Effects of protease-activated receptor 1 inhibition on anxiety and fear following status epilepticus.

PubMed

Bogovyk, Ruslan; Lunko, Oleksii; Fedoriuk, Mihail; Isaev, Dmytro; Krishtal, Oleg; Holmes, Gregory L; Isaeva, Elena

2017-02-01

Protease-activated receptor 1 (PAR1) is an important contributor to the pathogenesis of a variety of brain disorders associated with a risk of epilepsy development. Using the lithium-pilocarpine model of temporal lobe epilepsy (TLE), we recently showed that inhibition of this receptor during the first ten days after pilocarpine-induced status epilepticus (SE) results in substantial anti-epileptogenic and neuroprotective effects. As PAR1 is expressed in the central nervous system regions of importance for processing emotional reactions, including amygdala and hippocampus, and TLE is frequently associated with a chronic alteration of the functions of these regions, we tested the hypothesis that PAR1 inhibition could modulate emotionally driven behavioral responses of rats experiencing SE. We showed that SE induces a chronic decrease in the animals' anxiety-related behavior and an increase of locomotor activity. PAR1 inhibition after SE abolished the alteration of the anxiety level but does not affect the increase of locomotor activity in the open field and elevated plus maze tests. Moreover, while PAR1 inhibition produces an impairment of memory recall in the context fear conditioning paradigm in the control group, it substantially improves contextual and cued fear learning in rats experiencing SE. These data suggest that PAR1-dependent signaling is involved in the mechanisms underlying emotional disorders in epilepsy. Copyright © 2016 Elsevier Inc. All rights reserved.

Bank ownership, lending, and local economic performance during the 2008–2009 financial crisis

PubMed Central

Coleman, Nicholas; Feler, Leo

2017-01-01

Although government banks are frequently associated with political capture and resource misallocation, they may be well-positioned during times of crisis to provide countercyclical support. Following the collapse of Lehman Brothers in September 2008, Brazil’s government banks substantially increased lending. Localities in Brazil with a high share of government banks received more loans and experienced better employment outcomes relative to localities with a low share of government banks. While increased government bank lending mitigated an economic downturn, we find that this lending was politically targeted, inefficiently allocated, and reduced productivity growth. PMID:28936027

Bank ownership, lending, and local economic performance during the 2008-2009 financial crisis.

PubMed

Coleman, Nicholas; Feler, Leo

2015-04-01

Although government banks are frequently associated with political capture and resource misallocation, they may be well-positioned during times of crisis to provide countercyclical support. Following the collapse of Lehman Brothers in September 2008, Brazil's government banks substantially increased lending. Localities in Brazil with a high share of government banks received more loans and experienced better employment outcomes relative to localities with a low share of government banks. While increased government bank lending mitigated an economic downturn, we find that this lending was politically targeted, inefficiently allocated, and reduced productivity growth.

Future treatment and research directions in distal radius fracture.

PubMed

Jupiter, Jesse

2012-05-01

Whether or not they will have their lives dramatically extended in the next few decades, it is clear that people are living longer, healthier, and more active lives. The two peak incidences of distal radius fractures will remain within the pediatric and geriatric age groups, with the latter experiencing a substantial increase in the coming years. This article attempts to project future developments with regard to epidemiology, risk and prevention, fracture assessment, and treatment of distal radius fractures, and the ever increasing concern for the economic impact of this prevalent injury. Copyright © 2012. Published by Elsevier Inc.

Obsessive Compulsive Disorder Treatment in Patients with Down Syndrome: A Case Series

ERIC Educational Resources Information Center

Sutor, Bruce; Hansen, Mark R.; Black, John L.

2006-01-01

In this case series we report four cases of patients with Down syndrome with symptoms consistent with obsessive compulsive disorder. Each patient experienced substantial reduction in compulsive behaviors with pharmacotherapy of an SSRI alone or with the addition of risperidone to SSRI therapy. None of the patients experienced significant side…

An Early Intervention Supporting the Literacy Learning of Children Experiencing Substantial Difficulty.

ERIC Educational Resources Information Center

Jackson, Jane B.; Paratore, Jeanne R.; Chard, David J.; Garnick, Sheila

1999-01-01

A study examined the degree to which eight teachers would faithfully implement an early literacy intervention plan. Teachers implemented the intervention with a high degree of fidelity and benefited from the community approach to intervention for struggling readers. Most children made substantial gains in phonemic blending and segmenting…

Using the Natural Language Paradigm (NLP) to increase vocalizations of older adults with cognitive impairments.

PubMed

Leblanc, Linda A; Geiger, Kaneen B; Sautter, Rachael A; Sidener, Tina M

2007-01-01

The Natural Language Paradigm (NLP) has proven effective in increasing spontaneous verbalizations for children with autism. This study investigated the use of NLP with older adults with cognitive impairments served at a leisure-based adult day program for seniors. Three individuals with limited spontaneous use of functional language participated in a multiple baseline design across participants. Data were collected on appropriate and inappropriate vocalizations with appropriate vocalizations coded as prompted or unprompted during baseline and treatment sessions. All participants experienced increases in appropriate speech during NLP with variable response patterns. Additionally, the two participants with substantial inappropriate vocalizations showed decreases in inappropriate speech. Implications for intervention in day programs are discussed.

Experiencing and Responding to Private Competition: The Importance of Subjectivity and Intermediate Outcomes

ERIC Educational Resources Information Center

Joshi, Priyadarshani

2016-01-01

Despite substantial growth in private schooling in developing countries, there has been little attention paid to the question of how public schools are experiencing and responding to competition in these contexts. To address this research gap, I collected primary survey data from two districts in Nepal and used descriptive and logistic regression…

Exposure to airborne amphibole structures and health risks: Libby, Montana.

PubMed

Price, Bertram

2008-10-01

Libby, Montana is the site of a large vermiculite deposit that was mined between 1920 and 1990 to extract vermiculite for commercial applications such as insulation, gardening products, and construction materials. The Libby vermiculite deposit also contains amphibole minerals including tremolite, actinolite, richterite, and winchite. Historically, Libby mine workers experienced high exposures to amphibole structures, and, as a group, have experienced the health consequences of those occupational exposures. It has been suggested that Libby residents also have been and continue to be exposed to amphibole structures released during the vermiculite mining operations and therefore are at increased risk for disease. The Agency for Toxic Substance and Disease Registry (ATSDR) conducted two epidemiological-type studies of residents living in Libby and the surrounding areas to assess these risks. The Environmental Protection Agency (EPA) collected and analyzed exposure data in Libby and used those data to project risks of asbestos-associated disease for Libby residents. The EPA has placed the Libby Asbestos Site, which includes the mine and the town of Libby, on its National Priority List of hazardous waste sites in need of clean up. This article presents a review of the exposure studies conducted in Libby and an analysis of health risks based on the data collected in those studies. Libby mine workers have experienced elevated levels of asbestos-associated disease as a consequence of their occupational exposures to amphibole structures. Libby residents' exposures typically are substantially lower than mine workers' historical exposures, and the health risk projections for residents are, accordingly, substantially lower.

Cyberinfrastructure: empowering a "third way" in biomedical research.

PubMed

Buetow, Kenneth H

2005-05-06

Biomedicine has experienced explosive growth, fueled in parts by the substantial increase of government support, continued development of the biotechnology industry, and the increasing adoption of molecular-based medicine. At its core, it is composed of fiercely independent, innovative, entrepreneurial individuals, organizations, and institutions. The field has developed unprecedented capacity to characterize biologic systems at their most fundamental levels with the use of tools and technologies almost unimaginable a generation ago. Biomedicine is at the precipice of unlocking the very essence of biologic life and enabling a new generation of medicine. Development and deployment of cyberinfrastructure may prove to be on the critical path to obtaining these goals.

Substantial changes in mastery perceptions of dementia caregivers with the placement of a care recipient.

PubMed

Infurna, Frank J; Gerstorf, Denis; Zarit, Steven H

2013-03-01

The current study examined how a key component of caregiving stress processes, global mastery perceptions, changes with placing the care recipient in a nursing home or institution. We also explored the role of primary stressors in accounting for mastery changes with placement and whether characteristics of the caregiver and care recipient moderate reactions to placement. We applied multiphase growth curve models to prospective longitudinal data from 271 caregivers in the Caregiver Stress and Coping Study who experienced placement of their care recipient. Using a time-to/from-placement metric, we found that caregivers typically experienced declines in mastery preceding placement, followed by a significant increase within 1 year after placement and further increases thereafter. Corresponding changes in primary stressors (role overload) mediated the placement-related increase in mastery. Caregivers who reported more depressive symptoms and activities of daily living/instrumental activities of daily living dependencies of the care recipient were more likely to experience larger placement-related increases in mastery perceptions. Our findings suggest that placement alters psychological resources of caregivers and this effect is driven by corresponding changes in primary stressors. Findings also underscore the importance of examining change processes across salient life events and transitions.

Community-based telemonitoring for hypertension management: practical challenges and potential solutions.

PubMed

Hovey, Lauren; Kaylor, Mary Beth; Alwan, Majd; Resnick, Helaine E

2011-10-01

Older adults residing in rural areas often lack convenient, patient-centered, community-based approaches to facilitate receipt of routine care to manage common chronic conditions. Without adequate access to appropriate disease management resources, the risk of seniors' experiencing acute events related to these common conditions increases substantially. Further, poorly managed chronic conditions are costly and place seniors at increased risk of institutionalization and permanent loss of independence. Novel, telehealth-based approaches to management of common chronic conditions like hypertension may not only improve the health of older adults, but may also lead to substantial cost savings associated with acute care episodes and institutionalization. The aim of this report is to summarize practical considerations related to operations and logistics of a unique community-based telemonitoring pilot study targeting rural seniors who utilize community-based senior centers. This article reviews the technological challenges encountered during the study and proposes solutions relevant to future research and implementation of telehealth in community-based, congregate settings.

Towards a New Way of Healing: Experienced Counsellors' Perceived Influences of Ch'i-Related Experiences on Counselling Practice in Taiwan

ERIC Educational Resources Information Center

Liou, Chin-Ping

2018-01-01

This narrative study explored how the experienced counsellors utilised the idea and practice of "ch'i" during counselling sessions. The data were co-constructed between the researcher and 12 senior counsellors with substantial "ch'i"-related experiences using a semi-structured in-depth interview method and were analysed…

Promoting the health of senior citizens

PubMed Central

Patterson, C; Feightner, J

1997-01-01

Canada is experiencing a dramatic increase in the number of older people in its population. Adopting strategies that involve physician actions, a societal approach and individual participation may substantially improve the health of senior citizens. This article presents ways to improve the quality of life and reduce the risk of premature death through manoeuvres that can be initiated by physicians in the context of the periodic health examination. The authors highlight the role of evidence in choosing the most appropriate interventions, speculate on areas of future importance and emphasize a societal approach to population health. PMID:9347782

μ-Opioid Receptor Gene A118 G Variants and Persistent Pain Symptoms Among Men and Women Experiencing Motor Vehicle Collision.

PubMed

Linnstaedt, Sarah D; Hu, JunMei; Bortsov, Andrey V; Soward, April C; Swor, Robert; Jones, Jeffrey; Lee, David; Peak, David; Domeier, Robert; Rathlev, Niels; Hendry, Phyllis; McLean, Samuel A

2015-07-01

The μ-opioid receptor 1 (OPRM1) binds endogenous opioids. Increasing evidence suggests that endogenous OPRM1 agonists released at the time of trauma may contribute to the development of posttraumatic musculoskeletal pain (MSP). In this prospective observational study, we evaluated the hypothesis that individuals with an AG or GG genotype at the OPRM1 A118 G allele, which results in a reduced response to opioids, would have less severe MSP 6 weeks after motor vehicle collision (MVC). Based on previous evidence, we hypothesized that this effect would be sex-dependent and most pronounced among women with substantial peritraumatic distress. European American men and women ≥ 18 years of age presenting to the emergency department after MVC and discharged to home after evaluation (N = 948) were enrolled. Assessments included genotyping and 6-week evaluation of overall MSP severity (0-10 numeric rating scale). In linear regression modeling, a significant A118 G Allele × Sex interaction was observed: an AG/GG genotype predicted reduced MSP severity among women with substantial peritraumatic distress (β = -.925, P = .014) but not among all women. In contrast, men with an AG/GG genotype experienced increased MSP severity at 6 weeks (β = .827, P = .019). Further studies are needed to understand the biologic mechanisms mediating observed sex differences in A118 G effects. These results suggest a sex-dependent mechanism by which an emotional response to trauma (distress) contributes to a biologic mechanism (endogenous opioid release) that increases MSP in the weeks after stress exposure. These results also support the hypothesis that endogenous opioids influence pain outcomes differently in men and women. Copyright © 2015 American Pain Society. Published by Elsevier Inc. All rights reserved.

Experiences of mental illness stigma, prejudice and discrimination: a review of measures.

PubMed

Brohan, Elaine; Slade, Mike; Clement, Sarah; Thornicroft, Graham

2010-03-25

There has been a substantial increase in research on mental illness related stigma over the past 10 years, with many measures in use. This study aims to review current practice in the survey measurement of mental illness stigma, prejudice and discrimination experienced by people who have personal experience of mental illness. We will identify measures used, their characteristics and psychometric properties. A narrative literature review of survey measures of mental illness stigma was conducted. The databases Medline, PsychInfo and the British Nursing Index were searched for the period 1990-2009. 57 studies were included in the review. 14 survey measures of mental illness stigma were identified. Seven of the located measures addressed aspects of perceived stigma, 10 aspects of experienced stigma and 5 aspects of self-stigma. Of the identified studies, 79% used one of the measures of perceived stigma, 46% one of the measures of experienced stigma and 33% one of the measures of self-stigma. All measures presented some information on psychometric properties. The review was structured by considering perceived, experienced and self stigma as separate but related constructs. It provides a resource to aid researchers in selecting the measure of mental illness stigma which is most appropriate to their purpose.

Long-term effects of parental divorce timing on depression: A population-based longitudinal study.

PubMed

Chun, Sung-Youn; Jang, Suk-Yong; Choi, Jae-Woo; Shin, Jaeyong; Park, Eun-Cheol

2016-09-08

We examined the long-term effects of parental divorce timing on depression using longitudinal data from the Korean Welfare Panel Study. Depression symptoms were measured using the 11 items of Center for Epidemiologic Scale for Depression (CES-D-11), and we categorized parental divorce timing into 'early childhood', 'adolescent' and 'none'. Although participants who experienced parental divorce during adolescence exhibited a significantly higher CES-D-11 score (p = .0468), 'early childhood' participants displayed the most increased CES-D-11 score compared to the control group (p = .0007). Conversely, among participants who were unsatisfied with their marriage, those who experienced parental divorce in early childhood showed lower CES-D-11 scores, while 'adolescent period' participants exhibited significantly higher CES-D-11 scores (p = .0131). We concluded that timing of parental divorce exerts substantial yet varied effects on long-term depression symptoms and future marriage satisfaction. © The Author(s) 2016.

The impact of conditional cash transfers on marriage and divorce.

PubMed

Bobonis, Gustavo J

2011-01-01

A growing number of less-developed countries have introduced conditional cash transfer programs in which funds are targeted to women. Economic models of the family suggest that these transfer programs may lead to marital turnover among program beneficiaries. Data from the experimental evaluation of the PROGRESA program in Mexico is used to provide new evidence on the short-run impacts of targeted transfers on couples' union dissolution and individuals' new union formation decisions. We find that, although the overall share of women in union does not change as a result of the program, marital turnover increases. Intact families eligible for the transfers experienced a modest (0.32 percentage points) increase in separation rates, with most of the effect concentrated among young and relatively educated women households. In contrast, young single women with low educational attainment levels experienced a substantial increase in new union formation rates. The marital transition patterns are consistent with the workhorse economic model of the marriage market-individuals with the greatest prospects to start new unions and those who may become more attractive in the marriage market are more likely to transition out of existing relationships and form new ones.

Trends in inequalities in child stunting in South Asia.

PubMed

Krishna, Aditi; Mejía-Guevara, Iván; McGovern, Mark; Aguayo, Victor; Subramanian, S V

2017-10-19

We analysed socio-economic inequalities in stunting in South Asia and investigated disparities associated with factors at the individual, caregiver, and household levels (poor dietary diversity, low maternal education, and household poverty). We used time-series analysis of data from 55,459 children ages 6-23 months from Demographic and Health Surveys in Bangladesh, India, Nepal, and Pakistan (1991-2014). Logistic regression models, adjusted for age, sex, birth order, and place of residency, examined associations between stunting and multiple types of socio-economic disadvantage. All countries had high stunting rates. Bangladesh and Nepal recorded the largest reductions-2.9 and 4.1 percentage points per year, respectively-compared to 1.3 and 0.6 percentage points in India and Pakistan, respectively. Socio-economic adversity was associated with increased risk of stunting, regardless of disadvantage type. Poor children with inadequate diets and with poorly educated mothers experienced greater risk of stunting. Although stunting rates declined in the most deprived groups, socio-economic differences were largely preserved over time and in some cases worsened, namely, between wealth quintiles. The disproportionate burden of stunting experienced by the most disadvantaged children and the worsening inequalities between socio-economic groups are of concern in countries with substantial stunting burdens. Closing the gap between best and worst performing countries, and between most and least disadvantaged groups within countries, would yield substantial improvements in stunting rates in South Asia. To do so, greater attention needs to be paid to addressing the social, economic, and political drivers of stunting with targeted efforts towards the populations experiencing the greatest disadvantage and child growth faltering. © 2017 John Wiley & Sons Ltd.

Disease and Development: Evidence from Hookworm Eradication in the American South*

PubMed Central

Bleakley, Hoyt

2013-01-01

This study evaluates the economic consequences of the successful eradication of hookworm disease from the American South. The hookworm-eradication campaign (c. 1910) began soon after (i) the discovery that a variety of health problems among Southerners could be attributed to the disease and (ii) the donation by John D. Rockefeller of a substantial sum to the effort. The Rockefeller Sanitary Commission (RSC) surveyed infection rates in the affected areas (eleven southern states) and found that an average of forty percent of school-aged children were infected with hookworm. The RSC then sponsored treatment and education campaigns across the region. Follow-up studies indicate that this campaign substantially reduced hookworm disease almost immediately. The sudden introduction of this treatment combines with the cross-area differences in pre-treatment infection rates to form the basis of the identification strategy. Areas with higher levels of hookworm infection prior to the RSC experienced greater increases in school enrollment, attendance, and literacy after the intervention. This result is robust to controlling for a variety of alternative factors, including differential trends across areas, changing crop prices, shifts in certain educational and health policies, and the effect of malaria eradication. No significant contemporaneous results are found for adults, who should have benefited less from the intervention owing to their substantially lower (prior) infection rates. A long-term follow-up of affected cohorts indicates a substantial gain in income that coincided with exposure to hookworm eradication. I also find evidence that eradication increased the return to schooling. PMID:24146438

Does Primary Productivity Turn Up the Volume? Exploring the Relationship Between Chlorophyll a and the Soundscape of Coral Reefs in the Pacific.

PubMed

Fisher-Pool, Pollyanna I; Lammers, Marc O; Gove, Jamison; Wong, Kevin B

2016-01-01

Chlorophyll is the basis for ecosystem productivity in most marine environments. We report on an ongoing effort to examine whether ambient sounds are tied to chlorophyll levels. We hypothesized that an increase in food-web available energy will be distributed across trophic levels, eventually reaching sound-producing animals and increasing acoustic levels. To test our hypothesis, we compared reef environments to explore links between soundscapes and chlorophyll a concentrations. The study sites resided in disparate oceanographic regimes that experienced substantially different oceanographic conditions. We anticipated that the results would show differing patterns of primary productivity between sites and therefore would be reflected in the soundscapes.

Back-to-back comparison of auto-fluorescence imaging (AFI) versus high resolution white light colonoscopy for adenoma detection.

PubMed

Moriichi, Kentaro; Fujiya, Mikihiro; Sato, Ryu; Watari, Jiro; Nomura, Yoshiki; Nata, Toshie; Ueno, Nobuhiro; Maeda, Shigeaki; Kashima, Shin; Itabashi, Kentaro; Ishikawa, Chisato; Inaba, Yuhei; Ito, Takahiro; Okamoto, Kotaro; Tanabe, Hiroki; Mizukami, Yusuke; Saitoh, Yusuke; Kohgo, Yutaka

2012-06-22

Some patients under close colonoscopic surveillance still develop colorectal cancer, thus suggesting the overlook of colorectal adenoma by endoscopists. AFI detects colorectal adenoma as a clear magenta, therefore the efficacy of AFI is expected to improve the detection ability of colorectal adenoma. The aim of this study is to determine the efficacy of AFI in detecting colorectal adenoma. This study enrolled 88 patients who underwent colonoscopy at Asahikawa Medical University and Kushiro Medical Association Hospital. A randomly selected colonoscopist first observed the sigmoid colon and rectum with conventional high resolution endosopy (HRE). Then the colonoscopist changed the mode to AFI and handed to the scope to another colonoscopist who knew no information about the HRE. Then the second colonoscopist observed the sigmoid colon and rectum. Each colonoscopist separately recorded the findings. The detection rate, miss rate and procedural time were assessed in prospective manner. The detection rate of flat and depressed adenoma, but not elevated adenoma, by AFI is significantly higher than that by HRE. In less-experienced endoscopists, AFI dramatically increased the detection rate (30.3%) and reduced miss rate (0%) of colorectal adenoma in comparison to those of HRE (7.7%, 50.0%), but not for experienced endoscopists. The procedural time of HRE was significantly shorter than that of AFI. AFI increased the detection rate and reduced the miss rate of flat and depressed adenomas. These advantages of AFI were limited to less-experienced endoscopists because experienced endoscopists exhibited a substantially high detection rate for colorectal adenoma with HRE.

Back-to-Back Comparison of Auto-Fluorescence Imaging (AFI) Versus High Resolution White Light Colonoscopy for Adenoma Detection

PubMed Central

2012-01-01

Background Some patients under close colonoscopic surveillance still develop colorectal cancer, thus suggesting the overlook of colorectal adenoma by endoscopists. AFI detects colorectal adenoma as a clear magenta, therefore the efficacy of AFI is expected to improve the detection ability of colorectal adenoma. The aim of this study is to determine the efficacy of AFI in detecting colorectal adenoma. Methods This study enrolled 88 patients who underwent colonoscopy at Asahikawa Medical University and Kushiro Medical Association Hospital. A randomly selected colonoscopist first observed the sigmoid colon and rectum with conventional high resolution endosopy (HRE). Then the colonoscopist changed the mode to AFI and handed to the scope to another colonoscopist who knew no information about the HRE. Then the second colonoscopist observed the sigmoid colon and rectum. Each colonoscopist separately recorded the findings. The detection rate, miss rate and procedural time were assessed in prospective manner. Results The detection rate of flat and depressed adenoma, but not elevated adenoma, by AFI is significantly higher than that by HRE. In less-experienced endoscopists, AFI dramatically increased the detection rate (30.3%) and reduced miss rate (0%) of colorectal adenoma in comparison to those of HRE (7.7%, 50.0%), but not for experienced endoscopists. The procedural time of HRE was significantly shorter than that of AFI. Conclusions AFI increased the detection rate and reduced the miss rate of flat and depressed adenomas. These advantages of AFI were limited to less-experienced endoscopists because experienced endoscopists exhibited a substantially high detection rate for colorectal adenoma with HRE. PMID:22726319

Increasing hygiene productivity.

PubMed

Levin, Roger P

2003-03-01

Dentists have many opportunities to expand the role of dental hygienists and provide patients with better oral health care, while increasing production and profits. But the proper business systems and verbal skills need to be incorporated. You must train hygienists to do all they can do for every patient. Begin with one service and add others, as the hygienists becomes familiar with each one. Set a goal of a 15% increase in production per year for the hygiene department. Clinicians using these strategies have experienced as much as a 100% to 200% increase in hygiene revenue during the first year of incorporating these services. An added benefit is that these dentists often see a substantial increase in dental treatment diagnosis and case acceptance. An effective and efficient hygiene department will often identify and help secure more than 50% of a doctor's production.

Linking salmon aquaculture synergies and trade-offs on ecosystem services to human wellbeing constituents.

PubMed

Outeiro, Luis; Villasante, Sebastian

2013-12-01

Salmon aquaculture has emerged as a successful economic industry generating high economic revenues to invest in the development of Chiloe region, Southern Chile. However, salmon aquaculture also consumes a substantial amount of ecosystem services, and the direct and indirect impacts on human wellbeing are still unknown and unexplored. This paper identifies the synergies and trade-offs caused by the salmon industry on a range of ecosystem services. The results show that large economic benefits due to the increase of provisioning ecosystem services are also causing a reduction on regulating and cultural services. Despite the improvement on average income and poverty levels experienced in communities closely associated with the sector, this progress is not large enough and social welfare did not improve substantially over the last decade. The rest of human wellbeing constituents in Chiloe region have not changed significantly compared to the development in the rest of the country.

Substantial Changes in Mastery Perceptions of Dementia Caregivers With the Placement of a Care Recipient

PubMed Central

2013-01-01

Objectives. The current study examined how a key component of caregiving stress processes, global mastery perceptions, changes with placing the care recipient in a nursing home or institution. We also explored the role of primary stressors in accounting for mastery changes with placement and whether characteristics of the caregiver and care recipient moderate reactions to placement. Method. We applied multiphase growth curve models to prospective longitudinal data from 271 caregivers in the Caregiver Stress and Coping Study who experienced placement of their care recipient. Results. Using a time-to/from-placement metric, we found that caregivers typically experienced declines in mastery preceding placement, followed by a significant increase within 1 year after placement and further increases thereafter. Corresponding changes in primary stressors (role overload) mediated the placement-related increase in mastery. Caregivers who reported more depressive symptoms and activities of daily living/instrumental activities of daily living dependencies of the care recipient were more likely to experience larger placement-related increases in mastery perceptions. Discussion. Our findings suggest that placement alters psychological resources of caregivers and this effect is driven by corresponding changes in primary stressors. Findings also underscore the importance of examining change processes across salient life events and transitions. PMID:22956053

Investigation of radiometric properties of the LANDSAT-4 multispectral scanner

NASA Technical Reports Server (NTRS)

Malila, W. A. (Principal Investigator); Rice, D. P.

1983-01-01

The radiometric data quality of the LANDSAT 4 multispectral scanner (MSS) was examined using several LANDSAT 4 frames. It was found that LANDSAT 4 MSS produces high-quality data of the caliber experienced with previous LANDSATS. For example, the detector equalization procedure worked well, leaving a residual banding effect of about 0.3 digital counts RMS, close to the theoretical minimum value of quantization error. Nevertheless, artifacts of the data were found, two of which were not experienced in previous MSS data. A low-level coherent noise effect was observed in all bands, with a magnitude of about 0.5 digital counts and a frequency of approximately 28 KHz (representing a wavelength of about 3.6 pixels); a substantial increase in processing complexity would be required to reduce this artifact in the data. Also, a substantial scan-length variation (of up to six pixels) was noted in MSS data when the TM sensor was operating; the LANDSAT 4 correction algorithms being applied routinely by the EROS Data Center to produce a p-type data should remove most of this variation. Between-satellite calibrations were examined in paired LANDSAT 3 and LANDSAT 4 MSS data sets, which were closely matched in acquisition time and place. Radiometric comparisons showed that all bands were highly linear in digital counts, and a well-determined linear transformation between the MSS's was established.

The role of protein digestibility and antacids on food allergy outcomes

PubMed Central

Untersmayr, Eva; Jensen-Jarolim, Erika

2010-01-01

Digestion assays with simulated gastric fluid have been introduced for characterization of food proteins to imitate the effect of stomach proteolysis on dietary compounds in vitro. By using these tests, dietary proteins can be categorized as digestion-resistant class 1 (true allergens triggering direct oral sensitization) or as labile class 2 allergens (nonsensitizing elicitors). Thus the results of these digestion assays mirror situations of intact gastric proteolysis. Alterations in the gastric milieu are frequently experienced during a lifetime either physiologically in the very young and the elderly or as a result of gastrointestinal pathologies. Additionally, acid-suppression medications are frequently used for treatment of dyspeptic disorders. By increasing the gastric pH, they interfere substantially with the digestive function of the stomach, leading to persistence of labile food protein during gastric transit. Indeed, both murine and human studies reveal that antiulcer medication increases the risk of food allergy induction. Gastric digestion substantially decreases the potential of food proteins to bind IgE, which increases the threshold dose of allergens required to elicit symptoms in patients with food allergy. Thus antiulcer agents impeding gastric protein digestion have a major effect on the sensitization and effector phase of food allergy. PMID:18539189

The Obama plan: more regulation, unsustainable spending.

PubMed

Antos, Joseph; Wilensky, Gail; Kuttner, Hanns

2008-01-01

The health reform plan put forth by Sen. Barack Obama (D-IL) focuses on expanding insurance coverage and provides new subsidies to individuals, small businesses, and businesses experiencing catastrophic expenses. It greatly increases the federal regulation of private insurance but does not address the core economic incentives that drive health care spending. This omission along with the very substantial short-term savings claimed raise serious questions about its fiscal sustainability. Heavy regulation coupled with a fallback National Health Plan and a play-or-pay financing choice also raise questions about the future of the employer insurance market.

A descriptive analysis of the 2008 credit crisis on multistate healthcare systems: what impact did it have on their financial performance?

PubMed

McCue, Michael J

2010-01-01

Due to the recent credit crisis and recession of 2008, hospitals experienced substantial losses in their investment portfolios. The author analyzed key financial accounts of 15 large, multistate healthcare systems that measured their changes in value of their investments, changes in net assets, liquidity ratios, and other performance ratios. Overall, he found that the majority of these systems did incur financial losses in their investment portfolios; however, for the majority of these systems, their liquidity and cash flow margin ratios declined slightly whereas their capital expenditure and community benefits increased.

Does the earned income tax credit increase children's weight? The impact of policy-driven income on childhood obesity.

PubMed

Jo, Young

2018-07-01

I exploit substantial increases in the earned income tax credit to study how a policy-driven change in family income affects childhood obesity. Using the National Longitudinal Survey of Youth 1979, my difference-in-differences estimates indicate that the probability of being obese increased by 3 percentage points among children whose families experienced a greater income shock. A further investigation suggests that a reduction in maternal time with children played a greater role in children's weight gain than income. The paper's finding shows that a program that is not designed for health purposes, such as earned income tax credit, can have unintended effects on health outcomes. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

Military sexual trauma among homeless veterans.

PubMed

Pavao, Joanne; Turchik, Jessica A; Hyun, Jenny K; Karpenko, Julie; Saweikis, Meghan; McCutcheon, Susan; Kane, Vincent; Kimerling, Rachel

2013-07-01

Military sexual trauma (MST) is the Veteran Health Administration's (VHA) term for sexual assault and/or sexual harassment that occurs during military service. The experience of MST is associated with a variety of mental health conditions. Preliminary research suggests that MST may be associated with homelessness among female Veterans, although to date MST has not been examined in a national study of both female and male homeless Veterans. To estimate the prevalence of MST, examine the association between MST and mental health conditions, and describe mental health utilization among homeless women and men. National, cross-sectional study of 126,598 homeless Veterans who used VHA outpatient care in fiscal year 2010. All variables were obtained from VHA administrative databases, including MST screening status, ICD-9-CM codes to determine mental health diagnoses, and VHA utilization. Of homeless Veterans in VHA, 39.7 % of females and 3.3 % of males experienced MST. Homeless Veterans who experienced MST demonstrated a significantly higher likelihood of almost all mental health conditions examined as compared to other homeless women and men, including depression, posttraumatic stress disorder, other anxiety disorders, substance use disorders, bipolar disorders, personality disorders, suicide, and, among men only, schizophrenia and psychotic disorders. Nearly all homeless Veterans had at least one mental health visit and Veterans who experienced MST utilized significantly more mental health visits compared to Veterans who did not experience MST. A substantial proportion of homeless Veterans using VHA services have experienced MST, and those who experienced MST had increased odds of mental health diagnoses. Homeless Veterans who had experienced MST had higher intensity of mental health care utilization and high rates of MST-related mental health care. This study highlights the importance of trauma-informed care among homeless Veterans and the success of VHA homeless programs in providing mental health care to homeless Veterans.

Hydrogen peroxide production is affected by oxygen levels in mammalian cell culture.

PubMed

Maddalena, Lucas A; Selim, Shehab M; Fonseca, Joao; Messner, Holt; McGowan, Shannon; Stuart, Jeffrey A

2017-11-04

Although oxygen levels in the extracellular space of most mammalian tissues are just a few percent, under standard cell culture conditions they are not regulated and are often substantially higher. Some cellular sources of reactive oxygen species, like NADPH oxidase 4, are sensitive to oxygen levels in the range between 'normal' physiological (typically 1-5%) and standard cell culture (up to 18%). Hydrogen peroxide in particular participates in signal transduction pathways via protein redox modifications, so the potential increase in its production under standard cell culture conditions is important to understand. We measured the rates of cellular hydrogen peroxide production in some common cell lines, including C2C12, PC-3, HeLa, SH-SY5Y, MCF-7, and mouse embryonic fibroblasts (MEFs) maintained at 18% or 5% oxygen. In all instances the rate of hydrogen peroxide production by these cells was significantly greater at 18% oxygen than at 5%. The increase in hydrogen peroxide production at higher oxygen levels was either abolished or substantially reduced by treatment with GKT 137831, a selective inhibitor of NADPH oxidase subunits 1 and 4. These data indicate that oxygen levels experienced by cells in culture influence hydrogen peroxide production via NADPH oxidase 1/4, highlighting the importance of regulating oxygen levels in culture near physiological values. However, we measured pericellular oxygen levels adjacent to cell monolayers under a variety of conditions and with different cell lines and found that, particularly when growing at 5% incubator oxygen levels, pericellular oxygen was often lower and variable. Together, these observations indicate the importance, and difficulty, of regulating oxygen levels experienced by cells in culture. Copyright © 2017 Elsevier Inc. All rights reserved.

Hypnosis in contemporary medicine.

PubMed

Stewart, James H

2005-04-01

Hypnosis became popular as a treatment for medical conditions in the late 1700s when effective pharmaceutical and surgical treatment options were limited. To determine whether hypnosis has a role in contemporary medicine, relevant trials and a few case reports are reviewed. Despite substantial variation in techniques among the numerous reports, patients treated with hypnosis experienced substantial benefits for many different medical conditions. An expanded role for hypnosis and a larger study of techniques appear to be indicated.

Predictive adaptive responses: Condition-dependent impact of adult nutrition and flight in the tropical butterfly Bicyclus anynana.

PubMed

Saastamoinen, Marjo; van der Sterren, Dominique; Vastenhout, Nienke; Zwaan, Bas J; Brakefield, Paul M

2010-12-01

The experience of environmental stress during development can substantially affect an organism's life history. These effects are often mainly negative, but a growing number of studies suggest that under certain environmental conditions early experience of such stress may yield individuals that are less sensitive to environmental stress later on in life. We used the butterfly Bicyclus anynana to study the effects of limited larval and adult food and forced flight on individual performance measured as reproduction and adult life span. Larvae exposed to food stress showed longer development and produced smaller adults. Thus, they were not able to fully compensate for the food deprivation during development. Females that experienced food stress during development did not increase tolerance for adult food limitation. However, females exposed to food stress during development coped better with forced flight compared with the control group. The apparent absence of costs of flight in poor-quality females may be a by-product of an altered body allocation, as females experiencing both food stress treatments had increased thorax ratios, compared with controls, and increased flight performances. The results reveal an important plasticity component to variation in flight performance and suggest that the cost of flight depends on an individual's internal condition.

Point of Sale Scanner Data for Rapid Surveillance of the E-cigarette Market.

PubMed

Day, Hannah R; Ambrose, Bridget K; Schroeder, Megan J; Corey, Catherine G

2017-01-01

Describe e-cigarette sales trends and market share from U.S. convenience stores and mass market retailers. We used Nielsen Scantrack to calculate U.S. e-cigarette sales market share from convenience and mass market channels during the 4-week period ending 1/19/13 through the period ending 12/19/15. Internet searches were used to supplement Nielsen product information. From 2013 to 2015, rechargeable e-cigarette brands VUSE and MarkTen experienced the largest growth in Nielsen channels. E-liquid and tank type brands Vapin Plus and Haus experienced growth although their Nielsen market share is small compared to other brands. Sales of brands with high labeled nicotine content (according to packaging or website) increased. Fruit-flavored sales increased rapidly in Nielsen, yet still represent a minority of market share in these channels. Market-leading e-cigarette brands changed substantially in Nielsen channels from 2013 to 2015. Brand leaders in these channels are now owned by tobacco companies. Changes in labelled nicotine content and fruit-flavored products and product types suggest that as e-cigarette use increases, convenience store and mass market channels are offering new products to meet consumer preferences; however, Nielsen channels do not represent the entire e-cigarette marketplace.

The cumulative burden borne by offspring whose mothers were sexually abused as children: descriptive results from a multigenerational study.

PubMed

Noll, Jennie G; Trickett, Penelope K; Harris, William W; Putnam, Frank W

2009-03-01

This multigenerational study empirically demonstrates the extent to which offspring whose parents experienced childhood abuse are at increased risk of being abused or neglected. Females with substantiated childhood sexual abuse and non abused comparison females were assessed at six points spanning 18 years in a prospective, longitudinal study. Non abusing parents or caregivers and offspring were also assessed. Descriptive results indicate that offspring born to mothers with histories of sexual abuse were more likely to be born preterm, have a teenage mother, and be involved in protective services. Abused mothers were more likely to be high-school dropouts, be obese, and have experienced psychiatric problems, substance dependence, and domestic violence. Results provide evidence for the advantages of intervention and prevention programs for victims of childhood maltreatment and their families. Primary prevention/intervention efforts extending throughout development and focusing on the cumulative risk to offspring will likely improve victim outcomes and curtail intergenerational transmission of adversity.

Stream power framework for predicting geomorphic change: The 2013 Colorado Front Range flood

NASA Astrophysics Data System (ADS)

Yochum, Steven E.; Sholtes, Joel S.; Scott, Julian A.; Bledsoe, Brian P.

2017-09-01

The Colorado Front Range flood of September 2013 induced a diverse range of geomorphic changes along numerous stream corridors, providing an opportunity to assess responses to a large flood in a semiarid landscape. We defined six classes of geomorphic change related to peak unit stream power and valley confinement for 531 stream reaches over 226 km, spanning a gradient of channel scales and slope. Geomorphic change was generally driven by erosion of channel margins in confined reaches and by a combination of deposition and erosion in unconfined reaches. The magnitude of geomorphic change typically increased with unit stream power (ω), with greater responses observed in unconfined channels. Cumulative logit modeling indicated that total stream power or unit stream power, unit stream power gradient, and valley confinement are significant predictors of geomorphic response for this flood event. Based on this dataset, thresholds for geomorphic adjustment were defined. For channel slopes < 3%, we noted a credible potential for substantial channel widening with ω > 230 W/m2 (16 lb/ft-s; at least 10% of the investigated sites experienced substantial channel widening) and a credible potential for avulsions, braiding, and loss of adjacent road embankments associated with ω > 480 W/m2 (33 lb/ft-s; at least 10% of the investigated sites experienced such geomorphic change). Infrequent to numerous eroded banks were very likely with ω > 700 W/m2 (48 lb/ft-s), with substantial channel widening or major geomorphic change shifting from credible to likely. Importantly, in reaches where there were large reductions in ω as the valley form shifted from confined to relatively unconfined, large amounts of deposition-induced, reach-scale geomorphic change occurred in some locations at relatively low ω. Additionally, alluvial channels with slopes > 3% had greater resistance to geomorphic change, likely caused by armoring by larger bed material and increased flow resistance from enhanced bedforms. Finally, we describe how these results can potentially be used by practitioners for assessing the risk of geomorphic change when evaluating current or planned conditions.

Groin Problems in Male Soccer Players Are More Common Than Previously Reported.

PubMed

Harøy, Joar; Clarsen, Ben; Thorborg, Kristian; Hölmich, Per; Bahr, Roald; Andersen, Thor Einar

2017-05-01

The majority of surveillance studies in soccer have used a time-loss injury definition, and many groin problems result from overuse, leading to gradually increasing pain and/or reduced performance without necessarily causing an absence from soccer training or match play. Thus, the magnitude of groin problems in soccer has probably been underestimated in previous studies based on traditional injury surveillance methods. To investigate the prevalence of groin problems among soccer players of both sexes and among male soccer players at different levels of play through a new surveillance method developed to capture acute and overuse problems. Descriptive epidemiology study. We registered groin problems during a 6-week period of match congestion using the Oslo Sports Trauma Research Center Overuse Injury Questionnaire. A total of 240 players from 15 teams across different levels of play and from both sexes were included, and they responded to the weekly questionnaire. We calculated the average weekly prevalence of all groin problems and substantial groin problems. Of the 240 players, 112 male players (59%) and 20 female players (45%) reported at least 1 episode of groin problems. The average weekly prevalence of any groin problem and substantial groin problem for all male players was 29% (range, 23%-32% across different levels) and 10% (7%-13%), respectively. Elite male players had an increased risk of experiencing groin problems (odds ratio: 3.1, 95% CI: 1.5-6.4, P = .03) compared with elite female players. There was no difference in the risk of experiencing groin problems among elite, subelite, and amateur male players. For substantial problems, there was no difference between elite male and elite female players or among levels of play for senior male soccer players. We found a high prevalence of groin problems among male soccer players during a period with match congestion. Time-loss definition as used in previous injury surveillance studies captured only one-third of the male groin problems registered with the new method. Elite male players had 3 times' higher risk of reporting groin problems as compared with elite female players, while playing level did not influence the risk of reporting a groin problem among males.

A psychophysiological investigation of sexual arousal in women with lifelong vaginismus.

PubMed

Cherner, Rebecca A; Reissing, Elke D

2013-05-01

Relatively little is known about the subjective reactions of women with lifelong vaginismus to erotic stimuli and genital arousal has never been investigated. Reports of maladaptive cognitions and fears regarding sexuality and intercourse suggest that anxiety may interfere with sexual arousal in women with vaginismus. To examine the genital and subjective responses to sexually explicit film stimuli of women with lifelong vaginismus compared with women with lifelong dyspareunia and women with no pain. Forty-five women (15 vaginismus, 15 dyspareunia, and 15 no pain) viewed two neutral and two erotic film sets, one depicting sexual activity without vaginal penetration and the other depicting intercourse, over two testing sessions. Vulvar temperature was recorded using an infrared camera. Participants completed a measure of subjective responses after viewing each film. All groups experienced increased vulvar temperature during the erotic films regardless of activity depicted. In response to the erotic films, the vaginismus group reported less mental arousal than the no-pain group and a range of negative subjective responses, including threat and disgust. Overall, participants showed concordance between peak subjective sexual arousal and temperature change from baseline to peak arousal. Despite negative subjective responses, women with vaginismus responded with increased genital sexual arousal to erotic films. The resilience of genital arousal may have resulted from moderate levels of anxiety experienced in the laboratory setting facilitating sexual response regardless of subjective appraisal; however, anxiety experienced in a dyadic context may interfere more substantially. © 2013 International Society for Sexual Medicine.

Tumbling and spaceflight: the Gemini VIII experience.

PubMed

Mohler, S R; Nicogossian, A E; McCormack, P D; Mohler, S R

1990-01-01

A malfunctioning orbital flight attitude thruster during the flight of Gemini VIII led to acceleration forces on astronauts Neil Armstrong (commander) and David Scott (pilot) that created the potential for derogation of oculo-vestibular and eye-hand coordination effects. The spacecraft attained an axial tumbling rotation of 50 rpm and would have exceeded this had not the commander accurately diagnosed the problem and taken immediate corrective action. By the time counter-measure controls were applied, both astronauts were experiencing vertigo and the physiological effects of the tumbling acceleration. Data from the recorders reveal that one astronaut experienced -Gy of 0.92 G-units, and the other +Gy of 0.92 for approximately 46 s. Both received a -Gz of 0.89 G-units from the waist up with a +Gz of 0.05 from the waist down. A substantial increase of time and/or an increase in rpm would ultimately have produced incapacitation of both astronauts. NASA corrected the Gemini thruster problem by changing the ignition system wiring. Future space-craft undertaking long-term missions could be equipped with unambiguous thruster fault displays and could have computer-controlled automatic cutoffs to control excessive thruster burns.

Rapid thinning and collapse of lake calving Yakutat Glacier, Southeast Alaska

NASA Astrophysics Data System (ADS)

Trussel, Barbara Lea

Glaciers around the globe are experiencing a notable retreat and thinning, triggered by atmospheric warming. Tidewater glaciers in particular have received much attention, because they have been recognized to contribute substantially to global sea level rise. However, lake calving glaciers in Alaska show increasingly high thinning and retreat rates and are therefore contributors to sea level rise. The number of such lake calving systems is increasing worldwide as land-terminating glaciers retreat into overdeepened basins and form proglacial lakes. Yakutat Glacier in Southeast Alaska is a low elevation lake calving glacier with an accumulation to total area ratio of 0.03. It experienced rapid thinning of 4.43 +/- 0.06 m w.e. yr-1 between 2000-2010 and terminus retreat of over 15 km since the beginning of the 20th century. Simultaneously, adjacent Yakutat Icefield land-terminating glaciers thinned at lower but still substantial rates (3.54 +/- 0.06 m w.e. yr -1 for the same time period), indicating lake calving dynamics help drive increased mass loss. Yakutat Glacier sustained a ˜3 km long floating tongue for over a decade, which started to disintegrate into large tabular icebergs in 2010. Such floating tongues are rarely seen on temperate tidewater glaciers. The floating ice was weakened by surface ablation, which then allowed rifts to form and intersect. Ice velocity from GPS measurements showed that the ice on the floating tongue was moving substantially faster than grounded ice, which was attributed to rift opening between the floating and grounded ice. Temporal variations of rift opening were determined from time-lapse imagery, and correlated well with variations in ice speeds. Larger rift opening rates occurred during and after precipitation or increased melt episodes. Both of these events increased subglacial discharge and could potentially increase the subaqueous currents towards the open lake and thus increase drag on the ice underside. Simultaneously, increased water input may cause lake level in rifts to rise resulting in faster rift propagation and spreading. Similar formation and disintegration of floating tongues are expected to occur in the glacier's future, as the ice divide lies below the current lake level. In addition to calving retreat, Yakutat Glacier is rapidly thinning, which lowers its surface and therefore exposes the ice to warmer air temperatures causing increased thinning. Even under a constant climate, this positive feedback mechanism would force Yakutat Glacier to quickly retreat and mostly disappear. Simulations of future mass loss were run for two scenarios, keeping the current climate and forcing it with a projected warming climate. Results showed that over 95% of the glacier ice will have disappeared by 2120 or 2070 under a constant vs projected climate, respectively. For the first few decades, the glacier will be able to maintain its current thinning rate by retreating and thus losing areas of lowest elevation. However, once higher elevations have thinned substantially, the glacier cannot compensate any more to maintain a constant thinning rate and transfers into an unstable run-away situation. To stop this collapse and transform Yakutat Glacier into equilibrium in its current geometry, air temperatures would have to drop by 1.5 K or precipitation would have to increase by more than 50%. An increase in precipitation alone is unlikely to lead to a stable configuration, due to the very small current accumulation area.

Empathy promotes altruistic behavior in economic interactions

PubMed Central

Klimecki, Olga M.; Mayer, Sarah V.; Jusyte, Aiste; Scheeff , Jonathan; Schönenberg, Michael

2016-01-01

What are the determinants of altruism? While economists assume that altruism is mainly driven by fairness norms, social psychologists consider empathy to be a key motivator for altruistic behavior. To unite these two theories, we conducted an experiment in which we compared behavior in a standard economic game that assesses altruism (the so-called Dictator Game) with a Dictator Game in which participants’ behavioral choices were preceded either by an empathy induction or by a control condition without empathy induction. The results of this within-subject manipulation show that the empathy induction substantially increased altruistic behavior. Moreover, the increase in experienced empathy predicted over 40% of the increase in sharing behavior. These data extend standard economic theories that altruism is based on fairness considerations, by showing that empathic feelings can be a key motivator for altruistic behavior in economic interactions. PMID:27578563

Solar and anthropogenic forcing of tropical hydrology

NASA Astrophysics Data System (ADS)

Shindell, Drew T.; Faluvegi, Greg; Miller, Ron L.; Schmidt, Gavin A.; Hansen, James E.; Sun, Shan

2006-12-01

Holocene climate proxies suggest substantial correlations between tropical meteorology and solar variations, but these have thus far not been explained. Using a coupled ocean-atmosphere-composition model forced by sustained multi-decadal irradiance increases, we show that greater tropical temperatures alter the hydrologic cycle, enhancing the climatological precipitation maxima in the tropics while drying the subtropical subsidence regions. The shift is enhanced by tropopause region ozone increases, and the model captures the pattern inferred from paleoclimate records. The physical process we describe likely affected past civilizations, including the Maya, Moche, and Ancestral Puebloans who experienced drought coincident with increased irradiance during the late medieval (~900-1250). Similarly, decreased irradiance may have affected cultures via a weakened monsoon during the Little Ice Age (~1400-1750). Projections of 21st-century climate change yield hydrologic cycle changes via similar processes, suggesting a strong likelihood of increased subtropical drought as climate warms.

The More or the Better? How Sex Contributes to Life Satisfaction.

PubMed

Schmiedeberg, Claudia; Huyer-May, Bernadette; Castiglioni, Laura; Johnson, Matthew D

2017-02-01

Much cross-sectional research documented associations between sexuality and life satisfaction, but very little longitudinal research on the topic has considered whether changes in sexuality and life satisfaction unfold together over time. Using data from 5582 individuals in partnerships surveyed across 5786 intimate relationships (providing 18,712 observations for analysis) during five waves of the German Family Panel (pairfam), this study examined whether intraindividual changes in sexual frequency and satisfaction were associated with corresponding intraindividual changes in life satisfaction. Fixed effects regression modeling results showed that individuals reported a greater increase (decrease) in life satisfaction when they also experienced a more substantial increase (decrease) in sexual frequency and satisfaction. This finding was consistent for men and women. This study contributes to the literature by documenting that naturally occurring increases in sexual frequency and satisfaction over time predicted corresponding increases in life satisfaction.

Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes

PubMed Central

Huang, Shengfeng; Chen, Zelin; Yan, Xinyu; Yu, Ting; Huang, Guangrui; Yan, Qingyu; Pontarotti, Pierre Antoine; Zhao, Hongchen; Li, Jie; Yang, Ping; Wang, Ruihua; Li, Rui; Tao, Xin; Deng, Ting; Wang, Yiquan; Li, Guang; Zhang, Qiujin; Zhou, Sisi; You, Leiming; Yuan, Shaochun; Fu, Yonggui; Wu, Fenfang; Dong, Meiling; Chen, Shangwu; Xu, Anlong

2014-01-01

Vertebrates diverged from other chordates ~500 Myr ago and experienced successful innovations and adaptations, but the genomic basis underlying vertebrate origins are not fully understood. Here we suggest, through comparison with multiple lancelet (amphioxus) genomes, that ancient vertebrates experienced high rates of protein evolution, genome rearrangement and domain shuffling and that these rates greatly slowed down after the divergence of jawed and jawless vertebrates. Compared with lancelets, modern vertebrates retain, at least relatively, less protein diversity, fewer nucleotide polymorphisms, domain combinations and conserved non-coding elements (CNE). Modern vertebrates also lost substantial transposable element (TE) diversity, whereas lancelets preserve high TE diversity that includes even the long-sought RAG transposon. Lancelets also exhibit rapid gene turnover, pervasive transcription, fastest exon shuffling in metazoans and substantial TE methylation not observed in other invertebrates. These new lancelet genome sequences provide new insights into the chordate ancestral state and the vertebrate evolution. PMID:25523484

Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes.

PubMed

Huang, Shengfeng; Chen, Zelin; Yan, Xinyu; Yu, Ting; Huang, Guangrui; Yan, Qingyu; Pontarotti, Pierre Antoine; Zhao, Hongchen; Li, Jie; Yang, Ping; Wang, Ruihua; Li, Rui; Tao, Xin; Deng, Ting; Wang, Yiquan; Li, Guang; Zhang, Qiujin; Zhou, Sisi; You, Leiming; Yuan, Shaochun; Fu, Yonggui; Wu, Fenfang; Dong, Meiling; Chen, Shangwu; Xu, Anlong

2014-12-19

Vertebrates diverged from other chordates ~500 Myr ago and experienced successful innovations and adaptations, but the genomic basis underlying vertebrate origins are not fully understood. Here we suggest, through comparison with multiple lancelet (amphioxus) genomes, that ancient vertebrates experienced high rates of protein evolution, genome rearrangement and domain shuffling and that these rates greatly slowed down after the divergence of jawed and jawless vertebrates. Compared with lancelets, modern vertebrates retain, at least relatively, less protein diversity, fewer nucleotide polymorphisms, domain combinations and conserved non-coding elements (CNE). Modern vertebrates also lost substantial transposable element (TE) diversity, whereas lancelets preserve high TE diversity that includes even the long-sought RAG transposon. Lancelets also exhibit rapid gene turnover, pervasive transcription, fastest exon shuffling in metazoans and substantial TE methylation not observed in other invertebrates. These new lancelet genome sequences provide new insights into the chordate ancestral state and the vertebrate evolution.

A Case Report: Subanesthetic Ketamine Infusion for Treatment of Cancer-Related Pain Produces Urinary Urge Incontinence.

PubMed

Vickers, Barbara A; Lee, Wayne; Hunsberger, Joann

2017-05-01

Oncology patients undergoing treatment can experience substantial pain related to their disease or prescribed therapy. Ketamine infusions at subanesthetic doses have been used at our institution to supplement the pain management regimens of 262 patients. We present 2 cases in which young adult patients being treated with subanesthetic ketamine for cancer-related pain experienced urinary urgency and incontinence after initiation or increase of the ketamine infusion. This adverse effect has not been reported previously at this dosing range. These case reports suggest that subanesthetic ketamine infusions may cause side effects that previously have been reported only at anesthetic or abuse doses.

Age-period-cohort analysis of infectious disease mortality in urban-rural China, 1990-2010.

PubMed

Li, Zhi; Wang, Peigang; Gao, Ge; Xu, Chunling; Chen, Xinguang

2016-03-31

Although a number of studies on infectious disease trends in China exist, these studies have not distinguished the age, period, and cohort effects simultaneously. Here, we analyze infectious disease mortality trends among urban and rural residents in China and distinguish the age, period, and cohort effects simultaneously. Infectious disease mortality rates (1990-2010) of urban and rural residents (5-84 years old) were obtained from the China Health Statistical Yearbook and analyzed with an age-period-cohort (APC) model based on Intrinsic Estimator (IE). Infectious disease mortality is relatively high at age group 5-9, reaches a minimum in adolescence (age group 10-19), then rises with age, with the growth rate gradually slowing down from approximately age 75. From 1990 to 2010, except for a slight rise among urban residents from 2000 to 2005, the mortality of Chinese residents experienced a substantial decline, though at a slower pace from 2005 to 2010. In contrast to the urban residents, rural residents experienced a rapid decline in mortality during 2000 to 2005. The mortality gap between urban and rural residents substantially narrowed during this period. Overall, later birth cohorts experienced lower infectious disease mortality risk. From the 1906-1910 to the 1941-1945 birth cohorts, the decrease of mortality among urban residents was significantly faster than that of subsequent birth cohorts and rural counterparts. With the rapid aging of the Chinese population, the prevention and control of infectious disease in elderly people will present greater challenges. From 1990 to 2010, the infectious disease mortality of Chinese residents and the urban-rural disparity have experienced substantial declines. However, the re-emergence of previously prevalent diseases and the emergence of new infectious diseases created new challenges. It is necessary to further strengthen screening, immunization, and treatment for the elderly and for older cohorts at high risk.

Beaconing Signalization Substantially Reduces Blind Pedestrians’ Veer on Snow-Covered Pavement

PubMed Central

Guth, David A.; Long, Richard G.; Kim, Dae Shik; Robertson, Elizabeth A.; Reesor, Abbie L.; Bacik, Catherine J.; Eckert, Jaclyn M.

2017-01-01

Veering outside of crosswalks is a common problem experienced by individuals who are blind. One technology found to be effective for reducing this veer when other guidance cues are absent is audible beaconing. However, veering in general and veering from crosswalks in particular have been studied primarily on smooth, flat walking surfaces such as clear pavement. This experiment compared veering on clear pavement with veering on snow-covered pavement, with and without audible beaconing. Eleven blind participants traveling with long canes attempted to walk a straight path for 72 ft (21.9 m), a typical length of a six-lane crosswalk. Beaconing substantially reduced veering at 36 ft (11.0 m) and 72 ft from the starting point and enabled participants to remain within a simulated crosswalk. Walking on snow was not found to affect veering but did increase the number of steps taken. The findings suggest that in snowy and clear conditions alike, audible beaconing is an effective wayfinding tool for intersections equipped with accessible pedestrian signals. PMID:29307955

Beaconing Signalization Substantially Reduces Blind Pedestrians' Veer on Snow-Covered Pavement.

PubMed

Guth, David A; Long, Richard G; Kim, Dae Shik; Robertson, Elizabeth A; Reesor, Abbie L; Bacik, Catherine J; Eckert, Jaclyn M

2017-01-01

Veering outside of crosswalks is a common problem experienced by individuals who are blind. One technology found to be effective for reducing this veer when other guidance cues are absent is audible beaconing. However, veering in general and veering from crosswalks in particular have been studied primarily on smooth, flat walking surfaces such as clear pavement. This experiment compared veering on clear pavement with veering on snow-covered pavement, with and without audible beaconing. Eleven blind participants traveling with long canes attempted to walk a straight path for 72 ft (21.9 m), a typical length of a six-lane crosswalk. Beaconing substantially reduced veering at 36 ft (11.0 m) and 72 ft from the starting point and enabled participants to remain within a simulated crosswalk. Walking on snow was not found to affect veering but did increase the number of steps taken. The findings suggest that in snowy and clear conditions alike, audible beaconing is an effective wayfinding tool for intersections equipped with accessible pedestrian signals.

Financial Management and Young Australian Workers

ERIC Educational Resources Information Center

Dowling, Nicki; Hoiles, Lauren; Corney, Tim; Clark, David

2008-01-01

In two studies of young Australian workers, participants generally displayed positive attitudes towards financial management practices; however, a substantial proportion failed to display positive financial management practices, experienced financial problems and dissatisfaction, and reported low rates of seeking financial assistance, particularly…

Polyurethane foam for roadway stabilization NH Route 129, Loudon, NH.

DOT National Transportation Integrated Search

2016-12-12

This report summarizes the evaluation of the performance of polyurethane foam as a method of roadway : stabilization for a rural roadway experiencing substantial frost heaving. : NHDOT is responsible for many roads which have evolved from gravel road...

Polyurethane foam for roadway stabilization NH route 129, Loudon, NH.

DOT National Transportation Integrated Search

2016-12-12

This report summarizes the evaluation of the performance of polyurethane foam as a method of roadway : stabilization for a rural roadway experiencing substantial frost heaving. : NHDOT is responsible for many roads which have evolved from gravel road...

Air Traffic Control: Status of FAA's Standard Terminal Automation Replacement System Project

DOT National Transportation Integrated Search

1997-03-01

Since the early 1980s, FAA's modernization efforts have experienced lengthy : schedule delays and substantial cost overruns. Because of such problems, in : 1994, FAA restructured its acquisition of the Terminal Advanced Automation : System into more ...

Paradoxical topiramate-induced hyperphagia successfully treated with phentermine in a woman with migraine.

PubMed

Johnson, Jacinta L; Rolan, Paul E

2015-08-01

We report a 49-year-old female migraineur who experienced paradoxical hyperphagia and concurrent intrusive food thoughts leading to rapid weight gain and a substantial increase in waist circumference. A significant reduction in migraine frequency was also observed during topiramate treatment, a widely used migraine prophylactic agent which is generally associated with weight loss. Withdrawal of topiramate saw appetite return to baseline levels, however, migraine frequency was again increased. Topiramate was reinitiated in combination with phentermine, a drug indicated for weight management, without reoccurrence of adverse effects. Migraine control was maintained and progressive weight loss ensued. Combination treatment with phentermine may be a useful strategy should other patients experience this adverse reaction while gaining therapeutic anti-migraine benefit from topiramate. Copyright © 2015 Elsevier Ltd. All rights reserved.

Whose idea was that? Source monitoring for idea ownership following elaboration.

PubMed

Stark, Louisa-Jayne; Perfect, Timothy J

2007-10-01

Unconscious plagiarism (UP) occurs when an individual claims a previously experienced idea as their own. Previous studies have explored the cognitive precursors of such errors by manipulating the ways that ideas are thought about between initial idea exposure and later test. While imagining other's ideas does not increase rates of UP relative to control on either a recall-own or generate-new task, improving others' ideas substantially increases such errors in the recall-own task. This study explored the effects of elaboration on rates of UP when a source-monitoring test replaced the recall-own test. Plagiarism was again observed following idea improvement but not idea imagery even though participants engaged explicit source evaluation. Thus the probability of plagiarising another's idea appears linked to the generative nature of the idea processing performed.

Critical care at the end of life: balancing technology with compassion and agreeing when to stop.

PubMed

Montgomery, H; Grocott, M; Mythen, M

2017-12-01

Modern intensive care saves lives. However, the substantial related financial costs are, for many, married to substantial costs in terms of suffering. In the most sick, the experience of intensive care is commonly associated with the development of profound physical debility, which may last years after discharge. Likewise, the negative psychological impact commonly experienced by such patients during their care is now widely recognized, as is the persistence of psychological morbidity. Such issues become increasingly important as the population of the frail elderly increases, and the health and social care services face budgetary restriction. Efforts must be made to humanize intensive care as much as possible. Meanwhile, an open conversation must be held between those within the medical professions, and between such healthcare workers and the public in general, regarding the balancing of the positive and negative impacts of intensive care. Such conversations should extend to individual patients and their families when considering what care is genuinely in their best interests. © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

School start times and teenage driver motor vehicle crashes.

DOT National Transportation Integrated Search

2015-12-01

There is substantial evidence that lack of sleep is a significant factor in motor vehicle crashes experienced by teenage drivers. This report examines the hypothesis that a later high school start time may reduce crash rates by reducing the interfere...

13 CFR 300.1 - Introduction and mission.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Investments in infrastructure development, capacity building and business development in order to attract private capital investments and higher-skill, higher-wage jobs to Regions experiencing substantial and... installations, changing trade patterns and the depletion of natural resources. EDA Investments generally take...

Weapon Carrying Among Victims of Bullying.

PubMed

Pham, Tammy B; Schapiro, Lana E; John, Majnu; Adesman, Andrew

2017-12-01

To examine, in a large, nationally representative sample of high school students, the association between bullying victimization and carrying weapons to school and to determine to what extent past experience of 1, 2, or 3 additional indicators of peer aggression increases the likelihood of weapon carrying by victims of bullying (VoBs). National data from the 2015 Youth Risk Behavior Survey were analyzed for grades 9 to 12 ( N = 15 624). VoB groups were determined by self-report of being bullied at school and additional adverse experiences: fighting at school, being threatened or injured at school, and skipping school out of fear for one's safety. Weapon carrying was measured by a dichotomized (ie, ≥1 vs 0) report of carrying a gun, knife, or club on school property. VoB groups were compared with nonvictims with respect to weapon carrying by logistic regression adjusting for sex, grade, and race/ethnicity. When surveyed, 20.2% of students reported being a VoB in the past year, and 4.1% reported carrying a weapon to school in the past month. VoBs experiencing 1, 2, or 3 additional risk factors were successively more likely to carry weapons to school. The subset of VoBs who experienced all 3 additional adverse experiences were more likely to carry weapons to school compared with nonvictims (46.4% vs 2.5%, P < .001). Pediatricians should recognize that VoBs, especially those who have experienced 1 or more indicators of peer aggression in conjunction, are at substantially increased risk of weapon carrying. Copyright © 2017 by the American Academy of Pediatrics.

CT triage for lung malignancy: coronal multiplanar reformation versus images in three orthogonal planes.

PubMed

Kusk, Martin Weber; Karstoft, Jens; Mussmann, Bo Redder

2015-11-01

Generation of multiplanar reformation (MPR) images has become automatic on most modern computed tomography (CT) scanners, potentially increasing the workload of the reporting radiologists. It is not always clear if this increases diagnostic performance in all clinical tasks. To assess detection performance using only coronal multiplanar reformations (MPR) when triaging patients for lung malignancies with CT compared to images in three orthogonal planes, and to evaluate performance comparison of novice and experienced readers. Retrospective study of 63 patients with suspicion of lung cancer, scanned on 64-slice multidetector computed tomography (MDCT) with images reconstructed in three planes. Coronal images were presented to four readers, two novice and two experienced. Readers decided whether the patients were suspicious for malignant disease, and indicated their confidence on a five-point scale. Sensitivity and specificity on per-patient basis was calculated with regards to a reference standard of histological diagnosis, and compared with the original report using McNemar's test. Receiver operating characteristic (ROC) curves were plotted to compare the performance of the four readers, using the area under the curve (AUC) as figure of merit. No statistically significant difference of sensitivity and specificity was found for any of the readers when compared to the original reports. ROC analysis yielded AUCs in the range of 0.92-0.93 for all readers with no significant difference. Inter-rater agreement was substantial (kappa = 0.72). Sensitivity and specificity were comparable to diagnosis using images in three planes. No significant difference was found between experienced and novice readers. © The Foundation Acta Radiologica 2014.

Impairment Severity and Evaluative and Experienced Well-being Among Older Adults: Assessing the Role of Daily Activities.

PubMed

Freedman, Vicki A; Carr, Deborah; Cornman, Jennifer C; Lucas, Richard E

2017-03-01

Physical impairments affect a substantial number of older adults in the United States, with rates increasing with advancing age. Impairment is linked with compromised well-being, although the reasons are not fully understood. We explore the extent to which linkages between impairment severity and well-being are accounted for by older adults' daily activities. We speculate that activities may influence global appraisals of well-being by offering the opportunity to fulfill productive and social roles and may influence daily emotions by shaping the context (places, people) in which life occurs. We examine the effects of impairment severity on life satisfaction and four diary-based experienced well-being measures (happiness, frustration, worry, and sadness). Data are from the Disability and Use of Time supplement to the Panel Study of Income Dynamics ( n = 1,606), a national sample of adults ages 60 years and older in the United States. We estimate nested regression models, taking into account within-person correlations for experienced well-being. Impairment severity is associated with poorer assessments of life satisfaction and all four dimensions of experienced well-being. Activity measures, which encompass eight productive (e.g., household chores) and three leisure (e.g., socializing) activities, account for 10% of the association between impairment and life satisfaction, and virtually none of the association between impairment and experienced well-being. However, psychosocial factors including higher neuroticism, lower self-efficacy, and poorer quality social relationships account for a sizeable share of the associations. Role-fulfilling aspects of activities appear to be more central than contextual aspects of activities to the impairment-well-being relationship. However, potentially modifiable psychosocial factors account for a much greater share of this relationship. Further research is needed on whether interventions targeting these psychosocial factors might bolster emotional well-being for older adults experiencing impairments.

Effect of Examiner Experience and Technique on the Alternate Cover Test

PubMed Central

Anderson, Heather A.; Manny, Ruth E.; Cotter, Susan A.; Mitchell, G. Lynn; Irani, Jasmine A.

2013-01-01

Purpose To compare the repeatability of the alternate cover test between experienced and inexperienced examiners and the effects of dissociation time and examiner bias. Methods Two sites each had an experienced examiner train 10 subjects (inexperienced examiners) to perform short and long dissociation time alternate cover test protocols at near. Each site conducted testing sessions with an examiner triad (experienced examiner and two inexperienced examiners) who were masked to each other’s results. Each triad performed the alternate cover test on 24 patients using both dissociation protocols. In an attempt to introduce bias, each of the paired inexperienced examiners was given a different graph of phoria distribution for the general population. Analysis techniques that adjust for correlations introduced when multiple measurements are obtained on the same patient were used to investigate the effect of examiner and dissociation time on each outcome. Results The range of measured deviations spanned 27.5 prism diopters (Δ) base-in to 17.5Δ base-out. The absolute mean difference between experienced and inexperienced examiners was 2.28 ± 2.4Δ and at least 60% of differences were ≤2Δ. Larger deviations were measured with the long dissociation protocol for both experienced and inexperienced examiners (mean difference range = 1.17 to 2.14Δ, p < 0.0001). The percentage of measured small deviations (2Δ base-out to 2Δ base-in) did not differ between inexperienced examiners biased with the narrow vs. wide theoretical distributions (p = 0.41). The magnitude and direction of the deviation had no effect on the size of the differences obtained with different examiners or dissociation times. Conclusions Although inexperienced examiners differed significantly from experienced examiners, most differences were <2Δ suggesting good reliability of inexperienced examiners’ measurements. Examiner bias did not have a substantial effect on inexperienced examiner measurements; however, increased dissociation resulted in larger measured deviations for all examiners. PMID:20125058

European Higher Education and the Process of Change

ERIC Educational Resources Information Center

Ríos, Cristina

2011-01-01

European higher education has experienced substantial changes as a result of the ongoing implementation of the "Bologna Process." Twenty nine (29) European countries signed the "Bologna Declaration" in 1999 committing themselves to transform, through cooperation, an archaic and separated assortment of higher education…

Stress Responses among Divorcing Men and Women

ERIC Educational Resources Information Center

Chiriboga, David A.; Cutler, Loraine

1977-01-01

Explores behavioral and emotional responses during the divorce process. Men and women (N=252) were interviewed about traumas and advantages associated with stages of divorce already experienced. Results only partially substantiate finding by Goode that final separation is perceived as most traumatic. (Author)

Optimising the performance of an outpatient setting.

PubMed

Sendi, Pedram; Al, Maiwenn J; Battegay, Manuel; Al Maiwenn, J

2004-01-24

An outpatient setting typically includes experienced and novice resident physicians who are supervised by senior staff physicians. The performance of this kind of outpatient setting, for a given mix of experienced and novice resident physicians, is determined by the number of senior staff physicians available for supervision. The optimum mix of human resources may be determined using discrete-event simulation. An outpatient setting represents a system where concurrency and resource sharing are important. These concepts can be modelled by means of timed Coloured Petri Nets (CPN), which is a discrete-event simulation formalism. We determined the optimum mix of resources (i.e. the number of senior staff physicians needed for a given number of experienced and novice resident physicians) to guarantee efficient overall system performance. In an outpatient setting with 10 resident physicians, two staff physicians are required to guarantee a minimum level of system performance (42-52 patients are seen per 5-hour period). However, with 3 senior staff physicians system performance can be improved substantially (49-56 patients per 5-hour period). An additional fourth staff physician does not substantially enhance system performance (50-57 patients per 5-hour period). Coloured Petri Nets provide a flexible environment in which to simulate an outpatient setting and assess the impact of any staffing changes on overall system performance, to promote informed resource allocation decisions.

Should we fear "flu fear" itself? Effects of H1N1 influenza fear on ED use.

PubMed

McDonnell, William M; Nelson, Douglas S; Schunk, Jeff E

2012-02-01

Surges in patient volumes compromise emergency departments' (EDs') ability to deliver care, as shown by the recent H1N1 influenza (flu) epidemic. Media reports are important in informing the public about health threats, but the effects of media-induced anxiety on ED volumes are unclear. The aim of this study is to examine the effect of widespread public concern about flu on ED use. We reviewed ED data from an integrated health system operating 18 hospital EDs. We compared ED visits during three 1-week periods: (a) a period of heightened public concern regarding flu before the disease was present ("Fear Week"), (b) a subsequent period of active disease ("Flu Week"), and (c) a week before widespread concern ("Control Week"). Fear Week was identified from an analysis of statewide Google electronic searches for "swine flu" and from media announcements about flu. Flu Week was identified from statewide epidemiological data. Data were reviewed from 22 608 visits during the study periods. Fear Week (n = 7712) and Flu Week (n = 7687) were compared to Control Week (n = 7209). Fear Week showed a 7.0% increase in visits (95% confidence interval, 6-8). Pediatric visits increased by 19.7%, whereas adult visits increased by 1%. Flu Week showed an increase over Control Week of 6.6% (95% confidence interval, 6-7). Pediatric visits increased by 10.6%, whereas adult visits increased by 4.8%. At a time of heightened public concern regarding flu but little disease prevalence, EDs experienced substantial increases in patient volumes. These increases were significant and comparable to the increases experienced during the subsequent epidemic of actual disease. Copyright © 2012 Elsevier Inc. All rights reserved.

Extent and variations in mobile phone use among drivers of heavy vehicles in Denmark.

PubMed

Troglauer, Thomas; Hels, Tove; Christens, Peter Falck

2006-01-01

A substantial body of research has shown that use of mobile phones while driving can impair driving performance and increase the risk of being involved in accidents. Similarly, mobile phone use seems to be an increasing activity thus representing a relevant traffic safety issue. This paper investigates the extent and variations in mobile phone use among drivers of heavy vehicles in Denmark. The data was collected through written questionnaires and had a response rate of 58%. It was found that more than 99% of the drivers used mobile phones while driving. Despite a prohibition of hand-held mobile phone use while driving 31% of the drivers reported to do so. Analysis of the variations in usage found a positive significant relationship between driving hours and phone use. A negative linear effect was found between age and phone use. Similarly, a positive significant association was found between the number of stops and the amount of phone use. 0.5% reported that their use of mobile phones had contributed to an accident, while 6% had experienced their mobile phone use causing a dangerous situation. However, 66% reported experiencing dangerous situations because of others road users' mobile phone use. Various implications of the findings are discussed particularly in relation to the drivers with high exposure.

Working Memory and Impulsivity Predict Marijuana-Related Problems Among Frequent Users

PubMed Central

Day, Anne M.; Metrik, Jane; Spillane, Nichea S.; Kahler, Christopher W.

2012-01-01

Background Although marijuana is the most commonly used illicit substance in the US, only a small portion of users go on to develop dependence, suggesting that there are substantial individual differences in vulnerability to marijuana-related problems among users. Deficits in working memory and high trait impulsivity are two factors that may place marijuana users at increased risk for experiencing related problems. Methods Using baseline data from an experimental study that recruited 104 frequent marijuana users (M=71.86% of prior 60 days, SD=22%), we examined the associations of working memory and trait impulsivity with marijuana-related problems. Results Lower working memory, as measured by Trail Making Test B, but not short-term memory capacity, predicted more marijuana-related problems. Higher trait impulsivity scores were independently associated with greater number of problems. Conclusions Results suggest that marijuana users with reduced executive cognitive ability are more susceptible to developing problems related to their use. Trait impulsivity and executive working memory appear to be independent risk factors for experiencing marijuana-related problems. PMID:23312340

The case for a southeastern Australian Dust Bowl, 1895-1945

NASA Astrophysics Data System (ADS)

Cattle, Stephen R.

2016-06-01

Australia has an anecdotal history of severe wind erosion and dust storm activity, but there has been no lasting public perception of periods of extreme dust storm activity in this country, such as that developed in the USA following the Dust Bowl of the 1930s. Newspaper accounts of droughts and dust storms in southeastern (SE) Australia between 1895 and 1945 suggest that, at various times, the scale of these events was comparable to those experienced in the USA Dust Bowl. During this 50-year period, average annual rainfall values in this region were substantially below long-term averages, air temperatures were distinctly warmer, marginal lands were actively cropped and grazed, and rabbits were a burgeoning grazing pest. From the beginning of the Federation Drought of 1895-1902, dust storm activity increased markedly, with the downwind coastal cities of Sydney and Melbourne experiencing dust hazes, dust storms and falls of red rain relatively regularly. Between 1935 and 1945, Sydney and Melbourne received ten and nine long-distance dust events, respectively, with the years of 1938 and 1944/45 being the most intensely dusty. Entire topsoil horizons were blown away, sand drift was extreme, and crops and sheep flocks were destroyed. Although these periods of extreme dust storm activity were not as sustained as those experienced in the USA in the mid-1930s, there is a strong case to support the contention that SE Australia experienced its own extended, somewhat episodic version of a Dust Bowl, with a similar combination of causal factors and landscape effects.

Southern pulpwood harvesting productivity and cost changes between 1979 and 1987.

Treesearch

Douglas R. Carter; Frederick W. Cubbage; Pamela J. Jakes

1994-01-01

The Southern U.S. pulpwood harvesting industry experienced substantial changes in productivity and logging costs from 1979 to 1987. This research measures physical and economic changes in southern timber harvesting and the degree of industry shifting between different levels of harvesting mechanization.

What Is School Enterprise?

ERIC Educational Resources Information Center

Brown, Daniel J.

1995-01-01

A survey of administrators and teachers in 20 British Columbia school districts that had experienced substantial reductions in public funding examined efforts to raise additional funds from private sources. Activities included casinos (bingo), requests for donations, sales of goods to the community, grant writing, and entrepreneurial efforts.…

Biblioklepts.

ERIC Educational Resources Information Center

Reed, Christopher

1997-01-01

The Harvard University (Massachusetts) open-stack libraries have experienced substantial losses of rare books and important manuscripts due to theft and vandalism. Some of the thieves have been found and prosecuted, among them several notorious or even respected individuals with long histories of book theft. Until recently, Harvard did not admit…

The disproportionate growth of office-based atherectomy.

PubMed

Mukherjee, Dipankar; Hashemi, Homayoun; Contos, Brian

2017-02-01

The purpose of this study was to evaluate the trends in procedure volume, clinical sites of care, and Medicare expenditure for peripheral vascular interventions (PVIs) for lower extremity occlusive disease since the Centers for Medicare and Medicaid Services instituted reimbursement policy changes that broadened payment for procedures performed in physician-owned office-based laboratories (OBLs). We analyzed fee-for-service Medicare claims data from 2011 to 2014 to obtain the frequency of use of PVI by type, care setting, and physician specialty. We also assessed changes in the total Medicare cost for PVI by setting. There was a 60% increase in atherectomy cases among Medicare beneficiaries between 2011 and 2014. During the same period, OBLs experienced a 298% increase in atherectomy volume vs a 27% increase in hospital outpatient settings and an 11% decrease for inpatient hospital settings. In 2014, OBLs were the most common setting for atherectomy. Nonatherectomy PVIs grew more modestly at just 3% but also experienced site of care shifts. Vascular surgeons and cardiologists accounted for the majority of office-based PVIs in 2014. Total Medicare costs for PVIs increased 18% from 2011 to 2014. Hospital inpatient costs declined 1%, whereas costs for hospital outpatient PVIs increased by 41% and physician office costs increased by 258%. The migration of revascularization procedures for lower extremity peripheral arterial occlusive disease continues from the inpatient to the outpatient setting and especially to OBLs. Increased use of atherectomy in all segments of the lower extremity arterial system has been observed, particularly in OBLs, without substantial evidence in the literature of increased efficacy compared with standard angioplasty with or without stenting. Generous Medicare reimbursement for in-office atherectomy procedures is likely contributing to the volume shifts observed. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

Substantial disease exacerbation in a patient with relapsing-remitting multiple sclerosis after withdrawal from siponimod.

PubMed

Litwin, Tomasz; Smoliński, Łukasz; Członkowka, Anna

Among patients with multiple sclerosis, discontinuing highly effective disease-modifying treatments can potentially lead to severe disease recurrence, especially cessation of natalizumab and fingolimod. Similar to fingolimod, siponimod is a sphingosine-1-phosphate receptor modulator that inhibits the egress of a lymphocyte subpopulation from lymph nodes. In the present case report, we describe a patient with MS who experienced substantial disease exacerbation after withdrawal from siponimod. Copyright © 2017 Polish Neurological Society. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

Phenological mismatch with abiotic conditions implications for flowering in Arctic plants.

PubMed

Wheeler, Helen C; Høye, Toke T; Schmidt, Niels Martin; Svenning, Jens-Christian; Forchhammer, Mads C

2015-03-01

Although many studies have examined the phenological mismatches between interacting organisms, few have addressed the potential for mismatches between phenology and seasonal weather conditions. In the Arctic, rapid phenological changes in many taxa are occurring in association with earlier snowmelt. The timing of snowmelt is jointly affected by the size of the late winter snowpack and the temperature during the spring thaw. Increased winter snowpack results in delayed snowmelt, whereas higher air temperatures and faster snowmelt advance the timing of snowmelt. Where interannual variation in snowpack is substantial, changes in the timing of snowmelt can be largely uncoupled from changes in air temperature. Using detailed, long-term data on the flowering phenology of four arctic plant species from Zackenberg, Greenland, we investigate whether there is a phenological component to the temperature conditions experienced prior to and during flowering. In particular, we assess the role of timing of flowering in determining pre-flowering exposure to freezing temperatures and to the temperatures-experienced prior to flowering. We then examine the implications of flowering phenology for flower abundance. Earlier snowmelt resulted in greater exposure to freezing conditions, suggesting an increased potential for a mismatch between the timing of flowering and seasonal weather conditions and an increased potential for negative consequences, such as freezing 'damage. We also found a parabolic relationship between the timing of flowering and the temperature experienced during flowering after taking interannual temperature effects into account. If timing of flowering advances to a cooler period of the growing season, this may moderate the effects of a general warming trend across years. Flower abundance was quadratically associated with the timing of flowering, such that both early and late flowering led to lower flower abundance than did intermediate flowering. Our results indicate that shifting the timing of flowering affects the temperature experienced during flower development and flowering beyond that imposed by interannual variations in climate. We also found that phenological timing may affect flower abundance, and hence, fitness. These findings suggest that plant population responses to future climate change will be shaped not only by extrinsic climate forcing, but also by species' phenological responses.

Unprecedented climate events: Historical changes, aspirational targets, and national commitments

PubMed Central

Diffenbaugh, Noah S.; Singh, Deepti; Mankin, Justin S.

2018-01-01

The United Nations Paris Agreement creates a specific need to compare consequences of cumulative emissions for pledged national commitments and aspirational targets of 1.5° to 2°C global warming. We find that humans have already increased the probability of historically unprecedented hot, warm, wet, and dry extremes, including over 50 to 90% of North America, Europe, and East Asia. Emissions consistent with national commitments are likely to cause substantial and widespread additional increases, including more than fivefold for warmest night over ~50% of Europe and >25% of East Asia and more than threefold for wettest days over >35% of North America, Europe, and East Asia. In contrast, meeting aspirational targets to keep global warming below 2°C reduces the area experiencing more than threefold increases to <10% of most regions studied. However, large areas—including >90% of North America, Europe, East Asia, and much of the tropics—still exhibit sizable increases in the probability of record-setting hot, wet, and/or dry events. PMID:29457133

Unprecedented climate events: Historical changes, aspirational targets, and national commitments.

PubMed

Diffenbaugh, Noah S; Singh, Deepti; Mankin, Justin S

2018-02-01

The United Nations Paris Agreement creates a specific need to compare consequences of cumulative emissions for pledged national commitments and aspirational targets of 1.5° to 2°C global warming. We find that humans have already increased the probability of historically unprecedented hot, warm, wet, and dry extremes, including over 50 to 90% of North America, Europe, and East Asia. Emissions consistent with national commitments are likely to cause substantial and widespread additional increases, including more than fivefold for warmest night over ~50% of Europe and >25% of East Asia and more than threefold for wettest days over >35% of North America, Europe, and East Asia. In contrast, meeting aspirational targets to keep global warming below 2°C reduces the area experiencing more than threefold increases to <10% of most regions studied. However, large areas-including >90% of North America, Europe, East Asia, and much of the tropics-still exhibit sizable increases in the probability of record-setting hot, wet, and/or dry events.

Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age

PubMed Central

Ruby, J Graham; Smith, Megan

2018-01-01

The longest-lived rodent, the naked mole-rat (Heterocephalus glaber), has a reported maximum lifespan of >30 years and exhibits delayed and/or attenuated age-associated physiological declines. We questioned whether these mouse-sized, eusocial rodents conform to Gompertzian mortality laws by experiencing an exponentially increasing risk of death as they get older. We compiled and analyzed a large compendium of historical naked mole-rat lifespan data with >3000 data points. Kaplan-Meier analyses revealed a substantial portion of the population to have survived at 30 years of age. Moreover, unlike all other mammals studied to date, and regardless of sex or breeding-status, the age-specific hazard of mortality did not increase with age, even at ages 25-fold past their time to reproductive maturity. This absence of hazard increase with age, in defiance of Gompertz’s law, uniquely identifies the naked mole-rat as a non-aging mammal, confirming its status as an exceptional model for biogerontology. PMID:29364116

A survey of Bolivian lumber drying operations

Treesearch

Omar A. Espinoza; Brian H. Bond; Philip Araman

2007-01-01

The Bolivian secondary forest products industry has experienced substantial growth during the last 10 years. Particularly, important investment has taken place in lumber drying capacity. Unfortunately, little information is available regarding lumber drying technology and practices used, which is essential for the formulation of improvement strategies. The Bolivian...

Managing Large-Scale Online Graduate Programs

ERIC Educational Resources Information Center

Singleton, Jacques; Bowser, Audrey; Hux, Annette; Neal, Gwendolyn

2013-01-01

As with most states, Arkansas is experiencing substantial growth in the delivery of academic programs and courses by distance learning provided by institutions of higher education. At Arkansas State University faculty have adhered to the need of students and developed a completely online certification and master's program in Educational…

Experiencing Wrongful and Unlawful Conviction

ERIC Educational Resources Information Center

Wildeman, Jennifer; Costelloe, Michael; Schehr, Robert

2011-01-01

This study examines how those wrongfully convicted and punished experience life after exoneration. Using data from intensive individual, in-person interviews with 55 exonerees, we measure both the short- and long-term psychological effects associated with wrongful conviction. The results of this research demonstrate that a substantial portion of…

The land value impacts of wetland restoration.

PubMed

Kaza, Nikhil; BenDor, Todd K

2013-09-30

U.S. regulations require offsets for aquatic ecosystems damaged during land development, often through restoration of alternative resources. What effect does large-scale wetland and stream restoration have on surrounding land values? Restoration effects on real estate values have substantial implications for protecting resources, increasing tax base, and improving environmental policies. Our analysis focuses on the three-county Raleigh-Durham-Chapel Hill, North Carolina region, which has experienced rapid development and extensive aquatic ecological restoration (through the state's Ecosystem Enhancement Program [EEP]). Since restoration sites are not randomly distributed across space, we used a genetic algorithm to match parcels near restoration sites with comparable control parcels. Similar to propensity score analysis, this technique facilitates statistical comparison and isolates the effects of restoration sites on surrounding real estate values. Compared to parcels not proximate to any aquatic resources, we find that, 1) natural aquatic systems steadily and significantly increase parcel values up to 0.75 mi away, and 2) parcels <0.5 mi from EEP restoration sites have significantly lower sale prices, while 3) parcels >0.5 mi from EEP sites gain substantial amenity value. When we control for intervening water bodies (e.g. un-restored streams and wetlands), we find a similar inflection point whereby parcels <0.5 mi from EEP sites exhibit lower values, and sites 0.5-0.75 mi away exhibit increased values. Our work points to the need for higher public visibility of aquatic ecosystem restoration programs and increased public information about their value. Copyright © 2013 Elsevier Ltd. All rights reserved.

Hearing loss in children with very low birth weight: current review of epidemiology and pathophysiology

PubMed Central

Cristobal, R; Oghalai, J S

2013-01-01

An association between birth weight <1500 g (very low birth weight (VLBW)) and hearing loss has been long recognised. As universal hearing screening programmes have become widely implemented and the survival rate of VLBW babies in modern intensive care units has increased, we have gained a substantially better understanding of the nature of this problem. However, many gaps in our knowledge base exist. This review describes recent data on hearing loss in the VLBW population and explains the current level of understanding about the physiological basis underlying the auditory deficits in these patients. Although VLBW alone may not have a severe impact on hearing, it is commonly associated with multiple other risk factors that can alter hearing in a synergistic fashion. Therefore, the risk of hearing loss is substantially higher than in the general newborn population. Also, it is important to perform a more comprehensive audiometric evaluation than standard otoacoustic emission screening for infants who are in the neonatal intensive care unit in order not to miss hearing loss due to retrocochlear pathology. Furthermore, children with VLBW are also at increased risk of experiencing progressive or delayed-onset hearing loss, and thus should continue to have serial hearing evaluations after discharge from the neonatal intensive care unit. PMID:18941031

Cognitive Abilities of Children With Neurological and Liver Forms of Wilson Disease.

PubMed

Favre, Emilie; Lion-François, Laurence; Canton, Marie; Vanlemmens, Claire; Bonneton, Marjorie; Bouillet, Lise; Brunet, Anne-Sophie; Lachaux, Alain

2017-03-01

Cognitive impairment in adult patients experiencing Wilson disease is now more clearly described, even in liver forms of the disease. Although this condition can appear during childhood, the cognitive abilities of children have not yet been reported in a substantial case series. This retrospective study included 21 children with Wilson disease who had undergone general cognitive assessment. The results argue in favor of a poor working memory capacity in the liver form of the disease, and more extensive cognitive impairments in its neurological form. Extensive neuropsychological investigations on all children experiencing Wilson disease are thus required.

Long-term trends in supply and sustainability of the health workforce in remote Aboriginal communities in the Northern Territory of Australia.

PubMed

Zhao, Yuejen; Russell, Deborah J; Guthridge, Steven; Ramjan, Mark; Jones, Michael P; Humphreys, John S; Carey, Timothy A; Wakerman, John

2017-12-19

International evidence suggests that a key to improving health and attaining more equitable health outcomes for disadvantaged populations is a health system with a strong primary care sector. Longstanding problems with health workforce supply and turnover in remote Aboriginal communities in the Northern Territory (NT), Australia, jeopardise primary care delivery and the effort to overcome the substantial gaps in health outcomes for this population. This research describes temporal changes in workforce supply in government-operated clinics in remote NT communities through a period in which there has been a substantial increase in health funding. Descriptive and Markov-switching dynamic regression analysis of NT Government Department of Health payroll and financial data for the resident health workforce in 54 remote clinics, 2004-2015. The workforce included registered Remote Area Nurses and Midwives (nurses), Aboriginal Health Practitioners (AHPs) and staff in administrative and logistic roles. total number of unique employees per year; average annual headcounts; average full-time equivalent (FTE) positions; agency employed nurse FTE estimates; high and low supply state estimates. Overall increases in workforce supply occurred between 2004 and 2015, especially for administrative and logistic positions. Supply of nurses and AHPs increased from an average 2.6 to 3.2 FTE per clinic, although supply of AHPs has declined since 2010. Each year almost twice as many individual NT government-employed nurses or AHPs are required for each FTE position. Following funding increases, some clinics doubled their nursing and AHP workforce and achieved relative stability in supply. However, most clinics increased staffing to a much smaller extent or not at all, typically experiencing a "fading" of supply following an initial increase associated with greater funding, and frequently cycling periods of higher and lower staffing levels. Overall increases in workforce supply in remote NT communities between 2004 and 2015 have been affected by continuing very high turnover of nurses and AHPs, and compounded by recent declines in AHP supply. Despite substantial increases in resourcing, an imperative remains to implement more robust health service models which better support the supply and retention of resident health staff.

Children’s experiences of family disruption in Sweden: Differentials by parent education over three decades

PubMed Central

Kennedy, Sheela; Thomson, Elizabeth

2010-01-01

This paper examines the living arrangements of Swedish children from 1970 through 1999 using the Level of Living Survey. Sweden, with low levels of economic inequality and a generous welfare state, provides an important context for studying socioeconomic differentials in family structure. We find that, although differences by parent education in non-marital childbearing are substantial and persistent, cohabiting childbearing is common even among highly educated Swedish parents. Educational differences in family instability were small during the 1970s, but increased over time as a result of rising union disruption among less-educated parents (secondary graduates or less). Children in more advantaged families experienced substantially less change in family structure and instability over the study period. Although cohabiting parents were more likely to separate than parents married at the child’s birth, differences were greater for the less-educated. Data limitations precluded investigating these differences across time. We conclude that educational differences in children’s living arrangements in Sweden have grown, but remain small in international comparisons. PMID:21113397

Detecting warning signs of trouble within population fluctuations: using capture-recapture modeling to uncover changes in population dynamics leading to declines

USGS Publications Warehouse

Spendelow, J.A.; Nichols, J.D.; Kendall, W.L.; Hines, J.E.; Hatfield, J.S.; Nisbet, I.C.T.

2004-01-01

An intensive mark-recapture/resighting program has been carried out on the Roseate Terns nesting at Falkner Island, Connecticut, since the late 1980s as part of a regional study of the metapopulation dynamics and ecology of the endangered Northwest Atlantic breeding population of this species. Substantial losses of tern eggs and chicks to predation at this colony site began in 1996 when at least five Black-crowned Night-Herons started nocturnal raids. This depredation has been a major factor in the reduction of productivity from an average of about 1.0 chicks/pair for the 10 years before night-heron predation began to as low as about 0.2 chicks/pair in 2002. Recent capture-recapture modelling analyses have detected other important impacts on the population dynamics of the Roseate Terns at this site including a reduction by about half in the 'development-of-residency' rates of first-time breeders, and a substantial decline in the local 'survival-and-fidelity' rates of experienced breeders believed due mostly to increased immigration rates to other colony sites.

Caregiver burden, family accommodation, health, and well-being in relatives of individuals with hoarding disorder.

PubMed

Drury, Helena; Ajmi, Sana; Fernández de la Cruz, Lorena; Nordsletten, Ashley E; Mataix-Cols, David

2014-04-01

Hoarding Disorder (HD), a new diagnostic entity in DSM-5, is associated with substantial functional impairment and family frustration but data from well-characterized samples is lacking. Participants were 37 individuals meeting DSM-5 criteria for HD, 55 relatives of individuals meeting criteria for HD, and comparison groups of 51 self-identified collectors and 25 relatives of collectors. All participants completed a clinician-administered diagnostic interview for HD and an online battery of standardized measures of health, well-being, and impairment. Substantial functional impairment was found for both HD individuals and their relatives. HD relatives reported significantly greater carer burden and accommodation of hoarding behaviors than relatives of collectors. Perceived level of squalor, co-habiting with, and increasing age of the HD individual were significant predictors of carer burden and functional impairment in the relatives. The use of self-identified HD individuals may have produced a bias towards participants with relatively good insight. Subjective biases in self-reported symptoms cannot be ruled out, although the use of informant-report data provided some independent validation. HD is associated with substantial functional impairment for both sufferers and their relatives. The level of carer burden experienced by HD relatives was comparable to or greater than that reported in the literature by relatives of individuals with dementia. The findings indicate that relatives of individuals with HD may benefit from increased support and suggest that it may be beneficial to involve family members in the treatment of HD. Copyright © 2014 Elsevier B.V. All rights reserved.

Clinical Reasoning in the Assessment and Intervention Planning for Major Depression

ERIC Educational Resources Information Center

Hanchon, Timothy A.; Phelps, Kenneth W.; Fernald, Lori N.; Splett, Joni W.

2017-01-01

Accurate assessment and effective treatment of mood disorders, particularly depression, is critically important for the millions of youth who are experiencing such symptomatology and who are at risk for a multitude of deleterious outcomes. Although the extant empirical literature provides substantial guidance for the assessment and treatment of…

Middle School Science: Working in a Confused Context.

ERIC Educational Resources Information Center

Berns, Barbara Brauner; Swanson, Judy

This paper presents the stories of two urban middle school science teachers, both identified as leaders in their districts. Both bring substantial expertise to science education, though neither has experienced optimal conditions for flourishing as teacher leaders. One teacher has strong content knowledge and a deep understanding of standards. The…

Efficient Use of Clickers: A Mixed-Method Inquiry with University Teachers

ERIC Educational Resources Information Center

Cheung, George; Wan, Kelvin; Chan, Kevin

2018-01-01

With the advancement of information technology and policies encouraging interactivities in teaching and learning, the use of students' response system (SRS), commonly known as clickers, has experienced substantial growth in recent years. The reported effectiveness of SRS has varied. Based on the framework of technological-pedagogical-content…

The Impact of Virtual Reality Programs in Career and Technical Education

ERIC Educational Resources Information Center

Catterson, Anna J.

2013-01-01

Instructional technology has evolved from blackboards with chalk to in some cases three-dimensional virtual reality environments in which students are interacting and engaging with other students worldwide. The use of this new instructional methodology, known as "virtual reality," has experienced substantial growth in higher education…

Habitat availability is a more plausible explanation than insecticide acute toxicity for U.S. grassland bird species declines

USDA-ARS?s Scientific Manuscript database

Grassland bird species have experienced substantial declines in North America. These declines have been largely attributed to habitat loss and degradation, especially from agricultural practices and intensification (the habitat-availability hypothesis). A recent analysis of North American Breeding B...

Educational Expansion and Inequality in Taiwan and the Czech Republic

ERIC Educational Resources Information Center

Smith, Michael; Tsai, Shu-Ling; Mateju, Petr; Huang, Min-Hsiung

2016-01-01

This article presents a comparative analysis of educational inequality by family background and gender in Taiwan and the Czech Republic, which have both experienced substantial educational expansion in the last half-century under different educational systems. We highlight the specific institutional histories of both countries and examine the role…

Fact Sheet: Vulnerable Young Children

ERIC Educational Resources Information Center

Shaw, Evelyn, Comp.; Goode, Sue, Comp.

2008-01-01

This fact sheet provides data on infants, toddlers and young children who are experiencing high stress as a result of a number of risk factors specifically identified in the Individuals with Disabilities Education Improvement Act of 2004 (IDEA 2004), including substantiated abuse or neglect, foster care placement, homelessness, exposure to family…

Geographic Mobility of Manpower in the USSR.

ERIC Educational Resources Information Center

Kossov, V. V.; Tatevosoc, R. V.

1984-01-01

The Soviet Union is experiencing substantial reduction in the growth of the working-age population, accompanied by a shift in the distribution of population growth. The government is using various means to encourage workers to move to the sparsely populated developing regions and away from the large cities. (SK)

Elite Private Colleges See a Drop in Applications.

ERIC Educational Resources Information Center

Gose, Ben

1997-01-01

Applicants to highly selective private colleges are down substantially nationwide. Flagship public universities are experiencing a drop in minority applicants, particularly in Texas and California, where use of race as a factor in admissions has been under attack. It is suggested that parents of minority students perceive the institutions are not…

The Quality of Life in China

ERIC Educational Resources Information Center

Shu, Xiaoling; Zhu, Yifei

2009-01-01

The Asia Barometer Survey of 2,000 respondents reveals that substantial majorities of the Chinese people experience feelings of happiness, enjoyment, and accomplishment. In fact, the proportion experiencing these indicators of a high quality of life are larger in China than in some more prosperous countries. Favorable historical comparison,…

Geomorphic Response to Two Lowhead Dam Removals in a Mid-Sized Urban River System, Columbus, Ohio, USA: Export of Impounded Reservoir Sediments Results in Upstream Coarsening and Moderate Increases in Downstream Bathymetric Heterogeneity

NASA Astrophysics Data System (ADS)

Comes, E.; Jaeger, K. L.

2016-12-01

Lowhead dams have had a profound cumulative impact on rivers and streams. Their removal is an increasingly popular restoration method, however, geomorphic response remains poorly resolved. This study quantified geomorphic change following two lowhead dam removal in the Olentangy River and the downstream Scioto River, which flows through Columbus, Ohio. A paired control-treatment design compared change above and below a removed dam (treatment) to an existing dam (control) in each river system over a two and three-year period. Upstream treatment reaches included passive and active restoration via in-channel engineering. Channel change was quantified through repeat bathymetric surveys using an acoustic Doppler current profiles and near-surface riverbed substrate sampling at several time periods ( 2 surveys/year). Differencing of digital elevation models from each bathymetric survey quantified changes in erosion and deposition patterns and bathymetric heterogeneity. Results indicate upstream treatment reaches were net erosional with overall substrate coarsening that included D84 sand to gravel clast size shifts. The Olentangy River's downstream treatment reach experienced concurrent erosion and deposition within a given survey although net erosion dominated the first year of the three-year study period. The downstream treatment reach also experienced substantial grain size fluctuation between surveys with little overall change. Unanticipated engineering activities in the downstream treatment reach of the Scioto River confounded geomorphic change in this reach. Non-metric multidimensional scaling analysis indicates a moderate, but abrupt change towards overall increased heterogeneity in the first year following dam removal in the downstream reach with little overall change in the following two years. Active restoration activities in the upstream treatment reach resulted in abrupt, but slight shifts towards decreased bathymetric heterogeneity despite substantial riverbed regrading to create pool-riffle features. Repeat intra-annual surveys revealed that the river system experiences clear seasonal patterns of erosion and deposition with associated substrate coarsening and fining that would not be evident in typical dam removal studies that generally are limited to annual surveys.

The impact of adverse events on health care costs for older adults undergoing nonelective abdominal surgery.

PubMed

Bailey, Jonathan G; Davis, Philip J B; Levy, Adrian R; Molinari, Michele; Johnson, Paul M

2016-06-01

Postoperative complications have been identified as an important and potentially preventable cause of increased hospital costs. While older adults are at increased risk of experiencing complications and other adverse events, very little research has specifically examined how these events impact inpatient costs. We sought to examine the association between postoperative complications, hospital mortality and loss of independence and direct inpatient health care costs in patients 70 years or older who underwent nonelective abdominal surgery. We prospectively enrolled consecutive patients 70 years or older who underwent nonelective abdominal surgery between July 1, 2011, and Sept. 30, 2012. Detailed patient-level data were collected regarding demographics, diagnosis, treatment and outcomes. Patient-level resource tracking was used to calculate direct hospital costs (2012 $CDN). We examined the association between complications, hospital mortality and loss of independence cost using multiple linear regression. During the study period 212 patients underwent surgery. Overall, 51.9% of patients experienced a nonfatal complication (32.5% minor and 19.4% major), 6.6% died in hospital and 22.6% experienced a loss of independence. On multivariate analysis nonfatal complications (p < 0.001), hospital mortality (p = 0.021) and loss of independence at discharge (p < 0.001) were independently associated with health care costs. These adverse events respectively accounted for 30%, 4% and 10% of the total costs of hospital care. Adverse events were common after abdominal surgery in older adults and accounted for 44% of overall costs. This represents a substantial opportunity for better patient outcomes and cost savings with quality improvement strategies tailored to the needs of this high-risk surgical population.

Social adversities in first-time and repeat prisoners.

PubMed

Kjelsberg, Ellen; Friestad, Christine

2008-11-01

To explore possible systematic differences between prison inmates serving their first sentence and inmates having experienced previous incarcerations. It is hoped that a better knowledge of these issues will make us better equipped to meet the rehabilitation needs of our prisoners and decrease their risk of reoffending and reincarceration. In this cross-sectional study a randomly selected and nationally representative sample of 260 Norwegian prisoners, 100 serving their first sentence and 160 recidivists, was interviewed with special focus on childhood circumstances, education, work experience, and present social and economic situation. In addition their criminal records were collected from the National Crime Registry. In males multivariate analyses identified a number of variables independently and significantly associated with being a repeat offender. The odds for reincarceration increased significantly if the person fulfilled any one of the following criteria: having experienced the incarceration of a family member during childhood (OR = 3.6); having experienced childcare interventions during childhood (OR = 3.2); current drug abuse (OR = 2.6); current housing problems (OR = 2.3). In females only one strong correlation emerged: if the person had current drug problems the odds for being a recidivist increased substantially (OR = 10.9). While criminal reoffending and reincarceration seemed to be primarily associated with drug abuse in females, the childhood problems of male repeat offenders, compared with males serving their first sentence, indicate that these individuals' current multiple social and economic disadvantages were complex in origin and of long standing. Interventions aimed at preventing reoffending must take into account the gender differences demonstrated. ing at primary prevention, the negative effects associated with parental incarceration are crucial: how can one prevent the perpetuation of these problems from one generation to the next?

Progress and prospects of climate change impacts on hydrology in the arid region of northwest China.

PubMed

Chen, Yaning; Li, Zhi; Fan, Yuting; Wang, Huaijun; Deng, Haijun

2015-05-01

The arid region of Northwest China, located in the central Asia, responds sensitively to global climate change. Based on the newest research results, this paper analyzes the impacts of climate change on hydrology and the water cycle in the arid region of Northwest China. The analysis results show that: (1) In the northwest arid region, temperature and precipitation experienced "sharply" increasing in the past 50 years. The precipitation trend changed in 1987, and since then has been in a state of high volatility, during the 21st century, the increasing rate of precipitation was diminished. Temperature experienced a "sharply" increase in 1997; however, this sharp increasing trend has turned to an apparent hiatus since the 21st century. The dramatic rise in winter temperatures in the northwest arid region is an important reason for the rise in the average annual temperature, and substantial increases in extreme winter minimum temperature play an important role in the rising average winter temperature; (2) There was a significant turning point in the change of pan evaporation in the northwest arid area in 1993, i.e., in which a significant decline reversed to a significant upward trend. In the 21st century, the negative effects of global warming and increasing levels of evaporation on the ecology of the northwest arid region have been highlighted; (3) Glacier change has a significant impact on hydrology in the northwest arid area, and glacier inflection points have appeared in some rivers. The melting water supply of the Tarim River Basin possesses a large portion of water supplies (about 50%). In the future, the amount of surface water will probably remain at a high state of fluctuation. Copyright © 2015 Elsevier Inc. All rights reserved.

Impact of Survivorship-Based Research on Defining Clinical Care Guidelines

PubMed Central

Hudson, Melissa M.; Landier, Wendy; Ganz, Patricia A.

2011-01-01

The growing number of individuals living 5 or more years from cancer diagnosis underscores the importance of providing guidance about potential late treatment effects to clinicians caring for long-term cancer survivors. Late treatment effects are commonly experienced by cancer survivors, increase in prevalence with aging, produce substantial morbidity, and predispose to early mortality. Findings from survivorship research permit providers to anticipate health risks among predisposed survivors and facilitate their access to interventions to prevent, detect, or rehabilitate cancer-related morbidity. This manuscript reviews the impact that survivorship research has made in defining clinical care guidelines and the challenges that remain in developing and translating research findings into health screening recommendations that can optimize the quality and duration of survival after cancer. PMID:21980016

Characterization of Friction Joints Subjected to High Levels of Random Vibration

NASA Technical Reports Server (NTRS)

deSantos, Omar; MacNeal, Paul

2012-01-01

This paper describes the test program in detail including test sample description, test procedures, and vibration test results of multiple test samples. The material pairs used in the experiment were Aluminum-Aluminum, Aluminum- Dicronite coated Aluminum, and Aluminum-Plasmadize coated Aluminum. Levels of vibration for each set of twelve samples of each material pairing were gradually increased until all samples experienced substantial displacement. Data was collected on 1) acceleration in all three axes, 2) relative static displacement between vibration runs utilizing photogrammetry techniques, and 3) surface galling and contaminant generation. This data was used to estimate the values of static friction during random vibratory motion when "stick-slip" occurs and compare these to static friction coefficients measured before and after vibration testing.

Climate Variability and Impact at NASA's Marshal Space Flight Center

NASA Technical Reports Server (NTRS)

Smoot, James L.; Jedlovec, Gary; Williams, Brett

2013-01-01

Climate analysis for the Southeast U. S. has indicated that inland regions have experienced an average temperature increase of 2F since 1970. This trend is generally characterized by warmer winters with an indication of increased precipitation in the Fall season. Extended periods of limited rainfall in the Spring and Summer periods have had greater areal coverage and, at other times the number of precipitation events has been increasing. Climate model projections for the next 10-70 years indicate warmer temperatures for the Southeast U.S., particularly in the Spring and Summer, with some indication of more extremes in temperature and precipitation as shown in the table below. The realization of these types of regional climate changes in the form of extended heat waves and droughts and their subsequent stress on facilities, infrastructure, and workforce could have substantial impact on the activities and functions of NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This presentation will present the results of an examination of the 100 year temperature and precipitation record for MSFC. Local warming has cause an increase in daily maximum and minimum temperatures by nearly 3F, with a substantial increase in the number of maximum temperatures exceeding 90F and a decrease in the number of days with minimum temperatures below freezing. These trends have substantial impact of the number of heating / cooling degree days for the area. Yearly precipitation totals are inversely correlated with the change in mean temperature and the frequency of heavy rain events has remain consistent with the changes in yearly totals. An extended heat wave index was developed which shows an increase in frequency of heat waves over the last 35 years and a subsequent reduction in precipitation during the heat waves. This trend will contribute to more intense drought conditions over the northern Alabama region, increasing the potential of destructive wildfires in and around the Center. MSFC has begun using this climate change information to adapt short-term and long-term plans for Center operations.

Demographic amplification of climate change experienced by the contiguous United States population during the 20(th) century.

PubMed

Samson, Jason; Berteaux, Dominique; McGill, Brian J; Humphries, Murray M

2012-01-01

Better understanding of the changing relationship between human populations and climate is a global research priority. The 20(th) century in the contiguous United States offers a particularly well-documented example of human demographic expansion during a period of radical socioeconomic and environmental change. One would expect that as human society has been transformed by technology, we would become increasingly decoupled from climate and more dependent on social infrastructure. Here we use spatially-explicit models to evaluate climatic, socio-economic and biophysical correlates of demographic change in the contiguous United States between 1900 and 2000. Climate-correlated variation in population growth has caused the U.S. population to shift its realized climate niche from cool, seasonal climates to warm, aseasonal climates. As a result, the average annual temperature experienced by U.S. citizens between 1920 and 2000 has increased by more than 1.5°C and the temperature seasonality has decreased by 1.1°C during a century when climate change accounted for only a 0.24°C increase in average annual temperature and a 0.15°C decrease in temperature seasonality. Thus, despite advancing technology, climate-correlated demographics continue to be a major feature of contemporary U.S. society. Unfortunately, these demographic patterns are contributing to a substantial warming of the climate niche during a period of rapid environmental warming, making an already bad situation worse.

Demographic Amplification of Climate Change Experienced by the Contiguous United States Population during the 20th Century

PubMed Central

Samson, Jason; Berteaux, Dominique; McGill, Brian J.; Humphries, Murray M.

2012-01-01

Better understanding of the changing relationship between human populations and climate is a global research priority. The 20th century in the contiguous United States offers a particularly well-documented example of human demographic expansion during a period of radical socioeconomic and environmental change. One would expect that as human society has been transformed by technology, we would become increasingly decoupled from climate and more dependent on social infrastructure. Here we use spatially-explicit models to evaluate climatic, socio-economic and biophysical correlates of demographic change in the contiguous United States between 1900 and 2000. Climate-correlated variation in population growth has caused the U.S. population to shift its realized climate niche from cool, seasonal climates to warm, aseasonal climates. As a result, the average annual temperature experienced by U.S. citizens between 1920 and 2000 has increased by more than 1.5°C and the temperature seasonality has decreased by 1.1°C during a century when climate change accounted for only a 0.24°C increase in average annual temperature and a 0.15°C decrease in temperature seasonality. Thus, despite advancing technology, climate-correlated demographics continue to be a major feature of contemporary U.S. society. Unfortunately, these demographic patterns are contributing to a substantial warming of the climate niche during a period of rapid environmental warming, making an already bad situation worse. PMID:23115624

Attribution of the July–August 2013 heat event in Central and Eastern China to anthropogenic greenhouse gas emissions

DOE PAGES

Ma, Shuangmei; Zhou, Tianjun; Stone, Dáithí A.; ...

2017-05-19

In the midsummer of 2013, Central and Eastern China (CEC) was hit by an extraordinary heat event, with the region experiencing the warmest July-August on record. To explore how human-induced greenhouse gas emissions and natural internal variability contributed to this heat event, we compare observed July-August mean surface air temperature wit h that simulated by climate models. We find that both atmospheric natural variability and anthropogenic factors contributed to this heat event. This extreme warm midsummer was associated with a positive high-pressure anomaly that was closely related to the stochastic behavior of atmospheric circulation. Diagnosis of CMIP5 models and largemore » ensembles of two atmospheric models indicates that human influence has substantially increased the chance of warm mid-summers such as 2013 in CEC, although the exact estimated increase depends on the selection of climate models.« less

Solar on the Rise: How Cost Declines and Grid Integration Shape Solar's Growth Potential in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, Wesley J; Denholm, Paul L; Feldman, David J

During the past decade, solar power has experienced transformative price declines, enabling it to become a viable electricity source that is supplying 1% of U.S. and world electricity. Further cost reductions are expected to enable substantially greater solar deployment, and new Department of Energy cost targets for utility-scale photovoltaics (PV) and concentrating solar thermal power are $0.03/kW h and $0.05/kW h by 2030, respectively. However, cost reductions are no longer the only significant challenge for PV - addressing grid integration challenges and increasing grid flexibility are critical as the penetration of PV electricity on the grid increases. The development ofmore » low cost energy storage is particularly synergistic with low cost PV, as cost declines in each technology are expected to support greater market opportunities for the other.« less

Photonic Crystal Enhanced Fluorescence for Early Breast Cancer Biomarker Detection

PubMed Central

Cunningham, Brian T.; Zangar, Richard C.

2013-01-01

Photonic crystal surfaces offer a compelling platform for improving the sensitivity of surface-based fluorescent assays used in disease diagnostics. Through the complementary processes of photonic crystal enhanced excitation and enhanced extraction, a periodic dielectric-based nanostructured surface can simultaneously increase the electric field intensity experienced by surface-bound fluorophores and increase the collection efficiency of emitted fluorescent photons. Through the ability to inexpensively fabricate photonic crystal surfaces over substantial surface areas, they are amenable to single-use applications in biological sensing, such as disease biomarker detection in serum. In this review, we will describe the motivation for implementing high-sensitivity, multiplexed biomarker detection in the context of breast cancer diagnosis. We will summarize recent efforts to improve the detection limits of such assays though the use of photonic crystal surfaces. Reduction of detection limits is driven by low autofluorescent substrates for photonic crystal fabrication, and detection instruments that take advantage of their unique features. PMID:22736539

The effectiveness of coral reefs for coastal hazard risk reduction and adaptation

PubMed Central

Ferrario, Filippo; Beck, Michael W.; Storlazzi, Curt D.; Micheli, Fiorenza; Shepard, Christine C.; Airoldi, Laura

2014-01-01

The world’s coastal zones are experiencing rapid development and an increase in storms and flooding. These hazards put coastal communities at heightened risk, which may increase with habitat loss. Here we analyse globally the role and cost effectiveness of coral reefs in risk reduction. Meta-analyses reveal that coral reefs provide substantial protection against natural hazards by reducing wave energy by an average of 97%. Reef crests alone dissipate most of this energy (86%). There are 100 million or more people who may receive risk reduction benefits from reefs or bear hazard mitigation and adaptation costs if reefs are degraded. We show that coral reefs can provide comparable wave attenuation benefits to artificial defences such as breakwaters, and reef defences can be enhanced cost effectively. Reefs face growing threats yet there is opportunity to guide adaptation and hazard mitigation investments towards reef restoration to strengthen this first line of coastal defence. PMID:24825660

The effectiveness of coral reefs for coastal hazard risk reduction and adaptation.

PubMed

Ferrario, Filippo; Beck, Michael W; Storlazzi, Curt D; Micheli, Fiorenza; Shepard, Christine C; Airoldi, Laura

2014-05-13

The world's coastal zones are experiencing rapid development and an increase in storms and flooding. These hazards put coastal communities at heightened risk, which may increase with habitat loss. Here we analyse globally the role and cost effectiveness of coral reefs in risk reduction. Meta-analyses reveal that coral reefs provide substantial protection against natural hazards by reducing wave energy by an average of 97%. Reef crests alone dissipate most of this energy (86%). There are 100 million or more people who may receive risk reduction benefits from reefs or bear hazard mitigation and adaptation costs if reefs are degraded. We show that coral reefs can provide comparable wave attenuation benefits to artificial defences such as breakwaters, and reef defences can be enhanced cost effectively. Reefs face growing threats yet there is opportunity to guide adaptation and hazard mitigation investments towards reef restoration to strengthen this first line of coastal defence.

The effectiveness of coral reefs for coastal hazard risk reduction and adaptation

USGS Publications Warehouse

Ferrario, Filippo; Beck, Michael W.; Storlazzi, Curt D.; Micheli, Fiorenza; Shepard, Christine C.; Airoldi, Laura

2014-01-01

The world’s coastal zones are experiencing rapid development and an increase in storms and flooding. These hazards put coastal communities at heightened risk, which may increase with habitat loss. Here we analyse globally the role and cost effectiveness of coral reefs in risk reduction. Meta-analyses reveal that coral reefs provide substantial protection against natural hazards by reducing wave energy by an average of 97%. Reef crests alone dissipate most of this energy (86%). There are 100 million or more people who may receive risk reduction benefits from reefs or bear hazard mitigation and adaptation costs if reefs are degraded. We show that coral reefs can provide comparable wave attenuation benefits to artificial defences such as breakwaters, and reef defences can be enhanced cost effectively. Reefs face growing threats yet there is opportunity to guide adaptation and hazard mitigation investments towards reef restoration to strengthen this first line of coastal defence.

Delinquent-Oriented Attitudes Mediate the Relation Between Parental Inconsistent Discipline and Early Adolescent Behavior

PubMed Central

Halgunseth, Linda C.; Perkins, Daniel F.; Lippold, Melissa A.; Nix, Robert L.

2013-01-01

Although substantial research supports the association between parental inconsistent discipline and early adolescent behaviors, less is understood on mechanisms underlying this relation. This study examined the mediating influence of delinquent-oriented attitudes in early adolescence. Using a longitudinal sample of 324 rural adolescents and their parents, findings revealed that inconsistent discipline in 6th grade predicted an increase in adolescent delinquent-oriented attitudes by 7th grade which, in turn, predicted both an increase in early adolescent antisocial behaviors and a decrease in socially competent behaviors by 8th grade. Therefore, it appears that accepting attitudes toward delinquency may in part develop from experiencing inconsistent discipline at home and may offer a possible explanation as to why early adolescents later engage in more antisocial and less socially competent behaviors. Findings may inform family-based preventive intervention programs that seek to decrease behavior problems and promote social competence in early adolescents. PMID:23544924

Research Priorities in Geriatric Palliative Care: Multimorbidity

PubMed Central

Zulman, Donna M.

2013-01-01

Abstract With global aging and scientific advances extending survival, the number of adults experiencing multiple chronic conditions has grown substantially and is projected to increase by another third between 2000 and 2030. Among the many challenges posed by multimorbidity, some of the most pressing include how to characterize and measure comorbid conditions, understand symptoms and illness burden, and provide person-centered care in the context of competing health care priorities and increasing complexity. In this white paper emanating from a National Institute on Aging supported conference to discuss research gaps at the geriatrics–palliative care interface, the authors review common definitions of multimorbidity; describe the association between multimorbidity and quality of life, functional status, quality of care, and health care utilization; note content and methodological gaps in multimorbidity evidence; and make recommendations regarding research priorities in this area of expanding public health impact. PMID:23777331

Financial dimensions of veterinary medical education: an economist's perspective.

PubMed

Lloyd, James W

2013-01-01

Much discussion has transpired in recent years related to the rising cost of veterinary medical education and the increasing debt loads of graduating veterinarians. Underlying these trends are fundamental changes in the funding structure of higher education in general and of academic veterinary medicine specifically. As a result of the ongoing disinvestment by state governments in higher education, both tuition rates and academic programs have experienced a substantial impact across US colleges and schools of veterinary medicine. Programmatically, the effects have spanned the entire range of teaching, research, and service activities. For graduates, both across higher education and in veterinary medicine specifically, the impact has been steadily increasing levels of student debt. Although the situation is clearly worrisome, viable repayment options exist for these escalating debt loads. In combination with recent income and employment trends for veterinarians, these options provide a basis for cautious optimism for the future.

Attribution of the July–August 2013 heat event in Central and Eastern China to anthropogenic greenhouse gas emissions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, Shuangmei; Zhou, Tianjun; Stone, Dáithí A.

In the midsummer of 2013, Central and Eastern China (CEC) was hit by an extraordinary heat event, with the region experiencing the warmest July-August on record. To explore how human-induced greenhouse gas emissions and natural internal variability contributed to this heat event, we compare observed July-August mean surface air temperature wit h that simulated by climate models. We find that both atmospheric natural variability and anthropogenic factors contributed to this heat event. This extreme warm midsummer was associated with a positive high-pressure anomaly that was closely related to the stochastic behavior of atmospheric circulation. Diagnosis of CMIP5 models and largemore » ensembles of two atmospheric models indicates that human influence has substantially increased the chance of warm mid-summers such as 2013 in CEC, although the exact estimated increase depends on the selection of climate models.« less

Effect of socioeconomic conditions on health care utilization in marital violence: a cross-sectional investigation from the Japanese Study on Stratification, Health, Income, and Neighborhood.

PubMed

Umeda, Maki; Kawakami, Norito; Miller, Elizabeth

2017-02-28

The health-care-seeking process while experiencing marital violence can be significantly influenced by one's socioeconomic status, which limits the availability of resources and opportunities for accessing those resources. This study exploratorily examined the effects of socioeconomic factors on the association between marital violence and health care utilization in Japan. Cross-sectional data on 2,984 male and female community residents aged 25 to 50 years was obtained from the first wave of Japanese Study of Stratification, Health, Income, and Neighborhood (J-SHINE) conducted between 2010 and 2011. Multiple logistic regression analysis was conducted to examine the association between marital violence and health care utilization. Interaction terms were used to examine the moderating effect of educational attainment, household income, and employment status on the association. Mediation analysis was conducted to estimate the magnitude of mediating effects of mastery, social support, and health literacy in relation to the moderating effect of socioeconomic factors. Health care utilization in Japan was more prevalent among those who experienced marital violence (69.4 vs. 65.1%). The association between marital violence and health care utilization differed by employment status at a 0.10 level, while educational attainment and household income did not have substantial influence on health care utilization in the presence of marital violence. None of the psychosocial resources (mastery, health literacy, instrumental support, and informational support) explained the differential association by employment status. This study highlights the increased health care needs of those experiencing marital violence in Japan. The health care needs of the unemployed are potentially unmet in the presence of marital violence. Removing barriers to health care experienced by the unemployed may be an effective strategy for connecting survivors to needed supports and care.

The impact of family formation change on the cognitive, social, and emotional well-being of the next generation.

PubMed

Amato, Paul R

2005-01-01

How have recent changes in U.S. family structure affected the cognitive, social, and emotional well-being of the nation's children? Paul Amato examines the effects of family formation on children and evaluates whether current marriage-promotion programs are likely to meet children's needs. Amato begins by investigating how children in households with both biological parents differ from children in households with only one biological parent. He shows that children growing up with two continuously married parents are less likely to experience a wide range of cognitive, emotional, and social problems, not only during childhood but also in adulthood. Although it is not possible to demonstrate that family structure causes these differences, studies using a variety of sophisticated statistical methods suggest that this is the case. Amato then asks what accounts for the differences between these two groups of children. He shows that compared with other children, those who grow up in stable, two-parent families have a higher standard of living, receive more effective parenting, experience more cooperative co-parenting, are emotionally closer to both parents, and are subjected to fewer stressful events and circumstances. Finally, Amato assesses how current marriage-promotion policies will affect the well-being of children. He finds that interventions that increase the share of children who grow up with both parents would improve the overall well-being of U.S. children only modestly, because children's social or emotional problems have many causes, of which family structure is but one. But interventions that lower only modestly the overall share of U.S. children experiencing various problems could nevertheless lower substantially the number of children experiencing them. Even a small decline in percentages, when multiplied by the many children in the population, is a substantial social benefit.

Mental health in Dutch adolescents: a TRAILS report on prevalence, severity, age of onset, continuity and co-morbidity of DSM disorders.

PubMed

Ormel, J; Raven, D; van Oort, F; Hartman, C A; Reijneveld, S A; Veenstra, R; Vollebergh, W A M; Buitelaar, J; Verhulst, F C; Oldehinkel, A J

2015-01-01

With psychopathology rising during adolescence and evidence suggesting that adult mental health burden is often due to disorders beginning in youth, it is important to investigate the epidemiology of adolescent mental disorders. We analysed data gathered at ages 11 (baseline) and 19 years from the population-based Dutch TRacking Adolescents' Individual Lives Survey (TRAILS) study. At baseline we administered the Achenbach measures (Child Behavior Checklist, Youth Self-Report) and at age 19 years the World Health Organization's Composite International Diagnostic Interview version 3.0 (CIDI 3.0) to 1584 youths. Lifetime, 12-month and 30-day prevalences of any CIDI-DSM-IV disorder were 45, 31 and 15%, respectively. Half were severe. Anxiety disorders were the most common but the least severe whereas mood and behaviour disorders were less prevalent but more severe. Disorders persisted, mostly by recurrence in mood disorders and chronicity in anxiety disorders. Median onset age varied substantially across disorders. Having one disorder increased subjects' risk of developing another disorder. We found substantial homotypic and heterotypic continuity. Baseline problems predicted the development of diagnosable disorders in adolescence. Non-intact families and low maternal education predicted externalizing disorders. Most morbidity concentrated in 5-10% of the sample, experiencing 34-55% of all severe lifetime disorders. At late adolescence, 22% of youths have experienced a severe episode and 23% only mild episodes. This psychopathology is rather persistent, mostly due to recurrence, showing both monotypic and heterotypic continuity, with family context affecting particularly externalizing disorders. High problem levels at age 11 years are modest precursors of incident adolescent disorders. The burden of mental illness concentrates in 5-10% of the adolescent population.

Experiencing a reaching task passively with one arm while adapting to a visuomotor rotation with the other can lead to substantial transfer of motor learning across the arms.

PubMed

Bao, Shancheng; Lei, Yuming; Wang, Jinsung

2017-01-18

The extent of transfer following visuomotor adaptation across the arms is typically limited as compared to that within the same arm. However, we have demonstrated that interlimb transfer can occur nearly completely if one arm performs reaching movements associated with a desired trajectory repeatedly and actively during an initial training session in which the other arm adapts to a novel visuomotor adaptation. Based on that finding, we argued that the absence of instances associated with specific motor effectors is the major reason for limited interlimb transfer. Here, we examined whether providing movement instances associated with one arm passively while adapting to a visuomotor rotation with the opposite arm could also lead to a greater extent of interlimb transfer. We had subjects perform reaching movements either actively or passively with the right arm while adapting to a 30° visuomotor rotation with the left arm (training session), and then had them perform reaching movements under the rotation condition with the right arm (transfer session). Results showed that the extent of transfer observed in the active and the passive training groups was significantly greater than that observed in a control group who only experienced the testing session. This finding suggests that providing effector-specific instances can increase the extent of interlimb transfer substantially, regardless of whether the instances are provided actively or passively. The current finding may have implications for neurorehabilitation targeted for individuals with motor impairment, such as persons with stroke or spinal cord injury. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The child protection and juvenile justice nexus in Australia: A longitudinal examination of the relationship between maltreatment and offending.

PubMed

Malvaso, Catia G; Delfabbro, Paul H; Day, Andrew

2017-02-01

There is convincing evidence that many young people who are in the justice system have had contact with child protection services and that victims of childhood maltreatment are at increased risk of subsequent youth justice involvement. In Australia, however, there have been few longitudinal studies that have examined these associations and relatively less is known in this area. This study examines the overlap between the child protection and youth justice involvement in South Australia, and determines how substantiated maltreatment and variations in these experiences (e.g., the type, timing and recurrence of maltreatment) relate to criminal convictions as a youth. The results show that although the majority of child-protection involved youth do not become convicted offenders, the odds of subsequent convictions are significantly greater both for those with notifications and substantiated maltreatment and for those who had been placed in out-of-home care. Multivariate analyses revealed that the strongest predictors for receiving a conviction among maltreated youth were: male gender, Aboriginal and Torres Strait Islander ethnicity, experiences of physical abuse and emotional abuse, a greater number of substantiations (recurrence), experiencing maltreatment that commenced in childhood and continued into adolescence, and placement in out-of-home care. The mechanisms through which maltreatment might be linked with behavior are then considered, along with directions for future research in this area. Copyright © 2016 Elsevier Ltd. All rights reserved.

Rare disaster information can increase risk-taking

NASA Astrophysics Data System (ADS)

Newell, Ben R.; Rakow, Tim; Yechiam, Eldad; Sambur, Michael

2016-02-01

The recent increase in the frequency and impact of natural disasters highlights the need to provide the public with accurate information concerning disaster prevalence. Most approaches to this problem assume that providing summaries of the nature and scale of disasters will lead people to reduce their exposure to risk. Here we present experimental evidence that such ex post `news reports’ of disaster occurrences can increase the tolerance for risk-taking (which implies that rare events are underweighted). This result is robust across several hundred rounds of choices in a simulated microworld, persists even when the long-run expected value of risky choices is substantially lower than safe choices, and is contingent on providing risk information about disasters that have been (personally) experienced and those that have been avoided (`forgone’ outcomes). The results suggest that augmenting personal experience with information summaries of the number of adverse events (for example, storms, floods) in different regions may, paradoxically, increase the appeal of a disaster-prone region. This finding implies a need to communicate long-term trends in severe climatic events, thereby reinforcing the accumulation of events, and the increase in their associated risks, across time.

Regional Hospital Input Price Indexes

PubMed Central

Freeland, Mark S.; Schendler, Carol Ellen; Anderson, Gerard

1981-01-01

This paper describes the development of regional hospital input price indexes that is consistent with the general methodology used for the National Hospital Input Price Index. The feasibility of developing regional indexes was investigated because individuals inquired whether different regions experienced different rates of increase in hospital input prices. The regional indexes incorporate variations in cost-share weights (the amount an expense category contributes to total spending) associated with hospital type and location, and variations in the rate of input price increases for various regions. We found that between 1972 and 1979 none of the regional price indexes increased at average annual rates significantly different from the national rate. For the more recent period 1977 through 1979, the increase in one Census Region was significantly below the national rate. Further analyses indicated that variations in cost-share weights for various types of hospitals produced no substantial variations in the regional price indexes relative to the national index. We consider these findings preliminary because of limitations in the availability of current, relevant, and reliable data, especially for local area wage rate increases. PMID:10309557

Does Your Library Reflect the Hispanic Culture? A Mapping Analysis

ERIC Educational Resources Information Center

Bailey, Lea

2009-01-01

Many schools are experiencing substantial growth in the Hispanic student population. These students need books written in Spanish and in English as well as bilingual books. The focus of this article is analyzing the content of the books in the collection, whether in English or Spanish. Standards discuss that the diverse needs, multicultural…

Social Class and Elite University Education: A Bourdieusian Analysis

ERIC Educational Resources Information Center

Martin, Nathan Douglas

2010-01-01

The United States experienced a tremendous expansion of higher education after the Second World War. However, this expansion has not led to a substantial reduction to class inequalities at elite universities, where the admissions process is growing even more selective. In his classic studies of French education and society, Pierre Bourdieu…

Bark beetles as agents of change in social-ecological systems

Treesearch

Jesse L Morris; Stuart Cottrell; Christopher J Fettig; R. Justin DeRose; Katherine M Mattor; Vachel A Carter; Jennifer Clear; Jessica Clement; Winslow D Hansen; Jeffrey A Hicke; Philip E Higuera; Alistair WR Seddon; Heikki Seppä; Rosemary L Sherriff; John D Stednick; Steven J Seybold

2018-01-01

Due to recent outbreaks of native bark beetles, forest ecosystems have experienced substantial changes in landscape structure and function, which also affect nearby human populations. As a result, land managers have been tasked with sustaining ecosystem services in impacted areas by considering the best available science, public perceptions, and monitoring data to...

Phonological Awareness Skills in Young Boys with Duchenne Muscular Dystrophy

ERIC Educational Resources Information Center

Waring, Phoebe; Woodyatt, Gail

2011-01-01

Substantial research has detailed the reading deficits experienced by children with Duchenne muscular dystrophy (DMD). Although phonological awareness (PA) is vital in reading development, little is known about PA in the DMD population. This pilot study describes the PA abilities of a group of five young children with DMD, comparing the results…

Spatiotemporal urban land use changes in the Changzhutan Region of Hunan Province in China

USDA-ARS?s Scientific Manuscript database

The Changzhutan region in the north-central part of Hunan Province in China has experienced a rapid urbanization in the past few decades that has led to substantial changes in its environment. In 2007, the National Development and Reform Commission of China designated the metropolitan district of Ch...

Examining the Bicultural Ethnic Identity of Adolescents of a Northeastern Indian Tribe

ERIC Educational Resources Information Center

Brown, Carrie M.; Smirles, Kimberly Eretzian

2005-01-01

The history of northeastern tribes differs substantially from that of other tribes, as northeastern tribes have experienced a longer length of contact with settlers and more intermarriage with non-Indians, producing tribal members of various ethnic backgrounds. American Indians can be considered "bicultural" because they must adapt to two…

New Teacher Mentoring: Hopes and Promise for Improving Teacher Effectiveness

ERIC Educational Resources Information Center

Moir, Ellen; Barlin, Dara; Gless, Janet; Miles, Jan

2009-01-01

Teacher quality is the single most important lever schools have for raising student achievement. A substantial body of research indicates that new teachers are less able than their more experienced colleagues to help students fulfill their academic potential. Yet in many school districts--particularly those in urban settings--as many as half of…

Learning in Cyberspace: An Ethnographic Perspective on the Scottish "Chartered Teacher" Programme

ERIC Educational Resources Information Center

Holligan, Chris

2006-01-01

Although a substantial literature is devoted to the professional development of teachers, emerging dimensions located around e-facilitation techniques have yet to be documented and their implications understood. This paper is based around a case study of a professional group of highly experienced teachers from the state sector who were undertaking…

Fast-tracking implementation through trial design: the case of buprenorphine treatment in Victoria.

PubMed

Bammer, Gabriele; Ritter, Alison; Kutin, Jozica J; Lintzeris, Nicholas

2009-02-01

We investigated how a randomised controlled trial (RCT) could be designed to incorporate features known or thought likely to enhance the uptake of the new treatment into clinical practice post-trial. Between 1999 and 2001, we trialled buprenorphine treatment for heroin dependence in community settings throughout Victoria, using 28 experienced methadone prescribers and 34 pharmacists across 19 sites. In this case study, we describe how we incorporated seven features considered important in treatment uptake: skilled and experienced practitioners, government and policy support, incentives to prescribe the new treatment, specialist support services, clinical guidelines, training programs and patient involvement and information. We also present information showing that uptake of buprenorphine treatment was substantially boosted in Victoria compared with other Australian jurisdictions immediately after the trial in 2001 and that this increase was sustained until at least 2006. While we cannot prove that our trial design was responsible for the increased uptake of buprenorphine treatment in Victoria, we do show that design has been a neglected aspect of clinical trials in terms of enhancing post-trial uptake of the treatment being tested. Those interested in closing the 'know-do' gap between research and practice may wish to further explore this very promising lead. Imaginative linking of features known to enhance treatment uptake to pressing research questions may lead to new information on efficacy, as well as getting valuable drugs into the treatment system more rapidly.

The co-occurrence of physical and cyber dating violence and bullying among teens.

PubMed

Yahner, Jennifer; Dank, Meredith; Zweig, Janine M; Lachman, Pamela

2015-04-01

This study examined the overlap in teen dating violence and bullying perpetration and victimization, with regard to acts of physical violence, psychological abuse, and-for the first time ever-digitally perpetrated cyber abuse. A total of 5,647 youth (51% female, 74% White) from 10 schools participated in a cross-sectional anonymous survey. Results indicated substantial co-occurrence of all types of teen dating violence and bullying. Youth who perpetrated and/or experienced physical, psychological, and cyber bullying were likely to have also perpetrated/experienced physical and sexual dating violence, and psychological and cyber dating abuse. © The Author(s) 2014.

The interplay between interpersonal stress and psychological intimate partner violence over time for young at-risk couples.

PubMed

Shortt, Joann Wu; Capaldi, Deborah M; Kim, Hyoun K; Tiberio, Stacey S

2013-04-01

The substantial number of young people in romantic relationships that involve intimate partner violence, a situation deleterious to physical and mental health, has resulted in increased attention to understanding the links between risk factors and course of violence. The current study examined couples' interpersonal stress related to not liking partners' friends and not getting along with parents as contextual factors associated with couples' psychological partner violence and determined whether and when couples' friend and parent stress increased the likelihood of couples' psychological partner violence. A linear latent growth curve modeling approach was used with multiwave measures of psychological partner violence, friend stress, parent stress, and relationship satisfaction obtained from 196 men at risk for delinquency and their women partners over a 12-year period. At the initial assessment, on average, the men were age 21.5 years and the women were age 21 years. Findings indicated that couples experiencing high levels of friend and parent stress were more likely to engage in high levels of psychological partner violence and that increases in couples' friend stress predicted increases in couples' partner violence over time, even when accounting for the couples' relationship satisfaction, marital status, children in the home, and financial strain. Interactive effects were at play when the couples were in their early 20s, with couples being most at risk for increases in psychological partner violence if they experienced both high friend stress and low relationship satisfaction. Couples' friend stress had the greatest effect on psychological partner violence when the couples were in their early to mid 20s when levels of friend stress were high. As the couples reached their 30s, low relationship satisfaction became the leading predictor of couples' psychological partner violence.

The Interplay Between Interpersonal Stress and Psychological Intimate Partner Violence Over Time for Young At-Risk Couples

PubMed Central

Capaldi, Deborah M.; Kim, Hyoun K.; Tiberio, Stacey S.

2013-01-01

The substantial number of young people in romantic relationships that involve intimate partner violence, a situation deleterious to physical and mental health, has resulted in increased attention to understanding the links between risk factors and course of violence. The current study examined couples’ interpersonal stress related to not liking partners’ friends and not getting along with parents as contextual factors associated with couples’ psychological partner violence and determined whether and when couples’ friend and parent stress increased the likelihood of couples’ psychological partner violence. A linear latent growth curve modeling approach was used with multiwave measures of psychological partner violence, friend stress, parent stress, and relationship satisfaction obtained from 196 men at risk for delinquency and their women partners over a 12-year period. At the initial assessment, on average, the men were age 21.5 years and the women were age 21 years. Findings indicated that couples experiencing high levels of friend and parent stress were more likely to engage in high levels of psychological partner violence and that increases in couples’ friend stress predicted increases in couples’ partner violence over time, even when accounting for the couples’ relationship satisfaction, marital status, children in the home, and financial strain. Interactive effects were at play when the couples were in their early 20s, with couples being most at risk for increases in psychological partner violence if they experienced both high friend stress and low relationship satisfaction. Couples’ friend stress had the greatest effect on psychological partner violence when the couples were in their early to mid 20s when levels of friend stress were high. As the couples reached their 30s, low relationship satisfaction became the leading predictor of couples’ psychological partner violence. PMID:23358887

The impact of migration and antimicrobial resistance on the transmission dynamics of typhoid fever in Kathmandu, Nepal: A mathematical modelling study

PubMed Central

Bowles, Cayley C.; Grenfell, Bryan T.; Basnyat, Buddha; Arjyal, Amit; Dongol, Sabina; Karkey, Abhilasha; Baker, Stephen; Pitzer, Virginia E.

2017-01-01

Background A substantial proportion of the global burden of typhoid fever occurs in South Asia. Kathmandu, Nepal experienced a substantial increase in the number of typhoid fever cases (caused by Salmonella Typhi) between 2000 and 2003, which subsequently declined but to a higher endemic level than in 2000. This epidemic of S. Typhi coincided with an increase in organisms with reduced susceptibility against fluoroquinolones, the emergence of S. Typhi H58, and an increase in the migratory population in Kathmandu. Methods We devised a mathematical model to investigate the potential epidemic drivers of typhoid in Kathmandu and fit this model to weekly data of S. Typhi cases between April 1997 and June 2011 and the age distribution of S. Typhi cases. We used this model to determine if the typhoid epidemic in Kathmandu was driven by heightened migration, the emergence of organisms with reduced susceptibility against fluoroquinolones or a combination of these factors. Results Models allowing for the migration of susceptible individuals into Kathmandu alone or in combination with the emergence of S. Typhi with reduced susceptibility against fluoroquinolones provided a good fit for the data. The emergence of organisms with reduced susceptibility against fluoroquinolones organisms alone, either through an increase in disease duration or increased transmission, did not fully explain the pattern of S. Typhi infections. Conclusions Our analysis is consistent with the hypothesis that the increase in typhoid fever in Kathmandu was associated with the migration of susceptible individuals into the city and aided by the emergence of reduced susceptibility against fluoroquinolones. These data support identifying and targeting migrant populations with typhoid immunization programmes to prevent transmission and disease. PMID:28475605

The impact of migration and antimicrobial resistance on the transmission dynamics of typhoid fever in Kathmandu, Nepal: A mathematical modelling study.

PubMed

Saad, Neil J; Bowles, Cayley C; Grenfell, Bryan T; Basnyat, Buddha; Arjyal, Amit; Dongol, Sabina; Karkey, Abhilasha; Baker, Stephen; Pitzer, Virginia E

2017-05-01

A substantial proportion of the global burden of typhoid fever occurs in South Asia. Kathmandu, Nepal experienced a substantial increase in the number of typhoid fever cases (caused by Salmonella Typhi) between 2000 and 2003, which subsequently declined but to a higher endemic level than in 2000. This epidemic of S. Typhi coincided with an increase in organisms with reduced susceptibility against fluoroquinolones, the emergence of S. Typhi H58, and an increase in the migratory population in Kathmandu. We devised a mathematical model to investigate the potential epidemic drivers of typhoid in Kathmandu and fit this model to weekly data of S. Typhi cases between April 1997 and June 2011 and the age distribution of S. Typhi cases. We used this model to determine if the typhoid epidemic in Kathmandu was driven by heightened migration, the emergence of organisms with reduced susceptibility against fluoroquinolones or a combination of these factors. Models allowing for the migration of susceptible individuals into Kathmandu alone or in combination with the emergence of S. Typhi with reduced susceptibility against fluoroquinolones provided a good fit for the data. The emergence of organisms with reduced susceptibility against fluoroquinolones organisms alone, either through an increase in disease duration or increased transmission, did not fully explain the pattern of S. Typhi infections. Our analysis is consistent with the hypothesis that the increase in typhoid fever in Kathmandu was associated with the migration of susceptible individuals into the city and aided by the emergence of reduced susceptibility against fluoroquinolones. These data support identifying and targeting migrant populations with typhoid immunization programmes to prevent transmission and disease.

Trauma and PTSD rates in an irish psychiatric population

PubMed Central

Wilson, Fiona E; Hennessy, Eilis; Dooley, Barbara; Kelly, Brendan D; Ryan, Dermot A

2013-01-01

Although Western mental health services are increasingly finding themselves concerned with assisting traumatized individuals migrating from other countries, trauma and posttraumatic stress disorder (PTSD) are under-detected and undiagnosed in psychiatric populations. This study examined and compared rates of traumatic experiences, frequency of traumatic events, trauma symptomatology levels, rates of torture, rates of PTSD and chart documentation of trauma and PTSD between (a) Irish and migrant service-users and (b) forced migrant and voluntary migrant service-users in Dublin, Ireland. Data were gathered from 178 psychiatric outpatients attending using a sociodemographic questionnaire, the Harvard Trauma Questionnaire-Revised Cambodian Version and the SCID-I/P. A substantial number of service-users had experienced at least one lifetime trauma (71.3%), and a high percentage of both the Irish (47.4%) and migrant groups (70.3%) of service-users had experienced two or more events. Overall, analyses comparing rates between Irish, forced migrant and voluntary migrant service-users found that forced migrants displayed more traumatic life events, posttraumatic symptoms, and higher levels of PTSD than their voluntary migrant and Irish counterparts, with over 50% experiencing torture prior to arrival in Ireland. The lifetime rate of PTSD in the overall sample was 15.7% but only 53.57% of cases were documented in patient charts. The results of this study are informative about the nature and extent of the problem of trauma and PTSD among migrant mental health service users as well as highlighting the under-detected levels of trauma among native-born service users. PMID:28228990

Critical care nurses management of prolonged weaning: an interview study.

PubMed

Cederwall, Carl-Johan; Plos, Kaety; Rose, Louise; Dübeck, Amanda; Ringdal, Mona

2014-09-01

For most critically ill patients requiring mechanical ventilation in the intensive care unit (ICU) weaning is uncomplicated. For the remainder, weaning is a challenge and may result in further complications and increased risk of mortality. Critical care nurses (CCNs) require substantial knowledge and experience to manage patients experiencing prolonged weaning. The aim of this study was to explore CCNs approach for management of patients experiencing prolonged weaning in the ICU. A descriptive qualitative design. Semi-structured interviews with 19 experienced CCNs were conducted. Data were analysed using content analysis. Participants used various strategies for weaning that were grouped into four categories: individualized planning for the weaning process, assessing patient's capacity, managing the process and team interaction. The overall theme that emerged was: CCNs drive the weaning process using both a patient centred and targeted approach. CCNs in these ICUs performed weaning using a patient centred approach to plan, initiate, assess and establish a holistic weaning process. Team collaboration among all health care practitioners was important. CCNs have a key role in prioritizing weaning and driving the process forward. Closeness to the patient and a key role in management of the mechanical ventilated patient in ICU gives the CCN unique potential to develop and create models and tools for prolonged weaning. These tools, specially designed for patients undergoing prolonged weaning, would give focus on continuous planning, collaborating, managing and evaluation in the process of liberating patients from mechanical ventilation. © 2014 British Association of Critical Care Nurses.

The effect of discontinued use of antimicrobial growth promoters on the risk of therapeutic antibiotic treatment in Danish farrow-to-finish pig farms

PubMed Central

VIGRE, H.; LARSEN, P. B.; ANDREASEN, M.; CHRISTENSEN, J.; JORSAL, S. E.

2008-01-01

SUMMARY This study estimated the effect of discontinued use of antimicrobial growth promoters (duAGPs) on the risk of antibiotic treatment for diarrhoea, arthritis, pneumonia, unthriving and miscellaneous disorders in Danish pig farms. The estimation was done in a case-crossover study comparing: (1) the proportion of days per farm where treatment was performed (PDT) and (2) the proportion of pigs treated per day per farm at days where treatment was performed (PPT) before and after duAGPs at 68 farrow-to-finish farms. The farms were selected using a two-stage (veterinarian/farm) convenience sampling. On average, during the first year after duAGPs there was a significant increase in the risk of antibiotic treatment for diarrhoea (PDT: OR 2·5, 95% CI 1·7–3·8; PPT: OR 1·6, 95% CI 1·1–2·2). However, the effect varied among farms – some farms experienced substantial problems, while others experienced few problems after duAGPs. No effect was identified for the risk of treatment for other diseases. PMID:17335634

Gender-based differences in injecting drug use by young adults who experienced maltreatment in childhood: Findings from an Australian birth cohort study.

PubMed

Abajobir, Amanuel Alemu; Kisely, Steve; Williams, Gail; Clavarino, Alexandra; Strathearn, Lane; Najman, Jake Moses

2017-04-01

Childhood maltreatment has been associated with a range of adverse mental and psychosocial outcomes, but its association with subsequent injecting drug use (IDU) is less clear. This study investigates the associations between specific and multiple forms of substantiated childhood maltreatment and IDU reported at 21 years. The Mater-University of Queensland Study of Pregnancy is a prospective birth cohort study. It recruited pregnant women at their first antenatal clinic visit and collected data on their children at 21 years. Data from 3750 participants (1769 males and 1981 females) were analysed using agency substantiated childhood maltreatment from birth to 14 years of age and self-reports of ever IDU at 21 years. We used multivariable logistic regression analyses to control for possible confounders. The sample's mean age was 20.6 years. Some 4.1% (n=72) of males and 4.6% (n=91) of females had experienced substantiated childhood maltreatment. The prevalence of IDU was 6.6% (n=118) and 4.6% (n=91) for males and females, respectively. In adjusted models, all forms of substantiated childhood maltreatment, with the exception of sexual abuse, were associated with IDU in females (adjusted odds ratios (AORs)=2.69-3.02) but only emotional abuse (AOR=2.51) was associated with IDU in males. Multiply occurring forms of childhood maltreatment were also associated with IDU in females (AORs=2.36-3.41) but not in males. Injecting drug use appears to be an adverse outcome of childhood maltreatment particularly in females. Additional research is needed to better understand why females appear to be more affected than males. Copyright © 2017 Elsevier B.V. All rights reserved.

Population health status of South Asian and African-Caribbean communities in the United Kingdom.

PubMed

Calvert, Melanie; Duffy, Helen; Freemantle, Nick; Davis, Russell; Lip, Gregory Y H; Gill, Paramjit

2012-04-25

Population health status scores are routinely used to inform economic evaluation and evaluate the impact of disease and/or treatment on health. It is unclear whether the health status in black and minority ethnic groups are comparable to these population health status data. The aim of this study was to evaluate health-status in South Asian and African-Caribbean populations. Cross-sectional study recruiting participants aged ≥ 45 years (September 2006 to July 2009) from 20 primary care centres in Birmingham, United Kingdom.10,902 eligible subjects were invited, 5,408 participated (49.6%). 5,354 participants had complete data (49.1%) (3442 South Asian and 1912 African-Caribbean). Health status was assessed by interview using the EuroQoL EQ-5D. The mean EQ-5D score in South Asian participants was 0.91 (standard deviation (SD) 0.18), median score 1 (interquartile range (IQR) 0.848 to 1) and in African-Caribbean participants the mean score was 0.92 (SD 0.18), median 1 (IQR 1 to 1). Compared with normative data from the UK general population, substantially fewer African-Caribbean and South Asian participants reported problems with mobility, usual activities, pain and anxiety when stratified by age resulting in higher average health status estimates than those from the UK population. Multivariable modelling showed that decreased health-related quality of life (HRQL) was associated with increased age, female gender and increased body mass index. A medical history of depression, stroke/transient ischemic attack, heart failure and arthritis were associated with substantial reductions in HRQL. The reported HRQL of these minority ethnic groups was substantially higher than anticipated compared to UK normative data. Participants with chronic disease experienced significant reductions in HRQL and should be a target for health intervention.

The Influence of Stressor Exposure and Psychosocial Resources on the Age-Anger Relationship.

PubMed

Brown, Robyn Lewis

2016-12-01

This study examined the processes linking age, stressor exposure, psychosocial coping resources, and two dimensions of anger proneness (i.e., experienced anger and expressed anger). Longitudinal change regression analysis of data from a two-wave community panel study including a sample of people aged 18 to 93 ( N = 1,473) is performed. Age is significantly associated with declines in both experienced anger and expressed anger over the 3-year study period. These associations are substantially mediated by the lower levels of chronic stressors and discrimination-related stressors experienced among older adults. In contrast, self-esteem amplifies the association between age and expressed anger. These findings clarify the circumstances in which age matters most for changes over time in the experience and expression of anger. They highlight how certain forms of stressor exposure and psychosocial resources are linked with anger proneness and in ways that vary by age.

Violence to Others, Violent Self-Victimization, and Violent Victimization by Others Among Persons With a Mental Illness.

PubMed

Monahan, John; Vesselinov, Roumen; Robbins, Pamela Clark; Appelbaum, Paul S

2017-05-01

This research examined the frequency of and characteristics associated with three forms of violence among persons with mental illness-violence directed at others, self-directed violence, and violence directed at them by others. Previously unreported data from a follow-up sample of 951 patients from the MacArthur Violence Risk Assessment Study were analyzed to characterize involvement in violence directed at others, self-directed violence, and violence directed at them by others. Most patients (58%) experienced at least one form of violence, 28% experienced at least two forms, and 7% experienced all three forms. Several diagnostic, social, and historical variables distinguished the groups. Given the substantial overlap among the three forms of violence, clinicians should routinely screen patients who report one form for the occurrence of the other two. Co-occurrence of several forms of violence may require a package of interventions with components geared to each.

Comparative Analysis of Head Impact in Contact and Collision Sports

PubMed Central

Reynolds, Bryson B.; Patrie, James; Henry, Erich J.; Goodkin, Howard P.; Broshek, Donna K.; Wintermark, Max

2017-01-01

Abstract As concerns about head impact in American football have grown, similar concerns have started to extend to other sports thought to experience less head impact, such as soccer and lacrosse. However, the amount of head impact experienced in soccer and lacrosse is relatively unknown, particularly compared with the substantial amount of data from football. This pilot study quantifies and compares head impact from four different types of sports teams: college football, high school football, college soccer, and college lacrosse. During the 2013 and 2014 seasons, 61 players wore mastoid patch accelerometers to quantify head impact during official athletic events (i.e., practices and games). In both practices and games, college football players experienced the most or second-most impacts per athletic event, highest average peak resultant linear and rotational acceleration per impact, and highest cumulative linear and rotational acceleration per athletic event. For average peak resultant linear and rotational acceleration per individual impact, college football was followed by high school football, then college lacrosse, and then college soccer, with similar trends in both practices and games. In the four teams under study, college football players experienced a categorically higher burden of head impact. However, for cumulative impact burden, the high school football cohort was not significantly different from the college soccer cohort. The results suggest that head impact in sport substantially varies by both the type of sport (football vs. soccer vs. lacrosse) and level of play (college vs. high school). PMID:27541183

Human-caused Indo-Pacific warm pool expansion

PubMed Central

Weller, Evan; Min, Seung-Ki; Cai, Wenju; Zwiers, Francis W.; Kim, Yeon-Hee; Lee, Donghyun

2016-01-01

The Indo-Pacific warm pool (IPWP) has warmed and grown substantially during the past century. The IPWP is Earth’s largest region of warm sea surface temperatures (SSTs), has the highest rainfall, and is fundamental to global atmospheric circulation and hydrological cycle. The region has also experienced the world’s highest rates of sea-level rise in recent decades, indicating large increases in ocean heat content and leading to substantial impacts on small island states in the region. Previous studies have considered mechanisms for the basin-scale ocean warming, but not the causes of the observed IPWP expansion, where expansion in the Indian Ocean has far exceeded that in the Pacific Ocean. We identify human and natural contributions to the observed IPWP changes since the 1950s by comparing observations with climate model simulations using an optimal fingerprinting technique. Greenhouse gas forcing is found to be the dominant cause of the observed increases in IPWP intensity and size, whereas natural fluctuations associated with the Pacific Decadal Oscillation have played a smaller yet significant role. Further, we show that the shape and impact of human-induced IPWP growth could be asymmetric between the Indian and Pacific basins, the causes of which remain uncertain. Human-induced changes in the IPWP have important implications for understanding and projecting related changes in monsoonal rainfall, and frequency or intensity of tropical storms, which have profound socioeconomic consequences. PMID:27419228

Human-caused Indo-Pacific warm pool expansion.

PubMed

Weller, Evan; Min, Seung-Ki; Cai, Wenju; Zwiers, Francis W; Kim, Yeon-Hee; Lee, Donghyun

2016-07-01

The Indo-Pacific warm pool (IPWP) has warmed and grown substantially during the past century. The IPWP is Earth's largest region of warm sea surface temperatures (SSTs), has the highest rainfall, and is fundamental to global atmospheric circulation and hydrological cycle. The region has also experienced the world's highest rates of sea-level rise in recent decades, indicating large increases in ocean heat content and leading to substantial impacts on small island states in the region. Previous studies have considered mechanisms for the basin-scale ocean warming, but not the causes of the observed IPWP expansion, where expansion in the Indian Ocean has far exceeded that in the Pacific Ocean. We identify human and natural contributions to the observed IPWP changes since the 1950s by comparing observations with climate model simulations using an optimal fingerprinting technique. Greenhouse gas forcing is found to be the dominant cause of the observed increases in IPWP intensity and size, whereas natural fluctuations associated with the Pacific Decadal Oscillation have played a smaller yet significant role. Further, we show that the shape and impact of human-induced IPWP growth could be asymmetric between the Indian and Pacific basins, the causes of which remain uncertain. Human-induced changes in the IPWP have important implications for understanding and projecting related changes in monsoonal rainfall, and frequency or intensity of tropical storms, which have profound socioeconomic consequences.

Quantification of sudden oak death tree mortality in the Big Sur ecoregion of California

Treesearch

Douglas A. Shoemaker; Christopher B. Oneal; David M. Rizzo; Ross K. Meentemeyer

2008-01-01

Big Sur is one of the most ecologically diverse regions in California and well recognized as a biodiversity hotspot for global conservation priority. Currently the region is experiencing substantial environmental change due to the invasion of Phytophthora ramorum, the plant pathogen causing the forest disease known as sudden oak death. First...

When Cultures Clash: The Story of One School's Journey from Acculturation to Understanding

ERIC Educational Resources Information Center

Heinrich, Jill

2018-01-01

This qualitative case study examines the conflicts and challenges that one American junior high school experienced when a substantial number of African-American families migrated to the community from Chicago to secure Section 8 housing; their housing projects had recently been felled through the auspices of HOPE VI (Housing Opportunities for…

The New Teacher Induction Experience: Tension between Curricular and Programmatic Demands and the Need for Immediate Help

ERIC Educational Resources Information Center

Mitchell, Douglas E.; Howard, Barbara; Meetze-Hall, Melissa; Hendrick, Linda Scott; Sandlin, Ruth

2017-01-01

Throughout the history of California's Beginning Teacher Support and Assessment (BTSA) program, new teachers have reported experiencing substantial tension between the curricular and programmatic demands arising from their induction programs' formative assessment systems and the immediate coaching help they need to deal with day-to-day classroom…

Lessons from Elsewhere? The Evolution of the Labour Academy School Concept, 1997-2010

ERIC Educational Resources Information Center

Fenwick-Sehl, Laura

2013-01-01

In the past 25 years, the English education system has experienced a substantial growth in alternative provision, that is, publicly funded schools that accept students from the general population without selection, but provide an educational setting different to the traditional, locally provided schools. Introduced in 2000 by the Labour Party,…

(Re)thinking Equity: The Spatial and Racial Dynamics of Managing Learning and Learning to Manage

ERIC Educational Resources Information Center

Shore, Sue

2006-01-01

The vocational education and training (VET) sector has experienced substantial change in the past decade, characterised by ascendant industry-driven needs and mantras of flexibility and responsiveness. A number of public policies underpin these changes and simultaneously point to the need to manage diverse employing bodies, industry standards,…

Fire history of Tenderfoot Creek Experimental Forest, Lewis and Clark National Forest

Treesearch

Stephen W. Barrett

1993-01-01

Lodgepole pine (Pinus contorta Dougl. var. latifolia) forests in the northern Rocky Mountains have experienced substantial variation in presettlement fire patterns (Arno 1976, Sneck 1977, Arno 1980, Romme 1982, Romme and Despain 1989, Barrett and Arno 1991, Barrett et a1. 1991, Barrett [in prep]). On relatively productive habitat types at lower elevations, short- to...

Using kinetic models to predict thermal degradation of fire-retardant-treated plywood roof sheathing

Treesearch

Patricia Lebow; Jerrold E. Winandy; Patricia K. Lebow

2003-01-01

Between 1985-1995 a substantial number of multifamily housing units in the Eastern and Southern U.S. experienced problems with thermally degraded fire-retardant-treated (FRT) plywood roof sheathing. A series of studies conducted at the USDA Forest Service, Forest Products Laboratory (FPL), examined the materials, chemical mechanisms, and process implications and has...

Some issues on modeling atmospheric turbulence experienced by helicopter rotor blades

NASA Technical Reports Server (NTRS)

Costello, Mark; Gaonkar, G. H.; Prasad, J. V. R.; Schrage, D. P.

1992-01-01

The atmospheric turbulence velocities seen by nonrotating aircraft components and rotating blades can be substantially different. The differences are due to the spatial motion of the rotor blades, which move fore and aft through the gust waves. Body-fixed atmospheric turbulence refers to the actual atmospheric turbulence experienced by a point fixed on a nonrotating aircraft component such as the aircraft's center of gravity or the rotor hub, while blade-fixed atmospheric turbulence refers to the atmospheric turbulence experienced by an element of the rotating rotor blade. An example is presented, which, though overly simplified, shows important differences between blade- and body-fixed rotorcraft atmospheric turbulence models. All of the information necessary to develop the dynamic equations describing the atmospheric turbulence velocity field experienced by an aircraft is contained in the atmospheric turbulence velocity correlation matrix. It is for this reason that a generalized formulation of the correlation matrix describing atmospheric turbulence that a rotating blade encounters is developed. From this correlation matrix, earlier treated cases restricted to a rotor flying straight and level directly into the mean wind can be recovered as special cases.

Transformer current sensor for superconducting magnetic coils

DOEpatents

Shen, S.S.; Wilson, C.T.

1985-04-16

The present invention is a current transformer for operating currents larger than 2kA (two kiloamps) that is capable of detecting a millivolt level resistive voltage in the presence of a large inductive voltage. Specifically, the present invention includes substantially cylindrical primary turns arranged to carry a primary current and substantially cylindrical secondary turns arranged coaxially with and only partially within the primary turns, the secondary turns including an active winding and a dummy winding, the active and dummy windings being coaxial, longitudinally separated and arranged to mutually cancel voltages excited by commonly experienced magnetic fields, the active winding but not the dummy winding being arranged within the primary turns.

Magnetic Properties Improvement of Die-upset Nd-Fe-B Magnets by Dy-Cu Press Injection and Subsequent Heat Treatment

NASA Astrophysics Data System (ADS)

Wang, Zexuan; Ju, Jinyun; Wang, Jinzhi; Yin, Wenzong; Chen, Renjie; Li, Ming; Jin, Chaoxiang; Tang, Xu; Lee, Don; Yan, Aru

2016-12-01

Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivity and remanent magnetization of the Dy-Cu press injected magnets increased substantially in comparison with those of the annealed reference magnets, which is distinct from the reported experimental results on heavy rare-earth diffusion. To study the mechanism, we analyzed the texture evolution in high-temperature annealed die-upset magnets, which had significant impact on the improvement of remanent magnetization. On basis of the results, we find that the new structures are strongly interlinked with the initial structures. With injecting Dy-Cu eutectic alloy, an optimized initial microstructure was achieved in the near-surface diffused regions, which made preparations for the subsequent texture improvement. Besides, the Dy gradient distribution of near-surface regions of the Dy-Cu press injected magnets was also investigated. By controlling the initial microstructure and subsequent diffusion process, a higher performance magnet is expected to be obtained.

Magnetic Properties Improvement of Die-upset Nd-Fe-B Magnets by Dy-Cu Press Injection and Subsequent Heat Treatment

PubMed Central

Wang, Zexuan; Ju, Jinyun; Wang, Jinzhi; Yin, Wenzong; Chen, Renjie; Li, Ming; Jin, Chaoxiang; Tang, Xu; Lee, Don; Yan, Aru

2016-01-01

Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivity and remanent magnetization of the Dy-Cu press injected magnets increased substantially in comparison with those of the annealed reference magnets, which is distinct from the reported experimental results on heavy rare-earth diffusion. To study the mechanism, we analyzed the texture evolution in high-temperature annealed die-upset magnets, which had significant impact on the improvement of remanent magnetization. On basis of the results, we find that the new structures are strongly interlinked with the initial structures. With injecting Dy-Cu eutectic alloy, an optimized initial microstructure was achieved in the near-surface diffused regions, which made preparations for the subsequent texture improvement. Besides, the Dy gradient distribution of near-surface regions of the Dy-Cu press injected magnets was also investigated. By controlling the initial microstructure and subsequent diffusion process, a higher performance magnet is expected to be obtained. PMID:27922060

Risks of Mortality and Morbidity from Worldwide Terrorism: 1968-2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bogen, K T; Jones, E D

Worldwide data on terrorist incidents between 1968 and 2004 gathered by the RAND corporation and the Oklahoma City National Memorial Institute for the Prevention of Terrorism (MIPT) were assessed for patterns and trends in morbidity/mortality. Adjusted data analyzed involve a total of 19,828 events, 7,401 ''adverse'' events (each causing {ge}1 victim), and 86,568 ''casualties'' (injuries) of which 25,408 were fatal. Most terror-related adverse events, casualties and deaths involved bombs and guns. Weapon-specific patterns and terror-related risk levels in Israel (IS) have differed markedly from those of all other regions combined (OR). IS had a fatal fraction of casualties about halfmore » that of OR, but has experienced relatively constant lifetime terror-related casualty risks on the order of 0.5%--a level 2 to 3 orders of magnitude more than those experienced in OR that increased {approx}100-fold over the same period. Individual event fatality has increased steadily, the median increasing from 14 to 50%. Lorenz curves obtained indicate substantial dispersion among victim/event rates: about half of all victims were caused by the top 2.5% (or 10%) of harm-ranked events in OR (or IS). Extreme values of victim/event rates were approximated fairly well by generalized Pareto models (typically used to fit to data on forest fires, sea levels, earthquakes, etc.). These results were in turn used to forecast maximum OR- and IS-specific victims/event rates through 2080, illustrating empirically based methods that could be applied to improve strategies to assess, prevent and manage terror-related risks and consequences.« less

Risks of mortality and morbidity from worldwide terrorism: 1968-2004.

PubMed

Bogen, Kenneth T; Jones, Edwin D

2006-02-01

Worldwide data on terrorist incidents between 1968 and 2004 gathered by the RAND Corporation and the Oklahoma City National Memorial Institute for the Prevention of Terrorism (MIPT) were assessed for patterns and trends in morbidity/mortality. Adjusted data analyzed involve a total of 19,828 events, 7,401 "adverse" events (each causing >or= 1 victim), and 86,568 "casualties" (injuries), of which 25,408 were fatal. Most terror-related adverse events, casualties, and deaths involved bombs and guns. Weapon-specific patterns and terror-related risk levels in Israel (IS) have differed markedly from those of all other regions combined (OR). IS had a fatal fraction of casualties about half that of OR, but has experienced relatively constant lifetime terror-related casualty risks on the order of 0.5%--a level 2 to 3 orders of magnitude more than those experienced in OR that increased approximately 100-fold over the same period. Individual event fatality has increased steadily, the median increasing from 14% to 50%. Lorenz curves obtained indicate substantial dispersion among victim/event rates: about half of all victims were caused by the top 2.5% (or 10%) of harm-ranked events in OR (or IS). Extreme values of victim/event rates were approximated fairly well by generalized Pareto models (typically used to fit to data on forest fires, sea levels, earthquakes, etc.). These results were in turn used to forecast maximum OR- and IS-specific victims/event rates through 2080, illustrating empirically-based methods that could be applied to improve strategies to assess, prevent, and manage terror-related risks and consequences.

Myrtle Beach Air Force Base Community Redevelopment Plan

DTIC Science & Technology

1993-01-01

Potential U ses .......................................... 3-2 3-2 Ranking of Potential Uses ....................................... 3-3 3-3 Tourism M...economy has been primarily resort and tourism - and, to a lesser degree, retirement. During the 1980’s, the Grand Strand experienced substantial...economic orientation toward tourism . Last year, the Grand Strand generated $1.7 billion in total tourism spending from the tourist market. These visitors

Indicators of Population Viabllity in Red Spruce, Picea rubens. I. Reproductive Traits and Fecundity

Treesearch

A. Mosseler; J.E. Major; J.D. Simpson; B. Daigle; K. Lange; Y.S. Park; K.H Johnsen; O.P. Rajora

2000-01-01

Red spruce (Picea rubens Sarg.) has experienced a substantial decline across most of its range in eastern North America over the past centmy and probably also in the disjunct Ontario populations where it now occurs only in small isolated stands. Measurements of cone and seed traits from natural populations were used as indicators of the...

Root-collar diameter and third-year survival of three bottomland hardwoods planted on former agricultural fields in the Lower Mississippi Alluvial Valley

Treesearch

Emile S. Gardiner; Douglass F. Jacobs; Ronald P. Overton; George Hernandez

2009-01-01

Athough the Lower Mississippi Alluvial Valley (LMAV) has experienced substantial afforestation of former agricultural fields during the past 2 decades, seedling standards that support satisfactory outplanting performance of bottomland hardwood tree species are not available. A series of experimental plantations, established on three afforestation sites in the LMAV,...

Redundancy and Replication Help Make Your Systems Stress-Free

ERIC Educational Resources Information Center

Mitchell, Erik

2011-01-01

In mid-April, Amazon EC2 services had a small problem. Apparently, a large swath of its cloud computing environment had such substantial trouble that a number of customers had server issues. A number of high-profile sites, including Reddit, Evite, and Foursquare, went down when Amazon experienced issues in their US East 1a region (Justinb 2011).…

School-to-Work Transition in Hong Kong: Suggestions for the Vocationalization of Secondary Education

ERIC Educational Resources Information Center

Lee, John Chi-Kin; Pavlova, Margarita; Maclean, Rupert

2016-01-01

Since the start of the new century, basic and senior schools have started to encounter curriculum reforms, and vocational education has experienced substantial changes. Based on the changing context in the past 10 or more years, this study examines the issue of school-to-work transition from the perspective of the vocationalization of secondary…

"Standing on the Periphery": Cooperating Teachers' Perceptions and Responses to the Role of Supervision

ERIC Educational Resources Information Center

Young, Ann-Marie; MacPhail, Ann

2015-01-01

Research has shown that teachers can derive substantial benefits from the role of cooperating teacher (CT) and many experienced teachers have made positive changes to their teaching as a result, often engaging as co-learners. The aim of this paper is to examine the intricacies of the trajectory of CTs in terms of the development of their…

Alteration of belowground carbon dynamics by nitrogen addition in southern California mixed conifer forests

Treesearch

N.S. Nowinski; S.E. Trumbore; G. Jimenez; M.E. Fenn

2009-01-01

Nitrogen deposition rates in southern California are the highest in North America and have had substantial effects on ecosystem functioning. We document changes in the belowground C cycle near ponderosa pine trees experiencing experimental nitrogen (N) addition (50 and 150 kg N ha−1 a−1 as slow release urea since 1997) at two end‐member...

The mineralogy of global magnetic anomalies

NASA Technical Reports Server (NTRS)

Haggerty, S. E. (Principal Investigator)

1982-01-01

The Curie Balance was brought to operational stage and is producing data of a preliminary nature. Substantial problems experienced in the assembly and initial operation of the instrument were, for the most part, rectified, but certain problems still exist. Relationships between the geology and the gravity and MAGSAT anomalies of West Africa are reexamined in the context of a partial reconstruction of Gondwanaland.

Navigating California's Stormy Seas: A Multi-Case Study of Presidential Leadership in the Midst of Fiscal Crisis

ERIC Educational Resources Information Center

Clark, Kristin Lane

2012-01-01

California's fiscal crisis is more severe than those of past decades and as a result, the State's community colleges have experienced substantial cuts to their budgets. Multiple reductions in funding since 2008 have forced colleges to scale back their course offerings, reduce personnel, and limit student services. This lack of funding has created…

Health and Disease at Age 100.

PubMed

Jopp, Daniela S; Boerner, Kathrin; Rott, Christoph

2016-03-25

Centenarian studies from around the world have shown that reaching age 100 typically involves substantial health issues. The present study adds to the existing knowledge from other countries by describing health conditions in German centenarians. A total of 112 centenarians or their primary contacts provided information on acute and chronic health conditions and pain in the context of the Second Heidelberg Centenarian Study (mean age = 100.45 years, standard deviation [SD] = 0.47, 89% females). Participants showed high comorbidity, with an average of five illnesses (mean = 5.3; SD = 2.20). Health conditions with highest prevalence were sensory (vision, hearing; 94%), mobility (72%) and musculoskeletal conditions (60%). Cardiovascular conditions (57%) and urinary system ailments (55%) were also common. Pain was experienced often by 30% of the participants. Of those reporting any pain, 36% indicated pain exceeding bearable levels. German centenarians experienced a substantial number of ill nesses, dominated by sensory and mobility conditions. Cardiovascular diseases were the only potentially lethal illnesses with high prevalence. Evidence of unaddressed pain seems alarming, requiring future research. Emerging health profiles indicate that even in very advanced age, quality of life may be improved by enhanced diagnostics and optimal disease management. Mobility limitations may be addressed with preventive efforts.

A Prospective Comparison of Robotic and Laparoscopic Pyeloplasty

PubMed Central

Link, Richard E.; Bhayani, Sam B.; Kavoussi, Louis R.

2006-01-01

Objective: To determine whether robotic-assisted pyeloplasty (RLP) has any significant clinical or cost advantages over laparoscopic pyeloplasty (LP) for surgeons already facile with intracorporeal suturing. Summary Background Data: LP has become an established management approach for primary ureteropelvic junction obstruction. More recently, the da Vinci robot has been applied to this procedure (RLP) in an attempt to shorten the learning curve. Whether RLP provides any significant advantage over LP for the experienced laparoscopist remains unclear. Methods: Ten consecutive cases each of transperitoneal RLP and LP performed by a single surgeon were compared prospectively with respect to surgical times and perioperative outcomes. Cost assessment was performed by sensitivity analysis using a mathematical cost model incorporating operative time, anesthesia fees, consumables, and capital equipment depreciation. Results: The RLP and LP groups had statistically indistinguishable demographics, pathology, and similar perioperative outcomes. Mean operative and total room time for RLP was significantly longer than LP by 19.5 and 39.0 minutes, respectively. RLP was much more costly than LP (2.7 times), due to longer operative time, increased consumables costs, and depreciation of the costly da Vinci system. However, even if depreciation was eliminated, RLP was still 1.7 times as costly as LP. One-way sensitivity analysis showed that LP operative time must increase to almost 6.5 hours for it to become cost equivalent to RLP. Conclusions: For the experienced laparoscopist, application of the da Vinci robot resulted in no significant clinical advantage and added substantial cost to transperitoneal laparoscopic dismembered pyeloplasty. PMID:16552199

Intergenerational Continuity in Maltreatment

PubMed Central

Thornberry, Terence P.; Henry, Kimberly L.

2013-01-01

Identification of the causes of child maltreatment perpetration is prerequisite for developing efficacious prevention initiatives to reduce its occurrence. Earlier maltreatment victimization is often suggested as an important cause of subsequent maltreatment perpetration. This study investigates a) whether maltreatment victimization causes subsequent perpetration and b) whether the timing of maltreatment victimization—childhood versus adolescence—alters this relationship. We use data from the Rochester Youth Development Study, a longitudinal study begun in Rochester, New York in 1988, based on a stratified random sample of 1000 seventh and eighth graders. At the most recent followup, 80% were reinterviewed. Child Protective Services data were collected on substantiated incidents of maltreatment victimization from birth to age 17 and on maltreatment perpetration through average age 33, n = 816. Using propensity score models to control selection effects, we find that a history of maltreatment victimization significantly increases the odds of becoming a perpetrator of maltreatment. Although childhood-limited maltreatment does not significantly increase the odds of maltreatment perpetration, maltreatment that occurs in adolescence or that begins in childhood and persists into adolescence does. Adolescent maltreatment was found to be more serious in terms of type, chronicity, and severity than childhood-limited maltreatment, offering a possible explanation for this finding. Therefore, maltreatment victimization, especially during adolescence, is a likely cause of subsequent perpetration. Clinical services to interrupt the cycle of maltreatment are needed to protect subsequent generations from experiencing maltreatment and from experiencing the health-risking behaviors that often flow from maltreatment. PMID:23192742

Experimental winter warming modifies thermal performance and primes acorn ants for warm weather.

PubMed

MacLean, Heidi J; Penick, Clint A; Dunn, Robert R; Diamond, Sarah E

2017-07-01

The frequency of warm winter days is increasing under global climate change, but how organisms respond to warmer winters is not well understood. Most studies focus on growing season responses to warming. Locomotor performance is often highly sensitive to temperature, and can determine fitness outcomes through a variety of mechanisms including resource acquisition and predator escape. As a consequence, locomotor performance, and its impacts on fitness, may be strongly affected by winter warming in winter-active species. Here we use the acorn ant, Temnothorax curvispinosus, to explore how thermal performance (temperature-driven plasticity) in running speed is influenced by experimental winter warming of 3-5°C above ambient in a field setting. We used running speed as a measure of performance as it is a common locomotor trait that influences acquisition of nest sites and food in acorn ants. Experimental winter warming significantly altered thermal performance for running speed at high (26 and 36°C) but not low test temperatures (6 and 16°C). Although we saw little differentiation in thermal performance at cooler test temperatures, we saw a marked increase in running speed at the hotter test temperatures for ants that experienced warmer winters compared with those that experienced cooler winters. Our results provide evidence that overwintering temperatures can substantially influence organismal performance, and suggest that we cannot ignore overwintering effects when forecasting organismal responses to environmental changes in temperature. Copyright © 2017 Elsevier Ltd. All rights reserved.

A prospective comparison of robotic and laparoscopic pyeloplasty.

PubMed

Link, Richard E; Bhayani, Sam B; Kavoussi, Louis R

2006-04-01

To determine whether robotic-assisted pyeloplasty (RLP) has any significant clinical or cost advantages over laparoscopic pyeloplasty (LP) for surgeons already facile with intracorporeal suturing. LP has become an established management approach for primary ureteropelvic junction obstruction. More recently, the da Vinci robot has been applied to this procedure (RLP) in an attempt to shorten the learning curve. Whether RLP provides any significant advantage over LP for the experienced laparoscopist remains unclear. Ten consecutive cases each of transperitoneal RLP and LP performed by a single surgeon were compared prospectively with respect to surgical times and perioperative outcomes. Cost assessment was performed by sensitivity analysis using a mathematical cost model incorporating operative time, anesthesia fees, consumables, and capital equipment depreciation. The RLP and LP groups had statistically indistinguishable demographics, pathology, and similar perioperative outcomes. Mean operative and total room time for RLP was significantly longer than LP by 19.5 and 39.0 minutes, respectively. RLP was much more costly than LP (2.7 times), due to longer operative time, increased consumables costs, and depreciation of the costly da Vinci system. However, even if depreciation was eliminated, RLP was still 1.7 times as costly as LP. One-way sensitivity analysis showed that LP operative time must increase to almost 6.5 hours for it to become cost equivalent to RLP. For the experienced laparoscopist, application of the da Vinci robot resulted in no significant clinical advantage and added substantial cost to transperitoneal laparoscopic dismembered pyeloplasty.

Shifting Patterns of the HIV Epidemic in Southwest China: A Case Study Based on Sentinel Surveillance, 1995-2012.

PubMed

Chow, Eric P F; Gao, Liangmin; Chen, Liang; Jing, Jun; Zhang, Lei

2015-06-01

The HIV epidemic is experiencing a rapid shift in transmission profile in China. This study aims to examine the changes in magnitude, transmission pattern, and trend of the HIV epidemic in a typical Southwest Chinese prefecture over the period of 1995-2012. HIV surveillance data from the web-based reporting system were analyzed during this period. We investigated the temporal trends in the changing characteristics of HIV transmission, the HIV disease burden in key affected populations, and assessed the impacts on HIV disease progression due to scale-up of antiretroviral treatment. A total of 3556 HIV/AIDS cases were reported in Yuxi prefecture, Yunnan, over the study period. The number of HIV tests conducted has dramatically increased from 1041 in 1995 to 247,859 in 2012, resulting in a substantial increase in HIV diagnoses from 11 cases to 327 cases over the same period. Since 2005, cumulatively 1250 eligible people living with HIV (PLHIV) have received combination antiretroviral therapy which reduced AIDS disease progression from 9.0% (95% CI: 6.7-11.4%) in 1995 to 0.1% (0-0.3%) in 2012 (ptrend=0.0002). The primary mode of HIV transmission has been shifted from injection sharing (71.9% diagnoses in 1995-2004) to unsafe sexual contacts (82.6% diagnoses in 2012). Yuxi prefecture is experiencing a concentrated but shifting HIV epidemic. Scale-up of HIV testing is essential to effective sentinel surveillance and enhancing early diagnosis and treatment in PLHIV.

Epidemiology of obesity in the Western Hemisphere.

PubMed

Ford, Earl S; Mokdad, Ali H

2008-11-01

Obesity has emerged as a global public health challenge. The objective of this review was to examine epidemiological aspects of obesity in the Western Hemisphere. Using PubMed, we searched for publications about obesity (prevalence, trends, correlates, economic costs) in countries in North America, Central America, South America, and the Caribbean. To the extent possible, we focused on studies that were primarily population based in design and on four countries in the Western Hemisphere: Brazil, Canada, Mexico, and the United States. Data compiled by the International Obesity Task Force show a substantial level of obesity in all of or selected areas of the Bahamas, Barbados, Canada, Chile, Guyana, Mexico, Panama, Paraguay, Peru, St. Lucia, Trinidad and Tobago, the United States, and Venezuela. Furthermore, countries such as Brazil, Canada, Mexico, and the United States have experienced increases in the prevalence of obesity. In many countries, the prevalence of obesity is higher among women than men and in urban areas than in rural areas. The relationship between socioeconomic status and obesity depends on the stage of economic transition. Early in the transition, the prevalence of obesity is positively related to income whereas at some point during the transition the prevalence becomes inversely related to income. Like other countries in the Western Hemisphere, the four countries that we focused on have experienced a rising tide of obesity. The high and increasing prevalence of obesity and its attendant comorbidities are likely to pose a serious challenge to the public health and medical care systems in these countries.

Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis.

PubMed

Nathan, Steven D; Albera, Carlo; Bradford, Williamson Z; Costabel, Ulrich; du Bois, Roland M; Fagan, Elizabeth A; Fishman, Robert S; Glaspole, Ian; Glassberg, Marilyn K; Glasscock, Kenneth F; King, Talmadge E; Lancaster, Lisa; Lederer, David J; Lin, Zhengning; Pereira, Carlos A; Swigris, Jeffrey J; Valeyre, Dominique; Noble, Paul W; Wells, Athol U

2016-05-01

The assessment of treatment response in idiopathic pulmonary fibrosis (IPF) is complicated by the variable clinical course. We examined the variability in the rate of disease progression and evaluated the effect of continued treatment with pirfenidone in patients who experienced meaningful progression during treatment. The source population included patients enrolled in the ASCEND and CAPACITY trials (N=1247). Pearson's correlation coefficients were used to characterise the relationship between changes in FVC during consecutive 6-month intervals in the placebo population. Outcomes following a ≥10% decline in FVC were evaluated by comparing the proportion of patients in the pirfenidone and placebo groups who experienced a ≥10% decline in FVC or death during the subsequent 6 months. A weak negative correlation was observed between FVC changes during consecutive intervals in the placebo population (coefficient, -0.146, p<0.001), indicating substantial variability. Thirty-four (5.5%) and 68 (10.9%) patients in the pirfenidone and placebo groups, respectively, experienced a ≥10% decline in FVC by month 6. During the subsequent 6 months, fewer patients in the pirfenidone group compared with placebo experienced a ≥10% decline in FVC or death (5.9% vs 27.9%; relative difference, 78.9%). There was one (2.9%) death in the pirfenidone group and 14 (20.6%) deaths in the placebo group (relative difference, 85.7%). Longitudinal FVC data from patients with IPF showed substantial intrasubject variability, underscoring the inability to reliably assess therapeutic response using serial FVC trends. In patients who progressed during treatment, continued treatment with pirfenidone resulted in a lower risk of subsequent FVC decline or death. NCT01366209, NCT00287729, NCT00287716. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis

PubMed Central

Nathan, Steven D; Albera, Carlo; Bradford, Williamson Z; Costabel, Ulrich; du Bois, Roland M; Fagan, Elizabeth A; Fishman, Robert S; Glaspole, Ian; Glassberg, Marilyn K; King, Talmadge E; Lancaster, Lisa; Lederer, David J; Lin, Zhengning; Pereira, Carlos A; Swigris, Jeffrey J; Valeyre, Dominique; Noble, Paul W; Wells, Athol U

2016-01-01

Background The assessment of treatment response in idiopathic pulmonary fibrosis (IPF) is complicated by the variable clinical course. We examined the variability in the rate of disease progression and evaluated the effect of continued treatment with pirfenidone in patients who experienced meaningful progression during treatment. Methods The source population included patients enrolled in the ASCEND and CAPACITY trials (N=1247). Pearson's correlation coefficients were used to characterise the relationship between changes in FVC during consecutive 6-month intervals in the placebo population. Outcomes following a ≥10% decline in FVC were evaluated by comparing the proportion of patients in the pirfenidone and placebo groups who experienced a ≥10% decline in FVC or death during the subsequent 6 months. Results A weak negative correlation was observed between FVC changes during consecutive intervals in the placebo population (coefficient, −0.146, p<0.001), indicating substantial variability. Thirty-four (5.5%) and 68 (10.9%) patients in the pirfenidone and placebo groups, respectively, experienced a ≥10% decline in FVC by month 6. During the subsequent 6 months, fewer patients in the pirfenidone group compared with placebo experienced a ≥10% decline in FVC or death (5.9% vs 27.9%; relative difference, 78.9%). There was one (2.9%) death in the pirfenidone group and 14 (20.6%) deaths in the placebo group (relative difference, 85.7%). Conclusions Longitudinal FVC data from patients with IPF showed substantial intrasubject variability, underscoring the inability to reliably assess therapeutic response using serial FVC trends. In patients who progressed during treatment, continued treatment with pirfenidone resulted in a lower risk of subsequent FVC decline or death. Trial registration numbers NCT01366209, NCT00287729, NCT00287716. PMID:26968970

Prevalence of and risk factors for sexual victimization in college women in Chile.

PubMed

Lehrer, Jocelyn A; Lehrer, Vivian L; Lehrer, Evelyn L; Oyarzún, Pamela B

2007-12-01

To date, no quantitative studies have examined the prevalence or correlates of sexual violence among college students in Chile. An anonymous survey with questions on gender-based violence, demographic and socioeconomic characteristics, and childhood experiences with violence was administered to students at a major public university in Santiago. Descriptive statistics were generated to determine the prevalence and context of sexual victimization experienced by female students, and ordered logit models were used to identify associated risk factors. Nine percent of subjects reported that the most severe form of undesired sexual contact they had experienced since age 14 was rape; 6% indicated attempted rape and 16% another form of sexual victimization. Seventeen percent of subjects reported having experienced some form of undesired sexual contact in the past 12 months alone. Alcohol or other drugs had been used in most cases of rape or attempted rape, by the victim (6%), the perpetrator (9%) or both (56%). In four sequential models, factors associated with increased odds of victimization included low parental education (Model 1) and childhood sexual abuse (Models 3 and 4); the association between witnessing domestic violence and victimization attained marginal significance (Model 2). Attending religious services during adolescence was associated with reduced odds of victimization (Models 1 and 2). Childhood sexual abuse was the only factor associated with victimization when all variables were included. A substantial proportion of young women in the sample reported experiences of rape, attempted rape or other forms of forced sexual contact, indicating a need for further attention to this public health problem in Chile.

Gender, Stress in Childhood and Adulthood, and Trajectories of Change in Body Mass

PubMed Central

Liu, Hui; Umberson, Debra

2015-01-01

Despite substantial evidence of the linkage between stress and weight change, previous studies have not considered how stress trajectories that begin in childhood and fluctuate throughout adulthood may work together to have long-term consequences for weight change. Working from a stress and life course perspective, we investigate the linkages between childhood stress, adulthood stress and trajectories of change in body mass (i.e., Body Mass Index, BMI) over time, with attention to possible gender variation in these processes. Data are drawn from a national longitudinal survey of the Americans’ Changing Lives (N=3,617). Results from growth curve analyses suggest that both women and men who experienced higher levels of childhood stress also report higher levels of stress in adulthood. At the beginning of the study period, higher levels of adulthood stress are related to greater BMI for women but not men. Moreover, women who experienced higher levels of childhood stress gained weight more rapidly throughout the 15-year study period than did women who experienced less childhood stress, but neither childhood nor adulthood stress significantly modified men’s BMI trajectories. These findings add to our understanding of how childhood stress—a more important driver of long-term BMI increase than adult stress—reverberates throughout the life course to foster cumulative disadvantage in body mass, and how such processes differ for men and women. Results highlight the importance of considering sex-specific social contexts of early childhood in order to design effective clinical programs that prevent or treat overweight and obesity later in life. PMID:26151391

The proprietary hospital industry: a financial analysis 1972-1982.

PubMed

Michel, A; Shaked, I; Daley, J

1985-01-01

This paper evaluates the performance of both specific firms within the American for-profit hospital industry and the industry as a whole. First, traditional financial analysis is used to evaluate individual publicly traded for-profit chains. Then, industry performance from 1973 to 1982 is evaluated using a set of measures based on Modern Portfolio Theory. The traditional financial analysis indicates that the industry seems increasingly profitable as well as increasingly healthy from the perspective of utilizing its assets and reducing its collection period. However, the industry's rapid growth rate has strained its ability to use additional debt funding and has created a potentially dangerous liquidity position. Measures based on Modern Portfolio Theory indicate that the average return of the industry has improved over the past 5 years. However, its risk has also increased. Nevertheless, the increase in risk is more than offset by the increased average return. In addition, recent legislation designed 'to reward the efficient' has introduced a significant degree of uncertainty into the industry's performance for the coming years. Thus, hospitals' ability to maintain the substantial profitability and rate of growth they have experienced over the past decade will depend on how well they will adapt to the changing environment.

Evaluation of Technologies to Prevent Precipitation During Water Recovery from Urine

NASA Technical Reports Server (NTRS)

Broyan, James L., Jr.; Pickering, Karen D.; Adam, Niklas M.; Mitchell, Julie L.; Anderson, Molly S.; Carter, Layne; Muirhead, Dean; Gazda, Daniel B.

2011-01-01

The International Space Station (ISS) Urine Processor Assembly (UPA) experienced a hardware failure in the Distillation Assembly (DA) in October 2010. Initially the UPA was operated to recover 85% of the water from urine through distillation, concentrating the contaminants in the remaining urine. The DA failed due to precipitation of calcium sulfate (gypsum) which caused a loss of UPA function. The ISS UPA operations have been modified to only recover 70% of the water minimizing gypsum precipitation risk but substantially increasing water resupply needs. This paper describes the feasibility assessment of several technologies (ion exchange, chelating agents, threshold inhibitors, and Lorentz devices) to prevent gypsum precipitation. The feasibility assessment includes the development of assessment methods, chemical modeling, bench top testing, and validation testing in a flight-like ground UPA unit. Ion exchange technology has been successfully demonstrated and has been recommended for further development. The incorporation of the selected technology will enable water recovery to be increased from 70% back to the original 85% and improve the ISS water balance.

Population level differences in thermal sensitivity of energy assimilation in terrestrial salamanders.

PubMed

Clay, Timothy A; Gifford, Matthew E

2017-02-01

Thermal adaptation predicts that thermal sensitivity of physiological traits should be optimized to thermal conditions most frequently experienced. Furthermore, thermodynamic constraints predict that species with higher thermal optima should have higher performance maxima and narrower performance breadths. We tested these predictions by examining the thermal sensitivity of energy assimilation between populations within two species of terrestrial-lungless salamanders, Plethodon albagula and P. montanus. Within P. albagula, we examined populations that were latitudinally separated by >450km. Within P. montanus, we examined populations that were elevationally separated by >900m. Thermal sensitivity of energy assimilation varied substantially between populations of P. albagula separated latitudinally, but did not vary between populations of P. montanus separated elevationally. Specifically, in P. albagula, the lower latitude population had a higher thermal optimum, higher maximal performance, and narrower performance breadth compared to the higher latitude population. Furthermore, across all individuals as thermal optima increased, performance maxima also increased, providing support for the theory that "hotter is better". Copyright © 2016 Elsevier Ltd. All rights reserved.

The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding.

PubMed

Winkler, U H

2001-12-01

To investigate whether medical treatment with tranexamic acid would increase the quality of life of women with heavy menstrual bleeding. This open, uncontrolled usage study included 849 women diagnosed with heavy menstrual bleeding and considered eligible for tranexamic-acid treatment. The condition of the women was investigated at baseline and after the first and the third treated menstruation. Quality of life and subjectively experienced state of health were assessed with the aid of a questionnaire. Satisfaction with the treatment was registered. After the third menstruation, 80% of the women were satisfied with the treatment. Impairment of social activities and impairment at work were greatly reduced by the treatment. Substantial improvements were also recorded with regard to alertness, productivity, cleanliness, spirits, action radius and overall well-being. Adverse reactions to the drug used for the treatment were few and non-serious. Medical treatment with tranexamic acid increases quality of life for women with heavy menstrual bleeding.

Advanced Glycation End Products: Link between Diet and Ovulatory Dysfunction in PCOS?

PubMed

Garg, Deepika; Merhi, Zaher

2015-12-04

PCOS is the most common cause of anovulation in reproductive-aged women with 70% experiencing ovulatory problems. Advanced glycation end products are highly reactive molecules that are formed by non-enzymatic reactions of sugars with proteins, nucleic acids and lipids. AGEs are also present in a variety of diet where substantial increase in AGEs can result due to thermal processing and modifications of food. Elevation in bodily AGEs, produced endogenously or absorbed exogenously from high-AGE diets, is further exaggerated in women with PCOS and is associated with ovulatory dysfunction. Additionally, increased expression of AGEs as pro-inflammatory receptors in the ovarian tissue has been observed in women with PCOS. In this review, we summarize the role of dietary AGEs as mediators of metabolic and reproductive alterations in PCOS. Once a mechanistic understanding of the relationship between AGEs and anovulation is established, there is a promise that such knowledge will contribute to the subsequent development of targeted pharmacological therapies that will treat anovulation and improve ovarian health in women with PCOS.

Climate-driven extinctions shape the phylogenetic structure of temperate tree floras.

PubMed

Eiserhardt, Wolf L; Borchsenius, Finn; Plum, Christoffer M; Ordonez, Alejandro; Svenning, Jens-Christian

2015-03-01

When taxa go extinct, unique evolutionary history is lost. If extinction is selective, and the intrinsic vulnerabilities of taxa show phylogenetic signal, more evolutionary history may be lost than expected under random extinction. Under what conditions this occurs is insufficiently known. We show that late Cenozoic climate change induced phylogenetically selective regional extinction of northern temperate trees because of phylogenetic signal in cold tolerance, leading to significantly and substantially larger than random losses of phylogenetic diversity (PD). The surviving floras in regions that experienced stronger extinction are phylogenetically more clustered, indicating that non-random losses of PD are of increasing concern with increasing extinction severity. Using simulations, we show that a simple threshold model of survival given a physiological trait with phylogenetic signal reproduces our findings. Our results send a strong warning that we may expect future assemblages to be phylogenetically and possibly functionally depauperate if anthropogenic climate change affects taxa similarly. © 2015 John Wiley & Sons Ltd/CNRS.

Delinquent-oriented attitudes mediate the relation between parental inconsistent discipline and early adolescent behavior.

PubMed

Halgunseth, Linda C; Perkins, Daniel F; Lippold, Melissa A; Nix, Robert L

2013-04-01

Although substantial research supports the association between parental inconsistent discipline and early adolescent behaviors, less is understood on mechanisms underlying this relation. This study examined the mediating influence of delinquent-oriented attitudes in early adolescence. Using a longitudinal sample of 324 rural adolescents and their parents, findings revealed that inconsistent discipline in sixth grade predicted an increase in adolescent delinquent-oriented attitudes by seventh grade which, in turn, predicted both an increase in early adolescent antisocial behaviors and a decrease in socially competent behaviors by eighth grade. Therefore, it appears that accepting attitudes toward delinquency may in part develop from experiencing inconsistent discipline at home and may offer a possible explanation as to why early adolescents later engage in more antisocial and less socially competent behaviors. Findings may inform family-based preventive intervention programs that seek to decrease behavior problems and promote social competence in early adolescents. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

Alternative careers in the geosciences

NASA Astrophysics Data System (ADS)

Fiske, Peter S.; Smith, Guy M.

The Earth sciences continue to produce substantial numbers of Ph.D.s. However, many subdisciplines of solid-Earth geophysics are experiencing a lack of growth, or an actual contraction, in the number of permanent positions available in traditional academia, government, and industry settings. The alternative of indefinite-term soft money positions is growing increasingly scarce as research funds continue to get tighter. Furthermore, even those in permanent research positions are finding it harder and harder to obtain funding for their projects.The relative scarcity of traditional permanent employment and the continuing changes in the research funding environment cause an increasing number of Ph.D.-trained geoscientists to explore the possibility of employment outside the traditional geophysical research areas. Unfortunately, information about “nontraditional” career paths is hard to come by. For the most part, Ph.D. programs are designed to prepare students for the research job market only. Those who have chosen other options usually no longer attend scientific meetings and thus are not able to communicate their experience to others contemplating a similar departure.

Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis.

PubMed

Webster, Joshua D; Michalowski, Aleksandra M; Dwyer, Jennifer E; Corps, Kara N; Wei, Bih-Rong; Juopperi, Tarja; Hoover, Shelley B; Simpson, R Mark

2012-01-01

The extent to which histopathology pattern recognition image analysis (PRIA) agrees with microscopic assessment has not been established. Thus, a commercial PRIA platform was evaluated in two applications using whole-slide images. Substantial agreement, lacking significant constant or proportional errors, between PRIA and manual morphometric image segmentation was obtained for pulmonary metastatic cancer areas (Passing/Bablok regression). Bland-Altman analysis indicated heteroscedastic measurements and tendency toward increasing variance with increasing tumor burden, but no significant trend in mean bias. The average between-methods percent tumor content difference was -0.64. Analysis of between-methods measurement differences relative to the percent tumor magnitude revealed that method disagreement had an impact primarily in the smallest measurements (tumor burden <3%). Regression-based 95% limits of agreement indicated substantial agreement for method interchangeability. Repeated measures revealed concordance correlation of >0.988, indicating high reproducibility for both methods, yet PRIA reproducibility was superior (C.V.: PRIA = 7.4, manual = 17.1). Evaluation of PRIA on morphologically complex teratomas led to diagnostic agreement with pathologist assessments of pluripotency on subsets of teratomas. Accommodation of the diversity of teratoma histologic features frequently resulted in detrimental trade-offs, increasing PRIA error elsewhere in images. PRIA error was nonrandom and influenced by variations in histomorphology. File-size limitations encountered while training algorithms and consequences of spectral image processing dominance contributed to diagnostic inaccuracies experienced for some teratomas. PRIA appeared better suited for tissues with limited phenotypic diversity. Technical improvements may enhance diagnostic agreement, and consistent pathologist input will benefit further development and application of PRIA.

Seasonal Daphnia biomass in winterkill and nonwinterkill glacial lakes of South Dakota

USGS Publications Warehouse

Isermann, D.A.; Chipps, S.R.; Brown, M.L.

2004-01-01

We compared the seasonal biomass (??g dry weight/L) and body size of Daphnia pulex populations between South Dakota lakes that experienced nearly complete winterkill (n = 2) and those that did not experience fish winterkill the previous winter (n = 2). In spring (March-May), D. pulex biomass was substantially lower in winterkill lakes (0.4-1.9 ??g/L) than in nonwinterkill lakes (13.8-129.4 ??g/L). In summer months (June-July), D. pulex biomass increased in all lakes but was generally higher in winterkill lakes (332.1-469. 3 ??g/L) than in nonwinterkill lakes (88.6-204.2 ??g/L). By September, D. pulex biomass was substantially higher in winterkill lakes (243.8 ??g/L) than in nonwinterkill lakes (1.0 ??g/L). The mean size of D. pulex increased significantly from March to August in winterkill lakes but not in nonwinterkill lakes. The seasonal differences in D. pulex biomass and size may have been related to size-selective predation by planktivorous fishes because the ratio of spine length to body length in D. pulex was significantly lower in winterkill lakes (mean, 0.34) than in nonwinterkill lakes (mean, 0.43). Moreover, seasonal patterns in chlorophyll-a biomass were inversely related to D. pulex biomass. The production and subsequent hatching of resting eggs may be important for recolonization of Daphnia populations after severe winter conditions. The survival and growth of zooplanktivorous fish that are stocked to repopulate winterkill lakes may be increased by delaying stocking until Daphnia populations recover from severe winterkill.

Race/ethnicity and workplace discrimination: results of a national survey of physicians.

PubMed

Nunez-Smith, Marcella; Pilgrim, Nanlesta; Wynia, Matthew; Desai, Mayur M; Jones, Beth A; Bright, Cedric; Krumholz, Harlan M; Bradley, Elizabeth H

2009-11-01

Promoting racial/ethnic diversity within the physician workforce is a national priority. However, the extent of racial/ethnic discrimination reported by physicians from diverse backgrounds in today's health-care workplace is unknown. To determine the prevalence of physician experiences of perceived racial/ethnic discrimination at work and to explore physician views about race and discussions regarding race/ethnicity in the workplace. Cross-sectional, national survey conducted in 2006-2007. Practicing physicians (total n = 529) from diverse racial/ethnic backgrounds in the United States. We examined physicians' experience of racial/ethnic discrimination over their career course, their experience of discrimination in their current work setting, and their views about race/ethnicity and discrimination at work. The proportion of physicians who reported that they had experienced racial/ethnic discrimination "sometimes, often, or very often" during their medical career was substantial among non-majority physicians (71% of black physicians, 45% of Asian physicians, 63% of "other" race physicians, and 27% of Hispanic/Latino(a) physicians, compared with 7% of white physicians, all p < 0.05). Similarly, the proportion of non-majority physicians who reported that they experienced discrimination in their current work setting was substantial (59% of black, 39% of Asian, 35% of "other" race, 24% of Hispanic/Latino(a) physicians, and 21% of white physicians). Physician views about the role of race/ethnicity at work varied significantly by respondent race/ethnicity. Many non-majority physicians report experiencing racial/ethnic discrimination in the workplace. Opportunities exist for health-care organizations and diverse physicians to work together to improve the climate of perceived discrimination where they work.

Fire Effects on Greenhouse Gas Emissions from Wetlands in the Yukon-Kuskokwim Delta, Alaska

NASA Astrophysics Data System (ADS)

Peter, D. L.; Bristol, E. M.; Mann, P. J.; Schade, J. D.; Natali, S.; Holmes, R. M.

2017-12-01

Climate change in increasing both fire frequency and fire intensity, especially in Arctic regions. Fire often leads to increased soil temperature, which increases the likelihood of permafrost thaw. Permafrost soils in northern latitudes store large amounts of carbon, and thawing of this permafrost will alter carbon cycling processes, which may substantially impact ecosystem processes in aquatic ecosystems. One potential consequence of altered aquatic ecosystem processes is changes in carbon emissions resulting from altered carbon inputs from thawing permafrost. Aquatic ecosystems are known to be hotspots of greenhouse gas emissions, so changes in greenhouse gas fluxes from them may have important impacts on global climate. In this work, we focused on CO2 and CH4 fluxes from peat plateau ponds, fens and bogs in the Yukon-Kuskokwim (YK) Delta in southwest Alaska. The YK Delta experienced unprecedented fires in summer 2015, presenting an opportunity to assess the impacts of fire on greenhouse gas fluxes from aquatic ecosystems. We sampled upland ponds, channel fens, bogs, and lowland ponds in sites that had burned in 2015 as well as from similar sites where there have been no recorded fires in the past 75 years. We found little difference in gas flux between aquatic sites in burned and unburned sites, with the exception of channel fens, which showed substantially higher fluxes of both CH4 and CO2 in burned sites. This is in contrast to similar measurements taken in summer 2016, when burned ponds showed consistently higher GHG fluxes, suggesting these increases were not sustained in sites other than channel fens. These results, if general, indicate the possibility that the response of aquatic ecosystems to fire may lead to positive feedbacks on climate change.

A Nation of Immigrants: Assimilation and Economic Outcomes in the Age of Mass Migration

PubMed Central

Abramitzky, Ran; Boustan, Leah Platt; Eriksson, Katherine

2015-01-01

During the Age of Mass Migration (1850–1913), the United States maintained an open border, absorbing 30 million European immigrants. Prior cross-sectional work finds that immigrants initially held lower-paid occupations than natives but converged over time. In newly assembled panel data, we show that, in fact, the average immigrant did not face a substantial occupation-based earnings penalty upon first arrival and experienced occupational advancement at the same rate as natives. Cross-sectional patterns are driven by biases from declining arrival cohort skill level and departures of negatively selected return migrants. We show that assimilation patterns vary substantially across sending countries and persist in the second generation. PMID:26609186

Assessing societal vulnerability of U.S. Pacific Northwest communities to storm-induced coastal change

USGS Publications Warehouse

Baron, Heather M.; Wood, Nathan J.; Ruggerio, Peter; Allan, Jonathan; Corcoran, Patrick

2010-01-01

Progressive increases in storm intensities and extreme wave heights have been documented along the U.S. West Coast. Paired with global sea level rise and the potential for an increase in El Niño occurrences, these trends have substantial implications for the vulnerability of coastal communities to natural coastal hazards. Community vulnerability to hazards is characterized by the exposure, sensitivity, and adaptive capacity of human-environmental systems that influence potential impacts. To demonstrate how societal vulnerability to coastal hazards varies with both physical and social factors, we compared community exposure and sensitivity to storm-induced coastal change scenarios in Tillamook (Oregon) and Pacific (Washington) Counties. While both are backed by low-lying coastal dunes, communities in these two counties have experienced different shoreline change histories and have chosen to use the adjacent land in different ways. Therefore, community vulnerability varies significantly between the two counties. Identifying the reasons for this variability can help land-use managers make decisions to increase community resilience and reduce vulnerability in spite of a changing climate.

Phenotypic vulnerability of energy balance responses to sleep loss in healthy adults

PubMed Central

Spaeth, Andrea M.; Dinges, David F.; Goel, Namni

2015-01-01

Short sleep duration is a risk factor for increased hunger and caloric intake, late-night eating, attenuated fat loss when dieting, and for weight gain and obesity. It is unknown whether altered energy-balance responses to sleep loss are stable (phenotypic) over time, and the extent to which individuals differ in vulnerability to such responses. Healthy adults experienced two laboratory exposures to sleep restriction separated by 60–2132 days. Caloric intake, meal timing and weight were objectively measured. Although there were substantial phenotypic differences among participants in weight gain, increased caloric intake, and late-night eating and fat intake, responses within participants showed stability across sleep restriction exposures. Weight change was consistent in both normal-weight and overweight adults. Weight change and increased caloric intake were more stable in men whereas late-night eating was consistent in both genders. This is the first evidence of phenotypic differential vulnerability and trait-like stability of energy balance responses to repeated sleep restriction, underscoring the need for biomarkers and countermeasures to predict and mitigate this vulnerability. PMID:26446681

Elkhorn Slough: Detecting Eutrophication through Geospatial Modeling Applications

NASA Astrophysics Data System (ADS)

Caraballo Álvarez, I. O.; Childs, A.; Jurich, K.

2016-12-01

Elkhorn Slough in Monterey, California, has experienced substantial nutrient loading and eutrophication over the past 21 years as a result of fertilizer-rich runoff from nearby agricultural fields. This study seeks to identify and track spatial patterns of eutrophication hotspots and the correlation to land use changes, possible nutrient sources, and general climatic trends using remotely sensed and in situ data. Threats of rising sea level, subsiding marshes, and increased eutrophication hotspots demonstrate the necessity to analyze the effects of increasing nutrient loads, relative sea level changes, and sedimentation within Elkhorn Slough. The Soil & Water Assessment Tool (SWAT) model integrates specified inputs to assess nutrient and sediment loading and their sources. TerrSet's Land Change Modeler forecasts the future potential of land change transitions for various land cover classes around the slough as a result of nutrient loading, eutrophication, and increased sedimentation. TerrSet's Earth Trends Modeler provides a comprehensive analysis of image time series to rapidly assess long term eutrophication trends and detect spatial patterns of known hotspots. Results from this study will inform future coastal management practices and provide greater spatial and temporal insight into Elkhorn Slough eutrophication dynamics.

Phenotypic vulnerability of energy balance responses to sleep loss in healthy adults.

PubMed

Spaeth, Andrea M; Dinges, David F; Goel, Namni

2015-10-08

Short sleep duration is a risk factor for increased hunger and caloric intake, late-night eating, attenuated fat loss when dieting, and for weight gain and obesity. It is unknown whether altered energy-balance responses to sleep loss are stable (phenotypic) over time, and the extent to which individuals differ in vulnerability to such responses. Healthy adults experienced two laboratory exposures to sleep restriction separated by 60-2132 days. Caloric intake, meal timing and weight were objectively measured. Although there were substantial phenotypic differences among participants in weight gain, increased caloric intake, and late-night eating and fat intake, responses within participants showed stability across sleep restriction exposures. Weight change was consistent in both normal-weight and overweight adults. Weight change and increased caloric intake were more stable in men whereas late-night eating was consistent in both genders. This is the first evidence of phenotypic differential vulnerability and trait-like stability of energy balance responses to repeated sleep restriction, underscoring the need for biomarkers and countermeasures to predict and mitigate this vulnerability.

Impact of urban sprawl on water quality in eastern Massachusetts, USA.

PubMed

Tu, Jun; Xia, Zong-Guo; Clarke, Keith C; Frei, Allan

2007-08-01

A study of water quality, land use, and population variations over the past three decades was conducted in eastern Massachusetts to examine the impact of urban sprawl on water quality using geographic information system and statistical analyses. Since 1970, eastern Massachusetts has experienced pronounced urban sprawl, which has a substantial impact on water quality. High spatial correlations are found between water quality indicators (especially specific conductance, dissolved ions, including Ca, Mg, Na, and Cl, and dissolved solid) and urban sprawl indicators. Urbanized watersheds with high population density, high percentage of developed land use, and low per capita developed land use tended to have high concentrations of water pollutants. The impact of urban sprawl also shows clear spatial difference between suburban areas and central cities: The central cities experienced lower increases over time in specific conductance concentration, compared to suburban and rural areas. The impact of urban sprawl on water quality is attributed to the combined effects of population and land-use change. Per capita developed land use is a very important indicator for studying the impact of urban sprawl and improving land use and watershed management, because inclusion of this indicator can better explain the temporal and spatial variations of more water quality parameters than using individual land use or/and population density.

A day at a time: caregiving on the edge in advanced COPD

PubMed Central

Simpson, A Catherine; Young, Joanne; Donahue, Margaret; Rocker, Graeme

2010-01-01

The human cost of advanced chronic obstructive pulmonary disease (COPD) for informal caregivers in Canada is mostly unknown. Formal care is episodic, and informal caregivers provide the bulk of care between exacerbations. While patients fear becoming burdensome to family, we lack relevant data against which to assess the validity of this fear. The purpose of our qualitative study was to better understand the extent and nature of ‘burden’ experienced by informal caregivers in advanced COPD. The analysis of 14 informal caregivers interviews yielded the global theme ‘a day at a time,’ reflecting caregivers’ approach to the process of adjusting/coping. Subthemes were: loss of intimate relationship/identity, disease-related demands, and coping-related factors. Caregivers experiencing most distress described greater negative impact on relational dynamics and identity, effects they associated with increasing illness demands especially care recipients’ difficult, emotionally controlling attitudes/behaviors. Our findings reflect substantial caregiver vulnerability in terms of an imbalance between burden and coping capacity. Informal caregivers provide necessary, cost-effective care for those living with COPD and/or other chronic illness. Improved understanding of the physical, emotional, spiritual, and relational factors contributing to their vulnerability can inform new chronic care models better able to support their efforts. PMID:20631814

Feeling close and doing well: the prevalence and motivational effects of interpersonally engaging emotions in Mexican and European American cultural contexts.

PubMed

Savani, Krishna; Alvarez, Ayme; Mesquita, Batja; Markus, Hazel Rose

2013-01-01

Two studies investigate whether interpersonally engaging emotions--those that bring the self closer to others (e.g., affection, shame)--are central to the model of self and relationships prevalent in Mexican cultural contexts. Study 1 demonstrated that compared to people in European American contexts, people in Mexican contexts were more likely to report experiencing interpersonally engaging emotions and less likely to report experiencing interpersonally disengaging emotions. Study 2 found that interpersonally engaging emotions had a substantial influence on performance motivation in Mexican contexts--Mexican participants solved more word search puzzles after recalling instances in which they experienced positive interpersonally engaging emotions, and fewer after recalling negative interpersonally disengaging emotions; in contrast, there were no differences by condition for European Americans. These findings significantly extend previous research by documenting the implications of relational concerns (e.g., simpatia, personalismo) for emotion and motivation in Mexican contexts, and are the first to demonstrate the motivational effects of interpersonally engaging emotions.

Battered pets and domestic violence: animal abuse reported by women experiencing intimate violence and by nonabused women.

PubMed

Ascione, Frank R; Weber, Claudia V; Thompson, Teresa M; Heath, John; Maruyama, Mika; Hayashi, Kentaro

2007-04-01

Women residing at domestic violence shelters (S group) were nearly 11 times more likely to report that their partner had hurt or killed pets than a comparison group of women who said they had not experienced intimate violence (NS group). Reports of threatened harm to pets were more than 4 times higher for the S group. Using the Conflict Tactics Scale, the authors demonstrated that severe physical violence was a significant predictor of pet abuse. The vast majority of shelter women described being emotionally close to their pets and distraught by the abuse family pets experienced. Children were often exposed to pet abuse, and most reported being distressed by these experiences. A substantial minority of S-group women reported that their concern for their pets' welfare prevented them from seeking shelter sooner. This seemed truer for women without children, who may have had stronger pet attachments. This obstacle to seeking safety should be addressed by domestic violence agencies.

Improvement in racial disparities in years of life lost in the USA since 1990.

PubMed

Buchanich, Jeanine M; Doerfler, Shannon M; Lann, Michael F; Marsh, Gary M; Burke, Donald S

2018-01-01

To examine changes in cause-specific Years of Life Lost (YLL) by age, race, and sex group in the USA from 1990 to 2014. 60 million death reports from the National Center for Health Statistics (NCHS) were categorized by age group, sex, race, and cause of death. YLL were calculated using age-specific life expectancies. Age groups were: infants <1, children 1-19, adults 20-64, and older adults 65+. Blacks have historically experienced more years of life lost than whites or other racial groups in the USA. In the year 1990 the YLL per 100,000 population was 21,103 for blacks, 14,160 for whites, and 7,417 for others. Between 1990 and 2014 overall YLL in the USA improved by 10%, but with marked variations in the rate of change across age, race, and sex groups. Blacks (all ages, both sexes) showed substantial improvement with a 28% reduction in YLL, compared to whites (all ages, both sexes) who showed a 4% reduction. Among blacks, improvements were seen in all age groups: reductions of 43%, 48%, 28%, and 25% among infants, children, adults, and older adults, respectively. Among whites, reductions of 33%, 44%, and 18% were seen in infants, children, and older adults, but there was a 6% increase in YLL among white adults. YLL increased by 18% in white adult females and declined 1% in white adult males. American Indian/Alaska Native women also had worsening in YLL, with an 8% increase. Asian Pacific Islanders consistently had the lowest YLL across all ages. Whites had a higher proportion of YLL due to overdose; blacks had a higher proportion due to homicide at younger ages and to heart disease at older ages. Race-based disparities in YLL in the USA since 1990 have narrowed considerably, largely as a result of improvements among blacks compared to whites. Adult white and American Indian / Alaskan Native females have experienced worsening YLL, while white males have experienced essentially no change. If recent trajectories continue, adult black/white disparities in YLL will continue to narrow.

Faculty perceptions of gender discrimination and sexual harassment in academic medicine.

PubMed

Carr, P L; Ash, A S; Friedman, R H; Szalacha, L; Barnett, R C; Palepu, A; Moskowitz, M M

2000-06-06

Gender-based discrimination and sexual harassment are common in medical practice and may be even more prevalent in academic medicine. To examine the prevalence of gender-based discrimination and sexual harassment among medical school faculty and the associations of gender-based discrimination with number of publications, career satisfaction, and perceptions of career advancement. A self-administered mailed questionnaire of U.S. medical school faculty that covered a broad range of topics relating to academic life. 24 randomly selected medical schools in the contiguous United States. A random sample of 3332 full-time faculty, stratified by specialty, graduation cohort, and sex. Prevalence of self-reported experiences of discrimination and harassment, number of peer-reviewed publications, career satisfaction, and perception of career advancement. Female faculty were more than 2.5 times more likely than male faculty to perceive gender-based discrimination in the academic environment (P < 0.001). Among women, rates of reported discrimination ranged from 47% for the youngest faculty to 70% for the oldest faculty. Women who reported experiencing negative gender bias had similar productivity but lower career satisfaction scores than did other women (P< 0.001). About half of female faculty but few male faculty experienced some form of sexual harassment. These experiences were similarly prevalent across the institutions in the sample and in all regions of the United States. Female faculty who reported being sexually harassed perceived gender-specific bias in the academic environment more often than did other women (80% compared with 61 %) and more often reported experiencing gender bias in professional advancement (72% compared with 47%). Publications, career satisfaction, and professional confidence were not affected by sexual harassment, and self-assessed career advancement was only marginally lower for female faculty who had experienced sexual harassment (P = 0.06). Despite substantial increases in the number of female faculty, reports of gender-based discrimination and sexual harassment remain common.

"Regressed Experts" as a New State in Teachers' Professional Development: Lessons from Computer Science Teachers' Adjustments to Substantial Changes in the Curriculum

ERIC Educational Resources Information Center

Liberman, Neomi; Kolikant, Yifat Ben-David; Beeri, Catriel

2012-01-01

Due to a program reform in Israel, experienced CS high-school teachers faced the need to master and teach a new programming paradigm. This situation served as an opportunity to explore the relationship between teachers' content knowledge (CK) and their pedagogical content knowledge (PCK). This article focuses on three case studies, with emphasis…

CVX Damage Control Information Technology Evolutionary Model

DTIC Science & Technology

1999-03-01

technology -based learning generally) may be exciting technically, it does not automatically lead to better educational programs. Good instructional design...expected to act on the first Aircraft Carrier to attempt substantial manning reductions if nothing is learned from Smart Ship. Beyond the technologies ... technology of the day. Many of the lessons learned then are in use today. However, technology breakthroughs we are now experiencing invite us to

Ethnic and gender specific life expectancies of the Singapore population, 1965 to 2009 – converging, or diverging?

PubMed Central

2013-01-01

Background The increase in life expectancy and the persistence of expectancy gaps between different social groups in the 20th century are well-described in Western developed countries, but less well documented in the newly industrialised countries of Asia. Singapore, a multiethnic island-state, has undergone a demographic and epidemiologic transition concomitant with economic development. We evaluate secular trends and differences in life expectancy by ethnicity and gender in Singapore, from independence to the present. Methods Period abridged life tables were constructed to derive the life expectancy of the Singapore population from 1965 to 2009 using data from the Department of Statistics and the Registry of Births and Deaths, Singapore. Results All 3 of Singapore’s main ethnic groups, and both genders, experienced an increase in life expectancy at birth and at 65 years from 1965 to 2009, though at substantially different rates. Although there has been a convergence in life expectancy between Indians and Chinese, the (substantial) gap between Malays and the other two ethnic groups has remained. Females continued to have a higher life expectancy at birth and at 65 years than males throughout this period, with no evidence of convergence. Conclusions Ethnic and gender differences in life expectancy persist in Singapore despite its rapid economic development. Targeted chronic disease prevention measures and health promotion activities focusing on people of Malay ethnicity and the male community may be needed to remedy this inequality. PMID:24160733

Do vehicle grants and vehicle adaptations grants promote transport mobility and community access for children with disabilities in Sweden?

PubMed

Sjödin, Linda; Buchanan, Angus; Mundt, Beate; Karlsson, Emelie; Falkmer, Torbjörn

2012-02-01

A vast majority of the journeys made by children with disabilities in Sweden are in the family car, which usually is bought and adapted for the child with governmental subsidies. Despite the important philosophical views about accessible vehicles, little is known about the impact of vehicle adaptations on families' lives. The aim of the study was to investigate parent views about the impact of vehicle grants and vehicle adaptation grants on their children's transport mobility and community access. In total, 434 parents of children with disabilities in Sweden who had received vehicle grants and/or vehicle adaptation grants between 1998-2007 responded to a questionnaire comprising questions with both pre-selected and open-ended answers. A non-responder analysis was performed. Children with disabilities were found to increase their transport mobility and community access in society as vehicle grants and/or vehicle adaptation grants were given to their parents. Their travel patterns and their travel priorities with their family car indicated that family friends and relatives and leisure activities were frequently visited and prioritised destinations. The grants were linked to access to social and family activities, provided environmental gains and led to increased experienced security. The results also showed that the potential to make spontaneous trips had increased substantially and that families experienced feelings of freedom and enhanced community access. The non-responder analysis confirmed these results. According to parents, vehicle grants and vehicle adaptation grants for children with disabilities have a positive impact on the children's transport mobility and community access. © 2011 The Authors. Australian Occupational Therapy Journal © 2011 Occupational Therapy Australia.

Loss of ecosystem productivity with repeated drought: a multi-year experiment to assess the role of drought legacy effects

NASA Astrophysics Data System (ADS)

Smith, M. D.; Knapp, A.; Hoover, D. L.; Avolio, M. L.; Felton, A. J.; Slette, I.; Wilcox, K.

2017-12-01

Climate extremes, such as drought, are increasing in frequency and intensity, and the ecological consequences of these extreme events can be substantial and widespread. Yet, little is known about the factors that determine recovery of ecosystem function post-drought. Such knowledge is particularly important because post-drought recovery periods can be protracted depending on drought legacy effects (e.g., loss key plant populations, altered community structure and/or biogeochemical processes). These drought legacies may alter ecosystem function for many years post-drought and may impact future sensitivity to climate extremes. With forecasts of more frequent drought, there is an imperative to understand whether and how post-drought legacies will affect ecosystem response to future drought events. To address this knowledge gap, we experimentally imposed over an eight year period two extreme growing season droughts, each two years in duration followed by a two-year recovery period, in a central US grassland. We found that aboveground net primary productivity (ANPP) declined dramatically with the first drought and was accompanied by a large shift in plant species composition (loss of C3 forb and increase in C4 grasses). This drought legacy - shift in plant composition - persisted two years post-drought. Yet, despite this legacy, ANPP recovered fully. However, we expected that previously-droughted grassland would be less sensitive to a second extreme drought due to the shift in plant composition. Contrary to this expectation, previously droughted grassland experienced a greater loss in ANPP than grassland that had not experienced drought. Furthermore, previously droughted grassland did not fully recover after the second drought. Thus, the legacy of drought - a shift in plant community composition - increased ecosystem sensitivity to a future extreme drought event.

Risks from Worldwide Terrorism: Mortality and Morbidity Patterns and Trends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bogen, K T; Jones, E D

Worldwide data on terrorist incidents between 1968 and 2004 gathered by the RAND corporation and the Oklahoma City National Memorial Institute for the Prevention of Terrorism (MIPT) were assessed for patterns and trends in morbidity/mortality. The data involve a total of 19,828 events, 7,401 ''adverse'' events (each causing {ge}1 victim), 91,346 cases of casualty (either injury or death) and 25,408 deaths. Analyses revealed a number of interesting patterns and apparently significant trends. Most terror-related adverse events, casualties and deaths involved bombs and guns. Weapon-specific patterns and terror-related risk levels in Israel (ISR) have differed markedly from those of all othermore » regions combined (AOR). ISR had a fatal fraction of casualties about half that of AOR, but has experienced relatively constant lifetime terror-related casualty risks on the order of 0.5%--a level 2 to 3 orders of magnitude more than those experienced in AOR, which have increased {approx}100-fold over the same period. Individual event fatality has increased steadily, the median increasing from 14 to 50%. Lorenz curves obtained indicate substantial dispersion among victim/event rates: about half of all victims were caused by the top 2% (10%) of harm-ranked events in OAR (ISR). Extreme values of victim/event rates were found to be well modeled by classic or generalized Pareto distributions, indicating that these rates have been as predictable as similarly extreme phenomena such as rainfall, sea levels, earthquakes, etc. This observation suggests that these extreme-value patterns may be used to improve strategies to prevent and manage risks associated with terror-related consequences.« less

An investigation of the interactive effects of the capability for suicide and acute agitation on suicidality in a military sample.

PubMed

Ribeiro, Jessica D; Bender, Theodore W; Buchman, Jennifer M; Nock, Matthew K; Rudd, M David; Bryan, Craig J; Lim, Ingrid C; Baker, Monty T; Knight, Chadwick; Gutierrez, Peter M; Joiner, Thomas E

2015-01-01

According to the interpersonal theory of suicide (1, 2), the difficulties inherently associated with death by suicide deter many individuals from engaging in suicidal behavior. Consistent with the notion that suicide is fearsome, acute states of heightened arousal are commonly observed in individuals immediately prior to lethal and near-lethal suicidal behavior. We suggest that among individuals who possess elevated levels of the capability for suicide, the heightened state of arousal experienced during periods of acute agitation may facilitate suicidal behavior in part because it would provide the necessary energy to approach a potentially lethal stimulus. Among individuals who are low on capability, the arousal experienced during agitation may result in further avoidance. In the present project we examine how acute agitation may interact with the capability for suicide to predict suicidality in a large military sample (n = 1,208) using hierarchical multiple regression. Results were in line with a priori hypotheses: among individuals high on capability, as agitation increases, suicidality increases whereas as agitation increases among individuals low on capability, suicidality decreases. Results held beyond the effects of thwarted belongingness, perceived burdensomeness, and suicidal cognitions. Beyond further substantiating the link between agitation and suicide, findings of the present study provide evidence for the construct validity of the acquired capability as well as offer initial evidence for moderating role of capability on the effect of agitation on suicide. Limitations of the current study highlight a need for future research that improves upon the techniques used in the present study. Implications for science and practice are discussed. © 2014 Wiley Periodicals, Inc.

Hippocampal neural correlates for values of experienced events.

PubMed

Lee, Hyunjung; Ghim, Jeong-Wook; Kim, Hoseok; Lee, Daeyeol; Jung, MinWhan

2012-10-24

Newly experienced events are often remembered together with how rewarding the experiences are personally. Although the hippocampus is a candidate structure where subjective values are integrated with other elements of episodic memory, it is uncertain whether and how the hippocampus processes value-related information. We examined how activity of dorsal CA1 and dorsal subicular neurons in rats performing a dynamic foraging task was related to reward values that were estimated using a reinforcement learning model. CA1 neurons carried significant signals related to action values before the animal revealed its choice behaviorally, indicating that the information on the expected values of potential choice outcomes was available in CA1. Moreover, after the outcome of the animal's goal choice was revealed, CA1 neurons carried robust signals for the value of chosen action and they temporally overlapped with the signals related to the animal's goal choice and its outcome, indicating that all the signals necessary to evaluate the outcome of an experienced event converged in CA1. On the other hand, value-related signals were substantially weaker in the subiculum. These results suggest a major role of CA1 in adding values to experienced events during episodic memory encoding. Given that CA1 neuronal activity is modulated by diverse attributes of an experienced event, CA1 might be a place where all the elements of episodic memory are integrated.

Long-term growth of Ginkgo with CO(2) enrichment increases leaf ice nucleation temperatures and limits recovery of the photosynthetic system from freezing.

PubMed

Terry, A C; Quick, W P; Beerling, D J

2000-09-01

The importance of subzero temperature interactions with elevated CO(2) on plant carbon metabolism has received rather little attention, despite their likely role in influencing future vegetation productivity and dynamics. Here we focused on the critical issues of CO(2)-enrichment effects on leaf-freezing temperatures, subsequent membrane damage, and recovery of the photosynthetic system. We show that growth in elevated CO(2) (70 Pa) results in a substantial and significant (P<0.01) increase (up to 4 degrees C) in the ice nucleation temperature of leaves of Maidenhair tree (Ginkgo biloba), which was observed consistently throughout the 1999 growing season relative to their ambient CO(2) (35 Pa) counterparts. We suggest that increased sensitivity of leaves to ice damage after growth in elevated CO(2) provides an explanation for increased photoinhibition observed in the field early and late in the growing season when low nighttime temperatures are experienced. This new mechanism is proposed in addition to the earlier postulated explanation for this phenomenon involving a reduction in the rate of triose-P utilization owing to a decrease in the rate of carbohydrate export from the leaf.

Long-Term Growth of Ginkgo with CO2 Enrichment Increases Leaf Ice Nucleation Temperatures and Limits Recovery of the Photosynthetic System from Freezing1

PubMed Central

Terry, Andrew C.; Quick, W. Paul; Beerling, David J.

2000-01-01

The importance of subzero temperature interactions with elevated CO2 on plant carbon metabolism has received rather little attention, despite their likely role in influencing future vegetation productivity and dynamics. Here we focused on the critical issues of CO2-enrichment effects on leaf-freezing temperatures, subsequent membrane damage, and recovery of the photosynthetic system. We show that growth in elevated CO2 (70 Pa) results in a substantial and significant (P < 0.01) increase (up to 4°C) in the ice nucleation temperature of leaves of Maidenhair tree (Ginkgo biloba), which was observed consistently throughout the 1999 growing season relative to their ambient CO2 (35 Pa) counterparts. We suggest that increased sensitivity of leaves to ice damage after growth in elevated CO2 provides an explanation for increased photoinhibition observed in the field early and late in the growing season when low nighttime temperatures are experienced. This new mechanism is proposed in addition to the earlier postulated explanation for this phenomenon involving a reduction in the rate of triose-P utilization owing to a decrease in the rate of carbohydrate export from the leaf. PMID:10982433

Increased congenital heart defects in children born to women with systemic lupus erythematosus: results from the offspring of Systemic Lupus Erythematosus Mothers Registry Study.

PubMed

Vinet, Évelyne; Pineau, Christian A; Scott, Susan; Clarke, Ann E; Platt, Robert W; Bernatsky, Sasha

2015-01-13

In a large population-based study, we aimed to determine whether children born to women with systemic lupus erythematosus (SLE) have an increased risk of congenital heart defects (CHDs) in comparison with children born to women without SLE. The Offspring of SLE Mothers Registry (OSLER) includes all women who had ≥1 hospitalization for delivery after SLE diagnosis, identified through Quebec's healthcare databases (1989-2009), and a randomly selected control group of women, matched ≥4:1 for age and year of delivery. We identified children born live to SLE mothers and their matched controls, and ascertained CHD based on ≥1 hospitalization or physician visit with relevant diagnostic codes, within the first 12 months of life. We performed multivariable logistic regression analyses, using the generalized estimating equation method, to adjust for relevant covariates. Five hundred nine women with SLE had 719 children, whereas 5824 matched controls had 8493 children. In comparison with controls, children born to women with SLE experienced more CHD (5.2% [95% confidence interval (CI), 3.7-7.1] versus 1.9% [95% CI, 1.6-2.2], difference 3.3% [95% CI, 1.9-5.2]). In multivariable analyses, children born to women with SLE had a substantially increased risk of CHD (odds ratio, 2.62; 95% CI, 1.77-3.88) in comparison with controls. In addition, in comparison with controls, offspring of SLE mothers had a substantially increased risk of having a CHD repair procedure (odds ratio, 5.82; 95% CI, 1.77-19.09). In comparison with children from the general population, children born to women with SLE have an increased risk of CHD, and an increased risk of having a CHD repair procedure, as well. © 2014 American Heart Association, Inc.

Assessing dental caries prevalence in African-American youth and adults.

PubMed

Seibert, Wilda; Farmer-Dixon, Cherae; Bolden, Theodore E; Stewart, James H

2004-01-01

It has been well documented that dental caries affect millions of children in the USA with the majority experiencing decay by the late teens. This is especially true for low-income minorities. The objective of this descriptive study was to determine dental caries prevalence in a sample of low-income African-American youth and adults. A total of 1034 individuals were examined. They were divided into two age groups: youth, 9-19 years and adults, 20-39 years. Females comprised approximately 65 percent (64.5) of the study group. The DMFT Index was used to determine caries prevalence in this study population. The DMFT findings showed that approximately 73 percent (72.9 percent) of the youth had either decayed, missing or filled teeth. Male youth had slightly higher DMFT mean scores than female youth: male mean = 7.93, standard error = 0.77, female mean = 7.52, standard error = 0.36; however, as females reached adulthood their DMFT scores increased substantially, mean = 15.18, standard error = 0.36. Caries prevalence was much lower in male adults, DMFT, mean = 7.22, standard error of 0.33. The decayed component for female adults mean score was 6.81, a slight increase over adult males, mean = 6.58. Although there were few filled teeth in both age groups, female adults had slightly more filled teeth than male adults, females mean = 2.91 vs. males; however, adult males experienced slightly more missing teeth, mean = 5.62 as compared to adult females, mean = 5.46. n = 2.20. Both female and male adults had an increase in missing teeth. As age increased there was a significant correlation among decayed, missing and filled teeth as tested by Analysis of Variance (ANOVA), p < 0.01. A significant correlation was found between filled teeth by sex, p < .005. We conclude that caries prevalence was higher in female and male youth, but dental caries increased more rapidly in females as they reached adulthood.

Trends in hospital admissions involving suicidal behaviour in the Northern Territory, 2001-2013.

PubMed

Leckning, Bernard A; Li, Shu Qin; Cunningham, Teresa; Guthridge, Steven; Robinson, Gary; Nagel, Tricia; Silburn, Sven

2016-06-01

To investigate trends in hospital admissions involving suicidal behaviour in the Northern Territory (NT) resident population over the period 2001-2013. Estimates of age-standardised rates and average changes in the annual rate of hospital admissions involving suicidal behaviour were calculated by socio-demographic characteristics and types of suicidal behaviour. Overall rates for Indigenous admissions were 2.7 times higher than non-Indigenous admissions and had increased by almost twice as much. While male and female rates of admission were similar for both Indigenous and non-Indigenous residents, the average annual change in rates was greater for Indigenous females (13.4%) compared to males (8.8%) and for non-Indigenous males (7.7%) compared to females (5.2%). Younger and middle-aged Indigenous admissions experienced increasing rates of admissions, whilst trends were similar across age groups for non-Indigenous admissions. Admissions with a diagnosis of suicidal ideation increased the most across all groups. Trends in intentional self-harm admissions differed according to Indigenous status and sex. There have been substantial increases in hospital admissions involving suicidal behaviour in the NT, most markedly for Indigenous residents. Indigenous females and youth appear to be at increasing risk. The steep increase in suicidal ideation across all groups warrants further investigation. © The Royal Australian and New Zealand College of Psychiatrists 2016.

Carbon Nanotube-based Sensor and Method for Continually Sensing Changes in a Structure

NASA Technical Reports Server (NTRS)

Jordan, Jeffry D. (Inventor); Watkins, Anthony Neal (Inventor); Oglesby, Donald M. (Inventor); Ingram, JoAnne L. (Inventor)

2007-01-01

A sensor has a plurality of carbon nanotube (CNT)-based conductors operatively positioned on a substrate. The conductors are arranged side-by-side, such as in a substantially parallel relationship to one another. At least one pair of spaced-apart electrodes is coupled to opposing ends of the conductors. A portion of each of the conductors spanning between each pair of electrodes comprises a plurality of carbon nanotubes arranged end-to-end and substantially aligned along an axis. Because a direct correlation exists between resistance of a carbon nanotube and carbon nanotube strain, changes experienced by the portion of the structure to which the sensor is coupled induce a change in electrical properties of the conductors.

Status and trends of adult Lost River (Deltistes luxatus) and shortnose (Chasmistes brevirostris) sucker populations in Upper Klamath Lake, Oregon, 2014

USGS Publications Warehouse

Hewitt, David A.; Janney, Eric C.; Hayes, Brian S.; Harris, Alta C.

2015-10-02

Despite relatively high survival in most years, we conclude that both species have experienced substantial decreases in the abundance of spawning adults because losses from mortality have not been balanced by recruitment of new individuals. Although capture-recapture data indicate substantial recruitment of new individuals into the spawning populations for SNS and river spawning LRS in some years, size data do not corroborate these estimates. As a result, the status of the endangered sucker populations in Upper Klamath Lake remains worrisome, especially for shortnose suckers. Our monitoring program provides a robust platform for estimating vital population parameters, evaluating the status of the populations, and assessing the effectiveness of conservation and recovery efforts.

Delayed responses of an Arctic ecosystem to an extremely dry summer: impacts on net ecosystem exchange and vegetation functioning

NASA Astrophysics Data System (ADS)

Zona, D.; Lipson, D. A.; Richards, J. H.; Phoenix, G. K.; Liljedahl, A. K.; Ueyama, M.; Sturtevant, C. S.; Oechel, W. C.

2013-12-01

The importance and mode of action of extreme events on the global carbon budget are inadequately understood. This includes the differential impact of extreme events on various ecosystem components, lag effects, recovery times, and compensatory processes. Summer 2007 in Barrow, Arctic Alaska, experienced unusually high air temperatures (fifth warmest over a 65 yr period) and record low precipitation (lowest over a 65 yr period). These abnormal conditions resulted in strongly reduced net Sphagnum CO2 uptake, but no effect neither on vascular plant development nor on net ecosystem exchange (NEE) from this arctic tundra ecosystem. Gross primary production (GPP) and ecosystem respiration (Reco) were both generally greater during most of this extreme summer. Cumulative ecosystem C uptake in 2007 was similar to the previous summers, showing the capacity of the ecosystem to compensate in its net ecosystem exchange (NEE) despite the impact on other functions and structure such as substantial necrosis of the Sphagnum layer. Surprisingly, the lowest ecosystem C uptake (2005-2009) was observed during the 2008 summer, i.e the year directly following the extremely summer. In 2008, cumulative C uptake was ∼70% lower than prior years. This reduction cannot solely be attributed to mosses, which typically contribute with ∼40% - of the entire ecosystem C uptake. The minimum summer cumulative C uptake in 2008 suggests that the entire ecosystem experienced difficulty readjusting to more typical weather after experiencing exceptionally warm and dry conditions. Importantly, the return to a substantial cumulative C uptake occurred two summers after the extreme event, which suggest a high resilience of this tundra ecosystem. Overall, these results show a highly complex response of the C uptake and its sub-components to atypically dry conditions. The impact of multiple extreme events still awaits further investigation.

Differences between Dual Users and Switchers Center around Vaping Behavior and Its Experiences Rather than Beliefs and Attitudes

PubMed Central

2017-01-01

(1) Background: Many smokers completely switch to vaping (switchers), whereas others use e-cigarettes (e-cigs) alongside tobacco cigarettes (dual users). To the extent that dual users substantially lower the number of cigarettes, they will reduce health risks from smoking. However, from a medical point of view, exclusive vaping is preferable to dual use; (2) Methods: Using an online questionnaire we assessed behavioral, cognitive and attitudinal aspects of e-cig use in smoking and ex-smoking vapers; (3) Results: Our sample consisted of 19% dual users and 81% switchers. Before e-cig initiation, both groups smoked on average 22 cigarettes per day (CPD). After e-cig initiation, dual users decreased tobacco consumption by 82% and were low-to-moderately cigarette dependent. Both groups had been vaping for on average 22 months, were highly e-cig dependent, used state-of-the-art e-cigs, nicotine concentrations of 4–8 mg/mL and often flavors other than tobacco. Dual users used substantially less e-liquid per week than switchers but reported a similar number of puffs/day, experienced less e-cig efficacy, more practical problems, more negative and less positive consequences, and endorsed smoking reduction (rather than quitting) as a more important reason to start vaping. For both groups, e-cig risk perception was low and little stigmatization was experienced. Dual users preferred tobacco cigarettes in stressful situations and when rapid nicotine uptake is required. E-cigs were preferred where cigarettes are prohibited and to reduce second-hand smoke; (4) Conclusions: Differences between dual users and switchers center around variables proximal to the vaping behavior and its experienced effects rather than hinging on more general vaping-related beliefs and attitudes. PMID:29295483

Differences between Dual Users and Switchers Center around Vaping Behavior and Its Experiences Rather than Beliefs and Attitudes.

PubMed

Adriaens, Karolien; Van Gucht, Dinska; Baeyens, Frank

2017-12-23

(1) Background: Many smokers completely switch to vaping (switchers), whereas others use e-cigarettes (e-cigs) alongside tobacco cigarettes (dual users). To the extent that dual users substantially lower the number of cigarettes, they will reduce health risks from smoking. However, from a medical point of view, exclusive vaping is preferable to dual use; (2) Methods: Using an online questionnaire we assessed behavioral, cognitive and attitudinal aspects of e-cig use in smoking and ex-smoking vapers; (3) Results: Our sample consisted of 19% dual users and 81% switchers. Before e-cig initiation, both groups smoked on average 22 cigarettes per day (CPD). After e-cig initiation, dual users decreased tobacco consumption by 82% and were low-to-moderately cigarette dependent. Both groups had been vaping for on average 22 months, were highly e-cig dependent, used state-of-the-art e-cigs, nicotine concentrations of 4-8 mg/mL and often flavors other than tobacco. Dual users used substantially less e-liquid per week than switchers but reported a similar number of puffs/day, experienced less e-cig efficacy, more practical problems, more negative and less positive consequences, and endorsed smoking reduction (rather than quitting) as a more important reason to start vaping. For both groups, e-cig risk perception was low and little stigmatization was experienced. Dual users preferred tobacco cigarettes in stressful situations and when rapid nicotine uptake is required. E-cigs were preferred where cigarettes are prohibited and to reduce second-hand smoke; (4) Conclusions: Differences between dual users and switchers center around variables proximal to the vaping behavior and its experienced effects rather than hinging on more general vaping-related beliefs and attitudes.

Utah Report of Participation in Part B Subpart 2 of the Education Professions Development Act (Title V of Higher Education Act of 1965). Phase I.

ERIC Educational Resources Information Center

Utah State Board of Education, Salt Lake City.

This document contains seven reports on the first phase of EPDA programs in Utah which were intended to train people from the community to make a substantial contribution to the classroom. Carbon County School District provided a program for 19 teacher aides which included college courses and assignment to experienced classroom teachers. The…

Marijuana smoking and reduced pressure in human eyes: drug action or epiphenomenon?

PubMed

Flom, M C; Adams, A J; Jones, R T

1975-01-01

Normal pressure within the human eye was reduced after smoking a socially relevant dose of marijuana (12 mg. delta9-9-tetrahydrocannabinol), but only for light to moderate users who experienced a substantial "high" and a state of peaceful relaxation from the experimental dose. Analysis suggests an indirect effect of the drug associated with relaxation-a psychophysiologic state that can be produced by drug and nondrug means.

Implications of a Resurgent Russian Federation for U.S. European Command

DTIC Science & Technology

2011-06-10

Slovakia, Hungary, Romania , and Moldova. It also has a substantial coastline along the Black Sea. A map of Ukraine is located in Appendix A. Seventy...and is currently experiencing its longest run of sovereign independence.95 Ukraine declared independence from the Russian Empire in 1918 following...after until 1991 from Moscow and St. Petersburg. Georgia gained independence briefly in 1918 following the Russian Revolution and established a

Population Size, Growth, and Environmental Justice Near Oil and Gas Wells in Colorado.

PubMed

McKenzie, Lisa M; Allshouse, William B; Burke, Troy; Blair, Benjamin D; Adgate, John L

2016-11-01

We evaluated population size and factors influencing environmental justice near oil and gas (O&G) wells. We mapped nearest O&G well to residential properties to evaluate population size, temporal relationships between housing and O&G development, and 2012 housing market value distributions in three major Colorado O&G basins. We reviewed land use, building, real estate, and state O&G regulations to evaluate distributive and participatory justice. We found that by 2012 at least 378,000 Coloradans lived within 1 mile of an active O&G well, and this population was growing at a faster rate than the overall population. In the Denver Julesburg and San Juan basins, which experienced substantial O&G development prior to 2000, we observed a larger proportion of lower value homes within 500 feet of an O&G well and that most O&G wells predated houses. In the Piceance Basin, which had not experienced substantial prior O&G development, we observed a larger proportion of high value homes within 500 feet of an O&G well and that most houses predated O&G wells. We observed economic, rural, participatory, and/or distributive injustices that could contribute to health risk vulnerabilities in populations near O&G wells. We encourage policy makers to consider measures to reduce these injustices.

Incubation under climate warming affects learning ability and survival in hatchling lizards.

PubMed

Dayananda, Buddhi; Webb, Jonathan K

2017-03-01

Despite compelling evidence for substantial individual differences in cognitive performance, it is unclear whether cognitive ability influences fitness of wild animals. In many animals, environmental stressors experienced in utero can produce substantial variation in the cognitive abilities of offspring. In reptiles, incubation temperatures experienced by embryos can influence hatchling brain function and learning ability. Under climate warming, the eggs of some lizard species may experience higher temperatures, which could affect the cognitive abilities of hatchlings. Whether such changes in cognitive abilities influence the survival of hatchlings is unknown. To determine whether incubation-induced changes in spatial learning ability affect hatchling survival, we incubated velvet gecko, Amalosia lesueurii , eggs using two fluctuating temperature regimes to mimic current (cold) versus future (hot) nest temperatures. We measured the spatial learning ability of hatchlings from each treatment, and released individually marked animals at two field sites in southeastern Australia. Hatchlings from hot-incubated eggs were slower learners than hatchlings from cold-incubated eggs. Survival analyses revealed that hatchlings with higher learning scores had higher survival than hatchlings with poor learning scores. Our results show that incubation temperature affects spatial learning ability in hatchling lizards, and that such changes can influence the survival of hatchlings in the wild. © 2017 The Author(s).

Youth Suicide: A Cross-Cultural Perspective.

ERIC Educational Resources Information Center

Lester, David

1988-01-01

Examined changes in the suicide rate of teenagers and young adults internationally from 1970 to 1980. Twenty-three nations experienced increases (with Norway experiencing the largest percentage increase), while six experienced decreases. Unlike general suicide rates, teenage suicide rates were not related to the quality of life in the nations…

Determinants of the reliability of ultrasound tomography sound speed estimates as a surrogate for volumetric breast density

PubMed Central

Khodr, Zeina G.; Sak, Mark A.; Pfeiffer, Ruth M.; Duric, Nebojsa; Littrup, Peter; Bey-Knight, Lisa; Ali, Haythem; Vallieres, Patricia; Sherman, Mark E.; Gierach, Gretchen L.

2015-01-01

Purpose: High breast density, as measured by mammography, is associated with increased breast cancer risk, but standard methods of assessment have limitations including 2D representation of breast tissue, distortion due to breast compression, and use of ionizing radiation. Ultrasound tomography (UST) is a novel imaging method that averts these limitations and uses sound speed measures rather than x-ray imaging to estimate breast density. The authors evaluated the reproducibility of measures of speed of sound and changes in this parameter using UST. Methods: One experienced and five newly trained raters measured sound speed in serial UST scans for 22 women (two scans per person) to assess inter-rater reliability. Intrarater reliability was assessed for four raters. A random effects model was used to calculate the percent variation in sound speed and change in sound speed attributable to subject, scan, rater, and repeat reads. The authors estimated the intraclass correlation coefficients (ICCs) for these measures based on data from the authors’ experienced rater. Results: Median (range) time between baseline and follow-up UST scans was five (1–13) months. Contributions of factors to sound speed variance were differences between subjects (86.0%), baseline versus follow-up scans (7.5%), inter-rater evaluations (1.1%), and intrarater reproducibility (∼0%). When evaluating change in sound speed between scans, 2.7% and ∼0% of variation were attributed to inter- and intrarater variation, respectively. For the experienced rater’s repeat reads, agreement for sound speed was excellent (ICC = 93.4%) and for change in sound speed substantial (ICC = 70.4%), indicating very good reproducibility of these measures. Conclusions: UST provided highly reproducible sound speed measurements, which reflect breast density, suggesting that UST has utility in sensitively assessing change in density. PMID:26429241

Determinants of the reliability of ultrasound tomography sound speed estimates as a surrogate for volumetric breast density

DOE Office of Scientific and Technical Information (OSTI.GOV)

Khodr, Zeina G.; Pfeiffer, Ruth M.; Gierach, Gretchen L., E-mail: GierachG@mail.nih.gov

Purpose: High breast density, as measured by mammography, is associated with increased breast cancer risk, but standard methods of assessment have limitations including 2D representation of breast tissue, distortion due to breast compression, and use of ionizing radiation. Ultrasound tomography (UST) is a novel imaging method that averts these limitations and uses sound speed measures rather than x-ray imaging to estimate breast density. The authors evaluated the reproducibility of measures of speed of sound and changes in this parameter using UST. Methods: One experienced and five newly trained raters measured sound speed in serial UST scans for 22 women (twomore » scans per person) to assess inter-rater reliability. Intrarater reliability was assessed for four raters. A random effects model was used to calculate the percent variation in sound speed and change in sound speed attributable to subject, scan, rater, and repeat reads. The authors estimated the intraclass correlation coefficients (ICCs) for these measures based on data from the authors’ experienced rater. Results: Median (range) time between baseline and follow-up UST scans was five (1–13) months. Contributions of factors to sound speed variance were differences between subjects (86.0%), baseline versus follow-up scans (7.5%), inter-rater evaluations (1.1%), and intrarater reproducibility (∼0%). When evaluating change in sound speed between scans, 2.7% and ∼0% of variation were attributed to inter- and intrarater variation, respectively. For the experienced rater’s repeat reads, agreement for sound speed was excellent (ICC = 93.4%) and for change in sound speed substantial (ICC = 70.4%), indicating very good reproducibility of these measures. Conclusions: UST provided highly reproducible sound speed measurements, which reflect breast density, suggesting that UST has utility in sensitively assessing change in density.« less

Cost-effectiveness of Newer Antiretroviral Drugs in Treatment-Experienced Patients with Multi-drug Resistant HIV Disease

PubMed Central

Bayoumi, Ahmed M.; Barnett, Paul G.; Joyce, Vilija R.; Griffin, Susan C.; Sun, Huiying; Bansback, Nick J.; Holodniy, Mark; Sanders, Gillian; Brown, Sheldon T.; Kyriakides, Tassos C.; Angus, Brian; Cameron, D. William; Anis, Aslam H.; Sculpher, Mark; Owens, Douglas K.

2014-01-01

Objective Newer antiretroviral drugs provide substantial benefits but are expensive. We determined the cost-effectiveness of using antiretroviral drugs in combination for patients with multi-drug resistant HIV disease. Design We built a cohort state-transition model representing treatment-experienced patients with low CD4 counts, high viral load levels, and multi-drug resistant virus. We estimated the effectiveness of newer drugs (those approved in 2005 or later) from published randomized trials. We estimated other parameters from a randomized trial and from the literature. The model had a lifetime time horizon and used the perspective of an ideal insurer in the United States. The interventions were combination antiretroviral therapy, consisting of two newer drugs and one conventional drug, compared to three conventional drugs. Outcome measures were life-years, quality-adjusted life-years (QALYs), costs, and incremental cost-effectiveness. Results Substituting newer antiretroviral drugs increased expected survival by 3.9 years in advanced HIV disease. The incremental cost-effectiveness ratio of newer, compared to conventional, antiretroviral drugs was $75,556/QALY gained. Sensitivity analyses showed that substituting only one newer antiretroviral drug cost $54,559 to $68,732/QALY, depending on assumptions about efficacy. Substituting three newer drugs cost $105,956 to $117,477/QALY. Cost-effectiveness ratios were higher if conventional drugs were not discontinued. Conclusions In treatment-experienced patients with advanced HIV disease, use of newer antiretroviral agents can be cost effective, given a cost-effectiveness threshold in the range of $50,000 to $75,000 per QALY gained. Newer antiretroviral agents should be used in carefully selected patients for whom less expensive options are clearly inferior. PMID:24129369

Degradation of benzodiazepines after 120 days of EMS deployment.

PubMed

McMullan, Jason T; Jones, Elizabeth; Barnhart, Bruce; Denninghoff, Kurt; Spaite, Daniel; Zaleski, Erin; Silbergleit, Robert

2014-01-01

EMS treatment of status epilepticus improves outcomes, but the benzodiazepine best suited for EMS use is unclear, given potential high environmental temperature exposures. To describe the degradation of diazepam, lorazepam, and midazolam as a function of temperature exposure and time over 120 days of storage on active EMS units. Study boxes containing vials of diazepam, lorazepam, and midazolam were distributed to 4 active EMS units in each of 2 EMS systems in the southwestern United States during May-August 2011. The boxes logged temperature every minute and were stored in EMS units per local agency policy. Two vials of each drug were removed from each box at 30-day intervals and underwent high-performance liquid chromatography to determine drug concentration. Concentration was analyzed as mean (and 95%CI) percent of initial labeled concentration as a function of time and mean kinetic temperature (MKT). 192 samples were collected (2 samples of each drug from each of 4 units per city at 4 time-points). After 120 days, the mean relative concentration (95%CI) of diazepam was 97.0% (95.7-98.2%) and of midazolam was 99.0% (97.7-100.2%). Lorazepam experienced modest degradation by 60 days (95.6% [91.6-99.5%]) and substantial degradation at 90 days (90.3% [85.2-95.4%]) and 120 days (86.5% [80.7-92.3%]). Mean MKT was 31.6°C (95%CI 27.1-36.1). Increasing MKT was associated with greater degradation of lorazepam, but not midazolam or diazepam. Midazolam and diazepam experienced minimal degradation throughout 120 days of EMS deployment in high-heat environments. Lorazepam experienced significant degradation over 120 days and appeared especially sensitive to higher MKT exposure.

Yolk testosterone and corticosterone in hierarchical follicles and laid eggs of Japanese quail exposed to long-term restraint stress.

PubMed

Okuliarová, Monika; Sárniková, Bozena; Rettenbacher, Sophie; Skrobánek, Peter; Zeman, Michal

2010-01-01

Environmental and behavioural stimuli experienced by egg-laying female birds contribute to intra- and inter-female differences in hormones in the egg yolk with consequences for offspring development. The understanding of physiological mechanisms underlying yolk hormone deposition can aid progress in this field. In our study, we measured the concentration of testosterone and corticosterone in hierarchical follicles and egg yolks of Japanese quail in control and chronic stress conditions. Experimental females were reared under hypodynamia, a model situation for restraint stress, from day 3 to 63 days of age. For yolk hormone analysis, four largest follicles of ovarian hierarchy (F1-F4), eggs present in the oviduct and eggs laid on the day before were collected. In chronically stressed birds, yolk testosterone concentrations decreased from F2 onwards, while yolk corticosterone content was increased from the beginning to the end of egg formation. The follicular profile of hormones suggested testosterone transfer into the yolk directly from granulosa and theca cells, with the highest accumulation during a period 48-72 h before laying the egg. Yolk corticosterone was accumulated from maternal plasma preferentially in early stages of follicular development under control conditions and also in last stages of egg formation under stress conditions. These specific patterns of hormone deposition indicate periods when stimuli experienced by female can substantially modify hormonal content of eggs. Lower testosterone and increased corticosterone yolk concentrations in stressed quail may represent signals mediating information about adverse environmental conditions from the mother to progeny.

Simulation of the effects of different pilot helmets on neck loading during air combat.

PubMed

Mathys, R; Ferguson, S J

2012-09-21

New generation pilot helmets with mounted devices enhance the capabilities of pilots substantially. However, the additional equipment increases the helmet weight and shifts its center of mass forward. Two helmets with different mass properties were modeled to simulate their effects on the pilot's neck. A musculoskeletal computer model was used, with the methods of inverse dynamics and static optimization, to compute the muscle activations and joint reaction forces for a given range of quasi-static postures at various accelerations experienced during air combat. Head postures which induce much higher loads on the cervical spine than encountered in a neutral position could be identified. The increased weight and the forward shift of the center of mass of a new generation helmet lead to higher muscle activations and higher joint reaction loads over a wide range of head and neck movements. The muscle activations required to balance the head and neck in extreme postures increased the compressive force at the T1-C7 level substantially, while in a neutral posture the muscle activations remained low. The lateral neck muscles can reach activations of 100% and cause compressive joint forces up to 1100N during extensive rotations and extensions at high 'vertical' accelerations (Gz). The calculated values have to be interpreted with care as the model has not been validated. Nevertheless, this systematic analysis could separate the effects of head posture, acceleration and helmet mass on neck loading. More reliable data about mass properties and muscle morphometry with a more detailed motion analysis would help to refine the existing model. Copyright © 2012 Elsevier Ltd. All rights reserved.

Exploring Pacific Climate Variability and Its Impacts on East African Water Resources and Food Security

NASA Astrophysics Data System (ADS)

Funk, C. C.; Hoerling, M. P.; Hoell, A.; Liebmann, B.; Verdin, J. P.; Eilerts, G.

2014-12-01

In 8 out the past 15 boreal springs (1999, 2000, 2004, 2008, 2009, 2011, 2012, and 2013), substantial parts of eastern East Africa experienced very low boreal spring rains. These rainfall deficits have triggered widespread food insecurity, and even contributed to the outbreak of famine conditions in Somalia in 2011. At both seasonal and decadal time scales, new science supported by the USAID Famine Early Warning Systems Network seeks to understand the mechanisms producing these droughts. We present research suggesting that the ultimate and proximate causes of these increases in aridity are i) stronger equatorial Pacific SST gradients and ii) associated increases in the strength of the Indo-Pacific Walker circulation. Using observations and new modeling ensembles, we explore the relative contributions of Pacific Decadal Variability (PDV) and global warming under warm and cold east Pacific Ocean states. This question is addressed in two ways: by using atmospheric GCMs forced with full and ENSO-only SSTs, and ii) by decomposing coupled ocean-atmosphere climate simulations into PDV and non-PDV components. These analyses allow us to explore the Walker circulation's sensitivity to climate change under various PDV states, and inform a tentative bracketing of 2030 climate conditions. We conclude by discussing links to East African development. Regions of high rainfall sensitivity are delineated and intersected with recent changes in population and land cover/land use. The interaction of elevation and climate is shown to create climatically secure regions that are likely to remain viable even under drier and warmer conditions; such regions may be logical targets for agricultural intensification. Conversely, arid low elevation regions are likely to experience substantial temperature impacts. Continued expansion into these areas may effectively create more 'drought' even if rainfall increases.

Effects of Nitrogen Fertilization and Thinning Treatments on Subsurface Soil Carbon and Nitrogen

NASA Astrophysics Data System (ADS)

Gross, C. D.; James, J. N.; Harrison, R. B.

2016-12-01

Increases in intensively managed forest plantations have caused concern for the long-term productivity and sustainability of these stands, as decreased organic matter retention and shorter rotations can substantially impact soil nutrition both in the short- and long-term. This study aims to provide data for regional responses of soil carbon (C) and nitrogen (N) by depth to fertilization and thinning treatments. Soil was sampled at an intensively managed Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) plantation in northwestern Oregon, USA. Nine 0.2-ha plots were sampled with at least three pits per plot. Management regimes included no treatment (control), fertilization (F+), minimal thinning (mT), repeated thinning (rT), and combination treatments (mTF+ and rTF+). Fertilized plots received a total of 1120 kg N ha-1 as urea over 16 years. Bulk density and chemical analysis samples were taken in the middle of succeeding soil layers at depths of 0.1, 0.2, 0.5, 1.0, and 1.5 m. Forest floor samples were collected from a randomly placed quadrat. Preliminary results show an increase in total soil C and N of 113 and 106%, respectively, on the mTF+ plot compared to a control plot. The subsoil, defined here as below 0.2 m, contained over 50% of both soil C and N on the mTF+ plot and experienced greater C and N increases than the surface soil following treatment. This study demonstrates that forest management practices over a relatively short time span (<30 years) can significantly alter subsoil, which comprises a substantial portion of biologically available C and N in terrestrial ecosystems. Subsoil processes are critical to our understanding of changes in soil quality and our ability to accurately assess changes in soil C and N reservoirs.

Hypomanic Experience in Young Adults Confers Vulnerability to Intrusive Imagery After Experimental Trauma

PubMed Central

Malik, Aiysha; Goodwin, Guy M.; Hoppitt, Laura

2014-01-01

Emotional mental imagery occurs across anxiety disorders, yet is neglected in bipolar disorder despite high anxiety comorbidity. Furthermore, a heightened susceptibility to developing intrusive mental images of stressful events in bipolar disorder and people vulnerable to it (with hypomanic experience) has been suggested. The current study assessed, prospectively, whether significant hypomanic experience (contrasting groups scoring high vs. low on the Mood Disorder Questionnaire, MDQ) places individuals at increased risk of visual reexperiencing after experimental stress. A total of 110 young adults watched a trauma film and recorded film-related intrusive images for 6 days. Compared to the low MDQ group, the high MDQ group experienced approximately twice as many intrusive images, substantiated by convergent measures. Findings suggest hypomanic experience is associated with developing more frequent intrusive imagery of a stressor. Because mental imagery powerfully affects emotion, such imagery may contribute to bipolar mood instability and offer a cognitive treatment target. PMID:25419498

Regime shifts and resilience in China's coastal ecosystems.

PubMed

Zhang, Ke

2016-02-01

Regime shift often results in large, abrupt, and persistent changes in the provision of ecosystem services and can therefore have significant impacts on human wellbeing. Understanding regime shifts has profound implications for ecosystem recovery and management. China's coastal ecosystems have experienced substantial deterioration within the past decades, at a scale and speed the world has never seen before. Yet, information about this coastal ecosystem change from a dynamics perspective is quite limited. In this review, I synthesize existing information on coastal ecosystem regime shifts in China and discuss their interactions and cascading effects. The accumulation of regime shifts in China's coastal ecosystems suggests that the desired system resilience has been profoundly eroded, increasing the potential of abrupt shifts to undesirable states at a larger scale, especially given multiple escalating pressures. Policy and management strategies need to incorporate resilience approaches in order to cope with future challenges and avoid major losses in China's coastal ecosystem services.

Siple Dome ice reveals two modes of millennial CO2 change during the last ice age

PubMed Central

Ahn, Jinho; Brook, Edward J.

2014-01-01

Reconstruction of atmospheric CO2 during times of past abrupt climate change may help us better understand climate-carbon cycle feedbacks. Previous ice core studies reveal simultaneous increases in atmospheric CO2 and Antarctic temperature during times when Greenland and the northern hemisphere experienced very long, cold stadial conditions during the last ice age. Whether this relationship extends to all of the numerous stadial events in the Greenland ice core record has not been clear. Here we present a high-resolution record of atmospheric CO2 from the Siple Dome ice core, Antarctica for part of the last ice age. We find that CO2 does not significantly change during the short Greenlandic stadial events, implying that the climate system perturbation that produced the short stadials was not strong enough to substantially alter the carbon cycle. PMID:24781344

June 2017: The Earliest European Summer Mega-heatwave of Reanalysis Period

NASA Astrophysics Data System (ADS)

Sánchez-Benítez, A.; García-Herrera, R.; Barriopedro, D.; Sousa, P. M.; Trigo, R. M.

2018-02-01

This paper examines the characteristics of the heatwave that affected western and central Europe in June 2017. Using a novel algorithm, we show that its extension, intensity, and persistence were comparable to those of other European mega-heatwaves, but it occurred earlier in the summer. The most affected area was Iberia, which experienced devastating forest fires with human casualties and the warmest temperatures of the reanalysis period from daily to seasonal scales. The peak of the mega-heatwave displayed an unprecedented warm air intrusion due to a record-breaking subtropical ridge with signatures closer to those of July and August. The atmospheric circulation was the main triggering factor of the event. However, thermodynamical changes of the last decades made a substantial contribution to the event, by increasing the likelihood of surpassing high-temperature thresholds. This episode could be a good example of a coming future, with high-summer mega-heatwaves occurring earlier.

Sales promotion strategies and youth drinking in Australia.

PubMed

Pettigrew, Simone; Biagioni, Nicole; Jones, Sandra C; Daube, Mike; Kirby, Gary; Stafford, Julia; Chikritzhs, Tanya

2015-09-01

This study employed an exploratory approach to generate detailed information about how in-store shopping experiences and exposure to sales promotion activities feature in the alcohol choices of Australian 18-21 year old drinkers. The qualitative methods of interviews, focus groups, and emailed narratives were used during 2014 to collect relevant data. The findings suggest that young drinkers' in-store shopping experiences and exposure to sales promotions influence the type, range, and quantity of alcohol purchased. In particular, the role of sales staff can be critical in increasing the amount of alcohol purchased by drawing drinkers' attention to and encouraging their participation in sales promotions. There thus appears to be an important interaction between promotional practices and young drinkers purchasing substantially larger quantities of alcohol than originally intended. Such practices need review in light of the high risk of alcohol-related harm experienced by many members of this age group. Copyright © 2015 Elsevier Ltd. All rights reserved.

Does inequality erode social trust? Results from multilevel models of US states and counties.

PubMed

Fairbrother, Malcolm; Martin, Isaac W

2013-03-01

Previous research has argued that income inequality reduces people's trust in other people, and that declining social trust in the United States in recent decades has been due to rising levels of income inequality. Using multilevel models fitted to data from the General Social Survey, this paper substantially qualifies these arguments. We show that while people are less trusting in US states with higher income inequality, this association holds only cross-sectionally, not longitudinally; since the 1970s, states experiencing larger increases in inequality have not suffered systematically larger declines in trust. For counties, there is no statistically significant relationship either cross-sectionally or longitudinally. There is therefore only limited empirical support for the argument that inequality influences generalized social trust; and the declining trust of recent decades certainly cannot be attributed to rising inequality. Copyright © 2012 Elsevier Inc. All rights reserved.

Lifelong learning skills: how experienced are students when they enter medical school?

PubMed

Whittle, Sue R; Murdoch-Eaton, Deborah G

2004-09-01

Widening participation initiatives together with changes in school curricula in England may broaden the range of lifelong learning skills experience of new undergraduates. This project examines the experience levels of current students, as a comparative baseline. First-year medical students completed a questionnaire on arrival, investigating their practice of 31 skills during the previous two years. Responses show that most students have regularly practised transferable skills. However, significant numbers report little experience, particularly in IT skills such as email, using the Internet, spreadsheets and databases. Some remain unfamiliar with word processing. Library research, essay writing and oral presentation are also rarely practised by substantial numbers. One-third of students lack experience of evaluating their own strengths and weaknesses. Current students already show diversity of experience in skills on arrival at medical school. Changes in the near future may increase this range of experience further, and necessitate changes to undergraduate courses.

India's growing clinical research sector: opportunity for global companies.

PubMed

Varawalla, Nermeen

2007-06-01

Backed by a compelling foundation of essential requirements necessary for effective clinical trial conduct, and aided by initiatives that address concerns of data quality, regulatory timelines and IP protection, the clinical development sector in India has experienced annual revenue growth rates of 25% in the past two to three years, and is poised to participate substantially in global drug development. As both clinical trial sponsors and CROs increase their research capabilities in India, the clinical development sector is facing challenges with staff resourcing and facilities. Existing initiatives in the clinical sector must continue, and further investment must be made by stakeholders to overcome the current limitations in sector growth. Furthermore, global organizations seeking to derive long-term sustainable revenue growth and competitive advantage in the global marketplace from their business units in India must establish an appropriate organizational culture and an effective intra-organizational and industry interface for their operations.

Nanophotonic label-free biosensors for environmental monitoring.

PubMed

Chocarro-Ruiz, Blanca; Fernández-Gavela, Adrián; Herranz, Sonia; Lechuga, Laura M

2017-06-01

The field of environmental monitoring has experienced a substantial progress in the last years but still the on-site control of contaminants is an elusive problem. In addition, the growing number of pollutant sources is accompanied by an increasing need of having efficient early warning systems. Several years ago biosensor devices emerged as promising environmental monitoring tools, but their level of miniaturization and their fully operation outside the laboratory prevented their use on-site. In the last period, nanophotonic biosensors based on evanescent sensing have emerged as an outstanding choice for portable point-of-care diagnosis thanks to their capability, among others, of miniaturization, multiplexing, label-free detection and integration in lab-on-chip platforms. This review covers the most relevant nanophotonic biosensors which have been proposed (including interferometric waveguides, grating-couplers, microcavity resonators, photonic crystals and localized surface plasmon resonance sensors) and their recent application for environmental surveillance. Copyright © 2017 Elsevier Ltd. All rights reserved.

Chemical studies of H chondrites. I - Mobile trace elements and gas retention ages

NASA Technical Reports Server (NTRS)

Lingner, David W.; Huston, Ted J.; Hutson, Melinda; Lipschutz, Michael E.

1987-01-01

Trends for 16 trace elements (Ag, As, Au, Bi, Cd, Co, Cs, Ga, In, K, Rb, Sb, Se, Te, Tl, and Zn), chosen to span a broad geochemical and thermal response range, in 44 H4-6 chondrites, differ widely from those in L4-6 chondrites. In particular, H chondrites classified as heavily shocked petrologically do not necessarily exhibit Ar-40 loss and vice versa. The clear-cut causal relationship between siderophile and mobile element loss with increasing late shock seen in L chondrites is not generally evident in the H group. H chondrite parent material experienced an early high temperature genetic episode that mobilized a substantial proportion of these trace elements so that later thermal episodes resulted in more subtle, collateral fractionations. Mildly shocked L chondrites escaped this early high temperature event, indicating that the two most numerous meteorite groups differ fundamentally in genetic history.

Status and ecological effects of the world's largest carnivores.

PubMed

Ripple, William J; Estes, James A; Beschta, Robert L; Wilmers, Christopher C; Ritchie, Euan G; Hebblewhite, Mark; Berger, Joel; Elmhagen, Bodil; Letnic, Mike; Nelson, Michael P; Schmitz, Oswald J; Smith, Douglas W; Wallach, Arian D; Wirsing, Aaron J

2014-01-10

Large carnivores face serious threats and are experiencing massive declines in their populations and geographic ranges around the world. We highlight how these threats have affected the conservation status and ecological functioning of the 31 largest mammalian carnivores on Earth. Consistent with theory, empirical studies increasingly show that large carnivores have substantial effects on the structure and function of diverse ecosystems. Significant cascading trophic interactions, mediated by their prey or sympatric mesopredators, arise when some of these carnivores are extirpated from or repatriated to ecosystems. Unexpected effects of trophic cascades on various taxa and processes include changes to bird, mammal, invertebrate, and herpetofauna abundance or richness; subsidies to scavengers; altered disease dynamics; carbon sequestration; modified stream morphology; and crop damage. Promoting tolerance and coexistence with large carnivores is a crucial societal challenge that will ultimately determine the fate of Earth's largest carnivores and all that depends upon them, including humans.

Efficiency and productivity assessment of public hospitals in Greece during the crisis period 2009-2012.

PubMed

Xenos, P; Yfantopoulos, J; Nektarios, M; Polyzos, N; Tinios, P; Constantopoulos, A

2017-01-01

This study is an initial effort to examine the dynamics of efficiency and productivity in Greek public hospitals during the first phase of the crisis 2009-2012. Data were collected by the Ministry of Health after several quality controls ensuring comparability and validity of hospital inputs and outputs. Productivity is estimated using the Malmquist Indicator, decomposing the estimated values into efficiency and technological change. Hospital efficiency and productivity growth are calculated by bootstrapping the non-parametric Malmquist analysis. The advantage of this method is the estimation efficiency and productivity through the corresponding confidence intervals. Additionally, a Random-effects Tobit model is explored to investigate the impact of contextual factors on the magnitude of efficiency. Findings reveal substantial variations in hospital productivity over the period from 2009 to 2012. The economic crisis of 2009 had a negative impact in productivity. The average Malmquist Productivity Indicator (MPI) score is 0.72 with unity signifying stable production. Approximately 91% of the hospitals score lower than unity. Substantial increase is observed between 2010 and 2011, as indicated by the average MPI score which fluctuates to 1.52. Moreover, technology change scored more than unity in more than 75% of hospitals. The last period (2011-2012) has shown stabilization in the expansionary process of productivity. The main factors contributing to overall productivity gains are increases in occupancy rates, type and size of the hospital. This paper attempts to offer insights in efficiency and productivity growth for public hospitals in Greece. The results suggest that the average hospital experienced substantial productivity growth between 2009 and 2012 as indicated by variations in MPI. Almost all of the productivity increase was due to technology change which could be explained by the concurrent managerial and financing healthcare reforms. Hospitals operating under decreasing returns to scale could achieve higher efficiency rates by reducing their capacity. However, certain social objectives should also be considered. Emphasis perhaps should be placed in utilizing and advancing managerial and organizational reforms, so that the benefits of technological improvements will have a continuing positive impact in the future.

Short Term Fluctuations in Income and Their Relationship to the Characteristics of the Low Income Population: New Data from the SIPP. Project Report 3751-02.

ERIC Educational Resources Information Center

Ruggles, Patricia

This paper compares the characteristics of those experiencing short spells of low income with those having longer spells. Data from the 1984 panel of the Survey of Income and Program Participation (SIPP) was examined. It was found that short spells--less than six months--are quite common, and make up a substantial proportion of all poverty spells.…

Status of oak seedlings and saplings in the northern United States: implications for sustainability of oak forests

Treesearch

Chris W. Woodall; Randall S. Morin; Jim R. Steinman; Charles H. Perry

2008-01-01

Oak species are a substantial component of forest ecosystems in a 24-state region spanning the northern U.S. During recent decades, it has been documented that the health of oak forests has been experiencing large-scale decline. To further evaluate the sustainability of oak forests in nearly half the states of the U.S., the current status of oak seedlings and saplings...

Perceived Age Discrimination Across Age in Europe: From an Ageing Society to a Society for All Ages

PubMed Central

2017-01-01

Ageism is recognized as a significant obstacle to older people’s well-being, but age discrimination against younger people has attracted less attention. We investigate levels of perceived age discrimination across early to late adulthood, using data from the European Social Survey (ESS), collected in 29 countries (N = 56,272). We test for approximate measurement invariance across countries. We use local structural equation modeling as well as moderated nonlinear factor analysis to test for measurement invariance across age as a continuous variable. Using models that account for the moderate degree of noninvariance, we find that younger people report experiencing the highest levels of age discrimination. We also find that national context substantially affects levels of ageism experienced among older respondents. The evidence highlights that more research is needed to address ageism in youth and across the life span, not just old adulthood. It also highlights the need to consider factors that differently contribute to forms of ageism experienced by people at different life stages and ages. PMID:29058935

Exploring the effectiveness of engagement in a broad range of disciplinary practices on learning of Turkish high-school chemistry students

NASA Astrophysics Data System (ADS)

Seda Cetin, Pinar; Eymur, Guluzar; Southerland, Sherry A.; Walker, Joi; Whittington, Kirby

2018-03-01

This study examines the influence of laboratory instruction that engages students in a wide range of the practices of science on Turkish high-school students' chemistry learning. In this mixed methods study, student learning in two different laboratory settings was compared, one that featured an instruction that engaged students in a wide range of disciplinary practices (through Argument-driven Inquiry - ADI) and similar laboratories in which a more traditional Structured Inquiry (SI) approach was employed. The data sources included a Chemistry Concept test, an Argumentative Writing Assessment, and Semi-structured interviews. After seven weeks of chemistry instruction, students experiencing ADI instruction scored higher on the Chemistry Concept test and the Argumentative Writing Assessment than students experiencing SI instruction. Furthermore, girls who experienced ADI instruction scored higher on the assessments than their majority peers in the same class. The results suggest that Turkish students can substantially improve their chemistry proficiency if they have an opportunity to engage in instruction featuring a broad array of the practices of science.

Psychotropic and Opioid Medication Use in Older Patients With Breast Cancer Across the Care Trajectory: A Population-Based Cohort Study.

PubMed

Syrowatka, Ania; Chang, Sue-Ling; Tamblyn, Robyn; Mayo, Nancy E; Meguerditchian, Ari N

2016-11-01

Older patients with breast cancer represent a vulnerable population at higher risk of experiencing distress and pain, as well as medication-related adverse events from pharmacological treatment of these symptoms. The purpose of this study is to estimate the prevalence of psychotropic (anxiolytic, antidepressant, and antipsychotic) and opioid medication use by older women diagnosed with breast cancer. This population-based cohort study followed 19,353 women older than 65 years diagnosed with incident, nonmetastatic breast cancer in Quebec, Canada. Data were obtained from provincial, universal health and drug insurance plans covering all medical and pharmaceutical care. Descriptive statistics were calculated for demographic information, breast cancer characteristics, and treatments. Psychotropic and opioid medication use was assessed across the care trajectory: precancer baseline, active care, and first-year survivorship. There was a marked increase in the prevalence of medication use from precancer baseline to active care, followed by a decrease into first-year survivorship. Anxiolytics were used most often across the care trajectory (36.3%, 50.6%, and 44.4% at baseline, active care, and survivorship, respectively). In contrast, antipsychotic and opioid medications were sought primarily during active care (4.5- and 7-fold increases from baseline, respectively), with opioid use during active care increasing dramatically over the study period (9.0% to 40.9% from 1998 to 2010). Unlike other drugs, antidepressant use peaked in active care but persisted into survivorship (14.7%, 22.4%, and 22.3% at baseline, active care, and survivorship, respectively). A substantial proportion of older patients with breast cancer use psychotropic and opioid medications. The different patterns of medication use represent distress and pain experienced by patients across the care trajectory. Given that medication use in this vulnerable population is associated with an increased risk of adverse events, a multidimensional approach integrating psychological interventions in cancer care may better address psychosocial needs of older patients with breast cancer. Copyright © 2016 by the National Comprehensive Cancer Network.

Two-level noncontiguous versus three-level anterior cervical discectomy and fusion: a biomechanical comparison.

PubMed

Finn, Michael A; Samuelson, Mical M; Bishop, Frank; Bachus, Kent N; Brodke, Darrel S

2011-03-15

Biomechanical study. To determine biomechanical forces exerted on intermediate and adjacent segments after two- or three-level fusion for treatment of noncontiguous levels. Increased motion adjacent to fused spinal segments is postulated to be a driving force in adjacent segment degeneration. Occasionally, a patient requires treatment of noncontiguous levels on either side of a normal level. The biomechanical forces exerted on the intermediate and adjacent levels are unknown. Seven intact human cadaveric cervical spines (C3-T1) were mounted in a custom seven-axis spine simulator equipped with a follower load apparatus and OptoTRAK three-dimensional tracking system. Each intact specimen underwent five cycles each of flexion/extension, lateral bending, and axial rotation under a ± 1.5 Nm moment and a 100-Nm axial follower load. Applied torque and motion data in each axis of motion and level were recorded. Testing was repeated under the same parameters after C4-C5 and C6-C7 diskectomies were performed and fused with rigid cervical plates and interbody spacers and again after a three-level fusion from C4 to C7. Range of motion was modestly increased (35%) in the intermediate and adjacent levels in the skip fusion construct. A significant or nearly significant difference was reached in seven of nine moments. With the three-level fusion construct, motion at the infra- and supra-adjacent levels was significantly or nearly significantly increased in all applied moments over the intact and the two-level noncontiguous construct. The magnitude of this change was substantial (72%). Infra- and supra-adjacent levels experienced a marked increase in strain in all moments with a three-level fusion, whereas the intermediate, supra-, and infra-adjacent segments of a two-level fusion experienced modest strain moments relative to intact. It would be appropriate to consider noncontiguous fusions instead of a three-level fusion when confronted with nonadjacent disease.

Estimation of mussel population response to hydrologic alteration in a southeastern U.S. stream

USGS Publications Warehouse

Peterson, J.T.; Wisniewski, J.M.; Shea, C.P.; Rhett, Jackson C.

2011-01-01

The southeastern United States has experienced severe, recurrent drought, rapid human population growth, and increasing agricultural irrigation during recent decades, resulting in greater demand for the water resources. During the same time period, freshwater mussels (Unioniformes) in the region have experienced substantial population declines. Consequently, there is growing interest in determining how mussel population declines are related to activities associated with water resource development. Determining the causes of mussel population declines requires, in part, an understanding of the factors influencing mussel population dynamics. We developed Pradel reverse-time, tag-recapture models to estimate survival, recruitment, and population growth rates for three federally endangered mussel species in the Apalachicola- Chattahoochee-Flint River Basin, Georgia. The models were parameterized using mussel tag-recapture data collected over five consecutive years from Sawhatchee Creek, located in southwestern Georgia. Model estimates indicated that mussel survival was strongly and negatively related to high flows during the summer, whereas recruitment was strongly and positively related to flows during the spring and summer. Using these models, we simulated mussel population dynamics under historic (1940-1969) and current (1980-2008) flow regimes and under increasing levels of water use to evaluate the relative effectiveness of alternative minimum flow regulations. The simulations indicated that the probability of simulated mussel population extinction was at least 8 times greater under current hydrologic regimes. In addition, simulations of mussel extinction under varying levels of water use indicated that the relative risk of extinction increased with increased water use across a range of minimum flow regulations. The simulation results also indicated that our estimates of the effects of water use on mussel extinction were influenced by the assumptions about the dynamics of the system, highlighting the need for further study of mussel population dynamics. ?? 2011 Springer Science+Business Media, LLC (outside the USA).

Unpacking the public stigma of problem gambling: The process of stigma creation and predictors of social distancing.

PubMed

Hing, Nerilee; Russell, Alex M T; Gainsbury, Sally M

2016-09-01

Background and aims Public stigma diminishes the health of stigmatized populations, so it is critical to understand how and why stigma occurs to inform stigma reduction measures. This study aimed to examine stigmatizing attitudes held toward people experiencing problem gambling, to examine whether specific elements co-occur to create this public stigma, and to model explanatory variables of this public stigma. Methods An online panel of adults from Victoria, Australia (N = 2,000) was surveyed. Measures were based on a vignette for problem gambling and included demographics, gambling behavior, perceived dimensions of problem gambling, stereotyping, social distancing, emotional reactions, and perceived devaluation and discrimination. A hierarchical linear regression was conducted. Results People with gambling problems attracted substantial negative stereotypes, social distancing, emotional reactions, and status loss/discrimination. These elements were associated with desired social distance, as was perceived that problem gambling is caused by bad character, and is perilous, non-recoverable, and disruptive. Level of contact with problem gambling, gambling involvement, and some demographic variables was significantly associated with social distance, but they explained little additional variance. Discussion and conclusions This study contributes to the understanding of how and why people experiencing gambling problems are stigmatized. Results suggest the need to increase public contact with such people, avoid perpetuation of stereotypes in media and public health communications, and reduce devaluing and discriminating attitudes and behaviors.

Unpacking the public stigma of problem gambling: The process of stigma creation and predictors of social distancing

PubMed Central

Hing, Nerilee; Russell, Alex M. T.; Gainsbury, Sally M.

2016-01-01

Background and aims Public stigma diminishes the health of stigmatized populations, so it is critical to understand how and why stigma occurs to inform stigma reduction measures. This study aimed to examine stigmatizing attitudes held toward people experiencing problem gambling, to examine whether specific elements co-occur to create this public stigma, and to model explanatory variables of this public stigma. Methods An online panel of adults from Victoria, Australia (N = 2,000) was surveyed. Measures were based on a vignette for problem gambling and included demographics, gambling behavior, perceived dimensions of problem gambling, stereotyping, social distancing, emotional reactions, and perceived devaluation and discrimination. A hierarchical linear regression was conducted. Results People with gambling problems attracted substantial negative stereotypes, social distancing, emotional reactions, and status loss/discrimination. These elements were associated with desired social distance, as was perceived that problem gambling is caused by bad character, and is perilous, non-recoverable, and disruptive. Level of contact with problem gambling, gambling involvement, and some demographic variables was significantly associated with social distance, but they explained little additional variance. Discussion and conclusions This study contributes to the understanding of how and why people experiencing gambling problems are stigmatized. Results suggest the need to increase public contact with such people, avoid perpetuation of stereotypes in media and public health communications, and reduce devaluing and discriminating attitudes and behaviors. PMID:27513611

Reflecting on the Germanwings Disaster: A Systematic Review of Depression and Suicide in Commercial Airline Pilots.

PubMed

Pasha, Terouz; Stokes, Paul R A

2018-01-01

The 2015 Germanwings Flight 9525 disaster, in which 150 people were killed after the co-pilot may have intentionally crashed the plane in a suicide attempt, highlights the importance of better understanding the mental health of commercial airline pilots. However, there have been few systematic reviews investigating the topic of mental health in commercial aviation. This systematic review aims to identify the types and prevalence of mental health disorders that commercial airline pilots experience with a focus on mood disorders and suicide risk. A systematic literature search was performed using PubMed, EMBASE, and PsycINFO databases. Eligible studies were assessed and data was extracted and analyzed. 20 studies were identified. The prevalence of depression experienced by commercial airline pilots in this review ranged from 1.9% to 12.6%. Factors that negatively impacted the mental health of pilots included substance abuse, experiencing verbal or sexual abuse, disruption in sleep circadian rhythms and fatigue. This systematic review identifies that commercial airline pilots may experience depression at least as frequently as the general population. Commercial airline pilots experience occupational stressors, such as disrupted circadian rhythms and fatigue which may increase risks of developing mood disorders. Most studies identified in this review were cross-sectional in nature with substantial limitations. There is a clear need for further higher quality longitudinal studies to better understand the mental health of commercial airline pilots.

Global climate change and the mitigation challenge.

PubMed

Princiotta, Frank

2009-10-01

Anthropogenic emissions of greenhouse gases, especially carbon dioxide (CO2), have led to increasing atmospheric concentrations, very likely the primary cause of the 0.8 degrees C warming the Earth has experienced since the Industrial Revolution. With industrial activity and population expected to increase for the rest of the century, large increases in greenhouse gas emissions are projected, with substantial global additional warming predicted. This paper examines forces driving CO2 emissions, a concise sector-by-sector summary of mitigation options, and research and development (R&D) priorities. To constrain warming to below approximately 2.5 degrees C in 2100, the recent annual 3% CO2 emission growth rate needs to transform rapidly to an annual decrease rate of from 1 to 3% for decades. Furthermore, the current generation of energy generation and end-use technologies are capable of achieving less than half of the emission reduction needed for such a major mitigation program. New technologies will have to be developed and deployed at a rapid rate, especially for the key power generation and transportation sectors. Current energy technology research, development, demonstration, and deployment (RDD&D) programs fall far short of what is required.

Topographic changes and their driving factors after 2008 Wenchuan earthquake

NASA Astrophysics Data System (ADS)

Li, Congrong; Wang, Ming; Liu, Kai; Xie, Jun

2018-06-01

The 2008 Wenchuan Earthquake caused topographic change in the stricken areas because of the occurrence of numerous coseismic landslides. The emergence of new landslides and debris flows and movement of loose materials under the driving force of high rainfall could further shape the local topography. Currently, little attention has been paid to continuously monitoring and assessing topographic changes after the major earthquake. In this research, we obtained an elevation dataset (2002, 2010, 2013 and 2015) based on digital elevation model (DEM) data and a DEM extracted from ZY-3 stereo paired images with validation by field measurement. We quantitatively assessed elevation changes in different years and qualitatively analyzed spatiotemporal variation of the terrain and mass movement across the study area. The results show that the earthquake affected area experienced substantial elevation changes caused by seismic forces and subsequent rainfalls. High rainfall after the earthquake have become the biggest driver of elevation reduction, which overwhelmed elevation increase caused by the major earthquake. Increased post-earthquake erosion intensity has caused large amounts of loose materials to accumulate in river channels, and gullies and on upper-middle mountain slopes, which increases the risk of flooding and geo-hazards in the area.

Improving patient access to an interventional US clinic.

PubMed

Steele, Joseph R; Clarke, Ryan K; Terrell, John A; Brightmon, Tonya R

2014-01-01

A continuous quality improvement project was conducted to increase patient access to a neurointerventional ultrasonography (US) clinic. The clinic was experiencing major scheduling delays because of an increasing patient volume. A multidisciplinary team was formed that included schedulers, medical assistants, nurses, technologists, and physicians. The team created an Ishikawa diagram of the possible causes of the long wait time to the next available appointment and developed a flowchart of the steps involved in scheduling and completing a diagnostic US examination and biopsy. The team then implemented a staged intervention that included adjustments to staffing and room use (stage 1); new procedures for scheduling same-day add-on appointments (stage 2); and a lead technician rotation to optimize patient flow, staffing, and workflow (stage 3). Six months after initiation of the intervention, the mean time to the next available appointment had decreased from 25 days at baseline to 1 day, and the number of available daily appointments had increased from 38 to 55. These improvements resulted from a coordinated provider effort and had a net present value of more than $275,000. This project demonstrates that structural changes in staffing, workflow, and room use can substantially reduce scheduling delays for critical imaging procedures. © RSNA, 2014.

Workload and awkward posture problems among small-scale strawberry farmers in Japan.

PubMed

Kumudini, Ganga; Hasegawa, Tetsuya

2009-12-01

Farmers handle heavy workloads, often in awkward postures and experiencing some work related problems. Farmers perceive them as no more than inevitable consequences of farming activities. Although many problems can be prevented or reduced by simple and inexpensive modifications to work, these problems are increasing among farmers. The main focus of the paper was to investigate workload and awkward postures among strawberry farmers and suggest possible solutions to overcome the identified problems. Questionnaires, direct observations and intertwining methods were used to collect the data. Low-level strawberry beds and long working hours were recognized as critical factors that led to farmers' health problems including suffering from low back pain, heavy fatigue, unsteady feeling after work, etc. There was a substantial increase in fatigue in busy seasons compared with slack seasons. When compared with the other workers such as office, technical, sales and blue-collar workers, female farmers' general fatigue level was considerably high. Findings indicated that strawberry farming was a stressful occupation and farmers were strained under heavy workload, monotonous and repetitive work and poor working conditions with frequent fatigue symptoms and severe influence on health.

Who gets custody now? Dramatic changes in children's living arrangements after divorce.

PubMed

Cancian, Maria; Meyer, Daniel R; Brown, Patricia R; Cook, Steven T

2014-08-01

This article reexamines the living arrangements of children following their parents' divorce, using Wisconsin Court Records, updating an analysis that showed relatively small but significant increases in shared custody in the late 1980s and early 1990s. These changes have accelerated markedly in the intervening years: between 1988 and 2008, the proportion of mothers granted sole physical custody fell substantially, the proportion of parents sharing custody increased dramatically, and father-sole custody remained relatively stable. We explore changes in the correlates of alternative custody outcomes, showing that some results from the earlier analysis still hold (for example, cases with higher total family income are more likely to have shared custody), but other differences have lessened (shared-custody cases have become less distinctive as they have become more common). Despite the considerable changes in marriage and divorce patterns over this period, we do not find strong evidence that the changes in custody are related to changes in the characteristics of families experiencing a divorce; rather, changes in custody may be the result of changes in social norms and the process by which custody is determined.

Weight loss surgery improves quality of life in pediatric patients with osteogenesis imperfecta

PubMed Central

Zani, Augusto; Ford-Adams, Martha; Ratcliff, Megan; Bevan, Denise; Inge, Thomas H.; Desai, Ashish

2018-01-01

Background Osteogenesis imperfecta (OI) is an inherited disorder, which causes brittle bones resulting in recurrent fractures. The associated poor mobility of children with OI increases susceptibility to obesity, and obesity further dramatically limits mobility and increases fracture risk. Objectives The aim of this report was to describe outcomes of weight loss surgery (WLS) in two adolescents with severe obesity and OI. Setting Two University Hospitals (in the United Kingdom and in the United States). Methods Two cases of OI treated with WLS were identified. Pre- and post-operative anthropometric and biochemical data and clinical course were reviewed. Results In these 2 cases, preoperative Body Mass Index (BMI) values were 38 and 46 kg/m2. Following laparoscopic sleeve gastrectomy (LSG), BMI decreased by 55% and 60% by 26 and 24 months, respectively. There were no surgical complications and both patients experienced improvement in their mobility and ability to perform activities of daily living. Conclusions WLS effectively treated severe obesity in two OI patients and substantially improved mobility and quality of life, theoretically reducing fracture risk. PMID:26948942

Supply and demand drive a critical transition to dysfunctional fisheries.

PubMed

Fryxell, John M; Hilborn, Ray; Bieg, Carling; Turgeon, Katrine; Caskenette, Amanda; McCann, Kevin S

2017-11-14

There is growing awareness of the need for fishery management policies that are robust to changing environmental, social, and economic pressures. Here we use conventional bioeconomic theory to demonstrate that inherent biological constraints combined with nonlinear supply-demand relationships can generate threshold effects due to harvesting. As a result, increases in overall demand due to human population growth or improvement in real income would be expected to induce critical transitions from high-yield/low-price fisheries to low-yield/high-price fisheries, generating severe strains on social and economic systems as well as compromising resource conservation goals. As a proof of concept, we show that key predictions of the critical transition hypothesis are borne out in oceanic fisheries (cod and pollock) that have experienced substantial increase in fishing pressure over the past 60 y. A hump-shaped relationship between price and historical harvest returns, well demonstrated in these empirical examples, is particularly diagnostic of fishery degradation. Fortunately, the same heuristic can also be used to identify reliable targets for fishery restoration yielding optimal bioeconomic returns while safely conserving resource abundance. Copyright © 2017 the Author(s). Published by PNAS.

Advanced Glycation End Products: Link between Diet and Ovulatory Dysfunction in PCOS?

PubMed Central

Garg, Deepika; Merhi, Zaher

2015-01-01

PCOS is the most common cause of anovulation in reproductive-aged women with 70% experiencing ovulatory problems. Advanced glycation end products are highly reactive molecules that are formed by non-enzymatic reactions of sugars with proteins, nucleic acids and lipids. AGEs are also present in a variety of diet where substantial increase in AGEs can result due to thermal processing and modifications of food. Elevation in bodily AGEs, produced endogenously or absorbed exogenously from high-AGE diets, is further exaggerated in women with PCOS and is associated with ovulatory dysfunction. Additionally, increased expression of AGEs as pro-inflammatory receptors in the ovarian tissue has been observed in women with PCOS. In this review, we summarize the role of dietary AGEs as mediators of metabolic and reproductive alterations in PCOS. Once a mechanistic understanding of the relationship between AGEs and anovulation is established, there is a promise that such knowledge will contribute to the subsequent development of targeted pharmacological therapies that will treat anovulation and improve ovarian health in women with PCOS. PMID:26690206

Nonlinear Meridional Moisture Advection and the ENSO-Southern China Rainfall Teleconnection

NASA Astrophysics Data System (ADS)

Wang, Qiang; Cai, Wenju; Zeng, Lili; Wang, Dongxiao

2018-05-01

In the boreal cooler months of 2015, southern China (SC) experienced the largest rainfall since 1950, exceeding 4 times the standard deviation of SC rainfall. Although an El Niño typically induces a positive SC rainfall anomaly during these months, the unprecedented rainfall increase cannot be explained by the strong El Niño of 2015/2016, and the dynamics is unclear. Here we show that a nonlinear meridional moisture advection contributes substantially to the unprecedented rainfall increase. During cooler months of 2015, the meridional flow anomaly over the South China Sea region, which acts on an El Niño-induced anomalous meridional moisture gradient, is particularly large and is supported by an anomalous zonal sea surface temperature gradient over the northwestern Pacific, which recorded its largest value in 2015 since 1950. Our study highlights, for the first time, the importance of the nonlinear process associated with the combined impact of a regional sea surface temperature gradient and large-scale El Niño anomalies in forcing El Niño rainfall teleconnection.

Carbon nanotube-based sensor and method for detection of crack growth in a structure

NASA Technical Reports Server (NTRS)

Smits, Jan M. (Inventor); Moore, Thomas C. (Inventor); Kite, Marlen T. (Inventor); Wincheski, Russell A. (Inventor); Ingram, JoAnne L. (Inventor); Watkins, Anthony N. (Inventor); Williams, Phillip A. (Inventor)

2007-01-01

A sensor has a plurality of carbon nanotube (CNT)-based conductors operatively positioned on a substrate. The conductors are arranged side-by-side, such as in a substantially parallel relationship to one another. At least one pair of spaced-apart electrodes is coupled to opposing ends of the conductors. A portion of each of the conductors spanning between each pair of electrodes comprises a plurality of carbon nanotubes arranged end-to-end and substantially aligned along an axis. Because a direct correlation exists between the resistance of a carbon nanotube and its strain, changes experienced by the portion of the structure to which the sensor is coupled induce a corresponding change in the electrical properties of the conductors, thereby enabling detection of crack growth in the structure.

A dynamical context for the origin of Phobos and Deimos

NASA Astrophysics Data System (ADS)

Hansen, Bradley M. S.

2018-04-01

We show that a model in which Mars grows near Earth and Venus but is then scattered out of the terrestrial region yields a natural pathway to explain the low masses of the Martian moons Phobos and Deimos. In this scenario, the last giant impact experienced by Mars is followed by an extended period (tens to hundreds of Myr) of close passages by other planetary embryos. These close passages perturb and dynamically heat any system of forming satellites left over by the giant impact and can substantially reduce the mass in the satellite system (sometimes to zero). The close passage of massive perturbing bodies also offers the opportunity to capture small objects by three-body scattering. Both mechanisms lead to low-mass moon systems with a substantially collisional history.

A Computer-Aided Diagnosis System Using Artificial Intelligence for the Diagnosis and Characterization of Thyroid Nodules on Ultrasound: Initial Clinical Assessment.

PubMed

Choi, Young Jun; Baek, Jung Hwan; Park, Hye Sun; Shim, Woo Hyun; Kim, Tae Yong; Shong, Young Kee; Lee, Jeong Hyun

2017-04-01

An initial clinical assessment is described of a new, commercially available, computer-aided diagnosis (CAD) system using artificial intelligence (AI) for thyroid ultrasound, and its performance is evaluated in the diagnosis of malignant thyroid nodules and categorization of nodule characteristics. Patients with thyroid nodules with decisive diagnosis, whether benign or malignant, were consecutively enrolled from November 2015 to February 2016. An experienced radiologist reviewed the ultrasound image characteristics of the thyroid nodules, while another radiologist assessed the same thyroid nodules using the CAD system, providing ultrasound characteristics and a diagnosis of whether nodules were benign or malignant. The diagnostic performance and agreement of US characteristics between the experienced radiologist and the CAD system were compared. In total, 102 thyroid nodules from 89 patients were included; 59 (57.8%) were benign and 43 (42.2%) were malignant. The CAD system showed a similar sensitivity as the experienced radiologist (90.7% vs. 88.4%, p > 0.99), but a lower specificity and a lower area under the receiver operating characteristic (AUROC) curve (specificity: 74.6% vs. 94.9%, p = 0.002; AUROC: 0.83 vs. 0.92, p = 0.021). Classifications of the ultrasound characteristics (composition, orientation, echogenicity, and spongiform) between radiologist and CAD system were in substantial agreement (κ = 0.659, 0.740, 0.733, and 0.658, respectively), while the margin showed a fair agreement (κ = 0.239). The sensitivity of the CAD system using AI for malignant thyroid nodules was as good as that of the experienced radiologist, while specificity and accuracy were lower than those of the experienced radiologist. The CAD system showed an acceptable agreement with the experienced radiologist for characterization of thyroid nodules.

Evaluation of Bikers Against Child Abuse (BACA) program: A community intervention for child abuse victims.

PubMed

Ray, Dee C; Lilly, J P; Gallina, Nancy; MacIan, Paula; Wilson, Brittany

2017-12-01

Children who have experienced physical abuse benefit from a multitude of community interventions including support programs to address emotional and behavioral stability. This pilot study evaluated the services of Bikers Against Child Abuse (BACA), a community of bikers lending intervention to abused children, using a pre/post exploratory design. Participants (N=154) were children who had been referred by parents/guardians for current or past physical and/or sexual abuse. Parents/guardians of children were interviewed four times over a course of one year. Results indicated children demonstrated substantial improvements in their overall levels of emotional distress, conduct concerns, hyperactivity, and behavioral and emotional functioning. Overall, results support the premise that services provided by BACA may serve as a unique intervention for children who have experienced abuse. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Presence of New Psychoactive Substances in a Tor Network Marketplace Environment.

PubMed

Dolliver, Diana S; Kuhns, Joseph B

2016-01-01

Prior research has documented the availability of drugs on many Tor Network websites, with the Internet playing a particularly vital role in the global new psychoactive substances (NPS) market. The primary objective of this research was to document types of NPS for sale on the largest operating Tor site (Agora) over a period of four months. Secondary objectives were to analyze countries and vendors sourcing NPS on Agora. Data from Agora were collected in February and June 2015. The number of total advertisements on Agora increased from 20,742 to 27,431 over the four months, while the number of NPS advertisements increased from 2,205 to 2,271 and the number of vendors increased from 157 to 288. The composition of NPS listings and source countries for NPS advertised on Agora diversified over time. Advertisements for ketamine and unclassified NPS experienced substantial growth, while the availability of phenethylamines decreased. However, phenethylamines remained the most frequently advertised NPS type. China and the U.S. were found to be the top two countries by volume selling NPS on Agora over the fpir months, but the number of countries identified as advertising NPS increased by nearly 43%. The United States housed the most NPS vendors.

The neural effects of positively and negatively re-experiencing mental fatigue sensation: a magnetoencephalography study.

PubMed

Ishii, Akira; Ishizuka, Takuya; Muta, Yuki; Tanaka, Masaaki; Yamano, Emi; Watanabe, Yasuyoshi

2018-06-01

Fatigue sensation is an essential biological alarm that urges us to take rest to avoid disrupting homeostasis and thus plays an important role in maintaining well-being. However, there are situations in which the anticipation of unpleasant fatigue sensation undesirably reduces motivation for activity. The aim of this study was to examine whether thinking positively about the fatigue sensation would increase motivation to accomplish the workload. Fourteen healthy male volunteers participated in this study and performed a two-back test for 30 min to induce mental fatigue sensation. After their subjective level of fatigue had recovered to the baseline level, they re-experienced the fatigue sensation experienced in the two-back test positively, negatively, and without any modification (i.e., re-experienced the fatigue sensation as it was). The level of motivation to perform another two-back test they felt during the re-experiencing was assessed. The neural activity related to the re-experiencing was recorded using magnetoencephalography. The level of the motivation to perform another two-back test was increased by positively re-experiencing the fatigue sensation. The increase in delta band power in Brodmann area 7 was positively associated with the increase in motivation. These results show that positive thinking about fatigue sensation can enhance motivation and suggest that this enhanced motivation may have some effects on visual attention system.

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacAllister, D.J.; Day, R.; McCormack, M.D.

This paper gives an overview of a major integrated oil company`s experience with artificial intelligence (AI) over the last 5 years, with an emphasis on expert systems. The authors chronicle the development of an AI group, including details on development tool selection, project selection strategies, potential pitfalls, and descriptions of several completed expert systems. Small expert systems produced by teams of petroleum technology experts and experienced expert system developers that are focused in well-defined technical areas have produced substantial benefits and accelerated petroleum technology transfer.

Predicting changes in hydrologic retention in an evolving semi-arid alluvial stream

USGS Publications Warehouse

Harvey, J.W.; Conklin, M.H.; Koelsch, R.S.

2003-01-01

Hydrologic retention of solutes in hyporheic zones or other slowly moving waters of natural channels is thought to be a significant control on biogeochemical cycling and ecology of streams. To learn more about factors affecting hydrologic retention, we repeated stream-tracer injections for 5 years in a semi-arid alluvial stream (Pinal Creek, Ariz.) during a period when streamflow was decreasing, channel width increasing, and coverage of aquatic macrophytes expanding. Average stream velocity at Pinal Creek decreased from 0.8 to 0.2 m/s, average stream depth decreased from 0.09 to 0.04 m, and average channel width expanded from 3 to 13 m. Modeling of tracer experiments indicated that the hydrologic retention factor (Rh), a measure of the average time that solute spends in storage per unit length of downstream transport, increased from 0.02 to 8 s/m. At the same time the ratio of cross-sectional area of storage zones to main channel cross-sectional area (As/A) increased from 0.2 to 0.8 m2/m2, and average water residence time in storage zones (ts) increased from 5 to 24 min. Compared with published data from four other streams in the US, Pinal Creek experienced the greatest change in hydrologic retention for a given change in streamflow. The other streams differed from Pinal Creek in that they experienced a change in streamflow between tracer experiments without substantial geomorphic or vegetative adjustments. As a result, a regression of hydrologic retention on streamflow developed for the other streams underpredicted the measured increases in hydrologic retention at Pinal Creek. The increase in hydrologic retention at Pinal Creek was more accurately predicted when measurements of the Darcy-Weisbach friction factor were used (either alone or in addition to streamflow) as a predictor variable. We conclude that relatively simple measurements of channel friction are useful for predicting the response of hydrologic retention in streams to major adjustments in channel morphology as well as changes in streamflow. Published by Elsevier Ltd.

The extreme drought episode of August 2011-May 2012: A scenario for future droughts in Central Europe?

NASA Astrophysics Data System (ADS)

Zahradníček, P.; Trnka, M.; Brázdil, R.; Mozny, M.; Stepanek, P.; Hlavinka, P.; Malý, A.; Dubrovsky, M.

2014-12-01

The weather conditions from August 2011 to May 2012 produced an extreme drought in the eastern Czech Republic (Moravia), whereas the patterns were nearly normal in its western region (Bohemia). The Southern and Central Moravia regions, which represent the most important agricultural areas, were most affected by the drought. The precipitation totals for the studied period were 50% to 70% of the long-term mean, which was calculated for 1961-2000. In autumn 2011, the total precipitation accounted for 10% to 30% of the long-term mean for most of Moravia, increasing to 30% to 50% in spring 2012. Moreover, 7.5% of the Czech Republic experienced a 100-year drought; 20% of the country experienced a 20-year drought. According to the Palmer Drought Severity Index, the 2012 drought was classified as the worst in the past 130 years. The drought patterns were related to the prevailing high-pressure systems over Central Europe and the occurrence of weather types with different precipitation amounts in Bohemia and Moravia. The most substantial drought effects occurred in the agricultural sector. A decrease in cereal yields was observed in the analyzed production areas in Moravia, which was unprecedented in the past 52 years. Moreover, winter crops were affected more than spring crops. An increased risk of fire occurred due to the drought conditions; the largest forest fire in the past 15 years was recorded during this period. Furthermore, signs of hydrological drought were also reported in rivers. The 2011-2012 drought was compared with the significant droughts in 2000, 2003 and 2007. Austria and Slovakia, which neighbor the Czech Republic, experienced a similar drought. This drought analysis can be used as a scenario for future droughts and their impacts in Central Europe due to the global warming projected by GCMs.Acknowledgements:This study was made possible by the generous support of the "Establishment of International Scientific Team Focused on Drought Research" project (no. OP VK CZ.1.07/2.3.00/20.0248).

Long-term and widespread changes in agricultural practices influence ring-necked pheasant abundance in California

USGS Publications Warehouse

Coates, Peter S.; Brussee, Brianne E.; Howe, Kristy B.; Fleskes, Joseph P.; Dwight, Ian; Connelly, Daniel P.; Meshriy, Matt G.; Gardner, Scott C.

2017-01-01

Declines in bird populations in agricultural regions of North America and Europe have been attributed to agricultural industrialization, increases in use of agrochemical application, and increased predation related to habitat modification. Based on count data compiled from Breeding Bird Survey (BBS) from 1974 to 2012, Christmas Bird Count (CBC) collected from 1914 to 2013, and hunter data from Annual Game Take Survey (AGTS) for years 1948–2010, ring-necked pheasants (Phasianus colchicus) in California have experienced substantial declines in agricultural environments. Using a modeling approach that integrates all three forms of survey data into a joint response abundance index, we found pheasant abundance was related to the amount of harvested and unharvested crop land, types of crops produced, amount of total pesticide applied, minimum temperature, precipitation, and numbers of avian competitors and predators. Specifically, major changes in agricultural practices over the last three decades were associated with declines in pheasant numbers and likely reflected widespread loss of habitat. For example, increases in cropland were associated with increased pheasant abundance during early years of study but this effect decreased through time, such that no association in recent years was evidenced. A post hoc analysis revealed that crops beneficial to pheasant abundance (e.g., barley) have declined substantially in recent decades and were replaced by less advantageous crops (e.g., nut trees). An additional analysis using a restricted data set (1990–2013) indicated recent negative impacts on pheasant numbers associated with land use practices were also associated with relatively high levels of pesticide application. Our results may provide valuable information for management policies aimed at reducing widespread declines in pheasant populations in California and may be applicable to other avian species within agricultural settings. Furthermore, this general analytical approach is not limited to pheasants and could be applied to other taxa for which multiple survey data sources exist.

Trends in mortality from 1965 to 2008 across the English north-south divide: comparative observational study.

PubMed

Hacking, John M; Muller, Sara; Buchan, Iain E

2011-02-15

To compare all cause mortality between the north and south of England over four decades. Population wide comparative observational study of mortality. Five northernmost and four southernmost English government office regions. All residents in each year from 1965 to 2008. Death rate ratios of north over south England by age band and sex, and northern excess mortality (percentage of excess deaths in north compared with south, adjusted for age and sex and examined for annual trends, using Poisson regression). During 1965 to 2008 the northern excess mortality remained substantial, at an average of 13.8% (95% confidence interval 13.7% to 13.9%). This geographical inequality was significantly larger for males than for females (14.9%, 14.7% to 15.0% v 12.7%, 12.6% to 12.9%, P<0.001). The inequality decreased significantly but temporarily for both sexes from the early 80s to the late 90s, followed by a steep significant increase from 2000 to 2008. Inequality varied with age, being higher for ages 0-9 years and 40-74 years and lower for ages 10-39 years and over 75 years. Time trends also varied with age. The strongest trend over time by age group was the increase among the 20-34 age group, from no significant northern excess mortality in 1965-95 to 22.2% (18.7% to 26.0%) in 1996-2008. Overall, the north experienced a fifth more premature (<75 years) deaths than the south, which was significant: a pattern that changed only by a slight increase between 1965 and 2008. Inequalities in all cause mortality in the north-south divide were severe and persistent over the four decades from 1965 to 2008. Males were affected more than females, and the variation across age groups was substantial. The increase in this inequality from 2000 to 2008 was notable and occurred despite the public policy emphasis in England over this period on reducing inequalities in health.

Biogeochemical phosphorus mass balance for Lake Baikal, southeastern Siberia, Russia

USGS Publications Warehouse

Callender, E.; Granina, L.

1997-01-01

Extensive data for Lake Baikal have been synthesized into a geochemical mass balance for phosphorus (P). Some of the P budget and internal cycling terms for Baikal have been compared to similar terms for oligotrophic Lake Superior, mesotrophic Lake Michigan and the Baltic Sea, and the Ocean. Lake Baikal has a large external source of fluvial P compared to the Laurentian upper Great Lakes and the Ocean. The major tributary to Lake Baikal has experienced substantial increases in organic P loading during the past 25 years. This, coupled with potential P inputs from possible phosphorite mining, may threaten Baikal's oligotrophic status in the future. Water-column remineralization of particulate organic P is substantially greater in Lake Baikal than in the Laurentian Great Lakes. This is probably due to the great water depths of Lake Baikal. There is a gradient in P burial efficiency, with very high values (80%) for Lake Baikal and Lake Superior, lower values (50%) for Lake Michigan and the Baltic Sea, and a low value (13%) for the Ocean. The accumulation rate of P in Lake Baikal sediments is somewhat greater than that in the Laurentian upper Great Lakes and the Baltic Sea, and much greater than in the Ocean. Benthic regeneration rates are surprisingly similar for large lacustrine and marine environments and supply less than 10% of the P utilized for primary production in these aquatic environments.

Facebook network structure and awareness of preexposure prophylaxis among young men who have sex with men.

PubMed

Khanna, Aditya S; Schumm, Phil; Schneider, John A

2017-03-01

Young Black men who have sex with men (YBMSM) are the only population in the United States who have experienced rising human immunodeficiency virus incidence over the past decade. Consistent pre-exposure prophylaxis (PrEP) use can substantially reduce the risk of human immunodeficiency virus acquisition. What differentiates those who become aware of PrEP, and those who do not, remains largely unknown. The social networks of YBMSM can impact their awareness of PrEP; to examine this impact, we used two waves of Facebook data from "uConnect"-a longitudinal cohort study of YBMSM in Chicago (n = 266). While PrEP awareness increased from 45% at baseline to 75% at follow-up, its use remained low (4% and 6%). There were 88 PrEP-unaware individuals at baseline who became aware (BA) by follow-up, and 56 who remained persistently unaware. While the persistently unawares had a higher median number of total Facebook friends, the BAs had a higher median numbers of friends who participated in uConnect, who were PrEP-aware, and who practiced behaviors previously found to be associated with individual-level awareness of PrEP at baseline. The BAs also had substantially more "influential" friends. These findings demonstrate the potential of social networks in raising PrEP awareness and use among YBMSM. Copyright © 2016 Elsevier Inc. All rights reserved.

A Comparison between Chocolate Milk and a Raw Milk Honey Solution’s Influence on Delayed Onset of Muscle Soreness

PubMed Central

Hatchett, Andrew; Berry, Christopher; Oliva, Claudia; Wiley, Douglas; St. Hilaire, Jacob; LaRochelle, Alex

2016-01-01

This investigation sought to examine the effect that a chocolate milk solution (CMS) and a raw milk solution (RMS) had on lower extremity induced delayed onset of muscle soreness (DOMS). Twenty trained male participants completed a set of questionnaires, prior to completing a lower extremity DOMS protocol, to determine the level of discomfort and functional limitations. Once the DOMS protocol was completed, participants were randomly assigned to either the CM or RM group. Once assigned, participants ingested 240 mL of the respective solution and completed the same set of questionnaires immediately post, 24-, 48- and 72-h post DOMS protocol. Additionally, for 10 days post-ingestion participants were contacted to learn if any negative effects were experienced as a result of ingesting either solution. Both groups reported an increase in lower extremity discomfort at each data collection interval post-DOMS protocol (post, 24-, 48- and 72-h). Participants assigned to the RM group reported high discomfort post and a relative decline in discomfort from immediately post-DOMS protocol to 72-h post. The RMS group reported substantially less discomfort at 72-h when compared to the CMS group. Ingestion of a raw milk solution immediately post strength exercise can substantially reduce the level of self-reported discomfort associated with DOMS. PMID:29910267

MetaboAnalyst 3.0--making metabolomics more meaningful.

PubMed

Xia, Jianguo; Sinelnikov, Igor V; Han, Beomsoo; Wishart, David S

2015-07-01

MetaboAnalyst (www.metaboanalyst.ca) is a web server designed to permit comprehensive metabolomic data analysis, visualization and interpretation. It supports a wide range of complex statistical calculations and high quality graphical rendering functions that require significant computational resources. First introduced in 2009, MetaboAnalyst has experienced more than a 50X growth in user traffic (>50 000 jobs processed each month). In order to keep up with the rapidly increasing computational demands and a growing number of requests to support translational and systems biology applications, we performed a substantial rewrite and major feature upgrade of the server. The result is MetaboAnalyst 3.0. By completely re-implementing the MetaboAnalyst suite using the latest web framework technologies, we have been able substantially improve its performance, capacity and user interactivity. Three new modules have also been added including: (i) a module for biomarker analysis based on the calculation of receiver operating characteristic curves; (ii) a module for sample size estimation and power analysis for improved planning of metabolomics studies and (iii) a module to support integrative pathway analysis for both genes and metabolites. In addition, popular features found in existing modules have been significantly enhanced by upgrading the graphical output, expanding the compound libraries and by adding support for more diverse organisms. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

From F = ma to Flying Squirrels: Curricular Change in an Introductory Physics Course

PubMed Central

O’Shea, Brian; Terry, Laura; Benenson, Walter

2013-01-01

We present outcomes from curricular changes made to an introductory calculus-based physics course whose audience is primarily life sciences majors, the majority of whom plan to pursue postbaccalaureate studies in medical and scientific fields. During the 2011–2012 academic year, we implemented a Physics of the Life Sciences curriculum centered on a draft textbook that takes a novel approach to teaching physics to life sciences majors. In addition, substantial revisions were made to the homework and hands-on components of the course to emphasize the relationship between physics and the life sciences and to help the students learn to apply physical intuition to life sciences–oriented problems. Student learning and attitudinal outcomes were assessed both quantitatively, using standard physics education research instruments, and qualitatively, using student surveys and a series of postsemester interviews. Students experienced high conceptual learning gains, comparable to other active learning–based physics courses. Qualitatively, a substantial fraction of interviewed students reported an increased interest in physics relative to the beginning of the semester. Furthermore, more than half of students self-reported that they could now relate physics topics to their majors and future careers, with interviewed subjects demonstrating a high level of ability to come up with examples of how physics affects living organisms and how it helped them to better understand content presented in courses in their major. PMID:23737630

From F = ma to flying squirrels: curricular change in an introductory physics course.

PubMed

O'Shea, Brian; Terry, Laura; Benenson, Walter

2013-06-01

We present outcomes from curricular changes made to an introductory calculus-based physics course whose audience is primarily life sciences majors, the majority of whom plan to pursue postbaccalaureate studies in medical and scientific fields. During the 2011-2012 academic year, we implemented a Physics of the Life Sciences curriculum centered on a draft textbook that takes a novel approach to teaching physics to life sciences majors. In addition, substantial revisions were made to the homework and hands-on components of the course to emphasize the relationship between physics and the life sciences and to help the students learn to apply physical intuition to life sciences-oriented problems. Student learning and attitudinal outcomes were assessed both quantitatively, using standard physics education research instruments, and qualitatively, using student surveys and a series of postsemester interviews. Students experienced high conceptual learning gains, comparable to other active learning-based physics courses. Qualitatively, a substantial fraction of interviewed students reported an increased interest in physics relative to the beginning of the semester. Furthermore, more than half of students self-reported that they could now relate physics topics to their majors and future careers, with interviewed subjects demonstrating a high level of ability to come up with examples of how physics affects living organisms and how it helped them to better understand content presented in courses in their major.

A comparison of temporal Facebook networks of young men who have sex with men (MSM), differentiated by awareness and use of preexposure prophylaxis (PrEP)

PubMed Central

Khanna, Aditya S.; Schumm, Phil; Schneider, John A.

2016-01-01

Young Black men who have sex with men (YBMSM) are the only population in the U.S. who have experienced rising HIV incidence over the past decade. Consistent preexposure prophylaxis (PrEP) use can substantially reduce the risk of HIV acquisition. What differentiates those who become aware of PrEP, and those who do not, remains largely unknown. The social networks of YBMSM can impact their awareness of PrEP; to examine this impact, we used two waves of Facebook data from the “uConnect” study – a longitudinal cohort study of YBMSM in Chicago (n=266). While PrEP awareness increased from 45% at baseline to 75% at follow-up, its use remained low (4% and 6%). There were 88 PrEP-unaware individuals at baseline who became aware (BA) by follow-up, and 56 who remained persistently unaware (PU). While the PUs had a higher median number of total Facebook friends, the BAs had a higher median numbers of friends who participated in uConnect, who were PrEP-aware, and who practiced behaviors previously found to be associated with individual-level awareness of PrEP at baseline. The BAs also had substantially more “influential” friends. These findings demonstrate the potential of social networks in raising PrEP awareness and use among YBMSM. PMID:28003117

Virtual chromoendoscopy can be a useful software tool in capsule endoscopy.

PubMed

Duque, Gabriela; Almeida, Nuno; Figueiredo, Pedro; Monsanto, Pedro; Lopes, Sandra; Freire, Paulo; Ferreira, Manuela; Carvalho, Rita; Gouveia, Hermano; Sofia, Carlos

2012-05-01

capsule endoscopy (CE) has revolutionized the study of small bowel. One major drawback of this technique is that we cannot interfere with image acquisition process. Therefore, the development of new software tools that could modify the images and increase both detection and diagnosis of small-bowel lesions would be very useful. The Flexible Spectral Imaging Color Enhancement (FICE) that allows for virtual chromoendoscopy is one of these software tools. to evaluate the reproducibility and diagnostic accuracy of the FICE system in CE. this prospective study involved 20 patients. First, four physicians interpreted 150 static FICE images and the overall agreement between them was determined using the Fleiss Kappa Test. Second, two experienced gastroenterologists, blinded to each other results, analyzed the complete 20 video streams. One interpreted conventional capsule videos and the other, the CE-FICE videos at setting 2. All findings were reported, regardless of their clinical value. Non-concordant findings between both interpretations were analyzed by a consensus panel of four gastroenterologists who reached a final result (positive or negative finding). in the first arm of the study the overall concordance between the four gastroenterologists was substantial (0.650). In the second arm, the conventional mode identified 75 findings and the CE-FICE mode 95. The CE-FICE mode did not miss any lesions identified by the conventional mode and allowed the identification of a higher number of angiodysplasias (35 vs 32), and erosions (41 vs. 24). there is reproducibility for the interpretation of CE-FICE images between different observers experienced in conventional CE. The use of virtual chromoendoscopy in CE seems to increase its diagnostic accuracy by highlighting small bowel erosions and angiodysplasias that weren´t identified by the conventional mode.

L2 Teachers' Pedagogic Knowledge Base: A Comparison between Experienced and Less Experienced Practitioners

ERIC Educational Resources Information Center

Akbari, Ramin; Tajik, Leila

2009-01-01

Second language teacher education community has become increasingly interested in the pedagogical knowledge base of teachers as a window into practitioners' mental lives. The present study was conducted to document likely differences between the pedagogic thoughts of experienced and less experienced teachers. Eight teachers participated in the…

An evaluation of the predictive validity and inter-rater reliability of clinical diagnostic criteria for senile dementia of Lewy body type.

PubMed

McKeith, I G; Fairbairn, A F; Bothwell, R A; Moore, P B; Ferrier, I N; Thompson, P; Perry, R H

1994-05-01

Several recent autopsy studies suggest that senile dementia of Lewy body type (SDLT) may be the second most common neuropathologic cause of dementia in the elderly, accounting for 7 to 30% of all cases. Operational criteria for the antemortem clinical diagnosis of SDLT have already been proposed by our group. The performance of these is now examined by randomizing the case notes from a new series of SDLT, Alzheimer, and multi-infarct dementia patients for psychiatric assessment by four raters of varying clinical experience and blind to pathologic diagnosis. Using the SDLT criteria, the two most experienced raters agreed in 94% of cases (kappa = 0.87), with the least experienced rater agreeing in 78% (kappa = 0.50). Diagnostic specificity for SDLT was uniformly high (90.0 to 97.0%), with a mean sensitivity of detection of 74%, and was greater by the experienced (90.0%) than the least experienced (55%) clinician. The antemortem identification of SDLT patients can therefore be achieved with a high degree of diagnostic specificity using such operationalized criteria, although there remains a minority of patients who present with either "typical" Alzheimer-type symptoms or with paranoid or delusional symptoms in the absence of substantial cognitive impairment. Sensitivity to neuroleptics may be a useful diagnostic pointer in these patients.

Social Correlates of the Chronic Stress of Perceived Racism Among Black Women

PubMed Central

Vines, Anissa I.; Baird, Donna D.; McNeilly, Maya; Hertz-Picciotto, Irva; Light, Kathleen C.; Stevens, June

2010-01-01

Objectives This study describes the perceptions of racism, passive and active responses to this psychosocial stressor, and it examines socioeconomic correlates of perceived racism in an economically diverse population of Black women. Methods The Telephone-Administered Perceived Racism Scale was administered to 476 Black women, aged 36 to 53 years, who were randomly selected from a large health plan. Results The percentage of respondents who reported personally experiencing racism in the past five years ranged from 66% to 93%, depending on the specific item asked. When respondents were asked about racism toward Blacks as a group, perceptions of racism were even higher. For example, 68% “agreed” or “strongly agreed” that they had personally experienced being followed or watched while shopping because of their race, and 93% reported that Blacks in general experience this form of discrimination. Strong emotional responses to racism were often reported, and though more respondents (41%) reported experiencing very strong active emotions including anger, a substantial group (16%) reported experiencing very strong passive emotions such as powerlessness. Higher education was associated with higher perceived racism, while growing up in a middle-income or well-off family was associated with lower perceived racism and reduced likelihood of passive responses to racism. Conclusions The high prevalence of perceived racism in this study population warrants further examination of this stressor as a potential determinant of racial health disparities. Higher education and income do not appear to protect women from experiencing racism and feeling hopeless or powerless in response. PMID:16599356

Double trouble: violent and non-violent traumas among women at sexual risk of HIV infection.

PubMed

Brown-Peterside, Pamela; Ren, Leigh; Chiasson, Mary Ann; Koblin, Beryl A

2002-01-01

This study examines the association between trauma and HIV risk behaviors among women at sexual risk for HIV infection. From April to August 1998, high-risk HIV negative women were recruited in the South Bronx into a year-long cohort study. At the 12-month visit, 116 women were interviewed face-to-face about recent and lifetime violent and non-violent traumas. The women reported a substantial prevalence of sexual risk behaviors associated with the acquisition of HIV. At baseline, almost two-thirds (64%) reported unprotected vaginal sex in the previous six months, and in the previous year, 62% had smoked crack, 52% reported sex-for-money-or-drugs exchanges, and 47% had five or more male sex partners. The lifetime prevalence of trauma was high: 81% had experienced one or more violent traumas and 97% had experienced one or more non-violent traumas. Women who had experienced violent trauma--physical assault by a partner (OR = 2.88; 95% CI 1.12; 7.41)--and those who had experienced non-violent trauma--loss of a child to foster care (OR = 3.34; 95% CI 1.04; 10.65)--were more likely to use crack than others. Those who had experienced non-violent trauma, by witnessing a physical assault (OR = 2.31; 95% CI 0.99; 5.40), were also more likely than others to have exchanged sex. Both violent and non-violent traumas appear to play a role in the behaviors that place women at risk of HIV infection, particularly using crack and exchanging sex.

Corrosion testing using isotopes

DOEpatents

Hohorst, Frederick A.

1995-12-05

A method for determining the corrosion behavior of a material with respect to a medium in contact with the material by: implanting a substantially chemically inert gas in a matrix so that corrosion experienced by the material causes the inert gas to enter the medium; placing the medium in contact with the material; and measuring the amount of inert gas which enters the medium. A test sample of a material whose resistance to corrosion by a medium is to be tested, composed of: a body of the material, which body has a surface to be contacted by the medium; and a substantially chemically inert gas implanted into the body to a depth below the surface. A test sample of a material whose resistance to corrosion by a medium is to be tested, composed of: a substrate of material which is easily corroded by the medium, the substrate having a surface; a substantially chemically inert gas implanted into the substrate; and a sheet of the material whose resistance to corrosion is to be tested, the sheet being disposed against the surface of the substrate and having a defined thickness.

He said what? Physiological and cognitive responses to imagining and witnessing outgroup racism.

PubMed

Karmali, Francine; Kawakami, Kerry; Page-Gould, Elizabeth

2017-08-01

Responses to outgroup racism can have serious implications for the perpetuation of bias, yet research examining this process is rare. The present research investigated self-reported, physiological, and cognitive responses among "experiencers" who witnessed and "forecasters" who imagined a racist comment targeting an outgroup member. Although previous research indicates that experiencers self-reported less distress and chose a racist partner more often than forecasters, the present results explored the possibility that experiencers may actually be distressed in such situation but regulate their initial affective reactions. The results from Experiment 1 demonstrated that participants in both roles showed (a) no activation of the hypothalamic pituitary adrenal stress axis (decreased cortisol) and (b) activation of the sympathetic autonomic nervous system (increased skin conductance). However, experiencers but not forecasters displayed a physiological profile indicative of an orienting response (decreased heart rate and increased skin conductance) rather than a defensive response (increased heart rate and increased skin conductance). Furthermore, the results from Experiment 2 provided additional evidence that experiencers are not distressed or regulating their emotional responses. In particular, experiencers showed less cognitive impairment on a Stroop task than forecasters. Together these findings indicate that when people actually encounter outgroup bias, they respond with apathy and do not censure the racist. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Evidence for ammonium-bearing minerals in Ceres

NASA Technical Reports Server (NTRS)

King, T. V. V.; Clark, R. N.; Calvin, W. M.; Sherman, D. M.; Swayze, G. A.; Brown, R. H.

1991-01-01

Evidence for ammonium-bearing minerals was found on the surface of the largest asteroid Ceres. The presence of ammonium-bearing clays suggests that Ceres has experienced a period of alteration by substantial amounts of an ammonium-bearing fluid. The presence of the ammonium-bearing clays does not preclude Ceres maintaining a volatile inventory in the core or in a volatile-rich zone at some distance below the surface. Telescopic observations of Ceres, using the 3.0 meter NASA Infrared telescope facility prompted this reevaluation of its surface mineralogy.

Burgers approximation for two-dimensional flow past an ellipse

NASA Technical Reports Server (NTRS)

Dorrepaal, J. M.

1982-01-01

A motivation is given for studying Burgers flow and a solution technique is outlined which works equally well for Oseen or Burgers flow past a circular cylinder. The separation behind the cylinder, the drag experienced by the cylinder, and asymptotic behavior far from the cylinder are described. It is shown that the predictions of Burgers flow near the cylinder provide a substantial improvement over those of Oseen flow. Finally, the equations of motion for Burgers flow past an ellipse are formulated and solved.

Parent-Body Modification of Chondritic Meteorites

NASA Technical Reports Server (NTRS)

Rubin, Alan

2003-01-01

This proposal focused on the parent-body modification of chondritic materials and substantial progress was made in the last year. A summary of the work accomplished during this period is discussed. The topics include: 1) Chromite-Plagioclase Assemblages in Ordinary Chondrites; 2) The Gujba Bencubbin-like meteorite fall; 3) NWA428: A rock that Experienced Impact-induced Annealing; 4) Spade: An Annealed H-chondrite Impact-melt Breccia; and 5) Post-shock Annealing in Ordinary Chondrites. A list of the papers submitted or published during the period is also presented.

The financial performance of hospitals belonging to health networks and systems.

PubMed

Bazzoli, G J; Chan, B; Shortell, S M; D'Aunno, T

2000-01-01

The U.S. health industry is experiencing substantial restructuring through ownership consolidation and development of new forms of interorganizational relationships. Using an established taxonomy of health networks and systems, this paper develops and tests four hypotheses related to hospital financial performance. Consistent with our predictions, we find that hospitals in health systems that had unified ownership generally had better financial performance than hospitals in contractually based health networks. Among health network hospitals, those belonging to highly centralized networks had better financial performance than those belonging to more decentralized networks. However, health system hospitals in moderately centralized systems performed better than those in highly centralized systems. Finally, hospitals in networks or systems with little differentiation or centralization experienced the poorest financial performance. These results are consistent with resource dependence, transaction cost economics, and institutional theories of organizational behavior, and provide a conceptual and empirical baseline for future research.

Fatigue in neuromuscular disorders: focus on Guillain-Barré syndrome and Pompe disease.

PubMed

de Vries, J M; Hagemans, M L C; Bussmann, J B J; van der Ploeg, A T; van Doorn, P A

2010-03-01

Fatigue accounts for an important part of the burden experienced by patients with neuromuscular disorders. Substantial high prevalence rates of fatigue are reported in a wide range of neuromuscular disorders, such as Guillain-Barré syndrome and Pompe disease. Fatigue can be subdivided into experienced fatigue and physiological fatigue. Physiological fatigue in turn can be of central or peripheral origin. Peripheral fatigue is an important contributor to fatigue in neuromuscular disorders, but in reaction to neuromuscular disease fatigue of central origin can be an important protective mechanism to restrict further damage. In most cases, severity of fatigue seems to be related with disease severity, possibly with the exception of fatigue occurring in a monophasic disorder like Guillain-Barré syndrome. Treatment of fatigue in neuromuscular disease starts with symptomatic treatment of the underlying disease. When symptoms of fatigue persist, non-pharmacological interventions, such as exercise and cognitive behavioral therapy, can be initiated.

Dl-phenylalanine in depressed patients: an open study.

PubMed

Beckmann, H; Strauss, M A; Ludolph, E

1977-01-01

In an open study dl-phenylalanine in doses from 75-200 mg/day was administered to 20 depressed patients for 20 days. Patients were classified according to the International Classification of Diseases (ICD). The AMP system, the Hamilton depression scale and the von Zerssen self rating questionnaire were used for documentation of psychopathological, neurologic and somatic changes. In addition a global clinical impression was agreed upon by experienced psychiatrists. At the end of the trial 12 patients (8 with complete, 4 with good response) could be discharged without any further treatment. 4 patients with partially untypical depressions experienced mild to moderate responses, whereas 4 patients did not respond at all to the phenylalanine administration. Depressive "core symptoms" as depressed mood, retardation and/or agitation were preferentially, anxiety and sleep disturbances moderately and hypochondriasis and compulsiveness were not influenced. It is concluded that dl-phenylalanine might have substantial antidepressant properties and that further more controlled investigations are warranted.

Impacts of fire on nitrogen cycling in aquatic and terrestrial ecosystems in the Yukon-Kuskokwim River Delta, AK

NASA Astrophysics Data System (ADS)

Schade, J. D.; Jardine, L. E.; Bristol, E. M.; Navarro-Perez, E.; Melton, S.; Jimmie, J. A.; Natali, S.; Mann, P. J.; Holmes, R. M.

2016-12-01

Global climate change is having a disproportionate impact on northern high latitudes, including rapid increases in temperature, changes in precipitation, and increasing fire frequency and severity. Wildfires have been shown to strongly influence ecosystem processes through acceleration of permafrost thaw and increased nitrogen (N) availability, the effects of which may increase gaseous loss of carbon (C) to the atmosphere, increase primary production by alleviating N limitation, or both. The extent of these fire impacts has not been well-documented in the Arctic, particularly in areas of discontinuous permafrost. In 2015, the Yukon-Kuskokwim River Delta (YK Delta) in southwestern Alaska experienced the largest fire season in recorded history, providing an opportunity to study wildfire impacts on an area particularly vulnerable to permafrost thaw. Our objectives were to study the impacts of these fires on nitrogen availability in a range of land cover classes, including peat plateaus, channel fens, and aquatic ecosystems distributed across the landscapes. We sampled soils from several vegetation patches on burned and unburned peat plateaus, and soil and surface waters from fens, small ponds, and streams downslope of these sites. All water samples were filtered through GFF filters in the field. Soils were transported frozen to the Woods Hole Research Center and extracted in KCl. All water samples and extracts were analyzed for NH4 and NO3 concentrations. We found substantially higher concentrations of extractable NH4 in burned soils, but very little extractable NO3 in either burned or unburned soils. Water samples also showed higher NH4 in aquatic ecosystems in burned watersheds, but, in contrast to soils, showed relatively high NO3 concentrations, particularly in waters from lower landscape positions. Overall, aquatic ecosystems exhibited higher NO3: NH4 ratios than soil extractions, and increasing NO3: NH4 downslope. These results suggest significant export of nitrogen after fire and the potential for nitrification as N is transported across the landscape. These changes in N cycling are likely to have substantial consequences for the recovery of plant communities post-fire and for microbial processes and greenhouse gas fluxes, including N2O, from burned watersheds.

Impacts of fire on nitrogen cycling in aquatic and terrestrial ecosystems in the Yukon-Kuskokwim River Delta, AK

NASA Astrophysics Data System (ADS)

Schade, J. D.; Jardine, L. E.; Bristol, E. M.; Navarro-Perez, E.; Melton, S.; Jimmie, J. A.; Natali, S.; Mann, P. J.; Holmes, R. M.

2017-12-01

Global climate change is having a disproportionate impact on northern high latitudes, including rapid increases in temperature, changes in precipitation, and increasing fire frequency and severity. Wildfires have been shown to strongly influence ecosystem processes through acceleration of permafrost thaw and increased nitrogen (N) availability, the effects of which may increase gaseous loss of carbon (C) to the atmosphere, increase primary production by alleviating N limitation, or both. The extent of these fire impacts has not been well-documented in the Arctic, particularly in areas of discontinuous permafrost. In 2015, the Yukon-Kuskokwim River Delta (YK Delta) in southwestern Alaska experienced the largest fire season in recorded history, providing an opportunity to study wildfire impacts on an area particularly vulnerable to permafrost thaw. Our objectives were to study the impacts of these fires on nitrogen availability in a range of land cover classes, including peat plateaus, channel fens, and aquatic ecosystems distributed across the landscapes. We sampled soils from several vegetation patches on burned and unburned peat plateaus, and soil and surface waters from fens, small ponds, and streams downslope of these sites. All water samples were filtered through GFF filters in the field. Soils were transported frozen to the Woods Hole Research Center and extracted in KCl. All water samples and extracts were analyzed for NH4 and NO3 concentrations. We found substantially higher concentrations of extractable NH4 in burned soils, but very little extractable NO3 in either burned or unburned soils. Water samples also showed higher NH4 in aquatic ecosystems in burned watersheds, but, in contrast to soils, showed relatively high NO3 concentrations, particularly in waters from lower landscape positions. Overall, aquatic ecosystems exhibited higher NO3: NH4 ratios than soil extractions, and increasing NO3: NH4 downslope. These results suggest significant export of nitrogen after fire and the potential for nitrification as N is transported across the landscape. These changes in N cycling are likely to have substantial consequences for the recovery of plant communities post-fire and for microbial processes and greenhouse gas fluxes, including N2O, from burned watersheds.

Impact of Competing Risk of Mortality on Association of Weight Loss with Risk of Central Body Fractures in Older Men: A Prospective Cohort Study

PubMed Central

Ensrud, Kristine E.; Harrison, Stephanie L.; Cauley, Jane A.; Langsetmo, Lisa; Schousboe, John T.; Kado, Deborah M.; Gourlay, Margaret L.; Lyons, Jennifer G.; Fredman, Lisa; Napoli, Nicolas; Crandall, Carolyn J.; Lewis, Cora E.; Orwoll, Eric S.; Stefanick, Marcia L.; Cawthon, Peggy M.

2017-01-01

To determine the association of weight loss with risk of clinical fractures at the hip, spine and pelvis (central body fractures [CBF]) in older men with and without accounting for the competing risk of mortality, we used data from 4,523 men (mean age 77.5 years). Weight change between baseline and follow-up (mean 4.5 years between examinations) was categorized as moderate loss (loss ≥10%), mild loss (loss 5% to <10%), stable (<5% change) or gain (gain ≥5%). Participants were contacted every 4 months after the follow-up examination to ascertain vital status (deaths verified by death certificates) and ask about fractures (confirmed by radiographic reports). Absolute probability of CBF by weight change category was estimated using traditional Kaplan-Meier method and cumulative incidence function accounting for competing mortality risk. Risk of CBF by weight change category was determined using conventional Cox proportional hazards regression and subdistribution hazards models with death as a competing risk. During an average of 8 years, 337 men (7.5%) experienced CBF and 1,569 (34.7%) died before experiencing this outcome. Among men with moderate weight loss, CBF probability was 6.8% at 5 years and 16.9% at 10 years using Kaplan-Meier vs. 5.7% at 5 years and 10.2% at 10 years using a competing risk approach. Men with moderate weight loss compared with those with stable weight had a 1.6-fold higher adjusted risk of CBF (HR 1.59, 95% CI 1.06–2.38) using Cox models that was substantially attenuated in models accounting for competing mortality risk and no longer significant (subdistribution HR 1.16, 95% CI 0.77–1.75). Results were similar in analyses substituting hip fracture for CBF. Older men with weight loss who survive are at increased risk of CBF, including hip fracture. However, ignoring the competing mortality risk among men with weight loss substantially overestimates their longterm fracture probability and relative fracture risk. PMID:27739103

Impact of Competing Risk of Mortality on Association of Weight Loss With Risk of Central Body Fractures in Older Men: A Prospective Cohort Study.

PubMed

Ensrud, Kristine E; Harrison, Stephanie L; Cauley, Jane A; Langsetmo, Lisa; Schousboe, John T; Kado, Deborah M; Gourlay, Margaret L; Lyons, Jennifer G; Fredman, Lisa; Napoli, Nicolas; Crandall, Carolyn J; Lewis, Cora E; Orwoll, Eric S; Stefanick, Marcia L; Cawthon, Peggy M

2017-03-01

To determine the association of weight loss with risk of clinical fractures at the hip, spine, and pelvis (central body fractures [CBFs]) in older men with and without accounting for the competing risk of mortality, we used data from 4523 men (mean age 77.5 years). Weight change between baseline and follow-up (mean 4.5 years between examinations) was categorized as moderate loss (loss ≥10%), mild loss (loss 5% to <10%), stable (<5% change) or gain (gain ≥5%). Participants were contacted every 4 months after the follow-up examination to ascertain vital status (deaths verified by death certificates) and ask about fractures (confirmed by radiographic reports). Absolute probability of CBF by weight change category was estimated using traditional Kaplan-Meier method and cumulative incidence function accounting for competing mortality risk. Risk of CBF by weight change category was determined using conventional Cox proportional hazards regression and subdistribution hazards models with death as a competing risk. During an average of 8 years, 337 men (7.5%) experienced CBF and 1569 (34.7%) died before experiencing this outcome. Among men with moderate weight loss, CBF probability was 6.8% at 5 years and 16.9% at 10 years using Kaplan-Meier versus 5.7% at 5 years and 10.2% at 10 years using a competing risk approach. Men with moderate weight loss compared with those with stable weight had a 1.6-fold higher adjusted risk of CBF (HR 1.59; 95% CI, 1.06 to 2.38) using Cox models that was substantially attenuated in models accounting for competing mortality risk and no longer significant (subdistribution HR 1.16; 95% CI, 0.77 to 1.75). Results were similar in analyses substituting hip fracture for CBF. Older men with weight loss who survive are at increased risk of CBF, including hip fracture. However, ignoring the competing mortality risk among men with weight loss substantially overestimates their long-term fracture probability and relative fracture risk. © 2016 American Society for Bone and Mineral Research. © 2016 American Society for Bone and Mineral Research.

100 years of STIs in the UK: a review of national surveillance data.

PubMed

Mohammed, Hamish; Blomquist, Paula; Ogaz, Dana; Duffell, Stephen; Furegato, Martina; Checchi, Marta; Irvine, Neil; Wallace, Lesley A; Thomas, Daniel Rhys; Nardone, Anthony; Dunbar, J Kevin; Hughes, Gwenda

2018-04-13

The 1916 Royal Commission on Venereal Diseases was established in response to epidemics of syphilis and gonorrhoea in the UK. In the 100 years since the Venereal Diseases Act (1917), the UK has experienced substantial scientific, economic and demographic changes. We describe historical and recent trends in STIs in the UK. We analysed surveillance data derived from STI clinics' statistical returns from 1917 to 2016. Since 1918, gonorrhoea and syphilis diagnoses have fluctuated, reflecting social, economic and technological trends. Following spikes after World Wars I and II, rates declined before re-emerging during the 1960s. At that time, syphilis was more common in men, suggestive of transmission within the men who have sex with men (MSM) population. Behaviour change following the emergence of HIV/AIDS in the 1980s is thought to have facilitated a precipitous decline in diagnoses of both STIs in the mid-1980s. Since the early 2000s, gonorrhoea and syphilis have re-emerged as major public health concerns due to increased transmission among MSM and the spread of antimicrobial-resistant gonorrhoea. Chlamydia and genital warts are now the most commonly diagnosed STIs in the UK and have been the focus of public health interventions, including the national human papillomavirus vaccination programme, which has led to substantial declines in genital warts in young people, and the National Chlamydia Screening Programme in England. Since the 1980s, MSM, black ethnic minorities and young people have experienced the highest STI rates. Although diagnoses have fluctuated over the last century, STIs continue to be an important public health concern, often affecting more marginalised groups in society. Prevention must remain a public health priority and, as we enter a new era of sexual healthcare provision including online services, priority must be placed on maintaining prompt access for those at greatest risk of STIs. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

A comparison of freezing-damage during isochoric and isobaric freezing of the potato.

PubMed

Lyu, Chenang; Nastase, Gabriel; Ukpai, Gideon; Serban, Alexandru; Rubinsky, Boris

2017-01-01

Freezing is commonly used for food preservation. It is usually done under constant atmospheric pressure (isobaric). While extending the life of the produce, isobaric freezing has detrimental effects. It causes loss of food weight and changes in food quality. Using thermodynamic analysis, we have developed a theoretical model of the process of freezing in a constant volume system (isochoric). The mathematical model suggests that the detrimental effects associated with isobaric freezing may be reduced in an isochoric freezing system. To explore this hypothesis, we performed a preliminary study on the isochoric freezing of a produce with which our group has experience, the potato. Experiments were performed in an isochoric freezing device we designed. The device is robust and has no moving parts. For comparison, we used a geometrically identical isobaric freezing device. Following freezing and thawing, the samples were weighed, examined with colorimetry, and examined with microscopy. It was found that potatoes frozen to -5 °C in an isochoric system experienced no weight loss and limited enzymatic browning. In contrast the -5 °C isobaric frozen potato experienced substantial weight loss and substantial enzymatic browning. Microscopic analysis shows that the structural integrity of the potato is maintained after freezing in the isochoric system and impaired after freezing in the isobaric system. Tissue damage during isobaric freezing is caused by the increase in extracellular osmolality and the mechanical damage by ice crystals. Our thermodynamic analysis predicts that during isochoric freezing the intracellular osmolality remains comparable to the extracellular osmolality and that isochoric systems can be designed to eliminate the mechanical damage by ice. The results of this preliminary study seem to confirm the theoretical predictions. This is a preliminary exploratory study on isochoric freezing of food. We have shown that the quality of a food product preserved by isochoric freezing is better than the quality of food preserved to the same temperature in isobaric conditions. Obviously, more extensive research remains to be done to extend this study to lower freezing temperatures and other food items.

A comparison of freezing-damage during isochoric and isobaric freezing of the potato

PubMed Central

Serban, Alexandru; Rubinsky, Boris

2017-01-01

Background Freezing is commonly used for food preservation. It is usually done under constant atmospheric pressure (isobaric). While extending the life of the produce, isobaric freezing has detrimental effects. It causes loss of food weight and changes in food quality. Using thermodynamic analysis, we have developed a theoretical model of the process of freezing in a constant volume system (isochoric). The mathematical model suggests that the detrimental effects associated with isobaric freezing may be reduced in an isochoric freezing system. To explore this hypothesis, we performed a preliminary study on the isochoric freezing of a produce with which our group has experience, the potato. Method Experiments were performed in an isochoric freezing device we designed. The device is robust and has no moving parts. For comparison, we used a geometrically identical isobaric freezing device. Following freezing and thawing, the samples were weighed, examined with colorimetry, and examined with microscopy. Results It was found that potatoes frozen to −5 °C in an isochoric system experienced no weight loss and limited enzymatic browning. In contrast the −5 °C isobaric frozen potato experienced substantial weight loss and substantial enzymatic browning. Microscopic analysis shows that the structural integrity of the potato is maintained after freezing in the isochoric system and impaired after freezing in the isobaric system. Discussion Tissue damage during isobaric freezing is caused by the increase in extracellular osmolality and the mechanical damage by ice crystals. Our thermodynamic analysis predicts that during isochoric freezing the intracellular osmolality remains comparable to the extracellular osmolality and that isochoric systems can be designed to eliminate the mechanical damage by ice. The results of this preliminary study seem to confirm the theoretical predictions. Conclusion This is a preliminary exploratory study on isochoric freezing of food. We have shown that the quality of a food product preserved by isochoric freezing is better than the quality of food preserved to the same temperature in isobaric conditions. Obviously, more extensive research remains to be done to extend this study to lower freezing temperatures and other food items. PMID:28533970

Astigmatism induced by conventional spherical ablation after PRK and LASIK in myopia with astigmatism < 1.00 D.

PubMed

Christiansen, Steven M; Mifflin, Mark D; Edmonds, Jason N; Simpson, Rachel G; Moshirfar, Majid

2012-01-01

The purpose of this study was to evaluate surgically-induced astigmatism after spherical ablation in photorefractive keratectomy (PRK) and laser-assisted in situ keratomileusis (LASIK) for myopia with astigmatism < 1.00 D. The charts of patients undergoing spherical PRK or LASIK for the correction of myopia with minimal astigmatism of <1.00 D from 2002 to 2012 at the John A Moran Eye Center in Salt Lake City, UT, were retrospectively reviewed. Astigmatism was measured by manifest refraction. The final astigmatic refractive outcome at 6 months postoperatively was compared with the initial refraction by Alpins vector analysis. For PRK, average cylinder increased from 0.39 ± 0.25 (0.00-0.75) preoperatively to 0.55 ± 0.48 (0.00-1.75) postoperatively (P = 0.014), compared with an increase in LASIK eyes from 0.40 ± 0.27 (0.00-0.75) preoperatively to 0.52 ± 0.45 (0.00-2.00) postoperatively (P = 0.041). PRK eyes experienced an absolute value change in cylinder of 0.41 ± 0.32 (0.00-1.50) and LASIK eyes experienced a change of 0.41 ± 0.31 (0.00-1.50, P = 0.955). Mean surgically-induced astigmatism was 0.59 ± 0.35 (0.00-1.70) in PRK eyes, with an increase in surgically-induced astigmatism of 0.44 D for each additional 1.00 D of preoperative cylinder; in LASIK eyes, mean surgically-induced astigmatism was 0.55 ± 0.32 (0.00-1.80, P = 0.482), with an increase in surgically-induced astigmatism of 0.29 D for each 1.00 D of preoperative cylinder. Spherical ablation can induce substantial astigmatism even in eyes with less than one diopter of preoperative astigmatism in both PRK and LASIK. No significant difference in the magnitude of surgically-induced astigmatism was found between eyes treated with PRK and LASIK, although surgically-induced astigmatism was found to increase with greater levels of preoperative astigmatism in both PRK and LASIK.

Astigmatism induced by conventional spherical ablation after PRK and LASIK in myopia with astigmatism < 1.00 D

PubMed Central

Christiansen, Steven M; Mifflin, Mark D; Edmonds, Jason N; Simpson, Rachel G; Moshirfar, Majid

2012-01-01

Background The purpose of this study was to evaluate surgically-induced astigmatism after spherical ablation in photorefractive keratectomy (PRK) and laser-assisted in situ keratomileusis (LASIK) for myopia with astigmatism < 1.00 D. Methods The charts of patients undergoing spherical PRK or LASIK for the correction of myopia with minimal astigmatism of <1.00 D from 2002 to 2012 at the John A Moran Eye Center in Salt Lake City, UT, were retrospectively reviewed. Astigmatism was measured by manifest refraction. The final astigmatic refractive outcome at 6 months postoperatively was compared with the initial refraction by Alpins vector analysis. Results For PRK, average cylinder increased from 0.39 ± 0.25 (0.00–0.75) preoperatively to 0.55 ± 0.48 (0.00–1.75) postoperatively (P = 0.014), compared with an increase in LASIK eyes from 0.40 ± 0.27 (0.00–0.75) preoperatively to 0.52 ± 0.45 (0.00–2.00) postoperatively (P = 0.041). PRK eyes experienced an absolute value change in cylinder of 0.41 ± 0.32 (0.00–1.50) and LASIK eyes experienced a change of 0.41 ± 0.31 (0.00–1.50, P = 0.955). Mean surgically-induced astigmatism was 0.59 ± 0.35 (0.00–1.70) in PRK eyes, with an increase in surgically-induced astigmatism of 0.44 D for each additional 1.00 D of preoperative cylinder; in LASIK eyes, mean surgically-induced astigmatism was 0.55 ± 0.32 (0.00–1.80, P = 0.482), with an increase in surgically-induced astigmatism of 0.29 D for each 1.00 D of preoperative cylinder. Conclusion Spherical ablation can induce substantial astigmatism even in eyes with less than one diopter of preoperative astigmatism in both PRK and LASIK. No significant difference in the magnitude of surgically-induced astigmatism was found between eyes treated with PRK and LASIK, although surgically-induced astigmatism was found to increase with greater levels of preoperative astigmatism in both PRK and LASIK. PMID:23277735

Predictors of Hospitalization among Children on ART in Ethiopia: a Cohort study.

PubMed

Haileamlak, Abraham; Hagos, Tesfalem; Abebe, Workeabeba; Abraham, Loko; Asefa, Henok; Teklu, Alula M

2017-02-01

Substantial progress has been made in the management of pediatric HIV infection in Ethiopia with the implementation of mother-to-child-prevention programs. Since the introduction of HAART in 2005, mortality among HIV-infected children has reduced while the rate of hospitalization was expected to rise. The purpose of this study, therefore, was to assess predictors of hospitalization in children on ART in seven university referral hospitals in Ethiopia. A prospective cohort study design was employed on children age 0-18 years as part of a multisite observational study. ART-experienced eligible and ART-naïve children with HIV/AIDS were enrolled into the Advanced Clinical Monitoring (ACM) till December 31, 2012 were included. From the database, information on hospitalization and other independent variables were extracted. Analysis was done using both SPSS for Windows version 16.0 and STATA. Descriptive analyses and modeling was done using logistic regression. Of the 405 children on ART (174 experienced, 231 naive), 86 (20.7%) were hospitalized for various reasons; two children were excluded since they were hospitalized for unrelated conditions (appendicitis and burn). Fifty one (60.7%) of the eighty four admitted children were hospitalized in the first six months of ART initiation. Of the independent variables, only the presence of opportunistic infections and duration on ART were significantly associated with hospitalization both on bi-variable and multivariable analyses (P-value <0.05). As the duration on ART increased by one month, the risk of hospitalization decreased by 5.4%, which is statistically significant (P < 0.001). Whereas the incidence (number) of OI's increased by one, the risk of being hospitalized increased by 35.2% (P = 0.002). Of the individual opportunistic infections, pneumonia was found to be the only predictor of hospitalization (P-value = 0.002). This study showed that nearly two-third of the hospitalization was within 6 months of initiation of ART; and presence of OI and duration on ART were the only predictors of hospitalization.

Water- and sediment-quality effects on Pimephales promelas spawning vary along an agriculture-to-urban land-use gradient.

PubMed

Corsi, Steven R; Klaper, Rebecca D; Weber, Daniel N; Bannerman, Roger T

2011-10-15

Many streams in the U.S. are "impaired" due to anthropogenic influence. For watershed managers to achieve practical understanding of these impairments, a multitude of factors must be considered, including point and nonpoint-source influence on water quality. A spawning assay was developed in this study to evaluate water- and sediment-quality effects that influenced Pimephales promelas (fathead minnow) egg production over a gradient of urban and agricultural land use in 27 small watersheds in Eastern Wisconsin. Six pairs of reproducing fathead minnows were contained in separate mesh cartridges within one larger flow-through chamber. Water- and sediment quality were sampled for an array of parameters. Egg production was monitored for each pair providing an assessment of spawning success throughout the 21-day test periods. Incidences of low dissolved oxygen (DO) in many of these streams negatively impacted spawning success. Nine of 27 streams experienced DO less than 3.1mg/L and 15 streams experienced DO less than 4.8mg/L. Low DO was observed in urban and agricultural watersheds, but the upper threshold of minimum DO decreased with increasing urban development. An increase in specific conductance was related to a decrease in spawning success. In previous studies for streams in this region, specific conductance had a linear relation with chloride, suggesting the possibility that chloride could be a factor in egg production. Egg production was lower at sites with substantial urban development, but sites with low egg production were not limited to urban sites. Degradation of water- and sediment-quality parameters with increasing urban development is indicated for multiple parameters while patterns were not detected for others. Results from this study indicate that DO must be a high priority watershed management consideration for this region, specific conductance should be investigated further to determine the mechanism of the relation with egg production, and water- and sediment-quality degrade in relation to urban influence. Published by Elsevier B.V.

Water- and sediment-quality effects on Pimephales promelas spawning vary along an agriculture-to-urban land-use gradient

USGS Publications Warehouse

Corsi, S.R.; Klaper, R.D.; Weber, D.N.; Bannerman, R.T.

2011-01-01

Many streams in the U.S. are "impaired" due to anthropogenic influence. For watershed managers to achieve practical understanding of these impairments, a multitude of factors must be considered, including point and nonpoint-source influence on water quality. A spawning assay was developed in this study to evaluate water- and sediment-quality effects that influenced Pimephales promelas (fathead minnow) egg production over a gradient of urban and agricultural land use in 27 small watersheds in Eastern Wisconsin. Six pairs of reproducing fathead minnows were contained in separate mesh cartridges within one larger flow-through chamber. Water- and sediment quality were sampled for an array of parameters. Egg production was monitored for each pair providing an assessment of spawning success throughout the 21-day test periods. Incidences of low dissolved oxygen (DO) in many of these streams negatively impacted spawning success. Nine of 27 streams experienced DO less than 3.1. mg/L and 15 streams experienced DO less than 4.8. mg/L. Low DO was observed in urban and agricultural watersheds, but the upper threshold of minimum DO decreased with increasing urban development. An increase in specific conductance was related to a decrease in spawning success. In previous studies for streams in this region, specific conductance had a linear relation with chloride, suggesting the possibility that chloride could be a factor in egg production. Egg production was lower at sites with substantial urban development, but sites with low egg production were not limited to urban sites. Degradation of water- and sediment-quality parameters with increasing urban development is indicated for multiple parameters while patterns were not detected for others. Results from this study indicate that DO must be a high priority watershed management consideration for this region, specific conductance should be investigated further to determine the mechanism of the relation with egg production, and water- and sediment-quality degrade in relation to urban influence. ?? 2011.

Occupancy patterns of regionally declining grassland sparrow populations in a forested Pennsylvania landscape

USGS Publications Warehouse

Hill, Jason M.; Diefenbach, Duane R.

2014-01-01

Organisms can be affected by processes in the surrounding landscape outside the boundary of habitat areas and by local vegetation characteristics. There is substantial interest in understanding how these processes affect populations of grassland birds, which have experienced substantial population declines. Much of our knowledge regarding patterns of occupancy and density stem from prairie systems, whereas relatively little is known regarding how occurrence and abundance of grassland birds vary in reclaimed surface mine grasslands. Using distance sampling and single-season occupancy models, we investigated how the occupancy probability of Grasshopper (Ammodramus savannarum) and Henslow's Sparrows (A. henslowii) on 61 surface mine grasslands (1591 ha) in Pennsylvania changed from 2002 through 2011 in response to landscape, grassland, and local vegetation characteristics . A subset (n = 23; 784 ha) of those grasslands were surveyed in 2002, and we estimated changes in sparrow density and vegetation across 10 years. Grasshopper and Henslow's Sparrow populations declined 72% and 49%, respectively from 2002 to 2011, whereas overall woody vegetation density increased 2.6 fold. Henslow's Sparrows avoided grasslands with perimeter–area ratios ≥0.141 km/ha and woody shrub densities ≥0.04 shrubs/m2. Both species occupied grasslands ≤13 ha, but occupancy probability declined with increasing grassland perimeter–area ratio and woody shrub density. Grassland size, proximity to nearest neighboring grassland ( = 0.2 km), and surrounding landscape composition at 0.5, 1.5, and 3.0 km were not parsimonious predictors of occupancy probability for either species. Our results suggest that reclaimed surface mine grasslands, without management intervention, are ephemeral habitats for Grasshopper and Henslow's Sparrows. Given the forecasted decline in surface coal production for Pennsylvania, it is likely that both species will continue to decline in our study region for the foreseeable future.

Changes in prevalence of workplace violence against doctors in all medical specialties in Norway between 1993 and 2014: a repeated cross-sectional survey

PubMed Central

Johansen, Ingrid Hjulstad; Baste, Valborg; Rosta, Judith; Aasland, Olaf G; Morken, Tone

2017-01-01

Objectives The aim of this study was to investigate whether reported prevalence of experienced threats, real acts of violence and debilitating fear of violence among Norwegian doctors have increased over the last two decades. Design Repeated cross-sectional survey. Setting All healthcare levels and medical specialties in Norway. Participants Representative samples of Norwegian doctors in 1993 (n=2628) and 2014 (n=1158). Main outcome measures Relative risk (RR) of self-reported prevalence of work-time experiences of threats and real acts of violence, and of being physically or psychologically unfit during the last 12 months due to fear of violence, in 2014 compared with 1993, adjusted by age, gender and medical specialty. Results There were no differences in self-reported threats (adjusted RR=1.01, 95% CI 0.95 to 1.08) or real acts (adjusted RR=0.90, 95% CI 0.80 to 1.03) of violence when comparing 2014 with 1993. The proportion of doctors who had felt unfit due to fear of violence decreased from 1993 to 2014 (adjusted RR=0.53, 95% CI 0.39 to 0.73). Although still above average, the proportion of doctors in psychiatry who reported real acts of violence decreased substantially from 1993 to 2014 (adjusted RR=0.75, 95% CI 0.60 to 0.95). Conclusions A substantial proportion of doctors experience threats and real acts of violence during their work-time career, but there was no evidence that workplace violence has increased over the last two decades. Still, the issue needs to be addressed as part of the doctors’ education and within work settings. PMID:28801441

Work-home conflicts have a substantial impact on career decisions that affect the adequacy of the surgical workforce.

PubMed

Dyrbye, Liselotte N; Freischlag, Julie; Kaups, Krista L; Oreskovich, Michael R; Satele, Daniel V; Hanks, John B; Sloan, Jeff A; Balch, Charles M; Shanafelt, Tait D

2012-10-01

To evaluate factors associated with work-home conflicts (W-HCs) of US surgeons and their potential personal and professional consequences. Cross-sectional study. Members of the American College of Surgeons. Burnout, depression, quality of life, alcohol use, career satisfaction, and career decisions (ie, reduce work hours or leave current practice). Of 7197 participating surgeons, 3754 (52.5%) had experienced a W-HC in the previous 3 weeks. On multivariate analysis, hours worked per week, having children, sex, and work location (Veterans Administration or academic center) were independently associated with an increased risk for W-HC (all P < .01), while some factors (increased age and subspecialty field) reduced the risk. Surgeons with a recent W-HC were more likely to have symptoms of burnout (36.9% vs 17.1%; P < .001), depression (50.9% vs 28.1%; P < .001), alcohol abuse/dependency (17.2% vs 14.4%; P = .003), and were less likely to recommend surgery as a career option to their children (46.0% vs 54.4%; P < .001). Work-home conflicts were also independently associated with surgeons reporting a moderate or higher likelihood of planning to reduce clinical work hours (odds ratio, 1.769) and leave their current practice in the next 24 months for a reason other than retirement (odds ratio, 1.706) after controlling for other personal and professional factors. Integrating personal and professional lives is a substantial challenge for US surgeons. Conflict in this balance appears to be a major factor in their decision to reduce work hours and/or move to a new practice, with potential substantive manpower implications for the surgical workforce.

Contrasting hydraulic strategies in two tropical lianas and their host trees.

PubMed

Johnson, Daniel M; Domec, Jean-Christophe; Woodruff, David R; McCulloh, Katherine A; Meinzer, Frederick C

2013-02-01

Tropical liana abundance has been increasing over the past 40 yr, which has been associated with reduced rainfall. The proposed mechanism allowing lianas to thrive in dry conditions is deeper root systems than co-occurring trees, although we know very little about the fundamental hydraulic physiology of lianas. To test the hypothesis that two abundant liana species would physiologically outperform their host tree under reduced water availability, we measured rooting depth, hydraulic properties, plant water status, and leaf gas exchange during the dry season in a seasonally dry tropical forest. We also used a model to compare water use by one of the liana species and the host tree during drought. All species measured were shallowly rooted. The liana species were more vulnerable to embolism than host trees and experienced water potentials that were predicted to result in substantial hydraulic losses in both leaves and stems. Water potentials measured in host trees were not negative enough to result in significant hydraulic losses. Model results predicted the liana to have greater gas exchange than its host tree during drought and nondrought conditions. The host tree species had a more conservative strategy for maintenance of the soil-to-leaf hydraulic pathway than the lianas it supported. The two liana species experienced embolism in stems and leaves, based on vulnerability curves and water potentials. These emboli were presumably repaired before the next morning. However, in the host tree species, reduced stomatal conductance prevented leaf or stem embolism.

A dynamic seating intervention for wheelchair seating discomfort.

PubMed

Crane, Barbara A; Holm, Margo B; Hobson, Douglas; Cooper, Rory A; Reed, Matthew P

2007-12-01

The objective of this study was to examine the effectiveness of a new user-adjustable wheelchair seating system designed to relieve discomfort for long-duration wheelchair users. This objective was carried out using the newly developed Tool for Assessing Wheelchair disComfort (TAWC) as the primary outcome measure. Two wheelchair users each tested two different designs and feedback from the wheelchair users regarding the first design was used to guide development of the second design. A single-subject research methodology was used, allowing long-duration (up to 2 wks per test) evaluation of the wheelchair seating systems and comparison of subject discomfort levels with those experienced during a baseline period using their own wheelchairs. The experimental wheelchair seating systems employed existing automotive seating with embedded pneumatic bladders that allowed adjustment of the seat and back-support characteristics. The test wheelchair also had tilt, recline, and elevating leg rests. The two subjects completed limited periods of testing with the first design, both finding poor results with either stable or increased levels of discomfort. Subject feedback was used to redesign the wheelchair seat. After redesign, both subjects tested the second design and found it substantially more comfortable. The selected research methodology was a very positive method for a progressive wheelchair seating design and the second design provided improved comfort for both users when compared with that experienced using their own wheelchairs and the first test wheelchair. Future research of this type of user-controlled technology is recommended.

Immunotherapy in ovarian, endometrial and cervical cancer: State of the art and future perspectives.

PubMed

Ventriglia, Jole; Paciolla, Immacolata; Pisano, Carmela; Cecere, Sabrina Chiara; Di Napoli, Marilena; Tambaro, Rosa; Califano, Daniela; Losito, Simona; Scognamiglio, Giosuè; Setola, Sergio Venanzio; Arenare, Laura; Pignata, Sandro; Della Pepa, Chiara

2017-09-01

The tumors of the female genital tract represent a leading cause of morbidity and mortality among women worldwide. Substantial progresses have been made in ovarian cancer, with the increasing knowledge about BRCA mutated tumors and the recent development of PARP inhibitors, and in cervical cancer, thanks to extensive screening and widespread of vaccination against Human Papilloma Virus. Nevertheless many needs remain unmet, advanced stage diseases are still incurable and cervical and endometrial carcinoma, as well as platinum-resistant ovarian carcinoma, can certainly be classifiable among the cancers with poor sensitivity to conventional chemotherapy. Immunotherapy, including a number of approaches, checkpoint inhibitors, adoptive cellular transfer, vaccines, has experienced a remarkable growth in the last few years and it is already an available option in melanoma, lung and renal malignancies. We reviewed the main findings about the immune microenvironment in ovarian, endometrial and cervical cancer with a special focus on the clinical data, the therapeutic implications and the most promising novel agents. Copyright © 2017 Elsevier Ltd. All rights reserved.

`Been There Done That': Disentangling Option Value Effects from User Heterogeneity When Valuing Natural Resources with a Use Component

NASA Astrophysics Data System (ADS)

Lyssenko, Nikita; Martínez-Espiñeira, Roberto

2012-11-01

Endogeneity bias arises in contingent valuation studies when the error term in the willingness to pay (WTP) equation is correlated with explanatory variables because observable and unobservable characteristics of the respondents affect both their WTP and the value of those variables. We correct for the endogeneity of variables that capture previous experience with the resource valued, humpback whales, and with the geographic area of study. We consider several endogenous behavioral variables. Therefore, we apply a multivariate Probit approach to jointly model them with WTP. In this case, correcting for endogeneity increases econometric efficiency and substantially corrects the bias affecting the estimated coefficients of the experience variables, by isolating the decreasing effect on option value caused by having already experienced the resource. Stark differences are unveiled between the marginal effects on WTP of previous experience of the resource in an alternative location versus experience in the location studied, Newfoundland and Labrador (Canada).

'Been there done that': disentangling option value effects from user heterogeneity when valuing natural resources with a use component.

PubMed

Lyssenko, Nikita; Martínez-Espiñeira, Roberto

2012-11-01

Endogeneity bias arises in contingent valuation studies when the error term in the willingness to pay (WTP) equation is correlated with explanatory variables because observable and unobservable characteristics of the respondents affect both their WTP and the value of those variables. We correct for the endogeneity of variables that capture previous experience with the resource valued, humpback whales, and with the geographic area of study. We consider several endogenous behavioral variables. Therefore, we apply a multivariate Probit approach to jointly model them with WTP. In this case, correcting for endogeneity increases econometric efficiency and substantially corrects the bias affecting the estimated coefficients of the experience variables, by isolating the decreasing effect on option value caused by having already experienced the resource. Stark differences are unveiled between the marginal effects on WTP of previous experience of the resource in an alternative location versus experience in the location studied, Newfoundland and Labrador (Canada).

Detection and attribution of flood change across the United States

NASA Astrophysics Data System (ADS)

Archfield, Stacey

2017-04-01

In the United States, there have a been an increasing number of studies quantifying trends in the annual maximum flood; yet, few studies examine trends in floods that may occur more than once in a given year and even fewer assess trends in floods on rivers that have undergone substantial changes due to urbanization, land-cover change, and agricultural drainage practices. Previous research has shown that, for streamgages having minimal direct human intervention, trends in the peak magnitude, frequency, duration and volume of frequent floods (floods occurring at an average of two events per year relative to a base period) across the United States show large changes; however, few trends are found to be statistically significant. This study extends previous research to provide a comprehensive assessment of flood change across the United States that includes streamgages having experienced confounding alterations to streamflow (urbanization, storage, and land-cover changes) that provides a comprehensive assessment of flood change. Attribution of these changes is also explored.

Partial nitrification in an air-lift reactor with long-term feeding of increasing ammonium concentrations.

PubMed

Chai, Li-Yuan; Ali, Mohammad; Min, Xiao-Bo; Song, Yu-Xia; Tang, Chong-Jian; Wang, Hai-Ying; Yu, Cheng; Yang, Zhi-Hui

2015-06-01

The partial nitrification (PN) performance under high ammonium concentrations was evaluated in an airlift reactor (ALR). The ALR was operated for 253days with stepwise elevation of ammonium concentration to 1400mg/L corresponding nitrogen loading rate of 2.1kg/m(3)/d. The ammonium removal rate was finally developed to 2.0kg/m(3)/d with average removal efficiency above 91% and nitrite accumulation percentage of 80%. Results showed that the combined effect of limited DO, high bicarbonate, pH and free ammonia (FA) contributed to the stable nitrite accumulation substantially. The biomass in the ALR was improved with the inception of granulation. Precipitates on biomass surface was unexpectedly experienced which might improve the settleability of PN biomass. Organic functional groups attached to the PN biomass suggested the possible absorbability to different types of pollutant. The results provided important evidence for the possibility of applying an ALR to treat high strength ammonium wastewater. Copyright © 2015 Elsevier Ltd. All rights reserved.

Beyond the Border and Into the Heartland: Spatial Patterning of U.S. Immigration Detention.

PubMed

Moinester, Margot

2018-06-01

The expansion of U.S. immigration enforcement from the borders into the interior of the country and the fivefold increase in immigration detentions and deportations since 1995 raise important questions about how the enforcement of immigration law is spatially patterned across American communities. Focusing on the practice of immigration detention, the present study analyzes the records of all 717,160 noncitizens detained by Immigration and Customs Enforcement (ICE) in 2008 and 2009-a period when interior enforcement was at its peak-to estimate states' detention rates and examine geographic variation in detention outcomes, net of individual characteristics. Findings reveal substantial state heterogeneity in immigration detention rates, which range from approximately 350 detentions per 100,000 noncitizens in Connecticut to more than 6,700 detentions per 100,000 noncitizens in Wyoming. After detainment, individuals' detention outcomes are geographically stratified, especially for detainees eligible for pretrial release. These disparities indicate the important role that geography plays in shaping individuals' chances of experiencing immigration detention and deportation.

A meta-analytic review of the association between cortisol reactivity in response to a stressor and attention-deficit hyperactivity disorder.

PubMed

Kamradt, Jaclyn M; Momany, Allison M; Nikolas, Molly A

2018-06-01

A substantial literature suggests that abnormal cortisol reactivity may be a vulnerability for deleterious mental health outcomes, including ADHD. ADHD has been linked with difficulty in emotion regulation and increased risk of experiencing stressors, both of which may be related to psychobiological abnormalities (e.g., abnormal cortisol reactivity). Research has been mixed regarding the association between cortisol reactivity and ADHD. Therefore, the present meta-analytic review (k = 12) sought to quantify this association and review the relevant methodological issues and theoretical implications of this area of research. Overall, no effect was found between cortisol reactivity and ADHD (r = 0), although significant heterogeneity in the analyses suggested that there might be moderators of this association, if one does exist. Results highlight the importance of addressing limitations of the current literature on cortisol reactivity and ADHD and exploring additional indices of emotion regulation that may be associated with ADHD. Implications for future research efforts are discussed.

A MIMIC approach to modeling the underground economy in Taiwan

NASA Astrophysics Data System (ADS)

Wang, David Han-Min; Lin, Jer-Yan; Yu, Tiffany Hui-Kuang

2006-11-01

The size of underground economy (UE) expansion usually increases the tax gap, impose a burden on the economy, and results in tax distortions. This study uses the MIMIC approach to model the causal variables and indicating variables to estimate the UE in Taiwan. We also focus on testing the data for non-stationarity and perform diagnostic tests. By using annual time-series data for Taiwan from 1961 to 2003, it is found that the estimated size of the UE varies from 11.0% to 13.1% before 1988, and from 10.6% to 11.8% from 1989 onwards. That the size of the UE experienced a substantial downward shift in 1989 indicates that there was a structural break. The UE is significantly and positively affected by such casual variables as the logarithm of real government consumption and currency inflation, but is negatively affected by the tax burden at 5% significant level. Unemployment rate and crime rate are not significantly correlated with the UE in this study.

A meta-analytic review of the association between cortisol reactivity in response to a stressor and attention-deficit hyperactivity disorder

PubMed Central

Momany, Allison M.; Nikolas, Molly A.

2017-01-01

A substantial literature suggests that abnormal cortisol reactivity may be a vulnerability for deleterious mental health outcomes, including ADHD. ADHD has been linked with difficulty in emotion regulation and increased risk of experiencing stressors, both of which may be related to psychobiological abnormalities (e.g., abnormal cortisol reactivity). Research has been mixed regarding the association between cortisol reactivity and ADHD. Therefore, the present meta-analytic review (k = 12) sought to quantify this association and review the relevant methodological issues and theoretical implications of this area of research. Overall, no effect was found between cortisol reactivity and ADHD (r = 0), although significant heterogeneity in the analyses suggested that there might be moderators of this association, if one does exist. Results highlight the importance of addressing limitations of the current literature on cortisol reactivity and ADHD and exploring additional indices of emotion regulation that may be associated with ADHD. Implications for future research efforts are discussed. PMID:28875432

Epidemiology of reflux symptoms and GORD.

PubMed

Ronkainen, Jukka; Agréus, Lars

2013-06-01

Gastro-oesophageal reflux disease (GORD) occurs when reflux of gastric contents causes troublesome symptoms and/or complications (the Montreal definition). GORD is a common condition with a substantial economical burden to the community and it has a significant negative effect on health-related quality of life (HRQoL) while endoscopic findings like erosive oesophagitis per se seem to correlate badly with the experienced HRQoL. The prevalence of GORD varies over the world for unknown reasons, but genetic differences, difference in the Helicobacter pylori prevalence and life style factors like obesity might influence. The prevalence is lowest in East Asia (2.5-9.4%) and higher in Mid (7.6-19.4%) and Western Asia (12.5-27.6%). The highest population-based prevalence is reported from Europe (23.7%) and the US (28.8%). GORD seems to be fairly stable over time both in terms of symptoms and erosive oesophagitis, but the prevalence seems to be increasing both in Asia and in the West. © 2013 Published by Elsevier Ltd.

Mitigation potential and global health impacts from emissions pricing of food commodities

NASA Astrophysics Data System (ADS)

Springmann, Marco; Mason-D'Croz, Daniel; Robinson, Sherman; Wiebe, Keith; Godfray, H. Charles J.; Rayner, Mike; Scarborough, Peter

2017-01-01

The projected rise in food-related greenhouse gas emissions could seriously impede efforts to limit global warming to acceptable levels. Despite that, food production and consumption have long been excluded from climate policies, in part due to concerns about the potential impact on food security. Using a coupled agriculture and health modelling framework, we show that the global climate change mitigation potential of emissions pricing of food commodities could be substantial, and that levying greenhouse gas taxes on food commodities could, if appropriately designed, be a health-promoting climate policy in high-income countries, as well as in most low- and middle-income countries. Sparing food groups known to be beneficial for health from taxation, selectively compensating for income losses associated with tax-related price increases, and using a portion of tax revenues for health promotion are potential policy options that could help avert most of the negative health impacts experienced by vulnerable groups, whilst still promoting changes towards diets which are more environmentally sustainable.

TECHNIQUES AND OUTCOMES OF MINIMALLY-INVASIVE TRABECULAR ABLATION AND BYPASS SURGERY

PubMed Central

Kaplowitz, Kevin; Schuman, Joel S.; Loewen, Nils A.

2014-01-01

Minimally invasive glaucoma surgeries (MIGS) can improve the conventional, pressure dependent outflow by bypassing or ablating the trabecular meshwork or create alternative drainage routes into the suprachoroidal or subconjunctival space. They have a highly favorable risk profile compared to penetrating surgeries and lower intraocular pressure with variable efficacy that may depend on the extent of outflow segments accessed. Since they are highly standardized procedures that use clear corneal incisions, they can elegantly be combined with cataract and refractive procedures to improve vision in the same session. There is a growing need for surgeons to become proficient in MIGS to address the increasing prevalence of glaucoma and cataracts in a well-informed, aging population. Techniques of visualization and instrumentation in an anatomically highly confined space with semi-transparent tissues are fundamentally different from other anterior segment surgeries and present even experienced surgeons with a substantial learning curve. Here, we provide practical tips and review techniques and outcomes of TM bypass and ablation MIGS. PMID:24338085

Neighborhood Racial Composition, Racial Discrimination, and Depressive Symptoms in African Americans

PubMed Central

Lambert, Sharon F.; Evans, Michele K.; Zonderman, Alan B.

2015-01-01

While evidence indicates that experienced racial discrimination is associated with increased depressive symptoms for African Americans, there is little research investigating predictors of experienced racial discrimination. This paper examines neighborhood racial composition and sociodemographic factors as antecedents to experienced racial discrimination and resultant levels of depressive symptoms among African American adults. The sample included 505 socioeconomically-diverse African American adults from Baltimore, MD. Study data were obtained via self-report and geocoding of participant addresses based on 2010 census data. Study hypotheses were tested using multiple pathways within a longitudinal Structural Equation Model. Experienced racial discrimination was positively associated with age and sex such that older individuals and males experienced increased levels of racial discrimination. In addition, the percentage of White individuals residing in a neighborhood was positively associated with levels of experienced racial discrimination for African American neighborhood residents. Experienced racial discrimination was positively associated with later depressive symptoms. Neighborhood-level contextual factors such as neighborhood racial composition and individual differences in sociodemographic characteristics appear to play an important role in the experience of racial discrimination and the etiology of depression in African American adults. PMID:24969707

Neighborhood racial composition, racial discrimination, and depressive symptoms in African Americans.

PubMed

English, Devin; Lambert, Sharon F; Evans, Michele K; Zonderman, Alan B

2014-12-01

While evidence indicates that experienced racial discrimination is associated with increased depressive symptoms for African Americans, there is little research investigating predictors of experienced racial discrimination. This paper examines neighborhood racial composition and sociodemographic factors as antecedents to experienced racial discrimination and resultant levels of depressive symptoms among African American adults. The sample included 505 socioeconomically-diverse African American adults from Baltimore, MD. Study data were obtained via self-report and geocoding of participant addresses based on 2010 census data. Study hypotheses were tested using multiple pathways within a longitudinal Structural Equation Model. Experienced racial discrimination was positively associated with age and sex such that older individuals and males experienced increased levels of racial discrimination. In addition, the percentage of White individuals residing in a neighborhood was positively associated with levels of experienced racial discrimination for African American neighborhood residents. Experienced racial discrimination was positively associated with later depressive symptoms. Neighborhood-level contextual factors such as neighborhood racial composition and individual differences in sociodemographic characteristics appear to play an important role in the experience of racial discrimination and the etiology of depression in African American adults.

Enhanced methane emissions from tropical wetlands during the 2011 La Niña

PubMed Central

Pandey, Sudhanshu; Houweling, Sander; Krol, Maarten; Aben, Ilse; Monteil, Guillaume; Nechita-Banda, Narcisa; Dlugokencky, Edward J.; Detmers, Rob; Hasekamp, Otto; Xu, Xiyan; Riley, William J.; Poulter, Benjamin; Zhang, Zhen; McDonald, Kyle C.; White, James W. C.; Bousquet, Philippe; Röckmann, Thomas

2017-01-01

Year-to-year variations in the atmospheric methane (CH4) growth rate show significant correlation with climatic drivers. The second half of 2010 and the first half of 2011 experienced the strongest La Niña since the early 1980s, when global surface networks started monitoring atmospheric CH4 mole fractions. We use these surface measurements, retrievals of column-averaged CH4 mole fractions from GOSAT, new wetland inundation estimates, and atmospheric δ13C-CH4 measurements to estimate the impact of this strong La Niña on the global atmospheric CH4 budget. By performing atmospheric inversions, we find evidence of an increase in tropical CH4 emissions of ∼6–9 TgCH4 yr−1 during this event. Stable isotope data suggest that biogenic sources are the cause of this emission increase. We find a simultaneous expansion of wetland area, driven by the excess precipitation over the Tropical continents during the La Niña. Two process-based wetland models predict increases in wetland area consistent with observationally-constrained values, but substantially smaller per-area CH4 emissions, highlighting the need for improvements in such models. Overall, tropical wetland emissions during the strong La Niña were at least by 5% larger than the long-term mean. PMID:28393869

Documented family violence and risk of suicide attempt among U.S. Army soldiers.

PubMed

Ursano, Robert J; Stein, Murray B; Herberman Mash, Holly B; Naifeh, James A; Fullerton, Carol S; Zaslavsky, Alan M; Ng, Tsz Hin Hinz; Aliaga, Pablo A; Wynn, Gary H; Dinh, Hieu M; McCarroll, James E; Sampson, Nancy A; Kao, Tzu-Cheg; Schoenbaum, Michael; Heeringa, Steven G; Kessler, Ronald C

2018-04-01

Suicide attempt (SA) rates in the U.S. Army increased substantially during the wars in Afghanistan and Iraq. This study examined associations of family violence (FV) history with SA risk among soldiers. Using administrative data from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS), we identified person-month records of active duty, Regular Army, enlisted soldiers with medically documented SAs from 2004 to 2009 (n = 9650) and a sample of control person-months (n = 153,528). Logistic regression analyses examined associations of FV with SA, adjusting for socio-demographics, service-related characteristics, and prior mental health diagnosis. Odds of SA were higher in soldiers with a FV history and increased as the number of FV events increased. Soldiers experiencing past-month FV were almost five times as likely to attempt suicide as those with no FV history. Odds of SA were elevated for both perpetrators and those who were exclusively victims. Male perpetrators had higher odds of SA than male victims, whereas female perpetrators and female victims did not differ in SA risk. A discrete-time hazard function indicated that SA risk was highest in the initial months following the first FV event. FV is an important consideration in understanding risk of SA among soldiers. Published by Elsevier B.V.

Childbearing across Partnerships in Australia, the United States, Norway and Sweden

PubMed Central

Thomson, Elizabeth; Lappegård, Trude; Carlson, Marcia; Evans, Ann; Gray, Edith

2017-01-01

This paper compares mothers’ experience of having children with more than one partner in two liberal welfare regimes (the United States and Australia) and two social democratic regimes (Sweden and Norway). We use survey-based union and birth histories in Australia and the United States and data from national population registers in Norway and Sweden to estimate the likelihood of experiencing childbearing across partnerships at any point in the childbearing career. We find that births with new partners constitute a substantial proportion of all births in each country we study. Despite quite different arrangements for social welfare, the determinants of childbearing across partnerships are very similar. Women who had their first birth at a very young age or who are less well educated are most likely to have children with different partners. Socioeconomic differentials in childbearing across partnerships appeared to be stronger in the United States, but not in comparison to differentials in childbearing in the same union. Thus, no strong evidence was found for a steeper educational gradient in the liberal as opposed to social democratic welfare regimes. The risk of childbearing across partnerships increased dramatically in all countries from the 1980s to the 2000s, and the educational differential also increased; again, however, the increases were not associated with welfare regime. PMID:24399143

Asystole and increased serum myoglobin levels associated with 'packing blackout' in a competitive breath-hold diver.

PubMed

Andersson, Johan P A; Linér, Mats H; Jönsson, Henrik

2009-11-01

Many competitive breath-hold divers use 'glossopharyngeal insufflation', also called 'lung packing', to overfill their lungs above normal total lung capacity. This increases intrathoracic pressure, decreases venous return, compromises cardiac pumping, and reduces arterial blood pressure, possibly resulting in a syncope breath-hold divers call 'packing blackout'. We report a case with a breath-hold diver who inadvertently experienced a packing blackout. During the incident, an electrocardiogram (ECG) and blood pressure were recorded, and blood samples for determinations of biomarkers of cardiac muscle perturbation (creatine kinase-MB isoenzyme (CK-MB), cardiac troponin-T (TnT), and myoglobin) were collected. The ECG revealed short periods of asystole during the period of 'packing blackout', simultaneous with pronounced reductions in systolic, diastolic, and pulse pressures. Serum myoglobin concentration was elevated 40 and 150 min after the incident, whereas there were no changes in CK-MB or TnT. The ultimate cause of syncope in this diver probably was a decrease in cerebral perfusion following glossopharyngeal insufflation. The asystolic periods recorded in this diver could possibly indicate that susceptible individuals may be put at risk of a serious cardiac incident if the lungs are excessively overinflated by glossopharyngeal insufflation. This concern is further substantiated by the observed increase in serum myoglobin concentration after the event.

Divergent hydrological response to large-scale afforestation and vegetation greening in China

PubMed Central

Ciais, Philippe; Huang, Ling; Wang, Kai; Zhou, Liming

2018-01-01

China has experienced substantial changes in vegetation cover, with a 10% increase in the leaf area index and an ~41.5 million-hectare increase in forest area since the 1980s. Earlier studies have suggested that increases in leaf area and tree cover have led to a decline in soil moisture and runoff due to increased evapotranspiration (ET), especially in dry regions of China. However, those studies often ignored precipitation responses to vegetation increases, which could offset some of the negative impact on soil moisture by increased ET. We investigated 30-year vegetation impacts on regional hydrology by allowing for vegetation-induced changes in precipitation using a coupled land-atmosphere global climate model, with a higher spatial resolution zoomed grid over China. We found high spatial heterogeneity in the vegetation impacts on key hydrological variables across China. In North and Southeast China, the increased precipitation from vegetation greening and the increased forest area, although statistically insignificant, supplied enough water to cancel out enhanced ET, resulting in weak impact on soil moisture. In Southwest China, however, the increase in vegetation cover significantly reduced soil moisture while precipitation was suppressed by the weakened summer monsoon. In Northeast China, the only area where forest cover declined, soil moisture was significantly reduced, by −8.1 mm decade−1, likely because of an intensified anticyclonic circulation anomaly during summer. These results suggest that offline model simulations can overestimate the increase of soil dryness in response to afforestation in North China, if vegetation feedbacks lead to increased precipitation like in our study. PMID:29750196

The Experience of Sexual Stigma and the Increased Risk of Attempted Suicide in Young Brazilian People from Low Socioeconomic Group

PubMed Central

Brandelli Costa, Angelo; Pasley, Andrew; Machado, Wagner de Lara; Alvarado, Ernesto; Dutra-Thomé, Luciana; Koller, Silvia Helena

2017-01-01

This study was intended to analyze the intersection of experience of sexual stigma low-socioeconomic status, and suicide attempt amongst young Brazilians (11–24 years old). In each of the data collection periods (2004–2006: n = 7185; 2010–2012: n = 2734), participants completed a questionnaire-based instrument. Network analysis provided support for a Minority Stress Model, oriented around whether participants had experienced sexual stigma. Although suicide attempts decreased by 20% for participants who had not experienced sexual stigma, there was a 60% increase for those who had experienced sexual stigma. Of particular note were the increases in rates of reported community and familial physical assault, molestation, and rape for those who had experienced sexual stigma. An analysis of centrality statistics demonstrated that both experiences of this Minority Stress Model were fundamentally different, and that those disparities increased over the time frame observed in this study. At the center of this model, shortest paths statistics exhibited a direct conditioned connection between experiencing sexual stigma and suicide attempts. We discuss the social and historical contexts that contributed to these dynamics, and emphasize the need for policy change. PMID:28275356

Residential patterns in older homeless adults: Results of a cluster analysis.

PubMed

Lee, Christopher Thomas; Guzman, David; Ponath, Claudia; Tieu, Lina; Riley, Elise; Kushel, Margot

2016-03-01

Adults aged 50 and older make up half of individuals experiencing homelessness and have high rates of morbidity and mortality. They may have different life trajectories and reside in different environments than do younger homeless adults. Although the environmental risks associated with homelessness are substantial, the environments in which older homeless individuals live have not been well characterized. We classified living environments and identified associated factors in a sample of older homeless adults. From July 2013 to June 2014, we recruited a community-based sample of 350 homeless men and women aged fifty and older in Oakland, California. We administered structured interviews including assessments of health, history of homelessness, social support, and life course. Participants used a recall procedure to describe where they stayed in the prior six months. We performed cluster analysis to classify residential venues and used multinomial logistic regression to identify individual factors prior to the onset of homelessness as well as the duration of unstable housing associated with living in them. We generated four residential groups describing those who were unsheltered (n = 162), cohabited unstably with friends and family (n = 57), resided in multiple institutional settings (shelters, jails, transitional housing) (n = 88), or lived primarily in rental housing (recently homeless) (n = 43). Compared to those who were unsheltered, having social support when last stably housed was significantly associated with cohabiting and institution use. Cohabiters and renters were significantly more likely to be women and have experienced a shorter duration of homelessness. Cohabiters were significantly more likely than unsheltered participants to have experienced abuse prior to losing stable housing. Pre-homeless social support appears to protect against street homelessness while low levels of social support may increase the risk for becoming homeless immediately after losing rental housing. Our findings may enable targeted interventions for those with different manifestations of homelessness. Published by Elsevier Ltd.

The Sagittarius dwarf galaxy: Where did all the gas go?

NASA Astrophysics Data System (ADS)

Tepper-García, Thor; Bland-Hawthorn, Joss

2018-05-01

The remarkable 1994 discovery of the Sagittarius dwarf galaxy (Sgr) revealed that, together with the Magellanic Clouds, there are at least three major dwarf galaxies, each with a total mass of order 1010 - 1011M⊙, falling onto the Galaxy in the present epoch. Beyond a Galactic radius of 300 kpc, dwarfs tend to retain their gas. At roughly 50 kpc, the Magellanic Clouds have experienced substantial gas stripping as evidenced by the Magellanic Stream which extends from them. Since Sgr experienced star formation long after it fell into the Galaxy, it is interesting to explore just how and when this dwarf lost its gas. To date, there has been no definitive detection of an associated gas component. We revisit recent simulations of the stellar and dark matter components of Sgr but, for the first time, include gas that is initially bound to the infalling galaxy. We find that the gas stripping was 30 - 50% complete at its first disc crossing ˜2.7 Gyr ago, then entirely stripped at its last disc crossing ˜1 Gyr ago. Our timeline is consistent with the last substantial burst of star formation in Sgr which occurred about the time of the last disc crossing. We discuss the consequences of gas stripping and conclude that the vast majority of the stripped gas was fully settled onto the Galaxy by ˜300 Myr ago. It is highly unlikely that any of the high- or intermediate-velocity clouds have a direct association with the Sgr dwarf.

A longitudinal investigation of depressive symptoms in undergraduate students of pharmacy in Syria.

PubMed

Gonçalves, Vânia; Zidan, Amani; Issa, Mona; Barah, Faraj

2012-05-01

This prospective longitudinal study investigated depressive symptoms and its association with students' demographic, academic, and health factors in undergraduate students of pharmacy in Syria. Students attending any year (1st to 5th year) were assessed in the first semester (time 1) and in the second semester (time 2). An academic year comprises two semesters of 16 weeks each. Data for 450 students were analyzed at time 1, and 262 students were assessed at the two time points. Our results showed that most of the students experienced depressive symptoms, with a substantial percentage presenting moderate to severe levels of symptoms (35% or 450 students at time 1; 23% or 262 students at time 2). Across the two semesters, a significant decrease in depressive symptoms was observed for students with complete data at the two time points. Depressive symptoms at time 2 increased significantly with increasing depressive scores at time 1 and decreasing students' expectations about their academic performance. Our results support the clear need for dynamic, full-time, and accessible psychological services at the university to promote and assess mental health and to deliver psychological interventions to students at need.

Effects of Simulated Rare Earth Recycling Wastewaters on Biological Nitrification.

PubMed

Fujita, Yoshiko; Barnes, Joni; Eslamimanesh, Ali; Lencka, Malgorzata M; Anderko, Andrzej; Riman, Richard E; Navrotsky, Alexandra

2015-08-18

Increasing rare earth element (REE) supplies by recycling and expanded ore processing will result in generation of new wastewaters. In some cases, disposal to a sewage treatment plant may be favored, but plant performance must be maintained. To assess the potential effects of such wastewaters on biological treatment, model nitrifying organisms Nitrosomonas europaea and Nitrobacter winogradskyi were exposed to simulated wastewaters containing varying levels of yttrium or europium (10, 50, and 100 ppm), and the extractant tributyl phosphate (TBP, at 0.1 g/L). Y and Eu additions at 50 and 100 ppm inhibited N. europaea, even when virtually all of the REE was insoluble. Provision of TBP with Eu increased N. europaea inhibition, although TBP alone did not substantially alter activity. For N. winogradskyi cultures, Eu or Y additions at all tested levels induced significant inhibition, and nitrification shut down completely with TBP addition. REE solubility was calculated using the previously developed MSE (Mixed-Solvent Electrolyte) thermodynamic model. The model calculations reveal a strong pH dependence of solubility, typically controlled by the precipitation of REE hydroxides but also likely affected by the formation of unknown phosphate phases, which determined aqueous concentrations experienced by the microorganisms.

Diagnosis and Management of Vertebral Compression Fractures.

PubMed

McCarthy, Jason; Davis, Amy

2016-07-01

Vertebral compression fractures (VCFs) are the most common complication of osteoporosis, affecting more than 700,000 Americans annually. Fracture risk increases with age, with four in 10 white women older than 50 years experiencing a hip, spine, or vertebral fracture in their lifetime. VCFs can lead to chronic pain, disfigurement, height loss, impaired activities of daily living, increased risk of pressure sores, pneumonia, and psychological distress. Patients with an acute VCF may report abrupt onset of back pain with position changes, coughing, sneezing, or lifting. Physical examination findings are often normal, but can demonstrate kyphosis and midline spine tenderness. More than two-thirds of patients are asymptomatic and diagnosed incidentally on plain radiography. Acute VCFs may be treated with analgesics such as acetaminophen, nonsteroidal anti-inflammatory drugs, narcotics, and calcitonin. Physicians must be mindful of medication adverse effects in older patients. Other conservative therapeutic options include limited bed rest, bracing, physical therapy, nerve root blocks, and epidural injections. Percutaneous vertebral augmentation, including vertebroplasty and kyphoplasty, is controversial, but can be considered in patients with inadequate pain relief with nonsurgical care or when persistent pain substantially affects quality of life. Family physicians can help prevent vertebral fractures through management of risk factors and the treatment of osteoporosis.

Prevalence and associated factors of domestic violence among pregnant women attending routine antenatal care in Nepal.

PubMed

Rishal, Poonam; Pun, Kunta Devi; Darj, Elisabeth; Joshi, Sunil Kumar; Bjørngaard, Johan Håkon; Swahnberg, Katarina; Schei, Berit; Lukasse, Mirjam

2017-08-01

The primary aim of this study was to assess the prevalence of domestic violence (DV) and its associated factors among pregnant women in Nepal. The secondary aims were to investigate disclosure of DV by women to health-care personnel and to assess whether health-care personnel had asked women about their experience of DV. This cross-sectional study included 2004 pregnant women between 12 and 28 weeks of gestation attending routine antenatal care at two hospitals in Nepal from August 2014 to November 2015. In this study, DV was defined as fear of a family member and/or an experience of physical, emotional or sexual violence. Associated risk factors were analysed using logistic regression analyses. Twenty-one per cent of the women had experienced DV; 12.5% experienced fear only, 3.6% violence only and 4.9% experienced both violence and fear. Less than 2% per cent reported physical violence during pregnancy. This study found that just 17.7% had ever been asked by health-care personnel about DV, and of the women who had reported DV, only 9.5% had disclosed their experience to health-care personnel. Women of young age and low socio-economic status were more likely to have experienced DV. Women who reported having their own income and the autonomy to use it were at significantly lower risk of DV compared to women with no income. A substantial proportion of women reported having experienced DV. Victims had rarely disclosed their experience of DV to health-care personnel. This study underlines the importance of integrating systematic assessment of DV in antenatal care.

Browning of Adirondack, NY Lakes: Rates and Effects

NASA Astrophysics Data System (ADS)

Driscoll, C. T.; Mota, Y.; Fakhraei, H.; Todorova, S.; Leach, T.; Rose, K. C.; O'Donnell, S.

2017-12-01

Browning, or increases in the concentrations of dissolved organic matter (DOM), is an intriguing recent phenomenon occurring in northern freshwaters. It is hypothesized that browning is a watershed response to decreases in acid deposition, although changing in climate may also contribute. The Adirondack region of NY is experiencing marked increases in lake concentrations of dissolved organic carbon (DOC), with 29 out of 48 lakes in the Adirondack Long-Term Monitoring (ALTM) program showing significant increases and two exhibiting decreases since 1992. Increases in DOC is altering the acid base status of Adirondack lakes largely due increases in DOM with strongly acidic functional groups. DOM mobilization limits increases in acid neutralizing capacity that can be achieved in recovery of surface waters from acid deposition. A subset of ALTM lakes also appear to be experiencing changes in their physical characteristics during the summer stratification period, consistent with increases in DOM and browning. Of 28 lakes monitored for water column profiles since 1994: 8 are showing declines in thermocline depth (5 significant, p<0.05); all are exhibiting increases in epilimnetic temperature (9 significant); 26 are experiencing increases in the difference between epilimnetic and hypolimnetic temperatures (6 significant); and 17 are experiencing decreases in hypolimnetic dissolved oxygen concentrations (6 significant decreases, 1 increase). These changes may be a manifestation of increases in the attenuation of light associated with increases in DOM, increasing the intensity and duration of thermal stratification.

Contraceptive use in a changing service environment: evidence from Indonesia during the economic crisis.

PubMed

Frankenberg, Elizabeth; Sikoki, Bondan; Suriastini, Wayan

2003-06-01

In the late 1990s, most Southeast Asian countries experienced substantial economic downturns that reduced social-sector spending and decreased individuals' spending power. Data from Indonesia were collected in 1997 (just before the crisis) and in 1998 (during the crisis) that are used in this study to examine changes in the contraceptive supply environment and in women's choices regarding contraceptive use. Despite substantial changes in providers' characteristics during the first year of the crisis, no statistically significant differences are found between 1997 and 1998 in overall levels of prevalence, in unmet need, or in method mix. Women's choices regarding source of contraceptive supplies, however, changed considerably over the period. Changes in the contraceptive supply environment are linked here to changes in women's choice of source of supply, and a number of providers' characteristics are found to be significantly associated with women's choices in this regard.

Prospective study of exogenous hormone use and breast cancer in Seventh-day Adventists.

PubMed

Mills, P K; Beeson, W L; Phillips, R L; Fraser, G E

1989-08-01

Exogenous hormone use as either oral contraceptives (OC) or hormone replacement therapy (HRT) was evaluated in reference to subsequent breast cancer risk in a cohort study of 20,341 Seventh-day Adventist women, residing in California, who completed a detailed lifestyle questionnaire in 1976 and who were followed for 6 years. During the follow-up period, 215 histologically confirmed primary breast cancers were detected in the cohort. The mean age at diagnosis was 66 years, indicating a primarily postmenopausal case series. In this cohort, after taking into account potentially confounding variables, current use of HRT (in 1976) was associated with a 69% increase in breast cancer risk, which was statistically significant (RR = 1.69; CI = 1.12-2.55). However, there was no strong increase in risk with increasing duration of use of HRT. Subgroups of women who did experience HRT associated increases in breast cancer risk included those women who had ever used HRT (RR = 1.39; CI = 1.00-1.94) and those with no history of maternal breast cancer (RR = 1.45), those women with prior benign breast disease (RR = 2.80), and those women who experienced menopause at 44 years of age or later (RR = 1.56). There was no substantial increase in breast cancer risk associated with use of OC in this population, although among women with exposure to both OC and HRT there was a suggested increase in risk (RR = 1.42; CI = 0.71-2.85).

Number of sexual partners and sexual assertiveness predict sexual victimization: do more partners equal more risk?

PubMed

Walker, Dave P; Messman-Moore, Terri L; Ward, Rose Marie

2011-01-01

In previous studies, number of sexual partners and sexual assertiveness were examined as independent risk factors for sexual victimization among college women. Using a sample of 335 college women, this study examined the interaction of number of sexual partners and sexual assertiveness on verbal sexual coercion and rape. Approximately 32% of the sample reported unwanted sexual intercourse, 6.9% (n = 23) experienced verbal sexual coercion, 17.9% (n = 60) experienced rape, and 7.2% (n = 24) experienced both. As number of sexual partners increased, instances of verbal sexual coercion increased for women low in relational sexual assertiveness but not for women high in relational sexual assertiveness. A similar relationship was not found for rape. Among women who experienced both verbal sexual coercion and rape, increases in number of partners in the context of low refusal and relational assertiveness were associated with increases in verbal sexual coercion and rape. Findings suggest sexual assertiveness is related to fewer experiences of sexual coercion.

Canadian community pharmacists' use of digital health technologies in practice.

PubMed

Leung, Valerie; Tharmalingam, Sukirtha; Cooper, Janet; Charlebois, Maureen

2016-01-01

In 2010, a pan-Canadian study on the current state and benefits of provincial drug information systems (DIS) found that substantial benefits were being realized and that pharmacists perceived DIS to be a valuable tool in the evolving models of pharmacy practice. To understand changes in digital health and the impact on practice since that time, a survey of community pharmacists in Canada was conducted. In 2014, Canada Health Infoway (Infoway) and the Canadian Pharmacists Association (CPhA) invited community pharmacists to participate in a Web-based survey to understand their use and perceived benefits of digital health in practice. The survey was open from April 15 to May 12, 2014. Of the 447 survey responses, almost all used some form of digital health in practice. Those with access to DIS and provincial laboratory information systems (LIS) reported increased productivity and better quality of care. Those without access to these systems would overwhelmingly like access. There have been significant advances in digital health and community pharmacy practice over the past several years. In addition to digital health benefits in the areas of productivity and quality of care, pharmacists are also experiencing substantial benefits in areas related to recently expanded scope of practice activities such as ordering lab tests. Community pharmacists frequently use digital health in practice and recognize the benefits of these technologies. Digital health is, and will continue to be, a key enabler for practice transformation and improved quality of care. Can Pharm J (Ott) 2016;149:xx-xx.

The end of measles and congenital rubella: an achievable dream?

PubMed

Adamo, G; Sturabotti, G; D'Andrea, E; Baccolini, V; Romano, F; Iannazzo, S; Marzuillo, C; Villari, P

2017-01-01

Despite substantial progress towards measles and rubella control, outbreaks continue to threaten elimination goals worldwide. This paper aims to document progress towards the global eradication of measles and rubella. In particular, it investigates the major challenges faced by Italy in reaching the elimination goals. A review of the most important literature was carried out. Furthermore, a systematic review of the scientific literature on measles and rubella in the Italian setting was performed for the period 2000-2016. In the National Plan 2010-2015, Italy renewed its commitment to eliminate measles and rubella by 2015. However, Italy recently experienced a high measles burden (2,205 cases in 2013, 1,694 in 2014). Between June 2015 and May 2016, 515 cases were reported, accounting for 28% all cases in Europe. Immunization coverage decreased in recent years, with no Region reaching the 95% target. The systematic review included a total of 175 papers, with an upward trend in the number of published articles, which demonstrates an increasing interest in the field of measles and rubella. The review highlights the need to improve the commitment of the Italian Regions to the elimination goals; to promote Supplementary Immunization Activities (SIAs); to improve the communication skills of health care workers; to improve the health literacy of citizens; and to enhance integrated measles and rubella surveillance. Elimination of measles and rubella in Italy will require a substantial improvement in both commitment of the 21 Regions and activity of the whole country towards the WHO goals.

How Feasible is Multiple Time Point Web-Based Data Collection with Individuals Experiencing Street Homelessness?

PubMed

Eyrich-Garg, Karin M; Moss, Shadiya L

2017-02-01

Three barriers investigators often encounter when conducting longitudinal work with homeless or other marginalized populations are difficulty tracking participants, high rates of no-shows for follow-up interviews, and high rates of loss to follow-up. Recent research has shown that homeless populations have substantial access to information technologies, including mobile devices and computers. These technologies have the potential both to make longitudinal data collection with homeless populations easier and to minimize some of these methodological challenges. This pilot study's purpose was to test whether individuals who were homeless and sleeping on the streets-the "street homeless"-would answer questions remotely through a web-based data collection system at regular "follow-up" intervals. We attempted to simulate longitudinal data collection in a condensed time period. Participants (N = 21) completed an in-person baseline interview. Each participant was given a remotely reloadable gift card. Subsequently, weekly for 8 weeks, participants were sent an email with a link to a SurveyMonkey questionnaire. Participants were given 48 h to complete each questionnaire. Data were collected about life on the streets, service use, community inclusion, substance use, and high-risk sexual behaviors. Ten dollars was remotely loaded onto each participant's gift card when they completed the questionnaire within the completion window. A substantial number of participants (67% of the total sample and 86% of the adjusted sample) completed at least seven out of the eight follow-up questionnaires. Most questionnaires were completed at public libraries, but several were completed at other types of locations (social service agencies, places of employment, relative/friend/acquaintance's domiciles, or via mobile phone). Although some of the questions were quite sensitive, very few participants skipped any questions. The only variables associated with questionnaire completion were frequency of computer use and education-both positive associations. This pilot study suggests that collecting longitudinal data online may be feasible with a subpopulation of persons experiencing homelessness. We suspect that participant follow-up rates using web-based data collection methods have the potential to exceed follow-up rates using traditional in-person interviews. If this population of persons experiencing street homelessness can be successful with this method of data collection, perhaps other disenfranchised, difficult-to-track, or difficult-to-reach populations could be followed using web-based data collection methods. Local governments are striving to decrease the "digital divide," providing free or greatly discounted wi-fi connectivity as well as mobile computer lab access to low-income geographic areas. These actions, in combination with increased smart phone ownership, may permit vulnerable populations to connect and communicate with investigators.

Young Children Experiencing Homelessness: The Overlooked Medium of Play

ERIC Educational Resources Information Center

Schlembach, Sue

2017-01-01

The number of mothers with young children experiencing homelessness and seeking shelter has increased in the USA over the past decade. Shelters are often characterized as environments offering few opportunities for appropriate play experiences. This article delineates the important role of play for young children experiencing homelessness and…

Daily reports of witnessing and experiencing peer harassment in middle school.

PubMed

Nishina, Adrienne; Juvonen, Jaana

2005-01-01

Two studies examined daily incidents of peer harassment in urban middle schools. Sixth-grade students (M age = 11 years) described their daily personal experiences and witnessed accounts of peer harassment, and rated their negative feelings across a 2-week period. In Study 1 (n = 95), within-subject analyses across 4 days revealed that both personally experienced and witnessed harassment were associated with increases in daily anxiety, whereas witnessing harassment buffered students against increases in humiliation on days when they personally experienced harassment. Evidence for witnessing as a buffer against increases in humiliation and anger was also found in Study 2 (n = 97) that included 5 daily reports. Witnessing harassment also protected students against increases in negative self-perceptions.

The Influence of Swirl Brakes and a Tip Discharge Orifice on the Rotordynamic Forces Generated by Discharge-to-Suction Leakage Flows in Shrouded Centrifugal Pumps

NASA Technical Reports Server (NTRS)

Sivo, Joseph M.; Acosta, A. J.; Brennen, C. E.; Caughey, T. K.

1993-01-01

Recent experiments conducted in the Rotor Force Test Facility at the California Institute of Technology have examined the effects of a tip leakage restriction and swirl brakes on the rotordynamic forces due to leakage flows on an impeller undergoing a prescribed circular whirl. The experiments simulate the leakage flow conditions and geometry of the Alternate Turbopump Design (ATD) of the Space Shuttle High Pressure Oxygen Turbopump and are critical to evaluating the pump's rotordynamic instability problems. Previous experimental and analytical results have shown that discharge-to-suction leakage flows in the annulus of a shrouded centrifugal pump contribute substantially to the fluid induced rotordynamic forces. Also, previous experiments have shown that leakage inlet (pump discharge) swirl can increase the cross-coupled stiffness coefficient and hence increase the range of positive whirl for which the tangential force is destabilizing. In recent experimental work, the present authors demonstrated that when the swirl velocity within the leakage path is reduced by the introduction of ribs or swirl brakes, then a substantial decrease in both the destabilizing normal and tangential forces could be achieved. Motivation for the present research is that previous experiments have shown that restrictions such as wear rings or orifices at pump inlets affect the leakage forces. Recent pump designs such as the Space Shuttle Alternate Turbopump Design (ATD) utilize tip orifices at discharge for the purpose of establishing axial thrust balance. The ATD has experienced rotordynamic instability problems and one may surmise that these tip discharge orifices may also have an important effect on the normal and tangential forces in the plane of impeller rotation. The present study determines if such tip leakage restrictions contribute to undesirable rotordynamic forces. Additional motivation for the present study is that the widening of the leakage path annular clearance and the installation of swirl brakes in the ATD has been proposed to solve its instability problems. The present study assesses the effect of such a design modification on the rotordynamic forces. The experimental apparatus consists of a solid or dummy impeller, a housing instrumented for pressure measurements, a rotating dynamometer and an eccentric whirl mechanism. The solid impeller is used so that leakage flow contributions to the forces are measured, but the main throughflow contributions are not experienced. The inner surface of the housing has been modified to accommodate meridional ribs or swirl brakes within the leakage annulus. In addition, the housing has been modified to accommodate a discharge orifice that qualitatively simulates one side of the balance piston orifice of the Space Shuttle ATD. Results indicate the detrimental effects of a discharge orifice and the beneficial effects of brakes. Plots of the tangential and normal forces versus whirl ratio show a substantial increase in these forces along with destabilizing resonances at some positive whirl ratios when a discharge orifice is added. When brakes are added, some of the detrimental effects of the orifice are reduced. For the tangential force, a plot versus whirl ratio shows a significant reduction and a destabilizing resonance appears to be eliminated. For the normal force, although the overall force is not reduced, again a destabilizing resonance appears to be eliminated.

Glacier lake outburst floods caused by glacier shrinkage: case study of Ala-Archa valley, Kyrgyz Ala Too, northern Tian Shan, Kyrgyzstan

NASA Astrophysics Data System (ADS)

Petrakov, D.; Erochin, S. A.; Harbor, J.; Ivanov, M.; Rogozhina, I.; Stroeven, A. P.; Usubaliev, R.

2012-12-01

Changes in glacier extent and runoff in Central Asia increase socio-economic stress and may result in political conflict between donors of freshwater (Kyrgyzstan, Tajikistan) and recipients of freshwater (Uzbekistan, China). Glaciers in the Pamir and Tian Shan regions have experienced an unprecedented downwasting due to regional climate changes over the past decades. This is because air temperature increases are in some areas accompanied by a decrease in precipitation. Such conditions have already resulted in a reduction of glacier runoff, especially in the northern and western Tian Shan, and an increase of the number and area of glacial lakes in Kyrgyzstan. Even though glacial lakes in the mountains are in general relatively small and located far from densely populated areas, their outbursts often produce destructive debris flows. Such debris flows are especially common in Kyrgyzstan because of its steep river channels and abundance of Holocene and Quaternary glacier deposits that can be remobilized. The glacial lake outburst flood (GLOF) in the Shakhimardan river catchment in 1999, for example, resulted in 100 fatalities in Uzbekistan, and the GLOF from the Zyndan glacial lake led to substantial economic losses in 2009. According to the latest inventory, there are more than 350 glacial lakes in Kyrgyzstan of which about 70 occur in the Kyrgyz Ala Too. The Ala-Archa valley is among the most important glacierized catchments in Kyrgyzstan. Despite the presence of a relatively small glacier-covered area of 36 km2, the Ala-Archa river is of critical importance to the Bishkek area, its agriculture, and its population which currently exceeds one million. GLOFs are therefore a threat to both numerous settlements of touristic value in the Ala-Archa headwaters and to Bishkek. The Teztor lake in the Adygene catchment of the Ala-Archa river system experienced an outburst during 1988 and 2005. On the early morning of July 31, 2012, this lake began draining through a dam composed of stagnant ice and debris. With the water discharge being merely a few m3/s, the GLOF transformed into a debris flow beyond a steep front of rock glacier, which is within 150 m downstream of the lake. After rushing through the ca. 7 km-long Adygene valley, the debris flow formed a fan in the Ala-Archa valley and transformed into a flood. The flood wave reached Bishkek located more than 40 km downstream. This led to a panic amongst local dwellers and Bishkek residents. The maximum discharge of the debris flow in the lower part of the Adygene valley was assessed as 300 m3/s and the discharge of the flood in Bishkek as 35 m3/s. The latter exceeds the standard discharge of the Ala-Archa river substantially. Although no fatalities resulted from this event, economic losses as a consequence of a destroyed mineral water factory could possibly amount to USD 200000, which is a substantial sum by Kyrgyz standards. Because of the prior history, it is expected that GLOFs from the Teztor valley will recur in the upcoming years. We conclude that installation of an early warning system in lower Adygene valley is needed to prevent further damage in the study area.

Corrosion testing using isotopes

DOEpatents

Hohorst, F.A.

1995-12-05

A method is described for determining the corrosion behavior of a material with respect to a medium in contact with the material by: implanting a substantially chemically inert gas in a matrix so that corrosion experienced by the material causes the inert gas to enter the medium; placing the medium in contact with the material; and measuring the amount of inert gas which enters the medium. A test sample of a material whose resistance to corrosion by a medium is to be tested is described composed of: a body of the material, which body has a surface to be contacted by the medium; and a substantially chemically inert gas implanted into the body to a depth below the surface. A test sample of a material whose resistance to corrosion by a medium is to be tested is described composed of: a substrate of material which is easily corroded by the medium, the substrate having a surface; a substantially chemically inert gas implanted into the substrate; and a sheet of the material whose resistance to corrosion is to be tested, the sheet being disposed against the surface of the substrate and having a defined thickness. 3 figs.

Early maltreatment is associated with greater risk of conduct problems and lack of guilt in adolescence.

PubMed

Docherty, Meagan; Kubik, Joanna; Herrera, Carolina M; Boxer, Paul

2018-05-01

Previous research indicates a link between childhood maltreatment and elevated conduct problems. Yet the literature is less clear on associations between maltreatment and callousness (e.g., lack of empathy or guilt). This is a critical gap given that callousness is a robust predictor of serious aggressive and violent behavior. We examine the association between substantiated maltreatment events in childhood and adolescence (up to age 13) and conduct problems and lack of guilt at age 14. We analyze self- and parent-report data along with official maltreatment records on 557 youth (50% female; 69% non-white) from a larger dataset (Longitudinal Studies on Childhood Abuse and Neglect; N = 1354). Results of multinomial logistic regression models indicate that youth with histories of substantiated maltreatment events are more likely to have elevated conduct problems and decreased guilt at age 14, particularly if they experienced maltreatment before the age of four years old. Youth who exhibit conduct problems and also appear to lack guilt are more likely to have a personal history of substantiated maltreatment. We discuss our results in terms of their implications for theory and practice. Copyright © 2018 Elsevier Ltd. All rights reserved.

Environment: Language Ecology and Language Death

NASA Astrophysics Data System (ADS)

Romaine, Suzanne

Global linguistic diversity is rapidly declining. As the world becomes less linguistically diverse, it is becoming culturally less diverse as well as the world's tribes and languages are dying out or being assimilated into modern civilization because their habitats are being destroyed. At the same time the world is experiencing a substantial decline in biodiversity. The extinction of languages is part of the larger picture of near total collapse of the worldwide ecosystem, and languages are vital parts of complex local ecologies that must be supported if global biodiversity is to be maintained.

Establishing and maintaining a satellite campus connected by synchronous video conferencing.

PubMed

Fox, Brent I; McDonough, Sharon L; McConatha, Barry J; Marlowe, Karen F

2011-06-10

Pharmacy education has experienced substantial growth in the number of new schools and existing schools establishing satellite campuses. Several models have previously been used to connect primary and satellite campuses. We describe the Auburn University Harrison School of Pharmacy's (AUHSOP's) experiences using synchronous video conferencing between the Auburn University campus in Auburn and a satellite campus in Mobile, Alabama. We focus on the technology considerations related to planning, construction, implementation, and continued use of the various resources that support our program. Students' perceptions of their experiences related to technology also are described.

[Links and effects of globalization on social and economic organization and malaria prevalence in the Coastal Region of Livingston, Guatemala].

PubMed

Nelson, Caro Méndez

2007-01-01

As a result of Guatemala's growing involvement in international markets and policies favoring industrial and export-oriented efforts, the population has experienced substantial changes in its economic and social organization, with consequences for the health and well-being of marginal groups. The article discusses various links between global processes, national policies and priorities, social and economic strategies, and malaria prevalence, with the Coastal Region of Livingston, Guatemala as the case study carried out between 2001 and 2003.

Children and divorce: overview and analysis.

PubMed

Behrman, R E

1994-01-01

Over the past two decades, more than one million children each year have experienced a family divorce, and the proportion of children affected by divorce is expected to grow substantially in the twenty-first century. Most of these children experience significant changes in their living arrangements, and the poverty rate for children of divorce is about twice the rate for all children in the United States. We are, therefore, devoting this issue of the journal to divorce because it is a crucial factor in the lives of millions of children in this country.

Adolescent Sexual Debut and Later Delinquency

ERIC Educational Resources Information Center

Armour, Stacy; Haynie, Dana L.

2007-01-01

Does sexual debut (i.e., experiencing sexual intercourse for the first time) increase the risks of participating in later delinquent behavior? Does this risk increase if adolescents experience early sexual debut relative to the timing experienced by one's peers? Although many factors have been linked to sexual debut, little research has examined…

Laser-induced reaction alumina coating on ceramic composite

NASA Astrophysics Data System (ADS)

Xiao, Chenghe

Silicon carbide ceramics are susceptible to corrosion by certain industrial furnace environments. It is also true for a new class of silicon carbide-particulate reinforced alumina-matrix composite (SiCsb(P)Alsb2Osb3) since it contains more than 55% of SiC particulate within the composite. This behavior would limit the use of SiCsb(P)Alsb2Osb3 composites in ceramic heat exchangers. Because oxide ceramics corrode substantially less in the same environments, a laser-induced reaction alumina coating technique has been developed for improving corrosion resistance of the SiCsb(P)Alsb2Osb3 composite. Specimens with and without the laser-induced reaction alumina coating were subjected to corrosion testing at 1200sp°C in an air atmosphere containing Nasb2COsb3 for 50 ˜ 200 hours. Corroded specimens were characterized via x-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive spectrometer (EDS). The uncoated SiCsbP/Alsb2Osb3 composite samples experienced an initial increase in weight during the exposure to Nasb2COsb3 at 1200sp°C due to the oxidation of residual aluminum metal in the composite. There was no significant weight change difference experienced during exposure times between 50 and 200 hours. The oxidation layer formed on the as-received composite surface consisted of Si and Alsb2Osb3 (after washing with a HF solution). The oxidation layer grew outward and inward from the original surface of the composite. The growth rate in the outward direction was faster than in the inward direction. The formation of the Si/Alsb2Osb3 oxidation layer on the as-received composite was nonuniform, and localized corrosion was observed. The coated samples experienced very little mass increase. The laser-induced reaction alumina coating effectively provided protection for the SiCsbP/Alsb2Osb3 composite by keeping the corrodents from contacting the composite and by the formation of some refractory compounds such as Nasb2OAlsb2Osb3SiOsb2 and Nasb2Alsb{22}Osb{34}. After exposure to 1200sp°C for 200 hours, the bonding between the laser-induced reaction alumina coating and the composite appeared to be unattacked. For both the coated and uncoated samples, porosity within the composite increased after exposure due to the reaction: 3SiOsb2(s) + 4Al(l) -> 2Alsb2Osb3(s) + Si(s).

Health professionals responding to men for safety (HERMES): feasibility of a general practice training intervention to improve the response to male patients who have experienced or perpetrated domestic violence and abuse.

PubMed

Williamson, Emma; Jones, Sue K; Ferrari, Giulia; Debbonaire, Thangam; Feder, Gene; Hester, Marianne

2015-05-01

To evaluate a training intervention for general practice-based doctors and nurses in terms of the identification, documentation, and referral of male patients experiencing or perpetrating domestic violence and abuse (DVA) in four general practices in the south west of England. Research suggests that male victims and perpetrators of DVA present to primary care clinicians to seek support for their experiences. We know that the response of primary care clinicians to women patients experiencing DVA improves from training and the establishment of referral pathways to specialist DVA services. The intervention consisted of a 2-h practice-based training. Outcome measures included: a pre-post, self-reported survey of staff practice; disclosures of DVA as documented in medical records pre-post (six months) intervention; semi-structured interviews with clinicians; and practice-level contact data collected by DVA specialist agencies. Results show a significant increase in clinicians' self-reported preparedness to meet the needs of male patients experiencing or perpetrating DVA. There was a small increase in male patients identified within the medical records (6 pre- to 17 post-intervention) but only five of those patients made contact with a specialist DVA agency identified within the referral pathway. The training increased clinicians' confidence in responding to male patients affected by DVA. The increase in recorded identification of DVA male patients experiencing or perpetrating DVA was small and contact of those patients with a specialist DVA support service was negligible. We need to better understand male help seeking in relation to DVA, further develop interventions to increase identification of male patients experiencing or perpetrating DVA behaviours, and facilitate access to support services.

The Online Life of Individuals Experiencing Socioeconomic Disadvantage: How Do They Experience Information?

ERIC Educational Resources Information Center

Smeaton, Kathleen; Bruce, Christine S.; Hughes, Hilary; Davis, Kate

2017-01-01

Introduction: This paper explores the online information experiences of individuals experiencing socioeconomic disadvantage in Australia. As access to online information becomes increasingly critical those without access are in danger of being left behind. This exploratory pilot study examines the way that digital exclusion may be experienced.…

Learning from Families Experiencing Homelessness--How School Leaders Can Make a Difference through Transformative Leadership

ERIC Educational Resources Information Center

Warke, Amy L.

2012-01-01

Homelessness is a growing phenomenon, especially among women and children (Hulchanski, 2009). This study was conducted because of the increase in families experiencing homelessness registering in my school. In none of the current studies about homelessness have the researchers spoken to the families and children experiencing homelessness. This…

Martial arts fall techniques reduce hip impact forces in naive subjects after a brief period of training.

PubMed

Weerdesteyn, V; Groen, B E; van Swigchem, R; Duysens, J

2008-04-01

Hip fractures are among the most serious consequences of falls in the elderly. Martial arts (MA) fall techniques may reduce hip fracture risk, as they are known to reduce hip impact forces by approximately 30% in experienced fallers. The purpose of this study was to investigate whether hip impact forces and velocities in MA falls would be smaller than in a 'natural' fall arrest strategy (Block) in young adults (without any prior experience) after a 30-min training session in sideways MA fall techniques. Ten subjects fell sideways from kneeling height. In order to identify experience-related differences, additional EMG data of both fall types were collected in inexperienced (n=10) and experienced fallers (n=5). Compared to Block falls, MA falls had significantly smaller hip impact forces (-17%) and velocities (-7%). EMG results revealed experience-related differences in the execution of the MA fall, indicative of less pronounced trunk rotation in the inexperienced fallers. This may explain their smaller reduction of impact forces compared to experienced fallers. In conclusion, the finding that a substantial reduction in impact forces can be achieved after a short training in MA techniques is very promising with respect to their use in interventions to prevent fall injuries.

Ticagrelor for Neuroendovascular Procedures: A Case Series.

PubMed

Davis, Kyle; Morrison, Christopher

2018-02-01

The development of thromboembolism is one of the most common complications of neuroendovascular procedures. Although several small studies have deemed clopidogrel safe and effective in the prevention of intracranial stent thrombosis, ticagrelor has yet to be assessed in this setting. The objective of this study was to retrospectively evaluate the safety and efficacy of ticagrelor in patients undergoing neuroendovascular procedures. A retrospective review of patients receiving ticagrelor following neuroendovascular aneurysm repair. A total of 5 patients undergoing neuroendovascular aneurysm repair received ticagrelor for a median of 5 days while hospitalized. Three patients were treated with stent-assisted coiling, while 2 received pipeline embolization devices. All patients received additional low-dose aspirin therapy. One patient received ticagrelor after experiencing a thrombotic event on clopidogrel, while a second patient was treated with ticagrelor after developing a dermatologic reaction to clopidogrel. Three (60%) patients were successfully treated and discharged on ticagrelor therapy. Two patients experienced cerebrovascular accidents following aneurysm repair while receiving ticagrelor, one of which was potentially due to medication omission. One (20%) patient receiving ticagrelor experienced a small retroperitoneal hematoma; however, ticagrelor therapy was continued without further complication. Therapy with ticagrelor may be a safe and effective treatment option for patients undergoing neuroendovascular aneurysm repair. However, future studies are warranted to substantiate these findings.

The rise of digital direct-to-consumer advertising?: Comparison of direct-to-consumer advertising expenditure trends from publicly available data sources and global policy implications.

PubMed

Mackey, Tim K; Cuomo, Raphael E; Liang, Bryan A

2015-06-19

Pharmaceutical marketing is undergoing a major shift in the United States, in part due to new transparency regulations under the healthcare reform act. Changes in pharmaceutical marketing practices include a possible shift from more traditional forms of direct-to-consumer advertising towards emerging use of Internet-based DTCA ("eDTCA") given the growing importance of digital health or "eHealth." Though legally allowed only in the U.S. and New Zealand, eDTCA poses novel regulatory challenges, as it can cross geopolitical boundaries and impact health systems and populations outside of these countries. We wished to assess whether changes in DTCA and eDTCA expenditure trends was occurring using publicly available pharmaceutical marketing data. DTCA data was analyzed to compare trends in aggregate marketing expenditures and to assess if there were statistically significant differences in trends and magnitudes for data sources and DTCA sub-categories (including eDTCA). This was accomplished using regression lines of DTCA trend data and conducting pairwise comparisons of regression coefficients using t-tests. Means testing was utilized for comparing magnitude of DTCA expenditure. Data from multiple data sources indicate that aggregate DTCA expenditures have slightly declined during the period from 2005-2009 and are consistent with results from other studies. For DTCA sub-categories, television remained the most utilized form of DTCA, though experienced trends of declining expenditures (-13.2 %) similar to other traditional media platforms such as radio (-30.7 %) and outdoor ads (-12.1 %). The only DTCA sub-category that experienced substantial increased expenditures was eDTCA (+109.0 %) and it was the only medium that had statistically significant differences in its marketing expenditure trends compared to other DTCA sub-categories. Our study indicates that traditional DTCA marketing may be on the decline. Conversely, the only DTCA sub-category that experienced significant increases was eDTCA. However, to fully understand this possible shift to "digital" DTCA, improvements in publicly available DTCA data sources are necessary to confirm changing trends and validate existing data. Hence, utilizing the newly implemented U.S. physician-payment expenditure transparency requirements, we advocate for the mandatory disclosure of DTCA/eDTCA in order to inform future domestic and international health policy efforts regarding appropriate regulation of pharmaceutical promotion.

Gambling and Adverse Life Events Among Urban Adolescents

PubMed Central

Lee, Grace P.; Derevensky, Jeffrey L.; Ialongo, Nicholas S.; Martins, Silvia S.

2011-01-01

This study explored the cross sectional association between adverse life events and gambling in a sample of 515 urban adolescents (average age 17, 55% male, 88% African American). Approximately half of the sample had gambled in the past year (51%); 78% of the gamblers gambled monthly and 39% had a gambling-related problem. On the other hand, 88% of the sample had experienced at least one life event in the past year, and those experiencing events tended to live in more disadvantaged neighborhoods. The mere acknowledgement of experiencing a stressful life event in the past year (yes/no) was not associated with an increase in odds of being a gambler, with gambling more frequently, or with having a gambling problem. However, when the context of the event was considered, an association was found between directly experiencing threatening and deviant/violent types of events and frequent gambling (OR > 2). Additionally, the probability of being a gambler increased as the number of events experienced increased (aOR = 1.07, 95% CI = 1.01, 1.13, P = 0.013), but problems among gamblers were not associated with the number of events experienced (aOR = 1.01, 95% CI = 0.92, 1.11, P = 0.876). During adolescence, life events appear to be connected more with the frequency of gambling rather than with problems related to gambling. PMID:21614529

Brainstem cavernous malformations: Natural history versus surgical management.

PubMed

Walcott, Brian P; Choudhri, Omar; Lawton, Michael T

2016-10-01

While brainstem cavernous malformations were once considered inoperable, improvements in patient selection, surgical exposures, intraoperative MRI-guidance, MR tractography, and neurophysiologic monitoring have resulted in good outcomes in the majority of operated patients. In a consecutive series of 104 patients with brainstem cavernous malformations, only 14% of patients experienced cranial nerve or motor dysfunction that was worse at late follow-up, relative to their preoperative condition. Outcomes were predicted by several factors, including larger lesion size, lesions that crossed the midline, the presence of a developmental venous anomaly, older age, and greater time interval from lesion hemorrhage to surgery. The 14% of patients who experienced a persistent neurological deficit as a result of surgery, while substantial from any perspective, compares favorably with the risks of observation based on a recent meta-analysis. Curative resection is a safe and effective treatment for brainstem cavernous malformations that will prevent re-hemorrhage in symptomatic patients. Copyright © 2016 Elsevier Ltd. All rights reserved.

Unemployment among women: examining the relationship of physical and psychological intimate partner violence and posttraumatic stress disorder.

PubMed

Kimerling, Rachel; Alvarez, Jennifer; Pavao, Joanne; Mack, Katelyn P; Smith, Mark W; Baumrind, Nikki

2009-03-01

Prior research has demonstrated that intimate partner violence (IPV) is associated with employment instability among poor women. The current study assesses the broader relationship between IPV and women's workforce participation in a population-based sample of 6,698 California women. We examined past-year IPV by analyzing specific effects of physical violence, psychological violence, and posttraumatic stress disorder (PTSD) symptoms as predictors of unemployment. Results indicated substantial rates of unemployment among women who reported IPV, with rates of 20% among women who experienced psychological violence, 18% among women who experienced physical violence, and 19% among women with PTSD symptoms. When the relationship was adjusted for demographic characteristics and educational attainment, PTSD (adjusted odds ratio [AOR] = 1.60; 95% confidence interval [CI] = 1.22, 2.09) and psychological violence (AOR = 1.78; 95% CI = 1.36, 2.32), but not physical violence, were associated with unemployment. Implications for supported employment programs and workplace responses to IPV are discussed.

Effects of work stress on work-related rumination, restful sleep, and nocturnal heart rate variability experienced on workdays and weekends.

PubMed

Vahle-Hinz, Tim; Bamberg, Eva; Dettmers, Jan; Friedrich, Niklas; Keller, Monika

2014-04-01

The present study reports the lagged effects of work stress on work-related rumination, restful sleep, and nocturnal heart rate variability experienced during both workdays and weekends. Fifty employees participated in a diary study. Multilevel and regression analyses revealed a significant relationship between work stress measured at the end of a workday, work-related rumination measured during the evening, and restful sleep measured the following morning. Work stress, measured as the mean of 2 consecutive workdays, was substantially but not significantly related to restful sleep on weekends. Work stress was unrelated to nocturnal heart rate variability. Work-related rumination was related to restful sleep on weekends but not on workdays. Additionally, work-related rumination on weekends was positively related to nocturnal heart rate variability during the night between Saturday and Sunday. No mediation effects of work stress on restful sleep or nocturnal heart rate variability via work-related rumination were confirmed.

Racial and ethnic disparities in hospital care resulting from air pollution in excess of federal standards.

PubMed

Hackbarth, Andrew D; Romley, John A; Goldman, Dana P

2011-10-01

This study investigates racial and ethnic disparities in hospital admission and emergency room visit rates resulting from exposure to ozone and fine particulate matter levels in excess of federal standards ("excess attributable risk"). We generate zip code-level ambient pollution exposures and hospital event rates using state datasets, and use pollution impact estimates in the epidemiological literature to calculate excess attributable risk for racial/ethnic groups in California over 2005-2007. We find that black residents experienced roughly 2.5 times the excess attributable risk of white residents. Hispanic residents were exposed to the highest levels of pollution, but experienced similar excess attributable risk to whites. Asian/Pacific Islander residents had substantially lower excess attributable risk compared to white. We estimate the distinct contributions of exposure and other factors to these results, and find that factors other than exposure can be critical determinants of pollution-related disparities. Copyright © 2011 Elsevier Ltd. All rights reserved.

Exploring the Experience of Novelty When Viewing Creative Adverts: An ERP Study.

PubMed

Zhou, Shujin; Yin, Yue; Yu, Tingting; Stupple, Edward J N; Luo, Junlong

2018-01-01

The electrophysiological correlates of experiencing novelty in creative advertising were studied in 28 healthy subjects using event-related potentials. Participants viewed images that were difficult to interpret until a description was presented providing either a creative description (CD) featuring an unexpected description of the image based on the original advertisement, or a normal description (ND), which was a literal description of the image (and served as a baseline condition). Participants evaluated the level of creativity of the description. The results showed that the N2 amplitude was higher for CDs than for NDs across middle and right scalp regions between 240 and 270 ms, most likely reflecting conflict detection. Moreover, CDs demonstrated greater N400 than NDs in a time window between 380 and 500 ms, it is argued that this reflects semantic integration. The present study investigates the electrophysiological correlates of experiencing novelty in advertising with ecologically valid stimuli. This substantially extends the findings of earlier laboratory studies with more artificial stimuli.

Elimination sequence optimization for SPAR

NASA Technical Reports Server (NTRS)

Hogan, Harry A.

1986-01-01

SPAR is a large-scale computer program for finite element structural analysis. The program allows user specification of the order in which the joints of a structure are to be eliminated since this order can have significant influence over solution performance, in terms of both storage requirements and computer time. An efficient elimination sequence can improve performance by over 50% for some problems. Obtaining such sequences, however, requires the expertise of an experienced user and can take hours of tedious effort to affect. Thus, an automatic elimination sequence optimizer would enhance productivity by reducing the analysts' problem definition time and by lowering computer costs. Two possible methods for automating the elimination sequence specifications were examined. Several algorithms based on the graph theory representations of sparse matrices were studied with mixed results. Significant improvement in the program performance was achieved, but sequencing by an experienced user still yields substantially better results. The initial results provide encouraging evidence that the potential benefits of such an automatic sequencer would be well worth the effort.

Saturation of subjective reward magnitude as a function of current and pulse frequency.

PubMed

Simmons, J M; Gallistel, C R

1994-02-01

In rats with electrodes in the medial forebrain bundle, the upper portion of the function relating the experienced magnitude of the reward to pulse frequency was determined at currents ranging from 100 to 1,000 microA. The pulse frequency required to produce an asymptotic level of reward was inversely proportional to current except at the lowest currents and highest pulse frequencies. At a given current, the subjective reward magnitude functions decelerated to an asymptote over an interval in which the pulse frequency doubled or tripled. The asymptotic level of reward was approximately constant for currents between 200 and 1,000 microA but declined substantially at currents at or below 100 microA and pulse frequencies at or above 250 to 400 pulses per second. The results are consistent with the hypothesis that the magnitude of the experienced reward depends only on the number of action potentials generated by the train of pulses in the bundle of reward-relevant axons.

Strategies to Address English Language Writing Challenges Faced by International Graduate Students in the US

ERIC Educational Resources Information Center

Ravichandran, Swathi; Kretovics, Mark; Kirby, Kara; Ghosh, Ankita

2017-01-01

Since 2000, there has been a 72% increase in the number of international students attending US institutions of higher education. The increase, specifically of international graduate students, has brought to light the writing challenges experienced by this population of students. This study explored specific writing challenges experienced by…

Increasing Young Children's Contact with Print during Shared Reading: Longitudinal Effects on Literacy Achievement

ERIC Educational Resources Information Center

Piasta, Shayne B.; Justice, Laura M.; McGinty, Anita S.; Kaderavek, Joan N.

2012-01-01

Longitudinal results for a randomized-controlled trial (RCT) assessing the impact of increasing preschoolers' attention to print during reading are reported. Four-year-old children (N = 550) in 85 classrooms experienced a 30-week shared reading program implemented by their teachers. Children in experimental classrooms experienced shared-book…

Influencing organisational culture to improve hospital performance in care of patients with acute myocardial infarction: a mixed-methods intervention study

PubMed Central

Curry, Leslie A; Brault, Marie A; Linnander, Erika L; McNatt, Zahirah; Brewster, Amanda L; Cherlin, Emily; Flieger, Signe Peterson; Ting, Henry H; Bradley, Elizabeth H

2018-01-01

Background Hospital organisational culture affects patient outcomes including mortality rates for patients with acute myocardial infarction; however, little is known about whether and how culture can be positively influenced. Methods This is a 2-year, mixed-methods interventional study in 10 US hospitals to foster improvements in five domains of organisational culture: (1) learning environment, (2) senior management support, (3) psychological safety, (4) commitment to the organisation and (5) time for improvement. Outcomes were change in culture, uptake of five strategies associated with lower risk-standardised mortality rates (RSMR) and RSMR. Measures included a validated survey at baseline and at 12 and 24 months (n=223; average response rate 88%); in-depth interviews (n=393 interviews with 197 staff); and RSMR data from the Centers for Medicare and Medicaid Services. Results We observed significant changes (p<0.05) in culture between baseline and 24 months in the full sample, particularly in learning environment (p<0.001) and senior management support (p<0.001). Qualitative data indicated substantial shifts in these domains as well as psychological safety. Six of the 10 hospitals achieved substantial improvements in culture, and four made less progress. The use of evidence-based strategies also increased significantly (per hospital average of 2.4 strategies at baseline to 3.9 strategies at 24 months; p<0.05). The six hospitals that demonstrated substantial shifts in culture also experienced significantly greater reductions in RSMR than the four hospitals that did not shift culture (reduced RSMR by 1.07 percentage points vs 0.23 percentage points; p=0.03) between 2011–2014 and 2012–2015. Conclusions Investing in strategies to foster an organisational culture that supports high performance may help hospitals in their efforts to improve clinical outcomes. PMID:29101292

Influencing organisational culture to improve hospital performance in care of patients with acute myocardial infarction: a mixed-methods intervention study.

PubMed

Curry, Leslie A; Brault, Marie A; Linnander, Erika L; McNatt, Zahirah; Brewster, Amanda L; Cherlin, Emily; Flieger, Signe Peterson; Ting, Henry H; Bradley, Elizabeth H

2018-03-01

Hospital organisational culture affects patient outcomes including mortality rates for patients with acute myocardial infarction; however, little is known about whether and how culture can be positively influenced. This is a 2-year, mixed-methods interventional study in 10 US hospitals to foster improvements in five domains of organisational culture: (1) learning environment, (2) senior management support, (3) psychological safety, (4) commitment to the organisation and (5) time for improvement. Outcomes were change in culture, uptake of five strategies associated with lower risk-standardised mortality rates (RSMR) and RSMR. Measures included a validated survey at baseline and at 12 and 24 months (n=223; average response rate 88%); in-depth interviews (n=393 interviews with 197 staff); and RSMR data from the Centers for Medicare and Medicaid Services. We observed significant changes (p<0.05) in culture between baseline and 24 months in the full sample, particularly in learning environment (p<0.001) and senior management support (p<0.001). Qualitative data indicated substantial shifts in these domains as well as psychological safety. Six of the 10 hospitals achieved substantial improvements in culture, and four made less progress. The use of evidence-based strategies also increased significantly (per hospital average of 2.4 strategies at baseline to 3.9 strategies at 24 months; p<0.05). The six hospitals that demonstrated substantial shifts in culture also experienced significantly greater reductions in RSMR than the four hospitals that did not shift culture (reduced RSMR by 1.07 percentage points vs 0.23 percentage points; p=0.03) between 2011-2014 and 2012-2015. Investing in strategies to foster an organisational culture that supports high performance may help hospitals in their efforts to improve clinical outcomes. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Evaluation of the effects of precipitation on ground-water levels from wells in selected alluvial aquifers in Utah and Arizona, 1936-2005

USGS Publications Warehouse

Gardner, Philip M.; Heilweil, Victor M.

2009-01-01

Increased withdrawals from alluvial aquifers of the southwestern United States during the last half-century have intensified the effects of drought on ground-water levels in valleys where withdrawal for irrigation is greatest. Furthermore, during wet periods, reduced withdrawals coupled with increased natural recharge cause rising ground-water levels. In order to manage water resources more effectively, analysis of ground-water levels under the influence of natural and anthropogenic stresses is useful. This report evaluates the effects of precipitation patterns on ground-water levels in areas of Utah and Arizona that have experienced different amounts of ground-water withdrawal. This includes a comparison of water-level records from basins that are hydrogeologically and climatologically similar but have contrasting levels of ground-water development. Hydrologic data, including records of ground-water levels, basin-wide annual ground-water withdrawals, and precipitation were examined from two basins in Utah (Milford and central Sevier) and three in Arizona (Aravaipa Canyon, Willcox, and Douglas). Most water-level records examined in this study from basins experiencing substantial ground-water development (Milford, Douglas, and Willcox) showed strong trends of declining water levels. Other water-level records, generally from the less-developed basins (central Sevier and Aravaipa Canyon) exhibited trends of increasing water levels. These trends are likely the result of accumulating infiltration of unconsumed irrigation water. Water-level records that had significant trends were detrended by subtraction of a low-order polynomial in an attempt to eliminate the variation in the water-level records that resulted from ground-water withdrawal or the application of water for irrigation. After detrending, water-level residuals were correlated with 2- to 10-year moving averages of annual precipitation from representative stations for the individual basins. The water-level residual time series for each well was matched with the 2- to 10-year moving average of annual precipitation with which it was best correlated and the results were compared across basins and hydrologic settings. Analysis of water-level residuals and moving averages of annual precipitation indicate that ground-water levels in the Utah basins respond more slowly to precipitation patterns than those from the Arizona basins. This is attributed to the dominant mechanism of recharge that most directly influences the respective valley aquifers. Substantial recharge in the Utah basins likely originates as infiltrating snowmelt in the mountain block far from the valley aquifer, whereas mountain-front recharge and streambed infiltration of runoff are the dominant recharge mechanisms operating in the Arizona basins. It was determined that the fraction of water-level variation caused by local precipitation patterns becomes more difficult to resolve with increasing effects of ground-water pumping, especially from incomplete records. As the demand for ground water increases in the southwestern United States, long-term records of ground-water levels have the potential to provide valuable information about the precipitation-driven variation in water levels, which has implications to water management related to water availability.

Trends in mortality from 1965 to 2008 across the English north-south divide: comparative observational study

PubMed Central

Muller, Sara; Buchan, Iain E

2011-01-01

Objective To compare all cause mortality between the north and south of England over four decades. Design Population wide comparative observational study of mortality. Setting Five northernmost and four southernmost English government office regions. Population All residents in each year from 1965 to 2008. Main outcome measures Death rate ratios of north over south England by age band and sex, and northern excess mortality (percentage of excess deaths in north compared with south, adjusted for age and sex and examined for annual trends, using Poisson regression). Results During 1965 to 2008 the northern excess mortality remained substantial, at an average of 13.8% (95% confidence interval 13.7% to 13.9%). This geographical inequality was significantly larger for males than for females (14.9%, 14.7% to 15.0% v 12.7%, 12.6% to 12.9%, P<0.001). The inequality decreased significantly but temporarily for both sexes from the early 80s to the late 90s, followed by a steep significant increase from 2000 to 2008. Inequality varied with age, being higher for ages 0-9 years and 40-74 years and lower for ages 10-39 years and over 75 years. Time trends also varied with age. The strongest trend over time by age group was the increase among the 20-34 age group, from no significant northern excess mortality in 1965-95 to 22.2% (18.7% to 26.0%) in 1996-2008. Overall, the north experienced a fifth more premature (<75 years) deaths than the south, which was significant: a pattern that changed only by a slight increase between 1965 and 2008. Conclusion Inequalities in all cause mortality in the north-south divide were severe and persistent over the four decades from 1965 to 2008. Males were affected more than females, and the variation across age groups was substantial. The increase in this inequality from 2000 to 2008 was notable and occurred despite the public policy emphasis in England over this period on reducing inequalities in health. PMID:21325004

Tuning stochastic matrix models with hydrologic data to predict the population dynamics of a riverine fish.

PubMed

Sakaris, Peter C; Irwin, Elise R

2010-03-01

We developed stochastic matrix models to evaluate the effects of hydrologic alteration and variable mortality on the population dynamics of a lotic fish in a regulated river system. Models were applied to a representative lotic fish species, the flathead catfish (Pylodictis olivaris), for which two populations were examined: a native population from a regulated reach of the Coosa River (Alabama, USA) and an introduced population from an unregulated section of the Ocmulgee River (Georgia, USA). Size-classified matrix models were constructed for both populations, and residuals from catch-curve regressions were used as indices of year class strength (i.e., recruitment). A multiple regression model indicated that recruitment of flathead catfish in the Coosa River was positively related to the frequency of spring pulses between 283 and 566 m3/s. For the Ocmulgee River population, multiple regression models indicated that year class strength was negatively related to mean March discharge and positively related to June low flow. When the Coosa population was modeled to experience five consecutive years of favorable hydrologic conditions during a 50-year projection period, it exhibited a substantial spike in size and increased at an overall 0.2% annual rate. When modeled to experience five years of unfavorable hydrologic conditions, the Coosa population initially exhibited a decrease in size but later stabilized and increased at a 0.4% annual rate following the decline. When the Ocmulgee River population was modeled to experience five years of favorable conditions, it exhibited a substantial spike in size and increased at an overall 0.4% annual rate. After the Ocmulgee population experienced five years of unfavorable conditions, a sharp decline in population size was predicted. However, the population quickly recovered, with population size increasing at a 0.3% annual rate following the decline. In general, stochastic population growth in the Ocmulgee River was more erratic and variable than population growth in the Coosa River. We encourage ecologists to develop similar models for other lotic species, particularly in regulated river systems. Successful management of fish populations in regulated systems requires that we are able to predict how hydrology affects recruitment and will ultimately influence the population dynamics of fishes.

Mechanical weathering and rock erosion by climate-dependent subcritical cracking

NASA Astrophysics Data System (ADS)

Eppes, Martha-Cary; Keanini, Russell

2017-06-01

This work constructs a fracture mechanics framework for conceptualizing mechanical rock breakdown and consequent regolith production and erosion on the surface of Earth and other terrestrial bodies. Here our analysis of fracture mechanics literature explicitly establishes for the first time that all mechanical weathering in most rock types likely progresses by climate-dependent subcritical cracking under virtually all Earth surface and near-surface environmental conditions. We substantiate and quantify this finding through development of physically based subcritical cracking and rock erosion models founded in well-vetted fracture mechanics and mechanical weathering, theory, and observation. The models show that subcritical cracking can culminate in significant rock fracture and erosion under commonly experienced environmental stress magnitudes that are significantly lower than rock critical strength. Our calculations also indicate that climate strongly influences subcritical cracking—and thus rock weathering rates—irrespective of the source of the stress (e.g., freezing, thermal cycling, and unloading). The climate dependence of subcritical cracking rates is due to the chemophysical processes acting to break bonds at crack tips experiencing these low stresses. We find that for any stress or combination of stresses lower than a rock's critical strength, linear increases in humidity lead to exponential acceleration of subcritical cracking and associated rock erosion. Our modeling also shows that these rates are sensitive to numerous other environment, rock, and mineral properties that are currently not well characterized. We propose that confining pressure from overlying soil or rock may serve to suppress subcritical cracking in near-surface environments. These results are applicable to all weathering processes.

Psychological factors associated with self-reported sensitivity to mobile phones.

PubMed

Rubin, G James; Cleare, Anthony J; Wessely, Simon

2008-01-01

Some people report symptoms associated with mobile phone use. A minority also report "electrosensitivity," experiencing symptoms following exposure to other electrical devices. Research suggests that electromagnetic fields do not trigger these symptoms. In this study, we examined the differences between these two "sensitive" groups and healthy controls. Fifty-two people who reported sensitivity to mobile phones, 19 people who reported sensitivity to mobile phones and "electrosensitivity," and 60 nonsensitive controls completed a questionnaire assessing the following: primary reason for using a mobile phone, psychological health, symptoms of depression, modern health worries (MHW), general health status, symptom severity, and the presence of other medically unexplained syndromes. Perceived sensitivity was associated with an increased likelihood of using a mobile phone predominantly for work (3% of controls, 13% of those sensitive to mobile phones, and 21% of those reporting "electrosensitivity") and greater MHW concerning radiation [mean (S.D.) on a scale of 1-5: 2.0 (1.0), 2.7 (0.9), and 4.0 (0.8), respectively]. Participants who reported "electrosensitivity" also experienced greater depression, greater worries about tainted food and toxic interventions, worse general health on almost every measure, and a greater number of other medically unexplained syndromes compared to participants from the other two groups. No group differences were observed with regards to psychiatric cases. The data illustrate that patients reporting "electrosensitivity" experience substantially worse health than either healthy individuals or people who report sensitivity to mobile phones but who do not adopt the label "electrosensitivity." Clinicians and researchers would be wise to pay greater attention to this subdivision.

Neuroimaging during Trance State: A Contribution to the Study of Dissociation

PubMed Central

Peres, Julio Fernando; Moreira-Almeida, Alexander; Caixeta, Leonardo; Leao, Frederico; Newberg, Andrew

2012-01-01

Despite increasing interest in pathological and non-pathological dissociation, few researchers have focused on the spiritual experiences involving dissociative states such as mediumship, in which an individual (the medium) claims to be in communication with, or under the control of, the mind of a deceased person. Our preliminary study investigated psychography – in which allegedly “the spirit writes through the medium's hand” – for potential associations with specific alterations in cerebral activity. We examined ten healthy psychographers – five less expert mediums and five with substantial experience, ranging from 15 to 47 years of automatic writing and 2 to 18 psychographies per month – using single photon emission computed tomography to scan activity as subjects were writing, in both dissociative trance and non-trance states. The complexity of the original written content they produced was analyzed for each individual and for the sample as a whole. The experienced psychographers showed lower levels of activity in the left culmen, left hippocampus, left inferior occipital gyrus, left anterior cingulate, right superior temporal gyrus and right precentral gyrus during psychography compared to their normal (non-trance) writing. The average complexity scores for psychographed content were higher than those for control writing, for both the whole sample and for experienced mediums. The fact that subjects produced complex content in a trance dissociative state suggests they were not merely relaxed, and relaxation seems an unlikely explanation for the underactivation of brain areas specifically related to the cognitive processing being carried out. This finding deserves further investigation both in terms of replication and explanatory hypotheses. PMID:23166648

Diazepam-stress interactions in the rat: effects on autoanalgesia and a plus-maze model of anxiety.

PubMed

Taukulis, H K; Goggin, C E

1990-03-01

On six occasions spaced at least a week apart, two groups of rats were subjected to a variety of stressful conditions consisting of a restraint/bright light complex, either alone or in combination with a tail pinch, whole-body inversion, or partial immersion in cold water. One of these groups was injected with diazepam (2.0 mg/kg) 30 min prior to the stressors, while the other group experienced the drug in their home cages the following day. A third group also received the diazepam but was not exposed to the stressors. In three test sessions all animals were injected with either diazepam or saline and were then exposed to a novel stressor: a plus-maze used as a screening device for anxiolytic drugs. This was immediately followed by a tail-flick measure of analgesia. The longest tail-flick latencies, indicating stress-induced analgesia ("autoanalgesia"), were observed in the group that had not been exposed to stress prior to testing. The other two groups exhibited substantially shorter latencies but did not differ from one another, thus showing a "stress inoculation" effect that was uninfluenced by diazepam. In the plus-maze, diazepam tends to increase the amount of time rats will spend in the two exposed arms of the maze relative to the two enclosed arms. This effect was significantly attenuated in the group that had previously experienced the variety of stressors after a diazepam injection, suggesting a learned association between drug and stress that resulted in a diminution of the drug's anxiolytic property.

Living with coeliac disease: a grounded theory study.

PubMed

Rose, C; Howard, R

2014-02-01

Coeliac disease can be controlled only through adherence to a gluten-free diet. This diet is highly restrictive and can be challenging to maintain. It has been linked with elevated levels of psychological distress, including depression, anxiety and social phobia. Narratives on living with coeliac disease were written by 130 adult members of Coeliac UK (mean age 52.7 years; mean time since diagnosis 10.2 years; 67% sample female; 28% male). Qualitative analysis using grounded theory methods identified five key categories: living with widespread ignorance; social invisibility; creating a coeliac community; a changed identity; grief - and accepting the trade-off. A psychosocial model of living with coeliac disease was constructed from the findings, the central category of which was the changed identity of those diagnosed with the condition. Grief was experienced in relation to a loss of the former diet, changed personal and social identities, loss of social confidence and loss of social activities. Grief was generally mitigated over time as adjustments were made to changes in identity and lifestyle. Creating (or becoming part of) a coeliac community was a strategy enabling those with coeliac disease to re-establish their identities and increase social recognition and acceptance of the condition. Gluten-free living entails a substantial restriction of food choice. The losses and changes entailed impact on the personal and social identities of those living with coeliac disease, and on the behaviour of others towards them. Psychosocial interventions focussed on facilitating coping and adjustment may benefit those experiencing difficulties. © 2013 The Authors Journal of Human Nutrition and Dietetics © 2013 The British Dietetic Association Ltd.

The communication atmosphere between physician colleagues: competitive perfectionism or supportive dialogue? A Norwegian study.

PubMed

Akre, V; Falkum, E; Hoftvedt, B O; Aasland, O G

1997-02-01

Open and supportive communication is probably one of the most important promotors of learning, coping and satisfaction at the workplace. The aim of this paper is to describe and predict the communication atmosphere between Norwegian physicians. Twenty statements describing communication, as perceived by the physicians themselves, were presented to a random sample of the members of the Norwegian Medical Association of which more than 90% of the physicians in the country are members (N = 2628). In general, this investigation indicates that the communication atmosphere among Norwegian physicians is characterised by support and mutual respect. More than half of the respondents fully agreed that communication between colleagues in the workplace is marked by solidarity, and that experienced colleagues show respect for the less experienced in both personal and professional matters. Physicians working in hospitals described the communication atmosphere as substantially more selfish and competitive than non-hospital physicians, whilst general practitioners considered the atmosphere between colleagues to be more supportive than non-specialists. In addition, high perceived stress was associated with the perception of a less supportive atmosphere. However, the strongest predictor of the communication atmosphere was clearly the physician's perceived autonomy. The comprehensive retrenchment programmes implemented in Norwegian hospitals during recent years have increased stress and restricted professional autonomy among both physicians and other occupational groups. Our findings indicate that the communication atmosphere necessary to secure continuity of knowledge within the medical profession may have been jeopardised by this process. In the long term, this may prove hazardous to the quality of medical care.

Intraoperative tremor in surgeons and trainees.

PubMed

Verrelli, David I; Qian, Yi; Wilson, Michael K; Wood, James; Savage, Craig

2016-09-01

Tremor may be expected to interfere with the performance of fine motor tasks such as surgery. While tremor is readily quantified in inactive subjects, it is more challenging to measure tremor as the subjects perform complex tasks. The objective of this work was to quantify tremor during the performance of a realistic simulated surgery. Our novel surgical simulator incorporates a force sensor that allows identification and quantification of the intraoperative effects of tremor on the manipulandum. We have collected preliminary data from trainees and experienced surgeons carrying out multiple simulated anastomoses on silicone vessels, mimicking a procedure such as distal coronary anastomosis. We calculated transient and overall tremor intensity, and tested for a hypothesized 'learning effect'. Several of the recordings of intraoperative force data manifested distinctive features corresponding to substantial oscillation in the range of 8-12 Hz. We attribute this to enhanced physiological tremor. These early results indicate a significant reduction in the transmission of surgeon's tremor to the operative field from the first attempt to later attempts (P = 0.039, standardized effect size = 0.91), which may be associated with increasing confidence. This new method does not just quantify tremor, but quantifies the transmission of tremor to a manipulandum in the operative field during high-fidelity simulated coronary surgery. This may be used to assess and provide feedback on the performance of trainees and experienced surgeons, along with other fields in which fine motor skills are of vital importance. © The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Opioid Overdose Experience, Risk Behaviors, and Knowledge in Drug Users from a Rural versus an Urban Setting.

PubMed

Dunn, Kelly E; Barrett, Frederick S; Yepez-Laubach, Claudia; Meyer, Andrew C; Hruska, Bryce J; Petrush, Kathy; Berman, Suzan; Sigmon, Stacey C; Fingerhood, Michael; Bigelow, George E

2016-12-01

Opioid use is highly prevalent in the United States and there has been an increased incidence in the rate of opioid-related overdose. While evidence suggests there are substantial differences in opioid use among rural versus urban settings, the rate of overdose and corresponding frequency of opioid overdose risk behaviors and overdose knowledge between rural and urban settings have not been examined. Individuals with opioid use disorder from rural (N=98) and urban (N=247) settings completed a self-report survey regarding their lifetime history of overdose and overdose risk behaviors. Participants also completed the Brief Opioid Overdose Knowledge (BOOK) questionnaire, a 12-item self-report measure of opioid overdose knowledge. Overall, 35.6% of participants had experienced an overdose, and prevalence of overdose was significantly higher (p<.01) among rural (45.9%) vs. urban (31.6%) participants, though fewer rural participants reported past 30-day risk behaviors. There were few differences observed between the subset of rural and urban participants who had experienced an overdose, and fewer rural participants with a history of overdose reported past 30-day risk behaviors. Both rural and urban participants performed poorly on the BOOK, though the percent of correct responses was lowest among rural participants with a history of overdose. Results demonstrate higher rates of overdose among rural opioid users, though rural participants were less likely to report recent risk behaviors. Results also suggest that knowledge regarding key factors related to opioid overdose is severely lacking, particularly among rural opioid users, which could be a potential target for future intervention efforts.

HiFiVS Modeling of Flow Diverter Deployment Enables Hemodynamic Characterization of Complex Intracranial Aneurysm Cases

PubMed Central

Xiang, Jianping; Damiano, Robert J.; Lin, Ning; Snyder, Kenneth V.; Siddiqui, Adnan H.; Levy, Elad I.; Meng, Hui

2016-01-01

Object Flow diversion via Pipeline Embolization Device (PED) represents the most recent advancement in endovascular therapy of intracranial aneurysms. This exploratory study aims at a proof of concept for an advanced device-modeling tool in conjunction with computational fluid dynamics (CFD) to evaluate flow modification effects by PED in real treatment cases. Methods We performed computational modeling of three PED-treated complex aneurysm cases. Case I had a fusiform vertebral aneurysm treated with a single PED. Case II had a giant internal carotid artery (ICA) aneurysm treated with 2 PEDs. Case III consisted of two tandem ICA aneurysms (a and b) treated by a single PED. Our recently developed high fidelity virtual stenting (HiFiVS) technique was used to recapitulate the clinical deployment process of PEDs in silico for these three cases. Pre- and post-treatment aneurysmal hemodynamics using CFD simulation was analyzed. Changes in aneurysmal flow velocity, inflow rate, and wall shear stress (WSS) (quantifying flow reduction) and turnover time (quantifying stasis) were calculated and compared with clinical outcome. Results In Case I (occluded within the first 3 months), the aneurysm experienced the most drastic aneurysmal flow reduction after PED placement, where the aneurysmal average velocity, inflow rate and average WSS was decreased by 76.3%, 82.5% and 74.0%, respectively, while the turnover time was increased to 572.1% of its pre-treatment value. In Case II (occluded at 6 months), aneurysmal average velocity, inflow rate and average WSS were decreased by 39.4%, 38.6%, and 59.1%, respectively, and turnover time increased to 163.0%. In Case III, Aneurysm III-a (occluded at 6 months) experienced decrease by 38.0%, 28.4%, and 50.9% in aneurysmal average velocity, inflow rate and average WSS, respectively and increase to 139.6% in turnover time, which was quite similar to Aneurysm II. Surprisingly, the adjacent Aneurysm III-b experienced more substantial flow reduction (decrease by 77.7%, 53.0%, and 84.4% in average velocity, inflow rate and average WSS, respectively, and increase to 213.0% in turnover time) than Aneurysm III-a, which qualitatively agreed with angiographic observation at 3-month follow-up. However, Aneurysm III-b remained patent at both 6 months and 9 months. A closer examination of the vascular anatomy of Case III revealed blood draining to the ophthalmic artery off Aneurysm III-b, which may have prevented its complete thrombosis. Conclusion This proof-of-concept study demonstrates that HiFiVE modeling of flow diverter deployment enables detailed characterization of hemodynamic alteration by PED placement. Post-treatment aneurysmal flow reduction may be correlated with aneurysm occlusion outcome. However, predicting aneurysm treatment outcome by flow diverters also requires consideration of other factors including vascular anatomy. PMID:26090829

Contrasting Heat Budget Dynamics During Two La Niña Marine Heat Wave Events Along Northwestern Australia

NASA Astrophysics Data System (ADS)

Xu, Jiangtao; Lowe, Ryan J.; Ivey, Gregory N.; Jones, Nicole L.; Zhang, Zhenling

2018-02-01

Two marine heat wave events along Western Australia (WA) during the alternate austral summer periods of 2010/2011 and 2012/2013, both linked to La Niña conditions, severely impacted marine ecosystems over more than 12° of latitude, which included the unprecedented bleaching of many coral reefs. Although these two heat waves were forced by similar large-scale climate drivers, the warming patterns differed substantially between events. The central coast of WA (south of 22°S) experienced greater warming in 2010/2011, whereas the northwestern coast of WA experienced greater warming in 2012/2013. To investigate how oceanic and atmospheric heat exchange processes drove these different spatial patterns, an analysis of the ocean heat budget was conducted by integrating remote sensing observations, in situ mooring data, and a high-resolution (˜1 km) ocean circulation model (Regional Ocean Modeling System). The results revealed substantial spatial differences in the relative contributions made by heat advection and air-sea heat exchange between the two heat wave events. During 2010/2011, anomalous warming driven by heat advection was present throughout the region but was much stronger south of 22°S where the poleward-flowing Leeuwin Current strengthens. During 2012/2013, air-sea heat exchange had a much more positive (warming) influence on sea surface temperatures (especially in the northwest), and when combined with a more positive contribution of heat advection in the north, this can explain the regional differences in warming between these two La Niña-associated marine heat wave events.

Community preferences for health states associated with intimate partner violence.

PubMed

Wittenberg, Eve; Lichter, Erika L; Ganz, Michael L; McCloskey, Laura A

2006-08-01

One in 4 women is affected by intimate partner violence in her lifetime. This article reports on a cross-sectional survey to estimate community preferences for health states resulting from intimate partner violence. A secondary analysis was conducted of data from a convenience sample of 93 abused and 138 nonabused women (231 total) recruited for in-person interviews from hospital outpatient department waiting rooms in metropolitan Boston, Massachusetts. SF-12 data were converted to utilities to describe community-perspective preferences for health states associated with intimate partner violence. Linear regression analysis was used to explore the association between violence and utility while controlling for other health and demographic factors. Median utility for intimate partner violence was between 0.58 and 0.63 on a scale of 0 (equivalent to death) to 1.0 (equivalent to optimal health), with a range from 0.64 to 0.66 for less severe violence to 0.53 to 0.62 for more severe violence. The data do not reveal whether violence itself is responsible for lower utility or whether a constellation of factors contributes to disutility experienced by women victims of abuse. The utility of health states experienced by women exposed to intimate partner violence is substantially diminished compared with optimal health and even other health conditions. These values quantify the substantial negative health impact of the experience of intimate partner violence in terms that allow comparison across diseases. They can be used in cost-effectiveness analyses to identify the benefits and potential returns from resources allocated to violence prevention and intervention efforts.

Communication-related affective, behavioral, and cognitive reactions in speakers with spasmodic dysphonia.

PubMed

Watts, Christopher R; Vanryckeghem, Martine

2017-12-01

To investigate the self-perceived affective, behavioral, and cognitive reactions associated with communication of speakers with spasmodic dysphonia as a function of employment status. Prospective cross-sectional investigation. 148 Participants with spasmodic dysphonia (SD) completed an adapted version of the Behavior Assessment Battery (BAB-Voice), a multidimensional assessment of self-perceived reactions to communication. The BAB-Voice consisted of four subtests: the Speech Situation Checklist for A) Emotional Reaction (SSC-ER) and B) Speech Disruption (SSC-SD), C) the Behavior Checklist (BCL), and D) the Communication Attitude Test for Adults (BigCAT). Participants were assigned to groups based on employment status (working versus retired). Descriptive comparison of the BAB-Voice in speakers with SD to previously published non-dysphonic speaker data revealed substantially higher scores associated with SD across all four subtests. Multivariate Analysis of Variance (MANOVA) revealed no significantly different BAB-Voice subtest scores as a function of SD group status (working vs. retired). BAB-Voice scores revealed that speakers with SD experienced substantial impact of their voice disorder on communication attitude, coping behaviors, and affective reactions in speaking situations as reflected in their high BAB scores. These impacts do not appear to be influenced by work status, as speakers with SD who were employed or retired experienced similar levels of affective and behavioral reactions in various speaking situations and cognitive responses. These findings are consistent with previously published pilot data. The specificity of items assessed by means of the BAB-Voice may inform the clinician of valid patient-centered treatment goals which target the impairment extended beyond the physiological dimension. 2b.

Sexual abuse in childhood and physical and mental health in adulthood: an Australian population study.

PubMed

Najman, Jake M; Nguyen, My Linh T; Boyle, Frances M

2007-10-01

Although childhood sexual abuse (CSA) is associated with a wide range of health problems later in life, there is also evidence of substantial individual differences. This study describes the mental and physical health of a population sample of Australians, randomly selected from the Commonwealth electoral roll, who have reported their CSA histories. Some 58% of those located from the electoral roll agreed to a telephone interview (n=1,784). Health status was measured using the Short Form 36 questionnaire. Men who had experienced non-penetrative and penetrative sexual abuse in childhood had 2.25 (95% CI=1.32-3.82) and 5.93 (95% CI=2.72-12.95) times respectively the rate of impaired mental health, but no higher rates of impaired physical health. Women who had experienced non-penetrative and penetrative sexual abuse in childhood had 1.87 (95% CI=1.19-2.95) and 3.15 (95% CI=1.87-5.33) times respectively the rate of impaired mental health and 1.87 (95% CI=1.19-2.92) and 2.31 (95% CI=1.34-3.97) times respectively the rate of impaired physical health. However, participants who had experienced CSA were no less likely than those who had not experienced CSA to be in optimum physical and mental health. None of the possible confounding or moderating variables tested appeared to mitigate the impact of CSA on health outcomes. Those with the highest levels of mental and physical health appear to be unaffected by the experience of CSA.

Peer Victimization in Fifth Grade and Health in Tenth Grade

PubMed Central

Elliott, Marc N.; Klein, David J.; Tortolero, Susan R.; Mrug, Sylvie; Peskin, Melissa F.; Davies, Susan L.; Schink, Elizabeth T.; Schuster, Mark A.

2014-01-01

BACKGROUND AND OBJECTIVES: Children who experience bullying, a type of peer victimization, show worse mental and physical health cross-sectionally. Few studies have assessed these relationships longitudinally. We examined longitudinal associations of bullying with mental and physical health from elementary to high school, comparing effects of different bullying histories. METHODS: We analyzed data from 4297 children surveyed at 3 time points (fifth, seventh, and tenth grades) in 3 cities. We used multivariable regressions to test longitudinal associations of bullying with mental and physical health by comparing youth who experienced bullying in both the past and present, experienced bullying in the present only, experienced bullying in the past only, or did not experience bullying. RESULTS: Bullying was associated with worse mental and physical health, greater depression symptoms, and lower self-worth over time. Health was significantly worse for children with both past and present bullying experiences, followed by children with present-only experiences, children with past-only experiences, and children with no experiences. For example, 44.6% of children bullied in both the past and present were at the lowest decile of psychosocial health, compared with 30.7% of those bullied in the present only (P = .005), 12.1% of those bullied in the past only (P < .001), and 6.5% of those who had not been bullied (P < .001). CONCLUSIONS: Both chronic and current bullying are associated with substantially worse health. Clinicians who recognize bullying when it first starts could intervene to reverse the downward health trajectory experienced by youth who are repeated targets. PMID:24534401

HIV-1 genetic diversity and antiretroviral drug resistance among individuals from Roraima state, northern Brazil

PubMed Central

Leão, Renato Augusto Carvalho; Granja, Fabiana; Naveca, Felipe Gomes

2017-01-01

The HIV-1 epidemic in Brazil has spread towards the Northern country region, but little is known about HIV-1 subtypes and prevalence of HIV strains with resistance mutations to antiretrovirals in some of the Northern states. HIV-1 protease (PR) and reverse transcriptase (RT) sequences were obtained from 73 treatment-naive and -experienced subjects followed between 2013 and 2014 at a public health reference unit from Roraima, the northernmost Brazilian state. The most prevalent HIV-1 clade observed in the study population was the subtype B (91%), followed by subtype C (9%). Among 12 HIV-1 strains from treatment-naïve patients, only one had a transmitted drug resistance mutation for NNRTI. Among 59 treatment-experienced patients, 12 (20%) harbored HIV-1 strains with acquired drug resistance mutations (ADRM) that reduce the susceptibility to two classes of antiretroviral drugs (NRTI and NNRTI or NRTI and PI), and five (8%) harbored HIV-1 strains with ADRM that reduced susceptibility to only one class of antiretroviral drugs (NNRTI or PI). No patients harboring HIV strains with reduced susceptibility to all three classes of antiretroviral drugs were detected. A substantial fraction of treatment-experienced patients with (63%) and without (70%) ADRM had undetectable plasma viral loads (<40 copies/ml) at the time of sampling. Among treatment-experienced with plasma viral loads above 2,000 copies/ml, 44% displayed no ADRM. This data showed that the HIV-1 epidemic in Roraima displayed a much lower level of genetic diversity and a lower prevalence of ADRM than that described in other Brazilian states. PMID:28301548

Clinical and muscle biopsy findings in Norwegian paediatric patients with limb girdle muscular dystrophy 2I.

PubMed

Rasmussen, Magnhild; Scheie, David; Breivik, Noralv; Mork, Marit; Lindal, Sigurd

2014-05-01

To describe patients diagnosed with limb girdle muscular dystrophy 2I (LGMD2I) in our paediatric departments between 2004 and 2012. The hospital charts of 17 patients presenting for evaluation at a mean age of 7.8 years (range 1-13 years) were retrospectively reviewed. With one exception, all patients were homozygous for the common mutation c.826C>A in the FKRP gene. Three patients experienced transient pronounced weakness as toddlers. Fatigue and muscle pain were most prominent, weakness less so, in children presenting at an older age. The degree of severity varied substantially. In certain cases, increased creatine kinase was an incidental finding. All walked independently by 18 months. When last evaluated at a mean age of 14.3 years (range 3.5-18 years), five patients were part-time wheelchair users. One patient was then treated for a cardiomyopathy. Creatine kinase was consistently increased, except presymptomatic in one patient. Muscle biopsies showed focal acute and chronic myopathic changes and pathological expression of α-dystroglycan. No consistent relationship between clinical function and the degree of morphological pathology was found. LGMD2I is a relevant differential diagnosis when creatine kinase is increased in children presenting with fatigue, muscle pain and sometimes weakness. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Mechanics of evolutionary digit reduction in fossil horses (Equidae).

PubMed

McHorse, Brianna K; Biewener, Andrew A; Pierce, Stephanie E

2017-08-30

Digit reduction is a major trend that characterizes horse evolution, but its causes and consequences have rarely been quantitatively tested. Using beam analysis on fossilized centre metapodials, we tested how locomotor bone stresses changed with digit reduction and increasing body size across the horse lineage. Internal bone geometry was captured from 13 fossil horse genera that covered the breadth of the equid phylogeny and the spectrum of digit reduction and body sizes, from Hyracotherium to Equus To account for the load-bearing role of side digits, a novel, continuous measure of digit reduction was also established-toe reduction index (TRI). Our results show that without accounting for side digits, three-toed horses as late as Parahippus would have experienced physiologically untenable bone stresses. Conversely, when side digits are modelled as load-bearing, species at the base of the horse radiation through Equus probably maintained a similar safety factor to fracture stress. We conclude that the centre metapodial compensated for evolutionary digit reduction and body mass increases by becoming more resistant to bending through substantial positive allometry in internal geometry. These results lend support to two historical hypotheses: that increasing body mass selected for a single, robust metapodial rather than several smaller ones; and that, as horse limbs became elongated, the cost of inertia from the side toes outweighed their utility for stabilization or load-bearing. © 2017 The Author(s).

Severe summer heatwave and drought strongly reduced carbon uptake in Southern China

DOE PAGES

Yuan, Wenping; Cai, Wenwen; Chen, Yang; ...

2016-01-07

Increasing heatwave and drought events can potentially alter the carbon cycle. Few studies have investigated the impacts of hundred-year return heatwaves and droughts, as those events are rare. In the summer of 2013, southern China experienced its strongest drought and heatwave on record for the past 113 years. We show that the record-breaking heatwave and drought lasted two months (from July to August), significantly reduced the satellite-based vegetation index and gross primary production, substantially altered the regional carbon cycle, and produced the largest negative crop yield anomaly since 1960. The event resulted in a net reduction of 101.54 Tg Cmore » in carbon sequestration in the region during these two months, which was 39–53% of the annual net carbon sink of China’s terrestrial ecosystems (190–260 Tg C yr -1). Moreover, model experiments showed that heatwaves and droughts consistently decreased ecosystem vegetation primary production but had opposite impacts on ecosystem respiration (TER), with increased TER by 6.78 ± 2.15% and decreased TER by 15.34 ± 3.57% assuming only changed temperature and precipitation, respectively. As a result, in light of increasing frequency and severity of future heatwaves and droughts, our study highlights the importance of accounting for the impacts of heatwaves and droughts in assessing the carbon sequestration in terrestrial ecosystems.« less

Substance use in adulthood following adolescent self-harm: a population-based cohort study

PubMed Central

Moran, P; Coffey, C; Romaniuk, H; Degenhardt, L; Borschmann, R; Patton, G C

2015-01-01

Objective To determine whether adolescents who self-harm are at increased risk of heavy and dependent substance use in adulthood. Method Fifteen-year prospective cohort study of a random sample of 1943 adolescents recruited from secondary schools across the state of Victoria, Australia. Data pertaining to self-harm and substance use was obtained at seven waves of follow-up, from mean age 15.9 years to mean age 29.1 years. Results Substance use and self-harm were strongly associated during the adolescent years (odds ratio (OR): 3.3, 95% CI 2.1–5.0). Moreover, adolescent self-harmers were at increased risk of substance use and dependence syndromes in young adulthood. Self-harm predicted a four-fold increase in the odds of multiple dependence syndromes (sex- and wave-adjusted OR: 4.2, 95% CI: 2.7–6.6). Adjustment for adolescent anxiety/depression attenuated but did not eliminate most associations. Adolescent substance use confounded all associations, with the exception of multiple dependence syndromes, which remained robustly associated with adolescent self-harm (fully adjusted odds ratio: 2.0, 95% CI: 1.2–3.2). Conclusion Adolescent self-harm is an independent risk factor for multiple dependence syndromes in adulthood. This level of substance misuse is likely to contribute substantially to the premature mortality and disease burden experienced by individuals who self-harm. PMID:24954250

The response of Antarctic sea ice algae to changes in pH and CO2.

PubMed

McMinn, Andrew; Müller, Marius N; Martin, Andrew; Ryan, Ken G

2014-01-01

Ocean acidification substantially alters ocean carbon chemistry and hence pH but the effects on sea ice formation and the CO2 concentration in the enclosed brine channels are unknown. Microbial communities inhabiting sea ice ecosystems currently contribute 10-50% of the annual primary production of polar seas, supporting overwintering zooplankton species, especially Antarctic krill, and seeding spring phytoplankton blooms. Ocean acidification is occurring in all surface waters but the strongest effects will be experienced in polar ecosystems with significant effects on all trophic levels. Brine algae collected from McMurdo Sound (Antarctica) sea ice was incubated in situ under various carbonate chemistry conditions. The carbon chemistry was manipulated with acid, bicarbonate and bases to produce a pCO2 and pH range from 238 to 6066 µatm and 7.19 to 8.66, respectively. Elevated pCO2 positively affected the growth rate of the brine algal community, dominated by the unique ice dinoflagellate, Polarella glacialis. Growth rates were significantly reduced when pH dropped below 7.6. However, when the pH was held constant and the pCO2 increased, growth rates of the brine algae increased by more than 20% and showed no decline at pCO2 values more than five times current ambient levels. We suggest that projected increases in seawater pCO2, associated with OA, will not adversely impact brine algal communities.

Severe summer heatwave and drought strongly reduced carbon uptake in Southern China

PubMed Central

Yuan, Wenping; Cai, Wenwen; Chen, Yang; Liu, Shuguang; Dong, Wenjie; Zhang, Haicheng; Yu, Guirui; Chen, Zhuoqi; He, Honglin; Guo, Weidong; Liu, Dan; Liu, Shaoming; Xiang, Wenhua; Xie, Zhenghui; Zhao, Zhonghui; Zhou, Guomo

2016-01-01

Increasing heatwave and drought events can potentially alter the carbon cycle. Few studies have investigated the impacts of hundred-year return heatwaves and droughts, as those events are rare. In the summer of 2013, southern China experienced its strongest drought and heatwave on record for the past 113 years. We show that the record-breaking heatwave and drought lasted two months (from July to August), significantly reduced the satellite-based vegetation index and gross primary production, substantially altered the regional carbon cycle, and produced the largest negative crop yield anomaly since 1960. The event resulted in a net reduction of 101.54 Tg C in carbon sequestration in the region during these two months, which was 39–53% of the annual net carbon sink of China’s terrestrial ecosystems (190–260 Tg C yr−1). Moreover, model experiments showed that heatwaves and droughts consistently decreased ecosystem vegetation primary production but had opposite impacts on ecosystem respiration (TER), with increased TER by 6.78 ± 2.15% and decreased TER by 15.34 ± 3.57% assuming only changed temperature and precipitation, respectively. In light of increasing frequency and severity of future heatwaves and droughts, our study highlights the importance of accounting for the impacts of heatwaves and droughts in assessing the carbon sequestration in terrestrial ecosystems. PMID:26739761

Severe summer heatwave and drought strongly reduced carbon uptake in Southern China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yuan, Wenping; Cai, Wenwen; Chen, Yang

Increasing heatwave and drought events can potentially alter the carbon cycle. Few studies have investigated the impacts of hundred-year return heatwaves and droughts, as those events are rare. In the summer of 2013, southern China experienced its strongest drought and heatwave on record for the past 113 years. We show that the record-breaking heatwave and drought lasted two months (from July to August), significantly reduced the satellite-based vegetation index and gross primary production, substantially altered the regional carbon cycle, and produced the largest negative crop yield anomaly since 1960. The event resulted in a net reduction of 101.54 Tg Cmore » in carbon sequestration in the region during these two months, which was 39–53% of the annual net carbon sink of China’s terrestrial ecosystems (190–260 Tg C yr -1). Moreover, model experiments showed that heatwaves and droughts consistently decreased ecosystem vegetation primary production but had opposite impacts on ecosystem respiration (TER), with increased TER by 6.78 ± 2.15% and decreased TER by 15.34 ± 3.57% assuming only changed temperature and precipitation, respectively. As a result, in light of increasing frequency and severity of future heatwaves and droughts, our study highlights the importance of accounting for the impacts of heatwaves and droughts in assessing the carbon sequestration in terrestrial ecosystems.« less

Drainage Evolution during the Uplift of the Central Anatolia Plateau

NASA Astrophysics Data System (ADS)

Brocard, G. Y.; Meijers, M. J.; Willenbring, J. K.; Kaymakci, N.; Whitney, D. L.

2015-12-01

The Central Anatolian plateau formed in the past 8-6 Myrs, associated to a change in tectonic regime, from contraction to extensional escape tectonics. We have examined the response of the river drainage of Central Anatolia to the rise of the plateau uplift and to the formation of the Anatolian microplate, tracking changes in drainage organization. Anatolia experienced widespread rock uplift and erosion in the Late Oligocene, generating a narrow, steep, and quickly eroding mountain range above the future southern plateau margin. A regionally widespread marine transgression resulted from wholesale foundering of this orogen in Early Miocene time. Widespread planation surfaces overlapped by Miocene marine carbonates bevel this topography, indicating that relief had been reduced to a low elevation pedimented landscape by the end of the Middle Miocene. Plateau uplift initiated around 11 My ago in Eastern Anatolia; it was echoed in Central Anatolia by a short-lived phase of contraction and localized uplifts that predate escape tectonics and mark the beginning of the current topographic differentiation of the southern plateau margin. The through-going drainage network inherited disintegrated, and a vast zone of inward drainage formed at the location of the future plateau interior. Between 8 and 6 My, the southern plateau margin (i.e. the Tauride Mountains) emerged. δ18O analyses on lacustrine and pedogenic carbonates show that the southern plateau margin, if not the plateau interior, had experienced enough uplift by 5 My to generate a substantial rain shadow over the plateau interior. Being disconnected from the regional base level from the start, the plateau interior was able to rise without experiencing substantial dissection. It reconnected to all surrounding sediment sinks (Mediterranean Sea, Black Sea and Persian Gulf) over the past 5 My. We discuss the mechanisms that have driven this reconnection. Bottom-up processes of integration such as drainage divide retreat did not produce any major changes. Top-down processes such as lake overflow and avulsion achieved most of the re-integration. They result from more positive precipitation/evaporation balances, either due to elevation change during plateau uplift or due to tectonic fragmentation of depocenters during the development of escape tectonics.

Declining brown-headed cowbird (Molothrus ater) populations are associated with landscape-specific reductions in brood parasitism and increases in songbird productivity

Treesearch

W. Andrew Cox; Frank R., III Thompson; Brian Root; John Faaborg; Csaba Moskat

2012-01-01

Many songbird species have experienced significant population declines, partly because of brood parasitism by the Brown-headed Cowbird (Molothrus ater), which is positively associated with increasing landscape forest cover in the midwestern United States. However, cowbirds are also experiencing long-term population declines, which should reduce...

High Expectations for Higher Education? Perceptions of College and Experiences of Stress Prior to and through the College Career

ERIC Educational Resources Information Center

Krieg, Dana Balsink

2013-01-01

Increasing numbers of students are experiencing difficulty adjusting to college. Violated expectations of college may increase the stress experienced across the college career. Therefore, 36 college students were assessed prior to matriculation, during the first year and during the senior year. Expectations and experiences of academics, social…

Hydroclimate of North Island of New Zealand during the last 45,000 Years.

NASA Astrophysics Data System (ADS)

Piatrunia, N.; Shanahan, T. M.; Augustinus, P. M.; Atkins, D.; Huang, Y.

2016-12-01

Southern hemisphere climate variability and its connection with past changes in the northern hemisphere remains poorly understood. While climate conditions in the polar regions are well-studied, the spatial and temporal resolution of existing southern hemisphere mid-latitude records is limited. New Zealand provides an ideal location for the preservation of high-resolution multi-proxy records in lacustrine cores and the analysis of mid-latitude climate throughout the Holocene and beyond. Here, we present a 45,000-year record of plant wax dD (a proxy for precipitation) and branched GDGT-derived temperatures from Lake Pupuke, on the North Island of New Zealand (36°78.30'S, 174°76.70'E) in order to better constrain changes in the climate of the southern hemisphere mid latitudes. We find that during the last glacial the North Island experienced colder and drier conditions, with temperatures that were > 3.5°C cooler than those experienced during the Holocene. Plant wax dD values vary substantially during the glacial interval, with the most enriched values occurring at 21 kyr and 24.5 kyr. Shifts to more arid conditions during these intervals were associated with intensification of the SH westerlies and the northward migration of the subtropical (STF), subpolar (SPF) and polar fronts (PF). The Lake Pupuke record suggests that deglaciation of New Zealand initiated at 18 kyr, with gradual increases in temperature. dD values continue to decrease gradually through the deglaciation, suggesting a linear response of precipitation to insolation forcing. However, temperature increases abruptly during the Bolling-Allerod warming - coincident with changes in the northern hemisphere. Together, these data suggest a decoupling of the controls on deglacial circulation and temperature changes, with important implications for our understanding of the mechanisms of deglacial climate changes in the southern hemisphere mid-latitudes and the interpretation of proxy records from this region.

Making the invisible, visible: a cross-sectional study of late presentation to HIV/AIDS services among men who have sex with men from a large urban center of Brazil.

PubMed

MacCarthy, Sarah; Brignol, Sandra; Reddy, Manasa; Nunn, Amy; Dourado, Ines

2014-12-22

Late presentation to testing, treatment and continued care has detrimental impacts on the health of HIV-positive individuals as well as their sexual partners' health. Men who have sex with men (MSM) experience disproportionately high rates of HIV both globally and in Brazil. However, the factors that inhibit linkage to care among MSM remain unclear. We conducted a cross-sectional study of HIV-positive MSM (n = 740) enrolled in HIV/AIDS services in a large urban center of Brazil from August 2010 to June 2011. Descriptive, bivariate and multivariate statistics were conducted using STATA 12 to examine the relationship between a range of variables and late presentation, defined as having a first CD4 count <350 cells/mm3. Within the sample, the prevalence of LP was 63.1%. Men who self-identified as heterosexual (AOR 1.54 and 95% CI 1.08 - 2.20) compared to men who self-identified as homosexual and bisexual were at increased odds of late presentation. Additionally, men age 30 and older (AOR 1.56, 95% CI 1.01 - 2.43) compared to individuals age 18-29 experienced increased odds of late presentation among MSM. The prevalence of LP in this population was higher than noted in the global literature on LP among MSM. Heterosexual men and older age individuals experienced substantial barriers to HIV care. The stigma around same-sex behaviors and the current focus of HIV prevention and treatment campaigns on younger age individuals may limit patients' and providers' awareness of the risk for HIV and access to available services. In addition to addressing HIV-specific barriers to care, developing effective strategies to reduce late presentation in Brazil will require addressing social factors - such as stigma against diverse sexualities - to concretely identify and eliminate barriers to available services. Only in so doing can we make currently invisible people, visible.

Post-Extinction Ecological Recovery of Marine Life Modes

NASA Astrophysics Data System (ADS)

Park, C.; de la Torre, N. G.; Heim, N.; Payne, J.

2016-12-01

A mass extinction is defined by a substantial increase in extinction rates, resulting in a loss of taxonomic and ecological diversity. Bush et al. (2007) defined ecological life modes as the feeding, motility, and tiering habits and organized them in a six-by-six "eco-cube" in which each section represented a life mode. In our research, we analyzed the ecological recovery of each life mode after the five mass extinctions. Using a fossil marine genera database, we compiled five heat maps that depict the recovery of the life modes by plotting the diversity of genera in each life mode two intervals before and five intervals after each mass extinction interval. New life modes seem to appear either immediately following or three or more intervals after a mass extinction, which indicates that ecological recovery is not a gradual process, but rather occurs in a punctuated manner. Furthermore, the "filling order" of new life modes differ in each extinction. However, some seem to have defined patterns, such as the Ordovician, where earlier post-extinction intervals experienced an increase in the diversity of erect (tiering) ecospaces, followed by that of surficial and shallow infaunal life modes. The Devonian mass extinction followed a similar pattern as the end Ordovician where erect organisms came first followed by surficial, deep-infaunal, and pelagic life modes. Conversely, intervals following the end-Permian mass extinction experienced a recovery in pelagic, freely-moving life modes, followed by a recovery in infaunal organisms and an explosion in semi-infaunal, erect, surficial, and pelagic ecospaces in the Ladinian. New life modes in the Triassic and Cretaceous mass extinctions did not seem to generate in a distinct pattern. Overall, we conclude that recovery patterns are unique depending on the cause of each mass extinction, and that any general tendency in post-extinction ecological recovery was most likely overridden by the environmental condition of the recovery intervals.

Health Insurance Benefit Design and Healthcare Utilization in Northern Rural China

PubMed Central

Wang, Hong; Liu, Yu; Zhu, Yan; Xue, Lei; Dale, Martha; Sipsma, Heather; Bradley, Elizabeth

2012-01-01

Background Poverty due to illness has become a substantial social problem in rural China since the collapse of the rural Cooperative Medical System in the early 1980s. Although the Chinese government introduced the New Rural Cooperative Medical Schemes (NRCMS) in 2003, the associations between different health insurance benefit package designs and healthcare utilization remain largely unknown. Accordingly, we sought to examine the impact of health insurance benefit design on health care utilization. Methods and Findings We conducted a cross-sectional study using data from a household survey of 15,698 members of 4,209 randomly-selected households in 7 provinces, which were representative of the provinces along the north side of the Yellow River. Interviews were conducted face-to-face and in Mandarin. Our analytic sample included 9,762 respondents from 2,642 households. In each household, respondents indicated the type of health insurance benefit that the household had (coverage for inpatient care only or coverage for both inpatient and outpatient care) and the number of outpatient visits in the 30 days preceding the interview and the number of hospitalizations in the 365 days preceding the household interview. People who had both outpatient and inpatient coverage compared with inpatient coverage only had significantly more village-level outpatient visits, township-level outpatient visits, and total outpatient visits. Furthermore, the increased utilization of township and village-level outpatient care was experienced disproportionately by people who were poorer, whereas the increased inpatient utilization overall and at the county level was experienced disproportionately by people who were richer. Conclusion The evidence from this study indicates that the design of health insurance benefits is an important policy tool that can affect the health services utilization and socioeconomic equity in service use at different levels. Without careful design, health insurance may not benefit those who are most in need of financial protection from health services expenses. PMID:23185616

Health insurance benefit design and healthcare utilization in northern rural China.

PubMed

Wang, Hong; Liu, Yu; Zhu, Yan; Xue, Lei; Dale, Martha; Sipsma, Heather; Bradley, Elizabeth

2012-01-01

Poverty due to illness has become a substantial social problem in rural China since the collapse of the rural Cooperative Medical System in the early 1980s. Although the Chinese government introduced the New Rural Cooperative Medical Schemes (NRCMS) in 2003, the associations between different health insurance benefit package designs and healthcare utilization remain largely unknown. Accordingly, we sought to examine the impact of health insurance benefit design on health care utilization. We conducted a cross-sectional study using data from a household survey of 15,698 members of 4,209 randomly-selected households in 7 provinces, which were representative of the provinces along the north side of the Yellow River. Interviews were conducted face-to-face and in Mandarin. Our analytic sample included 9,762 respondents from 2,642 households. In each household, respondents indicated the type of health insurance benefit that the household had (coverage for inpatient care only or coverage for both inpatient and outpatient care) and the number of outpatient visits in the 30 days preceding the interview and the number of hospitalizations in the 365 days preceding the household interview. People who had both outpatient and inpatient coverage compared with inpatient coverage only had significantly more village-level outpatient visits, township-level outpatient visits, and total outpatient visits. Furthermore, the increased utilization of township and village-level outpatient care was experienced disproportionately by people who were poorer, whereas the increased inpatient utilization overall and at the county level was experienced disproportionately by people who were richer. The evidence from this study indicates that the design of health insurance benefits is an important policy tool that can affect the health services utilization and socioeconomic equity in service use at different levels. Without careful design, health insurance may not benefit those who are most in need of financial protection from health services expenses.

Paleoclimatological perspective on the hydrometeorology of the Mekong Basin

NASA Astrophysics Data System (ADS)

Räsänen, T. A.; Lehr, C.; Mellin, I.; Ward, P. J.; Kummu, M.

2012-11-01

During recent decades the Mekong River has experienced substantial interannual variations between droughts and major floods. The causes of these variations have been sought in climate change and dam construction. However, so far little research has addressed whether these recent variations are significantly different to long-term variations in the past. Hence, the aim of our paper is to place the recent variations between droughts and floods into a historical and paleoclimatological context. To achieve this we analysed the Mekong's meteorological conditions over the period 1300-2005 with a basin scale approach by using the Monsoon Asia Drought Atlas (MADA), which is a Palmer Drought Severity Index (PDSI) dataset derived from tree-ring growth records. The correlation analyses, both in time and frequency domains, showed correlation between MADA and the Mekong's discharge over the period 1910-2005 which suggests that MADA can be used as proxy for the hydrometeorology of the Mekong Basin. We found that the meteorological conditions of the Mekong varied at multi-annual, decadal and centennial scales over the study period. We found two especially distinct features: firstly, multi-annual and decadal variation between prolonged wet and dry epochs; and secondly, epochs with higher or lower interannual variability between very dry and wet years. Furthermore we found two epochs with exceptionally large interannual variability, one at the beginning of 17th century and the other in the post 1950 epoch. Both epochs are characterized by distinct increases in variability between very wet and dry years. The variability in the post 1950 epoch is much higher compared to any of the other epochs included in this study. Thus, during recent decades the climate in the Mekong has exhibited features that have not been experienced for at least several centuries. These findings call for further climate research, particularly regarding increased climate variability, and resilient adaptation and development approaches in the basin.

The Quality Indicator Survey: background, implementation, and widespread change.

PubMed

Lin, Michael K; Kramer, Andrew M

2013-01-01

The Quality Indicator Survey (QIS) is the most comprehensive regulatory change to the nursing home survey process since the Omnibus Budget Reconciliation Act of 1987 (OBRA-87). In this article we describe the policy evolution that led to the QIS, summarize the QIS method and implementation, and profile the QIS survey results. Following over a decade of development, in 2007 the Centers for Medicare and Medicaid Services (CMS) began the national rollout of QIS. The intent was to improve consistency in the nursing home survey and to render the survey process more resident-centered and aligned with the intent of OBRA-87. We reviewed policy reports and firsthand accounts from the lead developer of the QIS methodology and leader of the national training contract for QIS. Changes in survey findings are profiled based on analysis of the publicly available Nursing Home Compare database from 2004 to 2010. Nineteen states implemented the QIS between 2007 and 2010, with nearly 20% of U.S. nursing homes receiving QIS surveys in 2010. Nursing homes surveyed with the QIS received more survey deficiencies on average than in the traditional survey; however, average numbers of deficiencies across states became more similar over the early implementation of QIS, with lower-than-average geographic areas experiencing increases and higher-than-average geographic areas experiencing decreases in survey deficiencies. The explicit and structured questioning of residents in the QIS is associated with increases in deficiencies related to choice, dignity, dental care, and nurse staffing. We describe ways in which the QIS affected the regulatory agencies, providers, and resident communities, although these effects are difficult to quantify. CMS's implementation of QIS is a significant step toward a more resident-centered, comprehensive, and consistent survey process. Substantial changes, however, are required not only among regulators but also among nursing homes. We argue that these new expectations and norms surrounding quality assessment and quality assurance are an important component of achieving culture change in U.S. nursing homes.

The complete chloroplast DNA sequences of the charophycean green algae Staurastrum and Zygnema reveal that the chloroplast genome underwent extensive changes during the evolution of the Zygnematales

PubMed Central

Turmel, Monique; Otis, Christian; Lemieux, Claude

2005-01-01

Background The Streptophyta comprise all land plants and six monophyletic groups of charophycean green algae. Phylogenetic analyses of four genes from three cellular compartments support the following branching order for these algal lineages: Mesostigmatales, Chlorokybales, Klebsormidiales, Zygnematales, Coleochaetales and Charales, with the last lineage being sister to land plants. Comparative analyses of the Mesostigma viride (Mesostigmatales) and land plant chloroplast genome sequences revealed that this genome experienced many gene losses, intron insertions and gene rearrangements during the evolution of charophyceans. On the other hand, the chloroplast genome of Chaetosphaeridium globosum (Coleochaetales) is highly similar to its land plant counterparts in terms of gene content, intron composition and gene order, indicating that most of the features characteristic of land plant chloroplast DNA (cpDNA) were acquired from charophycean green algae. To gain further insight into when the highly conservative pattern displayed by land plant cpDNAs originated in the Streptophyta, we have determined the cpDNA sequences of the distantly related zygnematalean algae Staurastrum punctulatum and Zygnema circumcarinatum. Results The 157,089 bp Staurastrum and 165,372 bp Zygnema cpDNAs encode 121 and 125 genes, respectively. Although both cpDNAs lack an rRNA-encoding inverted repeat (IR), they are substantially larger than Chaetosphaeridium and land plant cpDNAs. This increased size is explained by the expansion of intergenic spacers and introns. The Staurastrum and Zygnema genomes differ extensively from one another and from their streptophyte counterparts at the level of gene order, with the Staurastrum genome more closely resembling its land plant counterparts than does Zygnema cpDNA. Many intergenic regions in Zygnema cpDNA harbor tandem repeats. The introns in both Staurastrum (8 introns) and Zygnema (13 introns) cpDNAs represent subsets of those found in land plant cpDNAs. They represent 16 distinct insertion sites, only five of which are shared by the two zygnematalean genomes. Three of these insertions sites have not been identified in Chaetosphaeridium cpDNA. Conclusion The chloroplast genome experienced substantial changes in overall structure, gene order, and intron content during the evolution of the Zygnematales. Most of the features considered earlier as typical of land plant cpDNAs probably originated before the emergence of the Zygnematales and Coleochaetales. PMID:16236178

Land use change exacerbates tropical South American drought by sea surface temperature variability

NASA Astrophysics Data System (ADS)

Lee, Jung-Eun; Lintner, Benjamin R.; Boyce, C. Kevin; Lawrence, Peter J.

2011-10-01

Observations of tropical South American precipitation over the last three decades indicate an increasing rainfall trend to the north and a decreasing trend to the south. Given that tropical South America has experienced significant land use change over the same period, it is of interest to assess the extent to which changing land use may have contributed to the precipitation trends. Simulations of the National Center for Atmospheric Research Community Atmosphere Model (NCAR CAM3) analyzed here suggest a non-negligible impact of land use on this precipitation behavior. While forcing the model by imposed historical sea surface temperatures (SSTs) alone produces a plausible north-south precipitation dipole over South America, NCAR CAM substantially underestimates the magnitude of the observed southern decrease in rainfall unless forcing associated with human-induced land use change is included. The impact of land use change on simulated precipitation occurs primarily during the local dry season and in regions of relatively low annual-mean rainfall, as the incidence of very low monthly-mean accumulations (<10 mm/month) increases significantly when land use change is imposed. Land use change also contributes to the simulated temperature increase by shifting the surface turbulent flux partitioning to favor sensible over latent heating. Moving forward, continuing pressure from deforestation in tropical South America will likely increase the occurrence of significant drought beyond what would be expected by anthropogenic warming alone and in turn compound biodiversity decline from habitat loss and fragmentation.

Pharmacological management of chronic heart failure in adults: a review of the literature.

PubMed

Auty, Richard

2004-03-01

Heart failure is a common, life threatening condition encountered in patients of all ages and in all clinical settings. It may be due to any of a wide variety of causes - in Malawi, cardiomyopathies, hypertension and rheumatic heart disease are probably the commonest causes of heart failure. In more affluent societies, ischaemic heart disease is an important factor. Chronic heart failure (CHF) causes significant morbidity: it reduces exercise capacity, interferes with sleep and produces unsightly and uncomfortable oedema. The syndrome also carries substantial mortatity, worse than that of many malignant tumours: 20 -30% of patients with mild or moderately severe heart failure will die every year if left untreated. The life expectancy of a patient with untreated severe heart failure is only about 6 months. Table 1 explains the symptomatic classification of the severity of heart failure. Objective measurements of cardiac function, such as Left Ventricular Ejection Fraction (LYEF) or chamber filling pressures, correlate poorly with symptoms and New York Heart Association (NYHA) classification. Many of the problems experienced by a patient with heart failure are due to a 'vicious circle' of events in which pathophysiological responses to the falling cardiac output cause further deterioration in cardiac function over time. These responses include ventricular remodeling, neurohumoural activation (increased sympathetic activity; increased atrial natriuretic peptide; increased angiotensin II), increased activity of the renin-angiotensin-aldosterone system (RAAS) causing fluid retention, vasoconstriction and sodium retention. [Table: see text].

Land Use and Land Cover Change in the Qinghai Lake Region of the Tibetan Plateau and Its Impact on Ecosystem Services

PubMed Central

Gong, Jian; Yang, Jianxin; Tang, Wenwu

2017-01-01

Exploration of land use and land cover change (LULCC) and its impacts on ecosystem services in Tibetan plateau is valuable for landscape and environmental conservation. In this study, we conduct spatial analysis on empirical land use and land cover data in the Qinghai Lake region for 1990, 2000, and 2010 and simulate land cover patterns for 2020. We then evaluate the impacts of LULCC on ecosystem service value (ESV), and analyze the sensitivity of ESV to LULCC to identify the ecologically sensitive area. Our results indicate that, from 1990 to 2010, the area of forest and grassland increased while the area of unused land decreased. Simulation results suggest that the area of grassland and forest will continue to increase and the area of cropland and unused land will decrease for 2010–2020. The ESV in the study area increased from 694.50 billion Yuan in 1990 to 714.28 billion Yuan in 2000, and to 696.72 billion Yuan in 2020. Hydrology regulation and waste treatment are the top two ecosystem services in this region. The towns surrounding the Qinghai Lake have high ESVs, especially in the north of the Qinghai Lake. The towns with high ESV sensitivity to LULCC are located in the northwest, while the towns in the north of the Qinghai Lake experienced substantial increase in sensitivity index from 2000–2010 to 2010–2020, especially for three regulation services and aesthetic landscape provision services. PMID:28754029

Land Use and Land Cover Change in the Qinghai Lake Region of the Tibetan Plateau and Its Impact on Ecosystem Services.

PubMed

Gong, Jian; Li, Jingye; Yang, Jianxin; Li, Shicheng; Tang, Wenwu

2017-07-21

Exploration of land use and land cover change (LULCC) and its impacts on ecosystem services in Tibetan plateau is valuable for landscape and environmental conservation. In this study, we conduct spatial analysis on empirical land use and land cover data in the Qinghai Lake region for 1990, 2000, and 2010 and simulate land cover patterns for 2020. We then evaluate the impacts of LULCC on ecosystem service value (ESV), and analyze the sensitivity of ESV to LULCC to identify the ecologically sensitive area. Our results indicate that, from 1990 to 2010, the area of forest and grassland increased while the area of unused land decreased. Simulation results suggest that the area of grassland and forest will continue to increase and the area of cropland and unused land will decrease for 2010-2020. The ESV in the study area increased from 694.50 billion Yuan in 1990 to 714.28 billion Yuan in 2000, and to 696.72 billion Yuan in 2020. Hydrology regulation and waste treatment are the top two ecosystem services in this region. The towns surrounding the Qinghai Lake have high ESVs, especially in the north of the Qinghai Lake. The towns with high ESV sensitivity to LULCC are located in the northwest, while the towns in the north of the Qinghai Lake experienced substantial increase in sensitivity index from 2000-2010 to 2010-2020, especially for three regulation services and aesthetic landscape provision services.

Marketing actions can modulate neural representations of experienced pleasantness.

PubMed

Plassmann, Hilke; O'Doherty, John; Shiv, Baba; Rangel, Antonio

2008-01-22

Despite the importance and pervasiveness of marketing, almost nothing is known about the neural mechanisms through which it affects decisions made by individuals. We propose that marketing actions, such as changes in the price of a product, can affect neural representations of experienced pleasantness. We tested this hypothesis by scanning human subjects using functional MRI while they tasted wines that, contrary to reality, they believed to be different and sold at different prices. Our results show that increasing the price of a wine increases subjective reports of flavor pleasantness as well as blood-oxygen-level-dependent activity in medial orbitofrontal cortex, an area that is widely thought to encode for experienced pleasantness during experiential tasks. The paper provides evidence for the ability of marketing actions to modulate neural correlates of experienced pleasantness and for the mechanisms through which the effect operates.

Disparities in work-related homicide rates in selected retail industries in the United States, 2003–2008

PubMed Central

Menéndez, Cammie Chaumont; Konda, Srinivas; Hendricks, Scott; Amandus, Harlan

2015-01-01

Problem Segments within the retail industry have a substantially higher rate of work-related fatality due to workplace violence compared to the retail industry overall. Certain demographic subgroups may be at higher risk. Method National traumatic injury surveillance data were analyzed to characterize the distribution of fatality rates due to workplace violence among selected retail workers in the United States from 2003 through 2008. Results Overall, the highest fatality rates due to work-related homicide occurred among men, workers aged ≥ 65 years, black, Asian, foreign-born and Southern workers. Among foreign-born workers, those aged 16–24 years, non-Hispanic whites and Asians experienced substantially higher fatality rates compared to their native-born counterparts. Conclusions The burden of work-related homicide in the retail industry falls more heavily on several demographic groups, including racial minorities and the foreign-born. Further research should examine the causes of these trends. Interventions designed to prevent workplace violence should target these groups. PMID:23398701

Demographics and run timing of adult Lost River (Deltistes luxatus) and shortnose (Chasmistes brevirostris) suckers in Upper Klamath Lake, Oregon, 2011

USGS Publications Warehouse

Hewitt, David A.; Janney, Eric C.; Hayes, Brian S.; Harris, Alta C.

2012-01-01

Despite relatively high survival in most years, both species have experienced substantial declines in the abundance of spawning fish because losses from mortality have not been balanced by recruitment of new individuals. Although capture-recapture data indicate substantial recruitment of new individuals into the adult spawning populations for SNS and river spawning LRS in some years, size data do not corroborate these estimates. In fact, fork length data indicate that all populations are largely comprised of fish that were present in the late 1990s and early 2000s. As a result, the status of the endangered sucker populations in Upper Klamath Lake remains worrisome, and the situation is most dire for shortnose suckers. Future investigations should explore the connections between sucker recruitment and survival and various environmental factors, such as water quality and disease. Our monitoring program provides a robust platform for estimating vital population parameters, evaluating the status of the populations, and assessing the effectiveness of conservation and recovery efforts.

Temporal biodiversity change in transformed landscapes: a southern African perspective

PubMed Central

Chown, Steven L.

2010-01-01

Landscape transformation by humans is virtually ubiquitous, with several suggestions being made that the world's biomes should now be classified according to the extent and nature of this transformation. Even those areas that are thought to have a relatively limited human footprint have experienced substantial biodiversity change. This is true of both marine and terrestrial systems of southern Africa, a region of high biodiversity and including several large conservation areas. Global change drivers have had substantial effects across many levels of the biological hierarchy as is demonstrated in this review, which focuses on terrestrial systems. Interactions among drivers, such as between climate change and invasion, and between changing fire regimes and invasion, are complicating attribution of change effects and management thereof. Likewise CO2 fertilization is having a much larger impact on terrestrial systems than perhaps commonly acknowledged. Temporal changes in biodiversity, and the seeming failure of institutional attempts to address them, underline a growing polarization of world views, which is hampering efforts to address urgent conservation needs. PMID:20980320

Future loss of Arctic sea-ice cover could drive a substantial decrease in California's rainfall.

PubMed

Cvijanovic, Ivana; Santer, Benjamin D; Bonfils, Céline; Lucas, Donald D; Chiang, John C H; Zimmerman, Susan

2017-12-05

From 2012 to 2016, California experienced one of the worst droughts since the start of observational records. As in previous dry periods, precipitation-inducing winter storms were steered away from California by a persistent atmospheric ridging system in the North Pacific. Here we identify a new link between Arctic sea-ice loss and the North Pacific geopotential ridge development. In a two-step teleconnection, sea-ice changes lead to reorganization of tropical convection that in turn triggers an anticyclonic response over the North Pacific, resulting in significant drying over California. These findings suggest that the ability of climate models to accurately estimate future precipitation changes over California is also linked to the fidelity with which future sea-ice changes are simulated. We conclude that sea-ice loss of the magnitude expected in the next decades could substantially impact California's precipitation, thus highlighting another mechanism by which human-caused climate change could exacerbate future California droughts.

Women's Experiences of Preeclampsia: Australian Action on Preeclampsia Survey of Women and Their Confidants

PubMed Central

East, C.; Conway, K.; Pollock, W.; Frawley, N.; Brennecke, S.

2011-01-01

Introduction. The experience of normal pregnancy is often disrupted for women with preeclampsia (PE). Materials and Methods. Postal survey of the 112 members of the consumer group, Australian Action on Pre-Eclampsia (AAPEC). Results. Surveys were returned by 68 women (61% response rate) and from 64 (57%) partners, close relatives or friends. Respondents reported experiencing pre-eclampsia (n = 53), eclampsia (n = 5), and/or Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP syndrome) (n = 26). Many women had no knowledge of PE prior to diagnosis (77%) and, once diagnosed, did not appreciate how serious or life threatening it was (50%). Women wanted access to information about PE. Their experience contributed substantial anxiety towards future pregnancies. Partners/friends/relatives expressed fear for the woman and/or her baby and had no prior understanding of PE. Conclusions. The PE experience had a substantial effect on women, their confidants, and their babies and affected their approach to future pregnancies. Access to information about PE was viewed as very important. PMID:21547089

Environmental Health and Safety Hazards Experienced by Home Health Care Providers: A Room-by-Room Analysis.

PubMed

Polivka, Barbara J; Wills, Celia E; Darragh, Amy; Lavender, Steven; Sommerich, Carolyn; Stredney, Donald

2015-11-01

The number of personnel providing in-home health care services is increasing substantially. The unique configuration of environmental hazards in individual client homes has a significant impact on the safety and health of home health care providers (HHPs). This mixed-methods study used data from a standardized questionnaire, focus groups, and individual interviews to explore environmental health and safety hazards encountered by HHPs in client homes. The participant sample (N = 68) included nurses, aides, therapists, and owners/managers from a variety of geographic locations. The most often-reported hazards were trip/slip/lift hazards, biohazards, and hazards from poor air quality, allergens, pests and rodents, and fire and burns. Frequency of identified key hazards varied by room, that is, kitchen (e.g., throw rugs, water on floor), bathroom (e.g., tight spaces for client handling), bedroom (e.g., bed too low), living room (e.g., animal waste), and hallway (e.g., clutter). Findings indicate the need for broader training to enable HHPs to identify and address hazards they encounter in client homes. © 2015 The Author(s).

Nutrition transition, food retailing and health equity in Thailand.

PubMed

Kelly, Matthew; Banwell, Cathy; Dixon, Jane; Seubsman, Sam-Ang; Yiengprugsawan, Vasoontara; Sleigh, Adrian

2010-12-01

AIM: Here we examine the influence of changes in food retailing, the food supply and the associated nutrition transition on health equity in Thailand, a middle income country experiencing rapid economic development. METHODS: The dietary transition underway in Thailand is reviewed along with theories regarding convergence to a globalised energy dense obesogenic diet and subsequent socio-economically related dietary divergence along with the implications for health inequity. RESULTS: Thailand is part way through a dietary, nutrition and health transition. The food distribution and retailing system is now 50% controlled by modern supermarkets and convenience stores. The problem of increasing availability of calorie dense foods is especially threatening because a substantial proportion of the adult population is short statured due to child malnutrition. Obesity is an emerging problem and for educated Thai women has already developed an inverse relationship to socio-economic status as found in high income countries. CONCLUSIONS: Thailand has reached an important point in its nutrition transition. The challenge for the Thai government and population is to boost affordable healthy diets and to avoid the socio-economic inequity of nutritional outcomes observed in many rich countries.

Salt marsh persistence is threatened by predicted sea-level rise

NASA Astrophysics Data System (ADS)

Crosby, Sarah C.; Sax, Dov F.; Palmer, Megan E.; Booth, Harriet S.; Deegan, Linda A.; Bertness, Mark D.; Leslie, Heather M.

2016-11-01

Salt marshes buffer coastlines and provide critical ecosystem services from storm protection to food provision. Worldwide, these ecosystems are in danger of disappearing if they cannot increase elevation at rates that match sea-level rise. However, the magnitude of loss to be expected is not known. A synthesis of existing records of salt marsh elevation change was conducted in order to consider the likelihood of their future persistence. This analysis indicates that many salt marshes did not keep pace with sea-level rise in the past century and kept pace even less well over the past two decades. Salt marshes experiencing higher local sea-level rise rates were less likely to be keeping pace. These results suggest that sea-level rise will overwhelm most salt marshes' capacity to maintain elevation. Under the most optimistic IPCC emissions pathway, 60% of the salt marshes studied will be gaining elevation at a rate insufficient to keep pace with sea-level rise by 2100. Without mitigation of greenhouse gas emissions this potential loss could exceed 90%, which will have substantial ecological, economic, and human health consequences.

Economic conditions, hypertension, and cardiovascular disease: analysis of the Icelandic economic collapse.

PubMed

Birgisdóttir, Kristín Helga; Jónsson, Stefán Hrafn; Ásgeirsdóttir, Tinna Laufey

2017-12-01

Previous research has found a positive short-term relationship between the 2008 collapse and hypertension in Icelandic males. With Iceland's economy experiencing a phase of economic recovery, an opportunity to pursue a longer-term analysis of the collapse has emerged. Using data from a nationally representative sample, fixed-effect estimations and mediation analyses were performed to explore the relationship between the Icelandic economic collapse in 2008 and the longer-term impact on hypertension and cardiovascular health. A sensitivity analysis was carried out with pooled logit models estimated as well as an alternative dependent variable. Our attrition analysis revealed that results for cardiovascular diseases were affected by attrition, but not results from estimations on the relationship between the economic crisis and hypertension. When compared to the boom year 2007, our results point to an increased probability of Icelandic women having hypertension in the year 2012, when the Icelandic economy had recovered substantially from the economic collapse in 2008. This represents a deviation from pre-crisis trends, thus suggesting a true economic-recovery impact on hypertension.

Environmental Health and Safety Hazards Experienced by Home Health Care Providers

PubMed Central

Polivka, Barbara J.; Wills, Celia E.; Darragh, Amy; Lavender, Steven; Sommerich, Carolyn; Stredney, Donald

2015-01-01

The number of personnel providing in-home health care services is increasing substantially. The unique configuration of environmental hazards in individual client homes has a significant impact on the safety and health of home health care providers (HHPs). This mixed-methods study used data from a standardized questionnaire, focus groups, and individual interviews to explore environmental health and safety hazards encountered by HHPs in client homes. The participant sample (N = 68) included nurses, aides, therapists, and owners/managers from a variety of geographic locations. The most often-reported hazards were trip/slip/lift hazards, biohazards, and hazards from poor air quality, allergens, pests and rodents, and fire and burns. Frequency of identified key hazards varied by room, that is, kitchen (e.g., throw rugs, water on floor), bathroom (e.g., tight spaces for client handling), bedroom (e.g., bed too low), living room (e.g., animal waste), and hallway (e.g., clutter). Findings indicate the need for broader training to enable HHPs to identify and address hazards they encounter in client homes. PMID:26268486

Nutrition transition, food retailing and health equity in Thailand

PubMed Central

Kelly, Matthew; Banwell, Cathy; Dixon, Jane; Seubsman, Sam-ang; Yiengprugsawan, Vasoontara; Sleigh, Adrian

2012-01-01

Aim Here we examine the influence of changes in food retailing, the food supply and the associated nutrition transition on health equity in Thailand, a middle income country experiencing rapid economic development. Methods The dietary transition underway in Thailand is reviewed along with theories regarding convergence to a globalised energy dense obesogenic diet and subsequent socio-economically related dietary divergence along with the implications for health inequity. Results Thailand is part way through a dietary, nutrition and health transition. The food distribution and retailing system is now 50% controlled by modern supermarkets and convenience stores. The problem of increasing availability of calorie dense foods is especially threatening because a substantial proportion of the adult population is short statured due to child malnutrition. Obesity is an emerging problem and for educated Thai women has already developed an inverse relationship to socio-economic status as found in high income countries. Conclusions Thailand has reached an important point in its nutrition transition. The challenge for the Thai government and population is to boost affordable healthy diets and to avoid the socio-economic inequity of nutritional outcomes observed in many rich countries. PMID:22442643

Homogenization patterns of the world’s freshwater fish faunas

PubMed Central

Villéger, Sébastien; Blanchet, Simon; Beauchard, Olivier; Oberdorff, Thierry; Brosse, Sébastien

2011-01-01

The world is currently undergoing an unprecedented decline in biodiversity, which is mainly attributable to human activities. For instance, nonnative species introduction, combined with the extirpation of native species, affects biodiversity patterns, notably by increasing the similarity among species assemblages. This biodiversity change, called taxonomic homogenization, has rarely been assessed at the world scale. Here, we fill this gap by assessing the current homogenization status of one of the most diverse vertebrate groups (i.e., freshwater fishes) at global and regional scales. We demonstrate that current homogenization of the freshwater fish faunas is still low at the world scale (0.5%) but reaches substantial levels (up to 10%) in some highly invaded river basins from the Nearctic and Palearctic realms. In these realms experiencing high changes, nonnative species introductions rather than native species extirpations drive taxonomic homogenization. Our results suggest that the “Homogocene era” is not yet the case for freshwater fish fauna at the worldwide scale. However, the distressingly high level of homogenization noted for some biogeographical realms stresses the need for further understanding of the ecological consequences of homogenization processes. PMID:22025692

Homogenization patterns of the world's freshwater fish faunas.

PubMed

Villéger, Sébastien; Blanchet, Simon; Beauchard, Olivier; Oberdorff, Thierry; Brosse, Sébastien

2011-11-01

The world is currently undergoing an unprecedented decline in biodiversity, which is mainly attributable to human activities. For instance, nonnative species introduction, combined with the extirpation of native species, affects biodiversity patterns, notably by increasing the similarity among species assemblages. This biodiversity change, called taxonomic homogenization, has rarely been assessed at the world scale. Here, we fill this gap by assessing the current homogenization status of one of the most diverse vertebrate groups (i.e., freshwater fishes) at global and regional scales. We demonstrate that current homogenization of the freshwater fish faunas is still low at the world scale (0.5%) but reaches substantial levels (up to 10%) in some highly invaded river basins from the Nearctic and Palearctic realms. In these realms experiencing high changes, nonnative species introductions rather than native species extirpations drive taxonomic homogenization. Our results suggest that the "Homogocene era" is not yet the case for freshwater fish fauna at the worldwide scale. However, the distressingly high level of homogenization noted for some biogeographical realms stresses the need for further understanding of the ecological consequences of homogenization processes.

Effects of oxaliplatin on mouse myenteric neurons and colonic motility

PubMed Central

Wafai, Linah; Taher, Mohammadali; Jovanovska, Valentina; Bornstein, Joel C.; Dass, Crispin R.; Nurgali, Kulmira

2013-01-01

Oxaliplatin, an anti-cancer chemotherapeutic agent used for the treatment of colorectal cancer, commonly causes gastrointestinal side-effects such as constipation, diarrhoea, nausea, and vomiting. Damage to enteric neurons may underlie some of these gastrointestinal side-effects, as the enteric nervous system (ENS) controls functions of the bowel. In this study, neuronal loss and changes to the structure and immunoreactivity of myenteric neuronal nitric oxide synthase (nNOS) neurons were examined in colonic segments from mice following exposure to oxaliplatin ex vivo and following repeated intraperitoneal injections of oxaliplatin over 3 weeks in vivo, using immunohistochemistry and confocal microscopy. Significant morphological alterations and increases in the proportion of NOS-immunoreactive (IR) neurons were associated with both short-term oxaliplatin exposure and long-term oxaliplatin administration, confirming that oxaliplatin causes changes to the myenteric neurons. Long-term oxaliplatin administration induced substantial neuronal loss that was correlated with a reduction in both the frequency and propagation speed of colonic migrating motor complexes (CMMCs) in vitro. Similar changes probably produce some symptoms experienced by patients undergoing oxaliplatin treatment. PMID:23486839

Challenging the Fructose Hypothesis: New Perspectives on Fructose Consumption and Metabolism123

PubMed Central

White, John S.

2013-01-01

The field of sugar metabolism, and fructose metabolism in particular, has experienced a resurgence of interest in the past decade. The “fructose hypothesis” alleges that the fructose component common to all major caloric sweeteners (sucrose, high-fructose corn syrup, honey, and fruit juice concentrates) plays a unique and causative role in the increasing rates of cardiovascular disease, hypertension, diabetes, cancer, and nonalcoholic fatty liver disease. This review challenges the fructose hypothesis by comparing normal U.S. levels and patterns of fructose intake with contemporary experimental models and looking for substantive cause-and-effect evidence from real-world diets. It is concluded that 1) fructose intake at normal population levels and patterns does not cause biochemical outcomes substantially different from other dietary sugars and 2) extreme experimental models that feature hyperdosing or significantly alter the usual dietary glucose-to-fructose ratio are not predictive of typical human outcomes or useful to public health policymakers. It is recommended that granting agencies and journal editors require more physiologically relevant experimental designs and clinically important outcomes for fructose research. PMID:23493541

Barriers to the implementation of management systems: lessons from the past.

PubMed

Gardner, D

2000-01-01

There is a substantial body of evidence, both empirical and anecdotal, concerning factors associated with the success and failure of management systems. Given the increasing interest in management systems for occupational health and safety, quality, and the environment, it is worth looking at some of these factors in order to learn from them and plan for the future. One of the most comprehensive sources of information about factors that can make a management system succeed or fail lies in the material written about systems that improve the quality of products and services. Such systems were extremely widespread during the 1970s and 1980s but are now much less often cited or studied by Australian organisations. One of the reasons underlying the present relative lack of emphasis is that such programs, both here and overseas, experienced a failure rate of between 85% and 95%. While it may seem unlikely that occupational health and safety (OHS) and environmental management systems will experience similar failure rates, it is still worthwhile to look at what went wrong with other systems and to learn from these experiences.

Sleep intensity and the evolution of human cognition.

PubMed

Samson, David R; Nunn, Charles L

2015-01-01

Over the past four decades, scientists have made substantial progress in understanding the evolution of sleep patterns across the Tree of Life. Remarkably, the specifics of sleep along the human lineage have been slow to emerge. This is surprising, given our unique mental and behavioral capacity and the importance of sleep for individual cognitive performance. One view is that our species' sleep architecture is in accord with patterns documented in other mammals. We promote an alternative view, that human sleep is highly derived relative to that of other primates. Based on new and existing evidence, we specifically propose that humans are more efficient in their sleep patterns than are other primates, and that human sleep is shorter, deeper, and exhibits a higher proportion of REM than expected. Thus, we propose the sleep intensity hypothesis: Early humans experienced selective pressure to fulfill sleep needs in the shortest time possible. Several factors likely served as selective pressures for more efficient sleep, including increased predation risk in terrestrial environments, threats from intergroup conflict, and benefits arising from increased social interaction. Less sleep would enable longer active periods in which to acquire and transmit new skills and knowledge, while deeper sleep may be critical for the consolidation of those skills, leading to enhanced cognitive abilities in early humans. © 2015 Wiley Periodicals, Inc.

Turf algae-mediated coral damage in coastal reefs of Belize, Central America.

PubMed

Wild, Christian; Jantzen, Carin; Kremb, Stephan Georg

2014-01-01

Many coral reefs in the Caribbean experienced substantial changes in their benthic community composition during the last decades. This often resulted in phase shifts from scleractinian coral dominance to that by other benthic invertebrate or algae. However, knowledge about how the related role of coral-algae contacts may negatively affect corals is scarce. Therefore, benthic community composition, abundance of algae grazers, and the abundance and character of coral-algae contacts were assessed in situ at 13 Belizean reef sites distributed along a distance gradient to the Belizean mainland (12-70 km): Mesoamerican Barrier Reef (inshore), Turneffe Atoll (inner and outer midshore), and Lighthouse Reef (offshore). In situ surveys revealed significantly higher benthic cover by scleractinian corals at the remote Lighthouse Reef (26-29%) when compared to the other sites (4-19%). The abundance of herbivorous fish and the sea urchin Diadema antillarum significantly increased towards the offshore reef sites, while the occurrence of direct coral-algae contacts consequently increased significantly with decreasing distance to shore. About 60% of these algae contacts were harmful (exhibiting coral tissue damage, pigmentation change, or overgrowth) for corals (mainly genera Orbicella and Agaricia), particularly when filamentous turf algae were involved. These findings provide support to the hypothesis that (turf) algae-mediated coral damage occurs in Belizean coastal, near-shore coral reefs.

Caregiver mental health and potentially harmful caregiving behavior: the central role of caregiver anger.

PubMed

Macneil, Gordon; Kosberg, Jordan I; Durkin, Daniel W; Dooley, W Keith; Decoster, Jamie; Williamson, Gail M

2010-02-01

Caregivers feeling stress and experiencing mental health problems can be at risk for engaging in abusive acts against elderly care recipients. Potentially harmful behavior (PHB) was used as a measure of caregivers' engagement in, or fear of engagement in, behavior that places dependent care recipients at risk of physical and/or psychological maltreatment and may be seen as an antecedent of, or a proxy for, identifiably abusive behavior. The study examined the ability of anger to mediate and moderate the relations of depression, resentment, and anxiety with PBH. Data are from the first wave of the second Family Relationships in Late Life study of caregivers of community-dwelling elderly care recipients with whom they coreside. Caregivers (N = 417) completed face-to-face interviews. Anger was found to mediate the relation between anxiety and PHB. Anger both mediates and moderates the relations of both depression and resentment with PHB in a dynamic way such that the mediating effect of anger increases substantially with increased scores on both depression and resentment. Identifying anger levels among caregivers who report symptoms of depression is warranted. Reducing depression in caregivers who report high levels of anger may result in reductions of PHB. Screening for resentment is warranted, as the relation between resentment and anger is similar to that between depression and anger.

Rapid emergence of atherosclerosis in Asia: a systematic review of coronary atherosclerotic heart disease epidemiology and implications for prevention and control strategies.

PubMed

Wong, Martin C S; Zhang, De Xing; Wang, Harry H X

2015-08-01

There is a global epidemic of coronary heart disease (CHD) caused by atherosclerosis. We discussed its emergence, underlying reasons, and implications for prevention and control strategies in Asia. Most countries in Asia are experiencing the challenges from CHD, with the mortality rate varying from 103 to 366 per 100 000 adult populations, reported by recently published studies. Raised population cholesterol levels played a pivotal role. Men, older adults, and those with dyslipidemia, hypertension, and diabetes were high-risk individuals. During the past decade, there was a marked rising trend of atherosclerosis-related burden particularly in Eastern Asia where an alarming increase of 117.2 and 115.3% of total deaths and disability adjusted life-years, respectively, were observed. The rise of CHD could be attributed to unhealthy lifestyles, clinical-risk factors, psychosocial factors, and public health transitions. Ageing, urbanization, and increase in prosperity may serve as underlying key drivers. The burden of CHD is substantial, whereas contributors are multifactorial. This grand challenge should be a top priority for injecting healthcare resources. The formulation of public health measures will need to adopt an integrated and life-course approach, based on the need and risks of different population subgroups in Asia.

Suicide among immigrants in Europe--a systematic literature review.

PubMed

Spallek, Jacob; Reeske, Anna; Norredam, Marie; Nielsen, Signe Smith; Lehnhardt, Jessica; Razum, Oliver

2015-02-01

Concerns about increased suicide risk among immigrants to European countries have been raised. We review the scientific literature on differences in suicide among immigrants compared with the majority populations in Europe's major immigration countries. We searched the databases PubMed and PsycINFO for peer-reviewed epidemiological studies published in 1990-2011, which compared suicide risks of adult immigrant groups with the risks of the majority population in European countries. Hits were screened by two researchers. We included 24 studies in the review. No generalizable pattern of suicide among immigrants was found. Immigrants from countries in which suicide risks are particularly high, i.e. countries in Northern and Eastern Europe, experienced higher suicide rates relative to groups without migration background. Gender and age differences were observed. Young female immigrants from Turkey, East Africa and South Asia are a risk group. Immigrants 'bring along' their suicide risk, at least for the initial period they spend in the immigration country. Health-care planners and providers need to be aware of this 'imported risks'. However, most immigrant groups do not have an increased suicide risk relative to the local-born population; some may even experience substantially lower risks. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

A filmless radiology department in a full digital regional hospital: quantitative evaluation of the increased quality and efficiency.

PubMed

Nitrosi, Andrea; Borasi, Giovanni; Nicoli, Franco; Modigliani, Gino; Botti, Andrea; Bertolini, Marco; Notari, Pietro

2007-06-01

Reggio Emilia hospital installed Picture Archiving and Communications Systems (PACS) as the final step towards a completely digital clinical environment completing the HIS/EMR and 1,400 web/terminals for patient information access. Financial benefits throughout the hospital were assessed upfront and measured periodically. Key indicators (radiology exam turnaround time, number of radiology procedures performed, inpatients length of stay before and after the PACS implementation, etc.) were analyzed and values were statistically tested to assess workflow and productivity improvements. The hospital went "filmless" in 28 weeks. Between the half of 2004 and the respective period in 2003, overall Radiology Department productivity increased by 12%, TAT improved by more than 60%. Timelier patient care resulted in decreased lengths of stay. Neurology alone experienced a 12% improvement in average patient stay. To quantify the impact of PACS on the average hospital stays and the expected productivity benefits to inpatient productivity were used a "high level" and a "detailed" business model. Annual financial upsides have exceeded $1.9 millions/year. A well-planned PACS deployment simplifies imaging workflow and improves patient care throughout the hospital while delivering substantial financial benefits. Staff buy-in was the key in this process and on-going training and process monitoring are a must.

The Sticking Point in the Bench Press, the Squat, and the Deadlift: Similarities and Differences, and Their Significance for Research and Practice.

PubMed

Kompf, Justin; Arandjelović, Ognjen

2017-04-01

Since it was first observed, and especially so in recent years, the phenomenon of the so-called "sticking point" in resistance training has attracted a substantial amount of sports and exercise science research. Broadly speaking, the sticking point is understood as the position in the range of motion of a lift at which a disproportionately large increase in the difficulty associated with continuing the lift is experienced. Hence the sticking point is inherently the performance bottleneck, and is also associated with an increased chance of exercise form deterioration or breakdown. Understanding the aspects of lifting performance which should be analysed in order to pinpoint the cause of a specific sticking point and therefore devise an effective training strategy to overcome it is of pervasive importance to strength practitioners, and is conducive to injury avoidance and continued progress. In this paper, we survey a range of physiological and biomechanical mechanisms which contribute to the development of sticking points, and then, led by this insight, review and analyse the findings of the existing observational research on the occurrence of sticking points in three ubiquitous exercises: the bench press, the squat, and the deadlift. The findings of our analysis should be used to inform future research and current resistance training practice.

Eliciting preferences for medical devices in South Korea: A discrete choice experiment.

PubMed

Lee, Hye-Jae; Bae, Eun-Young

2017-03-01

This study aims to identify the attributes that contribute to the value of medical devices and quantify the relative importance of them using a discrete choice experiment. Based on a literature review and expert consultation, seven attributes and their levels were identified-severity of disease (2), availability of substitutes (2), improvement in procedure (3), improvement in clinical outcomes (2), increase in survival (2), improvement in quality of life (3), and cost (4). Among 576 hypothetical profiles, optimal choice sets with 20 choices were developed and experts experienced in health technology assessment and reimbursement decision making in South Korea were surveyed. A total of 102 respondents participated in the survey. The results of the random-effect probit model showed that among the seven attributes, six, except for improvement in procedure, had a significant impact on respondents' choices on medical devices. Respondents were willing to pay the highest amount for devices that provided substantial improvements in quality of life, followed by increased survival, improved clinical outcome, treatment without substitutes, and technology for treating severe diseases. The findings of this experiment will inform decision-makers of the relative importance of the criteria and help them in reimbursement decision making of medical devices. Copyright © 2017 Elsevier B.V. All rights reserved.

Common reef-building coral in the Northern Red Sea resistant to elevated temperature and acidification

PubMed Central

Horwitz, Noa; Bodin, Julia; Giovani, Maria-Evangelia; Escrig, Stéphane; Meibom, Anders; Fine, Maoz

2017-01-01

Coral reefs are currently experiencing substantial ecological impoverishment as a result of anthropogenic stressors, and the majority of reefs are facing immediate risk. Increasing ocean surface temperatures induce frequent coral mass bleaching events—the breakdown of the nutritional photo-symbiosis with intracellular algae (genus: Symbiodinium). Here, we report that Stylophora pistillata from a highly diverse reef in the Gulf of Aqaba showed no signs of bleaching despite spending 1.5 months at 1–2°C above their long-term summer maximum (amounting to 11 degree heating weeks) and a seawater pH of 7.8. Instead, their symbiotic dinoflagellates exhibited improved photochemistry, higher pigmentation and a doubling in net oxygen production, leading to a 51% increase in primary productivity. Nanoscale secondary ion mass spectrometry imaging revealed subtle cellular-level shifts in carbon and nitrogen metabolism under elevated temperatures, but overall host and symbiont biomass proxies were not significantly affected. Now living well below their thermal threshold in the Gulf of Aqaba, these corals have been evolutionarily selected for heat tolerance during their migration through the warm Southern Red Sea after the last ice age. This may allow them to withstand future warming for a longer period of time, provided that successful environmental conservation measures are enacted across national boundaries in the region. PMID:28573008

Common reef-building coral in the Northern Red Sea resistant to elevated temperature and acidification.

PubMed

Krueger, Thomas; Horwitz, Noa; Bodin, Julia; Giovani, Maria-Evangelia; Escrig, Stéphane; Meibom, Anders; Fine, Maoz

2017-05-01

Coral reefs are currently experiencing substantial ecological impoverishment as a result of anthropogenic stressors, and the majority of reefs are facing immediate risk. Increasing ocean surface temperatures induce frequent coral mass bleaching events-the breakdown of the nutritional photo-symbiosis with intracellular algae (genus: Symbiodinium ). Here, we report that Stylophora pistillata from a highly diverse reef in the Gulf of Aqaba showed no signs of bleaching despite spending 1.5 months at 1-2°C above their long-term summer maximum (amounting to 11 degree heating weeks) and a seawater pH of 7.8. Instead, their symbiotic dinoflagellates exhibited improved photochemistry, higher pigmentation and a doubling in net oxygen production, leading to a 51% increase in primary productivity. Nanoscale secondary ion mass spectrometry imaging revealed subtle cellular-level shifts in carbon and nitrogen metabolism under elevated temperatures, but overall host and symbiont biomass proxies were not significantly affected. Now living well below their thermal threshold in the Gulf of Aqaba, these corals have been evolutionarily selected for heat tolerance during their migration through the warm Southern Red Sea after the last ice age. This may allow them to withstand future warming for a longer period of time, provided that successful environmental conservation measures are enacted across national boundaries in the region.

Drought and its effect on mental health--how GPs can help.

PubMed

Sartore, Gina-Maree; Kelly, Brian; Stain, Helen J

2007-12-01

Drought has been a major stressor affecting rural New South Wales communities since late 2001. While much is known about the effects on mental health of acute natural disasters, there is less research available on the effect to communities of chronic natural disasters. Of great concern for Australian rural communities is that independent of drought, the rate of suicide for some groups is higher in rural than urban communities, while access to mental health services is less. This article explores how general practitioners can identify and respond to the drought related mental health needs of farming residents. Limited availability of mental health services to rural communities increases reliance on GPs for mental health care. Residents of farming communities report experiencing substantial distress in relation to the drought. The local GP is a key source of consultation, advice and treatment. Early intervention is a critical task in improving the mental health of rural communities. Early intervention provided by GPs will be enhanced through: working closely with other community agencies to promote early effective intervention for mental health problems, improve access to advice and initial consultation, and facilitate urgent consultation when needed; increasing access to services for farmers and responding promptly to needs; and utilising the support of rural organisational workers.

Management and Outcomes Among Chinese Hospitalized Patients With Established Cardiovascular Disease or Multiple Risk Factors.

PubMed

Yang, Jingang; Yang, Yuejin; Gu, Hongqiu; Li, Wei; Hu, Dayi

2016-02-01

We assessed the management and outcomes among hospitalized patients with coronary artery disease (CAD), stroke, peripheral artery disease (PAD), or with multiple (≥ 2) cardiovascular (CV) risk factors (multiple risk factors [MRFs]). We retrospectively studied 3732 hospitalized patients of either CV disease or ≥ 2 risk factors for atherothrombosis from October 2004 to January 2005. Outcomes included CV death, myocardial infarction (MI), stroke, and hospitalization for atherothrombotic events. About one-third had disease involving ≥ 1 vascular bed. Medication was more intense in patients with CAD than in others. The lowest use of statins and antiplatelet treatment was in the PAD-only group. Patients with PAD experienced a higher CV mortality (5.1%) than the patients with CAD (3.73%) or stroke (4.1%), P < .001. Cardiovascular death ranged from 1.2% for patients with MRFs, 2.8% for patients with 1-bed disease, 4.7% for patients with 2-bed disease to 6.4% for patients with 3-bed disease (P for trend <.001). For hospitalized patients with established atherosclerotic arterial disease, a substantial increase in CV event rates occurs with increasing numbers of affected arterial beds. Patients with PAD were at an especially high risk. © The Author(s) 2015.

Measuring the impact of air pollution on respiratory infection risk in China.

PubMed

Tang, Sanyi; Yan, Qinling; Shi, Wei; Wang, Xia; Sun, Xiaodan; Yu, Pengbo; Wu, Jianhong; Xiao, Yanni

2018-01-01

China is now experiencing major public health challenges caused by air pollution. Few studies have quantified the dynamics of air pollution and its impact on the risk of respiratory infection. We conducted an integrated data analysis to quantify the association among air quality index (AQI), meteorological variables and respiratory infection risk in Shaanxi province of China in the period of November 15th, 2010 to November 14th, 2016. Our analysis illustrated a statistically significantly positive correlation between the number of influenza-like illness (ILI) cases and AQI, and the respiratory infection risk has increased progressively with increased AQI with a time lag of 0-3 days. We also developed mathematical models for the AQI trend and respiratory infection dynamics, incorporating AQI-dependent incidence and AQI-based behaviour change interventions. Our combined data and modelling analysis estimated the basic reproduction number for the respiratory infection during the studying period to be 2.4076, higher than the basic reproduction number of the 2009 pandemic influenza in the same province. Our modelling-based simulations concluded that, in terms of respiratory infection risk reduction, the persistent control of emission in the China's blue-sky programme is much more effective than substantial social-economic interventions implemented only during the smog days. Copyright © 2017 Elsevier Ltd. All rights reserved.

USGS integrated drought science

USGS Publications Warehouse

Ostroff, Andrea C.; Muhlfeld, Clint C.; Lambert, Patrick M.; Booth, Nathaniel L.; Carter, Shawn L.; Stoker, Jason M.; Focazio, Michael J.

2017-06-05

Project Need and OverviewDrought poses a serious threat to the resilience of human communities and ecosystems in the United States (Easterling and others, 2000). Over the past several years, many regions have experienced extreme drought conditions, fueled by prolonged periods of reduced precipitation and exceptionally warm temperatures. Extreme drought has far-reaching impacts on water supplies, ecosystems, agricultural production, critical infrastructure, energy costs, human health, and local economies (Milly and others, 2005; Wihlite, 2005; Vörösmarty and others, 2010; Choat and others, 2012; Ledger and others, 2013). As global temperatures continue to increase, the frequency, severity, extent, and duration of droughts are expected to increase across North America, affecting both humans and natural ecosystems (Parry and others, 2007).The U.S. Geological Survey (USGS) has a long, proven history of delivering science and tools to help decision-makers manage and mitigate effects of drought. That said, there is substantial capacity for improved integration and coordination in the ways that the USGS provides drought science. A USGS Drought Team was formed in August 2016 to work across USGS Mission Areas to identify current USGS drought-related research and core capabilities. This information has been used to initiate the development of an integrated science effort that will bring the full USGS capacity to bear on this national crisis.

The Long-Term Health Implications of Marital Disruption: Divorce, Work Limits, and Social Security Disability Benefits Among Men.

PubMed

Couch, Kenneth A; Tamborini, Christopher R; Reznik, Gayle L

2015-10-01

We provide new evidence on the long-term impact of divorce on work disability among U.S. men. Using data from the 2004 Survey of Income and Program Participation linked to U.S. Social Security Administration records, we assess the relationship between divorce and subsequent self-reports of work limitations and the receipt of federal disability benefits. The examination of self-reports and administrative records of medically qualified benefits provides dual confirmation of key relationships. We compare men who experienced a marital dissolution between 1975 and 1984 with continuously married men for 20 years following divorce using fixed-effects and propensity score matching models, and choose a sample to help control for selection into divorce. On average, we find that divorce is not associated with an increased probability of self-reported work limitations or receipt of disability benefits over the long run. However, among those who do not remarry, we do find that divorce increases men's long-term probability of both self-reported work limitations and federal disability benefit receipt. Lack of marital resources may drive this relationship. Alternative estimates that do not control for selection into divorce demonstrate that selection bias can substantially alter findings regarding the relationship between marital status changes and subsequent health.

Blending local scale information for developing agricultural resilience in Ethiopia

USGS Publications Warehouse

Funk, Christopher C.; Husak, Gregory; Mahiny, A.S; Eilerts, Gary; Rowland, James

2013-01-01

This brief article looks at the intersection of climate, land cover/land use, and population trends in the world's most food insecure country, Ethiopia. As a result of warming in the Indian and Western Pacific oceans, Ethiopia has experienced substantial drying over the past 20 years. We intersect the spatial pattern of this drying with high resolution climatologies, maps of agricultural expansion, population data, and socioeconomic livelihoods information to suggest that the coincidence of drying and agricultural expansion in south-central Ethiopia is likely adversely affecting a densely populated region with high levels of poverty and low wage levels.

High voltage bushing having weathershed and surrounding stress relief collar

DOEpatents

Cookson, Alan H.

1981-01-01

A high voltage electric bushing comprises a hollow elongated dielectric weathershed which encloses a high voltage conductor. A collar formed of high voltage dielectric material is positioned over the weathershed and is bonded thereto by an interface material which precludes moisture-like contaminants from entering between the bonded portions. The collar is substantially thicker than the adjacent weathershed which it surrounds, providing relief of the electric stresses which would otherwise appear on the outer surface of the weathershed. The collar may include a conductive ring or capacitive foil to further relieve electric stresses experienced by the bushing.

Pegasus air-launched space booster

NASA Astrophysics Data System (ADS)

Lindberg, Robert E.; Mosier, Marty R.

The launching of small satellites with the mother- aircraft-launched Pegasus booster yields substantial cost improvements over ground launching and enhances operational flexibility, since it allows launches to be conducted into any orbital inclination. The Pegasus launch vehicle is a three-stage solid-rocket-propelled system with delta-winged first stage. The major components of airborne support equipment, located on the mother aircraft, encompass a launch panel operator console, an electronic pallet, and a pylon adapter. Alternatives to the currently employed B-52 launch platform aircraft have been identified for future use. Attention is given to the dynamic, thermal, and acoustic environments experienced by the payload.

How anxiety induces verbal hallucinations

PubMed Central

Ratcliffe, Matthew; Wilkinson, Sam

2016-01-01

Verbal hallucinations are often associated with pronounced feelings of anxiety, and it has also been suggested that anxiety somehow triggers them. In this paper, we offer a phenomenological or ‘personal-level’ account of how it does so. We show how anxious anticipation of one’s own thought contents can generate an experience of their being ‘alien’. It does so by making an experience of thinking more like one of perceiving, resulting in an unfamiliar kind of intentional state. This accounts for a substantial subset of verbal hallucinations, which are experienced as falling within one’s psychological boundaries and lacking in auditory qualities. PMID:26683229

Establishing and Maintaining a Satellite Campus Connected by Synchronous Video Conferencing

PubMed Central

Fox, Brent I.; McDonough, Sharon L.; McConatha, Barry J.; Marlowe, Karen F.

2011-01-01

Pharmacy education has experienced substantial growth in the number of new schools and existing schools establishing satellite campuses. Several models have previously been used to connect primary and satellite campuses. We describe the Auburn University Harrison School of Pharmacy's (AUHSOP's) experiences using synchronous video conferencing between the Auburn University campus in Auburn and a satellite campus in Mobile, Alabama. We focus on the technology considerations related to planning, construction, implementation, and continued use of the various resources that support our program. Students’ perceptions of their experiences related to technology also are described. PMID:21829265

Migration, self-selection and earnings in Philippine rural communities.

PubMed

Lanzona, L A

1998-06-01

"Estimated returns to schooling investments can be misleading if migration causes significant shifts in population distribution across time. Data gathered in rural Philippine communities show that the more educated and experienced individuals are more likely to outmigrate, causing a sample selection bias in the estimation of wage equations. The observed wages were then lower than the conditional population mean of an entire cohort residing originally in the area. Controlling for self-selection, the wage returns to schooling and experience were higher, Finally, the sample selectivity variable accounts substantially for the difference in the wages of men and women." excerpt

Perceived and real barriers for men entering nursing: implications for gender diversity.

PubMed

Roth, Jay E; Coleman, Christopher Lance

2008-01-01

The objective of this literature review is to describe the perceived or real barriers to men seeking a career in nursing, and to suggest strategies for ameliorating barriers. A literature search exploring barriers existing for men pursuing nursing was conducted. Although the literature underscored the structure of nursing has changed substantially over the last fifty years, these changes have not always provoked a change in the public's perception of nursing. Barriers for men entering nursing still exist. Implications for gender diversity in nursing are discussed. Strategies for decreasing barriers experienced by males entering nursing are warranted.

Assessment of family history of substance abuse for preventive interventions with patients experiencing chronic pain: A quality improvement project.

PubMed

Pestka, Elizabeth; Nash, Virginia; Evans, Michele; Cronin, Joan; Bee, Susan; King, Susan; Osborn, Kristine; Gehin, Jessica; Weis, Karen; Loukianova, Larissa

2016-04-01

This quality improvement project demonstrates that RN Care Managers, in a chronic pain programme, can assess for a family history of substance abuse in 5-10 min. Information informs treatment based on specific high risk criteria. Benefits include heightened awareness of the genetic and environmental risks associated with a family history of substance abuse, an opportunity to participate in motivational interventions to prevent or minimize consequences of substance use disorders, and likely substantial overall health-care cost savings. © 2015 John Wiley & Sons Australia, Ltd.

Memories of Vietnam: post-traumatic stress disorders in Australian veterans.

PubMed

Tennant, C; Streimer, J H; Temperly, H

1990-03-01

We compared a random sample of Australian Vietnam veteran inpatients suffering from Post Traumatic Stress Disorder (PTSD) (N = 13) with veteran inpatients with other neurotic diagnoses. Those with PTSD had experienced substantially higher levels of combat stress, were more likely to have manifested conduct disorder in childhood, and had poorer work adjustment. Only three had been diagnosed as having traumatic or war neuroses by their original treating psychiatrist in the Veterans Affairs Department. Post traumatic stress disorder (or war neurosis) has possibly been under-diagnosed by treating psychiatrists in the Veterans Affairs Department, especially in the pre-DSM-III era.

Low Level Light Could Work on Skin Inflammatory Disease: A Case Report on Refractory Acrodermatitis Continua

PubMed Central

Choi, Mira; Na, Se Young; Cho, Soyun

2011-01-01

Low level laser or light treatment on the various clinical condition is getting considerable attention now. However, there has been no report about the clinical effect of low level polarized polychromatic noncoherent light (LPPL) on the inflammatory skin disease. We experienced a case of acrodermatitis continua in a pregnant woman refractory to any conventional treatment including the most potent topical steroid. She was successfully treated with LPPL. LPPL could be a possible treatment modality producing substantial clinical result in inflammatory skin condition without any side-effect. PMID:21394319

The high-energy-density counterpropagating shear experiment and turbulent self-heating

DOE PAGES

Doss, F. W.; Fincke, J. R.; Loomis, E. N.; ...

2013-12-06

The counterpropagating shear experiment has previously demonstrated the ability to create regions of shockdriven shear, balanced symmetrically in pressure and experiencing minimal net drift. This allows for the creation of a high-Mach-number high-energy-density shear environment. New data from the counterpropagating shear campaign is presented, and both hydrocode modeling and theoretical analysis in the context of a Reynolds-averaged-Navier-Stokes model suggest turbulent dissipation of energy from the supersonic flow bounding the layer is a significant driver in its expansion. A theoretical minimum shear flow Mach number threshold is suggested for substantial thermal-turbulence coupling.

Elevated depressive symptoms among caregiving grandparents.

PubMed

Blustein, Jan; Chan, Sewin; Guanais, Frederico C

2004-12-01

To determine whether caregiving grandparents are at an increased risk for depressive symptoms. National sample (n=10,293) of grandparents aged 53-63 years in 1994, and their spouse/partners, who took part in the Health and Retirement Study (HRS). Grandparents were surveyed in 1994 and resurveyed every two years thereafter, through 2000. Over that period, 977 had a grandchild move in or out of their home. These grandparents served as their own controls to assess the impact of having a grandchild in the home. Data Extraction. Depressive symptoms were measured using an abbreviated form of the Center for Epidemiologic Studies-Depression (CES-D) scale, scored 1-8, with a score > or =4 associated with depression "caseness". At the time of the 1994 interview, 8.2 percent of grandparents had a grandchild in their home. However, there was substantial variation across demographic groups (e.g., 29.4 percent of single nonwhite grandmothers, but only 2.0 percent of single white grandfathers had a grandchild in residence). The impact of having a grandchild in the home varied by grandparent demographic group, with single grandparents and those without coresident adult children experiencing the greatest probability of elevation in depressive symptoms when a grandchild was in residence. For example, single nonwhite grandmothers experienced an 8 percentage point increase in the probability of having a CES-D score > or =4 when a grandchild was in their home, compared to when a grandchild was not in their home, controlling for changes in health care, income, and household composition over time (95 percent CI=0.1 to 15.0 percentage points). Grandparents have a greater probability of elevated depressive symptoms when a grandchild is in their home, versus when a grandchild is not in their home. Single women of color bear a disproportionate burden of the depression associated with caring for grandchildren. Since an increasing number of grandparents function as a de facto safety net keeping their grandchildren out of formal foster care, identifying strategies to support the health and well-being of caregiving grandparents is an emerging priority.

Defining the gap: a systematic review of the difference in rates of diabetes-related foot complications in Aboriginal and Torres Strait Islander Australians and non-Indigenous Australians.

PubMed

West, Matthew; Chuter, Vivienne; Munteanu, Shannon; Hawke, Fiona

2017-01-01

The Aboriginal and Torres Strait Islander community has an increased risk of developing chronic illnesses including diabetes. Among people with diabetes, foot complications are common and make a significant contribution to the morbidity and mortality associated with this disease. The aim of this review was to systematically evaluate the literature comparing the rates of diabetes related foot complications in Aboriginal and Torres Strait Islander Australians to non-Indigenous Australians. MEDLINE, EMBASE, The Cochrane Library; PUBMED and CINAHL were searched from inception until August 2016. Inclusion criteria were: published cross-sectional or longitudinal studies reporting the prevalence of diabetes related foot complications in both a cohort of Aboriginal and Torres Strait Islander Australians and a cohort of one other Australian population of any age with diabetes. Risk of bias was assessed using the STROBE tool. Eleven studies including a total of 157,892 participants were included. Studies were set in Queensland, the Northern Territory and Western Australia, primarily in rural and remote areas. Aboriginal and Torres Strait Islander Australians experienced substantially more diabetes related foot complications with the mean age up to 14 years younger than non-Indigenous Australians. Aboriginality was associated with increased risk of peripheral neuropathy, foot ulceration and amputation. In several studies, Aboriginal and Torres Strait Islander Australians accounted for the vast majority of diabetes related foot complications (up to 91%) while comprising only a small proportion of the regional population. Reporting quality as assessed with the STROBE tool showed underreporting of: methods, sample description and potential sources of bias. There are no data available for some Australian states and for specific types of diabetes related foot complications. Aboriginal and Torres Strait Islander Australians have a 3-6 fold increased likelihood of experiencing a diabetes related foot complication compared to non-Indigenous Australians. Evidence-based, culturally appropriate screening and intervention programs and improved access to effective health care services are required to prevent a widening of the gap in diabetes related foot complications between Aboriginal and Torres Strait Islander and non-Indigenous Australians.

Fire treatment effects on vegetation structure, fuels, and potential fire severity in western U.S. forests

USGS Publications Warehouse

Stephens, S.L.; Moghaddas, J.J.; Edminster, C.; Fiedler, C.E.; Haase, S.; Harrington, M.; Keeley, J.E.; Knapp, E.E.; Mciver, J.D.; Metlen, K.; Skinner, C.N.; Youngblood, A.

2009-01-01

Abstract. Forest structure and species composition in many western U.S. coniferous forests have been altered through fire exclusion, past and ongoing harvesting practices, and livestock grazing over the 20th century. The effects of these activities have been most pronounced in seasonally dry, low and mid-elevation coniferous forests that once experienced frequent, low to moderate intensity, fire regimes. In this paper, we report the effects of Fire and Fire Surrogate (FFS) forest stand treatments on fuel load profiles, potential fire behavior, and fire severity under three weather scenarios from six western U.S. FFS sites. This replicated, multisite experiment provides a framework for drawing broad generalizations about the effectiveness of prescribed fire and mechanical treatments on surface fuel loads, forest structure, and potential fire severity. Mechanical treatments without fire resulted in combined 1-, 10-, and 100-hour surface fuel loads that were significantly greater than controls at three of five FFS sites. Canopy cover was significantly lower than controls at three of five FFS sites with mechanical-only treatments and at all five FFS sites with the mechanical plus burning treatment; fire-only treatments reduced canopy cover at only one site. For the combined treatment of mechanical plus fire, all five FFS sites with this treatment had a substantially lower likelihood of passive crown fire as indicated by the very high torching indices. FFS sites that experienced significant increases in 1-, 10-, and 100-hour combined surface fuel loads utilized harvest systems that left all activity fuels within experimental units. When mechanical treatments were followed by prescribed burning or pile burning, they were the most effective treatment for reducing crown fire potential and predicted tree mortality because of low surface fuel loads and increased vertical and horizontal canopy separation. Results indicate that mechanical plus fire, fire-only, and mechanical-only treatments using whole-tree harvest systems were all effective at reducing potential fire severity under severe fire weather conditions. Retaining the largest trees within stands also increased fire resistance. ?? 2009 by the Ecological Society of America.

Accuracy, reliability, and timing of visual evaluations of decay in fresh-cut lettuce

PubMed Central

Hayes, Ryan J.

2018-01-01

Visual assessments are used for evaluating the quality of food products, such as fresh-cut lettuce packaged in bags with modified atmosphere. We have compared the accuracy and the reliability of visual evaluations of decay on fresh-cut lettuce performed with experienced and inexperienced raters. In addition, we have analyzed decay data from over 4.5 thousand bags to determine the optimum timing for evaluations to detect differences among accessions. Lin’s concordance coefficient (ρc) that takes into consideration both the closeness of the data and the conformance to the identity line showed high repeatability (intra-rater reliability, ρc = 0.97), reproducibility (inter-rater reliability, ρc = 0.92), and accuracy (ρc = 0.96) for experienced raters. Inexperienced raters did not perform as well and their ratings showed decreased repeatability (ρc = 0.93), but even larger reduction in reproducibility (ρc = 0.80) and accuracy (ρc = 0.90). We have detected that 5.3% of ratings were outside of the 95% limits of agreement. These under- or overestimates were predominantly found for bags with intermediate levels of decay, which corresponds to the middle of the rating scale. This occurs because intermediate amounts of decay are more difficult to discriminate than extremes. The frequencies of aberrant ratings for experienced raters ranged from 0.6% to 4.4% (mean = 2.1%), for inexperienced raters the frequencies were substantially higher, ranging from 6.1% to 15.6% (mean = 9.4%). Therefore, we recommend that new raters receive training that includes practical examples in this range of decay, use of standard area diagrams, and continuing interaction with experienced raters (consultation during actual rating). Very high agreement among experienced raters indicate that visual ratings can be successfully used for evaluations of decay, until a more objective, rapid, and affordable method is developed. We recommend evaluating samples at multiple time points until 42 days after processing (about 80% decay on average) and then combining these individual ratings into the area under the decay progress stairs (AUDePS) score. Applying this approach, experienced evaluators can accurately detect difference among lettuce accessions and identify lettuce cultivars with reduced decay. PMID:29664945

Trajectories and Risk Factors for Post-Traumatic Stress Symptoms following Pediatric Concussion.

PubMed

Truss, Katherine; Godfrey, Celia; Takagi, Michael; Babl, Franz E; Bressan, Silvia; Hearps, Stephen; Clarke, Cathriona; Dunne, Kevin; Anderson, Vicki

2017-07-15

A substantial minority of children experience post-traumatic stress symptoms (PTSS) following injury. Research indicates variation in the trajectory of PTSS following pediatric injury, but investigation of PTSS following concussion has assumed homogeneity. This study aimed to identify differential trajectories of PTSS following pediatric concussion and to investigate risk factors, including acute post-concussive symptoms (PCS), associated with these trajectories. A total of 120 children ages 8-18 years reported PTSS for 3 months following concussion diagnosis using the Child PTSD Symptom Scale, with a score of 16 or above indicating probable post-traumatic stress disorder diagnosis. Age, gender, injury mechanism, loss of consciousness, previous concussions, prior hospitalization, prior diagnosis of depression or anxiety, and acute PCS were assessed as risk factors. Data were analyzed using group-based trajectory modeling. Results revealed 16% of children had clinically significant PTSS 2 weeks post-concussion, declining to 10% at 1 month and 6% at 3 months post-injury. Group-based trajectory modeling identified three trajectories of PTSS post-concussion: "resilient" (70%); "recovering" (25%), in which children experienced elevated acute symptoms that declined over time; and "chronic symptomatology" (5%). Due to small size, the chronic group should be interpreted with caution. Higher acute PCS and prior diagnosis of depression or anxiety both significantly increased predicted probability of recovering trajectory group membership. These findings establish that most children are resilient to PTSS following concussion, but that PTSS do occur acutely in a substantial minority of children. The study indicates mental health factors, particularly PTSS, depression, and anxiety, should be considered integral to models of concussion management and treatment.

Pain in IBD Patients: Very Frequent and Frequently Insufficiently Taken into Account

PubMed Central

Ak, Melike; Müller-Mottet, Séverine; Scharl, Sylvie; Biedermann, Luc; Fournier, Nicolas; Frei, Pascal; Pittet, Valerie; Scharl, Michael; Fried, Michael

2016-01-01

Background Pain is a common symptom related to inflammatory bowel disease (IBD). In addition to abdominal pain, pain can also be an extraintestinal manifestation of IBD. Pain treatment is challenging and a substantial part of IBD patients are treated with opioids. Therefore, a better knowledge on pain symptoms is crucial for a better therapeutic approach to this clinical problem. Methods Patients of the Swiss IBD Cohort Study (SIBDCS) (n = 2152) received a questionnaire regarding pain intensity, pain localization and impact of pain on daily life and social activities. Furthermore, the questionnaire investigated the use of pain-specific medication. Results A vast majority of patients (71%) experienced pain during the disease course. For a substantial part of patients (49% in UC and 55% in CD) pain is a longstanding problem (>5 years). Pain in UC was of shorter duration compared to CD (p < 0.01). Abdominal pain (59.5%) and back pain (38.3%) were the main pain localizations. 67% of patients took pain medication; 24% received no pain treatment. The general quality of life was significantly lower in patients suffering of pain compared to those without pain (38 vs. 77; (-100 very bad; 100 very good) p<0.0001). Conclusions Prevalence of pain is high in patients of the SIBDCS. It is a longstanding problem for the majority of the patients affected. Pain was found to be undertreated in the SIBDCS and was significantly associated with health-related quality of life. Thus, an increased awareness is mandatory to address this frequent complication in the course of IBD. PMID:27332879

Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice

PubMed Central

Moore, R A; Moore, O A; Derry, S; Peloso, P M; Gammaitoni, A R; Wang, H

2010-01-01

Background: Population mean changes from clinical trials are difficult to apply to individuals in clinical practice. Responder analysis may be better, but needs validating for level of response and treatment duration. Methods: The numbers of patients with pain relief over baseline (⩾15%, ⩾30%, ⩾50%, ⩾70%) at 2, 4, 8 and 12 weeks of treatment were obtained using the WOMAC 100 mm visual analogue pain subscale score for each treatment group in seven randomised placebo-controlled trials of etoricoxib in osteoarthritis lasting ⩾6 weeks. Dropouts were assigned 0% improvement from baseline from then on. The numbers needed to treat (NNTs) were calculated at each level of response and time point. Results: 3554 patients were treated with placebo, etoricoxib 30 mg and 60 mg, celecoxib 200 mg, naproxen 1000 mg or ibuprofen 2400 mg daily. Response rates fell with increasing pain relief: 60–80% experienced minimally important pain relief (⩾15%), 50–60% moderate pain relief (⩾30%), 40–50% substantial pain relief (⩾50%) and 20–30% extensive pain relief (⩾70%). NNTs for etoricoxib, celecoxib and naproxen were stable over 2–12 weeks. Ibuprofen showed lessening of effectiveness with time. Conclusion: Responder rates and NNTs are reproducible for different levels of response over 12 weeks and have relevance for clinical practice at the individual patient level. An average 10 mm improvement in pain equates to almost one in two patients having substantial benefit. PMID:19364730

Spatial and temporal changes in the Barents Sea pelagic compartment during the recent warming

NASA Astrophysics Data System (ADS)

Eriksen, Elena; Skjoldal, Hein Rune; Gjøsæter, Harald; Primicerio, Raul

2017-02-01

The Barents Sea has experienced substantial warming over the last few decades with expansion of relatively warm Atlantic water and reduction in sea ice. Based on a review of relevant literature and additional analyses, we report changes in the pelagic compartment associated with this warming using data from autumn surveys (acoustic capelin, 0-group fish, and ecosystem surveys). We estimated biomass for 25 components of the pelagic community, including macroplankton, 0-group fish, and juvenile and adult pelagic fish, were examined for spatial and temporal variation over the period 1993-2013. The estimated total biomass of the investigated pelagic compartment, not including mesozooplankton, ranged between about 6 and 30 million tonnes wet weight with an average of 17 million tonnes over the 21-years period. Krill was the dominant biomass component (63%), whereas pelagic fish (capelin, polar cod and herring) made up 26% and 0-group fish 11% of the biomass on average. The spatial distribution of biomass showed a broad-scale pattern reflecting differences in distribution of the main pelagic fishes (capelin in the north, polar cod in the east, and herring in the south) and transport of krill and 0-group fish with the Atlantic water flowing into the southern Barents Sea. Dividing the Barents Sea into six regions, the highest average biomass values were found in the Southwestern and South-Central subareas (about 4 million tonnes in each), with krill as the main component. Biomass was also high in the North-Central subarea (about 3 million tonnes) where capelin was the major contributor. The total estimated biomass of the pelagic compartment remained relatively stable during each of two main periods (before and after 2004), but increased by a factor of two from around 11 million tonnes in the first to around 23 million tonnes in the last period. The pronounced increase reflected the warming between the relatively cold 1990s and the warmer 2000s and was driven mainly by an increase in krill due presumably to increased advection. Variable recruitment of fish had a strong influence on the variation in pelagic biomass, first as 0-group fish (including demersal species such as cod and haddock) and subsequently over the next years manifested as strong or weak year classes of dominant pelagic species. Associated with the warming there was also a northern or eastern extension of the distribution of several components although the broad-scale geographical pattern of biomass distribution remained similar between the first and the last parts of the investigated period. The capelin stock, a dominant species with a substantial contribution to total biomass, experienced two collapses followed by recoveries in the 1990s and 2000s. The apparent stability in total biomass in each of the two periods (before and after 2004) reflected compensating and dampening mechanisms. In the first period, krill showed an inverse relationship with capelin, increasing when the capelin stock was low. In the second period, other fishes including juvenile herring, polar cod and blue whiting increased to fill the 'void' of the low capelin stock. The syntheses reported here provides a basis for modelling some of the key players and dominating processes and drivers of change in the ecosystem.

Ethnic Diversity, Inter-group Attitudes and Countervailing Pathways of Positive and Negative Inter-group Contact: An Analysis Across Workplaces and Neighbourhoods.

PubMed

Laurence, James; Schmid, Katharina; Hewstone, Miles

2018-01-01

This study advances the current literature investigating the relationship between contextual out-group exposure, inter-group attitudes and the role of inter-group contact. Firstly, it introduces the concept of contact-valence into this relationship; that is, whether contact is experienced positively or negatively. Secondly, it presents a comparative analysis of how processes of out-group exposure and frequency of (valenced) contact affect prejudice across both neighbourhoods and workplaces. Applying path analysis modelling to a nationally-representative sample of white British individuals in England, we demonstrate, across both contexts, that increasing out-group exposure is associated with higher rates of both positively- and negatively-valenced contact. This results in exposure exhibiting both positive and negative indirect associations with prejudice via more frequent inter-group mixing. These countervailing contact-pathways help explain how out-group exposure is associated with inter-group attitudes. In neighbourhoods, increasing numbers of individuals experiencing positive-contact suppress an otherwise negative effect of neighbourhood diversity (driven partly by increasing numbers of individuals reporting negative contact). Across workplaces the effect differs such that increasing numbers of individuals experiencing negative-contact suppress an otherwise positive effect of workplace diversity (driven largely by increasing numbers of individuals experiencing positive contact).

Reliability of pelvic floor measurements on three- and four-dimensional ultrasound during and after first pregnancy: implications for training.

PubMed

van Veelen, G A; Schweitzer, K J; van der Vaart, C H

2013-11-01

To evaluate the reliability of measurements of the levator hiatus and levator-urethra gap (LUG) using three/four-dimensional (3D/4D) transperineal ultrasound in women during their first pregnancy and 6 months postpartum, and to assess the learning process for these measurements. An inexperienced observer was taught to perform measurements of the levator hiatus and LUG by an experienced observer. After training, 3D/4D ultrasound volume datasets of 40 women in the first trimester were analyzed by these two observers. Another training session then took place and both observers repeated the analyses of the same volume datasets. Finally, analyses of 40 volume datasets of the women 6 months postpartum were performed by both observers. Intra- and interobserver reliability were determined by intraclass correlation coefficients (ICC) with 95% CIs. For levator hiatal measurements, in the women during their first pregnancy the interobserver reliability was substantial to almost perfect after both the first and second training session (ICC, 0.62-0.83 and 0.71-0.89, respectively, for anteroposterior diameter, transverse diameter and area at rest, on contraction and on Valsalva) and the intraobserver reliability was substantial to almost perfect for both observers. For these measurements performed once the women had delivered, interobserver reliability was moderate to almost perfect. For LUG measurements performed during pregnancy, interobserver reliability was slight to moderate after the first training session (ICC, 0.14-0.54), but improved after the second training session (ICC, 0.38-0.71), and intraobserver reliability was moderate to substantial for the experienced observer and slight to moderate for the inexperienced observer. For these measurements performed when the women had delivered, interobserver reliability was fair to moderate. The levator hiatus and LUG can be measured reliably using 3D/4D ultrasound in primigravid and primiparous women. The technique to measure dimensions of the levator hiatus requires limited teaching, but LUG measurements are more difficult and require more extensive training. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd.

Financial and employment impacts of serious injury: a qualitative study.

PubMed

Gabbe, Belinda J; Sleney, Jude S; Gosling, Cameron M; Wilson, Krystle; Sutherland, Ann; Hart, Melissa; Watterson, Dina; Christie, Nicola

2014-09-01

To explore the financial and employment impacts following serious injury. Semi-structured telephone administered qualitative interviews with purposive sampling and thematic qualitative analysis. 118 patients (18-81 years) registered by the Victorian State Trauma Registry or Victorian Orthopaedic Trauma Outcomes Registry 12-24 months post-injury. Key findings of the study were that although out-of-pocket treatment costs were generally low, financial hardship was prevalent after hospitalisation for serious injury, and was predominantly experienced by working age patients due to prolonged absences from paid employment. Where participants were financially pressured prior to injury, injury further exacerbated these financial concerns. Reliance on savings and loans and the need to budget carefully to limit financial burden were discussed. Financial implications of loss of income were generally less for those covered by compensation schemes, with non-compensable participants requiring welfare payments due to an inability to earn an income. Most participants reported that the injury had a negative impact on work. Loss of earnings payments from injury compensation schemes and income protection policies, supportive employers, and return to work programs were perceived as key factors in reducing the financial burden of injured participants. Employer-related barriers to return to work included the employer not listening to the needs of the injured participant, not understanding their physical limitations, and placing unrealistic expectations on the injured person. While the financial benefits of compensation schemes were acknowledged, issues accessing entitlements and delays in receiving benefits were commonly reported by participants, suggesting that improvements in scheme processes could have substantial benefits for injured patients. Seriously injured patients commonly experienced substantial financial and work-related impacts of injury. Participants of working age who were unemployed prior to injury, did not have extensive leave accrual at their pre-injury employment, and those not covered by injury compensation schemes or income protection insurance clearly represent participants "at risk" for substantial financial hardship post-injury. Early identification of these patients, and improved provision of information about financial support services, budgeting and work retraining could assist in alleviating financial stress after injury. Copyright © 2014 Elsevier Ltd. All rights reserved.

Child Protection Investigations in Out-of-Home Care: Perpetrators, Victims, and Contexts.

PubMed

Font, Sarah A

2015-11-01

Keeping children safe in out-of-home care requires an understanding of the contexts under which maltreatment occurs. This study examines how maltreatment investigations differ across four settings (nonrelative foster, informal kinship, formal kinship, and congregate care). I focus on four elements of maltreatment: the perpetrator's role (e.g., out-of-home caregiver and peer), maltreatment type, probability of substantiation, and victim characteristics. I use statewide Wisconsin administrative data in years 2005-2012, which has an analytic sample of over 96,000 placements. Data are analyzed using descriptive statistics and multi-level logistic regression. Alleged maltreatment is not uncommon in out-of-home care-the total investigation rate ranged from 5% (congregate care) to 15% (informal kinship care). Four percent of all placements were investigated for maltreatment by an out-of-home caregiver, of which 9% were substantiated. Maltreatment by peers (siblings or other foster children) was investigated in 1% of all placements, of which 20% were substantiated. Neglect was the most commonly alleged maltreatment type in informal kinship care, whereas physical abuse was most commonly alleged in all other placement types. Children who were female, Black, or between ages 6 and 10 experienced heightened risk of maltreatment in out-of-home care. © The Author(s) 2015.

Child Protection Investigations in Out-of-Home Care: Perpetrators, Victims, and Contexts

PubMed Central

Font, Sarah A.

2015-01-01

Keeping children safe in out-of-home care requires an understanding of the contexts under which maltreatment occurs. This study examines how maltreatment investigations differ across four settings (nonrelative foster, informal kinship, formal kinship, and congregate care). I focus on four elements of maltreatment: the perpetrator’s role (e.g., out-of-home caregiver and peer), maltreatment type, probability of substantiation, and victim characteristics. I use statewide Wisconsin administrative data in years 2005–2012, which has an analytic sample of over 96,000 placements. Data are analyzed using descriptive statistics and multi-level logistic regression. Alleged maltreatment is not uncommon in out-of-home care—the total investigation rate ranged from 5% (congregate care) to 15% (informal kinship care). Four percent of all placements were investigated for maltreatment by an out-of-home caregiver, of which 9% were substantiated. Maltreatment by peers (siblings or other foster children) was investigated in 1% of all placements, of which 20% were substantiated. Neglect was the most commonly alleged maltreatment type in informal kinship care, whereas physical abuse was most commonly alleged in all other placement types. Children who were female, Black, or between ages 6 and 10 experienced heightened risk of maltreatment in out-of-home care. PMID:26224743

Has the sensitivity of soybean cultivars to ozone pollution increased with time? An analysis of published dose-response data

USDA-ARS?s Scientific Manuscript database

The rising trend in concentrations of ground-level ozone (O3) – a common air pollutant and phytotoxin – currently being experienced in some world regions represents a threat to agricultural yield. Soybean (Glycine max (L.) Merr.) is an O3-sensitive crop species, and is experiencing increasing globa...

Help-Seeking Decisions of Battered Women: A Test of Learned Helplessness and Two Stress Theories.

ERIC Educational Resources Information Center

Wauchope, Barbara A.

This study tested the learned helplessness theory, stress theory, and a modified stress theory to determine the best model for predicting the probability that a woman would seek help when she experienced severe violence from a male partner. The probability was hypothesized to increase as the stress of the violence experienced increased. Data were…

Why Do Some Adolescents Encounter Everyday Events That Increase Their Civic Interest Whereas Others Do Not?

ERIC Educational Resources Information Center

Stattin, Håkan; Hussein, Oula; Özdemir, Metin; Russo, Silvia

2017-01-01

Using a longitudinal design, we asked 2 age cohorts of adolescents (15- and 18-year-olds) whether they, during the last year, had experienced events that had increased their civic interest and about details of their experiences. Based on self-determination theory, we predicted that the adolescents who reported having experienced events of this…

First and recurrent ischaemic heart disease events continue to decline in New Zealand, 2005-2015.

PubMed

Grey, Corina; Jackson, Rod; Wells, Susan; Wu, Billy; Poppe, Katrina; White, Harvey; Chan, Wing Cheuk; Kerr, Andrew J

2018-01-01

To examine recent trends in first and recurrent ischaemic heart disease (IHD) deaths and hospitalisations. Using anonymous patient-linkage of routinely collected data, all New Zealanders aged 35-84 years who experienced an International Statistical Classification of Diseases and Related Health Problems I(CD)-coded IHD hospitalisation and/or IHD death between 1 January 2005 and 31 December 2015 were identified. A 10-year look-back period was used to differentiate those experiencing first from recurrent events. Age-standardised hospitalisation and mortality rates were calculated for each calendar year and trends compared by sex and age. 160 109 people experienced at least one IHD event (259 678 hospitalisations and 35 548 deaths) over the 11-year study period, and there was a steady decline in numbers (from almost 24 000 in 2005 to just over 16 000 in 2015) and in age-standardised rates each year. With the exception of deaths in younger (35-64 years) women with prior IHD, there was a significant decline in IHD events in men and women of all ages, with and without a history of IHD. The decline in IHD mortality was greater for those experiencing a first rather than recurrent IHD event (3.8%-5.2% vs 0%-3.7% annually on average). In contrast, the decline in IHD hospitalisations was greater for those experiencing a recurrent compared with a first IHD event (5.6%-7.3% vs 3.2%-5.7% annually on average). The substantial decline in IHD hospitalisations and mortality observed in New Zealanders with and without prior IHD between 2005 and 2015 suggests that primary and secondary prevention efforts have been effective in reducing the occurrence of IHD events. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.