The neural effects of positively and negatively re-experiencing mental fatigue sensation: a magnetoencephalography study.

PubMed

Ishii, Akira; Ishizuka, Takuya; Muta, Yuki; Tanaka, Masaaki; Yamano, Emi; Watanabe, Yasuyoshi

2018-06-01

Fatigue sensation is an essential biological alarm that urges us to take rest to avoid disrupting homeostasis and thus plays an important role in maintaining well-being. However, there are situations in which the anticipation of unpleasant fatigue sensation undesirably reduces motivation for activity. The aim of this study was to examine whether thinking positively about the fatigue sensation would increase motivation to accomplish the workload. Fourteen healthy male volunteers participated in this study and performed a two-back test for 30 min to induce mental fatigue sensation. After their subjective level of fatigue had recovered to the baseline level, they re-experienced the fatigue sensation experienced in the two-back test positively, negatively, and without any modification (i.e., re-experienced the fatigue sensation as it was). The level of motivation to perform another two-back test they felt during the re-experiencing was assessed. The neural activity related to the re-experiencing was recorded using magnetoencephalography. The level of the motivation to perform another two-back test was increased by positively re-experiencing the fatigue sensation. The increase in delta band power in Brodmann area 7 was positively associated with the increase in motivation. These results show that positive thinking about fatigue sensation can enhance motivation and suggest that this enhanced motivation may have some effects on visual attention system.

Army Programmatic Environmental Assessment of the Mine Resistant Ambush Protected (MRAP) Vehicle Program

DTIC Science & Technology

2010-12-01

vehicles  with  a  blast  resistant  V‐shaped underbody designed to protect the crew from mine blasts, fragments  and direct  fire  weapons.  The CAT I vehicle...Army Programmatic Environmental  Assessment   of the  Mine  Resistant  Ambush Protected (MRAP)  Vehicle Program        December 2010...06-07-2010 to 20-11-2010 4. TITLE AND SUBTITLE Army Programmatic Environmental Assessment of the Mine Resistant Ambush Protected (MRAP) Vehicle

Ecological risks of DOE`s programmatic environmental restoration alternatives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-06-01

This report assesses the ecological risks of the Department of Energy`s (DOE) Environmental Restoration Program. The assessment is programmatic in that it is directed at evaluation of the broad programmatic alternatives outlined in the DOE Implementation Plan. It attempts to (1) characterize the ecological resources present on DOE facilities, (2) describe the occurrence and importance of ecologically significant contamination at major DOE facilities, (3) evaluate the adverse ecological impacts of habitat disturbance caused by remedial activities, and (4) determine whether one or another of the programmatic alternatives is clearly ecologically superior to the others. The assessment focuses on six representativemore » facilities: the Idaho National Engineering Laboratory (INEL); the Fernald Environmental Management Project (FEMP); the Oak Ridge Reservation (ORR), including the Oak Ridge National Laboratory (ORNL), Y-12 plant, and K-25 plant; the Rocky Flats Plant; the Hanford Reservation; and the Portsmouth Gaseous Diffusion Plant.« less

Programmatic assessment of competency-based workplace learning: when theory meets practice

PubMed Central

2013-01-01

Background In competency-based medical education emphasis has shifted towards outcomes, capabilities, and learner-centeredness. Together with a focus on sustained evidence of professional competence this calls for new methods of teaching and assessment. Recently, medical educators advocated the use of a holistic, programmatic approach towards assessment. Besides maximum facilitation of learning it should improve the validity and reliability of measurements and documentation of competence development. We explored how, in a competency-based curriculum, current theories on programmatic assessment interacted with educational practice. Methods In a development study including evaluation, we investigated the implementation of a theory-based programme of assessment. Between April 2011 and May 2012 quantitative evaluation data were collected and used to guide group interviews that explored the experiences of students and clinical supervisors with the assessment programme. We coded the transcripts and emerging topics were organised into a list of lessons learned. Results The programme mainly focuses on the integration of learning and assessment by motivating and supporting students to seek and accumulate feedback. The assessment instruments were aligned to cover predefined competencies to enable aggregation of information in a structured and meaningful way. Assessments that were designed as formative learning experiences were increasingly perceived as summative by students. Peer feedback was experienced as a valuable method for formative feedback. Social interaction and external guidance seemed to be of crucial importance to scaffold self-directed learning. Aggregating data from individual assessments into a holistic portfolio judgement required expertise and extensive training and supervision of judges. Conclusions A programme of assessment with low-stakes assessments providing simultaneously formative feedback and input for summative decisions proved not easy to implement. Careful preparation and guidance of the implementation process was crucial. Assessment for learning requires meaningful feedback with each assessment. Special attention should be paid to the quality of feedback at individual assessment moments. Comprehensive attention for faculty development and training for students is essential for the successful implementation of an assessment programme. PMID:24020944

A programmatic approach to address increasing HIV diagnoses among Hispanic/Latino MSM, 2010-2014.

PubMed

McCree, Donna Hubbard; Walker, Tanja; DiNenno, Elizabeth; Hoots, Brooke; Valverde, Eduardo; Cheryl Bañez Ocfemia, M; Heitgerd, Janet; Stallworth, JoAna; Ferro, Benny; Santana, Alberto; German, Emilio; Harris, Norma

2018-06-14

From 2010 to 2015, young (13-24 years) Hispanic/Latino gay, bisexual and other men who have sex with men (MSM) experienced the largest increase (18%) in numbers of HIV diagnoses among all racial/ethnic groups. In 2016, the Centers for Disease Control and Prevention (CDC) assembled a team of scientists and public health analysts to develop a programmatic approach for addressing the increasing HIV diagnosis among Hispanic/Latino MSM. The team used a data driven review process, i.e., comprehensive review of surveillance, epidemiologic, and programmatic data, to explore key questions from the literature on factors associated with HIV diagnoses among Hispanic/Latino MSM and to inform the approach. This paper describes key findings from the review and discusses the approach. The approach includes the following activities: increase awareness and support testing by expanding existing campaigns targeting Hispanic/Latino MSM to jurisdictions where diagnoses are increasing; strengthen existing efforts that support treatment as prevention and increase engagement in care and viral suppression among Hispanic/Latino MSM living with HIV and promote prevention, e.g., PrEP uptake and condom use, among Hispanic/Latino MSM who are at high-risk for HIV infection. Copyright © 2018. Published by Elsevier Inc.

Intrusive re-experiencing in post-traumatic stress disorder: phenomenology, theory, and therapy.

PubMed

Ehlers, Anke; Hackmann, Ann; Michael, Tanja

2004-07-01

The article describes features of trauma memories in post-traumatic stress disorder (PTSD), including characteristics of unintentional re-experiencing symptoms and intentional recall of trauma narratives. Reexperiencing symptoms are usually sensory impressions and emotional responses from the trauma that appear to lack a time perspective and a context. The vast majority of intrusive memories can be interpreted as re-experiencing of warning signals, i.e., stimuli that signalled the onset of the trauma or of moments when the meaning of the event changed for the worse. Triggers of re-experiencing symptoms include stimuli that have perceptual similarity to cues accompanying the traumatic event. Intentional recall of the trauma in PTSD may be characterised by confusion about temporal order, and difficulty in accessing important details, both of which contribute to problematic appraisals. Recall tends to be disjointed. When patients with PTSD deliberately recall the worst moments of the trauma, they often do not access other relevant (usually subsequent) information that would correct impressions/predictions made at the time. A theoretical analysis of re-experiencing symptoms and their triggers is offered, and implications for treatment are discussed. These include the need to actively incorporate updating information ("I know now ...") into the worst moments of the trauma memory, and to train patients to discriminate between the stimuli that were present during the trauma ("then") and the innocuous triggers of re-experiencing symptoms ("now").

Deployable antenna phase A study

NASA Technical Reports Server (NTRS)

Schultz, J.; Bernstein, J.; Fischer, G.; Jacobson, G.; Kadar, I.; Marshall, R.; Pflugel, G.; Valentine, J.

1979-01-01

Applications for large deployable antennas were re-examined, flight demonstration objectives were defined, the flight article (antenna) was preliminarily designed, and the flight program and ground development program, including the support equipment, were defined for a proposed space transportation system flight experiment to demonstrate a large (50 to 200 meter) deployable antenna system. Tasks described include: (1) performance requirements analysis; (2) system design and definition; (3) orbital operations analysis; and (4) programmatic analysis.

How to double the number of undergraduate physics majors

NASA Astrophysics Data System (ADS)

Kopp, Sacha

2015-03-01

Many colleges and universities around the country have a solid physics program that prepares students bound for graduate physics study. For a variety of reasons, the number of students choosing to major in physics may be small, typically <1% of the student body. When compared to other majors, this population is experiencing negligible growth. I will describe a campaign launched while at the University of Texas at Austin aimed at recruiting and retention of majors. This campaign includes actual programmatic changes in the curriculum and instruction of majors. Additionally, it includes a direct marketing campaign that attempted to change student attitudes about physics and its relation to their current major. Finally, it includes a program to reach out to local high schools and engage students in a discussion about their career choices before they apply for college. I will share some numerical and attitudinal data that suggests positive changes in the student population.

Public health agendas addressing violence against rural women - an analysis of local level health services in the State of Rio Grande do Sul, Brazil.

PubMed

da Costa, Marta Cocco; Lopes, Marta Julia Marques; Soares, Joannie dos Santos Fachinelli

2015-05-01

This study analyses health managers' perceptions of local public health agendas addressing violence against rural women in municipalities in the southern part of the State Rio Grande do Sul in Brazil. It consists of an exploratory descriptive study utilizing a qualitative approach. Municipal health managers responsible for planning actions directed at women's health and primary health care were interviewed. The analysis sought to explore elements of programmatic vulnerability related to violence in the interviewees' narratives based on the following dimensions of programmatic vulnerability: expression of commitment, transformation of commitment into action, and planning and coordination. It was found that local health agendas directed at violence against rural women do not exist. Health managers are therefore faced with the challenge of defining lines of action in accordance with the guidelines and principles of the SUS. The repercussions of this situation are expressed in fragile comprehensive services for these women and programmatic vulnerability.

The Neural Mechanisms of Re-Experiencing Mental Fatigue Sensation: A Magnetoencephalography Study

PubMed Central

Ishii, Akira; Karasuyama, Takuma; Kikuchi, Taiki; Tanaka, Masaaki; Yamano, Emi; Watanabe, Yasuyoshi

2015-01-01

There have been several studies which have tried to clarify the neural mechanisms of fatigue sensation; however fatigue sensation has multiple aspects. We hypothesized that past experience related to fatigue sensation is an important factor which contributes to future formation of fatigue sensation through the transfer to memories that are located within specific brain structures. Therefore, we aimed to investigate the neural mechanisms of fatigue sensation related to memory. In the present study, we investigated the neural activity caused by re-experiencing the fatigue sensation that had been experienced during a fatigue-inducing session. Thirteen healthy volunteers participated in fatigue and non-fatigue experiments in a crossover fashion. In the fatigue experiment, they performed a 2-back test session for 40 min to induce fatigue sensation, a rest session for 15 min to recover from fatigue, and a magnetoencephalography (MEG) session in which they were asked to re-experience the state of their body with fatigue that they had experienced in the 2-back test session. In the non-fatigue experiment, the participants performed a free session for 15 min, a rest session for 15 min, and an MEG session in which they were asked to re-experience the state of their body without fatigue that they had experienced in the free session. Spatial filtering analyses of oscillatory brain activity showed that the delta band power in the left Brodmann’s area (BA) 39, alpha band power in the right pulvinar nucleus and the left BA 40, and beta band power in the left BA 40 were lower when they re-experienced the fatigue sensation than when they re-experienced the fatigue-free sensation, indicating that these brain regions are related to re-experiencing the fatigue sensation. Our findings may help clarify the neural mechanisms underlying fatigue sensation. PMID:25826300

An Overview of the NASA FAP Hypersonics Project Airbreathing Propulsion Research

NASA Technical Reports Server (NTRS)

Auslender, A. H.; Suder, Kenneth L.; Thomas, Scott R.

2009-01-01

The propulsion research portfolio of the National Aeronautics and Space Administration Fundamental Aeronautics Program Hypersonics Project encompasses a significant number of technical tasks that are aligned to achieve mastery and intellectual stewardship of the core competencies in the hypersonic-flight regime. An overall coordinated programmatic and technical effort has been structured to advance the state-of-the-art, via both experimental and analytical efforts. A subset of the entire hypersonics propulsion research portfolio is presented in this overview paper. To this end, two programmatic research disciplines are discussed; namely, (1) the Propulsion Discipline, including three associated research elements: the X-51A partnership, the HIFiRE-2 partnership, and the Durable Combustor Rig, and (2) the Turbine-Based Combine Cycle Discipline, including three associated research elements: the Combined Cycle Engine Large Scale Inlet Mode Transition Experiment, the small-scale Inlet Mode Transition Experiment, and the High-Mach Fan Rig.

The Quest for an OCO (Orbiting Carbon Observatory) Re-Flight

NASA Technical Reports Server (NTRS)

Basilio, Ralph R.; Livermore, Thomas R.; Shen, Y. Janet; Pollock, H. Randy

2010-01-01

The objective of the OCO (Orbiting Carbon Observatory) mission was to make the first space-based measurements of atmospheric carbon dioxide with the accuracy needed to quantify sources and sinks of this important greenhouse gas. Unfortunately, the observatory was lost as a result of a launch vehicle failure on 24 February 2009. The JPL (Jet Propulsion Laboratory) was directed to assess the options for the re-flight of the OCO instrument and recovery of the carbon-related measurement, and to understand and quantitatively assess the cost, schedule, and technical and programmatic risks of the identified options. The two most likely solutions were (1) a shared platform with the TIRS (Thermal Infrared Sensor) instrument and (2) a dedicated OSC (Orbital Sciences Corporation) LEOStar-2 spacecraft bus similar to that utilized for the original OCO mission. A joint OCO-TIRS mission study was commissioned and two specific options were examined. However, each presented technical challenges that would drive cost. It was determined that the best option was to rebuild the OCO observatory to the extent possible including another LEOStar-2 spacecraft bus. This lowest risk approach leverages the original OCO design and provides the shortest path to launch, which is targeted for no later than the February 2013 timeframe.

Episodic Memory Development: Theory of Mind Is Part of Re-Experiencing Experienced Events

ERIC Educational Resources Information Center

Perner, Josef; Kloo, Daniela; Gornik, Edith

2007-01-01

Two experiments with 3 1/2- to 6 1/2-year-old children showed that theory-of-mind development is associated with the growth of episodic memory. Episodic memory was assessed by manipulating informational conditions such that they permit or prevent the formation of episodic memories in terms of re-experiencing the recalled event. Only experienced…

Laboratory directed research and development 2006 annual report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Westrich, Henry Roger

2007-03-01

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

Phenomenal characteristics associated with projecting oneself back into the past and forward into the future: influence of valence and temporal distance.

PubMed

D'Argembeau, Arnaud; Van der Linden, Martial

2004-12-01

As humans, we frequently engage in mental time travel, reliving past experiences and imagining possible future events. This study examined whether similar factors affect the subjective experience associated with remembering the past and imagining the future. Participants mentally "re-experienced" or "pre-experienced" positive and negative events that differed in their temporal distance from the present (close versus distant), and then rated the phenomenal characteristics (i.e., sensorial, contextual, and emotional details) associated with their representations. For both past and future, representations of positive events were associated with a greater feeling of re-experiencing (or pre-experiencing) than representations of negative events. In addition, representations of temporally close events (both past and future) contained more sensorial and contextual details, and generated a stronger feeling of re-experiencing (or pre-experiencing) than representations of temporally distant events. It is suggested that the way we both remember our past and imagine our future is constrained by our current goals.

Suddenly included: cultural differences in experiencing re-inclusion.

PubMed

Pfundmair, Michaela; Graupmann, Verena; Du, Hongfei; Frey, Dieter; Aydin, Nilüfer

2015-03-01

In the current research, we examined whether re-inclusion (i.e. the change from a previous state of exclusion to a new state of inclusion) was perceived differently by people with individualistic and collectivistic cultural backgrounds. Individualists (German and Austrian participants) but not collectivists (Chinese participants) experienced re-inclusion differently than continued inclusion: While collectivistic participants did not differentiate between both kinds of inclusion, individualistic participants showed reduced fulfilment of their psychological needs under re-inclusion compared to continued inclusion. The results moreover revealed that only participants from individualistic cultures expressed more feelings of exclusion when re-included than when continually included. These exclusionary feelings partially mediated the relationship between the different states of inclusion and basic need fulfilment. © 2014 International Union of Psychological Science.

R3D-2-MSA: the RNA 3D structure-to-multiple sequence alignment server

PubMed Central

Cannone, Jamie J.; Sweeney, Blake A.; Petrov, Anton I.; Gutell, Robin R.; Zirbel, Craig L.; Leontis, Neocles

2015-01-01

The RNA 3D Structure-to-Multiple Sequence Alignment Server (R3D-2-MSA) is a new web service that seamlessly links RNA three-dimensional (3D) structures to high-quality RNA multiple sequence alignments (MSAs) from diverse biological sources. In this first release, R3D-2-MSA provides manual and programmatic access to curated, representative ribosomal RNA sequence alignments from bacterial, archaeal, eukaryal and organellar ribosomes, using nucleotide numbers from representative atomic-resolution 3D structures. A web-based front end is available for manual entry and an Application Program Interface for programmatic access. Users can specify up to five ranges of nucleotides and 50 nucleotide positions per range. The R3D-2-MSA server maps these ranges to the appropriate columns of the corresponding MSA and returns the contents of the columns, either for display in a web browser or in JSON format for subsequent programmatic use. The browser output page provides a 3D interactive display of the query, a full list of sequence variants with taxonomic information and a statistical summary of distinct sequence variants found. The output can be filtered and sorted in the browser. Previous user queries can be viewed at any time by resubmitting the output URL, which encodes the search and re-generates the results. The service is freely available with no login requirement at http://rna.bgsu.edu/r3d-2-msa. PMID:26048960

Emotional nonacceptance within the context of traumatic event exposure: The explanatory role of anxiety sensitivity for traumatic stress symptoms and disability among Latinos in a primary care setting.

PubMed

Viana, Andres G; Paulus, Daniel J; Bakhshaie, Jafar; Garza, Monica; Valdivieso, Jeanette; Ochoa-Perez, Melissa; Lemaire, Chad; Cardoso, Jodi Berger; Zvolensky, Michael J

Research has found that Latinos (versus non-Latino Whites) evince higher rates of posttraumatic stress symptoms (PTS) and posttraumatic stress disorder (PTSD), yet little attention has been given to intra-individual, emotion-related processes to explicate the higher incidence of these symptoms among Latinos. Participants included 183 trauma-exposed adult Latinos (88.5% female; Mage=37.7, SD=10.7 and 93.4% reported Spanish as their first language) who attended a community-based primary healthcare clinic in Houston. It was hypothesized that anxiety sensitivity would explain the relation between emotional nonacceptance and traumatic stress symptoms, namely re-experiencing, avoidance, and arousal difficulties as well as overall disability. Additionally, it was expected that the observed effects would be evident above and beyond the variance accounted for by number of traumas reported, gender, age, marital status, educational status, years living in the U.S., and negative affectivity. Consistent with our hypotheses, difficulties accepting negative emotions were associated with increased trauma-related re-experiencing, avoidance, and arousal difficulties. Additionally, anxiety sensitivity was an underlying mechanism in the association between emotional nonacceptance and all but one facet of traumatic stress symptoms (i.e., re-experiencing symptoms) and disability. Alternative models yielded no significant effects, providing greater confidence in the direction of the hypothesized effects. Findings are discussed in the context of their significance for informing the development of specialized intervention strategies that target anxiety sensitivity for Latinos in primary care with elevated risk for PTS and PTSD by their heightened levels of emotional nonacceptance. Copyright © 2016 Elsevier Inc. All rights reserved.

HDDTOOLS: an R package serving Hydrological Data Discovery Tools

NASA Astrophysics Data System (ADS)

Vitolo, C.; Buytaert, W.

2014-12-01

Many governmental bodies and institutions are currently committed to publish open data as the result of a trend of increasing transparency, based on which a wide variety of information produced at public expense is now becoming open and freely available to improve public involvement in the process of decision and policy making. Discovery, access and retrieval of information is, however, not always a simple task. Especially when programmatic access to data resources is not allowed, downloading metadata catalogue, select the information needed, request datasets, de-compression, conversion, manual filtering and parsing can become rather tedious. The R package "hddtools" is an open source project, designed to make all the above operations more efficient by means of re-usable functions. The package facilitate non programmatic access to various online data sources such as the Global Runoff Data Centre, NASA's TRMM mission, the Data60UK database amongst others. This package complements R's growing functionality in environmental web technologies to bridge the gap between data providers and data consumers and it is designed to be the starting building block of scientific workflows for linking data and models in a seamless fashion.

Challenges for the Urban Community College. AACJC Issues Series No. 4.

ERIC Educational Resources Information Center

Stahl, Frederick E., Ed.

Using as its premise that access and excellence are mutually interdependent goals for urban community colleges, this monograph considers the direction and nature of programmatic responses to the needs of the constituencies of urban two-year colleges and the direction and quality of the research efforts required to measure institutional impact on…

Sex Differences Research, Precision Medicine, and the Future of Women's Health

PubMed Central

Rocca, Walter A.; Faubion, Stephanie S.

2015-01-01

Abstract The National Institutes of Health's (NIH) commitment to improving health outcomes for women and men through rigorous science has been compromised by the lack of basic science evidence obtained from female animals. To correct this limitation, in June 2015 the NIH announced expectations that “sex,” as a biological variable, be included into research design and analysis in studies of vertebrate animals and humans (NOT-OD-15-102). Scientists must take the responsibility to implement this directive. However, in doing so, there is a risk that attention could be restricted to only studies of direct comparison between female/women and male/men. By contrast, understanding how sex influences health and disease needs to take a programmatic approach that includes the study of sex-specific conditions. A programmatic approach will assure the advancement of knowledge to improve women's health. PMID:26325362

Self-Directed Learning Characteristics of First-Generation, First-Year College Students Participating in a Summer Bridge Program

ERIC Educational Resources Information Center

Hall, Jeffrey D.

2011-01-01

The purpose of this study was to advance understanding of self-directed learning characteristics of first-year, first-generation college students participating in a summer bridge program. Understanding the experience of these students in higher education can lead to the development of programmatic and pedagogical strategies to better meet the…

Symmetry breaking for drag minimization

NASA Astrophysics Data System (ADS)

Roper, Marcus; Squires, Todd M.; Brenner, Michael P.

2005-11-01

For locomotion at high Reynolds numbers drag minimization favors fore-aft asymmetric slender shapes with blunt noses and sharp trailing edges. On the other hand, in an inertialess fluid the drag experienced by a body is independent of whether it travels forward or backward through the fluid, so there is no advantage to having a single preferred swimming direction. In fact numerically determined minimum drag shapes are known to exhibit almost no fore-aft asymmetry even at moderate Re. We show that asymmetry persists, albeit extremely weakly, down to vanishingly small Re, scaling asymptotically as Re^3. The need to minimize drag to maximize speed for a given propulsive capacity gives one possible mechanism for the increasing asymmetry in the body plans seen in nature, as organisms increase in size and swimming speed from bacteria like E-Coli up to pursuit predator fish such as tuna. If it is the dominant mechanism, then this signature scaling will be observed in the shapes of motile micro-organisms.

R3D-2-MSA: the RNA 3D structure-to-multiple sequence alignment server.

PubMed

Cannone, Jamie J; Sweeney, Blake A; Petrov, Anton I; Gutell, Robin R; Zirbel, Craig L; Leontis, Neocles

2015-07-01

The RNA 3D Structure-to-Multiple Sequence Alignment Server (R3D-2-MSA) is a new web service that seamlessly links RNA three-dimensional (3D) structures to high-quality RNA multiple sequence alignments (MSAs) from diverse biological sources. In this first release, R3D-2-MSA provides manual and programmatic access to curated, representative ribosomal RNA sequence alignments from bacterial, archaeal, eukaryal and organellar ribosomes, using nucleotide numbers from representative atomic-resolution 3D structures. A web-based front end is available for manual entry and an Application Program Interface for programmatic access. Users can specify up to five ranges of nucleotides and 50 nucleotide positions per range. The R3D-2-MSA server maps these ranges to the appropriate columns of the corresponding MSA and returns the contents of the columns, either for display in a web browser or in JSON format for subsequent programmatic use. The browser output page provides a 3D interactive display of the query, a full list of sequence variants with taxonomic information and a statistical summary of distinct sequence variants found. The output can be filtered and sorted in the browser. Previous user queries can be viewed at any time by resubmitting the output URL, which encodes the search and re-generates the results. The service is freely available with no login requirement at http://rna.bgsu.edu/r3d-2-msa. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

After the clinic? Researching sexual health technology in context.

PubMed

Davis, Mark

2015-01-01

There is great interest in what testing, pharmaceutical, information and social media technology can do for sexual health. Much programmatic and research activity is focused on assessing how these technologies can be used to best effect. Less obvious are analyses that place technology into historical, political and real-world settings. Developing an 'in-context' analysis of sexual health technology, this paper draws on interviews with leading community advocates, researchers and clinicians in Australia, Canada and the UK and looks across examples, including social media, rapid HIV testing, pre-Exposure Prophylaxis for HIV and polymerase chain reaction Chlamydia testing. The analysis is framed by studies of techno-society and the dialectics of sex-affirmative advocacy with biomedical authority and attends to: the rationalistic and affective dimensions of the imaginary associated with technology; the role of technology in the re-spatialisation and re-temporalisation of the sexual health clinic; and the re-invention of technology in its real-world contexts. This in-context approach is important for: the effective implementation of new technology; strengthening the social science contribution to the field; and enriching social theory in general on life in techno-societies.

The Department of Defense Congressionally Directed Medical Research Program: innovations in the federal funding of biomedical research.

PubMed

Young-McCaughan, Stacey; Rich, Irene M; Lindsay, Gaylord C; Bertram, Kenneth A

2002-04-01

In response to the lobbying efforts of the women's advocacy movement, in 1993 Congress authorized funds for a substantial increase in support of new and promising research aimed at the eradication of breast cancer. This appropriation resulted in a major expansion of the United States Army Medical Research and Materiel Command, Department of Defense Breast Cancer Research Program. The Office of Congressionally Directed Medical Research Programs was established within the United States Army Medical Research and Materiel Command to facilitate the management of the expanded extramural research program. Since that time, the programs have grown to include not just breast cancer but also prostate cancer, ovarian cancer, and neurofibromatosis. The unique appropriations to the Office of Congressionally Directed Medical Research Programs has resulted in a number of programmatic innovations. These include development of unique mechanisms of grant support, inclusion of consumer advocates on peer and programmatic review panels, and the introduction of criteria-based evaluation and scoring in peer review. This article describes these novel scientific management strategies and outlines their success in meeting program visions and goals.

Community-based counselors' interventions for elementary school-age children coping with trauma.

PubMed

Nabors, Laura; Baker-Phibbs, Christina; Woodson, Kenneth

2016-01-01

Child trauma is a mental health concern and more information is needed about treatment in community mental health settings. This article presents results of a focus group and member checking sessions held with counselors who provided therapy for children experiencing posttraumatic stress disorder in a community-based setting. Results indicated that play and art techniques were commonly used during individual child therapy sessions. Sessions were child-directed and allowed children to review trauma experiences in a "safe" setting with an "expert" guide. Several themes were commonly addressed in sessions including opportunities to re-experience, release, and reorganize the trauma, building resilience or self-esteem for the child, promoting safety, and helping the child to regulate emotional reactions and behavior problems. Counselors focused on discussing ways to interact with the child to promote healing and there was a belief that children would return to a positive developmental trajectory after coping with traumatic experiences. Future research needs to address what works for whom, in terms of what interventions are useful in child-directed counseling sessions for children who have experienced specific types of trauma, such as sexual and physical abuse or witnessing domestic violence. Integration of knowledge from evidence-based treatments will also further inform clinical practice with children who have experienced traumatic events.

People Experiencing Chronic Homelessness

MedlinePlus

... Housing Affordable Housing Rapid Re-Housing Supportive Housing Foster Education Connections Build Career Pathways Integrate Health Care ... Housing Affordable Housing Rapid Re-Housing Supportive Housing Foster Education Connections Build Career Pathways Integrate Health Care ...

Dyadic Reporting of Intimate Partner Violence Among Male Couples in Three U.S. Cities.

PubMed

Suarez, Nicolas A; Mimiaga, Matthew J; Garofalo, Robert; Brown, Emily; Bratcher, Anna Marie; Wimbly, Taylor; Hidalgo, Marco A; Hoehnle, Samuel; Thai, Jennie; Kahle, Erin; Sullivan, Patrick S; Stephenson, Rob

2018-05-01

Intimate partner violence (IPV) is a prevalent and pressing public health concern that affects people of all gender and sexual identities. Though studies have identified that male couples may experience IPV at rates as high as or higher than women in heterosexual partnerships, the body of literature addressing this population is still nascent. This study recruited 160 male-male couples in Atlanta, Boston, and Chicago to independently complete individual surveys measuring demographic information, partner violence experience and perpetration, and individual and relationship characteristics that may shape the experience of violence. Forty-six percent of respondents reported experiencing IPV in the past year. Internalized homophobia significantly increased the risk for reporting experiencing, perpetrating, or both for any type of IPV. This study is the first to independently gather data on IPV from both members of male dyads and indicates an association between internalized homophobia and risk for IPV among male couples. The results highlight the unique experiences of IPV in male-male couples and call for further research and programmatic attention to address the exorbitant levels of IPV experienced within some of these partnerships.

76 FR 13353 - Department of Commerce FY 2011-2016 Strategic Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... scorecard. A balanced scorecard ``balances'' or equally emphasizes programmatic and management objectives... senior leadership to develop a balanced scorecard to deploy and execute this Strategic Plan. The Secretary directed a balanced scorecard approach to establish and maintain focus on the Department's top...

Geospatial Brokering - Challenges and Future Directions

NASA Astrophysics Data System (ADS)

White, C. E.

2012-12-01

An important feature of many brokers is to facilitate straightforward human access to scientific data while maintaining programmatic access to it for system solutions. Standards-based protocols are critical for this, and there are a number of protocols to choose from. In this discussion, we will present a web application solution that leverages certain protocols - e.g., OGC CSW, REST, and OpenSearch - to provide programmatic as well as human access to geospatial resources. We will also discuss managing resources to reduce duplication yet increase discoverability, federated search solutions, and architectures that combine human-friendly interfaces with powerful underlying data management. The changing requirements witnessed in brokering solutions over time, our recent experience participating in the EarthCube brokering hack-a-thon, and evolving interoperability standards provide insight to future technological and philosophical directions planned for geospatial broker solutions. There has been much change over the past decade, but with the unprecedented data collaboration of recent years, in many ways the challenges and opportunities are just beginning.

Survival of the Fittest? The Re-Branding of West Virginia Higher Education

ERIC Educational Resources Information Center

Owston, James M.

2009-01-01

From 1996 to 2005, West Virginia produced the greatest percentage (56.25 percent) of institutional re-brandings in the country. In addition, the state experienced the largest proportion (25 percent) of "college-to-university" re-brandings than any other state. This study embarked on discovering possible reasons for this phenomenon and…

Division XII: Commission 55: Communicating Astronomy with the Public

NASA Astrophysics Data System (ADS)

Christensen, Lars Lindberg; Russo, Pedro; Robson, Ian; Arcand, Kimberly Kowal; Fienberg, Richard Tresch; Ödman-Govender, Carolina; Sekiguchi, Kazuhiro; Wheeler, Pete; Zhu, Jin

2015-08-01

A good fraction of the Commission 55 (C55) Organizing Committee met in Beijing in August at the XXVIII IAU General Assembly, where C55 organized Special Session 14 (SpS14) entitled ``Communicating Astronomy with the Public for Scientists.'' During our C55 business meeting, and again during an impromptu gathering a few days later, we discussed changes in the IAU's organizational and programmatic structure and how these changes might affect C55. This report summarizes key points and offers some ideas about what we're calling ``C55 v2.0.'' For background and reference, see the C55 website at http://www.communicatingastronomy.org.

Posttraumatic re-experiencing in older people: working through or covering up?

PubMed

Schreuder, J N

1996-01-01

Posttraumatic re-experiencing is a key symptom of earlier psychotraumatic experiences. It is important to establish whether we are dealing with nightmares or re-enactments. Posttraumatic nightmares are an expression of intrapsychic concerns and conflicts and, in and of themselves, need not impede exploratory psychotherapy. The nightmare entails both regression to the perceptual level of a small child and reactivation of early childhood anxieties. Before it is possible to work through the psychotraumatic experiences, it is necessary to contextualize the early childhood anxieties that are so closely related to the themes and anxieties of later life. If this is not possible, it will have to be decided to resort to therapy that rather covers up the experience and explores the current significance of the posttraumatic complaints. Posttraumatic re-enactments have an isolated position in the representational world and are accompanied by hyperarousal and intense vegetative symptoms, which is why they are considered an impediment to exploratory psychotherapy. Posttraumatic re-nactments require treatment of the symptoms before subsequent exploratory psychotherapy can be considered.

Bullying in the American Graduate Medical Education System: A National Cross-Sectional Survey

PubMed Central

2016-01-01

Objectives To deliver an estimate of bullying among residents and fellows in the United States graduate medical education system and to explore its prevalence within unique subgroups. Design/Setting/Participants A national cross-sectional survey from a sample of residents and fellows who completed an online bullying survey conducted in June 2015. The survey was distributed using a chain sampling method that relied on electronic referrals from 4,055 training programs, with 1,791 residents and fellows completing the survey in its entirety. Survey respondents completed basic demographic and programmatic information plus four general bullying and 20 specific bullying behavior questions. Between-group differences were compared for demographic and programmatic stratifications. Main Outcomes/Measures Self-reported subjected to workplace bullying from peers, attendings, nurses, ancillary staff, or patients in the past 12 months. Results Almost half of the respondents (48%) reported being subjected to bullying although both those subjected and not subjected reported experiencing ≥ 1 bullying behaviors (95% and 39% respectively). Attendings (29%) and nurses (27%) were the most frequently identified source of bullying, followed by patients, peers, consultants and staff. Attempts to belittle and undermine work and unjustified criticism and monitoring of work were the most frequently reported bullying behaviors (44% each), followed by destructive innuendo and sarcasm (37%) and attempts to humiliate (32%). Specific bullying behaviors were more frequently reported by female, non-white, shorter than < 5’8 and BMI ≥ 25 individuals. Conclusions/Relevance Many trainees report experiencing bullying in the United States graduate medical education programs. Including specific questions on bullying in the Accreditation Council for Graduate Medical Education annual resident/fellow survey, implementation of anti-bullying policies, and a multidisciplinary approach engaging all stakeholders may be of great value to eliminate these pervasive behaviors in the field of healthcare. PMID:26982705

Coping with Unexpected Events: Depression and Trauma

MedlinePlus

... indifference Inability to concentrate Recurring memories or bad dreams about the event Social withdrawal, isolation, strained personal ... Continually re-experiencing the event (“flashbacks”) through images, dreams, and/or a sense of re-living the ...

Implementation Plan. Environmental Restoration and Waste Management Programmatic Environmental Impact Statement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-01-01

In accordance with the Department of Energy`s National Environmental Policy Act implementing procedures in Volume 10 of the Code of Federal Regulations, Section 1021,312, the Environmental Restoration and Waste Management Programmatic Environmental Impact Statement Implementation Plan has two primary purposes: to provide guidance for the preparation of the Programmatic Environmental Impact Statement and to record the issues resulting from the scoping and the extended public participation process. The Implementation Plan identifies and discusses the following: background of Environmental Restoration and Waste Management activities, the purpose of the Programmatic Environmental Impact Statement, and the relationship of the Programmatic Environmental Impact Statementmore » to other Departmental initiatives (Chapter 1); need and purposes for action (Chapter 2); scoping process and results of the public participation program in defining the scope of the Programmatic Environmental Impact Statement, including a summary of the comments received and their disposition (Chapter 3); planned scope and content of the Programmatic Environmental Impact Statement (Chapter 4); consultations with other agencies and the role of cooperating agencies (Chapter 5); planned schedule of major Programmatic Environmental Impact Statement milestones (Chapter 6); and responsibilities for preparation of the Programmatic Environmental Impact Statement (Chapter 7).« less

Philip Morris' new scientific initiative: an analysis

PubMed Central

HIRSCHHORN, N.; BIALOUS, S. A.; SHATENSTEIN, S.

2001-01-01

In the fall of 2000, Philip Morris re-initiated an external research grants programme ("Philip Morris External Research Program", or PMERP), the first since the dissolution of the Council for Tobacco Research (CTR) and the Center for Indoor Air Research (CIAR). The ostensible purpose of the programme is to help develop cigarette designs "that might reduce the health risk of smoking". Internal company documents also indicate that Philip Morris urgently seeks to restore its scientific "credibility", as part of a "new openness" in relation to the external community. The structure of the review panel—a cohort of external peer reviewers, a science advisory board, and an internal, anonymous review and approvals committee—is nearly identical to that of the CIAR. The majority of the named reviewers have had previous affiliation with the tobacco industry either as reviewers or grantees, but only a minority have done research directly on tobacco or smoking. The programmatic substance of the PMERP could be interpreted as soliciting exculpatory evidence with respect to smoking and exposure to smoke. We remain sceptical about the scientific integrity of PMERP.


Keywords: Philip Morris; scientific credibility; tobacco industry PMID:11544389

ACHP | News | St. Elizabeths Programmatic Agreement Signed

Science.gov Websites

Search skip specific nav links Home arrow News arrow St. Elizabeths Programmatic Agreement Signed St . Elizabeths Programmatic Agreement Signed December 9, 2008-- The General Services Administration (GSA), the ), and the Department of Homeland Security (DHS) executed a Programmatic Agreement (PA) for the

Perspectives in Peer Programs. Volume 28, Number 1, Winter 2018

ERIC Educational Resources Information Center

Tindall, Judith, Ed.; Black, David R., Ed.; Routson, Sue, Ed.

2018-01-01

This issue of "Perspectives in Peer Programs," the official journal of the National Association of Peer Program Professionals (NAPP), includes: (1) Introduction to this Issue on NAPPP Programmatic Standards Checklist, Programmatic Standards, Ethics, and Rubric; (2) NAPPP Programmatic Standards Checklist; (3) NAPPP Programmatic Standards;…

75 FR 78980 - Notice of Availability of the Draft Programmatic Environmental Impact Statement for Solar Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-17

...] Notice of Availability of the Draft Programmatic Environmental Impact Statement for Solar Energy... Draft Programmatic Environmental Impact Statement (EIS) for Solar Energy Development in Six Southwestern... preferred method of commenting. Mail: Addressed to: Solar Energy Draft Programmatic EIS, Argonne National...

ACHP | News | Nationwide Programmatic Agreement Streamlines 106 Process for

Science.gov Websites

Publications Search skip specific nav links Home arrow News arrow Nationwide Programmatic Agreement Streamlines 106 Process for NPS Nationwide Programmatic Agreement Streamlines 106 Process for NPS Pursuant to Service (NPS) on November 14, 2008, executed a nationwide Programmatic Agreement (PA) with the Advisory

77 FR 36998 - Notice of Availability of a Draft Programmatic Environmental Assessment for Office of Coast...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-20

... Draft Programmatic Environmental Assessment for Office of Coast Survey Hydrographic Survey Projects... Programmatic Environmental Assessment; Request for comments. SUMMARY: NOAA's Office of Coast Survey (OCS) seeks comment on a draft programmatic environmental assessment (PEA) of the hydrographic surveys and related...

75 FR 38822 - Notice of Intent To Prepare Four Programmatic Environmental Impact Statements for the Northern...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

... Four Programmatic Environmental Impact Statements for the Northern Border Between the United States and...: Notice of Intent to Prepare Programmatic Environmental Impact Statements; Request for Comments; and... four Programmatic Environmental Impact Statements (PEISs) to identify and assess potential impacts upon...

Flextime: A Viable Solution to Work/Family Conflict?

ERIC Educational Resources Information Center

Christensen, Kathleen E.; Staines, Graham L.

1990-01-01

Reviews research regarding advantages and disadvantages of flextime to both employers and employees; evaluates effects of flextime on resolving work/family conflicts; and establishes future programmatic, research, and policy directions regarding flextime. Claims flextime is beneficial in resolving work/family conflicts but not as beneficial as…

Report: Audits on EPA Recovery Act-Funded Diesel Emission Reduction Act Assistance Agreements Reported Programmatic and Management Challenges

EPA Pesticide Factsheets

Report #14-R-0355, September 15, 2014. EPA should consider the issues identified in our prior reports as it takes actions directed by the Office of Management and Budget to assess risk inherent in its programs.

Programmatic Environmental Assessment for Army 2020 Force Structure Realignment

DTIC Science & Technology

2012-11-01

Campbell. 35 • Energy Demand and Generation. Implementation of Alternative 1 would provide 36 beneficial effects to energy consumption on the...have direct effects to the inhabitants ( fish , invertebrates) and indirect effects to the 20 wildlife that forage for food in these areas. JBER...Impacts to water quality have direct 33 effects to the inhabitants ( fish , invertebrates) and indirect effects to the wildlife that forage for 34 food in

Differential predictive value of PTSD symptom clusters for mental health care among Iraq and Afghanistan veterans following PTSD diagnosis.

PubMed

Smith, Noelle B; Tsai, Jack; Pietrzak, Robert H; Cook, Joan M; Hoff, Rani; Harpaz-Rotem, Ilan

2017-10-01

Veterans from the recent conflicts in Iraq and Afghanistan are being diagnosed with posttraumatic stress disorder (PTSD) at high rates. This study examined characteristics associated with mental health service utilization, specifically psychotherapy, through the Department of Veterans Affairs (VA), in a large cohort of Iraq and Afghanistan veterans newly diagnosed with PTSD. This study utilized national VA administrative data from Iraq and Afghanistan veterans following an initial diagnosis of PTSD and completed a self-report measure of PTSD symptoms between Fiscal Years 2008-2012 (N=52,456; 91.7% male; 59.7% Caucasian; mean age 30.6, SD=8.3). Regression analyses examined the relation between PTSD symptom cluster severity and treatment-related variables. Accounting for demographic/clinical variables, PTSD symptom clusters were related to psychotherapy initiation (re-experiencing, OR=1.23; numbing, OR=1.15), combination treatment (medication and psychotherapy; re-experiencing, OR=1.13; avoidance, OR=1.07; dysphoric arousal, OR=1.06), number of psychotherapy visits (re-experiencing, IRR= 1.08; numbing, IRR=1.09), and adequate dose of therapy (e.g., 8 visits/14 weeks; re-experiencing: OR= 1.07). When considering treatment approaches for trauma-exposed veterans, it is important to map the severity of unique PTSD symptoms clusters; this may have implications on the selection of treatment that best fits the veterans' needs and preferences (e.g., exposure therapy versus cognitive processing therapy). Published by Elsevier B.V.

76 FR 36097 - Notice of Intent To Prepare a Programmatic Environmental Impact Statement for the U.S. Department...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

... DEPARTMENT OF ENERGY Notice of Intent To Prepare a Programmatic Environmental Impact Statement for...: Notice of intent to prepare a programmatic environmental impact statement for the DOE Uranium Leasing Program. SUMMARY: DOE announces its intent to prepare a Programmatic Environmental Impact Statement (PEIS...

GIANT API: an application programming interface for functional genomics

PubMed Central

Roberts, Andrew M.; Wong, Aaron K.; Fisk, Ian; Troyanskaya, Olga G.

2016-01-01

GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. PMID:27098035

Technologies of the '80s: Their Impact on Vocational Agriculture Occupations.

ERIC Educational Resources Information Center

Jaffe, J. A., Ed.; And Others

This report is one of seven that identify major new and emerging technological advances expected to influence major vocational education program areas and to describe the programmatic implications in terms of skill-knowledge requirements, occupations most directly affected, and the anticipated diffusion rate. Chapter 1 considers technology as…

Technologies of the '80s: Their Impact on Technical Occupations.

ERIC Educational Resources Information Center

Jaffe, J. A., Ed.; And Others

This report is one of seven that identify major new and emerging technological advances expected to influence major vocational education program areas and to describe the programmatic implications in terms of skill-knowledge requirements, occupations most directly affected, and the anticipated diffusion rate. Chapter 1 considers technology as…

Technologies of the '80s: Their Impact on Office Occupations.

ERIC Educational Resources Information Center

Jaffe, J. A., Ed.; And Others

This report is one of seven that identify major new and emerging technological advances expected to influence major vocational education program areas and to describe the programmatic implications in terms of skill-knowledge requirements, occupations most directly affected, and the anticipated diffusion rate. Chapter 1 considers technology as…

Strategic Directions for Extension Health and Wellness Programs

ERIC Educational Resources Information Center

Rodgers, Michelle; Braun, Bonnie

2015-01-01

The new Cooperative Extension National Framework for Health and Wellness is a tool to help Extension systematically address the programmatic area of health and wellness at the individual, community, environmental, and policy levels. Key strategies of the framework tool are provided and suggestions for ways that Extension can use this framework…

State of the States in Developmental Disabilities

ERIC Educational Resources Information Center

Braddock, David; Hemp, Richard; Rizzolo, Mary Kay

2008-01-01

This is the latest edition of the "State of the States in Developmental Disabilities" study--a thorough and the only one of its kind investigation on public spending, revenues, and programmatic trends of intellectual and developmental programs and services within the United States since 1977. Directed by leading researcher, Dr. David…

Patient satisfaction with maxillofacial prosthesis. Literature review.

PubMed

Goiato, Marcelo Coelho; Pesqueira, Aldiéris Alves; Ramos da Silva, Cristina; Gennari Filho, Humberto; Micheline Dos Santos, Daniela

2009-02-01

Obturators and facial prostheses are important not only in rehabilitation and aesthetics, but also in patient re-socialisation. The level of reintegration is directly related to the degree of satisfaction with rehabilitation. So, the maxillofacial prosthetics must provide patient satisfaction during treatment. This study aimed to search information in database and conduct a literature review on patient satisfaction with maxillofacial prosthesis. The problems experienced by these patients may decrease when specialists keep the patient on regular inspection. Rehabilitation through alloplasty or prosthetic restoration provides satisfactory conditions in aesthetics and well-being and reinstates individuals in familial and social environment.

Spirituality and Resilience Among Mexican American IPV Survivors.

PubMed

de la Rosa, Iván A; Barnett-Queen, Timothy; Messick, Madeline; Gurrola, Maria

2016-12-01

Women with abusive partners use a variety of coping strategies. This study examined the correlation between spirituality, resilience, and intimate partner violence using a cross-sectional survey of 54 Mexican American women living along the U.S.-Mexico border. The meaning-making coping model provides the conceptual framework to explore how spirituality is used as a copying strategy. Multiple ordinary least squares (OLS) regression results indicate women who score higher on spirituality also report greater resilient characteristics. Poisson regression analyses revealed that an increase in level of spirituality is associated with lower number of types of abuse experienced. Clinical, programmatic, and research implications are discussed. © The Author(s) 2015.

Experiencing Past and Future Personal Events: Functional Neuroimaging Evidence on the Neural Bases of Mental Time Travel

ERIC Educational Resources Information Center

Botzung, Anne; Denkova, Ekaterina; Manning, Lilianne

2008-01-01

Functional MRI was used in healthy subjects to investigate the existence of common neural structures supporting re-experiencing the past and pre-experiencing the future. Past and future events evocation appears to involve highly similar patterns of brain activation including, in particular, the medial prefrontal cortex, posterior regions and the…

Re-operative thyroid surgery: a 20-year prospective cohort study at a tertiary referral centre.

PubMed

Hardman, John C; Smith, J A; Nankivell, P; Sharma, N; Watkinson, J C

2015-06-01

Re-operative thyroid surgery is a relatively uncommon procedure complicated by distorted anatomy and post-operative tissue changes. Surgery may follow initial benign or malignant pathology. Published outcomes vary widely in the literature. This study aims to report our outcomes from re-operative thyroid surgery. Patient demographics and complication rates for consecutive thyroidectomies performed by a single surgeon at a tertiary centre were collected between 1993 and 2013. Outcomes in re-operative surgery are analysed and compared with local and national data. Cases of re-operative surgery following benign disease are further analysed for histology, re-presenting symptoms and time between procedures. Our cohort comprised 1,657 cases including 164 re-operative procedures (101 malignant, 63 benign). Within our cohort re-operative cases were on average 4 years older (mean 49.9 vs 45.9 years, p = 0.001) and had a higher incidence of haematoma formation (4.3 vs 1.7 %, p = 0.033) and transient recurrent laryngeal nerve palsy (5.5 vs 2.5 %, p = 0.044) compared to primary surgery. Rates of permanent hypocalcaemia (2.4 vs 1.8 %, p = 0.540) and permanent RLN palsy (1.8 vs 0.4 %, p = 0.051) were higher in the re-operative group but did not reach significance. Comparison of complications following re-operation for benign and malignant disease revealed no significant differences. Mean interval to re-operation for benign cases was 17.4 years with 74.6 % found to have multinodular goitre at repeat procedure. Re-operative procedures comprised around 10 % of thyroid surgery at our centre. Re-operative cases experienced more complications than primary surgery but permanent rates were low. Re-operative surgery may therefore be safely considered in experienced hands.

77 FR 10803 - Intent of Preparation of a Programmatic Environmental Assessment, To Open a Public Scoping Period...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... Preparation of a Programmatic Environmental Assessment, To Open a Public Scoping Period, and To Conduct Public... Intent of Preparation of a Programmatic Environmental Assessment, to Open a Public Scoping Period, and to...), of the U.S. Department of Transportation (U.S. DOT), will prepare a Programmatic Environmental...

Educational affairs plan: A five-year strategy

NASA Technical Reports Server (NTRS)

1987-01-01

A five-year plan is presented to guide the use of NASA resources in administering a focused and consistent set of aeronautics and space science education programs. Major initiatives outlined in this plan fall into two categories: programmatic priorities and institutional priorities. Programmatic priorities for this plan include elementary education, teacher education, underrepresented minority participation, educational technology and the Aerospace Education Services Project (AESP). Institutional priorities highlighted in this plan include university programs, educational publications and their distribution, educational partnerships with public and private organizations, educational research and evaluation, and activities of the educational affairs administration. The plan's aim is to directly and indirectly help to ensure an adequate pool of talented scientists, engineers and technical personnel to keep NASA at the forefront of advancements for the 21st century.

Cost of providing injectable contraceptives through a community-based social marketing program in Tigray, Ethiopia.

PubMed

Prata, Ndola; Downing, Janelle; Bell, Suzanne; Weidert, Karen; Godefay, Hagos; Gessessew, Amanuel

2016-06-01

To provide a cost analysis of an injectable contraceptive program combining community-based distribution and social marketing in Tigray, Ethiopia. We conducted a cost analysis, modeling the costs and programmatic outcomes of the program's initial implementation in 3 districts of Tigray, Ethiopia. Costs were estimated from a review of program expense records, invoices, and interviews with health workers. Programmatic outcomes include number of injections and couple-year of protection (CYP) provided. We performed a sensitivity analysis on the average number of injections provided per month by community health workers (CHWs), the cost of the commodity, and the number of CHWs trained. The average programmatic CYP was US $17.91 for all districts with a substantial range from US $15.48-38.09 per CYP across districts. Direct service cost was estimated at US $2.96 per CYP. The cost per CYP was slightly sensitive to the commodity cost of the injectable contraceptives and the number of CHWs. The capacity of each CHW, measured by the number of injections sold, was a key input that drove the cost per CYP of this model. With a direct service cost of US $2.96 per CYP, this study demonstrates the potential cost of community-based social marketing programs of injectable contraceptives. The findings suggest that the cost of social marketing of contraceptives in rural communities is comparable to other delivery mechanisms with regards to CYP, but further research is needed to determine the full impact and cost-effectiveness for women and communities beyond what is measured in CYP. Copyright © 2016 Elsevier Inc. All rights reserved.

M(o)TOR of aging: MTOR as a universal molecular hypothalamus.

PubMed

Blagosklonny, Mikhail V

2013-07-01

A recent ground-breaking publication described hypothalamus-driven programmatic aging. As a Russian proverb goes "everything new is well-forgotten old". In 1958, Dilman proposed that aging and its related diseases are programmed by the hypothalamus. This theory, supported by beautiful experiments, remained unnoticed just to be re-discovered recently. Yet, it does not explain all manifestations of aging. And would organism age without hypothalamus? Do sensing pathways such as MTOR (mechanistic Target of Rapamycin) and IKK-beta play a role of a "molecular hypothalamus" in every cell? Are hypothalamus-driven alterations simply a part of quasi-programmed aging manifested by hyperfunction and secondary signal-resistance? Here are some answers.

Technologies of the '80s: Their Impact on Trade and Industrial Occupations.

ERIC Educational Resources Information Center

Jaffe, J. A., Ed.; And Others

This report is one of seven that identify major new and emerging technological advances expected to influence major vocational education program areas and to describe the programmatic implications in terms of skill-knowledge requirements, occupations most directly affected, and the anticipated diffusion rate. Chapter 1 considers technology as…

Programmatic Environmental Assessment (EA) for Minor Construction Projects at F. E. Warren Air Force Base, Wyoming

DTIC Science & Technology

2013-06-01

water quality or increase storm water runoff. Adherence to all applicable local , state and federal laws regarding storm water mitigates any direct...during construction will mitigate any hazard. 7 .1.4 Water Resources: 7.1.4.1 Storm Water: New construction has the potential to degrade storm

Programmatic Environmental Assessment (EA) for Minor Construction Projects at F. E. Warren Air Force Base, Wyoming

DTIC Science & Technology

2013-08-07

water quality or increase storm water runoff. Adherence to all applicable local , state and federal laws regarding storm water mitigates any direct...during construction will mitigate any hazard. 7 .1.4 Water Resources: 7.1.4.1 Storm Water: New construction has the potential to degrade storm

Palliative Care: The Relief You Need When You're Experiencing Symptoms of Serious Illness

MedlinePlus

... You Have a Serious Illness PALLIATIVE CARE: Improving quality of life when you’re seriously ill. Dealing with any ... your pain and other symptoms and improve your quality of life. Palliative care is a central part of treatment ...

Assessing the Ability of a VR-Based Assembly Task Simulation to Evaluate Physical Risk Factors.

PubMed

Pontonnier, Charles; Samani, Afshin; Badawi, Marwan; Madeleine, Pascal; Dumont, Georges

2014-05-01

Nowadays the process of workstation design tends to include assessment steps in a virtual environment (VE) to evaluate the ergonomic features. These approaches are cost-effective and convenient since working directly on the digital mock-up in a VE is preferable to constructing a real physical mock-up in a real environment (RE). This study aimed at understanding the ability of a VR-based assembly tasks simulator to evaluate physical risk factors in ergonomics. Sixteen subjects performed simplified assembly tasks in RE and VE. Motion of the upper body and five muscle electromyographic activities were recorded to compute normalized and averaged objective indicators of discomfort, that is, rapid upper limb assessment score, averaged muscle activations, and total task time. Rated perceived exertion (RPE) and a questionnaire were used as subjective indicators of discomfort. The timing regime and complexity of the assembly tasks were investigated as within-subject factors. The results revealed significant differences between measured indicators in RE and VE. While objective measures indicated lower activity and exposure in VE, the subjects experienced more discomfort than in RE. Fairly good correlation levels were found between RE and VE for six of the objective indicators. This study clearly demonstrates that ergonomic studies of assembly tasks using VR are still challenging. Indeed, objective and subjective measurements of discomfort that are usually used in ergonomics to minimize the risks of work-related musculoskeletal disorders development exhibit opposite trends in RE and VE. Nevertheless, the high level of correlation found during this study indicates that the VR-based simulator can be used for such assessments.

Factor structure of PTSD, and relation with gender in trauma survivors from India.

PubMed

Charak, Ruby; Armour, Cherie; Elklit, Ask; Angmo, Disket; Elhai, Jon D; Koot, Hans M

2014-01-01

The factor structure of posttraumatic stress disorder (PTSD) has been extensively studied in Western countries. Some studies have assessed its factor structure in Asia (China, Sri Lanka, and Malaysia), but few have directly assessed the factor structure of PTSD in an Indian adult sample. Furthermore, in a largely patriarchal society in India with strong gender roles, it becomes imperative to assess the association between the factors of PTSD and gender. The purpose of the present study was to assess the factor structure of PTSD in an Indian sample of trauma survivors based on prevailing models of PTSD defined in the DSM-IV-TR (APA, 2000), and to assess the relation between PTSD factors and gender. The sample comprised of 313 participants (55.9% female) from Jammu and Kashmir, India, who had experienced a natural disaster (N=200) or displacement due to cross-border firing (N=113). Three existing PTSD models-two four-factor models (Emotional Numbing and Dysphoria), and a five-factor model (Dysphoric Arousal)-were tested using Confirmatory Factor Analysis with addition of gender as a covariate. The three competing models had similar fit indices although the Dysphoric Arousal model fit significantly better than Emotional Numbing and Dysphoria models. Gender differences were found across the factors of Re-experiencing and Anxious arousal. Findings indicate that the Dysphoric Arousal model of PTSD was the best model; albeit the fit indices of all models were fairly similar. Compared to males, females scored higher on factors of Re-experiencing and Anxious arousal. Gender differences found across two factors of PTSD are discussed in light of the social milieu in India.

Factor structure of PTSD, and relation with gender in trauma survivors from India

PubMed Central

Charak, Ruby; Armour, Cherie; Elklit, Ask; Angmo, Disket; Elhai, Jon D.; Koot, Hans M.

2014-01-01

Background The factor structure of posttraumatic stress disorder (PTSD) has been extensively studied in Western countries. Some studies have assessed its factor structure in Asia (China, Sri Lanka, and Malaysia), but few have directly assessed the factor structure of PTSD in an Indian adult sample. Furthermore, in a largely patriarchal society in India with strong gender roles, it becomes imperative to assess the association between the factors of PTSD and gender. Objective The purpose of the present study was to assess the factor structure of PTSD in an Indian sample of trauma survivors based on prevailing models of PTSD defined in the DSM-IV-TR (APA, 2000), and to assess the relation between PTSD factors and gender. Method The sample comprised of 313 participants (55.9% female) from Jammu and Kashmir, India, who had experienced a natural disaster (N=200) or displacement due to cross-border firing (N=113). Results Three existing PTSD models—two four-factor models (Emotional Numbing and Dysphoria), and a five-factor model (Dysphoric Arousal)—were tested using Confirmatory Factor Analysis with addition of gender as a covariate. The three competing models had similar fit indices although the Dysphoric Arousal model fit significantly better than Emotional Numbing and Dysphoria models. Gender differences were found across the factors of Re-experiencing and Anxious arousal. Conclusions Findings indicate that the Dysphoric Arousal model of PTSD was the best model; albeit the fit indices of all models were fairly similar. Compared to males, females scored higher on factors of Re-experiencing and Anxious arousal. Gender differences found across two factors of PTSD are discussed in light of the social milieu in India. PMID:25413575

Intolerance of uncertainty and post-traumatic stress symptoms: An investigation within a treatment seeking trauma-exposed sample.

PubMed

Oglesby, Mary E; Gibby, Brittany A; Mathes, Brittany M; Short, Nicole A; Schmidt, Norman B

2017-01-01

Intolerance of uncertainty (IU) has been associated with post-traumatic stress symptoms (PTSS) in the literature. However, no research to date has investigated the relationship between IU and PTSS within a clinical trauma-exposed sample, which is an important next step in the literature and crucial for the generalizability of these findings. Therefore, the current study hypothesized that IU would be related to increased PTSS within a clinical sample of trauma-exposed individuals. Further, we hypothesized that IU would be related to elevated PTSS after accounting for anxiety sensitivity (AS) and negative affect (NA), two known correlates of PTSS. Finally, we examined the relations between IU and the PTSS clusters (i.e., avoidance, emotional numbing, hyperarousal, and re-experiencing) while covarying for AS and NA. Participants included community adults (n=126) presenting at an outpatient clinic. All participants had previously experienced a traumatic event as defined by the DSM-5 PTSD Criterion A. Results revealed that IU was significantly associated with increased PTSS above and beyond AS and NA. Further, results indicated that IU was significantly related to the avoidance, hyperarousal, and emotional numbing PTSS clusters, even after covarying for AS and NA. IU was not significantly associated with the PTSS re-experiencing cluster once AS and NA were taken into account. Our results expand upon the extant literature by demonstrating that IU is associated with PTSS above and beyond AS and NA within a clinical trauma-exposed sample. These findings are discussed in terms of promising directions for future research and treatment strategies. Copyright © 2016 Elsevier Inc. All rights reserved.

The letters of Alix Joffroy (1844-1908), a medical intern at Lariboisière's Hospital at the time of the Commune of Paris.

PubMed

Tiberghien, Denis

2016-02-01

Since opening in 1848, Lariboisière's Hospital was strongly associated with the history of Paris and especially with the terrible days of the siege of Paris and the fights of the Commune. On the day after the surrender, Alix Joffroy wrote his first letter to his mother. He described the events as he experienced them, expressing his feelings about the causes of this political and military disaster and his experience there as an intern. Some weeks after the defeat of France by the Prussians, humbled Parisians attacked governmental troops. From March to May 1871 an improvised insurrectionary movement, The Commune of Paris, had taken power in the capital During the Bloody Week from 21 to 28 May 1871; this movement was suppressed by the Versaillaise Army. In his second letter, Joffroy related with great realism the tooth and nail fighting at the barricades and then the savage repression by the Army of the Communards around Lariboisière's Hospital. Two letters preciously preserved by Alix Joffroy's descendants give this man's unique direct account of a tragic period of the 19th century. © The Author(s) 2014.

76 FR 61295 - Programmatic Environmental Assessment

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

...-1608] Programmatic Environmental Assessment AGENCY: Federal Communications Commission. ACTION: Proposed... time to file comments in response to a draft programmatic environmental assessment (PEA) of the Antenna Structure Registration (ASR) program. The purpose of the PEA is to evaluate the potential environmental...

Confirmatory factor analysis of posttraumatic stress symptoms in sexually harassed women.

PubMed

Palmieri, Patrick A; Fitzgerald, Louise F

2005-12-01

Posttraumatic stress disorder (PTSD) factor analytic research to date has not provided a clear consensus on the structure of posttraumatic stress symptoms. Seven hypothesized factor structures were evaluated using confirmatory factor analysis of the Posttraumatic Stress Disorder Checklist, a paper-and-pencil measure of posttraumatic stress symptom severity, in a sample of 1,218 women who experienced a broad range of workplace sexual harassment. The model specifying correlated re-experiencing, effortful avoidance, emotional numbing, and hyperarousal factors provided the best fit to the data. Virtually no support was obtained for the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV; American Psychiatric Association, 1994) three-factor model of re-experiencing, avoidance, and hyperarousal factors. Different patterns of correlations with external variables were found for the avoidance and emotional numbing factors, providing further validation of the supported model.

NRCS Prototype Programmatic Agreement FAQ

Science.gov Websites

Search Frequently Asked Questions regarding the Natural Resources Conservation Service Prototype Programmatic Agreement The Advisory Council on Historic Preservation (ACHP) recently designated a prototype programmatic agreement (PPA) for the United States Department of Agriculture, Natural Resources Conservation

Programmatic Instructional Development.

ERIC Educational Resources Information Center

Schutz, Richard E.

Programmatic instructional development refers to sequenced and coordinated efforts to produce effective instructional programs which cumulate over time and which attain outcomes that would be impossible under non-programmatic projects. As practiced at the Southwest Regional Laboratory (SWRL), it involves the combined efforts of specialists from…

Staff Report to the Senior Department Official on Recognition Compliance Issues. Recommendation Page: Midwifery Education Accreditation Council

ERIC Educational Resources Information Center

US Department of Education, 2010

2010-01-01

The Midwifery Education Accreditation Council (MEAC) is both a programmatic and an institutional accreditor. It accredits direct-entry midwifery educational programs and institutions awarding degrees and certificates throughout the United States. MEAC accredits or pre-accredits two programs and eight institutions located in nine states. Four of…

Building a Social Movement for Education in England: Policy and Strategy

ERIC Educational Resources Information Center

Hatcher, Richard

2015-01-01

This article addresses the programmatic and strategic choices facing the progressive and left movement in education after the May general election. It draws a critical balance sheet of the education policies in Labour's election manifesto and of the strategy of attempting to influence them in a more progressive direction. An analysis of the…

The Mediating Role of Intercultural Wonderment: Connecting Programmatic Components to Global Outcomes in Study Abroad

ERIC Educational Resources Information Center

Engberg, Mark E.; Jourian, T. J.; Davidson, Lisa M.

2016-01-01

This study examines the mediating role of intercultural wonderment in relation to students' development of a global perspective. We utilize both confirmatory factor analysis and structural equation modeling to validate the intercultural wonderment construct and test the direct and indirect effects of the structural pathways in the model,…

Diet and Obesity Issues in the Underserved.

PubMed

Mejia de Grubb, Maria C; Levine, Robert S; Zoorob, Roger J

2017-03-01

The goal of this article is to inform new directions for addressing inequalities associated with obesity by reviewing current issues about diet and obesity among socioeconomically vulnerable and underserved populations. It highlights recent interventions in selected high-risk populations, as well as gaps in the knowledge base. It identifies future directions in policy and programmatic interventions to expand the role of primary care providers, with an emphasis on those aimed at preventing obesity and promoting healthy weight. Copyright © 2016 Elsevier Inc. All rights reserved.

Feasibility of re-biopsy and EGFR mutation analysis in patients with non-small cell lung cancer.

PubMed

Kim, Tae-Ok; Oh, In-Jae; Kho, Bo Gun; Park, Ha Young; Chang, Jin Sun; Park, Cheol-Kyu; Shin, Hong-Joon; Lim, Jung-Hwan; Kwon, Yong-Soo; Kim, Yu-Il; Lim, Sung-Chul; Kim, Young-Chul; Choi, Yoo-Duk

2018-05-14

In cases of EGFR-tyrosine kinase inhibitor (TKI) failure, re-biopsy may be useful to understand resistance mechanisms and guide further treatment decisions. However, performing re-biopsy is challenging because of several hurdles. We assessed the feasibility of re-biopsy in advanced non-small cell lung cancer (NSCLC) patients in real-world clinical practice. We retrospectively reviewed the clinical and pathologic data of advanced NSCLC patients who experienced disease progression after previous treatment with EGFR-TKIs at a single tertiary hospital in Korea between January 2014 and December 2016. Re-biopsy specimens included small biopsy, surgical tissue, or liquid-based cytology. EGFR mutation was tested using peptide nucleic acid-mediated clamping PCR. Of the 230 NSCLC patients that experienced progression after EGFR-TKI therapy, 105 (45.7%) underwent re-biopsy. Re-biopsy was successfully performed in 94 (89.5%) patients, and 11 patients were diagnosed with no malignancy. The complication rate was 8.6%, including seven cases of pneumothorax. EGFR mutation testing was performed on 75 patients using re-biopsy specimens. Of the 57 patients who had sensitizing mutations at diagnosis, T790M mutations were found in 19 (33.3%), while 38 (66.7%) had no T790M mutation. Multivariate analysis showed that the re-biopsy group was younger (P = 0.002) and exhibited a previous response to EGFR-TKIs (P < 0.001). Re-biopsy in advanced NSCLC is feasible in real world clinical practice, particularly in younger patients and those who achieved a previous response to EGFR-TKIs. © 2018 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.

Inertial migrations of cylindrical particles in rectangular microchannels: Variations of equilibrium positions and equivalent diameters

NASA Astrophysics Data System (ADS)

Su, Jinghong; Chen, Xiaodong; Hu, Guoqing

2018-03-01

Inertial migration has emerged as an efficient tool for manipulating both biological and engineered particles that commonly exist with non-spherical shapes in microfluidic devices. There have been numerous studies on the inertial migration of spherical particles, whereas the non-spherical particles are still largely unexplored. Here, we conduct three-dimensional direct numerical simulations to study the inertial migration of rigid cylindrical particles in rectangular microchannels with different width/height ratios under the channel Reynolds numbers (Re) varying from 50 to 400. Cylindrical particles with different length/diameter ratios and blockage ratios are also concerned. Distributions of surface force with the change of rotation angle show that surface stresses acting on the particle end near the wall are the major contributors to the particle rotation. We obtain lift forces experienced by cylindrical particles at different lateral positions on cross sections of two types of microchannels at various Re. It is found that there are always four stable equilibrium positions on the cross section of a square channel, while the stable positions are two or four in a rectangular channel, depending on Re. By comparing the equilibrium positions of cylindrical particles and spherical particles, we demonstrate that the equivalent diameter of cylindrical particles monotonously increases with Re. Our work indicates the influence of a non-spherical shape on the inertial migration and can be useful for the precise manipulation of non-spherical particles.

(Re)Imagining Gender

ERIC Educational Resources Information Center

Sanders, James H., III

2010-01-01

Briden Cole Schueren, a 21-year-old Columbus State University visual art student, was born female-bodied. His recent artworks have explored the transitions he is experiencing and confronts the transphobic and heteronormative violence experienced in a state that denies equal protection and human rights to LGBT youth. This profile of Briden Cole…

Systems Engineering Design Via Experimental Operation Research: Complex Organizational Metric for Programmatic Risk Environments (COMPRE)

NASA Technical Reports Server (NTRS)

Mog, Robert A.

1999-01-01

Unique and innovative graph theory, neural network, organizational modeling, and genetic algorithms are applied to the design and evolution of programmatic and organizational architectures. Graph theory representations of programs and organizations increase modeling capabilities and flexibility, while illuminating preferable programmatic/organizational design features. Treating programs and organizations as neural networks results in better system synthesis, and more robust data modeling. Organizational modeling using covariance structures enhances the determination of organizational risk factors. Genetic algorithms improve programmatic evolution characteristics, while shedding light on rulebase requirements for achieving specified technological readiness levels, given budget and schedule resources. This program of research improves the robustness and verifiability of systems synthesis tools, including the Complex Organizational Metric for Programmatic Risk Environments (COMPRE).

78 FR 17653 - Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-22

... infrastructure development, including siting wind turbines, access roads, underground collector lines, overhead... Wildlife Service Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS... Plains Wind Energy Draft Programmatic Environmental Impact Statement (Draft [[Page 17654

A Practical Approach to Programmatic Assessment Design

ERIC Educational Resources Information Center

Timmerman, A. A.; Dijkstra, J.

2017-01-01

Assessment of complex tasks integrating several competencies calls for a programmatic design approach. As single instruments do not provide the information required to reach a robust judgment of integral performance, 73 guidelines for programmatic assessment design were developed. When simultaneously applying these interrelated guidelines, it is…

7 CFR 3570.85 - Programmatic changes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Programmatic changes. 3570.85 Section 3570.85... AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.85 Programmatic changes. The grantee shall obtain prior Agency approval for any change to the objectives of the approved project. (For...

GIANT API: an application programming interface for functional genomics.

PubMed

Roberts, Andrew M; Wong, Aaron K; Fisk, Ian; Troyanskaya, Olga G

2016-07-08

GIANT API provides biomedical researchers programmatic access to tissue-specific and global networks in humans and model organisms, and associated tools, which includes functional re-prioritization of existing genome-wide association study (GWAS) data. Using tissue-specific interaction networks, researchers are able to predict relationships between genes specific to a tissue or cell lineage, identify the changing roles of genes across tissues and uncover disease-gene associations. Additionally, GIANT API enables computational tools like NetWAS, which leverages tissue-specific networks for re-prioritization of GWAS results. The web services covered by the API include 144 tissue-specific functional gene networks in human, global functional networks for human and six common model organisms and the NetWAS method. GIANT API conforms to the REST architecture, which makes it stateless, cacheable and highly scalable. It can be used by a diverse range of clients including web browsers, command terminals, programming languages and standalone apps for data analysis and visualization. The API is freely available for use at http://giant-api.princeton.edu. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

ProbOnto: ontology and knowledge base of probability distributions.

PubMed

Swat, Maciej J; Grenon, Pierre; Wimalaratne, Sarala

2016-09-01

Probability distributions play a central role in mathematical and statistical modelling. The encoding, annotation and exchange of such models could be greatly simplified by a resource providing a common reference for the definition of probability distributions. Although some resources exist, no suitably detailed and complex ontology exists nor any database allowing programmatic access. ProbOnto, is an ontology-based knowledge base of probability distributions, featuring more than 80 uni- and multivariate distributions with their defining functions, characteristics, relationships and re-parameterization formulas. It can be used for model annotation and facilitates the encoding of distribution-based models, related functions and quantities. http://probonto.org mjswat@ebi.ac.uk Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

75 FR 21650 - Coral Reef Restoration Plan, Draft Programmatic Environmental Impact Statement, Biscayne National...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

... DEPARTMENT OF THE INTERIOR National Park Service Coral Reef Restoration Plan, Draft Programmatic... Coral Reef Restoration Plan, Biscayne National Park. SUMMARY: Pursuant to the National Environmental... availability of a Draft Programmatic Environmental Impact Statement (DEIS) for the Coral Reef Restoration Plan...

78 FR 5403 - Fisheries of the Caribbean, Gulf, and South Atlantic; Aquaculture

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-25

...: Supplemental Notice of Intent (NOI) to prepare a supplement to the final programmatic environmental impact... programmatic environmental impact statement (PEIS) was published on September 12, 2008. On June 26, 2009, a... includes a final programmatic environmental impact statement (FPEIS), an initial regulatory flexibility...

7 CFR 25.623 - Programmatic changes.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Programmatic changes. 25.623 Section 25.623 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.623 Programmatic changes. Prior approval from USDA is required for all...

7 CFR 25.623 - Programmatic changes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Programmatic changes. 25.623 Section 25.623 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.623 Programmatic changes. Prior approval from USDA is required for all...

7 CFR 25.623 - Programmatic changes.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Programmatic changes. 25.623 Section 25.623 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.623 Programmatic changes. Prior approval from USDA is required for all...

7 CFR 25.623 - Programmatic changes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Programmatic changes. 25.623 Section 25.623 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.623 Programmatic changes. Prior approval from USDA is required for all...

7 CFR 25.623 - Programmatic changes.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Programmatic changes. 25.623 Section 25.623 Agriculture Office of the Secretary of Agriculture RURAL EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES Round II and Round IIS Grants § 25.623 Programmatic changes. Prior approval from USDA is required for all...

Toward Large-Area Sub-Arcsecond X-Ray Telescopes II

NASA Technical Reports Server (NTRS)

O'Dell, Stephen L.; Allured, Ryan; Ames, Andrew O.; Biskach, Michael P.; Broadway David M.; Bruni, Ricardo J.; Burrows, David; Cao, Jian; Chalifoux, Brandon D.; Chan, Kai-Wing;

Do peritraumatic emotions differentially predict PTSD symptom clusters? Initial evidence for emotion specificity.

PubMed

Dewey, Daniel; Schuldberg, David; Madathil, Renee

2014-08-01

This study investigated whether specific peritraumatic emotions differentially predict PTSD symptom clusters in individuals who have experienced stressful life events. Hypotheses were developed based on the SPAARS model of PTSD. It was predicted that the peritraumatic emotions of anger, disgust, guilt, and fear would significantly predict re-experiencing and avoidance symptoms, while only fear would predict hyperarousal. Undergraduate students (N = 144) participated in this study by completing a packet of self-report questionnaires. Multiple regression analyses were conducted with PCL-S symptom cluster scores as dependent variables and peritraumatic fear, guilt, anger, shame, and disgust as predictor variables. As hypothesized, peritraumatic anger, guilt, and fear all significantly predicted re-experiencing. However, only fear predicted avoidance, and anger significantly predicted hyperarousal. Results are discussed in relation to the theoretical role of emotions in the etiology of PTSD following the experience of a stressful life event.

Perceptions of Information Technology Specialists Regarding Securing Re-Employment after Offshoring Displacement

ERIC Educational Resources Information Center

Gallaway, Ricky A.

2015-01-01

The purpose of this qualitative exploratory case study was to explore why some IT specialists, after experiencing unemployment because of corporate offshoring, acquired gainful re-employment, whereas other similarly unemployed IT specialists had not. To effectively address this case study, two cases were studied: (a) displaced IT specialists who…

78 FR 4135 - Programmatic Environmental Impact Statement for the Training Mission and Mission Support...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-18

... DEPARTMENT OF DEFENSE Department of the Army Programmatic Environmental Impact Statement for the... Programmatic Environmental Impact Statement (PEIS) to evaluate the impacts of current and future training and... (NEPA) to evaluate the environmental impacts of proposed alternatives for implementing the training and...

32 CFR 651.27 - Programmatic NEPA analyses.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Programmatic NEPA analyses. 651.27 Section 651.27 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) ENVIRONMENTAL QUALITY ENVIRONMENTAL ANALYSIS OF ARMY ACTIONS (AR 200-2) Records and Documents § 651.27 Programmatic NEPA analyses...

76 FR 61120 - Notice of Intent To Prepare a Programmatic Environmental Assessment for Proposed Network...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-03

... POSTAL SERVICE Notice of Intent To Prepare a Programmatic Environmental Assessment for Proposed... of intent to prepare a Programmatic Environmental Assessment; Notice of Public Scoping Period. SUMMARY: To comply with the requirements of the National Environmental Policy Act (NEPA), the Postal...

78 FR 23926 - Extension of the Public Comment Period for the Draft Uranium Leasing Program Programmatic...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-23

... DEPARTMENT OF ENERGY Extension of the Public Comment Period for the Draft Uranium Leasing Program Programmatic Environmental Impact Statement AGENCY: Department of Energy. ACTION: Extension of the public... the Draft Uranium Leasing Program Programmatic Environmental Impact Statement (Draft ULP PEIS, DOE/EIS...

76 FR 77244 - Renewal of Information Collection; OMB Control Number 1040-0001, DOI Programmatic Clearance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... Number 1040-0001, DOI Programmatic Clearance for Customer Satisfaction Surveys AGENCY: Department of [email protected] . Reference ``DOI Programmatic Clearance for Customer Satisfaction Surveys'' in your email... public accountability by promoting a new focus on results, service quality, and customer satisfaction...

Parity modifies endocrine hormones in urine and problem-solving strategies of captive owl monkeys (Aotus spp.).

PubMed

Bardi, Massimo; Eckles, Meredith; Kirk, Emily; Landis, Timothy; Evans, Sian; Lambert, Kelly G

2014-12-01

Parental behavior modifies neural, physiologic, and behavioral characteristics of both maternal and paternal mammals. These parenting-induced modifications extend to brain regions not typically associated with parental responses themselves but that enhance ancillary responses, such as foraging efficiency and predator avoidance. Here we hypothesized that male and female owl monkeys (Aotus spp.) with reproductive experience (RE) would demonstrate more adaptive ancillary behavioral and neuroendocrine responses than those of their nonRE counterparts. To assess cognitive skills and coping flexibility, we introduced a foraging strategy task, including a set of novel objects (coin holders) marked with different symbols representing different food rewards, to the animals. To assess endocrine responses, urine samples were assayed for cortisol and dehydroepiandrosterone (DHEA) levels and their ratios to determine physiologic measures of emotional regulation in RE and nonRE owl monkeys. Compared with nonRE monkeys, experienced parents had higher DHEA:cortisol ratios after exposure to habituation training and on the first day of testing in the foraging task. Both hormones play critical roles in the stress response and coping mechanisms, and a high DHEA:cortisol ratio usually indicates increased coping skills. In addition, RE monkeys exhibited more efficient foraging responses (by 4-fold) than did the nonRE mating pairs. We conclude that RE modifies relevant behavioral and hormonal responses of both maternal and paternal owl monkeys exposed to a challenging cognitive paradigm. Corroborating previous research demonstrating adaptive modifications in foraging efficiency and emotional responses in reproductively experienced rodents, the current results extend these findings to a monogamous primate species.

Parity Modifies Endocrine Hormones in Urine and Problem-Solving Strategies of Captive Owl Monkeys (Aotus spp.)

PubMed Central

Eckles, Meredith; Kirk, Emily; Landis, Timothy; Evans, Sian; Lambert, Kelly G

2014-01-01

Parental behavior modifies neural, physiologic, and behavioral characteristics of both maternal and paternal mammals. These parenting-induced modifications extend to brain regions not typically associated with parental responses themselves but that enhance ancillary responses, such as foraging efficiency and predator avoidance. Here we hypothesized that male and female owl monkeys (Aotus spp.) with reproductive experience (RE) would demonstrate more adaptive ancillary behavioral and neuroendocrine responses than those of their nonRE counterparts. To assess cognitive skills and coping flexibility, we introduced a foraging strategy task, including a set of novel objects (coin holders) marked with different symbols representing different food rewards, to the animals. To assess endocrine responses, urine samples were assayed for cortisol and dehydroepiandrosterone (DHEA) levels and their ratios to determine physiologic measures of emotional regulation in RE and nonRE owl monkeys. Compared with nonRE monkeys, experienced parents had higher DHEA:cortisol ratios after exposure to habituation training and on the first day of testing in the foraging task. Both hormones play critical roles in the stress response and coping mechanisms, and a high DHEA:cortisol ratio usually indicates increased coping skills. In addition, RE monkeys exhibited more efficient foraging responses (by 4-fold) than did the nonRE mating pairs. We conclude that RE modifies relevant behavioral and hormonal responses of both maternal and paternal owl monkeys exposed to a challenging cognitive paradigm. Corroborating previous research demonstrating adaptive modifications in foraging efficiency and emotional responses in reproductively experienced rodents, the current results extend these findings to a monogamous primate species. PMID:25527030

Missile Defense Agency Ballistic Missile Defense System (BMDS): Programmatic Environmental Impact Statement. Volume 3 Appendices K - N

DTIC Science & Technology

2007-01-01

Bering Sea through direct affects on the fish, as well as the thousands of people dependent upon the fish for their nutrition , health, and economy...Newfoundland to British Columbia; however, the width of the migratory path narrows to 400 miles from east-west at the latitude of the Yucatan . (Lincoln et

A Pedagogy of Critical and Cultural Empowerment: What We Talk about in Graduate Teaching Seminars.

ERIC Educational Resources Information Center

Smith, Philip E., II

For the past five years it has been an ongoing programmatic concern at the University of Pittsburgh to provide a location in the graduate curriculum for discussion of professional and pedagogical issues that relate directly to the teaching, writing, and research projects of the teaching assistants and teaching fellows. The program was constituted…

An investigation on the tribological properties of Co(ReO4)2/MoS2 composite as potential lubricating additive at various temperatures

NASA Astrophysics Data System (ADS)

Wang, Junhai; Lu, Bing; Zhang, Lixiu; Li, Ting; Yan, Tingting; Li, Mengxu

2018-02-01

The Co(ReO4)2 powder was fabricated via the aqueous solution method, and mixed with MoS2 powder using ball milling technique. A certain concentration of Co(ReO4)2/MoS2 composite additive was dispersed into the poly alpha olefin base oil with the assistance of surface active agents. The load-carrying property and lubricating behavior of base oil containing a certain content of Co(ReO4)2/MoS2 composite additive at various temperatures were evaluated by four-ball test and ball-on-disc sliding friction test. The physical properties and friction-reducing mechanism of synthesized composite were ascertained by a series of characterization techniques including X-ray diffraction, scanning electron microscopy-energy dispersive spectroscopy, X-ray photoelectron spectroscopy, and differential thermal analysis/thermogravimetry. The four-ball test results suggested the Co(ReO4)2/MoS2 composite additive could effectively promote the load-carrying capacity of base oil, and decrease the friction coefficient as well as wear scar diameter. Ball-on-disc sliding friction test results showed that the base oil with Co(ReO4)2/MoS2 composite additive possessed lower friction coefficients than that of base oil in the whole temperature range, particularly at high temperatures. The protective layer consisted of composite additive and native oxides from superalloy substrate formed on the worn surface to prevent the direct contact between friction pair. The Co(ReO4)2/MoS2 composite played a dominant role in friction-reducing function in the protective layer at elevated temperatures, and the reason for this was that MoS2 possessed layered structure and superior adsorption capacity, and Co(ReO4)2 had experienced thermal softening with elevated temperatures and maintained shear-susceptible hexagonal structure.

Re-development of mental health first aid guidelines for suicidal ideation and behaviour: a Delphi study.

PubMed

Ross, Anna M; Kelly, Claire M; Jorm, Anthony F

2014-09-13

Suicide continues to be a leading cause of death globally. Friends and family are considered best positioned to provide initial assistance if someone is suicidal. Expert consensus guidelines on how to do this were published in 2008. Re-developing these guidelines is necessary to ensure they contain the most current recommended helping actions and remain consistent with the suicide prevention literature. The Delphi consensus method was used to determine the importance of including helping statements in the guidelines. These statements describe helping actions a member of the public can take, and information they should have, to help someone who is experiencing suicidal thoughts. Systematic searches of the available suicide prevention literature were carried out to find helping statements. Two expert panels, comprising 41 suicide prevention professionals and 35 consumer advocates respectively, rated each statement. Statements were accepted for inclusion in the guidelines if they were endorsed by at least 80% of each panel. Out of 436 statements, 164 were endorsed as appropriate helping actions in providing assistance to someone experiencing suicidal thoughts or engaging in suicidal behaviour. These statements were used to form the re-developed guidelines. The re-development of the guidelines has resulted in more comprehensive guidance than the earlier version, with the endorsement of 164 helping actions, compared to 30 previously. These guidelines will form the basis of a suicide prevention course aimed at educating members of the public on providing first aid to someone who is experiencing suicidal thoughts.

The Nature of Integration among PCK Components: A Case Study of Two Experienced Chemistry Teachers

ERIC Educational Resources Information Center

Aydin, Sevgi; Boz, Yezdan

2013-01-01

In this qualitative case study, we examined the nature of integration among pedagogical content knowledge (PCK) components. To attain the goal, two experienced chemistry teachers' teaching redox reactions and electrochemical cells was observed. The data were collected through card-sorting activity, content representation (CoRe) tool, observation,…

Partners’ Attributions for Service Members’ Symptoms of Combat-Related Posttraumatic Stress Disorder

PubMed Central

Renshaw, Keith D.; Allen, Elizabeth S.; Carter, Sarah P.; Markman, Howard J.; Stanley, Scott M.

2014-01-01

The association of service members’ combat-related PTSD with partners’ distress is weaker when spouses/partners believe that service members experienced more traumatic events during deployment. Also, when simultaneously examining partners’ perceptions of all PTSD symptoms, perceptions of re-experiencing symptoms (the symptoms most obviously connected to traumatic events) are significantly, negatively related to distress in partners. These findings are consistent with the notion that partners may be less distressed if they make external, rather than internal, attributions for service members’ symptoms. The present study explicitly tests this possibility. Civilian wives of active duty service members completed measures regarding their own marital satisfaction, their perceptions of service members’ combat exposure during deployments, their perceptions of service members’ symptoms of PTSD, and their attributions for those symptoms. External attributions were significantly, positively associated with perceptions of combat exposure (rp = .31) and re-experiencing symptoms (β = .33) and significantly, negatively associated with perceptions of numbing/withdrawal symptoms (rp = −.22). In contrast, internal attributions were significantly, negatively associated with perceptions of re-experiencing symptoms (β = −.18) and significantly, positively associated with perceptions of numbing/withdrawal symptoms (β = .46). Internal attributions significantly moderated the negative association of PTSD symptoms with marital satisfaction, such that the association strengthened as internal attributions increased. These findings are the first explicit support for an attributional understanding of distress in partners of combat veterans. Interventions that alter partners’ attributions may improve marital functioning. PMID:24491194

32 CFR 37.900 - May I tell a participant that information in financial and programmatic reports will not be...

Code of Federal Regulations, 2010 CFR

2010-07-01

... financial and programmatic reports will not be publicly disclosed? 37.900 Section 37.900 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Related to Other Administrative Matters Financial and Programmatic...

10 CFR 1021.330 - Programmatic (including site-wide) NEPA documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... prepare a programmatic EIS or EA (40 CFR 1502.4). DOE may also prepare a programmatic EIS or EA at any... Analysis, DOE shall determine whether the existing EIS remains adequate or whether to prepare a new site-wide EIS or supplement the existing EIS, as appropriate. The determination and supporting analysis...

75 FR 22589 - Cordova Electric Cooperative, Inc.; Notice of Proposed Restricted Service List for a Programmatic...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the... a programmatic agreement for managing properties included in, or eligible for inclusion in, the... person on the official service list for the above-captioned proceeding may request inclusion on the...

78 FR 11632 - Notice of Availability for the Draft Finding of No Significant Impact and Final Programmatic...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-19

... Significant Impact and Final Programmatic Environmental Assessment for Army 2020 Force Structure Realignment... Significant Impact (FNSI) and final Programmatic Environmental Assessment (PEA) for Army 2020 force structure realignments that may occur from Fiscal Years (FYs) 2013-2020. The Army published the Notice of Availability of...

Spacelab Level 4 programmatic Implementation Assessment Study. Volume 3: Optimization and programmatics

NASA Technical Reports Server (NTRS)

1978-01-01

Alternate level 4 integration approaches were synthesized and evaluated to establish the most cost effective experiment integration approach. Program baseline system trade studies are described, as well as Spacelab equipment utilization. Programmatic analysis of the baseline program was evaluated; the 2/3 and 1/3 traffic models were also considered.

Programmatic and teaching initiatives for ethnically diverse nursing students: a literature review.

PubMed

Torregosa, Marivic B; Morin, Karen H

2012-06-01

The purpose of this study was to examine the evidence of programmatic and teaching initiatives implemented by nursing faculty to enhance the academic success rates of ethnically diverse students (EDS). A search of the literature in the Cumulative Index to Nursing and Allied Health Literature and MEDLINE databases, wherein primary sources about programmatic and teaching initiative to promote academic success among EDS, was conducted. Using specific the Cumulative Index to Nursing and Allied Health Literature subject headings and Medical Subject Headings, 230 articles were retrieved from both databases. A total of 22 peer-reviewed articles published between 2000 and 2011 were included in the literature review. We found that evidence on the predominant programmatic and teaching initiatives for EDS academic success was inconclusive. The most common programmatic and teaching initiatives implemented by nursing faculty were peer mentoring, faculty-student mentoring, social networking, academic support, and financial support. Although positive student outcomes were reported about programmatic and teaching initiatives for EDS, the evidence remained inconclusive. Recommendations for policy and future research in this area of nursing education research were provided. Copyright © 2012. Published by Elsevier B.V.

Zero-gravity atmospheric Cloud Physics Experiment Laboratory; Programmatics report

NASA Technical Reports Server (NTRS)

1974-01-01

The programmatics effort included comprehensive analyses in four major areas: (1) work breakdown structure, (2) schedules, (3) costs, and (4) supporting research and technology. These analyses are discussed in detail in the following sections which identify and define the laboratory project development schedule, cost estimates, funding distributions and supporting research and technology requirements. All programmatics analyses are correlated among themselves and with the technical analyses by means of the work breakdown structure which serves as a common framework for program definition. In addition, the programmatic analyses reflect the results of analyses and plans for reliability, safety, test, and maintenance and refurbishment.

Implementation of Programmatic Quality and the Impact on Safety

NASA Astrophysics Data System (ADS)

Huls, Dale T.; Meehan, Kevin M.

2005-12-01

The implementation of an inadequate programmatic quality assurance discipline has the potential to adversely affect safety and mission success. This is best demonstrated in the lessons provided by the Apollo 1 Apollo 13 Challenger, and Columbia accidents; NASA Safety and Mission Assurance (S&MA) benchmarking exchanges; and conclusions reached by the Shuttle Return-to-Flight Task Group established following the Columbia Shuttle accident. Examples from the ISS Program demonstrate continuing issues with programmatic quality. Failure to adequately address programmatic quality assurance issues has a real potential to lead to continued inefficiency, increases in program costs, and additional catastrophic accidents.

Pi-CO₂ aqueous post-combustion CO₂ capture: Proof of concept through thermodynamic, hydrodynamic, and gas-lift pump modeling

DOE PAGES

Blount, G.; Gorensek, M.; Hamm, L.; ...

2014-12-31

Partnering in Innovation, Inc. (Pi-Innovation) introduces an aqueous post-combustion carbon dioxide (CO₂) capture system (Pi-CO₂) that offers high market value by directly addressing the primary constraints limiting beneficial re-use markets (lowering parasitic energy costs, reducing delivered cost of capture, eliminating the need for special solvents, etc.). A highly experienced team has completed initial design, modeling, manufacturing verification, and financial analysis for commercial market entry. Coupled thermodynamic and thermal-hydraulic mass transfer modeling results fully support proof of concept. Pi-CO₂ has the potential to lower total cost and risk to levels sufficient to stimulate global demand for CO₂ from local industrial sources.

"Re"storying the Present by "Re"visiting the Past: Unexpected Moments of Discovery and Illumination through Museum Learning

ERIC Educational Resources Information Center

Kawalilak, Colleen; Groen, Janet

2016-01-01

Two adult educators, guided by autoethnography as methodology, share the restorying of their own lifelong learning narratives and unexpected insights gained from having experienced the powerful potential of museum learning and culture. Having previously regarded museum visits as an experience that primarily tapped the intellectual, cognitive…

Laboratory Directed Research and Development FY-10 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dena Tomchak

2011-03-01

The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

1996 Laboratory directed research and development annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, C.E.; Harvey, C.L.; Lopez-Andreas, L.M.

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 1996. In addition to a programmatic and financial overview, the report includes progress reports from 259 individual R&D projects in seventeen categories. The general areas of research include: engineered processes and materials; computational and information sciences; microelectronics and photonics; engineering sciences; pulsed power; advanced manufacturing technologies; biomedical engineering; energy and environmental science and technology; advanced information technologies; counterproliferation; advanced transportation; national security technology; electronics technologies; idea exploration and exploitation; production; and science at the interfaces - engineering with atoms.

25 CFR 900.65 - What programmatic reports and data shall the Indian tribe or tribal organization provide?

Code of Federal Regulations, 2011 CFR

2011-04-01

... organization shall negotiate with the Secretary the type and frequency of program narrative and program data... 25 Indians 2 2011-04-01 2011-04-01 false What programmatic reports and data shall the Indian tribe... INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Programmatic Reports and Data Requirements § 900...

25 CFR 900.65 - What programmatic reports and data shall the Indian tribe or tribal organization provide?

Code of Federal Regulations, 2012 CFR

2012-04-01

... organization shall negotiate with the Secretary the type and frequency of program narrative and program data... 25 Indians 2 2012-04-01 2012-04-01 false What programmatic reports and data shall the Indian tribe... INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Programmatic Reports and Data Requirements § 900...

25 CFR 900.65 - What programmatic reports and data shall the Indian tribe or tribal organization provide?

Code of Federal Regulations, 2010 CFR

2010-04-01

... organization shall negotiate with the Secretary the type and frequency of program narrative and program data... 25 Indians 2 2010-04-01 2010-04-01 false What programmatic reports and data shall the Indian tribe... INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Programmatic Reports and Data Requirements § 900...

The Tips, Tricks, and Challenges of Teaching Undergraduate Kinesiology Students Research Methodology through a Programmatic Lens

ERIC Educational Resources Information Center

Beller, Jennifer M.

2013-01-01

This article describes a programmatic approach to undergraduate research (UGR) at Washington State University. In a programmatic approach, UGR is woven throughout the curriculum, with the expressed intent of producing undergraduate students who have at least a moderate ability to read, use, conduct, and present research. Washington State…

77 FR 5833 - Notice of Availability of the Draft Programmatic Environmental Impact Statement for Allocation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-06

... of the Draft Programmatic Environmental Impact Statement for Allocation of Oil Shale and Tar Sands... of Oil Shale and Tar Sands Resources on Lands Administered by the BLM in Colorado, Utah, and Wyoming... preferred method of commenting. Mail: Addressed to: Oil Shale and Tar Sands Resources Draft Programmatic EIS...

COMMUNITY COLLEGE RE-ENROLLMENT AFTER HURRICANE KATRINA

PubMed Central

LOWE, SARAH R.; RHODES, JEAN E.

2013-01-01

In this study, we explored predictors of community college re-enrollment after Hurricane Katrina among a sample of low-income women (N = 221). It was predicted that participants’ pre-hurricane educational optimism would predict community college re-enrollment a year after the hurricane. The influence of various demographic and additional resources (e.g., social support, childcare, hours of employment, psychological well-being) was also explored. High levels of pre- and post-hurricane educational optimism were significant predictors of re-enrollment, as were lower post-hurricane psychological distress and fewer post-hurricane hours employed. In addition, experiencing a greater number of moves since the hurricane was a marginally significant predictor of post-hurricane re-enrollment. PMID:23457425

Ballistic Missile Defense Final Programmatic Environmental Impact Statement

DTIC Science & Technology

1994-10-01

included: the need for BMD; budget allocations; procedural problems related to NEPA; nuclear weapon dangers; arms reductions; and potential contravention...2-26 2.6.2 TECHNOLOGY ALTERNATIVES ........................... 2-26 2.6.2.1 Directed Energy Weapons ..................... 2-26 2.6.2.2 Nuclear ...national defense strategy of mutually assured destruction to keep conflicts from escalating beyond conventional warfare to nuclear war. In 1955, the

Review of the University of Alaska FY 1986 Operating and Capital Budgets. Submitted to the Governor and the Fourteenth Alaska State Legislature. Document No. 85-3.

ERIC Educational Resources Information Center

Alaska State Commission on Postsecondary Education, Juneau.

A review of the University of Alaska's operating and capital budget submission for fiscal year 1986 is presented, directed at the educational and programmatic impact of the budget request. Five recommendations endorsed by the Alaska Commission on Postsecondary Education are analyzed. Additional contents include: summary information for the…

Review of the University of Alaska FY 1985 Operating and Capital Budgets. Submitted to the Governor and the Thirteenth Alaska State Legislature.

ERIC Educational Resources Information Center

Alaska State Commission on Postsecondary Education, Juneau.

A review of the University of Alaska's operating and capital budget submission for fiscal year 1985 is presented. The review is directed at the educational and programmatic impact of the budget request. In addition, 11 recommendations endorsed by the Alaska Commission on Postsecondary Education are analyzed. Additional contents include: the…

Space station data system analysis/architecture study. Task 2: Options development, DR-5. Volume 3: Programmatic options

NASA Technical Reports Server (NTRS)

1985-01-01

Task 2 in the Space Station Data System (SSDS) Analysis/Architecture Study is the development of an information base that will support the conduct of trade studies and provide sufficient data to make design/programmatic decisions. This volume identifies the preferred options in the programmatic category and characterizes these options with respect to performance attributes, constraints, costs, and risks. The programmatic category includes methods used to administrate/manage the development, operation and maintenance of the SSDS. The specific areas discussed include standardization/commonality; systems management; and systems development, including hardware procurement, software development and system integration, test and verification.

Brain network disturbance related to posttraumatic stress and traumatic brain injury in veterans.

PubMed

Spielberg, Jeffrey M; McGlinchey, Regina E; Milberg, William P; Salat, David H

2015-08-01

Understanding the neural causes and consequences of posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) is a high research priority, given the high rates of associated disability and suicide. Despite remarkable progress in elucidating the brain mechanisms of PTSD and mTBI, a comprehensive understanding of these conditions at the level of brain networks has yet to be achieved. The present study sought to identify functional brain networks and topological properties (measures of network organization and function) related to current PTSD severity and mTBI. Graph theoretic tools were used to analyze resting-state functional magnetic resonance imaging data from 208 veterans of Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New Dawn, all of whom had experienced a traumatic event qualifying for PTSD criterion A. Analyses identified brain networks and topological network properties linked to current PTSD symptom severity, mTBI, and the interaction between PTSD and mTBI. Two brain networks were identified in which weaker connectivity was linked to higher PTSD re-experiencing symptoms, one of which was present only in veterans with comorbid mTBI. Re-experiencing was also linked to worse functional segregation (necessary for specialized processing) and diminished influence of key regions on the network, including the hippocampus. Findings of this study demonstrate that PTSD re-experiencing symptoms are linked to weakened connectivity in a network involved in providing contextual information. A similar relationship was found in a separate network typically engaged in the gating of working memory, but only in veterans with mTBI. Published by Elsevier Inc.

Space construction system analysis. Part 2: Cost and programmatics

NASA Technical Reports Server (NTRS)

Vonflue, F. W.; Cooper, W.

1980-01-01

Cost and programmatic elements of the space construction systems analysis study are discussed. The programmatic aspects of the ETVP program define a comprehensive plan for the development of a space platform, the construction system, and the space shuttle operations/logistics requirements. The cost analysis identified significant items of cost on ETVP development, ground, and flight segments, and detailed the items of space construction equipment and operations.

rTMS for PTSD: induced merciful oblivion or elimination of abnormal hypermnesia?

PubMed

Rossi, Simone; Cappa, Stefano F; Ulivelli, Monica; De Capua, Alberto; Bartalini, Sabina; Rossini, Paolo M

2006-01-01

Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms.

Salvage prostate re-irradiation using high-dose-rate brachytherapy or focal stereotactic body radiotherapy for local recurrence after definitive radiation therapy.

PubMed

Mbeutcha, Aurélie; Chauveinc, Laurent; Bondiau, Pierre-Yves; Chand, Marie-Eve; Durand, Matthieu; Chevallier, Daniel; Amiel, Jean; Kee, Daniel Lam Cham; Hannoun-Lévi, Jean-Michel

2017-03-09

Optimal management of locally recurrent prostate cancer after definitive radiation therapy is still challenging. With the development of highly accurate radiotherapy devices, prostate salvage re-irradiation might generate lower toxicity rates than classical salvage therapies. We retrospectively evaluated the toxicity and the feasibility of a prostate re-irradiation after definitive radiation therapy failure. Two modalities were investigated: high-dose-rate brachytherapy (HDRB) on whole prostate gland and focal stereotactic radiotherapy (SBRT) using CyberKnife® linac. Between 2011 and 2015, 28 patients with imaged and/or biopsy-proven intra-prostatic recurrence of cancer after definitive radiation therapy underwent a salvage re-irradiation using HDRB (n = 10) or focal SBRT (n = 18). The schedule of re-irradiation was 35 Gy in 5 fractions. Biological response (defined as post-salvage radiation PSA variation) and biochemical no-evidence of disease (bNED) were evaluated in the whole cohort. For patients who had a positive biological response after salvage radiation, biochemical recurrence (BCR) and survival after salvage radiotherapy were evaluated. Post-salvage toxicities were assessed according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.03 and were compared to baseline status. Within a median follow-up of 22.5 months (IQR = 8-42), 9 (90%) patients experienced a positive biological response after salvage HDRB and 5 (50%) remained bNED at the end of the follow-up. Among patients who initially responded to salvage HDRB, the BCR rate was 44.4% after a median interval of 19.5 months (IQR = 11.5-26). Only one patient experienced a transient grade 3 urinary complication. In the SBRT group, the median follow-up was 14.5 months (IQR = 7-23) and 10 (55.6%) out of the 18 patients remained bNED. Among the 15 patients who initially responded to salvage SBRT, 5 (33.3%) experienced a BCR. One patient experienced a transient grade 4 urinary complication. At the end of the follow-up, all evaluated patients had a urinary status grade variation ≤ +1 grade. No grade 3-4 digestive toxicity was observed. Salvage prostate re-irradiation for locally recurrent cancer is feasible and generate low toxicities rates when using with HDRB or focal SBRT. However, further investigations are necessary to confirm these findings and to determine predictive features for patients who might benefit from such an approach.

Addressing the Barriers to Agile Development in the Department of Defense: Program Structure, Requirements, and Contracting

DTIC Science & Technology

2015-04-30

approach directly contrast with the traditional DoD acquisition model designed for a single big-bang waterfall approach (Broadus, 2013). Currently...progress, reduce technical and programmatic risk, and respond to feedback and changes more quickly than traditional waterfall methods (Modigliani...requirements, and contracting. The DoD can address these barriers by utilizing a proactively tailored Agile acquisition model , implementing an IT Box

Determining the Value of Future Information

DTIC Science & Technology

2011-03-01

trouble spots around the world, help plan military operations, and monitor the environment. The NRO’s Operational Support Office ( OSO ) “orchestrates...offices” (Parnell, Bennet, Engelbrecht, Szafranski, 2002:77). Parnell’s team’s research was intended “to help the OSO to identify and develop high- value...tasks that directly support OSO and NRO strategic objectives and to select the best portfolio of tasks to meet resource and programmatic constraints

Terminating DNA Tile Assembly with Nanostructured Caps.

PubMed

Agrawal, Deepak K; Jiang, Ruoyu; Reinhart, Seth; Mohammed, Abdul M; Jorgenson, Tyler D; Schulman, Rebecca

2017-10-24

Precise control over the nucleation, growth, and termination of self-assembly processes is a fundamental tool for controlling product yield and assembly dynamics. Mechanisms for altering these processes programmatically could allow the use of simple components to self-assemble complex final products or to design processes allowing for dynamic assembly or reconfiguration. Here we use DNA tile self-assembly to develop general design principles for building complexes that can bind to a growing biomolecular assembly and terminate its growth by systematically characterizing how different DNA origami nanostructures interact with the growing ends of DNA tile nanotubes. We find that nanostructures that present binding interfaces for all of the binding sites on a growing facet can bind selectively to growing ends and stop growth when these interfaces are presented on either a rigid or floppy scaffold. In contrast, nucleation of nanotubes requires the presentation of binding sites in an arrangement that matches the shape of the structure's facet. As a result, it is possible to build nanostructures that can terminate the growth of existing nanotubes but cannot nucleate a new structure. The resulting design principles for constructing structures that direct nucleation and termination of the growth of one-dimensional nanostructures can also serve as a starting point for programmatically directing two- and three-dimensional crystallization processes using nanostructure design.

Hepatitis C testing and re-testing among people attending sexual health services in Australia, and hepatitis C incidence among people with human immunodeficiency virus: analysis of national sentinel surveillance data.

PubMed

Boettiger, David C; Law, Matthew G; Dore, Gregory J; Guy, Rebecca; Callander, Denton; Donovan, Basil; O'Connor, Catherine C; Fairley, Christopher K; Hellard, Margaret; Matthews, Gail

2017-12-01

Direct acting antivirals are expected to drastically reduce the burden of hepatitis C virus (HCV) in people living with Human Immunodeficiency Virus (HIV). However, rates of HCV testing, re-testing and incident infection in this group remain uncertain in Australia. We assessed trends in HCV testing, re-testing and incident infection among HIV-positive individuals, and evaluated factors associated with HCV re-testing and incident infection. The study population consisted of HIV-positive individuals who visited a sexual health service involved in the Australian Collaboration for Coordinated Enhanced Sentinel Surveillance (ACCESS) between 2007 and 2015. Poisson regression was used to assess trends and to evaluate factors associated with HCV re-testing and incident HCV infection. There were 9227 HIV-positive individuals included in our testing rate analysis. Of 3799 HIV-positive/HCV-negative people that attended an ACCESS sexual health service more than once, 2079 (54.7%) were re-tested for HCV and were therefore eligible for our incidence analysis. The rate of HCV testing increased from 17.1 to 51.4 tests per 100 patient years between 2007 and 2015 (p for trend <0.01). Over the same period, HCV re-testing rates increased from 23.9 to 79.7 tests per 100 person years (p for trend <0.01). A clear increase in testing and re-testing began after 2011. Patients who identified as men who have sex with men and those with a history of injecting drug use experienced high rates of HCV re-testing over the course of the study period. Among those who re-tested, 157 incident HCV infections occurred at a rate of 2.5 events per 100 person years. Between 2007 and 2009, 2010-2011, 2012-2013 and 2014-2015, rates of incident HCV were 0.8, 1.5, 3.9 and 2.7 events per 100 person years, respectively (p for trend <0.01). Incident HCV was strongly associated with a history of injecting drug use. High rates of HCV testing and re-testing among HIV-positive individuals in Australia will assist strategies to achieve HCV elimination through rapid treatment scale up. Continued monitoring of HCV incidence in this population is essential for guiding both HCV prevention and treatment strategies.

Comprehensive facilities plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-09-01

The Ernest Orlando Lawrence Berkeley National Laboratory`s Comprehensive Facilities Plan (CFP) document provides analysis and policy guidance for the effective use and orderly future development of land and capital assets at the Berkeley Lab site. The CFP directly supports Berkeley Lab`s role as a multiprogram national laboratory operated by the University of California (UC) for the Department of Energy (DOE). The CFP is revised annually on Berkeley Lab`s Facilities Planning Website. Major revisions are consistent with DOE policy and review guidance. Facilities planing is motivated by the need to develop facilities for DOE programmatic needs; to maintain, replace and rehabilitatemore » existing obsolete facilities; to identify sites for anticipated programmatic growth; and to establish a planning framework in recognition of site amenities and the surrounding community. The CFP presents a concise expression of the policy for the future physical development of the Laboratory, based upon anticipated operational needs of research programs and the environmental setting. It is a product of the ongoing planning processes and is a dynamic information source.« less

Managing Programmatic Risk for Complex Space System Developments

NASA Technical Reports Server (NTRS)

Panetta, Peter V.; Hastings, Daniel; Brumfield, Mark (Technical Monitor)

2001-01-01

Risk management strategies have become a recent important research topic to many aerospace organizations as they prepare to develop the revolutionary complex space systems of the future. Future multi-disciplinary complex space systems will make it absolutely essential for organizations to practice a rigorous, comprehensive risk management process, emphasizing thorough systems engineering principles to succeed. Project managers must possess strong leadership skills to direct high quality, cross-disciplinary teams for successfully developing revolutionary space systems that are ever increasing in complexity. Proactive efforts to reduce or eliminate risk throughout a project's lifecycle ideally must be practiced by all technical members in the organization. This paper discusses some of the risk management perspectives that were collected from senior managers and project managers of aerospace and aeronautical organizations by the use of interviews and surveys. Some of the programmatic risks which drive the success or failure of projects are revealed. Key findings lead to a number of insights for organizations to consider for proactively approaching the risks which face current and future complex space systems projects.

Engineering research, development and technology report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Langland, R T

1999-02-01

Nineteen ninety-eight has been a transition year for Engineering, as we have moved from our traditional focus on thrust areas to a more focused approach with research centers. These five new centers of excellence collectively comprise Engineering's Science and Technology program. This publication summarizes our formative year under this new structure. Let me start by talking about the differences between a thrust area and a research center. The thrust area is more informal, combining an important technology with programmatic priorities. In contrast, a research center is directly linked to an Engineering core technology. It is the purer model, for itmore » is more enduring yet has the scope to be able to adapt quickly to evolving programmatic priorities. To put it another way, the mission of a thrust area was often to grow the programs in conjunction with a technology, whereas the task of a research center is to vigorously grow our core technologies. By cultivating each core technology, we in turn enable long-term growth of new programs.« less

Psychological Intimate Partner Violence and Sexual Risk Behavior: Examining the Role of Distinct PTSD Symptoms in the Partner Violence-sexual Risk Link

PubMed Central

Overstreet, Nicole M.; Willie, Tiara C.; Hellmuth, Julianne C.; Sullivan, Tami P.

2014-01-01

BACKGROUND Research has examined how physical and sexual intimate partner violence (IPV) victimization increases sexual risk behavior, yet research is lacking on 1) the effect of psychological IPV on sexual risk behavior and 2) factors through which psychological IPV may be linked to sexual risk behavior. METHODS The current study examined the relationship between psychological IPV and sexual risk behavior controlling for other forms of IPV (i.e., physical and sexual) in a sample of 186 HIV-negative community women currently experiencing IPV. Further, this study examined the potential mediating effects of four posttraumatic stress disorder (PTSD) symptom severity clusters (i.e., re-experiencing, avoidance, numbing, and hyperarousal) on this relationship. FINDINGS Results revealed that greater severity of psychological IPV was uniquely and directly related to greater sexual risk behavior. Additionally, of the four PTSD symptom severity clusters, only avoidance symptom severity mediated the relationship between psychological IPV and sexual risk behavior. CONCLUSION Implications for addressing psychological IPV and PTSD to improve women’s sexual health outcomes are discussed. PMID:25498762

Weathering patterns of polycyclic aromatic hydrocarbons contained in submerged Deepwater Horizon oil spill residues when re-exposed to sunlight.

PubMed

John, Gerald F; Han, Yuling; Clement, T Prabhakar

2016-12-15

The Deepwater Horizon (DWH) oil spill event released a large amount of sweet crude oil into the Gulf of Mexico (GOM). An unknown portion of this oil that arrived along the Alabama shoreline interacted with nearshore sediments and sank forming submerged oil mats (SOMs). A considerable amount of hydrocarbons, including polycyclic aromatic hydrocarbons (PAHs), were trapped within these buried SOMs. Recent studies completed using the oil spill residues collected along the Alabama shoreline have shown that several PAHs, especially higher molecular weight PAHs (four or more aromatic rings), are slowly weathering compared to the weathering levels experienced by the oil when it was floating over the GOM. In this study we have hypothesized that the weathering rates of PAHs in SOMs have slowed down because the buried oil was isolated from direct exposure to sunlight, thus hindering the photodegradation pathway. We further hypothesized that re-exposing SOMs to sunlight can reactivate various weathering reactions. Also, SOMs contain 75-95% sand (by weight) and the entrapped sand could either block direct sunlight or form large oil agglomerates with very little exposed surface area; these processes could possibly interfere with weathering reactions. To test these hypotheses, we completed controlled experiments to study the weathering patterns of PAHs in a field recovered SOM sample after re-exposing it to sunlight. Our experimental results show that the weathering levels of several higher molecular weight PAHs have slowed down primarily due to the absence of sunlight-induced photodegradation reactions. The data also show that sand particles in SOM material could potentially interfere with photodegradation reactions. Copyright © 2016 Elsevier B.V. All rights reserved.

Vicarious stress: patterns of disturbance and use of mental health services by those indirectly affected by the Oklahoma City bombing.

PubMed

Sprang, G

2001-10-01

This study explored the intermediate psychological effects of terrorism on adults not directly affected by the Oklahoma City bombing by examining the course of PTSD and subthreshold PTSD symptoms over time and whether treatment affected this course. The respondents were interviewed at 3-mo. intervals for 18 mo. following an initial 6-mo. survey. Analysis suggested avoidance, re-experiencing, and increased arousal symptoms in this population were limited over time, declining with or without treatment between 6 and 9 mo. Conversely, victimization symptoms remained high without mental health intervention for the first year after the disaster. The study also examined the nature and occurrence of comorbidity in groups seeking and not seeking treatment.

Predictors of homeless services re-entry within a sample of adults receiving Homelessness Prevention and Rapid Re-Housing Program (HPRP) assistance.

PubMed

Brown, Molly; Vaclavik, Danielle; Watson, Dennis P; Wilka, Eric

2017-05-01

Local and national evaluations of the federal Homelessness Prevention and Rapid Re-Housing Program (HPRP) have demonstrated a high rate of placement of program participants in permanent housing. However, there is a paucity of research on the long-term outcomes of HPRP, and research on rehousing and prevention interventions for single adults experiencing homelessness is particularly limited. Using Homeless Management Information System data from 2009 to 2015, this study examined risk of return to homeless services among 370 permanently housed and 71 nonpermanently housed single adult HPRP participants in Indianapolis, Indiana. Kaplan-Meier survival curves were conducted to analyze time-to-service re-entry for the full sample, and the homelessness prevention and rapid rehousing participants separately. With an average follow-up of 4.5 years after HPRP exit, 9.5% of the permanently housed HPRP participants and 16.9% of those nonpermanently housed returned to homeless services. By assistance type, 5.4% of permanently housed and 15.8% of nonpermanently housed homelessness prevention recipients re-entered services, and 12.8% of permanently housed and 18.2% of nonpermanently housed rapid rehousing recipients re-entered during the follow-up period. Overall, veterans, individuals receiving rapid rehousing services, and those whose income did not increase during HPRP had significantly greater risk of returning to homeless services. Veterans were at significantly greater risk of re-entry when prevention and rehousing were examined separately. Findings suggest a need for future controlled studies of prevention and rehousing interventions for single adults, aiming to identify unique service needs among veterans and those currently experiencing homelessness in need of rehousing to inform program refinement. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Management Approach for NASA's Earth Venture-1 (EV-1) Airborne Science Investigations

NASA Technical Reports Server (NTRS)

Guillory, Anthony R.; Denkins, Todd C.; Allen, B. Danette

2013-01-01

The Earth System Science Pathfinder (ESSP) Program Office (PO) is responsible for programmatic management of National Aeronautics and Space Administration's (NASA) Science Mission Directorate's (SMD) Earth Venture (EV) missions. EV is composed of both orbital and suborbital Earth science missions. The first of the Earth Venture missions is EV-1, which are Principal Investigator-led, temporally-sustained, suborbital (airborne) science investigations costcapped at $30M each over five years. Traditional orbital procedures, processes and standards used to manage previous ESSP missions, while effective, are disproportionally comprehensive for suborbital missions. Conversely, existing airborne practices are primarily intended for smaller, temporally shorter investigations, and traditionally managed directly by a program scientist as opposed to a program office such as ESSP. In 2010, ESSP crafted a management approach for the successful implementation of the EV-1 missions within the constructs of current governance models. NASA Research and Technology Program and Project Management Requirements form the foundation of the approach for EV-1. Additionally, requirements from other existing NASA Procedural Requirements (NPRs), systems engineering guidance and management handbooks were adapted to manage programmatic, technical, schedule, cost elements and risk. As the EV-1 missions are nearly at the end of their successful execution and project lifecycle and the submission deadline of the next mission proposals near, the ESSP PO is taking the lessons learned and updated the programmatic management approach for all future Earth Venture Suborbital (EVS) missions for an even more flexible and streamlined management approach.

Programmatic approaches to assessing and improving animal welfare in zoos and aquariums.

PubMed

Barber, Joseph C E

2009-11-01

There continues to be intense public, professional, and scientific focus on the welfare of animals in zoos and aquariums, but implementing welfare assessment tools consistently throughout this community remains challenging. Indirect measures can be used to assess "welfare potential"-the potential that animals will experience good welfare based on the care that they are provided with. Zoos and aquariums focus on welfare potential with their continued commitment to develop animal care guidelines (e.g. Animal Care Manuals) that can play a role within institutional accreditation or certification. The Association of Zoos and Aquariums Animal Welfare Committee has been pursuing approaches to maximize welfare potential by developing the concept of an integrated welfare approach or framework-an attempt to identify recommended animal care programs (e.g. enrichment, nutrition, veterinary care, research, and animal training programs) and their programmatic components. Objectively assessing the influence that animal care recommendations have on the welfare of individual animals is important to determine the efficacy of programmatic approaches. The future of welfare assessment within zoos and aquariums will include population-level evaluations-tracking emerging trends in health and behavior that come from both formal and informal institutional animal reports. Sharing this information, and performing meta-analyses of the data using epidemiological approaches, will become easier with advances in technology and database management software. Identifying welfare "red/green flags" throughout captive populations will provide direction for more focused assessments that will ultimately inform the design of more effective animal care programs.

Basic and Applied Materials Science Research Efforts at MSFC Germane to NASA Goals

NASA Technical Reports Server (NTRS)

2003-01-01

Presently, a number of investigations are ongoing that blend basic research with engineering applications in support of NASA goals. These include (1) "Pore Formation and Mobility (PFMI) " An ISS Glovebox Investigation" NASA Selected Project - 400-34-3D; (2) "Interactions Between Rotating Bodies" Center Director's Discretionary Fund (CDDF) Project - 279-62-00-16; (3) "Molybdenum - Rhenium (Mo-Re) Alloys for Nuclear Fuel Containment" TD Collaboration - 800-11-02; (4) "Fabrication of Alumina - Metal Composites for Propulsion Components" ED Collaboration - 090-50-10; (5) "Radiation Shielding for Deep-Space Missions" SD Effort; (6) "Other Research". In brief, "Pore Formation and Mobility" is an experiment to be conducted in the ISS Microgravity Science Glovebox that will systematically investigate the development, movement, and interactions of bubbles (porosity) during the controlled directional solidification of a transparent material. In addition to promoting our general knowledge of porosity physics, this work will serve as a guide to future ISS experiments utilizing metal alloys. "Interactions Between Rotating Bodies" is a CDDF sponsored project that is critically examining, through theory and experiment, claims of "new" physics relating to gravity modification and electric field effects. "Molybdenum - Rhenium Alloys for Nuclear Fuel Containment" is a TD collaboration in support of nuclear propulsion. Mo-Re alloys are being evaluated and developed for nuclear fuel containment. "Fabrication of Alumina - Metal Composites for Propulsion Components" is an ED collaboration with the intent of increasing strength and decreasing weight of metal engine components through the incorporation of nanometer-sized alumina fibers. "Radiation Shielding for Deep-Space Missions" is an SD effort aimed at minimizing the health risk from radiation to human space voyagers; work to date has been primarily programmatic but experiments to develop hydrogen-rich materials for shielding are planned. "Other Research" includes: BUNDLE (Bridgman Unidirectional Dendrite in a Liquid Experiment) activities (primarily crucible development), vibrational float-zone processing (with Vanderbilt University), use of ultrasonics in materials processing (with UAH), rotational effects on microstructural development, and application of magnetic fields for mixing.

Comparison of Combined Aerobic and High-Force Eccentric Resistance Exercise With Aerobic Exercise Only for People With Type 2 Diabetes Mellitus

PubMed Central

Marcus, Robin L; Smith, Sheldon; Morrell, Glen; Addison, Odessa; Dibble, Leland E; Wahoff-Stice, Donna; LaStayo, Paul C

2008-01-01

Background and Purpose: The purpose of this study was to compare the outcomes between a diabetes exercise training program using combined aerobic and high-force eccentric resistance exercise and a program of aerobic exercise only. Subjects and Methods: Fifteen participants with type 2 diabetes mellitus (T2DM) participated in a 16-week supervised exercise training program: 7 (mean age=50.7 years, SD=6.9) in a combined aerobic and eccentric resistance exercise program (AE/RE group) and 8 (mean age=58.5 years, SD=6.2) in a program of aerobic exercise only (AE group). Outcome measures included thigh lean tissue and intramuscular fat (IMF), glycosylated hemoglobin, body mass index (BMI), and 6-minute walk distance. Results: Both groups experienced decreases in mean glycosylated hemoglobin after training (AE/RE group: −0.59% [95% confidence interval (CI)=−1.5 to 0.28]; AE group: −0.31% [95% CI=−0.60 to −0.03]), with no significant between-group differences. There was an interaction between group and time with respect to change in thigh lean tissue cross-sectional area, with the AE/RE group gaining more lean tissue (AE/RE group: 15.1 cm2 [95% CI=7.6 to 22.5]; AE group: −5.6 cm2 [95% CI=−10.4 to 0.76]). Both groups experienced decreases in mean thigh IMF cross-sectional area (AE/RE group: −1.2 cm2 [95% CI=−2.6 to 0.26]; AE group: −2.2 cm2 [95% CI=−3.5 to −0.84]) and increases in 6-minute walk distance (AE/RE group: 45.5 m [95% CI=7.5 to 83.6]; AE group: 29.9 m [95% CI=−7.7 to 67.5]) after training, with no between-group differences. There was an interaction between group and time with respect to change in BMI, with the AE/RE group experiencing a greater decrease in BMI. Discussion and Conclusion: Significant improvements in long-term glycemic control, thigh composition, and physical performance were demonstrated in both groups after participating in a 16-week exercise program. Subjects in the AE/RE group demonstrated additional improvements in thigh lean tissue and BMI. Improvements in thigh lean tissue may be important in this population as a means to increase resting metabolic rate, protein reserve, exercise tolerance, and functional mobility. PMID:18801851

rTMS For PTSD: Induced Merciful Oblivion or Elimination of Abnormal Hypermnesia?

PubMed Central

Rossi, Simone; Cappa, Stefano F.; Ulivelli, Monica; De Capua, Alberto; Bartalini, Sabina; Rossini, Paolo M.

2006-01-01

Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms. PMID:17148840

Coal liquefaction processes and development requirements analysis for synthetic fuels production

NASA Technical Reports Server (NTRS)

1980-01-01

Focus of the study is on: (1) developing a technical and programmatic data base on direct and indirect liquefaction processes which have potential for commercialization during the 1980's and beyond, and (2) performing analyses to assess technology readiness and development trends, development requirements, commercial plant costs, and projected synthetic fuel costs. Numerous data sources and references were used as the basis for the analysis results and information presented.

Space station accommodations for life sciences research facilities: Phase A conceptual design and programmatics studies for Missions SAAX0307, SAAX0302 and the transition from SAAX0307 to SAAX0302. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1986-01-01

The conceptual designs and programmatics for a Space Station Nonhuman Life Sciences Research Facility (LSRF) are highlighted. Conceptual designs and programmatics encompass an Initial Orbital Capability (IOC) LSRF, a growth or Follow-on Orbital Capability (FOC), and the transitional process required to modify the IOC LSRF to the FOC LSRF.

An Investigation of the Re-Entry Adjustment of Indians Who Studied in the U.S.A. Occasional Papers in Intercultural Learning, Number 17.

ERIC Educational Resources Information Center

Hansel, Bettina

This study explored the readjustment experience of 49 Indians who came to the United States to study and then returned to their home country. Interviews revealed that most experienced some stress or difficulty after their re-entry, with problems ranging from initial anxiety about getting a job or shock at the crowded conditions, pollution, or the…

Analysis of microgravity space experiments Space Shuttle programmatic safety requirements

NASA Technical Reports Server (NTRS)

Terlep, Judith A.

1996-01-01

This report documents the results of an analysis of microgravity space experiments space shuttle programmatic safety requirements and recommends the creation of a Safety Compliance Data Package (SCDP) Template for both flight and ground processes. These templates detail the programmatic requirements necessary to produce a complete SCDP. The templates were developed from various NASA centers' requirement documents, previously written guidelines on safety data packages, and from personal experiences. The templates are included in the back as part of this report.

Direct and indirect light emissions from layered ReS2-x Se x (0 ≤ x ≤ 2)

NASA Astrophysics Data System (ADS)

Ho, Ching-Hwa; Liu, Zhan-Zhi; Lin, Min-Han

2017-06-01

ReS2 and ReSe2 have recently been enthusiastically studied owing to the specific in-plane electrical, optical and structural anisotropy caused by their distorted one-layer trigonal (1 T) phase, whereas other traditional transition-metal dichalcogenides (TMDCs, e.g. MoS2 and WSe2) have a hexagonal structure. Because of this special property, more and versatile nano-electronics and nano-optoelectronics devices can be developed. In this work, 2D materials in the series ReS2-x Se x (0 ≤ x ≤ 2) have been successfully grown by the method of chemical vapor transport. The direct and indirect resonant emissions of the complete series of layers can be simultaneously detected by polarized micro-photoluminescence (μPL) spectroscopy when the thickness of the ReS2-x Se x is greater than ˜70 nm. When it is less than 70 nm, only three direct excitonic emissions—E 1 ex, E 2 ex and E S ex—are detected. For the thick (bulk) ReS2-x Se x , more stacking of the ReX2 monolayers even flattens and shifts the valence-band maximum from Γ to the other K- or M-related points, thus leading to the coexistence of direct and indirect resonant light emissions from the c-plane ReX2. The transmittance absorption edge of each bulk ReX2 (a few microns thick) usually has a lower energy than those of the direct E 1 ex and E 2 ex excitonic emissions to form indirect absorption. The coexistence of direct and indirect emissions in ReX2 is a unique characteristic of a 2D layered semiconductor possessing triclinic low symmetry.

Impacts of fire exclusion and recent managed fire on forest structure in old growth Sierra Nevada mixed-conifer forests

Treesearch

Brandon M. Collins; Richard G. Everett; Scott L. Stephens

2011-01-01

We re-sampled areas included in an unbiased 1911 timber inventory conducted by the U.S. Forest Service over a 4000 ha study area. Over half of the re-sampled area burned in relatively recent management- and lightning-ignited fires. This allowed for comparisons of both areas that have experienced recent fire and areas with no recent fire, to the same areas historically...

Communicable disease control programmes and health systems: an analytical approach to sustainability.

PubMed

Shigayeva, Altynay; Coker, Richard J

2015-04-01

There is renewed concern over the sustainability of disease control programmes, and re-emergence of policy recommendations to integrate programmes with general health systems. However, the conceptualization of this issue has remarkably received little critical attention. Additionally, the study of programmatic sustainability presents methodological challenges. In this article, we propose a conceptual framework to support analyses of sustainability of communicable disease programmes. Through this work, we also aim to clarify a link between notions of integration and sustainability. As a part of development of the conceptual framework, we conducted a systematic literature review of peer-reviewed literature on concepts, definitions, analytical approaches and empirical studies on sustainability in health systems. Identified conceptual proposals for analysis of sustainability in health systems lack an explicit conceptualization of what a health system is. Drawing upon theoretical concepts originating in sustainability sciences and our review here, we conceptualize a communicable disease programme as a component of a health system which is viewed as a complex adaptive system. We propose five programmatic characteristics that may explain a potential for sustainability: leadership, capacity, interactions (notions of integration), flexibility/adaptability and performance. Though integration of elements of a programme with other system components is important, its role in sustainability is context specific and difficult to predict. The proposed framework might serve as a basis for further empirical evaluations in understanding complex interplay between programmes and broader health systems in the development of sustainable responses to communicable diseases. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2014; all rights reserved.

Considerations for Micro- and Nano-scale Space Payloads

NASA Technical Reports Server (NTRS)

Altemir, David A.

1995-01-01

This paper collects and summarizes many of the issues associated with the design, analysis, and flight of space payloads. However, highly miniaturized experimental packages are highly susceptible to the deleterious effects of induced contamination and charged particles when they are directly exposed to the space environment. These two problem areas are addressed and a general discussion of space environments, applicable design and analysis practices (with extensive references to the open literature) and programmatic considerations are presented.

Laboratory directed research and development annual report 2004.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2004. In addition to a programmatic and financial overview, the report includes progress reports from 352 individual R and D projects in 15 categories. The 15 categories are: (1) Advanced Concepts; (2) Advanced Manufacturing; (3) Biotechnology; (4) Chemical and Earth Sciences; (5) Computational and Information Sciences; (6) Differentiating Technologies; (7) Electronics and Photonics; (8) Emerging Threats; (9) Energy and Critical Infrastructures; (10) Engineering Sciences; (11) Grand Challenges; (12) Materials Science and Technology; (13) Nonproliferation and Materials Control; (14) Pulsed Power and High Energy Densitymore » Sciences; and (15) Corporate Objectives.« less

Laboratory Directed Research and Development 1998 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pam Hughes; Sheila Bennett eds.

1999-07-14

The Laboratory's Directed Research and Development (LDRD) program encourages the advancement of science and the development of major new technical capabilities from which future research and development will grow. Through LDRD funding, Pacific Northwest continually replenishes its inventory of ideas that have the potential to address major national needs. The LDRD program has enabled the Laboratory to bring to bear its scientific and technical capabilities on all of DOE's missions, particularly in the arena of environmental problems. Many of the concepts related to environmental cleanup originally developed with LDRD funds are now receiving programmatic support from DOE, LDRD-funded work inmore » atmospheric sciences is now being applied to DOE's Atmospheric Radiation Measurement Program. We also have used concepts initially explored through LDRD to develop several winning proposals in the Environmental Management Science Program. The success of our LDRD program is founded on good management practices that ensure funding is allocated and projects are conducted in compliance with DOE requirements. We thoroughly evaluate the LDRD proposals based on their scientific and technical merit, as well as their relevance to DOE's programmatic needs. After a proposal is funded, we assess progress annually using external peer reviews. This year, as in years past, the LDRD program has once again proven to be the major enabling vehicle for our staff to formulate new ideas, advance scientific capability, and develop potential applications for DOE's most significant challenges.« less

Fabry disease under enzyme replacement therapy-new insights in efficacy of different dosages.

PubMed

Krämer, Johannes; Lenders, Malte; Canaan-Kühl, Sima; Nordbeck, Peter; Üçeyler, Nurcan; Blaschke, Daniela; Duning, Thomas; Reiermann, Stefanie; Stypmann, Jörg; Brand, Stefan-Martin; Gottschling, Timo; Störk, Stefan; Wanner, Christoph; Sommer, Claudia; Brand, Eva; Weidemann, Frank

2017-11-23

Fabry patients on reduced dose of agalsidase-beta or after switch to agalsidase-alfa show a decline in estimated glomerular filtration rate (eGFR) and an increase of the Mainz Severity Score Index. In this prospective observational study, we assessed end-organ damage and clinical symptoms in 112 patients who had received agalsidase-beta (1.0 mg/kg) for >1 year, who were (i) non-randomly assigned to continue this treatment regime (regular-dose group, n = 37); (ii) received a reduced dose of agalsidase-beta and subsequent switch to agalsidase-alfa (0.2 mg/kg) or a direct switch to 0.2 mg/kg agalsidase-alfa (switch group, n = 38); or (iii) were re-switched to agalsidase-beta after receiving agalsidase-alfa for at least 12 months (re-switch group, n = 37) with a median follow-up of 53 (38-57) months. eGFR of patients in the regular-dose group remained stable. Patients in the switch group showed an annual eGFR loss of - 4.6  ±  9.1 mL/min/1.73 m2 (P < 0.05). Patients in the re-switch group also had an eGFR loss of - 2.2  ±  4.4 mL/min/1.73 m2 after re-switch to agalsidase-beta, but to a lower degree compared with the switch group (P < 0.05). Patients in the re-switch group suffered less frequently from diarrhoea (relative risk 0.42; 95% confidence interval 0.19-0.93; P = 0.02). Lyso-Gb3 remained stable in the switch (P = 0.97) and the regular-dose (P = 0.48) groups, but decreased in the re-switch group after change of the therapy regimen (P < 0.05). After switch to agalsidase-alfa, Fabry patients experienced a continuous decline in eGFR, while this decline was attenuated in patients who were re-switched to agalsidase-beta. Decreasing lyso-Gb3 levels may indicate a better treatment response in the latter group. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Benefits and costs of programmatic agreements

DOT National Transportation Integrated Search

2015-02-01

The performing organization, on behalf of the FHWA Office of Planning, Environment, and Realty, conducted a benefit-cost assessment of programmatic agreements and approaches. The assessment consisted of a case study approach that evaluated three agre...

76 FR 50249 - Notice of Extension of Public Comment Period for the Draft Environmental Impact Statement...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

... the Draft Environmental Impact Statement, Including a Draft Programmatic Agreement, for the Clark... Programmatic Agreement, for the Southern Nevada Water Authority's (SNWA) proposed Clark, Lincoln, and White...

A Review of 10 Years of Vasectomy Programming and Research in Low-Resource Settings.

PubMed

Shattuck, Dominick; Perry, Brian; Packer, Catherine; Chin Quee, Dawn

2016-12-23

Vasectomy is a highly effective and safe contraceptive method for couples who want to stop childbearing, but only 2.4% of men around the world use this method. We conducted an extensive review of the vasectomy research literature and programmatic reports, published between April 2005 and April 2015, to synthesize barriers and facilitators to vasectomy adoption. Of the more than 230 documents initially retrieved in our search, we ultimately included 75 documents in our review and synthesized the findings according to the Supply-Enabling Environment-Demand (SEED) Programming Model. Regarding promoting demand for vasectomy services, we found there was a general lack of awareness about the method among both men and women, which often fueled erroneous assumptions about how vasectomy affects men. Several types of programmatic activities directly addressed knowledge gaps and negative misperceptions, including community-based and mass media communications, employer-based promotion, and group counseling. For supply of services, the lack of or inaccurate knowledge about vasectomy was also prevalent among providers, particularly among community-based health workers. Programmatic activities to improve service delivery included the use of evidence-based vasectomy techniques such as no-scalpel vasectomy, whole-site trainings, task shifting, cascade training, and mobile outreach. Finally, programmatic approaches to building a more enabling environment included engagement of governments and other community and religious leaders as well as campaigns with gender transformative messaging that countered common myths and encouraged men's positive engagement in family planning and reproductive health. In summary, a successful vasectomy program is comprised of the mutually reinforcing components of continual demand for services and access to and supply of well-trained providers. In addition, there is an underlying need for enabling policies within the cultural and gender environments that extend beyond vasectomy and include men not just as default partners of female family planning clients but as equal beneficiaries of family planning and reproductive health programs in their own right. Accelerating progress toward meaningful integration of vasectomy into a comprehensive contraceptive method mix is only possible when political and financial will are aligned and support the logistical and promotional activities of a male reproductive health agenda. © Shattuck et al.

A Review of 10 Years of Vasectomy Programming and Research in Low-Resource Settings

PubMed Central

Shattuck, Dominick; Perry, Brian; Packer, Catherine; Chin Quee, Dawn

2016-01-01

ABSTRACT Vasectomy is a highly effective and safe contraceptive method for couples who want to stop childbearing, but only 2.4% of men around the world use this method. We conducted an extensive review of the vasectomy research literature and programmatic reports, published between April 2005 and April 2015, to synthesize barriers and facilitators to vasectomy adoption. Of the more than 230 documents initially retrieved in our search, we ultimately included 75 documents in our review and synthesized the findings according to the Supply–Enabling Environment–Demand (SEED) Programming Model. Regarding promoting demand for vasectomy services, we found there was a general lack of awareness about the method among both men and women, which often fueled erroneous assumptions about how vasectomy affects men. Several types of programmatic activities directly addressed knowledge gaps and negative misperceptions, including community-based and mass media communications, employer-based promotion, and group counseling. For supply of services, the lack of or inaccurate knowledge about vasectomy was also prevalent among providers, particularly among community-based health workers. Programmatic activities to improve service delivery included the use of evidence-based vasectomy techniques such as no-scalpel vasectomy, whole-site trainings, task shifting, cascade training, and mobile outreach. Finally, programmatic approaches to building a more enabling environment included engagement of governments and other community and religious leaders as well as campaigns with gender transformative messaging that countered common myths and encouraged men's positive engagement in family planning and reproductive health. In summary, a successful vasectomy program is comprised of the mutually reinforcing components of continual demand for services and access to and supply of well-trained providers. In addition, there is an underlying need for enabling policies within the cultural and gender environments that extend beyond vasectomy and include men not just as default partners of female family planning clients but as equal beneficiaries of family planning and reproductive health programs in their own right. Accelerating progress toward meaningful integration of vasectomy into a comprehensive contraceptive method mix is only possible when political and financial will are aligned and support the logistical and promotional activities of a male reproductive health agenda. PMID:28031302

Using EMBL-EBI services via Web interface and programmatically via Web Services

PubMed Central

Lopez, Rodrigo; Cowley, Andrew; Li, Weizhong; McWilliam, Hamish

2015-01-01

The European Bioinformatics Institute (EMBL-EBI) provides access to a wide range of databases and analysis tools that are of key importance in bioinformatics. As well as providing Web interfaces to these resources, Web Services are available using SOAP and REST protocols that enable programmatic access to our resources and allow their integration into other applications and analytical workflows. This unit describes the various options available to a typical researcher or bioinformatician who wishes to use our resources via Web interface or programmatically via a range of programming languages. PMID:25501941

Interpreting results of cluster surveys in emergency settings: is the LQAS test the best option?

PubMed

Bilukha, Oleg O; Blanton, Curtis

2008-12-09

Cluster surveys are commonly used in humanitarian emergencies to measure health and nutrition indicators. Deitchler et al. have proposed to use Lot Quality Assurance Sampling (LQAS) hypothesis testing in cluster surveys to classify the prevalence of global acute malnutrition as exceeding or not exceeding the pre-established thresholds. Field practitioners and decision-makers must clearly understand the meaning and implications of using this test in interpreting survey results to make programmatic decisions. We demonstrate that the LQAS test--as proposed by Deitchler et al.--is prone to producing false-positive results and thus is likely to suggest interventions in situations where interventions may not be needed. As an alternative, to provide more useful information for decision-making, we suggest reporting the probability of an indicator's exceeding the threshold as a direct measure of "risk". Such probability can be easily determined in field settings by using a simple spreadsheet calculator. The "risk" of exceeding the threshold can then be considered in the context of other aggravating and protective factors to make informed programmatic decisions.

Interpreting results of cluster surveys in emergency settings: is the LQAS test the best option?

PubMed Central

Bilukha, Oleg O; Blanton, Curtis

2008-01-01

Cluster surveys are commonly used in humanitarian emergencies to measure health and nutrition indicators. Deitchler et al. have proposed to use Lot Quality Assurance Sampling (LQAS) hypothesis testing in cluster surveys to classify the prevalence of global acute malnutrition as exceeding or not exceeding the pre-established thresholds. Field practitioners and decision-makers must clearly understand the meaning and implications of using this test in interpreting survey results to make programmatic decisions. We demonstrate that the LQAS test–as proposed by Deitchler et al. – is prone to producing false-positive results and thus is likely to suggest interventions in situations where interventions may not be needed. As an alternative, to provide more useful information for decision-making, we suggest reporting the probability of an indicator's exceeding the threshold as a direct measure of "risk". Such probability can be easily determined in field settings by using a simple spreadsheet calculator. The "risk" of exceeding the threshold can then be considered in the context of other aggravating and protective factors to make informed programmatic decisions. PMID:19068120

The impact of programmatic assessment on student learning: theory versus practice.

PubMed

Heeneman, Sylvia; Oudkerk Pool, Andrea; Schuwirth, Lambert W T; van der Vleuten, Cees P M; Driessen, Erik W

2015-05-01

It is widely acknowledged that assessment can affect student learning. In recent years, attention has been called to 'programmatic assessment', which is intended to optimise both learning functions and decision functions at the programme level of assessment, rather than according to individual methods of assessment. Although the concept is attractive, little research into its intended effects on students and their learning has been conducted. This study investigated the elements of programmatic assessment that students perceived as supporting or inhibiting learning, and the factors that influenced the active construction of their learning. The study was conducted in a graduate-entry medical school that implemented programmatic assessment. Thus, all assessment information, feedback and reflective activities were combined into a comprehensive, holistic programme of assessment. We used a qualitative approach and interviewed students (n = 17) in the pre-clinical phase of the programme about their perceptions of programmatic assessment and learning approaches. Data were scrutinised using theory-based thematic analysis. Elements from the comprehensive programme of assessment, such as feedback, portfolios, assessments and assignments, were found to have both supporting and inhibiting effects on learning. These supporting and inhibiting elements influenced students' construction of learning. Findings showed that: (i) students perceived formative assessment as summative; (ii) programmatic assessment was an important trigger for learning, and (iii) the portfolio's reflective activities were appreciated for their generation of knowledge, the lessons drawn from feedback, and the opportunities for follow-up. Some students, however, were less appreciative of reflective activities. For these students, the elements perceived as inhibiting seemed to dominate the learning response. The active participation of learners in their own learning is possible when learning is supported by programmatic assessment. Certain features of the comprehensive programme of assessment were found to influence student learning, and this influence can either support or inhibit students' learning responses. © 2015 John Wiley & Sons Ltd.

Food Safety When Preparing Holiday Meals

MedlinePlus

... disposable gloves, and changing them after handling raw foods is the safest way to prevent cross contamination. Don’t cook if you’re ill - Don’t prepare foods if you are experiencing symptoms of vomiting or ...

Pick Your Pick Me Up

Cancer.gov

Mood changes are common after you quit. You might be irritable, restless, or feel down or blue. If you’re experiencing these feelings after quitting smoking, there are many things you can do to help lift your mood.

Achieving human and machine accessibility of cited data in scholarly publications

PubMed Central

Starr, Joan; Castro, Eleni; Crosas, Mercè; Dumontier, Michel; Downs, Robert R.; Duerr, Ruth; Haak, Laurel L.; Haendel, Melissa; Herman, Ivan; Hodson, Simon; Hourclé, Joe; Kratz, John Ernest; Lin, Jennifer; Nielsen, Lars Holm; Nurnberger, Amy; Proell, Stefan; Rauber, Andreas; Sacchi, Simone; Smith, Arthur; Taylor, Mike; Clark, Tim

2015-01-01

Reproducibility and reusability of research results is an important concern in scientific communication and science policy. A foundational element of reproducibility and reusability is the open and persistently available presentation of research data. However, many common approaches for primary data publication in use today do not achieve sufficient long-term robustness, openness, accessibility or uniformity. Nor do they permit comprehensive exploitation by modern Web technologies. This has led to several authoritative studies recommending uniform direct citation of data archived in persistent repositories. Data are to be considered as first-class scholarly objects, and treated similarly in many ways to cited and archived scientific and scholarly literature. Here we briefly review the most current and widely agreed set of principle-based recommendations for scholarly data citation, the Joint Declaration of Data Citation Principles (JDDCP). We then present a framework for operationalizing the JDDCP; and a set of initial recommendations on identifier schemes, identifier resolution behavior, required metadata elements, and best practices for realizing programmatic machine actionability of cited data. The main target audience for the common implementation guidelines in this article consists of publishers, scholarly organizations, and persistent data repositories, including technical staff members in these organizations. But ordinary researchers can also benefit from these recommendations. The guidance provided here is intended to help achieve widespread, uniform human and machine accessibility of deposited data, in support of significantly improved verification, validation, reproducibility and re-use of scholarly/scientific data. PMID:26167542

Achieving human and machine accessibility of cited data in scholarly publications.

PubMed

Starr, Joan; Castro, Eleni; Crosas, Mercè; Dumontier, Michel; Downs, Robert R; Duerr, Ruth; Haak, Laurel L; Haendel, Melissa; Herman, Ivan; Hodson, Simon; Hourclé, Joe; Kratz, John Ernest; Lin, Jennifer; Nielsen, Lars Holm; Nurnberger, Amy; Proell, Stefan; Rauber, Andreas; Sacchi, Simone; Smith, Arthur; Taylor, Mike; Clark, Tim

Reproducibility and reusability of research results is an important concern in scientific communication and science policy. A foundational element of reproducibility and reusability is the open and persistently available presentation of research data. However, many common approaches for primary data publication in use today do not achieve sufficient long-term robustness, openness, accessibility or uniformity. Nor do they permit comprehensive exploitation by modern Web technologies. This has led to several authoritative studies recommending uniform direct citation of data archived in persistent repositories. Data are to be considered as first-class scholarly objects, and treated similarly in many ways to cited and archived scientific and scholarly literature. Here we briefly review the most current and widely agreed set of principle-based recommendations for scholarly data citation, the Joint Declaration of Data Citation Principles (JDDCP). We then present a framework for operationalizing the JDDCP; and a set of initial recommendations on identifier schemes, identifier resolution behavior, required metadata elements, and best practices for realizing programmatic machine actionability of cited data. The main target audience for the common implementation guidelines in this article consists of publishers, scholarly organizations, and persistent data repositories, including technical staff members in these organizations. But ordinary researchers can also benefit from these recommendations. The guidance provided here is intended to help achieve widespread, uniform human and machine accessibility of deposited data, in support of significantly improved verification, validation, reproducibility and re-use of scholarly/scientific data.

Prophylactic use of octreotide for asparaginase-induced acute pancreatitis.

PubMed

Sakaguchi, Sachi; Higa, Takeshi; Suzuki, Mitsuyoshi; Fujimura, Junya; Shimizu, Toshiaki

2017-08-01

In the present study, we sought to evaluate the prophylactic use of octreotide for asparaginase-induced acute pancreatitis. We reviewed the medical records of seven patients in two institutions who received prophylactic octreotide for re-administration of asparaginase after asparaginase-induced acute pancreatitis. Three patients completed asparaginase treatment without developing pancreatitis, and four experienced recurrence of pancreatitis. A literature search using PubMed identified four additional patients in whom asparaginase was successfully re-administered with octreotide. Prophylactic use of octreotide may, thus, be warranted for patients who would benefit from re-administration of asparaginase for cancer treatment; however, careful observation is needed to monitor for breakthrough recurrence of pancreatitis.

The X-20 space plane: Past innovation, future vision

NASA Astrophysics Data System (ADS)

Sunday, Terry L.; London, John R.

In November 1957, the U.S. Air Force initiated an aerospace project that was one of the most innovative concepts of its day, and also provided an accurate glimpse into the future. The X-20 space plane, known as Dyna-Soar, never reached operational status—it was cancelled in December 1963, before the first prototype was built. But even though the diminutive vehicle never flew, technological advances made during its development laid the foundation for many later manned space systems, including some as new as tomorrow's headlines. The paper examines both the history and the technology of Dyna-Soar. The space plane's unique design and its proposed missions are examined, along with the ever-changing political, economic and programmatic environments that led to its conception, its long, painful gestation period, and its demise. The X-20 premiered many innovations to solve the challenges of launch, manned orbital operations and re-entry for a re-usable spacecraft. Many of these technologies did not reach fruition until decades later. Based largely on recently declassified material, this paper places Dyna-Soar into a broad historical context as an interesting research vehicle concept from three decades past, and as the purveyor of a technological legacy whose impacts are still being felt today.

77 FR 38796 - Alabama Power Company; Holt Hydroelectric Project; Notice of Revised Restricted Service List for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... Power Company; Holt Hydroelectric Project; Notice of Revised Restricted Service List for a Programmatic... Hydroelectric Project No. 2203. The programmatic agreement, when executed by the Commission, the Alabama SHPO...

"They Think That if You're a Teacher Here?…?You're Not Clever Enough to Be a Proper Teacher": The Courtesy Stigma Experienced by Teachers Employed at Schools for Pupils with Behavioural, Emotional and Social Difficulties (BESD)

ERIC Educational Resources Information Center

Broomhead, Karen E.

2016-01-01

A wealth of literature has identified that children with behavioural, emotional and social difficulties (BESD) and their families are frequently stigmatised due to the perceived controllable and "invisible" nature of this special educational need (SEN). Yet little research has considered the impact of this stigma on another group of…

A Framework for Daylighting Optimization in Whole Buildings with OpenStudio

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2016-08-12

We present a toolkit and workflow for leveraging the OpenStudio (Guglielmetti et al. 2010) platform to perform daylighting analysis and optimization in a whole building energy modeling (BEM) context. We have re-implemented OpenStudio's integrated Radiance and EnergyPlus functionality as an OpenStudio Measure. The OpenStudio Radiance Measure works within the OpenStudio Application and Parametric Analysis Tool, as well as the OpenStudio Server large scale analysis framework, allowing a rigorous daylighting simulation to be performed on a single building model or potentially an entire population of programmatically generated models. The Radiance simulation results can automatically inform the broader building energy model, andmore » provide dynamic daylight metrics as a basis for decision. Through introduction and example, this paper illustrates the utility of the OpenStudio building energy modeling platform to leverage existing simulation tools for integrated building energy performance simulation, daylighting analysis, and reportage.« less

NASA's Morphing Project Research Summaries in Fiscal Year 2002

NASA Technical Reports Server (NTRS)

McGowan, Anna-Maria R.; Waszak, Martin R.

2005-01-01

The Morphing Project at the National Aeronautics and Space Agency s (NASA) Langley Research Center (LaRC) is part of the Breakthrough Vehicle Technologies Project, Vehicle Systems Program that conducts fundamental research on advanced technologies for future flight vehicles. The objectives of the Morphing Project are to develop and assess the advanced technologies and integrated component concepts to enable efficient, multi-point adaptability of flight vehicles; primarily through the application of adaptive structures and adaptive flow control to substantially alter vehicle performance characteristics. This document is a compilation of research summaries and other information on the project for fiscal year 2002. The focus is to provide a brief overview of the project content, technical results and lessons learned. At the time of publication, the Vehicle Systems Program (which includes the Morphing Project) is undergoing a program re-planning and reorganization. Accordingly, the programmatic descriptions of this document pertain only to the program as of fiscal year 2002.

Orion Heat Shield Manufacturing Producibility Improvements for the EM-1 Flight Test Program

NASA Technical Reports Server (NTRS)

Koenig, William J.; Stewart, Michael; Harris, Richard F.

2018-01-01

This paper describes how the ORION program is incorporating improvements in the heat shield design and manufacturing processes reducing programmatic risk and ensuring crew safety in support of NASA's Exploration missions. The approach for the EFT-1 heat shield utilized a low risk Apollo heritage design and manufacturing process using an Avcoat TPS ablator with a honeycomb substrate to provide a one piece heat shield to meet the mission re-entry heating environments. The EM-1 mission will have additional flight systems installed to fly to the moon and return to Earth. Heat shield design and producibility improvements have been incorporated in the EM-1 vehicle to meet deep space mission requirements. The design continues to use the Avcoat material, but in a block configuration to enable improvements in consistant and repeatable application processes using tile bonding experience developed on the Space Shuttle Transportation System Program.

Safety of {sup 90}Y Radioembolization in Patients Who Have Undergone Previous External Beam Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lam, Marnix G.E.H.; Department of Radiology and Nuclear Medicine, University Medical Center Utrecht; Abdelmaksoud, Mohamed H.K.

2013-10-01

Purpose: Previous external beam radiation therapy (EBRT) is theoretically contraindicated for yttrium-90 ({sup 90}Y) radioembolization (RE) because the liver has a lifetime tolerance to radiation before becoming vulnerable to radiation-induced liver disease. We analyzed the safety of RE as salvage treatment in patients who had previously undergone EBRT. Methods and Materials: Between June 2004 and December 2010, a total of 31 patients who had previously undergone EBRT were treated with RE. Three-dimensional treatment planning with dose–volume histogram (DVH) analysis of the liver was used to calculate the EBRT liver dose. Liver-related toxicities including RE-induced liver disease (REILD) were reviewed andmore » classified according to Common Terminology Criteria for Adverse Events version 4.02. Results: The mean EBRT and RE liver doses were 4.40 Gy (range, 0-23.13 Gy) and 57.9 Gy (range, 27.0-125.9 Gy), respectively. Patients who experienced hepatotoxicity (≥grade2; n=12) had higher EBRT mean liver doses (7.96 ± 8.55 Gy vs 1.62 ± 3.39 Gy; P=.037), the only independent predictor in multivariate analysis. DVH analysis showed that the fraction of liver exposed to ≥30 Gy (V30) was the strongest predictor of hepatotoxicity (10.14% ± 12.75% vs 0.84% ± 3.24%; P=.006). All patients with V30 >13% experienced hepatotoxicity. Fatal REILD (n=2) occurred at the 2 highest EBRT mean liver doses (20.9 Gy and 23.1 Gy) but also at the highest cumulative liver doses (91.8 Gy and 149 Gy). Conclusions: Prior exposure of the liver to EBRT may lead to increased liver toxicity after RE treatment, depending on fractional liver exposure and dose level. The V30 was the strongest predictor of toxicity. RE appears to be safe for the treatment of hepatic malignancies only in patients who have had limited hepatic exposure to prior EBRT.« less

Psychological intimate partner violence and sexual risk behavior: examining the role of distinct posttraumatic stress disorder symptoms in the partner violence-sexual risk link.

PubMed

Overstreet, Nicole M; Willie, Tiara C; Hellmuth, Julianne C; Sullivan, Tami P

2015-01-01

Research has examined how physical and sexual intimate partner violence (IPV) victimization increases sexual risk behavior, yet research is lacking on 1) the effect of psychological IPV on sexual risk behavior and 2) factors through which psychological IPV may be linked to sexual risk behavior. The current study examined the relationship between psychological IPV and sexual risk behavior controlling for other forms of IPV (i.e., physical and sexual) in a sample of 186 human immunodeficiency virus (HIV)-negative community women currently experiencing IPV. Further, this study examined the potential mediating effects of four posttraumatic stress disorder (PTSD) symptom severity clusters (i.e., re-experiencing, avoidance, numbing, and hyperarousal) on this relationship. Results revealed that greater severity of psychological IPV was uniquely and directly related to greater sexual risk behavior. Additionally, of the four PTSD symptom severity clusters, only avoidance symptom severity mediated the relationship between psychological IPV and sexual risk behavior. Implications for addressing psychological IPV and PTSD to improve women's sexual health outcomes are discussed. Copyright © 2015 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

Urban transportation : challenges to widespread deployment of intelligent transportation systems : report to Congressional committees

DOT National Transportation Integrated Search

The federal government can take programmatic and financial actions to : promote the deployment of intelligent transportation systems. The : programmatic actions include providing technical assistance and training : to state and local officials, disse...

75 FR 56092 - Notice Modifying Restricted Service List for a Programmatic Agreement for Managing Properties...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

... Inclusion in the National Register of Historic Places; Marseilles Land and Water Company September 3, 2010... Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the National Register...

FY 2014 LDRD Annual Report Project Summaries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tomchak, Dena

The FY 2014 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support future DOE missions and national research priorities. LDRD is essential to INL - it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enahnces technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

Accommodating complexity and human behaviors in decision analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Backus, George A.; Siirola, John Daniel; Schoenwald, David Alan

2007-11-01

This is the final report for a LDRD effort to address human behavior in decision support systems. One sister LDRD effort reports the extension of this work to include actual human choices and additional simulation analyses. Another provides the background for this effort and the programmatic directions for future work. This specific effort considered the feasibility of five aspects of model development required for analysis viability. To avoid the use of classified information, healthcare decisions and the system embedding them became the illustrative example for assessment.

Commentary on Community Mental Health and the Common Good.

PubMed

Arrigo, Bruce; Davidson, Larry

2017-07-01

This article comments on the core question addressed by this Special Issue: "What's good about public sector mental health?" Theoretical, empirical, and programmatic insights derived from the Issue's six article contributions guide the overall commentary. Several points of thematic overlap are featured in these preliminary observations, and these themes are suggestive for directing future research (e.g., citizenship studies) in the field of community mental health. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

Final Programmatic Environmental Impact Statement for Defense Threat Reduction Agency (DTRA) Activities on White Sands Missile Range, New Mexico

DTIC Science & Technology

2007-05-01

taggants south of Mockingbird Gap and the limited number of simulants met the Agency requirements. It was recognized at that time if either situation...from attack. * A new test bed for HTD testing is proposed at Mockingbird South. Alternative one, the preferred alternative, would allow DTRA to expand...HTD tests, and explosive tests have the potential to directly injure or kill native fauna from flying debris and blast overpressure. Craters

When do gamblers help themselves? Self-discontinuity increases self-directed change over time.

PubMed

Kim, Hyoun S; Wohl, Michael J A; Salmon, Melissa; Santesso, Diane

2017-01-01

Most disordered gamblers fail to take the necessary action to change their behavior. When action is taken, it is typically done under self-direction. Yet, little is known about what motivates gamblers to engage in self-directed change as researchers have focused almost exclusively on barriers to treatment seeking. Herein, we tested whether self-discontinuity (i.e., the notion that the self has undergone fundamental changes as a result of one's gambling) predicts self-directed change among gamblers experiencing sub-clinical levels of disordered gambling. Further, we tested whether this relationship would hold when controlling for feelings of shame and guilt about one's gambling as well as self-stigma as a disordered gambler (i.e., known barriers to change). To this end, 195 gamblers from the community completed a questionnaire battery that contained the variables of interest. Six months later, participants were re-contacted to assess whether they engaged in self-directed change. As hypothesized, the likelihood that self-directed change was attempted increased to the extent participants reported feeling self-discontinuous - an effect that remained significant when controlling for shame, guilt, and self-stigma. Results suggest that heightening the awareness that the gambling has fundamentally changed the self increases the likelihood of gamblers taking action to change their disordered gambling behaviors. Copyright © 2016. Published by Elsevier Ltd.

Gender as a moderator in predicting re-arrest among treated drug-involved offenders.

PubMed

Yang, Yang; Knight, Kevin; Joe, George W; Rowan, Grace A; Lehman, Wayne E K; Flynn, Patrick M

2015-02-01

The primary aim of the current study is to explore gender differences on the relationships of pre-treatment risk factors and psychosocial functioning with time to re-arrest following termination from prison. The sample consisted of 384 males and 313 females who were admitted to four prison-based substance abuse treatment programs. Results showed that female inmates experienced a longer time to re-arrest than male inmates. Higher self-reported ratings of decision making confidence and peer support were associated with a lower likelihood of re-arrest for males. Males with higher self-esteem ratings were more likely to be re-arrested than males who reported lower self-esteem. Females with more self-reported criminal involvement had a higher rate of re-arrest than did those with less criminal involvement. In contrast to males, females with relatively high self-reported self-esteem had a lower rate of re-arrest than their counterparts who reported low self-esteem. Clinical implications include the importance of enhancing decision-making confidence and peer support for males and self-esteem for females. Copyright © 2015 Elsevier Inc. All rights reserved.

36 CFR 800.14 - Federal agency program alternatives.

Code of Federal Regulations, 2010 CFR

2010-07-01

... program or the resolution of adverse effects from certain complex project situations or multiple... by the agreement. (3) Developing programmatic agreements for complex or multiple undertakings. Consultation to develop a programmatic agreement for dealing with the potential adverse effects of complex...

78 FR 71561 - Notice of Intent To Prepare a Supplemental Programmatic Environmental Impact Statement for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-29

... of documents #0;appearing in this section. #0; #0; #0; #0;#0;Federal Register / Vol. 78, No. 230... contracts. The 2008 CRP Programmatic EA (PEA) and FONSI, which evaluated mandatory changes to CRP...

33 CFR 385.1 - Purpose of the programmatic regulations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... regulations. 385.1 Section 385.1 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General... of Project Implementation Reports, Project Cooperation Agreements, plans and specifications, Pilot...

33 CFR 385.1 - Purpose of the programmatic regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... regulations. 385.1 Section 385.1 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General... of Project Implementation Reports, Project Cooperation Agreements, plans and specifications, Pilot...

33 CFR 385.1 - Purpose of the programmatic regulations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... regulations. 385.1 Section 385.1 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General... of Project Implementation Reports, Project Cooperation Agreements, plans and specifications, Pilot...

33 CFR 385.1 - Purpose of the programmatic regulations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... regulations. 385.1 Section 385.1 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General... of Project Implementation Reports, Project Cooperation Agreements, plans and specifications, Pilot...

33 CFR 385.1 - Purpose of the programmatic regulations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... regulations. 385.1 Section 385.1 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General... of Project Implementation Reports, Project Cooperation Agreements, plans and specifications, Pilot...

Using EMBL-EBI Services via Web Interface and Programmatically via Web Services.

PubMed

Lopez, Rodrigo; Cowley, Andrew; Li, Weizhong; McWilliam, Hamish

2014-12-12

The European Bioinformatics Institute (EMBL-EBI) provides access to a wide range of databases and analysis tools that are of key importance in bioinformatics. As well as providing Web interfaces to these resources, Web Services are available using SOAP and REST protocols that enable programmatic access to our resources and allow their integration into other applications and analytical workflows. This unit describes the various options available to a typical researcher or bioinformatician who wishes to use our resources via Web interface or programmatically via a range of programming languages. Copyright © 2014 John Wiley & Sons, Inc.

Space station accommodations for life sciences research facilities. Phase 1: Conceptual design and programmatics studies for Missions SAAX0307, SAAX0302 and the transition from SAAX0307 to SAAX0302. Volume 2: Study results

NASA Technical Reports Server (NTRS)

1986-01-01

Lockheed Missiles and Space Company's conceptual designs and programmatics for a Space Station Nonhuman Life Sciences Research Facility (LSRF) are presented. Conceptual designs and programmatics encompass an Initial Orbital Capability (IOC) LSRF, a growth or follow-on Orbital Capability (FOC), and the transitional process required to modify the IOC LSFR to the FOC LSFR. The IOC and FOC LSFRs correspond to missions SAAX0307 and SAAX0302 of the Space Station Mission Requirements Database, respectively.

Resource utilization and charges of patients with and without diagnosed venous thromboembolism during primary hospitalization and after elective inpatient surgery: a retrospective study.

PubMed

Sepassi, Aryana; Chingcuanco, Francine; Gordon, Ronald; Meier, Angela; Divino, Victoria; DeKoven, Mitch; Ben-Joseph, Rami

2018-06-01

To assess incremental charges of patients experiencing venous thromboembolisms (VTE) across various types of elective inpatient surgical procedures with administration of general anesthesia in the US. The authors performed a retrospective study utilizing data from a nationwide hospital operational records database from July 2014 through June 2015 to compare a group of inpatients experiencing a VTE event post-operatively to a propensity score matched group of inpatients who did not experience a VTE. Patients included in the analysis had a hospital admission for an elective inpatient surgical procedure with the use of general anesthesia. Procedures of the heart, brain, lungs, and obstetrical procedures were excluded, as these procedures often require a scheduled ICU stay post-operatively. Outcomes examined included VTE events during hospitalization, length of stay, unscheduled ICU transfers, number of days spent in the ICU if transferred, 3- and 30-day re-admissions, and total hospital charges incurred. The study included 17,727 patients undergoing elective inpatient surgical procedures. Of these, 36 patients who experienced a VTE event were matched to 108 patients who did not. VTE events occurred in 0.2% of the study population, with most events occurring for patients undergoing total knee replacement. VTE patients had a mean total hospital charge of $60,814 vs $48,325 for non-VTE patients, resulting in a mean incremental charge of $11,979 (p < .05). Compared to non-VTE patients, VTE patients had longer length of stay (5.9 days vs 3.7 days, p < .001), experienced a higher rate of 3-day re-admissions (3 vs 0 patients) and 30-day re-admissions (7 vs 2 patients). Patients undergoing elective inpatient surgical procedures with general anesthesia who had a VTE event during their primary hospitalization had a significantly longer length of stay and significantly higher total hospital charges than comparable patients without a VTE event.

Neurobiological correlates of distinct post-traumatic stress disorder symptom profiles during threat anticipation in combat veterans.

PubMed

Grupe, D W; Wielgosz, J; Davidson, R J; Nitschke, J B

2016-07-01

Previous research in post-traumatic stress disorder (PTSD) has identified disrupted ventromedial prefrontal cortex (vmPFC) function in those with v. without PTSD. It is unclear whether this brain region is uniformly affected in all individuals with PTSD, or whether vmPFC dysfunction is related to individual differences in discrete features of this heterogeneous disorder. In a sample of 51 male veterans of Operation Enduring Freedom/Operation Iraqi Freedom, we collected functional magnetic resonance imaging data during a novel threat anticipation task with crossed factors of threat condition and temporal unpredictability. Voxelwise regression analyses related anticipatory brain activation to individual differences in overall PTSD symptom severity, as well as individual differences in discrete symptom subscales (re-experiencing, emotional numbing/avoidance, and hyperarousal). The vmPFC showed greater anticipatory responses for safety relative to threat, driven primarily by deactivation during threat anticipation. During unpredictable threat anticipation, increased PTSD symptoms were associated with relatively greater activation for threat v. However, simultaneous regression on individual symptom subscales demonstrated that this effect was driven specifically by individual differences in hyperarousal symptoms. Furthermore, this analysis revealed an additional, anatomically distinct region of the vmPFC in which re-experiencing symptoms were associated with greater activation during threat anticipation. Increased anticipatory responses to unpredictable threat in distinct vmPFC subregions were uniquely associated with elevated hyperarousal and re-experiencing symptoms in combat veterans. These results underscore the disruptive impact of uncertainty for veterans, and suggest that investigating individual differences in discrete aspects of PTSD may advance our understanding of underlying neurobiological mechanisms.

Delayed Single Stage Perineal Posterior Urethroplasty.

PubMed

Ali, Shahzad; Shahnawaz; Shahzad, Iqbal; Baloch, Muhammad Umar

2015-06-01

To determine the delayed single stage perineal posterior urethroplasty for treatment of posterior urethral stricture/distraction defect. Descriptive case series. Department of Urology, Jinnah Postgraduate Medical Centre, Karachi, from January 2009 to December 2011. Patients were selected for delayed single stage perineal posterior urethroplasty for treatment of posterior urethral stricture / distraction defect. All were initially suprapubically catheterized followed by definitive surgery after at least 3 months. Thirty male patients were analyzed with a mean follow-up of 10 months, 2 patients were excluded as they developed failure in first 3 months postoperatively. Mean patient's age was 26.25 ± 7.9 years. On follow-up, 7 patients (23.3%) experienced recurrent stricture during first 10 months. Five (16.6%) patients were treated successfully with single direct visual internal urethrotomy. Two patients (6.6%) had more than one direct visual internal urethrotomy and considered failed. Re-do perineal urethroplasty was eventually performed. The overall success rate was 93.3% with permissive criteria allowing single direct visual internal urethrotomy and 76.6% with strict criteria allowing no more procedures postoperatively. Posterior anastomotic urethroplasty offers excellent long-term results to patients with posterior urethral trauma and distraction defect even after multiple prior procedures.

7 CFR 3015.113 - Programmatic changes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER... project than was anticipated when the award was made. (d) Transferring work and providing financial... performance of the substantive programmatic work, and for providing any form of financial assistance to...

78 FR 56869 - Nuclear Infrastructure Programmatic Environmental Impact Statement Supplement Analysis...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-16

... DEPARTMENT OF ENERGY Nuclear Infrastructure Programmatic Environmental Impact Statement Supplement... Statement for Accomplishing Expanded Civilian Nuclear Energy Research and Development and Isotope Production...), Office of Nuclear Energy, U.S. Department of Energy, 1000 Independence Ave. SW., Washington, DC 20585...

33 CFR 385.20 - Restoration Coordination and Verification (RECOVER).

Code of Federal Regulations, 2013 CFR

2013-07-01

... Verification (RECOVER). 385.20 Section 385.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION... technical team described in the “Final Integrated Feasibility Report and Programmatic Environmental Impact...

33 CFR 385.20 - Restoration Coordination and Verification (RECOVER).

Code of Federal Regulations, 2014 CFR

2014-07-01

... Verification (RECOVER). 385.20 Section 385.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION... technical team described in the “Final Integrated Feasibility Report and Programmatic Environmental Impact...

33 CFR 385.20 - Restoration Coordination and Verification (RECOVER).

Code of Federal Regulations, 2012 CFR

2012-07-01

... Verification (RECOVER). 385.20 Section 385.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION... technical team described in the “Final Integrated Feasibility Report and Programmatic Environmental Impact...

33 CFR 385.20 - Restoration Coordination and Verification (RECOVER).

Code of Federal Regulations, 2011 CFR

2011-07-01

... Verification (RECOVER). 385.20 Section 385.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION... technical team described in the “Final Integrated Feasibility Report and Programmatic Environmental Impact...

NASA Post-Columbia Safety & Mission Assurance, Review and Assessment Initiatives

NASA Astrophysics Data System (ADS)

Newman, J. Steven; Wander, Stephen M.; Vecellio, Don; Miller, Andrew J.

2005-12-01

On February 1, 2003, NASA again experienced a tragic accident as the Space Shuttle Columbia broke apart upon reentry, resulting in the loss of seven astronauts. Several of the findings and observations of the Columbia Accident Investigation Board addressed the need to strengthen the safety and mission assurance function at NASA. This paper highlights key steps undertaken by the NASA Office of Safety and Mission Assurance (OSMA) to establish a stronger and more- robust safety and mission assurance function for NASA programs, projects, facilities and operations. This paper provides an overview of the interlocking OSMA Review and Assessment Division (RAD) institutional and programmatic processes designed to 1) educate, inform, and prepare for audits, 2) verify requirements flow-down, 3) verify process capability, 4) verify compliance with requirements, 5) support risk management decision making, 6) facilitate secure web- based collaboration, and 7) foster continual improvement and the use of lessons learned.

Using multilevel, multisource needs assessment data for planning community interventions.

PubMed

Levy, Susan R; Anderson, Emily E; Issel, L Michele; Willis, Marilyn A; Dancy, Barbara L; Jacobson, Kristin M; Fleming, Shirley G; Copper, Elizabeth S; Berrios, Nerida M; Sciammarella, Esther; Ochoa, Mónica; Hebert-Beirne, Jennifer

2004-01-01

African Americans and Latinos share higher rates of cardiovascular disease (CVD) and diabetes compared with Whites. These diseases have common risk factors that are amenable to primary and secondary prevention. The goal of the Chicago REACH 2010-Lawndale Health Promotion Project is to eliminate disparities related to CVD and diabetes experienced by African Americans and Latinos in two contiguous Chicago neighborhoods using a community-based prevention approach. This article shares findings from the Phase 1 participatory planning process and discusses the implications these findings and lessons learned may have for programs aiming to reduce health disparities in multiethnic communities. The triangulation of data sources from the planning phase enriched interpretation and led to more creative and feasible suggestions for programmatic interventions across the four levels of the ecological framework. Multisource data yielded useful information for program planning and a better understanding of the cultural differences and similarities between African Americans and Latinos.

Celebrating 40 Years of the Midwest Nursing Research Society.

PubMed

Hershberger, Patricia E; Wynd, Christine A; Glass, Laurie K; O'Connell, Karen M; Fitzpatrick, Joyce J; Bergstrom, Nancy; Lusk, Sally Lechlitner

2017-05-01

The Midwest Nursing Research Society (MNRS) recently held its 40th annual conference and celebrated four decades of nursing research in the Midwest. MNRS continues to be one of the largest nursing research societies in the United States. Over the years, a vast majority of programmatic initiatives included education and tangible support for novice and experienced nurse researchers. In this article, the background for development of MNRS is reviewed with examination of driving forces that led to its creation. Three past presidents, Dr. Joyce Fitzpatrick, the first President of MNRS (1980-1981); Dr. Nancy Bergstrom, the eighth President (1993-1995); and Dr. Sally Lusk, the 14th President (2005-2007), discuss challenges, opportunities, and the exceptional progress made toward fostering excellence in nursing research for the Midwest and contributing to nursing science on a national and global scale. Lessons from the past as well as opportunities for the future are addressed.

Financial dimensions of veterinary medical education: an economist's perspective.

PubMed

Lloyd, James W

2013-01-01

Much discussion has transpired in recent years related to the rising cost of veterinary medical education and the increasing debt loads of graduating veterinarians. Underlying these trends are fundamental changes in the funding structure of higher education in general and of academic veterinary medicine specifically. As a result of the ongoing disinvestment by state governments in higher education, both tuition rates and academic programs have experienced a substantial impact across US colleges and schools of veterinary medicine. Programmatically, the effects have spanned the entire range of teaching, research, and service activities. For graduates, both across higher education and in veterinary medicine specifically, the impact has been steadily increasing levels of student debt. Although the situation is clearly worrisome, viable repayment options exist for these escalating debt loads. In combination with recent income and employment trends for veterinarians, these options provide a basis for cautious optimism for the future.

The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations.

PubMed

Huang, Linda; Fernandes, Helen; Zia, Hamid; Tavassoli, Peyman; Rennert, Hanna; Pisapia, David; Imielinski, Marcin; Sboner, Andrea; Rubin, Mark A; Kluk, Michael; Elemento, Olivier

2017-05-01

This paper describes the Precision Medicine Knowledge Base (PMKB; https://pmkb.weill.cornell.edu ), an interactive online application for collaborative editing, maintenance, and sharing of structured clinical-grade cancer mutation interpretations. PMKB was built using the Ruby on Rails Web application framework. Leveraging existing standards such as the Human Genome Variation Society variant description format, we implemented a data model that links variants to tumor-specific and tissue-specific interpretations. Key features of PMKB include support for all major variant types, standardized authentication, distinct user roles including high-level approvers, and detailed activity history. A REpresentational State Transfer (REST) application-programming interface (API) was implemented to query the PMKB programmatically. At the time of writing, PMKB contains 457 variant descriptions with 281 clinical-grade interpretations. The EGFR, BRAF, KRAS, and KIT genes are associated with the largest numbers of interpretable variants. PMKB's interpretations have been used in over 1500 AmpliSeq tests and 750 whole-exome sequencing tests. The interpretations are accessed either directly via the Web interface or programmatically via the existing API. An accurate and up-to-date knowledge base of genomic alterations of clinical significance is critical to the success of precision medicine programs. The open-access, programmatically accessible PMKB represents an important attempt at creating such a resource in the field of oncology. The PMKB was designed to help collect and maintain clinical-grade mutation interpretations and facilitate reporting for clinical cancer genomic testing. The PMKB was also designed to enable the creation of clinical cancer genomics automated reporting pipelines via an API. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association.

The cancer precision medicine knowledge base for structured clinical-grade mutations and interpretations

PubMed Central

Huang, Linda; Fernandes, Helen; Zia, Hamid; Tavassoli, Peyman; Rennert, Hanna; Pisapia, David; Imielinski, Marcin; Sboner, Andrea; Rubin, Mark A; Kluk, Michael

2017-01-01

Objective: This paper describes the Precision Medicine Knowledge Base (PMKB; https://pmkb.weill.cornell.edu), an interactive online application for collaborative editing, maintenance, and sharing of structured clinical-grade cancer mutation interpretations. Materials and Methods: PMKB was built using the Ruby on Rails Web application framework. Leveraging existing standards such as the Human Genome Variation Society variant description format, we implemented a data model that links variants to tumor-specific and tissue-specific interpretations. Key features of PMKB include support for all major variant types, standardized authentication, distinct user roles including high-level approvers, and detailed activity history. A REpresentational State Transfer (REST) application-programming interface (API) was implemented to query the PMKB programmatically. Results: At the time of writing, PMKB contains 457 variant descriptions with 281 clinical-grade interpretations. The EGFR, BRAF, KRAS, and KIT genes are associated with the largest numbers of interpretable variants. PMKB’s interpretations have been used in over 1500 AmpliSeq tests and 750 whole-exome sequencing tests. The interpretations are accessed either directly via the Web interface or programmatically via the existing API. Discussion: An accurate and up-to-date knowledge base of genomic alterations of clinical significance is critical to the success of precision medicine programs. The open-access, programmatically accessible PMKB represents an important attempt at creating such a resource in the field of oncology. Conclusion: The PMKB was designed to help collect and maintain clinical-grade mutation interpretations and facilitate reporting for clinical cancer genomic testing. The PMKB was also designed to enable the creation of clinical cancer genomics automated reporting pipelines via an API. PMID:27789569

Hybrid Pluggable Processing Pipeline (HyP3): Programmatic Access to Cloud-Based Processing of SAR Data

NASA Astrophysics Data System (ADS)

Weeden, R.; Horn, W. B.; Dimarchi, H.; Arko, S. A.; Hogenson, K.

2017-12-01

A problem often faced by Earth science researchers is the question of how to scale algorithms that were developed against few datasets and take them to regional or global scales. This problem only gets worse as we look to a future with larger and larger datasets becoming available. One significant hurdle can be having the processing and storage resources available for such a task, not to mention the administration of those resources. As a processing environment, the cloud offers nearly unlimited potential for compute and storage, with limited administration required. The goal of the Hybrid Pluggable Processing Pipeline (HyP3) project was to demonstrate the utility of the Amazon cloud to process large amounts of data quickly and cost effectively. Principally built by three undergraduate students at the ASF DAAC, the HyP3 system relies on core Amazon cloud services such as Lambda, Relational Database Service (RDS), Elastic Compute Cloud (EC2), Simple Storage Service (S3), and Elastic Beanstalk. HyP3 provides an Application Programming Interface (API) through which users can programmatically interface with the HyP3 system; allowing them to monitor and control processing jobs running in HyP3, and retrieve the generated HyP3 products when completed. This presentation will focus on the development techniques and enabling technologies that were used in developing the HyP3 system. Data and process flow, from new subscription through to order completion will be shown, highlighting the benefits of the cloud for each step. Because the HyP3 system can be accessed directly from a user's Python scripts, powerful applications leveraging SAR products can be put together fairly easily. This is the true power of HyP3; allowing people to programmatically leverage the power of the cloud.

Stroboscopic Goggles as a Countermeasure for Dynamic Visual Acuity and Landing Sickness in Crewmembers Returning from Long-Duration Spaceflight

NASA Technical Reports Server (NTRS)

Rosenberg, M. J. F.; Kreutzberg, G. A.; Peters, B. T.; Reschke, M. F.

2017-01-01

Long-term exposure to microgravity causes sensorimotor adaptations that result in functional deficits upon returning to a gravitational environment. At landing, the vestibular system and the central nervous system, responsible for coordinating head and eye movements via the vestibulo-occular reflex (VOR), are adapted to microgravity and must re-adapt to the Earth's gravitational environment. This re-adaptation causes decrements in gaze control and dynamic visual acuity, with astronauts reporting oscillopsia and blurred vision. These effects are caused by retinal slip, or the inability to keep an image focused on their retina, which is thought to drive motion sickness symptoms experienced upon landing. Retinal slip can be estimated by dynamic visual acuity (DVA); visual acuity while in motion. Peters et al. (2011) find that DVA is worsened in astronauts by an average of 0.75 eye-chart lines one day after landing. Previously, the use of stroboscopic goggles has shown to be effective in minimizing motion sickness symptoms due to retinal slip (Reschke et al. 2007). In this study, we simulated the decrement in DVA caused by sensorimotor re-adaptation by using minifying lenses and then testing the efficacy of stroboscopic goggles in preventing retinal slip and improving DVA. Dynamic visual acuity is assessed using an oscillating chair developed in the Neuroscience Laboratory at JSC. This chair is motor-driven and oscillates vertically at 2 Hz with a vertical displacement of +/- 2 cm to simulate the vertical translations that occur while walking. As the subject is being oscillated, they are asked to discern the direction of Landolt-C optotypes of varying sizes and record their direction using a gamepad. The visual acuity thresholds are determined using an algorithm that alters the size of the optotype based on the previous responses of the subject using a forced-choice best parameter estimation that is able to rapidly converge on the threshold value. Visual acuity thresholds were determined both for static (seated) and dynamic (oscillating) conditions. Dynamic visual acuity is defined as the difference between the dynamic and static conditions. We found that healthy subjects (n=20) have a significantly impaired DVA while wearing the minifying lenses, demonstrating that the VOR is in an adaptive state and retinal slip is occurring. When subjects' acuity was tested wearing the stroboscopic goggles with the minifying lenses, there was no significant difference in their DVA compared to their baseline DVA. This suggests that stroboscopic goggles are preventing retinal slip and would function as an efficient countermeasure for VOR adaptations and thus help mitigate landing sickness symptoms experienced by long-duration crewmembers. These goggles might also be used to counter blurred vision (caused by retinal slip) experienced by crewmembers during launch where the vehicle vibrations are greatest. The stroboscopic effect could be built into a section of their head mounted displays on the visor of their helmets to be used in these high vibration situation if a mission critical task is necessary.

A Systematic Approach to Programmatic Assessment

ERIC Educational Resources Information Center

Moffit, Dani M.; Mansell, Jamie L.; Russ, Anne C.

2016-01-01

Context: Accrediting bodies and universities increasingly require evidence of student learning within courses and programs. Within athletic training, programmatic assessment has been a source of angst for program directors. While there are many ways to assess educational programs, this article introduces 1 systematic approach. Objective: This…

Programmatic Agreements for Project-Level Air Quality Analyses : NCHRP 25-25 Task 78

DOT National Transportation Integrated Search

2015-09-01

The research performed under Task 78 was divided into two phases. The first phase involved development of a draft Programmatic Agreement (PA) template and a draft Technical Support Document (TSD) template for project-level carbon monoxide (CO) hot-sp...

10 CFR 603.895 - Protection of information in programmatic reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Section 603.895 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Related to Other Administrative Matters Financial and Programmatic Reporting § 603.895... transaction that would be trade secret, or commercial or financial information that is privileged or...

75 FR 69475 - Notice Regarding Changed Venue for Public Hearing On a Draft Programmatic Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... NATIONAL SCIENCE FOUNDATION Notice Regarding Changed Venue for Public Hearing On a Draft Programmatic Environmental Impact Statement/Overseas Environmental Impact Statement (PEIS) AGENCY: National Science Foundation. ACTION: Notice regarding changed venue for public hearing. SUMMARY: The National...

Modular programming for tuberculosis control, the "AuTuMN" platform.

PubMed

Trauer, James McCracken; Ragonnet, Romain; Doan, Tan Nhut; McBryde, Emma Sue

2017-08-07

Tuberculosis (TB) is now the world's leading infectious killer and major programmatic advances will be needed if we are to meet the ambitious new End TB Targets. Although mathematical models are powerful tools for TB control, such models must be flexible enough to capture the complexity and heterogeneity of the global TB epidemic. This includes simulating a disease that affects age groups and other risk groups differently, has varying levels of infectiousness depending upon the organ involved and varying outcomes from treatment depending on the drug resistance pattern of the infecting strain. We adopted sound basic principles of software engineering to develop a modular software platform for simulation of TB control interventions ("AuTuMN"). These included object-oriented programming, logical linkage between modules and consistency of code syntax and variable naming. The underlying transmission dynamic model incorporates optional stratification by age, risk group, strain and organ involvement, while our approach to simulating time-variant programmatic parameters better captures the historical progression of the epidemic. An economic model is overlaid upon this epidemiological model which facilitates comparison between new and existing technologies. A "Model runner" module allows for predictions of future disease burden trajectories under alternative scenario situations, as well as uncertainty, automatic calibration, cost-effectiveness and optimisation. The model has now been used to guide TB control strategies across a range of settings and countries, with our modular approach enabling repeated application of the tool without the need for extensive modification for each application. The modular construction of the platform minimises errors, enhances readability and collaboration between multiple programmers and enables rapid adaptation to answer questions in a broad range of contexts without the need for extensive re-programming. Such features are particularly important in simulating an epidemic as complex and diverse as TB.

Some studies on the behavior of W-RE thermocouple materials at high temperatures

NASA Technical Reports Server (NTRS)

Burns, G. W.; Hurst, W. S.

1972-01-01

Bare 0.25 mm diameter W-Re alloy thermoelements (W, W-3% Re, W-5% Re and W-25%) and BeO-insulated W-3% Re and W-25% Re thermoelements were examined for metallurgical, chemical and thermal emf changes after testing for periods up to 1000 hours at temperatures principally in the range 2000 to 2400 K. Environments for the tests consisted of high purity argon, hydrogen, helium or nitrogen gases. Commercially obtained bare-wire thermoelements typically exhibited a shift in their emf-temperature relationship upon initial exposure. The shift was completed by thermally aging the W-3% Re thermoelement for 1 hour and the W-25% Re thermoelement for 2 minutes at 2400 K in argon or hydrogen. Aged thermoelements experienced no appreciable drift with subsequent exposure at 2400 K in the gaseous environments. The chemically doped W3% Re thermoelement retained a small-grained structure for exposure in excess of 50 hours at 2400 K. BeO-insulated thermoelement assemblies showed varied behavior that depended upon the method of exposure. However, when the assemblies were heated in a furnace, no serious material incompatibility problems were found if the materials were given prior thermal treatments. Thermocouples, assembled from aged W-3% Re and W-25% Re thermoelements and degassed sintered BeO insulators, exhibited a drift of only 2 to 3 K during exposure in argon at 2070 K for 1029 hours.

System analysis study of space platform and station accommodations for life sciences research facilities. Volume 2: Study results, attachment 2. Phase A: Conceptual design and programmatics

NASA Technical Reports Server (NTRS)

Wiley, Lowell F.

1985-01-01

The study results from the conceptual design and programmatics segment of the Space Platform and Station Accommodation for Life Sciences Research Facilities. The results and significant findings of the conceptual design and programmatics were generated by these tasks: (1) the review and update engineering and science requirements; (2) analysis of life sciences mission transition scenario; (3) the review and update of key trade issues; (4) the development of conceptual definition and designs; and (5) the development of the work breakdown schedule and its dictionary, program schedule, and estimated costs.

System analysis study of space platform and station accommodations for life sciences research facilities. Volume 1: Executive summary. Phase A: Conceptual design and programmatics

NASA Technical Reports Server (NTRS)

1985-01-01

The study was conducted in 3 parts over a 3 year period. The study schedule and the documentation associated with each study part is given. This document summarized selected study results from the conceptual design and programmatics segment of the effort. The objectives were: (1) to update requirements and tradeoffs and develop a detailed design and mission requirements document; (2) to develop conceptual designs and mission descriptions; and (3) to develop programmatic, i.e., work breakdown structure and work breakdown structure dictionary, estimated cost, and implementing plans and schedules.

Palliative Care: The Relief You Need When You're Experiencing Symptoms of Serious Illness

MedlinePlus

... and can leave you lacking the energy or motivation to pursue the things you enjoy. They also ... palliative care team and your health care provider work together. Most clinicians appreciate the extra time and ...

Experience of violence and adverse reproductive health outcomes, HIV risks among mobile female sex workers in India

PubMed Central

2011-01-01

Background Female sex workers (FSWs) are a population sub-group most affected by the HIV epidemic in India and elsewhere. Despite research and programmatic attention to FSWs, little is known regarding sex workers' reproductive health and HIV risk in relation to their experiences of violence. This paper therefore aims to understand the linkages between violence and the reproductive health and HIV risks among a group of mobile FSWs in India. Methods Data are drawn from a cross-sectional behavioural survey conducted in 22 districts from four high HIV prevalence states (Andhra Pradesh, Karnataka, Maharashtra, Tamil Nadu) in India between September 2007 and July 2008. The survey sample included 5,498 FSWs who had moved to at least two different places for sex work in the past two years, and are classified as mobile FSWs in the current study. Analyses calculated the prevalence of past year experiences of violence; and adjusted logistic regression models examined the association between violence and reproductive health and HIV risks after controlling for background characteristics and program exposure. Results Approximately one-third of the total mobile FSWs (30.5%, n = 1,676) reported experiencing violence at least once in the past year; 11% reported experiencing physical violence, and 19.5% reported experiencing sexual violence. Results indicate that FSWs who had experienced any violence (physical or sexual) were significantly more likely to be vulnerable to both reproductive health and HIV risks. For example, FSWs who experienced violence were more likely than those who did not experience violence to have experienced a higher number of pregnancies (adjusted odds ratio [OR] = 1.2, 95% confidence interval [CI] = 1.0-1.6), ever experienced pregnancy loss (adjusted OR = 1.4, 95% CI = 1.2-1.6), ever experienced forced termination of pregnancy (adjusted OR = 2.4, 95% CI = 2.0-2.7), experienced multiple forced termination of pregnancies (adjusted OR = 2.2, 95% CI = 1.7-2.8), and practice inconsistent condom use currently (adjusted OR = 1.97, 95% CI: 1.4-2.0). Among FSWs who experienced violence, those who experienced sexual violence were more likely than those who had experienced physical violence to report inconsistent condom use (adjusted OR = 1.8, 95% CI: 1.4-2.3), and experience STI symptoms (adjusted OR = 1.3, 95% CI: 1.1-1.7). Conclusion The pervasiveness of violence and its association with reproductive health and HIV risk highlights that the abuse in general is an important determinant for reproductive health risks; and sexual violence is significantly associated with HIV risks among those who experienced violence. Existing community mobilization programs that have primarily focused on empowering FSWs should broaden their efforts to promote reproductive health in addition to the prevention of HIV among all FSWs, with particular emphasis on FSWs who experienced violence. PMID:21599984

Experience of violence and adverse reproductive health outcomes, HIV risks among mobile female sex workers in India.

PubMed

Swain, Suvakanta N; Saggurti, Niranjan; Battala, Madhusudana; Verma, Ravi K; Jain, Anrudh K

2011-05-20

Female sex workers (FSWs) are a population sub-group most affected by the HIV epidemic in India and elsewhere. Despite research and programmatic attention to FSWs, little is known regarding sex workers' reproductive health and HIV risk in relation to their experiences of violence. This paper therefore aims to understand the linkages between violence and the reproductive health and HIV risks among a group of mobile FSWs in India. Data are drawn from a cross-sectional behavioural survey conducted in 22 districts from four high HIV prevalence states (Andhra Pradesh, Karnataka, Maharashtra, Tamil Nadu) in India between September 2007 and July 2008. The survey sample included 5,498 FSWs who had moved to at least two different places for sex work in the past two years, and are classified as mobile FSWs in the current study. Analyses calculated the prevalence of past year experiences of violence; and adjusted logistic regression models examined the association between violence and reproductive health and HIV risks after controlling for background characteristics and program exposure. Approximately one-third of the total mobile FSWs (30.5%, n = 1,676) reported experiencing violence at least once in the past year; 11% reported experiencing physical violence, and 19.5% reported experiencing sexual violence. Results indicate that FSWs who had experienced any violence (physical or sexual) were significantly more likely to be vulnerable to both reproductive health and HIV risks. For example, FSWs who experienced violence were more likely than those who did not experience violence to have experienced a higher number of pregnancies (adjusted odds ratio [OR] = 1.2, 95% confidence interval [CI] = 1.0-1.6), ever experienced pregnancy loss (adjusted OR = 1.4, 95% CI = 1.2-1.6), ever experienced forced termination of pregnancy (adjusted OR = 2.4, 95% CI = 2.0-2.7), experienced multiple forced termination of pregnancies (adjusted OR = 2.2, 95% CI = 1.7-2.8), and practice inconsistent condom use currently (adjusted OR = 1.97, 95% CI: 1.4-2.0). Among FSWs who experienced violence, those who experienced sexual violence were more likely than those who had experienced physical violence to report inconsistent condom use (adjusted OR = 1.8, 95% CI: 1.4-2.3), and experience STI symptoms (adjusted OR = 1.3, 95% CI: 1.1-1.7). The pervasiveness of violence and its association with reproductive health and HIV risk highlights that the abuse in general is an important determinant for reproductive health risks; and sexual violence is significantly associated with HIV risks among those who experienced violence. Existing community mobilization programs that have primarily focused on empowering FSWs should broaden their efforts to promote reproductive health in addition to the prevention of HIV among all FSWs, with particular emphasis on FSWs who experienced violence.

Identifying Inputs to Leadership Development within an Interdisciplinary Leadership Minor

ERIC Educational Resources Information Center

McKim, Aaron J.; Sorensen, Tyson J.; Velez, Jonathan J.

2015-01-01

Researchers conducted a qualitative analysis of students' experiences while enrolled in an interdisciplinary leadership minor with the intent to determine programmatic inputs that spur leadership development. Based on students' reflections, three domains of programmatic inputs for leadership development within the minor were identified. These…

Program Directors' Perceptions of Programmatic Attributes Contributing to Athletic Training Student Persistence

ERIC Educational Resources Information Center

Bowman, Thomas G.; Dodge, Thomas M.; Mazerolle, Stephanie M.

2015-01-01

Context: Graduates of athletic training programs (ATPs) have identified factors contributing to their persistence through professional education. However, program directors have yet to elaborate on programmatic attributes that might contribute to athletic training student retention in their respective ATPs. Objective: To determine program…

76 FR 29217 - Notice of Availability of the Final Programmatic Environmental Impact Statement for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... Final Programmatic Environmental Impact Statement for the Mechanical and Artificial Creation and... Statement (FPEIS) for the Mechanical and Artificial Creation and Maintenance of Emergent Sandbar Habitat on... provide National Environmental Policy Act (NEPA) coverage for the mechanical and artificial construction...

ACHP | News

Science.gov Websites

Conservation Service Develops Prototype Programmatic Agreement That Can Give States More Time Savings and ) is pleased to announce it has designated a Prototype Programmatic Agreement (PA) for the use of the ) without the need for ACHP participation in consultation or execution of the agreement. This program

Solar Energy Development PEIS Information Center

Science.gov Websites

skip navigation Solar Energy Development Programmatic EIS Home About the EIS Public Involvement Solar Energy Solar Energy Zones Maps Documents secondary menu News Frequently Asked Questions Glossary E the Programmatic Environmental Impact Statement for Solar Energy Development in Six Southwestern

FY 2016 Grant Announcement: FY 2016 Technical Analysis and Programmatic Evaluation Support to the Chesapeake Bay Program Partnership

EPA Pesticide Factsheets

The U.S. Environmental Protection Agency’s Chesapeake Bay Program Office is announcing a Request for Proposals for applicants to provide the Chesapeake Bay Program partners with a proposal(s) for providing technical analysis and programmatic evaluation

The TPS Advanced Development Project for CEV

NASA Technical Reports Server (NTRS)

Reuther, James; Wercinski, Paul; Venkatapathy, Ethiraj; Ellerby, Don; Raiche, George; Bowman, Lynn; Jones, Craig; Kowal, John

2006-01-01

The CEV TPS Advanced Development Project (ADP) is a NASA in-house activity for providing two heatshield preliminary designs (a Lunar direct return as well as a LEO only return) for the CEV, including the TPS, the carrier structure, the interfaces and the attachments. The project s primary objective is the development of a single heatshield preliminary design that meets both Lunar direct return and LEO return requirements. The effort to develop the Lunar direct return capable heatshield is considered a high risk item for the NASA CEV development effort due to the low TRL (approx. 4) of the candidate TPS materials. By initiating the TPS ADP early in the development cycle, the intent is to use materials analysis and testing in combination with manufacturing demonstrations to reduce the programmatic risk of using advanced TPS technologies in the critical path for CEV. Due to the technical and schedule risks associated a Lunar return heatshield, the ADP will pursue a parallel path design approach, whereby a back-up TPS/heatshield design that only meets LEO return requirements is also developed. The TPS materials and carrier structure design concept selections will be based on testing, analysis, design and evaluation of scalability and manufacturing performed under the ADP. At the TPS PDR, the preferred programmatic strategy is to transfer the continued (detailed) design, development, testing and evaluation (DDT&E) of both the Lunar direct and LEO return designs to a government/prime contractor coordinated sub-system design team. The CEV prime contractor would have responsibility for the continued heatshield sub-system development. Continued government participation would include analysis, testing and evaluation as well as decision authority at TPS Final System Decision (FSD) (choosing between the primary and back-up heatshields) occurring between TPS PDR and TPS Critical Design Review (CDR). After TPS FSD the prime CEV contractor will complete the detailed design, certification testing, procurement, and integration of the CEV TPS.

Closing up Shop: Perspectives on the Departmental/Programmatic Elimination Experience

ERIC Educational Resources Information Center

Donoff, Susan B.; Rosser, Vicki J.

2016-01-01

Departmental and programmatic eliminations represent a new paradigm in the history of American higher education. Hastened by a national economic recession and competing state funding priorities, public postsecondary institutions have turned to academic attrition as a solution to continuous budgetary shortfalls. As a means of addressing the lived…

Closing up Shop: Meditations on the Departmental/Programmatic Elimination Experience

ERIC Educational Resources Information Center

Donoff, Susan Beth

2012-01-01

Departmental and programmatic eliminations represent a new paradigm in the history of American higher education. Hastened by a national economic recession and competing state funding priorities, public post-secondary institutions have turned to academic attrition as a solution to continuous budgetary shortfalls. As a means of addressing the lived…

76 FR 24050 - Coral Reef Restoration Plan, Final Programmatic Environmental Impact Statement, Biscayne National...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-29

... DEPARTMENT OF THE INTERIOR National Park Service [2310-0003-422] Coral Reef Restoration Plan... for the Coral Reef Restoration Plan, Biscayne National Park. SUMMARY: Pursuant to the National... availability of a Final Programmatic Environmental Impact Statement for the Coral Reef Restoration Plan (Plan...

78 FR 16275 - Extension of the Duration of Programmatic Agreements Based on the Department of Energy Prototype...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-14

... ADVISORY COUNCIL ON HISTORIC PRESERVATION Extension of the Duration of Programmatic Agreements... Comment AGENCY: Advisory Council on Historic Preservation. ACTION: The Advisory Council on Historic... Program, and Energy Efficiency and Conservation Block Grant. SUMMARY: The Advisory Council on Historic...

Student Retention in Higher Education: Some Conceptual and Programmatic Perspectives.

ERIC Educational Resources Information Center

Lang, Marvel

2002-01-01

Provides a review of conceptual perspectives on the salient issues affecting student retention in higher education generally, and minority student retention in particular, over the past few decades. Also summarizes programmatic strategies implemented at institutions as examples of student retention initiatives that have had significant impacts.…

75 FR 67084 - Notice of Availability of the Draft Programmatic Environmental Impact Statement for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-01

... Draft Programmatic Environmental Impact Statement for the Mechanical Creation and Maintenance of... the Mechanical Creation and Maintenance of Emergent Sandbar Habitat on the Riverine Segments of the... Environmental Impact Statement for the Mechanical Creation and Maintenance of Emergent Sandbar Habitat in the...

47 CFR Appendix B to Part 1 - Nationwide Programmatic Agreement for the Collocation of Wireless Antennas

Code of Federal Regulations, 2010 CFR

2010-10-01

... Collocation of Wireless Antennas B Appendix B to Part 1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... the Collocation of Wireless Antennas Nationwide Programmatic Agreement for the Collocation of Wireless Antennas Executed by the Federal Communications Commission, the National Conference of State Historic...

47 CFR Appendix B to Part 1 - Nationwide Programmatic Agreement for the Collocation of Wireless Antennas

Code of Federal Regulations, 2014 CFR

2014-10-01

... Collocation of Wireless Antennas B Appendix B to Part 1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... the Collocation of Wireless Antennas Nationwide Programmatic Agreement for the Collocation of Wireless Antennas Executed by the Federal Communications Commission, the National Conference of State Historic...

47 CFR Appendix B to Part 1 - Nationwide Programmatic Agreement for the Collocation of Wireless Antennas

Code of Federal Regulations, 2011 CFR

2011-10-01

... Collocation of Wireless Antennas B Appendix B to Part 1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... the Collocation of Wireless Antennas Nationwide Programmatic Agreement for the Collocation of Wireless Antennas Executed by the Federal Communications Commission, the National Conference of State Historic...

47 CFR Appendix B to Part 1 - Nationwide Programmatic Agreement for the Collocation of Wireless Antennas

Code of Federal Regulations, 2013 CFR

2013-10-01

... Collocation of Wireless Antennas B Appendix B to Part 1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... the Collocation of Wireless Antennas Nationwide Programmatic Agreement for the Collocation of Wireless Antennas Executed by the Federal Communications Commission, the National Conference of State Historic...

47 CFR Appendix B to Part 1 - Nationwide Programmatic Agreement for the Collocation of Wireless Antennas

Code of Federal Regulations, 2012 CFR

2012-10-01

... Collocation of Wireless Antennas B Appendix B to Part 1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... the Collocation of Wireless Antennas Nationwide Programmatic Agreement for the Collocation of Wireless Antennas Executed by the Federal Communications Commission, the National Conference of State Historic...

77 FR 59395 - Grand River Dam Authority; Notice of Revised Restricted Service List for a Programmatic Agreement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-27

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2524-018--Oklahoma Salina Pumped Storage Project] Grand River Dam Authority; Notice of Revised Restricted Service List for a Programmatic Agreement Rule 2010 of the Federal Energy Regulatory Commission's (Commission) Rules of Practice...

20 CFR 645.210 - What is meant by the terms “entity” and “project” in the statutory phrase “an entity that...

Code of Federal Regulations, 2010 CFR

2010-04-01

... programmatic, supported by the total amount of one discrete award of WtW Governors' funds for long-term... programmatic, supported by the total amount of one discrete WtW competitive grant awarded to the entity...

Uranium Leasing Program PEIS Information Center

Science.gov Websites

Search Go search Uranium Leasing Program Programmatic Environmental Impact Statement Information Center Environmental Impact Statement (PEIS) for the Uranium Leasing Program. The United States Department of Energy (DOE) Office of Legacy Management (LM) has prepared a Programmatic Environmental Impact Statement (PEIS

77 FR 43808 - Supplement to the Draft Programmatic Restoration Plan and Programmatic Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce... Liability Act of 1980 (CERCLA), the Oil Pollution Act (OPA) of 1990, the Clean Water Act (CWA), the National Oil and Hazardous Substances Pollution Contingency Plan (National Contingency Plan [NCP]), and other...

78 FR 25702 - Notice of Availability of a Draft Programmatic Environmental Assessment for Fisheries Research...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-02

... Availability of a Draft Programmatic Environmental Assessment for Fisheries Research Conducted and Funded by... Research Conducted and Funded by the Southwest Fisheries Science Center (SWFSC).'' Publication of this... cumulative impacts of conducting and funding fisheries and ecosystem research along the U.S. West Coast...

77 FR 39686 - Draft Programmatic Environmental Impact Statement and Restoration Plan To Compensate for Injuries...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-05

... Programmatic Environmental Impact Statement and Restoration Plan To Compensate for Injuries to Natural... Environmental Impact Statement and Restoration Plan; request for comments. SUMMARY: NOAA, the Department of the... Statement (PEIS) and Draft Restoration Plan are being released for public comment. The Restoration Plan...

75 FR 26269 - Draft Programmatic Environmental Assessment for the Integrated Public Alert and Warning Program's...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

...] Draft Programmatic Environmental Assessment for the Integrated Public Alert and Warning Program's... from construction- related actions taken under the Integrated Public Alert and Warning Program (IPAWS... Order 13407, Public Alert and Warning System, by providing robust and survivable power generation, fuel...

36 CFR 800.13 - Post-review discoveries.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Post-review discoveries. 800... PROTECTION OF HISTORIC PROPERTIES The section 106 Process § 800.13 Post-review discoveries. (a) Planning for subsequent discoveries—(1) Using a programmatic agreement. An agency official may develop a programmatic...

36 CFR § 800.13 - Post-review discoveries.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Post-review discoveries. Â... PROTECTION OF HISTORIC PROPERTIES The section 106 Process § 800.13 Post-review discoveries. (a) Planning for subsequent discoveries—(1) Using a programmatic agreement. An agency official may develop a programmatic...

36 CFR 800.13 - Post-review discoveries.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Post-review discoveries. 800... PROTECTION OF HISTORIC PROPERTIES The section 106 Process § 800.13 Post-review discoveries. (a) Planning for subsequent discoveries—(1) Using a programmatic agreement. An agency official may develop a programmatic...

36 CFR 800.13 - Post-review discoveries.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Post-review discoveries. 800... PROTECTION OF HISTORIC PROPERTIES The section 106 Process § 800.13 Post-review discoveries. (a) Planning for subsequent discoveries—(1) Using a programmatic agreement. An agency official may develop a programmatic...

36 CFR 800.13 - Post-review discoveries.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Post-review discoveries. 800... PROTECTION OF HISTORIC PROPERTIES The section 106 Process § 800.13 Post-review discoveries. (a) Planning for subsequent discoveries—(1) Using a programmatic agreement. An agency official may develop a programmatic...

78 FR 21919 - Finding of No Significant Impact and Final Programmatic Environmental Assessment for Army 2020...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-12

... Programmatic Environmental Assessment for Army 2020 Force Structure Realignment AGENCY: Department of the Army... of the Finding of No Significant Impact (FNSI) for implementation of force structure realignment to... Structure Realignment (PEA), supporting studies, and comments received during the public review period, the...

Highlights of Programmatic, Interdisciplinary Research on Writing

ERIC Educational Resources Information Center

Berninger, Virginia W.

2009-01-01

An overview of research topics and findings from an interdisciplinary, programmatic line of research on writing over the past 25 years is presented. The cross-sectional assessment studies (grades 1 to 9) showed which measures uniquely explained variance in handwriting, spelling, and composing and thus validated their use in assessment. These and…

Leadership Development: An Examination of Individual and Programmatic Growth

ERIC Educational Resources Information Center

Conner, Jerusha Osberg; Strobel, Karen

2007-01-01

This study focuses on two girls' experiences in one youth leadership organization during a period of 3 years. Relying on an embedded case study design, the authors examine the links between leadership development and programmatic structures and supports. Specifically, the development of leadership capacities are analyzed along three dimensions:…

76 FR 53994 - Final Environmental Impact Statement, Single Nuclear Unit at the Bellefonte Plant Site, Jackson...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... Programmatic Environmental Impact Statement (December 1995) and Reservoir Operations Study Final Programmatic.... Completion and operation of the 1,260-MW Bellefonte Unit 1 was one of the resource options analyzed in the..., Completion and Operation of Bellefonte Unit 1, as TVA's [[Page 53995

Satellite Power Systems (SPS) concept definition study (Exhibit D). Volume 4, Part 2: Cost and programmatics appendix

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1981-01-01

Cost and programmatic aspects of a recommended satellite power system are documented. Computer generated summaries are presented, and the detailed computer runs structured in a Work Breakdown Structure are given. The six configurations developed during the study period are summarized.

75 FR 62433 - Notice of Public Hearings and the Availability of a Draft Programmatic Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

... NATIONAL SCIENCE FOUNDATION Notice of Public Hearings and the Availability of a Draft Programmatic Environmental Impact Statement/Overseas Environmental Impact Statement (PEIS/OEIS) AGENCY: National Science... Seismic Research Funded by the National Science Foundation (NSF) or Conducted by the U.S. Geological...

77 FR 13095 - Intent To Prepare an Environmental Impact Statement for NOAA Restoration Center Programmatic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... Coastal Wetland Planning, Protection and Restoration Act (CWPPRA) Program, and the Great Lakes Habitat... Prepare an Environmental Impact Statement for NOAA Restoration Center Programmatic Coastal Habitat... (PEIS) to evaluate the potential environmental impacts of different ranges of coastal and marine habitat...

Programmatic Factors Associated with Undergraduate Athletic Training Student Retention and Attrition Decisions

ERIC Educational Resources Information Center

Bowman, Thomas G.; Hertel, Jay; Wathington, Heather D.

2015-01-01

Context: Athletic training programs (ATPs) are charged with meeting an increased demand for athletic trainers with adequate graduates. Currently, the retention rate of athletic training students in ATPs nationwide and the programmatic factors associated with these retention rates remain unknown. Objective: Determine the retention rate for athletic…

Toward Programmatic Research on Virtue Assessment: Challenges and Prospects

ERIC Educational Resources Information Center

Fowers, Blaine J.

2014-01-01

Poor construct definition has characterized research on virtue, beginning with Hartshorne and May's honesty studies and continuing to the present. Recently, scholars have begun to define virtues in ways that improve the prospects for measuring virtue constructs, but a coordinated, programmatic approach is necessary for success in virtue…

Analysis of re-replication from deregulated origin licensing by DNA fiber spreading

PubMed Central

Dorn, Elizabeth S.; Chastain, Paul D.; Hall, Jonathan R.; Cook, Jeanette Gowen

2009-01-01

A major challenge each human cell-division cycle is to ensure that DNA replication origins do not initiate more than once, a phenomenon known as re-replication. Acute deregulation of replication control ultimately causes extensive DNA damage, cell-cycle checkpoint activation and cell death whereas moderate deregulation promotes genome instability and tumorigenesis. In the absence of detectable increases in cellular DNA content however, it has been difficult to directly demonstrate re-replication or to determine if the ability to re-replicate is restricted to a particular cell-cycle phase. Using an adaptation of DNA fiber spreading we report the direct detection of re-replication on single DNA molecules from human chromosomes. Using this method we demonstrate substantial re-replication within 1 h of S phase entry in cells overproducing the replication factor, Cdt1. Moreover, a comparison of the HeLa cancer cell line to untransformed fibroblasts suggests that HeLa cells produce replication signals consistent with low-level re-replication in otherwise unperturbed cell cycles. Re-replication after depletion of the Cdt1 inhibitor, geminin, in an untransformed fibroblast cell line is undetectable by standard assays but readily quantifiable by DNA fiber spreading analysis. Direct evaluation of re-replicated DNA molecules will promote increased understanding of events that promote or perturb genome stability. PMID:19010964

Discrete Mathematics Re "Tooled."

ERIC Educational Resources Information Center

Grassl, Richard M.; Mingus, Tabitha T. Y.

1999-01-01

Indicates the importance of teaching discrete mathematics. Describes how the use of technology can enhance the teaching and learning of discrete mathematics. Explorations using Excel, Derive, and the TI-92 proved how preservice and inservice teachers experienced a new dimension in problem solving and discovery. (ASK)

New tools and methods for direct programmatic access to the dbSNP relational database.

PubMed

Saccone, Scott F; Quan, Jiaxi; Mehta, Gaurang; Bolze, Raphael; Thomas, Prasanth; Deelman, Ewa; Tischfield, Jay A; Rice, John P

2011-01-01

Genome-wide association studies often incorporate information from public biological databases in order to provide a biological reference for interpreting the results. The dbSNP database is an extensive source of information on single nucleotide polymorphisms (SNPs) for many different organisms, including humans. We have developed free software that will download and install a local MySQL implementation of the dbSNP relational database for a specified organism. We have also designed a system for classifying dbSNP tables in terms of common tasks we wish to accomplish using the database. For each task we have designed a small set of custom tables that facilitate task-related queries and provide entity-relationship diagrams for each task composed from the relevant dbSNP tables. In order to expose these concepts and methods to a wider audience we have developed web tools for querying the database and browsing documentation on the tables and columns to clarify the relevant relational structure. All web tools and software are freely available to the public at http://cgsmd.isi.edu/dbsnpq. Resources such as these for programmatically querying biological databases are essential for viably integrating biological information into genetic association experiments on a genome-wide scale.

Geothermal Program Review VI: proceedings. Beyond goals and objectives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

Program Review VI was comprised of six sessions, including an opening session, four technical sessions that addressed each of the major DOE research areas, and a session on special issues. The technical sessions were on Hydrothermal, Hot Dry Rock, Geopressured and Magma resources. Presenters in the technical sessions discussed their R and D activities within the context of specific GTD Programmatic Objectives for that technology, their progress toward achieving those objectives, and the value of those achievements to industry. The ''Special Issues'' presentations addressed several topics such as the interactions between government and industry on geothermal energy R and D;more » the origin and basis for the programmatic objectives analytical computer model; and international marketing opportunities for US geothermal equipment and services. The unique aspect of Program Review VI was that it was held in conjunction with the National Geothermal Association's Industry Round Table on Federal R and D. The Round Table provided a forum for open and lively discussions between industry and government researchers and gave industry an opportunity to convey their needs and perspectives on DOE's research programs. These discussions also provided valuable information to DOE regarding industry's priorities and directions.« less

Electronic band structure of ReS2 by high-resolution angle-resolved photoemission spectroscopy

NASA Astrophysics Data System (ADS)

Webb, James L.; Hart, Lewis S.; Wolverson, Daniel; Chen, Chaoyu; Avila, Jose; Asensio, Maria C.

2017-09-01

The rhenium-based transition metal dichalcogenides (TMDs) are atypical of the TMD family due to their highly anisotropic crystalline structure and are recognized as promising materials for two-dimensional heterostructure devices. The nature of the band gap (direct or indirect) for bulk, few-, and single-layer forms of ReS2 is of particular interest, due to its comparatively weak interplanar interaction. However, the degree of interlayer interaction and the question of whether a transition from indirect to direct gap is observed on reducing thickness (as in other TMDs) are controversial. We present a direct determination of the valence band structure of bulk ReS2 using high-resolution angle-resolved photoemission spectroscopy. We find a clear in-plane anisotropy due to the presence of chains of Re atoms, with a strongly directional effective mass which is larger in the direction orthogonal to the Re chains (2.2 me ) than along them (1.6 me ). An appreciable interplane interaction results in an experimentally measured difference of ≈100 -200 meV between the valence band maxima at the Z point (0,0,1/2 ) and the Γ point (0,0,0) of the three-dimensional Brillouin zone. This leads to a direct gap at Z and a close-lying but larger gap at Γ , implying that bulk ReS2 is marginally indirect. This may account for recent conflicting transport and photoluminescence measurements and the resulting uncertainty about the nature of the band gap in this material.

Current directions in military health-care provider resilience.

PubMed

Lester, Paul B; Taylor, Lauren C; Hawkins, Stacy Ann; Landry, Lisa

2015-02-01

After more than a decade of war, the US military continues to place significant emphasis on psychological health and resilience. While research and programs that focus on the broader military community's resilience continue to emerge, less is known about and until recently little focus has been placed on military medical provider resilience. In this article, we review the literature on military medical provider resilience, provide an overview of the programmatic and technological advances designed to sustain and develop military medical provider resilience, and finally offer recommendations for future research.

Climate Dynamics and Experimental Prediction (CDEP) and Regional Integrated Science Assessments (RISA) Programs at NOAA Office of Global Programs

NASA Astrophysics Data System (ADS)

Bamzai, A.

2003-04-01

This talk will highlight science and application activities of the CDEP and RISA programs at NOAA OGP. CDEP, through a set of Applied Research Centers (ARCs), supports NOAA's program of quantitative assessments and predictions of global climate variability and its regional implications on time scales of seasons to centuries. The RISA program consolidates results from ongoing disciplinary process research under an integrative framework. Examples of joint CDEP-RISA activities will be presented. Future directions and programmatic challenges will also be discussed.

Roles of inter-individual differences and intra-individual acute elevations in early smoking lapse in people with posttraumatic stress disorder.

PubMed

Dedert, Eric A; Hicks, Terrell A; Dennis, Paul A; Calhoun, Patrick S; Beckham, Jean C

2016-09-01

Existing models of the role of posttraumatic stress disorder (PTSD) symptoms and smoking have almost exclusively examined mean symptom levels, rather than the acute elevations that might trigger smoking lapse immediately or increase risk of a smoking lapse in the next few hours. We examined ecological momentary assessments (EMA) of PTSD symptom clusters and smoking in the first week of a quit attempt in 52 people with PTSD. In multilevel models including PTSD symptom means, acute elevations, and lagged acute elevations together as simultaneous predictors of odds of smoking in the same models, pre-quit smoking occasions were significantly related to acute elevations in symptoms, including PTSD totals (OR=1.20; 95% CI, 1.10 to 1.31), PTSD re-experiencing symptoms (OR=1.16; 95% CI, 1.06 to 1.27), PTSD avoidance symptoms (OR=1.20; 95% CI, 1.10 to 1.31), PTSD numbing symptoms (OR=1.14; 95% CI, 1.04 to 1.24), and PTSD hyperarousal symptoms (OR=1.20; 95% CI, 1.09 to 1.31). In contrast, post-quit smoking was related to lagged acute elevations in PTSD re-experiencing (OR=1.24, 95% CI, 1.03 to 1.50) avoidance (OR=1.27, 95% CI, 1.05 to 1.53), and numbing symptoms (OR=1.24, 95% CI, 1.02 to 1.51). During a quit attempt, individuals with PTSD delayed smoking in response to acute elevations in PTSD re-experiencing and Avoidance. This period presents an opportunity to use mobile health interventions to prevent smoking lapse and to use coping skills acquired in trauma-focused therapy to respond to acute PTSD symptom elevation. Published by Elsevier Ltd.

BioServices: a common Python package to access biological Web Services programmatically.

PubMed

Cokelaer, Thomas; Pultz, Dennis; Harder, Lea M; Serra-Musach, Jordi; Saez-Rodriguez, Julio

2013-12-15

Web interfaces provide access to numerous biological databases. Many can be accessed to in a programmatic way thanks to Web Services. Building applications that combine several of them would benefit from a single framework. BioServices is a comprehensive Python framework that provides programmatic access to major bioinformatics Web Services (e.g. KEGG, UniProt, BioModels, ChEMBLdb). Wrapping additional Web Services based either on Representational State Transfer or Simple Object Access Protocol/Web Services Description Language technologies is eased by the usage of object-oriented programming. BioServices releases and documentation are available at http://pypi.python.org/pypi/bioservices under a GPL-v3 license.

Progressing from programmatic to discovery research: a case example with the overjustification effect.

PubMed

Roane, Henry S; Fisher, Wayne W; McDonough, Erin M

2003-01-01

Scientific research progresses along planned (programmatic research) and unplanned (discovery research) paths. In the current investigation, we attempted to conduct a single-case evaluation of the overjustification effect (i.e., programmatic research). Results of the initial analysis were contrary to the overjustification hypothesis in that removal of the reward contingency produced an increase in responding. Based on this unexpected finding, we conducted subsequent analyses to further evaluate the mechanisms underlying these results (i.e., discovery research). Results of the additional analyses suggested that the reward contingency functioned as punishment (because the participant preferred the task to the rewards) and that withdrawal of the contingency produced punishment contrast.

Progressing from programmatic to discovery research: a case example with the overjustification effect.

PubMed Central

Roane, Henry S; Fisher, Wayne W; McDonough, Erin M

2003-01-01

Scientific research progresses along planned (programmatic research) and unplanned (discovery research) paths. In the current investigation, we attempted to conduct a single-case evaluation of the overjustification effect (i.e., programmatic research). Results of the initial analysis were contrary to the overjustification hypothesis in that removal of the reward contingency produced an increase in responding. Based on this unexpected finding, we conducted subsequent analyses to further evaluate the mechanisms underlying these results (i.e., discovery research). Results of the additional analyses suggested that the reward contingency functioned as punishment (because the participant preferred the task to the rewards) and that withdrawal of the contingency produced punishment contrast. PMID:12723865

Developing Educational Leaders for Social Justice: Programmatic Elements that Work or Need Improvement

ERIC Educational Resources Information Center

Guerra, Patricia L.; Nelson, Sarah W.; Jacobs, Jennifer; Yamamura, Erica

2013-01-01

In this qualitative study, Brown's (2004) tripartite theoretical framework on leadership preparation was used to explore the role programmatic elements played in development as social justice leaders within an educational leadership preparation program located in the United States. Findings from focus groups with twelve former graduate students…

Volunteer Middle Managers: Human Resources That Extend Programmatic Outreach

ERIC Educational Resources Information Center

Cassill, Heather; Culp, Ken, III; Hettmansperger, Jay; Stillwell, Marla; Sublet, Amanda

2012-01-01

Extension professionals must be able to give volunteers programmatic ownership, resources, and the education needed to complete tasks. However, resources such as time and money are limited, especially in economic downtimes, making it even more necessary to look at creative ways to bridge the gap between what programs and services can and should be…

U.S. Comparative and International Graduate Programs: An Overview of Programmatic Size, Relevance, Philosophy, and Methodology

ERIC Educational Resources Information Center

Drake, Timothy A.

2011-01-01

Previous work has concentrated on the epistemological foundation of comparative and international education (CIE) graduate programs. This study focuses on programmatic size, philosophy, methodology, and pedagogy. It begins by reviewing previous studies. It then provides a theoretical framework and describes the size, relevance, content, and…

Text Analysis of Chemistry Thesis and Dissertation Titles

ERIC Educational Resources Information Center

Scalfani, Vincent F.

2017-01-01

Programmatic text analysis can be used to understand patterns and reveal trends in data that would otherwise be difficult or impossible to uncover with manual coding methods. This work uses programmatic text analysis, specifically term frequency counts, to study nearly 10,000 chemistry thesis and dissertation titles from 1911-2015. The thesis and…

76 FR 42121 - Final Notice of a Finding of No Significant Impact for a Programmatic Environmental Assessment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-18

... for a Programmatic Environmental Assessment Implementing a Wind Energy Program at Marine Forces... Wind Energy Program at Marine Forces Reserve (MARFORRES) Facilities Located Across the United States... final notice that the FONSI for the PEA implementing the MARFORRES Wind Energy Program will not have a...

76 FR 53422 - Notice of Availability of the Record of Decision on the Final Programmatic Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... DEPARTMENT OF DEFENSE Department of the Army; Corps of Engineers Notice of Availability of the Record of Decision on the Final Programmatic Environmental Impact Statement for the Mechanical and... (PEIS) for the Mechanical and Artificial Creation and Maintenance of Emergent Sandbar Habitat (ESH) on...

76 FR 33270 - Cancellation of the Notice of Intent To Prepare a Programmatic Environmental Impact Statement for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

... scale and stage of geothermal energy development at Superstition Mountain on Naval Air Facility El... geothermal energy program needs at Naval Air Facility El Centro. Should geothermal development be indicated... Programmatic Environmental Impact Statement for the Proposed Geothermal Development Program, Naval Air Facility...

75 FR 29357 - Notice of Availability of the Draft Programmatic Environmental Assessment for the Deployment and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-25

... technology that is used to aid in inspecting high-density cargo containers for contraband such as illicit... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Notice of Availability of the Draft Programmatic Environmental Assessment for the Deployment and Operation of High Energy X-Ray...

ACHP | News | ACHP and Department of Energy Streamline Section 106 Process

Science.gov Websites

Energy The ACHP and DOE are providing a prototype Programmatic Agreement for dealing with historic properties as part of Recovery Act projects. Press Release (PDF) Protoype Programmatic Agreement (PDF) When DOE approves the use of an existing state interagency agreement for Section 106 compliance purposes in

ACHP | Nationwide Programmatic Agreements

Science.gov Websites

no longer in effect. The ACHP has notified each Federal agency with expired or superseded PAs of our findings. The list (below), Nationwide Programmatic Agreements In Effect as of March 2006, represents the remaining PAs, some of which were executed prior to revisions to the ACHP regulations that went into effect

Assessing Technical Writing in Institutional Contexts: Using Outcomes-Based Assessment for Programmatic Thinking.

ERIC Educational Resources Information Center

Carter, Michael; Anson, Chris M.; Miller, Carolyn R.

2003-01-01

Notes that technical writing instruction often operates in isolation from other components of students' communication education. Argues for altering this isolation by moving writing instruction to a place of increased programmatic perspective, which may be attained through a means of assessment based on educational outcomes. Discusses two models…

77 FR 44267 - Notice of Availability of the Final Programmatic Environmental Impact Statement for Solar Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-27

... Final EIS NOA and use them to inform the Records of Decision. Those individuals wishing to submit... general information regarding the DOE NEPA process, contact Carol Borgstrom, Director, Office of NEPA... development. Through the Final Programmatic EIS, the BLM is considering replacing elements of its existing...

76 FR 18547 - Grand River Dam Authority, Salina Pumped Storage Project; Notice of Proposed Restricted Service...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

... Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the National Register... Programmatic Agreement for managing properties included in, or eligible for inclusion in, the National Register... the official service list for the above-captioned proceedings may request inclusion on the restricted...

76 FR 63921 - Central Vermont Public Service Corporation; Notice of Proposed Restricted Service List for a...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-14

... Service List for a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in... a programmatic agreement for managing properties included in, or eligible for inclusion in, the... list for the above-captioned proceeding may request inclusion on the restricted service list, or may...

75 FR 78237 - Notice of Proposed Restricted Service List for a Programmatic Agreement for Managing Properties...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-15

... List for a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the... managing properties included in, or eligible for inclusion in, the National Register of Historic Places at... the above-captioned proceedings may request inclusion on the restricted service list, or may request...

75 FR 37432 - Marseilles Land and Water Company; Marseilles Lock and Dam Project; Notice of Proposed Restricted...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

... List for a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the... a programmatic agreement for managing properties included in, or eligible for inclusion in, the... official service list for the above-captioned proceeding may request inclusion on the restricted service...

77 FR 76474 - Extension of Public Review and Comment Period for the Draft Programmatic Environmental Assessment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... Nuclear Security Administration (NNSA) Web site at: http://www.nnsa.energy.gov/nepa . Comments on the... DEPARTMENT OF ENERGY Extension of Public Review and Comment Period for the Draft Programmatic...: Department of Energy. ACTION: Extension of public review and comment period. SUMMARY: On December 12, 2012...

77 FR 73996 - Notice of Availability for the Draft Programmatic Environmental Assessment for the Recycling of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-12

... for the Recycling of Scrap Metals Originating From Radiological Areas AGENCY: Department of Energy... public review and comment of the Draft Programmatic Environmental Assessment (PEA) for the Recycling of... procedures). This Draft PEA for the Recycling of Scrap Metals Originating from Radiological Areas analyzes...

77 FR 19307 - Renewal of Information Collection; OMB Control Number 1040-0001, DOI Programmatic Clearance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... Number 1040-0001, DOI Programmatic Clearance for Customer Satisfaction Surveys AGENCY: Department of the... Customer Satisfaction Surveys'' in your email subject line. Include your name and return address in your... accountability by promoting a new focus on results, service quality, and customer satisfaction.'' In order to...

Online Course Design in a Programmatic Framework: A Case from Social Work

ERIC Educational Resources Information Center

Stewart, Patricia Lynn

2014-01-01

The focus of this study centers on the way instructors, and more specifically, instructors within a programmatic initiative, think about teaching and the decision-making process they employ to design learning experiences for an online environment. Often administrative initiatives do not consider the unique individual instructor needs when planning…

An Empirical Typology of the Latent Programmatic Structure of Community College Student Success Programs

ERIC Educational Resources Information Center

Hatch, Deryl K.; Bohlig, E. Michael

2016-01-01

The definition and description of student success programs in the literature (e.g., orientation, first-year seminars, learning communities, etc.) suggest underlying programmatic similarities. Yet researchers to date typically depend on ambiguous labels to delimit studies, resulting in loosely related but separate research lines and few…

78 FR 15039 - Extending Scoping Period To Prepare a Programmatic Environmental Impact Statement (EIS) for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Extending Scoping Period To Prepare a Programmatic Environmental Impact Statement (EIS) for the Navajo Nation Integrated Weed Management Plan Within... Integrated Weed Management Plan on the Navajo Indian Reservation. DATES: Scoping comments are due on March 20...

34 CFR 611.52 - What are a grantee's programmatic responsibilities for ensuring that scholarship recipients...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.52 What are... 34 Education 3 2010-07-01 2010-07-01 false What are a grantee's programmatic responsibilities for...

A theoretical analysis of anatomical and functional intestinal slow wave re-entry.

PubMed

Du, Peng; O'Grady, Gregory; Cheng, Leo K

2017-07-21

Intestinal bioelectrical slow waves are a key regulator of intestinal motility. Peripheral pacemakers, ectopic initiations and sustained periods of re-entrant activities have all been experimentally observed to be important factors in setting the frequency of intestinal slow waves, but the tissue-level mechanisms underpinning these activities are unclear. This theoretical analysis aimed to define the initiation, maintenance, and termination criteria of two classes of intestinal re-entrant activities: anatomical re-entry and functional re-entry. Anatomical re-entry was modeled in a three-dimensional (3D) cylindrical model, and functional rotor was modeled in a 2D rectangle model. A single-pulse stimulus was used to invoke an anatomical re-entry and a prolonged refractory block was used to invoke the rotor. In both cases, the simulated re-entrant activities operated at frequencies above the baseline entrainment frequency. The anatomical re-entry simulation results demonstrated that a temporary functional refractory block would be required to initiate the re-entrant activity in a single direction around the cylindrical model. The rotor could be terminated by a single-pulse stimulus delivered around the core of the rotor. In conclusion, the simulation results provide the following new insights into the mechanisms of intestinal re-entry: (i) anatomical re-entry is only maintained within a specific range of velocities, outside of which the re-entrant activities become either an ectopic activity or simultaneous activations of the intestinal wall; (ii) a maintained rotor entrained slow waves faster in the antegrade direction than in the retrograde direction. Simulations are shown to be a valuable tool for achieving novel insights into the mechanisms of intestinal slow wave dysrhythmia. Copyright © 2017 Elsevier Ltd. All rights reserved.

Psychosocial Determinants of Chronic Stress in Nursing

DTIC Science & Technology

1987-12-22

registered nurses with current licenses were unemployed and that only 3% of the unemployed registered nurses were looking for jobs in the field of...characteristic symptoms involve a re-experiencing of the traumatic event (intrusive recollections of the event, dreams or nightmares) and psychic numbing

Intrusive trauma recollections is associated with impairment of interference inhibition and psychomotor speed in PTSD.

PubMed

Kertzman, Semion; Avital, Avi; Weizman, Abraham; Segal, Michael

2014-10-01

Intrusive cognitions that enter consciousness involuntarily are prominent symptoms of posttraumatic stress disorder (PTSD). The present study aimed to identify neuropsychological mechanisms involved. Fifty PTSD outpatients and 50 healthy controls were tested using Finger Tapping, Simple and Choice Reaction Times and Stroop Tasks, to measure motor, psychomotor speed, response selection, and interference inhibition ability respectively. PTSD patients performed poorly in all tests, presumably owing to their generalized slowness of information processing and motor reaction. Psychomotor speed was a predictor of slowness and high error rate during the Stroop. Impaired inhibition, as measured by the interference index of the Stroop task, explained 9.7% of the predicated variance in frequency of re-experiencing PTSD symptoms and 23.5% of the predicated variance in augmentation of the interference response time. Impaired interference control may be related to internal (re-experiencing) and external (sensory) stimuli that leads to cognitive deficits in PTSD patients. Copyright © 2014 Elsevier Inc. All rights reserved.

Unconventional Consumption Methods and Enjoying Things Consumed: Recapturing the "First-Time" Experience.

PubMed

O'Brien, Ed; Smith, Robert W

2018-06-01

People commonly lament the inability to re-experience familiar things as they were first experienced. Four experiments suggest that consuming familiar things in new ways can disrupt adaptation and revitalize enjoyment. Participants better enjoyed the same familiar food (Experiment 1), drink (Experiment 2), and video (Experiments 3a-3b) simply when re-experiencing the entity via unusual means (e.g., eating popcorn using chopsticks vs. hands). This occurs because unconventional methods invite an immersive "first-time" perspective on the consumption object: boosts in enjoyment were mediated by revitalized immersion into the consumption experience and were moderated by time such that they were strongest when using unconventional methods for the first time (Experiments 1-2); likewise, unconventional methods that actively disrupted immersion did not elicit the boost, despite being novel (Experiments 3a-3b). Before abandoning once-enjoyable entities, knowing to consume old things in new ways (vs. attaining new things altogether) might temporarily restore enjoyment and postpone wasteful replacement.

A review of current evidence regarding the ICD-11 proposals for diagnosing PTSD and complex PTSD.

PubMed

Brewin, Chris R; Cloitre, Marylène; Hyland, Philip; Shevlin, Mark; Maercker, Andreas; Bryant, Richard A; Humayun, Asma; Jones, Lynne M; Kagee, Ashraf; Rousseau, Cécile; Somasundaram, Daya; Suzuki, Yuriko; Wessely, Simon; van Ommeren, Mark; Reed, Geoffrey M

2017-12-01

The World Health Organization's proposals for posttraumatic stress disorder (PTSD) in the 11th edition of the International Classification of Diseases, scheduled for release in 2018, involve a very brief set of symptoms and a distinction between two sibling disorders, PTSD and Complex PTSD. This review of studies conducted to test the validity and implications of the diagnostic proposals generally supports the proposed 3-factor structure of PTSD symptoms, the 6-factor structure of Complex PTSD symptoms, and the distinction between PTSD and Complex PTSD. Estimates derived from DSM-based items suggest the likely prevalence of ICD-11 PTSD in adults is lower than ICD-10 PTSD and lower than DSM-IV or DSM-5 PTSD, but this may change with the development of items that directly measure the ICD-11 re-experiencing requirement. Preliminary evidence suggests the prevalence of ICD-11 PTSD in community samples of children and adolescents is similar to DSM-IV and DSM-5. ICD-11 PTSD detects some individuals with significant impairment who would not receive a diagnosis under DSM-IV or DSM-5. ICD-11 CPTSD identifies a distinct group who have more often experienced multiple and sustained traumas and have greater functional impairment than those with PTSD. Copyright © 2017 Elsevier Ltd. All rights reserved.

Examining the ethico-legal aspects of the right to refuse treatment in Turkey.

PubMed

Sert, Gurkan; Guven, Tolga

2013-10-01

This paper examines the ethico-legal problems regarding the right to refuse treatment in Turkey's healthcare system. We discuss these problems in the light of a recent case that was directly reported to us. We first summarise the experience of a chronically dependent patient (as recounted by her daughter) and her family during their efforts to refuse treatment and receive palliative care only. This is followed by a summary of the legal framework governing the limits of the right to refuse treatment in Turkey. With the help of this background information on the legal framework, we re-examine the ethico-legal aspects of the case and explain the underlying reasons for the problems the family and the patient experienced. Finally, we conclude that Turkey's legal framework relating to the right to refuse treatment needs to be clarified and amended in accordance with international conventions and fundamental human rights.

The effect of social networks and social support on common mental disorders following specific life events.

PubMed

Maulik, P K; Eaton, W W; Bradshaw, C P

2010-08-01

This study examined the association between life events and common mental disorders while accounting for social networks and social supports. Participants included 1920 adults in the Baltimore Epidemiologic Catchment Area Cohort who were interviewed in 1993-1996, of whom 1071 were re-interviewed in 2004-2005. Generalized estimating equations were used to analyze the data. Social support from friends, spouse or relatives was associated with significantly reduced odds of panic disorder and psychological distress, after experiencing specific life events. Social networks or social support had no significant stress-buffering effect. Social networks and social support had almost no direct or buffering effect on major depressive disorder, and no effect on generalized anxiety disorder and alcohol abuse or dependence disorder. The significant association between social support and psychological distress, rather than diagnosable mental disorders, highlights the importance of social support, especially when the severity of a mental health related problem is low.

Terrorism, post-traumatic stress, coping strategies, and spiritual outcomes.

PubMed

Meisenhelder, Janice Bell; Marcum, John P

2009-03-01

This mail survey measured post-traumatic stress symptoms, spiritual and non-spiritual coping strategies, and positive spiritual outcomes following the tragedies of 9/11/01 in a national, random sample of 1,056 Presbyterians. Respondents reported mild to moderate degrees of re-experiencing and hyper-arousal symptoms of post-traumatic stress, unrelated to location or knowing someone involved. People experiencing high stress used greater frequency and variety of both spiritual and non-spiritual types of coping strategies. Positive spiritual outcomes were remarkably related to positive spiritual coping strategies, in contrast to no association with negative coping. This study illustrates the significant degree of post-traumatic stress experienced with vicarious exposure and a wide spectrum of coping strategies used following the major terrorist attacks.

Employment Maintenance and Intimate Partner Violence.

PubMed

Borchers, Andrea; Lee, Rebecca C; Martsolf, Donna S; Maler, Jeff

2016-05-18

Intimate partner violence (IPV) is a major public health problem in the United States. Negative outcomes of IPV affect women's attainment and maintenance of employment. The purpose of this study was to develop a theoretical framework that described and explained the process by which women who have experienced IPV attain and maintain employment. Grounded theory methodology was used to analyze interviews of 34 women who had experienced IPV. Analysis suggested that women who had experienced IPV could attain employment; however, they had difficulty maintaining employment. Entanglement of work and IPV was experienced by all 34 participants because of the perpetrator controlling their appearance, sabotaging their work, interfering with their work, or controlling their finances. Some women described ways in which they disentangled work from IPV through a dynamic unraveling process, with periods of re-entanglement, resulting in job security and satisfaction. © 2016 The Author(s).

When Losing Means Winning: The Impact of Conflict in a Digital Game on Young Adults' Intentions to Get Protected from Cancer.

PubMed

Khalil, Georges E

2012-08-01

Despite the improved survival rate for patients with cancer in the United States, there is a need for successful intervention programs that can raise awareness about cancer risks among healthy young adults. This research experimentally examines how conflict in a digital game called "Re-Mission™" (HopeLab, Redwood City, CA) may influence young adults' perception of cancer risk, their motivation to get protected from cancer, and their intention to seek cancer-related information from their doctors. "Re-Mission" is a game in which players control a nanorobot that goes inside patients' virtual bodies to fight cancer cells. Two days after completing a baseline survey, participants (n=48) played "Re-Mission" at either low or high conflict (i.e., low or high level of obstacles and challenges in the game). Then, participants completed a post-experience survey. Participants in the high conflict condition experienced an increase in perceived susceptibility to and severity of cancer. They also increased their intentions to seek information by talking with a physician. Conflict also blocked any decrease in protective motivation. This study suggests that by virtually experiencing the consequences of cancer cell behavior, young adult players of "Re-Mission" increased in perception of cancer risks, protective motivation, and intentions to seek cancer-related information. In practice, health interventions should not only disseminate visual information about cancer, but also give the public the opportunity to virtually experience the consequences of cancer in order to understand the risks and become motivated to get protected. Implications for future research are also discussed.

Childhood Victimization and Lifetime Revictimization

ERIC Educational Resources Information Center

Widom, Cathy Spatz; Czaja, Sally J.; Dutton, Mary Ann

2008-01-01

Objective: To examine the fundamental hypothesis that childhood victimization leads to increased vulnerability for subsequent (re)victimization in adolescence and adulthood and, if so, whether there are differences in rates of experiencing traumas and victimizations by gender, race/ethnicity, and type of childhood abuse and/or neglect. Methods:…

Exploring Relationships between Personal Variables, Programmatic Variables, and Self-Efficacy in School-Based Agricultural Education

ERIC Educational Resources Information Center

McKim, Aaron J.; Velez, Jonathan J.; Clement, Haley Q.

2017-01-01

The educational importance of teacher self-efficacy necessitates research into variables presumed to significantly influence teacher self-efficacy. In the current study, the role of personal and programmatic variables on the self-efficacy of school-based agriculture teachers was explored. Self-efficacy was measured in five aspects of the…

A Cost Benefit Analysis of Professional Accreditation by ABET for Baccalaureate Engineering Degree Programs

ERIC Educational Resources Information Center

Yuen, Faye Sui Yee

2012-01-01

Tightening fiscal budgets and the growing emphasis on accountability has created a need to assess the value that programmatic accreditation provides. For degrees in engineering, ABET is the only organization recognized in the U.S. responsible for the programmatic accreditation. This research examines the costs and benefits of ABET accreditation to…

78 FR 53754 - Loup River Public Power District; Notice of Proposed Restricted Service List for a Programmatic...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-30

... List for a Programmatic Agreement for Managing Properties Included in or Eligible for Inclusion in the... for inclusion in, the National Register of Historic Places that could be affected by issuance of a new... person on the official service list for the above-captioned proceeding may request inclusion on the...

77 FR 27769 - PacifiCorp Energy; Notice of Proposed Restricted Service List for a Programmatic Agreement for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... in or Eligible for Inclusion in the National Register of Historic Places Rule 2010 of the Federal... programmatic agreement for managing properties included in, or eligible for inclusion in, the National Register... proceeding may request inclusion on the restricted service list, or may request that a restricted service...

Summary document of tasks performed on the Shuttle-C/NLS contract

NASA Technical Reports Server (NTRS)

1993-01-01

During FY92, USBI performed many programmatic related tasks. These programmatic tasks have been categorized as follows: (1) acquisition; (2) project engineering/program planning; and (3) cost. The reports associated with these tasks follow in paragraphs 1.1.1 through 1.3.3. Proceeding each task report is a brief description of the contents contained within.

42 CFR 137.71 - May the Secretary and the Self-Governance Tribe develop separate programmatic reporting...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false May the Secretary and the Self-Governance Tribe..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Statutorily Mandated Grants § 137.71 May the Secretary and the Self-Governance Tribe develop separate programmatic reporting requirements for statutorily...

76 FR 66281 - Withdrawal of the Notice of Intent To Prepare a Programmatic Environmental Impact Statement for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

... DEPARTMENT OF DEFENSE Department of the Army Withdrawal of the Notice of Intent To Prepare a Programmatic Environmental Impact Statement for the Stationing and Operation of Joint High Speed Vessels AGENCY... Environmental Impact Statement (PEIS) for the stationing and operation of up to 12 Joint High Speed Vessels...

75 FR 10814 - Proposed Programmatic Safe Harbor Agreement for the Sacramento River Conservation Area Forum in...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

...] Proposed Programmatic Safe Harbor Agreement for the Sacramento River Conservation Area Forum in Shasta... Enhancement of Survival Permit from the Sacramento River Conservation Area Forum (applicant) under the... Conservation Area Forum under the Act (16 U.S.C 1531 et seq.). The permit application includes a proposed Safe...

Continuation of Programmatic Research on Curricular Modules for Early Childhood Education and Parent Participation. Final Report.

ERIC Educational Resources Information Center

Adkins, Dorothy C.; O'Malley, J. Michael

Four projects, conducted as part of an ongoing programmatic research effort to develop and evaluate curricular modules for Head Start classes, are presented. Project A was an attempt to identify the effectiveness of an intervention approach that involved the introduction into two classes of curricula in language, mathematics, motivation, and…

Design of the Recovery Trajectory for JAXA Venus Orbiter Akatsuki

NASA Astrophysics Data System (ADS)

Campagnola, Stefano; Kawakatsu, Yasuhiro

2015-12-01

Akatsuki ("dawn" in Japanese) is the JAXA Venus orbiter that was scheduled to enter orbit around Venus on Dec. 7 th , 2010. Following the failure of the main engine during the orbit insertion maneuver, the spacecraft escaped Venus on a 200-day orbit around the Sun, only to return in early 2017. This paper presents the design and implementation of the recovery trajectory, which involves perihelion maneuvers to re-encounter Venus in late 2015. Relying only on the onboard propellant, the trajectory rescued the mission by (1) anticipating the beginning of the science phase within the nominal lifetime of the spacecraft, and (2) halving the Δ v requirements for the orbit insertion maneuver. Several trajectories are designed with an innovative use of a technique called non-tangent V-Infinity Leveraging Transfers (VILTs). Candidate solutions are then recomputed in higher fidelity models, and one solution is finally selected for its low Δv requirements and for programmatic reasons. The results of the perihelion maneuver campaign are also presented.

Predicting the mental health of college students with psychological capital.

PubMed

Selvaraj, Priscilla Rose; Bhat, Christine Suniti

2018-06-01

Behavioral health treatment is grounded in the medical model with language of deficits and problems, rather than resources and strengths. With developments in the field of positive psychology, re-focusing on well-being rather than illness is possible. The primary purpose of this study was to examine relationships and predictions that exist between levels of mental health in college students, i.e., flourishing, moderate mental health, and languishing, and psychological capital (PsyCap). For this cross-sectional, exploratory study survey method was used for data collection and for analyses of results a series of descriptive, correlation, ANOVA, and multiple regression analyses were done. Results indicated that developing positive psychological strengths such as hope, efficacy, resilience, and optimism (acronym HERO) within college students significantly increased their positive mental health. Based on the predictive nature of PsyCap, mental health professionals may engage more in creating programs incorporating PsyCap development intervention for college students. Implications for counseling and programmatic services for college students are presented along with suggestions for future research.

Incidence and risk factors for epidural re-siting in parturients with breakthrough pain during labour epidural analgesia: a cohort study.

PubMed

Sng, B L; Tan, M; Yeoh, C J; Han, N-L R; Sultana, R; Assam, P N; Sia, A T

2018-05-01

Epidural re-siting is one of the significant events during labour epidural analgesia that may result in decreased patient satisfaction. The aim of our study was to investigate the incidence of and factors associated with epidural re-siting in parturients using epidural analgesia, with an emphasis on those with breakthrough pain. A retrospective cohort study of 10170 parturients who received labour epidural analgesia. The primary outcome was the incidence of epidural re-siting (binary data). Univariate and multivariate logistic regression analysis were performed to find associated risk factors for re-siting. Less than 1% (0.85%, 86/10170) of the women in the study had their epidural re-sited. Amongst the subset of women with breakthrough pain, the incidence of epidural re-siting was higher (4.7%, 68/1454). Most of the women who had their epidural re-sited had experienced breakthrough pain (79%, 68/86). Amongst all parturients, the presence of breakthrough pain (OR=21.31), hypotension (OR=4.18) and venous puncture (OR=2.74) were significantly associated with re-siting. Amongst the parturients with breakthrough pain who required epidural re-siting, lower cervical dilatation (OR=0.81), higher number of episodes of breakthrough pain (OR=1.83) and patchy block (OR=4.37) were significantly associated with re-siting. The areas-under-curves of two multivariate models were 0.894 and 0.806 respectively. In our institution, the incidence of epidural catheter re-siting was low in all patients. However, the majority of patients whose catheters were re-sited had exhibited breakthrough pain. The risk factors associated with the need for re-siting of catheters in all patients differed from those who had breakthrough pain. Copyright © 2017 Elsevier Ltd. All rights reserved.

Community-based treatment of advanced HIV disease: introducing DOT-HAART (directly observed therapy with highly active antiretroviral therapy).

PubMed Central

Farmer, P.; Léandre, F.; Mukherjee, J.; Gupta, R.; Tarter, L.; Kim, J. Y.

2001-01-01

In 2000, acquired immunodeficiency syndrome (AIDS) overtook tuberculosis (TB) as the world's leading infectious cause of adult deaths. In affluent countries, however, AIDS mortality has dropped sharply, largely because of the use of highly active antiretroviral therapy (HAART). Antiretroviral agents are not yet considered essential medications by international public health experts and are not widely used in the poor countries where human immunodeficiency virus (HIV) takes its greatest toll. Arguments against the use of HAART have mainly been based on the high cost of medications and the lack of the infrastructure necessary for using them wisely. We re- examine these arguments in the setting of rising AIDS mortality in developing countries and falling drug prices, and describe a small community-based treatment programme based on lessons gained in TB control. With the collaboration of Haitian community health workers experienced in the delivery of home-based and directly observed treatment for TB, an AIDS-prevention project was expanded to deliver HAART to a subset of HIV patients deemed most likely to benefit. The inclusion criteria and preliminary results are presented. We conclude that directly observed therapy (DOT) with HAART, "DOT-HAART", can be delivered effectively in poor settings if there is an uninterrupted supply of high-quality drugs. PMID:11799447

Water in orthopyroxene from abyssal spinel peridotites of the East Pacific Rise (ODP Leg 147: Hess Deep)

NASA Astrophysics Data System (ADS)

Hesse, Kirsten T.; Gose, Jürgen; Stalder, Roland; Schmädicke, Esther

2015-09-01

Abyssal spinel peridotites from Hess Deep, East Pacific Rise (ODP Leg 147) were investigated concerning their major, minor, and trace element mineral chemistry and the incorporation of structural water in orthopyroxene. The rocks are partially serpentinized harzburgites containing primary minerals of olivine, orthopyroxene, clinopyroxene, and spinel. Orthopyroxene is enstatitic with Mg# (Mg/(Mg + Fe)) between 0.90 and 0.92 and Al2O3 from 0.5 to 2.9 wt.%. The residual harzburgite experienced high degrees of melt removal in the spinel peridotite stability field. The average degree of partial melting was calculated to be 17.5% (range: 16.4-17.8%). Trace element data of ortho- and clinopyroxenes reflect this strong depletion, characteristic for the restitic nature of abyssal peridotites. Mantle re-equilibration temperatures around 1000 °C indicate that, after melt extraction and before exhumation to the ocean floor, the rocks experienced significant cooling in the spinel peridotite facies. Water contents of orthopyroxene range from 86 to 233 wt. ppm H2O with an average concentration of 142 wt. ppm H2O. These results represent the first data on water contents in the sub-pacific mantle obtained by direct measurements of sub-oceanic peridotite. The water contents are not related to mineral chemistry, stratigraphy, melting degree, mantle equilibrium conditions or oxidation state. Calculated post-melt peridotite water contents vary between 40 and 100 wt. ppm H2O. Compared to Mid-Atlantic Ridge peridotites, the East Pacific Rise samples of Leg 147 contain somewhat lower water concentrations than samples from Leg 153 and considerably higher contents than those of Leg 209 (Gose et al., 2009; Schmädicke et al., 2011). In Leg 147, the strongest OH absorbtion band occurs at 3420 cm- 1, wheras orthopyroxene from MAR peridotite (Legs 153 and 209) has its strongest absorbtion band at 3566 and 3522 cm- 1. The mantle equilibrium temperature of Leg 147 peridotites is lower than that of Leg 209 ( 1250 °C) but close to that of Leg 153 samples (950-1000 °C). The high degree of partial melting of Leg 147 peridotite samples overlaps with the Leg 209 samples. In accordance to this data we conclude that in order to obtain relatively high water contents of up to 233 wt. ppm in depleted peridotite, after melt removal water must have re-entered the orthopyroxene structure. We suggest that re-equilibration of water contents took place under spinel-facies conditions before exhumation of the tectonite, since elevated temperatures enhance diffusion and elevated pressures facilitate hydrogen uptake. The extended time span between melt removal and uplift inferred from significant isobaric cooling of at least 200 K at spinel-facies depth facilitates re-equilibration of water contents and may explain the high concentrations. Exhumation from spinel-facies depth was fast and accompanied by further cooling such that re-equilibration to lower pressure assemblages and decompression-induced water loss were prevented.

Threshold Levels of Infant and Under-Five Mortality for Crossover between Life Expectancies at Ages Zero, One and Five in India: A Decomposition Analysis.

PubMed

Dubey, Manisha; Ram, Usha; Ram, Faujdar

2015-01-01

Under the prevailing conditions of imbalanced life table and historic gender discrimination in India, our study examines crossover between life expectancies at ages zero, one and five years for India and quantifies the relative share of infant and under-five mortality towards this crossover. We estimate threshold levels of infant and under-five mortality required for crossover using age specific death rates during 1981-2009 for 16 Indian states by sex (comprising of India's 90% population in 2011). Kitagawa decomposition equations were used to analyse relative share of infant and under-five mortality towards crossover. India experienced crossover between life expectancies at ages zero and five in 2004 for menand in 2009 for women; eleven and nine Indian states have experienced this crossover for men and women, respectively. Men usually experienced crossover four years earlier than the women. Improvements in mortality below ages five have mostly contributed towards this crossover. Life expectancy at age one exceeds that at age zero for both men and women in India except for Kerala (the only state to experience this crossover in 2000 for men and 1999 for women). For India, using life expectancy at age zero and under-five mortality rate together may be more meaningful to measure overall health of its people until the crossover. Delayed crossover for women, despite higher life expectancy at birth than for men reiterates that Indian women are still disadvantaged and hence use of life expectancies at ages zero, one and five become important for India. Greater programmatic efforts to control leading causes of death during the first month and 1-59 months in high child mortality areas can help India to attain this crossover early.

Shifting the Abject: Examining Abjected Adolescence in Teacher Thinking

ERIC Educational Resources Information Center

Sarigianides, Sophia Tatiana

2016-01-01

Teachers' efforts to re-consider adolescence as a historically-situated social category exposes how dominant biological and psychological discourses of adolescence position youth who do not fit "proper" expectations of adolescence as abject. In this seven-month study with experienced White and Black teachers working with poor youth of…

Leading Technology-Rich Schools. Technology & Education, Connections (TEC)

ERIC Educational Resources Information Center

Levin, Barbara B.; Schrum, Lynne

2012-01-01

This timely book shows how award-winning secondary schools and districts are successfully using technology and making systemic changes to increase student engagement, improve achievement, and re-invigorate the teaching and learning process. Through in-depth case studies, we see how experienced school and district leaders use technology in…

Too Scared To Learn: Women, Violence, and Education.

ERIC Educational Resources Information Center

Horsman, Jenny

Based on research with literacy learners, instructors, and practicing therapists, this book re-examines learning through a lens focused on the prevalence of and effects of violence in women's lives. Section 1, "Canaries in the Mine," highlights a shift away from seeing those who have experienced violence as damaged and towards…

Re/imagining Higher Education Pedagogies: Gender, Emotion and Difference

ERIC Educational Resources Information Center

Burke, Penny Jane

2015-01-01

This article explores work published in "Teaching in Higher Education" that critically engages complex questions of difference and emotion in higher education pedagogies. It considers the ways that difference is connected to gender and misrecognition, and is experienced at the level of emotion, often through symbolic forms of violence…

Re/Learning Student Teaching Supervision: A Co/Autoethnographic Self-Study

ERIC Educational Resources Information Center

Butler, Brandon M.; Diacopoulos, Mark M.

2016-01-01

This article documents the critical friendship of an experienced teacher educator and a doctoral student through our joint exploration of student teaching supervision. By adopting a co/autoethnographic approach, we learned from biographical and contemporaneous critical incidents that informed short- and long-term practices. In particular, we…

Beyond Strength: Participant Perspectives on the Benefits of an Older Adult Exercise Program

ERIC Educational Resources Information Center

Kohn, Marlana; Belza, Basia; Petrescu-Prahova, Miruna; Miyawaki, Christina E.

2016-01-01

This study examines the expected and experienced benefits among participants in Enhance®Fitness (EF), an evidence-based group physical activity program for older adults. We also describe the implications for program dissemination (reach, implementation, and maintenance) within the RE-AIM (reach, effectiveness, adoption, implementation, and…

A Preschool Adventure: We're Going to Africa.

ERIC Educational Resources Information Center

Bartel, Virginia; Hart, Jane

2000-01-01

Discusses an interdisciplinary unit on Africa that was used with four-year-old students, mostly African Americans. Students studied African plains animals, built African round and square houses, experienced African music and stories, made African costumes, and took an imaginary trip to Africa. Includes an annotated bibliography. (CMK)

The Scope of Global Health Training in U.S. Obstetrics and Gynecology Residency Programs

PubMed Central

Hung, Kristin J.; Tsai, Alexander C.; Johnson, Timothy R.B.; MD, MPH, Rochelle P.; Bangsberg, David R.; Kerry, Vanessa B.

2013-01-01

Objective To enumerate global health training activities in U.S. obstetrics and gynecology residency programs, and to examine the worldwide distribution of programmatic activity relative to the maternal and perinatal disease burden. Methods Using a systematic, Web-based protocol, we searched for global health training opportunities at all U.S. obstetrics and gynecology residency programs. Country-level data on disability-adjusted life years due to maternal and perinatal conditions were obtained from the Global Burden of Disease study. We calculated Spearman’s rank correlation coefficients to estimate the cross-country association between programmatic activity and disease burden. Results Of the 243 accredited U.S. obstetrics and gynecology residency programs, we identified 41 (17%) with one of several possible predefined categories of programmatic activity. Thirty-three residency programs offered their residents opportunities to participate in one or more elective-based rotations, eight offered extended field-based training, and 18 offered research activities. A total of 128 programmatic activities were dispersed across 64 different countries. At the country level, the number of programmatic activities had a statistically significant association with the total disease burden due to maternal (Spearman’s ρ=0.37; 95% confidence interval [CI], 0.14-0.57) and perinatal conditions (ρ=0.34; 95% CI, 0.10-0.54) but not gynecologic cancers (ρ=−0.24; 95% CI, −0.46 to 0.01). Conclusions There are few global health training opportunities for U.S. obstetrics and gynecology residents. These activities are disproportionately distributed among countries with greater burdens of disease. PMID:24104785

Interpretation of Mössbauer experiment in a rotating system: A new proof for general relativity

NASA Astrophysics Data System (ADS)

Corda, Christian

2015-04-01

A historical experiment by Kündig on the transverse Doppler shift in a rotating system measured with the Mössbauer effect (Mössbauer rotor experiment) has been recently first re-analyzed and then replied by an experimental research group. The results of re-analyzing the experiment have shown that a correct re-processing of Kündig's experimental data gives an interesting deviation of a relative redshift between emission and absorption resonant lines from the standard prediction based on the relativistic dilatation of time. That prediction gives a redshift ∇E/E ≃ -1/2 v2/c2 where v is the tangential velocity of the absorber of resonant radiation, c is the velocity of light in vacuum and the result is given to the accuracy of first-order in v2/c2. Data re-processing gave ∇E/E ≃ - kv2/c2 with k = 0.596 ± 0.006. Subsequent new experimental results by the reply of Kündig experiment have shown a redshift with k = 0.68 ± 0.03 instead. By using Einstein Equivalence Principle, which states the equivalence between the gravitational "force" and the pseudo-force experienced by an observer in a non-inertial frame of reference (included a rotating frame of reference) here we re-analyze the theoretical framework of Mössbauer rotor experiments directly in the rotating frame of reference by using a general relativistic treatment. It will be shown that previous analyses missed an important effect of clock synchronization and that the correct general relativistic prevision in the rotating frame gives k ≃ 2/3 in perfect agreement with the new experimental results. Such an effect of clock synchronization has been missed in various papers in the literature with some subsequent claim of invalidity of relativity theory and/or some attempts to explain the experimental results through "exotic" effects. Our general relativistic interpretation shows, instead, that the new experimental results of the Mössbauer rotor experiment are a new, strong and independent, proof of Einstein general relativity. In the final section of the paper we discuss an analogy with the use of General Relativity in Global Positioning Systems.

Thermoregulation and the determinants of heat transfer in Colias butterflies.

PubMed

Kingsolver, Joel G; Moffat, Robert J

1982-04-01

As a means of exploring behavioral and morphological adaptations for thermoregulation in Colias butterflies, convective heat transfer coefficients of real and model butterflies were measured in a wind tunnel as a function of wind speed and body orientation (yaw angle). Results are reported in terms of a dimensionless heat transfer coefficient (Nusselt number, Nu) and a dimensionless wind speed (Reynolds number, Re), for a wind speed range typical of that experienced by basking Colias in the field. The resultant Nusselt-Reynolds (Nu-Re) plots thus indicate the rates of heat transfer by forced convection as a function of wind speed for particular model geometries.For Reynolds numbers throughout the measured range, Nusselt numbers for C. eurytheme butterflies are consistently lower than those for long cylinders, and are independent of yaw angle. There is significant variation among individual butterflies in heat transfer coefficients throughout the Re range. Model butterflies without artificial fur have Nu-Re relations similar to those for cylinders. Heat transfer in these models depends upon yaw angle, with higher heat transfer at intermediate yaw angles (30-60°); these yaw effects increase with increasing Reynolds number. Models with artificial fur, like real Colias, have Nusselt numbers which are consistently lower than those for models without fur at given Reynolds numbers throughout the Re range. Unlike real Colias, however, the models with fur do show yaw angle effects similar to those for models without fur.The independence of heat loss from yaw angle for real Colias is consistent with field observations indicating no behavioral orientation to wind direction. The presence of fur on the models reduces heat loss but does not affect yaw dependence. The large individual variation in heat transfer coefficients among butterflies is probably due to differences in fur characteristics rather than to differences in wing morphology.Finally, a physical model of a butterfly was constructed which accurately simulates the body temperatures of basking Colias in the field for a variety of radiation and wind velocity conditions. The success of the butterfly simulator in mimicking Colias thermal characteristics confirms our preliminary understanding of the physical bases for and heat transfer mechanisms underlying thermoregulatory adaptations in these butterflies.

Re-accumulation Scenarios Governing Final Global Shapes of Rubble-Pile Asteroids

NASA Astrophysics Data System (ADS)

Hestroffer, Daniel; Tanga, P.; Comito, C.; Paolicchi, P.; Walsh, K.; Richardson, D. C.; Cellino, A.

2009-05-01

Asteroids, since the formation of the solar system, are known to have experienced catastrophic collisions, which---depending on the impact energy---can produce a major disruption of the parent body and possibly give birth to asteroid families or binaries [1]. We present a general study of the final shape and dynamical state of asteroids produced by the re-accumulation process following a catastrophic disruption. Starting from a cloud of massive particles (mono-disperse spheres) with given density and velocity distributions, we analyse the final shape, spin state, and angular momentum of the system from numerical integration of a N-body gravitational system (code pkdgrav [2]). The re-accumulation process itself is relatively fast, with a dynamical time corresponding to the spin-period of the final body (several hours). The final global shapes---which are described as tri-axial ellipsoids---exhibit slopes consistent with a degree of shear stress sustained by interlocking particles. We point out a few results: -the final shapes are close to those of hydrostatic equilibrium for incompressible fluids, preferably Maclaurin spheroid rather than Jacobi ellipsoids -for bodies closest to the sequence of hydrostatic equilibrium, there is a direct relation between spin, density and outer shape, suggesting that the outer surface is nearly equipotential -the evolution of the shape during the process follows a track along a gradient of potential energy, without necessarily reaching its minimum -the loose random packing of the particles implies low friction angle and hence fluid-like behaviour, which extends the results of [3]. Future steps of our analysis will include feature refinements of the model initial conditions and re-accumulation process, including impact shakings, realistic velocity distributions, and non equal-sized elementary spheres. References [1] Michel P. et al. 2001. Science 294, 1696 [2] Leinhardt Z.M. et al. 2000. Icarus 146, 133 [3] Richardson D.C. et al. 2005. Icarus 173, 349

Alternatives to Re-Planning: Methods for Plan Re-Evaluation at Runtime

NASA Technical Reports Server (NTRS)

Benazera, Emmanuel

2005-01-01

Current planning algorithms have difficulty handling the complexity that is due to an increase in domain uncertainty, and especially in the case of multi-dimensional continuous spaces. Therefore, they produce plans that do not take into account numerous situations that can occur at runtime, such as faults or other changes in the planning domain itself. Thus there is a gap between the plan generation and the reality experienced at runtime. Here we present two methods that allow the plan conditionals to be revised w.r.t. uncertainty on the system as estimated at runtime.

Satellite Power Systems (SPS) concept definition study (Exhibit D). Volume 6, part 1: Cost and Programmatics

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1981-01-01

A summary of the cost data reviewed as well as conclusions and recommendations are presented. Cost and programmatic aspects of Rockwell's SPS CR-2 reference configuration were based on the results of several contracts with NASA and independent company-sponsored activities by the Space Operations and Satellite Systems Division of Rockwell International.

Modular space station phase B extension period executive summary

NASA Technical Reports Server (NTRS)

Tischler, A. A.; Could, C. L.

1972-01-01

A narrative summary is presented of technical, programmatic, and planning information developed during the space station definition study extension period. The modular space station is emphasized, but tasks pertaining to shuttle sorties missions and information management advanced development are included. A series of program options considering technical, schedule, and programmatic alternatives to the baseline program are defined and evaluated.

77 FR 50481 - Development of Programmatic Requirements for the State and Local Implementation Grant Program To...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-21

... the Middle Class Tax Relief and Job Creation Act of 2012 (Act). The Notice describes the programmatic... Tax Relief and Job Creation Act of 2012 (Act).\\1\\ The Act meets a long-standing priority of the Obama... will help them to do their jobs more safely and effectively. \\1\\ Middle Class Tax Relief and Job...

76 FR 57751 - Notice of Availability of a Draft Programmatic Environmental Impact Statement for Northern Border...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... particular place. Because this effort is programmatic in nature, the Draft PEIS does not define effects for a... the purposes of the PEIS, the Northern Border is defined as the area between the United States and... environmental quality and the government's role in protecting it. The essence of NEPA is the requirement that...

An Analysis of Programmatic Variables Relating to the Pass Rates on the Licensure Examination by Practical Nurses in Tennessee Technology Centers

ERIC Educational Resources Information Center

Simpson, Janis Lee

2013-01-01

The purpose of this quantitative research study was to determine the degree to which Licensed Practical Nursing programmatic variables positively correlate with select Tennessee Technology Center institution pass rates on the licensure examination--NCLEX-PNRTM. This study investigated the relationship between the dependent variable of NCLEX-PNRTM…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kolbasin, V. A.; Ivanov, A. I.; Pedash, V. Y.

The two pulse shape discrimination methods were implemented in real-time. The pulse gradient analysis method was implemented programmatically on PC. The method based on artificial neural network was programmatically implemented using CUDA platform. It is shown that both implementations can provide up to 10{sup 6} pulses per second processing performance. The results for pulse shape discrimination using polycrystalline stilbene and LiF detectors were shown. (authors)

Information engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunt, D.N.

1997-02-01

The Information Engineering thrust area develops information technology to support the programmatic needs of Lawrence Livermore National Laboratory`s Engineering Directorate. Progress in five programmatic areas are described in separate reports contained herein. These are entitled Three-dimensional Object Creation, Manipulation, and Transport, Zephyr:A Secure Internet-Based Process to Streamline Engineering Procurements, Subcarrier Multiplexing: Optical Network Demonstrations, Parallel Optical Interconnect Technology Demonstration, and Intelligent Automation Architecture.

76 FR 21003 - Notice of Intent To Prepare a Programmatic Environmental Impact Statement (EIS) and Possible Land...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

... Allocation of Oil Shale and Tar Sands Resources on Lands Administered by the Bureau of Land Management in... to prepare a Programmatic EIS for Allocation of Oil Shale and Tar Sands Resources on Lands... following methods: Web site: http://blm.gov/st5c . Mail: BLM Oil Shale and Tar Sands Resources Leasing...

Northwestern University Programmatic College of Commerce and Industry: One of a Series of Guides for Planning and Operating a Corporate/College Project.

ERIC Educational Resources Information Center

Council on Corporate/College Communications, Washington, DC.

The Programmatic College of Commerce and Industry at Northwestern University is described as an innovative approach to the study of business as an institution. The program consists of weekly, noncredit, dinner-lecture-discussion meetings attended by students, faculty, and business people. Discussions center on problems facing business, on the…

Identifying components for programmatic latent tuberculosis infection control in the European Union

PubMed Central

Sandgren, Andreas; Vonk Noordegraaf-Schouten, Jannigje M; Oordt-Speets, Anouk M; van Kessel, Gerarda B; de Vlas, Sake J; van der Werf, Marieke J

2016-01-01

Individuals with latent tuberculosis infection (LTBI) are the reservoir of Mycobacterium tuberculosis in a population and as long as this reservoir exists, elimination of tuberculosis (TB) will not be feasible. In 2013, the European Centre for Disease Prevention and Control (ECDC) started an assessment of benefits and risks of introducing programmatic LTBI control, with the aim of providing guidance on how to incorporate LTBI control into national TB strategies in European Union/European Economic Area (EU/EEA) Member States and candidate countries. In a first step, experts from the Member States, candidate countries, and international and national organisations were consulted on the components of programmatic LTBI control that should be considered and evaluated in literature reviews, mathematical models and cost-effectiveness studies. This was done through a questionnaire and two interactive discussion rounds. The main components identified were identification and targeting of risk groups, determinants of LTBI and progression to active TB, optimal diagnostic tests for LTBI, effective preventive treatment regimens, and to explore the potential for combining LTBI control with other health programmes. Political commitment, a solid healthcare infrastructure, and favourable economic situation in specific countries were identified as essential to facilitate the implementation of programmatic LTBI control. PMID:27589214

Variations in Criterion A and PTSD Rates in a Community Sample of Women

PubMed Central

Anders, Samantha; Frazier, Patricia; Frankfurt, Sheila

2010-01-01

We assessed PTSD prevalence and symptoms as a function of whether participants’ worst lifetime event met Criterion A1 for PTSD (DSM-IV-TR; APA, 2000) and whether the event was directly or indirectly experienced in a community sample of adult women (N = 884). Exposure to both non-Criterion A1 and Criterion A1 events was systematically assessed. PTSD was assessed with regard to participants’ self-nominated worst event using the PTSD module of the SCID-I/NP (First, Spitzer, Gibbon, & Williams, 1997). There were no differences in PTSD prevalence rates between Criterion A1 and non-A1 events; however, directly-experienced worst events were significantly more likely to meet PTSD criteria than were indirectly-experienced worst events. Non-Criterion A1 and directly-experienced worst events were associated with significantly more PTSD symptoms than were Criterion A1 or indirectly-experienced events, respectively. Criterion A2 (experiencing fear, helplessness, or horror) had little effect on PTSD rates. PMID:20888184

The effects of a reminder of underwater trauma on behaviour and memory-related mechanisms in the rat dentate gyrus.

PubMed

Ardi, Ziv; Ritov, Gilad; Lucas, Morgan; Richter-Levin, Gal

2014-04-01

Intrusive re-experiencing is a core symptom in post-traumatic stress disorder (PTSD), often triggered by contextual cues associated with the trauma. It is not yet clear if intrusive re-experiencing is only the result, or whether it may contribute to the establishment of PTSD following acute stress. This study aimed at examining the impact of an underwater trauma (UWT) reminder on anxiety-like behaviour and on neuronal activity and plasticity in the hippocampus and the amygdala. Sprague-Dawley rats were exposed to UWT and 24 h later were re-exposed to the context. The effects on behaviour, activation of the amygdala (BLA) and dentate gyrus (DG), and on long-term potentiation (LTP) and local circuit activity (frequency-dependent inhibition (FDI) and paired-pulse inhibition (PPI)) in the DG were assessed. The exposure to UWT by itself resulted in increased anxiety behaviour in the open field, together with increased PPI. Upon exposure to the UWT reminder, an additional increase in anxiety was also observed in the EPM and in FDI. Moreover, reminder exposure resulted in impaired DG LTP and a significant BLA extracellular-signal-regulated kinases (ERK) 2 activation. In conclusion, these observed effects of exposure to a trauma reminder, following the exposure to the initial trauma, might be associated with the progression of trauma-related pathologies and the development of related disorders.

Satellite Power Systems (SPS) concept definition study, exhibit C. Volume 2, part 2: System engineering, cost and programmatics

NASA Technical Reports Server (NTRS)

Hanley, G. M.

1979-01-01

Volume 2, Part 2, of a seven volume Satellite Power Systems (SPS) report is presented. Part 2 covers cost and programmatics and is divided into four sections. The first section gives illustrations of the SPS reference satellite and rectenna concept, and an overall scenario for SPS space transportation involvement. The second section presents SPS program plans for the implementation of PHASE C/D activities. These plans describe SPS program schedules and networks, critical items of systems evolution/technology development, and the natural resources analysis. The fourth section presents summary comments on the methods and rationale followed in arriving at the results documented. Suggestions are also provided in those areas where further analysis or evaluation will enhance SPS cost and programmatic definitions.

A Systematic Literature Review of the Childbearing Cycle as Experienced by Survivors of Sexual Abuse.

PubMed

LoGiudice, Jenna Alana

For women who have experienced sexual abuse, the physical changes associated with pregnancy and the lack of control during birth can be catalysts for trauma from past abuse to resurface. This systematic review offers women's health care providers a thorough evaluation of the state of the science on survivors' childbearing experiences. The literature shows that lack of control, dissociation, and flashbacks are common themes. Re-experiencing of the trauma occurred during various stages of childbirth and was traumatizing to women. Nurses and other clinicians providing care to childbearing women can provide control to survivors during health care encounters and can form therapeutic relationships to help them have more positive childbirth experiences. © 2016 AWHONN, the Association of Women’s Health, Obstetric and Neonatal Nurses.

Status and Plans for NSTX-U Recovery

NASA Astrophysics Data System (ADS)

Hawryluk, R. J.; Gerhardt, S.; Menard, J.; Neumeyer, C.

2017-10-01

The NSTX-U device experienced a series of technical problems; the most recent of which was the failure of one of the poloidal magnetic field coils, which has rendered the device inoperable and in need of significant repair. As a result of these incidents, the Laboratory performed a very comprehensive analysis of all of the systems on NSTX-U. Through an integrated system's analysis approach, this process identified which actions need to be taken to form a corrective action plan to ensure reliable and predictable operation. The actions required to address the deficiencies were reviewed by external experts who made recommendations on four high-level programmatic decisions regarding the inner poloidal field coils, limitations to the required bakeout temperature needed for conditioning of the vacuum vessel, divertor and wall protection tiles and coaxial helicity injection. The plans for addressing the recommendations from the external review panels will be presented. This research was sponsored by the U.S. Dept. of Energy under contract DE-AC02-09CH11466.

NOW AND THEN: The Global Nutrition Transition: The Pandemic of Obesity in Developing Countries

PubMed Central

Popkin, Barry M.; Adair, Linda S.; Ng, Shu Wen

2011-01-01

Decades ago discussion of an impending global pandemic of obesity was thought of as heresy. Diets in the 1970’s began to shift toward increased reliance upon processed foods, increased away from home intake and greater use of edible oils and sugar-sweetened beverages. Reduced physical activity and increased sedentary time was seen also. These changes began in the early 1990-‘s in the low and middle income world but did not become clearly recognized until diabetes, hypertension and obesity began to dominate the globe. Urban and rural areas from sub-Saharan Africa and South Asia’s poorest countries to the higher income ones are shown to have experienced rapid increases in overweight and obesity status. Concurrent rapid shifts in diet and activity are documented. An array of large-scale programmatic and policy shifts are being explored in a few countries; however despite the major health challenges faced, few countries are serious in addressing prevention of the dietary challenges faced. PMID:22221213

Is the Relationship between Common Mental Disorder and Adiposity Bidirectional? Prospective Analyses of a UK General Population-Based Study.

PubMed

Fezeu, Léopold K; Batty, G David; Batty, David G; Gale, Catharine R; Kivimaki, Mika; Hercberg, Serge; Czernichow, Sebastien

2015-01-01

The direction of the association between mental health and adiposity is poorly understood. Our objective was to empirically examine this link in a UK study. This is a prospective cohort study of 3 388 people (men) aged ≥ 18 years at study induction who participated in both the UK Health and Lifestyle Survey at baseline (HALS-1, 1984/1985) and the re-survey (HALS-2, 1991/1992). At both survey examinations, body mass index, waist circumference and self-reported common mental disorder (the 30-item General Health Questionnaire, GHQ) were measured. Logistic regression models were used to compute odds ratios (OR) and accompanying 95% confidence intervals (CI) for the associations between (1) baseline common mental disorder (QHQ score > 4) and subsequent general and abdominal obesity and (2) baseline general and abdominal obesity and re-survey common mental disorders. After controlling for a range of covariates, participants with common mental disorder at baseline experienced greater odds of subsequently becoming overweight (women, OR: 1.30, 1.03 - 1.64; men, 1.05, 0.81 - 1.38) and obese (women, 1.26, 0.82 - 1.94; men, OR: 2.10, 1.23 - 3.55) than those who were free of common mental disorder. Similarly, having baseline common mental health disorder was also related to a greater risk of developing moderate (1.57, 1.21 - 2.04) and severe (1.48, 1.09 - 2.01) abdominal obesity (women only). Baseline general or abdominal obesity was not associated with the risk of future common mental disorder. These findings of the present study suggest that the direction of association between common mental disorders and adiposity is from common mental disorder to increased future risk of adiposity as opposed to the converse.

Biomimetic light-harvesting funnels for re-directioning of diffuse light.

PubMed

Pieper, Alexander; Hohgardt, Manuel; Willich, Maximilian; Gacek, Daniel Alexander; Hafi, Nour; Pfennig, Dominik; Albrecht, Andreas; Walla, Peter Jomo

2018-02-14

Efficient sunlight harvesting and re-directioning onto small areas has great potential for more widespread use of precious high-performance photovoltaics but so far intrinsic solar concentrator loss mechanisms outweighed the benefits. Here we present an antenna concept allowing high light absorption without high reabsorption or escape-cone losses. An excess of randomly oriented pigments collects light from any direction and funnels the energy to individual acceptors all having identical orientations and emitting ~90% of photons into angles suitable for total internal reflection waveguiding to desired energy converters (funneling diffuse-light re-directioning, FunDiLight). This is achieved using distinct molecules that align efficiently within stretched polymers together with others staying randomly orientated. Emission quantum efficiencies can be >80% and single-foil reabsorption <0.5%. Efficient donor-pool energy funneling, dipole re-orientation, and ~1.5-2 nm nearest donor-acceptor transfer occurs within hundreds to ~20 ps. Single-molecule 3D-polarization experiments confirm nearly parallel emitters. Stacked pigment selection may allow coverage of the entire solar spectrum.

Prevalence of and factors influencing posttraumatic stress disorder among mothers of children under five in Kabul, Afghanistan, after decades of armed conflicts

PubMed Central

Seino, Kaoruko; Takano, Takehito; Mashal, Taufiq; Hemat, Shafiqullah; Nakamura, Keiko

2008-01-01

Background In the period following wars and other forms of armed conflict, health and quality of life of mothers is a major concern as they have the closest contact with children. The present study was performed to examine the impact of exposure to events related to armed conflicts on post traumatic stress disorder (PTSD) among women raising children, and to identify factors that alleviate the negative consequences of exposure to traumatic events. Methods A structured interview survey was conducted in Kabul Province, Afghanistan, in 2006. The subjects were the mothers of children less than 5 years old randomly selected from 1400 households in Kabul Province, Afghanistan. Symptoms of PTSD were assessed according to the criteria of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). Exposure to traumatic events related to armed conflict, experience of hardship with regard to basic needs, resources that the subjects seek for mental health support, and socioeconomic variables were evaluated. Logistic regression analysis was performed to determine the association between PTSD symptoms and predictor variables. Results The prevalence rate of PTSD among 1172 women participated in this study was 29.8%. The most prevalent symptom was arousal (74.8%), followed by re-experiencing (54.9%) and avoidance (33.7%). The prevalence rate of PTSD symptoms among subjects who reported having experienced at least one event related to armed conflict (52.7%) was significantly higher than that among those who reported no such experiences (9.6%). Experience of food shortage was independently associated with PTSD. Seeking support for mental health was related to lower prevalence of PTSD symptoms among those who reported no direct experience of events related to armed conflict. However, no such relationship was observed with PTSD symptoms among those who reported having direct experience of events related to armed conflict. Conclusion Direct exposure to traumatic events was significantly associated with PTSD symptoms among women raising children. For those who had experienced armed conflict-related events, food security mitigated the occurrence of PTSD symptoms; however, support seeking behavior did not show a significant mitigating influence on PTSD. Means to alleviate the negative influence of exposure to armed conflicts on the quality of life of women should be developed from the viewpoint of quality of mental health support and avoidance of material hardship. PMID:18433474

Recovery and nonrecovery of the untrained state in an exchange-coupled system

NASA Astrophysics Data System (ADS)

Jutimoosik, Jaru; Yimnirun, Rattikorn; Setzer, Annette; Esquinazi, Pablo; Stahn, Jochen; Paul, Amitesh

2015-06-01

We report depth sensitive investigations of the magnetic interaction between exchange-coupled stacked CoO and ferromagnetic Co bilayers (separated by thick Au layers) as we explore the degree of recovery of the untrained state after the first two field cycles. Such a recovery is expected by field cycling a reorientation field (HRE) along a direction (ΩRE) away from the initial field cooling direction. Measurements as a function of ΩRE and the strength of HRE (along each direction) map the influence of ΩRE on the reversal mechanism in the layers and thereby the degree of recovery. Our results are consistent with the earlier observations in similar systems that was realized with ΩRE=90∘ . We ascribe these partial and/or significant recoveries to the unchanged sense of rotation after initial field cooling of the ferromagnetic magnetization upon each field cycling. Furthermore, in our system, we find that this recovery can be regulated by choosing various other HRE and ΩRE values without changing the rotational sense. The best recipe for recovery is identified for ΩRE=45∘ , that can be achieved partially with HRE=3.0 kOe and remain significant even with HRE=10.0 kOe. In this study we not only understand the fundamental mechanism in the recovery of training, but also instigate its technological prospects by lifting the directional restrictions of the reorientation field.

Re/creating entrepreneurs of the self: discourses of worker and employee 'value' and current vocational rehabilitation practices.

PubMed

Fadyl, Joanna; McPherson, Kathryn; Nicholls, David

2015-05-01

Vocational rehabilitation for people experiencing work disability is a social practice often situated within health services, but the social and political drivers and effects of this practice are rarely critically analysed in health research or policy. In this study we used a Foucauldian theoretical perspective to analyse the ways in which current vocational rehabilitation practices in New Zealand re/produce notions of worker and employee 'value', and how different approaches to vocational rehabilitation deploy current discourses about value. We also consider the subject positions produced through these different approaches and the identities and actions they make possible for people experiencing work disability. The analysis showed that notions about the importance of worker and employee value in a job market are pervasive in vocational rehabilitation, and reflect wider societal discourses. However, the deployment of those discourses in different approaches to vocational rehabilitation practice are diverse, producing different opportunities and constraints for people experiencing disability. We argue that an examination of these various opportunities and constraints at the level of practice approaches is important, as considerable time and resources are allocated to developing solutions to help those who do not thrive in the current systems, yet we rarely critique the premises on which the systems are based. © 2015 The Authors. Sociology of Health & Illness © 2015 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

A qualitative evaluation of the 2005-2011 National Academic Centers of Excellence in Youth Violence Prevention Program.

PubMed

Holland, Kristin M; Vivolo-Kantor, Alana M; Dela Cruz, Jason; Massetti, Greta M; Mahendra, Reshma

2015-12-01

The Centers for Disease Control and Prevention's Division of Violence Prevention (DVP) funded eight National Academic Centers of Excellence (ACEs) in Youth Violence Prevention from 2005 to 2010 and two Urban Partnership Academic Centers of Excellence (UPACEs) in Youth Violence Prevention from 2006 to 2011. The ACEs and UPACEs constitute DVP's 2005-2011 ACE Program. ACE Program goals include partnering with communities to promote youth violence (YV) prevention and fostering connections between research and community practice. This article describes a qualitative evaluation of the 2005-2011 ACE Program using an innovative approach for collecting and analyzing data from multiple large research centers via a web-based Information System (ACE-IS). The ACE-IS was established as an efficient mechanism to collect and document ACE research and programmatic activities. Performance indicators for the ACE Program were established in an ACE Program logic model. Data on performance indicators were collected through the ACE-IS biannually. Data assessed Centers' ability to develop, implement, and evaluate YV prevention activities. Performance indicator data demonstrate substantial progress on Centers' research in YV risk and protective factors, community partnerships, and other accomplishments. Findings provide important lessons learned, illustrate progress made by the Centers, and point to new directions for YV prevention research and programmatic efforts. Published by Elsevier Ltd.

Moving forward by looking back: reflecting on a decade of CDC's work in sexual violence prevention, 2000-2010.

PubMed

DeGue, Sarah; Simon, Thomas R; Basile, Kathleen C; Yee, Sue Lin; Lang, Karen; Spivak, Howard

2012-12-01

In 2011, the Division of Violence Prevention (DVP) within CDC's Injury Center engaged an external panel of experts to review and evaluate its research and programmatic portfolio for sexual violence (SV) prevention from 2000 to 2010. This article summarizes findings from the review by highlighting DVP's key activities and accomplishments during this period and identifying remaining gaps in the field and future directions for SV prevention. DVP's SV prevention work in the 2000s included (1) raising the profile of SV as a public health problem, (2) shifting the field toward a focus on the primary prevention of SV perpetration, and (3) applying the public health model to SV research and programmatic activities. The panel recommended that DVP continue to draw attention to the importance of sexual violence prevention as a public health issue, build on prior investments in the Rape Prevention and Education Program, support high-quality surveillance and research activities, and enhance communication to improve the link between research and practice. Current DVP projects and priorities provide a foundation to actively address these recommendations. In addition, DVP continues to provide leadership and guidance to the research and practice fields, with the goal of achieving significant reductions in SV perpetration and allowing individuals to live to their full potential.

New tools and methods for direct programmatic access to the dbSNP relational database

PubMed Central

Saccone, Scott F.; Quan, Jiaxi; Mehta, Gaurang; Bolze, Raphael; Thomas, Prasanth; Deelman, Ewa; Tischfield, Jay A.; Rice, John P.

2011-01-01

Genome-wide association studies often incorporate information from public biological databases in order to provide a biological reference for interpreting the results. The dbSNP database is an extensive source of information on single nucleotide polymorphisms (SNPs) for many different organisms, including humans. We have developed free software that will download and install a local MySQL implementation of the dbSNP relational database for a specified organism. We have also designed a system for classifying dbSNP tables in terms of common tasks we wish to accomplish using the database. For each task we have designed a small set of custom tables that facilitate task-related queries and provide entity-relationship diagrams for each task composed from the relevant dbSNP tables. In order to expose these concepts and methods to a wider audience we have developed web tools for querying the database and browsing documentation on the tables and columns to clarify the relevant relational structure. All web tools and software are freely available to the public at http://cgsmd.isi.edu/dbsnpq. Resources such as these for programmatically querying biological databases are essential for viably integrating biological information into genetic association experiments on a genome-wide scale. PMID:21037260

Diabetes mellitus and tuberculosis: programmatic management issues

PubMed Central

Kumar, A. M. V.; Satyanarayana, S.; Lin, Y.; Zachariah, R.; Lönnroth, K.; Kapur, A.

2015-01-01

SUMMARY In August 2011, the World Health Organization and the International Union Against Tuberculosis and Lung Disease launched the Collaborative Framework for Care and Control of Tuberculosis (TB) and diabetes mellitus (DM) to guide policy makers and implementers in combatting the epidemics of both diseases. Progress has been made, and includes identifying how best to undertake bidirectional screening for both diseases, how to provide optimal treatment and care for patients with dual disease and the most suitable framework for monitoring and evaluation. Key programmatic challenges include the following: whether screening should be directed at all patients or targeted at those with high-risk characteristics; the most suitable technologies for diagnosing TB and diabetes in routine settings; the best time to screen TB patients for DM; how to provide an integrated, coordinated approach to case management; and finally, how to persuade non-communicable disease programmes to adopt a cohort analysis approach, preferably using electronic medical records, for monitoring and evaluation. The link between DM and TB and the implementation of the collaborative framework for care and control have the potential to stimulate and strengthen the scale-up of non-communicable disease care and prevention programmes, which may help in reducing not only the global burden of DM but also the global burden of TB. PMID:26162352

Diagenetic palaeotemperatures from aqueous fluid inclusions: re- equilibration of inclusions in carbonate cements by burial heating.

USGS Publications Warehouse

Burruss, R.C.

1987-01-01

Calculations based on the observed behaviour of inclusions in fluorite under external confining P allows prediction of the T and depths of burial necessary to initiate re-equilibration of aqueous inclusions in the common size range 40-4 mu m. Heating of 20-60oC over the initial trapping T may cause errors of 10-20oC in the homogenization T. This suggests that re-equilibration may cause aqueous inclusions in carbonates to yield a poor record of their low-T history, but a useful record of the maximum T experienced by the host rock. Previous work suggests that inclusions containing petroleum fluids will be less susceptible to re-equilibration.This and the following six abstracts represent papers presented at a joint meeting of the Applied Mineralogy Group of the Mineralogical Society and the Petroleum Group of the Geological Society held in Newcastle upon Tyne in April 1986.-R.A.H.

First-in-man experience with the ReVive PV peripheral thrombectomy device for the revascularization of below-the-knee embolic occlusions.

PubMed

Landau, David; Moomey, Charles; Fiorella, David

2014-10-01

To report the initial use of a novel thrombectomy device for revascularization of below-the-knee thromboembolic occlusions encountered during proximal revascularization procedures. The ReVive PV Peripheral Thrombectomy Device is a non-detachable, self-expanding stent-like device recently approved for peripheral thrombectomy. Four patients (3 women; mean age 68.8 years) undergoing proximal revascularization procedures experienced embolic occlusions of all 3 trifurcation vessels in 1 patient, the tibioperoneal trunk alone in 2 cases, and the peroneal artery alone in the last patient. In all cases, the involved arteries represented the primary or sole vessel(s) providing outflow to the lower extremity. In each case, the ReVive PV device was used to successfully extract the thrombus and restore flow to the distal extremity. No complications were encountered during any of the procedures. The ReVive PV peripheral thrombectomy device may facilitate the safe and efficient revascularization of distal arterial embolic occlusions.

Investigation of Low-Pressure Turbine Endwall Flows: Simulations and Experiments (Postprint)

DTIC Science & Technology

2015-01-01

direction) minor semiaxis of 0.0417Cx (0.25in). Measured in the axial direction, the flat plate leading edge was located at x=-3.958Cx (23.75in) where...for public release; distribution unlimited. plate boundary layer is δ∗ = 1.721s/Re0.5s . For s = 4.833Cx, Reδ∗ = 1.721 √ s/CxRe = 1, 200. At this...boundary which was located at x=-1.4Cx. The following approximations hold for a turbulent flat plate boundary layer: δ99 = 0.37s Re0.2s , δ∗ = 0.046s

Lessons learned from the Space Flyer Unit (SFU) mission.

PubMed

Kuriki, Kyoichi; Ninomiya, Keiken; Takei, Mitsuru; Matsuoka, Shinobu

2002-11-01

The Space Flyer Unit (SFU) system and mission chronology are briefly introduced. Lessons learned from the SFU mission are categorized as programmatic and engineering lessons. In the programmatic category are dealt with both international and domestic collaborations. As for the engineering lessons safety design, orbital operation, in-flight anomaly, and post flight analyses are the major topics reviewed. c2002 Elsevier Science Ltd. All rights reserved.

Programmatic Environmental Assessment, Francis E. Warren Air Force Base, Wyoming

DTIC Science & Technology

2005-12-17

disturbance negatively affected wetlands along these drainages: old refuse dumps were established and remain along portions of Crow Creek, and growth of...avense), common hound’s tongue (Cynoglossum officinale ), field Programmatic Environmental Assessment F. E. Warren AFB 68 bindweed (Convolvulus...finding its way into the sewer through inflow and infiltration. In terms of total flow capacity, the sanitary sewer system can support moderate growth

Predicting re-victimization of battered women 3 years after exiting a shelter program.

PubMed

Bybee, Deborah; Sullivan, Cris M

2005-09-01

This study examined interpersonal and ecological predictors of re-victimization of a sample of women with abusive partners. All women (N = 124) had sought refuge from a battered women's shelter 3 years earlier, and half the sample had been randomly assigned to receive free, short-term advocacy services immediately upon exit from the shelter. Results 2 years post-intervention revealed positive change in the lives of participants (C. M. Sullivan & D. Bybee, 1999), including a decrease in abuse for women who had worked with advocates. The current study examined intervention effects 3 years after the program ended, as well as other predictors of re-abuse. Nineteen percent of the original sample had experienced domestic violence between 2 and 3 years after shelter exit (65% by current partners, 35% by ex-partners). The advocacy program's effect on risk of re-victimization did not continue 3 years post-intervention. However, having worked with an advocate 3 years prior continued to have a positive impact on women's quality of life and level of social support. The risk of being abused 3 years post-shelter stay was exacerbated by a number of factors present 1 year prior, including women's (1) having experienced abuse in the 6 months before that point; (2) having difficulties accessing resources; (3) having problems with the state welfare system; and (4) having people in their social networks who made their lives difficult. Women were at less risk of abuse if, 1 year earlier, they (1) were employed; (2) reported higher quality of life; and (3) had people in their networks who provided practical help and/or were available to talk about personal matters. These findings support the hypothesis that access to resources and social support serve as protective factors against continued abuse.

Re-entry using anatomically determined isthmuses: a curable ventricular tachycardia in repaired congenital heart disease.

PubMed

Kapel, Gijsbert F L; Reichlin, Tobias; Wijnmaalen, Adrianus P; Piers, Sebastiaan R D; Holman, Eduard R; Tedrow, Usha B; Schalij, Martin J; Stevenson, William G; Zeppenfeld, Katja

2015-02-01

Ventricular tachycardia (VT) is an important cause of late morbidity and mortality in repaired congenital heart disease. The substrate often includes anatomic isthmuses that can be transected by radiofrequency catheter ablation similar to isthmus block for atrial flutter. This study evaluates the long-term efficacy of isthmus block for treatment of re-entry VT in adults with repaired congenital heart disease. Thirty-four patients (49±13 years; 74% male) with repaired congenital heart disease who underwent radiofrequency catheter ablation of VT in 2 centers were included. Twenty-two (65%) had a preserved left and right ventricular function. Patients were inducible for 1 (interquartile range, 1-2) VT, median cycle length: 295 ms (interquartile range, 242-346). Ablation aimed to transect anatomic isthmuses containing VT re-entry circuit isthmuses. Procedural success was defined as noninducibility of any VT and transection of the anatomic isthmus and was achieved in 25 (74%) patients. During long-term follow-up (46±29 months), all patients with procedural success (18/25 with internal cardiac defibrillators) were free of VT recurrence but 7 of 18 experienced internal cardiac defibrillator-related complications. One patient with procedural success and depressed cardiac function received an internal cardiac defibrillator shock for ventricular fibrillation. None of the 18 patients (12/18 with internal cardiac defibrillators) with complete success and preserved cardiac function experienced any ventricular arrhythmia. In contrast, VT recurred in 4 of 9 patients without procedural success. Four patients died from nonarrhythmic causes. In patients with repaired congenital heart disease with preserved ventricular function and isthmus-dependent re-entry, VT isthmus ablation can be curative. © 2014 American Heart Association, Inc.

Construct validity of the LapVR virtual-reality surgical simulator.

PubMed

Iwata, Naoki; Fujiwara, Michitaka; Kodera, Yasuhiro; Tanaka, Chie; Ohashi, Norifumi; Nakayama, Goro; Koike, Masahiko; Nakao, Akimasa

2011-02-01

Laparoscopic surgery requires fundamental skills peculiar to endoscopic procedures such as eye-hand coordination. Acquisition of such skills prior to performing actual surgery is highly desirable for favorable outcome. Virtual-reality simulators have been developed for both surgical training and assessment of performance. The aim of the current study is to show construct validity of a novel simulator, LapVR (Immersion Medical, San Jose, CA, USA), for Japanese surgeons and surgical residents. Forty-four subjects were divided into the following three groups according to their experience in laparoscopic surgery: 14 residents (RE) with no experience in laparoscopic surgery, 14 junior surgeons (JR) with little experience, and 16 experienced surgeons (EX). All subjects executed "essential task 1" programmed in the LapVR, which consists of six tasks, resulting in automatic measurement of 100 parameters indicating various aspects of laparoscopic skills. Time required for each task tended to be inversely correlated with experience in laparoscopic surgery. For the peg transfer skill, statistically significant differences were observed between EX and RE in three parameters, including total time and average time taken to complete the procedure and path length for the nondominant hand. For the cutting skill, similar differences were observed between EX and RE in total time, number of unsuccessful cutting attempts, and path length for the nondominant hand. According to the programmed comprehensive evaluation, performance in terms of successful completion of the task and actual experience of the participants in laparoscopic surgery correlated significantly for the peg transfer (P=0.007) and cutting skills (P=0.026). The peg transfer and cutting skills could best distinguish between EX and RE. This study is the first to provide evidence that LapVR has construct validity to discriminate between novice and experienced laparoscopic surgeons.

Comparison of three different dressings for partial thickness burns in children: study protocol for a randomised controlled trial.

PubMed

Gee Kee, Emma; Kimble, Roy M; Cuttle, Leila; Stockton, Kellie

2013-11-25

In the paediatric population, pain and distress associated with burn injuries during wound care procedures remain a constant challenge. Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. Therefore, for paediatric patients in particular, identifying silver dressings that are associated with lower levels of pain and rapid wound re-epithelialisation is imperative. This study will determine whether there is a difference in time to re-epithelialisation and pain and distress experienced during wound care procedures among Acticoat™, Acticoat™ combined with Mepitel™ and Mepilex Ag™ dressings for acute, paediatric partial thickness burns. Children aged 0 to 15 years with an acute partial thickness (superficial partial to deep partial thickness inclusive) burn injury and a burn total body surface area of ≤ 10% will be eligible for the trial. Patients will be randomised to one of the three dressing groups: (1) Acticoat™ or (2) Acticoat™ combined with Mepitel™ or (3) Mepilex Ag™. A minimum of 28 participants will be recruited for each treatment group. Primary measures of pain, distress and healing will be repeated at each dressing change until complete wound re-epithelialisation occurs or skin grafting is required. Additional data collected will include infection status at each dressing change, physical function, scar outcome and scar management requirements, cost effectiveness of each dressing and staff perspectives of the dressings. The results of this study will determine the effects of three commonly used silver and silicone burn dressing combinations on the rate of wound re-epithelialisation and pain experienced during dressing procedures in acute, paediatric partial thickness burn injuries. Australian New Zealand Clinical Trials Registry ACTRN12613000105741.

Development of Guidelines for Identification of SCC Sites and Estimation of Re-Inspection Intervals for SCC Direct Assessment

DOT National Transportation Integrated Search

2010-05-31

This report describes the development of a series of guidelines for the identification of SCC sites and the estimation of re-inspection intervals. These SCC Guidelines are designed to complement and supplement existing SCC Direct Assessment protocols...

The effects of solar radiation and black body re-radiation on thermal comfort.

PubMed

Hodder, Simon; Parsons, Ken

2008-04-01

When the sun shines on people in enclosed spaces, such as in buildings or vehicles, it directly affects thermal comfort. There is also an indirect effect as surrounding surfaces are heated exposing a person to re-radiation. This laboratory study investigated the effects of long wave re-radiation on thermal comfort, individually and when combined with direct solar radiation. Nine male participants (26.0 +/- 4.7 years) took part in three experimental sessions where they were exposed to radiation from a hot black panel heated to 100 degrees C; direct simulated solar radiation of 600 Wm(-2) and the combined simulated solar radiation and black panel radiation. Exposures were for 30 min, during which subjective responses and mean skin temperatures were recorded. The results showed that, at a surface temperature of 100 degrees C (close to maximum in practice), radiation from the flat black panel provided thermal discomfort but that this was relatively small when compared with the effects of direct solar radiation. It was concluded that re-radiation, from a dashboard in a vehicle, for example, will not have a major direct influence on thermal comfort and that existing models of thermal comfort do not require a specific modification. These results showed that, for the conditions investigated, the addition of re-radiation from internal components has an effect on thermal sensation when combined with direct solar radiation. However, it is not considered that it will be a major factor in a real world situation. This is because, in practice, dashboards are unlikely to maintain very high surface temperatures in vehicles without an unacceptably high air temperature. This study quantifies the contribution of short- and long-wave radiation to thermal comfort. The results will aid vehicle designers to have a better understanding of the complex radiation environment. These include direct radiation from the sun as well as re-radiation from the dashboard and other internal surfaces.

Maintaining health sector collaborations between United States non-governmental organizations and North Korea through innovation and planning.

PubMed

Yim, Eugene S; Choi, Ricky Y; VanRooyen, Michael

2009-01-01

Humanitarian agencies in North Korea operate within a complex sociopolitical environment historically characterized by a baseline of mistrust. As a result of operating within such a heated environment, health sector collaborations between such agencies and the North Korean government have followed unpredictable courses. The factors that have contributed to successful programmatic collaborations, as perceived by United States non-governmental organizations (NGOs) and North Korean officials were investigated. A qualitative, multi-case, comparative, research design using semistructured interviews was used. Expert North Korean informants were interviewed to generate a list of factors contributing to programmatic success, defined as fulfilling mutually established objectives through collaboration. The North Korean informants were asked to identify US NGOs that fulfill these criteria ("mission-compatible NGOs"). Representatives from all of the mission compatible NGOs were interviewed. All informants provided their perspectives on the factors that contributed to successful programmatic collaborations. The interviews were recorded, transcribed, and analyzed for thematic content. North Korean informants identified six mission-compatible US NGOs. The North Korean and US NGO informants provided a number of factors that contributed to successful programs. These factors were grouped into the following themes: (1) responsiveness to North Korean requests; (2) resident status; (3) program monitoring; (4) sincerity (apolitical objectives); (5) information gathering; and (6) interagency collaboration. Some US NGOs have devised innovative measures to work within a unique set of parameters in North Korea. Both US NGOs and North Korean authorities have made significant concessions to maintain their programmatic partnerships. In this manner, seasoned collaborators have employed creative strategies and a form of health diplomacy to facilitate programmatic success in North Korea by building trust within a complex sociopolitical space.

A comprehensive space management model for facilitating programmatic research.

PubMed

Libecap, Ann; Wormsley, Steven; Cress, Anne; Matthews, Mary; Souza, Angie; Joiner, Keith A

2008-03-01

In FY04, the authors developed and implemented models to manage existing and incremental research space, and to facilitate programmatic research, at the University of Arizona College of Medicine. Benchmarks were set for recovery of total sponsored research dollars and for facilities and administrative (F&A) dollars/net square foot (nsf) of space, based on college-wide metrics. Benchmarks were applied to units (departments, centers), rather than to individual faculty. Performance relative to the benchmark was assessed using three-year moving averages, and applied to existing blocks of space. Space was recaptured or allocated, in all cases to programmatic themes, using uniform policies. F&A revenues were returned on the basis of performance relative to a benchmark. During the first two years after implementation of the model (FY05 and FY06), and for the 24 units occupying research space, median total sponsored research revenue/nsf increased from $393.96 to $474.46 (20.4%), and median F&A revenue/nsf increased from $57.42 to $91.86 (60.0%). These large increases in median values are driven primarily from redistribution and recapturing of space. Recruiting policies for unit heads were developed to facilitate joint hires among units. In combination, these policies created a comprehensive space management model for facilitating programmatic research. Although challenges remain in implementing the programmatic recruitment strategy, and selected modifications to the original policy were introduced later (e.g., research space for newly recruited junior faculty is now exempted from calculations for three years), overall, the models have created a climate of transparency that is now accepted and that allows efficient and equitable management of research space.

The Lummi Indians - Economic Development and Social Continuity.

ERIC Educational Resources Information Center

Stein, Barry

Focusing upon the developmental changes that have taken place among the Lummis of Washington between 1966 and the present, this case study of an American Indian tribe experiencing an economic renaissance emphasizes the fact that success can and does bring unintended risks. Specifically, this study presents information re: (1) the present (emphasis…

Seriously Data-Driven Decision Making

ERIC Educational Resources Information Center

Casserly, Michael D.

2011-01-01

As states approach the funding cliff marking the end of federal stimulus help for education, school districts will be feeling more financial pain than they're experiencing now. But there's good news amid the bad: Big city districts are showing schools nationwide a way to save money and improve efficiency by working together. They've created the…

"Do You Know What You're Doing?" College Students' Experiences with Male Condoms

ERIC Educational Resources Information Center

Yarber, William L.; Graham, Cynthia A.; Sanders, Stephanie A.; Crosby, Richard A.; Butler, Scott M.; Hartzell, Rose M.

2007-01-01

Background: Although quantitative assessment of male condom use errors and problems has received increased research attention, few studies have qualitatively examined this sexual health behavior. Purpose: This study examined problems of male condom use as experienced by college men and women at a large, public Midwestern university. Methods:…

Re-Thinking Support: The Hidden School-to-Work Challenges for Individuals with Special Needs

ERIC Educational Resources Information Center

Nag, Sonali

2011-01-01

This paper examines the hidden challenges experienced by individuals with special needs during the transition years between school and work. An assessment framework is proposed that covers domains of difficulties, developmental tasks during the transition years, the matrix of support within the home-community-institutions ecosystems, and the…

Debates in Religious Education. The Debates in Subject Teaching Series

ERIC Educational Resources Information Center

Barnes, L. Philip, Ed.

2011-01-01

What are the key debates in Religious Education teaching today? "Debates in Religious Education" explores the major issues all RE teachers encounter in their daily professional lives. It encourages critical reflection and aims to stimulate both novice and experienced teachers to think more deeply about their practice, and link research…

Intrusive Thoughts and Young Children's Knowledge about Thinking following a Natural Disaster

ERIC Educational Resources Information Center

Sprung, Manuel; Harris, Paul L.

2010-01-01

Background: "Hurricane Katrina" devastated the Mississippi Gulf Coast in August 2005. Intrusive re-experiencing is a common posttraumatic stress symptom. However, young children with limited introspection skills might have difficulties identifying their intrusive thoughts. Method: A sample of 165 5- to 9-year-old children were surveyed about their…

An Analysis of Secondary Schools' Crisis Management Preparedness: National Implications

ERIC Educational Resources Information Center

Adams, Cheantel M.; Kritsonis, William Allan

2006-01-01

The purpose of this study is to analyze crisis management plans of schools that have experienced crisis situations in the past. The plans used by these schools to manage these crisis situations will be evaluated for their effectiveness or ineffectiveness in re-establishing stability to their organization. With such information, other schools may…

A re-examination of the pollinator crisis.

PubMed

Martin, Cyrus

2015-10-05

Reports of colony collapse disorder in bees and studies showing the toxicity of neonicotinoid pesticides have led to claims that we are experiencing a pollinator crisis. As Cyrus Martin reports, however, the issue is complex with threats to bees being multifold and the status of populations unclear due to a surprising lack of data.

Perceptual processing advantages for trauma-related visual cues in post-traumatic stress disorder

PubMed Central

Kleim, B.; Ehring, T.; Ehlers, A.

2012-01-01

Background Intrusive re-experiencing in post-traumatic stress disorder (PTSD) comprises distressing sensory impressions from the trauma that seem to occur ‘out of the blue’. A key question is how intrusions are triggered. One possibility is that PTSD is characterized by a processing advantage for stimuli that resemble those that accompanied the trauma, which would lead to increased detection of such cues in the environment. Method We used a blurred picture identification task in a cross-sectional (n=99) and a prospective study (n=221) of trauma survivors. Results Participants with acute stress disorder (ASD) or PTSD, but not trauma survivors without these disorders, identified trauma-related pictures, but not general threat pictures, better than neutral pictures. There were no group differences in the rate of trauma-related answers to other picture categories. The relative processing advantage for trauma-related pictures correlated with re-experiencing and dissociation, and predicted PTSD at follow-up. Conclusions A perceptual processing bias for trauma-related stimuli may contribute to the involuntary triggering of intrusive trauma memories in PTSD. PMID:21733208

Space station needs, attributes and architectural options study. Volume 4: Architectural options, subsystems, technology and programmatics

NASA Technical Reports Server (NTRS)

1983-01-01

Space station architectural options, habitability considerations and subsystem analyses, technology, and programmatics are reviewed. The methodology employed for conceiving and defining space station concepts is presented. As a result of this approach, architectures were conceived and along with their supporting rationale are described within this portion of the report. Habitability consideration and subsystem analyses describe the human factors associated with space station operations and includes subsections covering (1) data management, (2) communications and tracking, (3) environmental control and life support, (4) manipulator systems, (5) resupply, (6) pointing, (7) thermal management and (8) interface standardization. A consolidated matrix of subsystems technology issues as related to meeting the mission needs for a 1990's era space station is presented. Within the programmatics portion, a brief description of costing and program strategies is outlined.

Rhenium-osmium isotope systematics of Group 2A and Group 4A iron meteorites

NASA Technical Reports Server (NTRS)

Creaser, R. A.; Papanastassiou, D. A.; Wasserburg, G. J.

1993-01-01

We are investigating the Re-Os isotope systematics of two groups of magmatic iron meteorites (2A, 4A) in an attempt to establish precise 'total rock' isochrons by the Re-Os system. The Re-187/Os-187 isotope system is recognized as a method by which the ages of iron meteorites can be directly determined and that can provide information on the timing of FeNi segregation and core formation in planetesimals. The Re-Os isotope system permits the direct absolute dating of the metal phase in iron meteorites. Indirect dating of iron meteorites has been achieved in the past through the Rb-Sr, K-Ar, and most recently, Sm-Nd for silicate inclusions, where present. Relative dating has been obtained directly by extensive studies of the short-lived system Pd-107/Ag-107 for the metal and sulfide phases and indirectly using I-129/Xe-129 in silicate and sulfide inclusions.

Factors Associated with Pregnant Women’s Anticipations and Experiences of HIV-related Stigma in Rural Kenya

PubMed Central

Cuca, Yvette P.; Onono, Maricianah; Bukusi, Elizabeth; Turan, Janet M.

2012-01-01

Pregnant women who fear or experience HIV-related stigma may not get care for their own health or medications to reduce perinatal transmission of HIV. This study examined factors associated with anticipating and experiencing HIV-related stigma among 1,777 pregnant women attending antenatal care clinics in rural Kenya. Women were interviewed at baseline, offered HIV testing and care, and a sub-set was re-interviewed at 4–8 weeks postpartum. Women who were older, had less education, whose husbands had other wives, and who perceived community discrimination against people with HIV had significantly greater adjusted odds of anticipating HIV stigma. Over half of the HIV-positive women interviewed postpartum reported having experienced stigma, much of which was self-stigma. Women experiencing minor depression, and those whose family knew of their HIV status had significantly greater adjusted odds of experiencing stigma. Lack of women’s empowerment, as well as depression, may be important risk factors for HIV-related stigma and discrimination. PMID:22799618

Coupling Legacy and Contemporary Deterministic Codes to Goldsim for Probabilistic Assessments of Potential Low-Level Waste Repository Sites

NASA Astrophysics Data System (ADS)

Mattie, P. D.; Knowlton, R. G.; Arnold, B. W.; Tien, N.; Kuo, M.

2006-12-01

Sandia National Laboratories (Sandia), a U.S. Department of Energy National Laboratory, has over 30 years experience in radioactive waste disposal and is providing assistance internationally in a number of areas relevant to the safety assessment of radioactive waste disposal systems. International technology transfer efforts are often hampered by small budgets, time schedule constraints, and a lack of experienced personnel in countries with small radioactive waste disposal programs. In an effort to surmount these difficulties, Sandia has developed a system that utilizes a combination of commercially available codes and existing legacy codes for probabilistic safety assessment modeling that facilitates the technology transfer and maximizes limited available funding. Numerous codes developed and endorsed by the United States Nuclear Regulatory Commission and codes developed and maintained by United States Department of Energy are generally available to foreign countries after addressing import/export control and copyright requirements. From a programmatic view, it is easier to utilize existing codes than to develop new codes. From an economic perspective, it is not possible for most countries with small radioactive waste disposal programs to maintain complex software, which meets the rigors of both domestic regulatory requirements and international peer review. Therefore, re-vitalization of deterministic legacy codes, as well as an adaptation of contemporary deterministic codes, provides a creditable and solid computational platform for constructing probabilistic safety assessment models. External model linkage capabilities in Goldsim and the techniques applied to facilitate this process will be presented using example applications, including Breach, Leach, and Transport-Multiple Species (BLT-MS), a U.S. NRC sponsored code simulating release and transport of contaminants from a subsurface low-level waste disposal facility used in a cooperative technology transfer project between Sandia National Laboratories and Taiwan's Institute of Nuclear Energy Research (INER) for the preliminary assessment of several candidate low-level waste repository sites. Sandia National Laboratories is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under Contract DE AC04 94AL85000.

Did Vertigo Kill America's Forgotten Astronaut?

NASA Technical Reports Server (NTRS)

Bendrick, Gregg A.; Merlin, Peter W.

2007-01-01

On November 15, 1967, U.S. Air Force test pilot Major Michael J. Adams was killed while flying the X-15 rocket-propelled research vehicle in a parabolic spaceflight profile. This flight was part of a joint effort with NASA. An electrical short in one of the experiments aboard the vehicle caused electrical transients, resulting in excessive workload by the pilot. At altitude Major Adams inappropriately initiated a flat spin that led to a series of unusual aircraft attitudes upon atmospheric re-entry, ultimately causing structural failure of the airframe. Major Adams was known to experience vertigo (i.e. spatial disorientation) while flying the X-15, but all X-15 pilots most likely experienced vertigo (i.e. somatogravic, or "Pitch-Up", illusion) as a normal physiologic response to the accelerative forces involved. Major Adams probably experienced vertigo to a greater degree than did others, since prior aeromedical testing for astronaut selection at Brooks AFB revealed that he had an unusually high degree of labyrinthine sensitivity. Subsequent analysis reveals that after engine burnout, and through the zenith of the flight profile, he likely experienced the oculoagravic ("Elevator") illusion. Nonetheless, painstaking investigation after the mishap revealed that spatial disorientation (Type II, Recognized) was NOT the cause, but rather, a contributing factor. The cause was in fact the misinterpretation of a dual-use flight instrument (i.e. Loss of Mode Awareness), resulting in confusion between yaw and roll indications, with subsequent flight control input that was inappropriate. Because of the altitude achieved on this flight, Major Adams was awarded Astronaut wings posthumously. Understanding the potential for spatial disorientation, particularly the oculoagravic illusion, associated with parabolic spaceflight profiles, and understanding the importance of maintaining mode awareness in the context of automated cockpit design, are two lessons that have direct application to the commercial space industry today.

Pre-attack symptomatology and temperament as predictors of children's responses to the September 11 terrorist attacks.

PubMed

Lengua, Liliana J; Long, Anna C; Smith, Kimberlee I; Meltzoff, Andrew N

2005-06-01

The aims of this study were to assess the psychological response of children following the September 11, 2001 terrorist attacks in New York and Washington, DC and to examine prospective predictors of children's post-attack responses. Children's responses were assessed in a community sample of children in Seattle, Washington, participating in an ongoing study. Symptomatology and temperament assessed prior to the attacks were examined as prospective predictors of post-attack post-traumatic stress (PTS), anxiety, depression and externalizing problems. Children demonstrated PTS symptoms and worries at levels comparable to those in children directly experiencing disasters, with 77% of children reporting being worried, 68% being upset by reminders, and 39% having upsetting thoughts. The most common PTS symptom cluster was re-experiencing, and 8% of children met criteria consistent with PTSD. African-American children reported more avoidant PTS symptoms and being more upset by the attacks than European-American children. Girls reported being more upset than boys. Prior internalizing, externalizing, social competence and self-esteem were related to post-attack PTS; and child inhibitory control, assessed prior to the 9/11 attacks, demonstrated a trend towards an association with post-attack PTS symptoms controlling for prior levels of symptomatology. PTS predicted child-report anxiety and conduct problem symptoms at follow-up, approximately 6 months after 9/11. Children experiencing a major disaster at a distance or indirectly through media exposure demonstrated worries and PTS symptoms suggesting that communities need to attend to children's mental health needs in response to national or regional disasters. Pre-disaster symptomatology or low self-regulation may render children more vulnerable in response to a disaster, and immediate post-disaster responses predict subsequent symptomatology. These variables might be used in the identification of children in need of intervention.

Systems Engineering Programmatic Estimation Using Technology Variance

NASA Technical Reports Server (NTRS)

Mog, Robert A.

2000-01-01

Unique and innovative system programmatic estimation is conducted using the variance of the packaged technologies. Covariance analysis is performed on the subsystems and components comprising the system of interest. Technological "return" and "variation" parameters are estimated. These parameters are combined with the model error to arrive at a measure of system development stability. The resulting estimates provide valuable information concerning the potential cost growth of the system under development.

The Impact of Nursing and Allied Health Professional Organizations and Accrediting Agencies on Community College Curricula. Proceedings of the Annual Conference of the National Council of Instructional Administrators (St. Louis, Missouri, April 4-7, 1982).

ERIC Educational Resources Information Center

American Association of Community and Junior Colleges, Washington, DC. National Council of Instructional Administrators.

The influence of professional accreditation on community college nursing and allied health curricula is discussed in these five papers. First, Robert Evans presents the community college viewpoint, distinguishing between general/institutional and programmatic accreditation, outlining the growth of programmatic accreditation, and citing as concerns…

New York Medical College Bioterrorism: CDM Disaster Medicine and Emerging Infections Training Center

DTIC Science & Technology

2013-10-01

format used in Science , Military Medicine, etc.). APPENDICES: Attach all appendices that contain information that supplements, clarifies or...included in supporting information. 8. PROGRAMMATIC SCIENCE /REVIEW (AUG 2010) (USAMRAA) The PI shall budget for, prepare for, and...participate in a programmatic/ science review, lasting not more than two days and including up to two overnight stays, for each year of the project’s term, at

JCL Implementation On A Human Spaceflight Program

NASA Technical Reports Server (NTRS)

Kulpa, Vyga; Karpowich, Mike; Abel, Diana; Archiable, Wes; Carson, William

2013-01-01

Joint Confidence Level (JCL) analysis focuses on the integration of traditionally stove-piped programmatic components (schedule, cost and risk) to establish projected resource and schedule requirements at various confidence levels and to identify programmatic cost and schedule risk drivers. SLS Program consists of multiple Prime Contractors managed by independent SLS Elements which are integrated using SE&I and Program Management. SLS further integrates with GSDO and MPCV through ESD integrated working groups.

Examining the relation between the serotonin transporter 5-HTTPLR genotype x trauma exposure interaction on a contemporary phenotypic model of posttraumatic stress symptomatology: A pilot study

PubMed Central

Pietrzak, Robert H.; Galea, Sandro; Southwick, Steven M.; Gelernter, Joel

2012-01-01

Background Little is known about the specificity of the interaction of serotonin transporter 5-HTTLPR genotype x trauma exposure in relation to contemporary structural models of PTSD symptomatology, which suggest that 4- or 5-factor models provide a better representation of this phenotypic expression of this disorder. Methods One hundred forty-nine respondents of a representative sample of adults affected by Hurricane Ike were interviewed 2 to 5 months after this 2008 disaster. Results After adjustment for age, sex, and ancestral proportion scores, the interaction of 5-HTTPLR genotype x trauma exposure was significantly associated with both severity (β=.40, p<.001) and probable diagnosis (Wald=4.55, p=.033; odds ratio=3.81, 95%CI=1.11–13.03) of Ike-related PTSD. Respondents with the low-expression variant of the 5-HTTPLR polymorphism (S allele) who were highly exposed to Hurricane Ike reported significantly greater severity of PTSD symptoms and were more likely to screen positive for PTSD than respondents homozygous for the L allele who were highly exposed to Hurricane Ike. Confirmatory factor analyses revealed that a 5-factor model of intercorrelated re-experiencing, avoidance, numbing, dysphoric arousal, and anxious arousal symptoms provided the best structural representation of PTSD symptomatology. The 5-HTTPLR genotype x exposure interaction was significant only for anxious arousal (β=.44, p<.001) and re-experiencing (β=.35, p<.001) symptoms, but not avoidance, numbing, or dysphoric arousal symptoms (all β’s≤.20, all p’s>.13). Limitations The small sample size and employment of self-report measures may limit generalizability of these findings. Conclusions Results of this pilot study suggest that the low-expression variant of the 5-HTTLPR polymorphism modifies risk for PTSD, but that this effect may be specific to anxious arousal and re-experiencing symptoms. PMID:23183127

Clinical application of a modular ankle robot for stroke rehabilitation.

PubMed

Forrester, Larry W; Roy, Anindo; Goodman, Ronald N; Rietschel, Jeremy; Barton, Joseph E; Krebs, Hermano Igo; Macko, Richard F

2013-01-01

Advances in our understanding of neuroplasticity and motor learning post-stroke are now being leveraged with the use of robotics technology to enhance physical rehabilitation strategies. Major advances have been made with upper extremity robotics, which have been tested for efficacy in multi-site trials across the subacute and chronic phases of stroke. In contrast, use of lower extremity robotics to promote locomotor re-learning has been more recent and presents unique challenges by virtue of the complex multi-segmental mechanics of gait. Here we review a programmatic effort to develop and apply the concept of joint-specific modular robotics to the paretic ankle as a means to improve underlying impairments in distal motor control that may have a significant impact on gait biomechanics and balance. An impedance controlled ankle robot module (anklebot) is described as a platform to test the idea that a modular approach can be used to modify training and measure the time profile of treatment response. Pilot studies using seated visuomotor anklebot training with chronic patients are reviewed, along with results from initial efforts to evaluate the anklebot's utility as a clinical tool for assessing intrinsic ankle stiffness. The review includes a brief discussion of future directions for using the seated anklebot training in the earliest phases of sub-acute therapy, and to incorporate neurophysiological measures of cerebro-cortical activity as a means to reveal underlying mechanistic processes of motor learning and brain plasticity associated with robotic training. Finally we conclude with an initial control systems strategy for utilizing the anklebot as a gait training tool that includes integrating an Internal Model-based adaptive controller to both accommodate individual deficit severities and adapt to changes in patient performance.

Clinical application of a modular ankle robot for stroke rehabilitation

PubMed Central

Forrester, Larry W.; Roy, Anindo; Goodman, Ronald N.; Rietschel, Jeremy; Barton, Joseph E.; Krebs, Hermano Igo; Macko, Richard F.

2015-01-01

Background Advances in our understanding of neuroplasticity and motor learning post-stroke are now being leveraged with the use of robotics technology to enhance physical rehabilitation strategies. Major advances have been made with upper extremity robotics, which have been tested for efficacy in multi-site trials across the subacute and chronic phases of stroke. In contrast, use of lower extremity robotics to promote locomotor re-learning has been more recent and presents unique challenges by virtue of the complex multi-segmental mechanics of gait. Objectives Here we review a programmatic effort to develop and apply the concept of joint-specific modular robotics to the paretic ankle as a means to improve underlying impairments in distal motor control that may have a significant impact on gait biomechanics and balance. Methods An impedance controlled ankle robot module (anklebot) is described as a platform to test the idea that a modular approach can be used to modify training and measure the time profile of treatment response. Results Pilot studies using seated visuomotor anklebot training with chronic patients are reviewed, along with results from initial efforts to evaluate the anklebot's utility as a clinical tool for assessing intrinsic ankle stiffness. The review includes a brief discussion of future directions for using the seated anklebot training in the earliest phases of sub-acute therapy, and to incorporate neurophysiological measures of cerebro-cortical activity as a means to reveal underlying mechanistic processes of motor learning and brain plasticity associated with robotic training. Conclusions Finally we conclude with an initial control systems strategy for utilizing the anklebot as a gait training tool that includes integrating an Internal Model-based adaptive controller to both accommodate individual deficit severities and adapt to changes in patient performance. PMID:23949045

Science Enabling Roles and Services of SPDF

NASA Technical Reports Server (NTRS)

McGuire, Robert E.; Bilitza, Dieter; Candey, Robert M.; Chimiak, Reine A.; Cooper, John F.; Garcia, Leonard N.; Harris, Bernard T.; Johnson, Rita C.; King, Joseph H.; Kovalick, Tamara J.;

Oxidation performance of platinum-clad Mo-47Re alloy

NASA Technical Reports Server (NTRS)

Clark, Ronald K.; Wallace, Terryl A.

1994-01-01

The alloy Mo-47Re has favorable mechanical properties at temperatures above 1400 C, but it undergoes severe oxidation when used in air with no protective coating. To shield the alloy from oxidation, platinum cladding has been evaluated. The unprotected alloy undergoes catastrophic oxidation under static and dynamic oxidation conditions. The platinum cladding provides good protection from static and dynamic oxidation for moderate times at 1260 C. Samples tested for longer times under static oxidation conditions experienced severe oxidation. The data suggest that oxidation results from the transport of oxygen through the grain boundaries and through the pinhole defects of the platinum cladding.

Trauma-related dreams of Australian veterans with PTSD: content, affect and phenomenology.

PubMed

Phelps, Andrea J; Forbes, David; Hopwood, Malcolm; Creamer, Mark

2011-10-01

Consensus on the parameters of trauma-related dreams required to meet criteria for post-traumatic stress disorder (PTSD) is critical when: (i) the diagnosis requires a single re-experiencing symptom; and (ii) trauma dreams are prevalent in survivors without PTSD. This study investigated the phenomenology of PTSD dreams in 40 veterans, using structured interview and self-report measures. Dream content varied between replay, non-replay, and mixed, but affect was largely the same as that experienced at the time of trauma across all dream types. ANOVA indicated no difference between dream types on PTSD severity or nightmare distress. The findings provide preliminary support for non-replay dreams to satisfy the DSM B2 diagnostic criterion when the affect associated with those dreams is the same as that experienced at the time of the traumatic event.

Violence to Others, Violent Self-Victimization, and Violent Victimization by Others Among Persons With a Mental Illness.

PubMed

Monahan, John; Vesselinov, Roumen; Robbins, Pamela Clark; Appelbaum, Paul S

2017-05-01

This research examined the frequency of and characteristics associated with three forms of violence among persons with mental illness-violence directed at others, self-directed violence, and violence directed at them by others. Previously unreported data from a follow-up sample of 951 patients from the MacArthur Violence Risk Assessment Study were analyzed to characterize involvement in violence directed at others, self-directed violence, and violence directed at them by others. Most patients (58%) experienced at least one form of violence, 28% experienced at least two forms, and 7% experienced all three forms. Several diagnostic, social, and historical variables distinguished the groups. Given the substantial overlap among the three forms of violence, clinicians should routinely screen patients who report one form for the occurrence of the other two. Co-occurrence of several forms of violence may require a package of interventions with components geared to each.

General Astrophysics with the HabEx Workhorse Camera

NASA Astrophysics Data System (ADS)

Stern, Daniel; Clarke, John; Gaudi, B. Scott; Kiessling, Alina; Krause, Oliver; Martin, Stefan; Scowen, Paul; Somerville, Rachel; HabEx STDT

2018-01-01

The Habitable Exoplanet Imaging Mission (HabEx) concept has been designed to enable an extensive suite of science, broadly put under the rubric of General Astrophysics, in addition to its exoplanet direct imaging science. General astrophysics directly addresses multiple NASA programmatic branches, and HabEx will enable investigations ranging from cosmology, to galaxy evolution, to stellar population studies, to exoplanet transit spectroscopy, to Solar System studies. This poster briefly describes one of the two primary HabEx General Astrophysics instruments, the HabEx Workhorse Camera (HWC). HWC will be a dual-detector UV-to-near-IR imager and multi-object grism spectrometer with a microshutter array and a moderate (3' x 3') field-of-view. We detail some of the key science we expect HWC to undertake, emphasizing unique capabilities enabled by a large-aperture, highly stable space-borne platform at these wavelengths.

Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells

PubMed Central

2013-01-01

Introduction Malignant pleural mesothelioma (MPM) is an incurable malignant disease, which results from chronic exposition to asbestos in at least 70% of the cases. Fibroblast activation protein (FAP) is predominantly expressed on the surface of reactive tumor-associated fibroblasts as well as on particular cancer types. Because of its expression on the cell surface, FAP is an attractive target for adoptive T cell therapy. T cells can be re-directed by retroviral transfer of chimeric antigen receptors (CAR) against tumor-associated antigens (TAA) and therefore represent a therapeutic strategy of adoptive immunotherapy. Methods To evaluate FAP expression immunohistochemistry was performed in tumor tissue from MPM patients. CD8+ human T cells were retrovirally transduced with an anti-FAP-F19-∆CD28/CD3ζ-CAR. T cell function was evaluated in vitro by cytokine release and cytotoxicity assays. In vivo function was tested with an intraperitoneal xenograft tumor model in immunodeficient mice. Results FAP was found to be expressed in all subtypes of MPM. Additionally, FAP expression was evaluated in healthy adult tissue samples and was only detected in specific areas in the pancreas, the placenta and very weakly for cervix and uterus. Expression of the anti-FAP-F19-∆CD28/CD3ζ-CAR in CD8+ T cells resulted in antigen-specific IFNγ release. Additionally, FAP-specific re-directed T cells lysed FAP positive mesothelioma cells and inflammatory fibroblasts in an antigen-specific manner in vitro. Furthermore, FAP-specific re-directed T cells inhibited the growth of FAP positive human tumor cells in the peritoneal cavity of mice and significantly prolonged survival of mice. Conclusion FAP re-directed CD8+ T cells showed antigen-specific functionality in vitro and in vivo. Furthermore, FAP expression was verified in all MPM histotypes. Therefore, our data support performing a phase I clinical trial in which MPM patients are treated with adoptively transferred FAP-specific re-directed T cells. PMID:23937772

Impact of Tumarkin attacks on complaints and work ability in Ménière's disease.

PubMed

Pyykkö, Ilmari; Manchaiah, Vinaya; Zou, Jing; Levo, Hilla; Kentala, Erna

2018-05-22

The purpose of the present study was to characterize the occurrence of Tumarkin attacks in patients with Ménière'sdisease (MD), and to study its association with reported complaints, severity of consequences, and also self-reported work ability. The study used a cross-sectional design. Data obtained from the Finnish Ménière Federation using an electronic survey was analyzed. 602 people with MD responded to the survey (62% response rate) with a mean age of 56.7 years and a mean duration of the disease 12.4 years. 49% of the respondents experienced Tumarkin attacks, which lasted for a few seconds to a few minutes. There were significant differences in complaints reported by MD patients with and without Tumarkin attacks. Respondents with Tumarkin attacks experienced various consequences, including tripping, falls, fear, anxiety, problems in dyadic life, and even transient loss of consciousness. Respondents with Tumarkin attacks had more frequently applied for pension than those not having Tumarkin attacks. On an average, respondents with Tumarkin attacks had less self-reported working ability when compared to those without Tumarkin attacks. The current study results suggest various differences in terms of complaints reported, severity of consequences, and the self-reported working ability in MD patients with and without Tumarkin attacks. Hearing healthcare professionals must examine Tumarkin attacks and their consequences in patients with MD during clinical examinations. In addition, the therapy should focus on alleviating the consequences and improving work ability.

Episodic Memory and Regional Atrophy in Frontotemporal Lobar Degeneration

PubMed Central

Söderlund, Hedvig; Black, Sandra E.; Miller, Bruce L.; Freedman, Morris; Levine, Brian

2008-01-01

It has been unclear to what extent memory is affected in frontotemporal lobar degeneration (FTLD). Since patients usually have atrophy in regions implicated in memory function, the frontal and/or temporal lobes, one would expect some memory impairment, and that the degree of atrophy in these regions would be inversely related to memory function. The purposes of this study were 1) to assess episodic memory function in FTLD, and more specifically patients' ability to episodically re-experience an event, and determine its source; 2) to examine whether memory performance is related to quantified regional brain atrophy. FTLD patients (n=18) and healthy comparison subjects (n=14) were assessed with cued recall, recognition, “remember/know” (self-reported re-experiencing) and source recall, at 30 min and 24 hr after encoding. Regional gray matter volumes were assessed with high resolution structural MRI concurrently to testing. Patients performed worse than comparison subjects on all memory measures. Gray matter volume in the left medial temporal lobe was positively correlated with recognition, re-experiencing, and source recall. Gray matter volume in the left posterior temporal lobe correlated significantly with recognition, at 30 min and 24 hr, and with source recall at 30 min. Estimated familiarity at 30 min was positively correlated with gray matter volume in the left inferior parietal lobe. In summary, episodic memory deficits in FTLD may be more common than previously thought, particularly in patients with left medial and posterior temporal atrophy. PMID:17888461

Programmatic Environmental Assessment Addressing the Development, Use, and Maintenance of Military Training Areas at Kirtland Air Force Base, New Mexico

DTIC Science & Technology

2016-09-30

design measures such as the use of “green” technology (e.g., photovoltaic panels, solar collection, heat recovery systems, wind turbines , green...Final Programmatic Environmental Assessment Addressing the Development, Use, and Maintenance of Military Training Areas at Kirtland Air Force...DEVELOPMENT, USE, AND MAINTENANCE OF MILITARY TRAINING AREAS AT KIRTLAND AIR FORCE BASE, NEW MEXICO Pursuant to provisions of the National

Department of Energy Programmatic Environmental Impact Statement (PEIS) scoping session

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-12-31

The purpose of this programmatic environmental impact statement (PEIS) scoping meeting was: to present the ground water program so as to build some familiarity and understanding about the issue involved; and to get the Durango community`s input. This report contains the presentations made by the project manager for the uranium mill tailings program, site manager for the Durango UMTRA site, manager of ground water hydrology, and includes comments made by local residents.

Draft Programmatic Environmental Impact Statement for Revision of the Coronado National Forest Land and Resource Management Plan: Cochise, Graham, Pima, Pinal, and Santa Cruz Counties, Arizona; Hidalgo County, New Mexico

Treesearch

Albert Peralta; Andrea Wargo Campbell; Ann Lynch; Cheri Bowen; Christopher Stetson; Craig Wilcox; Daniela Zormeier; Debby Kriegel; Delilah Jaworski; Dustin Walters; Eli Curiel; Erin Boyle; George McKay; Janet Moser; Jennifer Morrissey; Jennifer M. Ruyle; Jeremy Sautter; Judy York; Kenna Schoenle; Larry Jones; Laura White; Linda Peery; Mary Farrell; Mindi Lehew; Mindy Sue Vogel; Nicholas Laluk; Rachael Biggs; Robert Lefevre; Richard Gerhart; Salek Shafiqullah; Sara Dechter; Sarah Davis; Sharon Biedenbender; Tami Emmett; Terry Austin; William Gillespie; Yolynda Begay

2013-01-01

The U.S. Department of Agriculture, Forest Service, Coronado National Forest prepared this programmatic environmental impact statement to disclose the potential effects of a proposed action to revise the "Coronado National Forest Land and Resource Management Plan" (1986, as amended). The Coronado comprises 1,783,639 acres, most of which are located in...

Modeling PTSD Symptom Clusters, Alcohol Misuse, Anger, and Depression as They Relate to Aggression and Suicidality in Returning Veterans

PubMed Central

Hellmuth, Julianne C.; Stappenbeck, Cynthia A.; Hoerster, Katherine D.; Jakupcak, Matthew

2014-01-01

Suicidal ideation (SI) and aggression are common correlates of Posttraumatic Stress Disorder (PTSD) among Iraq and Afghanistan War veterans. The existing literature has established a strong link between these factors, but a more nuanced understanding of how PTSD influences them is needed. The current study examined the direct and indirect relationships between PTSD symptom clusters and SI and general aggression (without a specified target) via depression, alcohol misuse, and trait anger. Participants were 359 (92% male) Iraq/Afghanistan War veterans. Path analysis results suggest that the PTSD numbing cluster was directly (β=.28, p<.01.) and indirectly (β=.17, p=.001) related to SI through depression and the PTSD hyperarousal cluster was indirectly related to SI through depression (β=.13, p<.001). The PTSD re-experiencing cluster was directly related to aggression (β=.17, p<.05), whereas the PTSD numbing and hyperarousal clusters were indirectly related to aggression through trait anger (β=.05, p<.05; β=.20, p<.001). These findings suggest that adjunct treatments aimed at stabilizing anger, depression, and alcohol misuse may help clinicians ameliorate the maladaptive patterns often observed in returning Veterans. These results also point to specific manifestations of PTSD and co-occurring conditions that may inform clinicians in their attempts to identify at-risk veterans and facilitate preventative interventions. PMID:23073972

College Re-Culturing, Marketisation and Knowledge: The Meaning of Incorporation

ERIC Educational Resources Information Center

Smith, Rob

2015-01-01

The further education (FE) sector in England has experienced two decades of marketisation. This article takes as its focus the first five years of incorporation (1993-1998) for one case study college in a city ("Coppleton") in the West Midlands of England, five years that were dominated by a contract dispute. Data from interviews with…

Productivity and diversity of morel mushrooms in healthy, burned, and insect damaged forests of northeastern Oregon.

Treesearch

David Pilz; Nancy S. Weber; M. Carol Carter; Catherine G. Parks; Randy. Molina

2004-01-01

Large commercial crops of morels are harvested annually from montane coniferous forests of the Northwestern United States. Although some morels fruit annually in nondisturbed forests, others fruit copiously in areas experiencing fire, insect infestations, tree mortality, and soil disturbance. Many forest managers currently use thinning and prescribed fire to re-create...

Missing Stories, Missing Lives: Urban Girls (Re)Constructing Race and Gender in the Literacy Classroom.

ERIC Educational Resources Information Center

DeBlase, Gina L.

This study examined the ways in which eighth grade girls in an urban middle school constructed social identities through their experiences with literary texts. It focused on what sociocultural representations about female identity and gendered expectations emerged in the transactions in the literacy events these girls experienced in English class.…

(Re)thinking Equity: The Spatial and Racial Dynamics of Managing Learning and Learning to Manage

ERIC Educational Resources Information Center

Shore, Sue

2006-01-01

The vocational education and training (VET) sector has experienced substantial change in the past decade, characterised by ascendant industry-driven needs and mantras of flexibility and responsiveness. A number of public policies underpin these changes and simultaneously point to the need to manage diverse employing bodies, industry standards,…

Japanese Approaches to Organizational Internationalization of Universities: A Case Study of Three National University Corporations

ERIC Educational Resources Information Center

Watabe, Yuki

2010-01-01

This study aims to develop an understanding of the internationalization processes at universities in Japan by exploring a strategic model in internationally oriented universities. Universities in Japan have experienced university reform since the 1990s. The role and system of Japanese universities have been re-examined due to an emerging global…

Trust and Control: Public Administration and Risk Society

ERIC Educational Resources Information Center

Hoyer, Hans Christian; Wood, Elin Marit

2011-01-01

Today we live in a society with many choices and possibilities which were absent just a few decades ago. Knowledge is seen as temporary, and many paradoxes are experienced in the flow of information surrounding us. A basic insecurity can be seen as a consequence of this development. This paper re-thinks the consequences at the administrational and…

Adverse childhood experiences and sexual victimization in adulthood.

PubMed

Ports, Katie A; Ford, Derek C; Merrick, Melissa T

2016-01-01

Understanding the link between adverse childhood experiences (ACEs) and sexual victimization (SV) in adulthood may provide important information about the level of risk for adult SV and sexual re-victimization among childhood sexual abuse (CSA) survivors. In the present paper, we explore the relationship between ACEs, including CSA, and SV in adulthood. Data from the CDC-Kaiser ACE Study were used to examine the effect of experiences of early adversity on adult SV. Adult HMO members (n=7,272) undergoing a routine health exam provided detailed information about ACEs that occurred at age 18 or younger and their experiences of SV in adulthood. Analyses revealed that as ACE score increased, so did risk of experiencing SV in adulthood. Each of the ACE variables was significantly associated with adult SV, with CSA being the strongest predictor of adult SV. In addition, for those who reported CSA, there was a cumulative increase in adult SV risk with each additional ACE experienced. As such, early adversity is a risk factor for adult SV. In particular, CSA is a significant risk factor for sexual re-victimization in adulthood, and additional early adversities experienced by CSA survivors may heighten adult SV risk above and beyond the risk associated with CSA alone. Given the interconnectedness among various experiences of early adversity, adult SV prevention actions must consider how other violence-related and non-violence-related traumatic experiences may exacerbate the risk conferred by CSA on subsequent victimization. Published by Elsevier Ltd.

An investigation of war trauma types, symptom clusters, and risk-factors associated with post-traumatic stress disorder: where does gender fit?

PubMed

Farhood, Laila; Fares, Souha; Hamady, Carmen

2018-05-25

The female-male ratio in the prevalence of post-traumatic stress disorder (PTSD) is approximately 2:1. Gender differences in experienced trauma types, PTSD symptom clusters, and PTSD risk factors are unclear. We aimed to address this gap using a cross-sectional design. A sample of 991 civilians (522 women, 469 men) from South Lebanon was randomly selected in 2007, after the 2006 war. Trauma types were grouped into disaster and accident, loss, chronic disease, non-malignant disease, and violence. PTSD symptom clusters involved re-experiencing, avoidance, negative cognitions and mood, and arousal. These were assessed using parts I and IV of the Arabic version of the Harvard Trauma Questionnaire (HTQ). Risk factors were assessed using data from a social support and life events questionnaire in multiple regression models. Females were twice as likely as males to score above PTSD threshold (24.3 vs. 10.4%, p ˂ 0.001). Total scores on all trauma types were similar across genders. Females scored higher on all symptom clusters (p < 0.001). Social support, social life events, witnessed traumas, and domestic violence significantly were associated with PTSD in both genders. Social support, social life events, witnessed traumas and domestic violence were significantly associated with PTSD in both genders. Conversely, gender difference in experienced traumas was not statistically significant. These findings accentuate the need to re-consider the role of gender in the assessment and treatment of PTSD.

A severe hypersensitivity reaction to abacavir following re-challenge.

PubMed

Todd, Sej; Emerson, C R

2017-03-01

We report this case to highlight the possibility of a severe hypersensitivity reaction as an important potential consequence of couples, living with HIV, sharing anti-retroviral treatment. An HIV-1 positive and carrier of HLA-B*57:01 allele, treatment experienced man was commenced one pill Regimen Stribild (tenofovir, emtricitabine, elvitegravir and cobicistat) in July 2015. On running short of medication, he admitted to sharing his partner's treatment (Triumeq; abacavir, lamivudine and dolutegravir). On the second occasion, re-introduction resulted in whole body rash 4 h post dose and was associated with fever, respiratory symptoms, headache and vomiting. On examination, he was pyrexic, tachyponeic, tachycardiac and hypotensive. Hypersensitivity to abacavir can cause significant morbidity. Re-challenge can result in a more rapid, severe and potentially life-threatening reaction. This potentially could become an increasing problem with more couples, living with HIV, sharing medication.

Sociodemographic factors associated with female genital cutting among women of reproductive age in Nigeria.

PubMed

Ojo, T O; Ijadunola, M Y

2017-08-01

The aims of the study were to determine the prevalence of female genital cutting (FGC) among women of reproductive age in Nigeria and identify the sociodemographic factors associated with the practice. A secondary analysis of the 2013 Nigeria Demographic and Health Survey was carried out in 38,948 women of reproductive age (15-49 years). The prevalence of FGC among respondents was almost 25%, most of whom (82%) had undergone the procedure when they were under 5 years of age. Traditional circumcisers performed 72.2% of all procedures. Type 2 was the common form (62.6%) of FGC. Almost a quarter of respondents (23.1%) wanted the practice to continue. Women aged 45-49 years were approximately twice as likely to have undergone FGC compared with women aged 15-19 years (odds ratio [OR] 2.41; 95% confidence interval [CI] 1.99, 2.92; p < .001). Women from parts of Nigeria other than the North East zone were significantly more likely to have experienced FGC (p < .001). Women of Yoruba ethnicity were significantly more likely to have experienced FGC compared with women of Hausa/Fulani ethnicity (OR 4.86; 95% CI 3.03, 8.12; p < .001). Our findings have programmatic implications for ending the practice of FGC in Nigeria. Elimination efforts should be intensified among women of Yoruba ethnicity. To instigate behavioural change, communication interventions should particularly target residents in parts of Nigeria other than the North East zone.

Bricklayer Static Analysis

NASA Astrophysics Data System (ADS)

Harris, Christopher

In the U.S., science and math are taking spotlight in education, and rightfully so as they directly impact economic progression. Curiously absent is computer science, which despite its numerous job opportunities and growth does not have as much focus. This thesis develops a source code analysis framework using language translation, and machine learning classifiers to analyze programs written in Bricklayer for the purposes of programmatically identifying relative success or failure of a students Bricklayer program, helping teachers scale in the amount of students they can support, and providing better messaging. The thesis uses as a case study a set of student programs to demonstrate the possibilities of the framework.

Tooth wear risk assessment and care-planning in general dental practice.

PubMed

O'Toole, S; Khan, M; Patel, A; Patel, N J; Shah, N; Bartlett, D; Movahedi, S

2018-03-09

Objective To assess charting, risk assessment and treatment-planning of tooth wear between recently qualified and experienced dentists in general dental practice.Design Service evaluation.Setting Multi-setting evaluation of three mixed NHS/Private general dental practices in North-East London.Methods The clinical notes of new patient examinations on dentate adults presenting from the 1 October 2016 to 31 December 2016 were audited collecting data on tooth wear charting, risk assessment and treatment planning. Data were analysed using descriptives, chi square and logistic regressions in SPSS. Significance was inferred at p <0.05.Results Foundation dentists and experienced dentists performed 85 and 200 new patient examinations, respectively, during the evaluation period. Tooth wear was charted for 48% of those attending foundation dentists and 5% of those attending experienced dentists. Diet was assessed in 50.6% of patients examined by foundation dentists and 1.0% of patients examined by experienced dentists. Foundation dentists were more likely to chart tooth wear, risk assess and preventively manage tooth wear compared to experienced dentists (p <0.001).Conclusion This service evaluation highlights that improvements are required in recording, risk assessing and preventive treatment planning of erosive tooth wear. Experienced dentists were less likely to risk assess tooth wear and less likely to provide preventive treatment. Experienced GDPs may benefit from re-training in this area.

Post-traumatic Stress Disorder Symptoms Among People Living with HIV/AIDS in Rural China.

PubMed

Luo, Sitong; Lin, Chunqing; Ji, Guoping; Li, Li

2017-11-01

Among people living with HIV/AIDS (PLHA), the occurrence of post-traumatic stress disorder (PTSD) symptoms associated with HIV diagnosis is a common problem. This study examined HIV diagnosis-related PTSD symptoms and its associated factors among PLHA in rural China. We used baseline data from a randomized controlled trial conducted in Anhui Province, China. Surveys of 522 PLHA were conducted via computer-assisted personal interview method. PTSD symptoms were measured based on re-experiencing, avoidance and arousal of the day of HIV diagnosis. Association between PTSD symptoms and demographic characteristics, physical and social functioning were assessed by multiple regression analysis and structural equation modeling. Social functioning exhibited a direct association with HIV diagnosis-related PTSD symptoms, and also mediated the association between PTSD symptoms and age, family income, and physical functioning. The study findings underscore the importance of developing interventions that alleviate PTSD symptoms and improve social functioning among PLHA in rural China.

Main and interactive effects of a nonclinical panic attack history and distress tolerance in relation to PTSD symptom severity.

PubMed

Marshall-Berenz, Erin C; Vujanovic, Anka A; Zvolensky, Michael J

2011-03-01

The current study investigated the main and interactive effects of a nonclinical panic attack history and distress tolerance in relation to PTSD symptoms. The sample consisted of 91 adults (62.6% women; M(age)=23.45, SD=9.56) who met DSM-IV criteria for trauma exposure, 53.8% of whom met criteria for a recent (past 2 years) history of nonclinical panic attacks. Results indicated that distress tolerance, as measured by the Distress Tolerance Scale (Simons & Gaher, 2005), was significantly related to all PTSD symptom clusters, and a nonclinical panic attack history was significantly related to PTSD re-experiencing and hyperarousal symptoms. The interaction of a nonclinical panic attack history and distress tolerance significantly predicted unique variance in only PTSD hyperarousal symptoms. Implications and future directions are discussed for the role of nonclinical panic attacks and distress tolerance in PTSD symptom expression. Copyright © 2010 Elsevier Ltd. All rights reserved.

Strengthening the role of Community Health Representatives in the Navajo Nation.

PubMed

King, Caroline; Goldman, Alex; Gampa, Vikas; Smith, Casey; Muskett, Olivia; Brown, Christian; Malone, Jamy; Sehn, Hannah; Curley, Cameron; Begay, Mae-Gilene; Nelson, Adrianne Katrina; Shin, Sonya Sunhi

2017-04-21

Strengthening Community Health Worker systems has been recognized to improve access to chronic disease prevention and management efforts in low-resource communities. The Community Outreach and Patient Empowerment (COPE) Program is a Native non-profit organization with formal partnerships with both the Navajo Nation Community Health Representative (CHR) Program and the clinical facilities serving the Navajo Nation. COPE works to better integrate CHRs into the local health care system through training, strengthening care coordination, and a standardized culturally appropriate suite of health promotion materials for CHRs to deliver to high-risk individuals in their homes. The objective of this mixed methods, cross sectional evaluation of a longitudinal cohort study was to explore how the COPE Program has effected CHR teams over the past 6 years. COPE staff surveyed CHRs in concurrent years (2014 and 2015) about their perceptions of and experience working with COPE, including potential effects COPE may have had on communication among patients, CHRs, and hospital-based providers. COPE staff also conducted focus groups with all eight Navajo Nation CHR teams. CHRs and other stakeholders who viewed our results agree that COPE has improved clinic-community linkages, primarily through strengthened collaborations between Public Health Nurses and CHRs, and access to the Electronic Health Records. CHRs perceived that COPE’s programmatic support has strengthened their validity and reputation with providers and clients, and has enhanced their ability to positively effect health outcomes among their clients. CHRs report an improved ability to deliver health coaching to their clients. Survey results show that 80. 2% of CHRs feel strongly positive that COPE trainings are useful, while 44.6% of CHRs felt that communication and teamwork had improved because of COPE. These findings suggest that CHRs have experienced positive benefits from COPE through training. COPE may provide a useful programmatic model on how best to support other Community Health Workers through strengthening clinic-community linkages, standardizing competencies and training support, and structuring home-based interventions for high-risk individuals.

A successful programmatic structure and strategies to attract and educate students in earth and environmental sciences: an example from the University of Delaware, USA

NASA Astrophysics Data System (ADS)

Levia, Delphis

2013-04-01

The achievement of sustainable use of our natural world is one of the major issues confronting humankind today. Environmental issues are inherently complex and difficult to resolve. Successful resolution of our most pressing environmental problems, such as climate change and ocean acidification, will require well-trained earth and environmental scientists that think critically in a multi-dimensional framework at variable spatial and temporal scales. This begs the question as to how we can both attract and successfully educate students in such a way that will permit them to tackle the multitude of environmental problems currently facing society. This poster details one way to successfully attract and train students in an interdisciplinary environmental education framework by sharing: (1) some of the successful strategies and programmatic structure of the University of Delaware's undergraduate environmental programs that have grown over 60% in two years after a major programmatic revision; and (2) the current round of programmatic revisions that will complete the strategic planning process.* The interdisciplinary environmental education program at the University of Delaware has a strong programmatic core that provides students with the requisite quantitative training and field experience to solve complicated environmental issues. At the same time, the environmental program includes the social, political, and economic contexts of environmental issues. Together, these two parts of the core best equip students to mitigate environmental problems. Following a strategic planning effort, the University of Delaware is building upon past successes in training environmental scientists and managers by further reformulating its environmental programs to leverage the power of theme-based learning which complements the programmatic core in such a way to teach problem-solving skills. This poster details the multidimensional nature of the University of Delaware's environmental programs and the revised program structure that seeks to strike a balance between quantitative science, adaptive management, and solutions oriented thinking. ------------------------ *Please note that the planning process for the environmental programs was and is the collective effort of many dedicated people. Current members of the advisory Environmental Council include Drs. Delphis Levia (Program Director), Nancy Targett (Dean and Council Chair), Frank Newton, Tracy Deliberty, Tom Sims, John Madsen, Paul Imhoff, Jan Johnson, Jerry Kauffman, Murray Johnston.

The deep planetary magnetotail revisited

NASA Technical Reports Server (NTRS)

Macek, Wieslaw M.

1989-01-01

The magnetotail model of Grzedzielski and Macek (1988) is extended to great distances in the antisolar direction. For typical solar wind parameters at 1 AU and the most probable set of parameters of the model as determined for the ISEE-3 region of 200 earth radii, R(E), the open geotail extends to at least 3000 - 4000 R(E) downstream from earth, where it forms a cavity filled with a dense hot plasma and low magnetic field strengths. The cross section of this cavity in the plane perpendicular to the earth-sun line has dimensions of 300 - 400 R(E) parallel to the ecliptic plane, but only 5 R(E) in the direction normal to the ecliptic. It seems likely that the magnetotail would become filamentary at such distances.

Diurnal characteristics of ecosystem respiration of alpine meadow on the Qinghai-Tibetan Plateau: implications for carbon budget estimation.

PubMed

Qin, Yu; Yi, Shuhua

2013-01-01

Accurately estimating daily mean ecosystem respiration rate (Re) is important for understanding how ecosystem carbon budgets will respond to climate change. Usually, daily mean Re is represented by measurement using static chamber on alpine meadow ecosystems from 9:00 to 11:00 h a.m. local time directly. In the present study, however, we found that the calculated daily mean Re from 9:00 to 11:00 h a.m. local time was significantly higher than that from 0:00 to 23:30 h local time in an alpine meadow site, which might be caused by special climate condition on the Qinghai-Tibetan Plateau. Our results indicated that the calculated daily mean Re from 9:00 to 11:00 h a.m. local time cannot be used to represent daily mean Re directly.

A comparison of ballet dancers with different level of experience in performing single-leg stance on retiré position.

PubMed

Lin, Chia-Wei; Lin, Cheng-Feng; Hsue, Bih-Jen; Su, Fong-Chin

2014-04-01

The purpose of the current study was to evaluate the postural stability of single-leg standing on the retiré position in ballet dancers having three different levels of skill. Nine superior experienced female ballet dancers, 9 experienced, and 12 novice dancers performed single-leg standing in the retiré position. The parameters of center of pressure (COP) in the anterior-posterior and medial-lateral directions and the maximum distance between COP and the center of mass (COM) were measured. The inclination angles of body segments (head, torso, and supporting leg) in the frontal plane were also calculated. The findings showed that the novice dancers had a trend of greater torso inclination angles than the experienced dancers but that the superior experienced dancers had greater maximum COM-COP distance in the anterior-posterior direction. Furthermore, both experienced and novice dancers had better balance when standing on the nondominant leg, whereas the superior experienced dancers had similar postural stability between legs. Based on the findings, ballet training should put equal focus on both legs and frontal plane control (medial-lateral direction) should be integrated to ballet training program.

Design of Community Resource Inventories as a Component of Scalable Earth Science Infrastructure: Experience of the Earthcube CINERGI Project

NASA Astrophysics Data System (ADS)

Zaslavsky, I.; Richard, S. M.; Valentine, D. W., Jr.; Grethe, J. S.; Hsu, L.; Malik, T.; Bermudez, L. E.; Gupta, A.; Lehnert, K. A.; Whitenack, T.; Ozyurt, I. B.; Condit, C.; Calderon, R.; Musil, L.

2014-12-01

EarthCube is envisioned as a cyberinfrastructure that fosters new, transformational geoscience by enabling sharing, understanding and scientifically-sound and efficient re-use of formerly unconnected data resources, software, models, repositories, and computational power. Its purpose is to enable science enterprise and workforce development via an extensible and adaptable collaboration and resource integration framework. A key component of this vision is development of comprehensive inventories supporting resource discovery and re-use across geoscience domains. The goal of the EarthCube CINERGI (Community Inventory of EarthCube Resources for Geoscience Interoperability) project is to create a methodology and assemble a large inventory of high-quality information resources with standard metadata descriptions and traceable provenance. The inventory is compiled from metadata catalogs maintained by geoscience data facilities, as well as from user contributions. The latter mechanism relies on community resource viewers: online applications that support update and curation of metadata records. Once harvested into CINERGI, metadata records from domain catalogs and community resource viewers are loaded into a staging database implemented in MongoDB, and validated for compliance with ISO 19139 metadata schema. Several types of metadata defects detected by the validation engine are automatically corrected with help of several information extractors or flagged for manual curation. The metadata harvesting, validation and processing components generate provenance statements using W3C PROV notation, which are stored in a Neo4J database. Thus curated metadata, along with the provenance information, is re-published and accessed programmatically and via a CINERGI online application. This presentation focuses on the role of resource inventories in a scalable and adaptable information infrastructure, and on the CINERGI metadata pipeline and its implementation challenges. Key project components are described at the project's website (http://workspace.earthcube.org/cinergi), which also provides access to the initial resource inventory, the inventory metadata model, metadata entry forms and a collection of the community resource viewers.

A Policy Analysis of Using Unit Costs as a Means of Performance Measurement in the Air Force Science and Technology Program

DTIC Science & Technology

1991-09-01

demonstrate, is that there is more than one way to account for S &T costs and evaluate its program performance. The first option evaluated considers...Personal Communication. Wright Laboratory, Wright-Patterson AFB OH, 14 May 1991. Horngren , Charles T. and George Foster. Cost Accounting A Managerial...78 Programmatic Feedback ........ 79 S &T as Overhead............79 Scoring the Options............80 Unit Costs ................8 Programmatic

Client relations in South Asia: programmatic and societal determinants.

PubMed

Simmons, R; Koblinsky, M A; Phillips, J F

1986-01-01

Client relations constitute a neglected area of research in family planning. Findings from studies in northern India and Bangladesh reveal considerable variation in both the quantity and quality of contacts in programs that function under roughly comparable socioeconomic conditions. Client relations are determined by a complex set of forces in which both programmatic factors and conditions pertaining to the societal environment play a key role. Worker-client exchanges have a net, incremental effect on contraceptive use.

HFI Bolometer Detectors Programmatic CDR

NASA Technical Reports Server (NTRS)

Lange, Andrew E.

2002-01-01

Programmatic Critical Design Review (CDR) of the High Frequency Instrument (HFI) Bolometer Detector on the Planck Surveyor is presented. The topics include: 1) Scientific Requirements and Goals; 2) Silicon Nitride Micromesh 'Spider-Web' Bolometers; 3) Sub-Orbital Heritage: BOOMERANG; 4) Noise stability demonstrated in BOOMERANG; 5) Instrument Partners; 6) Bolometer Environment on Planck/HFI; 7) Bolometer Modules; and 8) Mechanical Interface. Also included are the status of the receivables and delivery plans with Europe. This paper is presented in viewgraph form.

Prioritization Methodology for Chemical Replacement

NASA Technical Reports Server (NTRS)

Cruit, W.; Schutzenhofer, S.; Goldberg, B.; Everhart, K.

1993-01-01

This project serves to define an appropriate methodology for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semiquantitative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weigh the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results are being implemented as a guideline for consideration for current NASA propulsion systems.

Developmental milestones across the programmatic life cycle: implementing the CDC's Colorectal Cancer Screening Demonstration Program.

PubMed

Glover-Kudon, Rebecca; DeGroff, Amy; Rohan, Elizabeth A; Preissle, Judith; Boehm, Jennifer E

2013-08-01

In 2005 through 2009, the Centers for Disease Control and Prevention (CDC) funded 5 sites to implement a colorectal cancer screening program for uninsured, low-income populations. These 5 sites composed a demonstration project intended to explore the feasibility of establishing a national colorectal cancer screening program through various service delivery models. A longitudinal, multiple case study was conducted to understand and document program implementation processes. Using metaphor as a qualitative analytic technique, evaluators identified stages of maturation across the programmatic life cycle. Analysis rendered a working theory of program development during screening implementation. In early stages, program staff built relationships with CDC and local partners around screening readiness, faced real-world challenges putting program policies into practice, revised initial program designs, and developed new professional skills. Midterm implementation was defined by establishing program cohesiveness and expanding programmatic reach. In later stages of implementation, staff focused on sustainability and formal program closeout, which prompted reflection about personal and programmatic accomplishments. Demonstration sites evolved through common developmental stages during screening implementation. Findings elucidate ways to target technical assistance to more efficiently move programs along their maturation trajectory. In practical terms, the time and cost associated with guiding a program to maturity may be potentially shortened to maximize return on investment for both organizations and clients receiving service benefits. © 2013 American Cancer Society.

Rhenium-osmium isotope systematics of carbonaceous chondrites

USGS Publications Warehouse

Walker, R.J.; Morgan, J.W.

1989-01-01

Rhenium and osmium concentrations and Os isotopic compositions of eight carbonaceous chondrites, one LL3 ordinary chondrite, and two iron meteorites were determined by resonance ionization mass spectrometry. Iron meteorite 187Re/186Os and 187OS/186Os ratios plot on the previously determined iron meteorite isochron, but most chondrite data plot 1 to 2 percent above this meteorite isochron. This suggests either that irons have significantly younger Re-Os closure ages than chondrites or that chondrites were formed from precursor materials with different chemical histories from the precursors of irons. Some samples of Semarkona (LL3) and Murray (C2M) meteorites plot 4 to 6 percent above the iron meteorite isochron, well above the field delineated by other chondrites. Murray may have lost Re by aqueous leaching during its preterrestrial history. Semarkona could have experienced a similar loss of Re, but only slight aqueous alteration is evident in the meteorite. Therefore, the isotopic composition of Semarkona could reflect assembly of isotopically heterogeneous components subsequent to 4.55 billion years ago or Os isotopic heterogeneities in the primordial solar nebula.

New Interest in Wild Forest Products in Europe as an Expression of Biocultural Dynamics.

PubMed

Wiersum, K F

2017-01-01

In Europe, interest in wild forest products is increasing. Such products may be interpreted in a biological sense as deriving from autonomously growing forest species or in a biocultural sense as reflecting dynamics in human living with biodiversity through re-wilding of earlier domesticated species. In this article I elaborate the idea that the new interests reflect biocultural dynamics. First, I identify these dynamics as involving both domestication and re-wilding and characterize these processes as involving biological, environmental, and cultural dimensions. Next, I present a comparative review of two approaches to re-wilding forest production in the Netherlands: meat production from new types of natural grazing systems, and food production from plants re-introduced to the wild. The first approach is based on the stimulation of naturally occurring ecological processes and the second on the stimulation of new forms of experiencing bio-cultural heritage. The examples demonstrate that the new interests in wild forest products involve both a return to earlier stages of domestication in an ecological sense and a new phase of acculturation to evolving socio-cultural conditions.

77 FR 36209 - Airworthiness Directives; Airbus Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

... number of the installed RAT actuator, and re-identification of the actuator and RAT, or replacement of the RAT actuator with a serviceable unit and re-identification of the RAT, if necessary. We are... number, and serial number of the installed RAT actuator, and re- identification of the actuator and RAT...

On the distribution of local dissipation scales in turbulent flows

NASA Astrophysics Data System (ADS)

May, Ian; Morshed, Khandakar; Venayagamoorthy, Karan; Dasi, Lakshmi

2014-11-01

Universality of dissipation scales in turbulence relies on self-similar scaling and large scale independence. We show that the probability density function of dissipation scales, Q (η) , is analytically defined by the two-point correlation function, and the Reynolds number (Re). We also present a new analytical form for the two-point correlation function for the dissipation scales through a generalized definition of a directional Taylor microscale. Comparison of Q (η) predicted within this framework and published DNS data shows excellent agreement. It is shown that for finite Re no single similarity law exists even for the case of homogeneous isotropic turbulence. Instead a family of scaling is presented, defined by Re and a dimensionless local inhomogeneity parameter based on the spatial gradient of the rms velocity. For moderate Re inhomogeneous flows, we note a strong directional dependence of Q (η) dictated by the principal Reynolds stresses. It is shown that the mode of the distribution Q (η) significantly shifts to sub-Kolmogorov scales along the inhomogeneous directions, as in wall bounded turbulence. This work extends the classical Kolmogorov's theory to finite Re homogeneous isotropic turbulence as well as the case of inhomogeneous anisotropic turbulence.

Direct numerical simulation of flow around a surface-mounted finite square cylinder at low Reynolds numbers

NASA Astrophysics Data System (ADS)

Zhang, Di; Cheng, Liang; An, Hongwei; Zhao, Ming

2017-04-01

With the aid of direct numerical simulation, this paper presents a detailed investigation on the flow around a finite square cylinder at a fixed aspect ratio (AR) of 4 and six Reynolds numbers (Re = 50, 100, 150, 250, 500, and 1000). It is found that the mean streamwise vortex structure is also affected by Re, apart from the AR value. Three types of mean streamwise vortices have been identified and analyzed in detail, namely, "Quadrupole Type" at Re = 50 and Re = 100, "Six-Vortices Type" at Re = 150 and Re = 250, and "Dipole Type" at Re = 500 and Re = 1000. It is the first time that the "Six-Vortices Type" mean streamwise vortices are reported, which is considered as a transitional structure between the other two types. Besides, three kinds of spanwise vortex-shedding models have been observed in this study, namely, "Hairpin Vortex Model" at Re = 150, "C and Reverse-C and Hairpin Vortex Model (Symmetric Shedding)" at Re = 250, and "C and Reverse-C and Hairpin Vortex Model (Symmetric/Antisymmetric Shedding)" at Re = 500 and Re = 1000. The newly proposed "C and Reverse-C and Hairpin Vortex Model" shares some similarities with "Wang's Model" [H. F. Wang and Y. Zhou, "The finite-length square cylinder near wake," J. Fluid Mech. 638, 453-490 (2009)] but differs in aspects such as the absence of the connection line near the free-end and the "C-Shape" vortex structure in the early stage of the formation of the spanwise vortex.

A qualitative evaluation of the 2005–2011 National Academic Centers of Excellence in Youth Violence Prevention Program☆

PubMed Central

Holland, Kristin M.; Vivolo-Kantor, Alana M.; Cruz, Jason Dela; Massetti, Greta M.; Mahendra, Reshma

2018-01-01

The Centers for Disease Control and Prevention’s Division of Violence Prevention (DVP) funded eight National Academic Centers of Excellence (ACEs) in Youth Violence Prevention from 2005 to 2010 and two Urban Partnership Academic Centers of Excellence (UPACEs) in Youth Violence Prevention from 2006 to 2011. The ACEs and UPACEs constitute DVP’s 2005–2011 ACE Program. ACE Program goals include partnering with communities to promote youth violence (YV) prevention and fostering connections between research and community practice. This article describes a qualitative evaluation of the 2005–2011 ACE Program using an innovative approach for collecting and analyzing data from multiple large research centers via a web-based Information System (ACE-IS). The ACE-IS was established as an efficient mechanism to collect and document ACE research and programmatic activities. Performance indicators for the ACE Program were established in an ACE Program logic model. Data on performance indicators were collected through the ACE-IS biannually. Data assessed Centers’ ability to develop, implement, and evaluate YV prevention activities. Performance indicator data demonstrate substantial progress on Centers’ research in YV risk and protective factors, community partnerships, and other accomplishments. Findings provide important lessons learned, illustrate progress made by the Centers, and point to new directions for YV prevention research and programmatic efforts. PMID:26319174

Moving Forward by Looking Back: Reflecting on a Decade of CDC's Work in Sexual Violence Prevention, 2000–2010

PubMed Central

Simon, Thomas R.; Basile, Kathleen C.; Yee, Sue Lin; Lang, Karen; Spivak, Howard

2012-01-01

Abstract In 2011, the Division of Violence Prevention (DVP) within CDC's Injury Center engaged an external panel of experts to review and evaluate its research and programmatic portfolio for sexual violence (SV) prevention from 2000 to 2010. This article summarizes findings from the review by highlighting DVP's key activities and accomplishments during this period and identifying remaining gaps in the field and future directions for SV prevention. DVP's SV prevention work in the 2000s included (1) raising the profile of SV as a public health problem, (2) shifting the field toward a focus on the primary prevention of SV perpetration, and (3) applying the public health model to SV research and programmatic activities. The panel recommended that DVP continue to draw attention to the importance of sexual violence prevention as a public health issue, build on prior investments in the Rape Prevention and Education Program, support high-quality surveillance and research activities, and enhance communication to improve the link between research and practice. Current DVP projects and priorities provide a foundation to actively address these recommendations. In addition, DVP continues to provide leadership and guidance to the research and practice fields, with the goal of achieving significant reductions in SV perpetration and allowing individuals to live to their full potential. PMID:23140201

Digital Intraoral Imaging Re-Exposure Rates of Dental Students.

PubMed

Senior, Anthea; Winand, Curtis; Ganatra, Seema; Lai, Hollis; Alsulfyani, Noura; Pachêco-Pereira, Camila

2018-01-01

A guiding principle of radiation safety is ensuring that radiation dosage is as low as possible while yielding the necessary diagnostic information. Intraoral images taken with conventional dental film have a higher re-exposure rate when taken by dental students compared to experienced staff. The aim of this study was to examine the prevalence of and reasons for re-exposure of digital intraoral images taken by third- and fourth-year dental students in a dental school clinic. At one dental school in Canada, the total number of intraoral images taken by third- and fourth-year dental students, re-exposures, and error descriptions were extracted from patient clinical records for an eight-month period (September 2015 to April 2016). The data were categorized to distinguish between digital images taken with solid-state sensors or photostimulable phosphor plates (PSP). The results showed that 9,397 intraoral images were made, and 1,064 required re-exposure. The most common error requiring re-exposure for bitewing images was an error in placement of the receptor too far mesially or distally (29% for sensors and 18% for PSP). The most common error requiring re-exposure for periapical images was inadequate capture of the periapical area (37% for sensors and 6% for PSP). A retake rate of 11% was calculated, and the common technique errors causing image deficiencies were identified. Educational intervention can now be specifically designed to reduce the retake rate and radiation dose for future patients.

Marine and Lacustrine Organic-rich Sedimentary Unit Time Markers: Implications from Rhenium-Osmium Geochronology

NASA Astrophysics Data System (ADS)

Selby, D.

2011-12-01

Geochronology is fundamental to understand the age, rates and durations of Earth processes. This concerned Arthur Holmes who, for much of his career, attempted to define a geological time scale. This is a topic still important to Earth Scientists today, specifically the chronostratigraphy of sedimentary rocks. Here I explore the Re-Os geochronology of marine and lacustrine sedimentary rocks and its application to yield absolute time constraints for stratigraphy. The past decade has seen the pioneering research of Re-Os organic-rich sedimentary rock geochronology blossom into a tool that can now to be used to accurately and precisely determine depositional ages of organic-rich rock units that have experienced up to low grade greenschist metamorphism. This direct dating of sedimentary rocks is critical where volcanic horizons are absent. As a result, this tool has been applied to timescale calibration, basin correlation, formation duration and the timing of key Earth events (e.g., Neoproterozoic glaciations). The application of Re-Os chronometer to the Devonian-Mississippian boundary contained within the Exshaw Formation, Canada, determined an age of 361.3 ± 2.4 Ma. This age is in accord with U-Pb dates of interbedded tuff horizons and also U-Pb zircon date for the type Devonian-Mississippian Hasselbachtal section, Germany. The agreement of the biostratigraphic and U-Pb constraints of the Exshaw Formation with the Re-Os date illustrated the potential of the Re-Os chronometer to yield age determinations for sedimentary packages, especially in the absence of interbedd tuff horizons and biozones. A Re-Os date for the proposed type section of the Oxfordian-Kimmeridgian boundary, Staffin Bay, Isle of Skye, U.K., gave an age of 154.1 ± 2.2 Ma. This Re-Os age presents a 45 % (1.8 Ma) improvement in precision for the basal Kimmeridgian. It also demonstrated that the duration of the Kimmeridgian is nominally 3.3 Ma and thus is 1.6 Ma shorter than previously indicated. In addition to these examples, several studies have presented precise dates for Phanerozoic marine organic-rich units that are in excellent agreement with biostratigraphic determinations. A recent Re-Os study of the Woodford Shale (that was deposited throughout the Frasnian and Famennian) has provided important time markers as well as suggesting that the sedimentation rate of the Formation was relatively constant for ~20 Ma. To date only marine organic-rich sedimentary rocks have been utilized for Re-Os geochronology. However, lacustrine sedimentary rocks provide an invaluable archive of continental geological processes responding to tectonic, climatic and magmatic influences. Correlating these rocks to global geological phenomena requires accurate geochronological frameworks. The organic-rich lacustrine sedimentary units of the Eocene Green River Formation are enriched is Re and Os comparable to that of marine units. The Re-Os dates for the Green River Formation from the Uinta basin are 48.5 ± 0.6 Ma and 49.2 ± 1.0 Ma. These dates are in excellent agreement with Ar/Ar and U/Pb dates of interbedded tuffs in the GRF, therefore demonstrating that lacustrine units can be used for Re-Os geochronology in addition to marine organic-rich units.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Speer, B.; Koenig, R.

Under property-assessed clean energy (PACE) and similar programs, municipal financing districts lend the proceeds of bonds to property owners for financing energy retrofits. Property owners who invest in energy efficiency (EE) measures and small renewable energy (RE) systems then repay these loans over 15-20 years via annual assessments on their property tax bills. States and local governments can use PACE bonds to help property owners finance EE and RE projects. This factsheet outlines the benefits of PACE programs and describes how they can be designed, implemented, and funded. The factsheet also summarizes the benefits and challenges experienced by PACE programsmore » in Boulder County, Colorado; Annapolis, Maryland; Berkeley, California; Sonoma County, California; Palm Desert, California; and Babylon, New York.« less

A Re-Os Study of Depleted Trench Peridotites from Northern Mariana

NASA Astrophysics Data System (ADS)

Ghosh, T.; Snow, J. E.; Heri, A. R.; Brandon, A. D.; Ishizuka, O.

2017-12-01

Trench peridotites provide information about the influence of subduction initiation on the extent of mantle wedge melting. They preserve melting records throughout subduction history, and as a result, likely experience multiple melt extraction events leading to successive depletion of melt/fluid mobile major and trace elements. To track melting histories of trench peridotites, Re-Os and PGEs can be used as reliable tracers to constrain early melt extraction or re-fertilization events. The Izu-Bonin-Mariana arc, being the largest intra-oceanic subduction system, provides an excellent area to study the formation of supra-subduction zone mantle and crust. Residual peridotite (harzburgite and dunite) samples were collected by dredging from the landward slope of the northern Mariana Trench. The samples are serpentinized to various extents (typical of abyssal peridotites), leaving behind relict grains of spinel, enstatite and olivine embedded within a serpentine matrix along with occasional interstitial diopside. Major element analyses of primary minerals reveal a wide range of variations in Cr# of spinels from 0.31-0.85 indicating 16-20% of melt fraction with dunites apparently experiencing the highest amount of partial melting. For Re-Os and PGE geochemistry, samples with high amounts of spinel (>4 vol %) and variable Cr# were chosen. Initial results show that bulk rock 187Os/188Os ratios range from 0.1113 to 0.1272. All of the samples are sub-chondritic, but in some cases, they are more radiogenic than average abyssal peridotites. Os abundances vary from 1-9 ppb. Sub-chondritic values can be attributed to the samples having evolved from a Re-depleted mantle source indicating a previous melt-extraction event. The cpx-harzburgites, having lower Cr# ( 0.4) are more radiogenic than ultra depleted dunites (Cr# 0.8), which might indicate preferential removal of Os during an apparent higher degree of partial melting experienced by dunites. The higher 187Os/188Os ratios of cpx-harzburgites possibly imply a late stage melt-rock interaction event, which had refertilized the depleted samples in radiogenic Os. Since there are only trace amounts of sediments in the accretionary prism of N. Mariana, Os ratios of these trench peridotites are not influenced by Os from sediments.

Minor long-term effects 3-4 years after the ReDO™ intervention for women with stress-related disorders: A focus on sick leave rate, everyday occupations and well-being.

PubMed

Eklund, Mona

2017-01-01

The Redesigning Daily Occupations (ReDO™) work rehabilitation method has been found effective, compared with care as usual (CAU), for women with stress-related disorders. To conduct a long-term follow-up of former ReDO™ and CAU participants with respect to sick leave, well-being and everyday occupations 3-4 years after completed work rehabilitation. Forty-two women in each group participated. An index day was decided to estimate sick-leave rate, retrieved from register data. Fifty-five women also participated in a telephone interview addressing well-being, everyday occupations and life events. Both groups had reduced their sick-leave rate further, but no difference between the groups was established. The ReDO™ women perceived a better balance in the work domain of everyday occupations, whereas the CAU group reported more over-occupation. No differences were found on well-being. The groups had experienced similar important life events, affecting the women's work and private lives. Previous stress and anxiety predicted sick leave at the long-term follow-up. Although the ReDO™ intervention had speeded up return to work in the immediate follow-up perspective, the CAU had caught up in the longer term. Still, the ReDO™ women exhibited better balance in the work domain.

Multisensory Origin of the Subjective First-Person Perspective: Visual, Tactile, and Vestibular Mechanisms

PubMed Central

Pfeiffer, Christian; Lopez, Christophe; Schmutz, Valentin; Duenas, Julio Angel; Martuzzi, Roberto; Blanke, Olaf

2013-01-01

In three experiments we investigated the effects of visuo-tactile and visuo-vestibular conflict about the direction of gravity on three aspects of bodily self-consciousness: self-identification, self-location, and the experienced direction of the first-person perspective. Robotic visuo-tactile stimulation was administered to 78 participants in three experiments. Additionally, we presented participants with a virtual body as seen from an elevated and downward-directed perspective while they were lying supine and were therefore receiving vestibular and postural cues about an upward-directed perspective. Under these conditions, we studied the effects of different degrees of visuo-vestibular conflict, repeated measurements during illusion induction, and the relationship to a classical measure of visuo-vestibular integration. Extending earlier findings on experimentally induced changes in bodily self-consciousness, we show that self-identification does not depend on the experienced direction of the first-person perspective, whereas self-location does. Changes in bodily self-consciousness depend on visual gravitational signals. Individual differences in the experienced direction of first-person perspective correlated with individual differences in visuo-vestibular integration. Our data reveal important contributions of visuo-vestibular gravitational cues to bodily self-consciousness. In particular we show that the experienced direction of the first-person perspective depends on the integration of visual, vestibular, and tactile signals, as well as on individual differences in idiosyncratic visuo-vestibular strategies. PMID:23630611

Summary and synthesis: past and future changes in the Alaskan Boreal Forest.

Treesearch

F. Stuart Chapin; David McGuire; Roger W. Ruess; Marilyn W. Walker; Richard D. Boone; Mary E. Edwards; Bruce P. Finney; Larry D. Hinzman; Jeremy B. Jones; Glenn P. Juday; Eric S. Kasischke; Knut Kielland; Andrea H. Lloyd; Mark W. Oswood; Chien-Lu Ping; Eric Rexstad; Vladimir E. Romanovsky; Joshua P. Schimel; Elena B. Sparrow; Bjartmar Sveinbjörnsson; David W. Valentine; Keith Van Cleve; David L. Verbyla; Leslie A. Viereck; Richard A. Werner; Tricia L. Wurtz; John Yarie

2006-01-01

Historically the boreal forest has experienced major changes, and it remains a highly dynamic biome today. During cold phases of Quaternary climate cycles, forests were virtually absent from Alaska, and since the postglacial re-establishment of forests ca 13,000 years ago, here have been periods of both relative stability and rapid change (Chapter 5). Today, the...

Expression of Re-Experiencing Symptoms in the Therapeutic Context: A Mixed-Method Analysis of Young Children Exposed to Intimate Partner Violence

ERIC Educational Resources Information Center

Miller-Graff, Laura E.; Galano, Maria; Graham-Bermann, Sandra A.

2016-01-01

Assessment, diagnosis and treatment of preschoolers with post-traumatic stress disorder (PTSD) is an understudied domain, and translational research assisting practitioners in the real-life identification of PTSD symptoms is critical. The current study examined therapists' behavioural notes of 56 children participating in a 10-session intervention…

The New Principal: Now You're Cooking

ERIC Educational Resources Information Center

Gomez, Frank; Van Zant, Steve

2006-01-01

In this article, the authors, two experienced principals from two separate districts and mentors for new principals, explain that being a great principal is much the same as being the host of a great dinner party. The following are a few insights and tips-for new principals that can help any host (or principal) find rewards that go far beyond the…

"Un-Learning and Re-Learning": The Experiences of Chinese Undergraduates in a First Year Management Class in New Zealand

ERIC Educational Resources Information Center

Guan, Xiaoyan; Jones, Glyndwr

2012-01-01

The growth of China's economy over the last two decades saw many Chinese students going overseas to study. Like many western countries, New Zealand benefited from increased international student enrolments, with Chinese students making up the largest proportion of the numbers. Many of these students experienced "culture shock" in their…

Criteria for phytoplasma 16Sr group/subgroup delineation and the need of a platform for proper registration of new groups and subgroups

USDA-ARS?s Scientific Manuscript database

As more phytoplasmas are discovered in emerging and re-emerging plant diseases worldwide, the scheme for classification of phytoplasmas into 16S rRNA gene RFLP (16Sr) groups and subgroups is experiencing an ongoing rapid expansion. Improper delineation or designation of new groups and subgroups can...

It's Not Academic, You're in the Army Now: Adjustment to the Army as a Comparative Context for Adjustment to University.

ERIC Educational Resources Information Center

Wintre, Maxine Gallander; Ben-Knaz, Revital

2000-01-01

Investigated the presumed efficacy of authoritative parenting in influencing adjustment during basic training to the Israeli army, a more authoritarian environment. Found that authoritatively reared children were at a disadvantage with regard to successful adjustment to the army. They were more depressed, experienced greater stress, and had lower…

"It's Just Because We're Girls": How Female Students Experience and Negotiate Masculinist School Sport

ERIC Educational Resources Information Center

McSharry, Majella

2017-01-01

This article focuses on the inequalities experienced particularly by girls who attend co-educational secondary schools where specific male sports dominate school life. The research was undertaken in the Republic of Ireland in three schools known for the participation and success of boys' teams in Gaelic football, hurling and rugby. Through a…

Psychological distress among re-education through labour camp detainees in Guangxi Autonomous Region, China.

PubMed

Yap, Lorraine; Shu, Su; Zhang, Lei; Liu, Wei; Chen, Yi; Wu, Zunyou; Li, Jianghong; Wand, Handan; Donovan, Basil; Butler, Tony

2017-02-01

There is currently no information about the prevalence of, and factors contributing to psychological distress experienced by re-education through labour camp detainees in China. A cross-sectional face-to-face survey was conducted in three labour camps in Guangxi, China. The questionnaire covered socio-demographic characteristics; sexually transmissible infections (STIs); drug use; psychological distress (K-10); and health service usage and access inside the labour camps. K-10 scores were categorised as ≤30 (low to moderate distress) and  >30 or more (highly distressed). Univariate and multivariate logistic regression models identified factors independently associated with high K-10 scores for men and women separately. In total, 755 detainees, 576 (76%) men and 179 (24%) women, participated in the health survey. The study found 11.6% men versus 11.2% women detainees experienced high psychological distress, but no significant gender differences were observed (p> 0.05). Multivariate logistic regression showed that multiple physical health problems were significantly associated with high psychological distress among men. Drug treatment and forensic mental health services need to be established in detention centres in China to treat more than 10% of detainees with drug use and mental health disorders.

Posttraumatic Stress Symptomatology in Pre-Hospital Emergency Care Professionals Assaulted by Patients and/or Relatives: Importance of Severity and Experience of the Aggression.

PubMed

Gómez-Gutiérrez, M Mar; Bernaldo-de-Quirós, Mónica; Piccini, Ana T; Cerdeira, Jose C

2016-01-01

Exposure to violence from patients or relatives causes problems in emergency departments. To assess the development of posttraumatic symptoms in pre-hospital emergency care professionals assaulted by patients and/or relatives, it may be crucial to establish preventive measures at different levels. This study examined 358 pre-hospital emergency care professionals assaulted by patients and/or relatives. The aims of the present study were (a) to assess the presence of posttraumatic symptoms and posttraumatic stress disorder (PTSD) and (b) identify compliance diagnoses for PTSD depending on the experience of aggression (presence of fear, helplessness, or horror during the aggression), the perceived severity of aggression, and socio-demographic variables (gender, age, profession, employment status, and work experience). The results show that the experience of aggression with fear, helplessness, or horror is associated with the presence of posttraumatic symptoms related to re-experiencing but is not related to avoidance and emotional numbing and arousal. Furthermore, the perception of aggression as severe was associated with the presence of symptoms related to re-experiencing. These results are presented and discussed. © The Author(s) 2014.

'Pre-Run, Re-Run': An innovative research capacity building exercise.

PubMed

McAllister, Margaret; Brien, Donna Lee

2017-11-01

Within higher education it is ironic that experienced and novice researchers rarely take the opportunity to come together to share their research - whether these be to discuss findings, puzzles or developing projects. Within this paper, an innovative strategy building on these assumptions is described. It is entitled: 'Pre-run, Re-run' and is a learning community where specific processes are modelled by all to help build professional communication, collegial respect, and scholarship. Our evaluation showed that there is value in bringing together researchers especially when they have diverse profiles. Also, mixing experience with naivety, by inviting professors and junior staff to fraternize equally, offers the possibility for wide ranging discussion, as well as sharing a range of successful techniques, knowledge of the big picture and ways around obstacles that would otherwise be off-putting for novices. The less experienced perspective can equally be revitalizing because newcomers to scholarship often bring a fresh focus and enthusiasm and energy for practice. While this was a local innovation, which may not be generalizable to all settings, others hoping to bring together disciplines may benefit from utilizing the successful methods to build a productive, mixed research culture. Copyright © 2017 Elsevier Ltd. All rights reserved.

Unprecedented linking of two polyoxometalate units with a metal-metal multiple bond.

PubMed

Sokolov, Maxim N; Korenev, Vladimir S; Izarova, Natalya V; Peresypkina, Eugenia V; Vicent, Cristian; Fedin, Vladimir P

2009-03-02

The reaction of (Bu(4)N)(2)[Re(2)Cl(8)] with lacunary Keggin polyoxometalate K(7)[PW(11)O(39)] in water produces a new dumbbell-shaped heteropolyoxometalate anion, [Re(2)(PW(11)O(39))(2)](8-), whose structure contains a central Re(2) core with a quadruple bond between Re atoms (Re-Re 2.25 A), coordinated to two polyoxometalate units. This complex represents the first example of the direct linking of two polyoxometalate units via a metal-metal multiple bond. The compounds were characterized by X-ray analysis, IR, and electrospray ionization mass spectrometry.

Victimization experiences and adolescent substance use: does the type and degree of victimization matter?

PubMed

Pinchevsky, Gillian M; Fagan, Abigail A; Wright, Emily M

2014-01-01

Evidence indicates an association between victimization and adolescent substance use, but the exact nature of this relationship remains unclear. Some research focuses solely on the consequences of experiencing indirect victimization (e.g., witnessing violence), others examine direct victimization (e.g., being personally victimized), and still others combine both forms of victimization without assessing the relative impact of each on substance use. Furthermore, many of these studies only assess these relationships in the short-term using cross-sectional data. This study uses data from the Project on Human Development in Chicago Neighborhoods (PHDCN) to explore the impact of experiencing only indirect victimization, only direct victimization, both forms of victimization, and no victimization on substance use at two time points during adolescence. We find that of those adolescents who are victimized, the majority experience indirect victimization only, followed by experiencing both forms of victimization, and experiencing direct victimization only. Each of the victimization experiences were associated with increased contemporaneous substance use, with the strongest effects for those experiencing multiple forms of violence. For all victims, however, the impact on substance use declined over time.

Victimization Experiences and Adolescent Substance Use: Does the Type and Degree of Victimization Matter?

PubMed Central

Pinchevsky, Gillian M.; Fagan, Abigail A.; Wright, Emily M.

2014-01-01

Evidence indicates an association between victimization and adolescent substance use, but the exact nature of this relationship remains unclear. Some research focuses solely on the consequences of experiencing indirect victimization (e.g., witnessing violence), others examine direct victimization (e.g., being personally victimized), and still others combine both forms of victimization without assessing the relative impact of each on substance use. Furthermore, many of these studies only assess these relationships in the short-term using cross-sectional data. This study uses data from the Project on Human Development in Chicago Neighborhoods (PHDCN) to explore the impact of experiencing only indirect victimization, only direct victimization, both forms of victimization, and no victimization on substance use at two time points during adolescence. We find that of those adolescents who are victimized, the majority experience indirect victimization only, followed by experiencing both forms of victimization, and experiencing direct victimization only. Each of the victimization experiences were associated with increased contemporaneous substance use, with the strongest effects for those experiencing multiple forms of violence. For all victims, however, the impact on substance use declined over time. PMID:24144722

Prioritization methodology for chemical replacement

NASA Technical Reports Server (NTRS)

Goldberg, Ben; Cruit, Wendy; Schutzenhofer, Scott

1995-01-01

This methodology serves to define a system for effective prioritization of efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi quantitative approach derived from quality function deployment techniques (QFD Matrix). QFD is a conceptual map that provides a method of transforming customer wants and needs into quantitative engineering terms. This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives.

'Emerging technologies for the changing global market' - Prioritization methodology for chemical replacement

NASA Technical Reports Server (NTRS)

Cruit, Wendy; Schutzenhofer, Scott; Goldberg, Ben; Everhart, Kurt

1993-01-01

This project served to define an appropriate methodology for effective prioritization of technology efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semiquantitative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results will be implemented as a guideline for consideration for current NASA propulsion systems.

Emerging technologies for the changing global market

NASA Technical Reports Server (NTRS)

Cruit, Wendy; Schutzenhofer, Scott; Goldberg, Ben; Everhart, Kurt

1993-01-01

This project served to define an appropriate methodology for effective prioritization of technology efforts required to develop replacement technologies mandated by imposed and forecast legislation. The methodology used is a semi-quantative approach derived from quality function deployment techniques (QFD Matrix). This methodology aims to weight the full environmental, cost, safety, reliability, and programmatic implications of replacement technology development to allow appropriate identification of viable candidates and programmatic alternatives. The results will be implemented as a guideline for consideration for current NASA propulsion systems.

Binary Asteroids and Human Exploration Considerations

NASA Technical Reports Server (NTRS)

Abell, P. A.

2013-01-01

In 2009 the Augustine Commission identified near-Earth asteroids (NEAs) as high profile destinations for human exploration missions beyond the Earth-Moon system as part of the Flexible Path. Subsequently, the U.S. presidential administration directed NASA on April 15, 2010 to include NEAs as destinations for future human exploration with the goal of sending astronauts to a NEA in the mid to late 2020s. This directive became part of the official National Space Policy of the United States of America as of June 28, 2010. Current NASA plans to explore NEAs do not include binary systems. However, with a few in situ robotic precursor missions to binary NEAs, and increased confidence in human mission capabilities, the scientific and hazard mitigation benefits, along with the programmatic and operational benefits of a human venture beyond the Earth-Moon system, make a mission to a binary NEA using NASA's proposed exploration systems a compelling endeavor.

Empowering adolescent girls in Sub-Saharan Africa to prevent unintended pregnancy and HIV: A critical research gap.

PubMed

Phillips, Sharon J; Mbizvo, Michael T

2016-01-01

The need to prevent early pregnancy and HIV among adolescent girls in Sub-Saharan Africa has been recognized increasingly over recent years. Although extensive work has been done to determine appropriate interventions for girls in high-income countries, very little evidence is available to guide programmatic interventions in Sub-Saharan Africa. The available evidence has been equivocal regarding improved outcomes. While knowledge and self-reported behaviors frequently change with interventions, including those performed at the community level, educational programs, and direct contraceptive provision, downstream outcomes rarely reflect a significant effect of the interventions; however, provision of financial or other interventions to incentivize continued school enrollment are a promising development. We suggest directions for future research to fill this critical gap in the literature. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Temperature threshold of isoprene emission from tropical trees, Ficus virgata and Ficus septica.

PubMed

Oku, Hirosuke; Inafuku, Masashi; Takamine, Tomonori; Nagamine, Maki; Saitoh, Seikoh; Fukuta, Masakazu

2014-01-01

This paper describes the existence of temperature threshold in isoprene emission from tropical trees for the first time. Isoprene emission capacity of Ficus virgata leaves kept outdoors were measured over a period of 20 d in the wintertime. When the plants experienced the low temperature below 12 °C in the daytime, isoprene emission was completely suppressed, and re-activated by elevated temperature above the threshold of 12 °C. Photosynthesis is also decreased similarly, but too much smaller extent compared to the reduction observed for isoprene emission. The cut off level of accumulated temperature to shut off the isoprene emission was roughly estimated to be 300 degree/d. The shut off in the isoprene emission by the low temperature was confirmed experimentally by use of phytotron with tropical trees of F. virgata and F. septica. Isoprene emission of both species ceased at 12 °C, and re-activated by raising the temperature above the threshold level. Photosynthesis was lowered slightly as was the case for the field observation, and no close association between photosynthesis and isoprene emission was noted. The expression of isoprene synthase gene showed much greater variation after exposure to the cold temperature compared to those involved in photosynthesis. These observations therefore suggested the existence of putative direct connection between perception of temperature and isoprene emission in tropical trees, which may merit further investigation to estimate the net output of isoprene from subtropical or tropical forest. Copyright © 2013 Elsevier Ltd. All rights reserved.

Safety of Radioembolization with {sup 90}Yttrium Resin Microspheres Depending on Coiling or No-Coiling of Aberrant/High-Risk Vessels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paprottka, P. M., E-mail: philipp.paprottka@med.lmu.de, E-mail: philipp.paprottka@med.uni-muenchen.de; Paprottka, K. J., E-mail: karolin.paprottka@med.lmu.de; Walter, A., E-mail: alexandra.Walter@campus.lmu.de

2015-08-15

PurposeTo evaluate the safety of radioembolization (RE) with {sup 90}Yttrium ({sup 90}Y) resin microspheres depending on coiling or no-coiling of aberrant/high-risk vessels.Materials and MethodsEarly and late toxicity after 566 RE procedures were analyzed retrospectively in accordance with the National Cancer Institute’s Common Terminology Criteria for Adverse Events (CTCAE v3.0). For optimal safety, aberrant vessels were either coil embolized (n = 240/566, coiling group) or a more peripheral position of the catheter tip was chosen to treat right or left liver lobes (n = 326/566, no-coiling group).ResultsClinically relevant late toxicities (≥Grade 3) were observed in 1 % of our overall cohort. The no-coiling group had significantlymore » less “any” (P = 0.0001) or “clinically relevant” (P = 0.0003) early toxicity. There was no significant difference (P > 0.05) in delayed toxicity in the coiling versus the no-coiling group. No RE-induced liver disease was noted after all 566 procedures.ConclusionRE with {sup 90}Y resin microspheres is a safe and effective treatment option. Performing RE without coil embolization of aberrant vessels prior to treatment could be an alternative for experienced centers.« less

Consumer Directed Care in Australia: early perceptions and experiences of staff, clients and carers.

PubMed

Gill, Liz; McCaffrey, Nikki; Cameron, Ian D; Ratcliffe, Julie; Kaambwa, Billingsley; Corlis, Megan; Fiebig, Jeff; Gresham, Meredith

2017-03-01

The study aimed to identify the shared issues and challenges being experienced by staff, their clients and informal carers, with the introduction of Consumer Directed Care (CDC). Secondary analysis was undertaken of data that had been initially collected, via semi-structured in-depth interviews, to inform the development of a discrete choice experiment. The raw staff and client/carer data were re-examined using an iterative inductive process. The analysis focused on locating the shared themes and differences between the participant groups based on their CDC experience. The data were also assessed for difficulties or barriers that impacted on the service. Four broad shared themes were derived: culture, role change, operational systems and resourcing, but with a range of diverse and sometimes conflicting sub-themes between the different participant groups. Differences can be linked to participant role in the service chain, with discordance emerging between what has been traditionally offered and what might be possible. This investigation occurred during the period in which services were transitioning from a traditional aged care service model to a new model of service provision requiring considerable industry change. We conclude that existing industry regulation, culture and practice supports an established service model in Australia that arguably makes translation of the objectives of CDC difficult. © 2016 John Wiley & Sons Ltd.

Cortisol, learning, memory, and attention in relation to smaller hippocampal volume in police officers with posttraumatic stress disorder.

PubMed

Lindauer, Ramón J L; Olff, Miranda; van Meijel, Els P M; Carlier, Ingrid V E; Gersons, Berthold P R

2006-01-15

A proposed explanation for memory impairments in posttraumatic stress disorder (PTSD) is stress-induced hippocampal damage due to elevated cortisol levels. We have previously reported smaller hippocampi in police officers with PTSD. In this study, we examined changes in and associations between cortisol, learning, memory, attention, and hippocampal volume in PTSD. In a case-matched control study, 12 police officers with PTSD and 12 traumatized police officers without lifetime PTSD were examined with magnetic resonance imaging (for hippocampal volume), salivary cortisol tests, and neurocognitive assessments. Significantly smaller hippocampi and higher early morning salivary cortisol levels were found in PTSD. Subjects with PTSD performed worse on a delayed visual memory recall task at trend level, and made more perseverations and intrusions on a verbal memory task. Negative correlations were found between PTSD symptom severity and immediate recall function, and between re-experiencing symptoms and left hippocampal volume. A positive correlation was found between salivary cortisol level in early morning and right hippocampal volume; however, hippocampal volume did not correlate with memory. Smaller hippocampi, higher cortisol levels, and memory impairments were associated with PTSD but were not directly correlated to one another. Memory impairments in PTSD do not seem to be a direct consequence of hippocampal size.

The work and recovery project: changing organizational culture and practice in New York City outpatient services.

PubMed

Pascaris, Alysia; Shields, Leslie Reed; Wolf, Jessica

2008-01-01

Complex and multiple barriers confront out-patient programs in promoting recovery and addressing mental health recipients' work-related goals. This article describes a focused organizational change project utilizing intensive consultation and technical assistance within five New York City outpatient psychiatric services. The project aimed to increase staff exposure to, understanding and use of work-related and recovery-based concepts to promote consumers' recovery and attainment of employment goals. Tailored assessment, curriculum delivery, and identification and implementation of change objectives were useful strategies in promoting change. This change model can serve to assist programs in their efforts to integrate new approaches and to better understand changes among leadership, staff and consumers, and changes in organizational culture and practice required to support a work and recovery-oriented service paradigm. The project experience suggests that adopting and embracing new practices takes time. Varied and incremental steps toward programmatic and operational changes can be significant and can reap authentic sustainable change occurring in the process of learning, experiencing, internalizing and adjusting to new methods of practice.

Prevention, control, and elimination of neglected diseases in the Americas: Pathways to integrated, inter-programmatic, inter-sectoral action for health and development

PubMed Central

Holveck, John C; Ehrenberg, John P; Ault, Steven K; Rojas, Rocio; Vasquez, Javier; Cerqueira, Maria Teresa; Ippolito-Shepherd, Josefa; Genovese, Miguel A; Periago, Mirta Roses

2007-01-01

Background In the Latin America and Caribbean region over 210 million people live below the poverty line. These impoverished and marginalized populations are heavily burdened with neglected communicable diseases. These diseases continue to enact a toll, not only on families and communities, but on the economically constrained countries themselves. Discussion As national public health priorities, neglected communicable diseases typically maintain a low profile and are often left out when public health agendas are formulated. While many of the neglected diseases do not directly cause high rates of mortality, they contribute to an enormous rate of morbidity and a drastic reduction in income for the most poverty-stricken families and communities. The persistence of this "vicious cycle" between poverty and poor health demonstrates the importance of linking the activities of the health sector with those of other sectors such as education, housing, water and sanitation, labor, public works, transportation, agriculture, industry, and economic development. Summary The purpose of this paper is three fold. First, it focuses on a need for integrated "pro-poor" approaches and policies to be developed in order to more adequately address the multi-faceted nature of neglected diseases. This represents a move away from traditional disease-centered approaches to a holistic approach that looks at the overarching causes and mechanisms that influence the health and well being of communities. The second objective of the paper outlines the need for a specific strategy for addressing these diseases and offers several programmatic entry points in the context of broad public health measures involving multiple sectors. Finally, the paper presents several current Pan American Health Organization and other institutional initiatives that already document the importance of integrated, inter-programmatic, and inter-sectoral approaches. They provide the framework for a renewed effort toward the efficient use of resources and the development of a comprehensive integrated solution to neglected communicable diseases found in the context of poverty, and tailored to the needs of local communities. PMID:17229324

Three-dimensional beam pattern of regular sperm whale clicks confirms bent-horn hypothesis

NASA Astrophysics Data System (ADS)

Zimmer, Walter M. X.; Tyack, Peter L.; Johnson, Mark P.; Madsen, Peter T.

2005-03-01

The three-dimensional beam pattern of a sperm whale (Physeter macrocephalus) tagged in the Ligurian Sea was derived using data on regular clicks from the tag and from hydrophones towed behind a ship circling the tagged whale. The tag defined the orientation of the whale, while sightings and beamformer data were used to locate the whale with respect to the ship. The existence of a narrow, forward-directed P1 beam with source levels exceeding 210 dBpeak re: 1 μPa at 1 m is confirmed. A modeled forward-beam pattern, that matches clicks >20° off-axis, predicts a directivity index of 26.7 dB and source levels of up to 229 dBpeak re: 1 μPa at 1 m. A broader backward-directed beam is produced by the P0 pulse with source levels near 200 dBpeak re: 1 μPa at 1 m and a directivity index of 7.4 dB. A low-frequency component with source levels near 190 dBpeak re: 1 μPa at 1 m is generated at the onset of the P0 pulse by air resonance. The results support the bent-horn model of sound production in sperm whales. While the sperm whale nose appears primarily adapted to produce an intense forward-directed sonar signal, less-directional click components convey information to conspecifics, and give rise to echoes from the seafloor and the surface, which may be useful for orientation during dives..

The Use of Re-irradiation in Locally Recurrent, Non-metastatic Rectal Cancer.

PubMed

Susko, Matthew; Lee, Jason; Salama, Joseph; Thomas, Samantha; Uronis, Hope; Hsu, David; Migaly, John; Willett, Christopher; Czito, Brian; Palta, Manisha

2016-10-01

The optimal approach to patients with locally recurrent, non-metastatic rectal cancer is unclear. This study evaluates the outcomes and toxicity associated with pelvic re-irradiation. Patients undergoing re-irradiation for locally recurrent, non-metastatic, rectal cancer between 2000 and 2014 were identified. Acute and late toxicities were assessed using common terminology criteria for adverse events version 4.0. Disease-related endpoints included palliation of local symptoms, surgical outcomes, and local progression-free survival (PFS), distant PFS and overall survival (OS) using the Kaplan-Meier method. Thirty-three patients met the criteria for inclusion in this study. Two (6 %) experienced early grade 3+ toxicity and seven (21 %) experienced late grade 3+ toxicity. Twenty-three patients presented with symptomatic local recurrence and 18 (78 %) reported symptomatic relief. Median local PFS was 8.7 (95 % CI 3.8-15.2) months, with a 2-year rate of 15.7 % (4.1-34.2), and median time to distant progression was 4.4 (2.2-33.3) months, with a 2-year distant PFS rate of 38.9 % (20.1-57.3). Median OS time for patients was 23.1 (11.1-33.0) months. Of the 14 patients who underwent surgery, median survival was 32.3 (13.8-48.0) months compared with 13.3 (2.2-33.0) months in patients not undergoing surgery (p = 0.10). A margin-negative (R0) resection was achieved in 10 (71 %) of the surgeries. Radiation treatment modality (intensity-modulated radiation therapy, three-dimensional conformal radiotherapy, intraoperative radiation therapy) did not influence local or distant PFS or OS. Re-irradiation is a beneficial treatment modality for the management of locally recurrent, non-metastatic rectal cancer. It is associated with symptom improvement, low rates of toxicity, and similar benefits among radiation modalities.

Comparison of three different dressings for partial thickness burns in children: study protocol for a randomised controlled trial

PubMed Central

2013-01-01

Background In the paediatric population, pain and distress associated with burn injuries during wound care procedures remain a constant challenge. Although silver dressings are the gold standard for burn care in Australasia, very few high-level trials have been conducted that compare silver dressings to determine which will provide the best level of care clinically. Therefore, for paediatric patients in particular, identifying silver dressings that are associated with lower levels of pain and rapid wound re-epithelialisation is imperative. This study will determine whether there is a difference in time to re-epithelialisation and pain and distress experienced during wound care procedures among Acticoat™, Acticoat™ combined with Mepitel™ and Mepilex Ag™ dressings for acute, paediatric partial thickness burns. Methods/Design Children aged 0 to 15 years with an acute partial thickness (superficial partial to deep partial thickness inclusive) burn injury and a burn total body surface area of ≤10% will be eligible for the trial. Patients will be randomised to one of the three dressing groups: (1) Acticoat™ or (2) Acticoat™ combined with Mepitel™ or (3) Mepilex Ag™. A minimum of 28 participants will be recruited for each treatment group. Primary measures of pain, distress and healing will be repeated at each dressing change until complete wound re-epithelialisation occurs or skin grafting is required. Additional data collected will include infection status at each dressing change, physical function, scar outcome and scar management requirements, cost effectiveness of each dressing and staff perspectives of the dressings. Discussion The results of this study will determine the effects of three commonly used silver and silicone burn dressing combinations on the rate of wound re-epithelialisation and pain experienced during dressing procedures in acute, paediatric partial thickness burn injuries. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12613000105741 PMID:24274190

Re-exposure to low osmolar iodinated contrast media in patients with prior moderate-to-severe hypersensitivity reactions: A multicentre retrospective cohort study.

PubMed

Park, Hye Jung; Park, Jung-Won; Yang, Min-Suk; Kim, Mi-Yeong; Kim, Sae-Hoon; Jang, Gwang Cheon; Nam, Young-Hee; Kim, Gun-Woo; Kim, Sujeong; Park, Hye-Kyung; Jung, Jae-Woo; Park, Jong-Sook; Kang, Hye-Ryun

2017-07-01

To evaluate the outcomes of re-exposure to low-osmolar iodinated contrast medium (LOCM) in patients with a history of moderate-to-severe hypersensitivity reaction (HSR). We retrospectively evaluated a cohort comprising all subjects satisfying the following conditions at 11 centres: (1) experienced a moderate-to-severe HSR to LOCM by December 2014, and (2) underwent contrast-enhanced computed tomography after the initial HSR between January 2014 and December 2014. A total of 150 patients with 328 instances of re-exposure were included; the recurrence rate of HSR was 19.5%. Patients with severe initial HSR exhibited a higher recurrence rate of severe HSR compared to patients with moderate initial HSR, despite more intensive premedication. In the multivariate analysis, the independent risk factors for recurrence of HSR were diabetes, chronic urticaria, drug allergy other than to iodinated contrast media (ICM) and severe initial HSR. The risk of recurrent HSR was 67.1% lower in cases where the implicated ICM was changed to another one (odds ratio: 0.329; P = 0.001). However, steroid premedication did not show protective effects against recurrent HSR. In high-risk patients who have previously experienced a moderate-to-severe initial HSR to LOCM, we should consider changing the implicated ICM to reduce recurrence risk. • In patients with moderate-to-severe HSR, steroid premedication only shows limited effectiveness. • Changing the implicated ICM can reduce the recurrence of HSR to ICM. • Diabetes, chronic urticaria and drug allergies increase the risk of ICM HSR.