32 CFR 1900.02 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... institution engaged in research concerning the social, biological, or physical sciences or an instructor or... descriptive terms which permit an Agency employee to locate documents with reasonable effort given existing...

32 CFR 1900.02 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... institution engaged in research concerning the social, biological, or physical sciences or an instructor or... descriptive terms which permit an Agency employee to locate documents with reasonable effort given existing...

32 CFR 1900.02 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... institution engaged in research concerning the social, biological, or physical sciences or an instructor or... descriptive terms which permit an Agency employee to locate documents with reasonable effort given existing...

Enabling scientific teamwork

NASA Astrophysics Data System (ADS)

Hereld, Mark; Hudson, Randy; Norris, John; Papka, Michael E.; Uram, Thomas

2009-07-01

The Computer Supported Collaborative Work research community has identified that the technology used to support distributed teams of researchers, such as email, instant messaging, and conferencing environments, are not enough. Building from a list of areas where it is believed technology can help support distributed teams, we have divided our efforts into support of asynchronous and synchronous activities. This paper will describe two of our recent efforts to improve the productivity of distributed science teams. One effort focused on supporting the management and tracking of milestones and results, with the hope of helping manage information overload. The second effort focused on providing an environment that supports real-time analysis of data. Both of these efforts are seen as add-ons to the existing collaborative infrastructure, developed to enhance the experience of teams working at a distance by removing barriers to effective communication.

77 FR 3781 - Pediatric Medical Devices; Public Workshop; Reopening of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-25

... discussion of how to determine when it is appropriate to use, and how to use, existing scientific research... use of scientific research data to support pediatric medical device efficacy claims. This is part of an on-going effort to address the ways scientific research data can be used to support pediatric...

How Small School Districts Can Organize to Afford Their Small Schools

ERIC Educational Resources Information Center

Burton, Christine

2010-01-01

While the research continues to mount on the benefits of school downsizing and decentralizing efforts in urban areas, there exists a paradox for small school Administrators who continue to struggle against forces of consolidation. Small schools in rural and suburban districts have fought for their existence against the pressures of consolidation…

Response to ERIS 2014 States' Research Needs Survey

EPA Science Inventory

This document is ORD’s response to the states’ needs and priorities, as identified in the 2014 survey. ORD identified existing methods, models, tools and databases on these topics, as well as near-term research and development efforts, that could assist states in thei...

Institute for Scientific and Educational Technology (ISET)-Education, Research and Training Programs in Engineering and Sciences

NASA Technical Reports Server (NTRS)

Tiwari, S. N. (Principal Investigator); Massenberg, Samuel E. (Technical Monitor)

2002-01-01

The 'Institute for Scientific and Educational Technology' has been established to provide a mechanism through which universities and other research organizations may cooperate with one another and with different government agencies and industrial organizations to further and promote research, education, and training programs in science, engineering, and related fields. This effort has been undertaken consistent with the national vision to 'promote excellence in America s educational system through enhancing and expanding scientific and technological competence.' The specific programs are directed in promoting and achieving excellence for individuals at all levels (elementary and secondary schools, undergraduate and graduate education, and postdoctoral and faculty research). The program is consistent with the existing activities of the Institute for Computational and Applied Mechanics (ICAM) and the American Society for Engineering Education (ASEE) at NASA Langley Research Center (LaRC). The efforts will be directed to embark on other research, education, and training activities in various fields of engineering, scientific, and educational technologies. The specific objectives of the present program may be outlined briefly as follows: 1) Cooperate in the various research, education, and technology programs of the Office of Education at LaRC. 2) Develop procedures for interactions between precollege, college, and graduate students, and between faculty and students at all levels. 3) Direct efforts to increase the participation by women and minorities in educational programs at all levels. 4) Enhance existing activities of ICAM and ASEE in education, research, and training of graduate students and faculty. 5) Invite distinguished scholars as appropriate and consistent with ISET goals to spend their summers and/or sabbaticals at NASA Langley andor ODU and interact with different researchers and graduate students. Perform research and administrative activities as needed to carry out the above mentioned activities. 6) The implementation of various activities of the ISET programs is carried out through cooperative efforts between Old Dominion University (ODU) and the Office of Education at LaRC. At present, major efforts are directed on the following ISET Programs: ICAM Programs, Academic Programs, Educational Research, Outreach Programs, Educational Technology and Cooperative Programs. These programs are described in the following sections.

Spacecraft contamination programs within the Air Force Systems Command Laboratories

NASA Technical Reports Server (NTRS)

Murad, Edmond

1990-01-01

Spacecraft contamination programs exist in five independent AFSC organizations: Geophysics Laboratory (GL), Arnold Engineering and Development Center (AEDC), Rome Air Development Center (RADC/OSCE), Wright Research and Development Center (MLBT), Armament Laboratory (ATL/SAI), and Space Systems Division (SSD/OL-AW). In addition, a sizable program exists at Aerospace Corp. These programs are complementary, each effort addressing a specific area of expertise: GL's effort is aimed at addressing the effects of on-orbit contamination; AEDC's effort is aimed at ground simulation and measurement of optical contamination; RADC's effort addresses the accumulation, measurement, and removal of contamination on large optics; MLBT's effort is aimed at understanding the effect of contamination on materials; ATL's effort is aimed at understanding the effect of plume contamination on systems; SSD's effort is confined to the integration of some contamination experiments sponsored by SSD/CLT; and Aerospace Corp.'s effort is aimed at supporting the needs of the using System Program Offices (SPO) in specific areas, such as contamination during ground handling, ascent phase, laboratory measurements aimed at understanding on-orbit contamination, and mass loss and mass gain in on-orbit operations. These programs are described in some detail, with emphasis on GL's program.

Data standards for clinical research data collection forms: current status and challenges.

PubMed

Richesson, Rachel L; Nadkarni, Prakash

2011-05-01

Case report forms (CRFs) are used for structured-data collection in clinical research studies. Existing CRF-related standards encompass structural features of forms and data items, content standards, and specifications for using terminologies. This paper reviews existing standards and discusses their current limitations. Because clinical research is highly protocol-specific, forms-development processes are more easily standardized than is CRF content. Tools that support retrieval and reuse of existing items will enable standards adoption in clinical research applications. Such tools will depend upon formal relationships between items and terminological standards. Future standards adoption will depend upon standardized approaches for bridging generic structural standards and domain-specific content standards. Clinical research informatics can help define tools requirements in terms of workflow support for research activities, reconcile the perspectives of varied clinical research stakeholders, and coordinate standards efforts toward interoperability across healthcare and research data collection.

Case Studies in Describing Scientific Research Efforts as Linked Data

NASA Astrophysics Data System (ADS)

Gandara, A.; Villanueva-Rosales, N.; Gates, A.

2013-12-01

The Web is growing with numerous scientific resources, prompting increased efforts in information management to consider integration and exchange of scientific resources. Scientists have many options to share scientific resources on the Web; however, existing options provide limited support to scientists in annotating and relating research resources resulting from a scientific research effort. Moreover, there is no systematic approach to documenting scientific research and sharing it on the Web. This research proposes the Collect-Annotate-Refine-Publish (CARP) Methodology as an approach for guiding documentation of scientific research on the Semantic Web as scientific collections. Scientific collections are structured descriptions about scientific research that make scientific results accessible based on context. In addition, scientific collections enhance the Linked Data data space and can be queried by machines. Three case studies were conducted on research efforts at the Cyber-ShARE Research Center of Excellence in order to assess the effectiveness of the methodology to create scientific collections. The case studies exposed the challenges and benefits of leveraging the Semantic Web and Linked Data data space to facilitate access, integration and processing of Web-accessible scientific resources and research documentation. As such, we present the case study findings and lessons learned in documenting scientific research using CARP.

Inter- and Transdisciplinary Work: Connecting Research on Hormones with Problems of Educational Practice

ERIC Educational Resources Information Center

Rappolt-Schlichtmann, Gabrielle; Watamura, Sarah E.

2010-01-01

More than ever before, leaders within the field of education are looking to research on basic processes to inform and improve educational practices. Success requires building a reciprocal relationship between the field of education and research on learning and development, similar to what exists between biology and medicine. Key to this effort is…

Ontology Extraction Tools: An Empirical Study with Educators

ERIC Educational Resources Information Center

Hatala, M.; Gasevic, D.; Siadaty, M.; Jovanovic, J.; Torniai, C.

2012-01-01

Recent research in Technology-Enhanced Learning (TEL) demonstrated several important benefits that semantic technologies can bring to the TEL domain. An underlying assumption for most of these research efforts is the existence of a domain ontology. The second unspoken assumption follows that educators will build domain ontologies for their…

Nuclear Physics Research Activity Today in the World and in Brazil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lepine-Szily, Alinka

2009-06-03

The international effort in Nuclear Physics is described, including informations on working force, its evolution, budgets, existing, new and projected facilities. The main goals of this research and its recent achievements are also presented. The specific informations on Brazil are also highlighted in the presentation.

A Scholar-Practitioner Perspective to Promoting Minority Success in STEM

ERIC Educational Resources Information Center

Covington, Megan; Chavis, Terry; Perry, April

2017-01-01

Purpose: The purpose of this conceptual paper is to present the existing research on already effective programmatic efforts designed to increase diversity in STEM fields and to subsequently encourage researchers and practitioners to more intentionally build upon and design effective interventions around this issue. Design/methodology/approach:…

Religion and Spirituality within Counselling/Clinical Psychology Training Programmes: A Systematic Review

ERIC Educational Resources Information Center

Jafari, Simon

2016-01-01

In recent years, there have been increasing efforts to attend to religious and spiritual issues within clinical/counselling psychology. However, there is limited research demonstrating how successfully such content is integrated into existing training programmes. This investigation sought to review primary research literature related to training…

Leveraging Crowdsourcing and Linked Open Data for Geoscience Data Sharing and Discovery

NASA Astrophysics Data System (ADS)

Narock, T. W.; Rozell, E. A.; Hitzler, P.; Arko, R. A.; Chandler, C. L.; Wilson, B. D.

2013-12-01

Data citation standards can form the basis for increased incentives, recognition, and rewards for scientists. Additionally, knowing which data were utilized in a particular publication can enhance discovery and reuse. Yet, a lack of data citation information in existing publications as well as ambiguities across datasets can limit the accuracy of automated linking approaches. We describe a crowdsourcing approach, based on Linked Open Data, in which AGU abstracts are linked to the data used in those presentations. We discuss our efforts to incentivize participants through promotion of their research, the role that the Semantic Web can play in this effort, and how this work differs from existing platforms such as Mendeley and ResearchGate. Further, we discuss the benefits and challenges of Linked Open Data as a technical solution including the role of provenance, trust, and computational reasoning.

Towards identifying the next generation of superfund and hazardous waste site contaminants

USGS Publications Warehouse

Ela, Wendell P.; Sedlak, David L.; Barlaz, Morton A.; Henry, Heather F.; Muir, Derek C.G.; Swackhamer, Deborah L.; Weber, Eric J.; Arnold, Robert G.; Ferguson, P. Lee; Field, Jennifer A.; Furlong, Edward T.; Giesy, John P.; Halden, Rolf U.; Henry, Tala; Hites, Ronald A.; Hornbuckle, Keri C.; Howard, Philip H.; Luthy, Richard G.; Meyer, Anita K.; Saez, A. Eduardo; vom Saal, Frederick S.; Vulpe, Chris D.; Wiesner, Mark R.

2011-01-01

Conclusions A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention.

A GIS-based framework for evaluating investments in fire management: Spatial allocation of recreation values

Treesearch

Kenneth A. Baerenklau; Armando González-Cabán; Catrina I. Páez; Edgard Chávez

2009-01-01

The U.S. Forest Service is responsible for developing tools to facilitate effective and efficient fire management on wildlands and urban-wildland interfaces. Existing GIS-based fire modeling software only permits estimation of the costs of fire prevention and mitigation efforts as well as the effects of those efforts on fire behavior. This research demonstrates how the...

Toward Understanding the Potential of Games for Learning: Learning Theory, Game Design Characteristics, and Situating Video Games in Classrooms

ERIC Educational Resources Information Center

Turkay, Selen; Hoffman, Daniel; Kinzer, Charles K.; Chantes, Pantiphar; Vicari, Christopher

2014-01-01

Researchers have argued that an effort should be made to raise teachers' and parents' awareness of the potentially positive educational benefits of playing video games (e.g., see Baek, 2008). One part of this effort should be to increase understanding of how video games can be situated within teachers' existing goals and knowledge…

A flexible telerobotic system for space operations

NASA Technical Reports Server (NTRS)

Sliwa, N. O.; Will, R. W.

1987-01-01

The objective and design of a proposed goal-oriented knowledge-based telerobotic system for space operations is described. This design effort encompasses the elements of the system executive and user interface and the distribution and general structure of the knowledge base, the displays, and the task sequencing. The objective of the design effort is to provide an expandable structure for a telerobotic system that provides cooperative interaction between the human operator and computer control. The initial phase of the implementation provides a rule-based, goal-oriented script generator to interface to the existing control modes of a telerobotic research system, in the Intelligent Systems Research Lab at NASA Research Center.

Show me the numbers: What data currently exist for non-native species in the USA?

USGS Publications Warehouse

Crall, Alycia W.; Meyerson, Laura A.; Stohlgren, Thomas J.; Jarnevich, Catherine S.; Newman, Gregory J.; Graham, James

2006-01-01

Non-native species continue to be introduced to the United States from other countries via trade and transportation, creating a growing need for early detection and rapid response to new invaders. It is therefore increasingly important to synthesize existing data on non-native species abundance and distributions. However, no comprehensive analysis of existing data has been undertaken for non-native species, and there have been few efforts to improve collaboration. We therefore conducted a survey to determine what datasets currently exist for non-native species in the US from county, state, multi-state region, national, and global scales. We identified 319 datasets and collected metadata for 79% of these. Through this study, we provide a better understanding of extant non-native species datasets and identify data gaps (ie taxonomic, spatial, and temporal) to help guide future survey, research, and predictive modeling efforts.

Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions.

PubMed

Becker, Sara J

2015-03-01

The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed.

Identifying the Role of the International Consortium ``MIT/ LINC'' in Supporting the Integration of ICT in Higher Education in Emerging Countries

NASA Astrophysics Data System (ADS)

Park, Young; Moser, Franziska Zellweger

2008-04-01

The goal of this research effort is to provide insights on what core needs and difficulties exist toward the implementation of ICT in higher education in emerging countries and how a consortium like LINC can best support these efforts. An exploratory research design combining a survey, on-site interviews, participant observation and document analysis were employed to answer the research questions. Main challenges in establishing technology- based learning environments were identified in the area of pedagogies, finances, technological infrastructure, cultural change, organization, and management. LINC, as an non-political organization embedded in an academic environment, can take an important role in facilitating the dialogue among participants through various platforms, take an active role in promoting joint programs and assist with efforts to "localize" tools and practice.

The Role of Research in Online Curriculum Development: The Case of "EarthLabs" Climate Change and Earth System Modules

ERIC Educational Resources Information Center

McNeal, Karen S.; Libarkin, Julie C.; Ledley, Tamara Shapiro; Bardar, Erin; Haddad, Nick; Elins, Kathy; Dutta, Saranee

2014-01-01

This study reports on an effort to illustrate the coupling of educational research with ongoing curriculum development to promote effective and evidence-based online learning. The research findings have been used to inform the "EarthLabs" curriculum development team as they revise existing modules and create new modules, in order to…

Development of breeding populations of rhesus macaques (Macaca mulatta) that are specific pathogen-free for rhesus cytomegalovirus.

PubMed

Barry, Peter A; Strelow, Lisa

2008-02-01

Development of breeding colonies of rhesus macaques (Macaca mulatta) that are specific pathogen-free (SPF) for rhesus cytomegalovirus (RhCMV) is relatively straightforward and requires few modifications from current SPF programs. Infants separated from the dam at or within a few days of birth and cohoused with similarly treated animals remain RhCMV seronegative indefinitely, provided they are never directly or indirectly exposed to a RhCMV-infected monkey. By systematically cohousing seronegative animals into larger social cohorts, breeding populations of animals SPF for RhCMV can be established. The additional costs involved in expanding the current definition of SPF status to include RhCMV are incremental compared with the money already being spent on existing SPF efforts. Moreover, the large increase in research opportunities available for RhCMV-free animals arguably would far exceed the development costs. Potential new areas of research and further expansion of existing research efforts involving these newly defined SPF animals would have direct implications for improvements in human health.

Health information technology needs help from primary care researchers.

PubMed

Krist, Alex H; Green, Lee A; Phillips, Robert L; Beasley, John W; DeVoe, Jennifer E; Klinkman, Michael S; Hughes, John; Puro, Jon; Fox, Chester H; Burdick, Tim

2015-01-01

While health information technology (HIT) efforts are beginning to yield measurable clinical benefits, more is needed to meet the needs of patients and clinicians. Primary care researchers are uniquely positioned to inform the evidence-based design and use of technology. Research strategies to ensure success include engaging patient and clinician stakeholders, working with existing practice-based research networks, and using established methods from other fields such as human factors engineering and implementation science. Policies are needed to help support primary care researchers in evaluating and implementing HIT into everyday practice, including expanded research funding, strengthened partnerships with vendors, open access to information systems, and support for the Primary Care Extension Program. Through these efforts, the goal of improved outcomes through HIT can be achieved. © Copyright 2015 by the American Board of Family Medicine.

Retroreflectivity of existing signs in Pennsylvania.

DOT National Transportation Integrated Search

2012-04-01

The Pennsylvania Department of Transportation (PennDOT) Bureau of Highway Safety and Traffic Engineering initiated this : research effort in response to the release of the new 2009 Manual on Uniform Traffic Control Devices (MUTCD) which mandates : th...

Male Dance Educators in a Female-Dominated Profession

ERIC Educational Resources Information Center

Wright, Golden

2013-01-01

Problems in gender equity exist in dance education just as they do in other professions. There is a need for strategic recruitment efforts and research on how to attract more males into the dance profession.

Designing to Control Flight Crew Errors

NASA Technical Reports Server (NTRS)

Schutte, Paul C.; Willshire, Kelli F.

1997-01-01

It is widely accepted that human error is a major contributing factor in aircraft accidents. There has been a significant amount of research in why these errors occurred, and many reports state that the design of flight deck can actually dispose humans to err. This research has led to the call for changes in design according to human factors and human-centered principles. The National Aeronautics and Space Administration's (NASA) Langley Research Center has initiated an effort to design a human-centered flight deck from a clean slate (i.e., without constraints of existing designs.) The effort will be based on recent research in human-centered design philosophy and mission management categories. This design will match the human's model of the mission and function of the aircraft to reduce unnatural or non-intuitive interfaces. The product of this effort will be a flight deck design description, including training and procedures, and a cross reference or paper trail back to design hypotheses, and an evaluation of the design. The present paper will discuss the philosophy, process, and status of this design effort.

75 FR 69086 - Submission for OMB review; comment request; NCCAM Office of Communications and Public Liaison...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

...) formative and (2) evaluative research of a variety of print and online materials, outreach activities, and... evaluative research on existing materials and messages, as part of OCPL's ongoing effort to develop a comprehensive program of testing and evaluation of all of its communications strategies. This evaluative...

75 FR 61763 - Submission for OMB Review; Comment Request; NCCAM Office of Communications and Public Liaison...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-06

...) formative and (2) evaluative research of a variety of print and online materials, outreach activities, and... evaluative research on existing materials and messages, as part of OCPL's ongoing effort to develop a comprehensive program of testing and evaluation of all of its communications strategies. This evaluative...

Protective Factors as Barriers to Depression in Gifted and Nongifted Adolescents

ERIC Educational Resources Information Center

Mueller, Christian E.

2009-01-01

Despite continued efforts by researchers, a gap still exists in our understanding of the psychological, social, and emotional adjustment of gifted students. Historically, research and education of the gifted has focused on cognitive variables, with less attention given to the social and emotional needs of these students. The current study used…

48 CFR 235.015-70 - Special use allowances for research facilities acquired by educational institutions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... performance of DoD contracts; (2) Existing facilities, either Government or nongovernment, cannot meet program... effort which results in the special use allowance being excessive compared to the Government research... Defense contracts. FAR 31.3 governs how much the Government will reimburse the institution for the...

Job Performance Aids: Research and Technology State-of-the-Art. Final Report.

ERIC Educational Resources Information Center

Booher, Harold R.

Conducted as part of a major effort to test and evaluate Job Performance Aids (JPA) and their integration with Navy personnel and training systems, this study systematically reviewed and organized existing JPA techniques, related research data, and various applicable principles and concepts. One hundred and one JPA systems and techniques were…

Scientific integrity resource guide: Efforts by federal agencies, foundations, nonprofit organizations, professional societies, and academia in the United States

PubMed Central

Kretser, Alison; Murphy, Delia; Dwyer, Johanna

2017-01-01

ABSTRACT Scientific integrity is at the forefront of the scientific research enterprise. This paper provides an overview of key existing efforts on scientific integrity by federal agencies, foundations, nonprofit organizations, professional societies, and academia from 1989 to April 2016. It serves as a resource for the scientific community on scientific integrity work and helps to identify areas in which more action is needed. Overall, there is tremendous activity in this area and there are clear linkages among the efforts of the five sectors. All the same, scientific integrity needs to remain visible in the scientific community and evolve along with new research paradigms. High priority in instilling these values falls upon all stakeholders. PMID:27748637

Candidate R&D Thrusts for the Software Technology Initiative.

DTIC Science & Technology

1981-05-01

computer-aided design and manufacturing efforts provide examples of multiple representations and multiple manipulation modes. R&D difficulties exist in...farfetched, but the potential payoffs are enormous. References Birk, J., and R. Kelley. Research Needed to Advance the State of Knowledge in Robotics . In...and specifica- tion languages would be benefical . This R&D effort may also result in fusion with management tools with which an acquisition manager

Signal replacement with an interchange.

DOT National Transportation Integrated Search

2007-08-24

The purpose of this research effort is to evaluate unique intersection designs for their suitability for use in lieu : of an existing or proposed traffic signal. Traffic signals can cause unnecessary delay and capacity restrictions : due to the opera...

Theme II Joint Work Plan -2017 Collaboration and Knowledge Sharing on Large-scale Demonstration Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Xiaoliang; Stauffer, Philip H.

This effort is designed to expedite learnings from existing and planned large demonstration projects and their associated research through effective knowledge sharing among participants in the US and China.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weaver, C. P.; Mooney, Sian; Allen, D.

US efforts to integrate social and biophysical sciences to address the issue of global change exist within a wider movement to understand global change as a societal challenge and to inform policy. Insights from the social sciences can help transform global change research into action.

A Vision for Incorporating Environmental Effects into Nitrogen Management Decision Support Tools for U.S. Maize Production

PubMed Central

Banger, Kamaljit; Yuan, Mingwei; Wang, Junming; Nafziger, Emerson D.; Pittelkow, Cameron M.

2017-01-01

Meeting crop nitrogen (N) demand while minimizing N losses to the environment has proven difficult despite significant field research and modeling efforts. To improve N management, several real-time N management tools have been developed with a primary focus on enhancing crop production. However, no coordinated effort exists to simultaneously address sustainability concerns related to N losses at field- and regional-scales. In this perspective, we highlight the opportunity for incorporating environmental effects into N management decision support tools for United States maize production systems by integrating publicly available crop models with grower-entered management information and gridded soil and climate data in a geospatial framework specifically designed to quantify environmental and crop production tradeoffs. To facilitate advances in this area, we assess the capability of existing crop models to provide in-season N recommendations while estimating N leaching and nitrous oxide emissions, discuss several considerations for initial framework development, and highlight important challenges related to improving the accuracy of crop model predictions. Such a framework would benefit the development of regional sustainable intensification strategies by enabling the identification of N loss hotspots which could be used to implement spatially explicit mitigation efforts in relation to current environmental quality goals and real-time weather conditions. Nevertheless, we argue that this long-term vision can only be realized by leveraging a variety of existing research efforts to overcome challenges related to improving model structure, accessing field data to enhance model performance, and addressing the numerous social difficulties in delivery and adoption of such tool by stakeholders. PMID:28804490

A Vision for Incorporating Environmental Effects into Nitrogen Management Decision Support Tools for U.S. Maize Production.

PubMed

Banger, Kamaljit; Yuan, Mingwei; Wang, Junming; Nafziger, Emerson D; Pittelkow, Cameron M

2017-01-01

Meeting crop nitrogen (N) demand while minimizing N losses to the environment has proven difficult despite significant field research and modeling efforts. To improve N management, several real-time N management tools have been developed with a primary focus on enhancing crop production. However, no coordinated effort exists to simultaneously address sustainability concerns related to N losses at field- and regional-scales. In this perspective, we highlight the opportunity for incorporating environmental effects into N management decision support tools for United States maize production systems by integrating publicly available crop models with grower-entered management information and gridded soil and climate data in a geospatial framework specifically designed to quantify environmental and crop production tradeoffs. To facilitate advances in this area, we assess the capability of existing crop models to provide in-season N recommendations while estimating N leaching and nitrous oxide emissions, discuss several considerations for initial framework development, and highlight important challenges related to improving the accuracy of crop model predictions. Such a framework would benefit the development of regional sustainable intensification strategies by enabling the identification of N loss hotspots which could be used to implement spatially explicit mitigation efforts in relation to current environmental quality goals and real-time weather conditions. Nevertheless, we argue that this long-term vision can only be realized by leveraging a variety of existing research efforts to overcome challenges related to improving model structure, accessing field data to enhance model performance, and addressing the numerous social difficulties in delivery and adoption of such tool by stakeholders.

SUBTASK 6.1 – STRATEGIC STUDIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, Thomas; Harju, John; Steadman, Edward

The Energy & Environmental Research Center (EERC) has recently completed 7 years of research through the Cooperative Agreement with the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) focused on fossil energy technology development and demonstration. To support a significant number of the different activities being considered within all of our research contracts with NETL, a subtask (6.1 – Strategic Studies) was created to focus on small research efforts that came up throughout the year that would support an existing EERC–NETL project or would help to develop a new concept for inclusion in future efforts. This subtask wasmore » funded through the EERC–DOE Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FC26- 08NT43291« less

Performance Data Report: Space Medicine Division, Human Research Program, Behavioural Health and Performance Research Element

NASA Technical Reports Server (NTRS)

Shea, Camille; Keeton, Kathryn E.; Schmidt, Lacey L.; Slack, Kelley J.; Patterson, Holly N.; Leveton, Lauren B.; Holland, Albert W.

2012-01-01

This report is the result of a collaborative effort between NASA?s Behavioral Health & Performance (BHP) Research and Operations Group to investigate and determine the availability of data pertaining to behavioral performance (and other pertinent variables) that have been collected by the laboratories at NASA?s Johnson Space Center. BHP?s Operations and Research groups collaborated to systematically identify what types of performance data are needed in relevant BHP performance domains and also to conduct structured interviews with NASA personnel to identify which data do or do not exist currently (and for instances where such data exist, to evaluate the type, quality, accessibility, and confidentiality of those data). The authors defined outcome categories of performance that encapsulate BHP performance domains, mapped BHP Research Risks and Gaps onto those performance outcome categories, and identified and prioritized indicators for each outcome category. The team identified key points of contact (subject matter experts [SMEs]) as potential interviewees, created a template for structured interview questions about sources and accessibility of performance data, and coordinated and conducted structured interviews with the SMEs. The methodology, results, and implications of this effort, as well as forward work needed, are discussed in this report.

Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

PubMed Central

Becker, Sara J.

2014-01-01

The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

Collaborations in gynecologic oncology education and research in low- and middle- income countries: Current status, barriers and opportunities.

PubMed

Chuang, L; Berek, J; Randall, T; McCormack, M; Schmeler, K; Manchanda, R; Rebbeck, T; Jeng, C J; Pyle, D; Quinn, M; Trimble, E; Naik, R; Lai, C H; Ochiai, K; Denny, L; Bhatla, N

2018-08-01

Eighty-five percent of the incidents and deaths from cervical cancer occur in low and middle income countries. In many of these countries, this is the most common cancer in women. The survivals of the women with gynecologic cancers are hampered by the paucity of prevention, screening, treatment facilities and gynecologic oncology providers. Increasing efforts dedicated to improving education and research in these countries have been provided by international organizations. We describe here the existing educational and research programs that are offered by major international organizations, the barriers and opportunities provided by these collaborations and hope to improve the outcomes of cervical cancer through these efforts.

Asset Analysis and Operational Concepts for Separation Assurance Flight Testing at Dryden Flight Research Center

NASA Technical Reports Server (NTRS)

Costa, Guillermo J.; Arteaga, Ricardo A.

2011-01-01

A preliminary survey of existing separation assurance and collision avoidance advancements, technologies, and efforts has been conducted in order to develop a concept of operations for flight testing autonomous separation assurance at Dryden Flight Research Center. This effort was part of the Unmanned Aerial Systems in the National Airspace System project. The survey focused primarily on separation assurance projects validated through flight testing (including lessons learned), however current forays into the field were also examined. Comparisons between current Dryden flight and range assets were conducted using House of Quality matrices in order to allow project management to make determinations regarding asset utilization for future flight tests. This was conducted in order to establish a body of knowledge of the current collision avoidance landscape, and thus focus Dryden s efforts more effectively towards the providing of assets and test ranges for future flight testing within this research field.

The Impact of Guided Notes on Post-Secondary Student Achievement: A Meta-Analysis

ERIC Educational Resources Information Center

Larwin, Karen H.; Larwin, David A.

2013-01-01

The common practice of using of guided notes in the post-secondary classroom is not fully appreciated or understood. In an effort to add to the existing research about this phenomenon, the current investigation expands on previously published research and one previously published meta-analysis that examined the impact of guided notes on…

Developing Library GIS Services for Humanities and Social Science: An Action Research Approach

ERIC Educational Resources Information Center

Kong, Ningning; Fosmire, Michael; Branch, Benjamin Dewayne

2017-01-01

In the academic libraries' efforts to support digital humanities and social science, GIS service plays an important role. However, there is no general service model existing about how libraries can develop GIS services to best engage with digital humanities and social science. In this study, we adopted the action research method to develop and…

Analysis of Students' Self-Efficacy, Interest, and Effort Beliefs in General Chemistry

ERIC Educational Resources Information Center

Ferrell, Brent; Barbera, Jack

2015-01-01

Research in academic motivation has highlighted a number of salient constructs that are predictive of positive learning strategies and academic success. Most of this research has centered on college-level social sciences or secondary school student populations. The main purpose of this study was to adapt existing measures of personal interest and…

Intervening in Bullying: Differences across Elementary School Staff Members in Attitudes, Perceptions, and Self-Efficacy Beliefs

ERIC Educational Resources Information Center

Williford, Anne

2015-01-01

Although a growing body of research has investigated the experiences of certified school staff in antibullying efforts, a dearth of research exists on noncertified staff. To that end, the present study examined differences in attitudes, perceptions, and self-efficacy beliefs to intervene among certified (for example, teachers, counselors, school…

Advanced Command Destruct System (ACDS) Enhanced Flight Termination System (EFTS)

NASA Technical Reports Server (NTRS)

Tow, David K.

2011-01-01

This presentation provides information on the development, integration, and operational usage of the Enhanced Flight Termination System (EFTS) at NASA Dryden Flight Research Center and Air Force Flight Test Center. The presentation will describe the efforts completed to certify the system and acquire approval for operational usage, the efforts to integrate the system into the NASA Dryden existing flight termination infrastructure, and the operational support of aircraft with EFTS at Edwards AFB.

We Don't Need a "Geoengineering" Research Program

NASA Astrophysics Data System (ADS)

Caldeira, K.

2011-12-01

Most approaches commonly labeled as 'geoengineering' can be divided into two categories: approaches that attempt to reduce the change in atmospheric composition caused by anthropogenic emissions (commonly labeled CDR, for Carbon Dioxide Removal), and approaches that attempt to reduce the change in climate caused by changes in atmospheric composition (commonly labeled SRM, for Sunlight Reflection Methods or Solar Radiation Management). CDR is relatively uncontroversial (apart from ocean fertilization), and the primary issues are typically cost, effectiveness, local environmental consequences, and verification. In contrast, SRM has provoked much controversy, because large-scale SRM deployments necessarily would affect everyone on this planet. Several proposals have been tabled for SRM-specific or geoengineering-specific research and governance structures, treating SRM or geoengineering research as a thing apart. We should instead view CDR and SRM research as part of a broader continuum of activities aimed at understanding Earth system dynamics and reducing risks associated with climate change. The scope of existing research efforts should be broadened so that CDR and SRM approaches are, at this stage in development, treated as an extension of what we are already doing. What is 'geoengineering research'? A primary need at this time is for expansion of scope of and funding for existing climate-related research efforts. For examples: Scientists studying the role of aerosols in clouds or stratospheric processes can expand the domain of concern to consider effects of intentionally introduced aerosols (and not just natural aerosols and aerosols we introduce as a byproduct of civilization's normal functioning). Scientists studying effects of land-surface change on global and regional climates can expand the domain of concern beyond inadvertent effects to consider effects of land-surface changes undertaken with the intent to affect these climates. Research programs aimed at removing carbon dioxide from power plant flue gases can be broadened to consider industrial approaches to remove carbon dioxide that has already been released to the atmosphere. There appears to be little need for new overarching research structures or institutions at this time for activities for which there are no plans for deployment. Defining the scope of reference of 'geoengineering' and related terms (eg, 'geoengineering experiment') is a linguistic distraction and a waste of time. We should focus instead on substantive issues of primary concern. If our goal is to reduce risk from scientific experiments, then let's develop approaches aimed at governing risky experiments. Governance efforts can be aimed at eliminating unjustified risk independently of whether some people might want to apply labels like 'geoengineering' to those activities. We do not need 'a geoengineering research program'. We need to expand existing research programs to consider a broader range of activities and conditions. We do not need efforts to govern 'geoengineering experiments' although we may need efforts to govern scientific experiments that pose unjustified risks. Let's focus on gaining knowledge and managing risks, and not let our brains be addled by emotionally-charged language.

FY16 Status Report on NEAMS Neutronics Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, C. H.; Shemon, E. R.; Smith, M. A.

2016-09-30

The goal of the NEAMS neutronics effort is to develop a neutronics toolkit for use on sodium-cooled fast reactors (SFRs) which can be extended to other reactor types. The neutronics toolkit includes the high-fidelity deterministic neutron transport code PROTEUS and many supporting tools such as a cross section generation code MC 2-3, a cross section library generation code, alternative cross section generation tools, mesh generation and conversion utilities, and an automated regression test tool. The FY16 effort for NEAMS neutronics focused on supporting the release of the SHARP toolkit and existing and new users, continuing to develop PROTEUS functions necessarymore » for performance improvement as well as the SHARP release, verifying PROTEUS against available existing benchmark problems, and developing new benchmark problems as needed. The FY16 research effort was focused on further updates of PROTEUS-SN and PROTEUS-MOCEX and cross section generation capabilities as needed.« less

Bridging the research-practice gap: breaking new ground in health care.

PubMed

Mulhall, A

2001-08-01

Many theorists have discussed the existence of a gap between nursing research and practice. Consequently much time and effort has been expended in trying to devise strategies to bridge this divide. This article explores what the research-practice gap is and discusses five important reasons for it. The issue is then raised as to whether or not there is a gap between evidence and practice, despite the existence of the gap between research and practice. This is explored in relation to the potential conflict between the 'know how' knowledge important in practice and the 'know that' knowledge important in academia. Finally, the concept of practitioner-centred research is described as one strategy that would effectively obliterate the research-practice gap as it is currently conceived.

Rethinking our approach to gender and disasters: Needs, responsibilities, and solutions.

PubMed

Montano, Samantha; Savitt, Amanda

2016-01-01

To explore how the existing literature has discussed the vulnerability and needs of women in a disaster context. It will consider the literature's suggestions of how to minimize vulnerability and address the needs of women, including who involved in emergency management should be responsible for such efforts. Empirical journal articles and book chapters from disaster literature were collected that focused on "women" or "gender," and their results and recommendations were analyzed. This review found existing empirical research on women during disasters focuses on their vulnerabilities more than their needs. Second, when researchers do suggest solutions, they tend not to be comprehensive or supported by empirical evidence. Finally, it is not clear from existing research who is responsible for addressing these needs and implementing solutions. Future research should study the intersection of gender and disasters in terms of needs and solutions including who is responsible for implementing solutions.

Environmental digital data repositories project : final report, June 22, 2009.

DOT National Transportation Integrated Search

2010-06-22

This research body of work addresses two outstanding needs of the FDOT. The first need is to support the FDOT's Strategic Intermodal System (SIS) initiative and their efforts to define and manage existing and proposed multimodal centers, modes (air, ...

Supporting Parents: How Six Decades of Parenting Research Can Inform Policy and Best Practice. Social Policy Report. Volume 30, Number 5

ERIC Educational Resources Information Center

Teti, Douglas M.; Cole, Pamela M.; Cabrera, Natasha; Goodman, Sherryl H.; McLoyd, Vonnie C.

2017-01-01

In this paper, we call attention to the need to expand existing efforts and to develop policies, programs, and best practices in the United States designed to support parents at risk and promote parenting competence. Despite the existence of some services offered to parents of children at risk due to developmental delay or at economic risk, the…

Continuation of research into software for space operations support, volume 1

NASA Technical Reports Server (NTRS)

Collier, Mark D.; Killough, Ronnie; Martin, Nancy L.

1990-01-01

A prototype workstation executive called the Hardware Independent Software Development Environment (HISDE) was developed. Software technologies relevant to workstation executives were researched and evaluated and HISDE was used as a test bed for prototyping efforts. New X Windows software concepts and technology were introduced into workstation executives and related applications. The four research efforts performed included: (1) Research into the usability and efficiency of Motif (an X Windows based graphic user interface) which consisted of converting the existing Athena widget based HISDE user interface to Motif demonstrating the usability of Motif and providing insight into the level of effort required to translate an application from widget to another; (2) Prototype a real time data display widget which consisted of research methods for and prototyping the selected method of displaying textual values in an efficient manner; (3) X Windows performance evaluation which consisted of a series of performance measurements which demonstrated the ability of low level X Windows to display textural information; (4) Convert the Display Manager to X Window/Motif which is the application used by NASA for data display during operational mode.

An Empirical Study of Presage Variables in the Teaching-Learning of Statistics, in the Light of Research on Competencies

ERIC Educational Resources Information Center

Rodriguez, Clemente; Gutierrez-Perez, Jose; Pozo, Teresa

2010-01-01

Introduction: This research seeks to determine the influence exercised by a set of presage and process variables (students' pre-existing opinion towards statistics, their dedication to mastery of statistics content, assessment of the teaching materials, and the teacher's effort in the teaching of statistics) in students' resolution of activities…

State of the Research and Literature Address: ACT with Children, Adolescents and Parents

ERIC Educational Resources Information Center

Murrell, Amy R.; Scherbarth, Andrew J.

2011-01-01

Acceptance and Commitment Therapy (ACT; Hayes, Strosahl, & Wilson, 1999) has been found effective in treating a wide number of psychological conditions affecting adults. To date, however, little research has been done on the use of ACT with youth and parents. Few efforts have been made at summarizing the literature that does exist. This article,…

AFGL Fiscal Year 1989. Air Force Technical Objectives Document

DTIC Science & Technology

1988-10-01

analyzing and forecasting atmospheric parameters. The critical technologies are cloud and precipitation effects, atmospheric boundary effects, climatology for...on the morphology and dynamics of auroral electron and ion precipitation using existing and future satellite data bases. The research will specify the...other ground based diagnostics. In the transport and particle precipitation dominated regions of polar cap, oval, and trough, research efforts are

Crop Characteristics Research: Growth and Reflectance Analysis

NASA Technical Reports Server (NTRS)

Badhwar, G. D. (Principal Investigator)

1985-01-01

Much of the early research in remote sensing follows along developing spectral signatures of cover types. It was found, however, that a signature from an unknown cover class could not always be matched to a catalog value of known cover class. This approach was abandoned and supervised classification schemes followed. These were not efficient and required extensive training. It was obvious that data acquired at a single time could not separate cover types. A large portion of the proposed research has concentrated on modeling the temporal behavior of agricultural crops and on removing the need for any training data in remote sensing surveys; the key to which is the solution of the so-called 'signature extension' problem. A clear need to develop spectral estimaters of crop ontogenic stages and yield has existed even though various correlations have been developed. Considerable effort in developing techniques to estimate these variables was devoted to this work. The need to accurately evaluate existing canopy reflectance model(s), improve these models, use them to understand the crop signatures, and estimate leaf area index was the third objective of the proposed work. A synopsis of this research effort is discussed.

Earth materials research: Report of a Workshop on Physics and Chemistry of Earth Materials

NASA Technical Reports Server (NTRS)

1987-01-01

The report concludes that an enhanced effort of earth materials research is necessary to advance the understanding of the processes that shape the planet. In support of such an effort, there are new classes of experiments, new levels of analytical sensitivity and precision, and new levels of theory that are now applicable in understanding the physical and chemical properties of geological materials. The application of these capabilities involves the need to upgrade and make greater use of existing facilities as well as the development of new techniques. A concomitant need is for a sample program involving their collection, synthesis, distribution, and analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This program summary describes each of the DOE's Biomass Energy System's projects funded or in existence during fiscal year 1979 and reflects their status as of September 30, 1979. The summary provides an overview of the ongoing research, development, and demonstration efforts of the preceding fiscal year as well. (DMC)

76 FR 70456 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... in developing mechanisms for reviewing and disseminating Comparative Effectiveness Research (CER) and... through its Effective Healthcare Program (EHCP). CER directly compares the benefits, potential risks, and... augment AHRQ's existing CER dissemination efforts performed by the Eisenberg Center and other initiatives...

Research Needs: Prime-Power for High Energy Space Systems.

DTIC Science & Technology

1982-06-01

nuclear sources included both developments from earlier NASA/AEC efforts, such as the present SP-100 program , and also advanced concepts in the form of...and, in some cases, set aside). major programs of applied-research and exploratory- development exist at AFWAL and at NASA labora- tories. The results...decades. In such a research program , the particular I problems of a specific device presently under development are less important than the creation of

New hypersonic facility capability at NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Haas, Jeffrey E.; Chamberlin, Roger; Dicus, John H.

1989-01-01

Four facility activities are underway at NASA Lewis Research Center to develop new hypersonic propulsion test capability. Two of these efforts consist of upgrades to existing operational facilities. The other two activities will reactivate facilities that have been in a standby condition for over 15 years. These four activities are discussed and the new test facilities NASA Lewis will have in place to support evolving high speed research programs are described.

ENERGY AND SCIENCE: Five-Year Bibliography 1990-1994

DTIC Science & Technology

1995-12-01

reviews the U.S. government’s efforts to support Venezuela’s energy sector. Sector de Energia en Venezuela: La Prodnccion Petrolera y las Condiciones... renovate existing laboratories or build new ones is often minimal. Four of the eight agencies recently started up task forces to reexamine their research...laboratory repairs. Moreover, funding to renovate existing laboratories or build new ones is often minimal. Four of the eight agencies recently started up

The distribution of biomedical research resources and international justice.

PubMed

Resnik, David B

2004-05-01

According to some estimates, less than 10% of the world's biomedical research funds are dedicated to addressing problems that are responsible for 90% of the world's burden of disease. This paper explains why this disparity exists and what should be done about it. It argues that the disparity exists because: 1) multinational pharmaceutical and biotechnology companies do not regard research and development investments on the health problems of developing nations to be economically lucrative; and 2) governmental agencies that sponsor biomedical research face little political pressure to allocate funds for the problems of developing nations. This paper argues that developed nations have an obligation to address disparities related to biomedical research funding. To facilitate this effort, developed countries should establish a trust fund dedicated to research on the health problems of developing nations similar to the Global AIDS Fund.

International Alzheimer's Disease Research Portfolio (IADRP) aims to capture global Alzheimer's disease research funding.

PubMed

Liggins, Charlene; Snyder, Heather M; Silverberg, Nina; Petanceska, Suzana; Refolo, Lorenzo M; Ryan, Laurie; Carrillo, Maria C

2014-05-01

Alzheimer's disease (AD) is a recognized international public health crisis. There is an urgent need for public and private funding agencies around the world to coordinate funding strategies and leverage existing resources to enhance and expand support of AD research. To capture and compare their existing investments in AD research and research-related resources, major funding organizations are starting to utilize the Common Alzheimer's Disease Research Ontology (CADRO) to categorize their funding information. This information is captured in the International Alzheimer's Disease Research Portfolio (IADRP) for further analysis. As of January, 2014, over fifteen organizations from the US, Canada, Europe and Australia have contributed their information. The goal of the IADRP project is to enable funding organizations to assess the changing landscape of AD research and coordinate strategies, leverage resources, and avoid duplication of effort. Copyright © 2014. Published by Elsevier Inc.

Potential reduction of non-residential solid waste in Sukomanunggal district West Surabaya

NASA Astrophysics Data System (ADS)

Warmadewanthi, I. D. A. A.; Reswari, S. A.

2018-01-01

Sukomanunggal district a development unit 8 with the designation as a regional trade and services, industrial, education, healthcare, offices, and shopping center. The development of this region will make an increasing solid waste generation, especially waste from non-residential facilities. The aims of this research to know the potential reduction of waste source. The method used is the Likert scale questionnaire to determine the knowledge, attitude, and behavior of non-residential facilities manager. Results from this research are the existing reduction of non-residential solid waste is 5.34%, potential reduction of the waste source is optimization of plastic and paper waste with the reduction rate up to 19,52%. The level of public participation existing amounted to 46.79% with a willingness to increase recycling efforts amounted to 72.87%. Efforts that can be developed to increase public awareness of 3R are providing three types of bins, modification of solid waste collection schedule according to a type of waste that has been sorted, the provision of the communal bin.

Advanced structures technology and aircraft safety

NASA Technical Reports Server (NTRS)

Mccomb, H. G., Jr.

1983-01-01

NASA research and development on advanced aeronautical structures technology related to flight safety is reviewed. The effort is categorized as research in the technology base and projects sponsored by the Aircraft Energy Efficiency (ACEE) Project Office. Base technology research includes mechanics of composite structures, crash dynamics, and landing dynamics. The ACEE projects involve development and fabrication of selected composite structural components for existing commercial transport aircraft. Technology emanating from this research is intended to result in airframe structures with improved efficiency and safety.

Implementation of an Object-Oriented Flight Simulator D.C. Electrical System on a Hypercube Architecture

DTIC Science & Technology

1991-12-01

abstract data type is, what an object-oriented design is and how to apply "software engineering" principles to the design of both of them. I owe a great... Program (ASVP), a research and development effort by two aerospace contractors to redesign and implement subsets of two existing flight simulators in...effort addresses how to implement a simulator designed using the SEI OOD Paradigm on a distributed, parallel, multiple instruction, multiple data (MIMD

Remote lift fan study program, volume 4

NASA Technical Reports Server (NTRS)

1973-01-01

A study program to select and conduct preliminary design of advanced technology lift fan systems to meet low noise goals of future V/STOL transport aircraft is discussed. This volume contains results of additional studies conducted to support the main preliminary design effort done under the Remote Lift Fan Study Program (Contract NAS3-14406) and a companion effort, the Integral Lift Fan Study (NAS3-14404). These results cover engine emission study, a review of existing engines for research aircraft application and support data for aircraft studies.

Research, public policymaking, and knowledge-translation processes: Canadian efforts to build bridges.

PubMed

Lavis, John N

2006-01-01

Public policymakers must contend with a particular set of institutional arrangements that govern what can be done to address any given issue, pressure from a variety of interest groups about what they would like to see done to address any given issue, and a range of ideas (including research evidence) about how best to address any given issue. Rarely do processes exist that can get optimally packaged high-quality and high-relevance research evidence into the hands of public policymakers when they most need it, which is often in hours and days, not months and years. In Canada, a variety of efforts have been undertaken to address the factors that have been found to increase the prospects for research use, including the production of systematic reviews that meet the shorter term (but not urgent) needs of public policymakers and encouraging partnerships between researchers and policymakers that allow for their interaction around the tasks of asking and answering relevant questions. Much less progress has been made in making available research evidence to inform the urgent needs of public policymakers and in addressing attitudinal barriers and capacity limitations. In the future, knowledge-translation processes, particularly push efforts and efforts to facilitate user pull, should be undertaken on a sufficiently large scale and with a sufficiently rigorous evaluation so that robust conclusions can be drawn about their effectiveness.

A Research Roadmap for Computation-Based Human Reliability Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boring, Ronald; Mandelli, Diego; Joe, Jeffrey

2015-08-01

The United States (U.S.) Department of Energy (DOE) is sponsoring research through the Light Water Reactor Sustainability (LWRS) program to extend the life of the currently operating fleet of commercial nuclear power plants. The Risk Informed Safety Margin Characterization (RISMC) research pathway within LWRS looks at ways to maintain and improve the safety margins of these plants. The RISMC pathway includes significant developments in the area of thermalhydraulics code modeling and the development of tools to facilitate dynamic probabilistic risk assessment (PRA). PRA is primarily concerned with the risk of hardware systems at the plant; yet, hardware reliability is oftenmore » secondary in overall risk significance to human errors that can trigger or compound undesirable events at the plant. This report highlights ongoing efforts to develop a computation-based approach to human reliability analysis (HRA). This computation-based approach differs from existing static and dynamic HRA approaches in that it: (i) interfaces with a dynamic computation engine that includes a full scope plant model, and (ii) interfaces with a PRA software toolset. The computation-based HRA approach presented in this report is called the Human Unimodels for Nuclear Technology to Enhance Reliability (HUNTER) and incorporates in a hybrid fashion elements of existing HRA methods to interface with new computational tools developed under the RISMC pathway. The goal of this research effort is to model human performance more accurately than existing approaches, thereby minimizing modeling uncertainty found in current plant risk models.« less

Sharing data is a shared responsibility: Commentary on: "The essential nature of sharing in science".

PubMed

Giffels, Joe

2010-12-01

Research data should be made readily available. A robust data-sharing plan, led by the principal investigator of the research project, requires considerable administrative and operational resources. Because external support for data sharing is minimal, principal investigators should consider engaging existing institutional information experts, such as librarians and information systems personnel, to participate in data-sharing efforts.

Predicting Citizen Satisfaction with Government Services in Belize

DTIC Science & Technology

2015-03-26

treatments are being executed on existing groups as the community population, a quasi-experimental approach using the nonequivalent control group design ... design and survey procedures before concluding with a discussion of the anticipated significance of the research . Chapter II is an article to be...York School Belize City, Belize $75,000 Experiment Design While both Hansen and this research effort answer distinctly different questions, the

Emerging inequality in effort: A longitudinal investigation of parental involvement and early elementary school-aged children's learning time in Japan.

PubMed

Matsuoka, Ryoji; Nakamuro, Makiko; Inui, Tomohiko

2015-11-01

While studies on effort (e.g., Carbonaro, 2005; Kariya, 2000, 2013) have revealed relationships among students' effort (e.g., self-reported learning time), socioeconomic status, and school-related factors (e.g., tracking) through secondary education data, whether and how the effort gap emerges and widens in the early years of compulsory education have not been researched. This study investigates the beginning of inequality in effort by using four waves (from first- to fourth-grade students) of the Longitudinal Survey of Babies in the 21st Century, collected in Japan. The results indicate that college-educated parents tend to employ parenting practices that directly and indirectly shape children's learning time; inequality in effort exists, and it becomes exacerbated partly because of parenting differences in a society with a relatively equal elementary education system. Copyright © 2015 Elsevier Inc. All rights reserved.

SWATShare- A Platform for Collaborative Hydrology Research and Education with Cyber-enabled Sharing, Running and Visualization of SWAT Models

NASA Astrophysics Data System (ADS)

Rajib, M. A.; Merwade, V.; Song, C.; Zhao, L.; Kim, I. L.; Zhe, S.

2014-12-01

Setting up of any hydrologic model requires a large amount of efforts including compilation of all the data, creation of input files, calibration and validation. Given the amount of efforts involved, it is possible that models for a watershed get created multiple times by multiple groups or organizations to accomplish different research, educational or policy goals. To reduce the duplication of efforts and enable collaboration among different groups or organizations around an already existing hydrology model, a platform is needed where anyone can search for existing models, perform simple scenario analysis and visualize model results. The creator and users of a model on such a platform can then collaborate to accomplish new research or educational objectives. From this perspective, a prototype cyber-infrastructure (CI), called SWATShare, is developed for sharing, running and visualizing Soil Water Assessment Tool (SWAT) models in an interactive GIS-enabled web environment. Users can utilize SWATShare to publish or upload their own models, search and download existing SWAT models developed by others, run simulations including calibration using high performance resources provided by XSEDE and Cloud. Besides running and sharing, SWATShare hosts a novel spatio-temporal visualization system for SWAT model outputs. In temporal scale, the system creates time-series plots for all the hydrology and water quality variables available along the reach as well as in watershed-level. In spatial scale, the system can dynamically generate sub-basin level thematic maps for any variable at any user-defined date or date range; and thereby, allowing users to run animations or download the data for subsequent analyses. In addition to research, SWATShare can also be used within a classroom setting as an educational tool for modeling and comparing the hydrologic processes under different geographic and climatic settings. SWATShare is publicly available at https://www.water-hub.org/swatshare.

Energy Options: Challenge for the Future

ERIC Educational Resources Information Center

Hammond, Allen L.

1972-01-01

Summarizes alternative technological possibilities for ensuring a supply of energy for the United States, including nuclear technology, solar energy, shale oil and coal gassification, low pollutant techniques for burning coal, and a fuel cell suitable for commercial use. Reports the extent of existing research and development efforts. (AL)

A TRAINING MODEL FOR THE JOBLESS ADULT.

ERIC Educational Resources Information Center

ULRICH, BERNARD

THE TRAINING SYSTEMS DESIGN, AN INTERDISCIPLINARY APPROACH UTILIZING KNOWLEDGE OF BEHAVIORAL SCIENCES, NEW INSTRUCTIONAL TECHNOLOGY, AND SYSTEMS DESIGN, HAS BEEN APPLIED TO DEVELOP A MODEL FOR RE-EDUCATING AND TRAINING THE AGING UNEMPLOYED. RESEARCH INTO EXISTING MDTA DEMONSTRATION PROGRAMS BY THE COOPERATIVE EFFORTS OF MCGRAW-HILL AND THE…

Cognitive Efficiency: A Conceptual and Methodological Comparison

ERIC Educational Resources Information Center

Hoffman, Bobby

2012-01-01

Cognitive efficiency (CE) is generally defined as qualitative increases in knowledge gained in relation to the time and effort invested in knowledge acquisition. Across disciplines, limited consensus exists concerning the conceptual and measurement properties of CE partly because some researchers indiscriminately use the construct of CE to…

How Effective Is Telecommuting? Assessing the Status of Our Scientific Findings.

PubMed

Allen, Tammy D; Golden, Timothy D; Shockley, Kristen M

2015-10-01

Telecommuting has become an increasingly popular work mode that has generated significant interest from scholars and practitioners alike. With recent advances in technology that enable mobile connections at ever-affordable rates, working away from the office as a telecommuter has become increasingly available to many workers around the world. Since the term telecommuting was first coined in the 1970s, scholars and practitioners have debated the merits of working away from the office, as it represents a fundamental shift in how organizations have historically done business. Complicating efforts to truly understand the implications of telecommuting have been the widely varying definitions and conceptualizations of telecommuting and the diverse fields in which research has taken place.Our objective in this article is to review existing research on telecommuting in an effort to better understand what we as a scientific community know about telecommuting and its implications. In so doing, we aim to bring to the surface some of the intricacies associated with telecommuting research so that we may shed insights into the debate regarding telecommuting's benefits and drawbacks. We attempt to sift through the divergent and at times conflicting literature to develop an overall sense of the status of our scientific findings, in an effort to identify not only what we know and what we think we know about telecommuting, but also what we must yet learn to fully understand this increasingly important work mode.After a brief review of the history of telecommuting and its prevalence, we begin by discussing the definitional challenges inherent within existing literature and offer a comprehensive definition of telecommuting rooted in existing research. Our review starts by highlighting the need to interpret existing findings with an understanding of how the extent of telecommuting practiced by participants in a study is likely to alter conclusions that may be drawn. We then review telecommuting's implications for employees' work-family issues, attitudes, and work outcomes, including job satisfaction, organizational commitment and identification, stress, performance, wages, withdrawal behaviors, and firm-level metrics. Our article continues by discussing research findings concerning salient contextual issues that might influence or alter the impact of telecommuting, including the nature of the work performed while telecommuting, interpersonal processes such as knowledge sharing and innovation, and additional considerations that include motives for telecommuting such as family responsibilities. We also cover organizational culture and support that may shape the telecommuting experience, after which we discuss the community and societal effects of telecommuting, including its effects on traffic and emissions, business continuity, and work opportunities, as well as the potential impact on societal ties. Selected examples of telecommuting legislation and policies are also provided in an effort to inform readers regarding the status of the national debate and its legislative implications. Our synthesis concludes by offering recommendations for telecommuting research and practice that aim to improve the quality of data on telecommuting as well as identify areas of research in need of development. © The Author(s) 2015.

Center for Modeling of Turbulence and Transition: Research Briefs, 1995

NASA Technical Reports Server (NTRS)

1995-01-01

This research brief contains the progress reports of the research staff of the Center for Modeling of Turbulence and Transition (CMOTT) from July 1993 to July 1995. It also constitutes a progress report to the Institute of Computational Mechanics in Propulsion located at the Ohio Aerospace Institute and the Lewis Research Center. CMOTT has been in existence for about four years. In the first three years, its main activities were to develop and validate turbulence and combustion models for propulsion systems, in an effort to remove the deficiencies of existing models. Three workshops on computational turbulence modeling were held at LeRC (1991, 1993, 1994). At present, CMOTT is integrating the CMOTT developed/improved models into CFD tools which can be used by the propulsion systems community. This activity has resulted in an increased collaboration with the Lewis CFD researchers.

Center for modeling of turbulence and transition: Research briefs, 1995

NASA Astrophysics Data System (ADS)

1995-10-01

This research brief contains the progress reports of the research staff of the Center for Modeling of Turbulence and Transition (CMOTT) from July 1993 to July 1995. It also constitutes a progress report to the Institute of Computational Mechanics in Propulsion located at the Ohio Aerospace Institute and the Lewis Research Center. CMOTT has been in existence for about four years. In the first three years, its main activities were to develop and validate turbulence and combustion models for propulsion systems, in an effort to remove the deficiencies of existing models. Three workshops on computational turbulence modeling were held at LeRC (1991, 1993, 1994). At present, CMOTT is integrating the CMOTT developed/improved models into CFD tools which can be used by the propulsion systems community. This activity has resulted in an increased collaboration with the Lewis CFD researchers.

Development of a Temperature Sensor for Jet Engine and Space Missions Environments

NASA Technical Reports Server (NTRS)

Patterson, Richard L.; Hammoud, Ahmad; Culley, Dennis E.; Elbuluk, Malik

2008-01-01

Electronic systems in aerospace and in space exploration missions are expected to encounter extreme temperatures and wide thermal swings. To address the needs for extreme temperature electronics, research efforts exist at the NASA Glenn Research Center (GRC) to develop and evaluate electronics for extreme temperature operations, and to establish their reliability under extreme temperature operation and thermal cycling; conditions that are typical of both the aerospace and space environments. These efforts are supported by the NASA Fundamental Aeronautics/Subsonic Fixed Wing Program and by the NASA Electronic Parts and Packaging (NEPP) Program. This work reports on the results obtained on the development of a temperature sensor geared for use in harsh environments.

The Healthy Aging Research Network: Modeling Collaboration for Community Impact.

PubMed

Belza, Basia; Altpeter, Mary; Smith, Matthew Lee; Ory, Marcia G

2017-03-01

As the first Centers for Disease Control and Prevention (CDC) Prevention Research Centers Program thematic network, the Healthy Aging Research Network was established to better understand the determinants of healthy aging within older adult populations, identify interventions that promote healthy aging, and assist in translating research into sustainable community-based programs throughout the nation. To achieve these goals requires concerted efforts of a collaborative network of academic, community, and public health organizational partnerships. For the 2001-2014 Prevention Research Center funding cycles, the Healthy Aging Research Network conducted prevention research and promoted the wide use of practices known to foster optimal health. Organized around components necessary for successful collaborations (i.e., governance and infrastructure, shaping focus, community involvement, and evaluation and improvement), this commentary highlights exemplars that demonstrate the Healthy Aging Research Network's unique contributions to the field. The Healthy Aging Research Network's collaboration provided a means to collectively build capacity for practice and policy, reduce fragmentation and duplication in health promotion and aging research efforts, maximize the efficient use of existing resources and generate additional resources, and ultimately, create synergies for advancing the healthy aging agenda. This collaborative model was built upon a backbone organization (coordinating center); setting of common agendas and mutually reinforcing activities; and continuous communications. Given its successes, the Healthy Aging Research Network model could be used to create new and evaluate existing thematic networks to guide the translation of research into policy and practice. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Landscape of the EU-US Research Infrastructures and actors: Moving towards international interoperability of earth system data

NASA Astrophysics Data System (ADS)

Asmi, Ari; Powers, Lindsay

2015-04-01

Research Infrastructures (RIs) are major long-term investments supporting innovative, bottom-up research activities. In the environmental research, they range from high atmosphere radars, to field observation networks and coordinated laboratory facilities. The Earth system is highly interactive and each part of the system interconnected across the spatial and disciplinary borders. However, due practical and historical reasons, the RIs are built from disciplinary points-of-view and separately in different parts of the world, with differing standards, policies, methods and research cultures. This heterogeneity provides necessary diversity to study the complex Earth system, but makes cross-disciplinary and/or global interoperability a challenge. Global actions towards better interoperability are surfacing, especially with EU and US. For example, recent mandates within the US government prioritize open data for federal agencies and federally funded science, and encourage collaboration among agencies to reduce duplication of efforts and increase efficient use of resources. There are several existing initiatives working toward these goals (e.g., COOPEUS, EarthCube, RDA, ICSU-WDS, DataOne, ESIP, USGEO, GEO). However, there is no cohesive framework to coordinate efforts among these, and other, entities. COOPEUS and EarthCube have now begun to map the landscape of interoperability efforts across earth science domains. The COOPEUS mapping effort describes the EU and US landscape of environmental research infrastructures to accomplish the following: identify gaps in services (data provision) necessary to address societal priorities; provide guidance for development of future research infrastructures; and identify opportunities for Research Infrastructures (RIs) to collaborate on issues of common interest. EarthCube mapping effort identifies opportunities to engage a broader community by identifying scientific domain organizations and entities. We present the current situation of the landscape analysis to create a sustainable effort towards removing barriers to interoperability on a global scale.

Stakeholders' engagement with Ebola therapy research in resource limited settings.

PubMed

Folayan, Morenike Oluwatoyin; Brown, Brandon; Haire, Bridget; Yakubu, Aminu; Peterson, Kristin; Tegli, Jemee

2015-06-26

The current Ebola Virus Disease (EVD) outbreak in West Africa is the largest in history. As of February 18(th) 2015, 23,258 cases of EVD have been cumulatively reported from Nigeria, Senegal, Guinea, Liberia, Mali, Sierra Leone, Spain, the United Kingdom and the United States of America resulting in more than 9,000 deaths. It is therefore exigent to develop prevention and treatment therapies for EVD. Several new EVD treatments are in clinical development at this time. Based on lessons learned, four critical processes need to be implemented before clinical trials begin. First, all global EVD research need to be coordinated to promote data sharing and synergistic overlap, while reducing unnecessary duplication of efforts. The World Health Organization is well-placed to undertake such an endeavor. Second, governments of affected nations where trials are being proposed need to lead discussions regarding immediate access to any proven medications for epidemics. Also, governments need to leverage international resources to support and expand existing national expertise to jointly conduct high-caliber clinical research; and resources must be used to enhance local technical skills and expand existing personnel. Third, ethics committees must review protocols, monitor the research process, and work closely with research scientists to insure the ethical integrity of research throughout the trials. Fourth, community advisory boards (CAB) need to be formed, linked with existing community leadership structures and organized in conjunction with trial implementation. These community structures should work together with ethics committees to facilitate the study design, informed consent process, and study implementation. We must facilitate communication and mutual understanding between trial communities and research teams, and promote positive collaborations between all stakeholders engaged in EVD research. The community engagement process for EVD research is crucial to address myths and misconceptions, and to promote study volunteers' understanding of the research details. The collaboration between all stakeholders is crucial for continued long term partnership to address EVD outbreak and none of the stakeholders should be left behind in ongoing efforts to develop EVD therapies.

Funtools: Fits Users Need Tools for Quick, Quantitative Analysis

NASA Technical Reports Server (NTRS)

Mandel, Eric; Brederkamp, Joe (Technical Monitor)

2001-01-01

The Funtools project arose out of conversations with astronomers about the decline in their software development efforts over the past decade. A stated reason for this decline is that it takes too much effort to master one of the existing FITS libraries simply in order to write a few analysis programs. This problem is exacerbated by the fact that astronomers typically develop new programs only occasionally, and the long interval between coding efforts often necessitates re-learning the FITS interfaces. We therefore set ourselves the goal of developing a minimal buy-in FITS library for researchers who are occasional (but serious) coders. In this case, "minimal buy-in" meant "easy to learn, easy to use, and easy to re-learn next month". Based on conversations with astronomers interested in writing code, we concluded that this goal could be achieved by emphasizing two essential capabilities. The first was the ability to write FITS programs without knowing much about FITS, i.e., without having to deal with the arcane rules for generating a properly formatted FITS file. The second was to support the use of already-familiar C/Unix facilities, especially C structs and Unix stdio. Taken together, these two capabilities would allow researchers to leverage their existing programming expertise while minimizing the need to learn new and complex coding rules.

Actionable Science Lessons Emerging from the Department of Interior Climate Science Center Network

NASA Astrophysics Data System (ADS)

McMahon, G.; Meadow, A. M.; Mikels-Carrasco, J.

2015-12-01

The DOI Advisory Committee on Climate Change and Natural Resource Science (ACCCNRS) has recommended that co-production of actionable science be the core programmatic focus of the Climate Science Center enterprise. Efforts by the Southeast Climate Science Center suggest that the complexity of many climate adaptation decision problems (many stakeholders that can influence implementation of a decision; the problems that can be viewed at many scales in space and time; dynamic objectives with competing values; complex, non-linear systems) complicates development of research-based information that scientists and non-scientists view as comprehensible, trustworthy, legitimate, and accurate. Going forward, organizers of actionable science efforts should consider inclusion of a broad set of stakeholders, beyond formal decisionmakers, and ensure that sufficient resources are available to explore the interests and values of this broader group. Co-produced research endeavors should foster agency and collaboration across a wide range of stakeholders. We recognize that stakeholder agency may be constrained by scientific or political power structures that limit the ability to initiate discussion, make claims, and call things into question. Co-production efforts may need to be preceded by more descriptive assessments that summarize existing climate science in ways that stakeholders can understand and link with their concerns. Such efforts can build rapport and trust among scientists and non-scientists, and may help stakeholders and scientists alike to frame adaptation decision problems amenable to a co-production effort. Finally, university and government researchers operate within an evaluation structure that rewards researcher-driven science that, at the extreme, "throws information over the fence" in the hope that information users will make better decisions. Research evaluation processes must reward more consultative, collaborative, and collegial research approaches if researchers are to widely adopt co-production methods

Critical Issues in Large-Scale Assessment: A Resource Guide.

ERIC Educational Resources Information Center

Redfield, Doris

The purpose of this document is to provide practical guidance and support for the design, development, and implementation of large-scale assessment systems that are grounded in research and best practice. Information is included about existing large-scale testing efforts, including national testing programs, state testing programs, and…

But How Do We Talk about It?: Critical Literacy Practices for Addressing Sexuality with Youth

ERIC Educational Resources Information Center

Ashcraft, Catherine

2012-01-01

To date, literacy educators receive little instruction and, indeed, little research exists on facilitating critical discussions about sexuality in classrooms. Addressing these issues with students, however, grows increasingly urgent, particularly in light of critical media literacy efforts and progressive literacy pedagogies that incorporate…

The SMART Goal Framework: Teacher Perceptions of Professional Learning and Teacher Practice

ERIC Educational Resources Information Center

Yates, Sigrid S.

2014-01-01

Most states require that schools engage in school improvement programs to meet accountability mandates which necessitates that teachers develop the skills necessary to accomplish school improvement efforts. The problem is that classroom practitioners lack the skills necessary to achieve effective school improvement. Limited research exists with…

Pilot Study of Puerto Rican Junior Colleges. Final Report.

ERIC Educational Resources Information Center

Garcia-Kuenzli, Pablo

Despite an arduous effort to cope with modern Puerto Rico's societal needs, Puerto Rican junior colleges' educational offerings are inadequate and often irrelevant. The complexity and peculiarities of the junior college system in Puerto Rico cannot be fully grasped within the existing models for educational research designed for the educational…

College Women's Rape Awareness and Use of Commonly Advocated Risk Reduction Strategies

ERIC Educational Resources Information Center

Hertzog, Jodie; Yeilding, Rosemary

2009-01-01

Despite national efforts to create awareness about acquaintance rape and substance- facilitated sexual assault on college campuses, little empirical research investigates whether college women are incorporating these messages into their social behavior. This exploratory study adds to the existing literature by investigating college women's…

Integrated reclamation: Approaching ecological function?

Treesearch

Ann L. Hild; Nancy L. Shaw; Ginger B. Paige

2009-01-01

Attempts to reclaim arid and semiarid lands have traditionally targeted plant species composition. Much research attention has been directed to seeding rates, species mixes and timing of seeding. However, in order to attain functioning systems, attention to structure and process must compliment existing efforts. We ask how to use a systems approach to enhance...

Financial Aid's Role in Meeting State College Completion Goals

ERIC Educational Resources Information Center

Hillman, Nicholas W.; Orians, Erica Lee

2013-01-01

This brief utilizes the most recent and rigorous financial aid research to inform state higher education leaders about innovative and effective financial aid practices. By simplifying aid eligibility requirements, improving the aid application process, and engaging in early awareness efforts, states could improve the effectiveness of existing aid…

Chicana/Latina "Testimonios" on Effects and Responses to Microaggressions

ERIC Educational Resources Information Center

Huber, Lindsay Perez; Cueva, Bert Maria

2012-01-01

"Testimonio" in educational research can reveal both the oppression that exists within educational institutions and the powerful efforts in which students of color engage to challenge and transform those spaces. We utilize "testimonio" as a methodological approach to understand how undocumented and U.S.-born Chicana/Latina students experience the…

Elementary/Middle School Keyboarding Strategies Guide.

ERIC Educational Resources Information Center

National Business Education Association, Reston, VA.

Developed through a cooperative effort of many teachers and researchers, this guide is intended to supplement existing elementary and middle school materials on keyboarding. The guide contains sections that are designed for stand-alone use. Topics cover a wide range of strategies, including teaching special needs students. The U.S. Postal Service…

Whiteness and absorbency of hydroentangled cotton-based nonwoven fabrics of different constituent fibers and fiber blends

USDA-ARS?s Scientific Manuscript database

This manuscript reports result of the research efforts devoted to the exploration and development of greige (non-bleached) cotton-containing nonwoven fabrics that likely could be made optimally competitive in cost, quality and performance to existing products that presently and predominantly use man...

Exploring Staff Facilitation that Supports Family Learning

ERIC Educational Resources Information Center

Pattison, Scott A.; Dierking, Lynn D.

2012-01-01

Front-line educators are arguably critical to the visitor experience at museums and science centers across the country. However, little research exists to inform staff facilitation strategies or professional development efforts. In this article, we describe the results of a qualitative study of 63 staff-family interactions in a science center,…

78 FR 26308 - Endangered and Threatened Wildlife and Plants; Proposed Threatened Status for Coral Pink Sand...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-06

... appropriate habitat is found, the area will be considered for experimental introduction. The conservation committee will increase research efforts in experimental translocations in Conservation Area B and evaluate... conduct experimental vegetation treatments within existing conservation areas to determine if this...

The Streetlight Effect in Type 1 Diabetes

PubMed Central

Battaglia, Manuela

2015-01-01

In the nearly 100 years since the discovery of therapeutic insulin, significant research efforts have been directed at finding the underlying cause of type 1 diabetes (T1D) and developing a “cure” for the disease. While progress has clearly been made toward each of these goals, neither vision has been fulfilled. With increasing pressure from both public and private funders of diabetes research, growing impatience of those with T1D at the lack of practical discoveries, increased competition for research funds, uncertainties on the reproducibility of published scientific data, and questions regarding the value of animal models, the current research environment has become extraordinarily difficult to traverse from the perspective of investigators. As a result, there is an increasing pressure toward performance of what might be considered “safe” research, where the aim is to affirm existing dogmas rather than to pioneer efforts involving unconventional thought. Psychologists refer to this practice as “observational bias” while cartoonists label the process the “streetlight effect.” In this Perspective, we consider notions in T1D research that should be subject to bold question and provide additional concepts, many somewhat orphan to research efforts, whose investigation could lead to a means for truly identifying the cause of and a cure for T1D. PMID:25805758

Power Subsystem for Extravehicular Activities for Exploration Missions

NASA Technical Reports Server (NTRS)

Manzo, Michelle

2005-01-01

The NASA Glenn Research Center has the responsibility to develop the next generation space suit power subsystem to support the Vision for Space Exploration. Various technology challenges exist in achieving extended duration missions as envisioned for future lunar and Mars mission scenarios. This paper presents an overview of ongoing development efforts undertaken at the Glenn Research Center in support of power subsystem development for future extravehicular activity systems.

Federal Plan for Cyber Security and Information Assurance Research and Development

DTIC Science & Technology

2006-04-01

Security Systems 103 varieties of the BB84 scheme have been developed, and other forms of quantum key distribution have been proposed. Rapid progress has led... key . Capability Gaps Existing quantum cryptographic protocols may also have weaknesses. Although BB84 is generally regarded as secure , researchers...complement agency-specific prioritization and R&D planning efforts in cyber security and information assurance. The Plan also describes the key Federal

Flight Testing the Rotor Systems Research Aircraft (RSRA)

NASA Technical Reports Server (NTRS)

Hall, G. W.; Merrill, R. K.

1983-01-01

In the late 1960s, efforts to advance the state-of-the-art in rotor systems technology indicated a significant gap existed between our ability to accurately predict the characteristics of a complex rotor system and the results obtained through flight verification. Even full scale wind tunnel efforts proved inaccurate because of the complex nature of a rotating, maneuvering rotor system. The key element missing, which prevented significant advances, was our inability to precisely measure the exact rotor state as a function of time and flight condition. Two Rotor Research Aircraft (RSRA) were designed as pure research aircraft and dedicated rotor test vehicles whose function is to fill the gap between theory, wind tunnel testing, and flight verification. The two aircraft, the development of the piloting techniques required to safely fly the compound helicopter, the government flight testing accomplished to date, and proposed future research programs.

A suggested outline for writing curriculum development journal articles: the IDCRD format.

PubMed

Reznich, C B; Anderson, W A

2001-01-01

During the past decade, medical school and residency faculty have been active in developing and revising curricula for medical education programs. Many of these curriculum development efforts ultimately are published in peer-reviewed professional journals as articles or abstracts. Unlike research publications, no uniform format currently exists for reporting curriculum development efforts in the peer-reviewed literature. A suggested format for organizing curriculum development manuscripts consists of the introduction, development, curriculum, results, and discussion (IDCRD). Detailed descriptions of each section are discussed herein. The IDCRD manuscript outline is intended to provide useful guidance to medical educators in publishing their curriculum development efforts. Journal editors are encouraged to recognize the importance of providing uniform descriptions of curricula so that readers can benefit from the experience of others and replicate successful curriculum efforts.

Quantum Sensing and Communications Being Developed for Nanotechnology

NASA Technical Reports Server (NTRS)

Lekki, John D.; Nguyen, Quang-Viet

2005-01-01

An interdisciplinary quantum communications and sensing research effort for application in microdevices has been underway at the NASA Glenn Research Center since 2000. Researchers in Glenn's Instrumentation and Controls, Communications Technology, and Propulsion and Turbomachinery Divisions have been working together to study and develop techniques that utilize quantum effects for sensing and communications. The emerging technology provides an innovative way to communicate faster and farther using less power and to sense, measure, and image environmental properties in ways that are not possible with existing technology.

The ethical use of existing samples for genome research.

PubMed

Bathe, Oliver F; McGuire, Amy L

2009-10-01

Modern biobanking efforts consist of prospective collections of tissues linked to clinical data for patients who have given informed consent for the research use of their specimens and data, including their DNA. In such efforts, patient autonomy and privacy are well respected because of the prospective nature of the informed consent process. However, one of the richest sources of tissue for research continues to be the millions of archived samples collected by pathology departments during normal clinical care or for research purposes without specific consent for future research or genetic analysis. Because specific consent was not obtained a priori, issues related to individual privacy and autonomy are much more complicated. A framework for accessing these existing samples and related clinical data for research is presented. Archival tissues may be accessed only when there is a reasonable likelihood of generating beneficial and scientifically valid information. To minimize risks, databases containing information related to the tissue and to clinical data should be coded, no personally identifying phenotypic information should be included, and access should be restricted to bona fide researchers for legitimate research purposes. These precautions, if implemented appropriately, should ensure that the research use of archival tissue and data are no more than minimal risk. A waiver of the requirement for informed consent would then be justified if reconsent is shown to be impracticable. A waiver of consent should not be granted, however, if there is a significant risk to privacy, if the proposed research use is inconsistent with the original consent (where there is one), or if the potential harm from a privacy breach is considerable.

Culture: The missing link in health research.

PubMed

Kagawa Singer, M; Dressler, W; George, S

2016-12-01

Culture is essential for humans to exist. Yet surprisingly little attention has been paid to identifying how culture works or developing standards to guide the application of this concept in health research. This paper describes a multidisciplinary effort to find consensus on essential elements of a definition of culture to guide researchers in studying how cultural processes influence health and health behaviors. We first highlight the lack of progress made in the health sciences to explain differences between population groups, and then identify 10 key barriers in research impeding progress in more effectively and rapidly realizing equity in health outcomes. Second, we highlight the primarily mono-cultural lens through which health behavior is currently conceptualized, third, we present a consensus definition of culture as an integrating framework, and last, we provide guidelines to more effectively operationalize the concept of culture for health research. We hope this effort will be useful to researchers, reviewers, and funders alike. Copyright © 2016 Elsevier Ltd. All rights reserved.

National Hydropower Plant Dataset, Version 1 (Update FY18Q2)

DOE Data Explorer

Samu, Nicole; Kao, Shih-Chieh; O'Connor, Patrick; Johnson, Megan; Uria-Martinez, Rocio; McManamay, Ryan

2016-09-30

The National Hydropower Plant Dataset, Version 1, Update FY18Q2, includes geospatial point-level locations and key characteristics of existing hydropower plants in the United States that are currently online. These data are a subset extracted from NHAAP’s Existing Hydropower Assets (EHA) dataset, which is a cornerstone of NHAAP’s EHA effort that has supported multiple U.S. hydropower R&D research initiatives related to market acceleration, environmental impact reduction, technology-to-market activities, and climate change impact assessment.

Resident guide to advocacy in dermatology.

PubMed

Park, Kelly K

2015-12-01

Many opportunities exist for residents to get involved in advocacy in dermatology, from national to grassroots levels. Residents also should be aware of opportunities to get involved in patient advocacy and become familiar with the myriad of patient advocacy groups that exist. These groups offer support and education for patients and initiate research efforts for specific dermatologic conditions that provide support for patients beyond what can be offered during a standard office visit. The value of resident involvement in advocacy also is discussed.

HCE Research Coordination Directorate (ReCoorD Database)

DTIC Science & Technology

2016-04-27

portfolio management is often hidden within broader mission scopes and visibility into those portfolio is often limited at best. Current specialty...specific tracking databases do not exist. Current broad-sweeping portfolio management tools do not exist (not true--define terms?). The HCE receives...requests from a variety of oversight bodies for reports on the current state of project-through- portfolio efforts. Tools such as NIH’s Reporter, while still in development, do not yet appear to meet HCE element requirements.

Exploring a taxonomy for aggression against women: can it aid conceptual clarity?

PubMed

Cook, Sarah; Parrott, Dominic

2009-01-01

The assessment of aggression against women is demanding primarily because assessment strategies do not share a common language to describe reliably the wide range of forms of aggression women experience. The lack of a common language impairs efforts to describe these experiences, understand causes and consequences of aggression against women, and develop effective intervention and prevention efforts. This review accomplishes two goals. First, it applies a theoretically and empirically based taxonomy to behaviors assessed by existing measurement instruments. Second, it evaluates whether the taxonomy provides a common language for the field. Strengths of the taxonomy include its ability to describe and categorize all forms of aggression found in existing quantitative measures. The taxonomy also classifies numerous examples of aggression discussed in the literature but notably absent from quantitative measures. Although we use existing quantitative measures as a starting place to evaluate the taxonomy, its use is not limited to quantitative methods. Implications for theory, research, and practice are discussed.

Developing a Science Commons for Geosciences

NASA Astrophysics Data System (ADS)

Lenhardt, W. C.; Lander, H.

2016-12-01

Many scientific communities, recognizing the research possibilities inherent in data sets, have created domain specific archives such as the Incorporated Research Institutions for Seismology (iris.edu) and ClinicalTrials.gov. Though this is an important step forward, most scientists, including geoscientists, also use a variety of software tools and at least some amount of computation to conduct their research. While the archives make it simpler for scientists to locate the required data, provisioning disk space, compute resources, and network bandwidth can still require significant efforts. This challenge exists despite the wealth of resources available to researchers, namely lab IT resources, institutional IT resources, national compute resources (XSEDE, OSG), private clouds, public clouds, and the development of cyberinfrastructure technologies meant to facilitate use of those resources. Further tasks include obtaining and installing required tools for analysis and visualization. If the research effort is a collaboration or involves certain types of data, then the partners may well have additional non-scientific tasks such as securing the data and developing secure sharing methods for the data. These requirements motivate our investigations into the "Science Commons". This paper will present a working definition of a science commons, compare and contrast examples of existing science commons, and describe a project based at RENCI to implement a science commons for risk analytics. We will then explore what a similar tool might look like for the geosciences.

Anatomy of an organizational change effort at the Lewis Research Center

NASA Technical Reports Server (NTRS)

Hawker, James R.; Dali, Richard S.

1988-01-01

By 1979, after a long decline following the end of the Apollo program, the Lewis Research Center found its very existence endangered because it was not doing the kind of research that could attract funding at the time. New management under Andrew J. Stofan applied a program of strategic planning, participative management, and consensus decision making. A corporate-cultural change was effected which enabled Lewis to commit itself to four fundable research and development projects. Morale-building and training programs which were essential to this change are described.

Guidance for human interface with artificial intelligence systems

NASA Technical Reports Server (NTRS)

Potter, Scott S.; Woods, David D.

1991-01-01

The beginning of a research effort to collect and integrate existing research findings about how to combine computer power and people is discussed, including problems and pitfalls as well as desirable features. The goal of the research is to develop guidance for the design of human interfaces with intelligent systems. Fault management tasks in NASA domains are the focus of the investigation. Research is being conducted to support the development of guidance for designers that will enable them to make human interface considerations into account during the creation of intelligent systems.

An overview of NASA research on positive displacement general-aviation engines

NASA Technical Reports Server (NTRS)

Kempke, E. E., Jr.

1980-01-01

The research and technology program related to improved and advanced general aviation engines is described. Current research is directed at the near-term improvement of conventional air-cooled spark-ignition piston engines and at future alternative engine systems based on all-new spark-ignition piston engines, lightweight diesels, and rotary combustion engines that show potential for meeting program goals in the midterm and long-term future. The conventional piston engine activities involve efforts on applying existing technology to improve fuel economy, investigation of key processes to permit leaner operation and reduce drag, and the development of cost effective technology to permit flight at high-altitudes where fuel economy and safety are improved. The advanced engine concepts activities include engine conceptual design studies and enabling technology efforts on the critical or key technology items.

A Comparison of Online and Traditional Chemistry Lecture and Lab

ERIC Educational Resources Information Center

Faulconer, E. K.; Griffith, J. C.; Wood, B. L.; Acharyya, S.; Roberts, D. L.

2018-01-01

While the equivalence between online and traditional classrooms has been well researched, very little effort has been expended to do such comparisons for college level introductory chemistry. The existing literature has only one study that investigated chemistry lectures at an entire course level as opposed to particular course components such as…

Implementing Intensive Vocabulary Instruction for Students at Risk for Reading Disability

ERIC Educational Resources Information Center

Pullen, Paige C.; Tuckwiller, Elizabeth D.; Ashworth, Kristen; Lovelace, Shelly P.; Cash, Deanna

2011-01-01

Concerns regarding literacy levels in the United States are long standing. Debates have existed for decades regarding the most effective ways to teach reading, especially the polarizing dilemma of how much to focus on decoding versus code-emphasis and whole language instruction. Fortunately, as a result of concentrated research efforts and…

Examining the Factors Resulting in Faculty Unionization at Three Ohio Community Colleges

ERIC Educational Resources Information Center

Stilson-Hart, Amy

2009-01-01

Unionization efforts on community college campuses have increased fivefold over the past decade, this research addressed issues relating to increased levels of faculty unionization on community college campuses in Ohio. The purpose of this quantitative study was to examine and describe what, if any, relationships exist among faculty union…

School Districts and Student Achievement

ERIC Educational Resources Information Center

Chingos, Matthew M.; Whitehurst, Grover J.; Gallaher, Michael R.

2015-01-01

School districts are a focus of education reform efforts in the United States, but there is very little existing research about how important they are to student achievement. We fill this gap in the literature using 10 years of student-level, statewide data on fourth- and fifth-grade students in Florida and North Carolina. A variance decomposition…

Project Report, Part One, Final Report for Phase I, Rural Shared Services.

ERIC Educational Resources Information Center

Northern Montana Coll., Havre.

In an attempt to identify, synthesize, and evaluate shared services research and development efforts conducted throughout the nation, and bring those results together in a single report, Part One of a four-part report defines rural shared services and the organizational patterns under which shared service activity exists, describes the activities…

Experiences of Instructors in Online Learning Environments: Identifying and Regulating Emotions

ERIC Educational Resources Information Center

Regan, Kelley; Evmenova, Anna; Baker, Pam; Jerome, Marci Kinas; Spencer, Vicky; Lawson, Holly; Werner, Terry

2012-01-01

In an effort to expand existing research on the barriers of instructors experience in online learning environments (OLEs), a qualitative study was conducted at a large mid-Atlantic university. Six instructors teaching in different OLE formats (e.g., asynchronous, hybrid, and synchronous via videoconferencing) participated in two focus groups in…

Implementation of a Curriculum-Integrated Computer Game for Introducing Scientific Argumentation

ERIC Educational Resources Information Center

Wallon, Robert C.; Jasti, Chandana; Lauren, Hillary Z. G.; Hug, Barbara

2018-01-01

Argumentation has been emphasized in recent US science education reform efforts (NGSS Lead States 2013; NRC 2012), and while existing studies have investigated approaches to introducing and supporting argumentation (e.g., McNeill and Krajcik in "Journal of Research in Science Teaching," 45(1), 53-78, 2008; Kang et al. in "Science…

Sex, Productivity and Reward in Academe.

ERIC Educational Resources Information Center

Harlan, Anne; And Others

This study attempts to utilize more refined measures of rewards and productivity than have been employed in past research in an effort to determine whether differences in rewards offered to men and women exist, and if they do, whether such differences can be explained in terms of differing rates of productivity. A 10-page questionnaire was…

Unifying theory for terrestrial research infrastructures

NASA Astrophysics Data System (ADS)

Mirtl, Michael

2016-04-01

The presentation will elaborate on basic steps needed for building a common theoretical base between Research Infrastructures focusing on terrestrial ecosystems. This theoretical base is needed for developing a better cooperation and integrating in the near future. An overview of different theories will be given and ways to a unifying approach explored. In the second step more practical implications of a theory-guided integration will be developed alongside the following guiding questions: • How do the existing and planned European environmental RIs map on a possible unifying theory on terrestrial ecosystems (covered structures and functions, scale; overlaps and gaps) • Can a unifying theory improve the consistent definition of RÍs scientific scope and focal science questions? • How could a division of tasks between RIs be organized in order to minimize parallel efforts? • Where concretely do existing and planned European environmental RIs need to interact to respond to overarching questions (top down component)? • What practical fora and mechanisms (across RIs) would be needed to bridge the gap between PI driven (bottom up) efforts and the centralistic RI design and operations?

Use of antarctic analogs to support the space exploration initiative

NASA Technical Reports Server (NTRS)

Wharton, Robert; Roberts, Barney; Chiang, Erick; Lynch, John; Roberts, Carol; Buoni, Corinne; Andersen, Dale

1990-01-01

This report has discussed the Space Exploration Initiative (SEI) and the U.S. Antarctic Program (USAP) in the context of assessing the potential rationale and strategy for conducting a cooperative NASA/NSF (National Science Foundation) effort. Specifically, such an effort would address shared research and data on living and conducting scientific research in isolated, confined, hostile, and remote environments. A review of the respective goals and requirements of NASA and the NSF indicates that numerous opportunities exist to mutually benefit from sharing relevant technologies, data, and systems. Two major conclusions can be drawn: (1) The technologies, experience, and capabilities existing and developing in the aerospace community would enhance scientific research capabilities and the efficiency and effectiveness of operations in Antarctica. The transfer and application of critical technologies (e.g., power, waste management, life support) and collaboration on crew research needs (e.g., human behavior and medical support needs) would streamline the USAP operations and provide the scientific community with advancements in facilities and tools for Antarctic research. (2) Antarctica is the most appropriate earth analog for the environments of the the Moon and Mars. Using Antarctica in this way would contribute substantially to near- and long-term needs and plans for the SEI. Antarctica is one of the few ground-based analogs that would permit comprehensive and integrated studies of three areas deemed critical to productive and safe operations on the Moon and Mars: human health and productivity; innovative scientific research techniques; and reliable, efficient technologies and facilities.

Use of antarctic analogs to support the space exploration initiative

NASA Astrophysics Data System (ADS)

Wharton, Robert; Roberts, Barney; Chiang, Erick; Lynch, John; Roberts, Carol; Buoni, Corinne; Andersen, Dale

1990-12-01

This report has discussed the Space Exploration Initiative (SEI) and the U.S. Antarctic Program (USAP) in the context of assessing the potential rationale and strategy for conducting a cooperative NASA/NSF (National Science Foundation) effort. Specifically, such an effort would address shared research and data on living and conducting scientific research in isolated, confined, hostile, and remote environments. A review of the respective goals and requirements of NASA and the NSF indicates that numerous opportunities exist to mutually benefit from sharing relevant technologies, data, and systems. Two major conclusions can be drawn: (1) The technologies, experience, and capabilities existing and developing in the aerospace community would enhance scientific research capabilities and the efficiency and effectiveness of operations in Antarctica. The transfer and application of critical technologies (e.g., power, waste management, life support) and collaboration on crew research needs (e.g., human behavior and medical support needs) would streamline the USAP operations and provide the scientific community with advancements in facilities and tools for Antarctic research. (2) Antarctica is the most appropriate earth analog for the environments of the the Moon and Mars. Using Antarctica in this way would contribute substantially to near- and long-term needs and plans for the SEI. Antarctica is one of the few ground-based analogs that would permit comprehensive and integrated studies of three areas deemed critical to productive and safe operations on the Moon and Mars: human health and productivity; innovative scientific research techniques; and reliable, efficient technologies and facilities.

Collaborative translational research leading to multicenter clinical trials in Duchenne muscular dystrophy: the Cooperative International Neuromuscular Research Group (CINRG).

PubMed

Escolar, Diana M; Henricson, Erik K; Pasquali, Livia; Gorni, Ksenija; Hoffman, Eric P

2002-10-01

Progress in the development of rationally based therapies for Duchenne muscular dystrophy has been accelerated by encouraging multidisciplinary, multi-institutional collaboration between basic science and clinical investigators in the Cooperative International Research Group. We combined existing research efforts in pathophysiology by a gene expression profiling laboratory with the efforts of animal facilities capable of conducting high-throughput drug screening and toxicity testing to identify safe and effective drug compounds that target different parts of the pathophysiologic cascade in a genome-wide drug discovery approach. Simultaneously, we developed a clinical trial coordinating center and an international network of collaborating physicians and clinics where those drugs could be tested in large-scale clinical trials. We hope that by bringing together investigators at these facilities and providing the infrastructure to support their research, we can rapidly move new bench discoveries through animal model screening and into therapeutic testing in humans in a safe, timely and cost-effective setting.

Integrating qualitative research methods into care improvement efforts within a learning health system: addressing antibiotic overuse.

PubMed

Munoz-Plaza, Corrine E; Parry, Carla; Hahn, Erin E; Tang, Tania; Nguyen, Huong Q; Gould, Michael K; Kanter, Michael H; Sharp, Adam L

2016-08-15

Despite reports advocating for integration of research into healthcare delivery, scant literature exists describing how this can be accomplished. Examples highlighting application of qualitative research methods embedded into a healthcare system are particularly needed. This article describes the process and value of embedding qualitative research as the second phase of an explanatory, sequential, mixed methods study to improve antibiotic stewardship for acute sinusitis. Purposive sampling of providers for in-depth interviews improved understanding of unwarranted antibiotic prescribing and elicited stakeholder recommendations for improvement. Qualitative data collection, transcription and constant comparative analyses occurred iteratively. Emerging themes and sub-themes identified primary drivers of unwarranted antibiotic prescribing patterns and recommendations for improving practice. These findings informed the design of a health system intervention to improve antibiotic stewardship for acute sinusitis. Core components of the intervention are also described. Qualitative research can be effectively applied in learning healthcare systems to elucidate quantitative results and inform improvement efforts.

The VIDA Framework as an Education Tool: Leveraging Volcanology Data for Educational Purposes

NASA Astrophysics Data System (ADS)

Faied, D.; Sanchez, A.

2009-04-01

The VIDA Framework as an Education Tool: Leveraging Volcanology Data for Educational Purposes Dohy Faied, Aurora Sanchez (on behalf of SSP08 VAPOR Project Team) While numerous global initiatives exist to address the potential hazards posed by volcanic eruption events and assess impacts from a civil security viewpoint, there does not yet exist a single, unified, international system of early warning and hazard tracking for eruptions. Numerous gaps exist in the risk reduction cycle, from data collection, to data processing, and finally dissemination of salient information to relevant parties. As part of the 2008 International Space University's Space Studies Program, a detailed gap analysis of the state of volcano disaster risk reduction was undertaken, and this paper presents the principal results. This gap analysis considered current sensor technologies, data processing algorithms, and utilization of data products by various international organizations. Recommendations for strategies to minimize or eliminate certain gaps are also provided. In the effort to address the gaps, a framework evolved at system level. This framework, known as VIDA, is a tool to develop user requirements for civil security in hazardous contexts, and a candidate system concept for a detailed design phase. While the basic intention of VIDA is to support disaster risk reduction efforts, there are several methods of leveraging raw science data to support education across a wide demographic. Basic geophysical data could be used to educate school children about the characteristics of volcanoes, satellite mappings could support informed growth and development of societies in at-risk areas, and raw sensor data could contribute to a wide range of university-level research projects. Satellite maps, basic geophysical data, and raw sensor data are combined and accessible in a way that allows the relationships between these data types to be explored and used in a training environment. Such a resource naturally lends itself to research efforts in the subject but also research in operational tools, system architecture, and human/machine interaction in civil protection or emergency scenarios.

Analysis of Existing Privacy-Preserving Protocols in Domain Name System

NASA Astrophysics Data System (ADS)

Zhao, Fangming; Hori, Yoshiaki; Sakurai, Kouichi

In a society preoccupied with gradual erosion of electronic privacy, loss of privacy in the current Domain Name System is an important issue worth considering. In this paper, we first review the DNS and some security & privacy threats to make average users begin to concern about the significance of privacy preservation in DNS protocols. Then, by an careful survey of four noise query generation based existing privacy protection approaches, we analyze some benefits and limitations of these proposals in terms of both related performance evaluation results and theoretic proofs. Finally, we point out some problems that still exist for research community's continuing efforts in the future.

Research priorities to reduce the global burden of dementia by 2025.

PubMed

Shah, Hiral; Albanese, Emiliano; Duggan, Cynthia; Rudan, Igor; Langa, Kenneth M; Carrillo, Maria C; Chan, Kit Yee; Joanette, Yves; Prince, Martin; Rossor, Martin; Saxena, Shekhar; Snyder, Heather M; Sperling, Reisa; Varghese, Mathew; Wang, Huali; Wortmann, Marc; Dua, Tarun

2016-11-01

At the First WHO Ministerial Conference on Global Action Against Dementia in March, 2015, 160 delegates, including representatives from 80 WHO Member States and four UN agencies, agreed on a call for action to reduce the global burden of dementia by fostering a collective effort to advance research. To drive this effort, we completed a globally representative research prioritisation exercise using an adapted version of the Child Health and Nutrition Research Initiative method. We elicited 863 research questions from 201 participants and consolidated these questions into 59 thematic research avenues, which were scored anonymously by 162 researchers and stakeholders from 39 countries according to five criteria. Six of the top ten research priorities were focused on prevention, identification, and reduction of dementia risk, and on delivery and quality of care for people with dementia and their carers. Other priorities related to diagnosis, biomarkers, treatment development, basic research into disease mechanisms, and public awareness and understanding of dementia. Research priorities identified by this systematic international process should be mapped onto the global dementia research landscape to identify crucial gaps and inform and motivate policy makers, funders, and researchers to support and conduct research to reduce the global burden of dementia. Efforts are needed by all stakeholders, including WHO, WHO Member States, and civil society, to continuously monitor research investments and progress, through international platforms such as a Global Dementia Observatory. With established research priorities, an opportunity now exists to translate the call for action into a global dementia action plan to reduce the global burden of dementia. Copyright © 2016 Elsevier Ltd. All rights reserved.

Non-US electrodynamic launchers research and development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parker, J.V.; Batteh, J.H.; Greig, J.R.

Electrodynamic launcher research and development work of scientists outside the United States is analyzed and assessed by six internationally recognized US experts in the field of electromagnetic and electrothermal launchers. The assessment covers five broad technology areas: (1) Experimental railguns; (2) Railgun theory and design; (3) Induction launchers; (4) Electrothermal guns; (5) Energy storage and power supplies. The overall conclusion is that non-US work on electrodynamic launchers is maturing rapidly after a relatively late start in many countries. No foreign program challenges the US efforts in scope, but it is evident that the United States may be surpassed in somemore » technologies within the next few years. Until recently, published Russian work focused on hypervelocity for research purposes. Within the last two years, large facilities have been described where military-oriented development has been underway since the mid-1980s. Financial support for these large facilities appears to have collapsed, leaving no effective effort to develop practical launchers for military or civilian applications. Electrodynamic launcher research in Europe is making rapid progress by focusing on a single application, tactical launchers for the military. Four major laboratories, in Britain, France, Germany, and the Netherlands, are working on this problem. Though narrower in scope than the US effort, the European work enjoys a continuity of support that has accelerated its progress. The next decade will see the deployment of electrodynamic launcher technology, probably in the form of an electrothermal-chemical upgrade for an existing gun system. The time scale for deployment of electromagnetic launchers is entirely dependent on the level of research-and-development effort. If resources remain limited, the advantage will lie with cooperative efforts that have reasonably stable funding such as the present French-German program.« less

The Amphibian Research and Monitoring Initiative (ARMI): 5-year report

USGS Publications Warehouse

Muths, Erin; Gallant, Alisa L.; Campbell Grant, Evan H.; Battaglin, William A.; Green, David E.; Staiger, Jennifer S.; Walls, Susan C.; Gunzburger, Margaret S.; Kearney, Rick F.

2006-01-01

This report is a 5-year retrospective of the structure, methodology, progress, and contributions to the broader scientific community that have resulted from this national USGS program. We evaluate ARMI’s success to date, with regard to the challenges faced by the program and the strengths that have emerged. We chart objectives for the next 5 years that build on current accomplishments, highlight areas meriting further research, and direct efforts to overcome existing weaknesses.

Optical and acoustic metamaterials: superlens, negative refractive index and invisibility cloak

NASA Astrophysics Data System (ADS)

Wong, Zi Jing; Wang, Yuan; O'Brien, Kevin; Rho, Junsuk; Yin, Xiaobo; Zhang, Shuang; Fang, Nicholas; Yen, Ta-Jen; Zhang, Xiang

2017-08-01

Metamaterials are artificially engineered materials that exhibit novel properties beyond natural materials. By carefully designing the subwavelength unit cell structures, unique effective properties that do not exist in nature can be attained. Our metamaterial research aims to develop new subwavelength structures with unique physics and experimentally demonstrate unprecedented properties. Here we review our research efforts in optical and acoustic metamaterials in the past 15 years which may lead to exciting applications in communications, sensing and imaging.

Funding global emergency medicine research-from seed grants to NIH support.

PubMed

Hansoti, Bhakti; Levine, Adam; Ganti, Latha; Oteng, Rockefeller; DesRosiers, Taylor; Modi, Payal; Brown, Jeremy

2016-12-01

Funding for global health has grown significantly over the past two decades. Numerous funding opportunities for international development and research work exist; however, they can be difficult to navigate. The 2013 Academic Emergency Medicine consensus conference on global health and emergency care identified the need to strengthen global emergency care research funding, solidify existing funding streams, and expand funding sources. This piece focuses on the various federal funding opportunities available to support emergency physicians conducting international research from seed funding to large institutional grants. In particular, we focus on the application and review processes for the Fulbright and Fogarty programs, National Institutes of Health (NIH) Career development awards, and the Medical Education Partnership Initiative (MEPI), including tips and pathways through each application process. Lastly, the paper provides an index that may be used as a guide in determining whether the amount of funding provided by a grant is worth the effort in applying.

Measuring public health practice and outcomes in chronic disease: a call for coordination.

PubMed

Porterfield, Deborah S; Rogers, Todd; Glasgow, LaShawn M; Beitsch, Leslie M

2015-04-01

A strategic opportunity exists to coordinate public health systems and services researchers' efforts to develop local health department service delivery measures and the efforts of divisions within the Centers for Disease Control and Prevention's National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) to establish outcome indicators for public health practice in chronic disease. Several sets of outcome indicators developed by divisions within NCCDPHP and intended for use by state programs can be tailored to assess outcomes of interventions within smaller geographic areas or intervention settings. Coordination of measurement efforts could potentially allow information to flow from the local to the state to the federal level, enhancing program planning, accountability, and even subsequent funding for public health practice.

A National Virtual Specimen Database for Early Cancer Detection

NASA Technical Reports Server (NTRS)

Crichton, Daniel; Kincaid, Heather; Kelly, Sean; Thornquist, Mark; Johnsey, Donald; Winget, Marcy

2003-01-01

Access to biospecimens is essential for enabling cancer biomarker discovery. The National Cancer Institute's (NCI) Early Detection Research Network (EDRN) comprises and integrates a large number of laboratories into a network in order to establish a collaborative scientific environment to discover and validate disease markers. The diversity of both the institutions and the collaborative focus has created the need for establishing cross-disciplinary teams focused on integrating expertise in biomedical research, computational and biostatistics, and computer science. Given the collaborative design of the network, the EDRN needed an informatics infrastructure. The Fred Hutchinson Cancer Research Center, the National Cancer Institute,and NASA's Jet Propulsion Laboratory (JPL) teamed up to build an informatics infrastructure creating a collaborative, science-driven research environment despite the geographic and morphology differences of the information systems that existed within the diverse network. EDRN investigators identified the need to share biospecimen data captured across the country managed in disparate databases. As a result, the informatics team initiated an effort to create a virtual tissue database whereby scientists could search and locate details about specimens located at collaborating laboratories. Each database, however, was locally implemented and integrated into collection processes and methods unique to each institution. This meant that efforts to integrate databases needed to be done in a manner that did not require redesign or re-implementation of existing system

Use and misuse of research in books on sex trafficking: implications for interdisciplinary researchers, practitioners, and advocates.

PubMed

Fedina, Lisa

2015-04-01

Recent articles have raised important questions about the validity of prevalence data on human trafficking, exposing flawed methodologies behind frequently cited statistics. While considerable evidence points to the fact that human trafficking does exist in the United States and abroad, many sources of literature continue to cite flawed data and some misuse research in ways that seemingly inflate the problem, which can have serious implications for anti-trafficking efforts, including victim services and anti-trafficking legislation and policy. This systematic review reports on the prevalence data used in 42 recently published books on sex trafficking to determine the extent to which published books rely on data estimates and just how they use or misuse existing data. The findings from this review reveal that the vast majority of published books do rely on existing data that were not rigorously produced and therefore may be misleading or at minimum, inaccurate. Implications for practice, research, and policy are discussed, as well as recommendations for future prevalence studies on human trafficking. © The Author(s) 2014.

Cryogenic Wind Tunnel Models. Design and Fabrication

NASA Technical Reports Server (NTRS)

Young, C. P., Jr. (Compiler); Gloss, B. B. (Compiler)

1983-01-01

The principal motivating factor was the National Transonic Facility (NTF). Since the NTF can achieve significantly higher Reynolds numbers at transonic speeds than other wind tunnels in the world, and will therefore occupy a unique position among ground test facilities, every effort is being made to ensure that model design and fabrication technology exists to allow researchers to take advantage of this high Reynolds number capability. Since a great deal of experience in designing and fabricating cryogenic wind tunnel models does not exist, and since the experience that does exist is scattered over a number of organizations, there is a need to bring existing experience in these areas together and share it among all interested parties. Representatives from government, the airframe industry, and universities are included.

ECR plasma thruster research - Preliminary theory and experiments

NASA Technical Reports Server (NTRS)

Sercel, Joel C.; Fitzgerald, Dennis J.

1989-01-01

A preliminary theory of the operation of the electron-cyclotron-resonance (ECR) plasma thruster is described along with an outline of recent experiments. This work is presented to communicate the status of an ongoing research effort directed at developing a unified theory to quantitatively describe the operation of the ECR plasma thruster. The theory is presented as a set of nonlinear ordinary differential equations and boundary conditions which describe the plasma density, velocity, and electron temperature. Diagnostic tools developed to measure plasma conditions in the existing research device are described.

Guidelines for the air-sea interaction special study: An element of the NASA climate research program, JPL/SIO workshop report

NASA Technical Reports Server (NTRS)

1980-01-01

A program in the area of air sea interactions is introduced. A space capability is discussed for global observations of climate parameters which will contribute to the understanding of the processes which influence climate and its predictability. The following recommendations are some of the suggestions made for air sea interaction studies: (1) a major effort needs to be devoted to the preparation of space based climatic data sets; (2) NASA should create a group or center for climatic data analysis due to the substantial long term effort that is needed in research and development; (3) funding for the analyses of existing data sets should be augmented and continued beyond the termination of present programs; (4) NASA should fund studies in universities, research institutions and governments' centers; and (5) the planning for an air sea interaction mission should be an early task.

Development of a Production Ready Automated Wire Delivery System

NASA Technical Reports Server (NTRS)

1997-01-01

The current development effort is a Phase 3 research study entitled "A Production Ready Automated Wire Delivery System", contract number NAS8-39933, awarded to Nichols Research Corporation (NRC). The goals of this research study were to production harden the existing Automated Wire Delivery (AWDS) motion and sensor hardware and test the modified AWDS in a range of welding applications. In addition, the prototype AWDS controller would be moved to the VME bus platform by designing, fabricating and testing a single board VME bus AWDS controller. This effort was to provide an AWDS that could transition from the laboratory environment to production operations. The project was performed in two development steps. Step 1 modified and tested an improved MWG. Step 2 developed and tested the AWDS single board VME bus controller. Step 3 installed the Wire Pilot in a Weld Controller with the imbedded VME bus controller.

A Review of Water Reclamation Research in China Urban Landscape Design and Planning Practice

NASA Astrophysics Data System (ADS)

Gan, Wei; Zeng, Tianran

2018-04-01

With the continuously growing demand for better living environment, more and more attention and efforts have been paid to the improvement of urban landscape. However, the expansion of green area and water features are at the cost of high consumption of water resources, which has become prominent problems in cities that suffer from water shortage. At the same time, with the water shortage and water environment deterioration problems that shared globally, water conservation has become an inevitable choice to achieve sustainable social development. Urban landscape is not simply a consuming body of water resources, but also are of water-saving potential and able to perform the function of water storage. Thus, recycling the limited water resources becomes a challenge for every landscape designer. This paper is intended to overview the existing effort of reclaimed water recycle research in China landscape designing fields, and raise recommendations for future research and development.

Scientific collaboration and team science: a social network analysis of the centers for population health and health disparities.

PubMed

Okamoto, Janet

2015-03-01

The past decade has seen dramatic shifts in the way that scientific research is conducted as networks, consortia, and large research centers are funded as transdisciplinary, team-based enterprises to tackle complex scientific questions. Key investigators (N = 167) involved in ten health disparities research centers completed a baseline social network and collaboration readiness survey. Collaborative ties existed primarily between investigators from the same center, with just 7 % of ties occurring across different centers. Grants and work groups were the most common types of ties between investigators, with shared presentations the most common tie across different centers. Transdisciplinary research orientation was associated with network position and reciprocity. Center directors/leaders were significantly more likely to form ties with investigators in other roles, such as statisticians and trainees. Understanding research collaboration networks can help to more effectively design and manage future team-based research, as well as pinpoint potential issues and continuous evaluation of existing efforts.

Analyzing ex-ante agroforestry adoption decisions with attribute based choice experiments

Treesearch

Evan Mercer; Ann Snook

2004-01-01

Although many cases of successful agroforestry extension efforts exist (for examples, see Chapter 2), all too often attempts to promote agroforestry have resulted in low adoption rates, with farmers reluctant to adopt new or improved agroforestry systems or abandoning agroforestry shortly after establishment. As a result, the recent increase in research on the adoption...

Professional Counseling in South Africa: A Landscape under Construction

ERIC Educational Resources Information Center

Maree, Jacobus G.; van der Westhuizen, Carol N.

2011-01-01

The focus of this article is on the history, status, and trends of the counseling profession in South Africa and on the similarities with the development of the counseling profession in the United States. A need exists for South African professional counselors to refocus their research efforts to reflect the realities of the 21st century and link…

Causal Attribution: A New Scale Developed to Minimize Existing Methodological Problems.

ERIC Educational Resources Information Center

Bull, Kay Sather; Feuquay, Jeffrey P.

In order to facilitate research on the construct of causal attribution, this paper details developmental procedures used to minimize previous deficiencies and proposes a new scale. The first version of the scale was in ipsative form and provided two basic sets of indices: (1) ability, effort, luck, and task difficulty indices in success and…

Biology Teachers' Perceptions of Subject Matter Structure and Its Relationship to Classroom Practice.

ERIC Educational Resources Information Center

Gess-Newsome, Julie; Lederman, Norman G.

Current reform efforts in the teaching of high school biology demonstrate the need for a synthetic treatment of prominent concepts. There exists insufficient research that delineates the global content understandings--in this paper designated subject matter structures (SMS)--of biology teachers; or that assesses whether these SMS do, in fact,…

Fostering Third-Grade Students' Use of Scientific Models with the Water Cycle: Elementary Teachers' Conceptions and Practices

ERIC Educational Resources Information Center

Vo, Tina; Forbes, Cory T.; Zangori, Laura; Schwarz, Christina V.

2015-01-01

Elementary teachers play a crucial role in supporting and scaffolding students' model-based reasoning about natural phenomena, particularly complex systems such as the water cycle. However, little research exists to inform efforts in supporting elementary teachers' learning to foster model-centered, science learning environments. To address this…

I Would Have Had More Success If…: Student Reflections on Their Performance in Online and Blended Courses

ERIC Educational Resources Information Center

Lewis, G. Sherrie

2010-01-01

Anecdotal research is a common phenomenon in the study of distance education. In an effort to review some of the factors that affect student satisfaction, an existing instrument was used to gauge learner perceptions of online interaction/communication, learning and performance, collaboration, hardware and software issues and the quality of…

Anti-Drug Abuse Strategy Report. State of New York. 1993 Update.

ERIC Educational Resources Information Center

New York Governor's Office, Albany. Statewide Anti-Drug Abuse Council.

Research shows a clear link between drug and alcohol use and crime and violence. This report describes progress made in 1993 as a result of New York State's anti-drug abuse agenda and priorities for 1994. Efforts exist in three complementary areas: prevention (preventing people from being involved in substance abuse); treatment (treating those who…

The Family and Federal Drug Abuse Policies--Programs: Toward Making the Invisible Family Visible.

ERIC Educational Resources Information Center

Clayton, Richard R.

1979-01-01

Notes why the family is not considered in drug policy and programing and asserts that existing conditions demand conscious consideration of the family in efforts of federal drug agencies. Data show changing parameters of drug use-abuse. A research and prevention agenda that integrates the family is presented. (Author/BEF)

A method for improved visual landscape compatibility of mobile home park

Treesearch

Daniel R. Jones

1979-01-01

This paper is a description of a research effort directed to improving the visual image of mobile home parks in the landscape. The study is an application of existing methodologies for measuring scenic quality and visual landscape compatibility to an unsolved problem. The paper summarizes two major areas of investigation: regional location factors based on visual...

Spatial patterns of longleaf pine (Pinus palustris) seedling eastablishment on the croatan national forest, North Carolina

Treesearch

Chadwick R. Avery; Susan Cohen; Kathleen C. Parker; John S. Kush

2004-01-01

Ecological research aimed at determining optimal conditions for longleaf pine regeneration has become increasingly important in efforts @ restore the longleaf pine ecosystem. Numerous authors have concluded that a negative relationship exists between the occurrence of seedlings and the occurrence of mature trees; however, observed field conditions in several North...

Usability of a Web-Based School Experience System: Opinions of IT Teachers and Teacher Candidates

ERIC Educational Resources Information Center

Genç, Zülfü

2015-01-01

With advances in information and communication technologies, the classical nature of educational institutions has changed. One innovative effort within teacher training is the Web-Based School Experience System (WBSES) developed by the researcher. In this study, the usability of an existing WBSES is evaluated from both teachers' (n = 13) and…

Strategic Class Roster Creation in Elementary Schools: Indicative of Student Reading Growth or a Waste of Time?

ERIC Educational Resources Information Center

Henderson, John Michael

2011-01-01

One managerial leadership activity school leaders control and organize, either by overseeing or successfully delegating, is the creation of class rosters. The targeted purpose of this research is to determine whether a measurable value exists in spending the time and efforts to strategically "create" elementary school classes while considering key…

Strategic Class Roster Creation in Elementary Schools: Indicative of Student Reading Growth or a Waste of Time?

ERIC Educational Resources Information Center

Henderson, John Michael

2011-01-01

One managerial leadership activity school leaders control and organize, either by overseeing or successfully delegating, is the creation of class rosters. The targeted purpose of this research is to determine whether a measurable value exists in spending the time and efforts to strategically "create" elementary school classes while…

An IRB Transformation: Increasing Quality and Efficiency Using Existing Resources

ERIC Educational Resources Information Center

Andrews, Joseph E., Jr.; Moore, J. Brian; Means, Paula; Weinberg, Richard

2012-01-01

In an effort to increase review-quality and efficiency, research administration at Wake Forest School of Medicine initiated a change in the operational structure of the Institutional Review Board (IRB) via a reconfiguring of the boards and rescheduling of the convened meetings. The number of IRB Panels was doubled and each panel/board began…

Accelerated Learning Options: Moving the Needle on Access and Success. A Study of State and Institutional Policies and Practices

ERIC Educational Resources Information Center

Western Interstate Commission for Higher Education, 2006

2006-01-01

This document was designed to inform members of the policy, education, and research communities about existing state and institutional policies and practices associated with four accelerated learning programs: Advanced Placement (AP), dual/concurrent enrollment, the International Baccalaureate (IB) Diploma Program, and Tech-Prep. This effort was…

Initial Efforts to Coordinate Appreciative Inquiry: Facilitators' Experiences and Perceptions

ERIC Educational Resources Information Center

Breslow, Ken; Crowell, Lyn; Francis, Lee; Gordon, Stephen P.

2015-01-01

Appreciative inquiry (AI) is an alternative approach to action research that moves participants beyond problem solving and builds on existing strengths as the participants co-construct a positive vision of the future and move toward that vision through collaborative inquiry. Ph.D. students enrolled in a doctoral seminar on AI (who also are…

STEM Integration in K-12 Education: Status, Prospects, and an Agenda for Research

ERIC Educational Resources Information Center

Honey, Margaret; Pearson, Greg; Schweingruber, Heidi

2014-01-01

"STEM Integration in K-12 Education" examines current efforts to connect the STEM disciplines in K-12 education. This report identifies and characterizes existing approaches to integrated STEM education, both in formal and after- and out-of-school settings. The report reviews the evidence for the impact of integrated approaches on…

Time allocation and cultural complexity: leisure time use across twelve cultures

Treesearch

Garry Chick; Sharon Xiangyou Shen

2008-01-01

This study is part of an effort to understand the effect of cultural evolution on leisure time through comparing time use across 12 cultures. We used an existing dataset initially collected by researchers affiliated with the UCLA Time Allocation Project (1987-1997), which contains behavioral data coded with standard methods from twelve native lowland Amazonian...

Measuring Institutional Effectiveness of California Community Colleges through Existing Governance Structures and External Funding Efforts

ERIC Educational Resources Information Center

Jameson-Meledy, Kathryn

2013-01-01

The purpose of this research was to compare the differing structures of governance within the California Community College (CCC) system in relation to resource development and grant management. This is to explain how governance may impact the effectiveness of institutions to strengthen services to students with funding resources secured through…

The application of remote sensing techniques to inter and intra urban analysis

NASA Technical Reports Server (NTRS)

Horton, F. E.

1972-01-01

This is an effort to assess the applicability of air and spaceborne photography toward providing data inputs to urban and regional planning, management, and research. Through evaluation of remote sensing inputs to urban change detection systems, analyzing an effort to replicate an existing urban land use data file using remotely sensed data, estimating population and dwelling units from imagery, and by identifying and evaluating a system of urban places ultilizing space photography, it was determined that remote sensing can provide data concerning land use, changes in commercial structure, data for transportation planning, housing quality, residential dynamics, and population density.

Mentoring Interdisciplinary Undergraduate Students via a Team Effort

PubMed Central

Karsai, Istvan; Knisley, Jeff; Knisley, Debra; Yampolsky, Lev; Godbole, Anant

2011-01-01

We describe how a team approach that we developed as a mentoring strategy can be used to recruit, advance, and guide students to be more interested in the interdisciplinary field of mathematical biology, and lead to success in undergraduate research in this field. Students are introduced to research in their first semester via lab rotations. Their participation in the research of four faculty members—two from biology and two from mathematics—gives them a first-hand overview of research in quantitative biology and also some initial experience in research itself. However, one of the primary goals of the lab rotation experience is that of developing teams of students and faculty that combine mathematics and statistics with biology and the life sciences, teams that subsequently mentor undergraduate research in genuine interdisciplinary environments. Thus, the team concept serves not only as a means of establishing interdisciplinary research, but also as a means of incorporating new students into existing research efforts that will then track those students into meaningful research of their own. We report how the team concept is used to support undergraduate research in mathematical biology and what types of team-building strategies have worked for us. PMID:21885821

PCTFPeval: a web tool for benchmarking newly developed algorithms for predicting cooperative transcription factor pairs in yeast.

PubMed

Lai, Fu-Jou; Chang, Hong-Tsun; Wu, Wei-Sheng

2015-01-01

Computational identification of cooperative transcription factor (TF) pairs helps understand the combinatorial regulation of gene expression in eukaryotic cells. Many advanced algorithms have been proposed to predict cooperative TF pairs in yeast. However, it is still difficult to conduct a comprehensive and objective performance comparison of different algorithms because of lacking sufficient performance indices and adequate overall performance scores. To solve this problem, in our previous study (published in BMC Systems Biology 2014), we adopted/proposed eight performance indices and designed two overall performance scores to compare the performance of 14 existing algorithms for predicting cooperative TF pairs in yeast. Most importantly, our performance comparison framework can be applied to comprehensively and objectively evaluate the performance of a newly developed algorithm. However, to use our framework, researchers have to put a lot of effort to construct it first. To save researchers time and effort, here we develop a web tool to implement our performance comparison framework, featuring fast data processing, a comprehensive performance comparison and an easy-to-use web interface. The developed tool is called PCTFPeval (Predicted Cooperative TF Pair evaluator), written in PHP and Python programming languages. The friendly web interface allows users to input a list of predicted cooperative TF pairs from their algorithm and select (i) the compared algorithms among the 15 existing algorithms, (ii) the performance indices among the eight existing indices, and (iii) the overall performance scores from two possible choices. The comprehensive performance comparison results are then generated in tens of seconds and shown as both bar charts and tables. The original comparison results of each compared algorithm and each selected performance index can be downloaded as text files for further analyses. Allowing users to select eight existing performance indices and 15 existing algorithms for comparison, our web tool benefits researchers who are eager to comprehensively and objectively evaluate the performance of their newly developed algorithm. Thus, our tool greatly expedites the progress in the research of computational identification of cooperative TF pairs.

PCTFPeval: a web tool for benchmarking newly developed algorithms for predicting cooperative transcription factor pairs in yeast

PubMed Central

2015-01-01

Background Computational identification of cooperative transcription factor (TF) pairs helps understand the combinatorial regulation of gene expression in eukaryotic cells. Many advanced algorithms have been proposed to predict cooperative TF pairs in yeast. However, it is still difficult to conduct a comprehensive and objective performance comparison of different algorithms because of lacking sufficient performance indices and adequate overall performance scores. To solve this problem, in our previous study (published in BMC Systems Biology 2014), we adopted/proposed eight performance indices and designed two overall performance scores to compare the performance of 14 existing algorithms for predicting cooperative TF pairs in yeast. Most importantly, our performance comparison framework can be applied to comprehensively and objectively evaluate the performance of a newly developed algorithm. However, to use our framework, researchers have to put a lot of effort to construct it first. To save researchers time and effort, here we develop a web tool to implement our performance comparison framework, featuring fast data processing, a comprehensive performance comparison and an easy-to-use web interface. Results The developed tool is called PCTFPeval (Predicted Cooperative TF Pair evaluator), written in PHP and Python programming languages. The friendly web interface allows users to input a list of predicted cooperative TF pairs from their algorithm and select (i) the compared algorithms among the 15 existing algorithms, (ii) the performance indices among the eight existing indices, and (iii) the overall performance scores from two possible choices. The comprehensive performance comparison results are then generated in tens of seconds and shown as both bar charts and tables. The original comparison results of each compared algorithm and each selected performance index can be downloaded as text files for further analyses. Conclusions Allowing users to select eight existing performance indices and 15 existing algorithms for comparison, our web tool benefits researchers who are eager to comprehensively and objectively evaluate the performance of their newly developed algorithm. Thus, our tool greatly expedites the progress in the research of computational identification of cooperative TF pairs. PMID:26677932

BLSS, a European approach to CELSS

NASA Technical Reports Server (NTRS)

Skoog, A. I.

1986-01-01

Several studies have revealed the benefits of a biological life support system (BLSS) in space stations. Problem areas requiring experimental and analytical investigations necessary for the development of BLSS have been identified. The nature of these problems allows for the classification into near-term (prepilot) and long-term (pilot) studies, and into terrestrial and space research programmes. The knowledge of planned European and U.S. space experiments allows for a coordination with existing Spacelab and Shuttle programmes to avoid duplication of research efforts. The Japanese also plan biological experiments on Spacelab in 1988. Coordinating efforts should provide answers to certain BLSS relevant questions. Major areas which need immediate attention are: micorgravity effects; cosmic radiation effects; use of PAR-radiation and high energy particle radiation protection; and monitoring and control (including sensor technology).

Meta-Reasoning: Monitoring and Control of Thinking and Reasoning.

PubMed

Ackerman, Rakefet; Thompson, Valerie A

2017-08-01

Meta-Reasoning refers to the processes that monitor the progress of our reasoning and problem-solving activities and regulate the time and effort devoted to them. Monitoring processes are usually experienced as feelings of certainty or uncertainty about how well a process has, or will, unfold. These feelings are based on heuristic cues, which are not necessarily reliable. Nevertheless, we rely on these feelings of (un)certainty to regulate our mental effort. Most metacognitive research has focused on memorization and knowledge retrieval, with little attention paid to more complex processes, such as reasoning and problem solving. In that context, we recently developed a Meta-Reasoning framework, used here to review existing findings, consider their consequences, and frame questions for future research. Copyright © 2017 Elsevier Ltd. All rights reserved.

Modeling nanomaterial environmental fate in aquatic systems.

PubMed

Dale, Amy L; Casman, Elizabeth A; Lowry, Gregory V; Lead, Jamie R; Viparelli, Enrica; Baalousha, Mohammed

2015-03-03

Mathematical models improve our fundamental understanding of the environmental behavior, fate, and transport of engineered nanomaterials (NMs, chemical substances or materials roughly 1-100 nm in size) and facilitate risk assessment and management activities. Although today's large-scale environmental fate models for NMs are a considerable improvement over early efforts, a gap still remains between the experimental research performed to date on the environmental fate of NMs and its incorporation into models. This article provides an introduction to the current state of the science in modeling the fate and behavior of NMs in aquatic environments. We address the strengths and weaknesses of existing fate models, identify the challenges facing researchers in developing and validating these models, and offer a perspective on how these challenges can be addressed through the combined efforts of modelers and experimentalists.

Research progress on organic-inorganic halide perovskite materials and solar cells

NASA Astrophysics Data System (ADS)

Ono, Luis K.; Qi, Yabing

2018-03-01

Owing to the intensive research efforts across the world since 2009, perovskite solar cell power conversion efficiencies (PCEs) are now comparable or even better than several other photovoltaic (PV) technologies. In this topical review article, we review recent progress in the field of organic-inorganic halide perovskite materials and solar cells. We associate these achievements with the fundamental knowledge gained in the perovskite research. The major recent advances in the fundamental perovskite material and solar cell research are highlighted, including the current efforts in visualizing the dynamical processes (in operando) taking place within a perovskite solar cell under operating conditions. We also discuss the existing technological challenges. Based on a survey of recently published works, we point out that to move the perovskite PV technology forward towards the next step of commercialization, what perovskite PV technology need the most in the coming next few years is not only further PCE enhancements, but also up-scaling, stability, and lead-toxicity.

The post-genomic era of biological network alignment.

PubMed

Faisal, Fazle E; Meng, Lei; Crawford, Joseph; Milenković, Tijana

2015-12-01

Biological network alignment aims to find regions of topological and functional (dis)similarities between molecular networks of different species. Then, network alignment can guide the transfer of biological knowledge from well-studied model species to less well-studied species between conserved (aligned) network regions, thus complementing valuable insights that have already been provided by genomic sequence alignment. Here, we review computational challenges behind the network alignment problem, existing approaches for solving the problem, ways of evaluating their alignment quality, and the approaches' biomedical applications. We discuss recent innovative efforts of improving the existing view of network alignment. We conclude with open research questions in comparative biological network research that could further our understanding of principles of life, evolution, disease, and therapeutics.

Reforming STEM Undergraduate Education: What's a Faculty Member to Do?

NASA Astrophysics Data System (ADS)

Fairweather, J.

2011-12-01

Efforts to improve undergraduate STEM education lie at the forefront of many national educational policies. The recent National Academies of Science study of discipline-based educational research (DBER)is typical of such efforts. Most of the initiatives to improve student learning in STEM focus on the the student or the instructor in the classroom (Austin, 2011). This focus is consistent with the work by Seymour & Hewitt (1997), which found that poor teaching in STEM adversely affects learning and retention in the major. Professional development efforts focus on helping the individual STEM faculty member to figure out what to do to improve student learning. Substantial research (Austin, 2011) shows that the origin of many learning problems lies beyond the control of the instructor or the individual classroom. In these circumstances what is a STEM faculty member to do? This paper explores answers to this question. The first step is to define the nature of the problem. Is it related to classroom teaching and learning such as knowledge, skills, and interest in the major? If so then what environmental factors affect strategic alternatives, including type of course, instructor characteristics, and prior teaching experience (Fairweather & Rhoads, 1995)? Does good disciplinary-based research on the learning problem exist? If so then how can the research results be translated into practice? If not then does good research from other disciplines exist? If relevant evidenced-based research does not exist at all then how can STEM instructors learn to evaluate key learning outcomes and find ways to ameliorate problems? Despite appearances not all STEM teaching and learning problems are classroom-based. Some problems derive from curricula, others from faculty work-related issues such as rewards and work load. Any classroom reform effort must reflect accurately the system in which the teaching and learning take place. Understanding these systemic interactions improves the ability of likelihood that STEM faculty members' efforts to improve instruction in the classroom will be effective and enduring (Fisher, Fairweather, & Amey, 2003). In the presentation I discuss a program to incorporate computational competencies in the classroom and curricula. I use this example to help individual STEM instructors understand how to think about improving what goes on in their classroom while at the same time doing so in a way that increases the likelihood that the reform will work and endure. I discuss the importance of building networks among like-minded colleagues within and across institutions as a critical element in successful reform. References Austin, A. (2011). Promoting evidence based change in undergraduate science education. Washington, DC: National Academies of Science. Fairweather, J., and Rhoads, R. (1995). Teaching and the faculty role: Enhancing the commitment to instruction in American Colleges and Universities. Educational Evaluation and Policy Analysis 17: 179-194. Fisher, D., Fairweather, J., & Amey. M. (2003). Systemic reform in undergraduate engineering education: The role of collective responsibility. International Journal of Engineering Education 19: 768-776. Seymour, E. & Hewitt, N. M. (1997). Talking about leaving: Why undergraduates leave the sciences. Boulder, CO: Westview Press.

Science on a Shoestring: Building Nursing Knowledge With Limited Funding.

PubMed

Conn, Vicki S; Topp, Robert; Dunn, Susan L; Hopp, Lisa; Jadack, Rosemary; Jansen, Debra A; Jefferson, Urmeka T; Moch, Susan Diemert

2015-10-01

Building the science for nursing practice has never been more important. However, shrunken federal and state research budgets mean that investigators must find alternative sources of financial support and develop projects that are less costly to carry out. New investigators often build beginning programs of research with limited funding. This article provides an overview of some cost-effective research approaches and gives suggestions for finding other sources of funding. Examples of more cost-effective research approaches include adding complementary questions to existing funded research projects; conducting primary analysis of electronic patient records and social media content; conducting secondary analysis of data from completed studies; reviewing and synthesizing previously completed research; implementing community-based participatory research; participating in collaborative research efforts such as inter-campus team research, practice-based research networks (PBRNs), and involving undergraduate and doctoral students in research efforts. Instead of relying on funding from the National Institutes of Health (NIH) and other government agencies, nurse researchers may be able to find support for research from local sources such as businesses, organizations, or clinical agencies. Investigators will increasingly have to rely on these and other creative approaches to fund and implement their research programs if granting agency budgets do not significantly expand. © The Author(s) 2015.

Big and disparate data: considerations for pediatric consortia.

PubMed

Stingone, Jeanette A; Mervish, Nancy; Kovatch, Patricia; McGuinness, Deborah L; Gennings, Chris; Teitelbaum, Susan L

2017-04-01

Increasingly, there is a need for examining exposure disease associations in large, diverse datasets to understand the complex determinants of pediatric disease and disability. Recognizing that children's health research consortia will be important sources of big data, it is crucial for the pediatric research community to be knowledgeable about the challenges and opportunities that they will face. The present review will provide examples of existing children's health consortia, highlight recent pooled analyses conducted by children's health research consortia, address common challenges of pooled analyses, and provide recommendations to advance collective research efforts in pediatric research. Formal consortia and other collective-science initiatives are increasingly being created to share individual data from a set of relevant epidemiological studies to address a common research topic under the concept that the joint effort of many individual groups can accomplish far more than working alone. There are practical challenges to the participation of investigators within consortia that need to be addressed in order for them to work. Researchers who access consortia with data centers will be able to go far beyond their initial hypotheses and potentially accomplish research that was previously thought infeasible or too costly.

People Awakening: Collaborative Research to Develop Cultural Strategies for Prevention in Community Intervention

PubMed Central

Allen, James; Mohatt, Gerald V.; Beehler, Sarah; Rowe, Hillary L.

2014-01-01

The consequences of alcohol use disorder (AUD) and suicide create immense health disparities among Alaska Native people. The People Awakening project is a long-term collaboration between Alaska Native (AN) communities and university researchers seeking to foster health equity through development of positive solutions to these disparities. These efforts initiated a research relationship that identified individual, family, and community protective factors from AUD and suicide. AN co-researchers next expressed interest in translating these findings into intervention. This led to development of a strengths-based community intervention that is the focus of the special issue. The intervention builds these protective factors to prevent AUD and suicide risk within AN youth, and their families and communities. This review provides a critical examination of existing literature and a brief history of work leading to the intervention research. These work efforts portray a shared commitment of university researchers and community members to function as co-researchers, and to conduct research in accord with local Yup’ik cultural values. This imperative allowed the team to navigate several tensions we locate in a convergence of historical and contemporary ecological contextual factors inherent in AN tribal communities with countervailing constraints imposed by Western science. PMID:24903819

Challenges of Interdisciplinary Research: Reconciling Qualitative and Quantitative Methods for Understanding Human-Landscape Systems

NASA Astrophysics Data System (ADS)

Lach, Denise

2014-01-01

While interdisciplinary research is increasingly practiced as a way to transcend the limitations of individual disciplines, our concepts, and methods are primarily rooted in the disciplines that shape the way we think about the world and how we conduct research. While natural and social scientists may share a general understanding of how science is conducted, disciplinary differences in methodologies quickly emerge during interdisciplinary research efforts. This paper briefly introduces and reviews different philosophical underpinnings of quantitative and qualitative methodological approaches and introduces the idea that a pragmatic, realistic approach may allow natural and social scientists to work together productively. While realism assumes that there is a reality that exists independently of our perceptions, the work of scientists is to explore the mechanisms by which actions cause meaningful outcomes and the conditions under which the mechanisms can act. Our task as interdisciplinary researchers is to use the insights of our disciplines in the context of the problem to co-produce an explanation for the variables of interest. Research on qualities necessary for successful interdisciplinary researchers is also discussed along with recent efforts by funding agencies and academia to increase capacities for interdisciplinary research.

Challenges of interdisciplinary research: reconciling qualitative and quantitative methods for understanding human-landscape systems.

PubMed

Lach, Denise

2014-01-01

While interdisciplinary research is increasingly practiced as a way to transcend the limitations of individual disciplines, our concepts, and methods are primarily rooted in the disciplines that shape the way we think about the world and how we conduct research. While natural and social scientists may share a general understanding of how science is conducted, disciplinary differences in methodologies quickly emerge during interdisciplinary research efforts. This paper briefly introduces and reviews different philosophical underpinnings of quantitative and qualitative methodological approaches and introduces the idea that a pragmatic, realistic approach may allow natural and social scientists to work together productively. While realism assumes that there is a reality that exists independently of our perceptions, the work of scientists is to explore the mechanisms by which actions cause meaningful outcomes and the conditions under which the mechanisms can act. Our task as interdisciplinary researchers is to use the insights of our disciplines in the context of the problem to co-produce an explanation for the variables of interest. Research on qualities necessary for successful interdisciplinary researchers is also discussed along with recent efforts by funding agencies and academia to increase capacities for interdisciplinary research.

The Austin High School Girls' Band of Chicago, Illinois: 1925-1956

ERIC Educational Resources Information Center

Hash, Phillip M.

2018-01-01

The purpose of this study was to examine the history of the Austin High School (AHS) Girls' Band (AHSGB) of Chicago, Illinois, which existed from 1925 to 1956. This research focused on the band's (a) organization and leadership, (b) activities within the school and community, (c) relationship to the AHS Boys Band, and (d) efforts to challenge and…

Informing rangeland stewardship with research: lessons learned from Yolo County, California

Treesearch

Vance Russell; Chris Rose; Miles DaPrato

2008-01-01

Approximately 70 percent of the contiguous United States is in private lands with half of this total in row crop or rangelands. Audubon California’s Landowner Stewardship Program engages with farmers and ranchers on conservation and restoration projects in a manner compatible with existing agricultural operations. To assess the success of these efforts, Audubon,...

Implementation of the fire and fire surrogate study— a national research effort to evaluate the consequences of fuel reduction treatments

Treesearch

Andrew Youngblood; Kerry L. Metlen; Eric E. Knapp; Kenneth W. Outcalt; Scott L. Stephens; Thomas A. Waldrop; Daniel Yaussy

2005-01-01

Many fire-dependent forests today are denser, contain fewer large trees, have higher fuel loads, and greater fuel continuity than occurred under historical fire regimes. These conditions increase the probability of unnaturally severe wildfires. Silviculturists are increasingly being asked to design fuel reduction treatments to help protect existing and future forest...

Air Force Research Laboratory Technology Milestones 2010

DTIC Science & Technology

2010-01-01

these self - healing , mixed-signal integrated circuits, or HEALIC, adjust to existing conditions in order to maintain the desired level of...functionality. As part of aiding the DARPA effort to realize this self - healing capability, sensors scientists managed the development of a wideband, 6-18 GHz...technology, with the subsequent demonstration activity presenting the integrated designs containing this self - healing circuitry. The newly-concept

Research in Accrediting Efforts (Project REA). An Assessment on the Awarding of Academic Credit for CETA Activities in Illinois. Case Studies.

ERIC Educational Resources Information Center

Stoyanoff, Karen, Comp.; Klehm, Jeanette, Comp.

Summaries are presented of 15 case studies conducted at Illinois Comprehensive Employment and Training Act (CETA) regions to determine the kind of credentialing mechanisms that exist for awarding academic credit or some other record of achievement to those eligible participants who complete CETA training programs. Introductory material describes…

Risk factors for asthma and timing of exposure among first generation Arab immigrants: a pilot effort to elucidate the role of exposure to risk factors over multiple life stages

EPA Science Inventory

Considerable controversy exists over the role of aero-allergens in asthma etiology. Some studies show increased risk with microbe and allergen exposure, while others show decreased risk. These discrepancies may be explained by timing of exposure. Previous research suggests that e...

Educational Justice for Undocumented Students: How School Counselors Encourage Student Persistence in Schools

ERIC Educational Resources Information Center

Crawford, Emily R.; Valle, Fernando

2016-01-01

School counselors are critical intermediaries in K-12 schools who can help students from undocumented immigrant families persist in school. Yet, a dearth of research exists about their advocacy work, or the range of efforts they make to support unauthorized youth. This paper asks, (1) what challenges do counselors face and strive to overcome to…

Talk to the people.

PubMed

Matfield, Mark

2002-03-01

Recent opinion surveys suggest that the majority of the public is willing to accept the use of animals in research if high standards of welfare and effective regulation are in place. The public appears unaware that such standards have existed for some time. The scientific community should now re-focus its communication efforts to include the ethics and animal welfare aspects of this issue.

Constructing Scientific Applications from Heterogeneous Resources

NASA Technical Reports Server (NTRS)

Schichting, Richard D.

1995-01-01

A new model for high-performance scientific applications in which such applications are implemented as heterogeneous distributed programs or, equivalently, meta-computations, is investigated. The specific focus of this grant was a collaborative effort with researchers at NASA and the University of Toledo to test and improve Schooner, a software interconnection system, and to explore the benefits of increased user interaction with existing scientific applications.

A Phenomenological Study on the Lived Experience of First and Second Year Teachers in Standards-Based Grading Districts

ERIC Educational Resources Information Center

Battistone, William A., Jr.

2017-01-01

Problem: There is an existing cycle of questionable grading practices at the K-12 level. As a result, districts continue to search for innovative methods of evaluating and reporting student progress. One result of this effort has been the adoption of a standards-based grading approach. Research concerning standards-based grading implementation has…

Moderate Resolution Imaging Spectrometer (MODIS) design evolution and associated development and verification of data product efforts

NASA Technical Reports Server (NTRS)

Salomonson, Vincent V.

1991-01-01

The Moderate Resolution Imaging Spectrometer (MODIS) is a key observing facility to be flown on the Earth Observing System (EOS). The facility is composed of two instruments called MODIS-N (nadir) and MODIS-T (tilt). The MODIS-N is being built under contract to NASA by the Santa Barbara Research Center. The MODIS-T is being fabricated by the Engineering Directorate at the Goddard Space Flight Center. The MODIS Science Team has defined nearly 40 biogeophysical data products for studies of the ocean and land surface and properties of the atmosphere including clouds that can be expected to be produced from the MODIS instruments shortly after the launch of EOS. The ocean, land, atmosphere, and calibration groups of the MODIS Science Team are now proceeding to plan and implement the operations and facilities involving the analysis of data from existing spaceborne, airborne, and in-situ sensors required to develop and validate the algorithms that will produce the geophysical data products. These algorithm development and validation efforts will be accomplished wherever possible within the context of existing or planned national and international experiments or programs such as those in the World Climate Research Program.

Relationships among factors affecting advanced practice registered nurses' job satisfaction and intent to leave: A systematic review.

PubMed

Han, Robin M; Carter, Patricia; Champion, Jane Dimmitt

2018-02-01

This systematic review explores relationships between advanced practice registered nurses' (APRN) job satisfaction and intent to leave. There exists a dearth of APRN providers compared with the ever-growing need for their services. Furthermore, the organizational costs associated with the APRN turnover are extremely high. It, therefore, behooves practice administrators to understand what factors most contribute to APRN job satisfaction and retention. A search of research databases CINAHL, PubMed, and PsycINFO, using keywords "Advanced Practice Registered Nurse," "job satisfaction," "intent to leave," "anticipated turnover," and "Nurse Practitioner" to yield articles included in this review. The strength of existing evidence for this topic is weak. Studies have found that extrinsic factors, such as administrative support and salary, significantly contribute to job dissatisfaction, whereas intrinsic factors, such as autonomy and finding work meaningful, most significantly contribute to job satisfaction. Additional research is needed to better understand the factors relating to APRN job satisfaction and dissatisfaction, and how those factors influence practitioners' intent to leave. Efforts to improve APRN job satisfaction will have positive implications for provider retention, practices, and patients. Administrators should consider the job satisfaction factors identified herein when implementing practice improvement and retention efforts.

Management Matters: A Leverage Point for Health Systems Strengthening in Global Health

PubMed Central

Bradley, Elizabeth H.; Taylor, Lauren A.; Cuellar, Carlos J.

2015-01-01

Despite a renewed focus in the field of global health on strengthening health systems, inadequate attention has been directed to a key ingredient of high-performing health systems: management. We aimed to develop the argument that management – defined here as the process of achieving predetermined objectives through human, financial, and technical resources – is a cross-cutting function necessary for success in all World Health Organization (WHO) building blocks of health systems strengthening. Management within health systems is particularly critical in low-income settings where the efficient use of scarce resources is paramount to attaining health goals. More generally, investments in management capacity may be viewed as a key leverage point in grand strategy, as strong management enables the achievement of large ends with limited means. We also sought to delineate a set of core competencies and identify key roles to be targeted for management capacity building efforts. Several effective examples of management interventions have been described in the research literature. Together, the existing evidence underscores the importance of country ownership of management capacity building efforts, which often challenge the status quo and thus need country leadership to sustain despite inevitable friction. The literature also recognizes that management capacity efforts, as a key ingredient of effective systems change, take time to embed, as new protocols and ways of working become habitual and integrated as standard operating procedures. Despite these challenges, the field of health management as part of global health system strengthening efforts holds promise as a fundamental leverage point for achieving health system performance goals with existing human, technical, and financial resources. The evidence base consistently supports the role of management in performance improvement but would benefit from additional research with improved methodological rigor and longer-time horizon investigations. Meanwhile, greater emphasis on management as a critical element of global health efforts may open new and sustainable avenues for advancing health systems performance. PMID:26188805

Management Matters: A Leverage Point for Health Systems Strengthening in Global Health.

PubMed

Bradley, Elizabeth H; Taylor, Lauren A; Cuellar, Carlos J

2015-05-20

Despite a renewed focus in the field of global health on strengthening health systems, inadequate attention has been directed to a key ingredient of high-performing health systems: management. We aimed to develop the argument that management - defined here as the process of achieving predetermined objectives through human, financial, and technical resources - is a cross-cutting function necessary for success in all World Health Organization (WHO) building blocks of health systems strengthening. Management within health systems is particularly critical in low-income settings where the efficient use of scarce resources is paramount to attaining health goals. More generally, investments in management capacity may be viewed as a key leverage point in grand strategy, as strong management enables the achievement of large ends with limited means. We also sought to delineate a set of core competencies and identify key roles to be targeted for management capacity building efforts. Several effective examples of management interventions have been described in the research literature. Together, the existing evidence underscores the importance of country ownership of management capacity building efforts, which often challenge the status quo and thus need country leadership to sustain despite inevitable friction. The literature also recognizes that management capacity efforts, as a key ingredient of effective systems change, take time to embed, as new protocols and ways of working become habitual and integrated as standard operating procedures. Despite these challenges, the field of health management as part of global health system strengthening efforts holds promise as a fundamental leverage point for achieving health system performance goals with existing human, technical, and financial resources. The evidence base consistently supports the role of management in performance improvement but would benefit from additional research with improved methodological rigor and longer-time horizon investigations. Meanwhile, greater emphasis on management as a critical element of global health efforts may open new and sustainable avenues for advancing health systems performance. © 2015 by Kerman University of Medical Sciences.

Improved NDI techniques for aircraft inspections

NASA Astrophysics Data System (ADS)

Hagemaier, Donald J.; Wilson, Dwight

1996-11-01

Through the use of an 'integrated product team' approach and new inspection techniques incorporating the latest in imaging capabilities and automation, the costs of some man- power intensive tasks can now be drastically reduced. Also, through the use of advanced eddy current techniques, the detectable size of cracks under flush-head fasteners can be reduced while maintaining a reliable inspection. Early in this decade, the FAA Technical Center and NASA LaRC formulated an aging aircraft research plan. The unique aspect about the research is that it is driven by the aircraft manufacturers and airlines in order to center only on those areas in which help is needed and to keep it focused. Once developed, the manufacturer works with the FAA Validation Center at Sandia National Labs., the airline, and the researcher to transfer technology to the field. This article describes the evaluation and results obtained using eddy current technology to determine the minimum detectable crack size under installed flush-head fasteners. Secondly, it describes the integrated efforts of engineers at McDonnell Douglas Aerospace and Northwest Airlines in the successful application of MAUS eddy current C-scanning of the DC-10 circumferential and axial crown splices. The eddy current C-scanning greatly reduced the man-hour effort required for the existing radiographic inspection. Thirdly, it describes the use of a novel ultrasonic technique coupled to a scanner and graphics for the detection and quantification of corrosion thinning and stress corrosion cracking of the DC-9 lower wing tee cap. This successful effort resulted from a rather large integrated task team. It also results in a vast man-hour savings over the existing internal visual inspection.

Direct Current as an Integrating Platform for ZNE Buildings with EVs and Storage: DC Direct Systems – A Bridge to a Low Carbon Future?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Karl; Vossos, Vagelis; Kloss, Margarita

2016-09-01

Cost effective zero net energy (ZNE) schemes exist for many types of residential and commercial buildings. Yet, today’s alternating current (AC) based ZNE designs may be as much as 10% to 20% less efficient, more costly, and more complicated than a design based on direct current (DC) technologies. An increasing number of research organizations and manufacturers are just starting the process of developing products and conducting research and development (R&D) efforts. These early R&D efforts indicate that the use of DC technologies may deliver many energy and non-energy benefits relative to AC-based typologies. DC ZNE schemes may provide for anmore » ideal integrating platform for natively DC-based onsite generation, storage, electric vehicle (EV) charging and end-use loads. Emerging empirical data suggest that DC end-use appliances are more efficient, simpler, more durable, and lower cost. DC technologies appear to provide ratepayers a lower cost pathway to achieve resilient ZNE buildings, and simultaneously yield a plethora of benefits. This paper draws from the current research effort entitled "Direct Current as an Integrating and Enabling Platform," co-led by the Lawrence Berkeley National Laboratory (LBNL), the California Institute for Energy and the Environment (CIEE), the Electric Power Research Institute (EPRI) and funded under the California Energy Commission’s Energy Program Investment Charge (CEC EPIC). The first phase of this EPIC research is focused on assembling and summarizing known global performance information on DC and DC-AC hybrid end-use appliances and power systems. This paper summarizes the information and insights gained from this research effort.« less

Design and implementation of a prototype data system for earth radiation budget, cloud, aerosol, and chemistry data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baum, B.A.; Barkstrom, B.R.

1993-04-01

The Earth Observing System (EOS) will collect data from a large number of satellite-borne instruments, beginning later in this decade, to make data accessible to the scientific community, NASA will build an EOS Data and Information System (EOSDIS). As an initial effort to accelerate the development of EOSDIS and to gain experience with such an information system, NASA and other agencies are working on a prototype system called Version O (VO). This effort will provide improved access to pre-EOS earth science data throughout the early EOSDIS period. Based on recommendations from the EOSDIS Science Advisory Panel, EOSDIS will have severalmore » distributed active archive centers (DAACs). Each DAAC will specialize in particular data sets. This paper describes work at the NASA Langley Research Center's (LaRC) DAAC. The Version 0 Langley DAAC began archiving and distributing existing data sets pertaining to the earth's radiation budget, clouds, aerosols, and tropospheric chemistry in late 1992. The primary goals of the LaRC VO effort are the following: (1) Enhance scientific use of existing data; (2) Develop institutional expertise in maintaining and distributing data; (3) Use institutional capability for processing data from previous missions such as the Earth Radiation Budget Experiment and the Stratospheric Aerosol and Gas Experiment to prepare for processing future EOS satellite data; (4) Encourage cooperative interagency and international involvement with data sets and research; and (5) Incorporate technological hardware and software advances quickly.« less

National Science Foundation-sponsored workshop report. Draft plan for soybean genomics.

PubMed

Stacey, Gary; Vodkin, Lila; Parrott, Wayne A; Shoemaker, Randy C

2004-05-01

Recent efforts to coordinate and define a research strategy for soybean (Glycine max) genomics began with the establishment of a Soybean Genetics Executive Committee, which will serve as a communication focal point between the soybean research community and granting agencies. Secondly, a workshop was held to define a strategy to incorporate existing tools into a framework for advancing soybean genomics research. This workshop identified and ranked research priorities essential to making more informed decisions as to how to proceed with large scale sequencing and other genomics efforts. Most critical among these was the need to finalize a physical map and to obtain a better understanding of genome microstructure. Addressing these research needs will require pilot work on new technologies to demonstrate an ability to discriminate between recently duplicated regions in the soybean genome and pilot projects to analyze an adequate amount of random genome sequence to identify and catalog common repeats. The development of additional markers, reverse genetics tools, and bioinformatics is also necessary. Successful implementation of these goals will require close coordination among various working groups.

Implications of prioritizing HIV cure: new momentum to overcome old challenges in HIV.

PubMed

Tucker, Joseph D; Gilbertson, Adam; Lo, Ying-Ru; Vitória, Marco

2016-03-03

Curing HIV is a new strategic priority for several major AIDS organizations. In step with this new priority, HIV cure research and related programs are advancing in low, middle, and high-income country settings. This HIV cure momentum may influence existing HIV programs and research priorities. Despite the early stage of ongoing HIV cure efforts, these changes have directly influenced HIV research funding priorities, pilot programs, and HIV messaging. The building momentum to cure HIV infection may synergize with strategic priorities to better identify adults and infants with very early HIV infection. Although HIV cure represents a new goal, many existing programs and research techniques can be repurposed towards an HIV cure. HIV messages focused on engaging communities towards an HIV cure need to be careful to promote ARV adherence and retention within the HIV continuum of care. An increased emphasis within the AIDS field on finding an HIV cure has several important implications. Strengthening connections between HIV cure research and other areas of HIV research may help to catalyze research and facilitate implementation in the future.

Brokering the Research-Practice Gap: A typology.

PubMed

Neal, Jennifer Watling; Neal, Zachary P; Kornbluh, Mariah; Mills, Kristen J; Lawlor, Jennifer A

2015-12-01

Despite widespread recognition of a research-practice gap in multiple service sectors, less is known about how pre-existing communication channels facilitate the flow of information between researchers and practitioners. In the current study, we applied an existing typology of brokerage developed by Gould and Fernandez (Sociol Methodol 19:89-126, 1989) to examine what types of brokerage facilitate information spread between researchers and educational practitioners. Specifically, we conducted semi-structured interviews with 19 school administrators and staff in two public school districts regarding their experiences searching for information about instructional, health, and social skills programs. Using deductive content analysis, we found evidence of all five types of brokerage identified by Gould and Fernandez (1989). However, only three types of brokerage-gatekeepers, representatives, and liaisons-were involved in the flow of information between school administrators and researchers. Moreover, information transfer often occurred in longer chains that involved multiple, distinct types of brokerage. We conclude with the broad implications of our findings for narrowing the research-practice gap by improving researchers' dissemination efforts and practitioners' search for information.

The Canadian Urban Environmental Health Research Consortium - a protocol for building a national environmental exposure data platform for integrated analyses of urban form and health.

PubMed

Brook, Jeffrey R; Setton, Eleanor M; Seed, Evan; Shooshtari, Mahdi; Doiron, Dany

2018-01-08

Multiple external environmental exposures related to residential location and urban form including, air pollutants, noise, greenness, and walkability have been linked to health impacts or benefits. The Canadian Urban Environmental Health Research Consortium (CANUE) was established to facilitate the linkage of extensive geospatial exposure data to existing Canadian cohorts and administrative health data holdings. We hypothesize that this linkage will enable investigators to test a variety of their own hypotheses related to the interdependent associations of built environment features with diverse health outcomes encompassed by the cohorts and administrative data. We developed a protocol for compiling measures of built environment features that quantify exposure; vary spatially on the urban and suburban scale; and can be modified through changes in policy or individual behaviour to benefit health. These measures fall into six domains: air quality, noise, greenness, weather/climate, and transportation and neighbourhood factors; and will be indexed to six-digit postal codes to facilitate merging with health databases. Initial efforts focus on existing data and include estimates of air pollutants, greenness, temperature extremes, and neighbourhood walkability and socioeconomic characteristics. Key gaps will be addressed for noise exposure, with a new national model being developed, and for transportation-related exposures, with detailed estimates of truck volumes and diesel emissions now underway in selected cities. Improvements to existing exposure estimates are planned, primarily by increasing temporal and/or spatial resolution given new satellite-based sensors and more detailed national air quality modelling. Novel metrics are also planned for walkability and food environments, green space access and function and life-long climate-related exposures based on local climate zones. Critical challenges exist, for example, the quantity and quality of input data to many of the models and metrics has changed over time, making it difficult to develop and validate historical exposures. CANUE represents a unique effort to coordinate and leverage substantial research investments and will enable a more focused effort on filling gaps in exposure information, improving the range of exposures quantified, their precision and mechanistic relevance to health. Epidemiological studies may be better able to explore the common theme of urban form and health in an integrated manner, ultimately contributing new knowledge informing policies that enhance healthy urban living.

At the United Nation Foundation's Social Good Summit, Vice President Biden Announces New Cancer Moonshot International Cooperation and Investments | Office of Cancer Clinical Proteomics Research

Cancer.gov

This week, Vice President Joe Biden announced progress on his global vision for the Cancer Moonshot.  Announced were 10 new Memoranda of Understanding or Memoranda of Cooperation for international cancer research and care, as well as new efforts in the emerging scientific areas of precision oncology, the funding of collaborative research centers to address cancer disparities in low- and middle- income (LMIC) countries, and a strengthening of existing U.S. bilateral science and technology engagements around cancer.  

A Systematic Review of Perennial Staple Crops Literature Using Topic Modeling and Bibliometric Analysis

PubMed Central

2016-01-01

Research on perennial staple crops has increased in the past ten years due to their potential to improve ecosystem services in agricultural systems. However, multiple past breeding efforts as well as research on traditional ratoon systems mean there is already a broad body of literature on perennial crops. In this review, we compare the development of research on perennial staple crops, including wheat, rice, rye, sorghum, and pigeon pea. We utilized the advanced search capabilities of Web of Science, Scopus, ScienceDirect, and Agricola to gather a library of 914 articles published from 1930 to the present. We analyzed the metadata in the entire library and in collections of literature on each crop to understand trends in research and publishing. In addition, we applied topic modeling to the article abstracts, a type of text analysis that identifies frequently co-occurring terms and latent topics. We found: 1.) Research on perennials is increasing overall, but individual crops have each seen periods of heightened interest and research activity; 2.) Specialist journals play an important role in supporting early research efforts. Research often begins within communities of specialists or breeders for the individual crop before transitioning to a more general scientific audience; 3.) Existing perennial agricultural systems and their domesticated crop material, such as ratoon rice systems, can provide a useful foundation for breeding efforts, accelerating the development of truly perennial crops and farming systems; 4.) Primary research is lacking for crops that are produced on a smaller scale globally, such as pigeon pea and sorghum, and on the ecosystem service benefits of perennial agricultural systems. PMID:27213283

Turbine Chemistry Modeling

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey; Wey, Thomas

2001-01-01

Many of the engine exhaust species resulting in significant environmental impact exist in trace amounts. Recent research, e.g., conducted at MIT-AM, has pointed to the intra-engine environment as a possible site for important trace chemistry activity. In addition, the key processes affecting the trace species activity occurring downstream in the air passages of the turbine and exhaust nozzle are not well understood. Most recently, an effort has been initiated at NASA Glenn Research Center under the UEET Program to evaluate and further develop CFD-based technology for modeling and simulation of intra-engine trace chemical changes relevant to atmospheric effects of pollutant emissions from aircraft engines. This presentation will describe the current effort conducted at Glenn; some preliminary results relevant to the trace species chemistry in a turbine passage will also be presented to indicate the progress to date.

Faculty and Student Teams and National Laboratories: Expanding the Reach of Research Opportunities and Workforce Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blackburn,N.; White, K.; Stegman, M.

The Faculty and Student Teams (FaST) Program, a cooperative effort between the US Department of Energy (DOE) Office of Science and the National Science Foundation (NSF), brings together collaborative research teams composed of a researcher at Brookhaven National Laboratory, and a faculty member with two or three undergraduate students from a college or university. Begun by the Department of Energy in 2000 with the primary goal of building research capacity at a faculty member's home institution, the FaST Program focuses its recruiting efforts on faculty from colleges and universities with limited research facilities and those institutions that serve populations under-representedmore » in the fields of science, engineering and technology, particularly women and minorities. Once assembled, a FaST team spends a summer engaged in hands-on research working alongside a laboratory scientist. This intensely collaborative environment fosters sustainable relationships between the faulty members and BNL that allow faculty members and their BNL colleagues to submit joint proposals to federal agencies, publish papers in peer-reviewed journals, reform local curriculum, and develop new or expand existing research labs at their home institutions.« less

USING DIVERSE EXPERTISE TO ADVANCE CLIMATE CHANGE FISHERIES SCIENCE.

PubMed

Mulvaney, Kate K; Druschke, Caroline Gottschalk

2017-11-15

As climate change continues to impact New England's coastal ecosystems and their related fisheries, the need for measuring, projecting, interpreting, and applying those impacts for adaptive management is expanding. In New England, different types of formal and informal research efforts that involve collaboration between the fishing community and traditional university and government researchers continue to develop to address some of this need. To better understand the opportunities and challenges that these collaborative research efforts face, we conducted semi-structured interviews with 18 members of the fishing and research communities who are engaged in advancing New England climate change and fisheries science. Participants showed clear concern for the impacts of climate change on New England fisheries and about the insufficient availability of the necessary science to manage for those impacts. They also noted a number of challenges in collaborative research, including poor communication and a lack of trust among fishers, researchers, and decision makers, as well as a lack of perceived credibility for research coming out of the fishing community. We identify a number of opportunities for improving collaboration and communication among these groups, which could build upon the identified value of existing collaborations.

Navy Tactical Ocean Optical Products from the National Polar-orbiting Operational Environmental Satellite System (NPOESS)

NASA Astrophysics Data System (ADS)

Lyon, P. E.; Arnone, R.

2006-12-01

The Naval Research Laboratory at Stennis Space Center (NRLSSC) is preparing to produce optical products for Naval operations support from the National Polar-orbiting Operational Environmental Satellite System (NPOESS). This effort will leverage existing hardware and software systems in place at NRLSSC which are currently used to produce optical products from current sensors SeaWiFS and MODIS Aqua/Terra. This effort is part of an inter agency collaboration between NASA, NOAA, IPO, NRL and the prime contractor for NPOESS, Northrop Grumman / Raytheon. This poster presents an outline of the NRLSSC's plan for achieving the best possible optical products from NPOESS.

Far-Infrared Blocked Impurity Band Detector Development

NASA Technical Reports Server (NTRS)

Hogue, H. H.; Guptill, M. T.; Monson, J. C.; Stewart, J. W.; Huffman, J. E.; Mlynczak, M. G.; Abedin, M. N.

2007-01-01

DRS Sensors & Targeting Systems, supported by detector materials supplier Lawrence Semiconductor Research Laboratory, is developing far-infrared detectors jointly with NASA Langley under the Far-IR Detector Technology Advancement Partnership (FIDTAP). The detectors are intended for spectral characterization of the Earth's energy budget from space. During the first year of this effort we have designed, fabricated, and evaluated pilot Blocked Impurity Band (BIB) detectors in both silicon and germanium, utilizing pre-existing customized detector materials and photolithographic masks. A second-year effort has prepared improved silicon materials, fabricated custom photolithographic masks for detector process, and begun detector processing. We report the characterization results from the pilot detectors and other progress.

Characterization of the Environmentally Induced Chemical Transformations of Uranium Tetrafluoride

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wellons, M.

A key challenge with nuclear safeguards environmental sampling is identification of the materials post release due to subsequent chemical reactions with ambient water and oxygen. Uranium Tetrafluoride (UF4) is of interest as an intermediate in both the upstream and downstream portions of uranium feedstock and metal production processes used in nuclear fuel production; however minimal published research exists relating to UF4 hydrolysis. FY16 efforts were dedicated to in-situ Raman spectroscopy and X-ray diffraction characterization of UF4 during exposure to various relative humidity conditions. This effort mapped several hydrolysis reaction pathways and identified both intermediate, and terminal progeny species.

Bullying.

PubMed

Rettew, David C; Pawlowski, Sara

2016-04-01

Bullying refers to aggressive behavior that is repetitive and intentional in which a power differential exists between the victim and bully. The negative effects of bullying on an individual's mental and physical health are substantial and in line with other major forms of child maltreatment. Efforts to increase detection of bullying are indicated, especially among youth presenting with school phobia, depression, anxiety, and declining school performance. Several antibullying efforts have been developed and promoted at the school and community level. Research indicates that many of these programs are effective and share some common elements that can help reduce the prevalence and impact of bullying. Copyright © 2016 Elsevier Inc. All rights reserved.

Development of TPS flight test and operational instrumentation

NASA Technical Reports Server (NTRS)

Carnahan, K. R.; Hartman, G. J.; Neuner, G. J.

1975-01-01

Thermal and flow sensor instrumentation was developed for use as an integral part of the space shuttle orbiter reusable thermal protection system. The effort was performed in three tasks: a study to determine the optimum instruments and instrument installations for the space shuttle orbiter RSI and RCC TPS; tests and/or analysis to determine the instrument installations to minimize measurement errors; and analysis using data from the test program for comparison to analytical methods. A detailed review of existing state of the art instrumentation in industry was performed to determine the baseline for the departure of the research effort. From this information, detailed criteria for thermal protection system instrumentation were developed.

45 CFR 152.39 - Maintenance of effort.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-EXISTING CONDITION INSURANCE PLAN PROGRAM Relationship to Existing Laws and Programs § 152.39 Maintenance... the contract is entered. (b) Failure to maintain efforts. In situations where a State enters into a..., against any State that fails to maintain funding levels for existing State high risk pools as required...

Building a Semantic Framework for eScience

NASA Astrophysics Data System (ADS)

Movva, S.; Ramachandran, R.; Maskey, M.; Li, X.

2009-12-01

The e-Science vision focuses on the use of advanced computing technologies to support scientists. Recent research efforts in this area have focused primarily on “enabling” use of infrastructure resources for both data and computational access especially in Geosciences. One of the existing gaps in the existing e-Science efforts has been the failure to incorporate stable semantic technologies within the design process itself. In this presentation, we describe our effort in designing a framework for e-Science built using Service Oriented Architecture. Our framework provides users capabilities to create science workflows and mine distributed data. Our e-Science framework is being designed around a mass market tool to promote reusability across many projects. Semantics is an integral part of this framework and our design goal is to leverage the latest stable semantic technologies. The use of these stable semantic technologies will provide the users of our framework the useful features such as: allow search engines to find their content with RDFa tags; create RDF triple data store for their content; create RDF end points to share with others; and semantically mash their content with other online content available as RDF end point.

Water resources management in southern Europe: clues for a research and innovation based regional hypercluster.

PubMed

Martins, G; Brito, A G; Nogueira, R; Ureña, M; Fernández, D; Luque, F J; Alcácer, C

2013-04-15

European countries are facing increasing pressures on their water resources despite stringent regulations and systematic efforts on environmental protection. In this context, research and innovation play a strategic role reinforcing the efficiency of water policies. The present study provides a multilevel assessment of research and innovation practices in the field of water resource management in southern European countries and regions (more specifically; Cyprus, Albania, Poitou-Charentes in France, Andalusia in Spain and the North of Portugal). The analysis was based on a strategic framework aimed at gaining an insight of the current constraints, as well as of the existing and future technological solutions for a better water resource management. The triple helix model proved to be a useful analytical framework for assessing the efforts of different groups towards a common goal. The analysis proved the existence of a significant evolution in the use of technological tools to assist decision-making processes in integrated river basin management in all regions. Nevertheless, the absence of formal channels for knowledge and data exchange between researchers and water resource managers complicates the formers involvement in the decision-making process regarding water allocation. Both researchers and consultants emphasize the low availability of data, together with the need to advance on water resource economics as relevant constraints in the field. The SWOT analysis showed similar concerns among the participating regions and provided a battery of effective projects that resulted in the preparation of a Joint Action Plan. Copyright © 2013 Elsevier Ltd. All rights reserved.

Microgravity Outreach and Education

NASA Technical Reports Server (NTRS)

Rogers, Melissa J. B.; Rosenberg, Carla B.

2000-01-01

The NASA Microgravity Research Program has been actively developing classroom activities and educator's guides since the flight of the First United States Microgravity Laboratory. In addition, various brochures, posters, and exhibit materials have been produced for outreach efforts to the general public and to researchers outside of the program. These efforts are led by the Microgravity Research Outreach/Education team at Marshall Space Flight Center, with classroom material support from the K-12 Educational Program of The National Center for Microgravity Research on Fluids and Combustion (NCMR), general outreach material development by the Microgravity Outreach office at Hampton University, and electronic/media access coordinated by Marshall. The broad concept of the NCMR program is to develop a unique set of microgravity-related educational products that enable effective outreach to the pre-college community by supplementing existing mathematics, science, and technology curricula. The current thrusts of the program include summer teacher and high school internships during which participants help develop educational materials and perform research with NCMR and NASA scientists; a teacher sabbatical program which allows a teacher to concentrate on a major educational product during a full school year; frequent educator workshops held at NASA and at regional and national teachers conferences; a nascent student drop tower experiment competition; presentations and demonstrations at events that also reach the general public; and the development of elementary science and middle school mathematics classroom products. An overview of existing classroom products will be provided, along with a list of pertinent World Wide Web URLs. Demonstrations of some hands on activities will show the audience how simple it can be to bring microgravity into the classroom.

Toward identifying the next generation of superfund and hazardous waste site contaminants.

PubMed

Ela, Wendell P; Sedlak, David L; Barlaz, Morton A; Henry, Heather F; Muir, Derek C G; Swackhamer, Deborah L; Weber, Eric J; Arnold, Robert G; Ferguson, P Lee; Field, Jennifer A; Furlong, Edward T; Giesy, John P; Halden, Rolf U; Henry, Tala; Hites, Ronald A; Hornbuckle, Keri C; Howard, Philip H; Luthy, Richard G; Meyer, Anita K; Sáez, A Eduardo; Vom Saal, Frederick S; Vulpe, Chris D; Wiesner, Mark R

2011-01-01

This commentary evolved from a workshop sponsored by the National Institute of Environmental Health Sciences titled "Superfund Contaminants: The Next Generation" held in Tucson, Arizona, in August 2009. All the authors were workshop participants. Our aim was to initiate a dynamic, adaptable process for identifying contaminants of emerging concern (CECs) that are likely to be found in future hazardous waste sites, and to identify the gaps in primary research that cause uncertainty in determining future hazardous waste site contaminants. Superfund-relevant CECs can be characterized by specific attributes: They are persistent, bioaccumulative, toxic, occur in large quantities, and have localized accumulation with a likelihood of exposure. Although still under development and incompletely applied, methods to quantify these attributes can assist in winnowing down the list of candidates from the universe of potential CECs. Unfortunately, significant research gaps exist in detection and quantification, environmental fate and transport, health and risk assessment, and site exploration and remediation for CECs. Addressing these gaps is prerequisite to a preventive approach to generating and managing hazardous waste sites. A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention.

Functional design to support CDTI/DABS flight experiments

NASA Technical Reports Server (NTRS)

Goka, T.

1982-01-01

The objectives of this project are to: (1) provide a generalized functional design of CDTI avionics using the FAA developd DABS/ATARS ground system as the 'traffic sensor', (2) specify software modifications and/or additions to the existing DABS/ATARS ground system to support CDTI avionics, (3) assess the existing avionics of a NASA research aircraft in terms of CDTI applications, and (4) apply the generalized functional design to provide research flight experiment capability. DABS Data Link Formats are first specified for CDTI flight experiments. The set of CDTI/DABS Format specifications becomes a vehicle to coordinate the CDTI avionics and ground system designs, and hence, to develop overall system requirements. The report is the first iteration of a system design and development effort to support eventual CDTI flight test experiments.

Expendable launch vehicles technology: A report to the US Senate and the US House of Representatives

NASA Technical Reports Server (NTRS)

1990-01-01

As directed in Public Law 100-657, Commercial Space Launch Act Amendments of 1988, and consistent with National Space Policy, NASA has prepared a report on a potential program of research on technologies to reduce the initial and recurring costs, increase reliability, and improve performance of expendable launch vehicles for the launch of commercial and government spacecraft into orbit. The report was developed in consultation with industry and in recognition of relevant ongoing and planned NASA and DoD technology programs which will provide much of the required launch systems technology for U.S. Government needs. Additional efforts which could be undertaken to strengthen the technology base are identified. To this end, focus is on needs for launch vehicle technology development and, in selected areas, includes verification to permit private-sector new technology application at reduced risk. If such a program were to be implemented, it would entail both government and private-sector effort and resources. The additional efforts identified would augment the existing launch vehicle technology programs. The additional efforts identified have not been funded, based upon agency assessments of relative priority vis-a-vis the existing programs. Throughout the consultation and review process, the industry representatives stressed the overriding importance of continuing the DoD/NASA Advanced Launch Development activity and other government technology programs as a primary source of essential launch vehicle technology.

Expendable launch vehicles technology: A report to the US Senate and the US House of Representatives

NASA Astrophysics Data System (ADS)

1990-07-01

As directed in Public Law 100-657, Commercial Space Launch Act Amendments of 1988, and consistent with National Space Policy, NASA has prepared a report on a potential program of research on technologies to reduce the initial and recurring costs, increase reliability, and improve performance of expendable launch vehicles for the launch of commercial and government spacecraft into orbit. The report was developed in consultation with industry and in recognition of relevant ongoing and planned NASA and DoD technology programs which will provide much of the required launch systems technology for U.S. Government needs. Additional efforts which could be undertaken to strengthen the technology base are identified. To this end, focus is on needs for launch vehicle technology development and, in selected areas, includes verification to permit private-sector new technology application at reduced risk. If such a program were to be implemented, it would entail both government and private-sector effort and resources. The additional efforts identified would augment the existing launch vehicle technology programs. The additional efforts identified have not been funded, based upon agency assessments of relative priority vis-a-vis the existing programs. Throughout the consultation and review process, the industry representatives stressed the overriding importance of continuing the DoD/NASA Advanced Launch Development activity and other government technology programs as a primary source of essential launch vehicle technology.

Modeling to Mars: a NASA Model Based Systems Engineering Pathfinder Effort

NASA Technical Reports Server (NTRS)

Phojanamongkolkij, Nipa; Lee, Kristopher A.; Miller, Scott T.; Vorndran, Kenneth A.; Vaden, Karl R.; Ross, Eric P.; Powell, Bobby C.; Moses, Robert W.

2017-01-01

The NASA Engineering Safety Center (NESC) Systems Engineering (SE) Technical Discipline Team (TDT) initiated the Model Based Systems Engineering (MBSE) Pathfinder effort in FY16. The goals and objectives of the MBSE Pathfinder include developing and advancing MBSE capability across NASA, applying MBSE to real NASA issues, and capturing issues and opportunities surrounding MBSE. The Pathfinder effort consisted of four teams, with each team addressing a particular focus area. This paper focuses on Pathfinder team 1 with the focus area of architectures and mission campaigns. These efforts covered the timeframe of February 2016 through September 2016. The team was comprised of eight team members from seven NASA Centers (Glenn Research Center, Langley Research Center, Ames Research Center, Goddard Space Flight Center IV&V Facility, Johnson Space Center, Marshall Space Flight Center, and Stennis Space Center). Collectively, the team had varying levels of knowledge, skills and expertise in systems engineering and MBSE. The team applied their existing and newly acquired system modeling knowledge and expertise to develop modeling products for a campaign (Program) of crew and cargo missions (Projects) to establish a human presence on Mars utilizing In-Situ Resource Utilization (ISRU). Pathfinder team 1 developed a subset of modeling products that are required for a Program System Requirement Review (SRR)/System Design Review (SDR) and Project Mission Concept Review (MCR)/SRR as defined in NASA Procedural Requirements. Additionally, Team 1 was able to perform and demonstrate some trades and constraint analyses. At the end of these efforts, over twenty lessons learned and recommended next steps have been identified.

The Pioneering Role of the Vaccine Safety Datalink Project (VSD) to Advance Collaborative Research and Distributed Data Networks

PubMed Central

Fahey, Kevin R.

2015-01-01

Introduction: Large-scale distributed data networks consisting of diverse stakeholders including providers, patients, and payers are changing health research in terms of methods, speed and efficiency. The Vaccine Safety Datalink (VSD) set the stage for expanded involvement of health plans in collaborative research. Expanding Surveillance Capacity and Progress Toward a Learning Health System: From an initial collaboration of four integrated health systems with fewer than 10 million covered lives to 16 diverse health plans with nearly 100 million lives now in the FDA Sentinel, the expanded engagement of health plan researchers has been essential to increase the value and impact of these efforts. The collaborative structure of the VSD established a pathway toward research efforts that successfully engage all stakeholders in a cohesive rather than competitive manner. The scientific expertise and methodology developed through the VSD such as rapid cycle analysis (RCA) to conduct near real-time safety surveillance allowed for the development of the expanded surveillance systems that now exist. Building on Success and Lessons Learned: These networks have learned from and built on the knowledge base and infrastructure created by the VSD investigators. This shared technical knowledge and experience expedited the development of systems like the FDA’s Mini-Sentinel and the Patient Centered Outcomes Research Institute (PCORI)’s PCORnet Conclusion: This narrative reviews the evolution of the VSD, its contribution to other collaborative research networks, longer-term sustainability of this type of distributed research, and how knowledge gained from the earlier efforts can contribute to a continually learning health system. PMID:26793736

An Integrated Approach to Universal Prevention: Independent and Combined Effects of PBIS and SEL on Youths' Mental Health

ERIC Educational Resources Information Center

Cook, Clayton R.; Frye, Megan; Slemrod, Tal; Lyon, Aaron R.; Renshaw, Tyler L.; Zhang, Yanchen

2015-01-01

Mental health among children and adolescents is a growing national concern and schools have taken center stage in efforts to prevent problems and promote wellness. Although research and policymakers support the integration of mental health services into the schools, there is limited agreement on the ways to package or combine existing supports to…

Refinement of an Instrument to Assess Readiness for Knowledge Management

DTIC Science & Technology

2007-03-01

knowledge from an Aristotlean view of the five types of knowledge: scientific, skills-based, experiential, intuition and theoretical knowledge of...al., 1999). Other researchers have explored the creation of new knowledge in organizations and a number of theories exist that seek to describe how...Holt, Bartczak, Clark, & Trent, 2004; Prusak, 2001), I am not aware of any comprehensive effort that integrates the fundamental theories of

Evaluation of methods for determining hardware projected life

NASA Technical Reports Server (NTRS)

1971-01-01

An investigation of existing methods of predicting hardware life is summarized by reviewing programs having long life requirements, current research efforts on long life problems, and technical papers reporting work on life predicting techniques. The results indicate that there are no accurate quantitative means to predict hardware life for system level hardware. The effectiveness of test programs and the cause of hardware failures is considered.

Using Existing Bibliographic Resources to Compile Faculty Publication Lists: A Case Study from San José State University

ERIC Educational Resources Information Center

Tran, Ngoc-Yen; Chan, Emily K.

2018-01-01

With limited campus resources for faculty scholarship, the College of Science (CoS) at San José State University (SJSU) developed scholarly output metrics as a way to add a quantitative component to the distribution of funds, to ensure objectivity, and to reward proven researchers. To support CoS's efforts to identify and quantify science faculty…

Research-Based Interventions and Practices in Special Education: A Parent's Guide for Understanding. Information and Questions to Ask at IEP Team Meetings

ERIC Educational Resources Information Center

Copenhaver, John; Rudio, Jack

2005-01-01

The No Child Left Behind Act was designed primarily to ensure educational accountability through schools producing positive results or outcomes for educational efforts. With this policy change, a need exists to provide parents information that describes the evidence basis for curriculum materials and interventions that are being used in special…

Fighting 'personhood' initiatives in the United States.

PubMed

Collins, Lee Rubin; Crockin, Susan L

2012-06-01

'Personhood' initiatives filed in many states within the United States threaten to impose potentially significant restrictions on infertility treatment, embryo disposition, pre-natal care, abortion, contraception, and stem-cell research, all through attempts to redefine a 'person' or 'human being' as existing from the moment of fertilization or conception, and endowed with the full legal and Constitutional rights of personhood. Virginia's recent, unsuccessful attempt to pass such legislation provides both a dramatic example of these efforts and valuable lessons in the fight against them by infertility advocates and others. Arguments over loss of infertility treatment seemed more persuasive to legislatures than did restrictions on abortion or stem cell research. Indeed, persuading legislators or voters that they could be 'pro-life' and still anti-personhood initiatives was a key strategy, and consumer efforts and media attention were instrumental. The most central lessons, however, may be the degree of intensity and coordinated strategy to shift public perception that lie behind these numerous state efforts, regardless of whether the actual initiatives are won or lost. Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Stakeholder Perceptions of Risk in Construction.

PubMed

Zhao, Dong; McCoy, Andrew P; Kleiner, Brian M; Mills, Thomas H; Lingard, Helen

2016-02-01

Safety management in construction is an integral effort and its success requires inputs from all stakeholders across design and construction phases. Effective risk mitigation relies on the concordance of all stakeholders' risk perceptions. Many researchers have noticed the discordance of risk perceptions among critical stakeholders in safe construction work, however few have provided quantifiable evidence describing them. In an effort to fill this perception gap, this research performs an experiment that investigates stakeholder perceptions of risk in construction. Data analysis confirms the existence of such discordance, and indicates a trend in risk likelihood estimation. With risk perceptions from low to high, the stakeholders are architects, contractors/safety professionals, and engineers. Including prior studies, results also suggest that designers have improved their knowledge in building construction safety, but compared to builders they present more difficultly in reaching a consensus of perception. Findings of this research are intended to be used by risk management and decision makers to reassess stakeholders' varying judgments when considering injury prevention and hazard assessment.

Stakeholder Perceptions of Risk in Construction

PubMed Central

Zhao, Dong; McCoy, Andrew P.; Kleiner, Brian M.; Mills, Thomas H.; Lingard, Helen

2015-01-01

Safety management in construction is an integral effort and its success requires inputs from all stakeholders across design and construction phases. Effective risk mitigation relies on the concordance of all stakeholders’ risk perceptions. Many researchers have noticed the discordance of risk perceptions among critical stakeholders in safe construction work, however few have provided quantifiable evidence describing them. In an effort to fill this perception gap, this research performs an experiment that investigates stakeholder perceptions of risk in construction. Data analysis confirms the existence of such discordance, and indicates a trend in risk likelihood estimation. With risk perceptions from low to high, the stakeholders are architects, contractors/safety professionals, and engineers. Including prior studies, results also suggest that designers have improved their knowledge in building construction safety, but compared to builders they present more difficultly in reaching a consensus of perception. Findings of this research are intended to be used by risk management and decision makers to reassess stakeholders’ varying judgments when considering injury prevention and hazard assessment. PMID:26441481

Development of ROTC (Reserve Officers’ Training Corps) Data Sets and Evaluation of Their Usefulness for Officer Longitudinal Research Data Base

DTIC Science & Technology

1987-08-01

Two ROTC/OLRDB data sets result from this effort. They reside at the National Institutes of Health (NIH) computer facility. They were both built and...59Z) 1985 8.326 3.836 (46%) Total 31,967 18,617 (58%) Research use of these data sets would benefit from further documentation for some data which...to the existing files, there vould appear to be significant benefit from the inclusion of additional years of OLRDB data vith the newly formed ROTC

Low-rank coal study: national needs for resource development. Volume 6. Peat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-11-01

The requirements and potential for development of US peat resources for energy use are reviewed. Factors analyzed include the occurrence and properties of major peat deposits; technologies for extraction, dewatering, preparation, combustion, and conversion of peat to solid, liquid, or gaseous fuels; environmental, regulatory, and market constraints; and research, development, and demonstration (RD and D) needs. Based on a review of existing research efforts, recommendations are made for a comprehensive national RD and D program to enhance the use of peat as an energy source.

Yield Model Development (YMD) implementation plan for fiscal years 1981 and 1982

NASA Technical Reports Server (NTRS)

Ambroziak, R. A. (Principal Investigator)

1981-01-01

A plan is described for supporting USDA crop production forecasting and estimation by (1) testing, evaluating, and selecting crop yield models for application testing; (2) identifying areas of feasible research for improvement of models; and (3) conducting research to modify existing models and to develop new crop yield assessment methods. Tasks to be performed for each of these efforts are described as well as for project management and support. The responsibilities of USDA, USDC, USDI, and NASA are delineated as well as problem areas to be addressed.

Topographic data requirements for EOS global change research

USGS Publications Warehouse

Gesch, Dean B.

1994-01-01

This document is a result of Earth Observing System Data and Information System (EOSDIS) Version 0 activities of the Land Processes Distributed Active Archive Center at the U.S. Geological Survey's EROS Data Center. A relatively small part of the Version 0 funding provided by NASA is used to address topographic data issues related to EOS. These issues include identifying and improving access to existing sources of topographic data, data generation, facilitating the use of topographic data in global change research by demonstrating derivative products, and inventorying the specific topographic data requirements of EOS investigators. There is a clear need for global topographic data in EOSDIS. Only 10 percent of the global land surface is covered by high-resolution data that are available to the global change science community. Alternative sources for new data exist or have been proposed; however, none of them alone can fulfill the data requirements by the launch of the first EOS platform in 4 years. There is no operational provider of all the source data that are required. Even if appropriate global source data existed, a concerted production effort would be necessary to ensure the existence of the requisite topographic data before EOS launch. Additionally, no funding from NASA or any other agency has been appropriated for a new mapping mission or for other means of data acquisition. This effort to document requirements is an initial step toward understanding the severity of the data shortage. It is well beyond the scope of Version 0 funding and capabilities to provide the required data in the proper timeframe. The shortage of data and the lack of a plan for providing the necessary topographic data through EOSDIS in time for launch are issues that must be addressed by the EOS program.

Indianapolis I3: the third generation Integrated Advanced Information Management Systems*

PubMed Central

McGowan, Julie J.; Overhage, J. Marc; Barnes, Mike; McDonald, Clement J.

2004-01-01

In 2001, the Regenstrief Institute for Health Care and the Indiana University School of Medicine (IUSM) began an IAIMS planning effort to create a vision and a tactical plan for the first Integrated Advanced Information Management Systems (IAIMS) implementation to cross a large area and include unaffiliated institutions. A number of elements made this planning effort unique. Among these elements were the existence of a network infrastructure that supported the Indianapolis Network for Patient Care, the existence of a mature medical informatics program at the Regenstrief Institute, and the existence of a wide-area knowledge network fostered by the IUSM libraries. However, the leadership for a strong information technology role in the IUSM that could promote collaboration in support of education and research across the diverse Indianapolis hospital systems had been lacking. By bringing together various groups, each with a commitment to improve health care quality and public health across the Indianapolis metropolitan area, regardless of individual institutional affiliation, the strategic directions for I3–Indianapolis IAIMS Initiative have been defined and the foundations for a third generation IAIMS construct have been laid in Indianapolis, Indiana. PMID:15098046

The Challenging Road towards a Unified Animal Research Network in Europe

PubMed Central

Martinez-Sanchez, Emma; Leech, Kirk

2015-01-01

Animal models are key in biomedical research as a proof of concept to study complex processes in a physiological context. Despite the small yet crucial role animals play in fundamental and applied research, the value of animal research is recurrently undermined. Lack of openness and transparency encourages misconceptions, which can have a dramatic negative impact on science and medicine. Research centres should use all available resources to ensure that relevant details about their use of animals in research are readily accessible. More concerted efforts by professional advocacy groups devoted to informing about the benefits of biomedical animal research are also crucial. The European Animal Research Association acts as an umbrella organisation providing support to national advocacy groups and coordinating actions in countries in which no advocacy group exists. PMID:26018997

Research support for effective state and community tobacco control programme response to electronic nicotine delivery systems

PubMed Central

Schmitt, Carol L; Lee, Youn Ok; Curry, Laurel E; Farrelly, Matthew C; Rogers, Todd

2014-01-01

Objective To identify unmet research needs of state and community tobacco control practitioners pertaining to electronic nicotine delivery systems (ENDS or e-cigarettes) that would inform policy and practice efforts at the state and community levels, and to describe ENDS-related research and dissemination activities of the National Cancer Institute-funded State and Community Tobacco Control Research Initiative. Methods To determine specific research gaps relevant to state and community tobacco control practice, we analysed survey data collected from tobacco control programmes (TCPs) in all 50 US states and the District of Columbia (N=51). Survey items covered a range of ENDS issues: direct harm to users, harm of secondhand vapour, cessation, flavours, constituents and youth access. Results There is no ENDS topic on which a majority of state TCP managers feel very informed. They feel least informed about harms of secondhand vapour while also reporting that this information is among the most important for their programme. A majority (N=31) of respondents indicated needs for research on the implications of ENDS products for existing policies. Conclusions TCP managers report that ENDS research is highly important for practice and need research-based information to inform decision making around the inclusion of ENDS in existing tobacco control policies. For optimal relevance to state and community TCPs, research on ENDS should prioritise study of the health effects of ENDS use and secondhand exposure to ENDS vapour in the context of existing tobacco control policies. PMID:24935899

Physics Teacher Preparation as a Means for Growth

NASA Astrophysics Data System (ADS)

Henderson, Ron

2013-03-01

Physics departments across the country are experiencing pressures to increase the number of graduates. One response is to improve marketing and recruiting efforts to add students to existing pipelines. A more innovative approach is to create new pathways tied to career paths that are alternatives to graduate school. One occupation that currently needs more graduates than physics departments are supplying is physics teaching. About 3 years ago, MTSU began implementing a strategy to prepare physics majors for careers in high school teaching. These efforts included developing coursework specifically related to physics teaching, creating relationships with the college of education, moving to pedagogies that reflect physics education research (PER)-validated best practices, hiring a tenure-track PER expert, implementing new ways to reach potential majors, and seeking external funding. The cumulative result has not only added a number of physics teaching majors to our roles, but has affected our existing programs in a manner that has yielded further growth. Support provided by the APS/AAPT PhysTEC project.

Common Data Servers as a Foundation for Specialized Services

NASA Astrophysics Data System (ADS)

Burger, E. F.; Schweitzer, R.; O'Brien, K.; Manke, A. B.; Smith, K. M.

2017-12-01

NOAA's Pacific Marine Environmental Laboratory (PMEL) hosts a broad range of research efforts that span many scientific and environmental research disciplines. Many of these research projects have their own data streams that are as diverse as the research. Data are collected using various platforms, including innovative new platforms such as Saildrones and autonomous profilers. With its requirements for public access to federally funded research results and data, the 2013 White House Office of Science and Technology memo on Public Access to Research Results (PARR) changed the data landscape for Federal agencies. In 2015, with support from the PMEL Director, the PMEL Science Data Integration Group (SDIG) initiated a multi-year effort to formulate and implement an integrated data-management strategy for PMEL research efforts. The PMEL integrated data management strategy will provide data access, visualization and some archive services to PMEL data and use existing and proven frameworks for this capability. In addition to these foundational data services, these data access and visualization frameworks are also leveraged to provide enhanced services to scientists. One enhanced service developed is a data management "dashboard". This application provides scientists with a snapshot of their data assets, access to these data, a map view of data locations, and information on the archival status. Ideally, information on the dashboard continually updates to accurately reflect the project's data asset status. This poster explains how frameworks such as ERDDAP and LAS were used as a foundation for the development of custom services, as well as an explanation of the PMEL data management dashboard functionality. We will also highlight accomplishments of the PMEL Integrated data management strategy implementation.

Biomedical Data Sharing and Reuse: Attitudes and Practices of Clinical and Scientific Research Staff.

PubMed

Federer, Lisa M; Lu, Ya-Ling; Joubert, Douglas J; Welsh, Judith; Brandys, Barbara

2015-01-01

Significant efforts are underway within the biomedical research community to encourage sharing and reuse of research data in order to enhance research reproducibility and enable scientific discovery. While some technological challenges do exist, many of the barriers to sharing and reuse are social in nature, arising from researchers' concerns about and attitudes toward sharing their data. In addition, clinical and basic science researchers face their own unique sets of challenges to sharing data within their communities. This study investigates these differences in experiences with and perceptions about sharing data, as well as barriers to sharing among clinical and basic science researchers. Clinical and basic science researchers in the Intramural Research Program at the National Institutes of Health were surveyed about their attitudes toward and experiences with sharing and reusing research data. Of 190 respondents to the survey, the 135 respondents who identified themselves as clinical or basic science researchers were included in this analysis. Odds ratio and Fisher's exact tests were the primary methods to examine potential relationships between variables. Worst-case scenario sensitivity tests were conducted when necessary. While most respondents considered data sharing and reuse important to their work, they generally rated their expertise as low. Sharing data directly with other researchers was common, but most respondents did not have experience with uploading data to a repository. A number of significant differences exist between the attitudes and practices of clinical and basic science researchers, including their motivations for sharing, their reasons for not sharing, and the amount of work required to prepare their data. Even within the scope of biomedical research, addressing the unique concerns of diverse research communities is important to encouraging researchers to share and reuse data. Efforts at promoting data sharing and reuse should be aimed at solving not only technological problems, but also addressing researchers' concerns about sharing their data. Given the varied practices of individual researchers and research communities, standardizing data practices like data citation and repository upload could make sharing and reuse easier.

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities.

PubMed

Pistollato, Francesca; Ohayon, Elan L; Lam, Ann; Langley, Gillian R; Novak, Thomas J; Pamies, David; Perry, George; Trushina, Eugenia; Williams, Robin S B; Roher, Alex E; Hartung, Thomas; Harnad, Stevan; Barnard, Neal; Morris, Martha Clare; Lai, Mei-Chun; Merkley, Ryan; Chandrasekera, P Charukeshi

2016-06-28

Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here we critically discuss these issues in order to determine how existing human-based methods can be applied to study AD pathology and develop novel therapeutics. These methods, which include patient-derived cells, computational analysis and models, together with large-scale epidemiological studies represent novel and exciting tools to enhance and forward AD research. In particular, these methods are helping advance AD research by contributing multifactorial and multidimensional perspectives, especially considering the crucial role played by lifestyle risk factors in the determination of AD risk. In addition to research techniques, we also consider related pitfalls and flaws in the current research funding system. Conversely, we identify encouraging new trends in research and government policy. In light of these new research directions, we provide recommendations regarding prioritization of research funding. The goal of this document is to stimulate scientific and public discussion on the need to explore new avenues in AD research, considering outcome and ethics as core principles to reliably judge traditional research efforts and eventually undertake new research strategies.

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities

PubMed Central

Pistollato, Francesca; Ohayon, Elan L.; Lam, Ann; Langley, Gillian R.; Novak, Thomas J.; Pamies, David; Perry, George; Trushina, Eugenia; Williams, Robin S.B.; Roher, Alex E.; Hartung, Thomas; Harnad, Stevan; Barnard, Neal; Morris, Martha Clare; Lai, Mei-Chun; Merkley, Ryan; Chandrasekera, P. Charukeshi

2016-01-01

Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here we critically discuss these issues in order to determine how existing human-based methods can be applied to study AD pathology and develop novel therapeutics. These methods, which include patient-derived cells, computational analysis and models, together with large-scale epidemiological studies represent novel and exciting tools to enhance and forward AD research. In particular, these methods are helping advance AD research by contributing multifactorial and multidimensional perspectives, especially considering the crucial role played by lifestyle risk factors in the determination of AD risk. In addition to research techniques, we also consider related pitfalls and flaws in the current research funding system. Conversely, we identify encouraging new trends in research and government policy. In light of these new research directions, we provide recommendations regarding prioritization of research funding. The goal of this document is to stimulate scientific and public discussion on the need to explore new avenues in AD research, considering outcome and ethics as core principles to reliably judge traditional research efforts and eventually undertake new research strategies. PMID:27229915

Debating Ethics in HIV Research: Gaps between Policy and Practice in Nigeria.

PubMed

Folayan, Morenike Oluwatoyin; Peterson, Kristin; Haire, Bridget; Brown, Brandon; Audu, Kadiri; Makanjuola, Olumide; Pelemo, Babatunde; Marsh, Vicki

2015-12-01

HIV prevention is a critical health issue in Nigeria; a country that has one of the worst HIV epidemic profiles in the world. With 270,000 new infections in 2012, Nigeria is a prime site for HIV prevention research. One effect of the HIV epidemic has been to revolutionalise ethical norms for the conduct of research: it is now considered unethical to design and implement HIV related studies without community engagement. Unfortunately, there is very little commensurate effort in building the capacity of local persons to engage actively with researchers, and there is no existing platform to facilitate dialogue between researchers and communities engaged in research in Nigeria. In an effort to address this gap, we undertook a series of three community dialogues (Phase One) and two community-researcher interface meetings (Phase Two) in Nigeria. This paper aims to give an empirical account of the dialogue from these community engagement processes and provide a resulting critique of the implementation of research ethics practices in Nigeria. It is anticipated that the outputs will: (i) support researchers in designing community-based research protocols; (ii) inform ethics committees of key considerations during research protocol reviews from a community perspective; and (iii) inform policy makers and research sponsors about issues of primary concern to communities with respect to HIV research. © 2014 John Wiley & Sons Ltd.

A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Xiaohan; Cushman, John C.; Borland, Anne M.

Crassulacean acid metabolism (CAM) is a specialized mode of photosynthesis that features nocturnal CO₂ uptake, facilitates increased water-use efficiency (WUE), and enables CAM plants to inhabit water-limited environments such as semi-arid deserts or seasonally dry forests. Human population growth and global climate change now present challenges for agricultural production systems to increase food, feed, forage, fiber, and fuel production. One approach to meet these challenges is to increase reliance on CAM crops, such as Agave and Opuntia, for biomass production on semi-arid, abandoned, marginal, or degraded agricultural lands. Major research efforts are now underway to assess the productivity of CAMmore » crop species and to harness the WUE of CAM by engineering this pathway into existing food and bioenergy crops. An improved understanding of CAM gained through intensive and expanded research efforts has potential for high returns on research investment in the foreseeable future. To help realize the potential of sustainable dryland agricultural systems, it is necessary to address scientific questions related to the genomic features, regulatory mechanisms, and evolution of CAM; CAM-into-C3 engineering; and the production of CAM crops. Answering these questions requires collaborative efforts to build infrastructure for CAM model systems, field trials, mutant collections, and data management.« less

A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world

DOE PAGES

Yang, Xiaohan; Cushman, John C.; Borland, Anne M.; ...

2015-07-07

Crassulacean acid metabolism (CAM) is a specialized mode of photosynthesis that features nocturnal CO₂ uptake, facilitates increased water-use efficiency (WUE), and enables CAM plants to inhabit water-limited environments such as semi-arid deserts or seasonally dry forests. Human population growth and global climate change now present challenges for agricultural production systems to increase food, feed, forage, fiber, and fuel production. One approach to meet these challenges is to increase reliance on CAM crops, such as Agave and Opuntia, for biomass production on semi-arid, abandoned, marginal, or degraded agricultural lands. Major research efforts are now underway to assess the productivity of CAMmore » crop species and to harness the WUE of CAM by engineering this pathway into existing food and bioenergy crops. An improved understanding of CAM gained through intensive and expanded research efforts has potential for high returns on research investment in the foreseeable future. To help realize the potential of sustainable dryland agricultural systems, it is necessary to address scientific questions related to the genomic features, regulatory mechanisms, and evolution of CAM; CAM-into-C3 engineering; and the production of CAM crops. Answering these questions requires collaborative efforts to build infrastructure for CAM model systems, field trials, mutant collections, and data management.« less

On the lack of consensus over the meaning of openness: an empirical study.

PubMed

Grubb, Alicia M; Easterbrook, Steve M

2011-01-01

This study set out to explore the views and motivations of those involved in a number of recent and current advocacy efforts (such as open science, computational provenance, and reproducible research) aimed at making science and scientific artifacts accessible to a wider audience. Using a exploratory approach, the study tested whether a consensus exists among advocates of these initiatives about the key concepts, exploring the meanings that scientists attach to the various mechanisms for sharing their work, and the social context in which this takes place. The study used a purposive sampling strategy to target scientists who have been active participants in these advocacy efforts, and an open-ended questionnaire to collect detailed opinions on the topics of reproducibility, credibility, scooping, data sharing, results sharing, and the effectiveness of the peer review process. We found evidence of a lack of agreement on the meaning of key terminology, and a lack of consensus on some of the broader goals of these advocacy efforts. These results can be explained through a closer examination of the divergent goals and approaches adopted by different advocacy efforts. We suggest that the scientific community could benefit from a broader discussion of what it means to make scientific research more accessible and how this might best be achieved.

On the Lack of Consensus over the Meaning of Openness: An Empirical Study

PubMed Central

Grubb, Alicia M.; Easterbrook, Steve M.

2011-01-01

This study set out to explore the views and motivations of those involved in a number of recent and current advocacy efforts (such as open science, computational provenance, and reproducible research) aimed at making science and scientific artifacts accessible to a wider audience. Using a exploratory approach, the study tested whether a consensus exists among advocates of these initiatives about the key concepts, exploring the meanings that scientists attach to the various mechanisms for sharing their work, and the social context in which this takes place. The study used a purposive sampling strategy to target scientists who have been active participants in these advocacy efforts, and an open-ended questionnaire to collect detailed opinions on the topics of reproducibility, credibility, scooping, data sharing, results sharing, and the effectiveness of the peer review process. We found evidence of a lack of agreement on the meaning of key terminology, and a lack of consensus on some of the broader goals of these advocacy efforts. These results can be explained through a closer examination of the divergent goals and approaches adopted by different advocacy efforts. We suggest that the scientific community could benefit from a broader discussion of what it means to make scientific research more accessible and how this might best be achieved. PMID:21858110

Dual benefit robotics programs at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, A.T.

Sandia National Laboratories has one of the largest integrated robotics laboratories in the United States. Projects include research, development, and application of one-of-a-kind systems, primarily for the Department of Energy (DOE) complex. This work has been underway for more than 10 years. It began with on-site activities that required remote operation, such as reactor and nuclear waste handling. Special purpose robot systems were developed using existing commercial manipulators and fixtures and programs designed in-house. These systems were used in applications such as servicing the Sandia pulsed reactor and inspecting remote roof bolts in an underground radioactive waste disposal facility. Inmore » the beginning, robotics was a small effort, but with increasing attention to the use of robots for hazardous operations, efforts now involve a staff of more than 100 people working in a broad robotics research, development, and applications program that has access to more than 30 robotics systems.« less

The role of botanic gardens in the science and practice of ecological restoration.

PubMed

Hardwick, Kate A; Fiedler, Peggy; Lee, Lyndon C; Pavlik, Bruce; Hobbs, Richard J; Aronson, James; Bidartondo, Martin; Black, Eric; Coates, David; Daws, Matthew I; Dixon, Kingsley; Elliott, Stephen; Ewing, Kern; Gann, George; Gibbons, David; Gratzfeld, Joachim; Hamilton, Martin; Hardman, David; Harris, Jim; Holmes, Pat M; Jones, Meirion; Mabberley, David; Mackenzie, Andrew; Magdalena, Carlos; Marrs, Robert; Milliken, William; Mills, Anthony; Lughadha, Eimear Nic; Ramsay, Margaret; Smith, Paul; Taylor, Nigel; Trivedi, Clare; Way, Michael; Whaley, Oliver; Hopper, Stephen D

2011-04-01

Many of the skills and resources associated with botanic gardens and arboreta, including plant taxonomy, horticulture, and seed bank management, are fundamental to ecological restoration efforts, yet few of the world's botanic gardens are involved in the science or practice of restoration. Thus, we examined the potential role of botanic gardens in these emerging fields. We believe a reorientation of certain existing institutional strengths, such as plant-based research and knowledge transfer, would enable many more botanic gardens worldwide to provide effective science-based support to restoration efforts. We recommend botanic gardens widen research to include ecosystems as well as species, increase involvement in practical restoration projects and training practitioners, and serve as information hubs for data archiving and exchange. © 2011, Board of Trustees of the Royal Botanic Gardens, Kew Conservation Biology ©2011 Society for Conservation Biology.

Community-Engaged Strategies to Promote Relevance of Research Capacity-Building Efforts Targeting Community Organizations.

PubMed

Cunningham, Jennifer; Miller, Stephania T; Joosten, Yvonne; Elzey, Jared D; Israel, Tiffany; King, Christine; Luther, Patrick; Vaughn, Yolanda; Wilkins, Consuelo H

2015-10-01

The study goal is to highlight strategies for promoting relevance of research capacity-building efforts targeting community organizations (CO)s. Two community partners, representing two COs, were invited to participate in CO research development trainings, Community Research Forums (Forum)s. Their contributions were documented via Forum document review. Forum participants, representatives from other COs, completed post-Forum surveys to identify additional training needs and rate Forum impact relative to their training expectations. A content-based analysis and descriptive statistics were used to summarize needs assessment- and impact-related survey responses, respectively. Community partners were involved in eight Forum-related activities including marketing (planning), facilitation (implementation), and manuscript coauthorship (dissemination). Eighty-one individuals, representing 55 COs, attended the Forums. Needs assessment responses revealed a desire for additional assistance with existing Forum topics (e.g., defining research priorities) and a need for new ones (e.g., promoting organizational buy in for research). Ninety-one percent of participants agreed that the Forum demonstrated the value of research to COs and how to create a research agenda. Including community partners in all Forum phases ensured that CO perspectives were integrated throughout. Post-Forum needs and impact assessment results will help in tailoring, where needed, future training topics and strategies, respectively. © 2015 Wiley Periodicals, Inc.

Opportunities for Cancer Prevention During Midlife

PubMed Central

Holman, Dawn M.; Grossman, Melissa; Henley, S. Jane; Peipins, Lucy A.; Tison, Laura; White, Mary C.

2015-01-01

This paper provides highlights from a CDC-hosted meeting on opportunities for cancer prevention during midlife (roughly ages 45–64 years). Positive changes during this phase of life have the potential to prevent cancer incidence later in life, making this phase an opportune time for targeted prevention efforts to facilitate healthy aging and increased longevity. Risk and protective factors discussed during the meeting included exposure to radiation from medical imaging procedures, circadian disruption, chemical exposures, dietary factors, alcohol consumption, obesity, physical activity, diabetes, and the human microbiome. Although many of these factors are well recognized as being related to cancer incidence, others are not as widely recognized or have emerged as growing areas of research. Meeting participants discussed promising strategies for cancer prevention targeting this age group. Just as there are multiple determinants of cancer risk, there are likely multiple solutions. Changes to social and physical environments may facilitate healthy behaviors and minimize harmful exposures. Information shared during the meeting about health disparities in the U.S. highlighted the need to go beyond traditional approaches to cancer prevention to truly reach vulnerable populations. Partnerships are also a key component to prevention efforts; community-based and nonprofit organizations, the healthcare system, research institutions, state health departments, and federal agencies were all noted as important partners in prevention efforts. Coordinated, multi-disciplinary efforts across multiple chronic diseases may provide opportunities for synergistic effects. Further, leveraging key partnerships and existing communication channels can maximize success and facilitate timely translation of research findings into public health practice. PMID:24512934

Sperm competition games when males invest in paternal care.

PubMed

Requena, Gustavo S; Alonzo, Suzanne H

2017-08-16

Sperm competition games investigate how males partition limited resources between pre- and post-copulatory competition. Although extensive research has explored how various aspects of mating systems affect this allocation, male allocation between mating, fertilization and parental effort has not previously been considered. Yet, paternal care can be energetically expensive and males are generally predicted to adjust their parental effort in response to expected paternity. Here, we incorporate parental effort into sperm competition games, particularly exploring how the relationship between paternal care and offspring survival affects sperm competition and the relationship between paternity and paternal care. Our results support existing expectations that (i) fertilization effort should increase with female promiscuity and (ii) paternal care should increase with expected paternity. However, our analyses also reveal that the cost of male care can drive the strength of these patterns. When paternal behaviour is energetically costly, increased allocation to parental effort constrains allocation to fertilization effort. As paternal care becomes less costly, the association between paternity and paternal care weakens and may even be absent. By explicitly considering variation in sperm competition and the cost of male care, our model provides an integrative framework for predicting the interaction between paternal care and patterns of paternity. © 2017 The Author(s).

A survey of keystroke dynamics biometrics.

PubMed

Teh, Pin Shen; Teoh, Andrew Beng Jin; Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions.

Northwestern University Schizophrenia Data and Software Tool (NUSDAST)

PubMed Central

Wang, Lei; Kogan, Alex; Cobia, Derin; Alpert, Kathryn; Kolasny, Anthony; Miller, Michael I.; Marcus, Daniel

2013-01-01

The schizophrenia research community has invested substantial resources on collecting, managing and sharing large neuroimaging datasets. As part of this effort, our group has collected high resolution magnetic resonance (MR) datasets from individuals with schizophrenia, their non-psychotic siblings, healthy controls and their siblings. This effort has resulted in a growing resource, the Northwestern University Schizophrenia Data and Software Tool (NUSDAST), an NIH-funded data sharing project to stimulate new research. This resource resides on XNAT Central, and it contains neuroimaging (MR scans, landmarks and surface maps for deep subcortical structures, and FreeSurfer cortical parcellation and measurement data), cognitive (cognitive domain scores for crystallized intelligence, working memory, episodic memory, and executive function), clinical (demographic, sibling relationship, SAPS and SANS psychopathology), and genetic (20 polymorphisms) data, collected from more than 450 subjects, most with 2-year longitudinal follow-up. A neuroimaging mapping, analysis and visualization software tool, CAWorks, is also part of this resource. Moreover, in making our existing neuroimaging data along with the associated meta-data and computational tools publically accessible, we have established a web-based information retrieval portal that allows the user to efficiently search the collection. This research-ready dataset meaningfully combines neuroimaging data with other relevant information, and it can be used to help facilitate advancing neuroimaging research. It is our hope that this effort will help to overcome some of the commonly recognized technical barriers in advancing neuroimaging research such as lack of local organization and standard descriptions. PMID:24223551

Northwestern University Schizophrenia Data and Software Tool (NUSDAST).

PubMed

Wang, Lei; Kogan, Alex; Cobia, Derin; Alpert, Kathryn; Kolasny, Anthony; Miller, Michael I; Marcus, Daniel

2013-01-01

The schizophrenia research community has invested substantial resources on collecting, managing and sharing large neuroimaging datasets. As part of this effort, our group has collected high resolution magnetic resonance (MR) datasets from individuals with schizophrenia, their non-psychotic siblings, healthy controls and their siblings. This effort has resulted in a growing resource, the Northwestern University Schizophrenia Data and Software Tool (NUSDAST), an NIH-funded data sharing project to stimulate new research. This resource resides on XNAT Central, and it contains neuroimaging (MR scans, landmarks and surface maps for deep subcortical structures, and FreeSurfer cortical parcellation and measurement data), cognitive (cognitive domain scores for crystallized intelligence, working memory, episodic memory, and executive function), clinical (demographic, sibling relationship, SAPS and SANS psychopathology), and genetic (20 polymorphisms) data, collected from more than 450 subjects, most with 2-year longitudinal follow-up. A neuroimaging mapping, analysis and visualization software tool, CAWorks, is also part of this resource. Moreover, in making our existing neuroimaging data along with the associated meta-data and computational tools publically accessible, we have established a web-based information retrieval portal that allows the user to efficiently search the collection. This research-ready dataset meaningfully combines neuroimaging data with other relevant information, and it can be used to help facilitate advancing neuroimaging research. It is our hope that this effort will help to overcome some of the commonly recognized technical barriers in advancing neuroimaging research such as lack of local organization and standard descriptions.

Designing and implementing an authentic science research program

NASA Astrophysics Data System (ADS)

Rosvally, Harry Edward, Jr.

Science research programs have become a popular elective course in high schools around the country. As the popularity of these programs grows, school districts need a guide by which to implement science research in their own schools. This study sought to provide this information by answering the following questions: (1) What are the most important features in existing research program models? (2) How do schools that have an existing research program define "success"? (3) How do different factors (i.e., budget, professional development, scheduling, recruitment effort, curriculum, and mentors) affect the scope and implementation of a research program? (4) Which features and factors support inclusiveness as a goal for a research program? (5) What kinds of indicators are appropriate for assessing the progress toward an inclusive science research program? After reviewing the literature, six sites with existing research programs were selected for participation in the study. Interviews with teachers and students were conducted during site visits. Interviews with mentors were conducted by telephone. Although the six models in this study were different from one another, there were common characteristics. Students conducted their own review of the literature. Upon completion of the actual research, students published or otherwise communicated their findings to the larger scientific community through regional and national competitions and non-competitive science symposia. This study was also able to identify significant elements that contribute to successful programs. These included: teacher selection; budget requirements; mentor qualities; recruitment and retention practices; and overall structure. As a result of the findings during the research, this study makes recommendations for the successful implementation of a research program.

Completing the Circle: A Model for Effective Community Review of Environmental Health Research

PubMed Central

Shepard, Peggy Morrow; Corbin-Mark, Cecil D.

2009-01-01

While it is well understood that multiple and cumulative environmental stressors negatively impact health at the community level, existing ethical research review procedures are designed to protect individual research participants but not communities. Increasing concerns regarding the ethical conduct of research in general and environmental and genetic research in particular underscore the need to expand the scope of current human participant research regulations and ethical guidelines to include protections for communities. In an effort to address this issue, West Harlem Environmental Action (WE ACT), a nonprofit, community-based environmental justice organization in New York City that has been involved in community–academic partnerships for the past decade, used qualitative interview data to develop a pilot model for community review of environmental health science research. PMID:19890159

Using Web 2.0 for health promotion and social marketing efforts: lessons learned from Web 2.0 experts.

PubMed

Dooley, Jennifer Allyson; Jones, Sandra C; Iverson, Don

2014-01-01

Web 2.0 experts working in social marketing participated in qualitative in-depth interviews. The research aimed to document the current state of Web 2.0 practice. Perceived strengths (such as the viral nature of Web 2.0) and weaknesses (such as the time consuming effort it took to learn new Web 2.0 platforms) existed when using Web 2.0 platforms for campaigns. Lessons learned were identified--namely, suggestions for engaging in specific types of content creation strategies (such as plain language and transparent communication practices). Findings present originality and value to practitioners working in social marketing who want to effectively use Web 2.0.

Removing environmental organic pollutants with bioremediation and phytoremediation.

PubMed

Kang, Jun Won

2014-06-01

Hazardous organic pollutants represent a threat to human, animal, and environmental health. If left unmanaged, these pollutants could cause concern. Many researchers have stepped up efforts to find more sustainable and cost-effective alternatives to using hazardous chemicals and treatments to remove existing harmful pollutants. Environmental biotechnology, such as bioremediation and phytoremediation, is a promising field that utilizes natural resources including microbes and plants to eliminate toxic organic contaminants. This technology offers an attractive alternative to other conventional remediation processes because of its relatively low cost and environmentally-friendly method. This review discusses current biological technologies for the removal of organic contaminants, including chlorinated hydrocarbons, focusing on their limitation and recent efforts to correct the drawbacks.

Apollo Lunar Sample Photographs: Digitizing the Moon Rock Collection

NASA Technical Reports Server (NTRS)

Lofgren, Gary E.; Todd, Nancy S.; Runco, S. K.; Stefanov, W. L.

2011-01-01

The Acquisition and Curation Office at JSC has undertaken a 4-year data restoration project effort for the lunar science community funded by the LASER program (Lunar Advanced Science and Exploration Research) to digitize photographs of the Apollo lunar rock samples and create high resolution digital images. These sample photographs are not easily accessible outside of JSC, and currently exist only on degradable film in the Curation Data Storage Facility

Population as a proxy for infrastructure in the determination of event response and recovery resource allocations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stamber, Kevin L.; Unis, Carl J.; Shirah, Donald N.

Research into modeling of the quantification and prioritization of resources used in the recovery of lifeline critical infrastructure following disruptive incidents, such as hurricanes and earthquakes, has shown several factors to be important. Among these are population density and infrastructure density, event effects on infrastructure, and existence of an emergency response plan. The social sciences literature has a long history of correlating the population density and infrastructure density at a national scale, at a country-to-country level, mainly focused on transportation networks. This effort examines whether these correlations can be repeated at smaller geographic scales, for a variety of infrastructure types,more » so as to be able to use population data as a proxy for infrastructure data where infrastructure data is either incomplete or insufficiently granular. Using the best data available, this effort shows that strong correlations between infrastructure density for multiple types of infrastructure (e.g. miles of roads, hospital beds, miles of electric power transmission lines, and number of petroleum terminals) and population density do exist at known geographic boundaries (e.g. counties, service area boundaries) with exceptions that are explainable within the social sciences literature. Furthermore, the correlations identified provide a useful basis for ongoing research into the larger resource utilization problem.« less

Population as a proxy for infrastructure in the determination of event response and recovery resource allocations

DOE PAGES

Stamber, Kevin L.; Unis, Carl J.; Shirah, Donald N.; ...

2016-04-01

Research into modeling of the quantification and prioritization of resources used in the recovery of lifeline critical infrastructure following disruptive incidents, such as hurricanes and earthquakes, has shown several factors to be important. Among these are population density and infrastructure density, event effects on infrastructure, and existence of an emergency response plan. The social sciences literature has a long history of correlating the population density and infrastructure density at a national scale, at a country-to-country level, mainly focused on transportation networks. This effort examines whether these correlations can be repeated at smaller geographic scales, for a variety of infrastructure types,more » so as to be able to use population data as a proxy for infrastructure data where infrastructure data is either incomplete or insufficiently granular. Using the best data available, this effort shows that strong correlations between infrastructure density for multiple types of infrastructure (e.g. miles of roads, hospital beds, miles of electric power transmission lines, and number of petroleum terminals) and population density do exist at known geographic boundaries (e.g. counties, service area boundaries) with exceptions that are explainable within the social sciences literature. Furthermore, the correlations identified provide a useful basis for ongoing research into the larger resource utilization problem.« less

Lessons from comparative effectiveness research methods development projects funded under the Recovery Act.

PubMed

Zurovac, Jelena; Esposito, Dominick

2014-11-01

The American Recovery and Reinvestment Act of 2009 (ARRA) directed nearly US$29.2 million to comparative effectiveness research (CER) methods development. To help inform future CER methods investments, we describe the ARRA CER methods projects, identify barriers to this research and discuss the alignment of topics with published methods development priorities. We used several existing resources and held discussions with ARRA CER methods investigators. Although funded projects explored many identified priority topics, investigators noted that much work remains. For example, given the considerable investments in CER data infrastructure, the methods development field can benefit from additional efforts to educate researchers about the availability of new data sources and about how best to apply methods to match their research questions and data.

Heteroscedastic Latent Trait Models for Dichotomous Data.

PubMed

Molenaar, Dylan

2015-09-01

Effort has been devoted to account for heteroscedasticity with respect to observed or latent moderator variables in item or test scores. For instance, in the multi-group generalized linear latent trait model, it could be tested whether the observed (polychoric) covariance matrix differs across the levels of an observed moderator variable. In the case that heteroscedasticity arises across the latent trait itself, existing models commonly distinguish between heteroscedastic residuals and a skewed trait distribution. These models have valuable applications in intelligence, personality and psychopathology research. However, existing approaches are only limited to continuous and polytomous data, while dichotomous data are common in intelligence and psychopathology research. Therefore, in present paper, a heteroscedastic latent trait model is presented for dichotomous data. The model is studied in a simulation study, and applied to data pertaining alcohol use and cognitive ability.

Health services and policy research in hepatology.

PubMed

Talwalkar, Jayant A

2014-05-01

This article examines recent health services and policy research studies in hepatology and liver transplantation. Critical issues include access to medical care, timeliness of referral and consultation, resource utilization in clinical practice, comparative effectiveness research, and the evaluation of care delivery models. Despite policymaking efforts, there continues to be unwarranted variation in access to subspecialty care and liver transplantation services based on race and geographic location. Variations in primary care and specialist awareness of practice guidelines for liver disease contribute to disparities in appropriateness and timeliness of treatments. Defining the cost-effectiveness of increased resource utilization for novel antiviral therapies and liver transplantation continues to stimulate controversy. Few comparative effectiveness studies in hepatology exist to date, yet a growing number of analyses using national datasets will help inform policy in this arena. Identifying care delivery models that demonstrate high value for populations with chronic liver disease is critical in the context of recent healthcare reform efforts. Health services and policy research is a growing field of investigation in hepatology and liver transplantation. Further emphasis on research training and workforce development in this area will be critical for understanding and improving patient-centered outcomes for this population.

News media reporting on civil litigation and its influence on civil justice decision making.

PubMed

Robbennolt, Jennifer K; Studebaker, Christina A

2003-02-01

The news media have the potential to act as a powerful influence on the civil litigation system, influencing decision making in particular cases and on the system more generally as media reports influence the decision making of various participants in the system. This paper reviews the research that has examined the relationship between news media reporting and civil litigation and proposes a framework that integrates this work and provides guidance for future research efforts. Specifically, we discuss the nature of media reporting on civil litigation, perceptions of the civil litigation system held by the public and legal actors, and the potential influence of news reporting about civil litigation on the decision making of jurors, judges, civil litigants, and policymakers. Overall, the research suggests that news reporting of civil litigation presents a systematically distorted picture of civil litigation and that this reporting can influence perceptions and outcomes of civil litigation in various ways. However, there are many gaps in the existing research that need to be filled. The proposed organizational scheme helps to identify ways that future research can provide links between the findings of existing research and to identify ways in which this research can be extended to new areas.

Ecological Momentary Assessment and Alcohol Use Disorder Treatment

PubMed Central

Morgenstern, Jon; Kuerbis, Alexis; Muench, Frederick

2014-01-01

The ability to capture real-time data on human behavior inexpensively, efficiently, and accurately holds promise to transform and broaden our understanding of many areas of health science. One approach to acquiring this type of real-time data is ecological momentary assessment (EMA). This method has been used to collect data in many domains of addiction research, including research on the treatment of alcohol use disorders (AUDs). Empirical evidence supports the hypothesis that use of EMA can improve the quality of AUD treatment research when compared with standard assessment methods because it provides more accurate reporting, allows investigators to examine the dynamic unfolding of the behavior change process at an individual level, and can be used to augment and improve clinical assessment and treatment. Overall, the existing literature provides strong support for the advantages of EMA when combined with standard assessment of addictive behaviors in general. Nevertheless, use of EMA in AUD treatment research thus far has been limited, especially in the area of research on mechanisms of behavior change. Existing research indicates, however, that EMA can be used to deliver tailored feedback as a novel and potentially transformative approach to improving AUD treatment. This research area clearly warrants additional future efforts. PMID:26259004

Ethical aspects of the mitigation obstruction argument against climate engineering research.

PubMed

Morrow, David R

2014-12-28

Many commentators fear that climate engineering research might lead policy-makers to reduce mitigation efforts. Most of the literature on this so-called 'moral hazard' problem focuses on the prediction that climate engineering research would reduce mitigation efforts. This paper focuses on a related ethical question: Why would it be a bad thing if climate engineering research obstructed mitigation? If climate engineering promises to be effective enough, it might justify some reduction in mitigation. Climate policy portfolios involving sufficiently large or poorly planned reductions in mitigation, however, could lead to an outcome that would be worse than the portfolio that would be chosen in the absence of further climate engineering research. This paper applies three ethical perspectives to describe the kinds of portfolios that would be worse than that 'baseline portfolio'. The literature on climate engineering identifies various mechanisms that might cause policy-makers to choose these inferior portfolios, but it is difficult to know in advance whether the existence of these mechanisms means that climate engineering research really would lead to a worse outcome. In the light of that uncertainty, a precautionary approach suggests that researchers should take measures to reduce the risk of mitigation obstruction. Several such measures are suggested. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

Contribution mapping: a method for mapping the contribution of research to enhance its impact

PubMed Central

2012-01-01

Background At a time of growing emphasis on both the use of research and accountability, it is important for research funders, researchers and other stakeholders to monitor and evaluate the extent to which research contributes to better action for health, and find ways to enhance the likelihood that beneficial contributions are realized. Past attempts to assess research 'impact' struggle with operationalizing 'impact', identifying the users of research and attributing impact to research projects as source. In this article we describe Contribution Mapping, a novel approach to research monitoring and evaluation that aims to assess contributions instead of impacts. The approach focuses on processes and actors and systematically assesses anticipatory efforts that aim to enhance contributions, so-called alignment efforts. The approach is designed to be useful for both accountability purposes and for assisting in better employing research to contribute to better action for health. Methods Contribution Mapping is inspired by a perspective from social studies of science on how research and knowledge utilization processes evolve. For each research project that is assessed, a three-phase process map is developed that includes the main actors, activities and alignment efforts during research formulation, production and knowledge extension (e.g. dissemination and utilization). The approach focuses on the actors involved in, or interacting with, a research project (the linked actors) and the most likely influential users, who are referred to as potential key users. In the first stage, the investigators of the assessed project are interviewed to develop a preliminary version of the process map and first estimation of research-related contributions. In the second stage, potential key-users and other informants are interviewed to trace, explore and triangulate possible contributions. In the third stage, the presence and role of alignment efforts is analyzed and the preliminary results are shared with relevant stakeholders for feedback and validation. After inconsistencies are clarified or described, the results are shared with stakeholders for learning, improvement and accountability purposes. Conclusion Contribution Mapping provides an interesting alternative to existing methods that aim to assess research impact. The method is expected to be useful for research monitoring, single case studies, comparing multiple cases and indicating how research can better be employed to contribute to better action for health. PMID:22748169

Design Methods and Optimization for Morphing Aircraft

NASA Technical Reports Server (NTRS)

Crossley, William A.

2005-01-01

This report provides a summary of accomplishments made during this research effort. The major accomplishments are in three areas. The first is the use of a multiobjective optimization strategy to help identify potential morphing features that uses an existing aircraft sizing code to predict the weight, size and performance of several fixed-geometry aircraft that are Pareto-optimal based upon on two competing aircraft performance objectives. The second area has been titled morphing as an independent variable and formulates the sizing of a morphing aircraft as an optimization problem in which the amount of geometric morphing for various aircraft parameters are included as design variables. This second effort consumed most of the overall effort on the project. The third area involved a more detailed sizing study of a commercial transport aircraft that would incorporate a morphing wing to possibly enable transatlantic point-to-point passenger service.

Advanced High Energy Density Secondary Batteries with Multi‐Electron Reaction Materials

PubMed Central

Luo, Rui; Huang, Yongxin; Li, Li

2016-01-01

Secondary batteries have become important for smart grid and electric vehicle applications, and massive effort has been dedicated to optimizing the current generation and improving their energy density. Multi‐electron chemistry has paved a new path for the breaking of the barriers that exist in traditional battery research and applications, and provided new ideas for developing new battery systems that meet energy density requirements. An in‐depth understanding of multi‐electron chemistries in terms of the charge transfer mechanisms occuring during their electrochemical processes is necessary and urgent for the modification of secondary battery materials and development of secondary battery systems. In this Review, multi‐electron chemistry for high energy density electrode materials and the corresponding secondary battery systems are discussed. Specifically, four battery systems based on multi‐electron reactions are classified in this review: lithium‐ and sodium‐ion batteries based on monovalent cations; rechargeable batteries based on the insertion of polyvalent cations beyond those of alkali metals; metal–air batteries, and Li–S batteries. It is noted that challenges still exist in the development of multi‐electron chemistries that must be overcome to meet the energy density requirements of different battery systems, and much effort has more effort to be devoted to this. PMID:27840796

Mobile health in China: a review of research and programs in medical care, health education, and public health.

PubMed

Corpman, David W

2013-01-01

There are nearly 1 billion mobile phone subscribers in China. Health care providers, telecommunications companies, technology firms, and Chinese governmental organizations use existing mobile technology and social networks to improve patient-provider communication, promote health education and awareness, add efficiency to administrative practices, and enhance public health campaigns. This review of mobile health in China summarizes existing clinical research and public health text messaging campaigns while highlighting potential future areas of research and program implementation. Databases and search engines served as the primary means of gathering relevant resources. Included material largely consists of scientific articles and official reports that met predefined inclusion criteria. This review includes 10 reports of controlled studies that assessed the use of mobile technology in health care settings and 17 official reports of public health awareness campaigns that used text messaging. All source material was published between 2006 and 2011. The controlled studies suggested that mobile technology interventions significantly improved an array of health care outcomes. However, additional efforts are needed to refine mobile health research and better understand the applicability of mobile technology in China's health care settings. A vast potential exists for the expansion of mobile health in China, especially as costs decrease and increasingly sophisticated technology becomes more widespread.

Scientists' perspectives on the ethical issues of stem cell research.

PubMed

Longstaff, Holly; Schuppli, Catherine A; Preto, Nina; Lafrenière, Darquise; McDonald, Michael

2009-06-01

This paper describes findings from an ethics education project funded by the Canadian Stem Cell Network (SCN). The project is part of a larger research initiative entitled "The Stem Cell Research Environment: Drawing the Evidence and Experience Together". The ethics education study began with a series of focus groups with SCN researchers and trainees as part of a "needs assessment" effort. The purpose of these discussions was to identify the main ethical issues associated with stem cell (SC) research from the perspective of the stem cell community. This paper will focus on five prominent themes that emerged from the focus group data including: (1) the source of stem cells; (2) the power of stem cells; (3) working within a charged research environment; (4) the regulatory context; and (5) ethics training for scientists. Additional discussions are planned with others involved in Canadian stem cell research (e.g., research ethics board members, policy makers) to supplement initial findings. These assessment results combined with existing bioethics literature will ultimately inform a web-based ethics education module for the SCN. We believe that our efforts are important for those analyzing the ethical, legal, and social issues (ELSI) in this area because our in depth understanding of stem cell researcher perspectives will enable us to develop more relevant and effective education material, which in turn should help SC researchers address the important ethical challenges in their area.

Liquid Oxygen/Liquid Methane Component Technology Development at MSFC

NASA Technical Reports Server (NTRS)

Robinson, Joel W.

2010-01-01

The National Aeronautics & Space Administration (NASA) has identified Liquid Oxygen (LOX)/Liquid Methane (LCH4) as a potential propellant combination for future space vehicles based upon exploration studies. The technology is estimated to have higher performance and lower overall systems mass compared to existing hypergolic propulsion systems. Besides existing in-house risk reduction activities, NASA has solicited from industry their participation on component technologies based on the potential application to the lunar ascent main engine (AME). Contracted and NASA efforts have ranged from valve technologies to engine system testbeds. The application for the AME is anticipated to be an expendable, pressure-fed engine for ascent from the moon at completion of its lunar stay. Additionally, the hardware is expected to provide an abort capability prior to landing, in the event that descent systems malfunction. For the past 4 years, MSFC has been working with the Glenn Research Center and the Johnson Space Center on methane technology development. This paper will focus on efforts specific to MSFC in pursuing ignition, injector performance, chamber material assessments and cryogenic valve technologies. Ignition studies have examined characteristics for torch, spark and microwave systems. Injector testing has yielded insight into combustion performance for shear, swirl and impinging type injectors. The majority of chamber testing has been conducted with ablative and radiatively cooled chambers with planned activities for regenerative and transpiration cooled chambers. Lastly, an effort is underway to examine the long duration exposure issues of cryogenic valve internal components. The paper will summarize the status of these efforts.

Delivering vaccines to the people who need them most

PubMed Central

Barocchi, Michèle Anne; Rappuoli, Rino

2015-01-01

Thanks to the Global Alliance for Vaccines and Immunization (GAVI), the Vaccine Fund and the Bill & Melinda Gates Foundation, the global health community has made enormous progress in providing already existing vaccines to developing countries. However, there still exists a gap to develop vaccines for which there is no market in the Western world, owing to low economic incentives for the private sector to justify the investments necessary for vaccine development. In many cases, industry has the technologies, but lacks the impetus to direct resources to develop these vaccine products. The present emergency with the Ebola vaccine provides us an excellent example where a vaccine was feasible several years ago, but the global health community waited for a humanitarian disaster to direct efforts and resources to develop this vaccine. In the beginning of 2015, the first large-scale trials of two experimental vaccines against Ebola virus disease have begun in West Africa. During the past few years, several institutions have dedicated efforts to the development of vaccines against diseases present only in low-income countries. These include the International Vaccine Institute, the Novartis Vaccines Institute for Global Health, the Hilleman Institute, the Sabin Vaccine Institute and the Infectious Disease Research Institute. Nevertheless, solving this problem requires a more significant global effort than that currently invested. These efforts include a clear policy, global coordination of funds dedicated to the development of neglected disease and an agreement on regulatory strategies and incentives for the private sector. PMID:25964460

EPOS-IP WP10: services and data provision for the GNSS community

NASA Astrophysics Data System (ADS)

Fernandes, Rui

2016-04-01

The EPOS-IP WP10 - "GNSS Data & Products" is the Working Package of the EPOS-IP project in charge of implementing the necessary services in order that the geo-sciences community can access the existing Pan-European Geodetic Infrastructures. The WP10 is formed by representatives of the participating institutions (10) but it is also open to the entire geodetic community. In fact, WP10 also includes members from other institutions/countries that formally are not participating in the EPOS-IP. During the EPOS-IP project, the geodetic component of EPOS (WP10) is dealing essentially with Research Infrastructures focused on continuous operating GNSS (cGNSS). The option of concentrating the efforts on the presently most generalized geodetic tool supporting research on Solid Earth was decided in order to optimize the existing resources. Furthermore, although the focus is on Solid Earth applications, other research and technical applications (e.g., reference frames, meteorology, space weather) can also benefit from the efforts of WP10 towards the optimization of the geodetic resources in Europe. We will present and discuss the plans for the implementation of the thematic and core services (TCS) for GNSS data within EPOS and the related business plan. We will focus on strategies towards the implementation of the best solutions that will permit to the end-users, and in particular geo-scientists, to access the geodetic data, derived solutions, and associated metadata using transparent and uniform processes. The collaboration with EUREF is also an essential component of the implementation plan.

Toward Identifying the Next Generation of Superfund and Hazardous Waste Site Contaminants

PubMed Central

Ela, Wendell P.; Sedlak, David L.; Barlaz, Morton A.; Henry, Heather F.; Muir, Derek C.G.; Swackhamer, Deborah L.; Weber, Eric J.; Arnold, Robert G.; Ferguson, P. Lee; Field, Jennifer A.; Furlong, Edward T.; Giesy, John P.; Halden, Rolf U.; Henry, Tala; Hites, Ronald A.; Hornbuckle, Keri C.; Howard, Philip H.; Luthy, Richard G.; Meyer, Anita K.; Sáez, A. Eduardo; vom Saal, Frederick S.; Vulpe, Chris D.; Wiesner, Mark R.

2011-01-01

Background This commentary evolved from a workshop sponsored by the National Institute of Environmental Health Sciences titled “Superfund Contaminants: The Next Generation” held in Tucson, Arizona, in August 2009. All the authors were workshop participants. Objectives Our aim was to initiate a dynamic, adaptable process for identifying contaminants of emerging concern (CECs) that are likely to be found in future hazardous waste sites, and to identify the gaps in primary research that cause uncertainty in determining future hazardous waste site contaminants. Discussion Superfund-relevant CECs can be characterized by specific attributes: They are persistent, bioaccumulative, toxic, occur in large quantities, and have localized accumulation with a likelihood of exposure. Although still under development and incompletely applied, methods to quantify these attributes can assist in winnowing down the list of candidates from the universe of potential CECs. Unfortunately, significant research gaps exist in detection and quantification, environmental fate and transport, health and risk assessment, and site exploration and remediation for CECs. Addressing these gaps is prerequisite to a preventive approach to generating and managing hazardous waste sites. Conclusions A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention. PMID:21205582

Joint federal research and development process to meet state and local needs. Part 1. Science and technology and political decision making

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wise, H F; Smith, L K; Einsweiler, R C

This part of the handbook addresses the basic how to do it - how states and local governments can identify complex and cross-cutting issues and develop and manage scientific and technical resources in seeking policy solutions to such issues. The following subjects are discussed: background statement of the issue; the research/decision-making process; defining problems and identifying research components; research and decision-making strategies; how to identify existing knowledge or ongoing research in the area of policy concern; and managing multi-disciplinary research. The fourteen agencies involved in this effort include: US Departments of Energy, Agriculture, Transportation, Housing and Urban Development, Environmental Protectionmore » Agency, and National Science Foundation. (PSB)« less

The quest for tissue stem cells in the pancreas and other organs, and their application in beta-cell replacement.

PubMed

Houbracken, Isabelle; Bouwens, Luc

2010-01-01

Adult stem cell research has drawn a lot of attention by many researchers, due to its medical hope of cell replacement or regenerative therapy for diabetes patients. Despite the many research efforts to date, there is no consensus on the existence of stem cells in adult pancreas. Genetic lineage tracing experiments have put into serious doubt whether β-cell neogenesis from stem/progenitor cells takes place postnatally. Different in vitro experiments have suggested centroacinar, ductal, acinar, stellate, or yet unidentified clonigenic cells as candidate β-cell progenitors. As in the rest of the adult stem cell field, sound and promising observations have been made. However, these observations still need to be replicated. As an alternative to committed stem/progenitor cells in the pancreas, transdifferentiation or lineage reprogramming of exocrine acinar and endocrine α-cells may be used to generate new β-cells. At present, it is unclear which approach is most medically promising. This article highlights the progress being made in knowledge about tissue stem cells, their existence and availability for therapy in diabetes. Particular attention is given to the assessment of methods to verify the existence of tissue stem cells.

Promoting Lifelong Ocean Education: Shaping Tomorrow's Earth Stewards and the Science and Technology Workforce

NASA Technical Reports Server (NTRS)

Meeson, Blanche

2006-01-01

The coming ocean observing systems provide an unprecedented opportunity to change both the public perception of our oceans, and to inspire, captivate and motivate our children, our young adults and even our fellow adults to pursue careers allied with the oceans and to become stewards of our Planet's last unexplored environment. Education plans for the operational component, the Integrated Ocean Observing System (IOOS), and for the research component, Ocean Research Interactive Observatory Networks (ORION), are designed to take advantage of this opportunity. In both cases, community recommendations were developed within the context of the following assumptions: 1. Utilize research on how people learn, especially the four-pronged model of simultaneous learner-centered, knowledge-center, assessment-centered and community-centered learning 2. Strive for maximum impact on national needs in science and technology learning 3. Build on the best of what is already in place 4. Pay special attention to quality, sustainability, and scalability of efforts 5. Use partnerships across federal, state and local government, academia, and industry. Community recommendations for 100s and ORION education have much in common and offer the opportunity to create a coherent education effort allied with ocean observing systems. Both efforts focus on developing the science and technology workforce of the future, and the science and technology literacy of the public within the context of the Earth system and the role of the oceans and Great Lakes in that system. Both also recognize that an organized education infrastructure that supports sustainability and scalability of education efforts is required if ocean observing education efforts are to achieve a small but measurable improvement in either of these areas. Efforts have begun to develop the education infrastructure by beginning to form a community of educators from existing ocean and aquatic education networks and by exploring needs and issues associated with using ocean observing information assets in education. Likewise efforts are underway to address workforce issues by a systematic analysis of current and future workforce and educational needs. These activities will be described as will upcoming opportunities for the community to participate in these efforts.

Practical lessons for bringing policy-makers on board in sexual and reproductive health research.

PubMed

Guieu, Aurore; Zhang, Wei-Hong; Lafort, Yves; Decat, Peter; De Meyer, Sara; Wang, Shuchen; Kerstens, Birgit; Duysburgh, Els

2016-11-11

The need to translate research into policy, i.e. making research findings a driving force in agenda-setting and policy change, is increasingly acknowledged. However, little is known about translation mechanisms in the field of sexual and reproductive health (SRH) outside North American or European contexts. This paper seeks to give an overview of the existing knowledge on this topic as well as to document practical challenges and remedies from the perspectives of researchers involved in four SRH research consortium projects in Latin America, sub-Saharan Africa, China and India. A literature review and relevant project documents were used to develop an interview guide through which researchers could reflect on their experiences in engaging with policy-makers, and particularly on the obstacles met and the strategies deployed by the four project consortia to circumvent them. Our findings confirm current recommendations on an early and steady involvement of policy-makers, however they also suggest that local barriers between researchers and policy-making spheres and individuals can represent major hindrances to the realization of translation objectives. Although many of the challenges might be common to different contexts, creating locally-adapted responses is deemed key to overcome them. Researchers' experiences also indicate that - although inevitable - recognizing and addressing these challenges is a difficult, time- and energy-consuming process for all partners involved. Despite a lack of existing knowledge on translation efforts in SRH research outside North American or European contexts, and more particularly in low and middle-income countries, it is clear that existing pressure on health and policy systems in these settings further complicates them. This article brings together literature findings and researchers' own experiences in translating research results into policy and highlights the major challenges research conducted on sexual and reproductive health outside North American or European contexts can meet. Future SRH projects should be particularly attentive to these potential obstacles in order to tailor appropriate and consistent strategies within their existing resources.

Building a Community of Practice for Researchers: The International Network for Simulation-Based Pediatric Innovation, Research and Education.

PubMed

Cheng, Adam; Auerbach, Marc; Calhoun, Aaron; Mackinnon, Ralph; Chang, Todd P; Nadkarni, Vinay; Hunt, Elizabeth A; Duval-Arnould, Jordan; Peiris, Nicola; Kessler, David

2018-06-01

The scope and breadth of simulation-based research is growing rapidly; however, few mechanisms exist for conducting multicenter, collaborative research. Failure to foster collaborative research efforts is a critical gap that lies in the path of advancing healthcare simulation. The 2017 Research Summit hosted by the Society for Simulation in Healthcare highlighted how simulation-based research networks can produce studies that positively impact the delivery of healthcare. In 2011, the International Network for Simulation-based Pediatric Innovation, Research and Education (INSPIRE) was formed to facilitate multicenter, collaborative simulation-based research with the aim of developing a community of practice for simulation researchers. Since its formation, the network has successfully completed and published numerous collaborative research projects. In this article, we describe INSPIRE's history, structure, and internal processes with the goal of highlighting the community of practice model for other groups seeking to form a simulation-based research network.

“Shovel-ready” Sequences as a Stimulus for the Next Generation of Life Scientists

PubMed Central

Boyle, Michael D.

2010-01-01

Genomics and bioinformatics are dynamic fields well-suited for capturing the imagination of undergraduates in both research laboratories and classrooms. Currently, raw nucleotide sequence is being provided, as part of several genomics research initiatives, for undergraduate research and teaching. These initiatives could be easily extended and much more effective if the source of the sequenced material and the subsequent focus of the data analysis were aligned with the research interests of individual faculty at undergraduate institutions. By judicious use of surplus capacity in existing nucleotide sequencing cores, raw sequence data could be generated to support ongoing research efforts involving undergraduates. This would allow these students to participate actively in discovery research, with a goal of making novel contributions to their field through original research while nurturing the next generation of talented research scientists. PMID:23653696

"Shovel-ready" Sequences as a Stimulus for the Next Generation of Life Scientists.

PubMed

Boyle, Michael D

2010-01-01

Genomics and bioinformatics are dynamic fields well-suited for capturing the imagination of undergraduates in both research laboratories and classrooms. Currently, raw nucleotide sequence is being provided, as part of several genomics research initiatives, for undergraduate research and teaching. These initiatives could be easily extended and much more effective if the source of the sequenced material and the subsequent focus of the data analysis were aligned with the research interests of individual faculty at undergraduate institutions. By judicious use of surplus capacity in existing nucleotide sequencing cores, raw sequence data could be generated to support ongoing research efforts involving undergraduates. This would allow these students to participate actively in discovery research, with a goal of making novel contributions to their field through original research while nurturing the next generation of talented research scientists.

Pika: A snow science simulation tool built using the open-source framework MOOSE

NASA Astrophysics Data System (ADS)

Slaughter, A.; Johnson, M.

2017-12-01

The Department of Energy (DOE) is currently investing millions of dollars annually into various modeling and simulation tools for all aspects of nuclear energy. An important part of this effort includes developing applications based on the open-source Multiphysics Object Oriented Simulation Environment (MOOSE; mooseframework.org) from Idaho National Laboratory (INL).Thanks to the efforts of the DOE and outside collaborators, MOOSE currently contains a large set of physics modules, including phase-field, level set, heat conduction, tensor mechanics, Navier-Stokes, fracture and crack propagation (via the extended finite-element method), flow in porous media, and others. The heat conduction, tensor mechanics, and phase-field modules, in particular, are well-suited for snow science problems. Pika--an open-source MOOSE-based application--is capable of simulating both 3D, coupled nonlinear continuum heat transfer and large-deformation mechanics applications (such as settlement) and phase-field based micro-structure applications. Additionally, these types of problems may be coupled tightly in a single solve or across length and time scales using a loosely coupled Picard iteration approach. In addition to the wide range of physics capabilities, MOOSE-based applications also inherit an extensible testing framework, graphical user interface, and documentation system; tools that allow MOOSE and other applications to adhere to nuclear software quality standards. The snow science community can learn from the nuclear industry and harness the existing effort to build simulation tools that are open, modular, and share a common framework. In particular, MOOSE-based multiphysics solvers are inherently parallel, dimension agnostic, adaptive in time and space, fully coupled, and capable of interacting with other applications. The snow science community should build on existing tools to enable collaboration between researchers and practitioners throughout the world, and advance the state-of-the-art in line with other scientific research efforts.

Whooping crane recovery plan

USGS Publications Warehouse

Olsen, David L.; Blankenship, David R.; Irby, Harold D.; Erickson, Ray C.; Lock, Ross; Drewien, Roderick C.; Smith, Lawrence S.; Derrickson, Scott R.

1980-01-01

This plan has been prepared under the authority of the Endangered Species Act of 1973 and subsequent amendments. The Plan is designed to provide decision makers with an orderly set of events which, if carried out to a successful completion, will result in changing the status of the species from the endangered to the threatened level. It must be recognized that this Plan has been prepared 40 years after attempts to preserve the species began. As such, it covers events that have taken place, that are taking place, and that need to take place. The Plan, therefore, not only compiles in one place all whooping crane management and research efforts which are underway, but also proposes additional efforts needed for the recovery of the whooping crane. The Plan also establishes funding evels, time schedules, and priorities for each management and research effort.The Plan is organized into three parts. the first part includes an account of the whooping crane's history, biology, present status, and the factors believed to have resulted in its endangered status. Also included in this part is a synopsis of research and management activities that have taken place through 1978.The second part is a step-down pan wherein all existing and needed research and management efforts are organized into an orderly set of events. The prime objective is to move the whooping crane to non-endangered status. Minimum requirements for the attainment of this objective are the increase of the historical Wood Buffalo-Aransas population to at least 40 nesting pairs and the establishment of at least two additional, separate, and self-sustaining populations consisting of at least 20 nesting pairs each.the third part identifies the responsibility, time schedule, and cost for each element of the step-down plan.

Targeting Hispanic populations: future research and prevention strategies.

PubMed Central

Ramirez, A G; McAlister, A; Gallion, K J; Villarreal, R

1995-01-01

Minority populations face a wide variety of economic, institutional, and cultural barriers to health care. These barriers and low levels of education and income pose significant challenges for health professionals in developing cancer research and prevention-control strategies. It is suggested that specific segments of Hispanic populations fit the model of an underdeveloped country in the intermediate stage of epidemiological transition. Since noncommunicable diseases have not yet fully emerged in some of these Hispanic population segments, the opportunity exists to apply primordial prevention strategies. Such campaigns would focus on dissuading members of these populations from adopting negative health behaviors while promoting positive lifestyle choices. Optimal programs would increase cancer screening participation and discourage risk behaviors through community-oriented, population-based interventions. Future directions in prevention and control efforts for minority populations should include expanded health insurance coverage, improved access to health care, greater emphasis on minority recruitment in health care fields, focused epidemiologic and clinical research, and identification and replication of effective components within existing prevention-control programs. PMID:8741800

Children With Medical Complexity: An Emerging Population for Clinical and Research Initiatives

PubMed Central

Kuo, Dennis Z.; Agrawal, Rishi; Berry, Jay G.; Bhagat, Santi K. M.; Simon, Tamara D.; Srivastava, Rajendu

2011-01-01

Children with medical complexity (CMC) have medical fragility and intensive care needs that are not easily met by existing health care models. CMC may have a congenital or acquired multisystem disease, a severe neurologic condition with marked functional impairment, and/or technology dependence for activities of daily living. Although these children are at risk of poor health and family outcomes, there are few well-characterized clinical initiatives and research efforts devoted to improving their care. In this article, we present a definitional framework of CMC that consists of substantial family-identified service needs, characteristic chronic and severe conditions, functional limitations, and high health care use. We explore the diversity of existing care models and apply the principles of the chronic care model to address the clinical needs of CMC. Finally, we suggest a research agenda that uses a uniform definition to accurately describe the population and to evaluate outcomes from the perspectives of the child, the family, and the broader health care system. PMID:21339266

Turbulence Modeling Workshop

NASA Technical Reports Server (NTRS)

Rubinstein, R. (Editor); Rumsey, C. L. (Editor); Salas, M. D. (Editor); Thomas, J. L. (Editor); Bushnell, Dennis M. (Technical Monitor)

2001-01-01

Advances in turbulence modeling are needed in order to calculate high Reynolds number flows near the onset of separation and beyond. To this end, the participants in this workshop made the following recommendations. (1) A national/international database and standards for turbulence modeling assessment should be established. Existing experimental data sets should be reviewed and categorized. Advantage should be taken of other efforts already under-way, such as that of the European Research Community on Flow, Turbulence, and Combustion (ERCOFTAC) consortium. Carefully selected "unit" experiments will be needed, as well as advances in instrumentation, to fill the gaps in existing datasets. A high priority should be given to document existing turbulence model capabilities in a standard form, including numerical implementation issues such as grid quality and resolution. (2) NASA should support long-term research on Algebraic Stress Models and Reynolds Stress Models. The emphasis should be placed on improving the length-scale equation, since it is the least understood and is a key component of two-equation and higher models. Second priority should be given to the development of improved near-wall models. Direct Numerical Simulations (DNS) and Large Eddy Simulations (LES) would provide valuable guidance in developing and validating new Reynolds-averaged Navier-Stokes (RANS) models. Although not the focus of this workshop, DNS, LES, and hybrid methods currently represent viable approaches for analysis on a limited basis. Therefore, although computer limitations require the use of RANS methods for realistic configurations at high Reynolds number in the foreseeable future, a balanced effort in turbulence modeling development, validation, and implementation should include these approaches as well.

Technical Note: Harmonizing met-ocean model data via standard web services within small research groups

USGS Publications Warehouse

Signell, Richard; Camossi, E.

2016-01-01

Work over the last decade has resulted in standardised web services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by (1) making it simple for providers to enable web service access to existing output files; (2) using free technologies that are easy to deploy and configure; and (3) providing standardised, service-based tools that work in existing research environments. We present a simple, local brokering approach that lets modellers continue to use their existing files and tools, while serving virtual data sets that can be used with standardised tools. The goal of this paper is to convince modellers that a standardised framework is not only useful but can be implemented with modest effort using free software components. We use NetCDF Markup language for data aggregation and standardisation, the THREDDS Data Server for data delivery, pycsw for data search, NCTOOLBOX (MATLAB®) and Iris (Python) for data access, and Open Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.

Technical note: Harmonising metocean model data via standard web services within small research groups

NASA Astrophysics Data System (ADS)

Signell, Richard P.; Camossi, Elena

2016-05-01

Work over the last decade has resulted in standardised web services and tools that can significantly improve the efficiency and effectiveness of working with meteorological and ocean model data. While many operational modelling centres have enabled query and access to data via common web services, most small research groups have not. The penetration of this approach into the research community, where IT resources are limited, can be dramatically improved by (1) making it simple for providers to enable web service access to existing output files; (2) using free technologies that are easy to deploy and configure; and (3) providing standardised, service-based tools that work in existing research environments. We present a simple, local brokering approach that lets modellers continue to use their existing files and tools, while serving virtual data sets that can be used with standardised tools. The goal of this paper is to convince modellers that a standardised framework is not only useful but can be implemented with modest effort using free software components. We use NetCDF Markup language for data aggregation and standardisation, the THREDDS Data Server for data delivery, pycsw for data search, NCTOOLBOX (MATLAB®) and Iris (Python) for data access, and Open Geospatial Consortium Web Map Service for data preview. We illustrate the effectiveness of this approach with two use cases involving small research modelling groups at NATO and USGS.

Large-Scale Demonstration of Liquid Hydrogen Storage with Zero Boiloff for In-Space Applications

NASA Technical Reports Server (NTRS)

Hastings, L. J.; Bryant, C. B.; Flachbart, R. H.; Holt, K. A.; Johnson, E.; Hedayat, A.; Hipp, B.; Plachta, D. W.

2010-01-01

Cryocooler and passive insulation technology advances have substantially improved prospects for zero-boiloff cryogenic storage. Therefore, a cooperative effort by NASA s Ames Research Center, Glenn Research Center, and Marshall Space Flight Center (MSFC) was implemented to develop zero-boiloff concepts for in-space cryogenic storage. Described herein is one program element - a large-scale, zero-boiloff demonstration using the MSFC multipurpose hydrogen test bed (MHTB). A commercial cryocooler was interfaced with an existing MHTB spray bar mixer and insulation system in a manner that enabled a balance between incoming and extracted thermal energy.

LEGO-MM: LEarning structured model by probabilistic loGic Ontology tree for MultiMedia.

PubMed

Tang, Jinhui; Chang, Shiyu; Qi, Guo-Jun; Tian, Qi; Rui, Yong; Huang, Thomas S

2016-09-22

Recent advances in Multimedia ontology have resulted in a number of concept models, e.g., LSCOM and Mediamill 101, which are accessible and public to other researchers. However, most current research effort still focuses on building new concepts from scratch, very few work explores the appropriate method to construct new concepts upon the existing models already in the warehouse. To address this issue, we propose a new framework in this paper, termed LEGO1-MM, which can seamlessly integrate both the new target training examples and the existing primitive concept models to infer the more complex concept models. LEGOMM treats the primitive concept models as the lego toy to potentially construct an unlimited vocabulary of new concepts. Specifically, we first formulate the logic operations to be the lego connectors to combine existing concept models hierarchically in probabilistic logic ontology trees. Then, we incorporate new target training information simultaneously to efficiently disambiguate the underlying logic tree and correct the error propagation. Extensive experiments are conducted on a large vehicle domain data set from ImageNet. The results demonstrate that LEGO-MM has significantly superior performance over existing state-of-the-art methods, which build new concept models from scratch.

A quality-refinement process for medical imaging applications.

PubMed

Neuhaus, J; Maleike, D; Nolden, M; Kenngott, H-G; Meinzer, H-P; Wolf, I

2009-01-01

To introduce and evaluate a process for refinement of software quality that is suitable to research groups. In order to avoid constraining researchers too much, the quality improvement process has to be designed carefully. The scope of this paper is to present and evaluate a process to advance quality aspects of existing research prototypes in order to make them ready for initial clinical studies. The proposed process is tailored for research environments and therefore more lightweight than traditional quality management processes. Focus on quality criteria that are important at the given stage of the software life cycle. Usage of tools that automate aspects of the process is emphasized. To evaluate the additional effort that comes along with the process, it was exemplarily applied for eight prototypical software modules for medical image processing. The introduced process has been applied to improve the quality of all prototypes so that they could be successfully used in clinical studies. The quality refinement yielded an average of 13 person days of additional effort per project. Overall, 107 bugs were found and resolved by applying the process. Careful selection of quality criteria and the usage of automated process tools lead to a lightweight quality refinement process suitable for scientific research groups that can be applied to ensure a successful transfer of technical software prototypes into clinical research workflows.

Feasibility of using a knowledge-based system concept for in-flight primary flight display research

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.

1991-01-01

A study was conducted to determine the feasibility of using knowledge-based systems architectures for inflight research of primary flight display information management issues. The feasibility relied on the ability to integrate knowledge-based systems with existing onboard aircraft systems. And, given the hardware and software platforms available, the feasibility also depended on the ability to use interpreted LISP software with the real time operation of the primary flight display. In addition to evaluating these feasibility issues, the study determined whether the software engineering advantages of knowledge-based systems found for this application in the earlier workstation study extended to the inflight research environment. To study these issues, two integrated knowledge-based systems were designed to control the primary flight display according to pre-existing specifications of an ongoing primary flight display information management research effort. These two systems were implemented to assess the feasibility and software engineering issues listed. Flight test results were successful in showing the feasibility of using knowledge-based systems inflight with actual aircraft data.

Joint China-United States Report for Year 1 Insulation Materials and Systems Project Area Clean Energy Research Center Building Energy Efficiency (CERC-BEE)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stovall, Therese K; Biswas, Kaushik; Song, Bo

In November of 2009, the presidents of China and the U.S. announced the establishment of the Clean Energy Research Center (CERC). This broad research effort is co-funded by both countries and involves a large number of research centers and universities in both countries. One part of this program is focused on improving the energy efficiency of buildings. One portion of the CERC-BEE was focused on building insulation systems. The research objective of this effort was to Identify and investigate candidate high performance fire resistant building insulation technologies that meet the goal of building code compliance for exterior wall applications inmore » green buildings in multiple climate zones. A Joint Work Plan was established between researchers at the China Academy of Building Research and Oak Ridge National Laboratory. Efforts in the first year under this plan focused on information gathering. The objective of this research program is to reduce building energy use in China via improved building insulation technology. In cold regions in China, residents often use inefficient heating systems to provide a minimal comfort level within inefficient buildings. In warmer regions, air conditioning has not been commonly used. As living standards rise, energy consumption in these regions will increase dramatically unless significant improvements are made in building energy performance. Previous efforts that defined the current state of the built environment in China and in the U.S. will be used in this research. In countries around the world, building improvements have typically followed the implementation of more stringent building codes. There have been several changes in building codes in both the U.S. and China within the last few years. New U.S. building codes have increased the amount of wall insulation required in new buildings. New government statements from multiple agencies in China have recently changed the requirements for buildings in terms of energy efficiency and fire safety. A related issue is the degree to which new standards are adopted and enforced. In the U.S., standards are developed using a consensus process, and local government agencies are free to implement these standards or to ignore them. For example, some U.S. states are still using 2003 versions of the building efficiency standards. There is also a great variation in the degree to which the locally adopted standards are enforced in different U.S. cities and states. With a more central process in China, these issues are different, but possible impacts of variable enforcement efficacy may also exist. Therefore, current building codes in China will be compared to the current state of building fire-safety and energy-efficiency codes in the U.S. and areas for possible improvements in both countries will be explored. In particular, the focus of the applications in China will be on green buildings. The terminology of 'green buildings' has different meanings to different audiences. The U.S. research is interested in both new, green buildings, and on retrofitting existing inefficient buildings. An initial effort will be made to clarify the scope of the pertinent wall insulation systems for these applications.« less

Development of an inter-atomic potential for the Pd-H binary system.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zimmerman, Jonathan A.; Hoyt, Jeffrey John; Leonard, Francois Leonard

2007-09-01

Ongoing research at Sandia National Laboratories has been in the area of developing models and simulation methods that can be used to uncover and illuminate the material defects created during He bubble growth in aging bulk metal tritides. Previous efforts have used molecular dynamics calculations to examine the physical mechanisms by which growing He bubbles in a Pd metal lattice create material defects. However, these efforts focused only on the growth of He bubbles in pure Pd and not on bubble growth in the material of interest, palladium tritide (PdT), or its non-radioactive isotope palladium hydride (PdH). The reason formore » this is that existing inter-atomic potentials do not adequately describe the thermodynamics of the Pd-H system, which includes a miscibility gap that leads to phase separation of the dilute (alpha) and concentrated (beta) alloys of H in Pd at room temperature. This document will report the results of research to either find or develop inter-atomic potentials for the Pd-H and Pd-T systems, including our efforts to use experimental data and density functional theory calculations to create an inter-atomic potential for this unique metal alloy system.« less

Astrobiology: A Roadmap for Charting Life in the Universe

NASA Technical Reports Server (NTRS)

DesMarais, David J.; DeVincezi, D. (Technical Monitor)

2002-01-01

Astrobiology is the study of the origin, evolution and distribution of life in the universe. It provides a biological perspective to many areas of NASA research. It links such endeavors as the search for habitable planets, exploration missions to Mars and the outer Solar System, efforts to understand the origins and early evolution of life, and charting the potential of life to adapt to future challenges, both on Earth and in space. Astrobiology addresses the following three basic questions, which have been asked in some form for generations. How does life begin and evolve? Does life exist elsewhere in the universe? What is future of life on Earth and beyond? The NASA Astrobiology Roadmap provides guidance for research and technology development across several NASA Enterprises: Space Science, Earth Science, and the Human Exploration and Development of Space. The Roadmap is formulated in terms of eight Science Goals that outline key domains of investigation that might require perhaps decades of effort to consolidate. For each of these goals, Science Objectives outline more specific high priority near-term efforts for the next three to five years. These twenty objectives will be integrated with NASA strategic planning.

Big Data and Population Health: Focusing on the Health Impacts of the Social, Physical, and Economic Environment.

PubMed

Hu, Howard; Galea, Sandro; Rosella, Laura; Henry, David

2017-11-01

We are at the dawn of a data deluge in health that carries extraordinary promise for improving the health of populations. However, current associated efforts, which generally center on the 'precision medicine' agenda, may well fall short in terms of its overall impact. The main challenges, it is argued, are less technical than the following: (1) identifying the data that matter most; (2) ensuring that we make better use of existing data; and (3) extending our efforts from the individual to the population by exploiting new, complex, and sometimes unstructured, data sources. Advances in Epidemiology have shown that policies, features of institutions, characteristics of communities, living and environmental conditions, and social relationships all contribute, together with individual behaviors and factors such as poverty and race, to the production of health. Examples are discussed, leading to recommendations that focus on core priorities for data linkage, including those relating to marginalized populations, better data on socioeconomic status, micro- and macro-environments, collaborating with researchers in the fields of education, environment, and social sciences to ensure the validity and accuracy of multilevel data, aligning research aims with policy decisions that must be made, and heightening efforts to protect privacy.

Communication Competence, Psychological Well-being, and the Mediating Role of Coping Efforts among Women with Breast Cancer: Cross-sectional and Longitudinal Evidence

PubMed Central

Shim, Minsun; Mercer Kollar, Laura M.; Roberts, Linda; Gustafson, David

2015-01-01

Despite existing research identifying psychological benefits of patients’ interpersonal competence in various contexts, little longitudinal research has addressed underlying mechanism(s). To address this limitation, we examined both the cross-sectional and longitudinal associations between cancer patients’ communication competence in close relationships and psychological well-being, as well as the mediating role of coping efforts. Data came from a larger project with women with breast cancer (N = 661), recruited from April 2005 to May 2007 at three large university-affiliated cancer centers in the U.S. to study the effects of an Internet-based system providing patients and families with a range of services. The present study focused on survey data at baseline, 6 weeks, and 12 weeks after the intervention (controlling for the possible effects of the intervention). Results from both cross-sectional and longitudinal analyses indicated that competence in open communication between patients and their close support persons had a positive association with patients’ psychological well-being and that approach coping efforts partially mediated this association. We discussed the implications and limitations of the study. PMID:25793748

Ocean acidification postcards

USGS Publications Warehouse

Schreppel, Heather A.; Cimitile, Matthew J.

2011-01-01

The U.S. Geological Survey (USGS) is conducting research on ocean acidification in polar, temperate, subtropical, and tropical regions including the Arctic, West Florida Shelf, and the Caribbean. Project activities include field assessment, experimental laboratory studies, and evaluation of existing data. The USGS is participating in international and interagency working groups to develop research strategies to increase understanding of the global implications of ocean acidification. Research strategies include new approaches for seawater chemistry observation and modeling, assessment of physiological effects on organisms, changes in marine ecosystem structure, new technologies, and information resources. These postcards highlight ongoing USGS research efforts in ocean acidification and carbon cycling in marine and coastal ecosystems in three different regions: polar, temperate, and tropical. To learn more about ocean acidification visit: http://coastal.er.usgs.gov/ocean-acidification/.

LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bookless, W.

This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

Recruitment of multiple stakeholders to health services research: lessons from the front lines.

PubMed

Kho, Michelle E; Rawski, Ellen; Makarski, Julie; Brouwers, Melissa C

2010-05-13

Self-administered surveys are an essential methodological tool for health services and knowledge translation research, and engaging end-users of the research is critical. However, few documented accounts of the efforts invested in recruitment of multiple different stakeholders to one health services research study exist. Here, we highlight the challenges of recruiting key stakeholders (policy-makers, clinicians, guideline developers) to a Canadian Institutes of Health Research (CIHR) funded health services research (HSR) study aimed to develop an updated and refined version of a guideline appraisal tool, the AGREE. Using evidence-based methods of recruitment, our goal was to recruit 192 individuals: 80 international guideline developers, 80 Canadian clinicians and 32 Canadian policy/decision-makers. We calculated the participation rate and the recruitment efficiency. We mailed 873 invitation letters. Of 838 approached, our participation rate was 29%(240) and recruitment efficiency, 19%(156). One policy-maker manager did not allow policy staff to participate in the study. Based on the results from this study, we suggest that future studies aiming to engage similar stakeholders in HSR over sample by at least 5 times to achieve their target sample size and allow for participant withdrawals. We need continued efforts to communicate the value of research between researchers and end-users of research (policy-makers, clinicians, and other researchers), integration of participatory research strategies, and promotion of the value of end-user involvement in research. Future research to understand methods of improving recruitment efficiency and engaging key stakeholders in HSR is warranted.

The Global Evidence Mapping Initiative: scoping research in broad topic areas.

PubMed

Bragge, Peter; Clavisi, Ornella; Turner, Tari; Tavender, Emma; Collie, Alex; Gruen, Russell L

2011-06-17

Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence gaps, and may guide future research efforts. The Global Evidence Mapping (GEM) Initiative was established in 2007 to create evidence maps providing an overview of existing research in Traumatic Brain Injury (TBI) and Spinal Cord Injury (SCI). The GEM evidence mapping method involved three core tasks:1. Setting the boundaries and context of the map: Definitions for the fields of TBI and SCI were clarified, the prehospital, acute inhospital and rehabilitation phases of care were delineated and relevant stakeholders (patients, carers, clinicians, researchers and policymakers) who could contribute to the mapping were identified. Researchable clinical questions were developed through consultation with key stakeholders and a broad literature search. 2. Searching for and selection of relevant studies: Evidence search and selection involved development of specific search strategies, development of inclusion and exclusion criteria, searching of relevant databases and independent screening and selection by two researchers. 3. Reporting on yield and study characteristics: Data extraction was performed at two levels - 'interventions and study design' and 'detailed study characteristics'. The evidence map and commentary reflected the depth of data extraction. One hundred and twenty-nine researchable clinical questions in TBI and SCI were identified. These questions were then prioritised into high (n = 60) and low (n = 69) importance by the stakeholders involved in question development. Since 2007, 58 263 abstracts have been screened, 3 731 full text articles have been reviewed and 1 644 relevant neurotrauma publications have been mapped, covering fifty-three high priority questions. GEM Initiative evidence maps have a broad range of potential end-users including funding agencies, researchers and clinicians. Evidence mapping is at least as resource-intensive as systematic reviewing. The GEM Initiative has made advancements in evidence mapping, most notably in the area of question development and prioritisation. Evidence mapping complements other review methods for describing existing research, informing future research efforts, and addressing evidence gaps.

The Global Evidence Mapping Initiative: Scoping research in broad topic areas

PubMed Central

2011-01-01

Background Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence gaps, and may guide future research efforts. The Global Evidence Mapping (GEM) Initiative was established in 2007 to create evidence maps providing an overview of existing research in Traumatic Brain Injury (TBI) and Spinal Cord Injury (SCI). Methods The GEM evidence mapping method involved three core tasks: 1. Setting the boundaries and context of the map: Definitions for the fields of TBI and SCI were clarified, the prehospital, acute inhospital and rehabilitation phases of care were delineated and relevant stakeholders (patients, carers, clinicians, researchers and policymakers) who could contribute to the mapping were identified. Researchable clinical questions were developed through consultation with key stakeholders and a broad literature search. 2. Searching for and selection of relevant studies: Evidence search and selection involved development of specific search strategies, development of inclusion and exclusion criteria, searching of relevant databases and independent screening and selection by two researchers. 3. Reporting on yield and study characteristics: Data extraction was performed at two levels - 'interventions and study design' and 'detailed study characteristics'. The evidence map and commentary reflected the depth of data extraction. Results One hundred and twenty-nine researchable clinical questions in TBI and SCI were identified. These questions were then prioritised into high (n = 60) and low (n = 69) importance by the stakeholders involved in question development. Since 2007, 58 263 abstracts have been screened, 3 731 full text articles have been reviewed and 1 644 relevant neurotrauma publications have been mapped, covering fifty-three high priority questions. Conclusions GEM Initiative evidence maps have a broad range of potential end-users including funding agencies, researchers and clinicians. Evidence mapping is at least as resource-intensive as systematic reviewing. The GEM Initiative has made advancements in evidence mapping, most notably in the area of question development and prioritisation. Evidence mapping complements other review methods for describing existing research, informing future research efforts, and addressing evidence gaps. PMID:21682870

Evaluation of Colorado Learning Attitudes about Science Survey

NASA Astrophysics Data System (ADS)

Douglas, K. A.; Yale, M. S.; Bennett, D. E.; Haugan, M. P.; Bryan, L. A.

2014-12-01

The Colorado Learning Attitudes about Science Survey (CLASS) is a widely used instrument designed to measure student attitudes toward physics and learning physics. Previous research revealed a fairly complex factor structure. In this study, exploratory and confirmatory factor analyses were conducted on data from an undergraduate introductory physics course (n =3844 ) to determine whether a more parsimonious factor structure exists. Exploratory factor analysis results indicate that many of the items from the original CLASS have poor psychometric properties and could not be used in a revised factor structure. The cross validation showed acceptable fit statistics for a three factor model found in the exploratory factor analysis. This research suggests that a more optimum measurement of students' attitudes about physics and learning physics is obtained with a 15-item instrument, which describes the factors of personal application, personal effort, and problem solving. The proposed revised version of the CLASS offers researchers the opportunity to test a shortened version of the instrument that may be able to provide information about students' attitudes in the areas of personal application of physics, personal effort in a physics course, and approaches to problem solving.

Getting ready for the Human Phenome Project: the 2012 forum of the Human Variome Project.

PubMed

Oetting, William S; Robinson, Peter N; Greenblatt, Marc S; Cotton, Richard G; Beck, Tim; Carey, John C; Doelken, Sandra C; Girdea, Marta; Groza, Tudor; Hamilton, Carol M; Hamosh, Ada; Kerner, Berit; MacArthur, Jacqueline A L; Maglott, Donna R; Mons, Barend; Rehm, Heidi L; Schofield, Paul N; Searle, Beverly A; Smedley, Damian; Smith, Cynthia L; Bernstein, Inge Thomsen; Zankl, Andreas; Zhao, Eric Y

2013-04-01

A forum of the Human Variome Project (HVP) was held as a satellite to the 2012 Annual Meeting of the American Society of Human Genetics in San Francisco, California. The theme of this meeting was "Getting Ready for the Human Phenome Project." Understanding the genetic contribution to both rare single-gene "Mendelian" disorders and more complex common diseases will require integration of research efforts among many fields and better defined phenotypes. The HVP is dedicated to bringing together researchers and research populations throughout the world to provide the resources to investigate the impact of genetic variation on disease. To this end, there needs to be a greater sharing of phenotype and genotype data. For this to occur, many databases that currently exist will need to become interoperable to allow for the combining of cohorts with similar phenotypes to increase statistical power for studies attempting to identify novel disease genes or causative genetic variants. Improved systems and tools that enhance the collection of phenotype data from clinicians are urgently needed. This meeting begins the HVP's effort toward this important goal. © 2013 Wiley Periodicals, Inc.

High-resolution geophysical data collected aboard the U.S. Geological Survey research vessel Rafael to supplement existing datasets from Buzzards Bay and Vineyard Sound, Massachusetts

USGS Publications Warehouse

Pendleton, Elizabeth A.; Andrews, Brian D.; Danforth, William W.; Foster, David S.

2014-01-01

Geophysical and geospatial data were collected in Buzzards Bay, in the shallow-water areas of Vineyard Sound, and in the nearshore areas off the eastern Elizabeth Islands and northern coast of Martha's Vineyard, Massachusetts, on the U.S. Geological Survey research vessel Rafael between 2007 and 2011, in a collaborative effort between the U.S. Geological Survey and the Massachusetts Office of Coastal Zone Management. This report describes results of this collaborative effort, which include mapping the geology of the inner shelf zone of the Elizabeth Islands and the sand shoals of Vineyard Sound and studying geologic processes that contribute to the evolution of this area. Data collected during these surveys include: bathymetry, acoustic backscatter, seismic-reflection profiles, sound velocity profiles, and navigation. The long-term goals of this project are (1) to provide high-resolution geophysical data that will support research on the influence of sea-level change and sediment supply on coastal evolution and (2) to inventory subtidal marine habitats and their distribution within the coastal zone of Massachusetts.

Libraries and Librarians: Key Partners for Progress in Health Literacy Research and Practice.

PubMed

Whitney, Wanda; Keselman, Alla; Humphreys, Betsy

2017-01-01

The field of librarianship has a history of involvement in patient education, general literacy and information literacy efforts. This history and prominent placement in communities make libraries and librarians an excellent resource in advancing health literacy practice and research. This chapter provides an overview of health literacy and health information literacy efforts in US libraries over the past two decades. The chapter begins with the description of the role of the US National Library of Medicine in developing resources, programs, and partnerships serving health information needs of the public. It then overviews special training programs for increasing librarians' expertise with health information and health literacy support. The narrative also presents different models of health information outreach programs in diverse communities, focusing on serving special populations that may suffer from health disparities. The second half of the chapter describes libraries' and librarians' health information response to continuously evolving contexts, mediums, and requirements. One subsection describes librarians' outreach effort with cutting-edge technologies, such as virtual worlds and gaming. Another focuses on supporting patients' information needs in clinical settings. Two more describe how libraries meet patrons' health information needs in the context of disaster preparedness and health insurance market place sign-up. While presenting the information, to the extent possible, the chapter draws upon research and evaluation of the effectiveness of different types of programs. It also discusses enablers of successes, limitations of the existing data, and directions for future research.

Libraries and Librarians: Key Partners for Progress in Health Literacy Research and Practice

PubMed Central

WHITNEY, Wanda; KESELMAN, Alla; HUMPHREYS, Betsy

2017-01-01

The field of librarianship has a history of involvement in patient education, general literacy and information literacy efforts. This history and prominent placement in communities make libraries and librarians an excellent resource in advancing health literacy practice and research. This chapter provides an overview of health literacy and health information literacy efforts in US libraries over the past two decades. The chapter begins with the description of the role of the US National Library of Medicine in developing resources, programs, and partnerships serving health information needs of the public. It then overviews special training programs for increasing librarians’ expertise with health information and health literacy support. The narrative also presents different models of health information outreach programs in diverse communities, focusing on serving special populations that may suffer from health disparities. The second half of the chapter describes libraries’ and librarians’ health information response to continuously evolving contexts, mediums, and requirements. One subsection describes librarians’ outreach effort with cutting-edge technologies, such as virtual worlds and gaming. Another focuses on supporting patients’ information needs in clinical settings. Two more describe how libraries meet patrons’ health information needs in the context of disaster preparedness and health insurance market place sign-up. While presenting the information, to the extent possible, the chapter draws upon research and evaluation of the effectiveness of different types of programs. It also discusses enablers of successes, limitations of the existing data, and directions for future research. PMID:28972531

A Nonparametric, Multiple Imputation-Based Method for the Retrospective Integration of Data Sets.

PubMed

Carrig, Madeline M; Manrique-Vallier, Daniel; Ranby, Krista W; Reiter, Jerome P; Hoyle, Rick H

2015-01-01

Complex research questions often cannot be addressed adequately with a single data set. One sensible alternative to the high cost and effort associated with the creation of large new data sets is to combine existing data sets containing variables related to the constructs of interest. The goal of the present research was to develop a flexible, broadly applicable approach to the integration of disparate data sets that is based on nonparametric multiple imputation and the collection of data from a convenient, de novo calibration sample. We demonstrate proof of concept for the approach by integrating three existing data sets containing items related to the extent of problematic alcohol use and associations with deviant peers. We discuss both necessary conditions for the approach to work well and potential strengths and weaknesses of the method compared to other data set integration approaches.

Brand communities embedded in social networks.

PubMed

Zaglia, Melanie E

2013-02-01

Brand communities represent highly valuable marketing, innovation management, and customer relationship management tools. However, applying successful marketing strategies today, and in the future, also means exploring and seizing the unprecedented opportunities of social network environments. This study combines these two social phenomena which have largely been researched separately, and aims to investigate the existence, functionality and different types of brand communities within social networks. The netnographic approach yields strong evidence of this existence; leading to a better understanding of such embedded brand communities, their peculiarities, and motivational drivers for participation; therefore the findings contribute to theory by combining two separate research streams. Due to the advantages of social networks, brand management is now able to implement brand communities with less time and financial effort; however, choosing the appropriate brand community type, cultivating consumers' interaction, and staying tuned to this social engagement are critical factors to gain anticipated brand outcomes.

Integrating existing software toolkits into VO system

NASA Astrophysics Data System (ADS)

Cui, Chenzhou; Zhao, Yong-Heng; Wang, Xiaoqian; Sang, Jian; Luo, Ze

2004-09-01

Virtual Observatory (VO) is a collection of interoperating data archives and software tools. Taking advantages of the latest information technologies, it aims to provide a data-intensively online research environment for astronomers all around the world. A large number of high-qualified astronomical software packages and libraries are powerful and easy of use, and have been widely used by astronomers for many years. Integrating those toolkits into the VO system is a necessary and important task for the VO developers. VO architecture greatly depends on Grid and Web services, consequently the general VO integration route is "Java Ready - Grid Ready - VO Ready". In the paper, we discuss the importance of VO integration for existing toolkits and discuss the possible solutions. We introduce two efforts in the field from China-VO project, "gImageMagick" and "Galactic abundance gradients statistical research under grid environment". We also discuss what additional work should be done to convert Grid service to VO service.

Benchmarking In-Flight Icing Detection Products for Future Upgrades

NASA Technical Reports Server (NTRS)

Politovich, M. K.; Minnis, P.; Johnson, D. B.; Wolff, C. A.; Chapman, M.; Heck, P. W.; Haggerty, J. A.

2004-01-01

This paper summarizes the results of a benchmarking exercise conducted as part of the NASA supported Advanced Satellite Aviation-Weather Products (ASAP) Program. The goal of ASAP is to increase and optimize the use of satellite data sets within the existing FAA Aviation Weather Research Program (AWRP) Product Development Team (PDT) structure and to transfer advanced satellite expertise to the PDTs. Currently, ASAP fosters collaborative efforts between NASA Laboratories, the University of Wisconsin Cooperative Institute for Meteorological Satellite Studies (UW-CIMSS), the University of Alabama in Huntsville (UAH), and the AWRP PDTs. This collaboration involves the testing and evaluation of existing satellite algorithms developed or proposed by AWRP teams, the introduction of new techniques and data sets to the PDTs from the satellite community, and enhanced access to new satellite data sets available through CIMSS and NASA Langley Research Center for evaluation and testing.

Engineering Effort Needed to Design Spacecraft with Radiation Constraints

NASA Technical Reports Server (NTRS)

Singleterry, Robert C., Jr.

2005-01-01

A roadmap is articulated that describes what is needed to allow designers, to include researchers, management, and engineers, to investigate, design, build, test, and fly spacecraft that meet the mission requirements yet, be as low cost as possible. This roadmap describes seven levels of tool fidelity and application: 1) Mission Speculation, 2) Management Overview, 3) Mission Design, 4) Detailed Design, 5) Simulation and Training, 6) Operations, and 7) Research. The interfaces and output are described in top-level detail along with the transport engines needed, and deficiencies are noted. This roadmap, if implemented, will allow Multidisciplinary Optimization (MDO) ideas to incorporate radiation concerns. Also, as NASA moves towards Simulation Based Acquisition (SBA), these tools will facilitate the appropriate spending of government money. Most of the tools needed to serve these levels do not exist or exist in pieces and need to be integrated to create the tool.

Brand communities embedded in social networks☆

PubMed Central

Zaglia, Melanie E.

2013-01-01

Brand communities represent highly valuable marketing, innovation management, and customer relationship management tools. However, applying successful marketing strategies today, and in the future, also means exploring and seizing the unprecedented opportunities of social network environments. This study combines these two social phenomena which have largely been researched separately, and aims to investigate the existence, functionality and different types of brand communities within social networks. The netnographic approach yields strong evidence of this existence; leading to a better understanding of such embedded brand communities, their peculiarities, and motivational drivers for participation; therefore the findings contribute to theory by combining two separate research streams. Due to the advantages of social networks, brand management is now able to implement brand communities with less time and financial effort; however, choosing the appropriate brand community type, cultivating consumers’ interaction, and staying tuned to this social engagement are critical factors to gain anticipated brand outcomes. PMID:23564989

A Nonparametric, Multiple Imputation-Based Method for the Retrospective Integration of Data Sets

PubMed Central

Carrig, Madeline M.; Manrique-Vallier, Daniel; Ranby, Krista W.; Reiter, Jerome P.; Hoyle, Rick H.

2015-01-01

Complex research questions often cannot be addressed adequately with a single data set. One sensible alternative to the high cost and effort associated with the creation of large new data sets is to combine existing data sets containing variables related to the constructs of interest. The goal of the present research was to develop a flexible, broadly applicable approach to the integration of disparate data sets that is based on nonparametric multiple imputation and the collection of data from a convenient, de novo calibration sample. We demonstrate proof of concept for the approach by integrating three existing data sets containing items related to the extent of problematic alcohol use and associations with deviant peers. We discuss both necessary conditions for the approach to work well and potential strengths and weaknesses of the method compared to other data set integration approaches. PMID:26257437

Multilingual Sentiment Analysis: State of the Art and Independent Comparison of Techniques.

PubMed

Dashtipour, Kia; Poria, Soujanya; Hussain, Amir; Cambria, Erik; Hawalah, Ahmad Y A; Gelbukh, Alexander; Zhou, Qiang

With the advent of Internet, people actively express their opinions about products, services, events, political parties, etc., in social media, blogs, and website comments. The amount of research work on sentiment analysis is growing explosively. However, the majority of research efforts are devoted to English-language data, while a great share of information is available in other languages. We present a state-of-the-art review on multilingual sentiment analysis. More importantly, we compare our own implementation of existing approaches on common data. Precision observed in our experiments is typically lower than the one reported by the original authors, which we attribute to the lack of detail in the original presentation of those approaches. Thus, we compare the existing works by what they really offer to the reader, including whether they allow for accurate implementation and for reliable reproduction of the reported results.

A Survey of Keystroke Dynamics Biometrics

PubMed Central

Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions. PMID:24298216

MEASURING COERCION TO PARTICIPATE IN RESEARCH WITHIN A DOUBLY VULNERABLE POPULATION: INITIAL DEVELOPMENT OF THE COERCION ASSESSMENT SCALE

PubMed Central

Dugosh, Karen Leggett; Festinger, David S.; Croft, Jason R.; Marlowe, Douglas B.

2011-01-01

Despite many efforts aimed to ensure that research participation is autonomous and not coerced, there exists no reliable and valid measure of perceived coercion for the doubly vulnerable population of substance-abusing offenders. The current study describes the development and initial validation of an instrument measuring perceived coercion to participate in research among substance-abusing offenders. The results indicated that a substantial number of individuals report feeling coerced to participate in the study. In addition, the instrument has adequate levels of internal consistency, a one-dimensional factor structure, and evidence of discriminative validity. This study provides initial support for the instrument’s validity and clinical utility. PMID:20235867

Aeroelastic modeling for the FIT (Functional Integration Technology) team F/A-18 simulation

NASA Technical Reports Server (NTRS)

Zeiler, Thomas A.; Wieseman, Carol D.

1989-01-01

As part of Langley Research Center's commitment to developing multidisciplinary integration methods to improve aerospace systems, the Functional Integration Technology (FIT) team was established to perform dynamics integration research using an existing aircraft configuration, the F/A-18. An essential part of this effort has been the development of a comprehensive simulation modeling capability that includes structural, control, and propulsion dynamics as well as steady and unsteady aerodynamics. The structural and unsteady aerodynamics contributions come from an aeroelastic mode. Some details of the aeroelastic modeling done for the Functional Integration Technology (FIT) team research are presented. Particular attention is given to work done in the area of correction factors to unsteady aerodynamics data.

Breast and cervical cancer control among Pacific Islander and Southeast Asian Women: participatory action research strategies for baseline data collection in California.

PubMed

Kagawa-Singer, Marjorie; Park Tanjasiri, Sora; Lee, Susan W; Foo, Mary Anne; Ngoc Nguyen, Tu-Uyen; Tran, Jacqueline H; Valdez, Annalyn

2006-01-01

No data exists on the breast and cervical cancer screening practices among Cambodian, Laotian, Thai, and Tongan women. In this article, we describe the efforts required to conduct a baseline survey among these non-English-speaking women using the participatory action research (PAR) approach. We tailored small population sampling techniques to each of the populations in partnership with Community Health Outreach workers. A total of 1825 surveys were successfully conducted in 8 communities. PAR and the culturally based techniques used to conduct the survey proved successful in maintaining scientific rigor, developing true community-researcher partnership, and achieving over 99% participation.

Prospects for the Comparative Study of International Migration using quasi-longitudinal micro-data

PubMed Central

Liu, Mao-Mei; Creighton, Mathew J.; Riosmena, Fernando; Baizán Mun͂oz, Pau

2017-01-01

BACKGROUND Longitudinal micro-level data about international migration behavior are notoriously difficult to collect, but data collection efforts have become more frequent in recent years. Comparative research of the patterns and processes of international migration, however, remains quite rare, especially that which compares across regions. OBJECTIVE We highlight the promises and difficulties of comparative international migration research, by offering a detailed comparison of two prominent data collection efforts. METHODS We systematically review existing sources of longitudinal and quasi-longitudinal individual-level and household-level data of international migration. We then compare two widely-used data sources: the Mexican Migration Project (MMP) and the Migration between Africa and Europe project (MAFE). RESULTS Data collection efforts are increasingly diverse, yet public accessibility of data remains limited. Also, comparability of data collected across settings can be complicated. In our MMP-MAFE analysis, we show some ways in which comparability can be achieved. CONCLUSIONS A primary roadblock to international comparative research is that, with some exceptions, the public accessibility of data remains low. Even when data is public and surveys are modeled after one another, comparability is not easy due to necessary trade-offs in adapting surveys to local settings and to developments in the field. CONTRIBUTION We demonstrate that, despite great strides in collecting quasi-longitudinal data of international migration, data accessibility still hinders the study of migration. With regards to comparability, our article provides important lessons for future data collection and analysis efforts that could improve comparability and thus advance understanding of the complex dynamics of international migration. PMID:29276429

Institutional Nitrogen Footprint: A Case Study at Oregon State ...

EPA Pesticide Factsheets

Many institutions of higher education are measuring and consciously managing their impact on the environment, using metrics of energy use, recycling, alternative transportation or local foods. While the carbon footprint is a more widely known metric of sustainability, the nitrogen footprint is also an important measure of human environmental impact that comes from food, energy, transportation and waste demands of a university. Oregon State University is a large, western land-grant university that has supported a Sustainability Office for more than 10 years, and joined the institutional Nitrogen Footprint Network in 2015. This poster presentation will demonstrate the Nitrogen Footprint Tool calculations for a large land-grant institution using existing data. Goals to reduce nitrogen will be explored in relation to existing efforts within the university that aim to reduce their carbon footprint, support alternative transportation, reduce waste and increase local foods. EPA's Sustainable and Healthy Communities Research Program has been working with the University of Virginia to grow the Nitrogen Footprint Tool (NFT) network from one institution to over 16 institutions since 2014. This poster will present the nitrogen footprint results from Oregon State University. The university has been actively involved in sustainability efforts for many years, and this presentation will share how much of the data that OSU collects for their existing sustainability metrics

Cartographic production for the Florida Shelf Habitat (FLaSH) map study: generation of surface grids, contours, and KMZ files

USGS Publications Warehouse

Robbins, Lisa L.; Hansen, Mark; Raabe, Ellen; Knorr, Paul O.; Browne, Joseph

2007-01-01

The Florida shelf represents a finite source of economic resources, including commercial and recreational fisheries, tourism, recreation, sand and gravel resources, phosphate, and freshwater reserves. Yet the basic information needed to locate resources, or to interpret and utilize existing data, comes from many sources, dates, and formats. A multi-agency effort is underway to coordinate and prioritize the compilation of suitable datasets for an integrated information system of Florida’s coastal and ocean resources. This report and the associated data files represent part of the effort to make data accessible and useable with computer-mapping systems, web-based technologies, and user-friendly visualization tools. Among the datasets compiled and developed are seafloor imagery, marine sediment data, and existing bathymetric data. A U.S. Geological Survey-sponsored workshop in January 2007 resulted in the establishment of mapping priorities for the state. Bathymetry was identified as a common priority among agencies and researchers. State-of-the-art computer-mapping techniques and data-processing tools were used to develop shelf-wide raster and vector data layers. Florida Shelf Habitat (FLaSH) Mapping Project (http://coastal.er.usgs.gov/flash) endeavors to locate available data, identify data gaps, synthesize existing information, and expand our understanding of geologic processes in our dynamic coastal and marine systems.

Effort-Based Decision Making: A Novel Approach for Assessing Motivation in Schizophrenia.

PubMed

Green, Michael F; Horan, William P; Barch, Deanna M; Gold, James M

2015-09-01

Because negative symptoms, including motivational deficits, are a critical unmet need in schizophrenia, there are many ongoing efforts to develop new pharmacological and psychosocial interventions for these impairments. A common challenge of these studies involves how to evaluate and select optimal endpoints. Currently, all studies of negative symptoms in schizophrenia depend on ratings from clinician-conducted interviews. Effort-based decision-making tasks may provide a more objective, and perhaps more sensitive, endpoint for trials of motivational negative symptoms. These tasks assess how much effort a person is willing to exert for a given level of reward. This area has been well-studied with animal models of effort and motivation, and effort-based decision-making tasks have been adapted for use in humans. Very recently, several studies have examined physical and cognitive types of effort-based decision-making tasks in cross-sectional studies of schizophrenia, providing evidence for effort-related impairment in this illness. This article covers the theoretical background on effort-based decision-making tasks to provide a context for the subsequent articles in this theme section. In addition, we review the existing literature of studies using these tasks in schizophrenia, consider some practical challenges in adapting them for use in clinical trials in schizophrenia, and discuss interpretive challenges that are central to these types of tasks. © The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

The ACI-REF Program: Empowering Prospective Computational Researchers

NASA Astrophysics Data System (ADS)

Cuma, M.; Cardoen, W.; Collier, G.; Freeman, R. M., Jr.; Kitzmiller, A.; Michael, L.; Nomura, K. I.; Orendt, A.; Tanner, L.

2014-12-01

The ACI-REF program, Advanced Cyberinfrastructure - Research and Education Facilitation, represents a consortium of academic institutions seeking to further advance the capabilities of their respective campus research communities through an extension of the personal connections and educational activities that underlie the unique and often specialized cyberinfrastructure at each institution. This consortium currently includes Clemson University, Harvard University, University of Hawai'i, University of Southern California, University of Utah, and University of Wisconsin. Working together in a coordinated effort, the consortium is dedicated to the adoption of models and strategies which leverage the expertise and experience of its members with a goal of maximizing the impact of each institution's investment in research computing. The ACI-REFs (facilitators) are tasked with making connections and building bridges between the local campus researchers and the many different providers of campus, commercial, and national computing resources. Through these bridges, ACI-REFs assist researchers from all disciplines in understanding their computing and data needs and in mapping these needs to existing capabilities or providing assistance with development of these capabilities. From the Earth sciences perspective, we will give examples of how this assistance improved methods and workflows in geophysics, geography and atmospheric sciences. We anticipate that this effort will expand the number of researchers who become self-sufficient users of advanced computing resources, allowing them to focus on making research discoveries in a more timely and efficient manner.

Monitoring the tobacco use epidemic IV. The vector: Tobacco industry data sources and recommendations for research and evaluation.

PubMed

Cruz, Tess Boley

2009-01-01

This Vector paper (IV of V on monitoring the tobacco use epidemic) presents the data sources and methods that can be used to monitor tobacco marketing and makes recommendations for creating a national surveillance system. In 2002, the Vector Work Group of the National Tobacco Monitoring, Research and Evaluation Workshop identified priority indicators of tobacco marketing: tobacco brand pricing strategies, retail environment advertising and promotional allowances, gray market or smuggling activities, lobbying, direct mail marketing, tobacco brand placements in films, Internet promotions, and sponsorship at bars and events. This paper reviews and identifies data sources and gaps for these priority indicators and for 12 other indicators of interest. There are 38 commercial data sites and Internet sources, as well as individual research efforts that address the priority indicators. These sources are not integrated, often costly, and limited in standardization. Tobacco marketing could be more effectively monitored with the development of a national research network. Surveillance of the tobacco industry's methods to push tobacco and pull consumers can help the public health community identify new markets and campaigns, justify and tailor effective tobacco control strategies, and evaluate existing counter-marketing efforts.

Validation plays the role of a "bridge" in connecting remote sensing research and applications

NASA Astrophysics Data System (ADS)

Wang, Zhiqiang; Deng, Ying; Fan, Yida

2018-07-01

Remote sensing products contribute to improving earth observations over space and time. Uncertainties exist in products of different levels; thus, validation of these products before and during their applications is critical. This study discusses the meaning of validation in depth and proposes a new definition of reliability for use with such products. In this context, validation should include three aspects: a description of the relevant uncertainties, quantitative measurement results and a qualitative judgment that considers the needs of users. A literature overview is then presented evidencing improvements in the concepts associated with validation. It shows that the root mean squared error (RMSE) is widely used to express accuracy; increasing numbers of remote sensing products have been validated; research institutes contribute most validation efforts; and sufficient validation studies encourage the application of remote sensing products. Validation plays a connecting role in the distribution and application of remote sensing products. Validation connects simple remote sensing subjects with other disciplines, and it connects primary research with practical applications. Based on the above findings, it is suggested that validation efforts that include wider cooperation among research institutes and full consideration of the needs of users should be promoted.

Military efforts in nanosensors, 3D printing, and imaging detection

NASA Astrophysics Data System (ADS)

Edwards, Eugene; Booth, Janice C.; Roberts, J. Keith; Brantley, Christina L.; Crutcher, Sihon H.; Whitley, Michael; Kranz, Michael; Seif, Mohamed; Ruffin, Paul

2017-04-01

A team of researchers and support organizations, affiliated with the Army Aviation and Missile Research, Development, and Engineering Center (AMRDEC), has initiated multidiscipline efforts to develop nano-based structures and components for advanced weaponry, aviation, and autonomous air/ground systems applications. The main objective of this research is to exploit unique phenomena for the development of novel technology to enhance warfighter capabilities and produce precision weaponry. The key technology areas that the authors are exploring include nano-based sensors, analysis of 3D printing constituents, and nano-based components for imaging detection. By integrating nano-based devices, structures, and materials into weaponry, the Army can revolutionize existing (and future) weaponry systems by significantly reducing the size, weight, and cost. The major research thrust areas include the development of carbon nanotube sensors to detect rocket motor off-gassing; the application of current methodologies to assess materials used for 3D printing; and the assessment of components to improve imaging seekers. The status of current activities, associated with these key areas and their implementation into AMRDEC's research, is outlined in this paper. Section #2 outlines output data, graphs, and overall evaluations of carbon nanotube sensors placed on a 16 element chip and exposed to various environmental conditions. Section #3 summarizes the experimental results of testing various materials and resulting components that are supplementary to additive manufacturing/fused deposition modeling (FDM). Section #4 recapitulates a preliminary assessment of the optical and electromechanical components of seekers in an effort to propose components and materials that can work more effectively.

Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance

PubMed Central

2012-01-01

Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public health response. A comprehensive effort, involving the collaboration of 188 scientists (>85% from P.R. China) from 48 different institutions and universities (80% from P.R. China), covers this collection of 29 articles published in Parasites & Vectors. The research mainly stems from a research project entitled “Surveillance and diagnostic tools for major parasitic diseases in P.R. China” (grant no. 2008ZX10004-011) and highlights the frontiers of research in parasitology. The majority of articles in this thematic series deals with the most important parasitic diseases in P.R. China, emphasizing Schistosoma japonicum, Plasmodium vivax and Clonorchis sinensis plus some parasites of emerging importance such as Angiostrongylus cantonensis. Significant achievements have been made through the collaborative research programme in the following three fields: (i) development of strategies for the national control programme; (ii) updating the surveillance data of parasitic infections both in human and animals; and (iii) improvement of existing, and development of novel, diagnostic tools to detect parasitic infections. The progress is considerable and warrants broad validation efforts. Combined with the development of improved tools for diagnosis and surveillance, integrated and multi-pronged control strategies should now pave the way for elimination of parasitic diseases in P.R. China. Experiences and lessons learned can stimulate control and elimination efforts of parasitic diseases in other parts of the world. PMID:23036110

Wasted Food: U.S. Consumers' Reported Awareness, Attitudes, and Behaviors.

PubMed

Neff, Roni A; Spiker, Marie L; Truant, Patricia L

2015-01-01

The U.S. wastes 31 to 40% of its post-harvest food supply, with a substantial portion of this waste occurring at the consumer level. Globally, interventions to address wasted food have proliferated, but efforts are in their infancy in the U.S. To inform these efforts and provide baseline data to track change, we performed a survey of U.S. consumer awareness, attitudes and behaviors related to wasted food. The survey was administered online to members of a nationally representative panel (N=1010), and post-survey weights were applied. The survey found widespread (self-reported) awareness of wasted food as an issue, efforts to reduce it, and knowledge about how to do so, plus moderately frequent performance of waste-reducing behaviors. Three-quarters of respondents said they discard less food than the average American. The leading motivations for waste reduction were saving money and setting an example for children, with environmental concerns ranked last. The most common reasons given for discarding food were concern about foodborne illness and a desire to eat only the freshest food. In some cases there were modest differences based on age, parental status, and income, but no differences were found by race, education, rural/urban residence or other demographic factors. Respondents recommended ways retailers and restaurants could help reduce waste. This is the first nationally representative consumer survey focused on wasted food in the U.S. It provides insight into U.S. consumers' perceptions related to wasted food, and comparisons to existing literature. The findings suggest approaches including recognizing that many consumers perceive themselves as being already-knowledgeable and engaged, framing messages to focus on budgets, and modifying existing messages about food freshness and aesthetics. This research also suggests opportunities to shift retail and restaurant practice, and identifies critical research gaps.

Wasted Food: U.S. Consumers' Reported Awareness, Attitudes, and Behaviors

PubMed Central

2015-01-01

The U.S. wastes 31 to 40% of its post-harvest food supply, with a substantial portion of this waste occurring at the consumer level. Globally, interventions to address wasted food have proliferated, but efforts are in their infancy in the U.S. To inform these efforts and provide baseline data to track change, we performed a survey of U.S. consumer awareness, attitudes and behaviors related to wasted food. The survey was administered online to members of a nationally representative panel (N=1010), and post-survey weights were applied. The survey found widespread (self-reported) awareness of wasted food as an issue, efforts to reduce it, and knowledge about how to do so, plus moderately frequent performance of waste-reducing behaviors. Three-quarters of respondents said they discard less food than the average American. The leading motivations for waste reduction were saving money and setting an example for children, with environmental concerns ranked last. The most common reasons given for discarding food were concern about foodborne illness and a desire to eat only the freshest food. In some cases there were modest differences based on age, parental status, and income, but no differences were found by race, education, rural/urban residence or other demographic factors. Respondents recommended ways retailers and restaurants could help reduce waste. This is the first nationally representative consumer survey focused on wasted food in the U.S. It provides insight into U.S. consumers’ perceptions related to wasted food, and comparisons to existing literature. The findings suggest approaches including recognizing that many consumers perceive themselves as being already-knowledgeable and engaged, framing messages to focus on budgets, and modifying existing messages about food freshness and aesthetics. This research also suggests opportunities to shift retail and restaurant practice, and identifies critical research gaps. PMID:26062025

Models and theories of prescribing decisions: A review and suggested a new model.

PubMed

Murshid, Mohsen Ali; Mohaidin, Zurina

2017-01-01

To date, research on the prescribing decisions of physician lacks sound theoretical foundations. In fact, drug prescribing by doctors is a complex phenomenon influenced by various factors. Most of the existing studies in the area of drug prescription explain the process of decision-making by physicians via the exploratory approach rather than theoretical. Therefore, this review is an attempt to suggest a value conceptual model that explains the theoretical linkages existing between marketing efforts, patient and pharmacist and physician decision to prescribe the drugs. The paper follows an inclusive review approach and applies the previous theoretical models of prescribing behaviour to identify the relational factors. More specifically, the report identifies and uses several valuable perspectives such as the 'persuasion theory - elaboration likelihood model', the stimuli-response marketing model', the 'agency theory', the theory of planned behaviour,' and 'social power theory,' in developing an innovative conceptual paradigm. Based on the combination of existing methods and previous models, this paper suggests a new conceptual model of the physician decision-making process. This unique model has the potential for use in further research.

Remotely Piloted Life-Saving Effort vehicles and emergency management: An analysis on revolutionizing humanitarian assistance in Pakistan.

PubMed

Nadeem, Ali Bin; Chandna, Ysa

The majority of the Pakistani public has known little of the unmanned aerial vehicles, also known for their onomatopoeically inspired name "drones," except the fact that it regularly rains Hellfire missiles in Pakistan, claiming the lives of many innocent Pakistanis settled in the western provinces. In actuality, in addition to their destructive capacities, these remotely piloted vehicles have been used since the turn of the century in a variety of live-saving and risk-reducing roles. This research article primarily addresses the third stage of Emergency management-response, with Pakistan being the primary region of research. This research article will first begin by diagnosing and accurately delineating the types of humanitarian crisis that grip Pakistan, devastating its land, exhausting its limited resources in its weak, and now almost archaic, disaster response strategy that results in the prolongation of its citizens' plight. Subsequently, this article will describe the history of the usage of unmanned vehicles, its multi-functional capacities, and its relevance in aiding humanitarian response efforts in disaster-stricken areas. Finally, this article will propose the introduction of Remotely Piloted Life-Saving Effort (RELIEF) vehicles in performing analysis and surveillance roles in Pakistan's disaster-prone and disaster-struck areas and its capacity to dramatically improve and expedite the existing relief supply delivery systems in place.

The Contribution for Improving GNSS Data and Derived Products for Solid Earth Sciences Promoted by EPOS-IP

NASA Astrophysics Data System (ADS)

Fernandes, R. M. S.; Bos, M. S.; Bruyninx, C.; Crocker, P.; Dousa, J.; Walpersdorf, A.; Socquet, A.; Avallone, A.; Ganas, A.; Ionescu, C.; Kenyeres, A.; Ofeigsson, B.; Ozener, H.; Vergnolle, M.; Lidberg, M.; Liwosz, T.; Soehne, W.; Bezdeka, P.; Cardoso, R.; Cotte, N.; Couto, R.; D'Agostino, N.; Deprez, A.; Fabian, A.; Gonçalves, H.; Féres, L.; Legrand, J.; Menut, J. L.; Nastase, E.; Ngo, K. M.; Sigurðarson, F.; Vaclavovic, P.

2017-12-01

The GNSS working group part of the EPOS-IP (European Plate Observing System - Implementation Phase) project oversees the implementation of services focused on GNSS data and derived products for the use of the geo-sciences community. The objective is to serve essentially the Solid Earth community, but other scientific and technical communities will also be able the benefit of the efforts being carried out to access the data (and derived products) of the European Geodetic Infrastructures. The geodetic component of EPOS is dealing essentially with implementing an e-infrastructure to store and disseminate continuous GNSS data (and derived solutions) from existing Research Infrastructures and new dedicated services. Present efforts are on developing an integrated software package, called GLASS, that will permit to disseminate quality controlled data (using special tools) in a seamless way from dozens of Geodetic Research Infrastructures in Europe. Conceptually, GLASS can be used in a single Research Infrastructure or in hundreds cooperative ones. We present and discuss the status of the implementation of these services, including also the generation of products - time-series, velocity fields and strain rate fields. In concrete, we will present the results of the current validation phase of these services and we will discuss in detail the technical and cooperative efforts being implemented. EPOS-IP is a project funded by the ESFRI European Union.

Critical soft landing technology issues for future US space missions

NASA Technical Reports Server (NTRS)

Macha, J. M.; Johnson, D. W.; Mcbride, D. D.

1992-01-01

A programmatic need for research and development to support parachute-based landing systems has not existed since the end of the Apollo missions in the mid-1970s. Now, a number of planned space programs require advanced landing capabilities for which the experience and technology base does not currently exist. New requirements for landing on land with controllable, gliding decelerators and for more effective impact attenuation devices justify a renewal of the landing technology development effort that existed during the Mercury, Gemini, and Apollo programs. A study was performed to evaluate the current and projected national capability in landing systems and to identify critical deficiencies in the technology base required to support the Assured Crew Return Vehicle and the Two-Way Manned Transportation System. A technology development program covering eight landing system performance issues is recommended.

Ras Dimer Formation as a New Signaling Mechanism and Potential Cancer Therapeutic Target

PubMed Central

Chen, Mo; Peters, Alec; Huang, Tao; Nan, Xiaolin

2016-01-01

The K-, N-, and HRas small GTPases are key regulators of cell physiology and are frequently mutated in human cancers. Despite intensive research, previous efforts to target hyperactive Ras based on known mechanisms of Ras signaling have been met with little success. Several studies have provided compelling evidence for the existence and biological relevance of Ras dimers, establishing a new mechanism for regulating Ras activity in cells additionally to GTP-loading and membrane localization. Existing data also start to reveal how Ras proteins dimerize on the membrane. We propose a dimer model to describe Ras-mediated effector activation, which contrasts existing models of Ras signaling as a monomer or as a 5-8 membered multimer. We also discuss potential implications of this model in both basic and translational Ras biology. PMID:26423697

Restoration ecology and invasive riparian plants: An introduction to the special section on Tamarix spp. in western North America

USGS Publications Warehouse

Shafroth, Patrick B.; Briggs, Mark K.

2008-01-01

River systems around the world are subject to various perturbations, including the colonization and spread of non-native species in riparian zones. Riparian resource managers are commonly engaged in efforts to control problematic non-native species and restore native habitats. In western North America, small Eurasian trees or shrubs in the genus Tamarixoccupy hundreds of thousands of hectares of riparian lands, and are the targets of substantial and costly control efforts and associated restoration activities. Still, significant information gaps exist regarding approaches used in control and restoration efforts and their effects on riparian ecosystems. In this special section of papers, eight articles address various aspects of control and restoration associated with Tamarix spp. These include articles focused on planning restoration and revegetation; a synthetic analysis of past restoration efforts; and several specific research endeavors examining plant responses, water use, and various wildlife responses (including birds, butterflies, and lizards). These articles represent important additions to the Tamarix spp. literature and contain many lessons and insights that should be transferable to other analogous situations in river systems globally.

Defining Attributes and Metrics of Effective Research Mentoring Relationships.

PubMed

Pfund, Christine; Byars-Winston, Angela; Branchaw, Janet; Hurtado, Sylvia; Eagan, Kevin

2016-09-01

Despite evidence of mentoring's importance in training researchers, studies to date have not yet determined which mentoring relationships have the most impact and what specific factors in those mentoring relationships contribute to key outcomes, such as the commitment to and persistence in research career paths for emerging researchers from diverse populations. Efforts to broaden participation and persistence in biomedical research careers require an understanding of why and how mentoring relationships work and their impact, not only to research training but also to promoting career advancement. This paper proposes core attributes of effective mentoring relationships, as supported by the literature and suggested by theoretical models of academic persistence. In addition, both existing and developing metrics for measuring the effectiveness of these attributes within mentoring relationships across diverse groups are presented, as well as preliminary data on these metrics from the authors' work.

Advancing Methods for U.S. Transgender Health Research

PubMed Central

Reisner, Sari L.; Deutsch, Madeline B.; Bhasin, Shalender; Bockting, Walter; Brown, George R.; Feldman, Jamie; Garofalo, Rob; Kreukels, Baudewijntje; Radix, Asa; Safer, Joshua D.; Tangpricha, Vin; T’Sjoen, Guy; Goodman, Michael

2016-01-01

Purpose of Review To describe methodological challenges, gaps, and opportunities in U.S. transgender health research. Recent Findings Lack of large prospective observational studies and intervention trials, limited data on risks and benefits of gender affirmation (e.g., hormones and surgical interventions), and inconsistent use of definitions across studies hinder evidence-based care for transgender people. Systematic high-quality observational and intervention-testing studies may be carried out using several approaches, including general population-based, health systems-based, clinic-based, venue-based, and hybrid designs. Each of these approaches has its strength and limitations; however, harmonization of research efforts is needed. Ongoing development of evidence-based clinical recommendations will benefit from a series of observational and intervention studies aimed at identification, recruitment, and follow-up of transgender people of different ages, from different racial, ethnic, and socioeconomic backgrounds and with diverse gender identities. Summary Transgender health research faces challenges that include standardization of lexicon, agreed-upon population definitions, study design, sampling, measurement, outcome ascertainment, and sample size. Application of existing and new methods is needed to fill existing gaps, increase the scientific rigor and reach of transgender health research, and inform evidence-based prevention and care for this underserved population. PMID:26845331

Development of a Research Participants’ Perception Survey to Improve Clinical Research

PubMed Central

Yessis, Jennifer L.; Kost, Rhonda G.; Lee, Laura M.; Coller, Barry S.; Henderson, David K.

2012-01-01

Abstract Introduction: Clinical research participants’ perceptions regarding their experiences during research protocols provide outcome‐based insights into the effectiveness of efforts to protect rights and safety, and opportunities to enhance participants’ clinical research experiences. Use of validated surveys measuring patient‐centered outcomes is standard in hospitals, yet no instruments exist to assess outcomes of clinical research processes. Methods: We derived survey questions from data obtained from focus groups comprised of research participants and professionals. We assessed the survey for face/content validity, and privacy/confidentiality protections and fielded it to research participants at 15 centers. We conducted analyses of response rates, sample characteristics, and psychometrics, including survey and item completion and analysis, internal consistency, item internal consistency, criterion‐related validity, and item usefulness. Responses were tested for fit into existing patient‐centered dimensions of care and new clinical research dimensions using Cronbach's alpha coefficient. Results: Surveys were mailed to 18,890 individuals; 4,961 were returned (29%). Survey completion was 89% overall; completion rates exceeded 90% for 88 of 93 evaluable items. Questions fit into three dimensions of patient‐centered care and two novel clinical research dimensions (Cronbach's alpha for dimensions: 0.69–0.85). Conclusions: The validated survey offers a new method for assessing and improving outcomes of clinical research processes. Clin Trans Sci 2012; Volume 5: 452–460 PMID:23253666

Driving CZTS to the SQ Limit: Solving the Open Circuit Voltage Problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haight, Richard A.; McCandless, Brian E.; Kummel, Andrew C.

2016-12-15

A key objective of this 3 year research effort was to reduce the open circuit voltage (Voc) deficit, defined as the difference between the absorber band gap and the measured Voc to below 475mV from values at the beginning of this work of 630-730mV. To achieve this reduction, along with the attendant goals of higher Voc and efficiency, detailed studies into the fundamental understanding of existing limitations were undertaken.

Electronic Waste: DOD Is Recovering Materials, but Several Factors May Hinder Near-Term Expansion of These Efforts

DTIC Science & Technology

2016-06-01

electronics with lithium ion batteries . In summary, these studies had the following results: • Recovery of tantalum from DOD’s electronic waste may be...expensive chemicals are required. • Recovery of cobalt from lithium ion batteries is possible, because recycling capability exists domestically and...quality. Additional research on the availability of lithium - ion batteries and the cost of recycling them would be necessary before recovery of this

Quasi-experimental study designs series-paper 13: realizing the full potential of quasi-experiments for health research.

PubMed

Rockers, Peter C; Tugwell, Peter; Røttingen, John-Arne; Bärnighausen, Till

2017-09-01

Although the number of quasi-experiments conducted by health researchers has increased in recent years, there clearly remains unrealized potential for using these methods for causal evaluation of health policies and programs globally. This article proposes five prescriptions for capturing the full value of quasi-experiments for health research. First, new funding opportunities targeting proposals that use quasi-experimental methods should be made available to a broad pool of health researchers. Second, administrative data from health programs, often amenable to quasi-experimental analysis, should be made more accessible to researchers. Third, training in quasi-experimental methods should be integrated into existing health science graduate programs to increase global capacity to use these methods. Fourth, clear guidelines for primary research and synthesis of evidence from quasi-experiments should be developed. Fifth, strategic investments should be made to continue to develop new innovations in quasi-experimental methodologies. Tremendous opportunities exist to expand the use of quasi-experimental methods to increase our understanding of which health programs and policies work and which do not. Health researchers should continue to expand their commitment to rigorous causal evaluation with quasi-experimental methods, and international institutions should increase their support for these efforts. Copyright © 2017 Elsevier Inc. All rights reserved.

Neural Networks for Computer Vision: A Framework for Specifications of a General Purpose Vision System

NASA Astrophysics Data System (ADS)

Skrzypek, Josef; Mesrobian, Edmond; Gungner, David J.

1989-03-01

The development of autonomous land vehicles (ALV) capable of operating in an unconstrained environment has proven to be a formidable research effort. The unpredictability of events in such an environment calls for the design of a robust perceptual system, an impossible task requiring the programming of a system bases on the expectation of future, unconstrained events. Hence, the need for a "general purpose" machine vision system that is capable of perceiving and understanding images in an unconstrained environment in real-time. The research undertaken at the UCLA Machine Perception Laboratory addresses this need by focusing on two specific issues: 1) the long term goals for machine vision research as a joint effort between the neurosciences and computer science; and 2) a framework for evaluating progress in machine vision. In the past, vision research has been carried out independently within different fields including neurosciences, psychology, computer science, and electrical engineering. Our interdisciplinary approach to vision research is based on the rigorous combination of computational neuroscience, as derived from neurophysiology and neuropsychology, with computer science and electrical engineering. The primary motivation behind our approach is that the human visual system is the only existing example of a "general purpose" vision system and using a neurally based computing substrate, it can complete all necessary visual tasks in real-time.

JSC Advanced Curation: Research and Development for Current Collections and Future Sample Return Mission Demands

NASA Technical Reports Server (NTRS)

Fries, M. D.; Allen, C. C.; Calaway, M. J.; Evans, C. A.; Stansbery, E. K.

2015-01-01

Curation of NASA's astromaterials sample collections is a demanding and evolving activity that supports valuable science from NASA missions for generations, long after the samples are returned to Earth. For example, NASA continues to loan hundreds of Apollo program samples to investigators every year and those samples are often analyzed using instruments that did not exist at the time of the Apollo missions themselves. The samples are curated in a manner that minimizes overall contamination, enabling clean, new high-sensitivity measurements and new science results over 40 years after their return to Earth. As our exploration of the Solar System progresses, upcoming and future NASA sample return missions will return new samples with stringent contamination control, sample environmental control, and Planetary Protection requirements. Therefore, an essential element of a healthy astromaterials curation program is a research and development (R&D) effort that characterizes and employs new technologies to maintain current collections and enable new missions - an Advanced Curation effort. JSC's Astromaterials Acquisition & Curation Office is continually performing Advanced Curation research, identifying and defining knowledge gaps about research, development, and validation/verification topics that are critical to support current and future NASA astromaterials sample collections. The following are highlighted knowledge gaps and research opportunities.

Framework for Human-Automation Collaboration: Conclusions from Four Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oxstrand, Johanna; Le Blanc, Katya L.; O'Hara, John

The Human Automation Collaboration (HAC) research project is investigating how advanced technologies that are planned for Advanced Small Modular Reactors (AdvSMR) will affect the performance and the reliability of the plant from a human factors and human performance perspective. The HAC research effort investigates the consequences of allocating functions between the operators and automated systems. More specifically, the research team is addressing how to best design the collaboration between the operators and the automated systems in a manner that has the greatest positive impact on overall plant performance and reliability. Oxstrand et al. (2013 - March) describes the efforts conductedmore » by the researchers to identify the research needs for HAC. The research team reviewed the literature on HAC, developed a model of HAC, and identified gaps in the existing knowledge of human-automation collaboration. As described in Oxstrand et al. (2013 – June), the team then prioritized the research topics identified based on the specific needs in the context of AdvSMR. The prioritization was based on two sources of input: 1) The preliminary functions and tasks, and 2) The model of HAC. As a result, three analytical studies were planned and conduced; 1) Models of Teamwork, 2) Standardized HAC Performance Measurement Battery, and 3) Initiators and Triggering Conditions for Adaptive Automation. Additionally, one field study was also conducted at Idaho Falls Power.« less

Another link to improving the working environment in acute care hospitals: registered nurses' spirit at work.

PubMed

Urban, Ann-Marie; Wagner, Joan I

2013-12-01

Hospitals are situated within historical and socio-political contexts; these influence the provision of patient care and the work of registered nurses (RNs). Since the early 1990s, restructuring and the increasing pressure to save money and improve efficiency have plagued acute care hospitals. These changes have affected both the work environment and the work of nurses. After recognizing this impact, healthcare leaders have dedicated many efforts to improving the work environment in hospitals. Admirable in their intent, these initiatives have made little change for RNs and their work environment, and thus, an opportunity exists for other efforts. Research indicates that spirit at work (SAW) not only improves the work environment but also strengthens the nurse's power to improve patient outcomes and contribute to a high-quality workplace. In this paper, we present findings from our research that suggest SAW be considered an important component in improving the work environment in acute care hospitals.

Delivering vaccines to the people who need them most.

PubMed

Barocchi, Michèle Anne; Rappuoli, Rino

2015-06-19

Thanks to the Global Alliance for Vaccines and Immunization (GAVI), the Vaccine Fund and the Bill & Melinda Gates Foundation, the global health community has made enormous progress in providing already existing vaccines to developing countries. However, there still exists a gap to develop vaccines for which there is no market in the Western world, owing to low economic incentives for the private sector to justify the investments necessary for vaccine development. In many cases, industry has the technologies, but lacks the impetus to direct resources to develop these vaccine products. The present emergency with the Ebola vaccine provides us an excellent example where a vaccine was feasible several years ago, but the global health community waited for a humanitarian disaster to direct efforts and resources to develop this vaccine. In the beginning of 2015, the first large-scale trials of two experimental vaccines against Ebola virus disease have begun in West Africa. During the past few years, several institutions have dedicated efforts to the development of vaccines against diseases present only in low-income countries. These include the International Vaccine Institute, the Novartis Vaccines Institute for Global Health, the Hilleman Institute, the Sabin Vaccine Institute and the Infectious Disease Research Institute. Nevertheless, solving this problem requires a more significant global effort than that currently invested. These efforts include a clear policy, global coordination of funds dedicated to the development of neglected disease and an agreement on regulatory strategies and incentives for the private sector. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Ecological assessment of sagebrush grasslands in eastern Wyoming

Treesearch

Amy C. Ganguli; Jonathan B. Haufler; Carolyn A. Mehl; Scott D. Yeats

2011-01-01

An understanding of existing ecosystem conditions is necessary for planning efforts that include formulation of landscape conservation goals and implementation strategies. In support of a landscape planning effort for a 946,000-ac mixed-ownership area in eastern Wyoming, we used remote sensing and field sampling to assess existing ecosystem conditions of terrestrial...

Institute for Advanced Materials at University of Louisville

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunkara, Mahendra; Sumaneskara, Gamini; Starr, Thomas L

2009-10-29

In this project, a university-wide, academic center has been established entitled Institute for Advanced Materials and Renewable Energy. In this institute, a comprehensive materials characterization facility has been established by co-locating several existing characterization equipment and acquiring several state of the art instrumentation such as field emission transmission electron microscope, scanning electron microscope, high resolution X-ray diffractometer, Particle Size Distribution/Zeta Potential measurement system, and Ultra-microtome for TEM specimen. In addition, a renewable energy conversion and storage research facility was also established by acquiring instrumentation such as UV-Vis absorption spectroscopy, Atomic Layer Deposition reactor, Solar light simulator, oxygen-free glove box, potentiostat/galvanostatsmore » and other miscellaneous items. The institute is staffed with three full-time staff members (one senior research technologist, a senior PhD level research scientist and a junior research scientist) to enable proper use of the techniques. About thirty faculty, fifty graduate students and several researchers access the facilities on a routine basis. Several industry R&D organizations (SudChemie, Optical Dynamics and Hexion) utilize the facility. The established Institute for Advanced Materials at UofL has three main objectives: (a) enable a focused research effort leading to the rapid discovery of new materials and processes for advancing alternate energy conversion and storage technologies; (b) enable offering of several laboratory courses on advanced materials science and engineering; and (c) develop university-industry partnerships based on the advanced materials research. The Institute's efforts were guided by an advisory board comprising eminent researchers from outside KY. Initial research efforts were focused on the discovery of new materials and processes for solar cells and Li ion battery electrodes. Initial sets of results helped PIs to secure a successful EPSCoR cluster implementation grant by teaming with additional researchers from UK. In addition to research efforts, the project enabled several other outcomes: (a) helped recruit a junior faculty member (Dr. Moises Carreon) and establish a lab focused on meso-porous materials toward separation and catalysis; (b) enabled offering of three new, graduate level courses (Materials characterization using spectroscopy and microscopy; Electron and x-ray diffraction; and renewable energy systems); and (c) mentoring of a junior faculty members (Dr. Gerold Willing).« less

Long-Term Network Experiments and Interdisciplinary Campaigns Conducted by the USDA-Agricultural Research Service

NASA Astrophysics Data System (ADS)

Goodrich, D. C.; Kustas, W. P.; Cosh, M. H.; Moran, S. M.; Marks, D. G.; Jackson, T. J.; Bosch, D. D.; Rango, A.; Seyfried, M. S.; Scott, R. L.; Prueger, J. H.; Starks, P. J.; Walbridge, M. R.

2014-12-01

The USDA-Agricultural Research Service has led, or been integrally involved in, a myriad of interdisciplinary field campaigns in a wide range of locations both nationally and internationally. Many of the shorter campaigns were anchored over the existing national network of ARS Experimental Watersheds and Rangelands. These long-term outdoor laboratories provided a critical knowledge base for designing the campaigns as well as historical data, hydrologic and meteorological infrastructure coupled with shop, laboratory, and visiting scientist facilities. This strong outdoor laboratory base enabled cost-efficient campaigns informed by historical context, local knowledge, and detailed existing watershed characterization. These long-term experimental facilities have also enabled much longer term lower intensity experiments, observing and building an understanding of both seasonal and inter-annual biosphere-hydrosphere-atmosphere interactions across a wide range of conditions. A sampling of these experiments include MONSOON'90, SGP97, SGP99, Washita'92, Washita'94, SMEX02-05 and JORNEX series of experiments, SALSA, CLASIC and longer-term efforts over the ARS Little Washita, Walnut Gulch, Little River, Reynolds Creek, and OPE3 Experimental Watersheds. This presentation will review some of the highlights and key findings of these campaigns and long-term efforts including the inclusion of many of the experimental watersheds and ranges in the Long-Term Agro-ecosystems Research (LTAR) network. The LTAR network also contains several locations that are also part of other observational networks including the CZO, LTER, and NEON networks. Lessons learned will also be provided for scientists initiating their participation in large-scale, multi-site interdisciplinary science.

Commitment to a purpose in life: An antidote to the suffering by individuals with social anxiety disorder

PubMed Central

Kashdan, Todd B.; McKnight, Patrick E.

2014-01-01

Recent acceptance and mindfulness based cognitive-behavioral interventions explicitly target the clarification and commitment to a purpose in life. Yet, scant empirical evidence exists on the value of purpose as a mechanism relevant to psychopathology or well-being. The present research explored daily (within-person) fluctuations in purposeful pursuits and well-being in adults with and without the generalized subtype of Social Anxiety Disorder (SAD); a community sample of 84 (41 with generalized SAD). After completing an idiographic measure of purpose in life, participants monitored their effort and progress toward this purpose along with their well-being each day. . Across two weeks of daily reports, we found that healthy controls reported increased self-esteem, meaning in life, positive emotions, and decreased negative emotions. People with SAD experienced substantial boosts in well-being indicators on days characterized by significant effort or progress toward their life purpose. We found no evidence for the reverse direction (with well-being boosting the amount of effort or progress that people with SAD devote to their purpose) and effects could not be attributed to comorbid mood or anxiety disorders. Results provide evidence for how commitment to a purpose in life enriches the daily existence of people with SAD. The current study supports principles that underlie what many clinicians are already doing with clients for SAD. PMID:23795592

Research support for effective state and community tobacco control programme response to electronic nicotine delivery systems.

PubMed

Schmitt, Carol L; Lee, Youn Ok; Curry, Laurel E; Farrelly, Matthew C; Rogers, Todd

2014-07-01

To identify unmet research needs of state and community tobacco control practitioners pertaining to electronic nicotine delivery systems (ENDS or e-cigarettes) that would inform policy and practice efforts at the state and community levels, and to describe ENDS-related research and dissemination activities of the National Cancer Institute-funded State and Community Tobacco Control Research Initiative. To determine specific research gaps relevant to state and community tobacco control practice, we analysed survey data collected from tobacco control programmes (TCPs) in all 50 U.S. states and the District of Columbia (N=51). Survey items covered a range of ENDS issues: direct harm to users, harm of secondhand vapour, cessation, flavours, constituents and youth access. There is no ENDS topic on which a majority of state TCP managers feel very informed. They feel least informed about harms of secondhand vapour while also reporting that this information is among the most important for their programme. A majority (N=31) of respondents indicated needs for research on the implications of ENDS products for existing policies. TCP managers report that ENDS research is highly important for practice and need research-based information to inform decision making around the inclusion of ENDS in existing tobacco control policies. For optimal relevance to state and community TCPs, research on ENDS should prioritise study of the health effects of ENDS use and secondhand exposure to ENDS vapour in the context of existing tobacco control policies. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Redesigning the DOE Data Explorer to embed dataset relationships at the point of search and to reflect landing page organization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Studwell, Sara; Robinson, Carly; Elliott, Jannean

Scientific research is producing ever-increasing amounts of data. Organizing and reflecting relationships across data collections, datasets, publications, and other research objects are essential functionalities of the modern science environment, yet challenging to implement. Landing pages are often used for providing ‘big picture’ contextual frameworks for datasets and data collections, and many large-volume data holders are utilizing them in thoughtful, creative ways. The benefits of their organizational efforts, however, are not realized unless the user eventually sees the landing page at the end point of their search. What if that organization and ‘big picture’ context could benefit the user at themore » beginning of the search? That is a challenging approach, but The Department of Energy’s (DOE) Office of Scientific and Technical Information (OSTI) is redesigning the database functionality of the DOE Data Explorer (DDE) with that goal in mind. Phase I is focused on redesigning the DDE database to leverage relationships between two existing distinct populations in DDE, data Projects and individual Datasets, and then adding a third intermediate population, data Collections. Mapped, structured linkages, designed to show user relationships, will allow users to make informed search choices. These linkages will be sustainable and scalable, created automatically with the use of new metadata fields and existing authorities. Phase II will study selected DOE Data ID Service clients, analyzing how their landing pages are organized, and how that organization might be used to improve DDE search capabilities. At the heart of both phases is the realization that adding more metadata information for cross-referencing may require additional effort for data scientists. Finally, OSTI’s approach seeks to leverage existing metadata and landing page intelligence without imposing an additional burden on the data creators.« less

Our living resources: A report to the nation on the distribution, abundance, and health of U.S. plants, animals, and ecosystems

USGS Publications Warehouse

LaRoe, Edward T.; Farris, Gaye S.; Puckett, Catherine E.; Doran, Peter D.; Mac, Michael J.

1995-01-01

This report on the distribution, abundance, and health of our nation's biological resources is the first product of the National Biological Service’s Status and Trends Program. This information has many potential uses: it can document successful management efforts so resource managers will know what has worked well; it can identify problems so managers can take early action to restore the resource in the most cost-efficient manner; and it can be used to highlight areas where additional research is needed, such as to determine why certain ecological changes are occurring. This report will also be useful to teachers, students, journalists, and citizens in general who are interested in national resource issues.Another purpose of this report is to help identify gaps in existing resource inventory and monitoring programs. It contains information collected by a variety of existing research and monitoring efforts by scientists in the National Biological Service, other federal and state agencies, academia, and the private sector. The programs that produced the information in this document were not developed in a coordinated fashion to produce an integrated, comprehensive picture of the status and trends of our nation’s resources; rather, each was developed for its own particular purpose, usually to help manage a specific resource. Thus, even though articles vary greatly in scope, design, and purpose, this report has identified and attempted to combine many of the existing information sources into a broad picture of the condition of our resources. In the future, these sources will be complemented by additional information from other sources - such as state agencies and other inventory and monitoring studies - to fill in the gaps of knowledge and to provide a more complete understanding of the status of our living resources.

Redesigning the DOE Data Explorer to embed dataset relationships at the point of search and to reflect landing page organization

DOE PAGES

Studwell, Sara; Robinson, Carly; Elliott, Jannean

2017-04-04

Scientific research is producing ever-increasing amounts of data. Organizing and reflecting relationships across data collections, datasets, publications, and other research objects are essential functionalities of the modern science environment, yet challenging to implement. Landing pages are often used for providing ‘big picture’ contextual frameworks for datasets and data collections, and many large-volume data holders are utilizing them in thoughtful, creative ways. The benefits of their organizational efforts, however, are not realized unless the user eventually sees the landing page at the end point of their search. What if that organization and ‘big picture’ context could benefit the user at themore » beginning of the search? That is a challenging approach, but The Department of Energy’s (DOE) Office of Scientific and Technical Information (OSTI) is redesigning the database functionality of the DOE Data Explorer (DDE) with that goal in mind. Phase I is focused on redesigning the DDE database to leverage relationships between two existing distinct populations in DDE, data Projects and individual Datasets, and then adding a third intermediate population, data Collections. Mapped, structured linkages, designed to show user relationships, will allow users to make informed search choices. These linkages will be sustainable and scalable, created automatically with the use of new metadata fields and existing authorities. Phase II will study selected DOE Data ID Service clients, analyzing how their landing pages are organized, and how that organization might be used to improve DDE search capabilities. At the heart of both phases is the realization that adding more metadata information for cross-referencing may require additional effort for data scientists. Finally, OSTI’s approach seeks to leverage existing metadata and landing page intelligence without imposing an additional burden on the data creators.« less

Women, violence with intimates, and substance abuse: relevant theory, empirical findings, and recommendations for future research.

PubMed

Hien, D; Hien, N M

1998-08-01

Evidence from the disparate domains of anthropology, criminology, psychology, and sociology indicates that women are involved in many of the same acts of aggression and violence as men, and that substance use may play an important role in these acts. Yet little is known of the pathways between violence and drugs for women. The aims of this paper are threefold: 1) To review and integrate existing literature addressing female violence and substance abuse, presenting available epidemiology, theories, and research applicable to the study of this problem. 2) To examine the political and methodological obstacles to conducting systematic research on female aggressiveness. 3) To offer recommendations for future epidemiological, preventive, and therapeutic research efforts in this vital yet grossly understudied area.

The Abbreviation of Personality, or how to Measure 200 Personality Scales with 200 Items

PubMed Central

Yarkoni, Tal

2010-01-01

Personality researchers have recently advocated the use of very short personality inventories in order to minimize administration time. However, few such inventories are currently available. Here I introduce an automated method that can be used to abbreviate virtually any personality inventory with minimal effort. After validating the method against existing measures in Studies 1 and 2, a new 181-item inventory is generated in Study 3 that accurately recaptures scores on 8 different broadband inventories comprising 203 distinct scales. Collectively, the results validate a powerful new way to improve the efficiency of personality measurement in research settings. PMID:20419061

Suicide and Suicide Risk in Lesbian, Gay, Bisexual, and Transgender Populations: Review and Recommendations

PubMed Central

Haas, Ann P.; Eliason, Mickey; Mays, Vickie M.; Mathy, Robin M.; Cochran, Susan D.; D'Augelli, Anthony R.; Silverman, Morton M.; Fisher, Prudence W.; Hughes, Tonda; Rosario, Margaret; Russell, Stephen T.; Malley, Effie; Reed, Jerry; Litts, David A.; Haller, Ellen; Sell, Randall L.; Remafedi, Gary; Bradford, Judith; Beautrais, Annette L.; Brown, Gregory K.; Diamond, Gary M.; Friedman, Mark S.; Garofalo, Robert; Turner, Mason S.; Hollibaugh, Amber; Clayton, Paula J.

2011-01-01

Despite strong indications of elevated risk of suicidal behavior in lesbian, gay, bisexual, and transgender people, limited attention has been given to research, interventions or suicide prevention programs targeting these populations. This article is a culmination of a three-year effort by an expert panel to address the need for better understanding of suicidal behavior and suicide risk in sexual minority populations, and stimulate the development of needed prevention strategies, interventions and policy changes. This article summarizes existing research findings, and makes recommendations for addressing knowledge gaps and applying current knowledge to relevant areas of suicide prevention practice. PMID:21213174

Problem gambling in the workplace, characteristics of employees seeking help.

PubMed

Hawley, Carolyn E; Glenn, Margaret K; Diaz, Sebastian

2007-01-01

Few rigorous research studies exist to define the impact problem gambling may have on the workforce and the workplace. This study is an initial attempt to address this void by exploring the vocational patterns and demographics of callers with self report gambling problems to a state helpline. It utilizes Chi-squared Automatic Interaction (CHAID) Technique analysis to assess 1072 working age callers with gambling related problems. The goal of this exploratory investigation is to determine if the issue of problem gambling in the workplace warrants further research and, potentially, design of interventions. Discussion centers on the use of the information for development of employer based prevention and intervention efforts.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rebecca E. Smith

Internationally, the nuclear industry is represented by both commercial utilities and research institutions. Over the past two decades many of these entities have had to relocate inventories of spent nuclear fuel from underwater storage to dry storage. These efforts were primarily prompted by two factors: insufficient storage capacity (potentially precipitated by an open-ended nuclear fuel cycle) or deteriorating quality of existing underwater facilities. The intent of developing this bibliography is to assess what issues associated with fuel drying have been identified, to consider where concerns have been satisfactorily addressed, and to recommend where additional research would offer the most valuemore » to the commercial industry and the U. S. Department of Energy.« less

High-Fidelity Multi-Rotor Unmanned Aircraft System Simulation Development for Trajectory Prediction Under Off-Nominal Flight Dynamics

NASA Technical Reports Server (NTRS)

Foster, John V.; Hartman, David C.

2017-01-01

The NASA Unmanned Aircraft System (UAS) Traffic Management (UTM) project is conducting research to enable civilian low-altitude airspace and UAS operations. A goal of this project is to develop probabilistic methods to quantify risk during failures and off nominal flight conditions. An important part of this effort is the reliable prediction of feasible trajectories during off-nominal events such as control failure, atmospheric upsets, or navigation anomalies that can cause large deviations from the intended flight path or extreme vehicle upsets beyond the normal flight envelope. Few examples of high-fidelity modeling and prediction of off-nominal behavior for small UAS (sUAS) vehicles exist, and modeling requirements for accurately predicting flight dynamics for out-of-envelope or failure conditions are essentially undefined. In addition, the broad range of sUAS aircraft configurations already being fielded presents a significant modeling challenge, as these vehicles are often very different from one another and are likely to possess dramatically different flight dynamics and resultant trajectories and may require different modeling approaches to capture off-nominal behavior. NASA has undertaken an extensive research effort to define sUAS flight dynamics modeling requirements and develop preliminary high fidelity six degree-of-freedom (6-DOF) simulations capable of more closely predicting off-nominal flight dynamics and trajectories. This research has included a literature review of existing sUAS modeling and simulation work as well as development of experimental testing methods to measure and model key components of propulsion, airframe and control characteristics. The ultimate objective of these efforts is to develop tools to support UTM risk analyses and for the real-time prediction of off-nominal trajectories for use in the UTM Risk Assessment Framework (URAF). This paper focuses on modeling and simulation efforts for a generic quad-rotor configuration typical of many commercial vehicles in use today. An overview of relevant off-nominal multi-rotor behaviors will be presented to define modeling goals and to identify the prediction capability lacking in simplified models of multi-rotor performance. A description of recent NASA wind tunnel testing of multi-rotor propulsion and airframe components will be presented illustrating important experimental and data acquisition methods, and a description of preliminary propulsion and airframe models will be presented. Lastly, examples of predicted off-nominal flight dynamics and trajectories from the simulation will be presented.

Identifying research priorities for health care priority setting: a collaborative effort between managers and researchers

PubMed Central

Smith, Neale; Mitton, Craig; Peacock, Stuart; Cornelissen, Evelyn; MacLeod, Stuart

2009-01-01

Background To date there has been relatively little published about how research priorities are set, and even less about methods by which decision-makers can be engaged in defining a relevant and appropriate research agenda. We report on a recent effort in British Columbia to have researchers and decision-makers jointly establish an agenda for future research into questions of resource allocation. Methods The researchers enlisted decision-maker partners from each of British Columbia's six health authorities. Three forums were held, at which researchers and decision-makers from various levels in the health authorities considered possible research areas related to three key focus areas: (1) generation and use of decision criteria and measurement of 'benefit' against such criteria; (2) identification of so-called 'disinvestment' opportunities; and (3) evaluation of the effectiveness of priority setting procedures. Detailed notes were taken from each forum and synthesized into a set of qualitative themes. Results Forum participants suggested that future research into healthcare priority setting would benefit from studies that were longitudinal, comparative, and/or interdisciplinary. As well, participants identified two broad theme areas in which specific research projects were deemed desirable. First, future research might usefully consider how formal priority setting and resource allocation projects are situated within a larger organizational and political context. Second, additional research efforts should be devoted to better understanding and improving the actual implementation of priority setting frameworks, particularly with respect to issues of change management and the resolution of impediments to action on recommendations for resource allocation. Conclusion We were able to validate the importance of initial areas posed to the group and observed emergence of additional concerns and directions of critical importance to these decision-makers at this time. It is likely that the results are broadly applicable to other healthcare contexts. The implementation of this research agenda in British Columbia will depend upon the ability of the researchers and decision-makers to develop particular projects that fit within the constraints of existing funding opportunities. The process of engagement itself had benefits in terms of connecting decision-makers with their peers and sparking increased interest in the use and refinement of priority setting frameworks. PMID:19754969

Research and Development at NASA

NASA Technical Reports Server (NTRS)

2004-01-01

The Vision for Space Exploration marks the next segment of NASA's continuing journey to find answers to compelling questions about the origins of the solar system, the existence of life beyond Earth, and the ability of humankind to live on other worlds. The success of the Vision relies upon the ongoing research and development activities conducted at each of NASA's 10 field centers. In an effort to promote synergy across NASA as it works to meet its long-term goals, the Agency restructured its Strategic Enterprises into four Mission Directorates that align with the Vision. Consisting of Exploration Systems, Space Operations, Science, and Aeronautics Research, these directorates provide NASA Headquarters and the field centers with a streamlined approach to continue exploration both in space and on Earth.

Summary: The natural history and immunobiology of Chlamydia trachomatis genital infection and implications for Chlamydia control.

PubMed

Gottlieb, Sami L; Martin, David H; Xu, Fujie; Byrne, Gerald I; Brunham, Robert C

2010-06-15

In 2008, the US Centers for Disease Control and Prevention held the Chlamydia Immunology and Control Expert Advisory Meeting to foster a dialogue among basic scientists, clinical researchers, and epidemiologists studying genital Chlamydia trachomatis infection. The objectives of the meeting were to determine key questions related to C. trachomatis natural history and immunobiology, with implications for control programs;to review existing data on these key questions; and to delineate research needs to address remaining gaps in knowledge. The 9 articles in this supplement to The Journal of Infectious Diseases describe salient findings presented at the 2008 meeting, and this commentary summarizes and synthesizes these articles and discusses implications for chlamydia control efforts and future research priorities.

Extraterrestrial Life

NASA Technical Reports Server (NTRS)

Klein, M. J.

1993-01-01

Extraterrestrial Intelligence is intelligent life that developed somewhere other than the earth. Such life has not yet been discovered. However, scientific research, including astronomy, biology, planetary science and studies of fossils here on earth have led many scientists to conclude that such life may exist on planets orbiting at least some of the hundreds of billions of stars in our Milky Way Galaxy. Today, some researchers are trying to find evidence for extraterrestrial intelligence. This effort is often called SETI, which stands for Search for Extraterrestrial Intelligence. SETI researchers decided that looking for evidence of their technology might be the best way to discover other intelligent life in the Galaxy. They decided to use large radio telescopes to search the sky over a wide range of radio frequencies...

Geographic overlaps between priority areas for forest carbon-storage efforts and those for delivering peacebuilding programs: implications for policy design

NASA Astrophysics Data System (ADS)

Castro-Nunez, Augusto; Mertz, Ole; Sosa, Chrystian C.

2017-05-01

Of the countries considering national-level policies for incentivizing reductions in forest-based greenhouse gas emissions (REDD+), some 25 are experiencing (or are emerging from) armed-conflicts. It has been hypothesized that the outcomes of the interactions between carbon-storage and peacebuilding efforts could result in either improved or worsened forest conservation and likewise increased or decreased conflict. Hence, for this study we explore potential interactions between forest carbon-storage and peacebuilding efforts, with Colombia as a case study. Spatial associations between biomass carbon and three conflict-related variables suggest that such interactions may exist. Nonetheless, while priority areas for carbon-focused conservation are presumably those at highest risks of deforestation, our research indicates that forests with lower risk of deforestation are typically those affected by armed-conflict. Our findings moreover highlight three possible roles played by Colombian forested municipalities in armed groups’ military strategies: venues for battle, hideouts, and sources of natural resources to finance war.

Biofuels: balancing risks and rewards.

PubMed

Thornley, Patricia; Gilbert, Paul

2013-02-06

This paper describes a framework that can be used to evaluate the environmental risks and benefits associated with biofuel production. It uses the example of biodiesel produced from Argentinean soy to show how such a framework can be used to conceptualize trade-offs between different environmental, social and economic impacts of biofuel production. Results showing the greenhouse-gas savings and overall life-cycle impact of different 'soy-biodiesel' production methods are presented. These impacts and the significance of uncertainty in overall assessments of key parameters, such as greenhouse-gas savings, are discussed. It is shown that, even where sufficient knowledge exists to be able to quantify these impacts, the sustainability of supply of a particular biofuel is inextricably linked to values and ethical judgements. However, tailoring certification efforts to the issues that are most likely to make a significant difference to the overall sustainability could improve the effectiveness of certification efforts. The potential for a framework to guide and focus certification efforts is discussed and future research and policy priorities suggested.

ALS Biomarkers for Therapy Development: State of the Field & Future Directions

PubMed Central

Benatar, Michael; Boylan, Kevin; Jeromin, Andreas; Rutkove, Seward B.; Berry, James; Atassi, Nazem; Bruijn, Lucie

2015-01-01

Biomarkers have become the focus of intense research in the field of amyotrophic lateral sclerosis (ALS), with the hope that they might aid therapy development efforts. Notwithstanding the discovery of many candidate biomarkers, none have yet emerged as validated tools for drug development. In this review we present a nuanced view of biomarkers based on the perspective of the FDA; highlight the distinction between discovery and validation; describe existing and emerging resources; review leading biological fluid-based, electrophysiological and neuroimaging candidates relevant to therapy development efforts; discuss lessons learned from biomarker initiatives in related neurodegenerative diseases; and outline specific steps that we, as a field, might take in order to hasten the development and validation of biomarkers that will prove useful in enhancing efforts to develop effective treatments for ALS patients. Most important among these perhaps is the proposal to establish a federated ALS Biomarker Consortium (ABC) in which all interested and willing stakeholders may participate with equal opportunity to contribute to the broader mission of biomarker development and validation. PMID:26574709

Building a sustainable complementary and alternative medicine research network in Europe.

PubMed

Reiter, Bettina; Baumhöfener, Franziska; Dlaboha, Meike; Odde Madsen, Jesper; Regenfelder, Stephanie; Weidenhammer, Wolfgang

2012-01-01

Since CAMbrella is a networking project funded by the European Commission explicitly to build and sustain a complementary and alternative medicine (CAM) research network in Europe, communication and dissemination play a large role and form a work package of their own. The present article gives an outline of the communication and dissemination work in the CAMbrella consortium. The intensive building of sound internal communication is an essential part in establishing a functioning structure for collaboration in a diverse group of 16 partner institutions from 12 countries, as exists in the CAMbrella project. The means and tools for dissemination of results to the scientific community and the European public at large, as well as to the European policy makers, are presented. The development of the corporate design and a dissemination strategy are described in detail. In addition, some basic information regarding previous CAM research efforts, which might be interesting for future consortium building in the field of CAM research, is given. Internal communication within a heterogeneous research group, the maintenance of a work-oriented style of communication and a consensus oriented effort in establishing dissemination tools and products will be essential for any future consortium in the CAM field. The outlook shows the necessity for active political encouragement of CAM research and the desideratum of a Pan-European institution analogous to the NIH (National Institutes of Health) in the USA.

FY08 Engineering Research and Technology Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minichino, C; McNichols, D

2009-02-24

This report summarizes the core research, development, and technology accomplishments in Lawrence Livermore National Laboratory's Engineering Directorate for FY2008. These efforts exemplify Engineering's more than 50-year history of developing and applying the technologies needed to support the Laboratory's national security missions. A partner in every major program and project at the Laboratory throughout its existence, Engineering has prepared for this role with a skilled workforce and technical resources developed through both internal and external venues. These accomplishments embody Engineering's mission: 'Enable program success today and ensure the Laboratory's vitality tomorrow.' Engineering's mission is carried out through basic research and technologymore » development. Research is the vehicle for creating competencies that are cutting-edge, or require discovery-class groundwork to be fully understood. Our technology efforts are discipline-oriented, preparing research breakthroughs for broader application to a variety of Laboratory needs. The term commonly used for technology-based projects is 'reduction to practice.' As we pursue this two-pronged approach, an enormous range of technological capabilities result. This report combines our work in research and technology into one volume, organized into thematic technical areas: Engineering Modeling and Simulation; Measurement Technologies; Micro/Nano-Devices and Structures; Engineering Systems for Knowledge and Inference; and Energy Manipulation. Our investments in these areas serve not only known programmatic requirements of today and tomorrow, but also anticipate the breakthrough engineering innovations that will be needed in the future.« less

Exobiological Exploration of Europa (E3) Europa Lander

NASA Technical Reports Server (NTRS)

Stillwagen, F. H.; Manvi, Ramachandra; Seywald, Hans; Park, Sang-Young; Kolacinski, Rick

2002-01-01

The search for life outside Earth's protected atmosphere is a compelling testament to the quest by mankind to determine if "we" are alone in the universe. The phenomenal success of the NASA Galileo spacecraft has indicated that the moons of Jupiter, and most notably Europa, may indeed contain subsurface liquid under an icy surface. This speculation of a salty liquid subsurface fuels expert opinions that biological products may exist. The Revolutionary Aerospace Systems Concepts (RASC) effort at Langley Research Center, initiated by NASA Headquarters, pushes NASA and the Aerospace/Science community to target advanced evolutionary technology usage to provide a Europa Lander concept targeted for completion within the next 50 years. The study effort indicates the use of certain advanced technologies to achieve a subsurface penetrator and liquid explorer in the approximately 2040 timeframe.

An alternative framework for responding to the amphibian crisis

USGS Publications Warehouse

Muths, Erin L.; Fisher, Robert N.

2017-01-01

Volumes of data illustrate the severity of the crisis affecting amphibians, where > 32% of amphibians worldwide are threatened with declining populations. Although there have been isolated victories, the current approach to the issue is unsuccessful. We suggest that a radically different approach, something akin to human emergency response management (i.e. the Incident Command System), is one alternative to addressing the inertia and lack of cohesion in responding to amphibian issues. We acknowledge existing efforts and the useful research that has been conducted, but we suggest that a change is warranted and that the identification of a new amphibian chytrid provides the impetus for such a change. Our goal is to recognize that without a centralized effort we (collectively) are likely to fail in responding to this challenge.

ISMIP6: Ice Sheet Model Intercomparison Project for CMIP6

NASA Technical Reports Server (NTRS)

Nowicki, S.

2015-01-01

ISMIP6 (Ice Sheet Model Intercomparison Project for CMIP6) targets the Cryosphere in a Changing Climate and the Future Sea Level Grand Challenges of the WCRP (World Climate Research Program). Primary goal is to provide future sea level contribution from the Greenland and Antarctic ice sheets, along with associated uncertainty. Secondary goal is to investigate feedback due to dynamic ice sheet models. Experiment design uses and augment the existing CMIP6 (Coupled Model Intercomparison Project Phase 6) DECK (Diagnosis, Evaluation, and Characterization of Klima) experiments. Additonal MIP (Model Intercomparison Project)- specific experiments will be designed for ISM (Ice Sheet Model). Effort builds on the Ice2sea, SeaRISE (Sea-level Response to Ice Sheet Evolution) and COMBINE (Comprehensive Modelling of the Earth System for Better Climate Prediction and Projection) efforts.

Youth tobacco prevention mass media campaigns: past, present, and future directions.

PubMed

Farrelly, M C; Niederdeppe, J; Yarsevich, J

2003-06-01

This paper focuses on countermarketing efforts aimed at curbing youth smoking. We review the literature on the effectiveness of tobacco countermarketing campaigns, characterise current state and national campaign approaches, present findings from qualitative approaches and laboratory experiments that explore a variety of messages (for example, health consequences, industry manipulation), and discuss newer, non-traditional approaches to countermarketing. In conclusion, we outline research needed to fill gaps in our existing knowledge and discuss future directions in tobacco countermarketing aimed at youth.

Air quality aerometric data for the city of Cleveland from 1967 to 1970 for sulphur dioxide, suspended particulates, and nitrogen dioxide

NASA Technical Reports Server (NTRS)

Neustadter, H. E.; King, R. B.; Fordyce, J. S.; Burr, J. C., Jr.

1972-01-01

The NASA Lewis Research Center is assisting the City of Cleveland, Ohio, in its effort to monitor its air pollution. This report describes the Cleveland program of the past 4 years and the supportive Lewis program currently being developed. The data accumulated by Cleveland over the past 4 years are presented together with some preliminary statistical analyses indicating in a semiquantitive manner the degree of air pollution existing within the boundaries of Cleveland.

Assessing Cybercrime Through the Eyes of the WOMBAT

NASA Astrophysics Data System (ADS)

Dacier, Marc; Leita, Corrado; Thonnard, Olivier; van Pham, Hau; Kirda, Engin

The WOMBAT project is a collaborative European funded research project that aims at providing new means to understand the existing and emerging threats that are targeting the Internet economy and the net citizens. The approach carried out by the partners include a data collection effort as well as some sophisticated analysis techniques. In this chapter, we present one of the threats-related data collection system in use by the project, as well as some of the early results obtained when digging into these data sets.

Developments and potential of radiation processing in the Philippines

NASA Astrophysics Data System (ADS)

Singson, C.; Carmona, C.

This paper describes the research and development activities in three areas of radiation processing, namely: food irradiation, medical product sterilization and wood plastic combination. Plans and efforts exerted to acquire a larger gamma source to augment our present 5,000 curie source are discussed. Cost estimates for a radiation facility is presented on the basis of the market potential of food irradiation and medical product sterilization. Existing local industries that can benefit from the adaptation of irradiation technology in their processing requirements is described.

Planning applications in image analysis

NASA Technical Reports Server (NTRS)

Boddy, Mark; White, Jim; Goldman, Robert; Short, Nick, Jr.

1994-01-01

We describe two interim results from an ongoing effort to automate the acquisition, analysis, archiving, and distribution of satellite earth science data. Both results are applications of Artificial Intelligence planning research to the automatic generation of processing steps for image analysis tasks. First, we have constructed a linear conditional planner (CPed), used to generate conditional processing plans. Second, we have extended an existing hierarchical planning system to make use of durations, resources, and deadlines, thus supporting the automatic generation of processing steps in time and resource-constrained environments.

Preliminary Reports, Memoranda and Technical Notes of the Materials Research Council Summer Conference, La Jolla, California

DTIC Science & Technology

1984-07-01

Faurie U of Illinois 312-996-2141 A.D. Morrison Jet Propulsion Lab 213-354- 7200 A.R. Calawa Lincoln Lab, MIT 617-863-550C Ron Kerber DARPA 202-694...environment can only be assessed following extensive experimentation in space.2 mM Considering the failure of all efforts to suppress, during growth on earth ... earth because of constitutional supercooling effect. For oxide systems, the possibility exists to establish non-wetting configurations and thus to avoid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Byrer, C.W.; Layne, A.W.; Guthrie, H.D.

The U.S. Department of Energy (DOE), at its Morgantown Energy Technology Center, has been involved in natural gas research since the 1970`s. DOE has assessed the potential of gas in coals throughout the U.S. and promoted research and development for recovery and use of methane found in minable and unminable coalbeds. DOE efforts have focused on the use of coal mine methane for regional economic gas self-sufficiency, energy parks, self-help initiatives, and small-power generation. This paper focuses on DOE`s past and present efforts to more effectively and efficiently recover and use this valuable domestic energy source. The Climate Change Actionmore » Plan (CCAP) (1) lists a series of 50 voluntary initiatives designed to reduce greenhouse gas emissions, such as methane from mining operations, to their 1990 levels. Action No. 36 of the CCAP expands the DOE research, development, and demonstration (RD&D) efforts to broaden the range of cost-effective technologies and practices for recovering methane associated with coal mining operations. The major thrust of Action No. 36 is to reduce methane emissions associated with coal mining operations from target year 2000 levels by 1.5 MMT of carbon equivalent. Crosscutting activities in the DOE Natural Gas Program supply the utilization sectors will address RD&D to reduce methane emissions released from various mining operations, focusing on recovery and end use technology systems to effectively drain, capture, and utilize the emitted gas. Pilot projects with industry partners will develop and test the most effective methods and technology systems for economic recovery and utilization of coal mine gas emissions in regions where industry considers efforts to be presently non-economic. These existing RD&D programs focus on near-term gas recovery and gathering systems, gas upgrading, and power generation.« less

Harnessing the Risk-Related Data Supply Chain: An Information Architecture Approach to Enriching Human System Research and Operations Knowledge

NASA Technical Reports Server (NTRS)

Buquo, Lynn; Johnson-Throop, Kathy

2010-01-01

NASA's Human Research Program (HRP) and Space Life Sciences Directorate (SLSD), not unlike many NASA organizations today, struggle with the inherent inefficiencies caused by dependencies on heterogeneous data systems and silos of data and information spread across decentralized discipline domains. The capture of operational and research-based data/information (both in-flight and ground-based) in disparate IT systems impedes the extent to which that data/information can be efficiently and securely shared, analyzed, and enriched into knowledge that directly and more rapidly supports HRP's research-focused human system risk mitigation efforts and SLSD s operationally oriented risk management efforts. As a result, an integrated effort is underway to more fully understand and document how specific sets of risk-related data/information are generated and used and in what IT systems that data/information currently resides. By mapping the risk-related data flow from raw data to useable information and knowledge (think of it as the data supply chain), HRP and SLSD are building an information architecture plan to leverage their existing, shared IT infrastructure. In addition, it is important to create a centralized structured tool to represent risks including attributes such as likelihood, consequence, contributing factors, and the evidence supporting the information in all these fields. Representing the risks in this way enables reasoning about the risks, e.g. revisiting a risk assessment when a mitigation strategy is unavailable, updating a risk assessment when new information becomes available, etc. Such a system also provides a concise way to communicate the risks both within the organization as well as with collaborators. Understanding and, hence, harnessing the human system risk-related data supply chain enhances both organizations' abilities to securely collect, integrate, and share data assets that improve human system research and operations.

Development and validation of a measure of food choice values.

PubMed

Lyerly, Jordan E; Reeve, Charlie L

2015-06-01

Food choice values (FCVs) are factors that individuals consider when deciding which foods to purchase and/or consume. Given the potentially important implications for health, it is critical for researchers to have access to a validated measure of FCV. Though there is an existing measure of FCV, this measure was developed 20 years ago and recent research suggests additional FCVs exist that are not included in this measure. A series of four studies was conducted to develop a new expanded measure of FCV. An eight-factor model of FCV was supported and confirmed. In aggregate, results from the four studies indicate that the measure is content valid, and has internally consistent scales that also demonstrated acceptable temporal stability and convergent validity. In addition, the eight scales of the measures were independent of social desirability, met criteria for measurement invariance across income groups, and predicted dietary intake. The development of this new measure of FCV may be useful for researchers examining FCVs (FCVs) in the future, as well as for use in intervention and prevention efforts targeting dietary choices. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Structure of Psychopathology: Toward an Expanded Quantitative Empirical Model

PubMed Central

Wright, Aidan G.C.; Krueger, Robert F.; Hobbs, Megan J.; Markon, Kristian E.; Eaton, Nicholas R.; Slade, Tim

2013-01-01

There has been substantial recent interest in the development of a quantitative, empirically based model of psychopathology. However, the majority of pertinent research has focused on analyses of diagnoses, as described in current official nosologies. This is a significant limitation because existing diagnostic categories are often heterogeneous. In the current research, we aimed to redress this limitation of the existing literature, and to directly compare the fit of categorical, continuous, and hybrid (i.e., combined categorical and continuous) models of syndromes derived from indicators more fine-grained than diagnoses. We analyzed data from a large representative epidemiologic sample (the 2007 Australian National Survey of Mental Health and Wellbeing; N = 8,841). Continuous models provided the best fit for each syndrome we observed (Distress, Obsessive Compulsivity, Fear, Alcohol Problems, Drug Problems, and Psychotic Experiences). In addition, the best fitting higher-order model of these syndromes grouped them into three broad spectra: Internalizing, Externalizing, and Psychotic Experiences. We discuss these results in terms of future efforts to refine emerging empirically based, dimensional-spectrum model of psychopathology, and to use the model to frame psychopathology research more broadly. PMID:23067258

Defining Attributes and Metrics of Effective Research Mentoring Relationships

PubMed Central

Byars-Winston, Angela; Branchaw, Janet; Hurtado, Sylvia; Eagan, Kevin

2016-01-01

Despite evidence of mentoring’s importance in training researchers, studies to date have not yet determined which mentoring relationships have the most impact and what specific factors in those mentoring relationships contribute to key outcomes, such as the commitment to and persistence in research career paths for emerging researchers from diverse populations. Efforts to broaden participation and persistence in biomedical research careers require an understanding of why and how mentoring relationships work and their impact, not only to research training but also to promoting career advancement. This paper proposes core attributes of effective mentoring relationships, as supported by the literature and suggested by theoretical models of academic persistence. In addition, both existing and developing metrics for measuring the effectiveness of these attributes within mentoring relationships across diverse groups are presented, as well as preliminary data on these metrics from the authors’ work. PMID:27062425

Neural systems implicated in obesity as an addictive disorder: from biological to behavioral mechanisms.

PubMed

Schulte, Erica M; Yokum, Sonja; Potenza, Marc N; Gearhardt, Ashley N

2016-01-01

Contributing factors to obesity have been identified, yet prevention and treatment efforts have had limited long-term success. It has recently been suggested that some individuals may experience an addictive-like response to certain foods, such as losing control over consumption and continued consumption despite negative consequences. In support, shared biological and behavioral features seem to exist between "food addiction" and traditional substance-use disorders. "Food addiction" may be another important contributor to obesity. The current chapter reviews existing literature regarding neural systems implicated similarly in obesity and addiction, discusses unique considerations for addictive-like eating, and proposes directions for future research regarding "food addiction" as an emerging construct for addiction medicine. © 2016 Elsevier B.V. All rights reserved.

A Survey of Challenges in Aerodynamic Exhaust Nozzle Technology for Aerospace Propulsion Applications

NASA Technical Reports Server (NTRS)

Shyne, Rickey J.

2002-01-01

The current paper discusses aerodynamic exhaust nozzle technology challenges for aircraft and space propulsion systems. Technology advances in computational and experimental methods have led to more accurate design and analysis tools, but many major challenges continue to exist in nozzle performance, jet noise and weight reduction. New generations of aircraft and space vehicle concepts dictate that exhaust nozzles have optimum performance, low weight and acceptable noise signatures. Numerous innovative nozzle concepts have been proposed for advanced subsonic, supersonic and hypersonic vehicle configurations such as ejector, mixer-ejector, plug, single expansion ramp, altitude compensating, lobed and chevron nozzles. This paper will discuss the technology barriers that exist for exhaust nozzles as well as current research efforts in place to address the barriers.

Bringing cancer care to the poor: experiences from Rwanda.

PubMed

Shulman, Lawrence N; Mpunga, Tharcisse; Tapela, Neo; Wagner, Claire M; Fadelu, Temidayo; Binagwaho, Agnes

2014-12-01

The knowledge and tools to cure many cancer patients exist in developed countries but are unavailable to many who live in the developing world, resulting in unnecessary loss of life. Bringing cancer care to the poor, particularly to low-income countries, is a great challenge, but it is one that we believe can be met through partnerships, careful planning and a set of guiding principles. Alongside vaccinations, screening and other cancer-prevention efforts, treatment must be a central component of any cancer programme from the start. It is also critical that these programmes include implementation research to determine programmatic efficacy, where gaps in care still exist and where improvements can be made. This article discusses these issues using the example of Rwanda's expanding national cancer programme.

Better drug therapy for the children of Africa: current impediments to success and potential strategies for improvement.

PubMed

Macleod, Stuart M; Finch, Janet K; Macharia, William M; Anabwani, Gabriel M

2013-08-01

A commentary is presented on the urgent need for a comprehensive effort to improve the practice of pediatric therapeutics in Africa. A call for action is addressed to a variety of practitioners internationally, many of whom possess skills that could be fruitfully applied to the improvement of health outcomes for African children. Successful engagement with the many challenges requires the complementary effort of researchers in basic and clinical pharmacology and toxicology, nurses, pharmacists, physicians, clinical pharmacologists, clinical pharmacists, and political leaders and civil servants. While a comprehensive or systematic review of the relevant literature has not been attempted, the authors have highlighted promising initiatives driven by international agencies and academic networks. Two African perspectives are presented to reinforce the prospect of child health gains that can be achieved through consistent pursuit of optimal therapy for conditions such as respiratory infection, diarrhea, malaria, and HIV/AIDS. There is an imperative for development of north-south and south-south partnerships that will amplify current research efforts and mobilize existing knowledge concerning pediatric drugs. The overall goal is a multidisciplinary commitment to making essential medicines available at the right time, the right place, and in the right formulation for African children from infancy to adolescence.

A System Engineering Approach to Strategic Partnership Development: A pilot study with NASA's Orbiting Carbon Observatory-2 (OCO-2) and the National Laboratory for Agriculture and the Environment (NLAE)

NASA Astrophysics Data System (ADS)

Yuen, K.; Chang, G.; Basilio, R. R.; Hatfield, J.; Cox, E. L.

2017-12-01

The prevalence and availability of NASA remote sensing data over the last 40+ years have produced many opportunities for the development of science derived data applications. However, extending and systematically integrating the applications into decision support models and tools have been sporadic and incomplete. Despite efforts among the research communities and external partners, implementation challenges exist and still remain to be addressed. In order to effectively address the systemic gap between the research and applications communities, steps must be taken to effectively bridge that gap: specific goals, a clear plan, and a concerted and diligent effort are needed to produce the desired results. The Orbiting Carbon Observatory-2 (OCO-2) mission sponsored a pilot effort on science data applications with the specific intent of building strategic partnerships, so that organizations and individuals could effectively use OCO-2 data products for application development. The successful partnership with the USDA/ARS National Laboratory for Agriculture and the Environment (NLAE) has laid the foundation for: 1) requirements and lessons for establishing a strategic partnership for application development, 2) building opportunities and growing partnerships for new missions such as OCO-3, and 3) the development of a methodology and approach for integrating application development into a mission life cycle. This presentation will provide an overview of the OCO-2 pilot effort, deliverables, the methodology, implementation, and best practices.

A Multifaceted Mathematical Approach for Complex Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alexander, F.; Anitescu, M.; Bell, J.

2012-03-07

Applied mathematics has an important role to play in developing the tools needed for the analysis, simulation, and optimization of complex problems. These efforts require the development of the mathematical foundations for scientific discovery, engineering design, and risk analysis based on a sound integrated approach for the understanding of complex systems. However, maximizing the impact of applied mathematics on these challenges requires a novel perspective on approaching the mathematical enterprise. Previous reports that have surveyed the DOE's research needs in applied mathematics have played a key role in defining research directions with the community. Although these reports have had significantmore » impact, accurately assessing current research needs requires an evaluation of today's challenges against the backdrop of recent advances in applied mathematics and computing. To address these needs, the DOE Applied Mathematics Program sponsored a Workshop for Mathematics for the Analysis, Simulation and Optimization of Complex Systems on September 13-14, 2011. The workshop had approximately 50 participants from both the national labs and academia. The goal of the workshop was to identify new research areas in applied mathematics that will complement and enhance the existing DOE ASCR Applied Mathematics Program efforts that are needed to address problems associated with complex systems. This report describes recommendations from the workshop and subsequent analysis of the workshop findings by the organizing committee.« less

Tire Crumb Research Study Literature Review / Gap ...

EPA Pesticide Factsheets

In order to more fully understand data gaps in human exposure and toxicity to tire crumb materials, ATSDR, CPSC and EPA undertook a collaborative effort in the form of a scientific literature review and subsequent gaps analysis. The first objective of the Literature Review and Gap Analysis (LRGA) collaboration was to identify the existing body of literature related specifically to human exposure to tire crumb materials through the use of synthetic turf athletic fields and playgrounds. The second objective was to characterize and summarize the relevant data from the scientific literature. The final objective was to review the summary information and identify data gaps to build on the current understanding of the state-of-the-science and inform the development of specific research efforts that would be most impactful in the near-term. Because of the need for additional information, the U.S. Environmental Protection Agency (EPA), the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry (ATSDR), and the U.S. Consumer Product Safety Commission (CPSC) launched a multi-agency action plan to study key environmental human health questions. The Federal Research Action Plan includes numerous activities, including research studies (U.S. EPA, 2016). A key objective of the Action Plan is to identify key knowledge gaps.

Roadmap for Nondestructive Evaluation of Reactor Pressure Vessel Research and Development by the Light Water Reactor Sustainability Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Cyrus M; Nanstad, Randy K; Clayton, Dwight A

2012-09-01

The Department of Energy s (DOE) Light Water Reactor Sustainability (LWRS) Program is a five year effort which works to develop the fundamental scientific basis to understand, predict, and measure changes in materials and systems, structure, and components as they age in environments associated with continued long-term operations of existing commercial nuclear power reactors. This year, the Materials Aging and Degradation (MAaD) Pathway of this program has placed emphasis on emerging Non-Destructive Evaluation (NDE) methods which support these objectives. DOE funded Research and Development (R&D) on emerging NDE techniques to support commercial nuclear reactor sustainability is expected to begin nextmore » year. This summer, the MAaD Pathway invited subject matter experts to participate in a series of workshops which developed the basis for the research plan of these DOE R&D NDE activities. This document presents the results of one of these workshops which are the DOE LWRS NDE R&D Roadmap for Reactor Pressure Vessels (RPV). These workshops made a substantial effort to coordinate the DOE NDE R&D with that already underway or planned by the Electric Power Research Institute (EPRI) and the Nuclear Regulatory Commission (NRC) through their representation at these workshops.« less

Cost, Coverage, and Comparative Effectiveness Research: The Critical Issues for Oncology

PubMed Central

Pearson, Steven D.

2012-01-01

A new national initiative in comparative effectiveness research (CER) is part of a broad and long-term evolution toward greater reliance on scientific evidence in clinical practice and medical policy. But CER has been controversial because of its high profile in the health care reform effort, its instantiation in a prominent new national research institute, and lingering concerns that the ultimate goal of CER is to empower the government and private insurers to reduce health care costs by restricting access to expensive new medical tests and treatments. This article presents an analysis of the policy development behind CER and focuses on its potential impact on insurance coverage and payment for oncology services. By itself, CER will not solve the tension that exists between the goal of innovative, personalized care and the eroding affordability of cancer treatment in the United States. But CER does offer an important opportunity for progress. Oncologists have taken important first steps in acknowledging their responsibility for addressing cost issues; as a professional society, they should now move forward to assume leadership in the effort to integrate clinical evidence with considerations of cost effectiveness to guide clinical practice and insurer policies. PMID:23071229

Forecasting the impact of virtual environment technology on maintenance training

NASA Technical Reports Server (NTRS)

Schlager, Mark S.; Boman, Duane; Piantanida, Tom; Stephenson, Robert

1993-01-01

To assist NASA and the Air Force in determining how and when to invest in virtual environment (VE) technology for maintenance training, we identified possible roles for VE technology in such training, assessed its cost-effectiveness relative to existing technologies, and formulated recommendations for a research agenda that would address instructional and system development issues involved in fielding a VE training system. In the first phase of the study, we surveyed VE developers to forecast capabilities, maturity, and estimated costs for VE component technologies. We then identified maintenance tasks and their training costs through interviews with maintenance technicians, instructors, and training developers. Ten candidate tasks were selected from two classes of maintenance tasks (seven aircraft maintenance and three space maintenance) using five criteria developed to identify types of tasks most likely to benefit from VE training. Three tasks were used as specific cases for cost-benefit analysis. In formulating research recommendations, we considered three aspects of feasibility: technological considerations, cost-effectiveness, and anticipated R&D efforts. In this paper, we describe the major findings in each of these areas and suggest research efforts that we believe will help achieve the goal of a cost-effective VE maintenance training system by the next decade.

A Cutting-Edge Education: Incorporating Nano into the Undergraduate Curricula.

NASA Astrophysics Data System (ADS)

Zenner, Greta M.

2008-03-01

The Interdisciplinary Education Group (IEG) of the Materials Research Science and Engineering Center (MRSEC) on Nanostructured Interfaces at the University of Wisconsin-Madison (UW) develops and uses hands-on, interactive education and outreach materials to engage a variety of audiences in learning about nanotechnology and advanced materials. Many of the education products created are inspired by UW MRSEC research; and faculty, staff, and students regularly contribute to the IEG's work to share nanotechnology with a broader audience. The UW MRSEC has developed numerous teaching modules, labs, and education resources devoted to nanotechnology concepts, and many of these materials have been integrated into key introductory and advanced undergraduate courses at UW and other institutions, including small liberal arts colleges and community colleges. This effort has taken place through both the creation of new courses and the modification of existing courses to include cutting-edge content based on current research and emerging applications in nanotechnology. In this talk, I will present some of the new instructional materials we have developed based on advances in nanoscale science and technology, the implementation and integration of these materials into undergraduate curricula, and an overview of the UW MRSEC education efforts.

NASA's Earth Science Enterprise's Water and Energy Cycle Focus Area

NASA Astrophysics Data System (ADS)

Entin, J. K.

2004-05-01

Understanding the Water and Energy cycles is critical towards improving our understanding of climate change, as well as the consequences of climate change. In addition, using results from water and energy cycle research can help improve water resource management, agricultural efficiency, disaster management, and public health. To address this, NASA's Earth Science Enterprise (ESE) has an end-to-end Water and Energy Cycle Focus Area, which along with the ESE's other five focus areas will help NASA answer key Earth Science questions. In an effort to build upon the pre-existing discipline programs, which focus on precipitation, radiation sciences, and terrestrial hydrology, NASA has begun planning efforts to create an implementation plan for integrative research to improve our understanding of the water and energy cycles. The basics of this planning process and the core aspects of the implementation plan will be discussed. Roadmaps will also be used to show the future direction for the entire focus area. Included in the discussion, will be aspects of the end-to-end nature of the Focus Area that encompass current and potential actives to extend research results to operational agencies to enable improved performance of policy and management decision support systems.

How do we get from cell and animal data to risks for humans from space radiations?

NASA Technical Reports Server (NTRS)

Dicello, J. F.

2002-01-01

After four decades of human exploration in space, many scientists consider the medical consequences from radiation exposures to be the major biological risk associated with long-term missions. This conclusion is based upon results from a research program that has evolved over the past thirty years. Despite the diversity in both opinions and approaches that necessarily arise in research endeavors such as this, a commonality has emerged from our community. We need epidemiological data for humans, animal data in areas where no human data exist, and data on mechanisms to get from animal to humans. We need a programmatic infrastructure that addresses specific goals as well as basic research. These concepts might be deemed overly simplistic and even tautologous were it not for the fact that they are frequently underutilized and even ignored. This article examines the goals, premises, and infrastructures proposed by expert panels and agencies to address radiation risks in space. It is proposed that the required level of effort and the resources available demand a unified, focused international effort that is, at the same time, subjected to rigorous peer review if it is to be successful. There is a plan; let us implement it.

Getting Ready for the Human Phenome Project: The 2012 Forum of the Human Variome Project

PubMed Central

Oetting, William S.; Robinson, Peter N.; Greenblatt, Marc S.; Cotton, Richard G.; Beck, Tim; Carey, John C.; Doelken, Sandra C.; Girdea, Marta; Groza, Tudor; Hamilton, Carol M.; Hamosh, Ada; Kerner, Berit; MacArthur, Jacqueline A. L.; Maglott, Donna R.; Mons, Barend; Rehm, Heidi L.; Schofield, Paul N.; Searle, Beverly A.; Smedley, Damian; Smith, Cynthia L.; Bernstein, Inge Thomsen; Zankl, Andreas; Zhao, Eric Y.

2014-01-01

A forum of the Human Variome Project (HVP) was held as a satellite to the 2012 Annual Meeting of the American Society of Human Genetics in San Francisco, California. The theme of this meeting was “Getting Ready for the Human Phenome Project.” Understanding the genetic contribution to both rare single-gene “Mendelian” disorders and more complex common diseases will require integration of research efforts among many fields and better defined phenotypes. The HVP is dedicated to bringing together researchers and research populations throughout the world to provide the resources to investigate the impact of genetic variation on disease. To this end, there needs to be a greater sharing of phenotype and genotype data. For this to occur, many databases that currently exist will need to become interoperable to allow for the combining of cohorts with similar phenotypes to increase statistical power for studies attempting to identify novel disease genes or causative genetic variants. Improved systems and tools that enhance the collection of phenotype data from clinicians are urgently needed. This meeting begins the HVP’s effort toward this important goal. PMID:23401191

The Environmental Protection Agency's Community-Focused Exposure and Risk Screening Tool (C-FERST) and its potential use for environmental justice efforts.

PubMed

Zartarian, Valerie G; Schultz, Bradley D; Barzyk, Timothy M; Smuts, Marybeth; Hammond, Davyda M; Medina-Vera, Myriam; Geller, Andrew M

2011-12-01

Our primary objective was to provide higher quality, more accessible science to address challenges of characterizing local-scale exposures and risks for enhanced community-based assessments and environmental decision-making. After identifying community needs, priority environmental issues, and current tools, we designed and populated the Community-Focused Exposure and Risk Screening Tool (C-FERST) in collaboration with stakeholders, following a set of defined principles, and considered it in the context of environmental justice. C-FERST is a geographic information system and resource access Web tool under development for supporting multimedia community assessments. Community-level exposure and risk research is being conducted to address specific local issues through case studies. C-FERST can be applied to support environmental justice efforts. It incorporates research to develop community-level data and modeled estimates for priority environmental issues, and other relevant information identified by communities. Initial case studies are under way to refine and test the tool to expand its applicability and transferability. Opportunities exist for scientists to address the many research needs in characterizing local cumulative exposures and risks and for community partners to apply and refine C-FERST.

Female Genital Mutilation in Kenya: are young men allies in social change programmes?

PubMed

Brown, Eleanor; Mwangi-Powell, Faith; Jerotich, Miriam; le May, Victoria

2016-05-01

The Girl Summit held in 2014 aimed to mobilise greater effort to end Female Genital Mutilation (FGM) within a generation, building on a global movement which viewed the practice as a severe form of violence against women and girls and a violation of their rights. The UN, among others, endorse "comprehensive" strategies to end FGM, including legalistic measures, social protection and social communications. FGM is a sensitive issue and difficult to research, and rapid ethnographic methods can use existing relations of trust within social networks to explore attitudes towards predominant social norms which posit FGM as a social necessity. This study used Participatory Ethnographic Evaluation Research (PEER) to understand young men's (18-25 years) perceptions of FGM, demand for FGM among future spouses, and perceptions of efforts to end FGM in a small town in West Pokot, Kenya, where FGM is reported to be high (between 85% to 96%). Twelve PEER researchers were recruited, who conducted two interviews with their friends, generating a total of 72 narrative interviews. The majority of young men who viewed themselves as having a "modern" outlook and with aspirations to marry "educated" women were more likely not to support FGM. Our findings show that young men viewed themselves as valuable allies in ending FGM, but that voicing their opposition to the practice was often difficult. More efforts are needed by multi-stakeholders - campaigners, government and local leaders - to create an enabling environment to voice that opposition. Copyright © 2016 Elsevier Inc. All rights reserved.

The Development of a Veterans Health Administration Emergency Management Research Agenda

PubMed Central

Dobalian, Aram; Claver, Maria; Riopelle, Deborah; Wyte-Lake, Tamar; Canelo, Ismelda

2017-01-01

Introduction: The Veterans Health Administration (VHA), the largest integrated healthcare delivery system in the United States, is charged with ensuring timely access to high-quality care for veterans during disasters, and supporting national, state, local, and tribal emergency management and homeland security efforts. In 2008, the VHA Office of Public Health (OPH) sponsored the first VHA Emergency Management Research Agenda-setting conference to develop research priorities that address the needs of veterans and to position VHA as a national leader in emergency management by having VHA serve as a “laboratory” for the development of evidence-based emergency management practices. Methods: We focused on four steps: #1: Appraising the emergency management research portfolio of VHA-based researchers; #2: Obtaining systematic information on VHA’s role in emergency management and the healthcare needs of veterans during disasters; #3: Based upon gaps between the current research portfolio and the existing evidence base, identifying strategic priorities using a research agenda-setting conference; and #4: Laying the groundwork to foster the conduct of emergency management research within VHA. Results: Identified research priorities included how to prevent and treat behavioral health problems related to a disaster, the efficacy of training programs, crisis communication strategies, workforce resilience, and evacuating veterans from health care facilities. Conclusion: VHA is uniquely situated to answer research questions that cannot be readily addressed in other settings. VHA should partner with other governmental and private entities to build on existing work and establish shared research priorities. PMID:28439447

Semantic Support for Complex Ecosystem Research Environments

NASA Astrophysics Data System (ADS)

Klawonn, M.; McGuinness, D. L.; Pinheiro, P.; Santos, H. O.; Chastain, K.

2015-12-01

As ecosystems come under increasing stresses from diverse sources, there is growing interest in research efforts aimed at monitoring, modeling, and improving understanding of ecosystems and protection options. We aimed to provide a semantic infrastructure capable of representing data initially related to one large aquatic ecosystem research effort - the Jefferson project at Lake George. This effort includes significant historical observational data, extensive sensor-based monitoring data, experimental data, as well as model and simulation data covering topics including lake circulation, watershed runoff, lake biome food webs, etc. The initial measurement representation has been centered on monitoring data and related provenance. We developed a human-aware sensor network ontology (HASNetO) that leverages existing ontologies (PROV-O, OBOE, VSTO*) in support of measurement annotations. We explicitly support the human-aware aspects of human sensor deployment and collection activity to help capture key provenance that often is lacking. Our foundational ontology has since been generalized into a family of ontologies and used to create our human-aware data collection infrastructure that now supports the integration of measurement data along with simulation data. Interestingly, we have also utilized the same infrastructure to work with partners who have some more specific needs for specifying the environmental conditions where measurements occur, for example, knowing that an air temperature is not an external air temperature, but of the air temperature when windows are shut and curtains are open. We have also leveraged the same infrastructure to work with partners more interested in modeling smart cities with data feeds more related to people, mobility, environment, and living. We will introduce our human-aware data collection infrastructure, and demonstrate how it uses HASNetO and its supporting SOLR-based search platform to support data integration and semantic browsing. Further we will present learnings from its use in three relatively diverse large ecosystem research efforts and highlight some benefits and challenges related to our semantically-enhanced foundation.

Adapting Preclinical Benchmarks for First-in-Human Trials of Human Embryonic Stem Cell-Based Therapies.

PubMed

Barazzetti, Gaia; Hurst, Samia A; Mauron, Alexandre

2016-08-01

: As research on human embryonic stem cell (hESC)-based therapies is moving from the laboratory to the clinic, there is an urgent need to assess when it can be ethically justified to make the step from preclinical studies to the first protocols involving human subjects. We examined existing regulatory frameworks stating preclinical requirements relevant to the move to first-in-human (FIH) trials and assessed how they may be applied in the context of hESC-based interventions to best protect research participants. Our findings show that some preclinical benchmarks require rethinking (i.e., identity, purity), while others need to be specified (i.e., potency, viability), owing to the distinctive dynamic heterogeneity of hESC-based products, which increases uncertainty and persistence of safety risks and allows for limited predictions of effects in vivo. Rethinking or adaptation of how to apply preclinical benchmarks in specific cases will be required repeatedly for different hESC-based products. This process would benefit from mutual learning if researchers included these components in the description of their methods in publications. To design translational research with an eye to protecting human participants in early trials, researchers and regulators need to start their efforts at the preclinical stage. Existing regulatory frameworks for preclinical research, however, are not really adapted to this in the case of stem cell translational medicine. This article reviews existing regulatory frameworks for preclinical requirements and assesses how their underlying principles may best be applied in the context of human embryonic stem cell-based interventions for the therapy of Parkinson's disease. This research will help to address the question of when it is ethically justified to start first-in-human trials in stem cell translational medicine. ©AlphaMed Press.

Climate Change and Public Health Surveillance: Toward a Comprehensive Strategy.

PubMed

Moulton, Anthony Drummond; Schramm, Paul John

Climate change poses a host of serious threats to human health that robust public health surveillance systems can help address. It is unknown, however, whether existing surveillance systems in the United States have adequate capacity to serve that role, nor what actions may be needed to develop adequate capacity. Our goals were to review efforts to assess and strengthen the capacity of public health surveillance systems to support health-related adaptation to climate change in the United States and to determine whether additional efforts are warranted. Building on frameworks issued by the Intergovernmental Panel on Climate Change and the Centers for Disease Control and Prevention, we specified 4 core components of public health surveillance capacity relevant to climate change health threats. Using standard methods, we next identified and analyzed multiple assessments of the existing, relevant capacity of public health surveillance systems as well as attempts to improve that capacity. We also received information from selected national public health associations. Multiple federal, state, and local public health agencies, professional associations, and researchers have made valuable, initial efforts to assess and strengthen surveillance capacity. These efforts, however, have been made by entities working independently and without the benefit of a shared conceptual framework or strategy. Their principal focus has been on identifying suitable indicators and data sources largely to the exclusion of other core components of surveillance capacity. A more comprehensive and strategic approach is needed to build the public health surveillance capacity required to protect the health of Americans in a world of rapidly evolving climate change. Public health practitioners and policy makers at all levels can use the findings and issues reviewed in this article as they lead design and execution of a coordinated, multisector strategic plan to create and sustain that capacity.

Climate Change and Public Health Surveillance: Toward a Comprehensive Strategy

PubMed Central

Moulton, Anthony Drummond; Schramm, Paul John

2017-01-01

Context Climate change poses a host of serious threats to human health that robust public health surveillance systems can help address. It is unknown, however, whether existing surveillance systems in the United States have adequate capacity to serve that role, nor what actions may be needed to develop adequate capacity. Objective Our goals were to review efforts to assess and strengthen the capacity of public health surveillance systems to support health-related adaptation to climate change in the United States and to determine whether additional efforts are warranted. Methods Building on frameworks issued by the Intergovernmental Panel on Climate Change and the Centers for Disease Control and Prevention, we specified 4 core components of public health surveillance capacity relevant to climate change health threats. Using standard methods, we next identified and analyzed multiple assessments of the existing, relevant capacity of public health surveillance systems as well as attempts to improve that capacity. We also received information from selected national public health associations. Findings Multiple federal, state, and local public health agencies, professional associations, and researchers have made valuable, initial efforts to assess and strengthen surveillance capacity. These efforts, however, have been made by entities working independently and without the benefit of a shared conceptual framework or strategy. Their principal focus has been on identifying suitable indicators and data sources largely to the exclusion of other core components of surveillance capacity. Conclusions A more comprehensive and strategic approach is needed to build the public health surveillance capacity required to protect the health of Americans in a world of rapidly evolving climate change. Public health practitioners and policy makers at all levels can use the findings and issues reviewed in this article as they lead design and execution of a coordinated, multisector strategic plan to create and sustain that capacity. PMID:28169865

Powering Up: Assessing the growing municipal energy resilience building efforts in North America

NASA Astrophysics Data System (ADS)

Schimmelfing, Kara

Energy related shortages and price volatilities can impact all levels of society. With coming fossil fuel depletion related to peak oil, it is expected these shortages and volatilities will increase in frequency, duration, and intensity. Resilience building is a strategy to minimize the effects of these events by modifying systems so they are less impacted and/or recover more quickly from disruptive events. Resilience building is being used, particularly at the municipal scale, to prepare for these coming energy related changes. These municipal efforts have only been in existence for five to ten years, and full implementation is still in progress. Little evaluation has been done of these municipal efforts to date, particularly in North America. Despite this, it is important to begin to assess the effectiveness of these efforts now. As a result, future efforts can be redirected to address weak areas and that lessons learned by vanguard communities can be applied in other communities attempting to build energy resilience in the future. This thesis involved the creation of a hybrid framework to evaluate municipal energy resilience building efforts. The framework drew primarily from planning process and factors identified as important to build resilience in social-ecological systems. It consisted of the following categories to group resilience building efforts: Economy, Resource Systems & Infrastructure, Public Awareness, Social Services, Transportation, Built Environment, and Natural Environment. Within these categories the following process steps should be observed: Context, Goals, Needs, Processes, and Outcomes. This framework was then tested through application to four case-study communities (Bloomington, IN, Hamilton, ON, Oakland, CA, Victoria, BC) currently pursuing energy resilience building efforts in North America. This qualitative research involved document analysis primarily of municipal documents related to energy planning efforts. Supplementary interviews were also conducted to verify the findings from the documents and illuminate anything not captured by them. Once data was collected, categorized and analyzed using the framework, comparisons were made between case-studies. Results showed the framework to be a successful, but time consuming, tool for assessing municipal energy resilience building. Four revisions are recommended for the framework before further research. Analysis of the case study communities' efforts also identified five factors for recommended for other communities attempting energy resilience planning at the municipal scale: consistent support from within the municipality, integration and information sharing, presence of key resources, access to information on energy use, and a two-tier planning process. Ultimately, as this is a preliminary attempt to address a young and growing area of municipal effort, there are many avenues for further research to build on the work of this thesis.

Effort Gains in Occupational Teams - The Effects of Social Competition and Social Indispensability.

PubMed

Hertel, Guido; Nohe, Christoph; Wessolowski, Katrin; Meltz, Oliver; Pape, Justina C; Fink, Jonas; Hüffmeier, Joachim

2018-01-01

Laboratory research has demonstrated social competition and social indispensability as potential triggers of effort gains in teams as compared to working alone. However, it is unclear whether such effects are also relevant for existing occupational teams, collaborating for longer time intervals and achieving meaningful outcomes. We assumed that social indispensability effects are prevalent and stable in occupational teams, whereas social competition effects should mainly be effective in the beginning of teamwork and fade out over time. Hypotheses were confirmed in two studies using within-subjects designs with employees recruited via an online panel (Study 1, N = 137) and in software development companies (Study 2, N = 70). By means of the Event Reconstruction Method, participants re-experienced specific events from past working days (three events working alone, three teamwork events), and rated their effort separately for these events. In both studies, multilevel analyses revealed significant effort gains in teams when event-specific social indispensability was high. These effects were mediated by positive mood and perceived task meaningfulness, and additionally qualified by employees' preference for teamwork. In contrast, motivating effects due to event-specific social competition were only observed for teams with short as compared to long team tenure in Study 2.

Models and theories of prescribing decisions: A review and suggested a new model

PubMed Central

Mohaidin, Zurina

2017-01-01

To date, research on the prescribing decisions of physician lacks sound theoretical foundations. In fact, drug prescribing by doctors is a complex phenomenon influenced by various factors. Most of the existing studies in the area of drug prescription explain the process of decision-making by physicians via the exploratory approach rather than theoretical. Therefore, this review is an attempt to suggest a value conceptual model that explains the theoretical linkages existing between marketing efforts, patient and pharmacist and physician decision to prescribe the drugs. The paper follows an inclusive review approach and applies the previous theoretical models of prescribing behaviour to identify the relational factors. More specifically, the report identifies and uses several valuable perspectives such as the ‘persuasion theory - elaboration likelihood model’, the stimuli–response marketing model’, the ‘agency theory’, the theory of planned behaviour,’ and ‘social power theory,’ in developing an innovative conceptual paradigm. Based on the combination of existing methods and previous models, this paper suggests a new conceptual model of the physician decision-making process. This unique model has the potential for use in further research. PMID:28690701

Beyond PARR - PMEL's Integrated Data Management Strategy

NASA Astrophysics Data System (ADS)

Burger, E. F.; O'Brien, K.; Manke, A. B.; Schweitzer, R.; Smith, K. M.

2016-12-01

NOAA's Pacific Marine Environmental Laboratory (PMEL) hosts a wide range of scientific projects that span a number of scientific and environmental research disciplines. Each of these 14 research projects have their own data streams that are as diverse as the research. With its requirements for public access to federally funded research results and data, the 2013 White House Office of Science and Technology memo on Public Access to Research Results (PARR) changed the data management landscape for Federal agencies. In 2015, with support from the PMEL Director, Dr. Christopher Sabine, PMEL's Science Data Integration Group (SDIG) initiated a multi-year effort to formulate and implement an integrated data-management strategy for PMEL research efforts. Instead of using external requirements, such as PARR, to define our approach, we focussed on strategies to provide PMEL science projects with a unified framework for data submission, interoperable data access, data storage, and easier data archival to National Data Centers. This improves data access to PMEL scientists, their collaborators, and the public, and also provides a unified lab framework that allows our projects to meet their data management objectives, as well as those required by the PARR. We are implementing this solution in stages that allows us to test technology and architecture choices before comitting to a large scale implementation. SDIG developers have completed the first year of development where our approach is to reuse and leverage existing frameworks and standards. This presentation will describe our data management strategy, explain our phased implementation approach, the software and framework choices, and how these elements help us meet the objectives of this strategy. We will share the lessons learned in dealing with diverse and complex datasets in this first year of implementation and how these outcomes will shape our decisions for this ongoing effort. The data management capabilities now available to scientific projects, and other services being developed to manage and preserve PMEL's scientific data assets for our researchers, their collaborators, and future generations, will be described.

The Zooniverse: Cutting Edge Scientific Research in the Classroom

NASA Astrophysics Data System (ADS)

Borden, K. A.; Whyte, L. F.; Smith, A.; Tarnoff, A.; Schmitt, H.

2012-12-01

Increasingly scientists and researchers from a multitude of disciplines are finding themselves inundated with more data than they could possibly interpret in a lifetime. Computers can be used entirely or partially for some data analysis; but there are some tasks that are currently best suited to human eyes, ears and brains. Zooniverse (www.zooniverse.org) invites members of the public to help researchers analyze and interpret data. To date, hundreds of thousands of volunteers have been involved in classifying images, interpreting sounds and transcribing texts. Zooniverse citizen scientists are providing valuable analyses across a variety of fields, from the hunt for exoplanets in Planet Hunters (planethunters.org) to the transcription of Greek papyri in Ancient Lives (ancientlives.org). Multiple academic publications have resulted from the combined efforts of the Zooniverse community and science teams demonstrating that citizen science is more than ever becoming a well-established method of doing research. Unlike most research projects the data, analysis and interactions with the science teams have an established and visible online presence through the project website and related discussion sites and blogs. These in themselves provide a valuable classroom resource, an opportunity for free and easy access to cutting edge scientific research. Anecdotal evidence exists that teacher can and already do use Zooniverse projects. By providing a rich and varied scaffolding to accompany the Zooniverse projects the opportunity exists for bringing citizen scientists to a wider classroom audience. An audience that may include non-specialist teachers, who require additional support to deliver challenging content, or time strapped educators who haven't the time to develop their own accompanying resources to weave Zooniverse projects into their lessons. During the session we will discuss the recent Zooniverse projects specifically designed to support and promote classroom adoption locally, within the Chicago Public School (CPS) system and nationally within the United States. Introducing ZooTeach, a website where educators may share and search for lesson plans, activities, and resources. Beyond a simple lesson plan repository, ZooTeach is a community where educators are encouraged to modify, comment on, and otherwise actively participate in the educational efforts of Zooniverse. Teacher workshops run at Adler have and will continue to have the dual effect of promoting the Zooniverse and it's educational effort while increasing the pool of resources available nationally via ZooTeach. In house developed teacher guides and interactive tools allowing for the collection and manipulation of data will further enhance the classroom education experience and further lower the bar for entry into the world of citizen science.

Process-driven information management system at a biotech company: concept and implementation.

PubMed

Gobbi, Alberto; Funeriu, Sandra; Ioannou, John; Wang, Jinyi; Lee, Man-Ling; Palmer, Chris; Bamford, Bob; Hewitt, Robin

2004-01-01

While established pharmaceutical companies have chemical information systems in place to manage their compounds and the associated data, new startup companies need to implement these systems from scratch. Decisions made early in the design phase usually have long lasting effects on the expandability, maintenance effort, and costs associated with the information management system. Careful analysis of work and data flows, both inter- and intradepartmental, and identification of existing dependencies between activities are important. This knowledge is required to implement an information management system, which enables the research community to work efficiently by avoiding redundant registration and processing of data and by timely provision of the data whenever needed. This paper first presents the workflows existing at Anadys, then ARISE, the research information management system developed in-house at Anadys. ARISE was designed to support the preclinical drug discovery process and covers compound registration, analytical quality control, inventory management, high-throughput screening, lower throughput screening, and data reporting.

Creating the future: IAIMS planning premises at the University of Washington.

PubMed Central

Fuller, S S

1992-01-01

In September 1990, the University of Washington (UW) received a Phase I IAIMS Planning Grant from the National Library of Medicine and embarked upon a planning process involving the entire health sciences center. As a result of our relatively late entry into IAIMS planning, we have been able to learn from the experiences of other health sciences centers and to leverage our existing institutional efforts. Consequently, our progress has been rapid, and in a little over a year, we drafted a long-range plan and embarked on several related research and development projects. The hallmarks of our planning process include careful study of both the UW institutional environment and the experiences of other IAIMS institutions throughout the United States; broad, interdisciplinary participation of faculty, librarians, and administrators; an intensive educational process; a focus on people rather than technology; and, above all, leveraging of existing institutional and research projects that support our vision for the future. PMID:1326372

Open-source platforms for navigated image-guided interventions.

PubMed

Ungi, Tamas; Lasso, Andras; Fichtinger, Gabor

2016-10-01

Navigation technology is changing the clinical standards in medical interventions by making existing procedures more accurate, and new procedures possible. Navigation is based on preoperative or intraoperative imaging combined with 3-dimensional position tracking of interventional tools registered to the images. Research of navigation technology in medical interventions requires significant engineering efforts. The difficulty of developing such complex systems has been limiting the clinical translation of new methods and ideas. A key to the future success of this field is to provide researchers with platforms that allow rapid implementation of applications with minimal resources spent on reimplementing existing system features. A number of platforms have been already developed that can share data in real time through standard interfaces. Complete navigation systems can be built using these platforms using a layered software architecture. In this paper, we review the most popular platforms, and show an effective way to take advantage of them through an example surgical navigation application. Copyright © 2016 Elsevier B.V. All rights reserved.

Circulation Control in NASA's Vehicle Systems

NASA Technical Reports Server (NTRS)

Rich, Paul; McKinley, Bob; Jones, Greg

2005-01-01

Specific to the application of any technology to a vehicle, such as circulation control, it is important to understand the process that NASA is using to set its direction in research and development. To see how circulation control fits into any given NASA program requires the reader to understand NASA's Vehicle Systems (VS) Program. The VS Program recently celebrated its first year of existence with an annual review - an opportunity to look back on accomplishments, solicit feedback, expand national advocacy and support for the program, and recognize key contributions. Since its formation last year, Vehicle Systems has coordinated seven existing entities in a streamlined aeronautics research effort. It invests in vehicle technologies to protect the environment, make air travel more accessible and affordable for Americans, enable exploration through new aerospace missions, and augment national security. This past year has seen a series of valuable partnerships with industry, academia, and government agencies to make crucial aeronautics advances and assure America s future in flight.

Simulating human behavior for national security human interactions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernard, Michael Lewis; Hart, Dereck H.; Verzi, Stephen J.

2007-01-01

This 3-year research and development effort focused on what we believe is a significant technical gap in existing modeling and simulation capabilities: the representation of plausible human cognition and behaviors within a dynamic, simulated environment. Specifically, the intent of the ''Simulating Human Behavior for National Security Human Interactions'' project was to demonstrate initial simulated human modeling capability that realistically represents intra- and inter-group interaction behaviors between simulated humans and human-controlled avatars as they respond to their environment. Significant process was made towards simulating human behaviors through the development of a framework that produces realistic characteristics and movement. The simulated humansmore » were created from models designed to be psychologically plausible by being based on robust psychological research and theory. Progress was also made towards enhancing Sandia National Laboratories existing cognitive models to support culturally plausible behaviors that are important in representing group interactions. These models were implemented in the modular, interoperable, and commercially supported Umbra{reg_sign} simulation framework.« less

Design of the iSTAR International STudy on Astronomy Reasoning

NASA Astrophysics Data System (ADS)

Tatge, Coty B.; Slater, Stephanie J.

2015-01-01

Beginning in 2013, a small international collaborative of discipline-based astronomy education researchers began to build the foundation to start the International STudy on Astronomy Reasoning Project, known simply as iSTAR. The project was a direct result of the inability of existing large international investigations into the learning of science, such as the TIMSS and PISA studies, to provide actionable intelligence on either strengths or weaknesses of astronomy teaching across the world. This is not because those studies were flawed; rather, they focused on the general characteristics of teaching and learning across all sciences. Prior to the iSTAR effort, there has been no systematic effort to measure individual's conceptual astronomy understanding across the globe. The goal of studying a widely dispersed international sample is to identify cultural subpopulations that do not conform to our existing knowledge of student misconceptions, highlighting unexpected cultural or educational practices that hint at alternative, and perhaps more effective, means of instruction. As a first step, we are carefully translating the Test Of Astronomy STandards - TOAST multiple-choice assessment instrument and carefully attending to nuances that occur during the translation process as cultural clues to differences in the teaching and learning of astronomy. We are actively welcoming and seeking international partners in this work through the CAPERteam.com website and at https://www.surveymonkey.com/s/iSTAR-Registration . This project is sponsored and managed by the CAPER Center for Astronomy & Physics Education Research in collaboration with members of the International Astronomical Union-Commission 46.

Improving the Usability of Integrated Assessment for Adaptation Practice: Insights from the U.S. Southeast Energy Sector

DOE Office of Scientific and Technical Information (OSTI.GOV)

de Bremond, Ariane; Preston, Benjamin; Rice, Jennie S.

2014-10-01

Energy systems comprise a key sector of the U.S. economy, and one that has been identified as potentially vulnerable to the effects of climate variability and change. However, understanding of adaptation processes in energy companies and private entities more broadly is limited. It is unclear, for example, the extent to which energy companies are well-served by existing knowledge and tools emerging from the impacts, adaptation and vulnerability (IAV) and integrated assessment modeling (IAM) communities and/or what experiments, analyses, and model results have practical utility for informing adaptation in the energy sector. As part of a regional IAM development project, wemore » investigated available evidence of adaptation processes in the energy sector, with a particular emphasis on the U.S. Southeast and Gulf Coast region. A mixed methods approach of literature review and semi-structured interviews with key informants from energy utilities was used to compare existing knowledge from the IAV community with that of regional stakeholders. That comparison revealed that much of the IAV literature on the energy sector is climate-centric and therefore disconnected from the more integrated decision-making processes and institutional perspectives of energy utilities. Increasing the relevance of research and assessment for the energy sector will necessitate a greater investment in integrated assessment and modeling efforts that respond to practical decision-making needs as well as greater collaboration between energy utilities and researchers in the design, execution, and communication of those efforts.« less

Culture and cognition in health systems change.

PubMed

Evans, Jenna M; Baker, G Ross; Berta, Whitney; Barnsley, Jan

2015-01-01

Large-scale change involves modifying not only the structures and functions of multiple organizations, but also the mindsets and behaviours of diverse stakeholders. This paper focuses on the latter: the informal, less visible, and often neglected psychological and social factors implicated in change efforts. The purpose of this paper is to differentiate between the concepts of organizational culture and mental models, to argue for the value of applying a shared mental models (SMM) framework to large-scale change, and to suggest directions for future research. The authors provide an overview of SMM theory and use it to explore the dynamic relationship between culture and cognition. The contributions and limitations of the theory to change efforts are also discussed. Culture and cognition are complementary perspectives, providing insight into two different levels of the change process. SMM theory draws attention to important questions that add value to existing perspectives on large-scale change. The authors outline these questions for future research and argue that research and practice in this domain may be best served by focusing less on the potentially narrow goal of "achieving consensus" and more on identifying, understanding, and managing cognitive convergences and divergences as part of broader research and change management programmes. Drawing from both cultural and cognitive paradigms can provide researchers with a more complete picture of the processes by which coordinated action are achieved in complex change initiatives in the healthcare domain.

Migration stopover ecology of western avian populations: A southwestern migration workshop

USGS Publications Warehouse

Skagen, Susan K.; Melcher, Cynthia P.; Hazelwood, Rob

2004-01-01

Workshop participants discussed a coordinated approach for addressing immediate research needs regarding migration patterns and crucial stopover sites and types. They envisioned a three­-tiered, coordinated approach: (1) long-term research to address effects of climate change and other large-scale patterns, (2) intensive, short-term survey and monitoring efforts using a stratified random design within habitats of interest to elucidate regional patterns of distribution and habitat use, and (3) research conducted at existing survey and banding sites to address more in-depth questions (e.g., rates of lipid deposition, microhabitat use, isotope analyses). There was considerable interest in developing common research proposals to blend the broad expertise represented at this workshop. A second meeting is recommended to build on the momentum of these discussions, to facilitate collaborations, and further the goals of integrated approaches to broadscale research on migration stopover ecology. 

Through the minefield: teaching climate change in a misinformation-rich environment

NASA Astrophysics Data System (ADS)

Bedford, D. P.; Cook, J.; Schuenemann, K. C.; Mandia, S. A.; Cowtan, K.; Nuccitelli, D.

2016-12-01

It is now widely accepted that students enter science classrooms with their own, often erroneous, pre-existing models of basic scientific concepts. These misconceptions can interfere with student learning. However, the science of climate change is perhaps distinctive in that a deliberate effort has been undertaken by a variety of individuals and institutions to promulgate and perpetuate misconceptions. Both formal and informal efforts to communicate the science of climate change must therefore contend with the effects of these misconceptions, which may be passionately held and in strong opposition to the findings of peer-reviewed research. This presentation reports on the current state of research on misinformation and misconceptions; identifies common mistakes made in attempting to address misconceptions; and details a model which can help to avoid making most, if not all, of these common mistakes. In sum, research in cognitive psychology has shown that misconceptions are extraordinarily difficult to remove, with individuals commonly rejecting information that does not fit with their existing mental models. Attempts to address misconceptions directly can backfire if too much emphasis is placed on the misconception (i.e. leading with the myth) or by reinforcing the misconception at the expense of more accurate explanations (the familiarity backfire effect). Thus, a preferred approach involves a "myth sandwich" of facts followed by myth, followed by an explanation of how the myth distorts the facts. The misconception is therefore sandwiched between facts. This approach has been tested in a widely subscribed MOOC (Denial 101X, by Cook et al., 2015), and a textbook (Bedford and Cook, 2016). This presentation provides fundamental background on effective climate change myth debunking, and will include preliminary data regarding the efficacy of the "myth sandwich" approach.

Publication bias and the limited strength model of self-control: has the evidence for ego depletion been overestimated?

PubMed

Carter, Evan C; McCullough, Michael E

2014-01-01

Few models of self-control have generated as much scientific interest as has the limited strength model. One of the entailments of this model, the depletion effect, is the expectation that acts of self-control will be less effective when they follow prior acts of self-control. Results from a previous meta-analysis concluded that the depletion effect is robust and medium in magnitude (d = 0.62). However, when we applied methods for estimating and correcting for small-study effects (such as publication bias) to the data from this previous meta-analysis effort, we found very strong signals of publication bias, along with an indication that the depletion effect is actually no different from zero. We conclude that until greater certainty about the size of the depletion effect can be established, circumspection about the existence of this phenomenon is warranted, and that rather than elaborating on the model, research efforts should focus on establishing whether the basic effect exists. We argue that the evidence for the depletion effect is a useful case study for illustrating the dangers of small-study effects as well as some of the possible tools for mitigating their influence in psychological science.

Biology and Conservation of the Taiwanese Humpback Dolphin, Sousa chinensis taiwanensis.

PubMed

Wang, John Y; Riehl, Kimberly N; Klein, Michelle N; Javdan, Shiva; Hoffman, Jordan M; Dungan, Sarah Z; Dares, Lauren E; Araújo-Wang, Claryana

2016-01-01

The humpback dolphins of the eastern Taiwan Strait were first discovered scientifically in 2002 and since then have received much research attention. We reviewed all information published in peer-reviewed scientific journals on these dolphins and where appropriate and available, peer-reviewed scientific workshop reports and graduate theses were also examined. Recent evidence demonstrated that this population warranted recognition as a subspecies, Sousa chinensis taiwanensis. It is found in a highly restricted and linear strip of coastal waters along central western Taiwan. Numbering fewer than 80 individuals and declining, five main threats (fisheries interactions, habitat loss and degradation, loss of freshwater to estuaries within their habitat, air and water pollution, and noise) threaten the future existence of this subspecies. These dolphins have cultural and religious importance and boast the highest level of legal protection for wildlife in Taiwan. However, despite enormous efforts by local and international non-governmental groups urging immediate conservation actions, there have been no real government efforts to mitigate any existing threats; instead, some of these threats have worsened. Based on recent studies, we suggest the IUCN Red List status be revised to Critically Endangered CR 2a(ii); D for the subspecies. © 2016 Elsevier Ltd. All rights reserved.

Monaural and binaural processing of complex waveforms

NASA Astrophysics Data System (ADS)

Trahiotis, Constantine; Bernstein, Leslie R.

1992-01-01

Our research concerned the manners by which the monaural and binaural auditory systems process information in complex sounds. Substantial progress was made in three areas, consistent with the ojectives outlined in the original proposal. (1) New electronic equipment, including a NeXT computer was purchased, installed and interfaced with the existing laboratory. Software was developed for generating the necessary complex digital stimuli and for running behavioral experiments utilizing those stimuli. (2) Monaural experiments showed that the CMR is not obtained successively and is reduced or non-existent when the flanking bands are pulsed rather than presented continuously. Binaural investigations revealed that the detectability of a tonal target in a masking level difference paradigm could be degraded by the presence of a spectrally remote interfering tone. (3) In collaboration with Dr. Richard Stem, theoretical efforts included the explication and evaluation of a weighted-image model of binaural hearing, attempts to extend the Stern-Colbum position-variable model to account for many crucial lateralization and localization data gathered over the past 50 years, and the continuation of efforts to incorporate into a general model notions that lateralization and localization of spectrally-rich stimuli depend upon the patterns of neural activity within a plane defined by frequency and interaural delay.

Overcoming Barriers in Kidney Health-Forging a Platform for Innovation.

PubMed

Linde, Peter G; Archdeacon, Patrick; Breyer, Matthew D; Ibrahim, Tod; Inrig, Jula K; Kewalramani, Reshma; Lee, Celeste Castillo; Neuland, Carolyn Y; Roy-Chaudhury, Prabir; Sloand, James A; Meyer, Rachel; Smith, Kimberly A; Snook, Jennifer; West, Melissa; Falk, Ronald J

2016-07-01

Innovation in kidney diseases is not commensurate with the effect of these diseases on human health and mortality or innovation in other key therapeutic areas. A primary cause of the dearth in innovation is that kidney diseases disproportionately affect a demographic that is largely disenfranchised, lacking sufficient advocacy, public attention, and funding. A secondary and likely consequent cause is that the existing infrastructure supporting nephrology research pales in comparison with those for other internal medicine specialties, especially cardiology and oncology. Citing such inequities, however, is not enough. Changing the status quo will require a coordinated effort to identify and redress the existing deficits. Specifically, these deficits relate to the need to further develop and improve the following: understanding of the disease mechanisms and pathophysiology, patient engagement and activism, clinical trial infrastructure, and investigational clinical trial designs as well as coordinated efforts among critical stakeholders. This paper identifies potential solutions to these barriers, some of which are already underway through the Kidney Health Initiative. The Kidney Health Initiative is unique and will serve as a current and future platform from which to overcome these barriers to innovation in nephrology. Copyright © 2016 by the American Society of Nephrology.

Increasing resiliency to natural hazards - A strategic plan for the Multi-Hazards Demonstration Project in Southern California

USGS Publications Warehouse

Jones, Lucy; Bernknopf, Richard; Cannon, Susan; Cox, Dale A.; Gaydos, Len; Keeley, Jon; Kohler, Monica; Lee, Homa; Ponti, Daniel; Ross, Stephanie L.; Schwarzbach, Steven; Shulters, Michael; Ward, A. Wesley; Wein, Anne

2007-01-01

The U.S. Geological Survey (USGS) is initiating a new project designed to improve resiliency to natural hazards in southern California through the application of science to community decision making and emergency response. The Multi-Hazards Demonstration Project will assist the region’s communities to reduce their risk from natural hazards by directing new and existing research towards the community’s needs, improving monitoring technology, producing innovative products, and improving dissemination of the results. The natural hazards to be investigated in this project include coastal erosion, earthquakes, floods, landslides, tsunamis, and wildfires.Americans are more at risk from natural hazards now than at any other time in our Nation’s history. Southern California, in particular, has one of the Nation’s highest potentials for extreme catastrophic losses due to natural hazards, with estimates of expected losses exceeding $3 billion per year. These losses can only be reduced through the decisions of the southern California community itself. To be effective, these decisions must be guided by the best information about hazards, risk, and the cost-effectiveness of mitigation technologies. The USGS will work with collaborators to set the direction of the research and to create multi-hazard risk frameworks where communities can apply the results of scientific research to their decision-making processes. Partners include state, county, city, and public-lands government agencies, public and private utilities, companies with a significant impact and presence in southern California, academic researchers, the Federal Emergency Management Agency (FEMA), National Oceanic and Atmospheric Administration (NOAA), and local emergency response agencies.Prior to the writing of this strategic plan document, three strategic planning workshops were held in February and March 2006 at the USGS office in Pasadena to explore potential relationships. The goal of these planning sessions was to determine the external organizations’ needs for mitigation efforts before potential natural hazard events, and response efforts during and after the event. On the basis of input from workshop participants, four priority areas were identified for future research to address. They are (1) helping decision makers design planning scenarios, (2) improving upon the mapping of multiple hazards in urban areas, (3) providing real-time information from monitoring networks, and (4) integrating information in a risk and decision-making analysis. Towards this end, short-term and out-year goals have been outlined with the priorities in mind.First-year goals are (1) to engage the user community to establish the structures and processes for communications and interactions, (2) to develop a program to create scenarios of anticipated disasters, beginning in the first year with a scenario of a southern San Andreas earthquake that triggers secondary hazards, (3) to compile existing datasets of geospatial data, and (4) to target research efforts to support more complete and robust products in future years. Both the first-year and out-year goals have been formulated around a working-group structure that builds on existing research strengths within the USGS. The project is intended to demonstrate how developments in methodology and products can lead to improvement in our management of natural hazards in an urban environment for application across the Nation.

The neurobiological impact of postpartum maternal depression: prevention and intervention approaches

PubMed Central

Scaramella, Laura; Zeanah, Charles H.

2016-01-01

The lasting negative impact of postpartum depression (PPD) on offspring is well established. PDD appears to impact neurobiological pathways linked to socio-emotional regulation, cognitive and executive function, and physiologic stress response systems, systems also associated with toxic stress and negative health trajectories across the life course. Perinatal depression is expected to have significant consequences for offspring given the shared biological processes during pregnancy and the subsequent primacy of the early maternal-child relationship in shaping the child’s neurobiological development. A substantial body of literature has examined prevention and intervention efforts during the prenatal period, including the challenges associated with the medication use during pregnancy. 1,2 Recognizing the expansive nature of the existing literature, this review take a novel focus, specifically examining the current state of research defining the effect of universal, selected and indicated interventions for PDD on infant neurodevelopment. This focus was selected because of the unique nature of this time-period for the interaction of maternal psychopathology and infant development, acknowledging that both prenatal and parental depression at later developmental times points can influence child outcomes. We begin by providing a general overview of PPD and the rapid neurodevelopmental changes occurring during the first years of life. Building upon this foundation, we then discuss the specific evidence linking postpartum depression to neurobiological consequences in the offspring. We focus on the development of neural pathways with established associations those aspects of maternal caregiving most impacted by depression, including feeding and nutrition, sleep, health monitoring, play and language, and maternal sensitivity and engagement. Lastly, we discuss specific evidence related to the efficacy of current PPD efforts on infant neurobiological outcomes, highlighting existing research gaps as well as the utility of research in this area to impact long-term health trajectories. Given the established lasting, and potentially intergenerational, negative implications of maternal depression enhanced efforts targeting increased identification and early intervention approaches for PDD that impact health outcomes in both infants and mothers represents a critical public health concern. PMID:26980123

China's coastal wetlands: conservation history, implementation efforts, existing issues and strategies for future improvement.

PubMed

Sun, Zhigao; Sun, Wenguang; Tong, Chuan; Zeng, Congsheng; Yu, Xiang; Mou, Xiaojie

2015-06-01

China has approximately 5.80×10(6)ha coastal wetlands by 2014, accounting for 10.82% of the total area of natural wetlands. Healthy coastal wetland ecosystems play an important role in guaranteeing the territory ecological security and the sustainable development of coastal zone in China. In this paper, the natural geography and the past and present status of China's coastal wetlands were introduced and the five stages (1950s-1970s, 1980s-1991, 1992-2002, 2003-2010 and 2011-present) of China's coastal wetlands conservation from the foundation of the People's Republic in 1949 to present were distinguished and reviewed. Over the past decades, China has made great efforts in coastal wetland conservation, as signified by the implementation of coastal wetland restoration projects, the construction of coastal wetland nature reserves, the practice of routine ecological monitoring and two national wetland surveys, the promulgation of local wetland conservation statutes and specific regulations, the coordination mechanism to enhance management capacity, the wide development of coastal wetland research and public participation, and the extensive communication to strengthen international cooperation. Nonetheless, six major issues recently emerged in China's coastal wetland conservation are evidently existed, including the increasing threats of pollution and human activities, the increasing adverse effects of threaten factors on ecosystem function, the increasing threats of coastal erosion and sea-level rising, the insufficient funding for coastal wetlands conservation, the imperfect legal and management system for coastal wetlands, and the insufficient education, research and international cooperation. Although the threats and pressures on coastal wetlands conservation are still apparent, the future of China's coastal wetlands looks promising since the Chinese government understands that the sustainable development in coastal zone requires new attitudes, sound policies and concerted efforts at all levels. The major strategies for future improvement of China's coastal wetland conservation include: exploring effective measures in response to major threaten factors; improving the conservation and compensation system for coastal wetlands; strengthening coastal wetland legislation and management; increasing funds for coastal wetland conservation and research; and strengthening coastal wetland education and international cooperation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Self-Compassion, Stress, and Coping

PubMed Central

Allen, Ashley Batts; Leary, Mark R.

2010-01-01

People who are high in self-compassion treat themselves with kindness and concern when they experience negative events. The present article examines the construct of self-compassion from the standpoint of research on coping in an effort to understand the ways in which people who are high in self-compassion cope with stressful events. Self-compassionate people tend to rely heavily on positive cognitive restructuring but do not appear to differ from less self-compassionate people in the degree to which they cope through problem-solving and distraction. Existing evidence does not show clear differences in the degree to which people who are low vs. high in self-compassion seek support as a coping strategy, but more research is needed. PMID:20686629

A sustainable approach to controlling oil spills.

PubMed

Al-Majed, Abdul Aziz; Adebayo, Abdulrauf Rasheed; Hossain, M Enamul

2012-12-30

As a result of the huge economic and environmental destruction from oil spills, studies have been directed at improving and deploying natural sorbents which are not only the least expensive but also the safest means of spill control. This research reviews the limitations and environmental impact of existing cleanup methods. It also justifies the need for concerted research effort on oil spill control using natural and sustainable technology concepts. The article proposes future guidelines for the development of a sustainable cleanup technology. Finally, guidelines for the development of a new technology for the Middle East are proposed, which is the use of an abundant resource--date palm fibers--for such techniques. Copyright © 2012 Elsevier Ltd. All rights reserved.

Wind Shear/Turbulence Inputs to Flight Simulation and Systems Certification

NASA Technical Reports Server (NTRS)

Bowles, Roland L. (Editor); Frost, Walter (Editor)

1987-01-01

The purpose of the workshop was to provide a forum for industry, universities, and government to assess current status and likely future requirements for application of flight simulators to aviation safety concerns and system certification issues associated with wind shear and atmospheric turbulence. Research findings presented included characterization of wind shear and turbulence hazards based on modeling efforts and quantitative results obtained from field measurement programs. Future research thrusts needed to maximally exploit flight simulators for aviation safety application involving wind shear and turbulence were identified. The conference contained sessions on: Existing wind shear data and simulator implementation initiatives; Invited papers regarding wind shear and turbulence simulation requirements; and Committee working session reports.

Getting a Bigger Bang for Your Buck: A Collaborative Approach to Enhancing Dementia Education Planning in Long-Term Care Homes

PubMed Central

McAiney, Carrie A.; Hillier, Loretta M.; Ringland, Margaret; Cooper, Nancy

2009-01-01

A collaborative of Ontario-based long-term care associations, researchers, clinicians and educators representing various education initiatives related to dementia care and challenging behaviours used existing research evidence on adult learning principles, knowledge transfer and performance improvement to develop an evidence-based approach to support practice change and improvement in long-term care. The collaborative was led by the two provincial long-term care associations with no external funds to support its activities. This effort illustrates how people with common challenges, visions and goals can work together to share their intellectual and physical resources to address pervasive problems. PMID:21037817

The APRU Global Health Program: Past and Future.

PubMed

Samet, Jonathan; Withers, Mellissa

2016-01-01

The Association of Pacific Rim Universities (APRU) is an international consortium of 45 universities in the Pacific Rim, representing 16 economies, 130 000 faculty members and more than two million students. The APRU Global Health Program aims to expand existing collaborative research efforts among universities to address regional and global health issues. Since its launch in 2007-08, the program has covered a significant range of topics including emerging public health threats, ageing and chronic diseases, infectious diseases and health security issues, among others. The Program's activities in research, training, and service around the globe illustrate the diverse dimensions of global health. In this paper, the major activities to date are outlined and future planned activities are discussed.

Multiprocessor architecture: Synthesis and evaluation

NASA Technical Reports Server (NTRS)

Standley, Hilda M.

1990-01-01

Multiprocessor computed architecture evaluation for structural computations is the focus of the research effort described. Results obtained are expected to lead to more efficient use of existing architectures and to suggest designs for new, application specific, architectures. The brief descriptions given outline a number of related efforts directed toward this purpose. The difficulty is analyzing an existing architecture or in designing a new computer architecture lies in the fact that the performance of a particular architecture, within the context of a given application, is determined by a number of factors. These include, but are not limited to, the efficiency of the computation algorithm, the programming language and support environment, the quality of the program written in the programming language, the multiplicity of the processing elements, the characteristics of the individual processing elements, the interconnection network connecting processors and non-local memories, and the shared memory organization covering the spectrum from no shared memory (all local memory) to one global access memory. These performance determiners may be loosely classified as being software or hardware related. This distinction is not clear or even appropriate in many cases. The effect of the choice of algorithm is ignored by assuming that the algorithm is specified as given. Effort directed toward the removal of the effect of the programming language and program resulted in the design of a high-level parallel programming language. Two characteristics of the fundamental structure of the architecture (memory organization and interconnection network) are examined.

Hypersonic propulsion: Status and challenge

NASA Technical Reports Server (NTRS)

Guy, R. Wayne

1990-01-01

Scientists in the U.S. are again focusing on the challenge of hypersonic flight with the proposed National Aerospace Plane (NASP). This renewed interest has led to an expansion of research related to high speed airbreathing propulsion, in particular, the supersonic combustion ramjet, or scramjet. The history is briefly traced of scramjet research in the U.S., with emphasis on NASA sponsored efforts, from the Hypersonic Research Engine (HRE) to the current status of today's airframe integrated scramjets. The challenges of scramjet technology development from takeover to orbital speeds are outlined. Existing scramjet test facilities such as NASA Langley's Scramjet Test Complex as well as new high Mach number pulse facilities are discussed. The important partnership role of experimental methods and computational fluid dynamics is emphasized for the successful design of single stage to orbit vehicles.

Aerodynamics of advanced axial-flow turbomachinery

NASA Technical Reports Server (NTRS)

Serovy, G. K.; Kavanagh, P.; Kiishi, T. H.

1980-01-01

A multi-task research program on aerodynamic problems in advanced axial-flow turbomachine configurations was carried out at Iowa State University. The elements of this program were intended to contribute directly to the improvement of compressor, fan, and turbine design methods. Experimental efforts in intra-passage flow pattern measurements, unsteady blade row interaction, and control of secondary flow are included, along with computational work on inviscid-viscous interaction blade passage flow techniques. This final report summarizes the results of this program and indicates directions which might be taken in following up these results in future work. In a separate task a study was made of existing turbomachinery research programs and facilities in universities located in the United States. Some potentially significant research topics are discussed which might be successfully attacked in the university atmosphere.

Challenges Evaluating Chemotherapy-Induced Peripheral Neuropathy in Childhood Cancer Survivors.

PubMed

Mohrmann, Caroline; Armer, Jane; Hayashi, Robert J

Children treated for cancer are exposed to a variety of chemotherapeutic agents with known toxicity to the peripheral nervous system. The side effect of peripheral neuropathy can cause changes in sensation, function, and even cause pain. Although peripheral neuropathy is recognized by pediatric oncology nurses as an important and significant side effect, measuring neuropathy can be quite complex for clinical care and research efforts. With more children surviving a cancer diagnosis today, this issue is increasingly important for childhood cancer survivors. This article has reviewed existing literature examining peripheral neuropathy in childhood cancer survivors with particular interest paid to measurement tools available and needs for future research. It is important for nurses to choose appropriate measures for clinical care and research methods in order to have an impact on patients experiencing this condition.

Cryptography and the Internet: lessons and challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCurley, K.S.

1996-12-31

The popularization of the Internet has brought fundamental changes to the world, because it allows a universal method of communication between computers. This carries enormous benefits with it, but also raises many security considerations. Cryptography is a fundamental technology used to provide security of computer networks, and there is currently a widespread engineering effort to incorporate cryptography into various aspects of the Internet. The system-level engineering required to provide security services for the Internet carries some important lessons for researchers whose study is focused on narrowly defined problems. It also offers challenges to the cryptographic research community by raising newmore » questions not adequately addressed by the existing body of knowledge. This paper attempts to summarize some of these lessons and challenges for the cryptographic research community.« less

Sea-floor texture and physiographic zones of the inner continental shelf from Salisbury to Nahant, Massachusetts, including the Merrimack Embayment and Western Massachusetts Bay

USGS Publications Warehouse

Pendleton, Elizabeth E.; Barnhardt, Walter A.; Baldwin, Wayne E.; Foster, David S.; Schwab, William C.; Andrews, Brian D.; Ackerman, Seth D.

2015-10-26

A series of maps that describe the distribution and texture of sea-floor sediments and physiographic zones of Massachusetts State waters from Nahant to Salisbury, Massachusetts, including western Massachusetts Bay, have been produced by using high-resolution geophysical data (interferometric and multibeam swath bathymetry, lidar bathymetry, backscatter intensity, and seismic reflection profiles), sediment samples, and bottom photographs. These interpretations are intended to aid statewide efforts to inventory and manage coastal and marine resources, link with existing data interpretations, and provide information for research focused on coastal evolution and environmental change. Marine geologic mapping of the inner continental shelf of Massachusetts is a statewide cooperative effort of the U.S. Geological Survey and the Massachusetts Office of Coastal Zone Management.

Antiviral strategies to eliminate hepatitis B virus covalently closed circular DNA (cccDNA).

PubMed

Revill, Peter; Locarnini, Stephen

2016-10-01

It has been over 50 years since the discovery of hepatitis B virus (HBV), yet 240 million people worldwide live with chronic HBV, resulting in up to 800000 deaths per year. A cure is yet to be achieved, due largely to a viral nuclear reservoir of transcriptionally active covalently closed circular DNA (cccDNA). While current antiviral therapies are effective at reducing viral replication, they have no impact on the existing cccDNA reservoir. Identifying mechanisms to either eliminate (complete cure) or inactivate (functional cure) HBV cccDNA are a major focus of HBV research worldwide. This review discusses recent advances in efforts to eliminate and/or regulate cccDNA, as well as future directions that may be considered in efforts to cure chronic HBV. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Terminology development towards harmonizing multiple clinical neuroimaging research repositories.

PubMed

Turner, Jessica A; Pasquerello, Danielle; Turner, Matthew D; Keator, David B; Alpert, Kathryn; King, Margaret; Landis, Drew; Calhoun, Vince D; Potkin, Steven G; Tallis, Marcelo; Ambite, Jose Luis; Wang, Lei

2015-07-01

Data sharing and mediation across disparate neuroimaging repositories requires extensive effort to ensure that the different domains of data types are referred to by commonly agreed upon terms. Within the SchizConnect project, which enables querying across decentralized databases of neuroimaging, clinical, and cognitive data from various studies of schizophrenia, we developed a model for each data domain, identified common usable terms that could be agreed upon across the repositories, and linked them to standard ontological terms where possible. We had the goal of facilitating both the current user experience in querying and future automated computations and reasoning regarding the data. We found that existing terminologies are incomplete for these purposes, even with the history of neuroimaging data sharing in the field; and we provide a model for efforts focused on querying multiple clinical neuroimaging repositories.

Terminology development towards harmonizing multiple clinical neuroimaging research repositories

PubMed Central

Turner, Jessica A.; Pasquerello, Danielle; Turner, Matthew D.; Keator, David B.; Alpert, Kathryn; King, Margaret; Landis, Drew; Calhoun, Vince D.; Potkin, Steven G.; Tallis, Marcelo; Ambite, Jose Luis; Wang, Lei

2015-01-01

Data sharing and mediation across disparate neuroimaging repositories requires extensive effort to ensure that the different domains of data types are referred to by commonly agreed upon terms. Within the SchizConnect project, which enables querying across decentralized databases of neuroimaging, clinical, and cognitive data from various studies of schizophrenia, we developed a model for each data domain, identified common usable terms that could be agreed upon across the repositories, and linked them to standard ontological terms where possible. We had the goal of facilitating both the current user experience in querying and future automated computations and reasoning regarding the data. We found that existing terminologies are incomplete for these purposes, even with the history of neuroimaging data sharing in the field; and we provide a model for efforts focused on querying multiple clinical neuroimaging repositories. PMID:26688838

Evaluation of Wiring Constructions for Space Applications

NASA Technical Reports Server (NTRS)

Hammoud, Ahmad N.; Stavnes, Mark W.; Dickman, John E.; Burkhardt, Linda A.; Woodford, Lynn M.; Ide, James R.; Muegge, ED

1994-01-01

A NASA Office of Safety and Mission Assurance (OS&MA) program to develop lightweight, reliable, and safe wiring insulations for aerospace applications is being performed by the NASA Lewis Research Center (LeRC). As part of this effort, a new wiring construction utilizing high strength PTFE (poly tetrafluoroethylene) as the insulation has been tested and compared with the existing military standard polyimide-based MIL-W-81381 wire construction. Electrical properties which were investigated included ac corona inception and extinction voltages (sea level and 60,000 feet), time/current to smoke, and wire fusing time. The two constructions were also characterized in terms of their mechanical properties of flexural strength, abrasion resistance (23 C and 150 C), and dynamic cut-through (23 C and 200 C). The results obtained in this testing effort are presented and discussed in this paper.

Universality of the logarithmic velocity profile restored

NASA Astrophysics Data System (ADS)

Luchini, Paolo

2017-11-01

The logarithmic velocity profile of wall-bounded turbulent flow, despite its widespread adoption in research and in teaching, exhibits discrepancies with both experiments and numerical simulations that have been repeatedly observed in the literature; serious doubts ensued about its precise form and universality, leading to the formulation of alternate theories and hindering ongoing experimental efforts to measure von Kármán's constant. By comparing different geometries of pipe, plane-channel and plane-Couette flow, here we show that such discrepancies can be physically interpreted, and analytically accounted for, through an equally universal higher-order correction caused by the pressure gradient. Inclusion of this term produces a tenfold increase in the adherence of the predicted profile to existing experiments and numerical simulations in all three geometries. Universality of the logarithmic law then emerges beyond doubt and a satisfactorily simple formulation is established. Among the consequences of this formulation is a strongly increased confidence that the Reynolds number of present-day direct numerical simulations is actually high enough to uncover asymptotic behaviour, but research efforts are still needed in order to increase their accuracy.

Engaging a Chemical Disaster Community: Lessons from Graniteville

PubMed Central

Abara, Winston; Wilson, Sacoby; Vena, John; Sanders, Louisiana; Bevington, Tina; Culley, Joan M.; Annang, Lucy; Dalemarre, Laura; Svendsen, Erik

2014-01-01

Community engagement remains a primary objective of public health practice. While this approach has been adopted with success in response to many community health issues, it is rarely adopted in chemical disaster response. Empirical research suggests that management of chemical disasters focuses on the emergency response with almost no community engagement for long-term recovery. Graniteville, an unincorporated and medically underserved community in South Carolina was the site of one of the largest chlorine exposures by a general US population. Following the immediate response, we sought community participation and partnered with community stakeholders and representatives in order to address community-identified health and environmental concerns. Subsequently, we engaged the community through regular town hall meetings, harnessing community capacity, forming coalitions with existing local assets like churches, schools, health centers, and businesses, and hosting community-wide events like health picnics and screenings. Information obtained from these events through discussions, interviews, and surveys facilitated focused public health service which eventually transitioned to community-driven public health research. Specific outcomes of the community engagement efforts and steps taken to ensure sustainability of these efforts and outcomes will be discussed. PMID:24871259

IDEAL: Images Across Domains, Experiments, Algorithms and Learning

NASA Astrophysics Data System (ADS)

Ushizima, Daniela M.; Bale, Hrishikesh A.; Bethel, E. Wes; Ercius, Peter; Helms, Brett A.; Krishnan, Harinarayan; Grinberg, Lea T.; Haranczyk, Maciej; Macdowell, Alastair A.; Odziomek, Katarzyna; Parkinson, Dilworth Y.; Perciano, Talita; Ritchie, Robert O.; Yang, Chao

2016-11-01

Research across science domains is increasingly reliant on image-centric data. Software tools are in high demand to uncover relevant, but hidden, information in digital images, such as those coming from faster next generation high-throughput imaging platforms. The challenge is to analyze the data torrent generated by the advanced instruments efficiently, and provide insights such as measurements for decision-making. In this paper, we overview work performed by an interdisciplinary team of computational and materials scientists, aimed at designing software applications and coordinating research efforts connecting (1) emerging algorithms for dealing with large and complex datasets; (2) data analysis methods with emphasis in pattern recognition and machine learning; and (3) advances in evolving computer architectures. Engineering tools around these efforts accelerate the analyses of image-based recordings, improve reusability and reproducibility, scale scientific procedures by reducing time between experiments, increase efficiency, and open opportunities for more users of the imaging facilities. This paper describes our algorithms and software tools, showing results across image scales, demonstrating how our framework plays a role in improving image understanding for quality control of existent materials and discovery of new compounds.

Databases post-processing in Tensoral

NASA Technical Reports Server (NTRS)

Dresselhaus, Eliot

1994-01-01

The Center for Turbulent Research (CTR) post-processing effort aims to make turbulence simulations and data more readily and usefully available to the research and industrial communities. The Tensoral language, introduced in this document and currently existing in prototype form, is the foundation of this effort. Tensoral provides a convenient and powerful protocol to connect users who wish to analyze fluids databases with the authors who generate them. In this document we introduce Tensoral and its prototype implementation in the form of a user's guide. This guide focuses on use of Tensoral for post-processing turbulence databases. The corresponding document - the Tensoral 'author's guide' - which focuses on how authors can make databases available to users via the Tensoral system - is currently unwritten. Section 1 of this user's guide defines Tensoral's basic notions: we explain the class of problems at hand and how Tensoral abstracts them. Section 2 defines Tensoral syntax for mathematical expressions. Section 3 shows how these expressions make up Tensoral statements. Section 4 shows how Tensoral statements and expressions are embedded into other computer languages (such as C or Vectoral) to make Tensoral programs. We conclude with a complete example program.

The knowledge translation status in selected Eastern-Mediterranean universities and research institutes.

PubMed

Maleki, Katayoun; Hamadeh, Randah R; Gholami, Jaleh; Mandil, Ahmed; Hamid, Saima; Butt, Zahid Ahmad; Bin Saeed, Abdulaziz; El Kheir, Dalia Y M; Saleem, Mohammed; Maqsoud, Sahar; Safi, Najibullah; Abdul-Majeed, Ban A; Majdzadeh, Reza

2014-01-01

A serious worldwide effort to strengthen research based knowledge translation (KT) has begun in recent years and some countries, particularly developed ones, are trying to incorporate KT in their health and health research systems. Keeping in mind the recent economic depression and the need to perform more efficient research, we aimed to assess and compare the KT status of selected health research institutes in the Eastern Mediterranean Regions' countries, and to identify their strengths and weaknesses in the field. After finding the focal points that would steer the focus group discussions (FGDs) and help complete the 'Self Assessment Tool for Research Institutes' (SATORI) tool, each focal point held two FGDs in which researchers, research authorities and other individuals specified in detail further in the study were held. The scores obtained by each institute were evaluated quantitatively, and the transcriptions were analyzed qualitatively with OpenCode software. For ease of analysis the 50 items of the SATORI were classified into 7 main domains: 'priority setting', 'research quality and timeliness', 'researchers' KT capacities', 'facilities and pre-requisites of KT', 'processes and regulations supporting KT', 'interaction with research users', and 'promoting and evaluating the use of knowledge'. Based on the scoring system, the strongest domain was 'research quality and timeliness'. 'Priority setting' was the weakest domain of all. The remaining domains were more or less equal in strength and were not in a favorable state. The qualitative findings confirmed the quantitative findings. The main problem, it seems, is that a KT climate does not exist in the region. And despite the difference in the contexts, there are many similarities in the region's institutes included in this study. Collaborative efforts can play a role in creating this climate by steering countries towards KT and suggesting regional strategic directions according to their needs.

GeosciNET: Building a Global Geoinformatics Partnership

NASA Astrophysics Data System (ADS)

Snyder, W. S.; Lehnert, K. A.; Ito, E.; Harms, U.; Klump, J.

2008-12-01

GeosciNET is a collaboration of several existing geoinformatics efforts organized to provide a more effective data system for geoscience projects. Current members are: CoreWall (www.corewall.org), Geoinformatics for Geochemistry (GfG; www.geoinfogeochem.org), System for Earth Sample Registration (SESAR; www.geosamples.org ), GeoStrat SYS (www.geostratsys.org (formerly: PaleoStrat, www.paleostrat.org)), and the International Continental Drilling Program (ICDP; www.icdp-online.org). GeosciNET's basic goal is to advance coordination, complementarity, and interoperability, and minimize duplication of efforts among the involved partner systems in order to streamline the development and operation of geoinformatics efforts. We believe that by advancing the development and data holdings of its member groups, the overall value of each site will be significantly enhanced and better meet the needs of the users. With the existing membership, GeosciNET can offer a comprehensive, integrated system for data acquisition, dissemination, archiving, visualization, integration, and analysis. The system will enable a single researcher or a group of collaborators to keep track of, visualize, and digitally archive any type of sample- or stratigraphic-based data produced from drill holes, dredges, measured stratigraphic sections, the field, or the laboratory. The challenge is to build a linked system that provides users a library of research data as well as tools to input, discover, access, integrate, manipulate, analyze, and model interdisciplinary data - all without corrupting the original data and insuring that the data are attributed to the originator at all times. Science runs on data, but despite the importance of data (legacy or otherwise), there are currently few convenient mechanisms that enable users to easily input their data into databases. While some efforts such as GfG databases, PetDB and SedDB have worked hard to compile such data, only users' active participation can capture the major part of critical legacy data, and insure that new data enter the digital stream as they are generated. GeosciNET wants to lower the barriers so users can take advantage of geoinformatics resources and embrace its promise as the platform for doing the science of the future. Once these benefits are understood by the user community, the obstacles that currently exist in building a larger geoinformatics system will start to erode. User participation requires the proper tools such as translators that can recognize tags and parse the data accordingly, and incentives such as tools for visualization, synthesis and analysis, and digital collaboration space. A major focus for GeosciNET is to support individual researchers and projects that do not have their own dedicated data management and education and outreach programs. One of the greatest challenges for geoinformatics lies in being perceived as a friendly resource by its users where they can easily link their observations and analyses and integrate them with other data. GeosciNET will be experimenting with mechanisms to accomplish these goals.

Proton-Exchange-Membrane Fuel Cell Powerplants Developed and Tested for Exploration Missions

NASA Technical Reports Server (NTRS)

Hoberecht, Mark A.; Pham, Nang T.

2005-01-01

Proton-exchange-membrane fuel cell (PEMFC) technology has received major attention for terrestrial applications, such as the automotive and residential markets, for the past 20 years. This attention has significantly advanced the maturity of the technology, resulting in ever more compact, efficient, reliable, and inexpensive PEMFC designs. In comparison to the terrestrial operating environment, the space operating environment is much more demanding. Microgravity to high-gravity loads and the need to use pure oxygen (rather than air) as the fuel cell oxidizer place more stringent demands on PEMFC technology. NASA and its partners from industry are leveraging terrestrial PEMFC advancements by conducting parallel space technology development for future exploration missions. A team from the NASA Glenn Research Center, NASA Johnson Space Center, and NASA Kennedy Space Center recently completed the first phase of a PEMFC powerplant development effort for exploration missions. The industry partners for this phase of the development effort were ElectroChem, Inc., and Teledyne Energy Systems, Inc. Under contract to Glenn, both of these industry partners successfully designed, fabricated, and tested a breadboard PEMFC powerplant in the 1- to 5-kW power range. These powerplants were based on existing company-proprietary fuel cell stack designs, combined with off-the-shelf components, which formed the balance of the powerplant design. Subsequent to the contractor development efforts, both powerplants were independently tested at Johnson to verify operational and performance characteristics, and to determine suitability for further technology development in the second phase of the NASA-led effort. Following the independent NASA testing, Teledyne Energy Systems, Inc., was selected to develop an engineering model PEMFC powerplant. This effort was initiated by the 2nd Generation Reusable Launch Vehicle (RLV) Program Office in 2001; it transitioned to the Next Generation Launch Technologies (NGLT) Program Office in 2003. The effort is now being funded by the Exploration Program Office. We plan to summarize the results from the ongoing engineering model PEMFC powerplant development in a future Research & Technology article.

Proton-Exchange-Membrane Fuel Cell Powerplants Developed and Tested for Exploration Missions

NASA Astrophysics Data System (ADS)

Hoberecht, Mark A.; Pham, Nang T.

2005-06-01

Proton-exchange-membrane fuel cell (PEMFC) technology has received major attention for terrestrial applications, such as the automotive and residential markets, for the past 20 years. This attention has significantly advanced the maturity of the technology, resulting in ever more compact, efficient, reliable, and inexpensive PEMFC designs. In comparison to the terrestrial operating environment, the space operating environment is much more demanding. Microgravity to high-gravity loads and the need to use pure oxygen (rather than air) as the fuel cell oxidizer place more stringent demands on PEMFC technology. NASA and its partners from industry are leveraging terrestrial PEMFC advancements by conducting parallel space technology development for future exploration missions. A team from the NASA Glenn Research Center, NASA Johnson Space Center, and NASA Kennedy Space Center recently completed the first phase of a PEMFC powerplant development effort for exploration missions. The industry partners for this phase of the development effort were ElectroChem, Inc., and Teledyne Energy Systems, Inc. Under contract to Glenn, both of these industry partners successfully designed, fabricated, and tested a breadboard PEMFC powerplant in the 1- to 5-kW power range. These powerplants were based on existing company-proprietary fuel cell stack designs, combined with off-the-shelf components, which formed the balance of the powerplant design. Subsequent to the contractor development efforts, both powerplants were independently tested at Johnson to verify operational and performance characteristics, and to determine suitability for further technology development in the second phase of the NASA-led effort. Following the independent NASA testing, Teledyne Energy Systems, Inc., was selected to develop an engineering model PEMFC powerplant. This effort was initiated by the 2nd Generation Reusable Launch Vehicle (RLV) Program Office in 2001; it transitioned to the Next Generation Launch Technologies (NGLT) Program Office in 2003. The effort is now being funded by the Exploration Program Office. We plan to summarize the results from the ongoing engineering model PEMFC powerplant development in a future Research & Technology article.

Stigma and intellectual disability: potential application of mental illness research.

PubMed

Ditchman, Nicole; Werner, Shirli; Kosyluk, Kristin; Jones, Nev; Elg, Brianna; Corrigan, Patrick W

2013-05-01

Individuals with intellectual disabilities (ID) and individuals with mental illness are consistently found to be among the most socially excluded populations and continue to face substantial health, housing, and employment disparities due to stigma. Although this has spurred extensive research efforts and theoretical advancements in the study of stigma toward mental illness, the stigma of ID has received only limited attention. In this article we explore the application of mental illness stigma research for ID. We carefully reviewed the existing research on mental illness stigma as a foundation for a parallel summary of the empirical literature on attitudes and stigma related to ID. Based on our review, there has not been a systematic approach to the study of stigma toward ID. However, multilevel conceptual models of stigma have received much attention in the mental illness literature. These models have been used to inform targeted interventions and have application to the study of the stigma process for individuals with ID. Nonetheless, there are indeed key differences between-as well as substantial variability within-the ID and mental illness populations that must be considered. Stigma is an issue of social justice impacting the lives of individuals with ID, yet there remains virtually no systematic framework applied to the understanding of the stigma process for this group. Future research can draw on the stigma models developed in the mental illness literature to guide more rigorous research efforts and ultimately the development of effective, multilevel stigma-change strategies for ID.

The use of biospecimens in population-based research: a review of the National Cancer Institute's Division of Cancer Control and Population Sciences grant portfolio.

PubMed

Carrick, Danielle M; Mette, Eliza; Hoyle, Brittany; Rogers, Scott D; Gillanders, Elizabeth M; Schully, Sheri D; Mechanic, Leah E

2014-08-01

Over the past two decades, researchers have increasingly used human biospecimens to evaluate hypotheses related to disease risk, outcomes and treatment. We conducted an analysis of population-science cancer research grants funded by the National Cancer Institute (NCI) to gain a more comprehensive understanding of biospecimens and common derivatives involved in those studies and identify opportunities for advancing the field. Data available for 1,018 extramural, peer-reviewed grants (active as of July 2012) supported by the Division of Cancer Control and Population Sciences (DCCPS), the NCI Division that supports cancer control and population-science extramural research grants, were analyzed. 455 of the grants were determined to involve biospecimens or derivatives. The most common specimen types included were whole blood (51% of grants), serum or plasma (40%), tissue (39%), and the biospecimen derivative, DNA (66%). While use of biospecimens in molecular epidemiology has become common, biospecimens for behavioral and social research is emerging, as observed in our analysis. Additionally, we found the majority of grants were using already existing biospecimens (63%). Grants that involved use of existing biospecimens resulted in lower costs (studies that used existing serum/plasma biospecimens were 4.2 times less expensive) and more publications per year (1.4 times) than grants collecting new biospecimens. This analysis serves as a first step at understanding the types of biospecimen collections supported by NCI DCCPS. There is room to encourage increased use of archived biospecimens and new collections of rarer specimen and cancer types, as well as for behavioral and social research. To facilitate these efforts, we are working to better catalogue our funded resources and make that data available to the extramural community.

The Incident Command System: a literature review.

PubMed

Jensen, Jessica; Thompson, Steven

2016-01-01

Given the foundational and the fundamental role that the Incident Command System (ICS) is intended to play in on-scene response efforts across the United States, it is important to determine what is known about the system and how this is known. Accordingly, this study addresses the following research question: 'How has research explored the ICS?'. To probe this question, a methodological review of the scant, but widening, pool of research literature directly related to the ICS was conducted. This paper reports on the findings of the analysis related to the focus, theoretical frameworks, population and sampling, methods, results, and conclusions of the existing research literature. While undertaken using different methodological approaches, the ICS research suggests that the system may be limited in its usefulness. In addition, the paper discusses the implications of the research for the state of knowledge of the system and for the direction of future research. © 2016 The Author(s). Disasters © Overseas Development Institute, 2016.

Community-Wide Education Outreach for the Ridge2000 Research Program

NASA Astrophysics Data System (ADS)

Goehring, E.

2004-12-01

Ridge2000 is a multidisciplinary NSF sponsored research initiative to explore Earth's spreading ridge system as an integrated whole. The Ridge2000 community is comprised of scientists from universities and research institutions across the country. Building on existing exemplary outreach efforts (e.g., REVEL, Dive&Discover, Volcanoes of the Deep Sea IMAX), Ridge2000 education outreach has begun to develop community-wide education offerings - programs to which Ridge2000 scientists and others may contribute. Community-wide efforts offer the advantages of serving larger audiences of scientists as well as educators and students and providing avenues for scientists interested in education outreach but with limited time or experience. Coordination of researchers' educational efforts also better leverages the resources of the funding agency - NSF. Here we discuss an exciting Ridge2000 pilot program called SEAS - Student Experiments At Sea. SEAS is a web-based program for middle and high school students to learn science by doing science. SEAS students study the exciting, relatively unexplored world of hydrothermal vents and learn to ask questions about this environment just as researchers do. SEAS goes beyond "follow-along" outreach by inviting students to participate in research through formal proposal and report competitions. The program was concept-tested during the 2003-2004 academic year, with 14 pilot teachers and approximately 800 students. Five student experiments were conducted at sea, with data posted to the website during the cruise. Student reports as well as scientist comments are posted there as well (http://www.ridge2000.org/SEAS/). It was an exciting year! Over 20 Ridge2000 scientists contributed their time and expertise to the SEAS program in its first year. Scientists are invited to contribute in a variety of ways, all of which help satisfy the requirement's of NSF's Broader Impacts Criterion. They may help develop curriculum topics, consult on experimental design, review student proposals and final reports, and/or host student experiments during a research cruise. Many contributions require less than a day's effort. By sharing the load, no one scientist is burdened, nor expected to contribute additional funding. Even better, the Ridge2000 office assumes responsibility for the program development, funding, evaluation and dissemination. When we work together, the possibilities are endless.

Early career professional development issues for military academic psychiatrists.

PubMed

Warner, Christopher H; Bobo, William V; Flynn, Julianne

2005-01-01

Academically motivated graduates of military psychiatric residency programs confront serious challenges. In this article, the authors present a junior faculty development model organized around four overlapping domains: mentorship, scholarship, research, and career planning/development. Using these four domains as a platform for discussion, the authors focus on challenges facing academically oriented early-career military psychiatrists and provide guidance. The authors believe that a proactive stance, skillful mentoring, self-awareness through conscious planning and effort, ability to capitalize on existing opportunities for growth, and attention to detail are all vital to the junior military psychiatrist.

Women in physics in the United States: Recruitment and retention

NASA Astrophysics Data System (ADS)

Abramzon, Nina; Benson, Patrice; Bertschinger, Edmund; Blessing, Susan; Cochran, Geraldine L.; Cox, Anne; Cunningham, Beth; Galbraith-Frew, Jessica; Johnson, Jolene; Kerby, Leslie; Lalanne, Elaine; O'Donnell, Christine; Petty, Sara; Sampath, Sujatha; Seestrom, Susan; Singh, Chandralekha; Spencer, Cherrill; Woodle, Kathryne Sparks; Yennello, Sherry

2015-12-01

Initiatives to increase the number, persistence, and success of women in physics in the United States reach preteen girls through senior women. Programs exist at both the local and national levels. In addition, researchers have investigated issues related to gender equity in physics and physics education. Anecdotal evidence suggests increased media coverage of the underrepresentation of women in science. All of these efforts are motivated and made more effective by the continued collection and presentation of data on the presence, persistence, and promise of women in physics.

Partners in Technology

NASA Technical Reports Server (NTRS)

1984-01-01

Deere and Company scientists are working with various NASA centers in a multifaceted technical exchange program investigating areas of aerospace technology that can be applied to company's products. This is a non-traditional type spinoff in that it does not simply reapply existing technology but development of new technology using Deere's extensive R & D capability to complement NASA's efforts, adapting NASA information to new research paths and providing feedback of importance to NASA's own work. NASA/Deere exchange extends to these areas: Composite materials, ceramics, wear and lubrication, plasma coatings and sensors, and electronics.

Strategies for sustaining effective conservation partnerships

USGS Publications Warehouse

Alden, H.R.; Schroeder, R.L.

1998-01-01

Resource management partnerships among a wide variety of agencies and private groups are increasing in number across the country. The Colorado Rockies Regional Cooperative represents an early example of a grassroots effort of 14 partners to cooperate in the areas of research, education, and resource management. The cooperative conducted a survey of existing resource management partners and partnerships to determine what is necessary to establish and sustain effective partnerships. Survey findings, recent literature, and the experience of the Colorado Rockies Regional Cooperative suggest specific strategies for sustaining effective resource management partnerships.

Microarrays in brain research: the good, the bad and the ugly.

PubMed

Mirnics, K

2001-06-01

Making sense of microarray data is a complex process, in which the interpretation of findings will depend on the overall experimental design and judgement of the investigator performing the analysis. As a result, differences in tissue harvesting, microarray types, sample labelling and data analysis procedures make post hoc sharing of microarray data a great challenge. To ensure rapid and meaningful data exchange, we need to create some order out of the existing chaos. In these ground-breaking microarray standardization and data sharing efforts, NIH agencies should take a leading role

Using artificial intelligence to control fluid flow computations

NASA Technical Reports Server (NTRS)

Gelsey, Andrew

1992-01-01

Computational simulation is an essential tool for the prediction of fluid flow. Many powerful simulation programs exist today. However, using these programs to reliably analyze fluid flow and other physical situations requires considerable human effort and expertise to set up a simulation, determine whether the output makes sense, and repeatedly run the simulation with different inputs until a satisfactory result is achieved. Automating this process is not only of considerable practical importance but will also significantly advance basic artificial intelligence (AI) research in reasoning about the physical world.

WikiPEATia - a web based platform for assembling peatland data through ‘crowd sourcing’

NASA Astrophysics Data System (ADS)

Wisser, D.; Glidden, S.; Fieseher, C.; Treat, C. C.; Routhier, M.; Frolking, S. E.

2009-12-01

The Earth System Science community is realizing that peatlands are an important and unique terrestrial ecosystem that has not yet been well-integrated into large-scale earth system analyses. A major hurdle is the lack of accessible, geospatial data of peatland distribution, coupled with data on peatland properties (e.g., vegetation composition, peat depth, basal dates, soil chemistry, peatland class) at the global scale. This data, however, is available at the local scale. Although a comprehensive global database on peatlands probably lags similar data on more economically important ecosystems such as forests, grasslands, croplands, a large amount of field data have been collected over the past several decades. A few efforts have been made to map peatlands at large scales but existing data have not been assembled into a single geospatial database that is publicly accessible or do not depict data with a level of detail that is needed in the Earth System Science Community. A global peatland database would contribute to advances in a number of research fields such as hydrology, vegetation and ecosystem modeling, permafrost modeling, and earth system modeling. We present a Web 2.0 approach that uses state-of-the-art webserver and innovative online mapping technologies and is designed to create such a global database through ‘crowd-sourcing’. Primary functions of the online system include form-driven textual user input of peatland research metadata, spatial data input of peatland areas via a mapping interface, database editing and querying editing capabilities, as well as advanced visualization and data analysis tools. WikiPEATia provides an integrated information technology platform for assembling, integrating, and posting peatland-related geospatial datasets facilitates and encourages research community involvement. A successful effort will make existing peatland data much more useful to the research community, and will help to identify significant data gaps.

MIDWESTERN REGIONAL CENTER OF THE DOE NATIONAL INSTITUTE FOR CLIMATIC CHANGE RESEARCH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burton, Andrew J.

2014-02-28

The goal of NICCR (National Institute for Climatic Change Research) was to mobilize university researchers, from all regions of the country, in support of the climatic change research objectives of DOE/BER. The NICCR Midwestern Regional Center (MRC) supported work in the following states: North Dakota, South Dakota, Nebraska, Kansas, Oklahoma, Minnesota, Iowa, Missouri, Wisconsin, Illinois, Michigan, Indiana, and Ohio. The MRC of NICCR was able to support nearly $8 million in climatic change research, including $6,671,303 for twenty projects solicited and selected by the MRC over five requests for proposals (RFPs) and $1,051,666 for the final year of ten projectsmore » from the discontinued DOE NIGEC (National Institute for Global Environmental Change) program. The projects selected and funded by the MRC resulted in 135 peer-reviewed publications and supported the training of 25 PhD students and 23 Masters students. Another 36 publications were generated by the final year of continuing NIGEC projects supported by the MRC. The projects funded by the MRC used a variety of approaches to answer questions relevant to the DOE’s climate change research program. These included experiments that manipulated temperature, moisture and other global change factors; studies that sought to understand how the distribution of species and ecosystems might change under future climates; studies that used measurements and modeling to examine current ecosystem fluxes of energy and mass and those that would exist under future conditions; and studies that synthesized existing data sets to improve our understanding of the effects of climatic change on terrestrial ecosystems. In all of these efforts, the MRC specifically sought to identify and quantify responses of terrestrial ecosystems that were not well understood or not well modeled by current efforts. The MRC also sought to better understand and model important feedbacks between terrestrial ecosystems, atmospheric chemistry, and regional and global climate systems. The broad variety of projects the MRC has supported gave us a unique opportunity to greatly improve our ability to predict the future health, composition and function of important agricultural and natural terrestrial ecosystems within the Midwestern Region.« less

Challenges in adapting existing clinical natural language processing systems to multiple, diverse health care settings.

PubMed

Carrell, David S; Schoen, Robert E; Leffler, Daniel A; Morris, Michele; Rose, Sherri; Baer, Andrew; Crockett, Seth D; Gourevitch, Rebecca A; Dean, Katie M; Mehrotra, Ateev

2017-09-01

Widespread application of clinical natural language processing (NLP) systems requires taking existing NLP systems and adapting them to diverse and heterogeneous settings. We describe the challenges faced and lessons learned in adapting an existing NLP system for measuring colonoscopy quality. Colonoscopy and pathology reports from 4 settings during 2013-2015, varying by geographic location, practice type, compensation structure, and electronic health record. Though successful, adaptation required considerably more time and effort than anticipated. Typical NLP challenges in assembling corpora, diverse report structures, and idiosyncratic linguistic content were greatly magnified. Strategies for addressing adaptation challenges include assessing site-specific diversity, setting realistic timelines, leveraging local electronic health record expertise, and undertaking extensive iterative development. More research is needed on how to make it easier to adapt NLP systems to new clinical settings. A key challenge in widespread application of NLP is adapting existing systems to new clinical settings. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Toward a Visualization-Supported Workflow for Cyber Alert Management using Threat Models and Human-Centered Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Franklin, Lyndsey; Pirrung, Megan A.; Blaha, Leslie M.

Cyber network analysts follow complex processes in their investigations of potential threats to their network. Much research is dedicated to providing automated tool support in the effort to make their tasks more efficient, accurate, and timely. This tool support comes in a variety of implementations from machine learning algorithms that monitor streams of data to visual analytic environments for exploring rich and noisy data sets. Cyber analysts, however, often speak of a need for tools which help them merge the data they already have and help them establish appropriate baselines against which to compare potential anomalies. Furthermore, existing threat modelsmore » that cyber analysts regularly use to structure their investigation are not often leveraged in support tools. We report on our work with cyber analysts to understand they analytic process and how one such model, the MITRE ATT&CK Matrix [32], is used to structure their analytic thinking. We present our efforts to map specific data needed by analysts into the threat model to inform our eventual visualization designs. We examine data mapping for gaps where the threat model is under-supported by either data or tools. We discuss these gaps as potential design spaces for future research efforts. We also discuss the design of a prototype tool that combines machine-learning and visualization components to support cyber analysts working with this threat model.« less

Identifying obstacles and ranking common biological control research priorities for Europe to manage most economically important pests in arable, vegetable and perennial crops.

PubMed

Lamichhane, Jay Ram; Bischoff-Schaefer, Monika; Bluemel, Sylvia; Dachbrodt-Saaydeh, Silke; Dreux, Laure; Jansen, Jean-Pierre; Kiss, Jozsef; Köhl, Jürgen; Kudsk, Per; Malausa, Thibaut; Messéan, Antoine; Nicot, Philippe C; Ricci, Pierre; Thibierge, Jérôme; Villeneuve, François

2017-01-01

EU agriculture is currently in transition from conventional crop protection to integrated pest management (IPM). Because biocontrol is a key component of IPM, many European countries recently have intensified their national efforts on biocontrol research and innovation (R&I), although such initiatives are often fragmented. The operational outputs of national efforts would benefit from closer collaboration among stakeholders via transnationally coordinated approaches, as most economically important pests are similar across Europe. This paper proposes a common European framework on biocontrol R&I. It identifies generic R&I bottlenecks and needs as well as priorities for three crop types (arable, vegetable and perennial crops). The existing gap between the market offers of biocontrol solutions and the demand of growers, the lengthy and expensive registration process for biocontrol solutions and their varying effectiveness due to variable climatic conditions and site-specific factors across Europe are key obstacles hindering the development and adoption of biocontrol solutions in Europe. Considering arable, vegetable and perennial crops, a dozen common target pests are identified for each type of crop and ranked by order of importance at European level. Such a ranked list indicates numerous topics on which future joint transnational efforts would be justified. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Assessing the effects of fire disturbances on ecosystems: A scientific agenda for research and management

USGS Publications Warehouse

Schmoldt, D.L.; Peterson, D.L.; Keane, R.E.; Lenihan, J.M.; McKenzie, D.; Weise, D.R.; Sandberg, D.V.

1999-01-01

A team of fire scientists and resource managers convened 17-19 April 1996 in Seattle, Washington, to assess the effects of fire disturbance on ecosystems. Objectives of this workshop were to develop scientific recommendations for future fire research and management activities. These recommendations included a series of numerically ranked scientific and managerial questions and responses focusing on (1) links among fire effects, fuels, and climate; (2) fire as a large-scale disturbance; (3) fire-effects modeling structures; and (4) managerial concerns, applications, and decision support. At the present time, understanding of fire effects and the ability to extrapolate fire-effects knowledge to large spatial scales are limited, because most data have been collected at small spatial scales for specific applications. Although we clearly need more large-scale fire-effects data, it will be more expedient to concentrate efforts on improving and linking existing models that simulate fire effects in a georeferenced format while integrating empirical data as they become available. A significant component of this effort should be improved communication between modelers and managers to develop modeling tools to use in a planning context. Another component of this modeling effort should improve our ability to predict the interactions of fire and potential climatic change at very large spatial scales. The priority issues and approaches described here provide a template for fire science and fire management programs in the next decade and beyond.

Exploring risk communication - results of a research project focussed on effectiveness evaluation

NASA Astrophysics Data System (ADS)

Charrière, Marie; Bogaard, Thom; Junier, Sandra; Mostert, Erik

2016-04-01

The need for effective science communication and outreach efforts is widely acknowledged in the academic community. In the field of Disaster Risk Reduction, the importance of communication is clearly stressed, e.g. in the newly adopted Sendai Framework for Disaster Risk Reduction 2015-2030 (under the 1st priority of action: understanding disaster risk). Consequently, we see increasing risk communication activities. However, the effectiveness of these activities is rarely evaluated. To address this gap, several research activities were conducted in the context of the Marie Curie Initial Training Network "Changes", the results of which we will present and discuss. First, results of a literature review show, among others, that research on effectiveness is mainly focussed on the assessment of users' needs and their ability to understand the content, rather than on the final impact of the risk communication efforts. Moreover, lab-environment research is more often undertaken than assessment of real communication efforts. Second, a comparison between perceptions of risk managers and the general public of risk communication in a French Alps Valley highlighted a gap between the two groups in terms of amount of information needed (who wants more), the important topics to address (what) and the media to use (how). Third, interviews with developers of smartphone applications for disseminating avalanche risk information showed a variety of current practices and the absence of measurements of real their effectiveness. However, our analysis allowed identifying good practices that can be an inspiration for risk communication related to other hazards. Fourth, an exhibition has been set up following a collaborative approached based on stakeholder engagement. Using a pre/post-test design, the immediate impact of the exhibition, which aimed at increasing the risk awareness of the population (Ubaye Valley, France), was measured. The data obtained suggests that visiting the exhibition increased risk awareness. It appeared that general indicators to measure change in risk awareness, such as perceived awareness or vulnerability, are more powerful than specific ones, such as perceived consequences of a given natural hazard event. Moreover, although the collaborative process was not formally assessed, we observed that the development of the exhibition promoted relationships between stakeholders, the engagement of local stakeholders in science, the exchange between generations, and further communication efforts. This broad collection of research activities applied addressed different viewpoints on the topic of the effectiveness of risk communication related to natural hazards. The evaluation of existing practices allowed identifying current limitations of risk communication and helped develop a research design that enables testing the effectiveness of a real communication effort. Based on this research, recommendations for risk communication applications and further evaluation research can be made.

Assessing country-level efforts to link research to action.

PubMed Central

Lavis, John N.; Lomas, Jonathan; Hamid, Maimunah; Sewankambo, Nelson K.

2006-01-01

We developed a framework for assessing country-level efforts to link research to action. The framework has four elements. The first element assesses the general climate (how those who fund research, universities, researchers and users of research support or place value on efforts to link research to action). The second element addresses the production of research (how priority setting ensures that users' needs are identified and how scoping reviews, systematic reviews and single studies are undertaken to address these needs). The third element addresses the mix of four clusters of activities used to link research to action. These include push efforts (how strategies are used to support action based on the messages arising from research), efforts to facilitate "user pull" (how "one-stop shopping" is provided for optimally packaged high-quality reviews either alone or as part of a national electronic library for health, how these reviews are profiled during "teachable moments" such as intense media coverage, and how rapid-response units meet users' needs for the best research), "user pull" efforts undertaken by those who use research (how users assess their capacity to use research and how structures and processes are changed to support the use of research) and exchange efforts (how meaningful partnerships between researchers and users help them to jointly ask and answer relevant questions). The fourth element addresses approaches to evaluation (how support is provided for rigorous evaluations of efforts to link research to action). PMID:16917649

Building Format-Agnostic Metadata Repositories

NASA Astrophysics Data System (ADS)

Cechini, M.; Pilone, D.

2010-12-01

This presentation will discuss the problems that surround persisting and discovering metadata in multiple formats; a set of tenets that must be addressed in a solution; and NASA’s Earth Observing System (EOS) ClearingHOuse’s (ECHO) proposed approach. In order to facilitate cross-discipline data analysis, Earth Scientists will potentially interact with more than one data source. The most common data discovery paradigm relies on services and/or applications facilitating the discovery and presentation of metadata. What may not be common are the formats in which the metadata are formatted. As the number of sources and datasets utilized for research increases, it becomes more likely that a researcher will encounter conflicting metadata formats. Metadata repositories, such as the EOS ClearingHOuse (ECHO), along with data centers, must identify ways to address this issue. In order to define the solution to this problem, the following tenets are identified: - There exists a set of ‘core’ metadata fields recommended for data discovery. - There exists a set of users who will require the entire metadata record for advanced analysis. - There exists a set of users who will require a ‘core’ set of metadata fields for discovery only. - There will never be a cessation of new formats or a total retirement of all old formats. - Users should be presented metadata in a consistent format. ECHO has undertaken an effort to transform its metadata ingest and discovery services in order to support the growing set of metadata formats. In order to address the previously listed items, ECHO’s new metadata processing paradigm utilizes the following approach: - Identify a cross-format set of ‘core’ metadata fields necessary for discovery. - Implement format-specific indexers to extract the ‘core’ metadata fields into an optimized query capability. - Archive the original metadata in its entirety for presentation to users requiring the full record. - Provide on-demand translation of ‘core’ metadata to any supported result format. With this identified approach, the Earth Scientist is provided with a consistent data representation as they interact with a variety of datasets that utilize multiple metadata formats. They are then able to focus their efforts on the more critical research activities which they are undertaking.

A BRIDGE partnership model for health management education in the Slovak Republic.

PubMed

West, D J; Krcmery, V; Rusnakova, V; Murgas, M

1998-01-01

An innovative Health Management Education Partnership (HMEP) was initiated to develop management education initiatives through the exchange of information and ideas. Health education efforts, projects and activities exist between the University of Scranton and three strategic partners in the Slovak Republic: Trnava University, the Health Management School and the University of Matej Bel. The BRIDGE model (Building Relationships in Developing and Growing Economies) utilizes several innovative educational initiatives and strategic projects including a professional journal, faculty development, professional development, curriculum development, certification and accreditation, faculty-students exchange and development of educational materials and modules. The BRIDGE organizational structure is reviewed as well as specific workplan objectives to operationalize the HMEP encouraging mutual cooperation, collaboration and sustainability of efforts. The model stresses implementation, monitoring, and evaluation of all initiatives through a strong community effort, focus on research, deployment of educational resources, curriculum modification, development of interpartnership activities, conferences, workshops, fieldwork experiences and study tours. Applied management practices enhance market-oriented solutions to health care delivery problems emphasizing a focus on privatization and entrepreneurship through education.

How can the struggling research community adapt to the information age?

NASA Astrophysics Data System (ADS)

Bouma, Johan

2017-04-01

The widespread use of internet and social media has fundamentally changed the relationship of research with society culminating in :"fact-free politics". Rather than operate from the position of distant experts who are graciously willing to serve mankind, expecting gratitude and admiration in return, scientists encounter knowledgeable stakeholders realizing :"citizen science". Some see science as just producing :"yet another opinion". It is time now to re-establish and advocate the basic power of the scientific effort, involving stakeholders systematically, by: analysing a problem, shaping it into a researchable item, applying scientifically sound data and methods, testing results statistically and presenting results, realizing that "the" truth does not exist. The seventeen UN Sustainable Development Goals (SDG's) provide an attractive focus for inter- and transdisciplinary research approaches defining a series of options covering several SDG's in a system's analysis. Involved stakeholders and policy makers remain responsible to select their favorite option.

Entrepreneurship by any other name: self-sufficiency versus innovation.

PubMed

Parker Harris, Sarah; Caldwell, Kate; Renko, Maija

2014-01-01

Entrepreneurship has been promoted as an innovative strategy to address the employment of people with disabilities. Research has predominantly focused on the self-sufficiency aspect without fully integrating entrepreneurship literature in the areas of theory, systems change, and demonstration projects. Subsequently there are gaps in services, policies, and research in this field that, in turn, have limited our understanding of the support needs and barriers or facilitators of entrepreneurs with disabilities. A thorough analysis of the literature in these areas led to the development of two core concepts that need to be addressed in integrating entrepreneurship into disability employment research and policy: clarity in operational definitions and better disability statistics and outcome measures. This article interrogates existing research and policy efforts in this regard to argue for a necessary shift in the field from focusing on entrepreneurship as self-sufficiency to understanding entrepreneurship as innovation.

Nursing and health sciences workforce diversity research using PhotoVoice: a college and high school student participatory project.

PubMed

Benavides-Vaello, Sandra; Katz, Janet R; Peterson, Jeffery Chaichana; Allen, Carol B; Paul, Robbie; Charette-Bluff, Andrea Lelana; Morris, Phyllis

2014-04-01

This participatory study used PhotoVoice and qualitative description to (a) mentor baccalaureate nursing and college students in workforce diversity research; (b) explore barriers and facilitators encountered by rural American Indian, Hispanic, and other high school students when attending college and pursuing careers in nursing or the health sciences; and (c) model a process of social action to help existing and future students. Baccalaureate nursing and graduate students participated in all stages of research, including dissemination. Five themes emerged from analysis of PhotoVoice data: (a) being afraid; (b) believing; (c) taking small steps; (d) facing fears; and (e) using support systems. Findings underscore the importance of helping students participate in efforts to increase work-force diversity through research. Increasing nursing and health sciences workforce diversity may require strategies developed within and tailored to specific cultures and communities. Copyright 2014, SLACK Incorporated.

Surgical robotics for patient safety in the perioperative environment: realizing the promise.

PubMed

Fuji Lai; Louw, Deon

2007-06-01

Surgery is at a crossroads of complexity. However, there is a potential path toward patient safety. One such course is to leverage computer and robotic assist techniques in the reduction and interception of error in the perioperative environment. This white paper attempts to facilitate the road toward realizing that promise by outlining a research agenda. The paper will briefly review the current status of surgical robotics and summarize any conclusions that can be reached to date based on existing research. It will then lay out a roadmap for future research to determine how surgical robots should be optimally designed and integrated into the perioperative workflow and process. Successful movement down this path would involve focused efforts and multiagency collaboration to address the research priorities outlined, thereby realizing the full potential of surgical robotics to augment human capabilities, enhance task performance, extend the reach of surgical care, improve health care quality, and ultimately enhance patient safety.