals that even fungi grown under optimal vs mildly stressed conditions exhibit dramatic biochemical changes without obvious morphological effects. Here we compare hypha and spore composition of two fungi, Neurospora and Rhizopus. There are clear biochemical changes when Neurospora hyphae commit to spore development, during spore maturation and following germination, many of which are consistent with results from molecular genetics, but have not been shown before at high spatial resolution. Rhizopus spores develop within a fluid-containing sporangium that becomes dry at maturity. Rhizopus spores had similar protein content and significantly more carbohydrate than the sporangial fluid, both of which are novel findings.« less

  6. History of reading struggles linked to enhanced learning in low spatial frequency scenes.

    PubMed

    Schneps, Matthew H; Brockmole, James R; Sonnert, Gerhard; Pomplun, Marc

    2012-01-01

    People with dyslexia, who face lifelong struggles with reading, exhibit numerous associated low-level sensory deficits including deficits in focal attention. Countering this, studies have shown that struggling readers outperform typical readers in some visual tasks that integrate distributed information across an expanse. Though such abilities would be expected to facilitate scene memory, prior investigations using the contextual cueing paradigm failed to find corresponding advantages in dyslexia. We suggest that these studies were confounded by task-dependent effects exaggerating known focal attention deficits in dyslexia, and that, if natural scenes were used as the context, advantages would emerge. Here, we investigate this hypothesis by comparing college students with histories of severe lifelong reading difficulties (SR) and typical readers (TR) in contexts that vary attention load. We find no differences in contextual-cueing when spatial contexts are letter-like objects, or when contexts are natural scenes. However, the SR group significantly outperforms the TR group when contexts are low-pass filtered natural scenes [F(3, 39) = 3.15, p<.05]. These findings suggest that perception or memory for low spatial frequency components in scenes is enhanced in dyslexia. These findings are important because they suggest strengths for spatial learning in a population otherwise impaired, carrying implications for the education and support of students who face challenges in school.

  7. Coupling fine-scale root and canopy structure using ground-based remote sensing

    DOE PAGES

    Hardiman, Brady S.; Gough, Christopher M.; Butnor, John R.; ...

    2017-02-21

    Ecosystem physical structure, defined by the quantity and spatial distribution of biomass, influences a range of ecosystem functions. Remote sensing tools permit the non-destructive characterization of canopy and root features, potentially providing opportunities to link above- and belowground structure at fine spatial resolution in functionally meaningful ways. To test this possibility, we employed ground-based portable canopy LiDAR (PCL) and ground penetrating radar (GPR) along co-located transects in forested sites spanning multiple stages of ecosystem development and, consequently, of structural complexity. We examined canopy and root structural data for coherence (i.e., correlation in the frequency of spatial variation) at multiple spatialmore » scales 10 m within each site using wavelet analysis. Forest sites varied substantially in vertical canopy and root structure, with leaf area index and root mass more becoming even vertically as forests aged. In all sites, above- and belowground structure, characterized as mean maximum canopy height and root mass, exhibited significant coherence at a scale of 3.5–4 m, and results suggest that the scale of coherence may increase with stand age. Our findings demonstrate that canopy and root structure are linked at characteristic spatial scales, which provides the basis to optimize scales of observation. Lastly, our study highlights the potential, and limitations, for fusing LiDAR and radar technologies to quantitatively couple above- and belowground ecosystem structure.« less

  8. Coupling fine-scale root and canopy structure using ground-based remote sensing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hardiman, Brady S.; Gough, Christopher M.; Butnor, John R.

    Ecosystem physical structure, defined by the quantity and spatial distribution of biomass, influences a range of ecosystem functions. Remote sensing tools permit the non-destructive characterization of canopy and root features, potentially providing opportunities to link above- and belowground structure at fine spatial resolution in functionally meaningful ways. To test this possibility, we employed ground-based portable canopy LiDAR (PCL) and ground penetrating radar (GPR) along co-located transects in forested sites spanning multiple stages of ecosystem development and, consequently, of structural complexity. We examined canopy and root structural data for coherence (i.e., correlation in the frequency of spatial variation) at multiple spatialmore » scales 10 m within each site using wavelet analysis. Forest sites varied substantially in vertical canopy and root structure, with leaf area index and root mass more becoming even vertically as forests aged. In all sites, above- and belowground structure, characterized as mean maximum canopy height and root mass, exhibited significant coherence at a scale of 3.5–4 m, and results suggest that the scale of coherence may increase with stand age. Our findings demonstrate that canopy and root structure are linked at characteristic spatial scales, which provides the basis to optimize scales of observation. Lastly, our study highlights the potential, and limitations, for fusing LiDAR and radar technologies to quantitatively couple above- and belowground ecosystem structure.« less

  9. Use of forecasting signatures to help distinguish periodicity, randomness, and chaos in ripples and other spatial patterns

    USGS Publications Warehouse

    Rubin, D.M.

    1992-01-01

    Forecasting of one-dimensional time series previously has been used to help distinguish periodicity, chaos, and noise. This paper presents two-dimensional generalizations for making such distinctions for spatial patterns. The techniques are evaluated using synthetic spatial patterns and then are applied to a natural example: ripples formed in sand by blowing wind. Tests with the synthetic patterns demonstrate that the forecasting techniques can be applied to two-dimensional spatial patterns, with the same utility and limitations as when applied to one-dimensional time series. One limitation is that some combinations of periodicity and randomness exhibit forecasting signatures that mimic those of chaos. For example, sine waves distorted with correlated phase noise have forecasting errors that increase with forecasting distance, errors that, are minimized using nonlinear models at moderate embedding dimensions, and forecasting properties that differ significantly between the original and surrogates. Ripples formed in sand by flowing air or water typically vary in geometry from one to another, even when formed in a flow that is uniform on a large scale; each ripple modifies the local flow or sand-transport field, thereby influencing the geometry of the next ripple downcurrent. Spatial forecasting was used to evaluate the hypothesis that such a deterministic process - rather than randomness or quasiperiodicity - is responsible for the variation between successive ripples. This hypothesis is supported by a forecasting error that increases with forecasting distance, a greater accuracy of nonlinear relative to linear models, and significant differences between forecasts made with the original ripples and those made with surrogate patterns. Forecasting signatures cannot be used to distinguish ripple geometry from sine waves with correlated phase noise, but this kind of structure can be ruled out by two geometric properties of the ripples: Successive ripples are highly correlated in wavelength, and ripple crests display dislocations such as branchings and mergers. ?? 1992 American Institute of Physics.

  10. Spatial clusters of daytime sleepiness and association with nighttime noise levels in a Swiss general population (GeoHypnoLaus).

    PubMed

    Joost, Stéphane; Haba-Rubio, José; Himsl, Rebecca; Vollenweider, Peter; Preisig, Martin; Waeber, Gérard; Marques-Vidal, Pedro; Heinzer, Raphaël; Guessous, Idris

    2018-05-31

    Daytime sleepiness is highly prevalent in the general adult population and has been linked to an increased risk of workplace and vehicle accidents, lower professional performance and poorer health. Despite the established relationship between noise and daytime sleepiness, little research has explored the individual-level spatial distribution of noise-related sleep disturbances. We assessed the spatial dependence of daytime sleepiness and tested whether clusters of individuals exhibiting higher daytime sleepiness were characterized by higher nocturnal noise levels than other clusters. Population-based cross-sectional study, in the city of Lausanne, Switzerland. Sleepiness was measured using the Epworth Sleepiness Scale (ESS) for 3697 georeferenced individuals from the CoLaus|PsyCoLaus cohort (period = 2009-2012). We used the sonBASE georeferenced database produced by the Swiss Federal Office for the Environment to characterize nighttime road traffic noise exposure throughout the city. We used the GeoDa software program to calculate the Getis-Ord G i * statistics for unadjusted and adjusted ESS in order to detect spatial clusters of high and low ESS values. Modeled nighttime noise exposure from road and rail traffic was compared across ESS clusters. Daytime sleepiness was not randomly distributed and showed a significant spatial dependence. The median nighttime traffic noise exposure was significantly different across the three ESS Getis cluster classes (p < 0.001). The mean nighttime noise exposure in the high ESS cluster class was 47.6, dB(A) 5.2 dB(A) higher than in low clusters (p < 0.001) and 2.1 dB(A) higher than in the neutral class (p < 0.001). These associations were independent of major potential confounders including body mass index and neighborhood income level. Clusters of higher daytime sleepiness in adults are associated with higher median nighttime noise levels. The identification of these clusters can guide tailored public health interventions. Copyright © 2018 The Authors. Published by Elsevier GmbH.. All rights reserved.

  11. Investigation of Kibble-Zurek Quench Dynamics in a Spin-1 Ferromagnetic BEC

    NASA Astrophysics Data System (ADS)

    Anquez, Martin; Robbins, Bryce; Hoang, Thai; Yang, Xiaoyun; Land, Benjamin; Hamley, Christopher; Chapman, Michael

    2014-05-01

    We study the temporal evolution of spin populations in small spin-1 87Rb condensates following a slow quench. A ferromagnetic spin-1 BEC exhibits a second-order gapless (quantum) phase transition due to a competition between the magnetic and collisional spin interaction energies. The dynamics of slow quenches through the critical point are predicted to exhibit universal power-law scaling as a function of quench speed. In spatially extended condensates, these excitations are revealed as spatial spin domains. In small condensates, the excitations are manifest in the temporal evolution of the spin populations, illustrating a Kibble-Zurek type scaling. We will present the results of our investigation and compare them to full quantum simulations of the system.

  12. Comparison and Evaluation of Annual NDVI Time Series in China Derived from the NOAA AVHRR LTDR and Terra MODIS MOD13C1 Products

    PubMed Central

    Guo, Xiaoyi; Zhang, Hongyan; Wu, Zhengfang; Zhao, Jianjun; Zhang, Zhengxiang

    2017-01-01

    Time series of Normalized Difference Vegetation Index (NDVI) derived from multiple satellite sensors are crucial data to study vegetation dynamics. The Land Long Term Data Record Version 4 (LTDR V4) NDVI dataset was recently released at a 0.05 × 0.05° spatial resolution and daily temporal resolution. In this study, annual NDVI time series that are composited by the LTDR V4 and Moderate Resolution Imaging Spectroradiometer (MODIS) NDVI datasets (MOD13C1) are compared and evaluated for the period from 2001 to 2014 in China. The spatial patterns of the NDVI generally match between the LTDR V4 and MOD13C1 datasets. The transitional zone between high and low NDVI values generally matches the boundary of semi-arid and sub-humid regions. A significant and high coefficient of determination is found between the two datasets according to a pixel-based correlation analysis. The spatially averaged NDVI of LTDR V4 is characterized by a much weaker positive regression slope relative to that of the spatially averaged NDVI of the MOD13C1 dataset because of changes in NOAA AVHRR sensors between 2005 and 2006. The measured NDVI values of LTDR V4 were always higher than that of MOD13C1 in western China due to the relatively lower atmospheric water vapor content in western China, and opposite observation appeared in eastern China. In total, 18.54% of the LTDR V4 NDVI pixels exhibit significant trends, whereas 35.79% of the MOD13C1 NDVI pixels show significant trends. Good agreement is observed between the significant trends of the two datasets in the Northeast Plain, Bohai Economic Rim, Loess Plateau, and Yangtze River Delta. By contrast, the datasets contrasted in northwestern desert regions and southern China. A trend analysis of the regression slope values according to the vegetation type shows good agreement between the LTDR V4 and MOD13C1 datasets. This study demonstrates the spatial and temporal consistencies and discrepancies between the AVHRR LTDR and MODIS MOD13C1 NDVI products in China, which could provide useful information for the choice of NDVI products in subsequent studies of vegetation dynamics. PMID:28587266

  13. Comparison and Evaluation of Annual NDVI Time Series in China Derived from the NOAA AVHRR LTDR and Terra MODIS MOD13C1 Products.

    PubMed

    Guo, Xiaoyi; Zhang, Hongyan; Wu, Zhengfang; Zhao, Jianjun; Zhang, Zhengxiang

    2017-06-06

    Time series of Normalized Difference Vegetation Index (NDVI) derived from multiple satellite sensors are crucial data to study vegetation dynamics. The Land Long Term Data Record Version 4 (LTDR V4) NDVI dataset was recently released at a 0.05 × 0.05° spatial resolution and daily temporal resolution. In this study, annual NDVI time series that are composited by the LTDR V4 and Moderate Resolution Imaging Spectroradiometer (MODIS) NDVI datasets (MOD13C1) are compared and evaluated for the period from 2001 to 2014 in China. The spatial patterns of the NDVI generally match between the LTDR V4 and MOD13C1 datasets. The transitional zone between high and low NDVI values generally matches the boundary of semi-arid and sub-humid regions. A significant and high coefficient of determination is found between the two datasets according to a pixel-based correlation analysis. The spatially averaged NDVI of LTDR V4 is characterized by a much weaker positive regression slope relative to that of the spatially averaged NDVI of the MOD13C1 dataset because of changes in NOAA AVHRR sensors between 2005 and 2006. The measured NDVI values of LTDR V4 were always higher than that of MOD13C1 in western China due to the relatively lower atmospheric water vapor content in western China, and opposite observation appeared in eastern China. In total, 18.54% of the LTDR V4 NDVI pixels exhibit significant trends, whereas 35.79% of the MOD13C1 NDVI pixels show significant trends. Good agreement is observed between the significant trends of the two datasets in the Northeast Plain, Bohai Economic Rim, Loess Plateau, and Yangtze River Delta. By contrast, the datasets contrasted in northwestern desert regions and southern China. A trend analysis of the regression slope values according to the vegetation type shows good agreement between the LTDR V4 and MOD13C1 datasets. This study demonstrates the spatial and temporal consistencies and discrepancies between the AVHRR LTDR and MODIS MOD13C1 NDVI products in China, which could provide useful information for the choice of NDVI products in subsequent studies of vegetation dynamics.

  14. Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep

    PubMed Central

    Villalobos, Claudio

    2017-01-01

    Spatial memory, among many other brain processes, shows hemispheric lateralization. Most of the published evidence suggests that the right hippocampus plays a leading role in the manipulation of spatial information. Concurrently in the hippocampus, memory consolidation during sleep periods is one of the key steps in the formation of newly acquired spatial memory traces. One of the most characteristic oscillatory patterns in the hippocampus are sharp-wave ripple (SWR) complexes. Within this complex, fast-field oscillations or ripples have been demonstrated to be instrumental in the memory consolidation process. Since these ripples are relevant for the consolidation of memory traces associated with spatial navigation, and this process appears to be lateralized, we hypothesize that ripple events between both hippocampi would exhibit different temporal dynamics. We tested this idea by using a modified "split-hyperdrive" that allows us to record simultaneous LFPs from both right and left hippocampi of Sprague-Dawley rats during sleep. We detected individual events and found that during sleep periods these ripples exhibited a different occurrence patterns between hemispheres. Most ripple events were synchronous between intra- rather than inter-hemispherical recordings, suggesting that ripples in the hippocampus are independently generated and locally propagated within a specific hemisphere. In this study, we propose the ripples’ lack of synchrony between left and right hippocampi as the putative physiological mechanism underlying lateralization of spatial memory. PMID:28158285

  15. Asynchronous ripple oscillations between left and right hippocampi during slow-wave sleep.

    PubMed

    Villalobos, Claudio; Maldonado, Pedro E; Valdés, José L

    2017-01-01

    Spatial memory, among many other brain processes, shows hemispheric lateralization. Most of the published evidence suggests that the right hippocampus plays a leading role in the manipulation of spatial information. Concurrently in the hippocampus, memory consolidation during sleep periods is one of the key steps in the formation of newly acquired spatial memory traces. One of the most characteristic oscillatory patterns in the hippocampus are sharp-wave ripple (SWR) complexes. Within this complex, fast-field oscillations or ripples have been demonstrated to be instrumental in the memory consolidation process. Since these ripples are relevant for the consolidation of memory traces associated with spatial navigation, and this process appears to be lateralized, we hypothesize that ripple events between both hippocampi would exhibit different temporal dynamics. We tested this idea by using a modified "split-hyperdrive" that allows us to record simultaneous LFPs from both right and left hippocampi of Sprague-Dawley rats during sleep. We detected individual events and found that during sleep periods these ripples exhibited a different occurrence patterns between hemispheres. Most ripple events were synchronous between intra- rather than inter-hemispherical recordings, suggesting that ripples in the hippocampus are independently generated and locally propagated within a specific hemisphere. In this study, we propose the ripples' lack of synchrony between left and right hippocampi as the putative physiological mechanism underlying lateralization of spatial memory.

  16. Locational Determinants of Emissions from Pollution-Intensive Firms in Urban Areas

    PubMed Central

    Zhou, Min; Tan, Shukui; Guo, Mingjing; Zhang, Lu

    2015-01-01

    Industrial pollution has remained as one of the most daunting challenges for many regions around the world. Characterizing the determinants of industrial pollution should provide important management implications. Unfortunately, due to the absence of high-quality data, rather few studies have systematically examined the locational determinants using a geographical approach. This paper aimed to fill the gap by accessing the pollution source census dataset, which recorded the quantity of discharged wastes (waste water and solid waste) from 717 pollution-intensive firms within Huzhou City, China. Spatial exploratory analysis was applied to analyze the spatial dependency and local clusters of waste emissions. Results demonstrated that waste emissions presented significantly positive autocorrelation in space. The high-high hotspots generally concentrated towards the city boundary, while the low-low clusters approached the Taihu Lake. Their locational determinants were identified by spatial regression. In particular, firms near the city boundary and county road were prone to discharge more wastes. Lower waste emissions were more likely to be observed from firms with high proximity to freight transfer stations or the Taihu Lake. Dense populous districts saw more likelihood of solid waste emissions. Firms in the neighborhood of rivers exhibited higher waste water emissions. Besides, the control variables (firm size, ownership, operation time and industrial type) also exerted significant influence. The present methodology can be applicable to other areas, and further inform the industrial pollution control practices. Our study advanced the knowledge of determinants of emissions from pollution-intensive firms in urban areas. PMID:25927438

  17. Spatiotemporal variation in survival rates: implications for population dynamics of yellow-bellied marmots.

    PubMed

    Ozgul, Arpat; Armitage, Kenneth B; Blumstein, Daniel T; Oli, Madan K

    2006-04-01

    Spatiotemporal variation in age-specific survival rates can profoundly influence population dynamics, but few studies of vertebrates have thoroughly investigated both spatial and temporal variability in age-specific survival rates. We used 28 years (1976-2003) of capture-mark-recapture (CMR) data from 17 locations to parameterize an age-structured Cormack-Jolly-Seber model, and investigated spatial and temporal variation in age-specific annual survival rates of yellow-bellied marmots (Marmota flaviventris). Survival rates varied both spatially and temporally, with survival of younger animals exhibiting the highest degree of variation. Juvenile survival rates varied from 0.52 +/- 0.05 to 0.78 +/- 0.10 among sites and from 0.15 +/- 0.14 to 0.89 +/- 0.06 over time. Adult survival rates varied from 0.62 +/- 0.09 to 0.80 +/- 0.03 among sites, but did not vary significantly over time. We used reverse-time CMR models to estimate the realized population growth rate (lamda), and to investigate the influence of the observed variation in age-specific survival rates on lamda. The realized growth rate of the population closely covaried with, and was significantly influenced by, spatiotemporal variation in juvenile survival rate. High variability in juvenile survival rates over space and time clearly influenced the dynamics of our study population and is also likely to be an important determinant of the spatiotemporal variation in the population dynamics of other mammals with similar life history characteristics.

  18. What can we learn from the self-attraction and loading fingerprints about pre-GRACE mass-loss acceleration from Greenland and Antarctica?

    NASA Astrophysics Data System (ADS)

    Davis, J. L.; Vinogradova, N. T.

    2017-12-01

    Tide-gauge records from the North Atlantic reveal significant acceleration in sea level starting in the late 20th century. We have analyzed the tide-gauge data using a model in which the accelerations are assumed to be zero prior to 1990. The estimated accelerations range from -1 to +3 m cy-2 and exhibit a systematic spatial variability. Davis and Vinogradova [2017] demonstrated that to model this variability in sea-level acceleration requires contributions from several distinct physical processes: accelerated mass loss from the Greenland and Antarctic Ice Sheets and acceleration associated with ocean circulation and heat uptake. Atmospheric pressure also contributes to the observed changes in sea level, at a much smaller amplitude. Because we are focusing on sea-level accelerations (i.e., sea-level rate changes), the contribution from Glacial Isostatic Adjustment (GIA) is negligible. Modeling of observed sea-level acceleration is achieved using external constraints for the important physical processes. Using GRACE results, we can calculate the sea-level "fingerprints" for Greenland and Antarctica associated with mass loading and gravitational perturbations. For the North Atlantic, Greenland induces a significant spatial variation in sea-level change—dominated by the solid-Earth response to the mass loss—whereas Antarctica contributes a spatially constant acceleration. The observations prefer a scaling of the solid-Earth/gravitational response, and we present the implications of this result for ice-mass changes prior to the onset of GRACE observations (2002-3).

  19. High spatial resolution distributed optical fiber dynamic strain sensor with enhanced frequency and strain resolution.

    PubMed

    Masoudi, Ali; Newson, Trevor P

    2017-01-15

    A distributed optical fiber dynamic strain sensor with high spatial and frequency resolution is demonstrated. The sensor, which uses the ϕ-OTDR interrogation technique, exhibited a higher sensitivity thanks to an improved optical arrangement and a new signal processing procedure. The proposed sensing system is capable of fully quantifying multiple dynamic perturbations along a 5 km long sensing fiber with a frequency and spatial resolution of 5 Hz and 50 cm, respectively. The strain resolution of the sensor was measured to be 40 nε.

  20. Differential shift in spatial bias over time depends on observers׳ initial bias: Observer subtypes, or regression to the mean?

    PubMed

    Newman, Daniel P; Loughnane, Gerard M; Abe, Rafael; Zoratti, Marco T R; Martins, Ana C P; van den Bogert, Petra C; Kelly, Simon P; O'Connell, Redmond G; Bellgrove, Mark A

    2014-11-01

    Healthy subjects typically exhibit a subtle bias of visuospatial attention favouring left space that is commonly termed 'pseudoneglect'. This bias is attenuated, or shifted rightwards, with decreasing alertness over time, consistent with theoretical models proposing that pseudoneglect is a result of the right hemisphere׳s dominance in regulating attention. Although this 'time-on-task effect' for spatial bias is observed when averaging across whole samples of healthy participants, Benwell, C. S. Y., Thut, G., Learmonth, G., & Harvey, M. (2013b). Spatial attention: differential shifts in pseudoneglect direction with time-on-task and initial bias support the idea of observer subtypes. Neuropsychologia, 51(13), 2747-2756 recently presented evidence that the direction and magnitude of bias exhibited by the participant early in the task (left biased, no bias, or right biased) were stable traits that predicted the direction of the subsequent time-on-task shift in spatial bias. That is, the spatial bias of participants who were initially left biased shifted in a rightward direction with time, whereas that of participants who were initially right biased shifted in a leftward direction. If valid, the data of Benwell et al. are potentially important and may demand a re-evaluation of current models of the neural networks governing spatial attention. Here we use two novel spatial attention tasks in an attempt to confirm the results of Benwell et al. We show that rather than being indicative of true participant subtypes, these data patterns are likely driven, at least in part, by 'regression towards the mean' arising from the analysis method employed. Although evidence supports the contention that trait-like individual differences in spatial bias exist within the healthy population, no clear evidence is yet available for participant/observer subtypes in the direction of time-on-task shift in spatial biases. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Spatial relationships among cereal yields and selected soil physical and chemical properties.

    PubMed

    Lipiec, Jerzy; Usowicz, Bogusław

    2018-08-15

    Sandy soils occupy large area in Poland (about 50%) and in the world. This study aimed at determining spatial relationships of cereal yields and the selected soil physical and chemical properties in three study years (2001-2003) on low productive sandy Podzol soil (Podlasie, Poland). The yields and soil properties in plough and subsoil layers were determined at 72-150 points. The test crops were: wheat, wheat and barley mixture and oats. To explore the spatial relationship between cereal yields and each soil property spatial statistics was used. The best fitting models were adjusted to empirical semivariance and cross-semivariance, which were used to draw maps using kriging. Majority of the soil properties and crop yields exhibited low and medium variability (coefficient of variation 5-70%). The effective ranges of the spatial dependence (the distance at which data are autocorrelated) for yields and all soil properties were 24.3-58.5m and 10.5-373m, respectively. Nugget to sill ratios showed that crop yields and soil properties were strongly spatially dependent except bulk density. Majority of the pairs in cross-semivariograms exhibited strong spatial interdependence. The ranges of the spatial dependence varied in plough layer between 54.6m for yield×pH up to 2433m for yield×silt content. Corresponding ranges in subsoil were 24.8m for crop yield×clay content in 2003 and 1404m for yield×bulk density. Kriging maps allowed separating sub-field area with the lowest yield and soil cation exchange capacity, organic carbon content and pH. This area had lighter color on the aerial photograph due to high content of the sand and low content of soil organic carbon. The results will help farmers at identifying sub-field areas for applying localized management practices to improve these soil properties and further spatial studies in larger scale. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  2. Bay of Bengal Exhibits Warming Trend During the Younger Dryas: Implications of AMOC

    NASA Astrophysics Data System (ADS)

    Panmei, Champoungam; Divakar Naidu, Pothuri; Mohtadi, Mahyar

    2017-12-01

    A sharp decline in temperature during the Younger Dryas (YD) preceding the current warmer Holocene is well documented in climate archives from the Northern Hemisphere high latitudes. Although the magnitude of YD cooling varied spatially, the response of YD cooling was well documented in the Atlantic and Pacific Oceans but not in the Indian Ocean. Here we investigate whether the modern remote forcing of tropical Indian Ocean sea surface temperature (SST) by Northern Hemisphere climate changes holds true for events such as the YD. Our SST reconstruction from the western Bay of Bengal exhibits an overall warming of ˜1.8°C during the YD. We further compared our data with other existing Mg/Ca-based SST records from the Northern Indian Ocean and found no significant negative SST anomalies in both the Arabian Sea and the Bay of Bengal compared to pre- and post-YD, suggesting that no apparent cooling occurred during the YD in the Northern Indian Ocean. In contrast, most part of the YD exhibits positive SST anomalies in the Northern Indian Ocean that coincide with the slowdown of the Atlantic Meridional Overturning Circulation during this period.

  3. Reduced brain resting-state network specificity in infants compared with adults.

    PubMed

    Wylie, Korey P; Rojas, Donald C; Ross, Randal G; Hunter, Sharon K; Maharajh, Keeran; Cornier, Marc-Andre; Tregellas, Jason R

    2014-01-01

    Infant resting-state networks do not exhibit the same connectivity patterns as those of young children and adults. Current theories of brain development emphasize developmental progression in regional and network specialization. We compared infant and adult functional connectivity, predicting that infants would exhibit less regional specificity and greater internetwork communication compared with adults. Functional magnetic resonance imaging at rest was acquired in 12 healthy, term infants and 17 adults. Resting-state networks were extracted, using independent components analysis, and the resulting components were then compared between the adult and infant groups. Adults exhibited stronger connectivity in the posterior cingulate cortex node of the default mode network, but infants had higher connectivity in medial prefrontal cortex/anterior cingulate cortex than adults. Adult connectivity was typically higher than infant connectivity within structures previously associated with the various networks, whereas infant connectivity was frequently higher outside of these structures. Internetwork communication was significantly higher in infants than in adults. We interpret these findings as consistent with evidence suggesting that resting-state network development is associated with increasing spatial specificity, possibly reflecting the corresponding functional specialization of regions and their interconnections through experience.

  4. Two (or three) is one too many: testing the flexibility of contextual cueing with multiple target locations.

    PubMed

    Zellin, Martina; Conci, Markus; von Mühlenen, Adrian; Müller, Hermann J

    2011-10-01

    Visual search for a target object is facilitated when the object is repeatedly presented within an invariant context of surrounding items ("contextual cueing"; Chun & Jiang, Cognitive Psychology, 36, 28-71, 1998). The present study investigated whether such invariant contexts can cue more than one target location. In a series of three experiments, we showed that contextual cueing is significantly reduced when invariant contexts are paired with two rather than one possible target location, whereas no contextual cueing occurs with three distinct target locations. Closer data inspection revealed that one "dominant" target always exhibited substantially more contextual cueing than did the other, "minor" target(s), which caused negative contextual-cueing effects. However, minor targets could benefit from the invariant context when they were spatially close to the dominant target. In sum, our experiments suggest that contextual cueing can guide visual attention to a spatially limited region of the display, only enhancing the detection of targets presented inside that region.

  5. 3D Printing of Liquid Crystal Elastomeric Actuators with Spatially Programed Nematic Order.

    PubMed

    Kotikian, Arda; Truby, Ryan L; Boley, John William; White, Timothy J; Lewis, Jennifer A

    2018-03-01

    Liquid crystal elastomers (LCEs) are soft materials capable of large, reversible shape changes, which may find potential application as artificial muscles, soft robots, and dynamic functional architectures. Here, the design and additive manufacturing of LCE actuators (LCEAs) with spatially programed nematic order that exhibit large, reversible, and repeatable contraction with high specific work capacity are reported. First, a photopolymerizable, solvent-free, main-chain LCE ink is created via aza-Michael addition with the appropriate viscoelastic properties for 3D printing. Next, high operating temperature direct ink writing of LCE inks is used to align their mesogen domains along the direction of the print path. To demonstrate the power of this additive manufacturing approach, shape-morphing LCEA architectures are fabricated, which undergo reversible planar-to-3D and 3D-to-3D' transformations on demand, that can lift significantly more weight than other LCEAs reported to date. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Don't wait to incubate: immediate versus delayed incubation in divergent thinking.

    PubMed

    Gilhooly, Kenneth J; Georgiou, George J; Garrison, Jane; Reston, Jon D; Sirota, Miroslav

    2012-08-01

    Previous evidence for the effectiveness of immediate incubation in divergent creative tasks has been weak, because earlier studies exhibited a range of methodological problems. This issue is theoretically important, as a demonstration of the effects of immediate incubation would strengthen the case for the involvement of unconscious work in incubation effects. For the present experiment, we used a creative divergent-thinking task (alternative uses) in which separate experimental groups had incubation periods that were either delayed or immediate and that consisted of either spatial or verbal tasks. Control groups were tested without incubation periods, and we carried out checks for intermittent conscious work on the target task during the incubation periods. The results showed significant incubation effects that were stronger for immediate than for delayed incubation. Performance was not different between the verbal and spatial incubation conditions, and we found no evidence for intermittent conscious working during the incubation periods. These results support a role for unconscious work in creative divergent thinking, particularly in the case of immediate incubation.

  7. Natural Human Mobility Patterns and Spatial Spread of Infectious Diseases

    NASA Astrophysics Data System (ADS)

    Belik, Vitaly; Geisel, Theo; Brockmann, Dirk

    2011-08-01

    We investigate a model for spatial epidemics explicitly taking into account bidirectional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of the model on regular and complex metapopulation network topologies and show that significant dynamical differences exist to ordinary reaction-diffusion and effective force of infection models. On a lattice we calculate an expression for the velocity of the propagating epidemic front and find that, in contrast to the diffusive systems, our model predicts a saturation of the velocity with an increasing traveling rate. Furthermore, we show that a fully stochastic system exhibits a novel threshold for the attack ratio of an outbreak that is absent in diffusion and force of infection models. These insights not only capture natural features of human mobility relevant for the geographical epidemic spread, they may serve as a starting point for modeling important dynamical processes in human and animal epidemiology, population ecology, biology, and evolution.

  8. Spatio-temporal assessment and seasonal variation of tropospheric ozone in Pakistan during the last decade.

    PubMed

    Noreen, Asma; Khokhar, Muhammad Fahim; Zeb, Naila; Yasmin, Naila; Hakeem, Khalid Rehman

    2018-03-01

    This study uses the tropospheric ozone data derived from combined observations of Ozone Monitoring Instrument/Microwave Limb Sounder instruments by using the tropospheric ozone residual method. The main objective was to study the spatial distribution and temporal evolution in the troposphere ozone columns over Pakistan during the time period of 2004 to 2014. Results showed an overall increase of 3.2 ± 1.1 DU in tropospheric ozone columns over Pakistan. Spatial distribution showed enhanced ozone columns in the Punjab and southern Sindh consistent to high population, urbanization, and extensive anthropogenic activities, and exhibited statistically significant temporal increase. Seasonal variations in tropospheric ozone columns are driven by various factors such as seasonality in UV-B fluxes, seasonality in ozone precursor gases such as NO x and volatile organic compounds (caused by temperature dependent biogenic emission) and agricultural fire activities in Pakistan. A strong correlation of 96% (r = 0.96) was found between fire events and tropospheric ozone columns in Pakistan.

  9. A serosurvey of diseases of free-ranging gray wolves (Canis lupus) in Minnesota

    USGS Publications Warehouse

    Carstensen, Michelle; Giudice, John H.; Hildebrand, Erik C.; Dubey, J. P.; Erb, John; Stark, Dan; Hart, John; Barber-Meyer, Shannon M.; Mech, L. David; Windels, Steve K.; Edwards, Andrew J.

    2017-01-01

    We tested serum samples from 387 free-ranging wolves (Canis lupus) from 2007 to 2013 for exposure to eight canid pathogens to establish baseline data on disease prevalence and spatial distribution in Minnesota's wolf population. We found high exposure to canine adenoviruses 1 and 2 (88% adults, 45% pups), canine parvovirus (82% adults, 24% pups), and Lyme disease (76% adults, 39% pups). Sixty-six percent of adults and 36% of pups exhibited exposure to the protozoan parasite Neospora caninum. Exposure to arboviruses was confirmed, including West Nile virus (37% adults, 18% pups) and eastern equine encephalitis (3% adults). Exposure rates were lower for canine distemper (19% adults, 5% pups) and heartworm (7% adults, 3% pups). Significant spatial trends were observed in wolves exposed to canine parvovirus and Lyme disease. Serologic data do not confirm clinical disease, but better understanding of disease ecology of wolves can provide valuable insight into wildlife population dynamics and improve management of these species.

  10. Asymptotic dynamics of the exceptional Bianchi cosmologies

    NASA Astrophysics Data System (ADS)

    Hewitt, C. G.; Horwood, J. T.; Wainwright, J.

    2003-05-01

    In this paper we give, for the first time, a qualitative description of the asymptotic dynamics of a class of non-tilted spatially homogeneous (SH) cosmologies, the so-called exceptional Bianchi cosmologies, which are of Bianchi type VI$_{-1/9}$. This class is of interest for two reasons. Firstly, it is generic within the class of non-tilted SH cosmologies, being of the same generality as the models of Bianchi types VIII and IX. Secondly, it is the SH limit of a generic class of spatially inhomogeneous $G_{2}$ cosmologies. Using the orthonormal frame formalism and Hubble-normalized variables, we show that the exceptional Bianchi cosmologies differ from the non-exceptional Bianchi cosmologies of type VI$_{h}$ in two significant ways. Firstly, the models exhibit an oscillatory approach to the initial singularity and hence are not asymptotically self-similar. Secondly, at late times, although the models are asymptotically self-similar, the future attractor for the vacuum-dominated models is the so-called Robinson-Trautman SH model instead of the vacuum SH plane wave models.

  11. Is the recall of verbal-spatial information from working memory affected by symptoms of ADHD?

    PubMed

    Caterino, Linda C; Verdi, Michael P

    2012-10-01

    OJECTIVE: The Kulhavy model for text learning using organized spatial displays proposes that learning will be increased when participants view visual images prior to related text. In contrast to previous studies, this study also included students who exhibited symptoms of ADHD. Participants were presented with either a map-text or text-map condition. The map-text condition led to a significantly higher performance than the text-map condition, overall. However, students who endorsed more symptoms of inattention and hyperactivity-impulsivity scored more poorly when asked to recall text facts, text features, and map features and were less able to correctly place map features on a reconstructed map than were students who endorsed fewer symptoms. The results of the study support the Kulhavy model for typical students; however, the benefit of viewing a display prior to text was not seen for students with ADHD symptoms, thus supporting previous studies that have demonstrated that ADHD appears to negatively affect operations that occur in working memory.

  12. A SEROSURVEY OF DISEASES OF FREE-RANGING GRAY WOLVES (CANIS LUPUS) IN MINNESOTA, USA.

    PubMed

    Carstensen, Michelle; Giudice, John H; Hildebrand, Erik C; Dubey, J P; Erb, John; Stark, Dan; Hart, John; Barber-Meyer, Shannon; Mech, L David; Windels, Steve K; Edwards, Andrew J

    2017-07-01

    We tested serum samples from 387 free-ranging wolves ( Canis lupus ) from 2007 to 2013 for exposure to eight canid pathogens to establish baseline data on disease prevalence and spatial distribution in Minnesota's wolf population. We found high exposure to canine adenoviruses 1 and 2 (88% adults, 45% pups), canine parvovirus (82% adults, 24% pups), and Lyme disease (76% adults, 39% pups). Sixty-six percent of adults and 36% of pups exhibited exposure to the protozoan parasite Neospora caninum . Exposure to arboviruses was confirmed, including West Nile virus (37% adults, 18% pups) and eastern equine encephalitis (3% adults). Exposure rates were lower for canine distemper (19% adults, 5% pups) and heartworm (7% adults, 3% pups). Significant spatial trends were observed in wolves exposed to canine parvovirus and Lyme disease. Serologic data do not confirm clinical disease, but better understanding of disease ecology of wolves can provide valuable insight into wildlife population dynamics and improve management of these species.

  13. Long range stress correlations in the inherent structures of liquids at rest

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chowdhury, Sadrul; Abraham, Sneha; Hudson, Toby

    2016-03-28

    Simulation studies of the atomic shear stress in the local potential energy minima (inherent structures) are reported for binary liquid mixtures in 2D and 3D. These inherent structure stresses are fundamental to slow stress relaxation and high viscosity in supercooled liquids. We find that the atomic shear stress in the inherent structures (IS’s) of both liquids at rest exhibits slowly decaying anisotropic correlations. We show that the stress correlations contribute significantly to the variance of the total shear stress of the IS configurations and consider the origins of the anisotropy and spatial extent of the stress correlations.

  14. Design of a Minimum Surface-Effect Three Degree-of-Freedom Micromanipulator

    NASA Technical Reports Server (NTRS)

    Goldfarb, Michael; Speich, John E.

    1997-01-01

    This paper describes the fundamental physical motivations for small-scale minimum surface-effect design, and presents a three degree-of-freedom micromanipulator design that incorporates a minimum surface-effect approach. The primary focus of the design is the split-tube flexure, a unique small-scale revolute joint that exhibits a considerably larger range of motion and significantly better multi-axis revolute joint characteristics than a conventional flexure. The development of this joint enables the implementation of a small-scale spatially-loaded revolute joint-based manipulator with well-behaved kinematic characteristics and without the backlash and stick-slip behavior that would otherwise prevent precision control

  15. Pulse-modulated second harmonic imaging microscope quantitatively demonstrates marked increase of collagen in tumor after chemotherapy

    NASA Astrophysics Data System (ADS)

    Raja, Anju M.; Xu, Shuoyu; Sun, Wanxin; Zhou, Jianbiao; Tai, Dean C. S.; Chen, Chien-Shing; Rajapakse, Jagath C.; So, Peter T. C.; Yu, Hanry

    2010-09-01

    Pulse-modulated second harmonic imaging microscopes (PM-SHIMs) exhibit improved signal-to-noise ratio (SNR) over conventional SHIMs on sensitive imaging and quantification of weak collagen signals inside tissues. We quantify the spatial distribution of sparse collagen inside a xenograft model of human acute myeloid leukemia (AML) tumor specimens treated with a new drug against receptor tyrosine kinase (ABT-869), and observe a significant increase in collagen area percentage, collagen fiber length, fiber width, and fiber number after chemotherapy. This finding reveals new insights into tumor responses to chemotherapy and suggests caution in developing new drugs and therapeutic regimens against cancers.

  16. Spin-dependent transport in antiferromagnetic tunnel junctions

    NASA Astrophysics Data System (ADS)

    Merodio, P.; Kalitsov, A.; Béa, H.; Baltz, V.; Chshiev, M.

    2014-09-01

    We investigate the behaviour of spin transfer torque (STT) and tunnelling magnetoresistance (TMR) in epitaxial antiferromagnetic-based tunnel junctions using tight binding calculations in the framework of the Keldysh formalism. We find that the STT out-of-plane component exhibits a staggered spatial distribution similar to its in-plane component. This behaviour is specific to the use of a tunnel barrier and significantly differs from the out-of-plane torques reported in previous works using a metallic spacer. Additionally, we show that unlike conventional ferromagnetic-based tunnel junctions, the TMR can increase with applied bias and reach values comparable to typical magnetoresistances found for usual spin valves.

  17. Baseline element concentrations in soils and plants, Bull Island, Cape Romain National Wildlife Refuge, South Carolina, U.S.A.

    USGS Publications Warehouse

    Gough, L.P.; Severson, R.C.; Jackson, L.L.

    1994-01-01

    Baseline element concentrations are given for Spanish moss (Tillandsia usneoides), loblolly pine (Pinus taeda), and associated soils. Baseline and variability data for ash, Al, Ba, C, Ca, Cd, Ce, Co, Cr, Cu, Fe, K, La, Li, Mg, Mn, Na, Nb, Nd, Ni, P, Pb, S, Sc, Sr, Th, Ti, V, Y, and Zn are reported; however, not all variables are reported for all media because, in some media, certain elements were below the analytical detection limit. Spatial variation in element concentration among and within 0.5 km grid cells are given for each of the media. In general, only a few elements in Spanish moss showed statistically significant landscape patterns, whereas several elements in loblolly pine and in soils exhibited differences among sampling grids. Significant differences in the concentration of three elements in Spanish moss and eight elements (including total S) in loblolly pine were observed between two sampling dates (November and June); however, the absolute amount of these differences was small. Except for perhaps Ni and Pb concentrations in Spanish moss, element levels in all sample media exhibited ranges that indicate natural rather than anthropogenic additions of trace elements.

  18. Topographic, meteorologic, and canopy controls on the scaling characteristics of the spatial distribution of snow depth fields

    Treesearch

    Ernesto Trujillo; Jorge A. Ramirez; Kelly J. Elder

    2007-01-01

    In this study, LIDAR snow depths, bare ground elevations (topography), and elevations filtered to the top of vegetation (topography + vegetation) in five 1-km2 areas are used to determine whether the spatial distribution of snow depth exhibits scale invariance, and the control that vegetation, topography, and winds exert on such behavior. The one-dimensional and mean...

  19. Soil variability along a nitrogen mineralization and nitrification gradient in a nitrogen-saturated hardwood forest

    Treesearch

    Frank S. Gilliam; Nikki L. Lyttle; Ashley Thomas; Mary Beth Adams

    2005-01-01

    Some N-saturated watersheds of the Fernow Experimental Forest (FEF), West Virginia, exhibit a high degree of spatial heterogeneity in soil N processing. We used soils from four sites at FEF representing a gradient in net N mineralization and nitrification to consider the causes and consequences of such spatial heterogeneity. We collected soils with extremely high vs....

  20. Spatial variation in the climatic predictors of species compositional turnover and endemism.

    PubMed

    Di Virgilio, Giovanni; Laffan, Shawn W; Ebach, Malte C; Chapple, David G

    2014-08-01

    Previous research focusing on broad-scale or geographically invariant species-environment dependencies suggest that temperature-related variables explain more of the variation in reptile distributions than precipitation. However, species-environment relationships may exhibit considerable spatial variation contingent upon the geographic nuances that vary between locations. Broad-scale, geographically invariant analyses may mask this local variation and their findings may not generalize to different locations at local scales. We assess how reptile-climatic relationships change with varying spatial scale, location, and direction. Since the spatial distributions of diversity and endemism hotspots differ for other species groups, we also assess whether reptile species turnover and endemism hotspots are influenced differently by climatic predictors. Using New Zealand reptiles as an example, the variation in species turnover, endemism and turnover in climatic variables was measured using directional moving window analyses, rotated through 360°. Correlations between the species turnover, endemism and climatic turnover results generated by each rotation of the moving window were analysed using multivariate generalized linear models applied at national, regional, and local scales. At national-scale, temperature turnover consistently exhibited the greatest influence on species turnover and endemism, but model predictive capacity was low (typically r (2) = 0.05, P < 0.001). At regional scales the relative influence of temperature and precipitation turnover varied between regions, although model predictive capacity was also generally low. Climatic turnover was considerably more predictive of species turnover and endemism at local scales (e.g., r (2) = 0.65, P < 0.001). While temperature turnover had the greatest effect in one locale (the northern North Island), there was substantial variation in the relative influence of temperature and precipitation predictors in the remaining four locales. Species turnover and endemism hotspots often occurred in different locations. Climatic predictors had a smaller influence on endemism. Our results caution against assuming that variability in temperature will always be most predictive of reptile biodiversity across different spatial scales, locations and directions. The influence of climatic turnover on the species turnover and endemism of other taxa may exhibit similar patterns of spatial variation. Such intricate variation might be discerned more readily if studies at broad scales are complemented by geographically variant, local-scale analyses.

  1. Spatial patterns in the condition index of the wild Pacific oyster Crassostrea gigas in a macrotidal coastal ecosystem: Influence of tidal processes and beyond

    NASA Astrophysics Data System (ADS)

    Gasmi, Sonia; Bernard, Ismaël; Pouvreau, Stéphane; Maurer, Danièle; Schaal, Gauthier; Ganthy, Florian; Cominassi, Louise; Allain, Gwenhael; Sautour, Benoit; David, Valérie

    2017-01-01

    In macrotidal coastal ecosystems, spatial heterogeneity of the water column properties is induced by both oceanic and continental influences. Hydrodynamic processes generate a land-sea gradient of environmental conditions, affecting the biological performances of sedentary organisms. The aim of the present study is to establish an extensive spatial assessment in the reproductive investment of the wild Pacific oyster Crassostrea gigas in Arcachon Bay. This is done by looking for a relationship between the Lawrence and Scott condition index (LSCI) and two tidal processes: the immersion level (IL) and the local oceanic flushing time (LoFt). The LSCI of C. gigas was assessed, just before gamete release, at 68 sampling stations in Arcachon Bay. Oyster performance was overall low and spatially variable. Significant differences in the LSCI were detected between the outer and inner bay. Oyster reefs located toward the mouth of the bay exhibited high LSCI (between 9 and 11), while oyster reefs located in inner bay, especially in south-eastern part around the Eyre River, had low LSCI (below 6). Linear modelling allowed to highlight significant effects of both tidal processes IL and LoFt on the obtained LSCI gradient. IL, LoFt explained 33% of the spatial variability observed on LSCI (IL = 3%; LoFt = 17%; LoFt + IL: 13%), 6% were attributed to the intra-station variation (ISv). Thus, high IL and rapid LoFt favor a better development of somatic-gonadal volume, probably because of longer feeding time and higher supply of food from the ocean by tide flows. Disentangling the effects of IL and LoFt on LSCI allowed to describe the spatial pattern in 61% of variability not explained by both tidal factors. A residual gradient directed southeast-northwest highlighted that others factors, independent from IL and LoFt seems to hamper inner bay oyster reproductive performance. Consequently, investigating on the ecological functioning (Eyre influences), trophic potential and anthropogenic pressures of this zone seem crucial on the understanding of C. gigas reproductive pattern in Arcachon Bay.

  2. Disturbance and density-dependent processes (competition and facilitation) influence the fine-scale genetic structure of a tree species' population.

    PubMed

    Fajardo, Alex; Torres-Díaz, Cristian; Till-Bottraud, Irène

    2016-01-01

    Disturbances, dispersal and biotic interactions are three major drivers of the spatial distribution of genotypes within populations, the last of which has been less studied than the other two. This study aimed to determine the role of competition and facilitation in the degree of conspecific genetic relatedness of nearby individuals of tree populations. It was expected that competition among conspecifics will lead to low relatedness, while facilitation will lead to high relatedness (selection for high relatedness within clusters). The stand structure and spatial genetic structure (SGS) of trees were examined within old-growth and second-growth forests (including multi-stemmed trees at the edge of forests) of Nothofagus pumilio following large-scale fires in Patagonia, Chile. Genetic spatial autocorrelations were computed on a spatially explicit sampling of the forests using five microsatellite loci. As biotic plant interactions occur among immediate neighbours, mean nearest neighbour distance (MNND) among trees was computed as a threshold for distinguishing the effects of disturbances and biotic interactions. All forests exhibited a significant SGS for distances greater than the MNND. The old-growth forest genetic and stand structure indicated gap recolonization from nearby trees (significantly related trees at distances between 4 and 10 m). At distances smaller than the MNND, trees of the second-growth interior forest showed significantly lower relatedness, suggesting a fading of the recolonization structure by competition, whereas the second-growth edge forest showed a positive and highly significant relatedness among trees (higher among stems of a cluster than among stems of different clusters), resulting from facilitation. Biotic interactions are shown to influence the genetic composition of a tree population. However, facilitation can only persist if individuals are related. Thus, the genetic composition in turn influences what type of biotic interactions will take place among immediate neighbours in post-disturbance forests. © The Author 2015. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Visually induced adaptation in three-dimensional organization of primate vestibuloocular reflex

    NASA Technical Reports Server (NTRS)

    Angelaki, D. E.; Hess, B. J.

    1998-01-01

    The adaptive plasticity of the spatial organization of the vestibuloocular reflex (VOR) has been investigated in intact and canal-plugged primates using 2-h exposure to conflicting visual (optokinetic, OKN) and vestibular rotational stimuli about mutually orthogonal axes (generating torsional VOR + vertical OKN, torsional VOR + horizontal OKN, vertical VOR + horizontal OKN, and horizontal VOR + vertical OKN). Adaptation protocols with 0.5-Hz (+/-18 degrees ) head movements about either an earth-vertical or an earth-horizontal axis induced orthogonal response components as high as 40-70% of those required for ideal adaptation. Orthogonal response gains were highest at the adapting frequency with phase leads present at lower and phase lags present at higher frequencies. Furthermore, the time course of adaptation, as well as orthogonal response dynamics were similar and relatively independent of the particular visual/vestibular stimulus combination. Low-frequency (0. 05 Hz, vestibular stimulus: +/-60 degrees ; optokinetic stimulus: +/-180 degrees ) adaptation protocols with head movements about an earth-vertical axis induced smaller orthogonal response components that did not exceed 20-40% of the head velocity stimulus (i.e., approximately 10% of that required for ideal adaptation). At the same frequency, adaptation with head movements about an earth-horizontal axis generated large orthogonal responses that reached values as high as 100-120% of head velocity after 2 h of adaptation (i.e., approximately 40% of ideal adaptation gains). The particular spatial and temporal response characteristics after low-frequency, earth-horizontal axis adaptation in both intact and canal-plugged animals strongly suggests that the orienting (and perhaps translational) but not inertial (velocity storage) components of the primate otolith-ocular system exhibit spatial adaptability. Due to the particular nested arrangement of the visual and vestibular stimuli, the optic flow pattern exhibited a significant component about the third spatial axis (i.e., orthogonal to the axes of rotation of the head and visual surround) at twice the oscillation frequency. Accordingly, the adapted VOR was characterized consistently by a third response component (orthogonal to both the axes of head and optokinetic drum rotation) at twice the oscillation frequency after earth-horizontal but not after earth-vertical axis 0.05-Hz adaptation. This suggests that the otolith-ocular (but not the semicircular canal-ocular) system can adaptively change its spatial organization at frequencies different from those of the head movement.

  4. Early Warning Signals of Ecological Transitions: Methods for Spatial Patterns

    PubMed Central

    Brock, William A.; Carpenter, Stephen R.; Ellison, Aaron M.; Livina, Valerie N.; Seekell, David A.; Scheffer, Marten; van Nes, Egbert H.; Dakos, Vasilis

    2014-01-01

    A number of ecosystems can exhibit abrupt shifts between alternative stable states. Because of their important ecological and economic consequences, recent research has focused on devising early warning signals for anticipating such abrupt ecological transitions. In particular, theoretical studies show that changes in spatial characteristics of the system could provide early warnings of approaching transitions. However, the empirical validation of these indicators lag behind their theoretical developments. Here, we summarize a range of currently available spatial early warning signals, suggest potential null models to interpret their trends, and apply them to three simulated spatial data sets of systems undergoing an abrupt transition. In addition to providing a step-by-step methodology for applying these signals to spatial data sets, we propose a statistical toolbox that may be used to help detect approaching transitions in a wide range of spatial data. We hope that our methodology together with the computer codes will stimulate the application and testing of spatial early warning signals on real spatial data. PMID:24658137

  5. High and low schizotypal female subjects do not differ in spatial memory abilities in a virtual reality task.

    PubMed

    García-Montes, José Manuel; Noguera, Carmen; Alvarez, Dolores; Ruiz, Marina; Cimadevilla Redondo, José Manuel

    2014-01-01

    Schizotypy is a psychological construct related to schizophrenia. The exact relationship between both entities is not clear. In recent years, schizophrenia has been associated with hippocampal abnormalities and spatial memory problems. The aim of this study was to determine possible links between high schizotypy (HS) and low schizotypy (LS) and spatial abilities, using virtual reality tasks. We hypothesised that the HS group would exhibit a lower performance in spatial memory tasks than the LS group. Two groups of female students were formed according to their score on the ESQUIZO-Q-A questionnaire. HS and LS subjects were tested on two different tasks: the Boxes Room task, a spatial memory task sensitive to hippocampal alterations and a spatial recognition task. Data showed that both groups mastered both tasks. Groups differed in personality features but not in spatial performance. These results provide valuable information about the schizotypy-schizophrenia connections. Schizotypal subjects are not impaired on spatial cognition and, accordingly, the schizotypy-schizophrenia relationship is not straightforward.

  6. Depth as an Organizing Force in Pocillopora damicornis: Intra-Reef Genetic Architecture

    PubMed Central

    Gorospe, Kelvin D.; Karl, Stephen A.

    2015-01-01

    Relative to terrestrial plants, and despite similarities in life history characteristics, the potential for corals to exhibit intra-reef local adaptation in the form of genetic differentiation along an environmental gradient has received little attention. The potential for natural selection to act on such small scales is likely increased by the ability of coral larval dispersal and settlement to be influenced by environmental cues. Here, we combine genetic, spatial, and environmental data for a single patch reef in Kāne‘ohe Bay, O‘ahu, Hawai‘i, USA in a landscape genetics framework to uncover environmental drivers of intra-reef genetic structuring. The genetic dataset consists of near-exhaustive sampling (n = 2352) of the coral, Pocillopora damicornis at our study site and six microsatellite genotypes. In addition, three environmental parameters – depth and two depth-independent temperature indices – were collected on a 4 m grid across 85 locations throughout the reef. We use ordinary kriging to spatially interpolate our environmental data and estimate the three environmental parameters for each colony. Partial Mantel tests indicate a significant correlation between genetic relatedness and depth while controlling for space. These results are also supported by multi-model inference. Furthermore, spatial Principle Component Analysis indicates a statistically significant genetic cline along a depth gradient. Binning the genetic dataset based on size-class revealed that the correlation between genetic relatedness and depth was significant for new recruits and increased for larger size classes, suggesting a possible role of larval habitat selection as well as selective mortality in structuring intra-reef genetic diversity. That both pre- and post-recruitment processes may be involved points to the adaptive role of larval habitat selection in increasing adult survival. The conservation importance of uncovering intra-reef patterns of genetic diversity is discussed. PMID:25806798

  7. Protective Effects of 17β-Estradiol on Hippocampal Myelinated Fibers in Ovariectomized Middle-aged Rats.

    PubMed

    Xiao, Qian; Luo, Yanmin; Lv, Fulin; He, Qi; Wu, Hong; Chao, Fenglei; Qiu, Xuan; Zhang, Lei; Gao, Yuan; Huang, Chunxia; Wang, Sanrong; Zhou, Chunni; Zhang, Yi; Jiang, Lin; Tang, Yong

    2018-06-14

    Estrogen replacement therapy (ERT) improves hippocampus-dependent cognition. This study investigated the impact of estrogen on hippocampal volume, CA1 subfield volume and myelinated fibers in the CA1 subfield of middle-aged ovariectomized rats. Ten-month-old bilaterally ovariectomized (OVX) female rats were randomly divided into OVX + E2 and OVX + Veh groups. After four weeks of subcutaneous injection with 17β-estradiol or a placebo, the OVX + E2 rats exhibited significantly short mean escape latency in a spatial learning task than that in the OVX + Veh rats. Using stereological methods, we did not observe significant differences in the volumes of the hippocampus and CA1 subfields between the two groups. However, using stereological methods and electron microscopy techniques, the total length of myelinated fibers and the total volumes of myelinated fibers, myelin sheaths and myelinated axons in the CA1 subfields of OVX + E2 rats were significantly 38.1%, 34.2%, 36.1% and 32.5%, respectively, higher than those in the OVX + Veh rats. After the parameters were calculated according to different diameter ranges, the estrogen replacement-induced remodeling of myelinated fibers in CA1 was mainly manifested in the myelinated fibers with a diameter of <1.0 μm. Therefore, four weeks of continuous E2 replacement improved the spatial learning capabilities of middle-aged ovariectomized rats. The E2 replacement-induced protection of spatial learning abilities might be associated with the beneficial effects of estrogen on myelinated fibers, particularly those with the diameters less than 1.0 μm, in the hippocampal CA1 region of middle-aged ovariectomized rats. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  8. A Note on the Spatio Temporal Variations in the Temperature and Relative Humidity over Akure, Ondo State, Nigeria

    NASA Astrophysics Data System (ADS)

    Eludoyin, A. O.; Akinbode, O. M.; Archibong, E. O.

    2007-07-01

    This study was carried out in one of the Administrative State Capitals in the southwestern part of Nigeria. Its aim is to serve as a baseline data for highlighting the effect of spatial distribution of settlements, population, and socioeconomic activities on urban air temperature and relative humidity. The main objective of the study is to assess the impact of urban growth on the microclimate of the administrative city. Temperature and relative humidity data from 1992 to 2001 were obtained from the three existing meteorological stations in Akure, the Administrative Capital of Ondo State, Nigeria, namely the Federal Ministry of Aviation, Akure Airport station (FMA), Federal University of Technology, Akure (FUTA) and the Federal School of Agriculture (SOA). Air temperature and relative humidity measurements along primary roads and in the built up areas were obtained from seventeen stations, using sling psychrometer. The data were subsequently analysed for spatial and temporal variations. The results obtained indicated that while the maximum, average and minimum temperatures showed significant annual variations, the spatial variations among the existing meteorological stations were not significant. The city is characterized by increasing annual mean temperatures whose maximum was significantly higher than that of Ondo town — another important town within the state. The annual mean temperatures ranged between 26.2°C and 30.4°C. Minimum and maximum temperatures varied from 12.3°C to 26°C and 22.5°C to 39.6°C, respectively while the relative humidity ranged between 27.5% and 98.2%. Urban `heat island' intensity was exhibited around central business district of the Oba market. 2007 American Institute of Physics

  9. Nucleation of cracks in sedimentary rocks under non-uniform loading: insights from simultaneous X-ray and neutron imaging

    NASA Astrophysics Data System (ADS)

    LaManna, J.; Syed, A.; Tanino, Y.; Jacobson, D. L.

    2016-12-01

    Evapotranspiration (ET) is one of the most important fluxes in the terrestrial ecosystem, and play a vital role in regulating atmosphere-hydrosphere-biosphere interaction. Several studies have suggested that global ET has significantly increased in the past several decades, and that such increase has exhibited big spatial variability, but there are few detailed studies on the spatio-temporal change in ET over China. Combining remote-sensing and ground-based observations with a machine learning approach (model tree ensemble, MTE), this study investigate the spatiotemporal variation in ET in China during 1982 and 2015. Our results showed that mean annual ET in China is 552±14mm year-1, which is within range of estimates by previous studies (from 430 mm year-1 to 555 mm year-1). ET spatially decreases from southeast to northwest, with highest value appeared in humidity regions (more than 1400 mm year-1) and lowest value in arid regions (less than 200 mm year-1). Over the past three decades, ET in China significantly increased by 1.07 mm year-2 with remarkable spatial heterogeneity. The largest increase in ET appears in the eastern periphery of SiChuan Basin, which may be related to increase in temperature, solar radiation as well as enhancing vegetation productivity. Only 20% of study area show decrease in ET, which is mainly located in parts of the southeast, southwest and northeast of China. The regional decrease in ET is likely to be contributed by decrease in solar radiation and relative humidity. Although our finding of the significant increase in China's ET at the country scale is supported by five different ET products, there are still less agreement on the change in ET at the regional scale among different ET products.

  10. Automated sub-cortical brain structure segmentation combining spatial and deep convolutional features.

    PubMed

    Kushibar, Kaisar; Valverde, Sergi; González-Villà, Sandra; Bernal, Jose; Cabezas, Mariano; Oliver, Arnau; Lladó, Xavier

    2018-06-15

    Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time as morphological changes in these structures are related to different neurodegenerative disorders. However, manual segmentation of these structures can be tedious and prone to variability, highlighting the need for robust automated segmentation methods. In this paper, we present a novel convolutional neural network based approach for accurate segmentation of the sub-cortical brain structures that combines both convolutional and prior spatial features for improving the segmentation accuracy. In order to increase the accuracy of the automated segmentation, we propose to train the network using a restricted sample selection to force the network to learn the most difficult parts of the structures. We evaluate the accuracy of the proposed method on the public MICCAI 2012 challenge and IBSR 18 datasets, comparing it with different traditional and deep learning state-of-the-art methods. On the MICCAI 2012 dataset, our method shows an excellent performance comparable to the best participant strategy on the challenge, while performing significantly better than state-of-the-art techniques such as FreeSurfer and FIRST. On the IBSR 18 dataset, our method also exhibits a significant increase in the performance with respect to not only FreeSurfer and FIRST, but also comparable or better results than other recent deep learning approaches. Moreover, our experiments show that both the addition of the spatial priors and the restricted sampling strategy have a significant effect on the accuracy of the proposed method. In order to encourage the reproducibility and the use of the proposed method, a public version of our approach is available to download for the neuroimaging community. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  11. Spatial and seasonal dynamics of brook trout populations inhabiting a central Appalachian watershed

    USGS Publications Warehouse

    Petty, J.T.; Lamothe, P.J.; Mazik, P.M.

    2005-01-01

    We quantified the watershed-scale spatial population dynamics of brook trout Salvelinus fontinalis in the Second Fork, a third-order tributary of Shavers Fork in eastern West Virginia. We used visual surveys, electrofishing, and mark-recapture techniques to quantify brook trout spawning intensity, population density, size structure, and demographic rates (apparent survival and immigration) throughout the watershed. Our analyses produced the following results. Spawning by brook trout was concentrated in streams with small basin areas (i.e., segments draining less than 3 km2), relatively high alkalinity (>10 mg CaCO3/L), and high amounts of instream cover. The spatial distribution of juvenile and small-adult brook trout within the watershed was relatively stable and was significantly correlated with spawning intensity. However, no such relationship was observed for large adults, which exhibited highly variable distribution patterns related to seasonally important habitat features, including instream cover, stream depth and width, and riparian canopy cover. Brook trout survival and immigration rates varied seasonally, spatially, and among size-classes. Differential survival and immigration tended to concentrate juveniles and small adults in small, alkaline streams, whereas dispersal tended to redistribute large adults at the watershed scale. Our results suggest that spatial and temporal variations in spawning, survival, and movement interact to determine the distribution, abundance, and size structure of brook trout populations at a watershed scale. These results underscore the importance of small tributaries for the persistence of brook trout in this watershed and the need to consider watershed-scale processes when designing management plans for Appalachian brook trout populations. ?? Copyright by the American Fisheries Society 2005.

  12. Asynchronous response of tropical forest leaf phenology to seasonal and el Niño-driven drought.

    PubMed

    Pau, Stephanie; Okin, Gregory S; Gillespie, Thomas W

    2010-06-25

    The Hawaiian Islands are an ideal location to study the response of tropical forests to climate variability because of their extreme isolation in the middle of the Pacific, which makes them especially sensitive to El Niño-Southern Oscillation (ENSO). Most research examining the response of tropical forests to drought or El Niño have focused on rainforests, however, tropical dry forests cover a large area of the tropics and may respond very differently than rainforests. We use satellite-derived Normalized Difference Vegetation Index (NDVI) from February 2000-February 2009 to show that rainforests and dry forests in the Hawaiian Islands exhibit asynchronous responses in leaf phenology to seasonal and El Niño-driven drought. Dry forest NDVI was more tightly coupled with precipitation compared to rainforest NDVI. Rainforest cloud frequency was negatively correlated with the degree of asynchronicity (Delta(NDVI)) between forest types, most strongly at a 1-month lag. Rainforest green-up and dry forest brown-down was particularly apparent during the 2002-003 El Niño. The spatial pattern of NDVI response to the NINO 3.4 Sea Surface Temperature (SST) index during 2002-2003 showed that the leeward side exhibited significant negative correlations to increased SSTs, whereas the windward side exhibited significant positive correlations to increased SSTs, most evident at an 8 to 9-month lag. This study demonstrates that different tropical forest types exhibit asynchronous responses to seasonal and El Niño-driven drought, and suggests that mechanisms controlling dry forest leaf phenology are related to water-limitation, whereas rainforests are more light-limited.

  13. Asynchronous Response of Tropical Forest Leaf Phenology to Seasonal and El Niño-Driven Drought

    PubMed Central

    Pau, Stephanie; Okin, Gregory S.; Gillespie, Thomas W.

    2010-01-01

    The Hawaiian Islands are an ideal location to study the response of tropical forests to climate variability because of their extreme isolation in the middle of the Pacific, which makes them especially sensitive to El Niño-Southern Oscillation (ENSO). Most research examining the response of tropical forests to drought or El Niño have focused on rainforests, however, tropical dry forests cover a large area of the tropics and may respond very differently than rainforests. We use satellite-derived Normalized Difference Vegetation Index (NDVI) from February 2000-February 2009 to show that rainforests and dry forests in the Hawaiian Islands exhibit asynchronous responses in leaf phenology to seasonal and El Niño-driven drought. Dry forest NDVI was more tightly coupled with precipitation compared to rainforest NDVI. Rainforest cloud frequency was negatively correlated with the degree of asynchronicity (ΔNDVI) between forest types, most strongly at a 1-month lag. Rainforest green-up and dry forest brown-down was particularly apparent during the 2002–003 El Niño. The spatial pattern of NDVI response to the NINO 3.4 Sea Surface Temperature (SST) index during 2002–2003 showed that the leeward side exhibited significant negative correlations to increased SSTs, whereas the windward side exhibited significant positive correlations to increased SSTs, most evident at an 8 to 9-month lag. This study demonstrates that different tropical forest types exhibit asynchronous responses to seasonal and El Niño-driven drought, and suggests that mechanisms controlling dry forest leaf phenology are related to water-limitation, whereas rainforests are more light-limited. PMID:20593034

  14. Spatial and temporal heterogeneity of infectious hematopoietic necrosis virus in Pacific Northwest salmonids

    USGS Publications Warehouse

    Breyta, Rachel; Black, Allison; Kaufman, John; Kurath, Gael

    2016-01-01

    The aquatic rhaboviral pathogen infectious hematopoietic necrosis virus (IHNV) causes acute disease in juvenile fish of a number of populations of Pacific salmonid species. Heavily managed in both marine and freshwater environments, these fish species are cultured during the juvenile stage in freshwater conservation hatcheries, where IHNV is one of the top three infectious diseases that cause serious morbidity and mortality. Therefore, a comprehensive study of viral genetic surveillance data representing 2590 field isolates collected between 1958 and 2014 was conducted to determine the spatial and temporal patterns of IHNV in the Pacific Northwest of the contiguous United States. Prevalence of infection varied over time, fluctuating over a rough 5–7 year cycle. The genetic analysis revealed numerous subgroups of IHNV, each of which exhibited spatial heterogeneity. Within all subgroups, dominant genetic types were apparent, though the temporal patterns of emergence of these types varied among subgroups. Finally, the affinity or fidelity of subgroups to specific host species also varied, where UC subgroup viruses exhibited a more generalist profile and all other subgroups exhibited a specialist profile. These complex patterns are likely synergistically driven by numerous ecological, pathobiological, and anthropogenic factors. Since only a few anthropogenic factors are candidates for managed intervention aimed at improving the health of threatened or endangered salmonid fish populations, determining the relative impact of these factors is a high priority for future studies.

  15. Face perception in women with Turner syndrome and its underlying factors.

    PubMed

    Anaki, David; Zadikov Mor, Tal; Gepstein, Vardit; Hochberg, Ze'ev

    2016-09-01

    Turner syndrome (TS) is a chromosomal condition that affects development in females. It is characterized by short stature, ovarian failure and other congenital malformations, due to a partial or complete absence of the sex chromosome. Women with TS frequently suffer from various physical and hormonal dysfunctions, along with impairments in visual-spatial processing and social cognition difficulties. Previous research has also shown difficulties in face and emotion perception. In the current study we examined two questions: First, whether women with TS, that are impaired in face perception, also suffer from deficits in face-specific processes. The second question was whether these face impairments in TS are related to visual-spatial perceptual dysfunctions exhibited by TS individuals, or to impaired social cognition skills. Twenty-six women with TS and 26 control participants were tested on various cognitive and psychological tests to assess visual-spatial perception, face and facial expression perception, and social cognition skills. Results show that women with TS were less accurate in face perception and facial expression processing, yet they exhibited normal face-specific processes (configural and holistic processing). They also showed difficulties in spatial perception and social cognition capacities. Additional analyses revealed that their face perception impairments were related to their deficits in visual-spatial processing. Thus, our results do not support the claim that the impairments in face processing observed in TS are related to difficulties in social cognition. Rather, our data point to the possibility that face perception difficulties in TS stem from visual-spatial impairments and may not be specific to faces. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Graphene Oxide: A Perfect Material for Spatial Light Modulation Based on Plasma Channels

    PubMed Central

    Tan, Chao; Wu, Xinghua; Wang, Qinkai; Tang, Pinghua; Shi, Xiaohui; Zhan, Shiping; Xi, Zaifang; Fu, Xiquan

    2017-01-01

    The graphene oxide (GO) is successfully prepared from a purified natural graphite through a pressurized oxidation method. We experimentally demonstrate that GO as an optical media can be used for spatial light modulation based on plasma channels induced by femtosecond pulses. The modulated beam exhibits good propagation properties in free space. It is easy to realize the spatial modulation on the probe beam at a high concentration of GO dispersion solutions, high power and smaller pulse width of the pump beam. We also find that the spatial modulation on the probe beam can be conveniently adjusted through the power and pulse width of pump lasers, dispersion solution concentration. PMID:28772712

  17. Dyscalculia and vestibular function.

    PubMed

    Smith, P F

    2012-10-01

    A few studies in humans suggest that changes in stimulation of the balance organs of the inner ear (the 'vestibular system') can disrupt numerical cognition, resulting in 'dyscalculia', the inability to manipulate numbers. Many studies have also demonstrated that patients with vestibular dysfunction exhibit deficits in spatial memory. It is suggested that there may be a connection between spatial memory deficits resulting from vestibular dysfunction and the occurrence of dyscalculia, given the evidence that numerosity is coupled to the processing of spatial information (e.g., the 'spatial numerical association of response codes ('SNARC') effect'). The evidence supporting this hypothesis is summarised and potential experiments to test it are proposed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. Effects of gender, imagery ability, and sports practice on the performance of a mental rotation task.

    PubMed

    Habacha, Hamdi; Molinaro, Corinne; Dosseville, Fabrice

    2014-01-01

    Mental rotation is one of the main spatial abilities necessary in the spatial transformation of mental images and the manipulation of spatial parameters. Researchers have shown that mental rotation abilities differ between populations depending on several variables. This study uses a mental rotation task to investigate effects of several factors on the spatial abilities of 277 volunteers. The results demonstrate that high and low imagers performed equally well on this tasks. Athletes outperformed nonathletes regardless of their discipline, and athletes with greater expertise outperformed those with less experience. The results replicate the previously reported finding that men exhibit better spatial abilities than women. However, with high amounts of practice, the women in the current study were able to perform as well as men.

  19. Temporal and spatial characteristics of annual and seasonal rainfall in Malawi

    NASA Astrophysics Data System (ADS)

    Ngongondo, Cosmo; Xu, Chong-Yu; Gottschalk, Lars; Tallaksen, Lena M.; Alemaw, Berhanu

    2010-05-01

    An understanding of the temporal and spatial characteristics of rainfall is central to water resources planning and management. However, such information is often limited in many developing countries like Malawi. In an effort to bridge the information gap, this study examined the temporal and spatial charecteristics of rainfall in Malawi. Rainfall readings from 42 stations across Malawi from 1960 to 2006 were analysed at monthly, annual and seasonal scales. The Malawian rainfall season lasts from November to April. The data were firstly subjected to quality checks through the cumulative deviations test and the Standard Normal Homogeinity Test (SNHT). Monthly distribution in a typical year, called heterogeneity, was investigated using the Precipitation Concentration Index (PCI). Further, normalized precipitation anomaly series of annual rainfall series (AR) and the PCI (APCI) were used to test for interannual rainfall variability. Spatial variability was characterised by fitting the Spatial Correlation function (SCF). The nonparametric Mann-Kendall statistic was used to investigate the temporal trends of the various rainfall variables. The results showed that 40 of the stations passed both data quality tests. For the two stations that failed, the data were adjusted using nearby stations. Annual and seasonal rainfall were found to be characterised by high spatial variation. The country mean annual rainfall was 1095 mm with mean interannual variability of 26%. The highland areas to the north and southeast of the country exhibited the highest rainfall and lowest interannual variability. Lowest rainfall coupled with high interannual variability was found in the Lower Shire basin, in the southern part of Malawi. This simillarity is the pattern of annual and seasonal rainfall should be expected because all stations had over 90% of their observed annual rainfall in the six month period between November and April. Monthly rainfall was found to be highly variable both temporally and spatially. None of the stations have stable monthly rainfall regimes (mean PCI of less than 10). Stations with the highest mean rainfall were found to have a lower interannual variability. The rainfall stations showed low spatial correlations for annual, monthly as well as seasonal timescales indicating that the data may not be suitable for spatial interpolation. However, some structure (i.e. lower correlation with distance) could be observed when aggregating the data at 50 mile intervals. The annual and seasonal rainfall series were dominated by negative trends. The spatial distribution of the trends can be described as heterogeneous, although most of the stations in the southern region have negative trends. At the monthly timescale, 37 of the stations show a negative trend with four of the stations, all in the south, showing significant negative trends. On the other hand, only 5 stations show positive trends with only one significant trend in the south. Keywords: Malawi, rainfall trends, spatial variation

  20. Analysis of satellite precipitation over East Africa during last decades

    NASA Astrophysics Data System (ADS)

    Cattani, Elsa; Wenhaji Ndomeni, Claudine; Merino, Andrés; Levizzani, Vincenzo

    2016-04-01

    Daily accumulated precipitation time series from satellite retrieval algorithms (e.g., ARC2 and TAMSAT) are exploited to extract the spatial and temporal variability of East Africa (EA - 5°S-20°N, 28°E-52°E) precipitation during last decades (1983-2013). The Empirical Orthogonal Function (EOF) analysis is applied to precipitation time series to investigate the spatial and temporal variability in particular for October-November-December referred to as the short rain season. Moreover, the connection among EA's precipitation, sea surface temperature, and soil moisture is analyzed through the correlation with the dominant EOF modes of variability. Preliminary results concern the first two EOF's modes for the ARC2 data set. EOF1 is characterized by an inter-annual variability and a positive correlation between precipitation and El Niño, positive Indian Ocean Dipole mode, and soil moisture, while EOF2 shows a dipole structure of spatial variability associated with a longer scale temporal variability. This second dominant mode is mostly linked to sea surface temperature variations in the North Atlantic Ocean. Further analyses are carried out by computing the time series of the joint CCI/CLIVAR/JCOMM Expert Team on Climate Change Detection and Indices (ETCCDI, http://etccdi.pacificclimate.org/index.shtml), i.e. RX1day, RX5day, CDD, CDD, CWD, SDII, PRCPTOT, R10, R20. The purpose is to identify the occurrenes of extreme events (droughts and floods) and extract precipitation temporal variation by trend analysis (Mann-Kendall technique). Results for the ARC2 data set demonstrate the existence of a dipole spatial pattern in the linear trend of the time series of PRCPTOT (annual precipitation considering days with a rain rate > 1 mm) and SDII (average precipitation on wet days over a year). A negative trend is mainly present over West Ethiopia and Sudan, whereas a positive trend is exhibited over East Ethiopia and Somalia. CDD (maximum number of consecutive dry days) and CWD (maximum number of consecutive wet days) time series do not exhibit a similar behavior and trends are generally weaker with a lower significance level with respect to PRCPTOT and SDII.

  1. Strongyloides stercoralis and hookworm co-infection: spatial distribution and determinants in Preah Vihear Province, Cambodia.

    PubMed

    Forrer, Armelle; Khieu, Virak; Schär, Fabian; Vounatsou, Penelope; Chammartin, Frédérique; Marti, Hanspeter; Muth, Sinuon; Odermatt, Peter

    2018-01-12

    Strongyloides stercoralis and hookworm are two soil-transmitted helminths (STH) that are highly prevalent in Cambodia. Strongyloides stercoralis causes long-lasting infections and significant morbidity but is largely neglected, while hookworm causes the highest public health burden among STH. The two parasites have the same infection route, i.e. skin penetration. The extent of co-distribution, which could result in potential high co-morbidities, is unknown in highly endemic settings like Cambodia. The aim of this study was to predict the spatial distribution of S. stercoralis-hookworm co-infection risk and to investigate determinants of co-infection in Preah Vihear Province, North Cambodia. A cross-sectional survey was conducted in 2010 in 60 villages of Preah Vihear Province. Diagnosis was performed on two stool samples, using combined Baermann technique and Koga agar culture plate for S. stercoralis and Kato-Katz technique for hookworm. Bayesian multinomial geostatistical models were used to assess demographic, socioeconomic, and behavioural determinants of S. stercoralis-hookworm co-infection and to predict co-infection risk at non-surveyed locations. Of the 2576 participants included in the study, 48.6% and 49.0% were infected with S. stercoralis and hookworm, respectively; 43.8% of the cases were co-infections. Females, preschool aged children, adults aged 19-49 years, and participants who reported regularly defecating in toilets, systematically boiling drinking water and having been treated with anthelmintic drugs had lower odds of co-infection. While S. stercoralis infection risk did not appear to be spatially structured, hookworm mono-infection and co-infection exhibited spatial correlation at about 20 km. Co-infection risk was positively associated with longer walking distances to a health centre and exhibited a small clustering tendency. The association was only partly explained by climatic variables, suggesting a role for underlying factors, such as living conditions and remoteness. Both parasites were ubiquitous in the province, with co-infections accounting for almost half of all cases. The high prevalence of S. stercoralis calls for control measures. Despite several years of school-based de-worming programmes, hookworm infection levels remain high. Mebendazole efficacy, as well as coverage of and compliance to STH control programmes should be investigated.

  2. Two-Term Asymptotic Approximation of a Cardiac Restitution Curve*

    PubMed Central

    Cain, John W.; Schaeffer, David G.

    2007-01-01

    If spatial extent is neglected, ionic models of cardiac cells consist of systems of ordinary differential equations (ODEs) which have the property of excitability, i.e., a brief stimulus produces a prolonged evolution (called an action potential in the cardiac context) before the eventual return to equilibrium. Under repeated stimulation, or pacing, cardiac tissue exhibits electrical restitution: the steady-state action potential duration (APD) at a given pacing period B shortens as B is decreased. Independent of ionic models, restitution is often modeled phenomenologically by a one-dimensional mapping of the form APDnext = f(B – APDprevious). Under some circumstances, a restitution function f can be derived as an asymptotic approximation to the behavior of an ionic model. In this paper, extending previous work, we derive the next term in such an asymptotic approximation for a particular ionic model consisting of two ODEs. The two-term approximation exhibits excellent quantitative agreement with the actual restitution curve, whereas the leading-order approximation significantly underestimates actual APD values. PMID:18080006

  3. Demonstration of Hadoop-GIS: A Spatial Data Warehousing System Over MapReduce.

    PubMed

    Aji, Ablimit; Sun, Xiling; Vo, Hoang; Liu, Qioaling; Lee, Rubao; Zhang, Xiaodong; Saltz, Joel; Wang, Fusheng

    2013-11-01

    The proliferation of GPS-enabled devices, and the rapid improvement of scientific instruments have resulted in massive amounts of spatial data in the last decade. Support of high performance spatial queries on large volumes data has become increasingly important in numerous fields, which requires a scalable and efficient spatial data warehousing solution as existing approaches exhibit scalability limitations and efficiency bottlenecks for large scale spatial applications. In this demonstration, we present Hadoop-GIS - a scalable and high performance spatial query system over MapReduce. Hadoop-GIS provides an efficient spatial query engine to process spatial queries, data and space based partitioning, and query pipelines that parallelize queries implicitly on MapReduce. Hadoop-GIS also provides an expressive, SQL-like spatial query language for workload specification. We will demonstrate how spatial queries are expressed in spatially extended SQL queries, and submitted through a command line/web interface for execution. Parallel to our system demonstration, we explain the system architecture and details on how queries are translated to MapReduce operators, optimized, and executed on Hadoop. In addition, we will showcase how the system can be used to support two representative real world use cases: large scale pathology analytical imaging, and geo-spatial data warehousing.

  4. Dissipative structures induced by spin-transfer torques in nanopillars

    NASA Astrophysics Data System (ADS)

    León, Alejandro O.; Clerc, Marcel G.; Coulibaly, Saliya

    2014-02-01

    Macroscopic magnetic systems subjected to external forcing exhibit complex spatiotemporal behaviors as result of dissipative self-organization. Pattern formation from a uniform magnetization state, induced by the combination of a spin-polarized current and an external magnetic field, is studied for spin-transfer nano-oscillator devices. The system is described in the continuous limit by the Landau-Lifshitz-Gilbert equation. The bifurcation diagram of the quintessence parallel state, as a function of the external field and current, is elucidated. We have shown analytically that this state exhibits a spatial supercritical quintic bifurcation, which generates in two spatial dimensions a family of stationary stripes, squares, and superlattice states. Analytically, we have characterized their respective stabilities and bifurcations, which are controlled by a single dimensionless parameter. This scenario is confirmed numerically.

  5. Operationalizing the social-ecological systems framework to assess sustainability.

    PubMed

    Leslie, Heather M; Basurto, Xavier; Nenadovic, Mateja; Sievanen, Leila; Cavanaugh, Kyle C; Cota-Nieto, Juan José; Erisman, Brad E; Finkbeiner, Elena; Hinojosa-Arango, Gustavo; Moreno-Báez, Marcia; Nagavarapu, Sriniketh; Reddy, Sheila M W; Sánchez-Rodríguez, Alexandra; Siegel, Katherine; Ulibarria-Valenzuela, José Juan; Weaver, Amy Hudson; Aburto-Oropeza, Octavio

    2015-05-12

    Environmental governance is more effective when the scales of ecological processes are well matched with the human institutions charged with managing human-environment interactions. The social-ecological systems (SESs) framework provides guidance on how to assess the social and ecological dimensions that contribute to sustainable resource use and management, but rarely if ever has been operationalized for multiple localities in a spatially explicit, quantitative manner. Here, we use the case of small-scale fisheries in Baja California Sur, Mexico, to identify distinct SES regions and test key aspects of coupled SESs theory. Regions that exhibit greater potential for social-ecological sustainability in one dimension do not necessarily exhibit it in others, highlighting the importance of integrative, coupled system analyses when implementing spatial planning and other ecosystem-based strategies.

  6. VEP contrast sensitivity responses reveal reduced functional segregation of mid and high filters of visual channels in autism.

    PubMed

    Jemel, Boutheina; Mimeault, Daniel; Saint-Amour, Dave; Hosein, Anthony; Mottron, Laurent

    2010-06-01

    Despite the vast amount of behavioral data showing a pronounced tendency in individuals with autism spectrum disorder (ASD) to process fine visual details, much less is known about the neurophysiological characteristics of spatial vision in ASD. Here, we address this issue by assessing the contrast sensitivity response properties of the early visual-evoked potentials (VEPs) to sine-wave gratings of low, medium and high spatial frequencies in adults with ASD and in an age- and IQ-matched control group. Our results show that while VEP contrast responses to low and high spatial frequency gratings did not differ between ASD and controls, early VEPs to mid spatial frequency gratings exhibited similar response characteristics as those to high spatial frequency gratings in ASD. Our findings show evidence for an altered functional segregation of early visual channels, especially those responsible for processing mid- and high-frequency spatial scales.

  7. Pressure-gradient-driven nearshore circulation on a beach influenced by a large inlet-tidal shoal system

    USGS Publications Warehouse

    Shi, F.; Hanes, D.M.; Kirby, J.T.; Erikson, L.; Barnard, P.; Eshleman, J.

    2011-01-01

    The nearshore circulation induced by a focused pattern of surface gravity waves is studied at a beach adjacent to a major inlet with a large ebb tidal shoal. Using a coupled wave and wave-averaged nearshore circulation model, it is found that the nearshore circulation is significantly affected by the heterogeneous wave patterns caused by wave refraction over the ebb tidal shoal. The model is used to predict waves and currents during field experiments conducted near the mouth of San Francisco Bay and nearby Ocean Beach. The field measurements indicate strong spatial variations in current magnitude and direction and in wave height and direction along Ocean Beach and across the ebb tidal shoal. Numerical simulations suggest that wave refraction over the ebb tidal shoal causes wave focusing toward a narrow region at Ocean Beach. Due to the resulting spatial variation in nearshore wave height, wave-induced setup exhibits a strong alongshore nonuniformity, resulting in a dramatic change in the pressure field compared to a simulation with only tidal forcing. The analysis of momentum balances inside the surf zone shows that, under wave conditions with intensive wave focusing, the alongshore pressure gradient associated with alongshore nonuniform wave setup can be a dominant force driving circulation, inducing heterogeneous alongshore currents. Pressure-gradient- forced alongshore currents can exhibit flow reversals and flow convergence or divergence, in contrast to the uniform alongshore currents typically caused by tides or homogeneous waves.

  8. Microscale Characterization of the Viscoelastic Properties of Hydrogel Biomaterials using Dual-Mode Ultrasound Elastography

    PubMed Central

    Hong, Xiaowei; Stegemann, Jan P.; Deng, Cheri X.

    2016-01-01

    Characterization of the microscale mechanical properties of biomaterials is a key challenge in the field of mechanobiology. Dual-mode ultrasound elastography (DUE) uses high frequency focused ultrasound to induce compression in a sample, combined with interleaved ultrasound imaging to measure the resulting deformation. This technique can be used to non-invasively perform creep testing on hydrogel biomaterials to characterize their viscoelastic properties. DUE was applied to a range of hydrogel constructs consisting of either hydroxyapatite (HA)-doped agarose, HA-collagen, HA-fibrin, or preosteoblast-seeded collagen constructs. DUE provided spatial and temporal mapping of local and bulk displacements and strains at high resolution. Hydrogel materials exhibited characteristic creep behavior, and the maximum strain and residual strain were both material- and concentration-dependent. Burger’s viscoelastic model was used to extract characteristic parameters describing material behavior. Increased protein concentration resulted in greater stiffness and viscosity, but did not affect the viscoelastic time constant of acellular constructs. Collagen constructs exhibited significantly higher modulus and viscosity than fibrin constructs. Cell-seeded collagen constructs became stiffer with altered mechanical behavior as they developed over time. Importantly, DUE also provides insight into the spatial variation of viscoelastic properties at sub-millimeter resolution, allowing interrogation of the interior of constructs. DUE presents a novel technique for non-invasively characterizing hydrogel materials at the microscale, and therefore may have unique utility in the study of mechanobiology and the characterization of hydrogel biomaterials. PMID:26928595

  9. Spatial characterization, risk assessment, and statistical source identification of the dissolved trace elements in the Ganjiang River-feeding tributary of the Poyang Lake, China.

    PubMed

    Zhang, Hua; Jiang, Yinghui; Wang, Min; Wang, Peng; Shi, Guangxun; Ding, Mingjun

    2017-01-01

    Surface water samples were collected from 20 sampling sites throughout the Ganjiang River during pre-monsoon, monsoon, and post-monsoon seasons, and the concentrations of dissolved trace elements were determined by inductively coupled plasma-mass spectrometry (ICP-MS) for the spatial and seasonal variations, risk assessment, source identification, and categorization for risk area. The result demonstrated that concentrations of the elements exhibited significant seasonality. The high total element concentrations were detected at sites close to the intensive mining and urban activities. The concentrations of the elements were under the permissible limits as prescribed by related standards with a few exceptions. The most of heavy metal pollution index (HPI) values were lower than the critical index limit, indicating the basically clean water used as habitat for aquatic life. As was identified as the priority pollutant of non-carcinogenic and carcinogenic concerns, and the inhabitants ingesting the surface water at particular site might be subjected to the integrated health risks for exposure to the mixed trace elements. Multivariate statistical analyses confirmed that Zn, As, Cd, and Tl were derived from mining and urban activities; V, Cd, and Pb exhibited mixed origin; and Co, Ni, and Cu mainly resulted from natural processes. Three categorized risk areas corresponded to high, moderate, and low risks, respectively. As a whole, the upstream of the Ganjiang River was identified as the high-risk area relatively.

  10. Microscale characterization of the viscoelastic properties of hydrogel biomaterials using dual-mode ultrasound elastography.

    PubMed

    Hong, Xiaowei; Stegemann, Jan P; Deng, Cheri X

    2016-05-01

    Characterization of the microscale mechanical properties of biomaterials is a key challenge in the field of mechanobiology. Dual-mode ultrasound elastography (DUE) uses high frequency focused ultrasound to induce compression in a sample, combined with interleaved ultrasound imaging to measure the resulting deformation. This technique can be used to non-invasively perform creep testing on hydrogel biomaterials to characterize their viscoelastic properties. DUE was applied to a range of hydrogel constructs consisting of either hydroxyapatite (HA)-doped agarose, HA-collagen, HA-fibrin, or preosteoblast-seeded collagen constructs. DUE provided spatial and temporal mapping of local and bulk displacements and strains at high resolution. Hydrogel materials exhibited characteristic creep behavior, and the maximum strain and residual strain were both material- and concentration-dependent. Burger's viscoelastic model was used to extract characteristic parameters describing material behavior. Increased protein concentration resulted in greater stiffness and viscosity, but did not affect the viscoelastic time constant of acellular constructs. Collagen constructs exhibited significantly higher modulus and viscosity than fibrin constructs. Cell-seeded collagen constructs became stiffer with altered mechanical behavior as they developed over time. Importantly, DUE also provides insight into the spatial variation of viscoelastic properties at sub-millimeter resolution, allowing interrogation of the interior of constructs. DUE presents a novel technique for non-invasively characterizing hydrogel materials at the microscale, and therefore may have unique utility in the study of mechanobiology and the characterization of hydrogel biomaterials. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Differential parietal and temporal contributions to music perception in improvising and score-dependent musicians, an fMRI study.

    PubMed

    Harris, Robert; de Jong, Bauke M

    2015-10-22

    Using fMRI, cerebral activations were studied in 24 classically-trained keyboard performers and 12 musically unskilled control subjects. Two groups of musicians were recruited: improvising (n=12) and score-dependent (non-improvising) musicians (n=12). While listening to both familiar and unfamiliar music, subjects either (covertly) appraised the presented music performance or imagined they were playing the music themselves. We hypothesized that improvising musicians would exhibit enhanced efficiency of audiomotor transformation reflected by stronger ventral premotor activation. Statistical Parametric Mapping revealed that, while virtually 'playing along׳ with the music, improvising musicians exhibited activation of a right-hemisphere distribution of cerebral areas including posterior-superior parietal and dorsal premotor cortex. Involvement of these right-hemisphere dorsal stream areas suggests that improvising musicians recruited an amodal spatial processing system subserving pitch-to-space transformations to facilitate their virtual motor performance. Score-dependent musicians recruited a primarily left-hemisphere pattern of motor areas together with the posterior part of the right superior temporal sulcus, suggesting a relationship between aural discrimination and symbolic representation. Activations in bilateral auditory cortex were significantly larger for improvising musicians than for score-dependent musicians, suggesting enhanced top-down effects on aural perception. Our results suggest that learning to play a music instrument primarily from notation predisposes musicians toward aural identification and discrimination, while learning by improvisation involves audio-spatial-motor transformations, not only during performance, but also perception. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Examination of spotted sand bass (Paralabrax maculatofasciatus) pollutant bioaccumulation in San Diego Bay, San Diego, California

    PubMed Central

    2013-01-01

    The spotted sand bass (Paralabrax maculatofasciatus) is an important recreational sport and subsistence food fish within San Diego Bay, a large industrialized harbor in San Diego, California. Despite this importance, few studies examining the species life history relative to pollutant tissue concentrations and the consumptive fishery exist. This study utilized data from three independent spotted sand bass studies from 1989 to 2002 to investigate PCB, DDT, and mercury tissue concentrations relative to spotted sand bass age and growth in San Diego Bay, with subsequent comparisons to published pollutant advisory levels and fishery regulations for recreational and subsistence consumption of the species. Subsequent analysis focused on examining temporal and spatial differences for different regions of San Diego Bay. Study results for growth confirmed previous work, finding the species to exhibit highly asymptotic growth, making tissue pollutant concentrations at initial take size difficult if not impossible to predict. This was corroborated by independent tissue concentration results for mercury, which found no relationship between fish size and pollutant bioaccumulation observed. However, a positive though highly variable relationship was observed between fish size and PCB tissue concentration. Despite these findings, a significant proportion of fish exhibited pollutant levels above recommended state recreational angler consumption advisory levels for PCBs and mercury, especially for fish above the minimum take size, making the necessity of at-size predictions less critical. Lastly, no difference in tissue concentration was found temporally or spatially within San Diego Bay. PMID:24282672

  13. Examination of spotted sand bass (Paralabrax maculatofasciatus) pollutant bioaccumulation in San Diego Bay, San Diego, California.

    PubMed

    Loflen, Chad L

    2013-01-01

    The spotted sand bass (Paralabrax maculatofasciatus) is an important recreational sport and subsistence food fish within San Diego Bay, a large industrialized harbor in San Diego, California. Despite this importance, few studies examining the species life history relative to pollutant tissue concentrations and the consumptive fishery exist. This study utilized data from three independent spotted sand bass studies from 1989 to 2002 to investigate PCB, DDT, and mercury tissue concentrations relative to spotted sand bass age and growth in San Diego Bay, with subsequent comparisons to published pollutant advisory levels and fishery regulations for recreational and subsistence consumption of the species. Subsequent analysis focused on examining temporal and spatial differences for different regions of San Diego Bay. Study results for growth confirmed previous work, finding the species to exhibit highly asymptotic growth, making tissue pollutant concentrations at initial take size difficult if not impossible to predict. This was corroborated by independent tissue concentration results for mercury, which found no relationship between fish size and pollutant bioaccumulation observed. However, a positive though highly variable relationship was observed between fish size and PCB tissue concentration. Despite these findings, a significant proportion of fish exhibited pollutant levels above recommended state recreational angler consumption advisory levels for PCBs and mercury, especially for fish above the minimum take size, making the necessity of at-size predictions less critical. Lastly, no difference in tissue concentration was found temporally or spatially within San Diego Bay.

  14. Predicting extinction debt from community patterns.

    PubMed

    Kitzes, Justin; Harte, John

    2015-08-01

    A significant challenge in both measuring and predicting species extinction rates at global and local scales is the possibility of extinction debt, time-delayed extinctions that occur gradually following an initial impact. Here we examine how relative abundance distributions and spatial aggregation combine to influence the likely magnitude of future extinction debt following habitat loss or climate-driven range contraction. Our analysis is based on several fundamental premises regarding abundance distributions, most importantly that species abundances immediately following habitat loss are a sample from an initial relative abundance distribution and that the long-term, steady-state form of the species abundance distribution is a property of the biology of a community and not of area. Under these two hypotheses, the results show that communities following canonical lognormal and broken-stick abundance distributions are prone to exhibit extinction debt, especially when species exhibit low spatial aggregation. Conversely, communities following a logseries distribution with a constant Fisher's α parameter never demonstrate extinction debt and often show an "immigration credit," in which species richness rises in the long term following an initial decrease. An illustration of these findings in 25 biodiversity hotspots suggests a negligible immediate extinction rate for bird communities and eventual extinction debts of 30-50% of initial species richness, whereas plant communities are predicted to immediately lose 5-15% of species without subsequent extinction debt. These results shed light on the basic determinants of extinction debt and provide initial indications of the magnitude of likely debts in landscapes where few empirical data are available.

  15. Toward a Definition of Intrinsic Axes: The Effect of Orthogonality and Symmetry on the Preferred Direction of Spatial Memory

    ERIC Educational Resources Information Center

    Richard, Laurence; Waller, David

    2013-01-01

    Mou, Zhao, and McNamara (2007) proposed the "intrinsic model of human spatial memory," which posits that a viewer's memory of an array of objects will exhibit a preferred direction that is aligned with an intrinsic axis of the array. They defined intrinsic axes as salient axes created in part by the physical (geometric) properties of the…

  16. Gravity orientation tuning in macaque anterior thalamus.

    PubMed

    Laurens, Jean; Kim, Byounghoon; Dickman, J David; Angelaki, Dora E

    2016-12-01

    Gravity may provide a ubiquitous allocentric reference to the brain's spatial orientation circuits. Here we describe neurons in the macaque anterior thalamus tuned to pitch and roll orientation relative to gravity, independently of visual landmarks. We show that individual cells exhibit two-dimensional tuning curves, with peak firing rates at a preferred vertical orientation. These results identify a thalamic pathway for gravity cues to influence perception, action and spatial cognition.

  17. Disruption of spatial organization and interjoint coordination in Parkinson's disease, progressive supranuclear palsy, and multiple system atrophy.

    PubMed

    Leiguarda, R; Merello, M; Balej, J; Starkstein, S; Nogues, M; Marsden, C D

    2000-07-01

    Patients with basal ganglia diseases may exhibit ideomotor apraxia. To define the nature of the impairment of the action production system, we studied a repetitive gesture of slicing bread by three-dimensional computergraphic analysis in eight nondemented patients with Parkinson's disease in the "on" state, five with progressive supranuclear palsy and four with multiple system atrophy. Two patients with Parkinson's disease and two with progressive supranuclear palsy showed ideomotor apraxia for transitive movements on standard testing. A Selspott II system was used for kinematic analysis of wrist trajectories and angular motions of the shoulder and elbow joints. Patients with Parkinson's disease, progressive supranuclear palsy, and even some with multiple system atrophy exhibited kinematic deficits in the spatial precision of movement and velocity-curvature relationships; in addition, they failed to maintain proper angle/angle relationships and to apportion their relative joint amplitudes normally. Spatial disruption of wrist trajectories was more severe in patients with ideomotor apraxia. We posit that the basal ganglia are part of the parallel parieto-frontal circuits devoted to sensorimotor integration for object-oriented behavior. The severity and characteristics of spatial abnormalities of a transitive movement would therefore depend on the location and distribution of the pathologic process within these circuits.

  18. Spatial structuring within a reservoir fish population: implications for management

    USGS Publications Warehouse

    Stewart, David R.; Long, James M.; Shoup, Daniel E.

    2014-01-01

    Spatial structuring in reservoir fish populations can exist because of environmental gradients, species-specific behaviour, or even localised fishing effort. The present study investigated whether white crappie exhibited evidence of improved population structure where the northern more productive half of a lake is closed to fishing to provide waterfowl hunting opportunities. Population response to angling was modelled for each substock of white crappie (north (protected) and south (unprotected) areas), the entire lake (single-stock model) and by combining simulations of the two independent substock models (additive model). White crappie in the protected area were more abundant, consisting of larger, older individuals, and exhibited a lower total annual mortality rate than in the unprotected area. Population modelling found that fishing mortality rates between 0.1 and 0.3 resulted in sustainable populations (spawning potential ratios (SPR) >0.30). The population in the unprotected area appeared to be more resilient (SPR > 0.30) at the higher fishing intensities (0.35–0.55). Considered additively, the whole-lake fishery appeared more resilient than when modelled as a single-panmictic stock. These results provided evidence of spatial structuring in reservoir fish populations, and we recommend model assessments used to guide management decisions should consider those spatial differences in other populations where they exist.

  19. Endometrial apoptosis and neutrophil infiltration during menstruation exhibits spatial and temporal dynamics that are recapitulated in a mouse model.

    PubMed

    Armstrong, Gregory M; Maybin, Jacqueline A; Murray, Alison A; Nicol, Moira; Walker, Catherine; Saunders, Philippa T K; Rossi, Adriano G; Critchley, Hilary O D

    2017-12-12

    Menstruation is characterised by synchronous shedding and restoration of tissue integrity. An in vivo model of menstruation is required to investigate mechanisms responsible for regulation of menstrual physiology and to investigate common pathologies such as heavy menstrual bleeding (HMB). We hypothesised that our mouse model of simulated menstruation would recapitulate the spatial and temporal changes in the inflammatory microenvironment of human menses. Three regulatory events were investigated: cell death (apoptosis), neutrophil influx and cytokine/chemokine expression. Well-characterised endometrial tissues from women were compared with uteri from a mouse model (tissue recovered 0, 4, 8, 24 and 48 h after removal of a progesterone-secreting pellet). Immunohistochemistry for cleaved caspase-3 (CC3) revealed significantly increased staining in human endometrium from late secretory and menstrual phases. In mice, CC3 was significantly increased at 8 and 24 h post-progesterone-withdrawal. Elastase + human neutrophils were maximal during menstruation; Ly6G + mouse neutrophils were maximal at 24 h. Human endometrial and mouse uterine cytokine/chemokine mRNA concentrations were significantly increased during menstrual phase and 24 h post-progesterone-withdrawal respectively. Data from dated human samples revealed time-dependent changes in endometrial apoptosis preceding neutrophil influx and cytokine/chemokine induction during active menstruation. These dynamic changes were recapitulated in the mouse model of menstruation, validating its use in menstrual research.

  20. Living on the Edges: Spatial Niche Occupation of Asian Citrus Psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae), in Citrus Groves.

    PubMed

    Sétamou, Mamoudou; Bartels, David W

    2015-01-01

    The spatial niche occupation of the Asian citrus psyllid, Diaphorina citri Kuwayama, 1908, was evaluated to determine its field colonization and food resource exploitation strategies in citrus groves. Mature grapefruit and sweet orange groves were surveyed as part of an area-wide program in 2009-2010 to determine D. citri population densities and between-tree distribution. In both cultivars, significantly more psyllids were found on perimeter trees throughout the study period suggesting a strong edge effect in D. citri distribution in the groves. D. citri densities and infestation levels gradually declined from the edge to the center of grove. Higher numbers of D. citri were recorded on trees located on the east and south sides of the groves than those on the west and north sides. Citrus groves located at the outer edge of the study with at least one side non-surrounded to other citrus groves harbored significantly more D. citri than groves located within the block cluster and entirely surrounded by other groves. In detailed field studies during 2012, infestation of D. citri started from border trees in the grove where possibly one generation is completed before inner trees become infested. In addition, psyllid densities decreased significantly with increasing distance from the grove edge. Using the selection index, D citri exhibited a strong niche occupation preference for border trees.

  1. Living on the Edges: Spatial Niche Occupation of Asian Citrus Psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae), in Citrus Groves

    PubMed Central

    2015-01-01

    The spatial niche occupation of the Asian citrus psyllid, Diaphorina citri Kuwayama, 1908, was evaluated to determine its field colonization and food resource exploitation strategies in citrus groves. Mature grapefruit and sweet orange groves were surveyed as part of an area-wide program in 2009–2010 to determine D. citri population densities and between-tree distribution. In both cultivars, significantly more psyllids were found on perimeter trees throughout the study period suggesting a strong edge effect in D. citri distribution in the groves. D. citri densities and infestation levels gradually declined from the edge to the center of grove. Higher numbers of D. citri were recorded on trees located on the east and south sides of the groves than those on the west and north sides. Citrus groves located at the outer edge of the study with at least one side non-surrounded to other citrus groves harbored significantly more D. citri than groves located within the block cluster and entirely surrounded by other groves. In detailed field studies during 2012, infestation of D. citri started from border trees in the grove where possibly one generation is completed before inner trees become infested. In addition, psyllid densities decreased significantly with increasing distance from the grove edge. Using the selection index, D citri exhibited a strong niche occupation preference for border trees. PMID:26193111

  2. Chronic groundwater decline: A multi-decadal analysis of groundwater trends under extreme climate cycles

    NASA Astrophysics Data System (ADS)

    Le Brocque, Andrew F.; Kath, Jarrod; Reardon-Smith, Kathryn

    2018-06-01

    Chronic groundwater decline is a concern in many of the world's major agricultural areas. However, a general lack of accurate long-term in situ measurement of groundwater depth and analysis of trends prevents understanding of the dynamics of these systems at landscape scales. This is particularly worrying in the context of future climate uncertainties. This study examines long-term groundwater responses to climate variability in a major agricultural production landscape in southern Queensland, Australia. Based on records for 381 groundwater bores, we used a modified Mann-Kendall non-parametric test and Sen's slope estimator to determine groundwater trends across a 26-year period (1989-2015) and in distinct wet and dry climatic phases. Comparison of trends between climatic phases showed groundwater level recovery during wet phases was insufficient to offset the decline in groundwater level from the previous dry phase. Across the entire 26-year sampling period, groundwater bore levels (all bores) showed an overall significant declining trend (p < 0.05) of an average 0.06 m year-1. Fifty-one bores (20%) exhibited significant declining groundwater levels (p < 0.05), 25 bores (10%) exhibited significant rising groundwater levels (p < 0.05), and 175 bores (70%) exhibited no significant change in groundwater levels (p > 0.05). Spatially, both declining and rising bores were highly clustered. We conclude that over 1989-2015 there is a significant net decline in groundwater levels driven by a smaller subset of highly responsive bores in high irrigation areas within the catchment. Despite a number of targeted policy interventions, chronic groundwater decline remains evident in the catchment. We argue that this is likely to continue and to occur more widely under potential climate change and that policy makers, groundwater users and managers need to engage in planning to ensure the sustainability of this vital resource.

  3. Change of spatial information under rescaling: A case study using multi-resolution image series

    NASA Astrophysics Data System (ADS)

    Chen, Weirong; Henebry, Geoffrey M.

    Spatial structure in imagery depends on a complicated interaction between the observational regime and the types and arrangements of entities within the scene that the image portrays. Although block averaging of pixels has commonly been used to simulate coarser resolution imagery, relatively little attention has been focused on the effects of simple rescaling on spatial structure and the explanation and a possible solution to the problem. Yet, if there are significant differences in spatial variance between rescaled and observed images, it may affect the reliability of retrieved biogeophysical quantities. To investigate these issues, a nested series of high spatial resolution digital imagery was collected at a research site in eastern Nebraska in 2001. An airborne Kodak DCS420IR camera acquired imagery at three altitudes, yielding nominal spatial resolutions ranging from 0.187 m to 1 m. The red and near infrared (NIR) bands of the co-registered image series were normalized using pseudo-invariant features, and the normalized difference vegetation index (NDVI) was calculated. Plots of grain sorghum planted in orthogonal crop row orientations were extracted from the image series. The finest spatial resolution data were then rescaled by averaging blocks of pixels to produce a rescaled image series that closely matched the spatial resolution of the observed image series. Spatial structures of the observed and rescaled image series were characterized using semivariogram analysis. Results for NDVI and its component bands show, as expected, that decreasing spatial resolution leads to decreasing spatial variability and increasing spatial dependence. However, compared to the observed data, the rescaled images contain more persistent spatial structure that exhibits limited variation in both spatial dependence and spatial heterogeneity. Rescaling via simple block averaging fails to consider the effect of scene object shape and extent on spatial information. As the features portrayed by pixels are equally weighted regardless of the shape and extent of the underlying scene objects, the rescaled image retains more of the original spatial information than would occur through direct observation at a coarser sensor spatial resolution. In contrast, for the observed images, due to the effect of the modulation transfer function (MTF) of the imaging system, high frequency features like edges are blurred or lost as the pixel size increases, resulting in greater variation in spatial structure. Successive applications of a low-pass spatial convolution filter are shown to mimic a MTF. Accordingly, it is recommended that such a procedure be applied prior to rescaling by simple block averaging, if insufficient image metadata exist to replicate the net MTF of the imaging system, as might be expected in land cover change analysis studies using historical imagery.

  4. Spatiotemporal changes of normalized difference vegetation index (NDVI) and response to climate extremes and ecological restoration in the Loess Plateau, China

    NASA Astrophysics Data System (ADS)

    Zhao, Anzhou; Zhang, Anbing; Liu, Xianfeng; Cao, Sen

    2018-04-01

    Extreme drought, precipitation, and other extreme climatic events often have impacts on vegetation. Based on meteorological data from 52 stations in the Loess Plateau (LP) and a satellite-derived normalized difference vegetation index (NDVI) from the third-generation Global Inventory Modeling and Mapping Studies (GIMMS3g) dataset, this study investigated the relationship between vegetation change and climatic extremes from 1982 to 2013. Our results showed that the vegetation coverage increased significantly, with a linear rate of 0.025/10a ( P < 0.001) from 1982 to 2013. As for the spatial distribution, NDVI revealed an increasing trend from the northwest to the southeast, with about 61.79% of the LP exhibiting a significant increasing trend ( P < 0.05). Some temperature extreme indices, including TMAXmean, TMINmean, TN90p, TNx, TX90p, and TXx, increased significantly at rates of 0.77 mm/10a, 0.52 °C/10a, 0.62 °C/10a, 0.80 °C/10a, 5.16 days/10a, and 0.65 °C/10a, respectively. On the other hand, other extreme temperature indices including TX10p and TN10p decreased significantly at rates of -2.77 days/10a and 4.57 days/10a ( P < 0.01), respectively. Correlation analysis showed that only TMINmean had a significant relationship with NDVI at the yearly time scale ( P < 0.05). At the monthly time scale, vegetation coverage and different vegetation types responded significantly positively to precipitation and temperature extremes (TMAXmean, TMINmean, TNx, TNn, TXn, and TXx) ( P < 0.01). All of the precipitation extremes and temperature extremes exhibited significant positive relationships with NDVI during the spring and autumn ( P < 0.01). However, the relationship between NDVI and RX1day, TMAXmean, TXn, and TXx was insignificant in summer. Vegetation exhibited a significant negative relationship with precipitation extremes in winter ( P < 0.05). In terms of human activity, our results indicate a strong correlation between the cumulative afforestation area and NDVI in Yan'an and Yulin during 1998-2013, r = 0.859 and 0.85, n = 16, P < 0.001.

  5. Cerebellar contribution to spatial event processing: involvement in procedural and working memory components.

    PubMed

    Mandolesi, L; Leggio, M G; Graziano, A; Neri, P; Petrosini, L

    2001-12-01

    Spatial function is one of the cognitive functions altered in the presence of cerebellar lesions. We investigated the cerebellar contribution to the acquisition of spatial procedural and working memory components by means of a radial maze. To establish whether a cerebellar lesion would cause a deficit in solving the radial maze, a first experiment was carried out by using a full-baited maze procedure in different experimental groups, with or without cerebellar lesion and with or without pretraining. Non-pretrained hemicerebellectomized (HCbed) animals exhibited impaired performances in all (motor, spatial and procedural) task aspects. Pre-trained HCbed animals performed similarly to control animals in the task aspects linked to the processing of spatial and procedural factors. To distinguish procedural from working memory components, a forced-choice paradigm of the radial maze was used in the second experiment. Non-pretrained HCbed rats continued to make a lot of errors and show severe perseverative tendencies, already observed in the first experiment, supporting a specific cerebellar role in acquiring new behaviours and in modifying them in relation to the context. Interestingly, hindered from putting the acquired explorative patterns into action and compelled to use only working memory abilities, the pretrained HCbed group exhibited a dramatic worsening of performance. In conclusion, the present findings demonstrate that cerebellar damage induces a specific behaviour in radial maze tasks, characterized by an inflexible use of the procedures (if indeed any procedure was acquired before the lesion) and by a severe impairment in working memory processes.

  6. Role of spatial inhomogenity in GPCR dimerisation predicted by receptor association-diffusion models

    NASA Astrophysics Data System (ADS)

    Deshpande, Sneha A.; Pawar, Aiswarya B.; Dighe, Anish; Athale, Chaitanya A.; Sengupta, Durba

    2017-06-01

    G protein-coupled receptor (GPCR) association is an emerging paradigm with far reaching implications in the regulation of signalling pathways and therapeutic interventions. Recent super resolution microscopy studies have revealed that receptor dimer steady state exhibits sub-second dynamics. In particular the GPCRs, muscarinic acetylcholine receptor M1 (M1MR) and formyl peptide receptor (FPR), have been demonstrated to exhibit a fast association/dissociation kinetics, independent of ligand binding. In this work, we have developed a spatial kinetic Monte Carlo model to investigate receptor homo-dimerisation at a single receptor resolution. Experimentally measured association/dissociation kinetic parameters and diffusion coefficients were used as inputs to the model. To test the effect of membrane spatial heterogeneity on the simulated steady state, simulations were compared to experimental statistics of dimerisation. In the simplest case the receptors are assumed to be diffusing in a spatially homogeneous environment, while spatial heterogeneity is modelled to result from crowding, membrane micro-domains and cytoskeletal compartmentalisation or ‘corrals’. We show that a simple association-diffusion model is sufficient to reproduce M1MR association statistics, but fails to reproduce FPR statistics despite comparable kinetic constants. A parameter sensitivity analysis is required to reproduce the association statistics of FPR. The model reveals the complex interplay between cytoskeletal components and their influence on receptor association kinetics within the features of the membrane landscape. These results constitute an important step towards understanding the factors modulating GPCR organisation.

  7. An implicit spatial and high-order temporal finite difference scheme for 2D acoustic modelling

    NASA Astrophysics Data System (ADS)

    Wang, Enjiang; Liu, Yang

    2018-01-01

    The finite difference (FD) method exhibits great superiority over other numerical methods due to its easy implementation and small computational requirement. We propose an effective FD method, characterised by implicit spatial and high-order temporal schemes, to reduce both the temporal and spatial dispersions simultaneously. For the temporal derivative, apart from the conventional second-order FD approximation, a special rhombus FD scheme is included to reach high-order accuracy in time. Compared with the Lax-Wendroff FD scheme, this scheme can achieve nearly the same temporal accuracy but requires less floating-point operation times and thus less computational cost when the same operator length is adopted. For the spatial derivatives, we adopt the implicit FD scheme to improve the spatial accuracy. Apart from the existing Taylor series expansion-based FD coefficients, we derive the least square optimisation based implicit spatial FD coefficients. Dispersion analysis and modelling examples demonstrate that, our proposed method can effectively decrease both the temporal and spatial dispersions, thus can provide more accurate wavefields.

  8. How noise and coupling influence leading indicators of population extinction in a spatially extended ecological system.

    PubMed

    O'Regan, Suzanne M

    2018-12-01

    Anticipating critical transitions in spatially extended systems is a key topic of interest to ecologists. Gradually declining metapopulations are an important example of a spatially extended biological system that may exhibit a critical transition. Theory for spatially extended systems approaching extinction that accounts for environmental stochasticity and coupling is currently lacking. Here, we develop spatially implicit two-patch models with additive and multiplicative forms of environmental stochasticity that are slowly forced through population collapse, through changing environmental conditions. We derive patch-specific expressions for candidate indicators of extinction and test their performance via a simulation study. Coupling and spatial heterogeneities decrease the magnitude of the proposed indicators in coupled populations relative to isolated populations, and the noise regime and the degree of coupling together determine trends in summary statistics. This theory may be readily applied to other spatially extended ecological systems, such as coupled infectious disease systems on the verge of elimination.

  9. The Association between Environmental Factors and Scarlet Fever Incidence in Beijing Region: Using GIS and Spatial Regression Models

    PubMed Central

    Mahara, Gehendra; Wang, Chao; Yang, Kun; Chen, Sipeng; Guo, Jin; Gao, Qi; Wang, Wei; Wang, Quanyi; Guo, Xiuhua

    2016-01-01

    (1) Background: Evidence regarding scarlet fever and its relationship with meteorological, including air pollution factors, is not very available. This study aimed to examine the relationship between ambient air pollutants and meteorological factors with scarlet fever occurrence in Beijing, China. (2) Methods: A retrospective ecological study was carried out to distinguish the epidemic characteristics of scarlet fever incidence in Beijing districts from 2013 to 2014. Daily incidence and corresponding air pollutant and meteorological data were used to develop the model. Global Moran’s I statistic and Anselin’s local Moran’s I (LISA) were applied to detect the spatial autocorrelation (spatial dependency) and clusters of scarlet fever incidence. The spatial lag model (SLM) and spatial error model (SEM) including ordinary least squares (OLS) models were then applied to probe the association between scarlet fever incidence and meteorological including air pollution factors. (3) Results: Among the 5491 cases, more than half (62%) were male, and more than one-third (37.8%) were female, with the annual average incidence rate 14.64 per 100,000 population. Spatial autocorrelation analysis exhibited the existence of spatial dependence; therefore, we applied spatial regression models. After comparing the values of R-square, log-likelihood and the Akaike information criterion (AIC) among the three models, the OLS model (R2 = 0.0741, log likelihood = −1819.69, AIC = 3665.38), SLM (R2 = 0.0786, log likelihood = −1819.04, AIC = 3665.08) and SEM (R2 = 0.0743, log likelihood = −1819.67, AIC = 3665.36), identified that the spatial lag model (SLM) was best for model fit for the regression model. There was a positive significant association between nitrogen oxide (p = 0.027), rainfall (p = 0.036) and sunshine hour (p = 0.048), while the relative humidity (p = 0.034) had an adverse association with scarlet fever incidence in SLM. (4) Conclusions: Our findings indicated that meteorological, as well as air pollutant factors may increase the incidence of scarlet fever; these findings may help to guide scarlet fever control programs and targeting the intervention. PMID:27827946

  10. The Association between Environmental Factors and Scarlet Fever Incidence in Beijing Region: Using GIS and Spatial Regression Models.

    PubMed

    Mahara, Gehendra; Wang, Chao; Yang, Kun; Chen, Sipeng; Guo, Jin; Gao, Qi; Wang, Wei; Wang, Quanyi; Guo, Xiuhua

    2016-11-04

    (1) Background: Evidence regarding scarlet fever and its relationship with meteorological, including air pollution factors, is not very available. This study aimed to examine the relationship between ambient air pollutants and meteorological factors with scarlet fever occurrence in Beijing, China. (2) Methods: A retrospective ecological study was carried out to distinguish the epidemic characteristics of scarlet fever incidence in Beijing districts from 2013 to 2014. Daily incidence and corresponding air pollutant and meteorological data were used to develop the model. Global Moran's I statistic and Anselin's local Moran's I (LISA) were applied to detect the spatial autocorrelation (spatial dependency) and clusters of scarlet fever incidence. The spatial lag model (SLM) and spatial error model (SEM) including ordinary least squares (OLS) models were then applied to probe the association between scarlet fever incidence and meteorological including air pollution factors. (3) Results: Among the 5491 cases, more than half (62%) were male, and more than one-third (37.8%) were female, with the annual average incidence rate 14.64 per 100,000 population. Spatial autocorrelation analysis exhibited the existence of spatial dependence; therefore, we applied spatial regression models. After comparing the values of R-square, log-likelihood and the Akaike information criterion (AIC) among the three models, the OLS model (R² = 0.0741, log likelihood = -1819.69, AIC = 3665.38), SLM (R² = 0.0786, log likelihood = -1819.04, AIC = 3665.08) and SEM (R² = 0.0743, log likelihood = -1819.67, AIC = 3665.36), identified that the spatial lag model (SLM) was best for model fit for the regression model. There was a positive significant association between nitrogen oxide ( p = 0.027), rainfall ( p = 0.036) and sunshine hour ( p = 0.048), while the relative humidity ( p = 0.034) had an adverse association with scarlet fever incidence in SLM. (4) Conclusions: Our findings indicated that meteorological, as well as air pollutant factors may increase the incidence of scarlet fever; these findings may help to guide scarlet fever control programs and targeting the intervention.

  11. The Composition and Spatial Patterns of Bacterial Virulence Factors and Antibiotic Resistance Genes in 19 Wastewater Treatment Plants

    PubMed Central

    Zhang, Bing; Xia, Yu; Wen, Xianghua; Wang, Xiaohui; Yang, Yunfeng; Zhou, Jizhong; Zhang, Yu

    2016-01-01

    Bacterial pathogenicity and antibiotic resistance are of concern for environmental safety and public health. Accumulating evidence suggests that wastewater treatment plants (WWTPs) are as an important sink and source of pathogens and antibiotic resistance genes (ARGs). Virulence genes (encoding virulence factors) are good indicators for bacterial pathogenic potentials. To achieve a comprehensive understanding of bacterial pathogenic potentials and antibiotic resistance in WWTPs, bacterial virulence genes and ARGs in 19 WWTPs covering a majority of latitudinal zones of China were surveyed by using GeoChip 4.2. A total of 1610 genes covering 13 virulence factors and 1903 genes belonging to 11 ARG families were detected respectively. The bacterial virulence genes exhibited significant spatial distribution patterns of a latitudinal biodiversity gradient and a distance-decay relationship across China. Moreover, virulence genes tended to coexist with ARGs as shown by their strongly positive associations. In addition, key environmental factors shaping the overall virulence gene structure were identified. This study profiles the occurrence, composition and distribution of virulence genes and ARGs in current WWTPs in China, and uncovers spatial patterns and important environmental variables shaping their structure, which may provide the basis for further studies of bacterial virulence factors and antibiotic resistance in WWTPs. PMID:27907117

  12. Spatial diversity of bacterioplankton communities in surface water of northern South China Sea.

    PubMed

    Li, Jialin; Li, Nan; Li, Fuchao; Zou, Tao; Yu, Shuxian; Wang, Yinchu; Qin, Song; Wang, Guangyi

    2014-01-01

    The South China Sea is one of the largest marginal seas, with relatively frequent passage of eddies and featuring distinct spatial variation in the western tropical Pacific Ocean. Here, we report a phylogenetic study of bacterial community structures in surface seawater of the northern South China Sea (nSCS). Samples collected from 31 sites across large environmental gradients were used to construct clone libraries and yielded 2,443 sequences grouped into 170 OTUs. Phylogenetic analysis revealed 23 bacterial classes with major components α-, β- and γ-Proteobacteria, as well as Cyanobacteria. At class and genus taxon levels, community structure of coastal waters was distinctively different from that of deep-sea waters and displayed a higher diversity index. Redundancy analyses revealed that bacterial community structures displayed a significant correlation with the water depth of individual sampling sites. Members of α-Proteobacteria were the principal component contributing to the differences of the clone libraries. Furthermore, the bacterial communities exhibited heterogeneity within zones of upwelling and anticyclonic eddies. Our results suggested that surface bacterial communities in nSCS had two-level patterns of spatial distribution structured by ecological types (coastal VS. oceanic zones) and mesoscale physical processes, and also provided evidence for bacterial phylogenetic phyla shaped by ecological preferences.

  13. Spatiotemporal Risk of Bacillary Dysentery and Sensitivity to Meteorological Factors in Hunan Province, China.

    PubMed

    Xu, Chengdong; Xiao, Gexin; Wang, Jinfeng; Zhang, Xiangxue; Liang, Jinjun

    2017-12-29

    Bacillary dysentery remains a public health concern in the world. Hunan Province is one of the provinces having the highest risk of bacillary dysentery in China, however, the spatial-temporal distribution, variation of bacillary dysentery and sensitivity to meteorological factors in there are unclear. In this paper, a Bayesian space-time hierarchical model (BSTHM) was used to detect space-time variation, and effects of meteorological factors between 2010 and 2015. The risk of bacillary dysentery showed apparent spatial-temporal heterogeneity. The highest risk occurred in the summer season. Economically undeveloped mountainous areas in the west and south of the province had the highest incidence rates. Twenty three (18.9%) and 20 (16.4%) counties were identified as hot and cold spots, respectively. Among the hotspots, 11 counties (47.8%) exhibited a rapidly decreasing trend, suggesting they may become low-risk areas in the future. Of the cold spot counties, six (30%) showed a slowly decreasing trend, and may have a higher risk in the future. Among meteorological factors, air temperature, relative humidity, and wind speed all played a significant role in the spatial-temporal distribution of bacillary dysentery risk. These findings can contribute to the implementation of an early warning system for controlling and preventing bacillary dysentery.

  14. Spatiotemporal Risk of Bacillary Dysentery and Sensitivity to Meteorological Factors in Hunan Province, China

    PubMed Central

    Xu, Chengdong; Xiao, Gexin; Wang, Jinfeng; Zhang, Xiangxue; Liang, Jinjun

    2017-01-01

    Bacillary dysentery remains a public health concern in the world. Hunan Province is one of the provinces having the highest risk of bacillary dysentery in China, however, the spatial-temporal distribution, variation of bacillary dysentery and sensitivity to meteorological factors in there are unclear. In this paper, a Bayesian space-time hierarchical model (BSTHM) was used to detect space-time variation, and effects of meteorological factors between 2010 and 2015. The risk of bacillary dysentery showed apparent spatial-temporal heterogeneity. The highest risk occurred in the summer season. Economically undeveloped mountainous areas in the west and south of the province had the highest incidence rates. Twenty three (18.9%) and 20 (16.4%) counties were identified as hot and cold spots, respectively. Among the hotspots, 11 counties (47.8%) exhibited a rapidly decreasing trend, suggesting they may become low-risk areas in the future. Of the cold spot counties, six (30%) showed a slowly decreasing trend, and may have a higher risk in the future. Among meteorological factors, air temperature, relative humidity, and wind speed all played a significant role in the spatial-temporal distribution of bacillary dysentery risk. These findings can contribute to the implementation of an early warning system for controlling and preventing bacillary dysentery. PMID:29286297

  15. Long-term effects of cannabis on oculomotor function in humans.

    PubMed

    Huestegge, L; Radach, R; Kunert, H J

    2009-08-01

    Cannabis is known to affect human cognitive and visuomotor skills directly after consumption. Some studies even point to rather long-lasting effects, especially after chronic tetrahydrocannabinol (THC) abuse. However, it is still unknown whether long-term effects on basic visual and oculomotor processing may exist. In the present study, the performance of 20 healthy long-term cannabis users without acute THC intoxication and 20 control subjects were examined in four basic visuomotor paradigms to search for specific long-term impairments. Subjects were asked to perform: 1) reflexive saccades to visual targets (prosaccades), including gap and overlap conditions, 2) voluntary antisaccades, 3) memory-guided saccades and 4) double-step saccades. Spatial and temporal parameters of the saccades were subsequently analysed. THC subjects exhibited a significant increase of latency in the prosaccade and antisaccade tasks, as well as prolonged saccade amplitudes in the antisaccade and memory-guided task, compared with the control subjects. The results point to substantial and specific long-term deficits in basic temporal processing of saccades and impaired visuo-spatial working memory. We suggest that these impairments are a major contributor to degraded performance of chronic users in a vital everyday task like visual search, and they might potentially also affect spatial navigation and reading.

  16. Deep data: discovery and visualization Application to hyperspectral ALMA imagery

    NASA Astrophysics Data System (ADS)

    Merényi, Erzsébet; Taylor, Joshua; Isella, Andrea

    2017-06-01

    Leading-edge telescopes such as the Atacama Large Millimeter and sub-millimeter Array (ALMA), and near-future ones, are capable of imaging the same sky area at hundreds-to-thousands of frequencies with both high spectral and spatial resolution. This provides unprecedented opportunities for discovery about the spatial, kinematical and compositional structure of sources such as molecular clouds or protoplanetary disks, and more. However, in addition to enormous volume, the data also exhibit unprecedented complexity, mandating new approaches for extracting and summarizing relevant information. Traditional techniques such as examining images at selected frequencies become intractable while tools that integrate data across frequencies or pixels (like moment maps) can no longer fully exploit and visualize the rich information. We present a neural map-based machine learning approach that can handle all spectral channels simultaneously, utilizing the full depth of these data for discovery and visualization of spectrally homogeneous spatial regions (spectral clusters) that characterize distinct kinematic behaviors. We demonstrate the effectiveness on an ALMA image cube of the protoplanetary disk HD142527. The tools we collectively name ``NeuroScope'' are efficient for ``Big Data'' due to intelligent data summarization that results in significant sparsity and noise reduction. We also demonstrate a new approach to automate our clustering for fast distillation of large data cubes.

  17. Spatial distributions of polyunsaturated aldehydes and their biogeochemical implications in the Pearl River Estuary and the adjacent northern South China Sea

    NASA Astrophysics Data System (ADS)

    Wu, Zhengchao; Li, Qian P.

    2016-09-01

    This study reports the first comprehensive exploration of the spatial patterns of dissolved and particulate polyunsaturated aldehydes (PUAs), their physical and biological controlling factors, and their potential biogeochemical influences in the Pearl River Estuary (PRE) of the northern South China Sea (NSCS). High levels of total particulate PUAs (0-41 nM) and dissolved PUAs (0.10-0.37 nM) were observed with substantial spatial variation during an intense summer phytoplankton bloom outside the PRE mouth. We found the particulate PUAs strongly correlated with temperature within the high chlorophyll bloom, while showing a generally positive correlation with chlorophyll-a for the entire region. Additionally, the Si/N ratio significantly correlated with the particulate PUAs along the estuary suggesting the important role of silica on PUA production in this region. The dissolved PUAs counterparts exhibited a positive correlation with chlorophyll-a within the high chlorophyll bloom, but a negatively one with temperature outside, reflecting the essential bio-physical coupling effects on the dissolved PUAs distributions in the ocean. Biogeochemical implications of PUAs on the coastal ecosystem include not only the deleterious restriction of high PUAs-producing diatom bloom on copepod population, but also the profound influence of particulate PUAs on the microbial cycling of organic carbon in the NSCS.

  18. Dispersal scaling from the world's rivers

    USGS Publications Warehouse

    Warrick, J.A.; Fong, D.A.

    2004-01-01

    Although rivers provide important biogeochemical inputs to oceans, there are currently no descriptive or predictive relationships of the spatial scales of these river influences. Our combined satellite, laboratory, field and modeling results show that the coastal dispersal areas of small, mountainous rivers exhibit remarkable self-similar scaling relationships over many orders of magnitude. River plume areas scale with source drainage area to a power significantly less than one (average = 0.65), and this power relationship decreases significantly with distance offshore of the river mouth. Observations of plumes from large rivers reveal that this scaling continues over six orders of magnitude of river drainage basin areas. This suggests that the cumulative area of coastal influence for many of the smallest rivers of the world is greater than that of single rivers of equal watershed size. Copyright 2004 by the American Geophysical Union.

  19. Geographic variation in patterns of nestedness among local stream fish assemblages in Virginia

    USGS Publications Warehouse

    Cook, R.R.; Angermeier, P.L.; Finn, D.S.; Poff, N.L.; Krueger, K.L.

    2004-01-01

    Nestedness of faunal assemblages is a multiscale phenomenon, potentially influenced by a variety of factors. Prior small-scale studies have found freshwater fish species assemblages to be nested along stream courses as a result of either selective colonization or extinction. However, within-stream gradients in temperature and other factors are correlated with the distributions of many fish species and may also contribute to nestedness. At a regional level, strongly nested patterns would require a consistent set of structuring mechanisms across streams, and correlation among species' tolerances of the environmental factors that influence distribution. Thus, nestedness should be negatively associated with the spatial extent of the region analyzed and positively associated with elevational gradients (a correlate of temperature and other environmental factors). We examined these relationships for the freshwater fishes of Virginia. Regions were defined within a spatial hierarchy and included whole river drainages, portions of drainages within physiographic provinces, and smaller subdrainages. In most cases, nestedness was significantly stronger in regions of smaller spatial extent and in regions characterized by greater topographic relief. Analysis of hydrologic variability and patterns of faunal turnover provided no evidence that interannual colonization/extinction dynamics contributed to elevational differences in nestedness. These results suggest that, at regional scales, nestedness is influenced by interactions between biotic and abiotic factors, and that the strongest nestedness is likely to occur where a small number of organizational processes predominate, i.e., over small spatial extents and regions exhibiting strong environmental gradients. ?? Springer-Verlag 2004.

  20. Spatial and temporal relationships among watershed mining, water quality, and freshwater mussel status in an eastern USA river.

    PubMed

    Zipper, Carl E; Donovan, Patricia F; Jones, Jess W; Li, Jing; Price, Jennifer E; Stewart, Roger E

    2016-01-15

    The Powell River of southwestern Virginia and northeastern Tennessee, USA, drains a watershed with extensive coal surface mining, and it hosts exceptional biological richness, including at-risk species of freshwater mussels, downstream of mining-disturbed watershed areas. We investigated spatial and temporal patterns of watershed mining disturbance; their relationship to water quality change in the section of the river that connects mining areas to mussel habitat; and relationships of mining-related water constituents to measures of recent and past mussel status. Freshwater mussels in the Powell River have experienced significant declines over the past 3.5 decades. Over that same period, surface coal mining has influenced the watershed. Water-monitoring data collected by state and federal agencies demonstrate that dissolved solids and associated constituents that are commonly influenced by Appalachian mining (specific conductance, pH, hardness and sulfates) have experienced increasing temporal trends from the 1960s through ~2008; but, of those constituents, only dissolved solids concentrations are available widely within the Powell River since ~2008. Dissolved solids concentrations have stabilized in recent years. Dissolved solids, specific conductance, pH, and sulfates also exhibited spatial patterns that are consistent with dilution of mining influence with increasing distance from mined areas. Freshwater mussel status indicators are correlated negatively with dissolved solids concentrations, spatially and temporally, but the direct causal mechanisms responsible for mussel declines remain unknown. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. A comparison of regional and national values for recovering threatened and endangered marine species in the United States.

    PubMed

    Wallmo, Kristy; Lew, Daniel K

    2016-09-01

    It is generally acknowledged that willingness-to-pay (WTP) estimates for environmental goods exhibit some degree of spatial variation. In a policy context, spatial variation in threatened and endangered species values is important to understand, as the benefit stream from policies affecting threatened and endangered species may vary locally, regionally, or among certain population segments. In this paper we present WTP estimates for eight different threatened and endangered marine species estimated from a stated preference choice experiment. WTP is estimated at two different spatial scales: (a) a random sample of over 5000 U.S. households and (b) geographically embedded samples (relative to the U.S. household sample) of nine U.S. Census regions. We conduct region-to-region and region-to-nation statistical comparisons to determine whether species values differ among regions and between each region and the entire U.S. Our results show limited spatial variation between national values and values estimated from regionally embedded samples, and differences are only found for three of the eight species. More variation exists between regions, and for all species there is a significant difference in at least one region-to-region comparison. Given that policy analyses involving threatened and endangered marine species can often be regional in scope (e.g., ecosystem management) or may disparately affect different regions, our results should be of high interest to the marine management community. Published by Elsevier Ltd.

  2. Hippocampal damage impairs long-term spatial memory in rats: comparison between electrolytic and neurotoxic lesions.

    PubMed

    Ramos, Juan M J

    2008-03-18

    In previous studies we have suggested that the dorsal hippocampus is involved in spatial consolidation by showing that rats with electrolytic hippocampal lesions exhibit a profound deficit in the retention of an allocentric task 24 days after the acquisition. However, in various hippocampal-dependent tasks, several studies have shown an overestimation of the behavioral deficit when electrolytic versus axon-sparing cytotoxic lesions has been used. For this reason, in this report we compare the effects on spatial retention of electrolytic and neurotoxic lesions to the dorsal hippocampus. Results showed a similar deficit in spatial retention in both groups 24 days after acquisition. Thus, the hippocampus proper and not fibers of passage or extrahippocampal damage is directly responsible for the deficit in spatial retention seen in rats with electrolytic lesions.

  3. Rapamycin Effectively Impedes Melamine-Induced Impairments of Cognition and Synaptic Plasticity in Wistar Rats.

    PubMed

    Fu, Jingxuan; Wang, Hui; Gao, Jing; Yu, Mei; Wang, Rubin; Yang, Zhuo; Zhang, Tao

    2017-03-01

    Our previous investigation demonstrated that autophagy significantly reduced melamine-induced cell death in PC12 cells via inhibiting the excessive generation of ROS. In the present study, we further examine if rapamycin, used as an autophagy activator, can play a significant role in protecting neurons and alleviating the impairment of spatial cognition and hippocampal synaptic plasticity in melamine-treated rats. Male Wistar rats were divided into three groups: control, melamine-treated, and melamine-treated + rapamycin. The animal model was established by administering melamine at a dose of 300 mg/kg/day for 4 weeks. Rapamycin was intraperitoneally given at a dose of 1 mg/kg/day for 28 consecutive days. The Morris water maze test showed that spatial learning and reversal learning in melamine-treated rats were considerably damaged, whereas rapamycin significantly impeded the cognitive function impairment. Rapamycin efficiently alleviated the melamine-induced impairments of both long-term potentiation (LTP) and depotentiation, which were damaged in melamine rats. Rapamycin further increased the expression level of autophagy markers, which were significantly enhanced in melamine rats. Moreover, rapamycin noticeably decreased the reactive oxygen species level, while the superoxide dismutase activity was remarkably increased by rapamycin in melamine rats. Malondialdehyde assay exhibited that rapamycin prominently reduced the malondialdehyde (MDA) level of hippocampal neurons in melamine-treated rats. In addition, rapamycin significantly decreased the caspase-3 activity, which was elevated by melamine. Consequently, our results suggest that regulating autophagy may become a new targeted therapy to relieve the damage induced by melamine.

  4. Changes in daily and monthly rainfall in the Middle Yellow River, China

    NASA Astrophysics Data System (ADS)

    He, Yi; Tian, Peng; Mu, Xingmin; Gao, Peng; Zhao, Guangju; Wang, Fei; Li, Pengfei

    2017-07-01

    Highly concentrated precipitation, where a large percentage of annual precipitation occurs over a few days, may include a high risk of flooding and severe soil erosion. Thus, areas with severe erosion such as the Loess Plateau in China are particularly vulnerable to highly concentrated precipitation events due to climate change. In this study, we investigated spatial and temporal patterns in the concentration of rainfall in the Middle Yellow River (MYR) from the last 56 years (1958-2013). We used daily and monthly precipitation data from 26 meteorological stations in the study area to calculate the precipitation concentration index (PCI) and the concentration index (CI). The southern and northern parts of the MYR were characterized by a lower CI with a decreasing trend, while the middle parts had a higher CI with an increasing trend. High PCI values occurred in the southern MYR, while lower PCIs with a more homogenous rainfall distribution were found mainly in the northern parts of the MYR. The annual PCI and CI exhibited positive trends at most stations, although only a minority of stations had significant trends ( P < 0.05). At seasonal scales, CI exhibited significantly increasing trends in winter at most stations, while a few stations had significant trends in the other three seasons. These findings provide important reference information to facilitate ecological restoration and farming operations in the study region.

  5. Hot Spots and Hot Times: Wildlife Road Mortality in a Regional Conservation Corridor.

    PubMed

    Garrah, Evelyn; Danby, Ryan K; Eberhardt, Ewen; Cunnington, Glenn M; Mitchell, Scott

    2015-10-01

    Strategies to reduce wildlife road mortality have become a significant component of many conservation efforts. However, their success depends on knowledge of the temporal and spatial patterns of mortality. We studied these patterns along the 1000 Islands Parkway in Ontario, Canada, a 37 km road that runs adjacent to the St. Lawrence River and bisects the Algonquin-to-Adirondacks international conservation corridor. Characteristics of all vertebrate road kill were recorded during 209 bicycle surveys conducted from 2008 to 2011. We estimate that over 16,700 vertebrates are killed on the road from April to October each year; most are amphibians, but high numbers of birds, mammals, and reptiles were also found, including six reptiles considered at-risk in Canada. Regression tree analysis was used to assess the importance of seasonality, weather, and traffic on road kill magnitude. All taxa except mammals exhibited distinct temporal peaks corresponding to phases in annual life cycles. Variations in weather and traffic were only important outside these peak times. Getis-Ord analysis was used to identify spatial clusters of mortality. Hot spots were found in all years for all taxa, but locations varied annually. A significant spatial association was found between multiyear hot spots and wetlands. The results underscore the notion that multi-species conservation efforts must account for differences in the seasonality of road mortality among species and that multiple years of data are necessary to identify locations where the greatest conservation good can be achieved. This information can be used to inform mitigation strategies with implications for conservation at regional scales.

  6. Evaluation of wildfire patterns at the wildland-urban fringe across the continental U.S.

    NASA Astrophysics Data System (ADS)

    Kinoshita, A. M.; Hogue, T. S.

    2014-12-01

    Wildfires threaten ecosystems and urban development across the United States, posing significant implications for land management and natural processes such as watershed hydrology. This study investigates the spatial association between large wildfires and urbanization. Several geospatial dataset are combined to map wildfires (Monitoring Trends in Burn Severity for 1984 to 2012) and housing density (SILVIS Lab Spatial Analysis for Conservation and Sustainability decadal housing density for 1940 to 2030) relative to natural wildlands across the contiguous U.S. Several buffers (i.e. 25 km) are developed around wildlands (Protected Areas Database of the United States) to quantify the change and relationship in spatial fire and housing density patterns. Since 1984, wildfire behavior is cyclical and follows general climatology, where warmer years have more and larger fires. Ignition locations also follow transportation corridors and development which provide easy accessibility to wildlands. In California, both fire frequency and total acres burned exhibit increasing trends (statistically significant at 95%). The 1980s average wildfire frequency and total acres burned was 3100 fires and approximately 1200 km2, respectively. These numbers have increased to 2200 fires and over 1500 km2 in the 2010 to 2012 period alone. Initial observations also show that decennial population and area burned for four major Californian counties (Los Angeles, San Bernardino, San Diego, and Shasta) show strong correlation between the last decade of burned area, urban-fringe proximity, and urbanization trends. Improving our understanding of human induced wildfire regimes provides key information on urban fringe communities most vulnerable to the wildfire risks and can help inform regional development planning.

  7. Relationship between selected orientation rest frame, circular vection and space motion sickness

    NASA Technical Reports Server (NTRS)

    Harm, D. L.; Parker, D. E.; Reschke, M. F.; Skinner, N. C.

    1998-01-01

    Space motion sickness (SMS) and spatial orientation and motion perception disturbances occur in 70-80% of astronauts. People select "rest frames" to create the subjective sense of spatial orientation. In microgravity, the astronaut's rest frame may be based on visual scene polarity cues and on the internal head and body z axis (vertical body axis). The data reported here address the following question: Can an astronaut's orientation rest frame be related and described by other variables including circular vection response latencies and space motion sickness? The astronaut's microgravity spatial orientation rest frames were determined from inflight and postflight verbal reports. Circular vection responses were elicited by rotating a virtual room continuously at 35 degrees/s in pitch, roll and yaw with respect to the astronaut. Latency to the onset of vection was recorded from the time the crew member opened their eyes to the onset of vection. The astronauts who used visual cues exhibited significantly shorter vection latencies than those who used internal z axis cues. A negative binomial regression model was used to represent the observed total SMS symptom scores for each subject for each flight day. Orientation reference type had a significant effect, resulting in an estimated three-fold increase in the expected motion sickness score on flight day 1 for astronauts who used visual cues. The results demonstrate meaningful classification of astronauts' rest frames and their relationships to sensitivity to circular vection and SMS. Thus, it may be possible to use vection latencies to predict SMS severity and duration.

  8. Cysteamine treatment ameliorates alterations in GAD67 expression and spatial memory in heterozygous reeler mice

    PubMed Central

    Kutiyanawalla, Ammar; Promsote, Wanwisa; Terry, Alvin; Pillai, Anilkumar

    2011-01-01

    Brain derived neurotrophic factor (BDNF) signaling through its receptor, TrkB is known to regulate GABAergic function and glutamic acid decarboxylase (GAD) 67 expression in neurons. Alterations in BDNF signaling have been implicated in the pathophysiology of schizophrenia and as a result, they are a potential therapeutic target. Interestingly, heterozygous reeler mice (HRM) have decreased GAD67 expression in the frontal cortex and hippocampus and they exhibit many behavioral and neurochemical abnormalities similar to schizophrenia. In the present study, we evaluated the potential of cysteamine, a neuroprotective compound to improve the deficits in GAD67 expression and cognitive function in HRM. We found that cysteamine administration (150 mg/kg/day, through drinking water) for 30 days significantly ameliorated the decreases in GAD67, mature BDNF and full-length TrkB protein levels found in frontal cortex and hippocampus of HRM. A significant attenuation of the increased levels of truncated BDNF in frontal cortex and hippocampus, as well as truncated TrkB in frontal cortex of HRM was also observed following cysteamine treatment. In behavioral studies, HRM were impaired in a Y-maze spatial recognition memory task, but not in a spontaneous alternation task or a sensorimotor, prepulse inhibition (PPI) procedure. Cysteamine improved Y-maze spatial recognition in HRM to the level of wide-type controls and it improved PPI in both wild-type and HRM. Finally, mice deficient in TrkB, showed a reduced response to cysteamine in GAD67 expression suggesting that TrkB signaling plays an important role in GAD67 regulation by cysteamine. PMID:21777509

  9. Age-Related Memory Impairment Associated With Decreased Endogenous Estradiol in the Hippocampus of Female Rats.

    PubMed

    Chamniansawat, Siriporn; Sawatdiyaphanon, Chattraporn

    It is widely known that not only the gonadal estradiol (E2) but also hippocampal E2 plays an essential role in memory process. However, the role of hippocampal E2-enhanced memory mechanism during aging is largely unknown. The aim of the present study was to investigate the effect of age on E2 concentration, the expression level of its receptors, and key steroidogenic enzymes in hippocampus. We also investigated the effect of microglia activation on E2 synthesis in hippocampal neurons. The results showed that serum E2 was higher in 19-month-old (aged) rats, which exhibited spatial memory decline in the Morris water maze (MWM) test when compared to the younger rats. Hence, serum E2 may not be associated with the reduced spatial memory performance in aging. In contrast, the level of E2 and the expressions of its receptors were significantly decreased in hippocampus of aged female rat compared to younger females. Furthermore, the expressions of key hippocampal steroidogenic enzymes, steroidogenic acute regulatory protein (StAR), and cytochrome P450 (P450) also significantly decreased with age, which resulted in lower hippocampal E2 levels. In addition, we found that the microglia of aged brain highly expressed interleukin 6 (IL-6), which directly inhibited E2 synthesis in hippocampal neurons via suppression of P450 synthesis. Taken together, we summarized that the microglia-derived IL-6 inhibited hippocampal E2 synthesis in aged rats which, in turn, contributed to the deficit of spatial memory performance.

  10. Hot Spots and Hot Times: Wildlife Road Mortality in a Regional Conservation Corridor

    NASA Astrophysics Data System (ADS)

    Garrah, Evelyn; Danby, Ryan K.; Eberhardt, Ewen; Cunnington, Glenn M.; Mitchell, Scott

    2015-10-01

    Strategies to reduce wildlife road mortality have become a significant component of many conservation efforts. However, their success depends on knowledge of the temporal and spatial patterns of mortality. We studied these patterns along the 1000 Islands Parkway in Ontario, Canada, a 37 km road that runs adjacent to the St. Lawrence River and bisects the Algonquin-to-Adirondacks international conservation corridor. Characteristics of all vertebrate road kill were recorded during 209 bicycle surveys conducted from 2008 to 2011. We estimate that over 16,700 vertebrates are killed on the road from April to October each year; most are amphibians, but high numbers of birds, mammals, and reptiles were also found, including six reptiles considered at-risk in Canada. Regression tree analysis was used to assess the importance of seasonality, weather, and traffic on road kill magnitude. All taxa except mammals exhibited distinct temporal peaks corresponding to phases in annual life cycles. Variations in weather and traffic were only important outside these peak times. Getis-Ord analysis was used to identify spatial clusters of mortality. Hot spots were found in all years for all taxa, but locations varied annually. A significant spatial association was found between multiyear hot spots and wetlands. The results underscore the notion that multi-species conservation efforts must account for differences in the seasonality of road mortality among species and that multiple years of data are necessary to identify locations where the greatest conservation good can be achieved. This information can be used to inform mitigation strategies with implications for conservation at regional scales.

  11. Loss of Hippocampal Neurons after Kainate Treatment Correlates with Behavioral Deficits

    PubMed Central

    Maia, Gisela H.; Quesado, José L.; Soares, Joana I.; do Carmo, Joana M.; Andrade, Pedro A.; Andrade, José P.; Lukoyanov, Nikolai V.

    2014-01-01

    Treating rats with kainic acid induces status epilepticus (SE) and leads to the development of behavioral deficits and spontaneous recurrent seizures later in life. However, in a subset of rats, kainic acid treatment does not induce overt behaviorally obvious acute SE. The goal of this study was to compare the neuroanatomical and behavioral changes induced by kainate in rats that developed convulsive SE to those who did not. Adult male Wistar rats were treated with kainic acid and tested behaviorally 5 months later. Rats that had experienced convulsive SE showed impaired performance on the spatial water maze and passive avoidance tasks, and on the context and tone retention tests following fear conditioning. In addition, they exhibited less anxiety-like behaviors than controls on the open-field and elevated plus-maze tests. Histologically, convulsive SE was associated with marked neuron loss in the hippocampal CA3 and CA1 fields, and in the dentate hilus. Rats that had not experienced convulsive SE after kainate treatment showed less severe, but significant impairments on the spatial water maze and passive avoidance tasks. These rats had fewer neurons than control rats in the dentate hilus, but not in the hippocampal CA3 and CA1 fields. Correlational analyses revealed significant relationships between spatial memory indices of rats and neuronal numbers in the dentate hilus and CA3 pyramidal field. These results show that a part of the animals that do not display intense behavioral seizures (convulsive SE) immediately after an epileptogenic treatment, later in life, they may still have noticeable structural and functional changes in the brain. PMID:24409306

  12. Identification of an intact ParaHox cluster with temporal colinearity but altered spatial colinearity in the hemichordate Ptychodera flava

    PubMed Central

    2013-01-01

    Background ParaHox and Hox genes are thought to have evolved from a common ancestral ProtoHox cluster or from tandem duplication prior to the divergence of cnidarians and bilaterians. Similar to Hox clusters, chordate ParaHox genes including Gsx, Xlox, and Cdx, are clustered and their expression exhibits temporal and spatial colinearity. In non-chordate animals, however, studies on the genomic organization of ParaHox genes are limited to only a few animal taxa. Hemichordates, such as the Enteropneust acorn worms, have been used to gain insights into the origins of chordate characters. In this study, we investigated the genomic organization and expression of ParaHox genes in the indirect developing hemichordate acorn worm Ptychodera flava. Results We found that P. flava contains an intact ParaHox cluster with a similar arrangement to that of chordates. The temporal expression order of the P. flava ParaHox genes is the same as that of the chordate ParaHox genes. During embryogenesis, the spatial expression pattern of PfCdx in the posterior endoderm represents a conserved feature similar to the expression of its orthologs in other animals. On the other hand, PfXlox and PfGsx show a novel expression pattern in the blastopore. Nevertheless, during metamorphosis, PfXlox and PfCdx are expressed in the endoderm in a spatially staggered pattern similar to the situation in chordates. Conclusions Our study shows that P. flava ParaHox genes, despite forming an intact cluster, exhibit temporal colinearity but lose spatial colinearity during embryogenesis. During metamorphosis, partial spatial colinearity is retained in the transforming larva. These results strongly suggest that intact ParaHox gene clustering was retained in the deuterostome ancestor and is correlated with temporal colinearity. PMID:23802544

  13. Regularization design for high-quality cone-beam CT of intracranial hemorrhage using statistical reconstruction

    NASA Astrophysics Data System (ADS)

    Dang, H.; Stayman, J. W.; Xu, J.; Sisniega, A.; Zbijewski, W.; Wang, X.; Foos, D. H.; Aygun, N.; Koliatsos, V. E.; Siewerdsen, J. H.

    2016-03-01

    Intracranial hemorrhage (ICH) is associated with pathologies such as hemorrhagic stroke and traumatic brain injury. Multi-detector CT is the current front-line imaging modality for detecting ICH (fresh blood contrast 40-80 HU, down to 1 mm). Flat-panel detector (FPD) cone-beam CT (CBCT) offers a potential alternative with a smaller scanner footprint, greater portability, and lower cost potentially well suited to deployment at the point of care outside standard diagnostic radiology and emergency room settings. Previous studies have suggested reliable detection of ICH down to 3 mm in CBCT using high-fidelity artifact correction and penalized weighted least-squared (PWLS) image reconstruction with a post-artifact-correction noise model. However, ICH reconstructed by traditional image regularization exhibits nonuniform spatial resolution and noise due to interaction between the statistical weights and regularization, which potentially degrades the detectability of ICH. In this work, we propose three regularization methods designed to overcome these challenges. The first two compute spatially varying certainty for uniform spatial resolution and noise, respectively. The third computes spatially varying regularization strength to achieve uniform "detectability," combining both spatial resolution and noise in a manner analogous to a delta-function detection task. Experiments were conducted on a CBCT test-bench, and image quality was evaluated for simulated ICH in different regions of an anthropomorphic head. The first two methods improved the uniformity in spatial resolution and noise compared to traditional regularization. The third exhibited the highest uniformity in detectability among all methods and best overall image quality. The proposed regularization provides a valuable means to achieve uniform image quality in CBCT of ICH and is being incorporated in a CBCT prototype for ICH imaging.

  14. Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.

    PubMed

    Spagnolo, Daniel M; Gyanchandani, Rekha; Al-Kofahi, Yousef; Stern, Andrew M; Lezon, Timothy R; Gough, Albert; Meyer, Dan E; Ginty, Fiona; Sarachan, Brion; Fine, Jeffrey; Lee, Adrian V; Taylor, D Lansing; Chennubhotla, S Chakra

    2016-01-01

    Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to heterogeneity. We demonstrate how to quantify spatial heterogeneity from immunofluorescence pathology samples, using a set of 3 basic breast cancer biomarkers as a test case. We learn a set of dominant biomarker intensity patterns and map the spatial distribution of the biomarker patterns with a network. We then describe the pairwise association statistics for each pattern within the network using pointwise mutual information (PMI) and visually represent heterogeneity with a two-dimensional map. We found a salient set of 8 biomarker patterns to describe cellular phenotypes from a tissue microarray cohort containing 4 different breast cancer subtypes. After computing PMI for each pair of biomarker patterns in each patient and tumor replicate, we visualize the interactions that contribute to the resulting association statistics. Then, we demonstrate the potential for using PMI as a diagnostic biomarker, by comparing PMI maps and heterogeneity scores from patients across the 4 different cancer subtypes. Estrogen receptor positive invasive lobular carcinoma patient, AL13-6, exhibited the highest heterogeneity score among those tested, while estrogen receptor negative invasive ductal carcinoma patient, AL13-14, exhibited the lowest heterogeneity score. This paper presents an approach for describing intratumor heterogeneity, in a quantitative fashion (via PMI), which departs from the purely qualitative approaches currently used in the clinic. PMI is generalizable to highly multiplexed/hyperplexed immunofluorescence images, as well as spatial data from complementary in situ methods including FISSEQ and CyTOF, sampling many different components within the TME. We hypothesize that PMI will uncover key spatial interactions in the TME that contribute to disease proliferation and progression.

  15. Space-time quantitative source apportionment of soil heavy metal concentration increments.

    PubMed

    Yang, Yong; Christakos, George; Guo, Mingwu; Xiao, Lu; Huang, Wei

    2017-04-01

    Assessing the space-time trends and detecting the sources of heavy metal accumulation in soils have important consequences in the prevention and treatment of soil heavy metal pollution. In this study, we collected soil samples in the eastern part of the Qingshan district, Wuhan city, Hubei Province, China, during the period 2010-2014. The Cd, Cu, Pb and Zn concentrations in soils exhibited a significant accumulation during 2010-2014. The spatiotemporal Kriging technique, based on a quantitative characterization of soil heavy metal concentration variations in terms of non-separable variogram models, was employed to estimate the spatiotemporal soil heavy metal distribution in the study region. Our findings showed that the Cd, Cu, and Zn concentrations have an obvious incremental tendency from the southwestern to the central part of the study region. However, the Pb concentrations exhibited an obvious tendency from the northern part to the central part of the region. Then, spatial overlay analysis was used to obtain absolute and relative concentration increments of adjacent 1- or 5-year periods during 2010-2014. The spatial distribution of soil heavy metal concentration increments showed that the larger increments occurred in the center of the study region. Lastly, the principal component analysis combined with the multiple linear regression method were employed to quantify the source apportionment of the soil heavy metal concentration increments in the region. Our results led to the conclusion that the sources of soil heavy metal concentration increments should be ascribed to industry, agriculture and traffic. In particular, 82.5% of soil heavy metal concentration increment during 2010-2014 was ascribed to industrial/agricultural activities sources. Using STK and SOA to obtain the spatial distribution of heavy metal concentration increments in soils. Using PCA-MLR to quantify the source apportionment of soil heavy metal concentration increments. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. A Mouse Model of Visual Perceptual Learning Reveals Alterations in Neuronal Coding and Dendritic Spine Density in the Visual Cortex.

    PubMed

    Wang, Yan; Wu, Wei; Zhang, Xian; Hu, Xu; Li, Yue; Lou, Shihao; Ma, Xiao; An, Xu; Liu, Hui; Peng, Jing; Ma, Danyi; Zhou, Yifeng; Yang, Yupeng

    2016-01-01

    Visual perceptual learning (VPL) can improve spatial vision in normally sighted and visually impaired individuals. Although previous studies of humans and large animals have explored the neural basis of VPL, elucidation of the underlying cellular and molecular mechanisms remains a challenge. Owing to the advantages of molecular genetic and optogenetic manipulations, the mouse is a promising model for providing a mechanistic understanding of VPL. Here, we thoroughly evaluated the effects and properties of VPL on spatial vision in C57BL/6J mice using a two-alternative, forced-choice visual water task. Briefly, the mice underwent prolonged training at near the individual threshold of contrast or spatial frequency (SF) for pattern discrimination or visual detection for 35 consecutive days. Following training, the contrast-threshold trained mice showed an 87% improvement in contrast sensitivity (CS) and a 55% gain in visual acuity (VA). Similarly, the SF-threshold trained mice exhibited comparable and long-lasting improvements in VA and significant gains in CS over a wide range of SFs. Furthermore, learning largely transferred across eyes and stimulus orientations. Interestingly, learning could transfer from a pattern discrimination task to a visual detection task, but not vice versa. We validated that this VPL fully restored VA in adult amblyopic mice and old mice. Taken together, these data indicate that mice, as a species, exhibit reliable VPL. Intrinsic signal optical imaging revealed that mice with perceptual training had higher cut-off SFs in primary visual cortex (V1) than those without perceptual training. Moreover, perceptual training induced an increase in the dendritic spine density in layer 2/3 pyramidal neurons of V1. These results indicated functional and structural alterations in V1 during VPL. Overall, our VPL mouse model will provide a platform for investigating the neurobiological basis of VPL.

  17. Methodological Caveats in the Detection of Coordinated Replay between Place Cells and Grid Cells

    PubMed Central

    Trimper, John B.; Trettel, Sean G.; Hwaun, Ernie; Colgin, Laura Lee

    2017-01-01

    At rest, hippocampal “place cells,” neurons with receptive fields corresponding to specific spatial locations, reactivate in a manner that reflects recently traveled trajectories. These “replay” events have been proposed as a mechanism underlying memory consolidation, or the transfer of a memory representation from the hippocampus to neocortical regions associated with the original sensory experience. Accordingly, it has been hypothesized that hippocampal replay of a particular experience should be accompanied by simultaneous reactivation of corresponding representations in the neocortex and in the entorhinal cortex, the primary interface between the hippocampus and the neocortex. Recent studies have reported that coordinated replay may occur between hippocampal place cells and medial entorhinal cortex grid cells, cells with multiple spatial receptive fields. Assessing replay in grid cells is problematic, however, as the cells exhibit regularly spaced spatial receptive fields in all environments and, therefore, coordinated replay between place cells and grid cells may be detected by chance. In the present report, we adapted analytical approaches utilized in recent studies of grid cell and place cell replay to determine the extent to which coordinated replay is spuriously detected between grid cells and place cells recorded from separate rats. For a subset of the employed analytical methods, coordinated replay was detected spuriously in a significant proportion of cases in which place cell replay events were randomly matched with grid cell firing epochs of equal duration. More rigorous replay evaluation procedures and minimum spike count requirements greatly reduced the amount of spurious findings. These results provide insights into aspects of place cell and grid cell activity during rest that contribute to false detection of coordinated replay. The results further emphasize the need for careful controls and rigorous methods when testing the hypothesis that place cells and grid cells exhibit coordinated replay. PMID:28824388

  18. Glia protein aquaporin-4 regulates aversive motivation of spatial memory in Morris water maze.

    PubMed

    Zhang, Ji; Li, Ying; Chen, Zhong-Guo; Dang, Hui; Ding, Jian-Hua; Fan, Yi; Hu, Gang

    2013-12-01

    Although extensive investigation has revealed that an astrocyte-specific protein aquaporin-4 (AQP4) participates in regulating synaptic plasticity and memory, a functional relationship between AQP4 and learning processing has not been clearly established. This study was designed to test our hypothesis that AQP4 modulates the aversive motivation in Morris water maze (MWM). Using hidden platform training, we observed that AQP4 KO mice significantly decreased their swimming velocity compared with wild-type (WT) mice. To test for a relationship between velocities and escape motivation, we removed the platform and subjected a new group of mice similar to the session of hidden platform training. We found that KO mice exhibited a gradual reduction in swimming velocity, while WT mice did not alter their velocity. In the subsequent probe trial, KO mice after no platform training significantly decreased their mean velocity compared with those KO mice after hide platform training. However, all of KO mice were not impaired in their ability to locate a visible, cued escape platform. Our findings, along with a previous report that AQP4 regulates memory consolidation, implicate a novel role for this glial protein in modulating the aversive motivation in spatial learning paradigm. © 2013 John Wiley & Sons Ltd.

  19. A comparison of recharge rates in aquifers of the United States based on groundwater-age data

    USGS Publications Warehouse

    McMahon, P.B.; Plummer, Niel; Böhlke, J.K.; Shapiro, S.D.; Hinkle, S.R.

    2011-01-01

    An overview is presented of existing groundwater-age data and their implications for assessing rates and timescales of recharge in selected unconfined aquifer systems of the United States. Apparent age distributions in aquifers determined from chlorofluorocarbon, sulfur hexafluoride, tritium/helium-3, and radiocarbon measurements from 565 wells in 45 networks were used to calculate groundwater recharge rates. Timescales of recharge were defined by 1,873 distributed tritium measurements and 102 radiocarbon measurements from 27 well networks. Recharge rates ranged from < 10 to 1,200 mm/yr in selected aquifers on the basis of measured vertical age distributions and assuming exponential age gradients. On a regional basis, recharge rates based on tracers of young groundwater exhibited a significant inverse correlation with mean annual air temperature and a significant positive correlation with mean annual precipitation. Comparison of recharge derived from groundwater ages with recharge derived from stream base-flow evaluation showed similar overall patterns but substantial local differences. Results from this compilation demonstrate that age-based recharge estimates can provide useful insights into spatial and temporal variability in recharge at a national scale and factors controlling that variability. Local age-based recharge estimates provide empirical data and process information that are needed for testing and improving more spatially complete model-based methods.

  20. A tale of two seas: contrasting patterns of population structure in the small-spotted catshark across Europe

    PubMed Central

    Gubili, Chrysoula; Sims, David W.; Veríssimo, Ana; Domenici, Paolo; Ellis, Jim; Grigoriou, Panagiotis; Johnson, Andrew F.; McHugh, Matthew; Neat, Francis; Satta, Andrea; Scarcella, Giuseppe; Serra-Pereira, Bárbara; Soldo, Alen; Genner, Martin J.; Griffiths, Andrew M.

    2014-01-01

    Elasmobranchs represent important components of marine ecosystems, but they can be vulnerable to overexploitation. This has driven investigations into the population genetic structure of large-bodied pelagic sharks, but relatively little is known of population structure in smaller demersal taxa, which are perhaps more representative of the biodiversity of the group. This study explores spatial population genetic structure of the small-spotted catshark (Scyliorhinus canicula), across European seas. The results show significant genetic differences among most of the Mediterranean sample collections, but no significant structure among Atlantic shelf areas. The data suggest the Mediterranean populations are likely to have persisted in a stable and structured environment during Pleistocene sea-level changes. Conversely, the Northeast Atlantic populations would have experienced major changes in habitat availability during glacial cycles, driving patterns of population reduction and expansion. The data also provide evidence of male-biased dispersal and female philopatry over large spatial scales, implying complex sex-determined differences in the behaviour of elasmobranchs. On the basis of this evidence, we suggest that patterns of connectivity are determined by trends of past habitat stability that provides opportunity for local adaptation in species exhibiting philopatric behaviour, implying that resilience of populations to fisheries and other stressors may differ across the range of species. PMID:26064555

  1. Marine cyanophages exhibit local and regional biogeography.

    PubMed

    Marston, Marcia F; Taylor, Samantha; Sme, Noel; Parsons, Rachel J; Noyes, Timothy J E; Martiny, Jennifer B H

    2013-05-01

    Biogeographic patterns have been demonstrated for a wide range of microorganisms. Nevertheless, the biogeography of marine viruses has been slower to emerge. Here we investigate biogeographic patterns of marine cyanophages that infect Synechococcus sp. WH7803 across multiple spatial and temporal scales. We compared cyanophage myoviral communities from nine coastal sites in Southern New England (SNE), USA, one site in Long Island NY, and four sites from Bermuda's inshore waters by assaying cyanophage isolates using the myoviral g43 DNA polymerase gene. Cyanophage community composition varied temporally at each of the sites. Further, 6 years of sampling at one Narragansett Bay site revealed annual seasonal variations in community composition, driven by the seasonal reoccurrence of specific viral taxa. Although the four Bermuda communities were similar to one another, they were significantly different than the North American coastal communities, with almost no overlap of taxa between the two regions. Among the SNE sites, cyanophage community composition also varied significantly and was correlated with the body of water sampled (e.g. Narragansett Bay, Cape Cod Bay, Vineyard Sound), although here, the same viral taxa were found at multiple sites. This study demonstrates that marine cyanophages display striking seasonal and spatial biogeographic patterns. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  2. Relationship among land surface temperature and LUCC, NDVI in typical karst area.

    PubMed

    Deng, Yuanhong; Wang, Shijie; Bai, Xiaoyong; Tian, Yichao; Wu, Luhua; Xiao, Jianyong; Chen, Fei; Qian, Qinghuan

    2018-01-12

    Land surface temperature (LST) can reflect the land surface water-heat exchange process comprehensively, which is considerably significant to the study of environmental change. However, research about LST in karst mountain areas with complex topography is scarce. Therefore, we retrieved the LST in a karst mountain area from Landsat 8 data and explored its relationships with LUCC and NDVI. The results showed that LST of the study area was noticeably affected by altitude and underlying surface type. In summer, abnormal high-temperature zones were observed in the study area, perhaps due to karst rocky desertification. LSTs among different land use types significantly differed with the highest in construction land and the lowest in woodland. The spatial distributions of NDVI and LST exhibited opposite patterns. Under the spatial combination of different land use types, the LST-NDVI feature space showed an obtuse-angled triangle shape and showed a negative linear correlation after removing water body data. In summary, the LST can be retrieved well by the atmospheric correction model from Landsat 8 data. Moreover, the LST of the karst mountain area is controlled by altitude, underlying surface type and aspect. This study provides a reference for land use planning, ecological environment restoration in karst areas.

  3. The spatial distribution of cropland carbon transfer in Jilin province during 2014

    NASA Astrophysics Data System (ADS)

    Cai, Xintong; Meng, Jian; Li, Qiuhui; Gao, Shuang; Zhu, Xianjin

    2018-01-01

    Cropland carbon transfer (CCT, gC yr-1) is an important component in the carbon budget of terrestrial ecosystems. Analyzing the value of CCT and its spatial variation would provide a data basis for assessing the regional carbon balance. Based on the data from Jilin statistical yearbook 2015, we investigated the spatial variation of CCT in Jilin province during 2014. Results suggest that the CCT of Jilin province was 30.83 TgC, which exhibited a decreasing trend from the centre to the border but the west side was higher than the east. The magnitude of carbon transfer per area (MCT), which showed a similar spatial distribution with CCT, was the dominating component of CCT spatial distribution. The spatial distribution of MCT was jointly affected by that of the ratio of planting area to regional area (RPR) and carbon transfer per planting area (CTP), where RPR and CTP contributed 65.55% and 34.5% of MCT spatial distribution, respectively. Therefore, CCT in Jilin province spatially varied, which made it highly needed to consider the difference in CCT among regions when we assessing the regional carbon budget.

  4. Rapamycin restores BDNF-LTP and the persistence of long-term memory in a model of Down's syndrome.

    PubMed

    Andrade-Talavera, Yuniesky; Benito, Itziar; Casañas, Juan José; Rodríguez-Moreno, Antonio; Montesinos, María Luz

    2015-10-01

    Down's syndrome (DS) is the most prevalent genetic intellectual disability. Memory deficits significantly contribute to the cognitive dysfunction in DS. Previously, we discovered that mTOR-dependent local translation, a pivotal process for some forms of synaptic plasticity, is deregulated in a DS mouse model. Here, we report that these mice exhibit deficits in both synaptic plasticity (i.e., BDNF-long term potentiation) and the persistence of spatial long-term memory. Interestingly, these deficits were fully reversible using rapamycin, a Food and Drug Administration-approved specific mTOR inhibitor; therefore, rapamycin may be a novel pharmacotherapy to improve cognition in DS. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Lingda; Hayes, Ari; Song, Shuaiwen

    Modern GPUs employ cache to improve memory system efficiency. However, large amount of cache space is underutilized due to irregular memory accesses and poor spatial locality which exhibited commonly in GPU applications. Our experiments show that using smaller cache lines could improve cache space utilization, but it also frequently suffers from significant performance loss by introducing large amount of extra cache requests. In this work, we propose a novel cache design named tag-split cache (TSC) that enables fine-grained cache storage to address the problem of cache space underutilization while keeping memory request number unchanged. TSC divides tag into two partsmore » to reduce storage overhead, and it supports multiple cache line replacement in one cycle.« less

  6. Demonstration of Hadoop-GIS: A Spatial Data Warehousing System Over MapReduce

    PubMed Central

    Aji, Ablimit; Sun, Xiling; Vo, Hoang; Liu, Qioaling; Lee, Rubao; Zhang, Xiaodong; Saltz, Joel; Wang, Fusheng

    2016-01-01

    The proliferation of GPS-enabled devices, and the rapid improvement of scientific instruments have resulted in massive amounts of spatial data in the last decade. Support of high performance spatial queries on large volumes data has become increasingly important in numerous fields, which requires a scalable and efficient spatial data warehousing solution as existing approaches exhibit scalability limitations and efficiency bottlenecks for large scale spatial applications. In this demonstration, we present Hadoop-GIS – a scalable and high performance spatial query system over MapReduce. Hadoop-GIS provides an efficient spatial query engine to process spatial queries, data and space based partitioning, and query pipelines that parallelize queries implicitly on MapReduce. Hadoop-GIS also provides an expressive, SQL-like spatial query language for workload specification. We will demonstrate how spatial queries are expressed in spatially extended SQL queries, and submitted through a command line/web interface for execution. Parallel to our system demonstration, we explain the system architecture and details on how queries are translated to MapReduce operators, optimized, and executed on Hadoop. In addition, we will showcase how the system can be used to support two representative real world use cases: large scale pathology analytical imaging, and geo-spatial data warehousing. PMID:27617325

  7. Lambert-Amery

    Atmospheric Science Data Center

    2013-04-16

    ... exhibiting insufficient spatial contrast for stereoscopic retrieval are shown in dark gray. Clouds are apparent as a result of their ... their distributions, and retrieval of their heights provide information that will help to reduce this uncertainty. The Multi-angle ...

  8. Note: Development of a multichannel magnetic probe array for magnetohydrodynamic activity studies in Sino-United Spherical Tokamak

    NASA Astrophysics Data System (ADS)

    Zhong, H.; Tan, Y.; Gao, Z.

    2018-02-01

    A 30-channel movable magnetic probe radial array measuring the poloidal magnetic field's time derivative B˙ θ has been developed and installed on the Sino-United Spherical Tokamak to investigate the magnetohydrodynamic (MHD) activities in ohmic discharges. The probe array consists of thirty identical commercial chip inductors mounted on a slim printed circuit board and shielded by a customized quartz tube of 14 mm in outer diameter. With the application of instrumentation amplifiers, the system exhibits a good signal to noise ratio and the measured vertical field spatial distribution agrees well with the simulation result. The measured spatial and temporal distribution of B˙ θ during the MHD activities exhibits a clear phase reversal layer, which is a direct proof of tearing mode and provides a reliable indication of the magnetic island chain position.

  9. Spatially localized convection in a rotating layer

    NASA Astrophysics Data System (ADS)

    Knobloch, Edgar; Beaume, Cedric; Bergeon, Alain; Kao, Hsien-Ching

    2014-11-01

    We study two-dimensional stationary convection in a horizontal fluid layer heated from below and rotating about the vertical. With stress-free boundary conditions at top and bottom, spatially localized states can be found that are embedded in a self-generated background shear zone and lie on a pair of intertwined solution branches exhibiting ``slanted snaking.'' States of this type are present even in the absence of bistability between conduction and periodic convection - a consequence of the conservation of zonal momentum. With no-slip boundary conditions this quantity is no longer conserved but localized states continue to exist. These are no longer embedded in a background shear zone and exhibit standard snaking. Homotopic continuation from free-slip to no-slip boundary conditions is used to track the changes in the properties of the solutions and the associated bifurcation diagrams.

  10. Incongruent genetic connectivity patterns for VME indicator taxa: implications for the management of New Zealand's vulnerable marine ecosystems

    NASA Astrophysics Data System (ADS)

    Clark, M. R.; Gardner, J.; Holland, L.; Zeng, C.; Hamilton, J. S.; Rowden, A. A.

    2016-02-01

    In the New Zealand region vulnerable marine ecosystems (VMEs) are at risk from commercial fishing activity and future seabed mining. Understanding connectivity among VMEs is important for the design of effective spatial management strategies, i.e. a network of protected areas. To date however, genetic connectivity in the New Zealand region has rarely been documented. As part of a project developing habitat suitability models and spatial management options for VMEs we used DNA sequence data and microsatellite genotyping to assess genetic connectivity for a range of VME indicator taxa, including the coral Desmophyllum dianthus, and the sponges Poecilastra laminaris and Penares palmatoclada. Overall, patterns of connectivity were inconsistent amonst taxa. Nonetheless, genetic data from each taxon were relevant to inform management at a variety of spatial scales. D. dianthus populations in the Kermadec volcanic arc and the Louisville Seamount Chain were indistinguishable, highlighting the importance of considering source-sink dynamics between populations beyond the EEZ in conservation planning. Poecilastra laminaris populations showed significant divergence across the Chatham Rise, in contrast to P. palmatoclada, which had a uniform haplotypic distribution. However, both sponge species exhibited the highest genetic diversity on the Chatham Rise, suggesting that this area is a genetic hotspot. The spatial heterogeneity of genetic patterns of structure suggest that inclusion of several taxa is necessary to facilitate understanding of regional connectivity patterns, variation in which may be attributed to alternate life history strategies, local hydrodynamic regimes, or in some cases, suboptimal sample sizes. Our findings provide important information for use by environmental managers, including summary maps of genetic diversity and barriers to gene flow, which will be used in spatial management decision-support tools.

  11. Generating Within-Plant Spatial Distributions of an Insect Herbivore Based on Aggregation Patterns and Per-Node Infestation Probabilities.

    PubMed

    Rincon, Diego F; Hoy, Casey W; Cañas, Luis A

    2015-04-01

    Most predator-prey models extrapolate functional responses from small-scale experiments assuming spatially uniform within-plant predator-prey interactions. However, some predators focus their search in certain plant regions, and herbivores tend to select leaves to balance their nutrient uptake and exposure to plant defenses. Individual-based models that account for heterogeneous within-plant predator-prey interactions can be used to scale-up functional responses, but they would require the generation of explicit prey spatial distributions within-plant architecture models. The silverleaf whitefly, Bemisia tabaci biotype B (Gennadius) (Hemiptera: Aleyrodidae), is a significant pest of tomato crops worldwide that exhibits highly aggregated populations at several spatial scales, including within the plant. As part of an analytical framework to understand predator-silverleaf whitefly interactions, the objective of this research was to develop an algorithm to generate explicit spatial counts of silverleaf whitefly nymphs within tomato plants. The algorithm requires the plant size and the number of silverleaf whitefly individuals to distribute as inputs, and includes models that describe infestation probabilities per leaf nodal position and the aggregation pattern of the silverleaf whitefly within tomato plants and leaves. The output is a simulated number of silverleaf whitefly individuals for each leaf and leaflet on one or more plants. Parameter estimation was performed using nymph counts per leaflet censused from 30 artificially infested tomato plants. Validation revealed a substantial agreement between algorithm outputs and independent data that included the distribution of counts of both eggs and nymphs. This algorithm can be used in simulation models that explore the effect of local heterogeneity on whitefly-predator dynamics. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Fine-Scale Analysis Reveals Cryptic Landscape Genetic Structure in Desert Tortoises

    PubMed Central

    Latch, Emily K.; Boarman, William I.; Walde, Andrew; Fleischer, Robert C.

    2011-01-01

    Characterizing the effects of landscape features on genetic variation is essential for understanding how landscapes shape patterns of gene flow and spatial genetic structure of populations. Most landscape genetics studies have focused on patterns of gene flow at a regional scale. However, the genetic structure of populations at a local scale may be influenced by a unique suite of landscape variables that have little bearing on connectivity patterns observed at broader spatial scales. We investigated fine-scale spatial patterns of genetic variation and gene flow in relation to features of the landscape in desert tortoise (Gopherus agassizii), using 859 tortoises genotyped at 16 microsatellite loci with associated data on geographic location, sex, elevation, slope, and soil type, and spatial relationship to putative barriers (power lines, roads). We used spatially explicit and non-explicit Bayesian clustering algorithms to partition the sample into discrete clusters, and characterize the relationships between genetic distance and ecological variables to identify factors with the greatest influence on gene flow at a local scale. Desert tortoises exhibit weak genetic structure at a local scale, and we identified two subpopulations across the study area. Although genetic differentiation between the subpopulations was low, our landscape genetic analysis identified both natural (slope) and anthropogenic (roads) landscape variables that have significantly influenced gene flow within this local population. We show that desert tortoise movements at a local scale are influenced by features of the landscape, and that these features are different than those that influence gene flow at larger scales. Our findings are important for desert tortoise conservation and management, particularly in light of recent translocation efforts in the region. More generally, our results indicate that recent landscape changes can affect gene flow at a local scale and that their effects can be detected almost immediately. PMID:22132143

  13. Fine-scale analysis reveals cryptic landscape genetic structure in desert tortoises.

    PubMed

    Latch, Emily K; Boarman, William I; Walde, Andrew; Fleischer, Robert C

    2011-01-01

    Characterizing the effects of landscape features on genetic variation is essential for understanding how landscapes shape patterns of gene flow and spatial genetic structure of populations. Most landscape genetics studies have focused on patterns of gene flow at a regional scale. However, the genetic structure of populations at a local scale may be influenced by a unique suite of landscape variables that have little bearing on connectivity patterns observed at broader spatial scales. We investigated fine-scale spatial patterns of genetic variation and gene flow in relation to features of the landscape in desert tortoise (Gopherus agassizii), using 859 tortoises genotyped at 16 microsatellite loci with associated data on geographic location, sex, elevation, slope, and soil type, and spatial relationship to putative barriers (power lines, roads). We used spatially explicit and non-explicit Bayesian clustering algorithms to partition the sample into discrete clusters, and characterize the relationships between genetic distance and ecological variables to identify factors with the greatest influence on gene flow at a local scale. Desert tortoises exhibit weak genetic structure at a local scale, and we identified two subpopulations across the study area. Although genetic differentiation between the subpopulations was low, our landscape genetic analysis identified both natural (slope) and anthropogenic (roads) landscape variables that have significantly influenced gene flow within this local population. We show that desert tortoise movements at a local scale are influenced by features of the landscape, and that these features are different than those that influence gene flow at larger scales. Our findings are important for desert tortoise conservation and management, particularly in light of recent translocation efforts in the region. More generally, our results indicate that recent landscape changes can affect gene flow at a local scale and that their effects can be detected almost immediately.

  14. Characterizing Intra-Urban Air Quality Gradients with a Spatially-Distributed Network

    NASA Astrophysics Data System (ADS)

    Zimmerman, N.; Ellis, A.; Schurman, M. I.; Gu, P.; Li, H.; Snell, L.; Gu, J.; Subramanian, R.; Robinson, A. L.; Apte, J.; Presto, A. A.

    2016-12-01

    City-wide air pollution measurements have typically relied on regulatory or research monitoring sites with low spatial density to assess population-scale exposure. However, air pollutant concentrations exhibit significant spatial variability depending on local sources and features of the built environment, which may not be well captured by the existing monitoring regime. To better understand urban spatial and temporal pollution gradients at 1 km resolution, a network of 12 real-time air quality monitoring stations was deployed beginning July 2016 in Pittsburgh, PA. The stations were deployed at sites along an urban-rural transect and in urban locations with a range of traffic, restaurant, and tall building densities to examine the impact of various modifiable factors. Measurements from the stationary monitoring stations were further supported by mobile monitoring, which provided higher spatial resolution pollutant measurements on nearby roadways and enabled routine calibration checks. The stationary monitoring measurements comprise ultrafine particle number (Aerosol Dynamics "MAGIC" CPC), PM2.5 (Met One Neighborhood PM Monitor), black carbon (Met One BC 1050), and a new low-cost air quality monitor, the Real-time Affordable Multi-Pollutant (RAMP) sensor package for measuring CO, NO2, SO2, O3, CO2, temperature and relative humidity. High time-resolution (sub-minute) measurements across the distributed monitoring network enable insight into dynamic pollutant behaviour. Our preliminary findings show that our instruments are sensitive to PM2.5 gradients exceeding 2 micro-grams per cubic meter and ultrafine particle gradients exceeding 1000 particles per cubic centimeter. Additionally, we have developed rigorous calibration protocols to characterize the RAMP sensor response and drift, as well as multiple linear regression models to convert sensor response into pollutant concentrations that are comparable to reference instrumentation.

  15. Social isolation induces deficit of latent learning performance in mice: a putative animal model of attention deficit/hyperactivity disorder.

    PubMed

    Ouchi, Hirofumi; Ono, Kazuya; Murakami, Yukihisa; Matsumoto, Kinzo

    2013-02-01

    Social isolation of rodents (SI) elicits a variety of stress responses such as increased aggressiveness, hyper-locomotion, and reduced susceptibility to pentobarbital. To obtain a better understanding of the relevance of SI-induced behavioral abnormalities to psychiatric disorders, we examined the effect of SI on latent learning as an index of spatial attention, and discussed the availability of SI as an epigenetic model of attention deficit hyperactivity disorder (ADHD). Except in specially stated cases, 4-week-old male mice were housed in a group or socially isolated for 3-70 days before experiments. The animals socially isolated for 1 week or more exhibited spatial attention deficit in the water-finding test. Re-socialized rearing for 5 weeks after 1-week SI failed to attenuate the spatial attention deficit. The effect of SI on spatial attention showed no gender difference or correlation with increased aggressive behavior. Moreover, SI had no effect on cognitive performance elucidated in a modified Y-maze or an object recognition test, but it significantly impaired contextual and conditional fear memory elucidated in the fear-conditioning test. Drugs used for ADHD therapy, methylphenidate (1-10 mg/kg, i.p.) and caffeine (0.5-1 mg/kg, i.p.), improved SI-induced latent learning deficit in a manner reversible with cholinergic but not dopaminergic antagonists. Considering the behavioral features of SI mice together with their susceptibility to ADHD drugs, the present findings suggest that SI provides an epigenetic animal model of ADHD and that central cholinergic systems play a role in the effect of methylphenidate on SI-induced spatial attention deficit. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. Inter-rater reliability of kinesthetic measurements with the KINARM robotic exoskeleton.

    PubMed

    Semrau, Jennifer A; Herter, Troy M; Scott, Stephen H; Dukelow, Sean P

    2017-05-22

    Kinesthesia (sense of limb movement) has been extremely difficult to measure objectively, especially in individuals who have survived a stroke. The development of valid and reliable measurements for proprioception is important to developing a better understanding of proprioceptive impairments after stroke and their impact on the ability to perform daily activities. We recently developed a robotic task to evaluate kinesthetic deficits after stroke and found that the majority (~60%) of stroke survivors exhibit significant deficits in kinesthesia within the first 10 days post-stroke. Here we aim to determine the inter-rater reliability of this robotic kinesthetic matching task. Twenty-five neurologically intact control subjects and 15 individuals with first-time stroke were evaluated on a robotic kinesthetic matching task (KIN). Subjects sat in a robotic exoskeleton with their arms supported against gravity. In the KIN task, the robot moved the subjects' stroke-affected arm at a preset speed, direction and distance. As soon as subjects felt the robot begin to move their affected arm, they matched the robot movement with the unaffected arm. Subjects were tested in two sessions on the KIN task: initial session and then a second session (within an average of 18.2 ± 13.8 h of the initial session for stroke subjects), which were supervised by different technicians. The task was performed both with and without the use of vision in both sessions. We evaluated intra-class correlations of spatial and temporal parameters derived from the KIN task to determine the reliability of the robotic task. We evaluated 8 spatial and temporal parameters that quantify kinesthetic behavior. We found that the parameters exhibited moderate to high intra-class correlations between the initial and retest conditions (Range, r-value = [0.53-0.97]). The robotic KIN task exhibited good inter-rater reliability. This validates the KIN task as a reliable, objective method for quantifying kinesthesia after stroke.

  17. Long-Term Species, Sexual and Individual Variations in Foraging Strategies of Fur Seals Revealed by Stable Isotopes in Whiskers

    PubMed Central

    Kernaléguen, Laëtitia; Cazelles, Bernard; Arnould, John P. Y.; Richard, Pierre; Guinet, Christophe; Cherel, Yves

    2012-01-01

    Background Individual variations in the use of the species niche are an important component of diversity in trophic interactions. A challenge in testing consistency of individual foraging strategy is the repeated collection of information on the same individuals. Methodology/Principal Findings The foraging strategies of sympatric fur seals (Arctocephalus gazella and A. tropicalis) were examined using the stable isotope signature of serially sampled whiskers. Most whiskers exhibited synchronous δ13C and δ15N oscillations that correspond to the seal annual movements over the long term (up to 8 years). δ13C and δ15N values were spread over large ranges, with differences between species, sexes and individuals. The main segregating mechanism operates at the spatial scale. Most seals favored foraging in subantarctic waters (where the Crozet Islands are located) where they fed on myctophids. However, A. gazella dispersed in the Antarctic Zone and A. tropicalis more in the subtropics. Gender differences in annual time budget shape the seal movements. Males that do not perform any parental care exhibited large isotopic oscillations reflecting broad annual migrations, while isotopic values of females confined to a limited foraging range during lactation exhibited smaller changes. Limited inter-individual isotopic variations occurred in female seals and in male A. tropicalis. In contrast, male A. gazella showed large inter-individual variations, with some males migrating repeatedly to high-Antarctic waters where they fed on krill, thus meaning that individual specialization occurred over years. Conclusions/Significance Whisker isotopic signature yields unique long-term information on individual behaviour that integrates the spatial, trophic and temporal dimensions of the ecological niche. The method allows depicting the entire realized niche of the species, including some of its less well-known components such as age-, sex-, individual- and migration-related changes. It highlights intrapopulation heterogeneity in foraging strategies that could have important implications for likely demographic responses to environmental variability. PMID:22431988

  18. Spawning site selection and contingent behavior in Common Snook, Centropomus undecimalis.

    PubMed

    Lowerre-Barbieri, Susan; Villegas-Ríos, David; Walters, Sarah; Bickford, Joel; Cooper, Wade; Muller, Robert; Trotter, Alexis

    2014-01-01

    Reproductive behavior affects spatial population structure and our ability to manage for sustainability in marine and diadromous fishes. In this study, we used fishery independent capture-based sampling to evaluate where Common Snook occurred in Tampa Bay and if it changed with spawning season, and passive acoustic telemetry to assess fine scale behavior at an inlet spawning site (2007-2009). Snook concentrated in three areas during the spawning season only one of which fell within the expected spawning habitat. Although in lower numbers, they remained in these areas throughout the winter months. Acoustically-tagged snook (n = 31) showed two seasonal patterns at the spawning site: Most fish occurred during the spawning season but several fish displayed more extended residency, supporting the capture-based findings that Common Snook exhibit facultative catadromy. Spawning site selection for iteroparous, multiple-batch spawning fishes occurs at the lifetime, annual, or intra-annual temporal scales. In this study we show colonization of a new spawning site, indicating that lifetime spawning site fidelity of Common Snook is not fixed at this fine spatial scale. However, individuals did exhibit annual and intra-seasonal spawning site fidelity to this new site over the three years studied. The number of fish at the spawning site increased in June and July (peak spawning months) and on new and full lunar phases indicating within population variability in spawning and movement patterns. Intra-seasonal patterns of detection also differed significantly with sex. Common Snook exhibited divergent migration tactics and habitat use at the annual and estuarine scales, with contingents using different overwintering habitat. Migration tactics also varied at the spawning site at the intra-seasonal scale and with sex. These results have important implications for understanding how reproductive behavior affects spatio-temporal patterns of fish abundance and their resilience to disturbance events and fishing pressure.

  19. Spatial variation in the climatic predictors of species compositional turnover and endemism

    PubMed Central

    Di Virgilio, Giovanni; Laffan, Shawn W; Ebach, Malte C; Chapple, David G

    2014-01-01

    Previous research focusing on broad-scale or geographically invariant species-environment dependencies suggest that temperature-related variables explain more of the variation in reptile distributions than precipitation. However, species–environment relationships may exhibit considerable spatial variation contingent upon the geographic nuances that vary between locations. Broad-scale, geographically invariant analyses may mask this local variation and their findings may not generalize to different locations at local scales. We assess how reptile–climatic relationships change with varying spatial scale, location, and direction. Since the spatial distributions of diversity and endemism hotspots differ for other species groups, we also assess whether reptile species turnover and endemism hotspots are influenced differently by climatic predictors. Using New Zealand reptiles as an example, the variation in species turnover, endemism and turnover in climatic variables was measured using directional moving window analyses, rotated through 360°. Correlations between the species turnover, endemism and climatic turnover results generated by each rotation of the moving window were analysed using multivariate generalized linear models applied at national, regional, and local scales. At national-scale, temperature turnover consistently exhibited the greatest influence on species turnover and endemism, but model predictive capacity was low (typically r2 = 0.05, P < 0.001). At regional scales the relative influence of temperature and precipitation turnover varied between regions, although model predictive capacity was also generally low. Climatic turnover was considerably more predictive of species turnover and endemism at local scales (e.g., r2 = 0.65, P < 0.001). While temperature turnover had the greatest effect in one locale (the northern North Island), there was substantial variation in the relative influence of temperature and precipitation predictors in the remaining four locales. Species turnover and endemism hotspots often occurred in different locations. Climatic predictors had a smaller influence on endemism. Our results caution against assuming that variability in temperature will always be most predictive of reptile biodiversity across different spatial scales, locations and directions. The influence of climatic turnover on the species turnover and endemism of other taxa may exhibit similar patterns of spatial variation. Such intricate variation might be discerned more readily if studies at broad scales are complemented by geographically variant, local-scale analyses. PMID:25473479

  20. Infrared responsivity of a pyroelectric detector with a single-wall carbon nanotube coating.

    PubMed

    Theocharous, E; Engtrakul, C; Dillon, A C; Lehman, J

    2008-08-01

    The performance of a 10 mm diameter pyroelectric detector coated with a single-wall carbon nanotube (SWCNT) was evaluated in the 0.8 to 20 microm wavelength range. The relative spectral responsivity of this detector exhibits significant fluctuations over the wavelength range examined. This is consistent with independent absorbance measurements, which show that SWCNTs exhibit selective absorption bands in the visible and near-infrared. The performance of the detector in terms of noise equivalent power and detectivity in wavelength regions of high coating absorptivity was comparable with gold-black-coated pyroelectric detectors based on 50 microm thick LiTaO(3) crystals. The response of this detector was shown to be nonlinear for DC equivalent photocurrents >10(-9) A, and its spatial uniformity of response was comparable with other pyroelectric detectors utilizing gold-black coatings. The nonuniform spectral responsivity exhibited by the SWCNT-coated detector is expected to severely restrict the use of SWCNTs as black coatings for thermal detectors. However, the deposition of SWCNT coatings on a pyroelectric crystal followed by the study of the prominence of the spectral features in the relative spectral responsivity of the resultant pyroelectric detectors is shown to provide an effective method for quantifying the impurity content in SWCNT samples.

  1. Dependence of long-term persistence properties of precipitation on spatial and regional characteristics

    NASA Astrophysics Data System (ADS)

    Tyralis, Hristos; Dimitriadis, Panayiotis; Iliopoulou, Theano; Tzouka, Katerina; Koutsoyiannis, Demetris

    2017-04-01

    The long-term persistence (LTP), else known in hydrological science as the Hurst phenomenon, is a behaviour observed in geophysical processes in which wet years or dry years are clustered to respective long time periods. A common practice for evaluating the presence of the LTP is to model the geophysical time series with the Hurst-Kolmogorov process (HKp) and estimate its Hurst parameter H where high values of H indicate strong LTP. We estimate H of the mean annual precipitation using instrumental data from approximately 1 500 stations which cover a big area of the earth's surface and span from 1916 to 2015. We regress the H estimates of all stations on their spatial and regional characteristics (i.e. their location, elevation and Köppen-Geiger climate class) using a random forest algorithm. Furthermore, we apply the Mann-Kendall test under the LTP assumption (MKt-LTP) to all time series to assess the significance of observed trends of the mean annual precipitation. To summarize the results, the LTP seems to depend mostly on the location of the stations, while the predictive value of the fitted regression model is good. Thus when investigating for LTP properties we recommend that the local characteristics should be considered. Additionally, the application of the MKt-LTP suggests that no significant monotonic trend can characterize the global precipitation. Dominant positive significant trends are observed mostly in main climate type D (snow), while in the other climate types the percentage of stations with positive significant trends was approximately equal to that of negative significant trends. Furthermore, 50% of all stations do not exhibit significant trends at all.

  2. Spatial Distribution of Phase Singularities in Optical Random Vector Waves.

    PubMed

    De Angelis, L; Alpeggiani, F; Di Falco, A; Kuipers, L

    2016-08-26

    Phase singularities are dislocations widely studied in optical fields as well as in other areas of physics. With experiment and theory we show that the vectorial nature of light affects the spatial distribution of phase singularities in random light fields. While in scalar random waves phase singularities exhibit spatial distributions reminiscent of particles in isotropic liquids, in vector fields their distribution for the different vector components becomes anisotropic due to the direct relation between propagation and field direction. By incorporating this relation in the theory for scalar fields by Berry and Dennis [Proc. R. Soc. A 456, 2059 (2000)], we quantitatively describe our experiments.

  3. Spatial connections in regional climate model rainfall outputs at different temporal scales: Application of network theory

    NASA Astrophysics Data System (ADS)

    Naufan, Ihsan; Sivakumar, Bellie; Woldemeskel, Fitsum M.; Raghavan, Srivatsan V.; Vu, Minh Tue; Liong, Shie-Yui

    2018-01-01

    Understanding the spatial and temporal variability of rainfall has always been a great challenge, and the impacts of climate change further complicate this issue. The present study employs the concepts of complex networks to study the spatial connections in rainfall, with emphasis on climate change and rainfall scaling. Rainfall outputs (during 1961-1990) from a regional climate model (i.e. Weather Research and Forecasting (WRF) model that downscaled the European Centre for Medium-range Weather Forecasts, ECMWF ERA-40 reanalyses) over Southeast Asia are studied, and data corresponding to eight different temporal scales (6-hr, 12-hr, daily, 2-day, 4-day, weekly, biweekly, and monthly) are analyzed. Two network-based methods are applied to examine the connections in rainfall: clustering coefficient (a measure of the network's local density) and degree distribution (a measure of the network's spread). The influence of rainfall correlation threshold (T) on spatial connections is also investigated by considering seven different threshold levels (ranging from 0.5 to 0.8). The results indicate that: (1) rainfall networks corresponding to much coarser temporal scales exhibit properties similar to that of small-world networks, regardless of the threshold; (2) rainfall networks corresponding to much finer temporal scales may be classified as either small-world networks or scale-free networks, depending upon the threshold; and (3) rainfall spatial connections exhibit a transition phase at intermediate temporal scales, especially at high thresholds. These results suggest that the most appropriate model for studying spatial connections may often be different at different temporal scales, and that a combination of small-world and scale-free network models might be more appropriate for rainfall upscaling/downscaling across all scales, in the strict sense of scale-invariance. The results also suggest that spatial connections in the studied rainfall networks in Southeast Asia are weak, especially when more stringent conditions are imposed (i.e. when T is very high), except at the monthly scale.

  4. A composite likelihood approach for spatially correlated survival data

    PubMed Central

    Paik, Jane; Ying, Zhiliang

    2013-01-01

    The aim of this paper is to provide a composite likelihood approach to handle spatially correlated survival data using pairwise joint distributions. With e-commerce data, a recent question of interest in marketing research has been to describe spatially clustered purchasing behavior and to assess whether geographic distance is the appropriate metric to describe purchasing dependence. We present a model for the dependence structure of time-to-event data subject to spatial dependence to characterize purchasing behavior from the motivating example from e-commerce data. We assume the Farlie-Gumbel-Morgenstern (FGM) distribution and then model the dependence parameter as a function of geographic and demographic pairwise distances. For estimation of the dependence parameters, we present pairwise composite likelihood equations. We prove that the resulting estimators exhibit key properties of consistency and asymptotic normality under certain regularity conditions in the increasing-domain framework of spatial asymptotic theory. PMID:24223450

  5. Are Deaf Students Visual Learners?

    PubMed Central

    Marschark, Marc; Morrison, Carolyn; Lukomski, Jennifer; Borgna, Georgianna; Convertino, Carol

    2013-01-01

    It is frequently assumed that by virtue of their hearing losses, deaf students are visual learners. Deaf individuals have some visual-spatial advantages relative to hearing individuals, but most have been are linked to use of sign language rather than auditory deprivation. How such cognitive differences might affect academic performance has been investigated only rarely. This study examined relations among deaf college students’ language and visual-spatial abilities, mathematics problem solving, and hearing thresholds. Results extended some previous findings and clarified others. Contrary to what might be expected, hearing students exhibited visual-spatial skills equal to or better than deaf students. Scores on a Spatial Relations task were associated with better mathematics problem solving. Relations among the several variables, however, suggested that deaf students are no more likely to be visual learners than hearing students and that their visual-spatial skill may be related more to their hearing than to sign language skills. PMID:23750095

  6. A composite likelihood approach for spatially correlated survival data.

    PubMed

    Paik, Jane; Ying, Zhiliang

    2013-01-01

    The aim of this paper is to provide a composite likelihood approach to handle spatially correlated survival data using pairwise joint distributions. With e-commerce data, a recent question of interest in marketing research has been to describe spatially clustered purchasing behavior and to assess whether geographic distance is the appropriate metric to describe purchasing dependence. We present a model for the dependence structure of time-to-event data subject to spatial dependence to characterize purchasing behavior from the motivating example from e-commerce data. We assume the Farlie-Gumbel-Morgenstern (FGM) distribution and then model the dependence parameter as a function of geographic and demographic pairwise distances. For estimation of the dependence parameters, we present pairwise composite likelihood equations. We prove that the resulting estimators exhibit key properties of consistency and asymptotic normality under certain regularity conditions in the increasing-domain framework of spatial asymptotic theory.

  7. Temporal scaling and spatial statistical analyses of groundwater level fluctuations

    NASA Astrophysics Data System (ADS)

    Sun, H.; Yuan, L., Sr.; Zhang, Y.

    2017-12-01

    Natural dynamics such as groundwater level fluctuations can exhibit multifractionality and/or multifractality due likely to multi-scale aquifer heterogeneity and controlling factors, whose statistics requires efficient quantification methods. This study explores multifractionality and non-Gaussian properties in groundwater dynamics expressed by time series of daily level fluctuation at three wells located in the lower Mississippi valley, after removing the seasonal cycle in the temporal scaling and spatial statistical analysis. First, using the time-scale multifractional analysis, a systematic statistical method is developed to analyze groundwater level fluctuations quantified by the time-scale local Hurst exponent (TS-LHE). Results show that the TS-LHE does not remain constant, implying the fractal-scaling behavior changing with time and location. Hence, we can distinguish the potentially location-dependent scaling feature, which may characterize the hydrology dynamic system. Second, spatial statistical analysis shows that the increment of groundwater level fluctuations exhibits a heavy tailed, non-Gaussian distribution, which can be better quantified by a Lévy stable distribution. Monte Carlo simulations of the fluctuation process also show that the linear fractional stable motion model can well depict the transient dynamics (i.e., fractal non-Gaussian property) of groundwater level, while fractional Brownian motion is inadequate to describe natural processes with anomalous dynamics. Analysis of temporal scaling and spatial statistics therefore may provide useful information and quantification to understand further the nature of complex dynamics in hydrology.

  8. A statistical evaluation of non-ergodic variogram estimators

    USGS Publications Warehouse

    Curriero, F.C.; Hohn, M.E.; Liebhold, A.M.; Lele, S.R.

    2002-01-01

    Geostatistics is a set of statistical techniques that is increasingly used to characterize spatial dependence in spatially referenced ecological data. A common feature of geostatistics is predicting values at unsampled locations from nearby samples using the kriging algorithm. Modeling spatial dependence in sampled data is necessary before kriging and is usually accomplished with the variogram and its traditional estimator. Other types of estimators, known as non-ergodic estimators, have been used in ecological applications. Non-ergodic estimators were originally suggested as a method of choice when sampled data are preferentially located and exhibit a skewed frequency distribution. Preferentially located samples can occur, for example, when areas with high values are sampled more intensely than other areas. In earlier studies the visual appearance of variograms from traditional and non-ergodic estimators were compared. Here we evaluate the estimators' relative performance in prediction. We also show algebraically that a non-ergodic version of the variogram is equivalent to the traditional variogram estimator. Simulations, designed to investigate the effects of data skewness and preferential sampling on variogram estimation and kriging, showed the traditional variogram estimator outperforms the non-ergodic estimators under these conditions. We also analyzed data on carabid beetle abundance, which exhibited large-scale spatial variability (trend) and a skewed frequency distribution. Detrending data followed by robust estimation of the residual variogram is demonstrated to be a successful alternative to the non-ergodic approach.

  9. Wisconsin's approach to variation in traffic data

    DOT National Transportation Integrated Search

    2000-08-01

    Traffic data exhibits considerable variability, both spatially and temporally. Given limited resources and the large geographic coverage required for data collection efforts, short period (24-hours to 7-day) traffic data collection must often serve t...

  10. Inter-individual Differences in Exercise-Induced Spatial Working Memory Improvement: A Near-Infrared Spectroscopy Study.

    PubMed

    Yamazaki, Yudai; Sato, Daisuke; Yamashiro, Koya; Tsubaki, Atsuhiro; Yamaguchi, Yui; Takehara, Nana; Maruyama, Atsuo

    2017-01-01

    Acute aerobic exercise at a mild intensity improves cognitive function. However, the response to exercise exhibits inter-individual differences, and the mechanisms underlying these differences remain unclear. The objective of this study was to determine potential factors in the brain that underlie differential responses to exercise in terms of cognitive improvement using functional near-infrared spectroscopy. Fourteen healthy subjects participated in these experiments. Participants performed a low intensity cycling exercise at 30% maximal oxygen uptake (VO 2peak ) for 10 min and performed a spatial memory task before and after exercising (5 and 30 min). The spatial memory task comprised two levels of difficulty (low: 1-dot EXERCISE, high: 3-dot EXERCISE). Cortical oxy-hemoglobin (O 2 Hb) levels were recorded using near-infrared spectroscopy during both the exercise and the spatial memory task phases. Regions of interests included the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), and frontopolar area (FPA). The participants were divided into two groups depending on whether they were responders (improved task reaction time) or non-responders (no improvement). Subsequently, we analyzed the group characteristics and differences in the change in O 2 Hb levels during exercise and spatial working memory tasks. Acute mild exercise significantly improved mean reaction times in the 1-dot memory task but not in the 3-dot task across the participants. In the 1-dot EXERCISE, 10 subjects were responders and four subjects were non-responders, whereas in the 3-dot EXERCISE, seven subjects were non-responders. In responders, during exercise, we found higher O 2 Hb levels in the right VLPFC response for the 1-dot memory task. Acute mild exercise caused inter-individual differences in spatial memory improvement, which were associated with changes in O 2 Hb activity in the prefrontal area during the exercise phase but not during the actual spatial memory task. Therefore, individuals who respond with higher reactivity to mild intensity exercise in the VLPFC might obtain larger spatial working memory improvements following exercise than non-responders.

  11. Risk assessment of groundwater level variability using variable Kriging methods

    NASA Astrophysics Data System (ADS)

    Spanoudaki, Katerina; Kampanis, Nikolaos A.

    2015-04-01

    Assessment of the water table level spatial variability in aquifers provides useful information regarding optimal groundwater management. This information becomes more important in basins where the water table level has fallen significantly. The spatial variability of the water table level in this work is estimated based on hydraulic head measured during the wet period of the hydrological year 2007-2008, in a sparsely monitored basin in Crete, Greece, which is of high socioeconomic and agricultural interest. Three Kriging-based methodologies are elaborated in Matlab environment to estimate the spatial variability of the water table level in the basin. The first methodology is based on the Ordinary Kriging approach, the second involves auxiliary information from a Digital Elevation Model in terms of Residual Kriging and the third methodology calculates the probability of the groundwater level to fall below a predefined minimum value that could cause significant problems in groundwater resources availability, by means of Indicator Kriging. The Box-Cox methodology is applied to normalize both the data and the residuals for improved prediction results. In addition, various classical variogram models are applied to determine the spatial dependence of the measurements. The Matérn model proves to be the optimal, which in combination with Kriging methodologies provides the most accurate cross validation estimations. Groundwater level and probability maps are constructed to examine the spatial variability of the groundwater level in the basin and the associated risk that certain locations exhibit regarding a predefined minimum value that has been set for the sustainability of the basin's groundwater resources. Acknowledgement The work presented in this paper has been funded by the Greek State Scholarships Foundation (IKY), Fellowships of Excellence for Postdoctoral Studies (Siemens Program), 'A simulation-optimization model for assessing the best practices for the protection of surface water and groundwater in the coastal zone', (2013 - 2015). Varouchakis, E. A. and D. T. Hristopulos (2013). "Improvement of groundwater level prediction in sparsely gauged basins using physical laws and local geographic features as auxiliary variables." Advances in Water Resources 52: 34-49. Kitanidis, P. K. (1997). Introduction to geostatistics, Cambridge: University Press.

  12. An Evaluation of Spatial Organization of the Church Architecture of Kerala during the Sixteenth to Seventeenth Centuries

    NASA Astrophysics Data System (ADS)

    Panjikaran, S.; Vedamuthu, R.

    2013-05-01

    The churches of Kerala of the sixteenth to seventeenth centuries exhibits an architectural character which is different from that of the indigenous Church Architecture of Kerala. Preliminary studies show that the spatial organization of these churches also varied from that of the indigenous churches of Kerala. Did these variations in spatial organization arise of any change in functional requirements of churches? How did the indigenous Architectural character adapt to these changes or did it give way to a new style? The objective of this study is to understand the spatial organization of the indigenous Church Architecture of Kerala and to evaluate the changes in spatial organization during the sixteenth to seventeenth centuries. This study is primarily based on field survey and documentation, evaluation is done by relying on the Rapoport's theory. It is concluded that the church architecture of this period is a fusion of the Western and Eastern ecclesiastical traditions in terms of spatial organization and planning.

  13. Spatial Inference for Distributed Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Braverman, A. J.; Katzfuss, M.; Nguyen, H.

    2014-12-01

    Remote sensing data are inherently spatial, and a substantial portion of their value for scientific analyses derives from the information they can provide about spatially dependent processes. Geophysical variables such as atmopsheric temperature, cloud properties, humidity, aerosols and carbon dioxide all exhibit spatial patterns, and satellite observations can help us learn about the physical mechanisms driving them. However, remote sensing observations are often noisy and incomplete, so inferring properties of true geophysical fields from them requires some care. These data can also be massive, which is both a blessing and a curse: using more data drives uncertainties down, but also drives costs up, particularly when data are stored on different computers or in different physical locations. In this talk I will discuss a methodology for spatial inference on massive, distributed data sets that does not require moving large volumes of data. The idea is based on a combination of ideas including modeling spatial covariance structures with low-rank covariance matrices, and distributed estimation in sensor or wireless networks.

  14. Within-field spatial distribution of Megacopta cribraria (Hemiptera: Plataspidae) in soybean (Fabales: Fabaceae).

    PubMed

    Seiter, Nicholas J; Reay-Jones, Francis P F; Greene, Jeremy K

    2013-12-01

    The recently introduced plataspid Megacopta cribraria (F.) can infest fields of soybean (Glycine max (L.) Merrill) in the southeastern United States. Grid sampling in four soybean fields was conducted in 2011 and 2012 to study the spatial distribution of M. cribraria adults, nymphs, and egg masses. Peak oviposition typically occurred in early August, while peak levels of adults occurred in mid-late September. The overall sex ratio was slightly biased at 53.1 ± 0.2% (SEM) male. Sweep samples of nymphs were biased toward late instars. All three life stages exhibited a generally aggregated spatial distribution based on Taylor's power law, Iwao's patchiness regression, and spatial analysis by distance indices (SADIE). Interpolation maps of local SADIE aggregation indices showed clusters of adults and nymphs located at field edges, and mean densities of adults were higher in samples taken from field edges than in those taken from field interiors. Adults and nymphs were often spatially associated based on SADIE, indicating spatial stability across life stages.

  15. Sports training enhances visuo-spatial cognition regardless of open-closed typology

    PubMed Central

    Hsieh, Shu-Shih; Chen, Kuan-Fu; Chang, Yu-Kai

    2017-01-01

    The aim of this study was to investigate the effects of open and closed sport participation on visuo-spatial attention and memory performance among young adults. Forty-eight young adults—16 open-skill athletes, 16 closed-skill athletes, and 16 non-athletes controls—were recruited for the study. Both behavioral performance and event-related potential (ERP) measurement were assessed when participants performed non-delayed and delayed match-to-sample task that tested visuo-spatial attention and memory processing. Results demonstrated that regardless of training typology, the athlete groups exhibited shorter reaction times in both the visuo-spatial attention and memory conditions than the control group with no existence of speed-accuracy trade-off. Similarly, a larger P3 amplitudes were observed in both athlete groups than in the control group for the visuo-spatial memory condition. These findings suggest that sports training, regardless of typology, are associated with superior visuo-spatial attention and memory performance, and more efficient neural resource allocation in memory processing. PMID:28560098

  16. Regional sea level projections with observed gauge, altimeter and reconstructed data along China coast

    NASA Astrophysics Data System (ADS)

    Du, L.; Shi, H.; Zhang, S.

    2017-12-01

    Acting as the typical shelf seas in northwest Pacific Ocean, regional sea level along China coasts exhibits complicated and multiscale spatial-temporal characteristics under circumstance of global change. In this paper, sea level variability is investigated with tide gauges records, satellite altimetry data, reconstructed sea surface height, and CMIP simulation fields. Sea level exhibits the interannual variability imposing on a remarkable sea level rising in the China seas and coastal region, although its seasonal signals are significant as the results of global ocean. Sea level exhibits faster rising rate during the satellite altimetry era, nearly twice to the rate during the last sixty years. AVISO data and reconstructed sea surface heights illustrate good correlation coefficient, more than 0.8. Interannual sea level variation is mainly modulated by the low-frequency variability of wind fields over northern Pacific Ocean by local and remote processes. Meanwhile sea level varies obviously by the transport fluctuation and bimodality path of Kuroshio. Its variability possibly linked to internal variability of the ocean-atmosphere system influenced by ENSO oscillation. China Sea level have been rising during the 20th century, and are projected to continue to rise during this century. Sea level can reach the highest extreme level in latter half of 21st century. Modeled sea level including regional sea level projection combined with the IPCC climate scenarios play a significant role on coastal storm surge evolution. The vulnerable regions along the ECS coast will suffer from the increasing storm damage with sea level variations.

  17. On extreme events for non-spatial and spatial branching Brownian motions

    NASA Astrophysics Data System (ADS)

    Avan, Jean; Grosjean, Nicolas; Huillet, Thierry

    2015-04-01

    We study the impact of having a non-spatial branching mechanism with infinite variance on some parameters (height, width and first hitting time) of an underlying Bienaymé-Galton-Watson branching process. Aiming at providing a comparative study of the spread of an epidemics whose dynamics is given by the modulus of a branching Brownian motion (BBM) we then consider spatial branching processes in dimension d, not necessarily integer. The underlying branching mechanism is either a binary branching model or one presenting infinite variance. In particular we evaluate the chance p(x) of being hit if the epidemics started away at distance x. We compute the large x tail probabilities of this event, both when the branching mechanism is regular and when it exhibits very large fluctuations.

  18. Choroid plexus implants rescue Alzheimer's disease-like pathologies by modulating amyloid-β degradation.

    PubMed

    Bolos, Marta; Antequera, Desireé; Aldudo, Jesús; Kristen, Henrike; Bullido, María Jesús; Carro, Eva

    2014-08-01

    The choroid plexuses (CP) release numerous biologically active enzymes and neurotrophic factors, and contain a subpopulation of neural progenitor cells providing the capacity to proliferate and differentiate into other types of cells. These characteristics make CP epithelial cells (CPECs) excellent candidates for cell therapy aiming at restoring brain tissue in neurodegenerative illnesses, including Alzheimer's disease (AD). In the present study, using in vitro approaches, we demonstrated that CP were able to diminish amyloid-β (Aβ) levels in cell cultures, reducing Aβ-induced neurotoxicity. For in vivo studies, CPECs were transplanted into the brain of the APP/PS1 murine model of AD that exhibits advanced Aβ accumulation and memory impairment. Brain examination after cell implantation revealed a significant reduction in brain Aβ deposits, hyperphosphorylation of tau, and astrocytic reactivity. Remarkably, the transplantation of CPECs was accompanied by a total behavioral recovery in APP/PS1 mice, improving spatial and non-spatial memory. These findings reinforce the neuroprotective potential of CPECs and the use of cell therapies as useful tools in AD.

  19. Spatial and temporal variation of freely dissolved PAHs in an urban river undergoing Superfund remediation

    PubMed Central

    Sower, GJ; Anderson, K.A.

    2014-01-01

    Urban rivers with a history of industrial use can exhibit spatial and temporal variations in contaminant concentrations that may significantly affect risk evaluations and even the assessment of remediation efforts. Concentrations of 15 biologically available priority pollutant polycyclic aromatic hydrocarbons (PAHs) were measured over five years along 18.5 miles of the lower Willamette River using passive sampling devices and HPLC. The study area includes the Portland Harbor Superfund megasite with several PAH sources including remediation operations for coal tar at RM 6.3 west and an additional Superfund site, McCormick and Baxter, at RM 7 east consisting largely of creosote contamination. Study results show that organoclay capping at the McCormick and Baxter Superfund Site reduced PAHs from a pre-cap average of 440 ± 422 ng/L to 8 ± 3 ng/L post-capping. Results also reveal that dredging of submerged coal tar nearly tripled nearby freely dissolved PAH concentrations. For apportioning sources, fluoranthene/ pyrene and phenanthrene/anthracene diagnostic ratios from passive sampling devices were established for creosote and coal tar contamination and compared to published sediment values. PMID:19174872

  20. Spatial and temporal variation of freely dissolved polycyclic aromatic hydrocarbons in an urban river undergoing Superfund remediation.

    PubMed

    Sower, Gregory James; Anderson, Kim A

    2008-12-15

    Urban rivers with a history of industrial use can exhibit spatial and temporal variations in contaminant concentrations that may significantly affect risk evaluations and even the assessment of remediation efforts. Concentrations of 15 biologically available priority pollutant polycyclic aromatic hydrocarbons (PAHs) were measured over five years along 18.5 miles of the lower Willamette River using passive sampling devices and HPLC. The study area includes the Portland Harbor Superfund megasite with several PAH sources including remediation operations for coal tar at RM 6.3 west and an additional Superfund site, McCormick and Baxter, at RM 7 east consisting largely of creosote contamination. Study results show that organoclay capping at the McCormick and Baxter Superfund Site reduced PAHs from a precap average of 440 +/- 422 ng/L to 8 +/- 3 ng/L postcapping. Results also reveal that dredging of submerged coal tar nearly tripled nearby freely dissolved PAH concentrations. For apportioning sources, fluoranthene/pyrene and phenanthrene/anthracene diagnostic ratios from passive sampling devices were established for creosote and coal tar contamination and compared to published sediment values.

  1. Modified symplectic schemes with nearly-analytic discrete operators for acoustic wave simulations

    NASA Astrophysics Data System (ADS)

    Liu, Shaolin; Yang, Dinghui; Lang, Chao; Wang, Wenshuai; Pan, Zhide

    2017-04-01

    Using a structure-preserving algorithm significantly increases the computational efficiency of solving wave equations. However, only a few explicit symplectic schemes are available in the literature, and the capabilities of these symplectic schemes have not been sufficiently exploited. Here, we propose a modified strategy to construct explicit symplectic schemes for time advance. The acoustic wave equation is transformed into a Hamiltonian system. The classical symplectic partitioned Runge-Kutta (PRK) method is used for the temporal discretization. Additional spatial differential terms are added to the PRK schemes to form the modified symplectic methods and then two modified time-advancing symplectic methods with all of positive symplectic coefficients are then constructed. The spatial differential operators are approximated by nearly-analytic discrete (NAD) operators, and we call the fully discretized scheme modified symplectic nearly analytic discrete (MSNAD) method. Theoretical analyses show that the MSNAD methods exhibit less numerical dispersion and higher stability limits than conventional methods. Three numerical experiments are conducted to verify the advantages of the MSNAD methods, such as their numerical accuracy, computational cost, stability, and long-term calculation capability.

  2. Image-receptor performance: a comparison of Trophy RVG UI sensor and Kodak Ektaspeed Plus film.

    PubMed

    Ludlow, J; Mol, A

    2001-01-01

    Objective. This study compares the physical characteristics of the RVG UI sensor (RVG) with Ektaspeed Plus film. Dose-response curves were generated for film and for each of 6 available RVG modes. An aluminum step-wedge was used to evaluate exposure latitude. Spatial resolution was assessed by using a line-pair test tool. Latitude and resolution were assessed by observers for both modalities. The RVG was further characterized by its modulation transfer function. Exposure latitude was equal for film and RVG in the periodontal mode. Other gray scale modes demonstrated much lower latitude. The average maximum resolution was 15.3 line-pairs per millimeter (lp/mm) for RVG in high-resolution mode, 10.5 lp/mm for RVG in low-resolution mode, and 20 lp/mm for film (P <.0001). Modulation transfer function measurements supported the subjective assessments. In periodontal mode, the RVG UI sensor demonstrates exposure latitude similar to that of Ektaspeed Plus film. Film images exhibit significantly higher spatial resolution than the RVG images acquired in high-resolution mode.

  3. Role of activity-dependent BDNF expression in hippocampal–prefrontal cortical regulation of behavioral perseverance

    PubMed Central

    Sakata, Kazuko; Martinowich, Keri; Woo, Newton H.; Schloesser, Robert J.; Jimenez, Dennisse V.; Ji, Yuanyuan; Shen, Liya; Lu, Bai

    2013-01-01

    Activity-dependent gene transcription, including that of the brain-derived neurotrophic factor (Bdnf) gene, has been implicated in various cognitive functions. We previously demonstrated that mutant mice with selective disruption of activity-dependent BDNF expression (BDNF-KIV mice) exhibit deficits in GABA-mediated inhibition in the prefrontal cortex (PFC). Here, we show that disruption of activity-dependent BDNF expression impairs BDNF-dependent late-phase long-term potentiation (L-LTP) in CA1, a site of hippocampal output to the PFC. Interestingly, early-phase LTP and conventional L-LTP induced by strong tetanic stimulation were completely normal in BDNF-KIV mice. In parallel, attenuation of activity-dependent BDNF expression significantly impairs spatial memory reversal and contextual memory extinction, two executive functions that require intact hippocampal–PFC circuitry. In contrast, spatial and contextual memory per se were not affected. Thus, activity-dependent BDNF expression in the hippocampus and PFC may contribute to cognitive and behavioral flexibility. These results suggest distinct roles for different forms of L-LTP and provide a link between activity-dependent BDNF expression and behavioral perseverance, a hallmark of several psychiatric disorders. PMID:23980178

  4. Experimental Evaluation of Depth-of-Interaction Correction in a Small-Animal Positron Emission Tomography Scanner

    PubMed Central

    Green, Michael V.; Ostrow, Harold G.; Seidel, Jurgen; Pomper, Martin G.

    2013-01-01

    Human and small-animal positron emission tomography (PET) scanners with cylindrical geometry and conventional detectors exhibit a progressive reduction in radial spatial resolution with increasing radial distance from the geometric axis of the scanner. This “depth-of-interaction” (DOI) effect is sufficiently deleterious that many laboratories have devised novel schemes to reduce the magnitude of this effect and thereby yield PET images of greater quantitative accuracy. Here we examine experimentally the effects of a particular DOI correction method (dual-scintillator phoswich detectors with pulse shape discrimination) implemented in a small-animal PET scanner by comparing the same phantom and same mouse images with and without DOI correction. The results suggest that even this relatively coarse, two-level estimate of radial gamma ray interaction position significantly reduces the DOI parallax error. This study also confirms two less appreciated advantages of DOI correction: a reduction in radial distortion and radial source displacement as a source is moved toward the edge of the field of view and a resolution improvement detectable in the central field of view likely owing to improved spatial sampling. PMID:21084028

  5. Experimental evaluation of depth-of-interaction correction in a small-animal positron emission tomography scanner.

    PubMed

    Green, Michael V; Ostrow, Harold G; Seidel, Jurgen; Pomper, Martin G

    2010-12-01

    Human and small-animal positron emission tomography (PET) scanners with cylindrical geometry and conventional detectors exhibit a progressive reduction in radial spatial resolution with increasing radial distance from the geometric axis of the scanner. This "depth-of-interaction" (DOI) effect is sufficiently deleterious that many laboratories have devised novel schemes to reduce the magnitude of this effect and thereby yield PET images of greater quantitative accuracy. Here we examine experimentally the effects of a particular DOI correction method (dual-scintillator phoswich detectors with pulse shape discrimination) implemented in a small-animal PET scanner by comparing the same phantom and same mouse images with and without DOI correction. The results suggest that even this relatively coarse, two-level estimate of radial gamma ray interaction position significantly reduces the DOI parallax error. This study also confirms two less appreciated advantages of DOI correction: a reduction in radial distortion and radial source displacement as a source is moved toward the edge of the field of view and a resolution improvement detectable in the central field of view likely owing to improved spatial sampling.

  6. Baseline element concentrations in soils and plants, Wattenmeer National Park, North and East Frisian Islands, Federal Republic of Germany

    USGS Publications Warehouse

    Severson, R.C.; Gough, L.P.; van den Boom, G.

    1992-01-01

    Baseline element concentrations are given for dune grass (Ammophilia arenaria), willow (Salix repens), moss (Hylocomium splendens) and associated surface soils. Baseline and variability data for pH, ash, Al, As, Ba, C, Ca, Cd, Ce, Co, Cr, Cu, Fe, Hg, K, La, Li, Mg, Mn, Na, Nb, Nd, Ni, P, Pb, S, Sc, Se, Sr, Th, Ti, V, Y, Yb, and Zn are reported; however, not all variables are reported for all media because, in some media, certain elements were below the analytical detection limit. Spatial variation in element concentration between five Frisian Islands are given for each of the sample media. In general, only a few elements in each media showed statistically significant differences between the islands sampled. The measured concentrations in all sample media exhibited ranges that cannot be attributed to anthropogenic additions of trace elements, with the possible exception of Hg and Pb in surface soils.Baseline element concentrations are given for dune grass (Ammophilia arenaria), willow (Salix repens), moss (Hylocomium splendens) and associated surface soils. Baseline and variability data for pH, ash, Al, As, Ba, C, Ca, Cd, Ce, Co, Cr, Cu, Fe, Hg, K, La, Li, Mg, Mn, Na, Nb, Nd, Ni, P, Pb, S, Sc, Se, Sr, Th, Ti, V, Y, Yb, and Zn are reported; however, not all variables are reported for all media because, in some media, certain elements were below the analytical detection limit. Spatial variation in element concentration between five Frisian Islands are given for each of the sample media. In general, only a few elements in each media showed statistically significant differences between the islands sampled. The measured concentrations in all sample media exhibited ranges that cannot be attributed to anthropogenic additions of trace elements, with the possible exception of Hg and Pb in surface soils.

  7. Modeling uncertainty and correlation in soil properties using Restricted Pairing and implications for ensemble-based hillslope-scale soil moisture and temperature estimation

    NASA Astrophysics Data System (ADS)

    Flores, A. N.; Entekhabi, D.; Bras, R. L.

    2007-12-01

    Soil hydraulic and thermal properties (SHTPs) affect both the rate of moisture redistribution in the soil column and the volumetric soil water capacity. Adequately constraining these properties through field and lab analysis to parameterize spatially-distributed hydrology models is often prohibitively expensive. Because SHTPs vary significantly at small spatial scales individual soil samples are also only reliably indicative of local conditions, and these properties remain a significant source of uncertainty in soil moisture and temperature estimation. In ensemble-based soil moisture data assimilation, uncertainty in the model-produced prior estimate due to associated uncertainty in SHTPs must be taken into account to avoid under-dispersive ensembles. To treat SHTP uncertainty for purposes of supplying inputs to a distributed watershed model we use the restricted pairing (RP) algorithm, an extension of Latin Hypercube (LH) sampling. The RP algorithm generates an arbitrary number of SHTP combinations by sampling the appropriate marginal distributions of the individual soil properties using the LH approach, while imposing a target rank correlation among the properties. A previously-published meta- database of 1309 soils representing 12 textural classes is used to fit appropriate marginal distributions to the properties and compute the target rank correlation structure, conditioned on soil texture. Given categorical soil textures, our implementation of the RP algorithm generates an arbitrarily-sized ensemble of realizations of the SHTPs required as input to the TIN-based Realtime Integrated Basin Simulator with vegetation dynamics (tRIBS+VEGGIE) distributed parameter ecohydrology model. Soil moisture ensembles simulated with RP- generated SHTPs exhibit less variance than ensembles simulated with SHTPs generated by a scheme that neglects correlation among properties. Neglecting correlation among SHTPs can lead to physically unrealistic combinations of parameters that exhibit implausible hydrologic behavior when input to the tRIBS+VEGGIE model.

  8. Measuring variability in trophic status in the Lake Waco/Bosque River Watershed

    PubMed Central

    Rodriguez, Angela D; Matlock, Marty D

    2008-01-01

    Background Nutrient management in rivers and streams is difficult due to the spatial and temporal variability of algal growth responses. The objectives of this project were to determine the spatial and seasonal in situ variability of trophic status in the Lake Waco/Bosque River watershed, determine the variability in the lotic ecosystem trophic status index (LETSI) at each site as indicators of the system's nutrient sensitivity, and determine if passive diffusion periphytometers could provide threshold algal responses to nutrient enrichment. Methods We used the passive diffusion periphytometer to measure in-situ nutrient limitation and trophic status at eight sites in five streams in the Lake Waco/Bosque River Watershed in north-central Texas from July 1997 through October 1998. The chlorophyll a production in the periphytometers was used as an indicator of baseline chlorophyll a productivity and of maximum primary productivity (MPP) in response to nutrient enrichment (nitrogen and phosphorus). We evaluated the lotic ecosystem trophic status index (LETSI) using the ratio of baseline primary productivity to MPP, and evaluated the trophic class of each site. Results The rivers and streams in the Lake Waco/Bosque River Watershed exhibited varying degrees of nutrient enrichment over the 18-month sampling period. The North Bosque River at the headwaters (NB-02) located below the Stephenville, Texas wastewater treatment outfall consistently exhibited the highest degree of water quality impact due to nutrient enrichment. Sites at the outlet of the watershed (NB-04 and NB-05) were the next most enriched sites. Trophic class varied for enriched sites over seasons. Conclusion Seasonality played a significant role in the trophic class and sensitivity of each site to nutrients. Managing rivers and streams for nutrients will require methods for measuring in situ responses and sensitivities to nutrient enrichment. Nutrient enrichment periphytometers show significant potential for use in nutrient gradient studies. PMID:18271947

  9. Measuring variability in trophic status in the Lake Waco/Bosque River Watershed.

    PubMed

    Rodriguez, Angela D; Matlock, Marty D

    2008-01-11

    Nutrient management in rivers and streams is difficult due to the spatial and temporal variability of algal growth responses. The objectives of this project were to determine the spatial and seasonal in situ variability of trophic status in the Lake Waco/Bosque River watershed, determine the variability in the lotic ecosystem trophic status index (LETSI) at each site as indicators of the system's nutrient sensitivity, and determine if passive diffusion periphytometers could provide threshold algal responses to nutrient enrichment. We used the passive diffusion periphytometer to measure in-situ nutrient limitation and trophic status at eight sites in five streams in the Lake Waco/Bosque River Watershed in north-central Texas from July 1997 through October 1998. The chlorophyll a production in the periphytometers was used as an indicator of baseline chlorophyll a productivity and of maximum primary productivity (MPP) in response to nutrient enrichment (nitrogen and phosphorus). We evaluated the lotic ecosystem trophic status index (LETSI) using the ratio of baseline primary productivity to MPP, and evaluated the trophic class of each site. The rivers and streams in the Lake Waco/Bosque River Watershed exhibited varying degrees of nutrient enrichment over the 18-month sampling period. The North Bosque River at the headwaters (NB-02) located below the Stephenville, Texas wastewater treatment outfall consistently exhibited the highest degree of water quality impact due to nutrient enrichment. Sites at the outlet of the watershed (NB-04 and NB-05) were the next most enriched sites. Trophic class varied for enriched sites over seasons. Seasonality played a significant role in the trophic class and sensitivity of each site to nutrients. Managing rivers and streams for nutrients will require methods for measuring in situ responses and sensitivities to nutrient enrichment. Nutrient enrichment periphytometers show significant potential for use in nutrient gradient studies.

  10. Natal location influences movement and survival of a spatially structured population of snail kites

    USGS Publications Warehouse

    Martin, J.; Kitchens, W.M.; Hines, J.E.

    2007-01-01

    Despite the accepted importance of the need to better understand how natal location affects movement decisions and survival of animals, robust estimates of movement and survival in relation to the natal location are lacking. Our study focuses on movement and survival related to the natal location of snail kites in Florida and shows that kites, in addition to exhibiting a high level of site tenacity to breeding regions, also exhibit particular attraction to their natal region. More specifically, we found that estimates of movement from post-dispersal regions were greater toward natal regions than toward non-natal regions (differences were significant for three of four regions). We also found that estimates of natal philopatry were greater than estimates of philopatry to non-natal regions (differences were statistically significant for two of four regions). A previous study indicated an effect of natal region on juvenile survival; in this study, we show an effect of natal region on adult survival. Estimates of adult survival varied among kites that were hatched in different regions. Adults experienced mortality rates characteristic of the region occupied at the time when survival was measured, but because there is a greater probability that kites will return to their natal region than to any other regions, their survival was ultimately influenced by their natal region. In most years, kites hatched in southern regions had greater survival probabilities than did kites hatched in northern regions. However, during a multiregional drought, one of the northern regions served as a refuge from drought, and during this perturbation, survival was greater for birds hatched in the north. Our study shows that natal location may be important in influencing the ecological dynamics of kites but also highlights the importance of considering temporal variation in habitat conditions of spatially structured systems when attempting to evaluate the conservation value of habitats.

  11. Visuospatial Asymmetries Arise from Differences in the Onset Time of Perceptual Evidence Accumulation.

    PubMed

    Newman, Daniel P; Loughnane, Gerard M; Kelly, Simon P; O'Connell, Redmond G; Bellgrove, Mark A

    2017-03-22

    Healthy subjects tend to exhibit a bias of visual attention whereby left hemifield stimuli are processed more quickly and accurately than stimuli appearing in the right hemifield. It has long been held that this phenomenon arises from the dominant role of the right cerebral hemisphere in regulating attention. However, methods that would enable more precise understanding of the mechanisms underpinning visuospatial bias have remained elusive. We sought to finely trace the temporal evolution of spatial biases by leveraging a novel bilateral dot motion detection paradigm. In combination with electroencephalography, this paradigm enables researchers to isolate discrete neural signals reflecting the key neural processes needed for making these detection decisions. These include signals for spatial attention, early target selection, evidence accumulation, and motor preparation. Using this method, we established that three key neural markers accounted for unique between-subject variation in visuospatial bias: hemispheric asymmetry in posterior α power measured before target onset, which is related to the distribution of preparatory attention across the visual field; asymmetry in the peak latency of the early N2c target-selection signal; and, finally, asymmetry in the onset time of the subsequent neural evidence-accumulation process with earlier onsets for left hemifield targets. Our development of a single paradigm to dissociate distinct processing components that track the temporal evolution of spatial biases not only advances our understanding of the neural mechanisms underpinning normal visuospatial attention bias, but may also in the future aid differential diagnoses in disorders of spatial attention. SIGNIFICANCE STATEMENT The significance of this research is twofold. First, it shows that individual differences in how humans direct their attention between left and right space reflects physiological differences in how early the brain starts to accumulate evidence for the existence of a visual target. Second, the novel methods developed here may have particular relevance to disorders of attention, such as unilateral spatial neglect. In the case of spatial neglect, pathological inattention to left space could have multiple underlying causes, including biased attention, impaired decision formation, or a motor deficit related to one side of space. Our development of a single paradigm to dissociate each of these components may aid in supporting more precise differential diagnosis in such heterogeneous disorders. Copyright © 2017 the authors 0270-6474/17/373378-08$15.00/0.

  12. Macrolichens as biomonitors of air-quality change in western Pennsylvania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McClenahen, J.R.; Davis, D.D.; Hutnik, R.J.

    2007-07-01

    Species richness of corticolous macrolichens was monitored at one- or two-year intervals on a total of 63 plots from 1997-2003 in a region of west-central Pennsylvania that included four coal-fired power generating stations and an industrial city. Lichen richness significantly increased from an average of 5.7 species/plot in 1997 to 9.3 species/plot in 2003. A linear mean rate of gain in species on regional monitoring plots was 0.56 species/yr. Plots along a major ridge top had a slower but significant gain in richness, and a localized area flanked by the city and two generating stations exhibited less lichen recolonization. Ourmore » results confirm the value of macrolichens as indicators of air quality and the importance of examining temporal as well as spatial changes in lichen richness to ascertain air-quality status.« less

  13. Determining light requirements of groundcover plants from subtropical natural forest using hemispherical photography

    NASA Astrophysics Data System (ADS)

    Zhang, Yi; Zhong, Yonglin; Xu, Mingfeng; Su, Zhiyao

    2017-01-01

    In order to determine light requirements of indigenous groundcover plants for potential use in urban landscaping, we conducted a plant census in Yinpingshan Nature Reserve, Dongguan, China, and measured canopy structure and understory light regimes using hemispherical photography. We found that canopy openness, transmitted direct solar radiation, and transmitted diffuse solar radiation exhibited highly significant spatial heterogeneity. Species composition and diversity of groundcover plants were highly dependent on canopy structure and understory light condition. Greater diversity and more stems of groundcover plants were associated with greater canopy openness and understory radiation in most cases. Highly significant differences in species composition were detected along canopy openness, transmitted direct solar radiation, and transmitted diffuse solar radiation gradients, respectively. We also detected indicator species for specific understory light regimes, which will provide useful information when applying such species in urban greening under various light environments.

  14. New York harbor water-quality survey, 1988-1990. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brosnan, T.M.

    1991-08-27

    Fifty two stations were monitored over twelve weeks of each of the summers of 1988 through 1990 to provide the 79th, 80th, and 81st Annual Summer Water Quality Surveys of New York Harbor. Coliform bacteria continue to exhibit significant long-term improvements throughout the harbor due to water pollution control plant construction and upgrades. Only 4% of stations were out of compliance with coliform standards in 1990, with exceedances confined to waterways heavily impacted by combined sewer overflows (CSO's). In 1990, average summer dissolved oxygen (DO) met state standards at 94% of surface, and 85% of bottom sites; however many sitesmore » contravened DO standards at least once. While average DO compliance in 1990 was significantly better than any time since at least 1986, 1988 and 1989 were noticeably worse, particularly in waterways prone to phytoplankton blooms and density stratification. Nutrient and chlorophyll a concentrations displayed spatial trends.« less

  15. Differential Processing of Consonance and Dissonance within the Human Superior Temporal Gyrus.

    PubMed

    Foo, Francine; King-Stephens, David; Weber, Peter; Laxer, Kenneth; Parvizi, Josef; Knight, Robert T

    2016-01-01

    The auditory cortex is well-known to be critical for music perception, including the perception of consonance and dissonance. Studies on the neural correlates of consonance and dissonance perception have largely employed non-invasive electrophysiological and functional imaging techniques in humans as well as neurophysiological recordings in animals, but the fine-grained spatiotemporal dynamics within the human auditory cortex remain unknown. We recorded electrocorticographic (ECoG) signals directly from the lateral surface of either the left or right temporal lobe of eight patients undergoing neurosurgical treatment as they passively listened to highly consonant and highly dissonant musical chords. We assessed ECoG activity in the high gamma (γhigh, 70-150 Hz) frequency range within the superior temporal gyrus (STG) and observed two types of cortical sites of interest in both hemispheres: one type showed no significant difference in γhigh activity between consonant and dissonant chords, and another type showed increased γhigh responses to dissonant chords between 75 and 200 ms post-stimulus onset. Furthermore, a subset of these sites exhibited additional sensitivity towards different types of dissonant chords, and a positive correlation between changes in γhigh power and the degree of stimulus roughness was observed in both hemispheres. We also observed a distinct spatial organization of cortical sites in the right STG, with dissonant-sensitive sites located anterior to non-sensitive sites. In sum, these findings demonstrate differential processing of consonance and dissonance in bilateral STG with the right hemisphere exhibiting robust and spatially organized sensitivity toward dissonance.

  16. Differential Processing of Consonance and Dissonance within the Human Superior Temporal Gyrus

    PubMed Central

    Foo, Francine; King-Stephens, David; Weber, Peter; Laxer, Kenneth; Parvizi, Josef; Knight, Robert T.

    2016-01-01

    The auditory cortex is well-known to be critical for music perception, including the perception of consonance and dissonance. Studies on the neural correlates of consonance and dissonance perception have largely employed non-invasive electrophysiological and functional imaging techniques in humans as well as neurophysiological recordings in animals, but the fine-grained spatiotemporal dynamics within the human auditory cortex remain unknown. We recorded electrocorticographic (ECoG) signals directly from the lateral surface of either the left or right temporal lobe of eight patients undergoing neurosurgical treatment as they passively listened to highly consonant and highly dissonant musical chords. We assessed ECoG activity in the high gamma (γhigh, 70–150 Hz) frequency range within the superior temporal gyrus (STG) and observed two types of cortical sites of interest in both hemispheres: one type showed no significant difference in γhigh activity between consonant and dissonant chords, and another type showed increased γhigh responses to dissonant chords between 75 and 200 ms post-stimulus onset. Furthermore, a subset of these sites exhibited additional sensitivity towards different types of dissonant chords, and a positive correlation between changes in γhigh power and the degree of stimulus roughness was observed in both hemispheres. We also observed a distinct spatial organization of cortical sites in the right STG, with dissonant-sensitive sites located anterior to non-sensitive sites. In sum, these findings demonstrate differential processing of consonance and dissonance in bilateral STG with the right hemisphere exhibiting robust and spatially organized sensitivity toward dissonance. PMID:27148011

  17. [Spatial and temporal variations of hydrological characteristic on the landscape zone scale in alpine cold region].

    PubMed

    Yang, Yong-Gang; Hu, Jin-Fei; Xiao, Hong-Lang; Zou, Song-Bing; Yin, Zhen-Liang

    2013-10-01

    There are few studies on the hydrological characteristics on the landscape zone scale in alpine cold region at present. This paper aimed to identify the spatial and temporal variations in the origin and composition of the runoff, and to reveal the hydrological characteristics in each zone, based on the isotopic analysis of glacier, snow, frozen soil, groundwater, etc. The results showed that during the wet season, heavy precipitation and high temperature in the Mafengou River basin caused secondary evaporation which led to isotope fractionation effects. Therefore, the isotope values remained high. Temperature effects were significant. During the dry season, the temperature was low. Precipitation was in the solid state during the cold season and the evaporation was weak. Water vapor came from the evaporation of local water bodies. Therefore, less secondary evaporation and water vapor exchange occurred, leading to negative values of delta18O and deltaD. delta18O and deltaD values of precipitation and various water bodies exhibited strong seasonal variations. Precipitation exhibited altitude effects, delta18O = -0. 005 2H - 8. 951, deltaD = -0.018 5H - 34. 873. Other water bodies did not show altitude effects in the wet season and dry season, because the runoff was not only recharged by precipitation, but also influenced by the freezing and thawing process of the glacier, snow and frozen soil. The mutual transformation of precipitation, melt water, surface water and groundwater led to variations in isotopic composition. Therefore, homogenization and evaporation effect are the main control factors of isotope variations.

  18. Temporal and spatial variation of maximum wind speed days during the past 20 years in major cities of Xinjiang

    NASA Astrophysics Data System (ADS)

    Baidourela, Aliya; Jing, Zhen; Zhayimu, Kahaer; Abulaiti, Adili; Ubuli, Hakezi

    2018-04-01

    Wind erosion and sandstorms occur in the neighborhood of exposed dust sources. Wind erosion and desertification increase the frequency of dust storms, deteriorate air quality, and damage the ecological environment and agricultural production. The Xinjiang region has a relatively fragile ecological environment. Therefore, the study of the characteristics of maximum wind speed and wind direction in this region is of great significance to disaster prevention and mitigation, the management of activated dunes, and the sustainable development of the region. Based on the latest data of 71 sites in Xinjiang, this study explores the temporal evolution and spatial distribution of maximum wind speed in Xinjiang from 1993 to 2013, and highlights the distribution of annual and monthly maximum wind speed and the characteristics of wind direction in Xinjiang. Between 1993 and 2013, Ulugchat County exhibited the highest number of days with the maximum wind speed (> 17 m/s), while Wutian exhibited the lowest number. In Xinjiang, 1999 showed the highest number of maximum wind speed days (257 days), while 2013 showed the lowest number (69 days). Spring and summer wind speeds were greater than those in autumn and winter. There were obvious differences in the direction of maximum wind speed in major cities and counties of Xinjiang. East of the Tianshan Mountains, maximum wind speeds are mainly directed southeast and northeast. North and south of the Tianshan Mountains, they are mainly directed northwest and northeast, while west of the Tianshan Mountains, they are mainly directed southeast and northwest.

  19. Chromatic and Achromatic Spatial Resolution of Local Field Potentials in Awake Cortex

    PubMed Central

    Jansen, Michael; Li, Xiaobing; Lashgari, Reza; Kremkow, Jens; Bereshpolova, Yulia; Swadlow, Harvey A.; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-01-01

    Local field potentials (LFPs) have become an important measure of neuronal population activity in the brain and could provide robust signals to guide the implant of visual cortical prosthesis in the future. However, it remains unclear whether LFPs can detect weak cortical responses (e.g., cortical responses to equiluminant color) and whether they have enough visual spatial resolution to distinguish different chromatic and achromatic stimulus patterns. By recording from awake behaving macaques in primary visual cortex, here we demonstrate that LFPs respond robustly to pure chromatic stimuli and exhibit ∼2.5 times lower spatial resolution for chromatic than achromatic stimulus patterns, a value that resembles the ratio of achromatic/chromatic resolution measured with psychophysical experiments in humans. We also show that, although the spatial resolution of LFP decays with visual eccentricity as is also the case for single neurons, LFPs have higher spatial resolution and show weaker response suppression to low spatial frequencies than spiking multiunit activity. These results indicate that LFP recordings are an excellent approach to measure spatial resolution from local populations of neurons in visual cortex including those responsive to color. PMID:25416722

  20. Common Neural Representations for Visually Guided Reorientation and Spatial Imagery

    PubMed Central

    Vass, Lindsay K.; Epstein, Russell A.

    2017-01-01

    Abstract Spatial knowledge about an environment can be cued from memory by perception of a visual scene during active navigation or by imagination of the relationships between nonvisible landmarks, such as when providing directions. It is not known whether these different ways of accessing spatial knowledge elicit the same representations in the brain. To address this issue, we scanned participants with fMRI, while they performed a judgment of relative direction (JRD) task that required them to retrieve real-world spatial relationships in response to either pictorial or verbal cues. Multivoxel pattern analyses revealed several brain regions that exhibited representations that were independent of the cues to access spatial memory. Specifically, entorhinal cortex in the medial temporal lobe and the retrosplenial complex (RSC) in the medial parietal lobe coded for the heading assumed on a particular trial, whereas the parahippocampal place area (PPA) contained information about the starting location of the JRD. These results demonstrate the existence of spatial representations in RSC, ERC, and PPA that are common to visually guided navigation and spatial imagery. PMID:26759482

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