Science.gov

Sample records for experiments present status

  1. The Majorana Double Beta Decay Experiment: Present Status

    SciTech Connect

    Aguayo, Estanislao; Avignone, Frank T.; Back, Henning O.; Barabash, Alexander S.; Beene, Jim; Bergevin, M.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Chan, Yuen-Dat; Christofferson, C. D.; Collar, J. I.; Combs, Dustin C.; Cooper, R. J.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Esterline, James H.; Fast, James E.; Fields, N.; Finnerty, P.; Fraenkle, Florian; Gehman, Victor M.; Giovanetti, G. K.; Green, M. P.; Guiseppe, V. E.; Gusey, K.; Hallin, A. L.; Hazama, R.; Henning, Reyco; Hime, Andrew; Hoppe, Eric W.; Horton, Mark; Howard, Stanley; Howe, M. A.; Johnson, R. A.; Keeter, K.; Keller, C.; Kidd, M. F.; Knecht, A.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; Laferriere, Brian D.; LaRoque, B. H.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, S.; Marino, Michael G.; Martin, R. D.; Mei, Dong-Ming; Merriman, Jason H.; Miller, M. L.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; Overman, Nicole R.; Phillips II, D. G.; Poon, Alan; Perumpilly, Gopakumar; Prior, Gersende; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Ronquest, M. C.; Schubert, Alexis G.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Steele, David; Strain, J.; Thomas, K.; Timkin, V.; Tornow, W.; Vanyushin, I.; Varner, R. L.; Vetter, Kai; Vorren, Kris R.; Wilkerson, J. F.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir; Zhang, C.

    2013-06-01

    The Majorana collaboration is actively pursuing research and development aimed at a tonne-scale 76Ge neutrinoless double-beta decay experiment, an R&D effort that will field approximately 40 kg of germanium detectors with mixed enrichment levels. This article provides a status update on the construction of the Demonstrator

  2. Present status of the MISTRAL mass measurement experiment

    SciTech Connect

    Monsanglant, C.; Audi, G.; Doubre, H.; Duma, M.; Jacotin, M.; Kepinski, J.-F.; Le Scornet, G.; Saint Simon, M. de; Thibault, C.; Borcea, C.; Lebee, G.; Lunney, M. D.; Toader, C.

    1998-10-26

    The MISTRAL experiment for measuring masses of very short-lived nuclides at ISOLDE has been installed during the summer of 1997 and has had its first radioactive beam in November 1997. Tests are presently been carried out to study all possible systematic effects. This paper recalls the basic principles of the Smith-type radio-frequency spectrometer, gives its present characteristics and limitations, and describes the methods used to improve its performances.

  3. Present Status and Future Perspectives of the NEXT Experiment

    DOE PAGESBeta

    Gómez Cadenas, J. J.; Álvarez, V.; Borges, F. I. G.; Cárcel, S.; Castel, J.; Cebrián, S.; Cervera, A.; Conde, C. A. N.; Dafni, T.; Dias, T. H. V. T.; et al

    2014-01-01

    NEXT is an experiment dedicated to neutrinoless double beta decay searches in xenon. The detector is a TPC, holding 100 kg of high-pressure xenon enriched in the136Xe isotope. It is under construction in the Laboratorio Subterráneo de Canfranc in Spain, and it will begin operations in 2015. The NEXT detector concept provides an energy resolutionbetter than 1% FWHM and a topological signal that can be used to reduce the background. Furthermore, the NEXT technology can be extrapolated to a 1 ton-scale experiment.

  4. Present Status of Venusvenus

    NASA Astrophysics Data System (ADS)

    Sugimoto, Shojiro

    The TRISTAN e+e- collider came into operation in the last October. The first beam collision was confirmed with the VENUS detector on November 19, '86. Then we have observed 56 Bhabha events and 16 hadronic events for the integrated luminosity of 93 nb-1 at √ {s} = 50 GeV. R-value obtained by a preliminary quick analysis is 5.7±1.6. Here we report the present status and the results of the VENUS experiment.

  5. Indian aerosols: present status.

    PubMed

    Mitra, A P; Sharma, C

    2002-12-01

    This article presents the status of aerosols in India based on the research activities undertaken during last few decades in this region. Programs, like International Geophysical Year (IGY), Monsoon Experiment (MONEX), Indian Middle Atmospheric Program (IMAP) and recently conducted Indian Ocean Experiment (INDOEX), have thrown new lights on the role of aerosols in global change. INDOEX has proved that the effects of aerosols are no longer confined to the local levels but extend at regional as well as global scales due to occurrence of long range transportation of aerosols from source regions along with wind trajectories. The loading of aerosols in the atmosphere is on rising due to energy intensive activities for developmental processes and other anthropogenic activities. One of the significant observation of INDOEX is the presence of high concentrations of carbonaceous aerosols in the near persistent winter time haze layer over tropical Indian Ocean which have probably been emitted from the burning of fossil-fuels and biofuels in the source region. These have significant bearing on the radiative forcing in the region and, therefore, have potential to alter monsoon and hydrological cycles. In general, the SPM concentrations have been found to be on higher sides in ambient atmosphere in many Indian cities but the NOx concentrations have been found to be on lower side. Even in the haze layer over Indian Ocean and surrounding areas, the NOx concentrations have been reported to be low which is not conducive of O3 formation in the haze/smog layer. The acid rain problem does not seem to exist at the moment in India because of the presence of neutralizing soil dust in the atmosphere. But the high particulate concentrations in most of the cities' atmosphere in India are of concern as it can cause deteriorated health conditions. PMID:12492171

  6. Indian aerosols: present status.

    PubMed

    Mitra, A P; Sharma, C

    2002-12-01

    This article presents the status of aerosols in India based on the research activities undertaken during last few decades in this region. Programs, like International Geophysical Year (IGY), Monsoon Experiment (MONEX), Indian Middle Atmospheric Program (IMAP) and recently conducted Indian Ocean Experiment (INDOEX), have thrown new lights on the role of aerosols in global change. INDOEX has proved that the effects of aerosols are no longer confined to the local levels but extend at regional as well as global scales due to occurrence of long range transportation of aerosols from source regions along with wind trajectories. The loading of aerosols in the atmosphere is on rising due to energy intensive activities for developmental processes and other anthropogenic activities. One of the significant observation of INDOEX is the presence of high concentrations of carbonaceous aerosols in the near persistent winter time haze layer over tropical Indian Ocean which have probably been emitted from the burning of fossil-fuels and biofuels in the source region. These have significant bearing on the radiative forcing in the region and, therefore, have potential to alter monsoon and hydrological cycles. In general, the SPM concentrations have been found to be on higher sides in ambient atmosphere in many Indian cities but the NOx concentrations have been found to be on lower side. Even in the haze layer over Indian Ocean and surrounding areas, the NOx concentrations have been reported to be low which is not conducive of O3 formation in the haze/smog layer. The acid rain problem does not seem to exist at the moment in India because of the presence of neutralizing soil dust in the atmosphere. But the high particulate concentrations in most of the cities' atmosphere in India are of concern as it can cause deteriorated health conditions.

  7. Unimolecular rectifiers: Present status

    NASA Astrophysics Data System (ADS)

    Metzger, Robert M.

    2006-07-01

    Many experimental issues presented here must be resolved before we can really understand unimolecular rectification. Nevertheless, at the University of Alabama six unimolecular rectifiers have been studied (Fig. 1, 1- 6). Langmuir-Blodgett (LB) or Langmuir-Schaefer (LS) monolayer films of these molecules show asymmetric electrical conductivity between Au and Al electrodes. When the films are very compact (LS of 4, LB of 5), and if there is finite intramolecular charge transfer (ICT, or intervalence transfer, IVT), then the electrical behavior persists for many cycles of measurement.

  8. RTNS-II: present status

    SciTech Connect

    Heikkinen, D.W.; Logan, C.M.

    1980-10-01

    The present status of the RTNS-II facility is described and typical operating parameters are given. A brief discussion is given of the methods used in production of the TiT/sub 2/ targets as well as their performance and tritium handling at RTNS-II. The various types of non-interactive beam diagnostics presently in use at the neutron sources are outlined. The on-line computer system which provides a time history of an irradiation and records target performance is described. Examples are listed of several representative experimental programs which have been carried out thus far at RTNS-II. These include both active and passive experiments. Finally, several of the major improvements to the facility made since the beginning of the experimental program are given.

  9. Status of solar neutrino experiments

    SciTech Connect

    Beier, E.W.; Davis, R. Jr.; Kim, S.B. . Dept. of Physics); Elliott, S.R. ); Jelley, N. )

    1990-01-01

    A summary of the status of four solar neutrino experiments is presented. The Homestake {sup 37}Cl data are presented and the possible time dependence of the data is addressed. Data from 1040 days of operation of the Kamiokande II detector are presented next. The status of the {sup 71}Ga experiment in the Baksan Neutrino Observatory, which has operated for a short time, is discussed. The summary concludes with a discussion of the status of the Sudbury Neutrino Observatory, which has been under construction since the beginning of 1990. 7 refs., 6 figs.

  10. Schedule and status of irradiation experiments

    SciTech Connect

    Rowcliffe, A.F.; Grossbeck, M.L.

    1997-04-01

    To provide an updated summary of the status of irradiation experiments for the neutron-interactive materials program. The current status of reactor irradiation experiments is presented in tables summarizing the experimental objectives, conditions, and schedule. Currently, the program has two irradiation experiments in reactor; and 8 experiments in the planning or design stages. Postirradiation examination and testing is in progress on 18 experiments.

  11. Status of RENO Experiment

    NASA Astrophysics Data System (ADS)

    Jang, Jee-Seung

    2011-10-01

    The RENO (Reactor Experiment for Neutrino Oscillation) experiment is under construction to measure the smallest neutrino mixing angle θ13 using anti-neutrinos emitted from the Yonggwang nuclear power plant in Korea. The experiment is planning to start data-taking in early 2011 with two identical 16-ton Gadolinium loaded liquid scintillator detectors located near and far from the center of the reactor array. The estimated systematic uncertainty associated with the measurement is less than 0.6%. Based on three years of data, the expected statistical error is about 0.3% and it would be sensitive to measure the neutrino mixing angle in the range, sin2(2θ13)> 0.02. In this talk, the overview and status of RENO experiment are described.

  12. MOON for a next-generation neutrino-less double-beta decay experiment: Present status and perspective

    SciTech Connect

    Shima, T.; Doe, P.J.; Ejiri, H.; Elliot, S.R.; Engel, J.; Finger, M.; Finger, M.; Fushimi, K.; Gehman, V.M.; Greenfield, M.B.; Hazama, R.; /Hiroshima U. /NIRS, Chiba

    2008-01-01

    The performance of the MOON detector for a next-generation neutrino-less double-beta decay experiment was evaluated by means of the Monte Carlo method. The MOON detector was found to be a feasible solution for the future experiment to search for the Majorana neutrino mass in the range of 100-30 meV.

  13. Present status of aircraft instruments

    NASA Technical Reports Server (NTRS)

    1932-01-01

    This report gives a brief description of the present state of development and of the performance characteristics of instruments included in the following group: speed instruments, altitude instruments, navigation instruments, power-plant instruments, oxygen instruments, instruments for aerial photography, fog-flying instruments, general problems, summary of instrument and research problems. The items considered under performance include sensitivity, scale errors, effects of temperature and pressure, effects of acceleration and vibration, time lag, damping, leaks, elastic defects, and friction.

  14. Experiment SPHERE status 2008

    NASA Astrophysics Data System (ADS)

    Shaulov, S. B.; Besshapov, S. P.; Kabanova, N. V.; Sysoeva, T. I.; Antonov, R. A.; Anyuhina, A. M.; Bronvech, E. A.; Chernov, D. V.; Galkin, V. I.; Tkaczyk, W.; Finger, M.; Sonsky, M.

    2009-12-01

    The expedition carried out in March, 2008 to Lake Baikal became an important stage in the development of the SPHERE experiment. During the expedition the SPHERE-2 installation was hoisted, for the first time, on a tethered balloon, APA, to a height of 700 m over the lake surface covered with ice and snow. A series of test measurements were made. Preliminary results of the data processing are presented. The next plan of the SPHERE experiment is to begin a set of statistics for constructing the CR spectrum in the energy range 10-10 eV.

  15. Big bang nucleosynthesis: Present status

    NASA Astrophysics Data System (ADS)

    Cyburt, Richard H.; Fields, Brian D.; Olive, Keith A.; Yeh, Tsung-Han

    2016-01-01

    Big bang nucleosynthesis (BBN) describes the production of the lightest nuclides via a dynamic interplay among the four fundamental forces during the first seconds of cosmic time. A brief overview of the essentials of this physics is given, and new calculations presented of light-element abundances through 6Li and 7Li, with updated nuclear reactions and uncertainties including those in the neutron lifetime. Fits are provided for these results as a function of baryon density and of the number of neutrino flavors Nν. Recent developments are reviewed in BBN, particularly new, precision Planck cosmic microwave background (CMB) measurements that now probe the baryon density, helium content, and the effective number of degrees of freedom Neff. These measurements allow for a tight test of BBN and cosmology using CMB data alone. Our likelihood analysis convolves the 2015 Planck data chains with our BBN output and observational data. Adding astronomical measurements of light elements strengthens the power of BBN. A new determination of the primordial helium abundance is included in our likelihood analysis. New D/H observations are now more precise than the corresponding theoretical predictions and are consistent with the standard model and the Planck baryon density. Moreover, D/H now provides a tight measurement of Nν when combined with the CMB baryon density and provides a 2 σ upper limit Nν<3.2 . The new precision of the CMB and D/H observations together leaves D/H predictions as the largest source of uncertainties. Future improvement in BBN calculations will therefore rely on improved nuclear cross-section data. In contrast with D/H and 4He, 7Li predictions continue to disagree with observations, perhaps pointing to new physics. This paper concludes with a look at future directions including key nuclear reactions, astronomical observations, and theoretical issues.

  16. Status of the MINOS Experiment

    SciTech Connect

    Elizabeth Buckley-Geer

    2003-03-17

    We report on the status of the MINOS long baseline neutrino experiment presently under construction at the Fermi National Accelerator Laboratory and the Soudan mine. There is growing evidence that the solar neutrino and atmospheric neutrino anomalies [1] are the result of neutrino oscillations. The MINOS experiment is a long baseline neutrino oscillation experiment designed to study the region of parameter space indicated by the SuperKamiokande atmospheric neutrino results [2]. The experiment consists of two detectors, one with a mass of 980 tons located at Fermilab (the near detector) and the other of mass 5400 tons located 731 km away in the Soudan mine in northern Minnesota (the far detector). The third component is the neutrino beam which is currently under construction at Fermilab.

  17. ARC EMCS Experiments (Seedling Growth-2) Experiment Status

    NASA Technical Reports Server (NTRS)

    Heathcote, David; Steele, Marianne

    2015-01-01

    Presentation of the status of the ARC ISS (International Space Station) Experiment, Seedling Growth-2 to the Payload Operations Investigator Working Group meeting at MSFC, Huntsville AL. The experiment employs the European Modular Cultivation System (ECMS).

  18. SIRIO-2 - Conception and present status

    NASA Astrophysics Data System (ADS)

    Schiavon, M.; Francesi, M.

    1981-09-01

    The design, objectives and present status of the SIRIO-2 geostationary spin-stabilized satellite to be launched in early 1982 from Kourou, French Guyana are presented. SIRIO-2, the basic design of which was derived from that of its predecessor, SIRIO-1, carries a payload consisting of two experiments: the Meteorological Data Distribution (MOD) experiment, intended to connect African and Asian meteorological stations, and the Laser Synchronization from Synchronous Orbit (LASSO) experiment, for clock synchronization over intercontinental distances with an accuracy of about 1 nsec. Differences in the configurations of SIRIO-1 and 2 are related to the dimensions of the MDD despun S-band antenna, different spin directions and the interface of the spacecraft with the Ariane launcher with the SYLDA double launch system. Development tests have been performed on a mechanical model, an integration model and a flight model employing existing hardware wherever possible, and are currently at the stage of acceptance testing of the flight model, to be followed by mechanical testing, thermal vacuum tests, a leak check, an operational spin test and repeat electrical and physical tests. Delivery to ESA is planned for the middle of November, 1981.

  19. Schedule and status of irradiation experiments

    SciTech Connect

    Rowcliffe, A.F.; Grossbeck, M.L.; Robertson, J.P.

    1998-03-01

    The current status of reactor irradiation experiments is presented in tables summarizing the experimental objectives, conditions, and schedule. Currently, the program has four irradiation experiments in reactor, and five experiments in the design or construction stages. Postirradiation examination and testing is in progress on ten experiments.

  20. Schedule and status of irradiation experiments

    SciTech Connect

    Rowcliffe, A.F.; Grossbeck, M.L.; Robertson, J.P.

    1998-09-01

    The current status of reactor irradiation experiments is presented in tables summarizing the experimental objectives, conditions, and schedule. Currently, the program has one irradiation experiment in reactor and five experiments in the design or construction stages. Postirradiation examination and testing is in progress on ten experiments.

  1. Myxoedema coma presenting in status epilepticus.

    PubMed

    Woods, K L; Holmes, G K

    1977-01-01

    A 71-year-old woman with myxoedema coma presenting in status epilepticus is reported. Although this complication of myxoedema coma is considered to be fatal the patient described responded dramatically to treatment and remains in good health. PMID:876913

  2. National Hydrogen Learning Demonstration Status (Presentation)

    SciTech Connect

    Wipke, K.; Sprik, S.; Kurtz, J.; Ramsden, T.; Ainscough, C.; Saur, G.

    2012-02-01

    This presentation discusses U.S. DOE Learning Demonstration Project goals, fuel cell vehicle and H2 station deployment status, and technical highlights of vehicle and infrastructure analysis results and progress.

  3. Status of the T2K experiment

    NASA Astrophysics Data System (ADS)

    Poutissou, J.-M.

    2011-07-01

    These lectures present the status of the Tokai to Kamioka Experiment (T2K) which just started taking data in early 2010. The goals and methodology for the experiment are presented as well as the challenges and prospects for determining the neutrino mixing parameters leading to neutrino oscillation with a particular attention to the determination of the mixing angle θ13.

  4. Fuel Cell Technology Status - Voltage Degradation (Presentation)

    SciTech Connect

    Kurtz, J.; Wipke,; Sprik, S.; Saur, G.

    2012-06-01

    This presentation describes an independent assessment of fuel cell durability status and discusses the project's relevance to the Department of Energy Hydrogen and Fuel Cells Program; NREL's analysis approach; the FY12 technical accomplishments including the fourth annual publication of results; and project collaborations and future work.

  5. Present status of TOPAZ FASTBUS system

    SciTech Connect

    Ikeda, H.; Tauchi, T.; Yamauchi, M.

    1986-02-01

    The architecture of the data acquisition system for the TOPAZ detector is reviewed, together with the description on the present status of the FASTBUS development. Miniature version of TOPAZ FASTBUS system is currently being set up for the cosmic ray test of the TOPAZ TPC under control of VAX/FPI.

  6. Status of the MEG Experiment

    SciTech Connect

    Maki, Aki

    2008-02-21

    The MEG experiment which searches for {mu}{yields}e{gamma} decays at the sensitivity level of 10{sup -13} is now in its final stage of the preparation. Some data run is expected by the end of the year 2007. The statuses of each detector components are described.

  7. Optical profiling of anticoagulation status (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Tshikudi, Diane M.; Tripathi, Markandey M.; Hajjarian, Zeinab; Nadkarni, Seemantini K.

    2016-02-01

    Defective blood coagulation resulting from excessive procoagulant activity often leads to thrombotic disorders such as stroke and myocardial infarction. A variety of oral and injectable anticoagulant drugs are prescribed to prevent or treat life-threatening thrombosis. However, due to bleeding complications often associated with anticoagulant treatment, routine monitoring and accurate dosing of anticoagulant therapy is imperative. We have developed Optical thromboelastography (OTEG), a non-contact approach that utilizes a drop of whole blood to measure blood coagulation status in patients. Here, we demonstrate the capability of OTEG for rapidly monitoring anticoagulation in whole blood samples. OTEG monitors coagulation status by assessing changes in blood viscosity from temporal intensity fluctuations of laser speckle patterns during clotting. In OTEG a blood drop is illuminated with coherent light and the blood viscosity is measured from the speckle intensity autocorrelation curve, g2 (t). The metrics, clotting time (R+k), clot progression (angle) and maximum clot stiffness (MA) are then extracted. The aim of the current study was to evaluate the accuracy of OTEG in assessing anticoagulation status of common anticoagulants including heparin, argatroban and rivaroxaban status. A dose-dependent prolongation of R+k was observed in anticoagulated blood, which closely corresponded with standard-reference Thromboelastography (TEG) (r 0.87-0.99, P>0.01 for all cases). OTEG angle was unaltered by anticoagulation whereas TEG angle presented a dose-dependent diminution probably linked to clot rupture. In both OTEG and TEG, MA was unaffected by heparin, argatroban or rivaroxaban. We conclude that OTEG can accurately monitor anticoagulation status following treatment, potentially providing a powerful tool for routine monitoring of patients in the doctor's office or in the home setting.

  8. Modeling of enhanced gravity concentrators - present status

    SciTech Connect

    A.K. Majumder; J.P. Barnwal

    2006-01-15

    The majority of the newly developed enhanced gravity concentrators (EGCs) have tremendous potentials for various applications. Therefore, the performance evaluation of these concentrators treating various minerals, coals, heavy metal recovery from tailing dams, etc., have become an active research topic. Several attempts have also been made to develop appropriate mathematical models of individual concentrators. Despite all these efforts, these concentrators have yet to find the widespread applications they deserve. The present status of modeling these EGCs with a brief description of the operating principles and the present applications are, therefore, reviewed in this article. Research needs in this direction are also highlighted.

  9. Present status of information centers (libraries)

    NASA Astrophysics Data System (ADS)

    Suzuki, Keigo; Adachi, Takashi; Kusumi, Yoshihisa; Nishiyama, Mieko; Hirata, Toshiichiro

    Documentation Kondan-Kai (gathering for discussing issues) has conducted the questionnaire which asks present status of information centers of companies. The purpose of this questionnaire was to obtain some tips which would be useful for companies to consider what their information centers should be in a highly informationalized society, and how they should be changing. The results were grouped into the following five sections and analyzed; (1) management system of information center, (2) use condition of information center, (3) management of books and journals, (4) external online information retrieval and (5) management of technical materials generated inside company.

  10. Status of poloidal divertor experiments

    SciTech Connect

    Mahdavi, M.A.

    1986-01-01

    The poloidal divertor was originally proposed as a means of impurity control and helium ash removal. Some variations of the concept were also proposed to achieve radiative cooling of the boundary plasma. The discovery of a regime of improved confinement in beam-heated diverted plasmas has further increased the potential value of this concept for tokamak reactors. This paper reviews the poloidal divertor experiments in ASDEX, Doublet III, and PDX and reviews the status of divertor theory and some aspects of the next-generation experiments.

  11. Present status of the SORTEC SR Facility

    SciTech Connect

    Atoda, N.; Awaji, N.; Kodaira, M.; Kishimoto, T.; Nishino, J.; Koga, K.; Maejima, Y.; Higashigawa, I.; Yanagida, K. )

    1992-01-01

    The status and performance of the SORTEC SR facility is described. Emphasis is placed on the reliable operation and the high performance of the SR source and the status of major systems for x-ray lithography.

  12. ECR ion sources: present status and prospects

    NASA Astrophysics Data System (ADS)

    Melin, G.

    1997-01-01

    Although now widely used for many applications, the electron cyclotron resonance ion sources (ECRIS), an outgrowth of the fusion plasma research, still suffer from some mystification, or at least from a lack of understanding. This article is an attempt to give a broad overview of the today ECRIS activity devoted to the production of highly charged ions: it therefore describes both physics and theory efforts, technology, performances, plans and prospects as well. An important chapter gives the status of understanding the ECRIS behavior, both the current thinking on how they operate and the experimental evidences whenever it is possible. The various existing sources, their design and main features, are then surveyed. At last the present trends of development, the potential directions for future improvement are examined.

  13. CMS: Present status, limitations, and upgrade plans

    SciTech Connect

    Cheung, H.W.K.; /Fermilab

    2011-09-01

    An overview of the CMS upgrade plans will be presented. A brief status of the CMS detector will be given, covering some of the issues we have so far experienced. This will be followed by an overview of the various CMS upgrades planned, covering the main motivations for them, and the various R&D efforts for the possibilities under study. The CMS detector has been working extremely well since the start of data-taking at the LHC as is evidenced by the numerous excellent results published by CMS and presented at this workshop and recent conferences. Less well documented are the various issues that have been encountered with the detector. In the spirit of this workshop I will cover some of these issues with particular emphasis on problems that motivate some of the upgrades to the CMS detector for this decade of data-taking. Though the CMS detector has been working extremely well and expectations are great for making the most of the LHC luminosity, there have been a number of issues encountered so far. Some of these have been described and while none currently presents a problem for physics performance, some of them are expected to become more problematic, especially at the highest Phase 1 luminosities for which the majority of the integrated luminosity will be collected. These motivate upgrades for various parts of the CMS detector so that the current excellent physics performance can be maintained or even surpassed in the realm of the highest Phase 1 luminosities.

  14. Methaqualone ingestion: evaluation of present status.

    PubMed

    Bailey, D N

    1981-01-01

    Sixty cases of methaqualone ingestion have been reviewed from 1977 through 1980. Serum methaqualone concentrations, clinical information, and demographic data were studied in order to define the present status of abuse of this drug. The average user was a 27 year-old man who ingested Quaalude plus at least one additional drug (usually a narcotic analgesic, ethanol, a benzodiazepine, or a barbiturate, in that order). He was admitted to the emergency room with a depressed level of consciousness and a serum methaqualone concentration of 5 +/- 3 mg/L (mean +/- SD). Following a brief period of observation and supportive care, he was discharged from the hospital. Serum methaqualone concentrations showed no significant correlation with the physical findings, except that levels greater than or equal to 9 mg/L were always associated with a depressed level of consciousness, whether or not other drugs were present. Despite strict federal controls, methaqualone abuse appears to be a continuing problem, and analysis for this drug should be part of the toxicology screen.

  15. Neutrino oscillations: present status and outlook

    SciTech Connect

    Schwetz, Thomas

    2008-02-21

    I summarize the status of three-flavour neutrino oscillations with date of Oct. 2007, and provide an outlook for the developments to be expected in the near future. Furthermore, I discuss the status of sterile neutrino oscillation interpretations of the LSND anomaly in the light of recent MiniBooNE results, and comment on implications for the future neutrino oscillation program.

  16. Present Status and Prospects of FIREX Project

    NASA Astrophysics Data System (ADS)

    Mima, K.

    2008-07-01

    The goal of the first phase of Fast Ignition Realization EXperiment (FIREX) project (FIREX-I) is to demonstrate ignition temperature of 5-10 keV, followed by the second phase to demonstrate ignition and burn. Since starting FIREX-I project, plasma physics study in ILE has been devoted to increase the coupling efficiency and to improve compression performance. The heating efficiency can be increased by the following two ways. 1) A previous experiments indicate that the coupling of heating laser to imploded plasmas increases with coating a low-density. foam used in the experiment, low-Z plastic foam is desired for efficient electron transport. (Lei et al. 2006). 2) Electrons generated in the inner surface of the double cone will return by sheathe potential generated between two cones. A 2-D PIC simulation indicates that hot electron confinement is improved by a factor of 1.7 (Nakamura et al. 2007). Further optimization of cone geometry by 2-D simulation will be presented in the workshop. The implosion performance can be improved by three ways. 1) Low-Z plastic layer coating on the outer surface of the cone: The 2D hydro-simulation PINOCO predicts that the target areal density increases by a factor of 2. 2) Br doped plastic layer on a fuel pellet may significantly moderate the Rayleigh-Taylor instability (Fujioka et al. 2004), making implosion more stable. 3) Reducing vapor gas pressure in a pellet is necessary to suppress strength of a jet that will destroy the cone tip. (Stephens et al. 2005). As for the cryogenic target fabrication, R&D of fabricating foam cryogenic cine shell target are under development by the joint group between Osaka Univ. and NIFS. The amplifier system of the heating laser LFEX is completed in March 2008. The amplification test has demonstrated laser energy of 3 kJ/beam at 3nm bandwidth. The equivalent 12 kJ in 4 beams meets the specification of LFEX. The large tiled gratings for pulse compressor are completed and installed. The short pulse

  17. [Present status of clinical and fundamental threpsology].

    PubMed

    Kostiuchenko, L N; Ruchkina, I N; Kuz'mina, T N

    2009-01-01

    A good nutrition status is one of the impotant prerequisites of good health. Malnutrition in hospital leads to increased complication, morbidity and mortality rates. Whenever the gastrointestinal tract cannot fulfil its function or must be rested (during intestinal desease), parenteral administration of nutrients (or simultative parenteral and enteral alimitation) is necessary. Nowday perspectives of nutrition support in patients whith intestinal deseases, methods of easily diagnosed of malnutrition are the problems of this article. PMID:19552018

  18. ATLAS experimental equipment. November 1983 workshop and present status

    SciTech Connect

    Not Available

    1984-01-01

    The latest workshop was held in November 1983 with the purpose of presenting an overview of the experimental stations planned for ATLAS, describing the current status of each individual apparatus, soliciting final input on devices of the first phase (i.e. on those that will be ready when beams from ATLAS become available in late Spring of 1985), and discussing and collecting new ideas on equipment for the second phase. There were short presentations on the status of the various projects followed by informal discussions. The presentations mainly concentrated on new equipment for target area III, but included some descriptions of current apparatus in target area II that might also be of interest for experiments with the higher-energy beams available in area III. The meeting was well attended with approx. 50 scientists, approximately half of them from institutions outside Argonne. The present proceedings summarize the presentations and discussions of this one-day meeting. In addition we take the opportunity to include information about developments since this meeting and an update of the current status of the various experimental stations. We would like to emphasize again that outside-user input is extremely welcome.

  19. Status of the MAJORANA DEMONSTRATOR experiment

    SciTech Connect

    Martin, R. D.; Abgrall, N.; Chan, Y-D.; Hegai, A.; Mertens, S.; Poon, A. W. P.; Vetter, K.; Aguayo, E.; Fast, J. E.; Hoppe, E. W.; Kouzes, R. T.; LaFerriere, B. D.; Orrell, J. L.; Overman, N. R.; Soin, A.; Avignone III, F. T.; Barabash, A. S.; Konovalov, S. I.; Yumatov, V.; Bertrand, F. E.; and others

    2014-06-24

    The MAJORANA DEMONSTRATOR neutrinoless double beta-decay experiment is currently under construction at the Sanford Underground Research Facility in South Dakota, USA. An overview and status of the experiment are given.

  20. Status of the MAJORANA DEMONSTRATOR experiment

    SciTech Connect

    Martin, R. D.; Abgrall, N.; Aguayo, Estanislao; Avignone, F. T.; Barabash, Alexander S.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Caldwell, A. S.; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Combs, Dustin C.; Detwiler, Jason A.; Doe, P. J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S.; Esterline, James H.; Fast, James E.; Finnerty, P.; Fraenkle, Florian; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Green, M.; Gruszko, J.; Guiseppe, Vincente; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, R.; Hoppe, Eric W.; Howard, Stanley; Howe, M. A.; Keeter, K.; Kidd, M. F.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; LaFerriere, Brian D.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, J.; MacMullin, S.; Mertens, S.; Mizouni, Leila; Nomachi, Masaharu; Orrell, John L.; O'Shaughnessy, Mark D.; Overman, Nicole R.; Phillips, David; Poon, Alan; Pushkin, K.; Radford, D. C.; Rielage, Keith; Robertson, R. G. H.; Romero-Romero, E.; Ronquest, M. C.; Schubert, Alexis G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Snyder, N.; Soin, Aleksandr; Suriano, Anne-Marie; Thompson, J.; Timkin, V.; Tornow, W.; Varner, R. L.; Vasilyev, Sergey; Vetter, Kai; Vorren, Kris R.; White, Brandon R.; Wilkerson, J. F.; Xu, W.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir

    2014-07-08

    The MAJORANA DEMONSTRATOR neutrinoless double beta-decay experiment is currently under construction at the Sanford Underground Research Facility in South Dakota, USA. An overview and status of the experiment are given.

  1. Transmutation of Radioactive Nuclear Waste — Present Status and Requirement for the Problem-Oriented Nuclear Database: Approach to Scheduling the Experiments (Reactor, Target, Blanket)

    NASA Astrophysics Data System (ADS)

    Artisyuk, V.; Ignatyuk, A.; Korovin, Yu.; Lopatkin, A.; Matveenko, I.; Stankovskiy, A.; Titarenko, Yu.

    2005-05-01

    Transmutation of nuclear wastes (Minor Actinides and Long-Lived Fission Products) remains an important option to reduce the burden of high-level waste on final waste disposal in deep geological structures. Accelerator-Driven Systems (ADS) are considered as possible candidates to perform transmutation due to their subcritical operation mode that eliminates some of the serious safety penalties unavoidable in critical reactors. Specific requirements to nuclear data necessary for ADS transmutation analysis is the main subject of the ISTC Project ♯2578 which started in 2004 to identify the areas of research priorities in the future. The present paper gives a summary of ongoing project stressing the importance of nuclear data for blanket performance (reactivity behavior with associated safety characteristics) and uncertainties that affect characteristics of neutron producing target.

  2. The Transuranium Elements - Present Status: Nobel Lecture

    DOE R&D Accomplishments Database

    Seaborg, G. T.

    1951-12-12

    The discovery of the transuranium elements and the work done on them up to the present time are reviewed. The properties of these elements, their relationship to other elements, their place in the periodic table, and the possibility of production and identification of other transuranium elements are discussed briefly.

  3. Status and perspectives of the MEG experiment

    NASA Astrophysics Data System (ADS)

    Cei, Fabrizio

    2016-04-01

    We present the status and the perspectives of the MEG experiment which has been searching for the Lepton Flavour Violating decay μ+ → e+γ for several years. In a dataset corresponding to 3.6 × 1014 positive muons stopped on target we didn't find any evidence for this decay and established an upper bound on the μ+ → e+γ branching ratio of 5.7 × 10-13 at 90% C.L., with a sensitivity of 7.7 × 10-13, which improves our world best limit by a factor of 4 and the best previous limit by a factor of 20. Our final dataset is about twice as large than the analyzed sample and the expected final sensitivity of the experiment is ˜ 5 × 10-13. We also discuss the status of the upgrade of the experiment (MEGII) which aims to improve the sensitivity by a further order of magnitude.

  4. Anthrax vaccines: present status and future prospects.

    PubMed

    Kaur, Manpreet; Singh, Samer; Bhatnagar, Rakesh

    2013-08-01

    The management of anthrax remains a top priority among the biowarfare/bioterror agents. It was the Bacillus anthracis spore attack through the US mail system after the September 11, 2001, terrorist attacks in the USA that highlighted the potential of B. anthracis as a bioterrorism agent and the threat posed by its deliberate dissemination. These attacks invigorated the efforts toward understanding the anthrax pathogenesis and development of more comprehensive medical intervention strategies for its containment in case of both natural disease and manmade, accidental or deliberate infection of a non-suspecting population. Currently, efforts are directed toward the development of safe and efficacious vaccines as well as intervention tools for controlling the disease in the advanced fulminant stage when toxemia has already developed. This work presents an overview of the current understanding of anthrax pathogenesis and recent advances made, particularly after 2001, for the successful management of anthrax and outlines future perspectives.

  5. Satellite Ocean Color: Present Status, Future Challenges

    NASA Technical Reports Server (NTRS)

    Gregg, Watson W.; McClain, Charles R.; Zukor, Dorothy J. (Technical Monitor)

    2001-01-01

    We are midway into our 5th consecutive year of nearly continuous, high quality ocean color observations from space. The Ocean Color and Temperature Scanner/Polarization and Directionality of the Earth's Reflectances (OCTS/POLDER: Nov. 1996 - Jun. 1997), the Sea-viewing Wide Field-of-view Sensor (SeaWiFS: Sep. 1997 - present), and now the Moderate Resolution Imaging Spectrometer (MODIS: Sep. 2000 - present) have and are providing unprecedented views of chlorophyll dynamics on global scales. Global synoptic views of ocean chlorophyll were once a fantasy for ocean color scientists. It took nearly the entire 8-year lifetime of limited Coastal Zone Color Scanner (CZCS) observations to compile seasonal climatologies. Now SeaWIFS produces comparably complete fields in about 8 days. For the first time, scientists may observe spatial and temporal variability never before seen in a synoptic context. Even more exciting, we are beginning to plausibly ask questions of interannual variability. We stand at the beginning of long-time time series of ocean color, from which we may begin to ask questions of interdecadal variability and climate change. These are the scientific questions being addressed by users of the 18-year Advanced Very High Resolution Radiometer time series with respect to terrestrial processes and ocean temperatures. The nearly 5-year time series of ocean color observations now being constructed, with possibilities of continued observations, can put us at comparable standing with our terrestrial and physical oceanographic colleagues, and enable us to understand how ocean biological processes contribute to, and are affected by global climate change.

  6. Status of the PAPPA experiment

    NASA Technical Reports Server (NTRS)

    Kogut, Alan

    2006-01-01

    The Primordial Anisotropy Polarization Pathfinder Array (PAPPA) is a balloonborne instrument to measure the polarization of the cosmic microwave background and search for the signature of primordial gravity waves. PAPPA uses a novel marriage of RF phase modulation and millimeter-wave bolometric detectors to produce a "polarimeter-on-a-chip" capable of simultaneously measuring the Stokes I, Q, and U parameters on the sky. I will discuss the current status and future plans for PAPPA.

  7. The present status of hyperthermia in Japan.

    PubMed

    Matsuda, T

    1996-05-01

    The research on hyperthermia in Japan was started by the Hyperthermia Study Group in 1978. Six years later, in 1984, the Japanese Society of Hyperthermic Oncology (JSHO) was established. More and more research has been conducted since then. At present, 215 units of heating equipment are installed for use. Among these, 24% are microwave heating equipment, and 66% are radiofrequency (RF) capacitive heating equipment. A nation-wide survey has revealed that about 60% of hyperthermia therapy involves the treatment of deep-seated tumours by RF capacitive heating and RF intracavitary heating. The treatment of superficial tumours by microwave heating represents another 12.5%. Most of the clinical application in the United States and in Europe is microwave heating of superficial tumours. The different modalities of treatment were thermoradiotherapy in 57.5%, thermochemotherapy in 22.6% and thermochemoradiotherapy in 14.5% of the cases surveyed. Compared to other countries, Japan has the highest number of hyperthermia equipment installed, and the most doctors involved in hyperthermia therapy. The main reasons for the advanced state of hyperthermia research in Japan include the development of excellent heating equipment, high membership in JSHO, grant-in-aid by the Japanese government, and coverage by insurance for this form of therapy. Based on 33 papers selected from two books which the author had edited, the optimal protocol, effectiveness and indication for the use of hyperthermia has been established.

  8. Primary energy: Present status and future perspectives

    NASA Astrophysics Data System (ADS)

    Thielheim, K. O.

    A survey of the base-load energy sources available to humans is presented, starting from the point of view that all energy used is ultimately derived from nuclear processes within the sun. Specific note is made of European energy options, noting the large dependence on imported oil. Detailed exploration of available nuclear fuel resources is carried out, with attention given to fission, fusion, and breeder reactor plants and to the state-of-the-art and technology for each. The problems of nuclear waste disposal are discussed, and long term burial in salt domes is outlined as a satisfactory method of containing the materials for acceptable periods of time. The CO2-greenhouse effect hazards caused by increased usage of coal-derived fuels are considered and precautions to be taken on a global scale to ameliorate the warming effects are recommended. The limitations to hydropower are examined, as are those of tidal power. Solar cells are projected to be produced in GW quantities by the year 2000, while wind-derived electricity is predicted to provide a minimum of 5% of the world energy needs in the future.

  9. The present status of trichinellosis in Thailand.

    PubMed

    Khamboonruang, C

    1991-12-01

    The epidemiology of trichinellosis in northern Thailand may be unique. Since 1962, outbreaks of the disease have occurred almost every year. The Department of Communicable Disease Control, Ministry of Public Health reported 118 discrete outbreaks of the disease, involving 5,400 patients, 95 of whom have died. Epidemiological investigations reveal that the outbreaks have occurred mostly in rural areas, associated with villagers celebrating local and traditional festivals such as the northern Thai New Year, wedding ceremonies, or other festive occasions. In almost all cases the source of infection has been traced to either hilltribe pigs, which are raised like wild animals, or to meat from wild boar. Infection is usually acquired through consumption of a local dish called "lahb," traditionally served during these festivities. This popular dish consists of raw finely chopped meat mixed with spices and chilies and is served nearly raw. Common clinical symptoms of trichinellosis in northern Thailand are fever and myalgia, presenting about two weeks after ingestion of raw meat containing encysted Trichinella larvae. Based on its infectivity for rats and pigs and on alloenzyme typing, the species appears to be Trichinella spiralis. The transmission cycle of trichinellosis in northern Thailand is primarily of a sylvatic type. Hilltribe pigs, wild boars, black bear and jackal are common reservoirs. Man intrudes into the cycle by eating the raw or under-cooked meat of these animals. PMID:1822914

  10. Nucleon decay experiments: status and prospects

    SciTech Connect

    Ayres, D.S.; Beier, E.W.; D'Ettorre Piazzoli, B.; Ernwein, J.; Gaisser, T.K.; Seidel, S.; Sulak, L.R.

    1986-01-01

    We survey the current status and future prospects of experiments to search for nucleon decay. Results from current experiments are summarized, and the background rejection capabilities of various techniques are described. We discuss the prospects for improved sensitivity in the new experiments that are now coming into operation, and the opportunities for the next generation of detectors. 33 refs., 2 figs., 4 tabs.

  11. Status of rare decay experiments

    SciTech Connect

    Littenberg, L.S.

    1984-01-01

    Some results are given for rare muon decay experiments currently running. Also, plans are discussed for rare kaon decay experiments. Some of the events sought come from processes which violate lepton flavor conservation. Several apparatuses used in the search are described. 35 references. (LEW)

  12. Status of the neutrino mass experiment KATRIN

    SciTech Connect

    Bornschein, L.; Bornschein, B.; Sturm, M.; Roellig, M.; Priester, F.

    2015-03-15

    The most sensitive way to determine the neutrino mass scale without further assumptions is to measure the shape of a tritium beta spectrum near its kinematic end-point. Tritium is the nucleus of choice because of its low endpoint energy, superallowed decay and simple atomic structure. Within an international collaboration the Karlsruhe Tritium Neutrino experiment (KATRIN) is currently being built up at KIT. KATRIN will allow a model-independent measurement of the neutrino mass scale with an expected sensitivity of 0.2 eV/c{sup 2} (90% CL). KATRIN will use a source of ultrapure molecular tritium. This contribution presents the status of the KATRIN experiment, thereby focusing on its Calibration and Monitoring System (CMS), which is the last component being subject to research/development. After a brief overview of the KATRIN experiment in Section II the CMS is introduced in Section III. In Section IV the Beta Induced X-Ray Spectroscopy (BIXS) as method of choice to monitor the tritium activity of the KATRIN source is described and first results are presented.

  13. Non-convulsive status epilepticus presenting as a psychiatric condition.

    PubMed

    Walker, M C; Cockerell, O C; Sander, J W

    1996-02-01

    Non-convulsive status epilepticus may present as confusion, behavioural disturbances and psychiatric conditions. We present the case of a 17-year-old man who had episodes of non-convulsive status epilepticus as his only manifestation of epilepsy which was mis-diagnosed as a psychiatric condition for over 10 years. He has had almost complete resolution of his symptoms with the introduction of carbamazepine. Non-convulsive status epilepticus is probably commoner than previously thought, and should be considered as a possible diagnosis in all patients presenting with prolonged episodes of altered consciousness even without other manifestations of epilepsy.

  14. Status of the OPERA experiment

    SciTech Connect

    Russo, A.

    2011-11-23

    The OPERA experiment in the underground Gran Sasso Laboratory (LNGS) has been designed to perform the first detection of neutrino oscillations in direct appearance mode in the muon to tau neutrino channel. The detector is hybrid, being made of an emulsion/lead target and of electronic detectors. It is placed in the CNGS neutrino beam 733 km away from the neutrino source. Runs with CNGS neutrinos were successfully carried out from 2008 and the following years. The analysis of a sample of events corresponding to 1.89x10{sup 19} p.o.t. in the CERN CNGS {nu}{sub {mu}} beam yielded the observation of a first candidate {nu}{sub {tau}} CC interaction. The topology and kinematics of this candidate event is described in detail. The background sources are explained and the significance of the observation of the first {nu}{sub {tau}} event candidate is assessed.

  15. Status of the MANX muon cooling experiment

    SciTech Connect

    Yonehara, K.; Broemmelsiek, D.; Hu, M.; Jansson, A.; Kashikhin, V.S.; Kashikhin, V.V.; Lamm, M.; Lopes, M.; Shiltsev, V.; Yarba, V.; Yu, M.; /Fermilab /Muons Inc., Batavia

    2008-06-01

    A demonstration experiment of six-dimensional (6D) phase space muon beam cooling is a key milestone on the roadmap toward to a real muon collider. In order to achieve this goal, they have designed the Muon Collider and Neutrino Factory Experiment (MANX) channel, which consists of the Helical Cooling Channel (HCC). They discuss the status of the simulation study of the MANX in this document.

  16. Occupational Status and the Experience of Anger

    ERIC Educational Resources Information Center

    Collett, Jessica L.; Lizardo, Omar

    2010-01-01

    Current theories in the sociology of emotions posit contradictory expectations regarding the relationship between status and the relative experience of anger, with some predicting a negative relationship and others proposing a positive one. We test the compatibility of these opposing hypotheses by examining the relationship between anger and a key…

  17. Status of the microwave inverse FEL experiment

    NASA Astrophysics Data System (ADS)

    Yoder, R. B.; Marshall, T. C.; Wang, Mei; Hirshfield, J. L.

    1999-07-01

    A status report is presented on an inverse free-electron-laser accelerator experiment operating in the microwave regime (1). This proof-of-principle electron accelerator is powered by up to 15 MW of RF power at 2.86 GHz, which propagates in a smooth-walled circular waveguide surrounded by a pulsed bifilar helical undulator: solenoids provide an axial guiding magnetic field. Undulator pitch, which is initially 11.75 cm, is up-tapered to 13.5 cm over the 1-meter length of the structure to maintain acceleration gradient. Numerical computations predict an energy gain of 0.7 MeV using a 6 MeV injected beam from a 2-1/2 cell RF gun, with small energy spread and strong phase trapping. The maximum attainable acceleration gradient with such a design, using 150 MW of RF power at 34 GHz, is estimated to be at least 30 MV/m. Results from bench tests of the structure and undulator are presented, along with preliminary beam measurements.

  18. Status Cataplecticus as Initial Presentation of Late Onset Narcolepsy

    PubMed Central

    Panda, Samhita

    2014-01-01

    Narcolepsy, one of the important causes of hypersomnia, is an under diagnosed sleep disorder. It has a bimodal age of onset around 15 and 35 years. It is characterized by the tetrad of excessive daytime sleepiness, cataplexy, hypnagogic/ hypnopompic hallucinations, and sleep paralysis. Cataplexy is by far the most predictive feature of narcolepsy. Status cataplecticus is the occurrence of cataplexy repeatedly for hours or days, a rare presentation of narcolepsy. This report describes an elderly gentleman with late onset narcolepsy in the sixth decade of life presenting with initial and chief symptom of status cataplecticus. Citation: Panda S. Status cataplecticus as initial presentation of late onset narcolepsy. J Clin Sleep Med 2014;10(2):207-209. PMID:24533005

  19. Status cataplecticus as initial presentation of late onset narcolepsy.

    PubMed

    Panda, Samhita

    2014-02-15

    Narcolepsy, one of the important causes of hypersomnia, is an under diagnosed sleep disorder. It has a bimodal age of onset around 15 and 35 years. It is characterized by the tetrad of excessive daytime sleepiness, cataplexy, hypnagogic/ hypnopompic hallucinations, and sleep paralysis. Cataplexy is by far the most predictive feature of narcolepsy. Status cataplecticus is the occurrence of cataplexy repeatedly for hours or days, a rare presentation of narcolepsy. This report describes an elderly gentleman with late onset narcolepsy in the sixth decade of life presenting with initial and chief symptom of status cataplecticus. PMID:24533005

  20. Present Status of the Communication Discipline in India.

    ERIC Educational Resources Information Center

    Jain, Nemi C.

    An understanding of the present status of the teaching of communication in India is necessary to facilitate both the discipline's growth and the intercultural communication among scholars concerning communication education. Primary schools do not teach communication courses, and secondary schools include only a minimal amount of communication…

  1. Status of the OLYMPUS Experiment at DESY

    SciTech Connect

    Kohl, M.

    2011-10-24

    The OLYMPUS experiment at DESY, Hamburg, Germany will definitively determine the effect of two-photon exchange in elastic lepton-proton scattering by precisely measuring the ratio of positron-proton to electron-proton elastic unpolarized cross sections. In this paper, the physics motivation is summarized, aspects of the experimental setup are discussed and the current status and timeline of the project are reviewed.

  2. Nova power systems: status and operating experience

    SciTech Connect

    Whitham, K.; Merritt, B.T.; Gritton, D.G.; Smart, A.J.; Holloway, R.W.; Oicles, J.A.

    1983-11-28

    This paper describes the pulse power systems that are used in these lasers; the status and the operating experiences. The pulsed power system for the Nova Laser is comprised of several distinct technology areas. The large capacitor banks for driving flashlamps that excite the laser glass is one area, the fast pulsers that drive pockels cell shutters is another area, and the contol system for the pulsed power is a third. This paper discusses the capacitor banks and control systems.

  3. CDMS experiment: current status and future

    SciTech Connect

    Yoo, Jonghee; /Fermilab

    2007-11-01

    We present the current status of the Cryogenic Dark Matter Search (CDMS). The five tower detector array, total 30 detectors, are running stable since October 2006. We have accumulated more than 900 kg-days of low background data. We also summarize the prospect of SuperCDMS project.

  4. The MEG experiment at PSI: status and prospects

    SciTech Connect

    Signorelli, Giovanni

    2006-07-11

    The present status of the MEG experiment at PST is reviewed. This experiment aims at measuring the branching ratio of the lepton flavor violating process {mu}+ {yields} e+{gamma} with a sensitivity two orders of magnitude below the present experimental limit, set to 1.2 x 10 -11 by the MEGA experiment. The positron momentum will be measured by a set of drift chambers inside a non-homogeneous magnetic field while the photon four-momentum will be measured by an innovative homogeneous liquid xenon scintillation calorimeter. The experiment is now in an advanced construction stage and it is scheduled to start engineering runs during the year 2006.

  5. The status of the Storage Ring EDM experiment

    SciTech Connect

    Semertzidis, Yannis K.

    2009-12-17

    The status of the storage ring experiment capable of probing the proton and deuteron EDM at the 10{sup -29} e.cm level is presented here. At this level it will be sensitive to a new physics mass scale of {approx}300 TeV. If there is new physics at the LHC, it will be sensitive to 10{mu}rad CP-violating phase level making it the most sensitive experiment for CP-violation beyond the SM.

  6. Present status and problems on extraction of uranium from seawater

    SciTech Connect

    Not Available

    1980-07-01

    The Research Committee on Extraction of Uranium from Seawater worked on the technical survey of the present situation of the above technique and the exchange of information among the members, during 1977 to 1979. This is a report of its activity and present status of the research in this field. It includes the development of various adsorbents, extraction of uranium by flotation, various kinds of chemical analyses, some comparisons among different kinds of seawater contacting systems, the secondary concentrations and the cost of assessment.

  7. Status and Prospects for Hadron Production Experiments

    SciTech Connect

    Schroeter, Raphaeel

    2010-03-30

    The latest results from the HARP, MIPP and NA61 Hadron Production Experiments are reviewed and their implications for neutrinos physics experiments are discussed. We emphasize three neutrino sources: accelerator-based neutrino beams, advanced neutrino sources and atmospheric neutrinos. Finally, prospects from additional forthcoming hadron production measurements are presented.

  8. Early Detection of Fetal Malformation, a Long Distance Yet to Cover! Present Status and Potential of First Trimester Ultrasonography in Detection of Fetal Congenital Malformation in a Developing Country: Experience at a Tertiary Care Centre in India

    PubMed Central

    Kashyap, Namrata; Pradhan, Mandakini; Singh, Neeta; Yadav, Sangeeta

    2015-01-01

    Background. Early detection of malformation is tremendously improved with improvement in imaging technology. Yet in a developing country like India majority of pregnant women are not privileged to get timely diagnosis. Aims and Objectives. To assess the present status and potential of first trimester ultrasonography in detection of fetal congenital structural malformations. Methodology. This was a retrospective observational study conducted at Sanjay Gandhi Postgraduate Institute of Medical Sciences. All pregnant women had anomaly scan and women with fetal structural malformations were included. Results. Out of 4080 pregnant women undergoing ultrasound, 312 (7.6%) had fetal structural malformation. Out of 139 patients who were diagnosed after 20 weeks, 47 (33.8%) had fetal structural anomalies which could have been diagnosed before 12 weeks and 92 (66.1%) had fetal malformations which could have been diagnosed between 12 and 20 weeks. Conclusion. The first trimester ultrasonography could have identified 50% of major structural defects compared to 1.6% in the present scenario. This focuses on the immense need of the hour to gear up for early diagnosis and timely intervention in the field of prenatal detection of congenital malformation. PMID:26759727

  9. Status and prospects of the SNO+ experiment

    NASA Astrophysics Data System (ADS)

    Maneira, J.

    2016-05-01

    The SNO+ experiment is located at the SNOLAB underground laboratory and will employ 780 tons of liquid scintillator loaded, in its initial phase, with 800 kg of 130Te (0.3% by mass) for a low-background and high-isotope-mass search for neutrino-less double beta decay. SNO+ reuses the acrylic vessel and PMT array of the SNO detector, but several experimental upgrades and adaptations were necessary to allow for the use of liquid scintillator. The SNO+ technique allows a staged approach, and extensive R&D is ongoing to increase the loadings and improve the purification of Tellurium. The very good conditions of background and low energy threshold allow SNO+ to also have other physics topics in its program, including geo- and reactor neutrinos, Supernova and solar neutrinos. This talk will describe the main advantages and challenges of the SNO+ approach for the double-beta decay program, the current status of the experiment and its sensitivity prospects.

  10. Present status of refurbishment and irradiation technologies in JMTR

    NASA Astrophysics Data System (ADS)

    Inaba, Yoshitomo; Ishihara, Masahiro; Niimi, Motoji; Kawamura, Hiroshi

    2011-10-01

    The Japan Materials Testing Reactor (JMTR) of the Japan Atomic Energy Agency is a testing reactor for various neutron irradiation tests on nuclear fuels and materials, as well as for radioisotope production. The operation of JMTR stopped temporarily in August 2006 for refurbishment and improvement. The renewed JMTR will resume operation in Japanese fiscal year 2011. The renewal of aged reactor components, the preparation of new irradiation facilities, and the development of irradiation technologies have been carried out for the resumption of the new JMTR. The new JMTR with the new irradiation facilities and the irradiation technologies will be utilized for the research and development of fission and fusion reactor fuels and materials. This paper describes the present status of the refurbishment and the irradiation technologies focused on instrumentation such as the multi-paired thermocouple which is applicable to irradiation temperature control and a ceramic oxygen sensor in JMTR.

  11. Status of advanced carbide fuels: Past, present, and future

    NASA Astrophysics Data System (ADS)

    Anghaie, Samim; Knight, Travis

    2002-01-01

    Solid solution, mixed uranium/refractory metal carbide fuels such as (U, Zr, Nb)C, so called ternary carbide or tri-carbide fuels have great potential for applications in next generation advanced nuclear power reactors. Because of their high melting points, high thermal conductivity, improved resistance to hot hydrogen corrosion, and good fission product retention, these advanced nuclear fuels have great potential for high performance reactors with increased safety margins. Despite these many benefits, some concerns regarding carbide fuels include compatibility issues with coolant and/or cladding materials and their endurance under the extreme conditions associated with nuclear thermal propulsion. The status of these fuels is reviewed to characterize their performance for space nuclear power applications. Results of current investigations are presented and as well as future directions of study for these advanced nuclear fuels. .

  12. Present Status of Networking Conditions in Univ. of South Pacific

    NASA Astrophysics Data System (ADS)

    Takahashi, Fujinobu

    Three years program of Japanese Info-Communication Technology (ICT) Capacity Building Project in the University of South Pacific (USP) will terminate in June 2005. Japanese government has a plan of the new Pacific ICT Center program in USP from 2006. The author will introduce the recent status of USP networking conditions both of satellite and marine cable. The present global VLBI (and even GPS/IGS) network has a weak point of asymmetric distribution by very few number or luck of stations in the huge south Pacific/water hemisphere because of many difficulties such as narrow/poor telecommunication line. It is very important and urgent matters to enhance the space geodetic activities in USP.

  13. Status of Meson Photoproduction Experiments with CLAS

    SciTech Connect

    Pasyuk, Eugene A.

    2014-01-01

    A large part of the experimental program in Hall B of the Jefferson Lab is dedicated to baryon spectroscopy. Meson photoproduction experiments are essential part of this program. CEBAF Large Acceptance Spectrometer (CLAS) and availability of circularly and linearly polarized tagged photon beams in combination with longitudinally and transversely polarized frozen spin targets provide unique conditions for this type of experiments. For the first time, a complete or nearly complete measurement became possible and will allow model independent extraction of the reaction amplitude. The measurements were complete with both proton and deuteron targets. An overview of the collected experimental data will be presented.

  14. CRUDE OIL BIOREMEDIATION: THE AMERICAN EXPERIENCE (PRESENTATION)

    EPA Science Inventory

    This is a state-of-the-art extended abstract presentation summary of the outputs from the oil spill program over the last 11 years. It summarizes the results of 3 field studies involving intentional releases of crude oil: the Delaware study in 1994 (sandy beach), the St. Lawrence...

  15. Status of the Daya Bay Reactor Neutrino Oscillation Experiment

    SciTech Connect

    Daya Bay Collaboration; Lin, Cheng-Ju Stephen

    2010-12-15

    The last unknown neutrino mixing angle theta_13 is one of the fundamental parameters of nature; it is also a crucial parameter for determining the sensitivity of future long-baseline experiments aimed to study CP violation in the neutrino sector. Daya Bay is a reactor neutrino oscillation experiment designed to achieve a sensitivity on the value of sin^2(2*theta_13) to better than 0.01 at 90percent CL. The experiment consists of multiple identical detectors placed underground at different baselines to minimize systematic errors and suppress cosmogenic backgrounds. With the baseline design, the expected anti-neutrino signal at the far site is about 360 events per day and at each of the near sites is about 1500 events per day. An overview and current status of the experiment will be presented.

  16. Orbital retinoblastoma: Present status and future challenges – A review

    PubMed Central

    Ali, Mohammad J.; Honavar, Santosh G.; Reddy, Vijay A.P.

    2010-01-01

    Orbital retinoblastoma is a catastrophic event traditionally carrying a dismal prognosis. Although its incidence is less in the developed countries it continues to be one of the major diagnosis at presentation in the developing world. Orbital retinoblastoma encompasses a wide range of distinct clinical entities with varying tumor load. There are no standard treatment protocols as of now but the current preferred management is multimodal with a combination of initial high-dose chemotherapy, surgery, external beam radiotherapy and prolonged chemotherapy for twelve cycles. In spite of progress on all fronts including surgical, medical, diagnostic, genetic and rehabilitative with improving survival rates, however, lack of access to medical facilities, lack of education about the need for early medical attention and cultural resistance to enucleation continue to contribute to an epidemic of extra ocular disease at diagnosis in the developing world. This review introduces the various terminologies used in the spectrum of orbital retinoblastoma, discusses in details the clinical aspects and management protocols, current status and the future directions. PMID:23960917

  17. Progress and present status of ITER cryoline system

    SciTech Connect

    Badgujar, S.; Bonneton, M.; Chalifour, M.; Forgeas, A.; Serio, L.; Sarkar, B.; Shah, N.

    2014-01-29

    The cryoline system at ITER forms a very complex network localized inside the Tokamak building, on a dedicated plant bridge and in cryoplant areas. The cooling power produced in the cryoplant is distributed via these lines with a total length of about 3.7 km and interconnecting all the cold boxes of the cryogenic system as well as the cold boxes of various clients (magnets, cryopumps and thermal shield). Distinct layouts and polygonal geometry, nuclear safety and confinement requirements, difficult installation and in-service inspection/repair demand very high reliability and availability for the cryolines. The finalization of the building-embedded plates for supporting the lines, before the detailed design, has made this project technologically more challenging. The conceptual design phase has been completed and procurement arrangements have been signed with India, responsible for providing the system of cryolines and warm lines to ITER, as in kind contribution. The prototype test for the design and performance validation has been planned on a representative cryoline section. After describing the basic features and general layout of the ITER cryolines, the paper presents key design requirements, conceptual design approach, progress and status of the cryolines project as well as challenges to build such a complex cryoline system.

  18. Design of the muon collider lattice: Present status

    SciTech Connect

    Garren, A.; Courant, E.; Gallardo, J.

    1996-05-01

    The last component of a muon collider facility, as presently envisioned, is a colliding-beam storage ring. Design studies on various problems for this ring have been in progress over the past year. In this paper we discuss the current status of the design. The projected muon currents require very low beta values at the IP, {beta}* = 3 mm, in order to achieve the design luminosity of L = 10{sup 35} cm{sup -2} s{sup -1}. The beta values in the final-focus quadrupoles are roughly 400 km. To cancel the corresponding chromaticities, sextupole schemes for local correction have been included in the optics of the experimental insertion. The hour-glass effect constraints the bunch length to be comparable too. To obtain such short bunches with reasonable rf voltage requires a very small value of the momentum compaction a, which can be obtained by using flexible momentum compaction (FMC) modules in the arcs. A preliminary design of a complete collider ring has now been made; it uses an experimental insertion and arc modules as well as a utility insertion. The layout of this ring is shown schematically, and its parameters are summarized. Though some engineering features are unrealistic, and the beam performance needs some improvement, we believe that this study can serve as the basis for a workable collider design. The remaining sections of the paper will describe the lattice, show beam behaviour, and discuss future design studies.

  19. Iodine status in the Nordic countries – past and present

    PubMed Central

    Nyström, Helena Filipsson; Brantsæter, Anne Lise; Erlund, Iris; Gunnarsdottir, Ingibjörg; Hulthén, Lena; Laurberg, Peter; Mattisson, Irene; Rasmussen, Lone Banke; Virtanen, Suvi; Meltzer, Helle Margrete

    2016-01-01

    Background Adequate iodine nutrition is dependent on ground water content, seafood, and, as many countries use iodized cow fodder, dairy products. In most countries, salt fortification programs are needed to assure adequate iodine intake. Objectives The objectives are threefold: 1) to describe the past and present iodine situation in the Nordic countries, 2) to identify important gaps of knowledge, and 3) to highlight differences among the Nordic countries’ iodine biomonitoring and fortification policies. Design Historical data are compared with the current situation. The Nordic countries’ strategies to achieve recommended intake and urine iodine levels and their respective success rates are evaluated. Results In the past, the iodine situation ranged from excellent in Iceland to widespread goiter and cretinism in large areas of Sweden. The situation was less severe in Norway and Finland. According to a 1960 World Health Organization (WHO) report, there were then no observations of iodine deficiency in Denmark. In Sweden and Finland, the fortification of table salt was introduced 50–75 years ago, and in Norway and Finland, the fortification of cow fodder starting in the 1950s helped improve the population's iodine status due to the high intake of milk. In Denmark, iodine has been added to household salt and salt in bread for the past 15 years. The Nordic countries differ with regard to regulations and degree of governmental involvement. There are indications that pregnant and lactating women, the two most vulnerable groups, are mildly deficient in iodine in several of the Nordic countries. Conclusion The Nordic countries employ different strategies to attain adequate iodine nutrition. The situation is not optimal and is in need of re-evaluation. Iodine researchers, Nordic national food administrations, and Nordic governmental institutions would benefit from collaboration to attain a broader approach and guarantee good iodine health for all. PMID:27283870

  20. Status of the Borexino Solar Neutrino Experiment, 2006

    SciTech Connect

    McCarty, Kevin B.

    2006-11-17

    The Borexino experiment is designed to measure the flux of 7Be solar neutrinos. The experiment, having a 100-ton fiducial volume of organic liquid scintillator, should detect roughly 35 neutrinos per day in the energy range 250 - 1300 keV, a range lower than that of any previous real-time neutrino detector. Though the 862-keV 7Be neutrinos make up roughly 10% of the total solar neutrino flux, they have not previously been directly observed. Their energy is at a delicate point for confirmation of the vacuum-to-matter oscillation transition. In these proceedings, I will present the status of the Borexino experiment as of August 2006, as we prepare for final filling of the detector.

  1. National Fuel Cell Vehicle Learning Demonstration: Status and Results (Presentation)

    SciTech Connect

    Wipke, K.; Sprik, S.; Kurtz, J.; Ramsden, T.; Garbak, J.

    2009-04-22

    The objectives of this paper are: (1) validate H{sub 2} FC vehicles and infrastructure in parallel; (2) identify current status and evolution of the technology; (3) objectively assess progress toward technology readiness; and (4) provide feedback to H{sub 2} research and development.

  2. Illiteracy, Sex and Occupational Status in Present-Day China.

    ERIC Educational Resources Information Center

    Lamontagne, Jacques

    This study determined the magnitude of disparity between men and women in China in relation to illiteracy and occupational status. Region and ethnicity are used as control variables. The data collected are from a 10 percent sampling of the 1982 census; the total sample size includes a population of 100,380,000 nationwide. The census questionnaire…

  3. The german microgravity program: Objectives and present status

    NASA Astrophysics Data System (ADS)

    Greger, G.; Strub, H.; Wagner, M.

    Within the space program of the Federal Republic of Germany the microgravity program in connection with the utilization of SPACELAB constitutes a central task which determines the long-term program concepts and also their relation to German participation in future ESA programs. The scientific preparatory programs under way for some years now have made further progress. Extensive flight experience and valuable scientific results were obtained on the basis of successful rocket pre-programs. The present paper describes the process in which scientific and organisational priorities are being defined for the planning and execution of the experimental programs. In order to obtain a sufficient number of flight opportunities, payloads for SPACE SHUTTLE missions, in particular under the NASA GAS Program, as well as experimental equipment such as the materials laboratory (MSDR) for FSLP are being developed. The German program focuses on preparing a German SPACELAB mission D1 planned for 1985, which is intended to verify the applicability and efficiency of manned research laboratories for industry and the scientific community. A second emphasis is on preparing the use of SHUTTLE-supported re-usable space platforms.

  4. Present status and perspective of pharmacogenetics in Mexico.

    PubMed

    Cuautle-Rodríguez, Patricia; Llerena, Adrián; Molina-Guarneros, Juan

    2014-01-01

    Drug costs account for up to 24% of the country's health expenditure and there are 13,000 registered drugs being prescribed. Diabetes is the main cause of death in the country, with over 85% of diabetic patients currently under drug treatment. The importance of knowing interindividual variability in drug metabolism on Mexican populations is thus evident. The purpose of this article is to provide an overlook of the current situation of pharmacogenetic research in Mexico, focusing on drug-metabolizing enzymes, and the possibility of developing a phenotyping cocktail for Mexican populations. So far, 21 pharmacogenetic studies on Mexican population samples (Mestizos and Amerindian) have been published. These have reported interindividual variability through phenotyping and/or genotyping cytochromes: CYP2D6, 2C19, 2C9, 2E1, and phase II enzymes UGT and NAT2. Some cytochromes with important clinical implications have not yet been phenotyped in Mexican populations. The development of a cocktail adapted to them could be a significant contribution to a larger knowledge on drug response variability at a lower price and shorter time. There are validated phenotyping cocktails that present several practical advantages, being valuable, safe, and inexpensive tools in drug metabolism characterization, which require only a single experiment to provide information on several cytochrome activities. PMID:24129103

  5. Groundwater Storage Changes: Present Status from GRACE Observations

    NASA Astrophysics Data System (ADS)

    Chen, Jianli; Famigliett, James S.; Scanlon, Bridget R.; Rodell, Matthew

    2016-03-01

    Satellite gravity measurements from the Gravity Recovery and Climate Experiment (GRACE) provide quantitative measurement of terrestrial water storage (TWS) changes with unprecedented accuracy. Combining GRACE-observed TWS changes and independent estimates of water change in soil and snow and surface reservoirs offers a means for estimating groundwater storage change. Since its launch in March 2002, GRACE time-variable gravity data have been successfully used to quantify long-term groundwater storage changes in different regions over the world, including northwest India, the High Plains Aquifer and the Central Valley in the USA, the North China Plain, Middle East, and southern Murray-Darling Basin in Australia, where groundwater storage has been significantly depleted in recent years (or decades). It is difficult to rely on in situ groundwater measurements for accurate quantification of large, regional-scale groundwater storage changes, especially at long timescales due to inadequate spatial and temporal coverage of in situ data and uncertainties in storage coefficients. The now nearly 13 years of GRACE gravity data provide a successful and unique complementary tool for monitoring and measuring groundwater changes on a global and regional basis. Despite the successful applications of GRACE in studying global groundwater storage change, there are still some major challenges limiting the application and interpretation of GRACE data. In this paper, we present an overview of GRACE applications in groundwater studies and discuss if and how the main challenges to using GRACE data can be addressed.

  6. Present status and perspective of pharmacogenetics in Mexico.

    PubMed

    Cuautle-Rodríguez, Patricia; Llerena, Adrián; Molina-Guarneros, Juan

    2014-01-01

    Drug costs account for up to 24% of the country's health expenditure and there are 13,000 registered drugs being prescribed. Diabetes is the main cause of death in the country, with over 85% of diabetic patients currently under drug treatment. The importance of knowing interindividual variability in drug metabolism on Mexican populations is thus evident. The purpose of this article is to provide an overlook of the current situation of pharmacogenetic research in Mexico, focusing on drug-metabolizing enzymes, and the possibility of developing a phenotyping cocktail for Mexican populations. So far, 21 pharmacogenetic studies on Mexican population samples (Mestizos and Amerindian) have been published. These have reported interindividual variability through phenotyping and/or genotyping cytochromes: CYP2D6, 2C19, 2C9, 2E1, and phase II enzymes UGT and NAT2. Some cytochromes with important clinical implications have not yet been phenotyped in Mexican populations. The development of a cocktail adapted to them could be a significant contribution to a larger knowledge on drug response variability at a lower price and shorter time. There are validated phenotyping cocktails that present several practical advantages, being valuable, safe, and inexpensive tools in drug metabolism characterization, which require only a single experiment to provide information on several cytochrome activities.

  7. Natural analogue studies: present status and performance assessment implications

    NASA Astrophysics Data System (ADS)

    Smellie, John A. T.; Karlsson, Fred; Alexander, W. Russell

    1997-04-01

    Studies of natural geological and archaeological systems as analogues to long-term processes, which are predicted to occur within a radioactive waste repository environment, have become increasingly popular over the last 10 years or so, to the extent that such studies form an integral part of many national programmes for radioactive waste disposal. There is now a common consensus that the natural analogue approach is a very useful scientific methodology to: (a) identify and understand processes and mechanisms analogous to those which could occur in the vicinity of a repository over realistic timescales, (b) derive input data which have been successfully used to test some of the laboratory-based models which form the basis of long-term repository performance assessment, and (c) to produce data which can be input directly to performance assessment models. Increasingly, analogues are playing an important role in public awareness, enabling the layman to understand better the concept of radioactive disposal and demonstrating the reliability of the disposal system over long periods of geological time. The complexity of geological systems means that it is very often difficult and sometimes impossible to quantify precisely the physico-chemical boundary conditions necessary to model a particular geochemical process or mechanism. Consequently, the availability of quantitative analogue data is limited when repository performance assessments are considered. However, this in no way detracts from their value in building confidence by demonstrating that important processes do exist and by showing qualitatively that they behave in a way predicted by models based on laboratory-derived data. The transfer of natural analogue data from the complexity of field studies to simplistic models which, by necessity, are used in performance assessments, is an area of activity which is presently being addressed. Field analogue studies are now being planned to interface with laboratory

  8. Status of the hydrogen and deuterium atomic beam polarized target for NEPTUN experiment

    NASA Astrophysics Data System (ADS)

    Balandikov, N. I.; Ershov, V. P.; Fimushkin, V. V.; Kulikov, M. V.; Pilipenko, Yu. K.; Shutov, V. B.

    1995-09-01

    NEPTUN-NEPTUN-A is a polarized experiment at Accelerating and Storage Complex (UNK, IHEP) with two internal targets. Status of the atomic beam polarized target that is being developed at the Joint Institute for Nuclear Research, Dubna is presented.

  9. Present Status of Subclinical Intestinal Malabsorption in the Tropics

    PubMed Central

    Falaiye, J. M.

    1971-01-01

    A review of the literature on subclinical intestinal disease shows its probable relevance in certain nutritional deficiencies in the indigenous residents of tropical climates. A significant incidence of intestinal disease has been defined among asymptomatic fit-looking adult Nigerians. The results of subsequent investigation into the pathogenesis of this disorder strongly point to hypoalbuminaemia as the important factor capable of producing a biochemically and histologically defined malabsorptive state leading to subnormal nutritional status among members of this community. ImagesFIG. 3 PMID:5125280

  10. Photon Strength Functions below GDER Maximum: Present Status and Outlook

    SciTech Connect

    Krticka, Milan

    2009-01-28

    Existing experimental data on {gamma} decay of energy levels in medium-weight and heavy nuclei at excitation energies well above the pairing gap indicate that the role of nuclear structure effects is small and that this decay is largely governed by the extreme statistical model. Specifically, in line with the validity of Brink hypothesis and the paradigm of photon strength, the average properties of the {gamma} decay can be described by a set of photon strength functions (PSFs) for individual multipolarities and by the level density function. PSFs are directly related to the photoabsorption cross sections {sigma}{sub {gamma}}{sub abs}. It is well known that in the case of E1 radiation this cross section is dominated by the giant dipole electric resonance. However the size of {sigma}{sub {gamma}}{sub abs.} and its {gamma}-ray energy dependence at energies below the neutron threshold are known rather poorly. In the case of higher multipolarities (M1, E2,...) the present knowledge about their roles is much worse. Available information on E1 and M1 PSFs obtained from various kinds of experiments in the {gamma}-ray energy region of interest will be discussed within the widely used models. It will be shown that none of them seems to be able to describe PSFs reasonably for a broad range of nuclei. Emphasis will be also laid on the properties of the scissors mode and other possible resonance-like structures in PSFs at energies below about 10 MeV. Perspectives of further studies of PSFs will be outlined.

  11. Present status of computational tools for maglev development

    SciTech Connect

    Wang, Z.; Chen, S.S.; Rote, D.M.

    1991-10-01

    High-speed vehicles that employ magnetic levitation (maglev) have received great attention worldwide as a means of relieving both highway and air-traffic congestion. At this time, Japan and Germany are leading the development of maglev. After fifteen years of inactivity that is attributed to technical policy decisions, the federal government of the United States has reconsidered the possibility of using maglev in the United States. The National Maglev Initiative (NMI) was established in May 1990 to assess the potential of maglev in the United States. One of the tasks of the NMI, which is also the objective of this report, is to determine the status of existing computer software that can be applied to maglev-related problems. The computational problems involved in maglev assessment, research, and development can be classified into two categories: electromagnetic and mechanical. Because most maglev problems are complicated and difficult to solve analytically, proper numerical methods are needed to find solutions. To determine the status of maglev-related software, developers and users of computer codes were surveyed. The results of the survey are described in this report. 25 refs.

  12. Status of the NOvA experiment

    SciTech Connect

    Plunkett, Robert; /Fermilab

    2007-12-01

    The NOvA experiment, using the existing NuMI beamline, is planned for construction at Ash River, Minnesota. The experiment will provide a measurement of, or strong limit on the neutrino mixing angle {theta}{sub 13}, and for sufficiently strong mixing, establish the hierarchy of the neutrino masses.

  13. The Status of Radiation Damage Experiments

    SciTech Connect

    Strachan, Denis M.; Scheele, Randall D.; Icenhower, Jonathan P.; Kozelisky, Anne E.; Sell, Richard L.; Legore, Virginia L.; Schaef, Herbert T.; O'Hara, Matthew J.; Brown, Christopher F.; Buchmiller, William C.

    2001-11-20

    Experiments have been on-going for about two years to determine the effects that radiation damage have on the physical and chemical properties of candidate titanate ceramics for the immobilization of plutonium. We summarize the results of these experiments in this document.

  14. Trans-Pacific Astronomy Experiment Project Status

    NASA Technical Reports Server (NTRS)

    Hsu, Eddie

    2000-01-01

    The Trans-Pacific Astronomy Experiment is Phase 2 of the Trans-Pacific High Data Rate Satcom Experiments following the Trans-Pacific High Definition Video Experiment. It is a part of the Global Information Infrastructure-Global Interoperability for Broadband Networks Project (GII-GIBN). Provides global information infrastructure involving broadband satellites and terrestrial networks and access to information by anyone, anywhere, at any time. Collaboration of government, industry, and academic organizations demonstrate the use of broadband satellite links in a global information infrastructure with emphasis on astronomical observations, collaborative discussions and distance learning.

  15. Relativity experiment on Helios - A status report

    NASA Technical Reports Server (NTRS)

    Anderson, J. D.; Melbourne, W. G.; Cain, D. L.; Lau, E. K.; Wong, S. K.; Kundt, W.

    1975-01-01

    The relativity experiment on Helios (Experiment 11) uses S-band and Doppler data, and spacecraft-solar-orbital data to measure the effects of general relativity in the solar system and the quadrupole moment in the solar gravitational field. Specifically, Experiment 11 is converned with measuring the following effects: (1) relativistic orbital corrections described by two parameters of the space-time metric which are both equal to unity in Einstein's theory; (2) orbital perturbations caused by a finite quadrupole moment of an oblate sun, described by zonal harmonics in the solar gravitational field.

  16. Present status of beryllide R&D as neutron multiplier

    NASA Astrophysics Data System (ADS)

    Kawamura, H.; Takahashi, H.; Yoshida, N.; Mishima, Y.; Ishida, K.; Iwadachi, T.; Cardella, A.; van der Laan, J. G.; Uchida, M.; Munakata, K.; Sato, Y.; Shestakov, V.; Tanaka, S.

    2004-08-01

    Since 1997, beryllide application as the neutron multiplier has been proposed in Japan and preliminary investigations revealed that some beryllides such as Be 12Ti have excellent properties compared with beryllium metal. Recently, several international R&D programs were performed. Some pebbles of modified Be 12Ti that included the Be phase were obtained by the rotating electrode method. Basic characterization using HIPped Be 12Ti has also been performed. Preliminary experiments indicate that compatibility with stainless steel and tritium breeder materials, deuterium release, natural oxidation and oxidations by steam interaction were better than the behavior of beryllium. Preliminary neutron irradiation effects were studied in JMTR and by charged particle irradiation. It was observed that Be 12Ti has less radiation damage than beryllium. In a future experiment, Japanese Be 12Ti samples will be included in a long European irradiation program on beryllium to produce up to 6000 appm He. This is an IEA collaborative experiment, to evaluate neutron irradiation effects.

  17. Present Status and Future Prospects of Laser Fusion Research at ILE Osaka University

    NASA Astrophysics Data System (ADS)

    Mima, K.; Tanaka, K. A.; Kodama, R.; Johzaki, T.; Nagatomo, H.; Shiraga, H.; Sentoku, Y.; Miyanaga, N.; Azechi, H.; Nakai, M.; Norimatu, T.; Nagai, K.; Sunanara, J.; Nishihara, K.; Taguchi, T.; Sakagami, H.

    2004-02-01

    Reviewed are the present status and future prospects of the laser fusion research at the ILE Osaka. The Gekko XII and Peta Watt laser system have been operated for investigating the implosion hydrodynamics, fast ignition, and the relativistic laser plasma interactions and so on. In particular, the fast ignition experiments with cone shell target have been in progress as the UK and US-Japan collaboration programs. In the experiments, the imploded high density plasmas are heated by irradiating 500 J level peta-watt laser pulse. The thermal neutron yield is found to increase by three orders of magnitude by injecting the peta-watt laser into the cone shell target. The Rayleigh-Taylor instability experiment results are also reviewed is this paper.

  18. Present status and future prospects of IFE and high power laser research in Asia

    NASA Astrophysics Data System (ADS)

    Mima, Kunioki

    2004-12-01

    The present status and future prospects of IFE research and high power laser applications in Asia are reviewed. At ILE, Osaka University, the Gekko XII and the Peta Watt laser system have been operated to investigate implosion hydrodynamics, fast ignition and relativistic laser plasma interactions. In particular, fast ignition experiments with cone shell targets have been carried out as joint UK-Japan and US-Japan collaboration programmes. In the experiments, imploded high density plasmas are heated by a 500 J level petawatt laser pulse. The thermal neutron yield is found to increase by three orders of magnitude by petawatt laser injection to the cone shell target. Laser plasma physics related to laser fusion and other applications has been studied at many institutes in Asia. Areas of research include Rayleigh-Taylor instability experiments, application of extreme ultraviolet radiation sources for lithography, laser particle acceleration, and x-ray lasers, to name a few.

  19. Status of Magnetohydrodynamic Augmented Propulsion Experiment

    NASA Technical Reports Server (NTRS)

    Litchford, Ron J.; Lineberry, John T.

    2007-01-01

    Over the past several years, efforts have been under way to design and develop an operationally flexible research facility for investigating the use of cross-field MHD accelerators as a potential thrust augmentation device for thermal propulsion systems, The baseline configuration for this high-power experimental facility utilizes a 1,5-MW, multi-gas arc-heater as a thermal driver for a 2-MW, MHD accelerator, which resides in a large-bore 2-tesla electromagnet. A preliminary design study using NaK seeded nitrogen as the working fluid led to an externally diagonalized segmented MHD channel configuration based on an expendable beat-sink design concept. The current status report includes a review of engineering/design work and performance optimization analyses and summarizes component hardware fabrication and development efforts, preliminary testing results, and recent progress toward full-up assembly and testing

  20. Photovoltaic manufacturing: Present status, future prospects, and research needs

    SciTech Connect

    Wolden, C.A.; Fthenakis, V.; Kurtin, J.; Baxter, J.; Repins, I.; Shasheen, S.; Torvik, J.; Rocket, A.; Aydil, E.

    2011-03-29

    In May 2010 the United States National Science Foundation sponsored a two-day workshop to review the state-of-the-art and research challenges in photovoltaic (PV) manufacturing. This article summarizes the major conclusions and outcomes from this workshop, which was focused on identifying the science that needs to be done to help accelerate PV manufacturing. A significant portion of the article focuses on assessing the current status of and future opportunities in the major PV manufacturing technologies. These are solar cells based on crystalline silicon (c-Si), thin films of cadmium telluride (CdTe), thin films of copper indium gallium diselenide, and thin films of hydrogenated amorphous and nanocrystalline silicon. Current trends indicate that the cost per watt of c-Si and CdTe solar cells are being reduced to levels beyond the constraints commonly associated with these technologies. With a focus on TW/yr production capacity, the issue of material availability is discussed along with the emerging technologies of dye-sensitized solar cells and organic photovoltaics that are potentially less constrained by elemental abundance. Lastly, recommendations are made for research investment, with an emphasis on those areas that are expected to have cross-cutting impact.

  1. LIPSS status and LIPSS-2 future experiments

    NASA Astrophysics Data System (ADS)

    Boyce, James R.; Afanasev, A.; Baker, O. K.; Beard, K. B.; Biallas, G.; Minarni, M.; Robinson, T. R.; Shinn, M.

    2012-03-01

    The LIght Pseudoscalar and Scalar Search (LIPSS) experiment was the first dark matter experiment to use a photon beam from a high average power free-electron laser (FEL). LIPSS employed the ``Light Shining through a Wall'' (LSW) technique. Results from these laboratory dark matter searches established new boundaries for six possible dark matter particles. In addition, the experimental set-up can be modified for dark energy particle searches using the ``Particles in a Jar'' technique. The LIPSS set-up will be summarized and a brief description of other DM/DE search possibilities (LIPSS-2) with the FEL facility will be discussed.

  2. The MEG experiment: status and perspectives

    SciTech Connect

    Nicolo, Donato

    2010-03-30

    The MEG experiment, a sensitive search for the mu->egamma decay, has started operating in September 2008. Analysis of data collected during the initial three months of operation is still ongoing and soon to be finalized. The detector performance during Run 2008 is reviewed, with remarks on perspectives for Run 2009.

  3. Status of the Wind-Diesel Market (Presentation)

    SciTech Connect

    Baring-Gould, E. I.

    2014-02-01

    This presentation offers an overview of the wind-diesel market, including the range of power systems, recent progress, current energy situation of remote communities, operating projects, current market approaches and ongoing challenges.

  4. Microwave Tokamak Experiment: Overview and status

    SciTech Connect

    Not Available

    1990-05-01

    The Microwave Tokamak Experiment, now under construction at the Laboratory, will use microwave heating from a free-electron laser. The intense microwave pulses will be injected into the tokamak to realize several goals, including a demonstration of the effects of localized heat deposition within magnetically confined plasma, a better understanding of energy confinement in tokamaks, and use of the new free-electron laser technology for plasma heating. 3 figs., 3 tabs.

  5. Analysis status of the Q-weak experiment

    NASA Astrophysics Data System (ADS)

    Kargiantoulakis, Emmanouil; Q-weak Collaboration

    2015-04-01

    The Q-weak Collaboration completed a challenging measurement of the parity-violating asymmetry in elastic electron-proton scattering at the Thomas Jefferson National Accelerator Facility (JLab). The initial result reported here is extracted from the commissioning part of the experiment, constituting about 4% of the full data set, and allowed for the first determination of the weak charge of the proton. The analysis of the full Q-weak data set is ongoing and expected to yield a high precision value for the weak charge, which will place significant constraints to models of physics beyond the standard model. The current status will be presented, with emphasis on analysis efforts to reduce the most important systematic uncertainties of the preliminary result.

  6. Western Interconnection Energy Imbalance Market Status and Prospects (Presentation)

    SciTech Connect

    Milligan, M.; Kirby, B.; King, J.; Beuning, S.

    2011-10-01

    This presentation describes how a new wholesale electricity market for energy imbalance ancillary services could be implemented and operated. Some conclusions of this presentation are: (1) Method for calculating additional reserve requirements due to wind and solar production; (2) EIM results in substantial reduction in reserves requirements and ramping demand; (3) Reduced participation reduces benefits for all but reduces the benefits to non-participants the most; (4) Full participation leads to maximum benefit across the Western Interconnection, up to 42% of total reserve requirement; and (5) Regional EIM implementations have smaller but substantial benefits.

  7. Enzymatic reactors for biodiesel synthesis: Present status and future prospects.

    PubMed

    Poppe, Jakeline Kathiele; Fernandez-Lafuente, Roberto; Rodrigues, Rafael C; Ayub, Marco Antônio Záchia

    2015-01-01

    Lipases are being extensively researched for the production of biodiesel as a "silver bullet" in order to avoid the drawbacks of the traditional alkaline transesterification. In this review, we analyzed the main factors involved in the enzymatic synthesis of biodiesel, focusing in the choice of the immobilization protocol, and the parameters involved in the choice and configuration of the reactors. An extensive discussion is presented about the advantages and disadvantages of each type of reactor and their mode of operation. The current scenario of the market for enzymatic biodiesel and some future prospects and necessary developments are also briefly presented.

  8. The Japanese lunar mission SELENE: Science goals and present status

    NASA Astrophysics Data System (ADS)

    Kato, M.; Sasaki, S.; Tanaka, K.; Iijima, Y.; Takizawa, Y.

    2008-07-01

    The Japanese lunar mission SELENE (SELenological and ENgineering Explorer) has been in development to target launch scheduled 2007 summer by H-IIA rocket. The SELENE is starting final integration test after SAR (System Acceptance Review), SRR (System Reliability Review) and instrument environment test. The SELENE is a remote-sensing mission orbiting 100 km altitude of the Moon for nominal one year and extended some months to collect the data for studying the origin and evolution of the Moon. Fourteen instruments and experiment systems are preparing for studies of the Moon, in the Moon, and from the Moon; global element and mineral compositions, topological structure, gravity field of whole moon, and electromagnetic and particle environment of the Moon. The new data center SOAC (SELENE Operation and data Analysis Center) are completed to construct in JAXA Sagamihara campus, and end-to-end test will be carried out between SOAC and data downlink stations.

  9. The SELENE mission: science goals and present status

    NASA Astrophysics Data System (ADS)

    Kato, M.; Sasaki, S.; Takizawa, Y.

    Japanese lunar mission SELENE has been in development to target launch scheduled 2007 summer by H-IIA rocket The SELENE is starting final integration test after SAR System Acceptance Review SRR System Reliability Review and individual environment test The SELENE is a remote-sensing mission orbiting 100 km altitude of the Moon for nominal one year and extended some months to collect the data for studying the origin and evolution of the Moon Fourteen instruments and experiment systems are preparing for studies of the Moon in the Moon and from the Moon global element and mineral compositions topological structure gravity field of whole moon and electromagnetic and particle environment of the Moon The new data center SOAC SELENE Operation and data Analysis Center are almost completed to construct in JAXA Sagamihara campus and end-to end test will be soon carried out between SOAC and data-downlink stations

  10. PRESENT STATUS OF CHARGE-BREEDING IN KEKCB AT TRIAC

    SciTech Connect

    Oyaizu, M.; Jeong, S. C.; Imai, N.; Fuchi, Y.; Hirayama, Y.; Ishiyama, H.; Miyatake, H.; Okada, M.; Watanabe, Y. X.; Ichikawa, S.; Kabumoto, H.; Matsuda, M.; Osa, A.; Otokawa, Y.

    2009-05-04

    We report a recent experiment about the measurement of wall distribution of ions externally injected for charge-breeding in an electron cyclotron resonance (ECR) ion source. The ions, radioactive and singly charged {sup 111}In, were injected into the ECR ion source (ECRIS) for breeding their charge states at the Tokai Radioactive Ion Accelerator Complex (TRIAC). The residual radioactivity on the wall of the ECR plasma chamber of the source was measured, giving a two-dimensional distribution of the ions failed to be re-extracted during charge breeding. The distribution was decomposed, according to azimuthal symmetry, into three components, asymmetric, 120-degree symmetric, and isotropic ones, whose origins were qualitatively discussed for clarifying ion-losses in the course of charge breeding in ECRIS.

  11. Towards Terahertz MMIC Amplifiers: Present Status and Trends

    NASA Technical Reports Server (NTRS)

    Samoska, Lorene

    2006-01-01

    This viewgraph presentation surveys the fastest Monolithic Millimeter-wave Integrated Circuit (MMIC) amplifiers to date; summarize previous solid state power amp results to date; reviews examples of MMICs, reviews Power vs. Gate periphery and frequency; Summarizes previous LNA results to date; reviews Noise figure results and trends toward higher frequency

  12. Neutrino oscillations: from an historical perspective to the present status

    NASA Astrophysics Data System (ADS)

    Bilenky, S.

    2016-05-01

    The history of neutrino mixing and oscillations is briefly presented. Basics of neutrino mixing and oscillations and convenient formalism of neutrino oscillations in vacuum is given. The role of neutrino in the Standard Model and the Weinberg mechanism of the generation of the Majorana neutrino masses are discussed.

  13. Neutrino oscillations: From a historical perspective to the present status

    NASA Astrophysics Data System (ADS)

    Bilenky, S.

    2016-07-01

    The history of neutrino mixing and oscillations is briefly presented. Basics of neutrino mixing and oscillations and convenient formalism of neutrino oscillations in vacuum are given. The role of neutrino in the Standard Model and the Weinberg mechanism of the generation of the Majorana neutrino masses are discussed.

  14. The Electronic Presentation: A Status Report of International Use.

    ERIC Educational Resources Information Center

    Griffin, Robert E.; And Others

    This paper describes how electronic presentations are currently used by business people. Business people in the United States and Sweden were surveyed to determine how they are using the medium. A questionnaire was mailed to 506 business people in the United States (201 returned) and to 80 business people in Sweden (76 returned). Results are…

  15. LMJ & PETAL Status and first experiments

    NASA Astrophysics Data System (ADS)

    Miquel, J.-L.

    2016-05-01

    The laser Megajoule (LMJ) facility is designed to provide the experimental capabilities to study High Energy Density Physics (HEDP). The LMJ is part of the Simulation Program, which combines improvement of physics models, high performance numerical simulation, and experimental validation. Since the operational commissioning of the LMJ, in October 2014, several experimental campaigns have been achieved. They have demonstrated the good performances of LMJ and demonstrated its aptitudes to perform experiments for the Simulation Program. The PETAL project consists in the addition of one short-pulse (ps) ultra- high-power, high-energy beam (kJ) to the LMJ facility. The first high energy test shots in the compressor stage of PETAL, performed in May 2015, have reached a power of 1.2 PW. PETAL will offer a combination of a very high intensity multi-petawatt beam, synchronized with the nanosecond beams of the LMJ. This combination will expand the LMJ experimental field in HEDP. LMJ-PETAL is open to the academic communities; the first experiments are planned in 2017.

  16. Diagnosis of coronary microvascular dysfunction – Present status

    PubMed Central

    Mittal, S.R.

    2015-01-01

    Definite clinical diagnosis of microvascular angina is not possible with the existing knowledge. Resting electrocardiogram may be normal, and exercise electrocardiogram may be unremarkable. Echocardiography usually does not show regional wall motion abnormalities. Transthoracic Doppler echocardiography can satisfactorily evaluate only left anterior descending coronary artery and that too in some patients. Radio-isotope imaging can detect only severe localized disease. Noninvasive diagnosis needs high index of suspicion. At present, definite diagnosis is based on documentation of normal epicardial coronaries, coronary flow reserve less than 2.5 on adenosine induced hyperemia, and absence of spasm of epicardial coronaries on acetylcholine provocation. Invasive evaluation is costly, needs sophisticated equipments and expertise. Therapeutic and prognostic implications of various parameters remains to be evaluated. At present invasive evaluation is recommended only for patients with intractable symptoms with unconfirmed diagnosis, requiring repeated hospitalization and evaluation with failure of empirical therapy. PMID:26702685

  17. Present status of liquid metal research for a fusion reactor

    NASA Astrophysics Data System (ADS)

    Tabarés, Francisco L.

    2016-01-01

    Although the use of solid materials as targets of divertor plasmas in magnetic fusion research is accepted as the standard solution for the very challenging issue of power and particle handling in a fusion reactor, a generalized feeling that the present options chosen for ITER will not represent the best choice for a reactor is growing up. The problems found for tungsten, the present selection for the divertor target of ITER, in laboratory tests and in hot plasma fusion devices suggest so. Even in the absence of the strong neutron irradiation expected in a reactor, issues like surface melting, droplet ejection, surface cracking, dust generation, etc., call for alternative solutions in a long pulse, high efficient fusion energy-producing continuous machine. Fortunately enough, decades of research on plasma facing materials based on liquid metals (LMs) have produced a wealth of appealing ideas that could find practical application in the route to the realization of a commercial fusion power plant. The options presently available, although in a different degree of maturity, range from full coverage of the inner wall of the device with liquid metals, so that power and particle exhaust together with neutron shielding could be provided, to more conservative combinations of liquid metal films and conventional solid targets basically representing a sort of high performance, evaporative coating for the alleviation of the surface degradation issues found so far. In this work, an updated review of worldwide activities on LM research is presented, together with some open issues still remaining and some proposals based on simple physical considerations leading to the optimization of the most conservative alternatives.

  18. Present status and perspectives of VSAT networks in Europe

    NASA Astrophysics Data System (ADS)

    Mignosa, B.; Desilvio, M.; Leone, P.

    1992-03-01

    A summary is presented of the history of VSAT technologies in Europe, the reasons for their limited success to date, and the important role that these systems will probably play in the near future. Consideration is given to regulatory changes in the EC that will impact upon the growth of VSAT systems in Europe. Attention is given to some of the particular fundamentals which must be considered before the subsequent expansion of these regulatory changes in the European market.

  19. Status and plans of the LUCIFER Experiment

    NASA Astrophysics Data System (ADS)

    Orio, F.

    2011-06-01

    Neutrinoless Double Beta Decay searches are the only way to give an answer to the neutrino mass nature, Dirac or Majorana. These experiments are extremely delicate and the greatest obstacle to improve their sensitivity is the background level that can be achieved. LUCIFER is a project, financed by a ERC-AdG, that would like to build a demonstrator of a technique based on the double read-out (scintillation light + heat) of ZnSe crystals used as bolometers. The goal is to reach a background lower than 0.001 counts/kg/keV/year. Along the way we would like to learn how practical is the enrichment of Se into 82Se, how efficient is the process of crystallization and how radiopure the crystals can be grown. In this talk we will discuss the properties of ZnSe crystals and sketch the layout of the project.

  20. [Past and present status in the design of infant formulas].

    PubMed

    Ronayne de Ferrer, P A

    1995-12-01

    This paper describes briefly the history of infant foods, from the alternate ways of feeding developed during the late 19th century to the present-day infant formulas, and enumerates the different available types (milk-based, soy-based, hypoallergenic, lactose-free, etc,). Among the nutritional aspects the main characteristics of formulation are emphasized, especially within the nitrogen, fat and mineral fractions. Considering the nitrogen fraction, it must be taken into account that the amino acid profiles in milk-based formulas differ according to the casein/whey proteins ratio (either 80:20 or 40:60 in the so-called "adapted" or "humanized"). On the other hand, it has been recognized recently that some non-protein components of human milk, such as taurine, carnitine and nucleotides, are relevant to infant nutrition and therefore, they are being included in some formulas. Regarding fat, essential fatty acids supply is very important; present recommendations stress the importance of providing n-6 to n-3 series ratios close to that found in human milk and also a preformed supply of long-chain polyunsaturated fatty acids. Among minerals, bioavailability and relative proportions of trace elements are important issues in formulation. Other concepts of relevance are the renal solute load and the osmolarity because of their effect on neonate's metabolism.

  1. Chagas disease: Present status of pathogenic mechanisms and chemotherapy.

    PubMed

    Maya, Juan Diego; Orellana, Myriam; Ferreira, Jorge; Kemmerling, Ulrike; López-Muñoz, Rodrigo; Morello, Antonio

    2010-01-01

    There are approximately 7.8 million people in Latin America, including Chile, who suffer from Chagas disease and another 28 million who are at risk of contracting it. Chagas is caused by the flagellate protozoan Trypanosoma cruzi. It is a chronic disease, where 20%-30% of infected individuals develop severe cardiopathy, with heart failure and potentially fatal arrhythmias. Currently, Chagas disease treatment is more effective in the acute phase, but does not always produce complete parasite eradication during indeterminate and chronic phases. At present, only nifurtimox or benznidazole have been proven to be superior to new drugs being tested. Therefore, it is necessary to find alternative approaches to treatment of chronic Chagas. The current treatment may be rendered more effective by increasing the activity of anti-Chagasic drugs or by modifying the host's immune response. We have previously shown that glutathione synthesis inhibition increases nifurtimox and benznidazole activity. In addition, there is increasing evidence that cyclooxygenase inhibitors present an important effect on T. cruzi infection. Therefore, we found that aspirin reduced the intracellular infection in RAW 264.7 cells and, decreased myocarditis extension and mortality rates in mice. However, the long-term benefit of prostaglandin inhibition for Chagasic patients is still unknown.

  2. History and present status of pulmonary metastasectomy in colorectal cancer

    PubMed Central

    Treasure, Tom; Milošević, Mišel; Fiorentino, Francesca; Pfannschmidt, Joachim

    2014-01-01

    Clinical practice with respect to metastatic colorectal cancer differs from the other two most common cancers, breast and lung, in that routine surveillance is recommended with the specific intent of detecting liver and lung metastases and undertaking liver and lung resections for their removal. We trace the history of this approach to colorectal cancer by reviewing evidence for effectiveness from the 1950s to the present day. Our sources included published citation network analyses, the documented proposal for randomised trials, large systematic reviews, and meta-analysis of observational studies. The present consensus position has been adopted on the basis of a large number of observational studies but the randomised trials proposed in the 1980s and 1990s were either not done, or having been done, were not reported. Clinical opinion is the mainstay of current practice but in the absence of randomised trials there remains a possibility of selection bias. Randomised controlled trials (RCTs) are now routine before adoption of a new practice but RCTs are harder to run in evaluation of already established practice. One such trial is recruiting and shows that controlled trial are possible. PMID:25356017

  3. CRYRING@ESR: present status and future research

    NASA Astrophysics Data System (ADS)

    Lestinsky, M.; Bräuning-Demian, A.; Danared, H.; Engström, M.; Enders, W.; Fedotova, S.; Franzke, B.; Heinz, A.; Herfurth, F.; Källberg, A.; Kester, O.; Litvinov, Y.; Steck, M.; Reistad, D.; Simonsson, A.; Skeppstedt, Ö.; Stöhlker, T.; Vorobjev, G.; the CRYRING@ESR working Group

    2015-11-01

    The former storage ring CRYRING has been shipped from the Manne Siegbahn Laboratory in Stockholm to Darmstadt as a Swedish in-kind contribution to FAIR. At its new location downstream of ESR all ion species presently accessible in ESR can be transferred to CRYRING, in which ions with rigidities between 1.44 and 0.054 Tm can be stored. The original Swedish layout has been modified by reconfiguring the sequence of straight sections and by slightly increasing the circumference to ESR/2. Ions can be injected from ESR or from an independent 300 keV/u RFQ test injector. The instrumentation of the ring includes an RF drift tube system for acceleration and deceleration (1 T s-1, with a possibility for an upgrade to 7 T s-1), electron cooling, a free experimental section, and both fast and slow extraction of ions. We report on the present progress of this project, give a prospective timeline, and summarize the new research which will be enabled by this project. First beam for commissioning of the storage ring is expected for 2015, final bakeout to restore ultrahigh vacuum conditions in 2016 and ion beams injected through ESR in ˜2017.

  4. The Present Deployment Status of the MAGDAS Project

    NASA Astrophysics Data System (ADS)

    Maeda, G.; Yumoto, K.

    2012-12-01

    Since 2004, MAGDAS magnetometers have been deployed slowly but steadily throughout the world. The PI of the MAGDAS Project is Prof. K. Yumoto of the International Center for Space Weather Science and Education (Kyushu University). There are now 64 real time stations deployed throughout the world mainly in three key bands: 210 MM (Magnetic Meridian) Band, 96 MM Band, and Dip Equatorial Band. In this presentation, we summarize primarily the activities of the past 12 months for this project. This includes a new installation at Jayapura in Indonesia, and three new installations on the island of Sumatra (also Indonesia). In addition, a state-of-the-art MAGDAS 9 magnetometer was installed at Bac Lieu in the south of Vietnam.

  5. Immunotherapy for liver tumors: present status and future prospects

    PubMed Central

    Matar, Pablo; Alaniz, Laura; Rozados, Viviana; Aquino, Jorge B; Malvicini, Mariana; Atorrasagasti, Catalina; Gidekel, Manuel; Silva, Marcelo; Scharovsky, O Graciela; Mazzolini, Guillermo

    2009-01-01

    Increasing evidence suggests that immune responses are involved in the control of cancer and that the immune system can be manipulated in different ways to recognize and attack tumors. Progress in immune-based strategies has opened new therapeutic avenues using a number of techniques destined to eliminate malignant cells. In the present review, we overview current knowledge on the importance, successes and difficulties of immunotherapy in liver tumors, including preclinical data available in animal models and information from clinical trials carried out during the lasts years. This review shows that new options for the treatment of advanced liver tumors are urgently needed and that there is a ground for future advances in the field. PMID:19272130

  6. Present Status of the ILC Project and Development

    SciTech Connect

    Ross, M.; Walker, N.; Yamamoto, A.; /KEK, Tsukuba

    2011-09-01

    The Technical Design of the International Linear Collider (ILC) Project will be finished in late 2012. The Technical Design Report (TDR) will include a description of the updated design, with a cost estimate and a project plan, and the results of research and development (R & D) done in support of the ILC. Results from directed ILC R & D are used to reduce the cost and risk associated with the ILC design. We present a summary of key challenges and show how the global R & D effort has addressed them. The most important activity has been in pursuit of very high gradient superconducting RF linac technology. There has been excellent progress toward the goal of practical industrial production of niobium sheet-metal cavities with gradient performance in excess of 35 MV/m. In addition, three purpose-built beam test facilities have been constructed and used to study and demonstrate high current linac performance, electron-cloud beam dynamics and precision beam control. The report also includes a summary of component design studies and conventional facilities cost optimization design studies.

  7. [Present status and perspective of articular cartilage regeneration].

    PubMed

    Wakitani, Shigeyuki

    2007-05-01

    Because the capacity of articular cartilage for repair is limited, defects are a major clinical problem, and there is at present no satisfactory clinical technique to regenerate cartilage defects. Current clinical practice involves the bone stimulation technique, which breaks subchondral bone to facilitate cartilage repair from bone marrow derived cells and cytokines. This consists of multiple perforations, abrasions, and micro-fractures. However, with this procedure, cartilage defects are repaired with fibrocartilage, which is known to be biochemically and biomechanically different from normal hyaline cartilage and degeneration occurs in the reparative tissue. Autologous chondrocyte implantation (ACI) for repair of human articular cartilage was reported in 1994, and approved by the USA Food and Drug Association in 1997. This procedure has been performed for more than 20000 people all over the world, but its effectiveness is still controversial. Mosaic plasty was explored in the 1990s. Using this procedure, we can repair defects with hyaline cartilage, but the donor site morbidity is unsolved. To explore a new method for cartilage repair, we transplanted autologous culture-expanded bone marrow mesenchymal cells into articular cartilage defects. Clinical symptoms were improred but the repair cartilage was not hyaline cartilage. Further improvement is required. Many investigations have been made in the search for better means of repair, including gene transduction and the addition of growth factors during cell culture. In addition to bone marrow mesenchymal cells, synovial cells, adipocytes, muscle cells, etc. have been evaluated.

  8. Neuroimaging of tic genesis: Present status and future perspectives.

    PubMed

    Worbe, Yulia; Lehericy, Stephane; Hartmann, Andreas

    2015-08-01

    Tics are hyperkinetic movements that are distinctive by their variety in semiology and duration and by their ability to be modulated by cognitive control. They are the hallmark of Gilles de la Tourette syndrome. Despite the variety of clinical presentations in this syndrome, dysfunction of cortico-striato-pallido-thalamo-cortical networks is suggested as a core pathophysiological mechanism. We review recent structural and functional neuroimaging studies that focused on the anatomical substrate of tics and their possible genesis. These studies showed a consistent relationship between structural and functional abnormalities within motor cortico-basal ganglia circuits and occurrence of tics. The failure of top-down cortical control over motor pathways because of the atypical trajectory of brain development could be a possible mechanism of tic genesis. Occurrence of tics results in several adaptive mechanisms, including modification of cortico-striatal network activity (reduced functional activation of the primary motor cortex) and neurochemical (increased γ-aminobutyric acid concentrations in the supplementary motor area) and microstructural white matter pathways rearrangements.

  9. Present Status and Future Developments in Proton Therapy

    SciTech Connect

    Smith, Alfred R.

    2009-07-25

    Within the past few years, interest in proton therapy has significantly increased. This interest has been generated by a number of factors including: 1) the reporting of positive clinical results using proton beams; 2) approval of reimbursement for delivery of proton therapy; 3) the success of hospital-based proton therapy centers; and 4) the availability of modern, integrated proton therapy technology for hospital-based facilities. In the United States, this increased interest has occurred particularly at the level of smaller academic hospitals, community medical centers, and large private practices; however, interest from large academic centers continues to be strong. Particular interest exists regarding smaller and less-expensive proton therapy systems, especially the so-called 'single-room' systems. In this paper, the advantages and disadvantages of 1-room proton therapy systems will be discussed. The emphasis on smaller and cheaper proton therapy facilities has also generated interest in new proton-accelerating technologies such as superconducting cyclotrons and synchrocyclotrons, laser acceleration, and dielectric-wall accelerators. Superconducting magnets are also being developed to decrease the size and weight of isocentric gantries. Another important technical development is spot-beam scanning, which offers the ability to deliver intensity-modulated proton treatments (IMPT). IMPT has the potential to provide dose distributions that are superior to those for photon intensity modulation techniques (IMXT) and to improve clinical outcomes for patients undergoing cancer therapy. At the present time, only two facilities--one in Europe and one in the United States--have the ability to deliver IMPT treatments, however, within the next year or two several additional facilities are expected to achieve this capability.

  10. Present Status and Future Developments in Proton Therapy

    NASA Astrophysics Data System (ADS)

    Smith, Alfred R.

    2009-07-01

    Within the past few years, interest in proton therapy has significantly increased. This interest has been generated by a number of factors including: 1) the reporting of positive clinical results using proton beams; 2) approval of reimbursement for delivery of proton therapy; 3) the success of hospital-based proton therapy centers; and 4) the availability of modern, integrated proton therapy technology for hospital-based facilities. In the United States, this increased interest has occurred particularly at the level of smaller academic hospitals, community medical centers, and large private practices; however, interest from large academic centers continues to be strong. Particular interest exists regarding smaller and less-expensive proton therapy systems, especially the so-called "single-room" systems. In this paper, the advantages and disadvantages of 1-room proton therapy systems will be discussed. The emphasis on smaller and cheaper proton therapy facilities has also generated interest in new proton-accelerating technologies such as superconducting cyclotrons and synchrocyclotrons, laser acceleration, and dielectric-wall accelerators. Superconducting magnets are also being developed to decrease the size and weight of isocentric gantries. Another important technical development is spot-beam scanning, which offers the ability to deliver intensity-modulated proton treatments (IMPT). IMPT has the potential to provide dose distributions that are superior to those for photon intensity modulation techniques (IMXT) and to improve clinical outcomes for patients undergoing cancer therapy. At the present time, only two facilities—one in Europe and one in the United States—have the ability to deliver IMPT treatments, however, within the next year or two several additional facilities are expected to achieve this capability.

  11. A Window on Wikibookians: Surveying Their Statuses, Successes, Satisfactions, and Sociocultural Experiences

    ERIC Educational Resources Information Center

    Sajjapanroj, Suthiporn; Bonk, Curtis J.; Lee, Mimi Miyoung; Lin, Meng-Fen Grace

    2008-01-01

    The present study explored the experiences of 80 Wikibookians who had developed or were in the process of developing wikibooks. Both online surveys and email interviews were employed to investigate four main factors, including Wikibookian statuses, successes, satisfactions, and sociocultural experiences. The survey data indicated that the majority…

  12. CMS Tracker upgrade for HL-LHC: R&D plans, present status and perspectives

    NASA Astrophysics Data System (ADS)

    Ravera, F.

    2016-07-01

    During the high luminosity phase of the LHC (HL-LHC), the machine is expected to deliver an instantaneous luminosity of 5 ×1034cm-2s-1. A total of 3000 fb-1 of data is foreseen to be delivered, with the opening of new physics potential for the LHC experiments, but also new challenges from the point of view of both detector and electronics capabilities and radiation hardness. In order to maintain its physics reach, CMS will build a new Tracker, including a completely new Pixel Detector and Outer Tracker. The ongoing R&D activities on both pixel and strip sensors will be presented. The present status of the Inner and Outer Tracker projects will be illustrated, and the possible perspectives will be discussed.

  13. Status and Plan of the ISS-CREAM Experiment

    NASA Astrophysics Data System (ADS)

    Picot-Clemente, Nicolas; Iss-Cream Collaboration

    2016-03-01

    The Cosmic Ray Energetics and Mass (CREAM) project began as a balloon-borne experiment, which was flown successfully for 161 days in six flights over Antarctica. It was subsequently reconfigured for implementation on the International Space Station (ISS) to provide an order of magnitude increase in the exposure time with no atmospheric overburden. The ISS-CREAM instrument is configured of four subsystems: four layers of silicon charge detector (SCD) for charge measurements, top and bottom counting detectors (TCD/BCD) for electron/proton separation, a calorimeter (CAL) for energy measurements, and a boronated scintillator detector (BSD) for additional electron/proton distinction. CREAM is designed to investigate cosmic-ray origin, acceleration, and propagation by directly measuring individual particles with energy between 1012-1015eV and determining cosmic ray composition from protons to iron. The hardware was successfully tested, and remote monitoring and control capabilities were verified. It is scheduled for launch in 2016. The status and plan of the ISS-CREAM experiment will be presented.

  14. Status of U.S. FCEV and Infrastructure Learning Demonstration Project (Presentation)

    SciTech Connect

    Wipke, K.; Sprik, S.; Kurtz, J.; Ramsden, T.; Ainscough, C.; Saur, G.

    2011-03-01

    Presented at the Japan Hydrogen and Fuel Cell Demonstration Project (JHFC), 1 March 2011, Tokyo, Japan. This presentation summarizes the status of U.S. fuel cell electric vehicles and infrastructure learning demonstration project.

  15. Boerhaave's syndrome: Experience with patients presenting later than 24 hours.

    PubMed

    Ganguly, Amit; Porwal, Manish; Khandeparkar, Jagdish

    2015-01-01

    Boerhaave's syndrome is the most sinister cause of esophageal perforation. Clinical presentation is vague. Diagnostic delays are frequent. As condition is rare therefore no consensus exists on management. A wide variety of management options are described in literature, each with its advantages and disadvantages. We present our experience of managing these cases which presented after 24 hr. Of onset of symptoms with emphasis on primary reinforced repair as first line surgical option. PMID:27522739

  16. The Mirror Fusion Test Facility cryogenic system: Performance, management approach, and present equipment status

    SciTech Connect

    Slack, D.S.; Chronis, W.C.

    1987-06-08

    The cryogenic system for the Mirror Fusion Test Facility (MFTF) is a 14-kW, 4.35-K helium refrigeration system that proved to be highly successful and cost-effective. All operating objectives were met, while remaining within a few percent of initial cost and schedule plans. The management approach used in MFTF allowed decisions to be made quickly and effectively, and it helped keep costs down. Manpower levels, extent and type of industrial participation, key aspects of subcontractor specifications, and subcontractor interactions are reviewed, as well as highlights of the system tests, operation, and present equipment status. Organizations planning large, high-technology systems may benefit from this experience with the MFTF cryogenic system.

  17. Ioffe Institute GRB experiments: past, present and future

    NASA Astrophysics Data System (ADS)

    Aptekar, R. L.; Golenetskii, S. V.; Frederiks, D. D.; Mazets, E. P.; Palshin, V. D.

    2013-07-01

    The short review of GRB studies performed for many years by Ioffe Institute is presented. An important breakthrough in GRB studies became possible owing to four Konus experiments carried out by the Ioffe Institute onboard the Venera 11 to 14 interplanetary missions from 1978 to 1983. The joint Russian-American Konus-Wind experiment, which has already been operating for more than 18 years, provides important and often unique data regarding GRB characteristics in 20 keV - 15 MeV energy range. These investigations were complemented by several Konus and Helicon experiments onboard Russian near-Earth spacecraft. A short description of future Konus-UF and Konus-M experiments are also given.

  18. The Status and Recent Results of the Telescope Array Experiment

    NASA Astrophysics Data System (ADS)

    Yamazaki, Katsuya

    The Telescope Array (TA) is a cosmic ray observatory of the largest aperture in the northern hemisphere, located in a desert in the western part of Utah, U.S.A., to explore the origin of ultrahigh energy cosmic rays, photons, and neutrinos. The TA employs two types of detectors to observe air showers generated by cosmic rays in the atmosphere: the first is a "surface detector (SD)" of scintillation counters to measure shower particles on the ground, and the second is a "fluorescence detector (FD)" of telescopes installed in three stations to observe fluorescence light, caused by air shower particles, from the atmosphere above the SD array. The TA detectors have been in routine operation since May 2008. We measured the energy spectrum of cosmic rays with energy greater than 1018 eV from our first 4-year data. We found a clear suppression of comic ray intensity above 5 × 1019 eV. This feature is consistent with a theoretical prediction that cosmic rays lose energies due to interaction with cosmic microwave background photons during propagation in the intergalactic space. In this talk, We will present the status of the TA experiment and the recent results, including the energy spectrum, study of the primary mass composition, and searches for anisotropies in the arrival directions. We also briefly describe plans for further extensions.

  19. Heterosexual experience, marital status, and orientation of homosexual males.

    PubMed

    McConaghy, N

    1978-11-01

    The penile volume responses of homosexual males to pictures of nude women and men were measured and related to the subjects' marital status and experience of heterosexual intercourse. Single subjects with no experience of heterosexual intercourse and married subjects with a history of intercourse with only their wives showed significantly greater response to pictures of men compared to pictures of women than did single subjects with experience of heterosexual intercourse and married subjects with experience of intercourse with women additional to their wives. It was concluded that extensive experience of heterosexual intercourse with one partner did not reduce homosexual responsiveness as measured by subjects' penile response to pictures of nude men and women. It was further concluded that some homosexual males showed physiological evidence of a degree of bisexuality in addition to the behavioral evidence that they sought heterosexual physical relationships.

  20. Present status of the NIJI-IV storage-ring free-electron lasers

    SciTech Connect

    Yamazaki, T.; Yamada, K.; Sei, N.

    1995-12-31

    The tunable region of the free-electron-laser (FEL) wavelength with the NIJI-IV system is now 348{approximately}595 nm. After the lasing at 352 nm in 1994, the quality of the electron beam stored in the ring has been improved further, and the highest peak intensity of the laser obtained so far is more than 300 times as high as that of the resonated spontaneous emission. The macro-temporal structure of the lasing has been greatly improved. Recently, a single-bunch injection system was completed, and the system has been installed in the injector linac, which is expected to increase the peak stored-beam current. The commissioning and the test of the new system is under way. The beam transporting system from the linac to the ring is also being modified by increasing the number of quadrupole magnets. The experiments related to the FEL in the ultraviolet wavelength region will be begun in this coming May. The results and the status of the FEL experiments will be presented at the Conference.

  1. Present Status and Future Prospects of Laser Fusion and Related High Energy Density Plasma Research

    NASA Astrophysics Data System (ADS)

    Mima, Kunioki

    2004-12-01

    The present status and future prospects of the laser fusion research and related laser plasma physics are reviewed. In laser fusion research, giant lasers for ignition and burn by imploding DT fuel pellets are under construction at LLNL (Lawrence Livermore National Laboratory) and CEA, France. In Japan , the Gekko XII and the Peta Watt laser system have been operated to investigate the implosion hydrodynamics, fast ignition, and the relativistic laser plasma interactions and a new project; FIREX( Fast Ignition Realization Experiment) had started toward the ignition and burn at the Institute of laser Engineering of Osaka University. Recently, heating experiments with cone shell target have been carried out. The thermal neutron yield is found to increase by three orders of magnitude by the peta watt laser injection to the cone shell target. The FIREX-I is planned according to this experimental results, where multi 10kJ peta watt laser is used to heat compressed DT fuel to the ignition temperature. The FIREX-II will follow for demonstrating ignition and burn, in which the implosion laser and heating laser are up-graded.

  2. Presentations of self and the status dynamics of psychotherapy and supervision.

    PubMed

    Schwartz, Wynn

    2008-01-01

    This article explores basic issues in the status dynamics of psychotherapy and supervision. Self-presentation and status markers create a dynamic that affects the participants in psychotherapy and in its supervision. "Political correctness" at times, makes it difficult for trainees to discuss their feelings and observations about status differences with their supervisors. One of the roles of supervision is the rite of passage, involving moving the trainee from the world of nonpsychologist to membership in the community of psychologists. During supervision, the supervisor's self-disclosure of relevant autobiographical details and problematic thoughts and feeling is recommended as useful, even though such revelations in psychotherapy practice might be inappropriate or hazardous.

  3. Perceived Social Status and Learning Experiences in Social Cognitive Career Theory

    ERIC Educational Resources Information Center

    Thompson, Mindi N.; Dahling, Jason J.

    2012-01-01

    The purpose of this study was to test a model based on Social Cognitive Career Theory (Lent, Brown, & Hackett, 1994) that placed perceived social status as an antecedent of career-related learning experiences, self-efficacy, and outcome expectations. Gender was included in the present model and results indicated that gender related as expected to…

  4. Present status and future directions of the Mayo/IBM PACS project

    NASA Astrophysics Data System (ADS)

    Morin, Richard L.; Forbes, Glenn S.; Gehring, Dale G.; Salutz, James R.; Pavlicek, William

    1991-07-01

    This joint project began in 1988 and was motivated by the need to develop an alternative to the archival process in place at that time (magnetic tape) for magnetic resonance imaging and neurological computed tomography. In addition, this project was felt to be an important step in gaining the necessary clinical experience for the future implementation of various aspects of electronic imaging. The initial phase of the project was conceived and developed to prove the concept, test the fundamental components, and produce performance measurements for future work. The key functions of this phase centered on attachment of imaging equipment (GE Signa) and archival processes using a non-dedicated (institutionally supplied) local area network (LAN). Attachment of imaging equipment to the LAN was performed using commercially available devices (Ethernet, PS/2, Token Ring). Image data were converted to ACR/NEMA format with retention of the vendor specific header information. Performance measurements were encouraging and led to the design of following projects. The second phase has recently been concluded. The major features of this phase have been to greatly expand the network, put the network into clinical use, establish an efficient and useful viewing station, include diagnostic reports in the archive data, provide wide area network (WAN) capability via ISDN, and establish two-way real-time video between remote sites. This phase has heightened both departmental and institutional thought regarding various issues raised by electronic imaging. Much discussion regarding both present as well as future archival processes has occurred. The use of institutional LAN resources has proven to be adequate for the archival function examined thus far. Experiments to date have shown that use of dedicated resources will be necessary for retrieval activities at even a basic level. This report presents an overview of the background present status and future directions of the project.

  5. Status of RAISE, the Rapid Acquisition Imaging Spectrograph Experiment

    NASA Astrophysics Data System (ADS)

    Laurent, Glenn T.; Hassler, D. M.; DeForest, C.; Ayres, T. R.; Davis, M.; De Pontieu, B.; Schuehle, U.; Warren, H.

    2013-07-01

    The Rapid Acquisition Imaging Spectrograph Experiment (RAISE) sounding rocket payload is a high speed scanning-slit imaging spectrograph designed to observe the dynamics and heating of the solar chromosphere and corona on time scales as short as 100 ms, with 1 arcsec spatial resolution and a velocity sensitivity of 1-2 km/s. The instrument is based on a new class of UV/EUV imaging spectrometers that use only two reflections to provide quasi-stigmatic performance simultaneously over multiple wavelengths and spatial fields. The design uses an off-axis parabolic telescope mirror to form a real image of the sun on the spectrometer entrance aperture. A slit then selects a portion of the solar image, passing its light onto a near-normal incidence toroidal grating, which re-images the spectrally dispersed radiation onto two array detectors. Two full spectral passbands over the same one-dimensional spatial field are recorded simultaneously with no scanning of the detectors or grating. The two different spectral bands (1st-order 1205-1243Å and 1526-1564Å) are imaged onto two intensified Active Pixel Sensor (APS) detectors whose focal planes are individually adjusted for optimized performance. The telescope and grating are coated with B4C to enhance short wavelength (2nd order) reflectance, enabling the instrument to record the brightest lines between 602-622Å and 761-780Å at the same time. RAISE reads out the full field of both detectors at 5-10 Hz, allowing us to record over 1,500 complete spectral observations in a single 5-minute rocket flight, opening up a new domain of high time resolution spectral imaging and spectroscopy. We present an overview of the project, a summary of the maiden flight results, and an update on instrument status.Abstract (2,250 Maximum Characters): The Rapid Acquisition Imaging Spectrograph Experiment (RAISE) sounding rocket payload is a high speed scanning-slit imaging spectrograph designed to observe the dynamics and heating of the solar

  6. The current status of orbital experiments for UHECR studies

    NASA Astrophysics Data System (ADS)

    Panasyuk, M. I.; Casolino, M.; Garipov, G. K.; Ebisuzaki, T.; Gorodetzky, P.; Khrenov, B. A.; Klimov, P. A.; Morozenko, V. S.; Sakaki, N.; Saprykin, O. A.; Sharakin, S. A.; Takizawa, Y.; Tkachev, L. G.; Yashin, I. V.; Zotov, M. Yu

    2015-08-01

    Two types of orbital detectors of extreme energy cosmic rays are being developed nowadays: (i) TUS and KLYPVE with reflecting optical systems (mirrors) and (ii) JEM-EUSO with high- transmittance Fresnel lenses. They will cover much larger areas than existing ground-based arrays and almost uniformly monitor the celestial sphere. The TUS detector is the pioneering mission developed in SINP MSU in cooperation with several Russian and foreign institutions. It has relatively small field of view (±4.5°), which corresponds to a ground area of 6.4 • 103 km2. The telescope consists of a Fresnel-type mirror-concentrator (∼ 2 m2) and a photo receiver (a matrix of 16 x 16 photomultiplier tubes). It is to be deployed on the Lomonosov satellite, and is currently at the final stage of preflight tests. Recently, SINP MSU began the KLYPVE project to be installed on board of the Russian segment of the ISS. The optical system of this detector contains a larger primary mirror (10 m2), which allows decreasing the energy threshold. The total effective field of view will be at least ±14° to exceed the annual exposure of the existing ground-based experiments. Several configurations of the detector are being currently considered. Finally, JEM-EUSO is a wide field of view (±30°) detector. The optics is composed of two curved double-sided Fresnel lenses with 2.65 m external diameter, a precision diffractive middle lens and a pupil. The ultraviolet photons are focused onto the focal surface, which consists of nearly 5000 multi-anode photomultipliers. It is developed by a large international collaboration. All three orbital detectors have multi-purpose character due to continuous monitoring of various atmospheric phenomena. The present status of development of the TUS and KLYPVE missions is reported, and a brief comparison of the projects with JEM-EUSO is given.

  7. RAISE (Rapid Acquisition Imaging Spectrograph Experiment): Results and Instrument Status

    NASA Astrophysics Data System (ADS)

    Laurent, Glenn T.; Hassler, Donald; DeForest, Craig; Ayres, Tom; Davis, Michael; DePontieu, Bart; Diller, Jed; Graham, Roy; Schule, Udo; Warren, Harry

    2015-04-01

    We present initial results from the successful November 2014 launch of the RAISE (Rapid Acquisition Imaging Spectrograph Experiment) sounding rocket program, including intensity maps, high-speed spectroheliograms and dopplergrams, as well as an update on instrument status. The RAISE sounding rocket payload is the fastest high-speed scanning-slit imaging spectrograph flown to date and is designed to observe the dynamics and heating of the solar chromosphere and corona on time scales as short as 100-200ms, with arcsecond spatial resolution and a velocity sensitivity of 1-2 km/s. The instrument is based on a class of UV/EUV imaging spectrometers that use only two reflections to provide quasi-stigmatic performance simultaneously over multiple wavelengths and spatial fields. The design uses an off-axis parabolic telescope mirror to form a real image of the sun on the spectrometer entrance aperture. A slit then selects a portion of the solar image, passing its light onto a near-normal incidence toroidal grating, which re-images the spectrally dispersed radiation onto two array detectors. Two full spectral passbands over the same one-dimensional spatial field are recorded simultaneously with no scanning of the detectors or grating. The two different spectral bands (1st-order 1205-1243Å and 1526-1564Å) are imaged onto two intensified Active Pixel Sensor (APS) detectors whose focal planes are individually adjusted for optimized performance. RAISE reads out the full field of both detectors at 5-10 Hz, allowing us to record over 1,500 complete spectral observations in a single 5-minute rocket flight, opening up a new domain of high time resolution spectral imaging and spectroscopy. RAISE is designed to study small-scale multithermal dynamics in active region (AR) loops, explore the strength, spectrum and location of high frequency waves in the solar atmosphere, and investigate the nature of transient brightenings in the chromospheric network.

  8. DESIGN AND STATUS OF THE VISA II EXPERIMENT.

    SciTech Connect

    ANDONIAN,G.BABZIEN,MLBEN-ZVI,I.YAKIMENKO,Y.ET AL.

    2004-03-24

    VISA II is the follow-up project to the successful Visible to Infrared SASE Amplifier (VISA) experiment at the Accelerator Test Facility (ATF) in Brookhaven National Lab (BNL). This paper will report the motivation for and status of the two main experiments associated with the VISA II program. One goal of VISA II is to perform an experimental study of the physics of a chirped beam SASE FEL at the upgraded facilities of the ATF. This requires a linearization of the transport line to preserve energy chirping of the electron beam at injection. The other planned project is a strong bunch compression experiment, where the electron bunch is compressed in the chicane, and the dispersive beamline transport, allowing studies of deep saturation.

  9. Status of the AFP project in the ATLAS experiment

    NASA Astrophysics Data System (ADS)

    Taševský, Marek

    2015-04-01

    Status of the AFP project in the ATLAS experiment is summarized. The AFP system is composed of a tracker to detect intact, diffractively scattered protons, and of a time-of-flight detector serving to suppress background from pile-up interactions. The whole system, located around 210 m from the main ATLAS detector, is placed in Roman Pots which move detectors from and to the incident proton beams. A typical distance of the closest approach of the tracker to these beams is 2-3 mm. The main physics motivation lies in measuring diffractive processes in runs with not a very high amount of pile-up.

  10. Status of Theory and Experiment in Hadronic Parity Violation

    NASA Astrophysics Data System (ADS)

    Snow, W. M.; Ahmed, M. W.; Bowman, J. D.; Crawford, C.; Fomin, N.; Gao, H.; Gericke, M. T.; Gudkov, V.; Holstein, B. R.; Howell, C. R.; Huffman, P.; van Oers, W. T. H.; Penttilä, S.; Wu, Y. K.

    2016-02-01

    Hadronic parity violation uses quark-quark weak interactions to probe nonperturbative strong interaction dynamics through two nonperturbative QCD scales: ΛQCD and the fine-tuned MeV scales of NN bound states in low energy nuclear physics. The current and projected availability of high-intensity neutron and photon sources coupled with ongoing experiments and continuing developments in theoretical methods provide the opportunity to greatly expand our understanding of hadronic parity violation in few-nucleon systems. The current status of these efforts and future plans are discussed.

  11. Status of the AFP project in the ATLAS experiment

    SciTech Connect

    Taševský, Marek

    2015-04-10

    Status of the AFP project in the ATLAS experiment is summarized. The AFP system is composed of a tracker to detect intact, diffractively scattered protons, and of a time-of-flight detector serving to suppress background from pile-up interactions. The whole system, located around 210 m from the main ATLAS detector, is placed in Roman Pots which move detectors from and to the incident proton beams. A typical distance of the closest approach of the tracker to these beams is 2–3 mm. The main physics motivation lies in measuring diffractive processes in runs with not a very high amount of pile-up.

  12. Status of SRNL radiological field lysimeter experiment-Year 1

    SciTech Connect

    Kaplan, D.; Roberts, K.; Bagwell, L.

    2013-10-01

    The Savannah River National Laboratory (SRNL) Radiological Field Lysimeter Experiment is a one-of-a-kind field facility designed to study radionuclide geochemical processes at a larger spatial scale (from grams to tens of kilograms sediment) and temporal scale (from months to 10 years) than is readily afforded through laboratory studies. The lysimeter facility is intended to capture the natural heterogeneity of moisture and temperature regimes in the vadose zone, the unsaturated subsurface region between the surface soil and the underlying aquifer. The 48 lysimeter columns, which contain various radionuclides (and stable iodine), were opened to rainfall infiltration on July 5, 2012. The objective of this report is to provide a status of the lysimeter facility operations and to compile data collected during FY13, including leachate volume, rainfall, and soil moisture and temperature in situ probe data. Radiological leachate data are not presented in this document but will be the subject of a separate document.1 Leachate samples were collected quarterly and shipped to Clemson University for radiological analyses. Rainfall, leachate volume, moisture and temperature probe data were collected continuously. During operations of the facility this year, there were four safety or technical concerns that required additional maintenance: 1) radioactivity was detected in one of the overflow bottles (captured water collected from the secondary containment that does not come in contact with the radiological source material); 2) rainwater accumulated within the sample-bottle storage sheds; 3) overflow containers collected more liquid than anticipated; and 4) significant spider infestation occurred in the sample-bottle storage sheds. To address the first three concerns, each of the lysimeter columns was re-plumbed to improve and to minimize the number of joint unions. To address the fourth concern regarding spiders, new sample-bottle water sheds were purchased and a pest control

  13. Nonconvulsive status epilepticus precipitated by carbamazepine presenting as dissociative and affective disorders in adolescents.

    PubMed

    Marini, Carla; Parmeggiani, Lucio; Masi, Gabriele; D'Arcangelo, Gianluca; Guerrini, Renzo

    2005-08-01

    Nonconvulsive status epilepticus can be confused with psychiatric disorders. Inappropriate drug treatment can represent a precipitating factor. We describe two patients with idiopathic generalized epilepsy in whom nonconvulsive status epilepticus, aggravated by carbamazepine, was misdiagnosed as psychiatric disorder. A 14-year-old girl experienced a tonic-clonic seizure at age 12 years preceded by monthly episodes of confusion with awkward behavior since age 9 years. She was treated with carbamazepine, and the episodes of confusion became more frequent, leading to a diagnosis of dissociative disorder. An electroencephalogram during one of these episodes revealed nonconvulsive status epilepticus. Substitution of carbamazepine with valproic acid controlled the episodes of status epilepticus. A 23-year-old woman presented at age 16 years with a tonic-clonic seizure. Since early adolescence, she had had episodes of depressive mood, worsening of school performances, and facial tics. Carbamazepine treatment caused worsening of the depressive episodes and facial tics. An electroencephalogram during a typical episode revealed nonconvulsive status epilepticus. Carbamazepine substitution with valproate led to seizure freedom and behavioral improvement. Nonconvulsive status epilepticus should be suspected and searched for in patients with epileptic seizures and ictal or fluctuating behavioral disorders.

  14. STATUS OF THE INTERNATIONAL MUON IONIZATION COOLING EXPERIMENT(MICE)

    SciTech Connect

    Zisman, Michael S.

    2007-07-18

    An international experiment to demonstrate muon ionization cooling is scheduled for beam at Rutherford Appleton Laboratory (RAL) in 2007. The experiment comprises one cell of the Study II cooling channel [1], along with upstream and downstream detectors to identify individual muons and measure their initial and final 6D phase-space parameters to a precision of 0.1%. Magnetic design of the beam line and cooling channel are complete and portions are under construction. The experiment will be described, including cooling channel hardware designs, fabrication status, and running plans. Phase 1 of the experiment will prepare the beam line and provide detector systems, including time-of-flight, Cherenkov, scintillating-fiber trackers and their spectrometer solenoids, and an electromagnetic calorimeter. The Phase 2 system will add the cooling channel components, including liquid-hydrogen absorbers embedded in superconducting Focus Coil solenoids, 201-MHz normal-conducting RF cavities, and their surrounding Coupling Coil solenoids. The MICE Collaboration goal is to complete the experiment by 2010; progress toward this is discussed.

  15. Status of Magnetic Nozzle and Plasma Detachment Experiment

    SciTech Connect

    Chavers, D. Gregory; Dobson, Chris; Jones, Jonathan; Lee, Michael; Martin, Adam; Gregory, Judith; Cecil, Jim; Bengtson, Roger D.; Breizman, Boris; Arefiev, Alexey; Chang-Diaz, Franklin; Squire, Jared; Glover, Tim; McCaskill, Greg; Cassibry, Jason; Li Zhongmin

    2006-01-20

    High power plasma propulsion can move large payloads for orbit transfer, lunar missions, and beyond with large savings in fuel consumption owing to the high specific impulse. At high power, lifetime of the thruster becomes an issue. Electrodeless devices with magnetically guided plasma offer the advantage of long life since magnetic fields confine the plasma radially and keep it from impacting the material surfaces. For decades, concerns have been raised about the plasma remaining attached to the magnetic field and returning to the vehicle along the closed magnetic field lines. Recent analysis suggests that this may not be an issue if the magnetic field is properly shaped in the nozzle region and the plasma has sufficient energy density to stretch the magnetic field downstream. An experiment is being performed to test the theory regarding the MHD detachment scenario. The status of that experiment will be discussed in this paper.

  16. Design and status of the Mu2e experiment

    NASA Astrophysics Data System (ADS)

    Miscetti, Stefano

    2016-04-01

    The Mu2e experiment aims to measure the charged-lepton flavor violating neutrino-less conversion of a negative muon into an electron in the field of an aluminum nucleus. The objective is to improve the previous measurement by four orders of magnitude with the use of a similar technique. For the conversion process, the signal will appear as a mono-energetic electron very close to the muon rest mass. In the Standard Model these process have negligible rates. However, in many Beyond the Standard Model scenarios their rates are within the reach of next generation experiments. In this paper, we explain the sensitivity to new physics scale and the complementarity of approach and reach provided by MU2E with respect to Mu3e and MEG upgrade. Mu2e experimental technique, design and status will be the focus of this paper.

  17. Present Status and Future Plans of the SR Center in Ritsumeikan University

    SciTech Connect

    Ohta, Toshiaki

    2007-03-30

    The SR center has been actively used in Ritsumeikan University for synchrotron radiation basic researches, education and training of graduate students and industrial applications for more than ten years. Present status of the storage ring and some recent activities are introduced. Future prospects are also addressed.

  18. United States National Hydrogen Fuel Cell Vehicle and Infrastructure Learning Demonstration - Status and Results (Presentation)

    SciTech Connect

    Wipke,K.; Sprik, S.; Kurtz, J.; Ramsden, T.; Garbak, J.

    2009-03-06

    This presentation provides status and results for the United States National Hydrogen Fuel Cell Vehicle Learning Demonstration, including project objectives, partners, the National Renewable Energy Laboratory's role in the project and methodology, how to access complete results, and results of vehicle and infrastructure analysis.

  19. The Martian Radiation Environment Experiment -- Results and Status

    NASA Astrophysics Data System (ADS)

    Zeitlin, C.; Cleghorn, T. F.; Cucinotta, F. A.; Saganti, P.; Andersen, V.; Lee, K. T.; Pinsky, L. S.; Atwell, W.; Turner, R.

    2004-05-01

    Ionizing radiation in space presents a potentially serious health hazard to astronauts on long-duration missions. Missions that take humans outside the geomagnetosphere (which provides significant shielding for crews in low-Earth orbit) are of particular concern. A mission to Mars would expose a crew to a substantial radiation dose from high-energy heavy ions in the Galactic Cosmic Radiation (GCR). Though not expected to cause acute effects, such exposures might endanger the long-term health of crewmembers, leading to increased risk of late effects such as cancer and cataract. Since the biological effects of these ions are not well understood, NASA cannot yet specify career limits for deep-space missions. While ground-based research in radiobiology continues, it is necessary to characterize the radiation field on the Martian surface. This is determined by the radiation incident on the top of the Martian atmosphere, the transmission properties of the atmosphere, and the production of secondary particles (neutrons in particular) in the upper part of the surface. The Martian Radiation Environment Experiment (MARIE), aboard the 2001 Mars Odyssey spacecraft, has returned the first detailed measurements of the radiation field incident on the atmosphere. MARIE consists of a stack of silicon charged-particle detectors, designed to measure the nearly-constant flux of energetic Galactic Cosmic Rays (GCR) and intermittent Solar Particle Events (SPE). The detector is optimized for the detection of solar protons and helium in the energy range from 30 to 75 MeV/nucleon, though higher energies and heavier ions are also detected. Despite considerable uncertainties in data normalization, the measured dose agrees with model calculations, to an accuracy well within the (conservatively) estimated errors. As of this writing (Feb. 2004), MARIE is off, having sustained damage during the large Solar Particle Event of Oct. 29, 2003. Attempts to recover the instrument will resume in the

  20. Status of the International Muon Ionization Cooling Experiment (MICE)

    SciTech Connect

    Zisman, Michael S.; Zisman, Michael S.

    2007-02-02

    An international experiment to demonstrate muonionization cooling is scheduled for beam at RutherfordAppleton Laboratory (RAL) in 2007. The experimentcomprises one cell of the Study II cooling channel [1],along with upstream and downstream detectors to identifyindividual muons and measure their initial and final 6Dphase-space parameters to a precision of 0.1percent. Magneticdesign of the beam line and cooling channel are completeand portions are under construction. The experiment willbe described, including cooling channel hardware designs,fabrication status, and running plans. Phase 1 of theexperiment will prepare the beam line and providedetector systems, including time-of-flight, Cherenkov,scintillating-fiber trackers and their spectrometersolenoids, and an electromagnetic calorimeter. The Phase2 system will add the cooling channel components,including liquid-hydrogen absorbers embedded insuperconducting Focus Coil solenoids, 201-MHz normalconductingRF cavities, and their surrounding CouplingCoil solenoids. The MICE Collaboration goal is tocomplete the experiment by 2010; progress toward this isdiscussed.

  1. Status of Proof-of-principle Experiment for Coherent Electron Cooling

    SciTech Connect

    Pinayev, I; Ben-Zvi, I; Bengtsson, J; Elizarov, A; Fedotov, A V; Gassner, D M; Hao, Y; Kayran, D; Litvinenko, V; Mahler, G J; Meng, W; Roser, T; Sheehy, B; Than, R; Tuozzolo, J E; Wang, G; Webb, S D; Yakimenko, V; Bell, G I; Bruhwiler, D L; Ranjbar, V H; Schwartz, B T; Hutton, A; Krafft, G A; Poelker, M; Rimmer, R A; Kholopov, M A; Vobly, P

    2012-07-01

    Coherent electron cooling (CEC) has a potential to significantly boost luminosity of high-energy, high-intensity hadron colliders. To verify the concept we conduct proof-of-the-principle experiment at RHIC. In this paper, we describe the current experimental setup to be installed into 2 o'clock RHIC interaction regions. We present current design, status of equipment acquisition and estimates for the expected beam parameters.

  2. Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

    PubMed Central

    Onakpoya, Oluwatoyin Helen; Adeoti, Caroline Olufunlayo; Oluleye, Tunji Sunday; Ajayi, Iyiade Adeseye; Majengbasan, Timothy; Olorundare, Olayemi Kolawole

    2016-01-01

    Background To review the visual status and clinical presentation of patients with retinitis pigmentosa (RP). Methodology Multicenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization’s visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0.05. Results One hundred and ninety-two eyes of 96 patients with mean age of 39.08±18.5 years and mode of 25 years constituted the study population; 55 (57.3%) were males and 41 (42.7%) females. Loss of vision 67 (69.8%) and night blindness 56 (58.3%) were the leading symptoms. Twenty-one (21.9%) patients had a positive family history, with RP present in their siblings 15 (71.4%), grandparents 11 (52.3%), and parents 4 (19.4%). Forty (41.7%) were blind at presentation and 23 (24%) were visually impaired. Blindness in six (15%) patients was secondary to glaucoma. Retinal vascular narrowing and retinal pigmentary changes of varying severity were present in all patients. Thirty-five (36.5%) had maculopathy, 36 (37.5%) refractive error, 19 (20%) lenticular opacities, and eleven (11.5%) had glaucoma. RP was typical in 85 patients (88.5%). Older patients had higher rates of blindness at presentation (P=0.005); blindness and visual impairment rate at presentation were higher in males than females (P=0.029). Conclusion Clinical presentation with advanced diseases, higher blindness rate in older patients, sex-related difference in blindness/visual impairment rates, as well as high glaucoma blindness in RP patients requires urgent attention in southwestern Nigeria.

  3. Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

    PubMed Central

    Onakpoya, Oluwatoyin Helen; Adeoti, Caroline Olufunlayo; Oluleye, Tunji Sunday; Ajayi, Iyiade Adeseye; Majengbasan, Timothy; Olorundare, Olayemi Kolawole

    2016-01-01

    Background To review the visual status and clinical presentation of patients with retinitis pigmentosa (RP). Methodology Multicenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization’s visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0.05. Results One hundred and ninety-two eyes of 96 patients with mean age of 39.08±18.5 years and mode of 25 years constituted the study population; 55 (57.3%) were males and 41 (42.7%) females. Loss of vision 67 (69.8%) and night blindness 56 (58.3%) were the leading symptoms. Twenty-one (21.9%) patients had a positive family history, with RP present in their siblings 15 (71.4%), grandparents 11 (52.3%), and parents 4 (19.4%). Forty (41.7%) were blind at presentation and 23 (24%) were visually impaired. Blindness in six (15%) patients was secondary to glaucoma. Retinal vascular narrowing and retinal pigmentary changes of varying severity were present in all patients. Thirty-five (36.5%) had maculopathy, 36 (37.5%) refractive error, 19 (20%) lenticular opacities, and eleven (11.5%) had glaucoma. RP was typical in 85 patients (88.5%). Older patients had higher rates of blindness at presentation (P=0.005); blindness and visual impairment rate at presentation were higher in males than females (P=0.029). Conclusion Clinical presentation with advanced diseases, higher blindness rate in older patients, sex-related difference in blindness/visual impairment rates, as well as high glaucoma blindness in RP patients requires urgent attention in southwestern Nigeria. PMID:27601870

  4. The library system of the DFVLR: Present status, planned reorganization, user possibilities

    NASA Technical Reports Server (NTRS)

    Sternemann, P.

    1985-01-01

    This paper gives an overview of the present status, planned alterations, and the scope of users of the DFVLR library, as well as a survey of library related activities outside of the library department. Attention is given to the tasks of the DFVLR which include research, assistance in planning and carrying out projects, and the construction and operation of large test installations, showing how they relate to demands on the library.

  5. Advanced Test Reactor Testing Experience: Past, Present and Future

    SciTech Connect

    Frances M. Marshall

    2005-04-01

    The Advanced Test Reactor (ATR), at the Idaho National Laboratory (INL), is one of the world’s premier test reactors for providing the capability for studying the effects of intense neutron and gamma radiation on reactor materials and fuels. The physical configuration of the ATR, a 4-leaf clover shape, allows the reactor to be operated at different power levels in the corner “lobes” to allow for different testing conditions for multiple simultaneous experiments. The combination of high flux (maximum thermal neutron fluxes of 1E15 neutrons per square centimeter per second and maximum fast [E>1.0 MeV] neutron fluxes of 5E14 neutrons per square centimeter per second) and large test volumes (up to 48" long and 5.0" diameter) provide unique testing opportunities. The current experiments in the ATR are for a variety of test sponsors -- US government, foreign governments, private researchers, and commercial companies needing neutron irradiation services. There are three basic types of test configurations in the ATR. The simplest configuration is the sealed static capsule, wherein the target material is placed in a capsule, or plate form, and the capsule is in direct contact with the primary coolant. The next level of complexity of an experiment is an instrumented lead experiment, which allows for active monitoring and control of experiment conditions during the irradiation. The highest level of complexity of experiment is the pressurized water loop experiment, in which the test sample can be subjected to the exact environment of a pressurized water reactor. For future research, some ATR modifications and enhancements are currently planned. This paper provides more details on some of the ATR capabilities, key design features, experiments, and future plans.

  6. New Onset Refractory Status Epilepticus as an Unusual Presentation of a Suspected Organophosphate Poisoning

    PubMed Central

    Waheed, Shahan; Sabeen, Amber; Ullah Khan, Nadeem

    2014-01-01

    New onset refractory status epilepticus (NORSE) is a new entity in medical literature. It has different infectious and noninfectious etiologies showing a devastating impact onto the clinical outcome of patients. Therapy with anaesthetic and antiepileptic agents often fails to improve the condition, unless the primary cause is rectified. Here is presented the case of a young female with a history of depression who after a recent bereavement came to the Emergency Department of Aga Khan University Hospital with complaints of drowsiness that lasted for few hours. Though she had no history of organophosphate poisoning, her physical examination and further investigations were suggestive of the diagnosis. During her hospital stay, she developed refractory status epilepticus. Her seizures did not respond to standard antiepileptic and intravenous anesthetic agents and subsided only after intravenous infusion of atropine for a few days. Organophosphate poisoning is a very common presentation in the developing world and the associated status epilepticus poses a devastating problem for emergency physicians. In patients with suspected organophosphate poisoning with favoring clinical exam findings, the continuation of atropine intravenous infusion can be a safe option to abate seizures. PMID:25580311

  7. Status and Prospects of the Muonium Experiment at J-Parc

    NASA Astrophysics Data System (ADS)

    Torii, H. A.; Tanaka, K. S.; Tajima, M.; Mizutani, T.; Matsuda, Y.; Fukao, Y.; Iinuma, H.; Ikedo, Y.; Kadono, R.; Kawamura, N.; Koda, A.; Kojima, K.; Mibe, T.; Miyake, Y.; Nagamine, K.; Nishiyama, K.; Ohkubo, R.; Ogitsu, T.; Saito, N.; Sasaki, K.; Shimomura, K.; Strasser, P.; Sugano, M.; Toyoda, A.; Ueno, K.; Yamamoto, A.; Yoshida, M.; Ishida, K.; Iwasaki, M.; Kamigaito, O.; Kanda, S.; Tomono, D.; Ueno, Y.; Kubo, K.; Aoki, M.; Torikai, E.; Kawall, D.

    2014-12-01

    A microwave spectroscopy experiment of muonium atoms are being prepared at J-PARC in Japan, aiming at an improved relative precision at a level of 10-8 in determination of the muonic magnetic moment. A major improvement of statistical uncertainty is due to higher muon intensity of the pulsed beam at J-PARC, while further improvements are expected for systematic uncertainties. Reduction of sources of systematic uncertainties are being studied: those arising from microwave power fluctuations, magnetic field inhomogeneity, muon stopping distribution and gas-density shift of resonance frequencies. Status and prospects of studies and developments of the experiment is presented in this paper.

  8. Overview, Status, and Plans of the Plasma Liner Experiment (PLX)

    NASA Astrophysics Data System (ADS)

    Hsu, S. C.; Awe, T. J.; Hanna, D. S.; Davis, J. S.; Witherspoon, F. D.; Cassibry, J. T.; Gilmore, M. A.; Hwang, D. Q.

    2010-11-01

    The Plasma Liner Experiment (PLX) is a multi-institutional collaboration that is exploring and demonstrating the feasibility of forming imploding spherical plasma liners to reach peak pressures ˜0.1 Mbar upon stagnation. The liners will be formed via merging of 30--60 dense high Mach number plasma jets (n˜10^17 cm-3, M˜10--35, v˜50--70 km/s, rjet˜5 cm) in spherically convergent geometry. We are aiming for two potential follow-on applications if this work is successful: (1) assembling repetitive, macroscopic (cm and μs scale) plasmas suitable for fundamental HEDLP scientific studies and (2) a standoff driver solution for magneto-inertial fusion. This is a staged project where scientific issues will be studied first at modest stored energies (˜300 kJ) before attempting to reach HED-relevant pressures (requiring ˜1.5 MJ)@. This poster provides an overview/status of the project and the research plan, which includes numerical/theoretical and experimental studies of plasma jet formation/acceleration, propagation/merging, liner convergence/stagnation, and laser driven beat waves for magnetizing the imploding liner.

  9. Gyrotron Development in the EU for Present Fusion Experiments and for ITER

    SciTech Connect

    Thumm, M.; Alberti, S.; Hogge, J.-P.; Tran, M. Q.; Yovchev, I.; Arnold, A.; Bariou, D.; Giguet, E.; Lievin, C.; Dammertz, G.; Illy, S.; Jin, J.; Piosczyk, B.; Prinz, O.; Rzesnicki, T.; Yang, X.; Darbos, C.; Magne, R.; Gantenbein, G.

    2006-01-03

    The long term strategy of the EU in the field of gyrotrons in fusion plasma applications is based on two approaches: R and D in laboratories to develop advanced concepts and industrial development of state-of-the-art tubes for use in present experiments like TCV, Tore Supra (118 GHz, 0.5 MW, CW) and W7-X (140 GHz, 1 MW, CW). The results from these two approaches are then applied to the development of a coaxial cavity gyrotron operating at 170 GHz and delivering 2 MW-CW for the electron cyclotron wave system of ITER. This paper will recall the main achievements of this program and will outline the present status of the 170 GHz coaxial cavity gyrotron development.

  10. Experiences with Two Reliability Data Collection Efforts (Presentation)

    SciTech Connect

    Sheng, S.; Lantz, E.

    2013-08-01

    This presentation, given by NREL at the Wind Reliability Experts Meeting in Albuquerque, New Mexico, outlines the causes of wind plant operational expenditures and gearbox failures and describes NREL's efforts to create a gearbox failure database.

  11. Overview on collision processes of highly charged ions with atoms present status and problems

    SciTech Connect

    Janev, R.K.

    1983-05-01

    This paper provides a brief discussion on the present status of the collision physics of highly charged ions with atoms. The emphasis is on the main achievements in understanding and describing the most important collision processes, and as charge transfer, ionization and Auger-type processes, and even more on those open problems which, due either to their scientific or practical importance, represent challenges to current research in this field. The paper concentrates on general ideas and problems whose development and solutions have advanced or will advance our basic understanding of the collision dynamics of multiply charged ions with atoms.

  12. Present status of the geochronology of the early Precambrian of South India

    NASA Technical Reports Server (NTRS)

    Gopalan, K.; Srinivasan, R.

    1988-01-01

    The present status of Precambrian geochronology of South India was summarized. Support was offered for Raith's conclusion of an extensive 3.3 to 3.4-Ga tonalite-forming event. Evidence that the Sargur supracrustal sequence predates this event, however, remains equivocal. The only reliably dated supracrustal rocks are the similar to 3.0-Ga Chitradurga acid volcanics, and these are separated from the older Bababudan supracrustals by a major gneiss-forming event. A major unsolved problem relates to the timing of the Sargur supracrustals in relation to the basal units of the Dharwar succession. An appeal was made for more geochronological work on South Indian samples.

  13. Hydrocarbon solubility and its migration processes: a look at the present status

    SciTech Connect

    Mamun, C.K.; Ohkuma, H.; Sepehrnoori, K.

    1985-12-01

    In this study we review the present status of knowledge of solubility of hydrocarbons and its implications on primary migration processes. The intent is to examine the solubility and the transportation mechanisms relevant to geopressured-geothermal reservoirs, although the discussion included here accommodates a wide range of related aspects. Influences of parameters associated with hydrocarbon (especially methane) solubility have been studied. We have sought to evaluate several primary hydrocarbon migration processes and to point out their attractive features as well as their limitations. A brief discussion of hydrocarbon generation processes is also included.

  14. Vacuum magnetic linear birefringence using pulsed fields: status of the BMV experiment

    NASA Astrophysics Data System (ADS)

    Cadène, Agathe; Berceau, Paul; Fouché, Mathilde; Battesti, Rémy; Rizzo, Carlo

    2014-01-01

    We present the current status of the BMV experiment. Our apparatus is based on an up-to-date resonant optical cavity coupled to a transverse magnetic field. We detail our data acquisition and analysis procedure which takes into account the symmetry properties of the raw data with respect to the orientation of the magnetic field and the sign of the cavity birefringence. The measurement result of the vacuum magnetic linear birefringence k CM presented in this paper was obtained with about 200 magnetic pulses and a maximum field of 6.5 T, giving a noise floor of about 8 × 10-21 T-2 at 3 σ confidence level.

  15. Testing General Relativity in the Solar System: Present Status and Possible Future Developments

    SciTech Connect

    Turyshev, Slava G.

    2010-07-12

    Series of recent experiments have successfully tested Einstein's general theory of relativity to a remarkable precision. Various experimental techniques were used to test relativistic gravity in the solar system namely spacecraft Doppler tracking, planetary ranging, lunar laser ranging, dedicated gravity experiments in space and many ground-based efforts. Here we review the foundations of general relativity, present recent progress in the tests of relativistic gravity, and discuss the advances in our understanding of fundamental physics that are anticipated in the near future.

  16. [Two cases of schizophrenia presenting with 'solar experience': the 'polysolar experience' and its progression].

    PubMed

    Harashima, Kanoko; Kobayashi, Toshiyuki; Kikuchi, Senichiro; Okajima, Yoshiro; Kato, Satoshi

    2010-01-01

    The 'solar experience' as an abnormal experience of schizophrenia in which patients directly experience the sun itself was first described by Miyamoto in 1974. Patients have delusions of the sun dying, hallucinations of the sun, and even believe that they become the sun. The patient may draw pictures of the sun similar to Edvard Munch's famous painting "The Sun". Miyamoto explained the progression of the solar experience as follows: (1) in the early stage of schizophrenia, patients believe that the sun falls or dies; (2) in the midst of the illness, they occupy the position of the sun in their delusions; and (3) in the recovery stage, they see or draw the sun against a scenic background, indicating that they no longer perceive themselves to be at the center of the world. Because of the absolute centrality of the sun, Miyamoto noted that the patient never experiences multiple suns (a 'polysolar experience'). However, in his book Memoirs of My Nervous Illness (original German title: Denkwürdigkeiten eines Nervenkranken), Daniel Paul Schreber described that he saw two suns. In this paper, the authors report two patients with schizophrenia who presented with a solar experience. Patient 1 was a man in his early forties. Fourteen years before his 'polysolar experience', he had attempted suicide, developed stupor, and was diagnosed with depression. However, he sometimes exhibited cenestopathy. Three years before the experience, he developed catatonic stupor and auditory hallucinations, and his diagnosis was changed to schizophrenia. After two months of hospitalization, the patient, in partial remission, was discharged. Ten months later, he saw two fragments tumble down from the sun, which he described as sons of the sun. Thereafter, his behavior became erratic, which led to a third hospitalization. In the recovery phase, the patient drew a picture of a large sun covering the entire piece of drawing paper and another of the sun set in scenery. Patient 2 was a married

  17. Congenital duodenal obstruction with delayed presentation: seven years of experience

    PubMed Central

    Karami, Hasan; Saneian, Hossein

    2016-01-01

    Introduction The duodenum is the most common site for congenital intestinal obstruction. The duodenal web with a central hole can present without any overt signs of obstruction at a later age. Material and methods Over a 7-year period, children with congenital intestinal obstruction were identified in this study. The complications and operative findings of patients with duodenal web with conditions such as wind sock deformity and delayed diagnosis were evaluated in this study. Results This study included 81 infants with congenital intestinal obstruction. At operation, 48 patients demonstrated duodenal obstruction with atresia in 27, annular pancreas in 15 and malrotation in 6. Also, we observed incomplete obstruction of the duodenum due to a fenestrated web in 8 patients. The age of these patients at operation time ranged from 5 days to 72 months. Fifty percent of affected patients were associated with trisomy 21, all of whom exhibited failure to thrive due to food intolerance. The patients older than 2 years presented with major complications of gastroesophageal reflux such as esophageal ulcer, stricture and dysphagia. Additionally we had a unique case of a patient who had been referred with an epigastric mass. During the operation, we found 440 seeds of various fruits in the stomach and the first portion of the duodenum. Conclusions Our study emphasizes that duodenal web with a central hole can present without signs of obstruction at a later age with only failure to thrive and food intolerance. Therefore a high index of suspicion is necessary for diagnosis when it presents beyond the usual age. PMID:27695493

  18. Solar cell experiments for space: past, present and future

    NASA Astrophysics Data System (ADS)

    Hoheisel, R.; Messenger, S. R.; Lumb, M. P.; Gonzalez, M.; Bailey, C. G.; Scheiman, D. A.; Maximenko, S.; Jenkins, P. P.; Walters, R. J.

    2013-03-01

    Since the early beginnings of the space age in the 1950s, solar cells have been considered as the primary choice for long term electrical power generation of satellites and space systems. This is mainly due to their high power/mass ratio and the good scalability of solar modules according to the power requirements of a space mission. During the last decades, detailed solar cell material studies including the non-trivial interaction with high-energy space particles have led to continuous and significant improvements in device efficiency. This allowed the powering of advanced space systems like the International Space Station, rovers on the Martian surface as well as satellites which have helped to understand the universe and our planet. It is noteworthy that in addition to their success in space, these photovoltaic technologies have also broken ground for the application of photovoltaic systems in terrestrial systems. This paper discusses the development of space solar cells, gives insight into related experiments like the analysis of the interaction with space particles and provides an overview on challenges and requirements for future space missions.

  19. Experience with CPV Module Failures at NREL (Presentation)

    SciTech Connect

    Muller, M.

    2012-03-01

    The failures and performance issues associated with three years of on-sun testing of CPV modules are discussed. Pictures of various failure mechanisms and performance issues are presented. A wide array of CPV module failures and performance issues have been experienced at NREL. Many of the modules are prototypes and have not been through qualification testing. It is assumed that the qualification test would have captured many of the problems. Internal lens soiling due to condensation is not currently captured by the qualification test. Lens temperature dependence can be built into modeling if CPV is to operate in cold locations.

  20. Wearable system-on-a-chip UWB radar for contact-less cardiopulmonary monitoring: present status.

    PubMed

    Zito, D; Pepe, D; Mincica, M; Zito, F; De Rossi, D; Lanata, A; Scilingo, E P; Tognetti, A

    2008-01-01

    The present status of the project aimed at the realization of an innovative wearable system-on-chip UWB radar for the cardiopulmonary monitoring is presented. The overall system consists of a wearable wireless interface including a fully integrated UWB radar for the detection of the heart beat and breath rates, and a IEEE 802.15.4 ZigBee low-power radio interface. The principle of operation of the UWB radar for the monitoring of the heart wall is summarized. With respect to the prior art, this paper reports the results of the experimental characterization of the intra-body channel loss, which has been carried out successfully in order to validate the theoretical model employed for the radar system analysis. Moreover, the main building blocks of the radar have been manufactured in 90 nm CMOS technology by ST-Microelectronics and the relevant performance are resulted in excellent agreement with those expected by post-layout simulations. PMID:19163907

  1. Present status of GaAs. [including space processing and solid state applications

    NASA Technical Reports Server (NTRS)

    Gatos, H. C.; Lagowski, J.; Jastrzebski, L.

    1979-01-01

    An extensive literature survey on GaAs was carried out for the period December 31, 1970, to December 31, 1977. The increasing interest in GaAs device structures increased steadily during that period. The leading research and development centers and the specific areas of interest were identified. A workshop on GaAs was held in November 1977 to assess the present status of melt-grown GaAs and the existing needs for reliable chemical, structural, and electronic characterization methods. It was concluded that the present available bulk GaAs crystals are of poor quality and that GaAs technology is lagging demonstrated or potentially feasible GaAs devices and systems.

  2. Thermal hydraulic codes for LWR safety analysis - present status and future perspective

    SciTech Connect

    Staedtke, H.

    1997-07-01

    The aim of the present paper is to give a review on the current status and future perspective of present best-estimate Thermal Hydraulic codes. Reference is made to internationally well-established codes which have reached a certain state of maturity. The first part of the paper deals with the common basic code features with respect to the physical modelling and their numerical methods used to describe complex two-phase flow and heat transfer processes. The general predictive capabilities are summarized identifying some remaining code deficiencies and their underlying limitations. The second part discusses various areas including physical modelling, numerical techniques and informatic structure where the codes could be substantially improved.

  3. The NUSTAR program at FAIR. Overview and present status of the project

    NASA Astrophysics Data System (ADS)

    Herlert, Alexander

    2014-04-01

    The NUSTAR Collaboration brings together several hundred scientists to form one of the four scientific pillars of the future FAIR facility. NUSTAR aims at the exploitation of intense radioactive beams with energies up to 1.5 GeV/u in order to explore nuclei with large neutron or proton excess. The project has evolved over the last years and now reached a state where a large fraction of the core program is financed, partly built, and even ready for operation. With the signing of the FAIR convention in 2010 and the start of construction, the sub-projects in NUSTAR gain momentum and look forward to commissioning and first beams in this decade. The present status of the project will be presented, focusing on the instrumentation to be applied in the various experimental areas behind the Super-FRS fragment separator, which is the central instrument of NUSTAR.

  4. Fens and floodplains of the temperate zone: Present status, threats, conservation and restoration

    USGS Publications Warehouse

    Van Diggelen, R.; Middleton, B.; Bakker, J.; Grootjans, A.; Wassen, M.

    2006-01-01

    This Special Feature focuses on lowland fens and flood plains. In this introduction we discuss the most important mire-related terms, present status, threats and conservation and restoration attempts. Floodplains and especially lowland fens are rare and vulnerable ecosystems. They are highly threatened all over the world because of direct conversion to agricultural land and especially the lack of appropriate management and altered catchment hydrology. Finally we present a framework for the conservation and restoration of these ecosystems. This consists of (1) optimising abiotic conditions; (2) safeguarding propagule availability of the target species; (3) creating and maintaining conditions for (re)establishment of these species, and (4) appropriate management to keep the conditions suitable. ?? IAVS; Opulus Press.

  5. Wearable system-on-a-chip UWB radar for contact-less cardiopulmonary monitoring: present status.

    PubMed

    Zito, D; Pepe, D; Mincica, M; Zito, F; De Rossi, D; Lanata, A; Scilingo, E P; Tognetti, A

    2008-01-01

    The present status of the project aimed at the realization of an innovative wearable system-on-chip UWB radar for the cardiopulmonary monitoring is presented. The overall system consists of a wearable wireless interface including a fully integrated UWB radar for the detection of the heart beat and breath rates, and a IEEE 802.15.4 ZigBee low-power radio interface. The principle of operation of the UWB radar for the monitoring of the heart wall is summarized. With respect to the prior art, this paper reports the results of the experimental characterization of the intra-body channel loss, which has been carried out successfully in order to validate the theoretical model employed for the radar system analysis. Moreover, the main building blocks of the radar have been manufactured in 90 nm CMOS technology by ST-Microelectronics and the relevant performance are resulted in excellent agreement with those expected by post-layout simulations.

  6. [The influence of exercise therapy on the psychological status of women presenting with osteoporosis].

    PubMed

    Menduksheva, Iu E; Kirpikova, M N; Shutemova, E A

    2010-01-01

    The objective of the present study was to evaluate effectiveness of correction of the psychological status of postmenopausal women suffering primary osteoporosis (OP) by means of exercise therapy. Diagnosis of OP was verified by dual energy X-ray absorptiometry. The degree of depression was assessed using the CES-D questionnaire and that of reactive anxiety by the C.D. Spielberger and Yu.L. Khanin method. A visual-analogue scale was used to obtain self-assessment of the patients' health and pain intensity. Physical rehabilitation was shown to cause reduction of reactive anxiety and alleviate pain syndrome. As a result, the quality of the patients' life improved regardless of OP severity. However, beneficial effect of exercise therapy was apparent only in patients presenting with mild and moderately severe anxiety/depressive disorders but was lacking in more serious cases.

  7. HHV-6 encephalitis presenting as status epilepticus in an immunocompetent patient

    PubMed Central

    Shahani, Lokesh

    2014-01-01

    Human herpes virus 6 (HHV-6) infections are frequently detected in patients with immunosuppressed transplant; however, reactivation in an immunocompetent patient is rarely reported. The author reports the case of a 65-year-old woman presenting with status epilepticus with foci in the temporal and occipital lobe and MRI suggestive of encephalitis in the parietal, occipital and temporal regions. The cerebrospinal fluid (CSF) analysis showed normal cell counts, protein and glucose levels and hence viral aetiologies were considered. The patient's workup returned positive for HHV-6 in serum as well as CSF. The patient responded well to a 21-day course of antivirals with complete resolution of her symptoms. This case highlights the importance of considering HHV-6 encephalitis even among immunocompetent patients presenting with encephalitis and having signs of temporal lobe involvement. PMID:25239996

  8. Social status and shaming experiences related to adolescent overt aggression at school.

    PubMed

    Aslund, Cecilia; Starrin, Bengt; Leppert, Jerzy; Nilsson, Kent W

    2009-01-01

    Feelings of rejection and humiliation in interpersonal interaction are strongly related to aggressive behavior. The aim of this study was to investigate the association between social status, shaming experiences, gender and adolescent aggressive behavior by using a status-shaming model. A population-based sample of 5,396 adolescents aged from 15 to 18 completed a questionnaire that asked questions regarding psychosocial background, shaming experiences, social status of family, peer group and school and involvement in physical or verbal aggression at school. Shaming experiences, i.e. being ridiculed or humiliated by others, were strongly related to aggressive behavior. Social status and shaming were related in the prediction of aggressive behavior, suggesting that a person's social status may influence the risk for taking aggressive action when subjected to shaming experiences. Medium social status seemed to have a protective function in the association between shaming experiences and aggression. This study confirms the importance of further evaluation of the role of perceived social status and shaming experiences in the understanding of aggressive behavior. Moreover, the results indicate the need for different kinds of status measures when investigating the associations between status and behavior in adolescent populations. The results may have important implications for the prevention of bullying at school as well as other deviant aggressive behavior among adolescents. PMID:18925634

  9. The meaning of DNR status: oncology nurses' experiences with patients and families.

    PubMed

    Jezewski, M A; Finnell, D S

    1998-06-01

    Patients, providers, and families are increasingly involved in end-of-life decisions (advance directives, health care proxy, do-not-resuscitate [DNR] status consents). These decisions can be complex processes whereby the participants in the process must come to terms with often painful and difficult decisions. The role perception of the nurse in end-of-life decision making is not well delineated. This chapter explores the results of a study that addresses the question, "What are the experiences of oncology nurses as they interact with patients and/or family members during the process of patients/families signing DNR consents. The grounded theory method of data collection and analysis was used to explore this question. The results of the study indicate that central to the process of consenting to DNR status is the degree of shared understanding about the meaning of DNR status among participants and the conflict that can occur when meanings are not shared. A model is presented that illustrates the connections between the meanings of DNR (patient, family, and provider) and congruence and conflict in the DNR consent process. Strategies are discussed that facilitate prevention or resolution of conflict in the DNR status decision-making process. Strategies used by the nurse to facilitate decision making by patient and families include communicating with, caring for, educating, advocating for, and collaborating with patients, families, and other providers. PMID:9615512

  10. From laboratory to industry Phasics experience (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wattellier, Benoit F.; Lebrun, Marie-Begoña.

    2016-03-01

    We describe several examples of technology transfer from academic laboratories to PHASICS. PHASICS was created in 2003 as a spin-off of LULI an academic laboratory working on plasma physics and developing high power lasers to create such objects which temperature and pressure conditions are close to those at the center of stars. In order to optimize the intensity at laser focus, several thesis treated the subject of adaptive optics for lasers. LULI decided to collaborate with ONERA who just invented a technique for wave front sensing called multiwave lateral shearing interferometry. Though developed at first for infrared metrology applications, this technique proved to be very efficient with lasers because it was able to analyze wave front of modulated beams with sharp edges. Before being industrialized the technique was further improved to a compact version called quadriwave lateral shearing interferometry. As soon as PHASICS was created, we felt the potential of making wave front images from transparent objects because of QWLSI high spatial resolution. PHASICS and Institut Fresnel started a collaboration to study applications in microscopy imaging. Research subjects include biological imaging, CARS microscopy, anisotropy imaging, or laser damage testing. The results of research were then included in PHASICS products but sometimes only a tool developed during the project became a product. We will present research works that led to transfers as well as the method we used to ensure fruitful collaboration and transfer.

  11. Health and environmental impact of mercury: Past and present experience

    NASA Astrophysics Data System (ADS)

    Rivera, A. T. F.; Cortes-Maramba, N. P.; Akagi, H.

    2003-05-01

    Mercury exists in various forms including metallic mercury, inorganie and organic mercury compounds. Research studies show that contamination brought about by natural and man-made activities is clearly a growing problem today. In 1956, the first recognized poisoning outbreaks occurred. Minamata Disease is a disorder of the central nervous system caused by the consumption of fish and shellfish contaminated with methylmercury. Clinical manifestation differs from inorganic mercury poisoning in which the kidneys and the renal system are damaged. The toxidrome consists of sensory disorders in the distal portion of the four extremities, cerebral ataxia, bilateral concentric constriction of the visual field. central disorder of ocular movement, central hearing impairment and disequilibrium. Fetal type Minamata Disease bom of mothers being exposed to methylmercury during pregnancy resulted in conditions similar to those associated with “infantile cerebral palsy" were also documented. Measures to control environmental pollution were implemented such as the environmental restoration project, compensation and relief of victims as part of the health and environmental management undertaken by the government. At present, global research studies are focusing on long-term and low-dose inorganic and methyl mercury exposure; and developmental neurobehavioral toxicity including relevant environmental factors influencing mercury transformations, mass balances and partitioning in ecosystems.

  12. High-energy synchrotron radiation x-ray microscopy: Present status and future prospects

    SciTech Connect

    Jones, K.W.; Gordon, B.M.; Spanne, P. ); Rivers, M.L.; Sutton, S.R. )

    1991-01-01

    High-energy radiation synchrotron x-ray microscopy is used to characterize materials of importance to the chemical and materials sciences and chemical engineering. The x-ray microscope (XRM) forms images of elemental distributions fluorescent x rays or images of mass distributions by measurement of the linear attenuation coefficient of the material. Distributions of sections through materials are obtained non-destructively using the technique of computed microtomography. The energy range of the x rays used for the XRM ranges from a few keV at the minimum value to more than 100 keV, which is sufficient to excite the K-edge of all naturally occurring elements. The work in progress at the Brookhaven NSLS X26 and X17 XRM is described in order to show the current status of the XRM. While there are many possible approaches to the XRM instrumentation, this instrument gives state-of-the-art performance in most respects and serves as a reasonable example of the present status of the instrumentation in terms of the spatial resolution and minimum detection limits obtainable. The examples of applications cited give an idea of the types of research fields that are currently under investigation. They can be used to illustrate how the field of x-ray microscopy will benefit from the use of bending magnets and insertion devices at the Advanced Photon Source. 8 refs., 5 figs.

  13. Free-ocean CO2 enrichment (FOCE) systems: present status and future developments

    NASA Astrophysics Data System (ADS)

    Gattuso, J.-P.; Kirkwood, W.; Barry, J. P.; Cox, E.; Gazeau, F.; Hansson, L.; Hendriks, I.; Kline, D. I.; Mahacek, P.; Martin, S.; McElhany, P.; Peltzer, E. T.; Reeve, J.; Roberts, D.; Saderne, V.; Tait, K.; Widdicombe, S.; Brewer, P. G.

    2014-08-01

    Free-ocean CO2 enrichment (FOCE) systems are designed to assess the impact of ocean acidification on biological communities in situ for extended periods of time (weeks to months). They overcome some of the drawbacks of laboratory experiments and field observations by enabling (1) precise control of CO2 enrichment by monitoring pH as an offset of ambient pH, (2) consideration of indirect effects such as those mediated through interspecific relationships and food webs, and (3) relatively long experiments with intact communities. Bringing perturbation experiments from the laboratory to the field is, however, extremely challenging. The main goal of this paper is to provide guidelines on the general design, engineering, and sensor options required to conduct FOCE experiments. Another goal is to introduce xFOCE, a community-led initiative to promote awareness, provide resources for in situ perturbation experiments, and build a user community. Present and existing FOCE systems are briefly described and examples of data collected presented. Future developments are also addressed as it is anticipated that the next generation of FOCE systems will include, in addition to pH, options for oxygen and/or temperature control. FOCE systems should become an important experimental approach for projecting the future response of marine ecosystems to environmental change.

  14. (237)Np(n,f) Cross Section: New Data and Present Status

    SciTech Connect

    Paradela, C.; Koehler, Paul Edward; N_TOF collaboration,

    2011-01-01

    In this document, we present the final result obtained at the n-TOF experiment for the neutron-induced fission cross section of the {sup 237}Np, from the fission threshold up to 1 GeV. The method applied to get this result is briefly discussed. n-TOF data are compared to the last experimental measurements using other TOF facilities or the surrogate method, reported experiments performed with monoenergetic sources and the FISCAL systematic, including a discussion about the existing discrepancies.

  15. Status of the T2L2/Jason2 Experiment

    NASA Astrophysics Data System (ADS)

    Exertier, Pierre; Samain, Etienne; Bonnefond, Pascal; Guillemot, Philippe

    2010-12-01

    The T2L2 (Time Transfer by Laser Link) project, developed by CNES and OCA will permit the synchronization of remote ultra stable clocks and the determination of their performances over intercontinental distances. The principle of the experiment derives from Satellite Laser Ranging (SLR) technology with dedicated space equipment. T2L2 was accepted in 2005 to be on board the Jason2 altimetry satellite. The payload consists of both event timer and photo detection modules. The system uses the ultra-stable quartz oscillator of DORIS as on-board reference clock on one hand, and the Laser Reflector Array, making T2L2 a real two-way time transfer system on the other hand. The expected time stability of the T2L2 instrument (detection and timing), referenced by the DORIS oscillator and including all internal error sources should be at the level of 10-12 ps at 1 s and <1 ps at 1000 s. The metrological specifications of T2L2 should permit to maintain a precision of 1 to a few ps when measuring the phase of a clock during around 1000 seconds. First analysis of T2L2 data permitted to validate some important characteristics of the experiment such as the sensitivity of the instrument to laser pulse amplitude (from single to multi-photon detection mode), data noises (of different sources, SLR and T2L2), and first error budget and time stability of ground to space time transfers. The paper describes the space experiment and highlights the different steps of the data processing after a first year of operations (between July 2008 and June 2009). We show the time stability which can be reached when a laser station is equipped with an Hydrogen Maser or a Cesium clock as a time reference; thus, the first estimations give 7 ps over 30 s. We conclude by presenting the campaigns of ground to ground time transfers already planned between the Paris Observatory and different places in Europe.

  16. Linkage disequilibrium and association studies in higher plants: present status and future prospects.

    PubMed

    Gupta, Pushpendra K; Rustgi, Sachin; Kulwal, Pawan L

    2005-03-01

    During the last two decades, DNA-based molecular markers have been extensively utilized for a variety of studies in both plant and animal systems. One of the major uses of these markers is the construction of genome-wide molecular maps and the genetic analysis of simple and complex traits. However, these studies are generally based on linkage analysis in mapping populations, thus placing serious limitations in using molecular markers for genetic analysis in a variety of plant systems. Therefore, alternative approaches have been suggested, and one of these approaches makes use of linkage disequilibrium (LD)-based association analysis. Although this approach of association analysis has already been used for studies on genetics of complex traits (including different diseases) in humans, its use in plants has just started. In the present review, we first define and distinguish between LD and association mapping, and then briefly describe various measures of LD and the two methods of its depiction. We then give a list of different factors that affect LD without discussing them, and also discuss the current issues of LD research in plants. Later, we also describe the various uses of LD in plant genomics research and summarize the present status of LD research in different plant genomes. In the end, we discuss briefly the future prospects of LD research in plants, and give a list of softwares that are useful in LD research, which is available as electronic supplementary material (ESM).

  17. Intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: present status and practical therapeutic guidelines.

    PubMed

    Dalakas, M C

    1999-11-01

    This review summarizes the current status of intravenous immunoglobulin (IVIg) in the treatment of autoimmune neuromuscular disorders and the possible mechanisms of action of the drug based on work in vivo, in vitro, and in animal models. Supply of idiotypic antibodies, suppression of antibody production, or acceleration of catabolism of immunoglobulin G (IgG) are relevant in explaining the efficacy of IVIg in myasthenia gravis (MG), Lambert-Eaton myasthenic syndrome (LEMS), and antibody-mediated neuropathies. Suppression of pathogenic cytokines has putative relevance in inflammatory myopathies and demyelinating neuropathies. Inhibition of complement binding and prevention of membranolytic attack complex (MAC) formation are relevant in dermatomyositis (DM), Guillain-Barré syndrome (GBS), and MG. Modulation of Fc receptors or T-cell function is relevant in chronic inflammatory demyelinating polyneuropathy (CIDP), GBS, and inflammatory myopathies. The clinical efficacy of IVIg, based on controlled clinical trials conducted in patients with GBS, CIDP, multifocal motor neuropathy (MMN), DM, MG, LEMS, paraproteinemic IgM anti-myelin-associated glycoprotein (anti-MAG) demyelinating polyneuropathies, and inclusion body myositis is summarized and practical issues related to each disorder are addressed. The present role of IVIg therapy in other disorders based on small controlled or uncontrolled trials is also summarized. Finally, safety issues, risk factors, adverse reactions, spurious results or serological tests, and practical guidelines associated with the administration of IVIg in the treatment of neuromuscular disorders are presented.

  18. Status of the RBCC Direct-Connect Mixer Combustor Experiment

    NASA Technical Reports Server (NTRS)

    Walker, James F.; Kamhawi, Hani; Krivanek, Thomas M.; Thomas, Scott R.; Smith, Timothy D.

    2002-01-01

    The NASA Glenn Research Center is developing hydrogen based combined cycle propulsion technology for a single-stage-to-orbit launch vehicle application under a project called GTX. Rocket Based Combined Cycle (RBCC) propulsion systems incorporate one or more rocket engines into an airbreathing flow path to increase specific impulse as compared to an all rocket-powered vehicle. In support of this effort, an RBCC direct-connect test capability was established at the Engine Components Research Laboratory to investigate low speed, ejector ramjet, and initial ramjet operations and performance. The facility and test article enables the evaluation of two candidate low speed operating schemes; the simultaneous mixing and combustion (SMC) and independent ramjet stream (IRS). The SMC operating scheme is based on the fuel rich operations of the rocket where performance depends upon mixing between the rocket plume and airstream. In contrast, the IRS scheme fuels the airstream separately and uses the rocket plume to ignite the fuel-air mixture. This paper describes the test hardware and facility upgrades installed to support the RBCC tests. It also defines and discusses low speed technical challenges being addressed by the experiments. Finally, preliminary test results, including rocket risk mitigating tests, unfueled airflow tests, and the integrated system hot fire test will be presented.

  19. Status report of the Thomson spectrometer for LILIA experiment

    NASA Astrophysics Data System (ADS)

    Maggiore, M.; Cirrone, G. A. P.; Romano, F.; Caruso, A.; Caruso, G.; Longhitano, A.; Messina, G.; Passarello, S.; Rizzo, D.; Salomone, S.; Zappalà, E.

    2013-06-01

    LILIA is an experiment of light ions acceleration trough laser interaction with thin metal targets to be done at the FLAME facility, which is now running in INFN-LNF of Frascati (Rome). In the framework of LILIA, the LNS is involved in the design and construction of a spectrometer based on the Thomson's configuration in order to diagnostic the ion ejection from the laser-generated plasma. The main goal is to realize a compact system which is both very practical and optimized with regard to the mass and energy resolution of particles obtained by laser-plasma interactions. The preliminary design has to be able to analyze and resolve beams of protons and ions up the total energy of 10 MeV. However, the technical choices adopted in this prototype have to be applied for the final device concerning a challenging spectrograph able to analyze beams of 150 MeVof total energy. The magnetic and the electric part have been built and these have been assembled. The vacuum and the high voltage test have been accomplished out and also the magnetic measurements. The results will be presented and discussed.

  20. Status of the Fermilab Muon (g-2) Experiment

    SciTech Connect

    Roberts, B.Lee

    2010-01-01

    The New Muon (g-2) Collaboration at Fermilab has proposed to measure the anomalous magnetic moment of the muon, a{sub {mu}}, a factor of four better than was done in E821 at the Brookhaven AGS, which obtained a{sub {mu}} = [116592089(63)] x 10{sup -11} {+-} 0.54 ppm. The last digit of a{sub {mu}} is changed from the published value owing to a new value of the ratio of the muon-to-proton magnetic moment that has become available. At present there appears to be a difference between the Standard-Model value and the measured value, at the {approx}= 3 standard deviation level when electron-positron annihilation data are used to determine the lowest-order hadronic piece of the Standard Model contribution. The improved experiment, along with further advances in the determination of the hadronic contribution, should clarify this difference. Because of its ability to constrain the interpretation of discoveries made at the LHC, the improved measurement will be of significant value, whatever discoveries may come from the LHC.

  1. Status of CFD validation on the vortex flow experiment

    NASA Astrophysics Data System (ADS)

    Wagner, B.; Hitzel, S. M.; Schmatz, M. A.; Schwarz, W.; Hilgenstock, A.; Scherr, S.

    1988-12-01

    The vortex flow phenomena developing at highly swept wings by leading edge separation are of great interest for fighter and missile aerodynamics. While panel methods are already known for more than a decade to satisfactorily model the roll-up of the corresponding vortex sheets at subsonic speed, Euler methods became available in the early 80's for predicting these effects also in the transonic and supersonic speed ranges. Subsequent trials to validate such transonic vortex flow computations revealed the experimental data basis to be very poor for high speeds and, in consequence, the International Vortex Flow Experiment on Euler Code Validation was set up. More recently, also three dimensional Navier-Stokes codes could be applied in order to clarify the role of viscous effects and to investigate in detail the neglect of those in the Euler solutions. A survey is presented on the Euler code validation based on the Symposium on the IVFE in 1986 and additional insight is given into some related Euler and Navier-Stokes work done in West Germany more recently.

  2. Two-photon exchange in elastic ep scattering and the status of the OLYMPUS experiment

    NASA Astrophysics Data System (ADS)

    Hasell, Douglas; Olympus Collaboration

    2014-09-01

    Two-photon exchange in elastic ep scattering is believed to explain the observed discrepancy in the proton electric to magnetic form factor ratio, μpGEp /GMp , measured by Rosenbluth separation and by polarization transfer methods. To quantitatively determine the contribution of two-photon exchange to elastic scattering the OLYMPUS experiment was proposed and operated at the DESY laboratory in Hamburg, Germany to measure the ratio in the elastic scattering cross sections, σe+ p /σe- p . The OLYMPUS experiment used the positron and electron beams of the DORIS storage ring at a beam energy of 2.01 GeV incident on a windowless, internal, hydrogen gas target. A left/right symmetric detector measured the rates for elastic scattering over a broad kinematic range together with a redundant set of luminosity monitors. Approximately 4.45 fb-1 of integrated luminosity was collected. The current status of the OLYMPUS analysis will be presented.

  3. Radiotherapy infrastructure and human resources in Europe - present status and its implications for 2020.

    PubMed

    Datta, Niloy Ranjan; Samiei, Massoud; Bodis, Stephan

    2014-10-01

    Radiotherapy (RT) is required for nearly half of the newly diagnosed cancer patients. To optimise the quality and availability of RT, guidelines have been proposed by European Society for Radiotherapy and Oncology-QUAntification of Radiation Therapy Infrastructure And Staffing Needs (ESTRO-QUARTS) and the International Atomic Energy Agency (IAEA). This study evaluates the present status of RT capacity in Europe and the projected needs by 2020 as per these recommendations. Thirty-nine of the 53 countries, listed in Europe by the UN Statistical Division, whose cancer incidences, teletherapy and human resources were available in the Global Cancer Incidence, Mortality and Prevalence (GLOBOCAN), International Agency for Research on Cancer (IARC) and DIrectory of RAdiotherapy Centres (DIRAC) (IAEA) databases were evaluated. A total of 3550 teletherapy units (TRT), 7017 radiation oncologists (RO), 3685 medical physicists (MP) and 12,788 radiotherapy technologists (RTT) are presently available for the 3.44 million new cancer cases reported annually in these countries. The present infrastructure and human resources in RT are estimated to provide RT access to 74.3% of the patients requiring RT. The current capacity in TRT, RO, MP and RTT when compared with recommended guidelines has a deficit of 25.6%, 18.3%, 22.7% and 10.6%, respectively. Thus, to respond to requirements by 2020, the existing capacity needs to be augmented by an additional 1698 TRTs, 2429 ROs, 1563 MPs and 2956 RTTs. With an imminent rise in cancer incidence, multifaceted strategic planning at national and international levels within a coordinated comprehensive cancer control programme is highly desirable to give adequate access to all patients who require radiotherapy across Europe. Specific steps to address this issue at national and continental levels involving all major stakeholders are proposed.

  4. The present status of xeroderma pigmentosum in Japan and a tentative severity classification scale.

    PubMed

    Nakano, Eiji; Masaki, Taro; Kanda, Fumio; Ono, Ryusuke; Takeuchi, Seiji; Moriwaki, Shinichi; Nishigori, Chikako

    2016-08-01

    Xeroderma pigmentosum (XP) is a rare autosomal recessive hereditary disease. Patients with XP have severe hypersensitivity to sunlight, resulting in skin cancers, and some patients have neurological symptoms. In Japan, XP complementation group A (XP-A) is the most common form, and it is associated with severe neurological symptoms. We performed a nationwide survey on XP to determine the present status of XP in Japan. The distribution of complementation groups in Japan was considerably different from that in other countries, but there was a higher frequency in group A and the variant type, which is similar to previous reports in Japan. Basal cell carcinoma was the most frequent skin cancer that patients with XP developed, followed by squamous cell carcinoma and malignant melanoma. The frequency of these skin cancers in patients with XP-A has decreased, and these skin cancers have been occurring in much older people than those previously observed. Diagnosing XP in patients at younger ages seems to encourage patients and their parents to use sun protection, which helps prevent skin cancer. We also created a tentative scale for classifying the severity of XP, and we evaluated the neurological symptoms of XP-A using this severity scale. Our classification correlated well with patients' age, suggesting that it may be useful and feasible in clinical practice to assess the progression of symptoms of each patient with XP and evaluate the effects of treatment in the future. PMID:27539899

  5. Present Status of Venus Climate Orbiter (Planet-C) development in Japan

    NASA Astrophysics Data System (ADS)

    Nakamura, Masato

    Venus Climate Orbiter (VCO) is the first Japanese Venus orbiter to be launched in 2010. It aims at studying the atmospheric dynamics of Venus. We keep the time schedule of VCO development at ISAS/JAXA with the collaboration with university researchers and industrial engineers. In this talk we will report the present status of the VCO development in 2008. We have finished the Proto-Model integration test of major components of VCO in December 2007. Mechanical engineering model of the spacecraft has been built and its evaluation was done at Tsukuba Space Center and Sagamihara campus. The vibration levels are mostly consistent with the results from the mathematical modeling. It has been converted to the Thermal test model and is under evaluation in the thermal vacuum chamber at Sagamihara. In March 2008, we had the CDR for the phase-up (to Phase D). After the CDR, flight model of VCO has been built by NEC Corp. and ISAS/JAXA. It will be finalized by 2009 and the final integration test will be done during whole 2009.

  6. [History and present status of butterfly monitoring in Europe and related development strategies for China].

    PubMed

    Fang, Li-Jun; Xu, Hai-Gen; Guan, Jian-Ling

    2013-09-01

    Butterfly is an important bio-indicator for biodiversity monitoring and ecological environment assessment. In Europe, the species composition, population dynamics, and distribution pattern of butterfly have been monitored for decades, and many long-term monitoring schemes with international effects have been implemented. These schemes are aimed to assess the regional and national variation trends of butterfly species abundance, and to analyze the relationships of this species abundance with habitat, climate change, and other environmental factors, providing basic data for researching, protecting, and utilizing butterfly resources and predicting environmental changes, and playing important roles in the division of butterfly' s threatened level, the formulation of related protection measures, and the protection and management of ecological environment. This paper reviewed the history and present status of butterfly monitoring in Europe, with the focus on the well-known long-term monitoring programs, e. g. , the UK Butterfly Monitoring Scheme and the Germany and European Union Butterfly Monitoring Scheme. Some specific proposals for conducting butterflies monitoring in China were suggested.

  7. Status of the TREK/E36 Experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kohl, Michael; TREK Collaboration

    2014-09-01

    The TREK/E36 experiment is scheduled to run in 2015 at the J-PARC K1.1BR kaon beamline. The experiment uses a scintillating fiber target to stop a beam of up to 106 positive kaons per second. The kaon decay products are detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a photon calorimeter with large solid angle and redundant particle identification systems. With the aim to test lepton universality in the Ke 2 /Kμ 2 ratio with high precision, the experiment is highly sensitive to new physics beyond the Standard Model. A further goal of E36 is to search for light new particles with masses up to a few hundred MeV/c2 such as sterile neutrinos or U(1) bosons, which could be associated with dark matter or explain established muon-related anomalies. An overview of the planned experiment and the current project status will be presented. The TREK/E36 experiment is scheduled to run in 2015 at the J-PARC K1.1BR kaon beamline. The experiment uses a scintillating fiber target to stop a beam of up to 106 positive kaons per second. The kaon decay products are detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a photon calorimeter with large solid angle and redundant particle identification systems. With the aim to test lepton universality in the Ke 2 /Kμ 2 ratio with high precision, the experiment is highly sensitive to new physics beyond the Standard Model. A further goal of E36 is to search for light new particles with masses up to a few hundred MeV/c2 such as sterile neutrinos or U(1) bosons, which could be associated with dark matter or explain established muon-related anomalies. An overview of the planned experiment and the current project status will be presented. This project has been supported by DOE Early Career Award DE-SC0003884.

  8. Present Status of Geophysics Departments at Universities in Turkey from Perspectives of their Students

    NASA Astrophysics Data System (ADS)

    Karabulut, Savas; Baris Aygordu, Ozan; Benli, Aral

    2015-04-01

    This survey was conducted in order to make the students who are having geophysical engineering education in Turkey evaluate their departments from their own perspectives.By doing this we aimed to make a contribution to the geophysical engineering education and we tried to find out if there were any deficiencies in that matter and also the possible solutions.In this respect aproximately 500 undergraduates from 11 different state universities were asked 25 questions regarding both their socio-economic status and their ideas on their future professions.In the survey the students were asked to state their high-school graduation;whether it is an Anatolian High-school,Vocational high-school or college and if geophysical engineering education was their first choice at the university entrance exams.The students' foreign language status-if there were any- except their mother tongue were asked and also their opinions on geophysical education at their universities.Besides these the students were asked in which fields they study in their department; Seismology, Geophysics or Applied Geophysics and if they found the geophysical equipments adequate in their departments and also the programming languages-like data processing laboratories.In the survey we tried to find out if the students were encouraged to participate in the meetings and congresses in their field by their instructers and if they found the theoretical training adequate besides the practical one.Above all the students answered questions if they had any worries about future job opportunities ; what their goals were after they graduate and if they could easily get access to any kind of Turkish sources in their field and if they were reluctant to work at any jobs part-time or full-time during university.The results of the survey were presented to the Union of Turkish Engineers and Architects and also to the related heads of departments.The most striking parts of this survey were that the students were not edequate

  9. X-ray Microscopy Beamlines at SSRF--Present Status and Future Plan

    SciTech Connect

    Xu, H.; Yu, X.; Tai, R.

    2011-09-09

    The Shanghai Synchrotron Radiation Facility (SSRF) is a 3.5-GeV third-generation light source. The facility has been open for user experiments since May, 2009. This high-brightness x-ray source is an ideal platform for x-ray microscopy. Presently, SSRF has three beamlines related to x-ray microscopy or imaging, namely the soft x-ray spectromicroscopy beamline (STXM), the hard x-ray microfocusing beamline, and the x-ray imaging beamline. The construction of SSRF phase-II beamlines will be carried out during 2011-2017. Seven additional beamlines for x-ray microscopy or imaging will be built.

  10. The present status of medical physics education and training in Europe: an EFOMP survey.

    PubMed

    Eudaldo, T; Olsen, K

    2008-03-01

    The aim of this work is to present the results of an EFOMP's survey on the status of Education and Training of Medical Physics in Europe. This survey has been undertaken by EFOMP in 2005, to update the document "Policy Statement No. 1", which represents the starting point of the EFOMP recommendations on Education and Training in Medical Physics. Ultimate results have been collected at the end of 2006. To perform the survey, a questionnaire was sent to 34 National Member Organisations (NMOs) for Medical Physics, to collect information on the present state of education and training in each European country. Twenty-five countries participated in the enquiry and responded to it. The most outstanding results are as follows: In all countries, the basic requirement to enter the Medical Physics education is a university degree. The length of this university education ranges from 2 to 5 years. Concerning the Post-graduate education in Medical Physics: A nationally approved educational programme is in operation in 16 of the 25 countries. Postgraduate education takes place essentially within 3 different approaches and the total length of Medical Physics education and training ranges from 2 1/2 years to 9 years. In 14 countries, it is mandatory to hold a diploma or license to work as a Medical Physicist. It allows working in all areas of competence (the most mentioned were Radiotherapy, Nuclear Medicine, Diagnostic Radiology and Radiation Protection) in 14 countries, whereas in 4 countries it allows to work only in 1 or 2 areas. Seventeen countries have a register for Medical Physicists. A formal CPD (Continuing Professional Development) programme is in operation in 13 countries.

  11. Present status of developments in physical sorption cooling for space applications

    NASA Astrophysics Data System (ADS)

    Benthem, B.; Doornink, J.; Boom, E.; Holland, H. J.; Lerou, P. P. P. M.; Burger, J. F.; ter Brake, H. J. M.

    2014-11-01

    A sorption cooler uses the Joule-Thomson effect for cooling a gas by expanding it through a flow restriction. The flow of gas is sustained by a compressor consisting of one or more sorption cells, which cyclically adsorb and desorb gas according to the fully reversible process of physical sorption. The technology has been shown to provide active cooling in the cryogenic temperature range without exporting vibrations or electromagnetic interference. Due to full reversibility of the process and the absence of moving parts (apart from check valves, which open and close with a very low frequency), such a cooler has the potential for a very long life and high reliability. This paper starts with a recapitulation of the principles of physical sorption cooling followed by an overview of the strengths and weaknesses of the technology in relation to other space cooling technologies, such as pulse-tube cooling and Stirling cooling. Next, the present status of physical sorption cooling technology is presented based on developments previously and currently being performed by the University of Twente, Dutch Space and Kryoz Technologies. A summary will be given of the various existing demonstrator- and lab-models which have been built, along with an overview of the tests which have so far been performed. The central result of this paper is an assessment of the current Technology Readiness Level (TRL) of various sorption cooler configurations, along with their application range in terms of temperatures, heat loads and mission profile. Finally, an outline is given on the way forward currently being pursued by the developers to achieve full maturity of the technology.

  12. Gravitation theory - Empirical status from solar system experiments.

    NASA Technical Reports Server (NTRS)

    Nordtvedt, K. L., Jr.

    1972-01-01

    Review of historical and recent experiments which speak in favor of a post-Newtonian relativistic gravitational theory. The topics include the foundational experiments, metric theories of gravity, experiments designed to differentiate among the metric theories, and tests of Machian concepts of gravity. It is shown that the metric field for any metric theory can be specified by a series of potential terms with several parameters. It is pointed out that empirical results available up to date yield values of the parameters which are consistent with the prediction of Einstein's general relativity.

  13. Status of MICE, the international Muon Ionization Cooling Experiment

    NASA Astrophysics Data System (ADS)

    Bross, Alan D.; MICE Collaboration

    2012-08-01

    The Muon Ionization Cooling Experiment (MICE) will demonstrate transverse muon ionization cooling and is thus a strategic R&D project for future muon facilities. It is under development at the Rutherford Appleton Laboratory in the United Kingdom.

  14. Goals and Status of the NASA Juncture Flow Experiment

    NASA Technical Reports Server (NTRS)

    Rumsey, Christopher L.; Morrison, Joseph H.

    2016-01-01

    The NASA Juncture Flow experiment is a new effort whose focus is attaining validation data in the juncture region of a wing-body configuration. The experiment is designed specifically for the purpose of CFD validation. Current turbulence models routinely employed by Reynolds-averaged Navier-Stokes CFD are inconsistent in their prediction of corner flow separation in aircraft juncture regions, so experimental data in the near-wall region of such a configuration will be useful both for assessment as well as for turbulence model improvement. This paper summarizes the Juncture Flow effort to date, including preliminary risk-reduction experiments already conducted and planned future experiments. The requirements and challenges associated with conducting a quality validation test are discussed.

  15. Status of the ALICE experiment at the LHC

    SciTech Connect

    Herrera Corral, G.

    2008-11-13

    The Large Hadron Collider will provide soon, beams of protons and collisions at high energy to the experiments. ALICE stands for A Large Ion Collider Experiment. It is one of the experiments at the Large Hadron Collider. ALICE will be dedicated to the study of heavy ion collisions. The main goal of ALICE is the observation of the transition of ordinary matter into a plasma of quarks and gluons. ALICE consists of 16 systems of detection. Two of them were designed and constructed in Mexico: i) The V0A detector, located at 3.2 mts. from the interaction point and ii) The cosmic ray detector on the top of the magnet. After a quick review of the LHC and the ALICE experiment we will focus on the description of these systems.

  16. USA/FBR program status FFTF operations startup experience

    SciTech Connect

    Moffitt, W.C.; Izatt, R.D.

    1981-06-01

    This paper gives highlights of the major Operations evaluations and operational results of the startup acceptance testing program and initiation of normal operating cycles for experiment irradiation in the FFTF. 33 figures. (DLC)

  17. Status of FNAL SciBooNE experiment

    SciTech Connect

    Nakajima, Yasuhiro; /Kyoto U.

    2007-12-01

    SciBooNE is a new experiment at FNAL which will make precision neutrino-nucleus cross section measurements in the one GeV region. These measurements are essential for the future neutrino oscillation experiments. We started data taking in the antineutrino mode on June 8, 2007, and collected 5.19 x 10{sup 19} protons on target (POT) before the accelerator shutdown in August. The first data from SciBooNE are reported in this article.

  18. [Evoked potentials in intracranial operations: current status and our experiences].

    PubMed

    Nau, H E; Hess, W; Pohlen, G; Marggraf, G; Rimpel, J

    1987-03-01

    Intraoperative neuromonitoring, especially evoked potential monitoring, has gained interest in recent years for both the anesthesiologist evaluating cerebral function and the neurosurgeon wishing to avoid neuronal lesions during intracranial operations. Before evoked potential monitoring can be introduced as a routine method of intraoperative management, experience with this method particularly in intensive care units, is imperative. We recorded evoked potentials with the Compact Four (Nicolet) and Basis 8000 (Schwarzer Picker International) computer systems. Preoperative derivations should be done with the same apparatus used intraoperatively and parameters of peri- and intraoperative derivations should not be changed. The patient's head must be fixed in a Mayfield clamp in order to avoid artefacts during trepanation. The possible artefacts due to apparatus, patient, or anesthesia are summarized in the tables. The derivations of evoked potentials should be supervised by a person who is not involved in the anesthesia or the surgical procedure; this condition may change in the future with full automatization of the recording technique and alarms. Good communication between surgeon, anesthesiologist, and neurophysiological assistant is a prerequisite. The modality is chosen in accordance with the affected neuronal system: visual-evoked potential (VEP) monitoring in the management of processes affecting the visual pathway, brain stem auditory-(BAER) and somatosensory-evoked potential (SSEP) monitoring in lesions affecting these pathways, in particular space-occupying lesions of the posterior fossa. VEP monitoring may be useful, but we observed alterations of the responses without changes in the level of anesthesia or manipulation of the visual pathways. In space-occupying processes of the cerebellopontine angle, BAER could not be developed in nearly all cases because the large underlying tumor had caused the disappearance of waves II-V. In these cases SSEP monitoring

  19. [Evoked potentials in intracranial operations: current status and our experiences].

    PubMed

    Nau, H E; Hess, W; Pohlen, G; Marggraf, G; Rimpel, J

    1987-03-01

    Intraoperative neuromonitoring, especially evoked potential monitoring, has gained interest in recent years for both the anesthesiologist evaluating cerebral function and the neurosurgeon wishing to avoid neuronal lesions during intracranial operations. Before evoked potential monitoring can be introduced as a routine method of intraoperative management, experience with this method particularly in intensive care units, is imperative. We recorded evoked potentials with the Compact Four (Nicolet) and Basis 8000 (Schwarzer Picker International) computer systems. Preoperative derivations should be done with the same apparatus used intraoperatively and parameters of peri- and intraoperative derivations should not be changed. The patient's head must be fixed in a Mayfield clamp in order to avoid artefacts during trepanation. The possible artefacts due to apparatus, patient, or anesthesia are summarized in the tables. The derivations of evoked potentials should be supervised by a person who is not involved in the anesthesia or the surgical procedure; this condition may change in the future with full automatization of the recording technique and alarms. Good communication between surgeon, anesthesiologist, and neurophysiological assistant is a prerequisite. The modality is chosen in accordance with the affected neuronal system: visual-evoked potential (VEP) monitoring in the management of processes affecting the visual pathway, brain stem auditory-(BAER) and somatosensory-evoked potential (SSEP) monitoring in lesions affecting these pathways, in particular space-occupying lesions of the posterior fossa. VEP monitoring may be useful, but we observed alterations of the responses without changes in the level of anesthesia or manipulation of the visual pathways. In space-occupying processes of the cerebellopontine angle, BAER could not be developed in nearly all cases because the large underlying tumor had caused the disappearance of waves II-V. In these cases SSEP monitoring

  20. SNS Ring Operational Experience and Power Ramp Up Status

    SciTech Connect

    Plum, Michael A

    2009-01-01

    The SNS Ring has now been operating for about 3.5 years, and our march continues to increase the beam power to the full design value of 1.4 MW. The Ring is a loss-limited machine, and in general the radioactivation levels are good, but there are some unanticipated hot spots that we are working to improve. High intensity collective effects such as space-charge and beam instability have had minimal impact on beam operations to date. The cross plane coupling issue in the ring to target beam transport line has been solved. We will also discuss the status of equipment upgrades in the high-energy beam transport beam line, the injection-dump beam transport line, the ring, and the ring-to-target beam transport line.

  1. Present developments and status of electron sources for high power gyrotron tubes and free electron masers

    NASA Astrophysics Data System (ADS)

    Thumm, M.

    1997-02-01

    Gyrotron oscillators are mainly used as high power mm-wave sources for start-up, electron cyclotron heating (ECH) and diagnostics of magnetically confined plasmas for controlled thermonuclear fusion research. 140 GHz (110 GHz) gyrotrons with output power Pout = 0.55 MW (0.93 MW), pulse length τ = 3.0 s (2.0 s) and efficiency η = 40% (38%) are commercially available. Total efficiencies around 50% have been achieved using single-stage depressed collectors. Diagnostic gyrotrons deliver Pout = 40 kW with τ = 40 μs at frequencies up to 650 GHz ( η≥4%). Recently, gyrotron oscillators have also been successfully used in materials processing, for example sintering of high performance, structural and functional ceramics. Such technological applications require gyrotrons with f≥24 GHz, Pout = 10-100 kW, CW, η≥30%. This paper reports on recent achievements in the development of very high power mm-wave gyrotron oscillators for long pulse or CW operation. In addition a short overview of the present development status of gyrotrons for technological applications, gyroklystron amplifiers, gyro-TWT amplifiers, cyclotron autoresonance masers (CARMs) and free electron masers (FEMs) is given. The most impressive FEM output parameters are: Pout = 2GW, τ = 20 ns, η = 13% at 140 GHz (LLNL) and Pout = 15 kW, τ = 20 μs, η = 5% in the range from 120 to 900 GHz (UCSB). In gyro-devices, magnetron injection guns (MIGs) operating in the temperature limited current regime have thus far been used most successfully. Diode guns as well as triode guns with a modulating anode are employed. Tests of a MIG operated under space-charge limited conditions have been not very successful. Electrostatic CW FEMs are driven by thermionic Pierce guns whereas pulsed high power devices employ many types of accelerators as drivers for example pulse-line accelerators, microtrons and induction or rf linacs, using field and photo emission cathodes.

  2. Status of selected neutrinoless ββ-decay experiments

    NASA Astrophysics Data System (ADS)

    Avignone, F. T.; Brodzinski, R. L.; Reeves, J. H.; Miley, H. S.

    1988-11-01

    A brief update is given on a number of ongoing Oν ββ-decay experiments. Progress is reported in background reduction, limits are given on the various modes of decay, and projections of potential sensitivity are made in some cases. In particular, a new result from the PNL-USC Oν ββ decay experiment yields a half-life of (3.2+2.2-1.2)×1021 y (1σ) for decay with the emission of a majoron. While a positive result is still observed, it is now statistically less significant. A new recently deep-mined Ge to decrease background cosmogenic radioactivity.

  3. Status of NuMI experiments: MINOS+ and NO$\

    SciTech Connect

    Coelho, João A.B.

    2015-03-01

    The NuMI beam at Fermilab has been upgraded and is now capable of producing a 700 kW neutrino beam. Two major long-baseline neutrino experiments, MINOS+ and NOνA, have started data collection in the new NuMI configuration. This paper describes the latest developments of MINOS+ and NOνA. MINOS+ constitutes a new phase of the MINOS experiment and will provide improved sensitivity to new physics phenomena with a higher energy beam. NOνA will take advantage of its off-axis position to deliver precise measurements of

  4. Mariner 9 celestial mechanics experiment - A status report.

    NASA Technical Reports Server (NTRS)

    Lorell, J.; Shapiro, I. I.

    1973-01-01

    There are two basic efforts in the Mariner 9 celestial mechanics experiment: the determination of the gravity field of Mars and the performance of a very precise test of the theory of general relativity. In addition, there are a number of astrodynamic constants that are being determined. All the analyses are based on the Mariner 9 radio tracking data.

  5. [The problem of artificial gravity: the present status and possible approaches].

    PubMed

    Kotovskaia, A R

    2008-01-01

    The author reviews the Russian and international literature on the potentialities of artificial gravity in extended piloted space flights, especially in view of the declared initiatives to set forth on exploration missions in the first part of this century. Physical deconditioning and loss of tolerance to the gravitational loads consistently have their effects on cosmonauts despite the large assortment of in-flight preventive procedures. Effectiveness of artificial gravity generated by the short-arm centrifuge (SAC) has been assessed in experiments simulating the physiological consequences of microgravity by immersion or HDT, and flown aboard the dedicated satellites. It is emphasized that all the data indiscriminately indicate effectiveness of SAC as a preventive and therapeutic instrument alleviating the negative effects of modeled microgravity. Open issues and research objectives are presented.

  6. National Criticality Experiments Research Center: Capability and Status

    SciTech Connect

    Hayes, David K.; Myers, William L.

    2012-07-12

    After seven years, the former Los Alamos Critical Experiments Facility (LACEF), or Pajarito Site, has reopened for business as the National Criticality Experiments Research Center (NCERC) at the Nevada National Security Site (NNSS). Four critical assembly machines (Comet, Planet, Flat-Top, and Godiva-IV) made the journey from Los Alamos to the NNSS. All four machines received safety system upgrades along with new digital control systems. Between these machines, systems ranging from the thermal through the intermediate to the fast spectrum may be assembled. Steady-State, transient, and super-prompt critical conditions may be explored. NCERC is the sole remaining facility in the United States capable of conducting general-purpose nuclear materials handling including the construction and operation of high-multiplication assemblies, delayed critical assemblies, and prompt critical assemblies. Reconstitution of the unique capabilities at NCERC ensures the viability of (1) The Nuclear Renaissance, (2) Stockpile Stewardship, and (3) and the next generation of criticality experimentalists.

  7. Status of the BNL muon (g-2) experiment

    NASA Astrophysics Data System (ADS)

    Miller, J. P.; Barkov, L. M.; Benante, J.; Brown, D. H.; Brown, H. N.; Bunce, G.; Carey, R. M.; Chertovskikh, A.; Cullen, J.; Cushman, P.; Danby, G. T.; Debevec, P. T.; Deng, H.; Deninger, W.; Dhawan, S. K.; Disco, A.; Druzhinin, V. P.; Duong, L.; Earle, W.; Endo, K.; Efstathiadis, E.; Farley, F. J. M.; Fedotovich, G. V.; Fei, X.; Geller, J.; Gerhaeuser, J.; Giron, S.; Grigorev, D. N.; Golubev, V. B.; Grosse Perdekamp, M.; Grossmann, A.; Haeberlen, U.; Hazen, E. S.; Hertzog, D. W.; Hirabayashi, H.; Hseuh, H.; Hughes, B. J.; Hughes, V. W.; Ichii, S.; Ishida, K.; Jackson, J. W.; Jia, L.; Jungmann, K.; Kawall, D.; Khazin, B. I.; Kindem, J.; Kinoshita, T.; Krienen, F.; Kurokawa, S.; Larsen, R.; Lee, Y. Y.; Logashenko, I.; Mapes, M.; McNabb, R.; Meng, W.; Merzliakov, Yu.; Miller, D.; Mizumachi, Y.; Monich, V.; Morse, W. M.; Orlov, Y.; Ouyang, J.; Pai, C.; Pearson, C.; Polk, I.; Polly, C.; Prigl, R.; zu Putlitz, G.; Rankowitz, S.; Redin, S. I.; Rind, O.; Roberts, B. L.; Ryskulov, N.; Sandberg, J.; Sato, T.; Sedykh, S.; Semertzidis, Y. K.; Serednyakov, S.; Shatunov, Yu. M.; Shutt, R.; Snydstrup, L.; Solodov, E.; Soukas, A.; Stillman, A.; Sulak, L. R.; Tallerico, T.; Tanaka, M.; Toldo, F.; Timmermans, C.; Trofimov, A.; Urner, D.; von Walter, P.; Winn, D.; Woodle, K.; Worstell, W. A.; Yamamoto, A.; Zimmerman, D.

    1997-05-01

    The muon (g-2) experiment at Brookhaven has just completed a 3-month run for checkout and initial data-taking. In the first two months beam was taken in a parasitic mode where one out of ten AGS pulses was delivered for commissioning of the beam line, quadrupoles, detectors, and data acquisition system. This was followed by four weeks of dedicated data collection. The main components of the experiment, which include the pion/muon beam line, the superconducting inflector, the superferric storage ring with its pulsed electric quadrupoles and magnetic field measurement system, and the detector system based on lead-scintillating fiber electron calorimeters, have been satisfactorily commissioned. The muon (g-2) precession frequency is clearly seen as a large signal. It is estimaed that over 25×106 decay positrons with energies greater than 1.5 GeV have been detected.

  8. STATUS OF THE NEUTRALIZED DRIFT COMPRESSION EXPERIMENT (NDCX-II)

    SciTech Connect

    Waldron, W.L.; Kwan, J.W.

    2011-04-21

    The Neutralized Drift Compression Experiment (NDCX-II) is an 11 M$ induction accelerator project currently in construction at Lawrence Berkeley National Laboratory for warm dense matter (WDM) experiments investigating the interaction of ion beams with matter at elevated temperature and pressure. The machine consists of a lithium injector, induction accelerator cells, diagnostic cells, a neutralized drift compression line, a final focus solenoid, and a target chamber. The induction cells and some of the pulsed power systems have been reused from the decommissioned Advanced Test Accelerator at Lawrence Livermore National Laboratory after refurbishment and modification. The machine relies on a sequence of acceleration waveforms to longitudinally compress the initial ion pulse from 600 ns to less than 1 ns in {approx} 12 m. Radial confinement of the beam is achieved with 2.5 T pulsed solenoids. In the initial hardware configuration, 50 nC of Li{sup +} will be accelerated to 1.25 MeV and allowed to drift-compress to a peak current of {approx}40 A. The project started in the summer of 2009. Construction of the accelerator will be completed in the fall of 2011 and will provide a worldwide unique opportunity for ion-driven warm dense matter experiments as well as research related to novel beam manipulations for heavy ion fusion drivers.

  9. The Lithium Tokamak eXperiment (LTX) - Status and Plans

    NASA Astrophysics Data System (ADS)

    Kaita, R.; Majeski, R.; Berzak, L.; Gray, T.; Kozub, T.; Kugel, H.; Strickler, T.; Timberlake, J.; Yoo, J.; Zakharov, L.; Ahn, J.; Doerner, R.; Maingi, R.; Soukhanovskii, V.

    2007-11-01

    The LTX is the first toroidal device with a fully non-recycling wall almost completely surrounding the plasma. Such a plasma- facing component (PFC) is expected to lead to a new plasma regime with flat Te profiles, and the LTX goal is to explore its confinement and stability. The LTX is a spherical tokamak designed to have R=40 cm, a=26 cm, Bt=3.4 kG, Ip=400 kA, Te=1 keV, and Ti=200 eV, for discharges of 100 ms or more. It contains a shell with four segments, each made of 0.375''-thick copper and a 0.0625''-thick stainless steel liner. A lithium layer, up to 100 nm thick, will be vapor deposited on the liner between shots. For a non- recycling PFC, the lithium will be kept chemically active with a shell temperature above the lithium melting point. The first tokamak experiments with large area liquid lithium PFC's used a toroidal liquid lithium limiter in the Current Drive eXperiment - Upgrade (CDX-U). To compare with CDX-U results, initial experiments will be performed with a toroidal liquid lithium ``pool'' in the lower half of the LTX shell. Assembly of LTX is complete, and preparations for plasma operations are in progress.

  10. E-Learning in Supplemental Educational Systems in Taiwan: Present Status and Future Challenges

    ERIC Educational Resources Information Center

    Zhang, Ke; Hung, Jui-Long

    2009-01-01

    As Taiwan's full-scale e-learning initiatives moved to the seventh year in 2009, the current status and challenges of e-learning development there are yet to be fully understood. Further extending Zhang and Hung's (2006) investigation on e-learning in all universities and colleges in Taiwan, this study investigated the after-school programs (ASPs)…

  11. The present status of geography education in boys' intermediate schools of Riyadh, Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Al-Gahtany, Abdulrahman Mohammed

    The purpose of this study was to describe the present status of geography education in boys' intermediate schools in Riyadh, Saudi Arabia as perceived by geography teachers and supervisors; that is, to investigate the objectives, content, methods of teaching, tools and resources that are available and used in classrooms, evaluation techniques, and problems encountered in the teaching of geography. To collect data from this representative sample population, a questionnaire was developed by the researcher specifically for this study. Questionnaire data was collected from 19 social studies supervisors and 213 geography teachers. Percentages, frequencies, means, and standard deviations were computed for each questionnaire item. Chi Square tests were applied to determine if any significant differences could be identified between the observed and expected responses of supervisors and teachers. Major findings of the study indicated that both supervisors and teachers tend to strongly support the identified geography objectives. Most teachers and supervisors also indicated that the current geography curriculum contains enough information about Saudi Arabia, the Arabic world, and the Islamic world. In addition, the also indicated that geography content promotes a sense of patriotism and cultural pride. Responses indicated that educators see deficiencies in the content: it does not focus sufficiently on current events nor on developing student skills such as research and technical skills like drawing maps. Lecture and discussion are the most commonly used strategies in the teaching of geography. Field trips, role-playing, scientific competitions, scientific games, solving problems, and individual learning are less commonly used. Teaching tools most commonly used are wall maps and earth globes, whereas the use of geographical transparencies, models, and instruments is not common. Most of the teachers do lot use computers in their teaching. Evaluation techniques depend

  12. The Status and Background Considerations of XMASS Experiment

    SciTech Connect

    Kim, Y. D.

    2007-03-28

    The XMASS project utilizes ultrapure liquid xenon and aims to detect pp and 7Be solar neutrinos by means of {nu}e+ e scattering and also the WIMP dark matter particles. It requires ultra-low background, less than 10-5 count/(keV kg day). By using a 100 kg prototype detector, we have confirmed its feasibility to realize low background and low threshold. We have begun to design an 800 kg liquid xenon detector mainly for a WIMP search experiment. In this report, Monte-Carlo simulations about the expected background rates are described.

  13. Status of the DAMIC Direct Dark Matter Search Experiment

    SciTech Connect

    Aguilar-Arevalo, A.; et al.

    2015-09-30

    The DAMIC experiment uses fully depleted, high resistivity CCDs to search for dark matter particles. With an energy threshold $\\sim$50 eV$_{ee}$, and excellent energy and spatial resolutions, the DAMIC CCDs are well-suited to identify and suppress radioactive backgrounds, having an unrivaled sensitivity to WIMPs with masses $<$6 GeV/$c^2$. Early results motivated the construction of a 100 g detector, DAMIC100, currently being installed at SNOLAB. This contribution discusses the installation progress, new calibration efforts near the threshold, a preliminary result with 2014 data, and the prospects for physics results after one year of data taking.

  14. Status of the Mu3e Experiment at PSI

    NASA Astrophysics Data System (ADS)

    Perrevoort, Ann-Kathrin

    2016-04-01

    The Mu3e experiment aims to search for the lepton-flavour violating decay μ+ → e+e+e- with a sensitivity to one signal decay in 1016 muon decays at a muon stopping rate of 2 × 109 muons/s. With currently available rates of 108 muons/s, a sensitivity on the branching ratio of 10-15 is the aim of the first phase. This will allow for tests of new physics models with enhanced branching ratios for lepton-flavour violating processes with an unprecedented precision. The experiment must be operated at very high muon rates all the while suppressing the background of the decay {μ ^ + } to {e^ + }{e^ - }{e^ + }{bar ν _μ }{ν _e} and accidental electron-positron combinations. Therefore, a tracking detector made of thin pixel sensors with additional scintillating fibres and tiles for precise time measurement will be built. The development of the subdetectors is ongoing while detector construction is still in preparation.

  15. Current Status of the Gasdynamic Mirror Fusion Propulsion Experiment

    NASA Technical Reports Server (NTRS)

    Emrich, William J., Jr.

    2002-01-01

    Nuclear fusion appears to be the most promising concept for producing extremely high specific impulse rocket engines. One particular fusion concept which seems to be particularly well suited for fusion propulsion applications is the gasdynamic mirror (GDM). An experimental GDM device has been constructed at the NASA Marshall Space Flight Center to provide an initial assessment of the feasibility of this type of propulsion system. An initial shakedown of the device is currently underway with initial experiments slated to occur in late 2001. This device would operate at much higher plasma densities and with much larger L/D ratios than previous mirror machines. The high L/D ratio minimizes to a large extent certain magnetic curvature effects which lead to plasma instabilities causing a loss of plasma confinement. The high plasma density results in the plasma behaving much more like a conventional fluid with a mean free path shorter than the length of the device. This characteristic helps reduce problems associated with 'loss cone' microinstabilities. The device has been constructed to allow a considerable degree of flexibility in its configuration thus permitting the experiment to grow over time without necessitating a great deal of additional fabrication.

  16. Status of Coherent Cherenkov Wakefield Experiment at UCLA

    SciTech Connect

    Cook, A. M.; Knyazik, A.; Rosenzweig, J. B.; Tikhoplav, R.; Travish, G.; Williams, O. B.

    2009-01-22

    Coherent Cherenkov radiation (CCR) wakefields are produced when a compressed electron beam travels along the axis of a hollow cylindrical dielectric tube. In a dielectric wakefield accelerator (DWA) these wakefields accelerate either a trailing electron bunch or the tail of the driving bunch, depending on the modal structure of the radiation. For an appropriate choice of dielectric structure geometry and beam parameters the device operates in a single-mode regime, producing sinusoidal wakefields with wavelengths in the THz range. We report on preliminary results of an experiment at UCLA studying the potential of a DWA structure to produce high-power, narrow-band THz radiation. First measurements include observation of 1 MW peak-power pulses of coherent broadband radiation from a compact dipole beam dump magnet.

  17. Status of National Spherical Torus Experiment Liquid Lithium Divertor

    NASA Astrophysics Data System (ADS)

    Kugel, H. W.; Viola, M.; Ellis, R.; Bell, M.; Gerhardt, S.; Kaita, R.; Kallman, J.; Majeski, R.; Mansfield, D.; Roquemore, A. L.; Schneider, H.; Timberlake, J.; Zakharov, L.; Nygren, R. E.; Allain, J. P.; Maingi, R.; Soukhanovskii, V.

    2009-11-01

    Recent NSTX high power divertor experiments have shown significant and recurring benefits of solid lithium coatings on plasma facing components to the performance of divertor plasmas in both L- and H- mode confinement regimes heated by high-power neutral beams. The next step in this work is the 2009 installation of a Liquid Lithium Divertor (LLD). The 20 cm wide LLD located on the lower outer divertor, consists of four, 80 degree sections; each section is separated by a row of graphite diagnostic tiles. The temperature controlled LLD structure consists of a 0.01cm layer of vacuum flame-sprayed, 50 percent porous molybdenum, on top of 0.02 cm, 316-SS brazed to a 1.9 cm Cu base. The physics design of the LLD encompasses the desired plasma requirements, the experimental capabilities and conditions, power handling, radial location, pumping capability, operating temperature, lithium filling, MHD forces, and diagnostics for control and characterization.

  18. Status of soft photons in experiment E855

    SciTech Connect

    Woody, C.; Lissauer, D. ); Gomez del Campo, J.; Ray, A.; Shapira, D.; Tincknell, M. ); Clark, R. ); Erd, C.; Schukraft, J.; Willis, W. )

    1990-01-01

    Experiment E855 was carried out at the AGS at Brookhaven National Laboratory to study soft photon production near center of mass rapidity Y{sub cm} {approximately} 0 in proton-nucleus collisions at 10 at 18 GeV/c. This was the first dedicated experiment to study this phenomenon at these lower energies. It is important to note that the related process of low mass dilepton pair production has been studied extensively at these energies and an excess signal of dileptons above known hadronic backgrounds has been firmly established. E855 was designed to measure photon production from P{sub t} {approximately} 5 MeV/c up to several GeV/c. A search will be made for an excess of soft photons in the P{sub t} region below the Jacobian peak from {pi}{sup 0} decays, above that which is expected from hadronic bremsstrahlung. Any observed signal will be correlated with the total charged multiplicity in the event in order to determine its production mechanism. This correlation can be used to distinguish purely hadronic sources of soft photons, such as mesons decays and bremsstrahlung, which vary linearly with the charged multiplicity, and a thermal source of soft photons which would exhibit a quadratic dependence on the charged multiplicity. In addition, E855 will measure low energy photons from nuclear decays which can be a background for measuring soft photons near Y{sub cm} {approximately} 0. These photons are also interesting from a nuclear physics point of view, since the spectrum of photons from nuclei excited by incident high energy protons gives a measure of the temperature of the excited nucleus and the amount of excitation energy which can be transferred to a nucleus in a high energy proton collision.

  19. Status of the TREK/E36 Experiment at J-PARC

    NASA Astrophysics Data System (ADS)

    Kohl, Michael; TREK/E36 Collaboration

    2015-04-01

    The TREK/E36 experiment will provide a precision test of lepton universality in the Ke 2 /Kμ 2 ratio to search for new physics beyond the Standard Model. Simultaneously it will search for light U(1) gauge bosons and sterile neutrinos below 300 MeV/c2, which could be associated with dark matter or explain established muon-related anomalies such as the muon anomalous magnetic moment and the proton radius puzzle. The experiment is scheduled to run in 2015 at the J-PARC K1.1BR kaon beamline. It uses a scintillating fiber target to stop a beam of up to 106 positive kaons per second. The kaon decay products are detected with a large-acceptance toroidal spectrometer capable of tracking charged particles with high resolution, combined with a photon calorimeter with large solid angle and redundant particle identification systems. An overview of the planned experiment and the current project status will be presented. This project has been supported by DOE Early Career Award DE-SC0003884.

  20. Undergraduate engineering student experiences: Comparing sex, gender and switcher status

    NASA Astrophysics Data System (ADS)

    Fergen, Brenda Sue

    This dissertation explores undergraduate engineering experiences, comparing men with women and switchers with non-switchers. Factors related to a chilly academic climate and gender-role socialization are hypothesized to contribute to variations in men's and women's academic experiences and persistence rates. Both quantitative and qualitative data are utilized in an effort to triangulate the findings. Secondary survey data, acquired as result of a 1992 Academic Environment Survey, were utilized to test the hypothesis that sex is the most important predictor (i.e., demographic variable) of perceptions of academic climate. Regression analyses show that sex by itself is not always a significant determinant. However, when sex and college (engineering vs. other) are combined into dummy variables, they are statistically significant in models where sex was not significant alone. This finding indicates that looking at sex differences alone may be too simplistic. Thirty personal interviews were conducted with a random stratified sample of undergraduate students from the 1993 engineering cohort. The interview data indicate that differences in childhood socialization are important. With regard to persistence, differences in socialization are greater for switchers vs. non-switchers than men vs. women. Thus, gender-role socialization does not appear to play as prominent a role in women's persistence as past literature would indicate. This may be due to the self-selection process that occurs among women who choose to pursue engineering. Other aspects of childhood socialization such as parents' level of educational and occupation, students' high school academic preparation and knowledge of what to expect of college classes appear to be more important. In addition, there is evidence that, for women, male siblings play an important role in socialization. There is also evidence that women engineering students at Midwestern University face a chilly academic climate. The factors which

  1. CURRENT STATUS OF THE G0 PARITY VIOLATION EXPERIMENT CARRIED OUT AT JEFFERSON LABORATORY

    SciTech Connect

    Bimbot, L.

    2010-12-01

    Among experiments looking for strangeness in nuclear systems, electron scattering parity-violation type experiments aim mainly at measuring the strange quark contributions to the form factors of the proton. They can be accessed by measuring asymmetry in longitudinally polarized electron elastic scattering on hydrogen. The parity-violating asymmetry is measured at the ~ 10-7 level of accuracy, and when combined with the electromagnetic form factors of the proton, the strange form factors can be determined. The full separation of form factors according to quark flavour requires measurements at forward angle on hydrogen and at backward angle on proton and deuteron. The experimental setups used for the G0 experiment in the two different configurations will be described. The status of the analysis and the current results will be presented and discussed in relation with other experiments past and planned. The G0 forward angle measurement(2) detected the recoil proton with a segmented detector covering, for one incident energy, different Q2 bins ranging from 0.1 to 1.0 (GeV/c)2. This measurement provided a linear combination of strange magnetic and strange electric form factors for each Q2. In the backward angle configuration, electrons were detected and just one Q2 value was covered at a given incident energy. Due to time limitation, only two cases have been studied: Q2 ~ 0.63 and 0.23 (GeV/c)2. These values were chosen to be directly comparable with results from other experiments. By combining backward and forward configuration measurements it is possible to extract separately the electric and the magnetic strange form factors. The measurements are complete. The analysis, still in progress, will be described. A few comments will also be made regarding some other aspects of physics accessible in simultaneous measurements: neutral current in N transition parity violation in inclusive - production and 2 contribution to elastic scattering.

  2. One surgeon's Army experience with "wound shock" from Pearl Harbor to the present.

    PubMed

    Hardaway, Robert M

    2009-09-01

    The Army has had extensive experience in the study and treatment of shock, beginning with the American Civil War and continuing to the present. This is the story of one Army surgeon's experience, both in research and treatment of shock, from Pearl Harbor to the present.

  3. The Present Status of Airship Construction, Especially of Airship-framing Construction

    NASA Technical Reports Server (NTRS)

    Ebner, Hans

    1938-01-01

    This work proposes to sketch, in broad outline, the status of airship construction in the various countries, at a time when commerce over great distances might be finally opened up to the airship through the performances of the "Graf Zeppelin." After a short historical review, a survey of the most important rigid and semirigid airships built since 1925, their differences and special problems, is made. In more detailed treatment, the framing construction of the more recent rigid airships and some especially interesting structural questions are investigated.

  4. GALS - setup for production and study of multinucleon transfer reaction products: present status

    NASA Astrophysics Data System (ADS)

    Zemlyanoy, S.; Zagrebaev, V.; Kozulin, E.; Kudryavtsev, Yu; Fedosseev, V.; Bark, R.; Janas, Z.

    2016-06-01

    This is a brief report on the current status of the new GAs cell based Laser ionization Setup (GALS) at Flerov Laboratory for Nuclear Reactions (FLNR) - JINR, Dubna. GALS is planned to exploit available beams from the U-400M cyclotron in low energy multi-nucleon transfer reactions to study exotic neutron-rich nuclei located in the "north-east" region of nuclear map. Products from 4.5 to 9 MeV/nucleon heavy-ion collisions, such as 136Xe on 208Pb, are to be captured in a gas cell and selectively laser-ionized in a sextupole (quadrupole) ion guide extraction system.

  5. Status of the NASA GMAO Observing System Simulation Experiment

    NASA Technical Reports Server (NTRS)

    Prive, Nikki C.; Errico, Ronald M.

    2014-01-01

    An Observing System Simulation Experiment (OSSE) is a pure modeling study used when actual observations are too expensive or difficult to obtain. OSSEs are valuable tools for determining the potential impact of new observing systems on numerical weather forecasts and for evaluation of data assimilation systems (DAS). An OSSE has been developed at the NASA Global Modeling and Assimilation Office (GMAO, Errico et al 2013). The GMAO OSSE uses a 13-month integration of the European Centre for Medium- Range Weather Forecasts 2005 operational model at T511/L91 resolution for the Nature Run (NR). Synthetic observations have been updated so that they are based on real observations during the summer of 2013. The emulated observation types include AMSU-A, MHS, IASI, AIRS, and HIRS4 radiance data, GPS-RO, and conventional types including aircraft, rawinsonde, profiler, surface, and satellite winds. The synthetic satellite wind observations are colocated with the NR cloud fields, and the rawinsondes are advected during ascent using the NR wind fields. Data counts for the synthetic observations are matched as closely as possible to real data counts, as shown in Figure 2. Errors are added to the synthetic observations to emulate representativeness and instrument errors. The synthetic errors are calibrated so that the statistics of observation innovation and analysis increments in the OSSE are similar to the same statistics for assimilation of real observations, in an iterative method described by Errico et al (2013). The standard deviations of observation minus forecast (xo-H(xb)) are compared for the OSSE and real data in Figure 3. The synthetic errors include both random, uncorrelated errors, and an additional correlated error component for some observational types. Vertically correlated errors are included for conventional sounding data and GPS-RO, and channel correlated errors are introduced to AIRS and IASI (Figure 4). HIRS, AMSU-A, and MHS have a component of horizontally

  6. Engineering Status of the Fusion Ignition Research Experiment (FIRE)

    SciTech Connect

    Philip J. Heitzenroeder; Dale Meade; Richard J. Thome

    2000-10-24

    FIRE is a compact, high field tokamak being studied as an option for the next step in the US magnetic fusion energy program. FIRE's programmatic mission is to attain, explore, understand, and optimize alpha-dominated plasmas to provide the knowledge necessary for the design of attractive magnetic fusion energy systems. This study began in 1999 with broad participation of the US fusion community, including several industrial participants. The design under development has a major radius of 2 m, a minor radius of 0.525 m, a field on axis of 10T and capability to operate at 12T with upgrades to power supplies. Toroidal and poloidal field magnets are inertially cooled with liquid nitrogen. An important goal for FIRE is a total project cost in the $1B range. This paper presents an overview of the engineering details which were developed during the FIRE preconceptual design study in FY99 and 00.

  7. A greenhouse experiment for the identification of spectral indices for crop water and nitrogen status assessment

    NASA Astrophysics Data System (ADS)

    Marino Gallina, Pietro; Bechini, Luca; Cabassi, Giovanni; Cavalli, Daniele; Chiaradia, Enrico Antonio; Corti, Martina; Ferrante, Antonio; Martinetti, Livia; Masseroni, Daniele; Morgutti, Silvia; Nocito, Fabio Francesco; Facchi, Arianna

    2015-04-01

    Improvements in crop production depend on the correct adoption of agronomic and irrigation management strategies. The use of high spatial and temporal resolution monitoring methods may be used in precision agriculture to improve the efficiency in water and nutrient input management, guaranteeing the environmental sustainability of agricultural productions. In the last decades, many indices for the monitoring of water or nitrogen status of crops were developed by using multispectral images and, more recently, hyperspectral and thermal images acquired by satellite of airborne platforms. To date, however, comprehensive studies aimed at identifying indices as independent as possible for the management of the two types of stress are still scarce in the literature. Moreover, the chemometric approach for the statistical analysis of the acquired images is not yet widely experienced in this research area. In this context, this work presents the set-up of a greenhouse experiment that will start in February 2015 in Milan (Northern Italy), which aims to the objectives described above. The experiment will be carried out on two crops with a different canopy geometry (rice and spinach) subjected to four nitrogen treatments, for a total of 96 pots. Hyperspectral scanner and thermal images will be acquired at four phenological stages. At each phenological phase, acquisitions will be conducted on one-fourth of the pots, in the first instance in good water conditions and, subsequently, at different time steps after the cessation of irrigation. During the acquisitions, measurements of leaf area index and biomass, chlorophyll and nitrogen content in the plants, soil water content, stomatal conductance and leaf water potential will be performed. Moreover, on leaf samples, destructive biochemical analysis will be conducted to evaluate the physiological stress status of crops in the light of different irrigation and nutrient levels. Multivariate regression analysis between the acquired

  8. Turner syndrome: review of clinical, neuropsychiatric, and EEG status: an experience of tertiary center.

    PubMed

    Saad, Khaled; Abdelrahman, Ahmed A; Abdel-Raheem, Yasser F; Othman, Essam R; Badry, Reda; Othman, Hisham A K; Sobhy, Karema M

    2014-03-01

    We reviewed the clinical, neuropsychiatric, and EEG status of 53 turner syndrome (TS) females, aged 3-16 years, in Assiut university hospitals, Upper Egypt. The diagnosis and care of patients with TS in Egypt is still in the developing stage. Hence this study was undertaken to review the details of patients with TS with respect to the pattern of cognitive, psychiatric, and motor dysfunction. We aimed to provide a comprehensive data about the experience of our center comparable to previous studies, which have been published in this field. This will contribute to a better definition of the neuropsychiatric features that may be specific to TS that allows early and better detection and management of these cases. We found FSIQ and verbal IQ that seem to be at a nearly normal level and a decreased performance IQ. ADHD and autistic symptoms were found in 20.70 and 3.77 % of our cohort, respectively. The motor performance in TS was disturbed, with some neurological deficits present in 17 % (reduced muscle tone and reduced muscle power). In addition, females with TS in our study exhibit social and emotional problems, including anxiety (5.66 %) and depression (11.30 %). The EEG results revealed abnormalities in seven patients (13.20 %). One patient presenting with generalized tonic-clonic seizures showed generalized epileptiform activity, and six patients presenting with intellectual disabilities showed abnormal EEG background activity.

  9. Social determinants of health: present status, unanswered questions, and future directions.

    PubMed

    Raphael, Dennis

    2006-01-01

    This article reviews the current status of theory and research concerning the social determinants of health. It provides an overview of current conceptualizations and evidence on the impact of various social determinants of health. The contributions of different disciplines--epidemiology, sociology, political economy, and the human rights perspective--to the field are acknowledged, but profound gaps persist in our understanding of the forces that drive the quality of various social determinants of health and why research is too infrequently translated into action. Many of these gaps in knowledge concern the political, economic, and social forces that make implementation of public policy agendas focused on strengthening the social determinants of health problematic. The author identifies the areas of inquiry needed to help translate knowledge into action.

  10. A subordinate status position increases the present value of financial resources for low 2D:4D men.

    PubMed

    Millet, Kobe; Dewitte, Siegfried

    2008-01-01

    It has been suggested that the ratio of the length of the 2nd and 4th fingers (digit ratio or 2D:4D) is related to prenatal testosterone with lower ratios thought to be influenced by higher prenatal testosterone levels. Accordingly, low 2D:4D has been associated to a number of fitness-related factors, such as high status in competitive sports and in music. Recent evidence suggests that 2D:4D is also related to economic decision making. We combine both streams of research in the present paper. In two studies we manipulated status in two different ways. We found that a subordinate position raises discount rates, consistent with the reasoning that the present utility of money is higher for men in this position. Moreover, the effect was more pronounced for men with a low 2D:4D. There was a significant negative relationship between 2D:4D and level of discounting in a subordinate status position, but no significant relationship emerged in the dominant status position. Our studies add evidence to the recent line of research associating digit ratio and economic decision making. Moreover, our studies show that future 2D:4D research should focus on plausible interactions between 2D:4D and context cues rather than on linear relations.

  11. Status of Neutron Beta Decay Asymmetry Studies from the UCNA Experiment

    NASA Astrophysics Data System (ADS)

    Phillips, David, II

    2013-04-01

    The UCNA experiment measures the neutron β decay asymmetry parameter A(E) using bottled polarized ultracold neutrons (UCN). UCN are produced from a pulsed spallation solid deuterium source coupled to the 800 MeV proton beam at LANSCE. The UCN spin states are selected via a 7 T polarizing field and an adiabatic fast passage spin flipper. The polarized UCN are then transported to a 1 T 2x2π spectrometer where the emitted electrons are measured. In the Standard Model, the leading order value of A(E), A0, is a function of the axial-vector to vector coupling ratio λ≡gA/gV, providing complementary data to the physics probed by measurements of the neutron lifetime τn. When taken together with τn, measurements of the beta decay asymmetry permit a nuclear structure independent determination of the CKM matrix element Vud. This talk presents an overview of the UCNA experiment, the status of the analysis of our 2011 dataset, the work performed in 2012 and the path forward.

  12. Status of proof-of-principle experiment for coherent electron cooling

    SciTech Connect

    Pinayev I.; Belomestnykh, S.; Bengtsson, J.; Ben-Zvi, I.; Elizarov, A. et al

    2012-05-20

    Coherent electron cooling (CEC) has a potential to significantly boost luminosity of high-energy, high-intensity hadron colliders. To verify the concept we conduct proof-of-the-principle experiment at RHIC. In this paper, we describe the current experimental setup to be installed into 2 o'clock RHIC interaction regions. We present current design, status of equipment acquisition and estimates for the expected beam parameters. We use a dogleg to merge the electron and ion beams. The ions 'imprint' their distribution into the electron beam via a space charge density modulation. The modulation is amplified in an FEL comprised of a 7-m long helical wiggler. The ions are co-propagating with electron beam through the FEL. The ion's average velocity is matched to the group velocity of the wave-packet of e-beam density modulation in the FEL. A three-pole wiggler at the exit of the FEL tune the phase of the wave-packet so the ion with the central energy experience the maximum of the e-beam density modulation, where electric field is zero. The time-of-flight dependence on ion's provides for the electrical field caused by the density modulation to reduce energy spread of the ion beam. The used electron beam is bent off the ion path and damped.

  13. Status of joint US/USSR experiments planned for the Cosmos '83 biosatellite mission

    NASA Technical Reports Server (NTRS)

    Souza, K. A.

    1982-01-01

    The plans and status of the fourth joint US/USSR biosatellite experiment, scheduled to be conducted in the last half of 1983, are discussed. These experiments will be conducted on board an unmanned Soviet spacecraft and will involve two restrained Rhesus monkeys and 10 pregnant rats, as well as a variety of small plant and radiation biology experiments. Three of the joint studies will use the monkeys for studies of biorhythms, calcium homeostasis, and the cardiovascular system. The fourth experiment will study rodent embryogenesis and neonatal behavior and development following in utero exposure to spaceflight. Specialized sensors and battery powered hardware have been designed, fabricated, and qualified for flight.

  14. Reward Experience, Socioeconomic Status, and Sex: Exploring Parameters of the Overjustification Effect.

    ERIC Educational Resources Information Center

    Schilling, Deanna E.

    The overjustification hypothesis predicts decreased intrinsic motivation when persons are paid to perform an interesting task. The factors of reward experience, socioeconomic status (SES), and sex are examined while testing conflicting predictions of the hypothesis and reinforcement theory. Children from grade 1 at two public elementary schools…

  15. Relationship of Age, Marital Status, and Work Experience of Community College Nursing Students to Grades.

    ERIC Educational Resources Information Center

    Frerichs, Marian L.

    To investigate differences in academic success due to age (younger or older than age 23), marital status, and nursing experience, a three-way analysis of variance was performed on the grade point averages of 1,435 female nursing students enrolled in 22 Associate Degree Nursing (ADN) programs in Illinois. The sample, representing over 90 percent of…

  16. Present status and plans for upgrading the Lujan neutron scattering center

    SciTech Connect

    Rhyne, James J

    2010-01-01

    The Lujan Center, part of the LANSCE accelerator complex at Los Alamos National Laboratory, operates a comprehensive neutron scattering facility for the U.S. Department of Energy that serves approximately 300 users per year. This paper will discuss the current instruments and status of the facility and also focus on the plans for a major upgrade of the Center including new instruments and enhancements to specific existing instruments. The instrument suite currently includes two reflectometers (one with full polarization), an engineering diffraction machine, a diffractometer specialized to pair-distribution analysis, 2 general purpose powder diffractometers, and 2 inelastic spectrometers. To complement these spectrometers, a full range of pressure, temperature, and magnetic field sample environments is available for users. As part of the planning for a forthcoming enhancement of Lujan Center, a series of workshops have been held over the past year to encourage user input to the design for new instruments as well as major upgrades of existing machines. Many of the planned facilities are designed to take advantage of the Lujan Center 20 Hz pulse repetition rate and cold source moderators, both of which are beneficial for high-resolution instruments using long neutron wavelengths.

  17. Individuals with hematological malignancies before undergoing chemotherapy present oxidative stress parameters and acute phase proteins correlated with nutritional status.

    PubMed

    Camargo, Carolina de Quadros; Borges, Dayanne da Silva; de Oliveira, Paula Fernanda; Chagas, Thayz Rodrigues; Del Moral, Joanita Angela Gonzaga; Durigon, Giovanna Steffanello; Dias, Bruno Vieira; Vieira, André Guedes; Gaspareto, Patrick; Trindade, Erasmo Benício Santos de Moraes; Nunes, Everson Araújo

    2015-01-01

    Hematological malignancies present abnormal blood cells that may have altered functions. This study aimed to evaluate nutritional status, acute phase proteins, parameters of cell's functionality, and oxidative stress of patients with hematological malignancies, providing a representation of these variables at diagnosis, comparisons between leukemias and lymphomas and establishing correlations. Nutritional status, C-reactive protein (CRP), albumin, phagocytic capacity and superoxide anion production of mononuclear cells, lipid peroxidation and catalase activity in plasma were evaluated in 16 untreated subjects. Main diagnosis was acute leukemia (n = 9) and median body mass index (BMI) indicated overweight (25.6 kg/m(2)). Median albumin was below (3.2 g/dL) and CRP above (37.45 mg/L) the reference values. Albumin was inversely correlated with BMI (r = -0.53). Most patients were overweight before the beginning of treatment and had a high CRP/albumin ratio, which may indicate a nutrition inflammatory risk. BMI values correlated positively with lipid peroxidation and catalase activity. A strong correlation between catalase activity and lipid peroxidation was found (r = 0.75). Besides the elevated BMI, these patients also have elevated CRP values and unexpected relations between nutritional status and albumin, reinforcing the need for nutritional counseling during the course of chemotherapy, especially considering the correlations between oxidative stress parameters and nutritional status evidenced here.

  18. Microwave Three-Wave Mixing Experiments for Chirality Determination: Current Status

    NASA Astrophysics Data System (ADS)

    Perez, Cristobal; Shubert, V. Alvin; Schmitz, David; Medcraft, Chris; Krin, Anna; Schnell, Melanie

    2015-06-01

    Microwave three-wave mixing experiments have been shown to provide a novel and sensitive way to generate and measure enantiomer-specific molecular signatures. The handedness of the sample can be obtained from the phase of the molecular free induction decay whereas the enantiomeric excess can be determined by the amplitude of the chiral signal. After the introduction of this technique by Patterson et al. remarkable improvements have been realized and experimental strategies for both absolute phase determination and enantiomeric excess have been presented. This technique has been also successfully implemented at higher microwave frequencies. Here we present the current status of this technique as well future directions and perspectives. This will be illustrated through our systematic study of chiral terpenes as well as preliminary results in molecular clusters. Patterson, D.; Schnell, M.; Doyle, J. M. Enantiomer-Specific Detection of Chiral Molecules via Microwave Spectroscopy. Nature 2013, 497, 475-477. Patterson, D.; Doyle, J. M. Sensitive Chiral Analysis via Microwave Three-Wave Mixing. Phys. Rev. Lett. 2013, 111, 023008. Shubert, V. A.; Schmitz, D.; Patterson, D.; Doyle, J. M.; Schnell, M. Identifying Enantiomers in Mixtures of Chiral Molecules with Broadband Microwave Spectroscopy. Angew. Chem. Int. Ed. 2014, 53, 1152-1155. Lobsiger, S.; Perez, C.; Evangelisti, L.; Lehmann, K. K.; Pate, B. H. Molecular Structure and Chirality Detection by Fourier Transform Microwave Spectroscopy. J. Phys. Chem. Lett. 2014, 6, 196-200.

  19. Present Status And First Results of the Final Focus Beam Line at the KEK Accelerator Test Facility

    SciTech Connect

    Bambade, P.; Alabau Pons, M.; Amann, J.; Angal-Kalinin, D.; Apsimon, R.; Araki, S.; Aryshev, A.; Bai, S.; Bellomo, P.; Bett, D.; Blair, G.; Bolzon, B.; Boogert, S.; Boorman, G.; Burrows, P.N.; Christian, G.; Coe, P.; Constance, B.; Delahaye, Jean-Pierre; Deacon, L.; Elsen, E.; /DESY /Valencia U., IFIC /KEK, Tsukuba /Beijing, Inst. High Energy Phys. /Savoie U. /Fermilab /Ecole Polytechnique /KEK, Tsukuba /Kyungpook Natl. U. /KEK, Tsukuba /Pohang Accelerator Lab. /Kyoto U., Inst. Chem. Res. /Savoie U. /Daresbury /Tokyo U. /Royal Holloway, U. of London /Kyungpook Natl. U. /Pohang Accelerator Lab. /Tokyo U. /KEK, Tsukuba /SLAC /University Coll. London /KEK, Tsukuba /SLAC /Royal Holloway, U. of London /KEK, Tsukuba /Tokyo U. /SLAC /Tohoku U. /KEK, Tsukuba /Tokyo U. /Pohang Accelerator Lab. /Brookhaven /SLAC /Oxford U., JAI /SLAC /Orsay /KEK, Tsukuba /Oxford U., JAI /Orsay /Fermilab /Tohoku U. /Manchester U. /CERN /SLAC /Tokyo U. /KEK, Tsukuba /Oxford U., JAI /Hiroshima U. /KEK, Tsukuba /CERN /KEK, Tsukuba /Oxford U., JAI /Ecole Polytechnique /SLAC /Oxford U., JAI /Fermilab /SLAC /Liverpool U. /SLAC /Tokyo U. /SLAC /Tokyo U. /KEK, Tsukuba /SLAC /CERN

    2011-11-11

    ATF2 is a final-focus test beam line which aims to focus the low emittance beam from the ATF damping ring to a vertical size of about 37 nm and to demonstrate nanometer level beam stability. Several advanced beam diagnostics and feedback tools are used. In December 2008, construction and installation were completed and beam commissioning started, supported by an international team of Asian, European, and U.S. scientists. The present status and first results are described.

  20. [Impact of present-day forms of organization of physical education on the health status of preschool children].

    PubMed

    Kuchma, V R; Vishnevskaia, T Iu; Makarova, A Iu

    2006-01-01

    During a natural hygienic experiment, the physical development, psychomotor activity, exercise performance, and readiness were evaluated in 6-year-old children, in whom physical education had been organized by routine and experimental programs, including health-improving swimming in the indoor pool of a preschool educational establishment. Exercises built up on the principle of plot-role playing games, by using the developing corrective exercises and psychological and pedagogical escort, were established to be highly effective. The proposed methods contribute to the timely harmonious development of a child, his movement characteristics, positively affect the neurofunctional status, by ensuring the optimum psychomotor development, and maintain a high exercise performance.

  1. Near-Real Time Data for Space Weather Analyses: Present Status and Future

    NASA Technical Reports Server (NTRS)

    Hesse, Michael; Pulkkinen, Antti; Zheng, Yihua; Maddox, Marlo H.; Kuznetsova, Maria M.

    2011-01-01

    Assessments of the present state and future evolution of the space environment heavily relies on timely access to appropriate environmental measurements. These, near real-time (nrt), measurements provide a direct assessment of local or remote space environment conditions, they contribute to a more global description of Space Weather parameters through assimilative models, and they provide essential input into forecasting models. Unlike meteorology, however, the provision of these data is not a mainstream activity in the sense that critical space environment data are often derived from research rather than operational sensors. In addition, space research is a relatively immature field, where SUbstantial gaps in our knowledge impede our ability to optimally use available data streams. In this presentation, we provide examples of presently employed nrt data streams and their utility. We further discuss challenges and opportunities associated with the present approach to space weather forecasting. Finally, an outlook toward the future will be presented.

  2. [Acute edematous encephalopathy presenting with refractory generalized status epilepticus: an autopsy case].

    PubMed

    Yamashita, M; Yamamoto, T; Yasuda, T

    2001-11-01

    A previously healthy, 29-year-old man developed generalized convulsion with disturbed consciousness 3 days after the flu-like symptoms. On the next day, his convulsion evolved into generalized status epilepticus (GSE) that was unresponsive to administration of various anticonvulsants. Then, intravenous anesthetic agents, including midazolam, propofol and vecuronium sodium, were continuously infused. During the following 9 days, despite of high-dose infusion of these anesthetic agents, his GSE could not be suppressed, and complex partial seizure with secondary generalization frequently occurred. The patient was comatose and mechanically ventilated, whereas the brainstem reflexes were preserved. Electroencephalogram revealed a diffuse slowing of the background activity and occasional focal spike and wave complexes with secondary generalization. Cerebrospinal fluid analysis showed pleocytosis and elevated protein concentration. Cranial CT scans obtained on day 8 demonstrated brain edema. On day 10, his GSE ceased with abolition of the brainstem reflexes, and he lapsed into brain death resulting from the progressive brain edema. Over the following six days, his systemic circulation gradually worsened, and he died on day 16. On postmortem examination, the brain was markedly edematous and showed the findings consistent with acute anoxic encephalopathy with extensive circulatory stasis. Mild gliosis was observed in the insular cortex, yet no evidence of inflammatory disease was found throughout the brain. This patient was characterized by acutely progressive severe brain edema without inflammatory changes, suggesting that his primary disease was acute toxic encephalopathy presumably induced by viral infection. His GSE was refractory and unresponsive to the intensive treatment with the intravenous anesthetic agents. This case epitomizes the difficulties in controlling refractory seizures in some patients with encephalopathy or encephalitis.

  3. Status of health and environmental research relative to direct coal liquefaction: 1976 to the present

    SciTech Connect

    Gray, R.H.; Cowser, K.E.

    1982-06-01

    This document describes the status of health and environmental research efforts, supported by the US Department of Energy (DOE), to assist in the development of environmentally acceptable coal liquefaction processes. Four major direct coal liquefaction processes are currently in (or have been investigated at) the pilot plant stage of development. Two solvent refined coal processes (SRC-I and -II), H-coal (a catalytic liquefaction process) and Exxon donor solvent (EDS). The Pacific Northwest Laboratory was assigned responsibility for evaluating SRC process materials and prepared comprehensive health and environmental effects research program plans for SRC-I and -II. A similar program plan was prepared for H-coal process materials by the Oak Ridge National Laboratory. A program has been developed for EDS process materials by Exxon Research and Engineering Co. The program includes short-term screening of coal-derived materials for potential health and ecological effects. Longer-term assays are used to evaluate materials considered most representative of potential commercial practice and with greatest potential for human exposure or release to the environment. Effects of process modification, control technologies and changing operational conditions on potential health and ecological effects are also being evaluated. These assessments are being conducted to assist in formulating cost-effective environmental research programs and to estimate health and environmental risks associated with a large-scale coal liquefaction industry. Significant results of DOE's health and environmental research efforts relative to coal liquefaction include the following: chemical characterization, health effects, ecological fate and effects, amelioration and risk assessment.

  4. Profile and correlates of functional status in elderly patients presenting at a primary care clinic in Nigeria

    PubMed Central

    Adebusoye, Lawrence A.; Ogunbode, Adetola M.; Akinyemi, Joshua O.; Adebayo, Ayodeji M.

    2015-01-01

    Background Assessing the functional status of elderly patients is central in measuring their health outcome. Little is known about the functional status of elderly patients attending our primary care clinic in Nigeria. Objective To assess the correlates of functional status in elderly patients presenting at the General Outpatient Clinic of the University College Hospital, Ibadan, Nigeria. Method A cross-sectional study of 360 randomly selected patients aged 60 years and above was undertaken to assess their functional status by scoring their basic activities of daily living (BADL) using the Modified Bathel Index. An interviewer-administered questionnaire was used to obtain the socio-demographic data, anthropometric measurements and morbidities of each patient. Results The mean age was 69.1 ± 6.6 years with a female-to-male ratio of 1.9: 1. The prevalence of overall functional disability (defined as when assistance was sought in the performance of at least one of the components of BADL) was 88.3%. The highest prevalence of functional disability was experienced in the area of personal hygiene and grooming (95.3%) and transferring from bed to chair (95.3%). Overall functional disability significantly increased with increasing age (χ2 for trend=14.004, p < 0.0001), living in a polygamous family unit (p = 0.025), and lack of formal education (p = 0.020). Conclusion Functional disability was high amongst the elderly in this setting. Age, education, and living in a polygamous type of family unit had significant influence on the functional status. High premium should, therefore, be placed on considering these factors in reducing functional disability in the elderly. PMID:26245617

  5. Present status of radioactive waste management of Romanian Electricity Authority (RENEL)

    SciTech Connect

    Barariu, G.

    1994-12-31

    The paper presents the development program concerning management of radioactive wastes including nuclear spent fuel which has been elaborated to cover the main topics connected with all foresseeble nuclear power objectives from Romania.

  6. Current status of multiple antigen-presenting peptide vaccine systems: Application of organic and inorganic nanoparticles

    PubMed Central

    2011-01-01

    Many studies are currently investigating the development of safe and effective vaccines to prevent various infectious diseases. Multiple antigen-presenting peptide vaccine systems have been developed to avoid the adverse effects associated with conventional vaccines (i.e., live-attenuated, killed or inactivated pathogens), carrier proteins and cytotoxic adjuvants. Recently, two main approaches have been used to develop multiple antigen-presenting peptide vaccine systems: (1) the addition of functional components, e.g., T-cell epitopes, cell-penetrating peptides, and lipophilic moieties; and (2) synthetic approaches using size-defined nanomaterials, e.g., self-assembling peptides, non-peptidic dendrimers, and gold nanoparticles, as antigen-displaying platforms. This review summarizes the recent experimental studies directed to the development of multiple antigen-presenting peptide vaccine systems. PMID:21861904

  7. Korean atomic bomb survivors' report on the present status and health of their children: a mail questionnaire survey.

    PubMed

    Jhun, Hyung-Joon; Ju, Young-Su; Kim, Jung-Bum; Kim, Jin-Kook

    2006-01-01

    A mail questionnaire survey on the present status and health of children of Korean survivors of the 1945 atomic bombing of Japan was conducted in 2004. In total, 1,115 Korean A-bomb survivors' reports on demographic factors and the health of their children (n = 4,079) were analysed. In 2004, 293 of their children were reported to have died and 3,786 children still living. Among the deceased children, the cause of death was unidentified in 64 per cent of cases. The most frequently reported cause of death was infectious disease (9.6%). Most of the deaths (51%) were reported to have occurred in children less than ten years old. The most frequently reported congenital disorders among living children were mental retardation (0.18%) and congenital bone disorders (0.18%). Further study and administrative support are needed to more accurately determine the status of Korean A-bomb survivors and their children.

  8. The Status of Graphical Presentation in Interior/Architectural Design Education

    ERIC Educational Resources Information Center

    Gurel, Meltem O.; Basa, Inci

    2004-01-01

    This article argues that interior/architectural design education favours a dominance of final presentation over the design process in the studio environment, particularly in the evaluation of a project. It suggests that the appeal of design juries for pleasant drawings, which may shift the emphasis from the project itself to its representation,…

  9. LO sources for 1-3 THz: present status and future prospective

    NASA Technical Reports Server (NTRS)

    Mehdi, Imran

    2003-01-01

    This talk will present an overview of the current technologies that are available for implementing local oscillator sources for 1-3 THz applications. Progress to date on specific components will be discussed in some detail. Outstanding issues and concerns regarding practical implementation of these new technologies will also be discussed.

  10. Status-Relevant Experiences and Conspicuous Consumption - the Moderating Role of Prenatal Androgen Exposure.

    PubMed

    Cornelissen, Gert; Palacios-Fenech, Javier

    2016-01-01

    In this paper we study consumers' interest in acquiring and displaying expensive luxury products. Based on recent insights in consumer psychology, which build on developments in evolutionary biology, we consider luxury products as "costly signals": wasteful and costly goods, whose purpose is to communicate one's biological fitness, and social status, to others. In line with previous research, we show that experiences that trigger mate attraction goals (Study 1: Exposure to others in bathing outfit) or status display goals (Study 2: Experiencing a vicarious victory of one's favorite sports team) can increase people's interest in luxury products. However, we demonstrate that some individuals are predictably more responsive to those experiences than others. We used a physiological measure (the proportion of the length of the index finger and ring finger of the right hand, 2D:4D) as a proxy for individual differences in exposure to prenatal androgens (i.e., testosterone). This measure has been related to dominant and competitive behavior later in life. We predict and find that individuals with a low 2D:4D (i.e., high exposure to prenatal androgens) were more responsive to the status-relevant experiences: they became more interested in luxury goods after these experiences. This was not the case for high 2D:4D individuals. PMID:27647206

  11. Status-Relevant Experiences and Conspicuous Consumption - the Moderating Role of Prenatal Androgen Exposure.

    PubMed

    Cornelissen, Gert; Palacios-Fenech, Javier

    2016-01-01

    In this paper we study consumers' interest in acquiring and displaying expensive luxury products. Based on recent insights in consumer psychology, which build on developments in evolutionary biology, we consider luxury products as "costly signals": wasteful and costly goods, whose purpose is to communicate one's biological fitness, and social status, to others. In line with previous research, we show that experiences that trigger mate attraction goals (Study 1: Exposure to others in bathing outfit) or status display goals (Study 2: Experiencing a vicarious victory of one's favorite sports team) can increase people's interest in luxury products. However, we demonstrate that some individuals are predictably more responsive to those experiences than others. We used a physiological measure (the proportion of the length of the index finger and ring finger of the right hand, 2D:4D) as a proxy for individual differences in exposure to prenatal androgens (i.e., testosterone). This measure has been related to dominant and competitive behavior later in life. We predict and find that individuals with a low 2D:4D (i.e., high exposure to prenatal androgens) were more responsive to the status-relevant experiences: they became more interested in luxury goods after these experiences. This was not the case for high 2D:4D individuals.

  12. Electrospun cellulose acetate nanofibers: the present status and gamut of biotechnological applications.

    PubMed

    Konwarh, Rocktotpal; Karak, Niranjan; Misra, Manjusri

    2013-01-01

    Cellulose acetate (CA) has been a material of choice for spectrum of utilities across different domains ranging from high absorbing diapers to membrane filters. Electrospinning has conferred a whole new perspective to polymeric materials including CA in the context of multifarious applications across myriad of niches. In the present review, we try to bring out the recent trend (focused over last five years' progress) of research on electrospun CA fibers of nanoscale regime in the context of developmental strategies of their blends and nanocomposites for advanced applications. In the realm of biotechnology, electrospun CA fibers have found applications in biomolecule immobilization, tissue engineering, bio-sensing, nutraceutical delivery, bioseparation, crop protection, bioremediation and in the development of anti-counterfeiting and pH sensitive material, photocatalytic self-cleaning textile, temperature-adaptable fabric, and antimicrobial mats, amongst others. The present review discusses these diverse applications of electrospun CA nanofibers. PMID:23318668

  13. Status of the proton and electron transfer lines for the AWAKE Experiment at CERN

    NASA Astrophysics Data System (ADS)

    Schmidt, J. S.; Bauche, J.; Biskup, B.; Bracco, C.; Doebert, S.; Goddard, B.; Gschwendtner, E.; Jensen, L. K.; Jones, O. R.; Mazzoni, S.; Meddahi, M.; Pepitone, K.; Petrenko, A.; Velotti, F. M.; Vorozhtsov, A.

    2016-09-01

    The AWAKE project at CERN is planned to study proton driven plasma wakefield acceleration with an externally injected electron beam. Therefore two transfer lines are being designed in order to provide the proton beam from the SPS and the electron beam from an RF gun to the plasma cell. The commissioning of the proton line will take place in 2016 for the first phase of the experiment, which is focused on the self-modulation of a 12 cm long proton bunch in the plasma. The electron line will be added for the second phase of AWAKE in 2017, when the wakefield will be probed with an electron beam of 10-20 MeV/c. The challenge for these transfer lines lies in the parallel operation of the proton, electron and laser beam used to ionize the plasma and seed the self-modulation. These beams, of different characteristics, need to be synchronized and positioned for optimized injection conditions into the wakefield. This task requires great flexibility in the transfer line optics. The status of these designs will be presented in this paper.

  14. Status of the LBL experiment on femtosecond x-ray generation through 90{degree} Thomson scattering

    SciTech Connect

    Leemans, W.; Chattopadhyay, S.; Conde, M.; Glover, E.; Kim, K.J.; Schoenlein, R.; Shank, C.V.

    1994-06-01

    A status report on the generation of femtosecond X-ray pulses through 90{degrees} Thompson scattering is presented. The experiment involves a relativistic electron beam (tunable from 25--50 MeV) with a bunch length of 10 ps containing 1 {minus}2 nC, and a ultrashort pulse (50--200 fs), high power (4 TW) 0.8 {mu}m Ti:Al{sub 2}O{sub 3} laser system. Both beams are focussed down to about a 50 {mu}m waist size and intersect at 90{degrees}. The laser field acts as an electromagnetic undulator for the relativistic electron beam generating radiation upshifted by 2 {gamma}{sup 2} and a pulse length given by the transit time of the laser beam across the electron beam. For a 50 MeV electron beam we expect 10{sup 5} photons at 0.4 {angstrom} (10% bandwidth) in a cone angle of 6 mrad in a 170 fs pulse.

  15. The Euromet Project 772 on the Temperature Amplifier, from Its Proposal to the Present Status

    NASA Astrophysics Data System (ADS)

    Merlone, A.

    2008-10-01

    In February 2004, a Euromet project was discussed and an agreement was proposed among nine European national metrology institutes. The project is aimed at investigating the use of the Temperature Amplifier as a new temperature standard in the field of platinum resistance thermometry between the fixed points of Al and Ag. Since that time, several systems and devices have been studied, developed, manufactured, and assembled at INRiM. New gas-controlled heat pipes were manufactured taking into account the experience with devices acquired in previous years. An innovative pressure controller was studied and built for the purpose; the relevant electronic components were developed and fabricated by INRiM. Dedicated furnaces were designed and assembled, together with all the proper cooling lines. Control and acquisition software was also developed at INRiM. Some of those components have been tested and characterized both at the Italian (INRiM) and the French (LNE-INM/CNAM) Institutes of Metrology. This article describes the innovative devices dedicated to this project together with the first test results. The main results are also summarized, together with the descriptions of the plans for future project advances that will involve the other participating institutes.

  16. Status of health and environmental research relative to coal gasification 1976 to the present

    SciTech Connect

    Wilzbach, K.E.; Reilly, C.A. Jr.

    1982-10-01

    Health and environmental research relative to coal gasification conducted by Argonne National Laboratory, the Inhalation Toxicology Research Institute, and Oak Ridge National Laboratory under DOE sponsorship is summarized. The studies have focused on the chemical and toxicological characterization of materials from a range of process streams in five bench-scale, pilot-plant and industrial gasifiers. They also address ecological effects, industrial hygiene, environmental control technology performance, and risk assessment. Following an overview of coal gasification technology and related environmental concerns, integrated summaries of the studies and results in each area are presented and conclusions are drawn. Needed health and environmental research relative to coal gasification is identified.

  17. ISO WD 1856. Guideline for radiation exposure of nonmetallic materials. Present status

    NASA Astrophysics Data System (ADS)

    Briskman, B. A.

    In the framework of the International Organization for Standardization (ISO) activity we started development of international standard series for space environment simulation at on-ground tests of materials. The proposal was submitted to ISO Technical Committee 20 (Aircraft and Space Vehicles), Subcommittee 14 (Space Systems and Operations) and was approved as Working Draft 15856 at the Los-Angeles meeting (1997). A draft of the first international standard "Space Environment Simulation for Radiation Tests of Materials" (1st version) was presented at the 7th International Symposium on Materials in Space Environment (Briskman et al, 1997). The 2nd version of the standard was limited to nonmetallic materials and presented at the 20th Space Simulation Conference (Briskman and Borson, 1998). It covers the testing of nonmetallic materials embracing also polymer composite materials including metal components (metal matrix composites) to simulated space radiation. The standard does not cover semiconductor materials. The types of simulated radiation include charged particles (electrons and protons), solar ultraviolet radiation, and soft X-radiation of solar flares. Synergistic interactions of the radiation environment are covered only for these natural and some induced environmental effects. This standard outlines the recommended methodology and practices for the simulation of space radiation on materials. Simulation methods are used to reproduce the effects of the space radiation environment on materials that are located on surfaces of space vehicles and behind shielding. It was discovered that the problem of radiation environment simulation is very complex and the approaches of different specialists and countries to the problem are sometimes quite opposite. To the present moment we developed seven versions of the standard. The last version is a compromise between these approaches. It was approved at the last ISO TC20/SC14/WG4 meeting in Houston, October 2002. At a

  18. Overview and present status of the CMS Phase 1 pixel upgrade

    NASA Astrophysics Data System (ADS)

    Lipinski, M.

    2016-07-01

    During Run 2 of the LHC a significant luminosity increase to 2 ×1034cm-2s-1 is foreseen. As the innermost tracking device of CMS, the silicon pixel detector has to cope with large particle fluxes and radiation damage. To maintain the present high tracking efficiency, the current pixel detector will be replaced during an extended winter shutdown in 2016/2017. The design of the new detector is described, with a special focus on the construction and testing of the pixel modules.

  19. Irrigation Management in the Texas High Plains: Present Status, Challenges, and Opportunities (Invited)

    NASA Astrophysics Data System (ADS)

    Gowda, P. H.

    2013-12-01

    Evapotranspiration (ET) is an essential component of the water balance and a major consumptive use of irrigation water and precipitation on cropland. Any attempt to improve water use efficiency must be based on reliable estimates of ET for irrigation scheduling purposes. In the Texas High Plains, irrigation scheduling is implemented using lysimeter-based crop coefficients and reference ET data from the Texas High Plains ET Network. This presentation will discuss the current state of irrigation management in the Texas High Plains, knowledge gaps, ongoing developments, and role of remote sensing based regional ET mapping algorithms with respect to irrigated agriculture.

  20. Present and long-term pollution status of airborne copper in major urban environments

    NASA Astrophysics Data System (ADS)

    Kim, Ki-Hyun

    2014-09-01

    The concentrations of many harmful metals in air have been continuously decreasing around the world especially in North America and Western Europe, although deviations from such trend have been observed elsewhere such as East Asia. To help understand spatiotemporal factors governing the environmental behavior of hazardous metals, the concentrations of copper (Cu) in total suspended particulate (TSP) fractions were analyzed in the seven major cities in South Korea over a two decadal period (1991 through 2012). Unlike other metal species, there was no distinctive seasonal trend (e.g., spring/winter maximum and summer minimum) in the Cu levels in most South Korean cities. The long-term trend of Cu, if assessed by its annual mean values, recorded two contrasting trends for each decade: the earlier period (from 1991 to early 2000) is characterized by high variabilities with a maximum concentration of 243 ng m-3 (in 2003), while the later period showed an appreciable (several-fold) reduction to the latest (2012) available concentration level of 35.7 ng m-3. As such, the present Cu levels in Korea should approach those commonly seen in moderately clean urban environments elsewhere. The overall results suggest that South Korean regulatory efforts to control particulate matter (PM) emissions have greatly influenced the present Cu levels consistent with the observed temporal trends of airborne PM.

  1. [Present status of concurrent chemoreadiotherapy in squamous cell carcinoma of head and neck].

    PubMed

    Li, X M; Song, Q

    2016-07-01

    Head neck squamous cell carcinoma (HNSCC) is a common kind of malignancies in human body. For HNSCC in early stage, either surgical operation or radiotherapy can acquire satisfactory treatment results. However, any single treatment modality such as surgery alone or single radiation is insufficient to gain satisfactory tumor control. Multidisciplinary treatment (MDT) has become a mainstay and important therapeutic strategy in the management of HNSCC. Among various approaches in the MDT, concurrent chemoradiotheraqpy (CCR) constitutes a major progress, which implicates a lot in improving outcomes and organ preservations in managing HNSCC. In the present review, the history, mechanisms, indications along with side effects and drawbacks, and perspectives of CCR are to be described and discussed, in the hope of providing effective guidance for the domestic MDT, especially CCR in the management of HNSCC. PMID:27480307

  2. Dosimetric monitoring in Ukraine--present status and path to the future.

    PubMed

    Chumak, V; Boguslavskaya, A

    2007-01-01

    Despite wide use of nuclear energy and radiation sources in industry and medicine, there is no centralised dose accounting system in Ukraine; existing dosimetry services operate obsolete manual thermoluminescence dosemeter (TLD) readers and do not meet modern proficiency standards. Currently, dosimetric monitoring is required for approximately 42,000 occupationally exposed workers, including 9100 in medicine, 17,000 employees of nuclear power plants and approximately 16,000 workers dealing with other sources of occupational exposure. This article presents the plan of elaboration of the United System for monitoring and registration of individual doses which has the aim of harmonisation of individual monitoring in Ukraine through securing methodical unity; scientific and methodological guidance of individual dosimetric control; procurement of common technical policy regarding nomenclature and operation of instrumentation; implementation of quality assurance programmes; development and support of information infrastructure, in particular operation of the national registry of individual doses; training and certification of personnel engaged in the system of individual dosimetric monitoring.

  3. The Alaska minerals industry: Present status and prospects for expanded ties with Asia

    SciTech Connect

    Dorian, J.P.; Slivkoff, J.; Henagan, D.L.; Caldwell, H.C. ); John Choon Kim; Aberle, W. )

    1991-01-01

    With the exception of Hawaii, Alaska, more than any other US state, must be concerned with its international role as well as its geopolitical position in the North Pacific. Alaskan exports enter the competitive markets of Asia, and opportunities exist for Alaskan-Asian industrial cooperation. In light of recent efforts to diversify and expand Alaska's economic base, government and industry leaders are assessing prospects for further developing Alaska's minerals industry and increasing Alaska's links with major Asian mineral producing and consuming countries. In addition to trade, Alaskan-Asian minerals cooperation is also possible in the form of financial investment and lending, joint ventures, and technology transfers. This paper evaluates the present conditions that characterize the Alaskan minerals industry, and identifies the many possibilities for increased cooperation with Asia.

  4. Can decision biases improve insurance outcomes? An experiment on status quo bias in health insurance choice.

    PubMed

    Krieger, Miriam; Felder, Stefan

    2013-06-01

    Rather than conforming to the assumption of perfect rationality in neoclassical economic theory, decision behavior has been shown to display a host of systematic biases. Properly understood, these patterns can be instrumentalized to improve outcomes in the public realm. We conducted a laboratory experiment to study whether decisions over health insurance policies are subject to status quo bias and, if so, whether experience mitigates this framing effect. Choices in two treatment groups with status quo defaults are compared to choices in a neutrally framed control group. A two-step design features sorting of subjects into the groups, allowing us to control for selection effects due to risk preferences. The results confirm the presence of a status quo bias in consumer choices over health insurance policies. However, this effect of the default framing does not persist as subjects repeat this decision in later periods of the experiment. Our results have implications for health care policy, for example suggesting that the use of non-binding defaults in health insurance can facilitate the spread of co-insurance policies and thereby help contain health care expenditure. PMID:23783222

  5. Can decision biases improve insurance outcomes? An experiment on status quo bias in health insurance choice.

    PubMed

    Krieger, Miriam; Felder, Stefan

    2013-06-19

    Rather than conforming to the assumption of perfect rationality in neoclassical economic theory, decision behavior has been shown to display a host of systematic biases. Properly understood, these patterns can be instrumentalized to improve outcomes in the public realm. We conducted a laboratory experiment to study whether decisions over health insurance policies are subject to status quo bias and, if so, whether experience mitigates this framing effect. Choices in two treatment groups with status quo defaults are compared to choices in a neutrally framed control group. A two-step design features sorting of subjects into the groups, allowing us to control for selection effects due to risk preferences. The results confirm the presence of a status quo bias in consumer choices over health insurance policies. However, this effect of the default framing does not persist as subjects repeat this decision in later periods of the experiment. Our results have implications for health care policy, for example suggesting that the use of non-binding defaults in health insurance can facilitate the spread of co-insurance policies and thereby help contain health care expenditure.

  6. Can Decision Biases Improve Insurance Outcomes? An Experiment on Status Quo Bias in Health Insurance Choice

    PubMed Central

    Krieger, Miriam; Felder, Stefan

    2013-01-01

    Rather than conforming to the assumption of perfect rationality in neoclassical economic theory, decision behavior has been shown to display a host of systematic biases. Properly understood, these patterns can be instrumentalized to improve outcomes in the public realm. We conducted a laboratory experiment to study whether decisions over health insurance policies are subject to status quo bias and, if so, whether experience mitigates this framing effect. Choices in two treatment groups with status quo defaults are compared to choices in a neutrally framed control group. A two-step design features sorting of subjects into the groups, allowing us to control for selection effects due to risk preferences. The results confirm the presence of a status quo bias in consumer choices over health insurance policies. However, this effect of the default framing does not persist as subjects repeat this decision in later periods of the experiment. Our results have implications for health care policy, for example suggesting that the use of non-binding defaults in health insurance can facilitate the spread of co-insurance policies and thereby help contain health care expenditure. PMID:23783222

  7. An Overview of Important Ethnomedicinal Herbs of Phyllanthus Species: Present Status and Future Prospects

    PubMed Central

    Sarin, Bharti; Martín, Juan Pedro; Mohanty, Aparajita

    2014-01-01

    The genus Phyllanthus consists of more than 1000 species, of which many are used as traditional medicines. The plant extracts have been used since ancient times, for treating hypertension, diabetes, hepatic, urinary, and sexual disorders, and other common ailments. Modern day scientific investigations have now confirmed pharmacognostic properties of Phyllanthus herbs. The phytochemicals attributing these medicinal properties have been identified in many of the Phyllanthus herbs. The morphologically similar herbs of Phyllanthus grow together and admixture of species during collection for manufacture of herbal medicines is quite common. Hence, along with pharmacognostic and phytochemical studies, appropriate protocols for correct identification of species are also important. As the use of these herbs as green medicines is becoming more popular, it is imperative to assess its genetic diversity and phylogenetic relatedness for future conservation strategies. This review is an attempt to present an overview of the existing studies on pharmacognostics, phytochemistry, species identification, and genetic diversity of Phyllanthus herbs and consequently (i) highlight areas where further research is needed and (ii) draw attention towards extending similar studies in underutilized but potentially important herbs such as P. maderaspatensis, P. kozhikodianus, P. rheedii, P. scabrifolius, and P. rotundifolius. PMID:24672382

  8. Present status and strategic plan for the stable isotope reference materials at the IAEA.

    NASA Astrophysics Data System (ADS)

    Assonov, Sergey; Groening, Manfred

    2016-04-01

    The presentation will give the overview of the stable isotope reference materials (SI-RMs) under distribution by the IAEA, its stable isotope laboratory and capacities related to material testing & production as well as future plans. Historically, most of the IAEA reference materials were produced and made available via collaborations with expert stable isotope laboratories worldwide. The IAEA plans include several directions as follows: • Maintaining the scale-defining SI-RMs at the highest level and introducing adequate replacements when needed; • Monitoring existing SI-RMs for any potential alteration(s) and of isotopic values assigned; • Identifying and then addressing the needs for new SI-RMs, with the priority to address the most critical applications (environmental and climate related applications, human health, food safety studies) and newly emerging analytical isotope techniques; • Performing all measurements aimed for characterisation of new SI-RMs and the corresponding uncertainty evaluation in accordance to the latest metrological concepts; • Promoting metrological approaches on traceability and uncertainty evaluation in every day practice of stable isotope measurements; • Expanding the IAEA capacities for SI-RMs by (i) planning a renewed laboratory at IAEA; (ii) enlarging collaboration with expert laboratories aimed to help IAEA in production and characterisation of new SI-RMs. These major directions will help to address the increasing demand for Stable Isotope Reference Materials.

  9. Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders.

    PubMed

    Yoo, Ji Youn; Kim, Sung Soo

    2016-03-01

    Metabolic disorders, including type 2 diabetes (T2DM) and cardiovascular disease (CVD), present an increasing public health concern and can significantly undermine an individual's quality of life. The relative risk of CVD, the primary cause of death in T2DM patients, is two to four times higher in people with T2DM compared with those who are non-diabetic. The prevalence of metabolic disorders has been associated with dynamic changes in dietary macronutrient intake and lifestyle changes over recent decades. Recently, the scientific community has considered alteration in gut microbiota composition to constitute one of the most probable factors in the development of metabolic disorders. The altered gut microbiota composition is strongly conducive to increased adiposity, β-cell dysfunction, metabolic endotoxemia, systemic inflammation, and oxidative stress. Probiotics and prebiotics can ameliorate T2DM and CVD through improvement of gut microbiota, which in turn leads to insulin-signaling stimulation and cholesterol-lowering effects. We analyze the currently available data to ascertain further potential benefits and limitations of probiotics and prebiotics in the treatment of metabolic disorders, including T2DM, CVD, and other disease (obesity). The current paper explores the relevant contemporary scientific literature to assist in the derivation of a general perspective of this broad area. PMID:26999199

  10. Proton electromagnetic form factors: present status and future perspectives at PANDA

    NASA Astrophysics Data System (ADS)

    Tomasi-Gustafsson, E.

    2015-05-01

    Data and models on electromagnetic proton form factors are reviewed, highlighting the contribution foreseen by the PANDA collaboration. Electromagnetic hadron form factors contain essential information on the internal structure of hadrons. Precise and surprising data have been obtained at electron accelerators, applying the polarization method in electron-proton elastic scattering. At electron-positron colliders, using initial state radiation, BABAR measured proton time-like form factors in a wide time-like kinematical region and the BESIII collaboration will measure very precisely proton and neutron form factors in the threshold region. In the next future an antiproton beam with momentum up to 15 GeV/c will be available at FAIR (Darmstadt). Measurements of the reaction p̅ + p → e+ + e- by the PANDA collaboration will contribute to the individual determination of electric and magnetic form factors in the time-like region of momentum transfer squared, as well as to their first determination in the unphysical region (below the kinematical threshold), through the reaction p̅ + p → e+ + e- + π0. From the discussion on feasibility studies at PANDA, we focus on the consequences of such measurements in view of an unified description of form factors in the full kinematical region. We present models which have the necessary analytical requirements and apply to the data in the whole kinematical region.

  11. Present Status of Lateral-Control Devices for use with Split Flaps, Special Report

    NASA Technical Reports Server (NTRS)

    Weick, Fred E.

    1933-01-01

    The increased use of split flaps for the dual purpose of reducing the landing speed and shortening the landing glide of airplanes has established as acute the problem of obtaining satisfactory lateral control to be used in conjunction with the flaps with out the sacrifice of any of the effectiveness of the flaps. A large amount of work is being done on this problem by various organizations and individuals. Several of the devices developed seem usable, some of them unquestionably so. The present paper attempts to summarize the most promising results obtained to date. Topics covered include ordinary ailerons, external ailerons, floating ailerons, upper-surface ailerons, and spoilers. Although the external ailerons above the trailing edge of the wing and the spoilers at the rear of the wing appear quite promising, it would seem that probably the most satisfactory immediate solution of the problem, including the obtaining of light and smoothly graduated control forces, would in most cases be obtained by the use of the arrangement in which the flap is retracted ahead of ordinary narrow-chord ailerons and is deflected to the rear as well as downward when in use.

  12. The present status and future growth of maintenance in US manufacturing: results from a pilot survey

    PubMed Central

    Jin, Xiaoning; Siegel, David; Weiss, Brian A.; Gamel, Ellen; Wang, Wei; Lee, Jay; Ni, Jun

    2016-01-01

    A research study was conducted (1) to examine the practices employed by US manufacturers to achieve productivity goals and (2) to understand what level of intelligent maintenance technologies and strategies are being incorporated into these practices. This study found that the effectiveness and choice of maintenance strategy were strongly correlated to the size of the manufacturing enterprise; there were large differences in adoption of advanced maintenance practices and diagnostics and prognostics technologies between small and medium-sized enterprises (SMEs). Despite their greater adoption of maintenance practices and technologies, large manufacturing organizations have had only modest success with respect to diagnostics and prognostics and preventive maintenance projects. The varying degrees of success with respect to preventative maintenance programs highlight the opportunity for larger manufacturers to improve their maintenance practices and use of advanced prognostics and health management (PHM) technology. The future outlook for manufacturing PHM technology among the manufacturing organizations considered in this study was overwhelmingly positive; many manufacturing organizations have current and planned projects in this area. Given the current modest state of implementation and positive outlook for this technology, gaps, future trends, and roadmaps for manufacturing PHM and maintenance strategy are presented. PMID:27525253

  13. Adolescent Health: Present Status and Its Related Programmes in India. Are We in the Right Direction?

    PubMed Central

    Sivagurunathan, C; Umadevi, R.; Rama, R.

    2015-01-01

    Adolescence is a phase of rapid growth and development during which physical, physiological and behavioural changes occur. They constitute more than 1.2 billion worldwide, and about 21% of Indian population. Morbidity and mortality occurring in this age group is mostly due to preventable causes. Young and growing children have poor knowledge and lack of awareness about physical and psychological changes that occurs during adolescence and the ill health affecting them. Existing Adolescent health programmes focus on rendering services like immunization, health education for sexual and reproductive health, nutritional education and supplementation, anemia control measures and counseling. Adolescent health programmes are fragmentary at present and there is no comprehensive programme addressing all the needs of adolescents. Access and availability of health care services are severely limited. Lack of accurate information, absence of proper guidance, parent’s ignorance, lack of skills and insufficient services from health care delivery system are the major barriers. Interventions should focus on providing psychological and mental health services and behaviour change communication towards leading a healthy lifestyle, restricting advertisement related to junk food products, awareness creation about reproductive and sexual health, educating parents to prevent early marriage, teenage pregnancy and to counsel their children on nutrition and reproductive health. Universal coverage of Adolescent friendly clinics is highly recommended. To be cost effective, all health services addressing adolescent should come under single programme. This review is intended to create awareness among the stakeholders about the importance of strengthening adolescent health services in order to meet their felt needs. PMID:25964884

  14. Present status of sensitive detector of reactor’s antineutrinos using scintillating detectors

    SciTech Connect

    Fajt, L.; Mamedov, F.; Přidal, P.; Špavorová, M.; Štekl, I.; Belov, V.; Egorov, V. G.; Fomina, M.; Kuznetsov, A.; Ponomarev, D.; Rozova, I.; Zhitnikov, I.; Burešová, H.

    2015-08-17

    In 2011, the reanalysis of the reactor antineutrinos spectra led to the formulation of the Reactor Antineutrino Anomaly (RAA) [1], which indicates the discrepancy between measured and expected antineutrino fluxes on short baselines. This discrepancy appears to favor the existence of the fourth “sterile” neutrino with |Δm{sup 2}|>1 eV{sup 2}. To confirm or reject this hypothesis a high sensitive antineutrino detector located close to the reactor is required. In addition to that such a detector could be used to online monitor the isotopic composition of the reactor core and to prevent illegal production and removal of{sup 239}Pu, which is the essential part of nuclear weapons. Detector DANSSino [2] already proved that even a compact antineutrino detector (∼ 1 m{sup 3}) based on polystyrene is capable of antineutrino detection in the close vicinity of a reactor core (∼ 10 m) with signal to background ratio about one. As a common activity between JINR Dubna and IEAP CTU a new prototype of detector (called S{sup 3}) has been proposed and is under construction. The construction design, selected results of Monte Carlo simulations and results of benchmark tests are presented.

  15. An overview of important ethnomedicinal herbs of Phyllanthus species: present status and future prospects.

    PubMed

    Sarin, Bharti; Verma, Nidhi; Martín, Juan Pedro; Mohanty, Aparajita

    2014-01-01

    The genus Phyllanthus consists of more than 1000 species, of which many are used as traditional medicines. The plant extracts have been used since ancient times, for treating hypertension, diabetes, hepatic, urinary, and sexual disorders, and other common ailments. Modern day scientific investigations have now confirmed pharmacognostic properties of Phyllanthus herbs. The phytochemicals attributing these medicinal properties have been identified in many of the Phyllanthus herbs. The morphologically similar herbs of Phyllanthus grow together and admixture of species during collection for manufacture of herbal medicines is quite common. Hence, along with pharmacognostic and phytochemical studies, appropriate protocols for correct identification of species are also important. As the use of these herbs as green medicines is becoming more popular, it is imperative to assess its genetic diversity and phylogenetic relatedness for future conservation strategies. This review is an attempt to present an overview of the existing studies on pharmacognostics, phytochemistry, species identification, and genetic diversity of Phyllanthus herbs and consequently (i) highlight areas where further research is needed and (ii) draw attention towards extending similar studies in underutilized but potentially important herbs such as P. maderaspatensis, P. kozhikodianus, P. rheedii, P. scabrifolius, and P. rotundifolius. PMID:24672382

  16. Present status of ethics committees of the medical schools in Japan.

    PubMed

    Saito, Takao

    1991-12-01

    Present features and functions of ethics committees in 80 Japanese medical schools were surveyed through inquiries to those institutes by the author. Seventy nine schools have already started their own committees in each campus by the end of 1990, and the remaining one is preparing for its start in near future. The major role of the ethics committee may be said to roughly correspond to that of the Institutional Review Boards (IRB) in the USA, although a role of the hospital ethics committee has been played in addition to its proper functions in many schools. Among many problems two major drawbacks seem necessary to be removed urgently. The first one is an inappropriate composition of the committee in the majority of schools. More members from the outside of the campus, younger generations, and female reviewers should be added to the committee. The second point is the essentially closed review systems in most schools. The process of the review has not been effectively opened to the public yet, even in case in which no privacy of the patients or volunteers appears in the discussion. Several schools are preparing for opening now and the situation will be improved gradually. It was fortunate that the ethics committees in Japanese medical schools were founded by wills and efforts of members of each campus without having any suggestions, recommendations, or orders from the national government or other officials.

  17. Present status of sensitive detector of reactor's antineutrinos using scintillating detectors

    NASA Astrophysics Data System (ADS)

    Fajt, L.; Belov, V.; Burešová, H.; Egorov, V. G.; Fomina, M.; Kuznetsov, A.; Mamedov, F.; Ponomarev, D.; Přidal, P.; Rozova, I.; Špavorová, M.; Štekl, I.; Zhitnikov, I.

    2015-08-01

    In 2011, the reanalysis of the reactor antineutrinos spectra led to the formulation of the Reactor Antineutrino Anomaly (RAA) [1], which indicates the discrepancy between measured and expected antineutrino fluxes on short baselines. This discrepancy appears to favor the existence of the fourth "sterile" neutrino with |Δm2|>1 eV2. To confirm or reject this hypothesis a high sensitive antineutrino detector located close to the reactor is required. In addition to that such a detector could be used to online monitor the isotopic composition of the reactor core and to prevent illegal production and removal of239Pu, which is the essential part of nuclear weapons. Detector DANSSino [2] already proved that even a compact antineutrino detector (˜ 1 m3) based on polystyrene is capable of antineutrino detection in the close vicinity of a reactor core (˜ 10 m) with signal to background ratio about one. As a common activity between JINR Dubna and IEAP CTU a new prototype of detector (called S3) has been proposed and is under construction. The construction design, selected results of Monte Carlo simulations and results of benchmark tests are presented.

  18. ICRF Wall Conditioning: Present Status and Developments for Future Superconducting Fusion Machines

    SciTech Connect

    Lyssoivan, A.; Koch, R.; Van Eester, D.; Vervier, M.; Louche, F.; Lerche, E.; Ongena, J.; Paul, M. K.; Van Schoor, M.; Van Wassenhove, G.; Weynants, R.; Philipps, V.; Sergienko, G.; Esser, H. G.; Laengner, R.; Marchuk, O.; Schmitz, O.; Unterberg, B.; Rohde, V.

    2009-11-26

    ITER and future superconducting fusion machines need efficient wall conditioning techniques for routine operation in between shots in the presence of permanent high magnetic field for wall cleaning, surface isotope exchange and to control the in-vessel long term tritium retention. Ion Cyclotron Wall Conditioning (ICWC) based on the ICRF discharge is fully compatible and needs the presence of the magnetic field. The present paper focuses on the principal aspects of the ICWC discharge performance in large-size fusion machines: (i) neutral gas RF breakdown with conventional ICRF heating antennas, (ii) antenna coupling with low density ({approx}10{sup 17} m{sup -3}) RF plasmas and (iii) ICWC scenarios with improved RF plasma homogeneity in the radial and poloidal directions. All these factors were identified as crucial to achieve an enhanced conditioning effect (e.g. removal rates of selected 'marker' masses). All the observed effects are analyzed in terms of RF plasma wave excitation/absorption and compared with the predictions from 1-D RF full wave and 0-D RF plasma codes. Numerical modeling and empirical extrapolation from the existing machines give good evidence for the feasibility of using ICWC in ITER with the main ICRF antenna.

  19. An overview of important ethnomedicinal herbs of Phyllanthus species: present status and future prospects.

    PubMed

    Sarin, Bharti; Verma, Nidhi; Martín, Juan Pedro; Mohanty, Aparajita

    2014-01-01

    The genus Phyllanthus consists of more than 1000 species, of which many are used as traditional medicines. The plant extracts have been used since ancient times, for treating hypertension, diabetes, hepatic, urinary, and sexual disorders, and other common ailments. Modern day scientific investigations have now confirmed pharmacognostic properties of Phyllanthus herbs. The phytochemicals attributing these medicinal properties have been identified in many of the Phyllanthus herbs. The morphologically similar herbs of Phyllanthus grow together and admixture of species during collection for manufacture of herbal medicines is quite common. Hence, along with pharmacognostic and phytochemical studies, appropriate protocols for correct identification of species are also important. As the use of these herbs as green medicines is becoming more popular, it is imperative to assess its genetic diversity and phylogenetic relatedness for future conservation strategies. This review is an attempt to present an overview of the existing studies on pharmacognostics, phytochemistry, species identification, and genetic diversity of Phyllanthus herbs and consequently (i) highlight areas where further research is needed and (ii) draw attention towards extending similar studies in underutilized but potentially important herbs such as P. maderaspatensis, P. kozhikodianus, P. rheedii, P. scabrifolius, and P. rotundifolius.

  20. Adolescent health: present status and its related programmes in India. Are we in the right direction?

    PubMed

    Sivagurunathan, C; Umadevi, R; Rama, R; Gopalakrishnan, S

    2015-03-01

    Adolescence is a phase of rapid growth and development during which physical, physiological and behavioural changes occur. They constitute more than 1.2 billion worldwide, and about 21% of Indian population. Morbidity and mortality occurring in this age group is mostly due to preventable causes. Young and growing children have poor knowledge and lack of awareness about physical and psychological changes that occurs during adolescence and the ill health affecting them. Existing Adolescent health programmes focus on rendering services like immunization, health education for sexual and reproductive health, nutritional education and supplementation, anemia control measures and counseling. Adolescent health programmes are fragmentary at present and there is no comprehensive programme addressing all the needs of adolescents. Access and availability of health care services are severely limited. Lack of accurate information, absence of proper guidance, parent's ignorance, lack of skills and insufficient services from health care delivery system are the major barriers. Interventions should focus on providing psychological and mental health services and behaviour change communication towards leading a healthy lifestyle, restricting advertisement related to junk food products, awareness creation about reproductive and sexual health, educating parents to prevent early marriage, teenage pregnancy and to counsel their children on nutrition and reproductive health. Universal coverage of Adolescent friendly clinics is highly recommended. To be cost effective, all health services addressing adolescent should come under single programme. This review is intended to create awareness among the stakeholders about the importance of strengthening adolescent health services in order to meet their felt needs.

  1. Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders

    PubMed Central

    Yoo, Ji Youn; Kim, Sung Soo

    2016-01-01

    Metabolic disorders, including type 2 diabetes (T2DM) and cardiovascular disease (CVD), present an increasing public health concern and can significantly undermine an individual’s quality of life. The relative risk of CVD, the primary cause of death in T2DM patients, is two to four times higher in people with T2DM compared with those who are non-diabetic. The prevalence of metabolic disorders has been associated with dynamic changes in dietary macronutrient intake and lifestyle changes over recent decades. Recently, the scientific community has considered alteration in gut microbiota composition to constitute one of the most probable factors in the development of metabolic disorders. The altered gut microbiota composition is strongly conducive to increased adiposity, β-cell dysfunction, metabolic endotoxemia, systemic inflammation, and oxidative stress. Probiotics and prebiotics can ameliorate T2DM and CVD through improvement of gut microbiota, which in turn leads to insulin-signaling stimulation and cholesterol-lowering effects. We analyze the currently available data to ascertain further potential benefits and limitations of probiotics and prebiotics in the treatment of metabolic disorders, including T2DM, CVD, and other disease (obesity). The current paper explores the relevant contemporary scientific literature to assist in the derivation of a general perspective of this broad area. PMID:26999199

  2. A mainstay of functional food science in Japan--history, present status, and future outlook.

    PubMed

    Arai, S; Osawa, T; Ohigashi, H; Yoshikawa, M; Kaminogawa, S; Watanabe, M; Ogawa, T; Okubo, K; Watanabe, S; Nishino, H; Shinohara, K; Esashi, T; Hirahara, T

    2001-01-01

    The development of food science in the near future probably depends on the advance in functional food science, the concept of which was proposed first in Japan nearly 15 years ago. The new science has been internationally distributed and accepted as conceptually being beyond nutrition. In Japan, however, it traced a unique path of progress in the form of a product-driven rather than concept-driven science. Actually, a number of substances and products with potential for disease risk reduction rather than simply for health maintenance have been investigated for their body-modulating functions. Some of them have been applied in practice to the industrialization of functional foods in terms of "foods for specified health uses" legally defined by new legislation. A variety of sophisticated methods have been introduced as well, including the so-called "XYZ" evaluation system, database construction for assessment of the function, and even the DNA microarray technique. The Ministry of Agriculture, Forestry, and Fisheries (MAFF) and the Ministry of Health and Welfare (MHW) also commenced their scientific as well as political activity, with its spread to industries which almost simultaneously began to vigorously investigate functional food products for enlargement of the food market. With all of this as a background, the Japan Liaison of the International Union of Food Science and Technology (IUFoST) hold a function food science symposium on behalf of related scientific bodies including the Japan Section of the International Life Science Institute (ILSI). This paper is an overview compiled from 12 presentations made in the symposium, with the aim of internationally publicizing the activity of functional food science in Japan.

  3. Embryonic stem cells in companion animals (horses, dogs and cats): present status and future prospects.

    PubMed

    Tecirlioglu, R Tayfur; Trounson, Alan O

    2007-01-01

    Reproductive technologies have made impressive advances since the 1950s owing to the development of new and innovative technologies. Most of these advances were driven largely by commercial opportunities and the potential improvement of farm livestock production and human health. Companion animals live long and healthy lives and the greatest expense for pet owners are services related to veterinary care and healthcare products. The recent development of embryonic stem cell and nuclear transfer technology in primates and mice has enabled the production of individual specific embryonic stem cell lines in a number of species for potential cell-replacement therapy. Stem cell technology is a fast-developing area in companion animals because many of the diseases and musculoskeletal injuries of cats, dogs and horses are similar to those in humans. Nuclear transfer-derived stem cells may also be selected and directed into differentiation pathways leading to the production of specific cell types, tissues and, eventually, even organs for research and transplantaton. Furthermore, investigations into the treatment of inherited or acquired pathologies have been performed mainly in mice. However, mouse models do not always faithfully represent the human disease. Naturally occurring diseases in companion animals can be more ideal as disease models of human genetic and acquired diseases and could help to define the potential therapeutic efficiency and safety of stem cell therapies. In the present review, we focus on the economic implications of companion animals in society, as well as recent biotechnological progress that has been made in horse, dog and cat embryonic stem cell derivation.

  4. The impact of culture and minority status on women's experience of domestic violence.

    PubMed

    Kasturirangan, Aarati; Krishnan, Sandhya; Riger, Stephanie

    2004-10-01

    The influence of culture and ethnic background on women's experience of domestic violence has been explored in research only recently. Here the authors review research about the impact of culture and minority status in the United States on women's experience of domestic violence, considering family structure,immigration, acculturation, oppression, and community response. The authors encourage researchers and service providers to acknowledge the effects on women of sociopolitical dynamics, including racism, and to identify specific aspects of culture that are relevant to intimate partner abuse.

  5. The present status of biological effects of toxic metals in the environment: lead, cadmium, and manganese.

    PubMed

    Shukla, G S; Singhal, R L

    1984-08-01

    literature to identify the future theme of research work. The problem of metal toxicity becomes even more complex owing to simultaneous or successive exposure of the general population to different physical, chemical, biological, and psychological factors in the environment. The net toxic manifestations produced by multiple exposure should, therefore, be different from those produced by a single factor as the result of their additive, synergistic or antagonistic action. Even though a metal may not exist in sufficient amounts to cause any disability, the toxicity could result when a second factor is also present.(ABSTRACT TRUNCATED AT 400 WORDS)

  6. Status of Animal Experiments on International Space Station, and Animal Care Activities in Japan

    NASA Astrophysics Data System (ADS)

    Izumi, Ryutaro; Ishioka, Noriaki; Yumoto, Akane; Ito, Isao; Shirakawa, Masaki

    We would like to introduce animal experiments status on International Space Station (ISS) of Japan. Aquatic Habitat (AQH) was launched at 2012 July, by H-II Transfer Vehicle (HTV, ‘Kounotori’) from Tanegashima island in Japan, which could house small fish (Medaka, or Zebrafish) at most three months. First experiment using AQH was carried out for two months from Oct. 26, 2012, and second experiment would start from February, 2014. Mice housing hardware is now under development. For animal care activities, current topic in Japan is self-estimation for animal experiment status by each institute, and to open the result for public. JAXA conducted self-estimation of fiscal year 2011 (from 2011 April until 2012 March) for the first time, and would continue every fiscal year. JAXA already have its own animal care regulation, under animal care law and policy in Japan, and also referred COSPAR animal care guideline. And this year, JAXA made handbook for animal experiments in space (only Japanese).

  7. The reversed description-experience gap: Disentangling sources of presentation format effects in risky choice.

    PubMed

    Glöckner, Andreas; Hilbig, Benjamin E; Henninger, Felix; Fiedler, Susann

    2016-04-01

    Previous literature has suggested that risky choice patterns in general--and probability weighting in particular--are strikingly different in experience-based as compared with description-based formats. In 2 reanalyses and 3 new experiments, we investigate differences between experience-based and description-based decisions using a parametric approach based on cumulative prospect theory (CPT). Once controlling for sampling biases, we consistently find a reversal of the typical description-experience gap, that is, a reduced sensitivity to probabilities and increased overweighting of small probabilities in decisions from experience as compared with decisions from descriptions. This finding supports the hypothesis that regression to the mean effects in probability estimation are a crucial source of differences between both presentation formats. Further analyses identified task specific information asymmetry prevalent in gambles involving certainty as a third source of differences. We present a novel conceptualization of multiple independent sources of bias that contribute to the description-experience gap, namely sampling biases and task specific information asymmetry on the one hand, and regression to the mean effects in probability estimation on the other hand. PMID:26974209

  8. The reversed description-experience gap: Disentangling sources of presentation format effects in risky choice.

    PubMed

    Glöckner, Andreas; Hilbig, Benjamin E; Henninger, Felix; Fiedler, Susann

    2016-04-01

    Previous literature has suggested that risky choice patterns in general--and probability weighting in particular--are strikingly different in experience-based as compared with description-based formats. In 2 reanalyses and 3 new experiments, we investigate differences between experience-based and description-based decisions using a parametric approach based on cumulative prospect theory (CPT). Once controlling for sampling biases, we consistently find a reversal of the typical description-experience gap, that is, a reduced sensitivity to probabilities and increased overweighting of small probabilities in decisions from experience as compared with decisions from descriptions. This finding supports the hypothesis that regression to the mean effects in probability estimation are a crucial source of differences between both presentation formats. Further analyses identified task specific information asymmetry prevalent in gambles involving certainty as a third source of differences. We present a novel conceptualization of multiple independent sources of bias that contribute to the description-experience gap, namely sampling biases and task specific information asymmetry on the one hand, and regression to the mean effects in probability estimation on the other hand.

  9. The effects of age and experience on memory for visually presented music.

    PubMed

    Meinz, E J; Salthouse, T A

    1998-01-01

    Increased age is often associated with lower levels of performance in tests of memory for spatial information. The primary question in the current study was whether this relationship could be moderated as a function of one's relevant experience and/or knowledge. Stimulus materials consisted of short (7-11 note), visually presented musical melodies and structurally equivalent nonmusical stimuli. Participants (N = 128) were recruited from a wide range of age and experience levels. Although there were strong main effects of age and experience on memory for music, there was no evidence that the age-related differences in memory for these stimuli were smaller for individuals with moderate to large amounts of experience with music. PMID:9469173

  10. Experiments with Liquid Metal Walls: Status of the Lithium Tokamak Experiment

    SciTech Connect

    Kaita, Robert; Boyle, Dennis; Gray, Timothy; Granstedt, Erik; Hammett, Gregory; Jacobson, Craig M; Jones, Andrew; Kozub, Thomas; Kugel, Henry; Leblanc, Benoit; Logan, Nicholas; Lucia, Matthew; Lundberg, Daniel; Majeski, Richard; Mansfield, Dennis; Menard, Jonathan; Spaleta, Jeffrey; Strickler, Trevor; Timberlak, John

    2010-02-16

    Liquid metal walls have been proposed to address the first wall challenge for fusion reactors. The Lithium Tokamak Experiment (LTX) at the Princeton Plasma Physics Laboratory (PPPL) is the first magnetic confinement device to have liquid metal plasma-facing components (PFC's) that encloses virtually the entire plasma. In the Current Drive Experiment-Upgrade (CDX-U), a predecessor to LTX at PPPL, the highest improvement in energy confinement ever observed in Ohmically-heated tokamak plasmas was achieved with a toroidal liquid lithium limiter. The LTX extends this liquid lithium PFC by using a conducting conformal shell that almost completely surrounds the plasma. By heating the shell, a lithium coating on the plasma-facing side can be kept liquefied. A consequence of the low-recycling conditions from liquid lithium walls is the need for efficient plasma fueling. For this purpose, a molecular cluster injector is being developed. Future plans include the installation of a neutral beam for core plasma fueling, and also ion temperature measurements using charge-exchange recombination spectroscopy. Low edge recycling is also predicted to reduce temperature gradients that drive drift wave turbulence. Gyrokinetic simulations are in progress to calculate fluctuation levels and transport for LTX plasmas, and new fluctuation diagnostics are under development to test these predictions. __________________________________________________

  11. Abstraction, Re-Presentation, and Reflection, an Interpretation of Experience and Piaget's Approach.

    ERIC Educational Resources Information Center

    von Glasersfeld, Ernst

    In this paper, Piaget's theory is analyzed using Locke's philosophy. The first part, "Mental Experiences," describes the author's view (with a tentative interpretation of Piaget's position) of reflection, abstraction, re-presentation, and the use of symbols. The second part, "Piaget's Theory of Abstraction," has four sections: (1) "Form and…

  12. Progressive outer retinal necrosis syndrome: a comprehensive review of its clinical presentation, relationship to immune system status, and management.

    PubMed

    Austin

    2000-12-01

    Progressive outer retinal necrosis (PORN) syndrome is a form of the Varicella zoster virus (VZV) chorioretinitis found almost exclusively in people with the acquired immunodeficiency syndrome (AIDS). This destructive infection has an extremely rapid course that may lead to no light perception in affected eyes within days or weeks. Attempts at its treatment have had limited success. Rhegmatogenous retinal detachments often occur after the development of atrophic retinal holes, and silicone oil temponade has been found to be the most successful reattachment procedure. Unfortunately, cataract formation is common after such surgery. PORN needs to be differentiated from acute retinal necrosis (ARN) syndrome, a necrotizing retinitis that can also be caused by VZV. PORN and ARN are found at opposite ends of the spectrum of necrotizing herpetic retinopathies (NHR), where its clinical presentation depends upon immune system status. After a brief case presentation, the distinguishing clinical characteristics of PORN, its differentiation from ARN, attempts at its treatment, the role of the immune system status on its clinical appearance and treatment, and management of complications such as retinal detachment and subsequent cataracts are discussed.

  13. The isothermal dendritic growth experiment: Scientific status of a USMP-2 space flight experiment

    NASA Astrophysics Data System (ADS)

    Glicksman, M. E.; Koss, M. B.; Hahn, R. C.; Rojas, A.; Karthikeyan, M.; Winsa, E. A.

    1993-07-01

    The Isothermal Dendritic Growth Experiment (IDGE), to be performed on three of the USMP flights, starting with United States Microgravity Payload-2 (USMP-2), is designed to provide microgravity data on dendritic growth for a critical test of theory. Ground based test data using succinontrile (SCN), from both a flight capable growth chamber and a laboratory growth chamber, are compared to theoretical estimates of dendritic tip radii and velocities at several microgravity levels. The comparison shows that the data from the flight chamber are consistent with the historical data and that dendritic growth in a microgravity environment of 10-3 g0 or lower should exhibit significant differences from the dendritic growth of SCN at go.

  14. Adherence to preventive recommendations: experience of a cohort presenting for executive health care.

    PubMed

    Shippee, Nathan D; Mullan, Rebecca J; Nabhan, Mohammed; Kermott, Cindy A; Hagen, Philip T; Rhodes, Deborah J; Montori, Victor M; Murad, M Hassan

    2012-04-01

    Adherence to recommended preventive services and immunizations in adults is suboptimal and often associated with socioeconomic status, race, and access to care. The aim of this study is to evaluate adherence in a cohort without these barriers to ascertain realistically optimal adherence rates and to examine remaining barriers among relatively advantaged individuals. Specifically, it employed a sample of 6889 patients presenting for executive health care from 2005 to 2009. Adherence varied across colorectal cancer screening (79%), mammography (89%), cervical cancer screening (91%), tetanus immunization (82%), and pneumococcal vaccination (62%). Multivariate logistic regressions revealed that age, education, alcohol use concerns, and being married were positively associated with adherence to certain services. Individuals without the usual barriers to care have variable, less-than-ideal rates of adherence to preventive services, which correlate with some health behaviors and demographics. Understanding the predictors of adherence may inform quality improvement processes aimed at optimizing disease prevention.

  15. Design and development status of ETS-7, an RVD and space robot experiment satellite

    NASA Technical Reports Server (NTRS)

    Oda, M.; Inagaki, T.; Nishida, M.; Kibe, K.; Yamagata, F.

    1994-01-01

    ETS-7 (Engineering Test Satellite #7) is an experimental satellite for the in-orbit experiment of the Rendezvous Docking (RVD) and the space robot (RBT) technologies. ETS-7 is a set of two satellites, a chaser satellite and a target satellite. Both satellites will be launched together by NASDA's H-2 rocket into a low earth orbit. Development of ETS-7 started in 1990. Basic design and EM (Engineering Model) development are in progress now in 1994. The satellite will be launched in mid 1997 and the above in-orbit experiments will be conducted for 1.5 years. Design of ETS-7 RBT experiment system and development status are described in this paper.

  16. Aggressiveness and memory: subordinate crabs present higher memory ability than dominants after an agonistic experience.

    PubMed

    Kaczer, Laura; Pedetta, Silvia; Maldonado, Héctor

    2007-01-01

    A relationship between aggressiveness and memory has been proposed in several studies with different animal species. Here, we study this possibility in the crab Chasmagnathus granulatus, using the context-signal memory model (CSM) that involves an association between the learning context and a visual danger stimulus. Each experiment consisted of an agonistic phase and a memory one. During the former, matched pairs of male crabs were staged in two 10-min encounters and the dominant or subordinate condition of each member of the dyad was determined. During the memory phase, crabs were trained to acquire CSM and tested 24 h later. Results showed that the agonistic encounter, staged 48 h before the acquisition of CSM, can modulate memory according to the dominance condition of the fighter; in such a way that memory retention of subordinates results higher than that of dominants. By contrast, when the memory phase preceded the agonist one, forthcoming dominants and subordinates did not differ in their memory ability. The memory modulation would not be linked to a dominance status but to a persistent dominance relationship fully reconstructed in each encounter between the same opponents. Therefore, the crab's CSM would not depend directly on predetermined intrinsic properties, but on the outcome of the fight, which would be determined in turn by the relative aggressiveness of the fighters. The finding that the agonistic episode modulates memory opens the possibility of using this episodic interference to probe the function of diverse phases of CSM.

  17. Non-practice of breast self examination and marital status are associated with delayed presentation with breast cancer.

    PubMed

    Ghazali, Sumarni Mohd; Othman, Zabedah; Cheong, Kee Chee; Hock, Lim Kuang; Wan Mahiyuddin, Wan Rozita; Kamaluddin, Muhammad Amir; Yusoff, Ahmad Faudzi; Mustafa, Amal Nasir

    2013-01-01

    Delay in seeking treatment for breast cancer is a barrier to the early diagnosis and management of the disease, resulting in a poorer prognosis. We here estimated the prevalence of delayed presentation for breast cancer and identified possible influential sociodemographic factors in a cross-sectional study of 250 patients diagnosed with primary breast cancer at the Radiotherapy and Oncology Clinic in Kuala Lumpur Hospital. Data were collected by face-to-face interview using a structured questionnaire and from medical records. We examined associations between delayed presentation (presenting to a physician more than 3 months after self-discovery of a symptom) and sociodemographic characteristics, practice of breast self examination (BSE), history of benign breast disease, family history of breast cancer and type of symptom, symptom disclosure and advice from others to seek treatment using multiple logistic regression. Time from self-discovery of symptom to presentation ranged from tghe same day to 5 years. Prevalence of delayed presentation was 33.1% (95%CI: 27.4, 39.3). A significantly higher proportion of delayers presented with late stages (stage III/IV) (58.3% vs. 26.9%, p<0.001). Divorced or widowed women (OR: 2.23, 95% CI: 1.11, 4.47) had a higher risk of delayed presentation than married women and women who never performed breast self examination were more likely to delay presentation compared to those who regularly performed BSE (OR: 2.74, 95% CI: 1.33, 5.64). Our findings indicate that delayed presentation for breast cancer symptoms among Malaysian women is high and that marital status and breast self examination play major roles in treatment-seeking for breast cancer symptoms.

  18. Online Real-Time Presentation of Virtual Experiences for External Viewers.

    PubMed

    Ponto, Kevin; Shin, Hyun Joon; Kohlmann, Joe; Gleicher, Michael

    2012-01-01

    Externally observing the experience of a participant in a virtual environment is generally accomplished by viewing an egocentric perspective. Monitoring this view can often be difficult for others to watch due to unwanted camera motions that appear unnatural and unmotivated. We present a novel method for reducing the unnaturalness of these camera motions by minimizing camera movement while maintaining the context of the participant's observations. For each time-step, we compare the parts of the scene viewed by the virtual participant to the parts of the scene viewed by the camera. Based on the similarity of these two viewpoints we next determine how the camera should be adjusted. We present two means of adjustment, one which continuously adjusts the camera and a second which attempts to stop camera movement when possible. Empirical evaluation shows that our method can produce paths that have substantially shorter travel distances, are easier to watch and maintain the original observations of the participant's virtual experience.

  19. Capacity Value of Wind Plants and Overview of U.S. Experience (Presentation)

    SciTech Connect

    Milligan, M.

    2011-08-01

    This presentation provides an overview and summary of the capacity value of wind power plants, based primarily on the U.S. experience. Resource adequacy assessment should explicitly consider risk. Effective load carrying capability (ELCC) captures each generators contribution to resource adequacy. On their own, reserve margin targets as a percent of peak can't capture risks effectively. Recommend benchmarking reliability-based approaches with others.

  20. The daily commute from work to home: examining employees' experiences in relation to their recovery status.

    PubMed

    van Hooff, Madelon L M

    2015-04-01

    Sufficient recovery after daily effort expenditure at work is important to protect employee health and well-being. However, the role of commuting in the daily effort-recovery process is still not very well understood. The present study aimed to advance insight in this respect by examining if relaxation, detachment, mastery and stressful delays experienced during the commute from work to home affect employees' recovery status after returning home from work and at the end of the evening. Daily job demands were expected to moderate these effects. Serenity and (low) anxiety were included as indicators of employees' recovery status. Data were collected by means of a 5-day daily diary study (three measurements daily) among 76 participants from various industries. Multilevel analyses showed that relaxation was positively and stressful delays were negatively related to employees' recovery status after returning home from work but not to indicators of recovery at the end of the evening. For detachment, similar relations were found but only on days with high job demands. Mastery was not related to employees' recovery status. These findings enhance our insight in the daily effort-recovery cycle and underline the importance of promoting detachment (on demanding workdays) and relaxation on the way home from work. PMID:24124028

  1. The daily commute from work to home: examining employees' experiences in relation to their recovery status.

    PubMed

    van Hooff, Madelon L M

    2015-04-01

    Sufficient recovery after daily effort expenditure at work is important to protect employee health and well-being. However, the role of commuting in the daily effort-recovery process is still not very well understood. The present study aimed to advance insight in this respect by examining if relaxation, detachment, mastery and stressful delays experienced during the commute from work to home affect employees' recovery status after returning home from work and at the end of the evening. Daily job demands were expected to moderate these effects. Serenity and (low) anxiety were included as indicators of employees' recovery status. Data were collected by means of a 5-day daily diary study (three measurements daily) among 76 participants from various industries. Multilevel analyses showed that relaxation was positively and stressful delays were negatively related to employees' recovery status after returning home from work but not to indicators of recovery at the end of the evening. For detachment, similar relations were found but only on days with high job demands. Mastery was not related to employees' recovery status. These findings enhance our insight in the daily effort-recovery cycle and underline the importance of promoting detachment (on demanding workdays) and relaxation on the way home from work.

  2. Proposed program for and present status of the Geological Survey's investigation of domestic resources of radioactive raw materials

    USGS Publications Warehouse

    Bulter, A.P.; Killeen, P.L.; Page, G.B.; Rubey, W.W.

    1983-01-01

    This interim report is designed to show the present status of the Geological Survey's information and the parts of a comprehensive program necessary to improve our information about the raw material resources of uranium and thorium. Rarely in geologic work has it been necessary. to determine so completely a nation's resources of useful minerals in so brief a span of time. Ordinarily, information on mineral resources Is accumulated during a long period of years. However, uranium and thorium were suddenly thrust from a position of subsidiary economic interest into one of great strategic importance. Information concerning their occurrence must, therefore, be obtained as rapidly as reliable methods of investigation will permit. Accordingly the program must be at once comprehensive and carried out over an area more extensive than is usual in the search for and appraisal of most other mineral resources.

  3. Patients’ Experiences of Cancer Diagnosis as a Result of an Emergency Presentation: A Qualitative Study

    PubMed Central

    Black, Georgia; Sheringham, Jessica; Spencer-Hughes, Vicki; Ridge, Melanie; Lyons, Mairead; Williams, Charlotte; Fulop, Naomi; Pritchard-Jones, Kathy

    2015-01-01

    Introduction Cancers diagnosed following visits to emergency departments (ED) or emergency admissions (emergency presentations) are associated with poor survival and may result from preventable diagnostic delay. To improve outcomes for these patients, a better understanding is needed about how emergency presentations arise. This study sought to capture patients' experiences of this diagnostic pathway in the English NHS. Methods Eligible patients were identified in a service evaluation of emergency presentations and invited to participate. Interviews, using an open-ended biographical structure, captured participants' experiences of healthcare services before diagnosis and were analysed thematically, informed by the Walter model of Pathways to Treatment and NICE guidance in an iterative process. Results Twenty-seven interviews were conducted. Three typologies were identified: A: Rapid investigation and diagnosis, and B: Repeated cycles of healthcare seeking and appraisal without resolution, with two variants where B1 appears consistent with guidance and B2 has evidence that management was not consistent with guidance. Most patients’ (23/27) experiences fitted types B1 and B2. Potentially avoidable breakdowns in diagnostic pathways caused delays when patients were conflicted by escalating symptoms and a benign diagnosis given earlier by doctors. ED was sometimes used as a conduit to rapid testing by primary care clinicians, although this pathway was not always successful. Conclusions This study draws on patients' experiences of their diagnosis to provide novel insights into how emergency presentations arise. Through these typologies, we show that the typical experience of patients diagnosed through an emergency presentation diverges significantly from normative pathways even when there is no evidence of serious service failures. Consultations were not a conduit to diagnosis when they inhibited patients’ capacity to appraise their own symptoms appropriately and

  4. Technology and techniques for parity experiments at Mainz: Past, Present and Future

    NASA Astrophysics Data System (ADS)

    Diefenbach, Juergen

    2016-03-01

    For almost 20 years the Mainz accelerator facility MAMI delivered polarized electron beam to the parity violation experiment A4 that measured the contributions of strange sea quarks to the proton electromagnetic factors. Parity violation asymmetries were of the order of A ~5 ppm. Currently the A1 collaboration carries out single spin asymmetry measurements at MAMI (A ~20 ppm) to prepare for a measurement of neutron skin depth on lead (A ~1 ppm). For such high precision experiments active stabilization and precise determination of beam parameters like current, energy, position, and angle are essential requirements in addition to precision electron beam polarimetry. For the future P2 experiment at the planned superconducting accelerator MESA in Mainz the requirements for beam quality will be even higher. P2 will measure the weak mixing angle with 0.15 percent total uncertainty and, in addition, the neutron skin depth of lead as well as parity violation in electron scattering off 12C. A tiny asymmetry of only -0.03 ppm creates the needs to combine digital feedback with feedforward stabilizations along with new polarimetry developments like a hydro-Moller and a double-Mott polarimeter to meet the goals for systematic uncertainty. This talk gives an overview of our experience with polarimetry, analog feedbacks and compensation techniques for apparative asymmetries at the A4 experiment. It finally leads to the requirements and new techniques for the pioneering P2 experiment at MESA. First results from beam tests currently carried out at the existing MAMI accelerator, employing high speed analog/digital conversion and FPGAs for control of beam parameters, will be presented. Supported by the cluster of excellence PRISMA and the Deutsche Forschungsgemeinschaft in the framework of the SFB1044.

  5. Auditory presentation and synchronization in Adobe Flash and HTML5/JavaScript Web experiments.

    PubMed

    Reimers, Stian; Stewart, Neil

    2016-09-01

    Substantial recent research has examined the accuracy of presentation durations and response time measurements for visually presented stimuli in Web-based experiments, with a general conclusion that accuracy is acceptable for most kinds of experiments. However, many areas of behavioral research use auditory stimuli instead of, or in addition to, visual stimuli. Much less is known about auditory accuracy using standard Web-based testing procedures. We used a millisecond-accurate Black Box Toolkit to measure the actual durations of auditory stimuli and the synchronization of auditory and visual presentation onsets. We examined the distribution of timings for 100 presentations of auditory and visual stimuli across two computers with difference specs, three commonly used browsers, and code written in either Adobe Flash or JavaScript. We also examined different coding options for attempting to synchronize the auditory and visual onsets. Overall, we found that auditory durations were very consistent, but that the lags between visual and auditory onsets varied substantially across browsers and computer systems.

  6. Auditory presentation and synchronization in Adobe Flash and HTML5/JavaScript Web experiments.

    PubMed

    Reimers, Stian; Stewart, Neil

    2016-09-01

    Substantial recent research has examined the accuracy of presentation durations and response time measurements for visually presented stimuli in Web-based experiments, with a general conclusion that accuracy is acceptable for most kinds of experiments. However, many areas of behavioral research use auditory stimuli instead of, or in addition to, visual stimuli. Much less is known about auditory accuracy using standard Web-based testing procedures. We used a millisecond-accurate Black Box Toolkit to measure the actual durations of auditory stimuli and the synchronization of auditory and visual presentation onsets. We examined the distribution of timings for 100 presentations of auditory and visual stimuli across two computers with difference specs, three commonly used browsers, and code written in either Adobe Flash or JavaScript. We also examined different coding options for attempting to synchronize the auditory and visual onsets. Overall, we found that auditory durations were very consistent, but that the lags between visual and auditory onsets varied substantially across browsers and computer systems. PMID:27421976

  7. Status of the NGNP Fuel Experiment AGR-2 Irradiated in the Advanced Test Reactor

    SciTech Connect

    Blaine Grover

    2012-10-01

    The United States Department of Energy’s Next Generation Nuclear Plant (NGNP) Advanced Gas Reactor (AGR) Fuel Development and Qualification Program will be irradiating up to seven separate low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States, and will be irradiated over the next several years to demonstrate and qualify new TRISO coated particle fuel for use in high temperature gas reactors. The goals of the irradiation experiments are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of at least six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also have on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006 and was completed in November 2009. The second experiment (AGR-2), which utilized the same experiment design as well as control and monitoring systems as AGR-1, started irradiation in June 2010 and is currently scheduled to be completed in April 2013. The design of this experiment and support systems will be briefly discussed, followed by the progress and status of the experiment to date.

  8. Space Experiments with Particle Accelerators (SEPAC), status review, 23 September 1980

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The development responsibilities of SEPAC include: accelerator systems, diagnostic systems, power systems, dedicated experiment processor, interface unit, control panel, and all flight software. The operations of SEPAC, including automated experiments under DEP command control and SEPAC manual operations, are outlined. A diagram of the system configuration is presented.

  9. The shadow position sensors (SPS) formation flying metrology subsystem for the ESA PROBA-3 mission: present status and future developments

    NASA Astrophysics Data System (ADS)

    Focardi, M.; Noce, V.; Buckley, S.; O'Neill, K.; Bemporad, A.; Fineschi, S.; Pancrazzi, M.; Landini, F.; Baccani, C.; Capobianco, G.; Loreggia, D.; Casti, M.; Romoli, M.; Massone, G.; Nicolini, G.; Accatino, L.; Thizy, C.; Servaye, J. S.; Mechmech, I.; Renotte, E.

    2016-07-01

    PROBA-3 [1] [2] is a Mission of the European Space Agency (ESA) composed of two formation-flying satellites, planned for their joint launch by the end of 2018. Its main purposes have a dual nature: scientific and technological. In particular, it is designed to observe and study the inner part of the visible solar corona, thanks to a dedicated coronagraph called ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun), and to demonstrate the in-orbit formation flying (FF) and attitude control capability of its two satellites. The Coronagraph payload on-board PROBA-3 consists of the following parts: the Coronagraph Instrument (CI) with the Shadow Position Sensor (SPS) on the Coronagraph Spacecraft (CSC), the Occulter Position Sensor (OPSE) [3] [4] and the External Occulting (EO) disk on the Occulter Spacecraft (OSC). The SPS subsystem [5] is one of the main metrological devices of the Mission, adopted to control and to maintain the relative (i.e. between the two satellites) and absolute (i.e. with respect to the Sun) FF attitude. It is composed of eight micro arrays of silicon photomultipliers (SiPMs) [6] that shall be able to measure, with the required sensitivity and dynamic range as asked by ESA, the penumbral light intensity on the Coronagraph entrance pupil. With the present paper we describe the testing activities on the SPS breadboard (BB) and Development Model (DM) as well as the present status and future developments of this PROBA-3 metrological subsystem.

  10. The history, development and the present status of the radon measurement programme in the United States of America.

    PubMed

    George, A C

    2015-11-01

    The US radon measurement programme began in the late 1950s by the US Public Health Service in Colorado, New Mexico and Utah during the uranium frenzy. After the 1967 Congressional Hearings on the working conditions in uranium mines, the US Atomic Energy Commission (AEC) was asked to conduct studies in active uranium mines to assess the exposure of the miners on the Colorado Plateau and in New Mexico. From 1967 to 1972, the Health and Safety Laboratory of the US AEC in New York investigated more than 20 uranium mines for radon and radon decay product concentrations and particle size in 4 large uranium mines in New Mexico. In 1970, the US Environmental Protection Agency (EPA) was established and took over some of the AEC radon measurement activities. Between 1975 and 1978, the Environmental Measurements Laboratory of the US Department of Energy conducted the first detailed indoor radon survey in the USA. Later in 1984, the very high concentrations of radon found in Pennsylvania homes set the wheels in motion and gave birth to the US Radon Industry. The US EPA expanded its involvement in radon issues and assumed an active role by establishing the National Radon Proficiency Program to evaluate the effectiveness of radon measurement and mitigation methods. In 1998, due to limited resources EPA privatised the radon programme. This paper presents a personal perspective of past events and current status of the US radon programme. It will present an update on radon health effects, the incidence rate of lung cancer in the USA and the number of radon measurements made from 1988 to 2013 using short-term test methods. More than 23 million measurements were made in the last 25 y and as a result more than 1.24 million homes were mitigated successfully. It is estimated that <2 % of the radon measurements performed in the USA are made using long-term testing devices. The number of homes above the US action level of 148 Bq m(-3) (4 pCi l(-1)) may be ∼8.5 million because ∼50

  11. Present status and future outlook of selective metallization for electronics industry by laser irradiation to metal nanoparticles

    NASA Astrophysics Data System (ADS)

    Watanabe, Akira

    2015-03-01

    Recently an alternative to conventional methods based on vacuum processes such as evaporation or sputtering is desired to reduce the energy consumption and the environmental impact. Printed electronics has been developed as a one of the candidates, which is based on wet processes using soluble functional materials such as organic semiconductors, inorganic nanomaterials, organic-inorganic hybrids, and so on. Although inkjet printing has been studied widely as a core technology of printed electronics, the limitation of resolution is around 20 micrometer. The combination of the inkjet printing with other selective metallization process is necessary because the resolution of several micrometers is required in some optical and electrical devices. The laser processing has emerged as an attractive technique in microelectronics because of the fascinating features such as high resolution, high degree of flexibility to control the resolution and size of the micro-patterns, high speed, and a little environmental pollution. In this paper, the present status and future outlook of selective metallization for interconnection and the formation of transparent conductive film based on the laser processing using metal nanoparticles were reported. The laser beam irradiation to metal nanoparticles causes the fast and efficient sintering by plasmon resonance of metal nanoparticle, where the absorbed energy is confined in a nanoparticle and the nanoparticle acts as a nano-heater. The laser irradiation to metal nanoparticles was applied to the laser direct writing of metal wiring and micropatterns using silver and copper nanoparticles.

  12. Presentation and response timing accuracy in Adobe Flash and HTML5/JavaScript Web experiments.

    PubMed

    Reimers, Stian; Stewart, Neil

    2015-06-01

    Web-based research is becoming ubiquitous in the behavioral sciences, facilitated by convenient, readily available participant pools and relatively straightforward ways of running experiments: most recently, through the development of the HTML5 standard. Although in most studies participants give untimed responses, there is a growing interest in being able to record response times online. Existing data on the accuracy and cross-machine variability of online timing measures are limited, and generally they have compared behavioral data gathered on the Web with similar data gathered in the lab. For this article, we took a more direct approach, examining two ways of running experiments online-Adobe Flash and HTML5 with CSS3 and JavaScript-across 19 different computer systems. We used specialist hardware to measure stimulus display durations and to generate precise response times to visual stimuli in order to assess measurement accuracy, examining effects of duration, browser, and system-to-system variability (such as across different Windows versions), as well as effects of processing power and graphics capability. We found that (a) Flash and JavaScript's presentation and response time measurement accuracy are similar; (b) within-system variability is generally small, even in low-powered machines under high load; (c) the variability of measured response times across systems is somewhat larger; and (d) browser type and system hardware appear to have relatively small effects on measured response times. Modeling of the effects of this technical variability suggests that for most within- and between-subjects experiments, Flash and JavaScript can both be used to accurately detect differences in response times across conditions. Concerns are, however, noted about using some correlational or longitudinal designs online.

  13. Presentation and response timing accuracy in Adobe Flash and HTML5/JavaScript Web experiments.

    PubMed

    Reimers, Stian; Stewart, Neil

    2015-06-01

    Web-based research is becoming ubiquitous in the behavioral sciences, facilitated by convenient, readily available participant pools and relatively straightforward ways of running experiments: most recently, through the development of the HTML5 standard. Although in most studies participants give untimed responses, there is a growing interest in being able to record response times online. Existing data on the accuracy and cross-machine variability of online timing measures are limited, and generally they have compared behavioral data gathered on the Web with similar data gathered in the lab. For this article, we took a more direct approach, examining two ways of running experiments online-Adobe Flash and HTML5 with CSS3 and JavaScript-across 19 different computer systems. We used specialist hardware to measure stimulus display durations and to generate precise response times to visual stimuli in order to assess measurement accuracy, examining effects of duration, browser, and system-to-system variability (such as across different Windows versions), as well as effects of processing power and graphics capability. We found that (a) Flash and JavaScript's presentation and response time measurement accuracy are similar; (b) within-system variability is generally small, even in low-powered machines under high load; (c) the variability of measured response times across systems is somewhat larger; and (d) browser type and system hardware appear to have relatively small effects on measured response times. Modeling of the effects of this technical variability suggests that for most within- and between-subjects experiments, Flash and JavaScript can both be used to accurately detect differences in response times across conditions. Concerns are, however, noted about using some correlational or longitudinal designs online. PMID:24903687

  14. A flexible user-interface for audiovisual presentation and interactive control in neurobehavioral experiments.

    PubMed

    Noto, Christopher T; Mahzar, Suleman; Gnadt, James; Kanwal, Jagmeet S

    2013-01-01

    A major problem facing behavioral neuroscientists is a lack of unified, vendor-distributed data acquisition systems that allow stimulus presentation and behavioral monitoring while recording neural activity. Numerous systems perform one of these tasks well independently, but to our knowledge, a useful package with a straightforward user interface does not exist. Here we describe the development of a flexible, script-based user interface that enables customization for real-time stimulus presentation, behavioral monitoring and data acquisition. The experimental design can also incorporate neural microstimulation paradigms. We used this interface to deliver multimodal, auditory and visual (images or video) stimuli to a nonhuman primate and acquire single-unit data. Our design is cost-effective and works well with commercially available hardware and software. Our design incorporates a script, providing high-level control of data acquisition via a sequencer running on a digital signal processor to enable behaviorally triggered control of the presentation of visual and auditory stimuli. Our experiments were conducted in combination with eye-tracking hardware. The script, however, is designed to be broadly useful to neuroscientists who may want to deliver stimuli of different modalities using any animal model.

  15. Measuring Software Timing Errors in the Presentation of Visual Stimuli in Cognitive Neuroscience Experiments

    PubMed Central

    Garaizar, Pablo; Vadillo, Miguel A.; López-de-Ipiña, Diego; Matute, Helena

    2014-01-01

    Because of the features provided by an abundance of specialized experimental software packages, personal computers have become prominent and powerful tools in cognitive research. Most of these programs have mechanisms to control the precision and accuracy with which visual stimuli are presented as well as the response times. However, external factors, often related to the technology used to display the visual information, can have a noticeable impact on the actual performance and may be easily overlooked by researchers. The aim of this study is to measure the precision and accuracy of the timing mechanisms of some of the most popular software packages used in a typical laboratory scenario in order to assess whether presentation times configured by researchers do not differ from measured times more than what is expected due to the hardware limitations. Despite the apparent precision and accuracy of the results, important issues related to timing setups in the presentation of visual stimuli were found, and they should be taken into account by researchers in their experiments. PMID:24409318

  16. Experiences of social support among women presenting for obstetric fistula repair surgery in Tanzania

    PubMed Central

    Dennis, Alexis C; Wilson, Sarah M; Mosha, Mary V; Masenga, Gileard G; Sikkema, Kathleen J; Terroso, Korrine E; Watt, Melissa H

    2016-01-01

    Objective An obstetric fistula is a childbirth injury resulting in uncontrollable leakage of urine and/or feces and can lead to physical and psychological challenges, including social isolation. Prior to and after fistula repair surgery, social support can help a woman to reintegrate into her community. The aim of this study was to preliminarily examine the experiences of social support among Tanzanian women presenting with obstetric fistula in the periods immediately preceding obstetric fistula repair surgery and following reintegration. Patients and methods The study used a mixed-methods design to analyze cross-sectional surveys (n=59) and in-depth interviews (n=20). Results Women reported widely varying levels of social support from family members and partners, with half of the sample reporting overall high levels of social support. For women experiencing lower levels of support, fistula often exacerbated existing problems in relationships, sometimes directly causing separation or divorce. Many women were assertive and resilient with regard to advocating for their fistula care and relationship needs. Conclusion Our data suggest that while some women endure negative social experiences following an obstetric fistula and require additional resources and services, many women report high levels of social support from family members and partners, which may be harnessed to improve the holistic care for patients.

  17. Experiences of social support among women presenting for obstetric fistula repair surgery in Tanzania

    PubMed Central

    Dennis, Alexis C; Wilson, Sarah M; Mosha, Mary V; Masenga, Gileard G; Sikkema, Kathleen J; Terroso, Korrine E; Watt, Melissa H

    2016-01-01

    Objective An obstetric fistula is a childbirth injury resulting in uncontrollable leakage of urine and/or feces and can lead to physical and psychological challenges, including social isolation. Prior to and after fistula repair surgery, social support can help a woman to reintegrate into her community. The aim of this study was to preliminarily examine the experiences of social support among Tanzanian women presenting with obstetric fistula in the periods immediately preceding obstetric fistula repair surgery and following reintegration. Patients and methods The study used a mixed-methods design to analyze cross-sectional surveys (n=59) and in-depth interviews (n=20). Results Women reported widely varying levels of social support from family members and partners, with half of the sample reporting overall high levels of social support. For women experiencing lower levels of support, fistula often exacerbated existing problems in relationships, sometimes directly causing separation or divorce. Many women were assertive and resilient with regard to advocating for their fistula care and relationship needs. Conclusion Our data suggest that while some women endure negative social experiences following an obstetric fistula and require additional resources and services, many women report high levels of social support from family members and partners, which may be harnessed to improve the holistic care for patients. PMID:27660492

  18. MCTP Summer Research Internship Program. Research Presentation Day: Experience Mathematics and Science in the Real World

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This paper presents the summaries of the MCTP Summer Research Internship Program. Technological areas discussed include: Mathematical curriculum development for real world problems; Rain effects on air-water gas exchange; multi-ring impact basins on mars; developing an interactive multimedia educational cd-rom on remote sensing; a pilot of an activity for for the globe program; fossils in maryland; developing children's programming for the american horticultural society at river farm; children's learning, educational programs of the national park service; a study of climate and student satisfaction in two summer programs for disadvantaged students interested in careers in mathematics and science; the maryland governor's academy, integrating technology into the classroom; stream sampling with the maryland biological stream survey (MBSS); the imaging system inspection software technology, the preparation and detection of nominal and faulted steel ingots; event-based science, the development of real-world science units; correlation between anxiety and past experiences; environmental education through summer nature camp; enhancing learning opportunities at the Salisbury zoo; plant growth experiment, a module for the middle school classroom; the effects of proxisome proliferators in Japanese medaka embryos; development of a chapter on birth control and contraceptive methodologies as part of an interactive computer-based education module on hiv and aids; excretion of gentamicin in toadfish and goldfish; the renaissance summer program; and Are field trips important to the regional math science center?

  19. A review on immobilization of phosphate containing high level nuclear wastes within glass matrix--present status and future challenges.

    PubMed

    Sengupta, Pranesh

    2012-10-15

    Immobilization of phosphate containing high level nuclear wastes within commonly used silicate glasses is difficult due to restricted solubility of P(2)O(5) within such melts and its tendency to promote crystallization. The situation becomes more adverse when sulfate, chromate, etc. are also present within the waste. To solve this problem waste developers have carried out significant laboratory scale research works in various phosphate based glass systems and successfully identified few formulations which apparently look very promising as they are chemically durable, thermally stable and can be processed at moderate temperatures. However, in the absence of required plant scale manufacturing experiences it is not possible to replace existing silicate based vitrification processes by the phosphate based ones. A review on phosphate glass based wasteforms is presented here.

  20. Status and Perspective of the IGS Multi-GNSS Experiment (MGEX)

    NASA Astrophysics Data System (ADS)

    Steigenberger, Peter; Montenbruck, Oliver; Weber, Robert; Hugentobler, Urs

    2013-04-01

    Following three decades, during which the Global Positioning System GPS has evolved from a military navigation system into an indispensable tool for geodetic research and global monitoring of the Earth, the world of satellite navigation has experienced dramatic changes over the past years. With GLONASS, a second global navigation system has achieved a fully operational status, GPS is introducing modernized civil and encrypted navigation signals, and a variety of new navigation constellations are being built-up in Asia and Europe. These include BeiDou, which has recently opened a regional navigation service in the Asia-Pacific region, Galileo, which now has four satellites in orbit, as well as QZSS, which offers a unique set of signals and service features. In recognition of a rapidly changing GNSS landscape, the International GNSS Service (IGS) has initiated the Multi-GNSS Experiment (MGEX - http://igs.org/mgex) as a platform for early familiarization with emerging navigation systems and to pave the way for a full-featured use thereof in a future multi-GNSS service. As a first step, MGEX has promoted the build-up of a new global network of GNSS monitoring stations, each tracking at least one new constellation (Galileo, BeiDou, or QZSS) on top of GPS, GLONASS and SBAS. By the end of 2012, approximately 50 stations contribute offline and/or real-time data to the MGEX network. To facilitate introduction of new standards (specifically RINEX3 observation and navigation data formats), distinct data archives are used even for those MGEX stations jointly contributing to the legacy IGS. Building-up on the new multi-GNSS network, the generation of associated orbit and clock products has started in the second quarter of 2012. At this stage, only Galileo and QZSS products are offered by selected MGEX Analysis Centers, but the addition of BeiDou is expected in 2013 as the MGEX network expands and new Analysis Centers join the data processing effort. Despite remarkable progress

  1. The dosimetry system DS86 and the neutron discrepancy in Hiroshima--historical review, present status, and future options.

    PubMed

    Rühm, W; Kellerer, A M; Korschinek, G; Faestermann, T; Knie, K; Rugel, G; Kato, K; Nolte, E

    1998-12-01

    The historical development of the dosimetry systems for Hiroshima and Nagasaki is outlined from the time immediately after the A-bomb explosions to the publication of the dosimetry system DS86 in 1987, and the present status of the so-called Hiroshima neutron discrepancy is summarized. Several long-lived radionuclides are discussed with regard to their production by neutrons from the A-bomb explosions. With the exception of 63Ni, these radionuclides have not, up to now, been measured in samples from Hiroshima and Nagasaki. Two of them, 63Ni in copper samples and 39Ar in granite samples, were predominantly produced by fast neutrons. 63Ni can be determined by accelerator mass spectrometry with a gas-filled analyzing magnet. It should be measurable, in the near future, in copper samples up to 1500 m from the hypocenter in Hiroshima. 39Ar can be measured in terms of low-level beta-counting. This should be feasible up to a distance of about 1000 m from the hypocenter. Three radionuclides, 10Be, 14C, and 59Ni, were produced predominantly by thermal neutrons with smaller fractions due to the epithermal and fast neutrons, which contribute increasingly more at larger distances from the hypocenter. State-of-the-art accelerator mass spectrometry is likely to permit the determination of 10Be close to the hypocenter and of 14C up to a distance of about 1000 m. 59Ni should be detectable up to a distance of about 1000 m in terms of accelerator mass spectrometry with a gas-filled magnet. The measurements of 10Be, 14C, 39Ar, 59Ni -- and potentially of 131Xe -- can be performed in the same granitic sample that was already analyzed for 36Cl, 41Ca, 6Co, 152Eu, and 154Eu. This will provide extensive information on the neutron spectrum at the specified location, and similarly complete analyses can conceivably be performed on granite samples at other locations.

  2. The quality of reporting and publication status of vaccines trials presented at veterinary conferences from 1988 to 2003.

    PubMed

    Brace, Samantha; Taylor, Dan; O'Connor, Annette M

    2010-07-19

    Conference proceedings, although an importance source to learn about new interventions, are brief and not subject to external evaluation prior to publication. Studies in human medicine suggest that trial results from conference proceedings may be poorly reported. The primary objective of this study was to evaluate characteristics of veterinary vaccine studies published in conference proceedings. 154 cattle or swine vaccine trials presented at veterinary practitioner conferences held in the United States from 1988 to 2003 were the test base to evaluate the following: abstract-to-publication ratio, positive-outcome ratios, differences between proceeding and subsequent journal articles, and compliance with the CONSORT Statement extension for abstracts. The abstract-to-publication ratio was 5/89 for swine trials and 6/65 for cattle trials. The positive-outcome ratio for swine conference proceeding and journal articles was 57/89 and 4/5 respectively. The positive-outcome ratio for bovine conference proceeding and journal articles was 34/65 and 4/6 respectively. No major differences were found between conference proceedings and matching journal articles. Fewer than 10% of conference proceedings included: identification of the trials as randomized in the title, study design as field or challenge; the primary outcome; trial status; results for primary outcome; information about harms and funding source (2/89). When conference proceedings are subsequently published in journals; there is no significant difference in the data, however subsequent publication is uncommon. For many conference proceedings it would be difficult to assess the internal and external validity of the trial based on the information reported.

  3. Sequential prefrontal lobe volume changes and cognitive dysfunctions in children with Panayiotopoulos syndrome presenting with status epilepticus.

    PubMed

    Kanemura, Hideaki; Sano, Fumikazu; Ohyama, Tetsuo; Aoyagi, Kakuro; Sugita, Kanji; Aihara, Masao

    2015-05-01

    Panayiotopoulos syndrome (PS) is usually not associated with neurodevelopmental problems. However, neuropsychological impairments may also be present in at least some of the patients with PS. On the other hand, several degrees of neuronal damage due to status epilepticus (SE) may occur in the cortex. We prospectively measured frontal and prefrontal lobe volumes using three-dimensional magnetic resonance imaging (3D-MRI)-based volumetry in patients with PS with and without SE. Moreover, the neuropsychological outcome in relation to the presence of SE in children with PS is also discussed. We studied six patients with a final diagnosis of PS, including three cases with SE and cognitive impairments/behavioral problems (SE group) and three cases without SE (non-SE group). Serial 3D-MRI studies were performed five times (at onset of clinical symptoms and 1-4 years after onset) in both the SE and non-SE patients. All patients were studied with a set of Wechsler Intelligence Scale for Children, version III (WISC-III) or Wechsler Preschool and Primary Scale of Intelligence tests and the Kaufman Assessment Battery for Children (K-ABC). Growth of the frontal and prefrontal lobes was slightly decreased for some time after SE episodes in the SE patients. Moreover, the prefrontal-to-frontal lobe volume ratio was stagnant for some time after SE in the SE patients. The scores on the neuropsychological tests were decreased in the SE patients. Moreover, the average WISC and K-ABC scores in the SE group remained low and did not reach the levels of the initial examinations. Occurrence of SE in patients with PS at least in some patients may be associated with retarded prefrontal lobe growth, which was related to neuropsychological problems and ultimately, neuropsychological outcomes. Treatment management may be required to prevent SE as much as possible to achieve optimal prognosis in PS at least in some patients. PMID:25847347

  4. Acute mental status change as the presenting feature of adrenal insufficiency in a patient with autoimmune polyglandular syndrome type II and stroke

    PubMed Central

    Watson, Sara; Raj, Shekar; Eugster, Erica; Sanchez, Juan

    2014-01-01

    Primary adrenal insufficiency (AI) in children usually presents with non-specific symptoms such as fatigue, nausea, vomiting, and anorexia. Here, we report an unusual case of a 15 year old girl who presented with acute mental status change and was ultimately diagnosed with AI due to autoimmune polyglandular syndrome type II (APS2). Central nervous system imaging revealed a cerebral infarction. To our knowledge, the constellation of APS2, stroke and acute mental status change has not been previously reported. We review the literature with regard to the presentation of AI as well as the association between vasculitis and APS2. PMID:24259239

  5. The Status of the MARE Experiment with 187Re and 163Ho Isotopes

    NASA Astrophysics Data System (ADS)

    Ferri, E.; Bagliani, D.; Biasotti, M.; Ceruti, G.; Corsini, D.; Faverzani, M.; Gatti, F.; Giachero, A.; Gotti, C.; Kilbourne, C.; Kling, A.; Maino, M.; Manfrinetti, P.; Nucciotti, A.; Pessina, G.; Pizzigoni, G.; Gomes, M. Ribeiro; Sisti, M.

    Neutrino oscillation experiments have proved that neutrinos are massive particles but the assessment of their absolute mass scale is still an outstanding challenge in today particle physics and cosmology. The laboratory experiments dedicated to effective electron-neutrino mass determination are the ones based on the study of single beta decay or electron capture (EC) decay. Exploiting only on energy-momentum conservation, this kinematic measurement is the only one which permits to estimate neutrino masses without theoretical assumptions on neutrino nature and it is truly model-independent. To date the most competitive isotopes for a calorimetric measurement of the neutrino mass are 187Re and 163Ho. While the first decays beta, the latter decays via electron capture, and both have a Q-value around 2.5 keV. The measurement of 163Ho EC is an appealing alternative to the 187Re beta decay measurement because few nuclei are needed and it is a self-calibrating measurement. In this context the MARE project, based on rhenium thermal detectors has been born. We report here the status of MARE in Milan with Rhenium and the activity concerning the production of radioactive 163Ho isotope in the framework of MARE.

  6. Present status and future perspectives of ALPPS (associating liver partition and portal vein ligation for staged hepatectomy).

    PubMed

    Donati, Marcello; Basile, Francesco; Oldhafer, Karl J

    2015-01-01

    First International Consensus Meeting, Hamburg, Germany, 27-28 February 2015 More than 160 participants took part in the conference for 2 days. A total of 58 world renown experts on ALPPS (associating liver partition and portal vein ligation for staged hepatectomy) were invited from all over the world. The faculty was divided into many different subgroups that were in contact during the 2-3 months before the conference analyzing all the most important aspects of this technique and summarizing it in a common structured work to be presented during the congress, giving final recommendations in the form of bulleted point statements. The aim was to gain a solid basis of preliminary agreement on many controversial aspects of ALPPS. A poster area was also organized with 35 posters reporting mostly mono-institutional experiences on single aspects of the technique from all five continents. PMID:26260803

  7. Evaluation of EGFR mutation status in cytology specimens: an institutional experience.

    PubMed

    Aisner, D L; Deshpande, C; Baloch, Z; Watt, C D; Litzky, L A; Malhotra, B; Sepulveda, A R; Langer, C; Evans, T; Van Deerlin, V M

    2013-04-01

    Epidermal growth factor receptor (EGFR) mutation status has been shown to predict response to anti-EGFR tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC). In patients with advanced-stage NSCLC, evaluation of mutational status is increasingly requested on biopsy or fine-needle aspiration specimens, which often have limited material. There are limited data on the suitability of cytology cell blocks (CB) for EGFR mutation testing. In this study, we report our institutional experience with cytology cell block material for EGFR mutation testing. We retrospectively reviewed EGFR mutation analyses performed on 234 surgical (SP) and cytology (CB) from October 2007 to May 2010. One hundred ninety-two SP specimens and 42 CB specimens were evaluated for EGFR mutation. CB specimens were evaluated for overall specimen size based on aggregate cellularity in comparison to small biopsy specimens, and percent tumor. Of the 192 SP and 42 CB specimens, 31 (16.1%) and 11 (26.2%) were positive for EGFR mutation, respectively; there does not appear to be an association between mutation detection rate and the source of the specimen (P = 0.124). Limited DNA was obtained from 70.0% (29/42), including 81.8% (9/11) of those which were mutation positive. Additionally, 45.4% (5/11) of mutation positive specimens had extremely low DNA yields. Although 16.6% (7/42) of CB specimens had <10% tumor, all 11 mutation positive CB cases had >10% tumor. These data indicate that CB specimens provide an alternative source for molecular evaluation of NSCLC, and that tumor percentage may be more important than specimen size and/or DNA yield in determining the suitability of these specimens for testing.

  8. Status of the Jefferson Lab RSS Experiment (E01-006)

    SciTech Connect

    P.M. McKee

    2003-01-01

    Experiment E01-006 ran in Hall C of Jefferson Laboratory, Newport News, Virginia, for six weeks in early 2002. It featured a continuous beam of polarized electrons at 5.759 GeV hitting a polarized target of solid ammonia. Two types of ammonia, 15NH3 and 15ND3, were used so that proton and deuteron structure functions could be measured. Additionally, the polarization axis of the target was changed during the experiment to enable measurement of both longitudinal and transverse structure functions. Details and early analysis results will be presented.

  9. Experiences using Visualization Techniques to Present Requirements, Risks to Them, and Options for Risk Mitigation

    NASA Technical Reports Server (NTRS)

    Feather, Martin S.; Cornford, Steven L.; Kiper, James D.; Menzies, Tim

    2006-01-01

    For several years we have been employing a risk-based decision process to guide development and application of advanced technologies, and for research and technology portfolio planning. The process is supported by custom software, in which visualization plays an important role. During requirements gathering, visualization is used to help scrutinize the status (completeness, extent) of the information. During decision making based on the gathered information, visualization is used to help decisionmakers understand the space of options and their consequences. In this paper we summarize the visualization capabilities that we have employed, indicating when and how they have proven useful.

  10. Multigenerational links between mothers' experiences of autonomy in childhood and preschoolers' respiratory sinus arrhythmia: Variations by maltreatment status.

    PubMed

    Noll, Laura K; Clark, Caron A C; Skowron, Elizabeth A

    2015-11-01

    Despite burgeoning evidence linking early exposure to child maltreatment (CM) to deficits in self-regulation, the pathways to strong regulatory development in these children are not well understood, and significant heterogeneity is observed in their outcomes. Experiences of autonomy may play a key role in transmitting self-regulatory capacity across generations and help explain individual differences in maltreatment outcomes. In this study, we investigated multigenerational associations between Generation 1 (G1)-Generation 2 (G2) mothers' early experience of warmth and autonomy in relation to their own mothers and their Generation 3 (G3) children's autonomic physiological regulation in CM (n = 85) and non-CM (n = 128) families. We found that G2 mothers who recalled greater autonomy in their childhood relationship with their G1 mothers had preschool-age G3 children with higher respiratory sinus arrhythmia at baseline when alone while engaged in individual challenge tasks, during social exchanges with their mother in joint challenge tasks, and during the portions of the strange situation procedure when the mother was present. Although no clear mediators of this association emerged, multigenerational links among G1-G2 relations, maternal representations of her child, child behavior, and child respiratory sinus arrhythmia differed by maltreatment status, thus possibly representing important targets for future research and intervention. PMID:26535936

  11. Patients’ and caregivers’ experiences of the impact of Parkinson’s disease on health status

    PubMed Central

    Chiong-Rivero, Horacio; Ryan, Gery W; Flippen, Charles; Bordelon, Yvette; Szumski, Nicholas R; Zesiewicz, Theresa A; Vassar, Stefanie; Weidmer, Beverly; García, Rosa Elena; Bradley, Melissa; Vickrey, Barbara G

    2011-01-01

    Background: Parkinson’s disease (PD) is a neurodegenerative disease that significantly affects patients’ quality of life. The myriad complexities of the disease, including its nonmotor manifestations, are beginning to be more fully appreciated, particularly in regard to the emotional and social effects of PD. Considering that both motor and nonmotor manifestations of PD significantly influence the health outcomes and conditions of patients, and their health-related quality of life (HRQOL), we collected qualitative data from patients with PD, as well as caregivers of persons with PD having cognitive impairment, to assess their perceptions of the impact of PD on HRQOL. Methods: We conducted eight focus groups and five one-on-one interviews in English and in Spanish between March 2007 and February 2008. Three of the focus groups were conducted with a total of 15 caregivers; the remaining focus groups and all interviews were conducted with 48 PD patients. Study participants were asked about the challenges that PD patients may experience, particularly pertaining to physical functioning, the impact of PD on their emotional status, and social functioning. Results: Based on analysis of the transcripts, we identified seven overarching domains or themes that reflect patients’ perspectives on living with PD, ie, physical functioning, social and role functioning, emotional impact, fears and uncertainty about the future, stigma and other feelings about PD, coping mechanisms, and benefits of having PD. Conclusion: We underscore the salient aspects regarding the physical effects of PD along with its nonphysical ramifications, offering perspectives into the experience of PD and suggestions on how PD patients and their caregivers may cope with the disease. PMID:21691459

  12. Status of the NEXT experiment and future perspectives for HPXe-based DBD searches

    NASA Astrophysics Data System (ADS)

    Cadenas, Juan

    2014-09-01

    Neutrinos may be Majorana particles. If so, neutrinoless double beta decay processes could be observed by the next-generation bb0nu experiments. This talk will present one of the most promising ideas in the field, the use of a High Pressure Gas Xenon TPC (HPGXe) with electroluminescence gain and optical readout. A 100 kg incarnation of such a device, the NEXT-100 experiment, will start operations at the Canfranc Underground Lab in Spain in 2015. The technology can be extrapolated to 1 ton, and thus lead the exploration of the inverse hierarchy in Majorana landscape. Neutrinos may be Majorana particles. If so, neutrinoless double beta decay processes could be observed by the next-generation bb0nu experiments. This talk will present one of the most promising ideas in the field, the use of a High Pressure Gas Xenon TPC (HPGXe) with electroluminescence gain and optical readout. A 100 kg incarnation of such a device, the NEXT-100 experiment, will start operations at the Canfranc Underground Lab in Spain in 2015. The technology can be extrapolated to 1 ton, and thus lead the exploration of the inverse hierarchy in Majorana landscape. Thanks: Advanced Grant/ERC; CSIC and MINECO CONSOLIDER GREANT- CUP.

  13. Beta-decay of 31Cl: an indirect probe of the 30P(p,γ)31S reaction. Present status and future perspectives

    NASA Astrophysics Data System (ADS)

    Saastamoinen, Antti; Kankainen, Anu; Trache, Livius

    2016-08-01

    β-decay of 31Cl can be used as a selective tool for studying astrophysically relevant states in 31S. In this article we review the present status of the decay data. The implications for the 30P(p,γ)31S reaction rate at novae temperatures, and future experimental ideas are discussed.

  14. [A study on the relationship between women's health status and the experience of Sanhujori, the Korean traditional non-professional postpartal care].

    PubMed

    Eun, K Y

    1997-01-01

    This descriptive study sought to define the relationship between women's health status and the experience of Sanhujori. Korean traditional non-professional postpartal care after delivery and abortion. A convenience sample of 308 women in 7 provinces in Korea including Seoul were studied from December, 1994 to December, 1996 for two years. Mean age of respondents was 50.5 years and mean number of children was 3. The rate of abortion was 91.5% and mean frequency was 2.2 times per woman. 82% of respondents did not have Sanhujori after abortion. The period and subjective evaluation of experience of Sanhujori after delivery were decreased according to the increment of the number of childbirth. The health status implies both subjective health status women perceived and physical symptom distress women are experiencing presently. The respondents expressed the physical symptom distress as painful one. 56.7% of respondents perceived unhealthy, such as sick and 99.6% complained more than one symptom. The factors related to health status were the first and third experience of Sanhujori after delivery, such as the period and subjective evaluation whether she did Sanhujori well or not; whether or not of Sanhujori after abortion and menopause; the number of child; and age, at the level of 1% or 5% of significance statistically. The factors related to the rate of physical symptom distress were only two: the first experience of Sanhujori after delivery, especially the subjective evaluation and whether women did Sanhujori after abortion or not, at the level of 1% or 5% of significance statistically. In conclusion, this finding reconfirmed the possible relationship between women's health status and the experience of Sanhujori after delivery & abortion. It provides a challenge to the professional care givers to research further on the effects of Sanhujori on the health status, health recovery after abortion or delivery from the various aspects through the cross-sectional and

  15. Organization of Experience among Family Members in the Immediate Present: A Gestalt/Systems Integration.

    ERIC Educational Resources Information Center

    Kaplan, Marvin L.; Kaplan, Netta R.

    1982-01-01

    Outlines two formulations that generate conceptual perspectives of immediate phenomena: (1) the family system has a time-enduring stability; (2) the family system has an immediate and temporary organization. Integrates systems thinking and Gestalt Therapy while recognizing individual experience as embedded in a self-maintaining system of the…

  16. The Roles of Prior Experience and the Timing of Misinformation Presentation on Young Children's Event Memories

    ERIC Educational Resources Information Center

    Roberts, Kim P.; Powell, Martine B.

    2007-01-01

    The current study addressed how the timing of interviews affected children's memories of unique and repeated events. Five- to six-year-olds (N = 125) participated in activities 1 or 4 times and were misinformed either 3 or 21 days after the only or last event. Although single-experience children were subsequently less accurate in the 21- versus…

  17. Eutrophication status of the North Sea, Skagerrak, Kattegat and the Baltic Sea in present and future climates: A model study

    NASA Astrophysics Data System (ADS)

    Skogen, Morten D.; Eilola, Kari; Hansen, Jørgen L. S.; Meier, H. E. Markus; Molchanov, Mikhail S.; Ryabchenko, Vladimir A.

    2014-04-01

    A method to combine observations and an ensemble of ecological models has been used to assess eutrophication. Using downscaled forcing from two GCMs under the A1B emission scenario, an assessment of the eutrophication status was made for a control (1970-2000) and a future climate (2070-2100) period. By using validation results from a hindcast to compute individual weights between the models, an assessment of eutrophication is done using a set of threshold values. The final classification distinguishes between three categories: problem area, potential problem area, and non-problem area, in accordance with current management practice as suggested by the Oslo and Paris Commissions (OSPAR) and the Helsinki Commission (HELCOM). For the control run the assessment indicates that the Kattegat, the Danish Straits, the Gulf of Finland, the Gotland Basin as well as main parts of the Arkona Basin, the Bornholm Basin, and the Baltic proper may be classified as problem areas. The main part of the North Sea and also the Skagerrak are non-problem areas while the main parts of the Gulf of Bothnia, Gulf of Riga and the entire southeastern continental coast of the North Sea may be classified as potential problem areas. In the future climate scenarios most of the previous potential problem areas in the Baltic Sea have become problem areas, except for the Bothnian Bay where the situation remain fairly unchanged. In the North Sea there seems to be no obvious changes in eutrophication status in the projected future climate.

  18. The efficacy of topiramate in adult refractory status epilepticus: experience of a tertiary care center.

    PubMed

    Synowiec, Andrea S; Yandora, Kristin A; Yenugadhati, Vamsi; Valeriano, James P; Schramke, Carol J; Kelly, Kevin M

    2012-02-01

    Refractory status epilepticus (RSE) occurs in patients with SE when they fail to respond to traditional medical therapy. Because there are very few case reports of topiramate (TPM) treatment of RSE in adult patients, we examined our experience with TPM with regard to its safety and efficacy in seizure termination in RSE in an adult patient population. We report a retrospective review of 35 adult patients with RSE who were treated with TPM in addition to other antiepileptic drugs (AEDs) between 2003 and 2010. After failure of initial treatments of benzodiazepines and weight-based intravenous loading doses of standard AEDs, TPM tablets were crushed and administered via nasogastric tube. Data were collected on age, gender, history of epilepsy, etiology of RSE, daily dose of TPM, co-therapeutic agents, treatment response, and disposition. Following initiation of TPM use and discontinuation of continuous intravenous anesthetics with no additional AEDs administered, cumulative cessation of RSE in patients was 4/35 (11%) at one day, 10/35 (29%) at two days, and 14/35 (40%) at three days. However, when including all patients and comparing the two patient groups in which RSE was or was not terminated within three days of initiating TPM as the last or not last AED given, there was no significant difference. Time to TPM response was not associated with the type of seizures, etiology of SE, or whether there was a history of epilepsy. There were no documented side effects or complications of therapy with TPM. This study provides support for the use of TPM as an adjunctive agent in the treatment of RSE.

  19. The National Analysis Facility at DESY - status and use cases by the participating experiments

    NASA Astrophysics Data System (ADS)

    Aplin, S.; Ehrenfeld, W.; Haupt, A.; Kemp, Y.; Langenbruch, C.; Leffhalm, K.; Lucaci-Timoce, A.; Stadie, H.

    2011-12-01

    The German National Analysis Facility (NAF) was set up at DESY, starting end of 2007 in the context of the Helmholtz Alliance "Physics at the Terascale". The NAF complements the DESY and the German Grid resources, and hence offers users from the German HEP institutes the best possible environment for data analysis. In the first part, the key aspects and components of the NAF are briefly presented with an emphasis on recent improvements. In the second part, the use cases of the three participating LHC experiments, ATLAS, CMS and LHCb, will be presented. Differences and commonalities in the usage of the NAF will be shown. Special emphasis will be placed on the usage of PROOF, whose usage on the NAF has been pioneered by CMS. It is now adapted by ATLAS. The third part will concentrate on how the NAF was used for detector optimisation studies in the preparation of one of the ILC Lol's (ILD 2009), as well as how CALICE uses the NAF for the analysis of their data taken in several test beam experiments performed for detector R & D. Finally, future developments of the NAF are presented.

  20. Fish status survey of Nordic lakes: effects of acidification, eutrophication and stocking activity on present fish species composition.

    PubMed

    Tammi, Jouni; Appelberg, Magnus; Beier, Ulrika; Hesthagen, Trygve; Lappalainen, Antti; Rask, Martti

    2003-03-01

    The status of fish populations in 3821 lakes in Norway, Sweden and Finland was assessed in 1995-1997. The survey lakes were chosen by stratified random sampling from all (126 482) Fennoscandian lakes > or = 0.04 km2. The water chemistry of the lakes was analyzed and information on fish status was obtained by a postal inquiry. Fish population losses were most frequent in the most highly acidified region of southern Norway and least common in eastern Fennoscandia. According to the inquiry results, the number of lost stocks of brown trout (Salmo trutta), roach (Rutilus rutilus), Arctic char (Salvelinus alpinus) and perch (Perca fluviatilis) was estimated to exceed 10000. The number of stocks of these species potentially affected by the low alkalinity of lake water was estimated to exceed 11000. About 3300 lakes showed high total phosphorus (> 25 microg L(-1)) and cyprinid dominance in eastern Fennoscandia, notably southwestern Finland. This survey did not reveal any extinction of fish species due to eutrophication. One-third of the lakes had been artificially stocked with at least one new species, most often brown trout, whitefish (Coregonus lavaretus s.l.), Arctic char, rainbow trout (Oncorhynchus mykiss), pike-perch (Stizostedion lucioperca), grayling (Thymallus thymallus), pike (Esox lucius), bream (Abramis brama), tench (Tinca tinca) and European minnow (Phoxinus phoxinus). The number of artificially manipulated stocks of these species in Fennoscandian lakes was estimated to exceed 52000. Hence, the number of fish species occurring in Nordic lakes has recently been changed more by stockings than by losses of fish species through environmental changes such as acidification.

  1. Chikungunya Fever Presenting as a Systemic Disease with Fever. Arthritis and Rash: Our Experience in Israel.

    PubMed

    Tanay, Amir

    2016-01-01

    Chikungunya fever (CHIK-F) has been increasingly documented among Western travelers returning from areas with chikungunya virus transmission, which are also popular tourist sites. We present three Israeli travelers who developed fever, maculopapular rash and long-standing arthralgias while visiting northern Indian states not known to be involved in the chikungunya fever epidemic. We also present an epidemiological review of the chikungunya epidemic over the past decades. Rare systemic manifestations of this disorder, like catastrophic antiphospholipid syndrome (CAPS) and adult-onset Still's syndrome, are discussed. The present era of international travel poses a new diagnostic and epidemiologic challenge that demands increased awareness to the possibility of an exotic tropical infectious disease.

  2. The Online Histogram Presenter for the ATLAS experiment: A modular system for histogram visualization

    NASA Astrophysics Data System (ADS)

    Dotti, Andrea; Adragna, Paolo; Vitillo, Roberto A.

    2010-04-01

    The Online Histogram Presenter (OHP) is the ATLAS tool to display histograms produced by the online monitoring system. In spite of the name, the Online Histogram Presenter is much more than just a histogram display. To cope with the large amount of data, the application has been designed to minimise the network traffic; sophisticated caching, hashing and filtering algorithms reduce memory and CPU usage. The system uses Qt and ROOT for histogram visualisation and manipulation. In addition, histogram visualisation can be extensively customised through configuration files. Finally, its very modular architecture features a lightweight plug-in system, allowing extensions to accommodate specific user needs. After an architectural overview of the application, the paper is going to present in detail the solutions adopted to increase the performance and a description of the plug-in system.

  3. Group B Streptococcus vaccine development: present status and future considerations, with emphasis on perspectives for low and middle income countries

    PubMed Central

    Kobayashi, Miwako; Vekemans, Johan; Baker, Carol J.; Ratner, Adam J.; Le Doare, Kirsty; Schrag, Stephanie J.

    2016-01-01

    Globally, group B Streptococcus (GBS) remains the leading cause of sepsis and meningitis in young infants, with its greatest burden in the first 90 days of life. Intrapartum antibiotic prophylaxis (IAP) for women at risk of transmitting GBS to their newborns has been effective in reducing, but not eliminating, the young infant GBS disease burden in many high income countries. However, identification of women at risk and administration of IAP is very difficult in many low and middle income country (LMIC) settings, and is not possible for home deliveries. Immunization of pregnant women with a GBS vaccine represents an alternate pathway to protecting newborns from GBS disease, through the transplacental antibody transfer to the fetus in utero. This approach to prevent GBS disease in young infants is currently under development, and is approaching late stage clinical evaluation. This manuscript includes a review of the natural history of the disease, global disease burden estimates, diagnosis and existing control options in different settings, the biological rationale for a vaccine including previous supportive studies, analysis of current candidates in development, possible correlates of protection and current status of immunogenicity assays. Future potential vaccine development pathways to licensure and use in LMICs, trial design and implementation options are discussed, with the objective to provide a basis for reflection, rather than recommendations. PMID:27803803

  4. Poster Presentations: Turning a Lab of the Week into a Culminating Experience

    ERIC Educational Resources Information Center

    Logan, Jennifer L.; Quin~ones, Rosalynn; Sunderland, Deborah P.

    2015-01-01

    An assignment incorporating posters into a second-year analytical chemistry lab is described. Students work in groups and are assigned one of the application-themed weekly laboratories as a topic. Course data acquired for these weekly laboratories are compiled into spreadsheets that the poster group then analyzes to present in an on-campus poster…

  5. On the Presentation of Wave Phenomena of Electrons with the Young-Feynman Experiment

    ERIC Educational Resources Information Center

    Matteucci, Giorgio

    2011-01-01

    The Young-Feynman two-hole interferometer is widely used to present electron wave-particle duality and, in particular, the buildup of interference fringes with single electrons. The teaching approach consists of two steps: (i) electrons come through only one hole but diffraction effects are disregarded and (ii) electrons come through both holes…

  6. From School Libraries to School Media Centres: Experiences, the Present Situation and Possible Improvement.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific and Cultural Organization, Paris (France). Div. of Educational Sciences, Contents & Methods of Educ.

    This report presents case studies of the role of school libraries and their transformation into school media centers in elementary and secondary schools in Serbia, Croatia, and Hungary. It is noted that the school media center is not conceived of as a simple mechanism for storing books and audiovisual aids, but as an active center for…

  7. Parity Violation in Chiral Molecules: Current Status of Theory and Spectroscopic Experiment

    NASA Astrophysics Data System (ADS)

    Quack, Martin; Seyfang, Georg

    2013-06-01

    In the ordinary quantum chemistry based on the electromagnetic interaction the ground state energies of enantiomers of chiral molecules are exactly the same by symmetry. Parity violation in electroweak interactions leads to a small ``parity violating'' energy difference Δ_{pv}E between the ground states of enantiomers corresponding to a heat of reaction for stereomutation Δ_{{R}} {H}_0 ^ominus ˜eq 10^{-11} J mol^{-1}, (typically, or about 100 aeV corresponding to about 10^{-12} cm^{-1}). After our finding (in 1995) that a revised theory leads to about a factor of 10 to 100 higher values than previously calculated in older theoretical work prior to 1995, the theoretical results from many groups have now essentially converged to the new values (see reviews). However, experimental results for Δ_{pv}E are still missing. We shall discuss the status of ongoing experiments in the Zürich group to detect this exceedingly small effect by spectroscopy following a scheme proposed in 1986 and shall discuss also the comparison with other efforts. M. Quack, Frontiers in Spectroscopy, in Faraday Discussions, Vol. 150, pp. 533-565, 2011. M. Quack, Fundamental Symmetries and Symmetry Violations from High Resolution Spectroscopy, in Handbook of High Resolution Spectroscopy, Vol. 1, Chapt. 18, pp. 659-722 (Eds.: M. Quack, F. Merkt), Wiley, Chichester, New York, 2011, ISBN 978-0-470-06653-9. M. Quack, J. Stohner, M. Willeke, High-resolution spectroscopic studies and theory of parity violation in chiral molecules, Annu. Rev. Phys. Chem., 2008, 59, 741-769. M. Quack, On the measurement of the parity violating energy difference between enantiomers, Chem. Phys. Lett., 1986, 132, 147-153. P. Dietiker, M. Quack, A. Schneider, G. Seyfang, F. Ünlü, IR-laser induced population transfer from highly populated rotational levels of NH_3 in a molecular beam, in Proceedings of the 18th Symposium on Atomic, Cluster and Surface Physics 2012 (SASP 2012), Alpe d`Huez, France, 22 to 27 January 2012

  8. Can a stroke present with flexor spasms? A highly rare experience.

    PubMed

    Malik, Yasir Mehmood; Almadani, Abubaker Abdulrahman; Dar, Jaeed Ahmed

    2014-01-01

    Involuntary movement disorders are not a common presentation of basal ganglia ischemia which may be induced by cerebral hemodynamic insufficiency. In secondary causes of movements disorders cerebrovascular diseases represent up to 22% and involuntary movements develop after 1-4% of strokes. We describe a case of a middle-aged woman who presented with intermittent involuntary tonic spasms or seizure-like episodes followed by weakness due to contralateral putaminal infarction. Initially thought to have Todd's paralysis she was not thrombolysed, but later she developed dense hemiplegia. Flexor spasms are generally thought to occur in lesions of the spinal cord but they can also occur in cerebral lesion, may be because of disinhibition of the spinal cord. Certain other theories also have been narrated, but this field still needs to be worked upon.

  9. The International Space Station: Operations and Assembly - Learning From Experiences - Past, Present, and Future

    NASA Technical Reports Server (NTRS)

    Fuller, Sean; Dillon, William F.

    2006-01-01

    As the Space Shuttle continues flight, construction and assembly of the International Space Station (ISS) carries on as the United States and our International Partners resume the building, and continue to carry on the daily operations, of this impressive and historical Earth-orbiting research facility. In his January 14, 2004, speech announcing a new vision for America s space program, President Bush ratified the United States commitment to completing construction of the ISS by 2010. Since the launch and joining of the first two elements in 1998, the ISS and the partnership have experienced and overcome many challenges to assembly and operations, along with accomplishing many impressive achievements and historical firsts. These experiences and achievements over time have shaped our strategy, planning, and expectations. The continual operation and assembly of ISS leads to new knowledge about the design, development and operation of systems and hardware that will be utilized in the development of new deep-space vehicles needed to fulfill the Vision for Exploration and to generate the data and information that will enable our programs to return to the Moon and continue on to Mars. This paper will provide an overview of the complexity of the ISS Program, including a historical review of the major assembly events and operational milestones of the program, along with the upcoming assembly plans and scheduled missions of the space shuttle flights and ISS Assembly sequence.

  10. Present experience of NRI REZ with preparation of spent nuclear fuel shipment to Russian Federation

    SciTech Connect

    Svitak, F.; Broz, V.; Hrehor, M.; Marek, M.; Novosad, P.; Podlaha, J.; Rychecky, J.

    2008-07-15

    The Nuclear Research Institute Rez plc (NRI) jointed the Russian Research Reactor Fuel Return (RRRFR) programme under the US-Russian Global Threat Reduction Initiative (GTRI) initiative and started the preparation of the spent nuclear fuel (SNF) shipment from the LVR-15 research reactor back to the Russian Federation (RF). The transport of 16 SKODA VPVR/M casks with EK-10, IRT-2M 80 %, and IRT-2M 36% fuel types is planned for the autumn of 2007. The paper describes the experience gained so far during the preparatory works for the SNF shipment (facility equipment modification, cask licenses) and the actual preparation of the SNF for transport, in particular its checking, repacking in a hot cell, loading into the VPVR/M casks, drying, manipulation, completion of the transport documentation, etc., including its transport to the SNF storage facility at the NRI before it is shipped to the RF. The paper also briefly describes a regulatory framework for these activities with a focus on legislative and methodological aspects of the return of vitrified waste back to the Czech Republic. (author)

  11. Dosimetry at the Los Alamos Critical Experiments Facility: Past, present, and future

    SciTech Connect

    Malenfant, R.E.

    1993-10-01

    Although the primary reason for the existence of the Los Alamos Critical Experiments Facility is to provide basic data on the physics of systems of fissile material, the physical arrangements and ability to provide sources of radiation have led to applications for all types of radiation dosimetry. In the broad definition of radiation phenomena, the facility has provided sources to evaluate biological effects, radiation shielding and transport, and measurements of basic parameters such as the evaluation of delayed neutron parameters. Within the last 15 years, many of the radiation measurements have been directed to calibration and intercomparison of dosimetry related to nuclear criticality safety. Future plans include (1) the new applications of Godiva IV, a bare-metal pulse assembly, for dosimetry (including an evaluation of neutron and gamma-ray room return); (2) a proposal to relocate the Health Physics Research Reactor from the Oak Ridge National Laboratory to Los Alamos, which will provide the opportunity to continue the application of a primary benchmark source to radiation dosimetry; and (3) a proposal to employ SHEBA, a low-enrichment solution assembly, for accident dosimetry and evaluation.

  12. Does Posting Facebook Status Updates Increase or Decrease Loneliness? An Online Social Networking Experiment.

    PubMed

    Deters, Fenne Große; Mehl, Matthias R

    2013-09-01

    Online social networking is a pervasive but empirically understudied phenomenon. Strong public opinions on its consequences exist but are backed up by little empirical evidence and almost no causally-conclusive, experimental research. The current study tested the psychological effects of posting status updates on Facebook using an experimental design. For one week, participants in the experimental condition were asked to post more than they usually do, whereas participants in the control condition received no instructions. Participants added a lab "Research Profile" as a Facebook friend allowing for the objective documentation of protocol compliance, participants' status updates, and friends' responses. Results revealed (1) that the experimentally-induced increase in status updating activity reduced loneliness, (2) that the decrease in loneliness was due to participants feeling more connected to their friends on a daily basis and (3) that the effect of posting on loneliness was independent of direct social feedback (i.e. responses) by friends. PMID:24224070

  13. Does Posting Facebook Status Updates Increase or Decrease Loneliness? An Online Social Networking Experiment.

    PubMed

    Deters, Fenne Große; Mehl, Matthias R

    2013-09-01

    Online social networking is a pervasive but empirically understudied phenomenon. Strong public opinions on its consequences exist but are backed up by little empirical evidence and almost no causally-conclusive, experimental research. The current study tested the psychological effects of posting status updates on Facebook using an experimental design. For one week, participants in the experimental condition were asked to post more than they usually do, whereas participants in the control condition received no instructions. Participants added a lab "Research Profile" as a Facebook friend allowing for the objective documentation of protocol compliance, participants' status updates, and friends' responses. Results revealed (1) that the experimentally-induced increase in status updating activity reduced loneliness, (2) that the decrease in loneliness was due to participants feeling more connected to their friends on a daily basis and (3) that the effect of posting on loneliness was independent of direct social feedback (i.e. responses) by friends.

  14. Does Posting Facebook Status Updates Increase or Decrease Loneliness? An Online Social Networking Experiment

    PubMed Central

    Deters, Fenne große; Mehl, Matthias R.

    2013-01-01

    Online social networking is a pervasive but empirically understudied phenomenon. Strong public opinions on its consequences exist but are backed up by little empirical evidence and almost no causally-conclusive, experimental research. The current study tested the psychological effects of posting status updates on Facebook using an experimental design. For one week, participants in the experimental condition were asked to post more than they usually do, whereas participants in the control condition received no instructions. Participants added a lab “Research Profile” as a Facebook friend allowing for the objective documentation of protocol compliance, participants’ status updates, and friends’ responses. Results revealed (1) that the experimentally-induced increase in status updating activity reduced loneliness, (2) that the decrease in loneliness was due to participants feeling more connected to their friends on a daily basis and (3) that the effect of posting on loneliness was independent of direct social feedback (i.e. responses) by friends. PMID:24224070

  15. Extracorporeal carbon dioxide removal for refractory status asthmaticus: experience in distinct exacerbation phenotypes.

    PubMed

    Brenner, K; Abrams, D C; Agerstrand, C L; Brodie, D

    2014-01-01

    Extracorporeal carbon dioxide removal (ECCO2R) may be indicated for refractory status asthmaticus when severe dynamic hyperinflation or life-threatening respiratory acidosis persists despite optimal medical and ventilator management. Most prior reports describe the application of ECCO2R to rapid-onset asthma exacerbation, requiring a short duration of extracorporeal support. We report two patients with refractory status asthmaticus managed with ECCO2R, emphasizing the use of modern extracorporeal technology, cannulation technique and management protocols, which may improve the risk-to-benefit profile of this strategy. This report highlights the challenges in managing patients with distinct asthma exacerbation phenotypes. The potential need for prolonged device support may alter provider expectations and offers a new perspective of the role of ECCO2R for status asthmaticus.

  16. Goals and Status of MICE, the International Muon Ionization Cooling Experiment

    NASA Astrophysics Data System (ADS)

    Snopok, Pavel; Muon Ionization Cooling Experiment Collaboration

    2011-04-01

    Muon ionization cooling provides the only practical solution to preparing the low-emittance muon beams suitable for a neutrino factory or a muon collider. The Muon Ionization Cooling Experiment (MICE) thus represents a strategic R&D project for neutrino physics. MICE is under development at the Rutherford Appleton Laboratory (UK). It comprises a dedicated muon beam line able to generate a range of input emittance and momentum values, with time-of-flight and Cherenkov detectors to ensure a pure muon beam. A first measurement of emittance will be performed in the upstream magnetic spectrometer with a scintillating-fiber tracker. A cooling cell will then follow, alternating energy loss in liquid-hydrogen absorbers and RF acceleration. A second spectrometer, identical to the first, and a second muon identification system provide a measurement of the outgoing emittance. In the 2010 run, completed in August, the beam and most detectors were fully commissioned. Results from this run will be presented. The plan for measurements of emittance and emittance reduction (cooling) that will follow in 2011 and beyond will also be reported. On behalf of the Muon Ionization Cooling Experiment collaboration.

  17. The status of the study of solar CNO neutrinos in the Borexino experiment

    SciTech Connect

    Lukyanchenko, G. A.; Collaboration: Borexino Collaboration

    2015-12-15

    Although less than 1% of solar energy is generated in the CNO cycle, it plays a critical role in astrophysics, since this cycle is the primary source of energy in certain more massive stars and at later stages of evolution of solar-type stars. Electron neutrinos are produced in the CNO cycle reactions. These neutrinos may be detected by terrestrial neutrino detectors. Various solar models with different abundances of elements heavier than helium predict different CNO neutrino fluxes. A direct measurement of the CNO neutrino flux could help distinguish between these models and solve several other astrophysical problems. No CNO neutrinos have been detected directly thus far, and the best upper limit on their flux was set in the Borexino experiment. The work on reducing the background in the region of energies of CNO neutrinos (up to 1.74 MeV) and developing novel data analysis methods is presently under way. These efforts may help detect the CNO neutrino flux in the Borexino experiment at the level predicted by solar models.

  18. Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience

    PubMed Central

    AlZunaitan, Mohammed; Al Ghobain, Mohammed; Al Muaikeel, Mohamed; Al Olayan, Ashwaq; Azzumeea, Fahad; AlAlwan, Abduljaleel; AlGhamdi, Hamdan

    2016-01-01

    Objective. To investigate the risk factors, clinical characteristics, treatment modalities, and outcomes in Saudi patients with HCC and propose points for early detection of the disease. Methods. Patients were stratified according to underlying risk factors for the development of HCC. Barcelona Clinic Liver Cancer (BCLC) was used for cancer staging. Treatment was classified into surgical resection/liver transplantation; locoregional ablation therapy; transarterial embolization; systemic chemotherapy; and best supportive care. Results. A total of 235 patients were included. Males had higher tumor size and incidence of portal vein thrombosis. Viral hepatitis was a risk factor in 75.7%. The most common BCLC stages were B (34.5%) and A (33.6%), and the most common radiological presentation was a single nodule of less than 5 cm. Metastases were present in 13.2%. Overall, 77 patients (32.8%) underwent a potentially curative treatment as the initial therapy. The most commonly utilized treatment modality was chemoembolization with 113 sessions in 71 patients. The overall median survival was 15.97 ± 27.18 months. Conclusion. HCC in Saudi Arabia is associated with high prevalence of HCV. Potentially curative therapies were underutilized in our patients. Cancer stage BCLC-B was the most frequent (34.5%) followed by BCLC-A (33.6%). The overall median survival was shorter than other studies. PMID:27525001

  19. EDELWEISS-III experiment: Status and first low WIMP mass results

    NASA Astrophysics Data System (ADS)

    Scorza, Silvia; EDELWEISS Collaboration

    2016-05-01

    The EDELWEISS-III collaboration is operating an experiment for the direct detection of Weakly Interacting Massive Particle (WIMPs) dark matter in the low radioactivity environment of the Modane Underground Laboratory. It consists of 24 advanced high-purity germanium detectors operating at 18 mK in a dilution refrigerator in order to identify rare nuclear recoils induced by elastic scattering of WIMPs from our Galactic halo. The current EDELWEISS-III program, including improvements of the background, data-acquisition and the current installation will be detailed. Sources of background along with the rejection techniques will be discussed. Detector performances and a first low WIMP mass (Boosted Decision Tree) BDT- based analysis of data acquired in a long-term campaign will be presented as well.

  20. Experience of Varied Presentation of Chronic Progressive Disseminated Histoplasmosis in Immunocompetent Patients: A Diagnostic Conundrum

    PubMed Central

    Ghosh, Roumi; Mishra, Pranshu; Sen, Sumit; Maiti, Prasanta Kumar; Chatterjee, Govinda

    2016-01-01

    We report two cases of chronic progressive disseminated histoplasmosis with unusual and rare clinical picture in a patient with no underlying risk factor. One 50-year-old male, presented with hoarseness of voice, chronic cough, with a history of nonresponding anti-tubercular therapy, revealed mucocutaneous lesions on examination. Fungating vocal cord lesions were visualized on bronchoscopy, raised suspicion of carcinoma. The second case, a 22-year-old female, referred to hospital with suspected vasculitis, with complaints of “off and on” fever with decreased oral intake, arthralgia, who later developed generalized nodular skin eruptions. On investigation, human immunodeficiency virus test was found to be negative in both the cases. Histopathological findings of skin biopsy, adrenal and bone marrow aspirates raised suspicion, whereas fungal cultures confirmed Histoplasma infection. Although diagnosis was delayed, but both of them were successfully treated with amphotericin B.

  1. Experience of Varied Presentation of Chronic Progressive Disseminated Histoplasmosis in Immunocompetent Patients: A Diagnostic Conundrum

    PubMed Central

    Ghosh, Roumi; Mishra, Pranshu; Sen, Sumit; Maiti, Prasanta Kumar; Chatterjee, Govinda

    2016-01-01

    We report two cases of chronic progressive disseminated histoplasmosis with unusual and rare clinical picture in a patient with no underlying risk factor. One 50-year-old male, presented with hoarseness of voice, chronic cough, with a history of nonresponding anti-tubercular therapy, revealed mucocutaneous lesions on examination. Fungating vocal cord lesions were visualized on bronchoscopy, raised suspicion of carcinoma. The second case, a 22-year-old female, referred to hospital with suspected vasculitis, with complaints of “off and on” fever with decreased oral intake, arthralgia, who later developed generalized nodular skin eruptions. On investigation, human immunodeficiency virus test was found to be negative in both the cases. Histopathological findings of skin biopsy, adrenal and bone marrow aspirates raised suspicion, whereas fungal cultures confirmed Histoplasma infection. Although diagnosis was delayed, but both of them were successfully treated with amphotericin B. PMID:27688460

  2. Experience in presenting short courses in waste management technologies for secondary science and mathematics teachers

    SciTech Connect

    Toth, W.J.; Smith, T.H.; Garcia, M.M.; Ferguson, J.E.

    1991-01-01

    The Department of Energy (DOE) and its Idaho National Engineering Laboratory (INEL) are developing educational programs that will help avert projected shortages in scientific and engineering manpower. One approach to this end is to help teachers become better prepared to teach topics that enthuse more students. INEL developed and offered a Short Course in Waste Management Technologies for Secondary Science and Mathematics Teachers. Short Course has two purposes: (1) to provide secondary-level science and mathematics teachers with training and information that will be useful to them in the classroom, and (2) to provide information on a topic of widespread interest in today's society, i.e., the management of hazardous and radioactive wastes and the restoration and preservation of the environment. This paper describes the development of the Short Course and summarizes some of the lessons learned in the preparation and presentation of such courses. 2 refs., 2 tabs.

  3. Experience of Varied Presentation of Chronic Progressive Disseminated Histoplasmosis in Immunocompetent Patients: A Diagnostic Conundrum.

    PubMed

    Ghosh, Roumi; Mishra, Pranshu; Sen, Sumit; Maiti, Prasanta Kumar; Chatterjee, Govinda

    2016-01-01

    We report two cases of chronic progressive disseminated histoplasmosis with unusual and rare clinical picture in a patient with no underlying risk factor. One 50-year-old male, presented with hoarseness of voice, chronic cough, with a history of nonresponding anti-tubercular therapy, revealed mucocutaneous lesions on examination. Fungating vocal cord lesions were visualized on bronchoscopy, raised suspicion of carcinoma. The second case, a 22-year-old female, referred to hospital with suspected vasculitis, with complaints of "off and on" fever with decreased oral intake, arthralgia, who later developed generalized nodular skin eruptions. On investigation, human immunodeficiency virus test was found to be negative in both the cases. Histopathological findings of skin biopsy, adrenal and bone marrow aspirates raised suspicion, whereas fungal cultures confirmed Histoplasma infection. Although diagnosis was delayed, but both of them were successfully treated with amphotericin B. PMID:27688460

  4. The past, present, and future of molecular gels. What is the status of the field, and where is it going?

    PubMed

    Weiss, Richard G

    2014-05-28

    A Perspective is presented on the history and current understanding of molecular gels and the factors that must be considered to characterize them. The abilities of the most important structural, dynamic, and rheological tools available currently to provide the information necessary to follow the formation of a molecular gel from its initial sol phase and then to define it at different distance and time scales are discussed. Approaches to determining a priori when a molecule will gelate a selected liquid, as well as possible methodologies for overcoming current limitations in understanding molecular gels, are presented. Finally, some of the many potential and realized applications for these materials are enumerated.

  5. The Hyper-K experiment: Present and R&D for the next decade

    NASA Astrophysics Data System (ADS)

    Hadley, D. R.

    2016-07-01

    Hyper Kamiokande (Hyper-K), a proposed one-megaton water Cherenkov detector is the logical continuation of the highly successful program of neutrino physics and proton decay using the water Cherenkov technique. In its baseline design, the Hyper-K detector consists of two cylindrical tanks lying side-by-side, the outer dimensions of each tank being 48 m×54 m×250 m. The inner detector region will be instrumented with 99,000 20 in. photo-sensors. Hyper-K will offer a broad program of physics and astrophysics including precise measurements of the lepton mixing matrix and leptonic CP asymmetry with accelerator and atmospheric neutrinos and searches for nucleon decay. An international collaboration has been intensively working on the R&D of key components such as optimization of cavern and tank construction, development of high performance photosensor, calibration, readout and trigger systems, J-PARC neutrino beam improvement, and development of simulation and reconstruction software. In addition, new near detectors are being designed that employ novel techniques to maximise the Hyper-K beam physics potential. An overview of the R&D for Hyper-K and its near detectors is presented.

  6. Voltage control of nanoscale magnetoelastic elements: theory and experiments (Presentation Recording)

    NASA Astrophysics Data System (ADS)

    Carman, Gregory P.

    2015-09-01

    Electromagnetic devices rely on electrical currents to generate magnetic fields. While extremely useful this approach has limitations in the small-scale. To overcome the scaling problem, researchers have tried to use electric fields to manipulate a magnetic material's intrinsic magnetization (i.e. multiferroic). The strain mediated class of multiferroics offers up to 70% of energy transduction using available piezoelectric and magnetoelastic materials. While strain mediated multiferroic is promising, few studies exist on modeling/testing of nanoscale magnetic structures. This talk presents motivation, analytical models, and experimental data on electrical control of nanoscale single magnetic domain structures. This research is conducted in a NSF Engineering Research Center entitled Translational Applications for Nanoscale Multiferroics TANMS. The models combine micromagnetics (Landau-Lifshitz-Gilbert) with elastodynamics using the electrostatic approximation producing eight fully coupled nonlinear partial differential equations. Qualitative and quantitative verification is achieved with direct comparison to experimental data. The modeling effort guides fabrication and testing on three elements, i.e. nanoscale rings (onion states), ellipses (single domain reorientation), and superparamagnetic elements. Experimental results demonstrate electrical and deterministic control of the magnetic states in the 5-500 nm structures as measured with Photoemission Electron Microscopy PEEM, Magnetic Force Microscopy MFM, or Lorentz Transmission Electron Microscopy TEM. These data strongly suggests efficient control of nanoscale magnetic spin states is possible with voltage.

  7. The Iranian Health Insurance System; Past Experiences, Present Challenges And Future Strategies

    PubMed Central

    Davari, M; Haycox, A; Walley, T

    2012-01-01

    Background: The Iranian healthcare system is primarily an insurance based system. This structure has an important influence on the efficiency and equity of the provision of healthcare in Iran. This paper reviews the history of the Iranian healthcare system and the impact of the Iranian health insurance system on healthcare performance based on the results of interviews with key opinion leaders and empirical evidence. Methods: This review uses mixed methods: a systematic literature review of electronic databases supplemented by hand searching of books and journals including Government publications and other grey literature. The issues identified were explored through a series of semi-structured interviews with key informants from within the Iranian healthcare system. The interviews were recorded transcribed, coded, classified, and analysed thematically. Empirical evidence was also sought to support or contradict the views expressed in the interviews. Results: Sixteen interviews with key informants were conducted and presented anonymously. The interviewees raised many issues which were summarised into five main issues: increasing health expenditures, lack of systematic health technology assessment, very limited financial resources, challenging management and regulation, and uncovered population. Conclusion: A wide range of issues have affected the efficiency, quality and equity of the services provided by the Iranian healthcare system. The initial and most important step toward improving the efficiency, equity and quality of the health insurance system is to focus on evidence-based policy making to generate feasible, reasonable and comprehensive reforms. PMID:23193499

  8. The Benefits of High School Experiences on Growth in Occupational Status in U.S.

    ERIC Educational Resources Information Center

    Kim, Kyung-Nyun; Passmore, David L.

    2016-01-01

    In this study, we investigated high school graduates' school-to-work transition by considering their post-school occupational skill levels. Using an ordinal growth model analysis, occupational status increased in an arch-shaped curve as the number of years after high school graduation also increased. This growth trajectory was further related to…

  9. Report on the Oak Ridge sewage sludge land-farming experience. Part 1. Data presentation

    SciTech Connect

    Oakes, T.W.; Braunstein, H.M.; Daniels, K.L.; Ohnesorge, W.F.; Kitchings, J.T.; Alexander, W.A.

    1984-08-01

    Disposal of sludge from the City of Oak Ridge's sewage treatment facility on a 65-acre site on the Department of Energy's Oak Ridge Reservation was initiated in November 1983. On March 22, 1984, DOE and the City determined that the sludge contained radioactive materials. Application of sludge on the Reservation was suspended on March 25 and a comprehensive survey and sampling plan was instituted to radiologically characterize the disposal site. By April 1, a radiation walkover survey had been completed on the site and samples of air, water, and soil had been collected to be analyzed for the presence of radionuclides. The mean air dose rate, one meter above the ground surface, was found to be 13 ..mu..R/h with a range from about 8 ..mu..R/h, which is the usual background level in the area, to 21 ..mu..R/h. Concentrations of Cs-137 and Co-60, the principle contaminants in the soil, were essentially below the analytical detection limits in the air and water. About 350 soil samples were collected by extracting cores to a depth of 12 to 15 inches according to a systematic random sampling design. Each core was separated into three sections; the top 3 inches, a middle section, and the bottom 3 inches to represent layers on the site. The majority of the radioactivity was determined to be in the upper 3 inches of soil. A statistical treatment of the analytical results provided an estimate of the total activity at the site, the vertical distribution of the gamma activity, and the areal distribution of the primary radionuclides. A total of 170 mCi of activity was estimated as present in the top 3-inch layer of the 65-acre site, 69% of which was contributed by Co-60 and Cs-137, 23% by U-234 and Sr-90, and 8% by other minor radionuclides. 4 references, 12 figures, 43 tables.

  10. Present status of very high energy gamma ray astronomy and plans for an imaging gamma ray telescope in India

    NASA Astrophysics Data System (ADS)

    Bhat, C. L.

    1993-09-01

    The unequivocal detection of the Crab Nebula as the first-ever standard candle in the very high energy (VHE) bracket, made possible by the recently-developed Cerenkov Imaging Technique, marks a water-shed in the 20 year-old history of the TeV gamma-ray astronomy. It gives hope that, as with the Crab today, future detections in the field, too, will be on a firm statistical footing and the attendant investigations, more comprehensive in their content and range. The present mood in the field is one of cautious optimism. This paper gives an overview of the contemporary observational scene in the ground-based gamma-ray astronomy. It closes with an introduction to TACTIC, the first Indian Imaging gamma-ray telescope, presently under-development.

  11. [The program of Founding Research Centers for Emerging and Reemerging Infectious Diseases: the present status and future prospects].

    PubMed

    Okamoto, Yoshiko; Nagai, Yoshiyuki

    2007-12-01

    The program of Founding Research Centers for Emerging and Reemerging Infectious Diseases was commenced in 2005 with an outline for Japanese universities and research institutions to establish bilateral collaboration research bases in countries where emerging and reemerging infections are breaking out or will likely break out. So far, six universities and two institutions are participating in the program and ten collaboration bases have been established in six countries (five in Asia and one in Africa). Each research base aims to contribute to the security and safety of the partner and own countries by facilitating better understanding of infectious diseases, technology innovation in diagnosis, therapy and prevention, and human resources development. The experiences of the Reseau International des Instituts Pasteur (RIIP), France, and the Wellcome Trust Southeast Asian Tropical Medicine Research Units (Oxford Network), United Kingdom, which appear to share similar missions, suggest that infectious diseases research that is based on overseas research bases can produce first-time results through the building of long-term mutual trust with the counterparts. By referring to these networks as models, Japan's program should be implemented over the long run but not be based on a short-time perspective. Thus, secure funding is a major issue. PMID:18357759

  12. Fine-needle aspiration cytology: its origin, development, and present status with special reference to a developing country, India.

    PubMed

    Das, Dilip K

    2003-06-01

    Fine-needle aspiration cytology (FNAC) was performed on a large scale at Memorial Hospital, New York, during the 1930s, but during the ensuing years, it did not gain much encouragement in United States. The technique had a resurgence in Scandinavia during the 1950s and 1960s, where it flourished before spreading to other parts of the world. It had also a revival in the United States, which contributed enormously to this tool in each and every aspect. The status of FNA during 1966-2002 was assessed through review of MEDLINE search data on FNA and its correlation with World Bank website data on classification of countries. A total of 849 journals published 5,609 articles on FNA over a period of 37 years. Both the number of publishing journals and the number of published articles on FNA were low during the 1960s (3.5 +/- 0.58 and 4.0 +/- 0.82, respectively) and 1970s (20.3 +/- 14.72 and 25.0 +/- 20.54, respectively), but their number increased sharply from the 1980s onward (78.2 +/- 25.65 and 147.2 +/- 66.89, respectively, during the 1980s, 126.2 +/- 11.94 and 301.4 +/- 35.99, respectively, during the 1990s, and 113.3 +/- 36.46 and 287.3 +/- 85.93, respectively, during the 2000s). The difference between the decades of 1960s-2000s, with respect to the number of publishing journals and published articles, was highly significant (P < 0.0001). Only 90 (10.6%) of the journals were from the arena of pathology and its branches. The remaining journals belonged to various other disciplines of medicine; a small fraction were even from the veterinary sciences. Ten journals, including three in the field of cytopathology, published 2,448 (43.6%) of the total articles on FNA. During 1987-2002, 46 (29.7%) of the 155 developing nations published articles on FNA, whereas 28 (52.8%) of the developed (high-income economies) countries did so, the difference being highly significant (P = 0.0044). The total number of publications from high-income economies was 3,124 (195.3 per year), as

  13. Experiments on selection of feeding site and food size in oystercatchers, Haematopus ostralegus, of different social status

    NASA Astrophysics Data System (ADS)

    Leopold, M. F.; Swennen, C.; De Bruijn, L. L. M.

    Oystercatchers, Haematopus ostralegus, were tested for size selection in two prey species, cockles ( Cerastoderma edule) and mussels ( Mytilus edulis), under semi-natural, but strictly experimental, conditions that allowed recovery of all shells of prey items eaten. Within any patch of cockles offered, size was not an important selection criterion for the birds. The mean length of cockles consumed always differed less than 1 mm (the measuring accuracy) from the mean length of the cockles presented. When given a choice between patches of different prey quality, the birds tended to select patches according to their relative dominance status, with the most dominant bird feeding mainly in the patch where the prey items had the largest flesh contents. Less dominant birds were forced out of the preferred patch and obtained most of theif food from a patch of presumedly lower quality. One of these birds adapted its prey-handling method and its bill shape for efficient feeding in such a low quality pathc, and it continued feeding in that patch, even after the dominant conspecifics had been removed. In experiments with mussels as prey, the test bird did not select primarily on the basis of size but tended to eat those mussels that were easiest to open. It is concluded that size selection in oystercatchers that eat either cockles or mussels ends with the choice of a certain foraging patch. Within a patch of cockles of one year-class, which is the field condition for the majority of oystercatchers in the Wadden Sea, no selection for size occurs, because this would take too much extra searching time to be profitable.

  14. Radiation Therapy Infrastructure and Human Resources in Low- and Middle-Income Countries: Present Status and Projections for 2020

    SciTech Connect

    Datta, Niloy R.; Samiei, Massoud; Bodis, Stephan

    2014-07-01

    Purpose: Radiation therapy, a key component of cancer management, is required in more than half of new cancer patients, particularly in low- and middle-income countries (LMICs). The projected rise in cancer incidence over the next decades in LMICs will result in an increasing demand for radiation therapy services. Considering the present cancer incidence and that projected for 2020 (as listed in GLOBOCAN), we evaluated the current and anticipated needs for radiation therapy infrastructure and staffing by 2020 for each of the LMICs. Methods and Materials: Based on World Bank classification, 139 countries fall in the category of LMICs. Details of teletherapy, radiation oncologists, medical physicists, and radiation therapy technologists were available for 84 LMICs from the International Atomic Energy Agency–Directory of Radiotherapy Centres (IAEA-DIRAC) database. Present requirements and those for 2020 were estimated according to recommendations from the IAEA and European Society for Radiotherapy and Oncology (ESTRO-QUARTS). Results: Only 4 of the 139 LMICs have the requisite number of teletherapy units, and 55 (39.5%) have no radiation therapy facilities at present. Patient access to radiation therapy in the remaining 80 LMICs ranges from 2.3% to 98.8% (median: 36.7%). By 2020, these 84 LMICs would additionally need 9169 teletherapy units, 12,149 radiation oncologists, 9915 medical physicists, and 29,140 radiation therapy technologists. Moreover, de novo radiation therapy facilities would have to be considered for those with no services. Conclusions: Twelve pragmatic steps are proposed for consideration at national and international levels to narrow the gap in radiation therapy access. Multipronged and coordinated action from all national and international stakeholders is required to develop realistic strategies to curb this impending global crisis.

  15. Leptin and its receptors are present in the rat olfactory mucosa and modulated by the nutritional status.

    PubMed

    Baly, Christine; Aioun, Josiane; Badonnel, Karine; Lacroix, Marie-Christine; Durieux, Didier; Schlegel, Claire; Salesse, Roland; Caillol, Monique

    2007-01-19

    Leptin is an adipocyte-derived cytokine that regulates body weight mainly via the long form of the leptin receptor (Ob-Rb). Leptin and its receptors are expressed in several tissues, suggesting that leptin might also be effective peripherally. We hypothesized that, as shown in taste cells, leptin and its receptors isoforms (Ob-Rs) could be present in the rat olfactory mucosa (OM). Using RT-PCR, light and electron microscopy immunohistochemistry (ICC), we found that different isoforms of the receptor were expressed in OM and localized in sustentacular cells and in a subpopulation of maturating neurons; in addition, immunoreactivity was also present in differentiated neurons and enriched at the cilia membranes, where the odorants bind to their receptors. Moreover, using RT-PCR, ICC and RIA measurements, we showed that leptin is synthesized locally in the olfactory mucosa. In addition, we demonstrate that fasting causes a significant enhanced transcription of both leptin and Ob-Rs in rat OM by quantitative RT-PCR data. Altogether, these results strongly suggested that leptin, acting as an endocrine or a paracrine factor, could be an important regulator of olfactory function, as a neuromodulator of the olfactory message in cilia of mature olfactory receptors neurons (ORN), but also for the homeostasis of this complex tissue, acting on differentiating neurons and on sustentacular cells.

  16. [The status of women and fertility: the experience of developed countries].

    PubMed

    Blayo, C

    1985-01-01

    The author critically examines recent studies that have cited various changes in women's status in developed countries as the cause of changes in the number of children desired. It is suggested that "the number has decreased as a consequence of the social pressures tending to limit the total fertility of women so as to be compatible with the new behaviour patterns of an industrialized society." (summary in ENG, ITA)

  17. Herbaceous crops for energy in Italy: Present status of the research program promoted by ENEL (Italian Electric Company)

    SciTech Connect

    Schenone, G.

    1996-12-31

    The paper presents a synthesis of the main results of the research program promoted by ENEL (Italian Electric Company) on herbaceous energy crops. The objective of the program is to evaluate the potentials of different species and cultivars for biomass fuel production in Italy. For the most promising species, all the links of the chain from cultivation to delivery at the plant gate at the lowest possible cost have to be organized. So far the following species gave annual productivities above 20 dry tons/ha: fiber sorghum (Sorghum sp.); miscanthus (Miscanthus sinensis); and giant reed (Arundo donax). The highest biomass yields, well above 40 dry tons/ha in several trials, were given by giant reed.

  18. Dioxin emissions from thermal waste management in Medellín, Colombia: present regulation status and preliminary results.

    PubMed

    Aristizábal, B; Cobo, M; de Correa, C Montes; Martínez, K; Abad, E; Rivera, J

    2007-01-01

    Preliminary results of a study undertaken to characterize dioxin and furan releases from waste incineration plants operating in Medellín-Colombia are presented. Emission and fly ash samples were collected from representative plants burning medical and industrial residues to characterize PCDD/PCDF levels. Analyses were carried out following European standards for stationary gas emissions EN-1948:1996 and US EPA 1613 (fly ashes). Final extracts were analyzed by both high resolution gas chromatography coupled to high resolution mass spectrometry (HRGC-HRMS) and high resolution gas chromatography coupled to ion trap tandem mass spectrometry (HRGC-ITMS/MS). Preliminary results revealed emission levels of 1-30.3 ng I-TEQ/Nm3 depending on whether or not an air pollution control system (APCS) was installed. Fly ashes contained 8.5-68 ng I-TEQ/g. Critical issues that should be addressed in an assessment and in developing waste management plans in Colombia are discussed.

  19. Severe Acute Malnutrition in Childhood: Hormonal and Metabolic Status at Presentation, Response to Treatment, and Predictors of Mortality

    PubMed Central

    Bartz, Sarah; Mody, Aaloke; Hornik, Christoph; Bain, James; Muehlbauer, Michael; Kiyimba, Tonny; Kiboneka, Elizabeth; Stevens, Robert; Bartlett, John; St Peter, John V.; Newgard, Christopher B.

    2014-01-01

    Objective: Malnutrition is a major cause of childhood morbidity and mortality. To identify and target those at highest risk, there is a critical need to characterize biomarkers that predict complications prior to and during treatment. Methods: We used targeted and nontargeted metabolomic analysis to characterize changes in a broad array of hormones, cytokines, growth factors, and metabolites during treatment of severe childhood malnutrition. Children aged 6 months to 5 years were studied at presentation to Mulago Hospital and during inpatient therapy with milk-based formulas and outpatient supplementation with ready-to-use food. We assessed the relationship between baseline hormone and metabolite levels and subsequent mortality. Results: Seventy-seven patients were enrolled in the study; a subset was followed up from inpatient treatment to the outpatient clinic. Inpatient and outpatient therapies increased weight/height z scores and induced striking changes in the levels of fatty acids, amino acids, acylcarnitines, inflammatory cytokines, and various hormones including leptin, insulin, GH, ghrelin, cortisol, IGF-I, glucagon-like peptide-1, and peptide YY. A total of 12.2% of the patients died during hospitalization; the major biochemical factor predicting mortality was a low level of leptin (P = .0002), a marker of adipose tissue reserve and a critical modulator of immune function. Conclusions: We have used metabolomic analysis to provide a comprehensive hormonal and metabolic profile of severely malnourished children at presentation and during nutritional rehabilitation. Our findings suggest that fatty acid metabolism plays a central role in the adaptation to acute malnutrition and that low levels of the adipose tissue hormone leptin associate with, and may predict, mortality prior to and during treatment. PMID:24606092

  20. TeV/m Nano-Accelerator: Current Status of CNT-Channeling Acceleration Experiment

    SciTech Connect

    Shin, Young Min; Lumpkin, Alex H.; Thangaraj, Jayakar Charles; Thurman-Keup, Randy Michael; Shiltsev, Vladimir D.

    2014-09-17

    Crystal channeling technology has offered various opportunities in the accelerator community with a viability of ultrahigh gradient (TV/m) acceleration for future HEP collider. The major challenge of channeling acceleration is that ultimate acceleration gradients might require a high power driver in the hard x-ray regime (~ 40 keV). This x-ray energy exceeds those for x-rays as of today, although x-ray lasers can efficiently excite solid plasma and accelerate particles inside a crystal channel. Moreover, only disposable crystal accelerators are possible at such high externally excited fields which would exceed the ionization thresholds destroying the atomic structure, so acceleration will take place only in a short time before full dissociation of the lattice. Carbon-based nanostructures have great potential with a wide range of flexibility and superior physical strength, which can be applied to channeling acceleration. This paper presents a beam- driven channeling acceleration concept with CNTs and discusses feasible experiments with the Advanced Superconducting Test Accelerator (ASTA) in Fermilab.

  1. Status of the KATRIN experiment and prospects to search for keV-mass sterile neutrinos in tritium β-decay

    SciTech Connect

    Mertens, Susanne

    2015-03-24

    In this contribution the current status and future perspectives of the Karlsruhe Tritium Neutrino (KATRIN) Experiment are presented. The prime goal of this single β-decay experiment is to probe the absolute neutrino mass scale with a sensitivity of 200 meV (90% CL). We discuss first results of the recent main spectrometer commissioning measurements, successfully verifying the spectrometer’s basic vacuum, transmission and background properties. We also discuss the prospects of making use of the KATRIN tritium source, to search for sterile neutrinos in the multi-keV mass range constituting a classical candidate for Warm Dark Matter. Due to the very high source luminosity, a statistical sensitivity down to active-sterile mixing angles of sin² θ < 1 · 10⁻⁷ (90% CL) could be reached.

  2. Status of the KATRIN experiment and prospects to search for keV-mass sterile neutrinos in tritium β-decay

    DOE PAGESBeta

    Mertens, Susanne

    2015-03-24

    In this contribution the current status and future perspectives of the Karlsruhe Tritium Neutrino (KATRIN) Experiment are presented. The prime goal of this single β-decay experiment is to probe the absolute neutrino mass scale with a sensitivity of 200 meV (90% CL). We discuss first results of the recent main spectrometer commissioning measurements, successfully verifying the spectrometer’s basic vacuum, transmission and background properties. We also discuss the prospects of making use of the KATRIN tritium source, to search for sterile neutrinos in the multi-keV mass range constituting a classical candidate for Warm Dark Matter. Due to the very high sourcemore » luminosity, a statistical sensitivity down to active-sterile mixing angles of sin² θ < 1 · 10⁻⁷ (90% CL) could be reached.« less

  3. Significance, Present Status and Perspectives of the Auroral Zone Magnetic Activity Monitoring by the Russian Arctic Magnetometer Network

    NASA Astrophysics Data System (ADS)

    Troshichev, O. A.; Janzhura, A. S.; Takahashi, K.

    2010-12-01

    The Roshydromet magnetometer network in Russian Arctica includes the following stations: Amderma, Dickson, Cape Chelyuskin, Tiksi, Pevek, Lovozero, Heiss Island, Vieze Island, Izvestia Island. Vitality of the first 5 of them, providing the data for derivation AE/AL/AU indices, was supported during the previous years by the International project Rapidmag (Russian Auroral and Polar Ionospheric Disturbance Magnetometers). In last two years the Roshydromet network in Arctica was subjected to reconstruction. Renovation includes construction of new polar station buildings, deployment of the satellite communication system at stations, and arrangement of new acquisition system for magnetometers. The reconstruction should ensure on-line transmission of the current magnetic data from the Arctic network to AARI and analysis of these data in the near-real time. The present state of affairs and further perspectives are discussed. Examples are given, which show that run of the AL and AU indices, derived with allowance of data from Russian Arctic stations and without this information, can be principally different in case of the strong saw-tooth magnetic substorms.

  4. The SEIS Experiment for the InSight mission: status and performance expectations

    NASA Astrophysics Data System (ADS)

    Mimoun, David; Lognonne, Philippe; Banerdt, W. Bruce; Laudet, Philippe; De Raucourt, Sébastien; IJpelaan, Frans; Kerjean, Laurent; Perez, Rene; Pont, Gabriel; Sylvestre-Baron, Annick; verdier, Nicolas; Denise, Robert; Feldman, Jason; Hurst, Ken; Klein, Kerry; Giardini, Domenico; Zweifel, Peter; Pike, W. Tom; Calcutt, Simon; Bramanti, Christina

    2015-04-01

    The Insight NASA Discovery mission, led by the Jet Propulsion Laboratory, will deploy in September 2016 a very broadband seismometer on the Mars surface, SEIS (Seismic Experiment for Interior Structure). It is a hybrid 3-axes instrument, which encloses 3 very broadband oblique sensors and 3 short period sensors. The sensor assembly and its wind and thermal shield will by deployed on the Mars surface from the Phoenix-like spacecraft by a robotic arm (IDS). The acquisition system will be hosted in the spacecraft warm electronics box, and connected to the deployed sensor assembly by a tether. The SEIS experiment is provided by CNES, the French Space Agency that makes the coordination of a wide consortium including IPGP of Paris (SEIS PI Institution), Imperial College of London, Oxford University, MPS of Göttingen, ETH of Zürich, ISAE from Toulouse and the Jet Propulsion Laboratory of Pasadena. In addition to the seismometer, the Insight payload will also include a suite of instruments complementary to the seismometer, such as a precision temperature sensor, a micro-barometer, a magnetometer and a wind sensor, making it the first geophysical multi-parameter station on another planet. A heat flow sensor and geodetic measurements will provide additional science measurements, in order to constrain the internal structure of Mars. Several challenges have been overcome to design and realize the planetary seismometer, which will exhibit a noise of about 10-9 m/s2/sqrt(Hz) in its seismic bandwidth bandwidth (0.01-1 Hz) for the very broadband component. These challenges include a very efficient insulation from the external temperature variations, and a finely crafted mechanical design to keep the extreme sensitivity of the seismometer, while allowing enough robustness for the harsh mechanical environment encountered during the launch and landing sequences. Also, specific attention has been paid to understanding the various environment contributions to the noise figure. A

  5. [Present status and tasks for genetic testing and risk-reducing surgery in patients with hereditary breast and ovarian cancer].

    PubMed

    Arai, Masami; Taki, Keiko; Iwase, Haruko; Takizawa, Ken; Nishimura, Seiichiro; Iwase, Takuji

    2012-04-01

    In Japan, awareness of hereditary breast and ovarian cancer (HBOC) has gradually increased among health care workers and the general population. We focus on two current topics: genetic testing and risk-reducing surgery for HBOC. Genetic testing for BRCA1 and BRCA2, the genes responsible for HBOC, is performed to diagnose HBOC. PCR-direct sequencing is a standard method used for BRCA1/2 mutation analysis. Recently, genetic rearrangement of BRCA1 was reported in a Japanese patient with HBOC. Therefore, MLPA tests are also being included in routine genetic testing for the disease. The result of "uncertain significance, " which indicates unclear pathogenic significance, is obtained in about 3% of all patients who undergo BRCA1/2 genetic tests. Furthermore, novel candidate genes for HBOC, such as RAD51C, PALB2, and BRIP1, were recently identified. Prophylactic surgical intervention for HBOC includes procedures such as risk-reducing bilateral salpingo-oophorectomy (RRSO) and risk-reducing mastectomy(RRM). In Japan, RRSO is performed in very few patients at present. Increasing evidence from overseas indicates that RRSO contributes to a decreased incidence of ovarian/breast cancers and lowers overall mortality. Therefore, a system for performing RRSO was established in our institute. RRSO was approved to be performed as a clinical examination by our Institutional Review Board. The clinical significance of ipsilateral complete mastectomy and RRM remains unclear. Based on the NCCN guidelines, conservative mastectomy with radiation therapy is relatively contraindicated in patients with HBOC. However, several studies have reported that conservative mastectomy with radiation the rapydoes not increase the incidence of recurrent or metachronous breast cancers in the ipsilateral breast of mutation-positive patients when compared to mutation-negative or control patients. However, more aggressive malignancies seem to be included in the mutation-positive group(especially BRCA1

  6. Status of the Jefferson Lab Polarized Beam Physics Program and Preparations for Upcoming Parity Experiments

    SciTech Connect

    J. Grames; P. Adderley; M. Baylac; J. Clark; A. Day; J. Hansknecht; M. Poelker; M. Stutzman

    2003-07-01

    An ambitious nuclear physics research program continues at Jefferson Lab with Users at three experiment halls receiving reliable, highly polarized electrons at currents to 100 {micro}A. The polarized photoguns and drive lasers that contribute to Jefferson Lab's success will be described as well as significant events since PES2000. Typical of conditions at accelerators worldwide, success brings new challenges. Beam quality specifications continue to become more demanding as Users conduct more challenging experiments. In the months that follow this workshop, two parity violation experiments will begin at Jefferson Lab, G0 and HAPPEx2. The photogun requirements for these experiments will be discussed as well as our plans to eliminate/minimize systematic errors. Recent efforts to construct high power Ti-Sapphire drive lasers for these experiments also will be discussed.

  7. Experiments in free shear flows: Status and needs for the future

    NASA Technical Reports Server (NTRS)

    Kline, S. J.; Coles, D. E.; Eggers, J. M.; Harsha, P. T.

    1973-01-01

    Experiments in free turbulent flows are recommended with the primary concern placed on classical flows in order to augment understanding and for model building. Five classes of experiments dealing with classical free turbulent flows are outlined and proposed as being of particular significance for the near future. These classes include the following: (1) Experiments clarifying the effect of density variation owing to use of different gases, with and without the additional effect of density variation due to high Mach number or other effects; (2) experiments clarifying the role and importance of various parameters which determine the behavior of the near field as well as the condictions under which any of these parameters can be neglected; (3) experiments determining the cumulative effect of initial conditions in terms of distance to fully established flow; (4) experiments for cases where two layers of distinctly different initial turbulence structure flow side by side at the same mean speed; and (5) experiment using contemporary experimental techniques to study structure in free turbulent shear flows in order to compliment and support contemporary work on boundary layers.

  8. Work experience and drinking behavior: alienation, occupational status, workplace drinking subculture and problem drinking.

    PubMed

    Yang, M J; Yang, M S; Kawachi, I

    2001-07-01

    This study explored the association between alienating job conditions and problem drinking within the context of occupational status and workplace drinking subculture. From December 1994 to March 1995, a questionnaire survey was implemented in the manufactory sector in southern Taiwan. Within the questionnaire, any perceived self-estrangement, powerlessness and social isolation that the individual experienced in his work were measured as the alienating job conditions, and any negative physical, psychological and social consequences the individual experienced during the previous month were considered as affecting problem drinking. Of the 1117 subjects, 668 (61.8%) reported imbibing one or more drinks during the preceding month; the average daily alcohol consumption being 0.2+/-0.9 drinks. In addition, 188 (16.8%) subjects reported having experienced drinking-related problems in the preceding month. Workers with low occupational status were more likely to become problem drinkers when they felt comparatively self-estranged in their work. Further, those with a family history including any habitual drinker or those under more encouraging workplace drinking subculture were more likely to have drinking-related problems. For the prevention of problem-related drinking behavior, the workplace should be considered as the focus of our future intervention and management program.

  9. Results and Status of the T2K and NOvA long-baseline neutrino experiments

    NASA Astrophysics Data System (ADS)

    Muether, Mathew

    2016-03-01

    The discovery of neutrino oscillations and the resulting implication that neutrinos have mass, recently awarded the Nobel Prize in Physics, has bolstered a world-wide effort to exploit this effect as a handle on the properties of neutrinos. In the decades since the initial discovery of neutrino oscillations, great strides have been made in understanding the nature of these elusive particles, yet important and fundamental questions remain open, such as: How are the neutrino masses ordered? And Do neutrinos and antineutrinos oscillate differently? The current generation of accelerator based long-baseline neutrino oscillation experiments, T2K in Japan and NOvA in the United States, are actively pursuing the answers to these questions. In this talk, I will review the recent results and current status of the T2K and NOvA long-baseline neutrino experiments.

  10. The present status of hypnosis

    PubMed Central

    Peterfy, G.

    1973-01-01

    In this brief survey of the medical uses of hypnosis the author attempts to clarify the various theories of hypnosis, indications for its use in medical practice, and applications in the treatment of psychosomatic disorders, psychiatric disorders and in miscellaneous cases. Brief descriptions of a variety of induction methods are given, and the potential hazards of hypnosis are explored. It is the author's impression that the practice of hypnosis has, through the years, been misunderstood and often unjustly discredited. The reputation gained for it by charlatans and well intentioned, though untrained, practitioners, has obscured its value as a therapeutic tool in the eyes of a large segment of the medical profession. Hypnosis, when judiciously utilized by a qualified therapist, may be a valuable addition to the armamentarium of psychotherapeutic treatment methods. PMID:4599597

  11. Language experience shapes early electrophysiological responses to visual stimuli: the effects of writing system, stimulus length, and presentation duration.

    PubMed

    Xue, Gui; Jiang, Ting; Chen, Chuansheng; Dong, Qi

    2008-02-15

    How language experience affects visual word recognition has been a topic of intense interest. Using event-related potentials (ERPs), the present study compared the early electrophysiological responses (i.e., N1) to familiar and unfamiliar writings under different conditions. Thirteen native Chinese speakers (with English as their second language) were recruited to passively view four types of scripts: Chinese (familiar logographic writings), English (familiar alphabetic writings), Korean Hangul (unfamiliar logographic writings), and Tibetan (unfamiliar alphabetic writings). Stimuli also differed in lexicality (words vs. non-words, for familiar writings only), length (characters/letters vs. words), and presentation duration (100 ms vs. 750 ms). We found no significant differences between words and non-words, and the effect of language experience (familiar vs. unfamiliar) was significantly modulated by stimulus length and writing system, and to a less degree, by presentation duration. That is, the language experience effect (i.e., a stronger N1 response to familiar writings than to unfamiliar writings) was significant only for alphabetic letters, but not for alphabetic and logographic words. The difference between Chinese characters and unfamiliar logographic characters was significant under the condition of short presentation duration, but not under the condition of long presentation duration. Long stimuli elicited a stronger N1 response than did short stimuli, but this effect was significantly attenuated for familiar writings. These results suggest that N1 response might not reliably differentiate familiar and unfamiliar writings. More importantly, our results suggest that N1 is modulated by visual, linguistic, and task factors, which has important implications for the visual expertise hypothesis.

  12. The National Criticality Experiments Research Center at the Device Assembly Facility, Nevada National Security Site: Status and Capabilities, Summary Report

    SciTech Connect

    S. Bragg-Sitton; J. Bess; J. Werner

    2011-09-01

    The National Criticality Experiments Research Center (NCERC) was officially opened on August 29, 2011. Located within the Device Assembly Facility (DAF) at the Nevada National Security Site (NNSS), the NCERC has become a consolidation facility within the United States for critical configuration testing, particularly those involving highly enriched uranium (HEU). The DAF is a Department of Energy (DOE) owned facility that is operated by the National Nuclear Security Agency/Nevada Site Office (NNSA/NSO). User laboratories include the Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL). Personnel bring their home lab qualifications and procedures with them to the DAF, such that non-site specific training need not be repeated to conduct work at DAF. The NNSS Management and Operating contractor is National Security Technologies, LLC (NSTec) and the NNSS Safeguards and Security contractor is Wackenhut Services. The complete report provides an overview and status of the available laboratories and test bays at NCERC, available test materials and test support configurations, and test requirements and limitations for performing sub-critical and critical tests. The current summary provides a brief summary of the facility status and the method by which experiments may be introduced to NCERC.

  13. Status and first results of the Canarias infrared camera experiment (CIRCE) for the Gran Telescopio Canarias

    NASA Astrophysics Data System (ADS)

    Garner, Alan; Stelter, Richard D.; Eikenberry, Stephen S.; Lasso-Cabrera, Nestor; Raines, Steven N.; Charcos, Miguel; Edwards, Michelle; Marín-Franch, Antonio; Ackley, Kendall; Cenarro, A. Javier; Bennett, John G.; Chinn, Brian; Frommeyer, Raymond; Herlevich, Michael D.; Miller, Paola; Murphey, Charles H.; Packham, Christopher

    2014-07-01

    CIRCE is a near-infrared (1-2.5 micron) imager, polarimeter and low-resolution spectrograph intended as a visitor instrument for the Gran Telescopio Canarias 10.-4m telescope. It was built largely by graduate students and postdocs, with help from the UF astronomy engineering group, and is funded by the University of Florida and the U.S. National Science Foundation. CIRCE is intended to help fill the gap in time between GTC first light and the arrival of EMIR, and will also provide the following scientific capabilities to compliment EMIR after its arrival: high- resolution imaging, narrowband imaging, high-time-resolution photometry, imaging- and spectro- polarimetry, low-resolution spectroscopy. In this poster, we review the lab testing results for CIRCE from 2013 and describe the instrument status (currently in shipment to GTC).

  14. Status of the NGNP fuel experiment AGR-2 irradiated in the advanced test reactor

    SciTech Connect

    S. Blaine Grover; David A. Petti

    2014-05-01

    The United States Department of Energy's Next Generation Nuclear Plant (NGNP) Advanced Gas Reactor (AGR) Fuel Development and Qualification Program will be irradiating up to seven separate low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States, and will be irradiated over the next several years to demonstrate and qualify new TRISO coated particle fuel for use in high temperature gas reactors. The goals of the irradiation experiments are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of at least six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also undergo on-line fission product monitoring to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006 and was completed in November 2009. The second experiment (AGR-2), which utilized the same experiment design as well as control and monitoring systems as AGR-1, started irradiation in June 2010 and is currently scheduled to be completed in April 2013. The design of this experiment and sup

  15. Experimental Status of Exotic Mesons and the GlueX Experiment

    SciTech Connect

    Daniel Carman

    2006-10-22

    One of the unanswered and most fundamental questions in physics regards the nature of the confinement mechanism of quarks and gluons in QCD. Exotic hybrid mesons manifest gluonic degrees of freedom and their spectroscopy will provide the data necessary to test assumptions in lattice QCD and the specific phenomenology leading to confinement. Within the past two decades a number of experiments have put forth tantalizing evidence for the existence of exotic hybrid mesons in the mass range below 2 GeV. This talk represents an overview of the available data and what has been learned. In looking toward the future, the GlueX experiment at Jefferson Laboratory represents a new initiative that will perform detailed spectroscopy of the light-quark meson spectrum. This experiment and its capabilities will be reviewed.

  16. Preparation Status of Payload Operations for the First Experiment in JEM

    NASA Astrophysics Data System (ADS)

    Wakatsuki, Takao; Nishikawa, Waka; Kobayashi, Ryoji

    Japan Aerospace Exploration Agency (JAXA) is now preparing the first utilization activities in “KIBO”. JAXA already completed the hardware productions of the first experiment facilities and succeeded their launch to the International Space Station in March 2008. JAXA plans the fluid physics and material science experiments, several lifescience experiments, measurement of the radiation environment in “KIBO”, demonstration of high definition television system, some educational and commercial programs in 2008. Most of the preparation works of making the operational products for the execution of each activity have already done. The setup of the ground operation system in JAXA Tsukuba Space Center for KIBO operation was completed and the end to end communication data flow was validated. The establishment of a JAXA payload flight controller team are also undergoing right now and the general training of the team has completed.

  17. Status of ATR-A1 irradiation experiment on vanadium alloys and low-activation steels

    SciTech Connect

    Tsai, H.; Strain, R.V.; Gomes, I.; Chung, H.; Smith, D.L.

    1997-04-01

    The ATR-A1 irradiation experiment in the Advanced Test Reactor (ATR) was a collaborative U.S./Japan effort to study at low temperatures the effects of neutron damage on vanadium alloys. The experiment also contained a limited quantity of low-activation ferritic steel specimens from Japan as part of the collaboration agreement. The irradiation was completed on May 5, 1996, as planned, after achieving an estimated neutron damage of 4.7 dpa in vanadium. The capsule has since been kept in the ATR water canal for the required radioactivity cool-down. Planning is underway for disassembly of the capsule and test specimen retrieval.

  18. Female work experience, employment status, and birth expectations: sequential decision-making in the Philippines.

    PubMed

    Rosenzweig, M R

    1976-08-01

    The influence of women's birth parity and accumulated market skills on their current labor force participation and birth expectations is examined within a sequential choice framework. Analysis of household data from the 1973 Philippines National Demographic Survey suggests these patterns: (a) women who have accumulated larger families work less in the current period and anticipate fewer additional births; (b) women with more past work experience tend to work more hours in the current period; and (c) work experience appears to have only a weak negative effect on birth expectations among older women.

  19. The Stratospheric Aerosol and Gas Experiment III/International Space Station Mission: Science Objectives and Mission Status

    NASA Astrophysics Data System (ADS)

    Eckman, R.; Zawodny, J. M.; Cisewski, M. S.; Flittner, D. E.; McCormick, M. P.; Gasbarre, J. F.; Damadeo, R. P.; Hill, C. A.

    2015-12-01

    The Stratospheric Aerosol and Gas Experiment III/International Space Station (SAGE III/ISS) is a strategic climate continuity mission which was included in NASA's 2010 plan, "Responding to the Challenge of Climate and Environmental Change: NASA's Plan for a Climate-Centric Architecture for Earth Observations and Applications from Space." SAGE III/ISS continues the long-term, global measurements of trace gases and aerosols begun in 1979 by SAGE I and continued by SAGE II and SAGE III on Meteor 3M. Using a well characterized occultation technique, the SAGE III instrument's spectrometer will measure vertical profiles of ozone, aerosols, water vapor, nitrogen dioxide, and other trace gases relevant to ozone chemistry. The mission will launch in 2016 aboard a Falcon 9 spacecraft.The primary objective of SAGE III/ISS is to monitor the vertical distribution of aerosols, ozone, and other trace gases in the Earth's stratosphere and troposphere to enhance our understanding of ozone recovery and climate change processes in the stratosphere and upper troposphere. SAGE III/ISS will provide data necessary to assess the state of the recovery in the distribution of ozone, extend the SAGE III aerosol measurement record that is needed by both climate models and ozone models, and gain further insight into key processes contributing to ozone and aerosol variability. The multi-decadal SAGE ozone and aerosol data sets have undergone intense community scrutiny for accuracy and stability. SAGE ozone data have been used to monitor the effectiveness of the Montreal Protocol.The ISS inclined orbit of 51.6 degrees is ideal for SAGE III measurements because the orbit permits solar occultation measurement coverage to approximately +/- 70 degrees of latitude. SAGE III/ISS will make measurements using the solar occultation measurement technique, lunar occultation measurement technique, and the limb scattering measurement technique. In this presentation, we describe the SAGE III/ISS mission, its

  20. [Internet-based Continuing Medical Education. Presentation of the first experience of the Spanish Society of Internal Medicine].

    PubMed

    San José, A; Formiga, F; López Soto, A; Ortiz, J; Tiberio, G; Ollero, M; Valero, J; Ballarín, M

    2010-12-01

    This paper presents the first experience of the Spanish Society of Internal Medicine in the development of an Internet-based Continuing Medical Education program for Society members, accredited by the Health Ministry and the Autonomous University of Barcelona, and funded by the Menarini Group SA. Academic performance and satisfaction of participants in this course have been very satisfactory, both with respect to scientific content and the virtual learning environment. This experience shows that Internet-based continuing medical education is a field with a great future that is well accepted by participating physicians, and that the scientific societies, with the collaboration of other institutions and companies, can lead Internet-based Continuing Medical Education programs especially designed and tailored to their members.

  1. Design and Status of the NGNP Fuel Experiment AGR-3/4 Irradiated in the Advanced Test Reactor

    SciTech Connect

    Blaine Grover

    2012-10-01

    significantly different from the first two experiments, though the control and monitoring systems are very similar. The purpose and design of this experiment will be discussed followed by its progress and status to date.

  2. The Influence of Student Status on Student Interactions and Experiences during a Sport Education Unit

    ERIC Educational Resources Information Center

    Brock, Sheri J.; Rovegno, Inez; Oliver, Kimberly L.

    2009-01-01

    Background: Curriculum models that include group work and allow student decision-making and responsibility within physical education classes have become increasingly popular. Models such as Sport Education are likely to facilitate different and potentially better quality experiences for students. One of the underlying premises of Sport Education…

  3. Status of the MACRO experiment at Gran Sasso. [Monopole Astrophysics and Cosmic Ray Observatory

    NASA Technical Reports Server (NTRS)

    Ahlen, Steve

    1990-01-01

    The design of the MACRO (Monopole Astrophysics and Cosmic Ray Observatory) experiment is described, and the results achieved by the running of its first supermodule are summarized. Searches for magnetic monopoles and point sources of downward muons resulted in no detections. One upward moving muon was seen along with abundant data on muon bundles.

  4. Status and Prospects of the EDELWEISS-III Direct WIMP Search Experiment

    NASA Astrophysics Data System (ADS)

    Juillard, A.

    2016-08-01

    EDELWEISS-III is a direct dark matter search experiment, running 800 g heat-and-ionization cryogenic germanium detectors equipped with Full InterDigitized electrodes (FID) for the rejection of near-surface events. We report a preliminary analysis for a subset of the data (35 kg\\cdot days) as well as future prospects for low-mass WIMPs seach.

  5. The life experience and status of Chinese rural women from observation of three age groups.

    PubMed

    Dai, K

    1991-03-01

    Interview data gathered during 2 surveys in Anhui and Shejiang Provinces in 1986 and 1987 are used to depict changes in the social status and life situation of rural women in China in 3 age groups, 18-36, 37-55, and 56 and over. For the younger women, marriage increasingly is a result of discussion with parents, not arrangement, but 3rd-party introductions are increasing. They are active in household and township enterprises and aspire to more education and economic independence. The middle-aged group experienced war and revolution and now work nonstop under the responsibility system of household production, aspiring to university education for sons and enterprise work for daughters. The older women, while supported by their sons, live a frugal existence. In general, preference for sons is still prevalent and deep-seated. At the same time, the bride price and costs of marriage are increasing and of widespread concern. Rural socioeconomic growth is required before Confucian traditions are overcome. PMID:12179888

  6. Status of ATR-A1 irradiation experiment on vanadium alloys and low-activation steels

    SciTech Connect

    Tsai, H.; Strain, R.V.; Gomes, I.; Smith, D.L.; Matsui, H.

    1996-10-01

    The ATR-A1 irradiation experiment was a collaborative U.S./Japan effort to study at low temperature the effects of neutron damage on vanadium alloys. The experiment also contained a limited quantity of low-activation ferritic steel specimens from Japan as part of the collaboration agreement. The irradiation started in the Advanced Test Reactor (ATR) on November 30, 1995, and ended as planned on May 5, 1996. Total exposure was 132.9 effective full power days (EFPDs) and estimated neutron damage in the vanadium was 4.7 dpa. The vehicle has been discharged from the ATR core and is scheduled to be disassembled in the next reporting period.

  7. Status and Plans for the FLARE (Facility for Laboratory Reconnection Experiments) Project

    NASA Astrophysics Data System (ADS)

    Ji, H.; Bhattacharjee, A.; Prager, S.; Daughton, W.; Bale, S.; Carter, T.; Crocker, N.; Drake, J.; Egedal, J.; Sarff, J.; Wallace, J.; Chen, Y.; Cutler, R.; Fox, W.; Heitzenroeder, P.; Kalish, M.; Jara-Almonte, J.; Myers, C.; Ren, Y.; Yamada, M.; Yoo, J.

    2015-11-01

    The FLARE device (flare.pppl.gov) is a new intermediate-scale plasma experiment under construction at Princeton to study magnetic reconnection in regimes directly relevant to space, solar, astrophysical, and fusion plasmas. The existing small-scale experiments have been focusing on the single X-line reconnection process either with small effective sizes or at low Lundquist numbers, but both of which are typically very large in natural and fusion plasmas. The design of the FLARE device is motivated to provide experimental access to the new regimes involving multiple X-lines, as guided by a reconnection ``phase diagram'' [Ji & Daughton, PoP (2011)]. Most of major components of the FLARE device have been designed and are under construction. The device will be assembled and installed in 2016, followed by commissioning and operation in 2017. The planned research on FLARE as a user facility will be discussed. Supported by NSF.

  8. Factors Associated with the Disposition of Severely Injured Patients Presenting to Non-Trauma Center Emergency Departments: Disparities by Insurance Status

    PubMed Central

    Delgado, M. Kit; Yokell, Michael A.; Staudenmayer, Kristan L.; Spain, David A.; Hernandez-Boussard, Tina; Wang, N. Ewen

    2014-01-01

    Importance Trauma is the leading cause of potential years of life lost before age 65 in the U.S. Timely care in a designated trauma center has been shown to reduce mortality by 25%. However, many severely injured patients are not transferred to trauma centers after initially presenting to non-trauma centers. Objective Determine patient and hospital level factors associated with the decision to admit rather than transfer severely injured patients who present to non-trauma center emergency departments (EDs). We hypothesized that insured patients would be more likely to be admitted than transferred compared to patients without insurance. Design, Setting, and Participants Retrospective analysis of the 2009 Nationwide Emergency Department Sample. We included all ED encounters for major trauma (injury severity score [ISS] > 15) seen at non-trauma centers in patients aged 18–64. We excluded ED discharges and ED deaths. We quantified the absolute risk difference between admission vs. transfer by insurance status while adjusting for age, sex, injury severity, injury mechanism, weekend admission, month, urban-rural status and median income of home zip code, ED volume and teaching status, and U.S. region Main Outcome Measures Inpatient admission vs. transfer to another acute care facility. Results There were 4,513 observations from 636 non-trauma centers for analysis, representing a nationally weighted population of 19,312 non-trauma center ED encounters for major trauma in 2009. In 2009 54.5% were admitted at the non-trauma center. Compared to the uninsured, the adjusted absolute risk of admission vs. transfer was 14.2% higher (95% CI: 9.2, 19.4) for patients with Medicaid and 11.1 % higher (95% CI: 6.9, 15.4) for patients with private insurance. Other factors associated with admission vs. transfer included severe abdominal injuries (risk difference 15.8%,95% CI: 9.3, 22.3) urban teaching hospital vs. non-teaching hospital ((26.2%,15.2, 37.2), and ED volume (3.4% higher

  9. Status of lithium-filled specimen subcapsules for the HFIR-MFE-RB10J experiment

    SciTech Connect

    Robertson, J.P.; Howell, M.; Lenox, K.E.

    1998-09-01

    The HFIR-MFE-RB-10J experiment will be irradiated in a Removable Beryllium position in the HFIR for 10 reactor cycles, accumulating approximately 5 dpa in steel. The upper region of the capsule contains two lithium-filled subcapsules containing vanadium specimens. This report describes the techniques developed to achieve a satisfactory lithium fill with a specimen occupancy of 26% in each subcapsule.

  10. Feeling Present in Arousing Virtual Reality Worlds: Prefrontal Brain Regions Differentially Orchestrate Presence Experience in Adults and Children

    PubMed Central

    Baumgartner, Thomas; Speck, Dominique; Wettstein, Denise; Masnari, Ornella; Beeli, Gian; Jäncke, Lutz

    2008-01-01

    Virtual reality (VR) is a powerful tool for simulating aspects of the real world. The success of VR is thought to depend on its ability to evoke a sense of “being there”, that is, the feeling of “Presence”. In view of the rapid progress in the development of increasingly more sophisticated virtual environments (VE), the importance of understanding the neural underpinnings of presence is growing. To date however, the neural correlates of this phenomenon have received very scant attention. An fMRI-based study with 52 adults and 25 children was therefore conducted using a highly immersive VE. The experience of presence in adult subjects was found to be modulated by two major strategies involving two homologous prefrontal brain structures. Whereas the right DLPFC controlled the sense of presence by down-regulating the activation in the egocentric dorsal visual processing stream, the left DLPFC up-regulated widespread areas of the medial prefrontal cortex known to be involved in self-reflective and stimulus-independent thoughts. In contrast, there was no evidence of these two strategies in children. In fact, anatomical analyses showed that these two prefrontal areas have not yet reached full maturity in children. Taken together, this study presents the first findings that show activation of a highly specific neural network orchestrating the experience of presence in adult subjects, and that the absence of activity in this neural network might contribute to the generally increased susceptibility of children for the experience of presence in VEs. PMID:18958209

  11. Status and Planned Experiments of the Hiradmat Pulsed Beam Material Test Facility at CERN SPS

    SciTech Connect

    Charitonidis, Nikolaos; Efthymiopoulos, Ilias; Fabich, Adrian; Meddahi, Malika; Gianfelice-Wendt, Eliana

    2015-06-01

    HiRadMat (High Irradiation to Materials) is a facility at CERN designed to provide high-intensity pulsed beams to an irradiation area where material samples as well as accelerator component assemblies (e.g. vacuum windows, shock tests on high power targets, collimators) can be tested. The beam parameters (SPS 440 GeV protons with a pulse energy of up to 3.4 MJ, or alternatively lead/argon ions at the proton equivalent energy) can be tuned to match the needs of each experiment. It is a test area designed to perform single pulse experiments to evaluate the effect of high-intensity pulsed beams on materials in a dedicated environment, excluding long-time irradiation studies. The facility is designed for a maximum number of 1016 protons per year, in order to limit the activation of the irradiated samples to acceptable levels for human intervention. This paper will demonstrate the possibilities for research using this facility and go through examples of upcoming experiments scheduled in the beam period 2015/2016.

  12. Fighting experience alters brain androgen receptor expression dependent on testosterone status

    PubMed Central

    Li, Cheng-Yu; Earley, Ryan L.; Huang, Shu-Ping; Hsu, Yuying

    2014-01-01

    Contest decisions are influenced by the outcomes of recent fights (winner–loser effects). Steroid hormones and serotonin are closely associated with aggression and therefore probably also play important roles in mediating winner–loser effects. In mangrove rivulus fish, Kryptolebias marmoratus, individuals with higher testosterone (T), 11-ketotestosterone and cortisol levels are more capable of winning, but titres of these hormones do not directly mediate winner–loser effects. In this study, we investigated the effects of winning/losing experiences on brain expression levels of the receptor genes for androgen (AR), oestrogen α/β (ERα/β), glucocorticoid (GR) and serotonin (5-HT1AR). The effect of contest experience on AR gene expression depended on T levels: repeated losses decreased, whereas repeated wins increased AR gene expression in individuals with low T but not in individuals with medium or high T levels. These results lend strong support for AR being involved in mediating winner–loser effects, which, in previous studies, were more detectable in individuals with lower T. Furthermore, the expression levels of ERα/β, 5-HT1AR and GR genes were higher in individuals that initiated contests against larger opponents than in those that did not. Overall, contest experience, underlying endocrine state and hormone and serotonin receptor expression patterns interacted to modulate contest decisions jointly. PMID:25320171

  13. [NUTRITIONAL STATUS IN THE EXPERIMENT WITH 105-DAY ISOLATION AS THE FIRST PHASE OF PROJECT MARS-500].

    PubMed

    Agureev, A N; Afonin, B V; Sedova, E A; Solovieva, A A; Valuev, V A; Sidorenko, L A

    2015-01-01

    In a 105-day experiment simulating crew life in a space exploration vehicle, shifts in the nutritional status were assessed in 6 test subjects differing in the body mass index, basal metabolism, attitude to the diet, physical exercise and workload. Results of the investigation showed that because of the hard physical work the nutritional status of test subjects was described by more intensive basal metabolism, elevated metabolism of carbohydrates and lipids, and their increased mobilization from depots. Food ration, though it was sufficient to sustain health and fairly high performance, failed to meet fully individual taste preferences and energy needs for physical activities. The heavy workloads required mobilization of lipids from adipose depots, and a decrease of the hepatic detoxification and metabolic capacities. Self-limitation of eating protein-rich desserts led to a relative deficiency of protein intake. These faults of the diet were the reason why 4 out of 6 test subjects reduced their basal metabolism and lost body mass. Recovery of metabolism and slowdown of the body mass loss were achieved by supplementing meals with available protein-containing products.

  14. [NUTRITIONAL STATUS IN THE EXPERIMENT WITH 105-DAY ISOLATION AS THE FIRST PHASE OF PROJECT MARS-500].

    PubMed

    Agureev, A N; Afonin, B V; Sedova, E A; Solovieva, A A; Valuev, V A; Sidorenko, L A

    2015-01-01

    In a 105-day experiment simulating crew life in a space exploration vehicle, shifts in the nutritional status were assessed in 6 test subjects differing in the body mass index, basal metabolism, attitude to the diet, physical exercise and workload. Results of the investigation showed that because of the hard physical work the nutritional status of test subjects was described by more intensive basal metabolism, elevated metabolism of carbohydrates and lipids, and their increased mobilization from depots. Food ration, though it was sufficient to sustain health and fairly high performance, failed to meet fully individual taste preferences and energy needs for physical activities. The heavy workloads required mobilization of lipids from adipose depots, and a decrease of the hepatic detoxification and metabolic capacities. Self-limitation of eating protein-rich desserts led to a relative deficiency of protein intake. These faults of the diet were the reason why 4 out of 6 test subjects reduced their basal metabolism and lost body mass. Recovery of metabolism and slowdown of the body mass loss were achieved by supplementing meals with available protein-containing products. PMID:26934786

  15. Maternal experiences of racial discrimination and child weight status in the first 3 years of life.

    PubMed

    Dixon, B; Rifas-Shiman, S L; James-Todd, T; Ertel, K; Krieger, N; Kleinman, K P; Rich-Edwards, J W; Gillman, M W; Taveras, E M

    2012-12-01

    Among US racial/ethnic minority women, we examined associations between maternal experiences of racial discrimination and child growth in the first 3 years of life. We analyzed data from Project Viva, a pre-birth cohort study. We restricted analyses to 539 mother-infant pairs; 294 were Black, 127 Hispanic, 110 Asian and 8 from additional racial/ethnic groups. During pregnancy, mothers completed the Experiences of Discrimination survey that measured lifetime experiences of racial discrimination in diverse domains. We categorized responses as 0, 1-2 or ≥3 domains. Main outcomes were birth weight for gestational age z-score; weight for age (WFA) z-score at 6 months of age; and at 3 years of age, body mass index (BMI) z-score. In multivariable analyses, we adjusted for maternal race/ethnicity, nativity, education, age, pre-pregnancy BMI, household income and child sex and age. Among this cohort of mostly (58.2%) US-born and economically non-impoverished mothers, 33% reported 0 domains of discrimination, 33% reported discrimination in 1-2 domains and 35% reported discrimination in ≥3 domains. Compared with children whose mothers reported no discrimination, those whose mothers reported ≥3 domains had lower birth weight for gestational age z-score (β -0.25; 95% CI: -0.45, -0.04), lower 6 month WFA z-score (β -0.34; 95% CI: -0.65, -0.03) and lower 3-year BMI z-score (β -0.33; 95% CI: -0.66, 0.00). In conclusion, we found that among this cohort of US racial/ethnic minority women, mothers' report of experiencing lifetime discrimination in ⩾ 3 domains was associated with lower fetal growth, weight at 6 months and 3-year BMI among their offspring.

  16. Effect of Lump Size and Nodal Status on Prognosis in Invasive Breast Cancer: Experience from Rural India

    PubMed Central

    Garg, Monique; Sidhu, Darshan Singh; Singh, Amandeep

    2016-01-01

    Introduction Breast cancer is now the leading cause of cancer among Indian women. Usually large tumour size and axillary lymph node involvement are linked with adverse outcome and this notion forms the basis of screening programs i.e. early detection. Aim The present study was carried out to analyse relationship between tumour size, lymph node status and there relation with outcome after treatment. Materials and Methods Fifty patients with cytology-proven invasive breast tumours were evaluated for size, clinical and pathologic characteristics of tumour, axillary lymph node status and outcome data recorded on sequential follow-up. Results Mean age of all participated patients was 52.24±10 years. Most common tumour location was in the upper outer quadrant with mean size of primary tumour being 3.31±1.80cm. On pathology number of lymph nodes examined ranged from 10 to 24 and 72% of patients recorded presence of disease in axilla. Significant positive correlation (p<0.013; r2=0.026) between tumour size and axillary lymph node involvement on linear regression. Also an indicative correlation between size and grade of tumour and axillary lymph node status was found with survival from the disease. Conclusion The present study highlights that the size of the primary tumour and the number of positive lymph nodes have an inverse linear relationship with prognosis. Despite advances in diagnostic modalities, evolution of newer markers and genetic typing both size of tumour as T and axillary lymphadenopathy as N form an integral part of TNM staging and are of paramount importance for their role in treatment decisions and illustrate prognosis in patients with invasive breast cancer. PMID:27504343

  17. Living with Diabetes: Experiences of Inner and Outer Sources of Beliefs in Women with Low Socioeconomic Status

    PubMed Central

    Boonsatean, Wimonrut; Carlsson, Anna; Östman, Margareta; Rosner, Irena Dychawy

    2016-01-01

    The purpose of this study was to examine the life experiences of nineteen Thai women of low socioeconomic status who were living with type 2 diabetes. A qualitative research design was conducted, and the women were identified by the snowball technique. Data was collected through semi-structured interviews, and processes of induction and abstraction were used for data analysis. The theme “keeping equilibrium of one’s mind” involved two sub-themes: experiencing an unpredictable future and being empowered by emerged beliefs. The first sub-theme encompassed worries concerning health and fears of being a burden to one’s family. The second sub-theme comprised the experiences of continuing life without being conquered by the disease and believing in the natural law described in Buddhist teachings. These findings revealed that participants could maintain a balance among their concerns through empowerment by inner and outer sources of beliefs, particularly in Buddhist teachings. Despite the vulnerable situations caused by diabetes and low socioeconomic status, the women remained calm, with a consciousness to continue their lives with the disease. The Buddhist views on life, specifically natural law, assisted them to consider life with diabetes as simply a natural course. Buddhism served as a spiritual refuge and helped the women to cope with their psychological burden from diabetes. These findings may reflect the need for health care professionals to provide more holistic care that would assist patients to live with their disease. Buddhist beliefs can be used as a tool to assist Thai patients to empower themselves successfully. PMID:27045410

  18. Living with Diabetes: Experiences of Inner and Outer Sources of Beliefs in Women with Low Socioeconomic Status.

    PubMed

    Boonsatean, Wimonrut; Carlsson, Anna; Östman, Margareta; Rosner, Irena Dychawy

    2016-01-01

    The purpose of this study was to examine the life experiences of nineteen Thai women of low socioeconomic status who were living with type 2 diabetes. A qualitative research design was conducted, and the women were identified by the snowball technique. Data was collected through semi-structured interviews, and processes of induction and abstraction were used for data analysis. The theme "keeping equilibrium of one's mind" involved two sub-themes: experiencing an unpredictable future and being empowered by emerged beliefs. The first sub-theme encompassed worries concerning health and fears of being a burden to one's family. The second sub-theme comprised the experiences of continuing life without being conquered by the disease and believing in the natural law described in Buddhist teachings. These findings revealed that participants could maintain a balance among their concerns through empowerment by inner and outer sources of beliefs, particularly in Buddhist teachings. Despite the vulnerable situations caused by diabetes and low socioeconomic status, the women remained calm, with a consciousness to continue their lives with the disease. The Buddhist views on life, specifically natural law, assisted them to consider life with diabetes as simply a natural course. Buddhism served as a spiritual refuge and helped the women to cope with their psychological burden from diabetes. These findings may reflect the need for health care professionals to provide more holistic care that would assist patients to live with their disease. Buddhist beliefs can be used as a tool to assist Thai patients to empower themselves successfully. PMID:27045410

  19. Status Update of the Majorana Demonstrator Neutrinoless Double Beta Decay Experiment

    SciTech Connect

    Gruzko, Julieta; Rielage, Keith Robert; Xu, Wenqin; Elliott, Steven Ray; Massarczyk, Ralph; Goett, John Jerome III; Chu, Pinghan

    2015-11-10

    Neutrinoless double beta decay searches play a major role in determining neutrino properties, in particular the Majorana or Dirac nature of the neutrino and the absolute scale of the neutrino mass. The consequences of these searches go beyond neutrino physics, with implications for Grand Unification and leptogenesis. The Majorana Collaboration is assembling a low-background array of high purity Germanium (HPGe) detectors to search for neutrinoless double-beta decay in 76Ge. The Majorana Demonstrator, which is currently being constructed and commissioned at the Sanford Underground Research Facility in Lead, South Dakota, will contain 44 kg (30 kg enriched in 76Ge) of HPGe detectors. Its primary goal is to demonstrate the scalability and background required for a tonne-scale Ge experiment. This is accomplished via a modular design and projected background of less than 3 cnts/tonne-yr in the region of interest. The experiment is currently taking data with the first of its enriched detectors.

  20. MEGAPIE target design and LiSoR experimentStatus report

    NASA Astrophysics Data System (ADS)

    Auger, T.; Aphecetche, L.; Cadiou, A.; Dai, Y.; Glasbrenner, H.; Gröschel, F.; Kirchner, T.

    2002-09-01

    MEGAPIE is an international project between PSI, CEA, CNRS, ENEA, FZK, JAERI, SCK/CEN, DOE and KAERI to design, build, operate and explore a liquid lead-bismuth spallation target for 1 MW of beam power, taking advantage of the existing spallation neutron facility SINQ at PSI. After a short overview on the MEGAPIE project this paper will concentrate on the material aspects related to the MEGAPIE liquid lead-bismuth target window. The candidate beam window material is a 9Cr-1MoVNb martensitic steel (T91). The LiSoR experiment, being carried out at PSI, simulates severe operating conditions foreseen for future liquid-metal targets such as MEGAPIE in order to validate the material selection relative to irradiation assisted liquid metal corrosion and embrittlement. T91 specimens under stress will be irradiated by 72 MeV protons in flowing liquid lead-bismuth. The experiment will be carried out at the PSI's proton cyclotron INJI. The major goal is to investigate whether corrosion and embrittlement could be enhanced or triggered under representative irradiation conditions.

  1. Status Update on the GPM Ground Validation Iowa Flood Studies (IFloodS) Field Experiment

    NASA Astrophysics Data System (ADS)

    Petersen, Walt; Krajewski, Witold

    2013-04-01

    The overarching objective of integrated hydrologic ground validation activities supporting the Global Precipitation Measurement Mission (GPM) is to provide better understanding of the strengths and limitations of the satellite products, in the context of hydrologic applications. To this end, the GPM Ground Validation (GV) program is conducting the first of several hydrology-oriented field efforts: the Iowa Flood Studies (IFloodS) experiment. IFloodS will be conducted in the central to northeastern part of Iowa in Midwestern United States during the months of April-June, 2013. Specific science objectives and related goals for the IFloodS experiment can be summarized as follows: 1. Quantify the physical characteristics and space/time variability of rain (rates, DSD, process/"regime") and map to satellite rainfall retrieval uncertainty. 2. Assess satellite rainfall retrieval uncertainties at instantaneous to daily time scales and evaluate propagation/impact of uncertainty in flood-prediction. 3. Assess hydrologic predictive skill as a function of space/time scales, basin morphology, and land use/cover. 4. Discern the relative roles of rainfall quantities such as rate and accumulation as compared to other factors (e.g. transport of water in the drainage network) in flood genesis. 5. Refine approaches to "integrated hydrologic GV" concept based on IFloodS experiences and apply to future GPM Integrated GV field efforts. These objectives will be achieved via the deployment of the NASA NPOL S-band and D3R Ka/Ku-band dual-polarimetric radars, University of Iowa X-band dual-polarimetric radars, a large network of paired rain gauge platforms with attendant soil moisture and temperature probes, a large network of both 2D Video and Parsivel disdrometers, and USDA-ARS gauge and soil-moisture measurements (in collaboration with the NASA SMAP mission). The aforementioned measurements will be used to complement existing operational WSR-88D S-band polarimetric radar measurements

  2. The status of the solar neutrino problem and the Russian-American gallium experiment (SAGE)

    SciTech Connect

    Bowles, T.J.

    1994-04-01

    Perhaps the most outstanding discrepancy between prediction and measurements in current particle physics comes from the solar neutrino problem, in which a large deficit of high-energy solar neutrinos is observed. Many Nonstandard Solar Models have been invoked to try to reduce the predicted flux, but all have run into problems in trying to reproduce other measured parameters (e.g., the luminosity) of the Sun. Other explanations involving new physics such as neutrino decay and neutrino oscillations, etc. have also been proffered. Again, most of these explanations have been ruled out by either laboratory or astrophysical measurements. It appears that perhaps the most likely particle physics solution is that of matter enhanced neutrino oscillation, the Mikheyev-Smirnov-Wolfenstein (MSW) oscillations. Two new radiochemical gallium experiments, which have a low enough threshold to be sensitive to the dominant flux of low-energy p-p neutrinos, now also report a deficit and also favor a particle physics solution.

  3. Status of initial testing of the H2SO4 section of the ILS experiment.

    SciTech Connect

    Moore, Robert Charles; Parma, Edward J., Jr.; Gelbard, Fred

    2007-12-01

    A sulfuric acid catalytic decomposer section was assembled and tested for the Integrated Laboratory Scale experiments of the Sulfur-Iodine Thermochemical Cycle. This cycle is being studied as part of the U. S. Department of Energy Nuclear Hydrogen Initiative. Tests confirmed that the 54-inch long silicon carbide bayonet could produce in excess of the design objective of 100 liters/hr of SO{sub 2} at 2 bar. Furthermore, at 3 bar the system produced 135 liters/hr of SO{sub 2} with only 31 mol% acid. The gas production rate was close to the theoretical maximum determined by equilibrium, which indicates that the design provides adequate catalyst contact and heat transfer. Several design improvements were also implemented to greatly minimize leakage of SO{sub 2} out of the apparatus. The primary modifications were a separate additional enclosure within the skid enclosure, and replacement of Teflon tubing with glass-lined steel pipes.

  4. The status of GALLEX

    SciTech Connect

    Wink, R.; The GALLEX Collaboration

    1991-12-31

    We describe the status of G A L L E X solar neutrino experiment until the end of June 1991. Since June 1990 31 desorptions with the full equipment have been done. The results of the first 27 desorptions are presented. We also describe our low level proportional counters including the counting system.

  5. The status of GALLEX

    SciTech Connect

    Wink, R. )

    1991-01-01

    We describe the status of G A L L E X solar neutrino experiment until the end of June 1991. Since June 1990 31 desorptions with the full equipment have been done. The results of the first 27 desorptions are presented. We also describe our low level proportional counters including the counting system.

  6. Development of grout formulations for 106-AN waste: Mixture-experiment results and analysis. Volume 2, Data presentation

    SciTech Connect

    Spence, R.D.; McDaniel, E.W.; Anderson, C.M.; Lokken, R.O.; Piepel, G.F.

    1993-09-01

    Twenty potential ingredients were identified for use in developing a 106-AN grout formulation, and 18 were subsequently obtained and tested. Four ingredients: Type II-LA (moderate heat of hydration) Portland cement, Class F fly ash, attapulgite 150 drilling clay, and ground air-cooled blast-furnace slag (GABFS) -- were selected for developing the 106-AN grout formulations. A mixture experiment was designed and conducted around the following formulation: 2.5 lb of cement per gallon, 1.2 lb of fly ash per gallon, 0.8 lb of attapulgite per gallon, and 3.5 lb of GABFS per gallon. Reduced empirical models were generated from the results of the mixture experiment. These models were used to recommend several grout formulations for 106-AN. Westinghouse Hanford Company selected one of these formulations to be verified for use with 106-AN and a backup formulation in case problems arise with the first choice. This report presents the mixture-experimental results and leach data.

  7. AOCM program 1992 to 1993 status report: Basilisk subscale laser experiments

    SciTech Connect

    Hermann, M.; Norton, M.; Honig, J.; Hackel, L.

    1994-01-13

    This report summarizes the work performed by the Advanced Optical Counter Measures (AOCM) program from January 1992 to February 1993, funded by the US DOD and administered by the US Army`s Night Vision and Electro-optics Directorate (NVEOD). The AOCM program objective was the development of an advanced anti-sensor weapon system, the Basilisk laser. Basilisk is a high power, white light laser. Its compact size permits deployment on a variety of platforms, including the Bradley Fighting vehicle, where Basilisk would augment the Bradley`s conventional weapon systems. The effectiveness of Basilisk was recently demonstrated in a series of battlefield simulations, CTAS 2.5, where its Mission Defeat Score was eight times higher than lower energy anti-sensor laser systems. In November 1991, a five phase strategy was proposed to develop the Basilisk white light laser system. This report documents the experimental activities performed by the AOCM program and describes several major experimental milestones we achieved during the first year of funding. The focus of this report is on a series of subscale experiments to demonstrate key laser physics and engineering technologies.

  8. Current Status of MPPE (Mercury Plasma Particle Experiment) on BepiColombo/MMO

    NASA Astrophysics Data System (ADS)

    Saito, Yoshifumi; Hirahara, Masafumi; Barabash, Stas; Delcourt, Dominique; André, Nicolas; Takashima, Takeshi; Asamura, Kazushi

    2015-04-01

    Mercury's plasma/particle environment has gradually become clear thanks to the new observations made by MESSENGER spacecraft orbiting around Mercury. However, it is also true that many questions will be left unsolved. In order to elucidate the detailed plasma structure and dynamics around Mercury, an orbiter BepiColombo MMO (Mercury Magnetospheric Orbiter) is going to be launched in 2016 as a joint mission between ESA and ISAS/JAXA. Mercury Plasma/Particle Experiment (MPPE) is a comprehensive instrument package for plasma, high-energy particle and energetic neutral atom measurements. It consists of 7 sensors: two Mercury Electron Analyzers (MEA1 and MEA2), Mercury Ion Analyzer (MIA), Mass Spectrum Analyzer (MSA), High Energy Particle instrument for electron (HEP-ele), High Energy Particle instrument for ion (HEP-ion), and Energetic Neutrals Analyzer (ENA). Currently, the MPPE sensors are on the MMO spacecraft under system integration test at ISAS/JAXA (Institute of Space and Astronautical Science / Japan Aerospace Exploration Agency). Evaluation of the sensor calibration data and the final check of the onboard processing software are being made in order to realize the flawless future plasma/particle observations around Mercury.

  9. Subtask 12H2: Status of the dynamic helium charging experiment

    SciTech Connect

    Tsai, H.; Strain, R.V.; Chung, H.M.; Smith, D.L.

    1995-03-01

    The objective of the dynamic helium charging experiment (DHCE) is to investigate the effects of concurrent helium production and fast-neutron irradiation on the physical and mechanical properties of vanadium-based alloys for fusion blanket applications. A major task in this reporting period was to disassemble the tritium-bearing DHCE capsules to retrieve irradiated specimens for examination and testing. Seven DHCE capsules containing vanadium-alloy specimens were irradiated in the MOTA-2B vehicle in FFTF to {approx}20-29 dpa. In this and the previous reporting periods, equipment and procedures were developed at Argonne National Laboratory-East to disassemble these capsules. Six of the seven capsules have been disassembled. (The seventh capsule was processed in April 1994, immediately following this reporting period.) Effluence of tritium into the cell exhaust was <2% of the total inventory. No contamination incidents occurred during the DHCE disassembly work. Initial testing of the retrieved specimens is under way. 3 refs., 1 fig., 1 tab.

  10. The current status of the GRAPES-3 extensive air shower experiment

    NASA Astrophysics Data System (ADS)

    Gupta, S. K.; Antia, H. M.; Dugad, S. R.; Goswami, U. D.; Hayashi, Y.; Iyer, A.; Ito, N.; Jagadeesan, P.; Jain, A.; Karthikeyan, S.; Kawakami, S.; Minamino, M.; Mohanty, P. K.; Morris, S. D.; Nayak, P. K.; Nonaka, T.; Oshima, A.; Rao, B. S.; Ravindran, K. C.; Tanaka, H.; Tonwar, S. C.; Grapes-3 Collaboration

    2009-12-01

    The GRAPES-3 is a dense extensive air shower array operating with ˜400 scintillator detectors and it also contains a 560 m 2 tracking muon detector ( E>1 GeV), at Ooty in India. 25% of scintillator detectors are instrumented with two fast photomultiplier tubes (PMTs) for extending the dynamic range to ˜5×10 particles m -2 . The scintillators, signal processing electronics and data recording systems were fabricated in-house to cut costs and optimize performance. The muon multiplicity distribution of the EAS is used to probe the composition of primary cosmic rays below the 'knee', with an overlap with direct measurements. Search for multi-TeV γ-rays from point sources is done with the aid of the muon detector. A good angular resolution of 0.7° at 30 TeV, is measured from the shadow of the Moon on the isotropic flux of cosmic rays. A sensitive limit on the diffuse flux of 100 TeV γ-rays is placed by using muon detector to filter the charged cosmic ray background. A tracking muon detector allows sensitive measurements on coronal mass ejections and solar flares through Forbush decrease events. We have major expansion plans to enhance the sensitivity of the GRAPES-3 experiment in the areas listed above.

  11. The COBRA experimentStatus and prospects on the search of neutrinoless double beta-decay

    SciTech Connect

    Zatschler, S.

    2015-10-28

    The Cadmium-Zinc-Telluride 0-ν Double Beta Research Apparatus (COBRA) [1] is a next-generation experiment searching for the existence of neutrinoless double beta-decay (0νββ-decay). The observation of 0νββ-decay would be an unambiguous sign for physics beyond the Standard Model such as lepton number violating processes and would prove the Majorana character of neutrinos. Furthermore, the study of 0νββ-decay could probe the absolute neutrino mass and allows for the identification of the neutrino mass hierarchy realized in nature assuming light Majorana neutrino exchange. Currently a demonstrator setup at the underground facility LNGS (Italy) built of 4×4×4 coplanar grid (CPG) detectors collects high quality low background physics data with FADC pulse shape sampling. The detectors are made of natural abundant CdZnTe (CZT), which is a commercially available room temperature semiconductor. It contains several double beta isotopes, the most promising of which is {sup 116}Cd with a Q-value of 2813.5 keV – which is well above the highest naturally occurring prominent γ-lines.

  12. Gonadal status and reproductive function following treatment for Hodgkin's disease in childhood: The Stanford experience

    SciTech Connect

    Ortin, T.T.; Shostak, C.A.; Donaldson, S.S. )

    1990-10-01

    To ascertain the impact of therapy on gonadal function and reproductive outcome among children treated for Hodgkin's disease, we reviewed the experience at Stanford University Medical Center during the years 1965-1986. There were 240 children 15 years of age or younger, 92 girls and 148 boys; with median follow-up of 9 years, maximum follow-up was 26 years. Of this cohort, data on gonadal function were available on 20 boys, 5 of whom were considered prepubescent; they had no clinical evidence of sexual maturation and were less than 13 years of age. Evaluation of the boys included testicular biopsy, semen analyses and the ability to procreate. Serum gonadotropin hormone levels (FSH, LH) were studied in 11 boys who also had semen analyses. Sexual maturation was attained in all boys without the need for androgen replacement. Among the eight boys treated with radiation alone, four were able to father a child (3 following 40-45 Gy pelvic radiation dose, 1 without pelvic radiation) from 3-19 years following treatment. Three others who received 30-44 Gy pelvic radiation were oligospermic when tested at 10 to 15 years post-treatment. Semen analyses in 10 of 12 (83%) boys who had been treated with six cycles of MOPP with or without pelvic radiation revealed absolute azoospermia with no evidence of recovery as along as 11 years of follow-up. Following prolonged azoospermia, 2 of the 12 boys (17%) had recovery of fertility, with normalization of sperm count and/or ability to procreate at 12 and 15 years following treatment. There was no correlation with serum gonadotropin levels and sterility. Data on menstrual history, pregnancy and offspring were available in 86 (92%) of the girls. Seventy-five of the 86 girls (87%) have normal menstrual function. However, none of the females who underwent pelvic radiation without prior oophoropexy has maintained ovarian function.

  13. 'We keep her status to ourselves': experiences of stigma and discrimination among HIV-discordant couples in South Africa, Tanzania and Ukraine.

    PubMed

    Rispel, Laetitia C; Cloete, Allanise; Metcalf, Carol A

    2015-01-01

    In HIV-discordant relationships, the HIV-negative partner also carries the burden of a stigmatised disease. For this reason, couples often hide their HIV-discordant status from family, friends and community members. This perpetuates the silence around HIV-discordant relationships and impacts on targeted HIV prevention, treatment and counselling efforts. This article reports on experiences of stigma and discrimination among HIV-discordant couples in South Africa, Tanzania and Ukraine. During 2008, HIV-discordant couples who had been in a relationship for at least one year were recruited purposively through health-care providers and civil society organisations in the three countries. Participants completed a brief self-administered questionnaire, while semi-structured interviews were conducted with each partner separately and with both partners together. Interviews were analysed using thematic content analysis. Fifty-one couples were recruited: 26 from South Africa, 10 from Tanzania, and 15 from Ukraine. Although most participants had disclosed their HIV status to someone other than their partner, few were living openly with HIV discordance. Experiences of stigma were common and included being subjected to gossip, rumours and name-calling, and HIV-negative partners being labelled as HIV-positive. Perpetrators of discrimination included family members and health workers. Stigma and discrimination present unique and complex challenges to couples in HIV sero-discordant relationships in these three diverse countries. Addressing stigmatisation of HIV-discordant couples requires a holistic human rights approach and specific programme efforts to address discrimination in the health system.

  14. ‘We keep her status to ourselves’: Experiences of stigma and discrimination among HIV-discordant couples in South Africa, Tanzania and Ukraine

    PubMed Central

    Rispel, Laetitia C.; Cloete, Allanise; Metcalf, Carol A.

    2015-01-01

    Abstract In HIV-discordant relationships, the HIV-negative partner also carries the burden of a stigmatised disease. For this reason, couples often hide their HIV-discordant status from family, friends and community members. This perpetuates the silence around HIV-discordant relationships and impacts on targeted HIV prevention, treatment and counselling efforts. This article reports on experiences of stigma and discrimination among HIV-discordant couples in South Africa, Tanzania and Ukraine. During 2008, HIV-discordant couples who had been in a relationship for at least one year were recruited purposively through health-care providers and civil society organisations in the three countries. Participants completed a brief self-administered questionnaire, while semi-structured interviews were conducted with each partner separately and with both partners together. Interviews were analysed using thematic content analysis. Fifty-one couples were recruited: 26 from South Africa, 10 from Tanzania, and 15 from Ukraine. Although most participants had disclosed their HIV status to someone other than their partner, few were living openly with HIV discordance. Experiences of stigma were common and included being subjected to gossip, rumours and name-calling, and HIV-negative partners being labelled as HIV-positive. Perpetrators of discrimination included family members and health workers. Stigma and discrimination present unique and complex challenges to couples in HIV sero-discordant relationships in these three diverse countries. Addressing stigmatisation of HIV-discordant couples requires a holistic human rights approach and specific programme efforts to address discrimination in the health system. PMID:25778765

  15. Gender Differences in the Occupational Status of Undocumented Immigrants in the United States: Experience Before and After Legalization.

    ERIC Educational Resources Information Center

    Powers, Mary G.; Seltzer, William; Shi, Jing

    1998-01-01

    Examines the incorporation of undocumented immigrants before and after application for legal status under the Immigration Reform and Control Act of 1986 (IRCA). Provides descriptive analysis of gender differences in labor-force participation and occupational status and multivariate analysis of variables in occupational status between genders.…

  16. High Energy Neutrinos from the Cold: Status and Prospects of the IceCube Experiment

    SciTech Connect

    IceCube Collaboration; Portello-Roucelle, Cecile; Collaboration, IceCube

    2008-02-29

    The primary motivation for building neutrino telescopes is to open the road for neutrino astronomy, and to offer another observational window for the study of cosmic ray origins. Other physics topics, such as the search for WIMPs, can also be developed with neutrino telescope. As of March 2008, the IceCube detector, with half of its strings deployed, is the world largest neutrino telescope taking data to date and it will reach its completion in 2011. Data taken with the growing detector are being analyzed. The results of some of these works are summarized here. AMANDA has been successfully integrated into IceCube data acquisition system and continues to accumulate data. Results obtained using only AMANDA data taken between the years 2000 and 2006 are also presented. The future of IceCube and the extensions in both low and high energy regions will finally be discussed in the last section.

  17. Does trophic status enhance or reduce the thermal tolerance of scleractinian corals? A review, experiment and conceptual framework.

    PubMed

    Fabricius, Katharina E; Cséke, Szilvia; Humphrey, Craig; De'ath, Glenn

    2013-01-01

    Global warming, and nutrient and sediment runoff from coastal development, both exert increasing pressures on coastal coral reefs. The objective of this study was to resolve the question of whether coastal eutrophication may protect corals from thermal stress by improving their nutritional status, or rather diminish their thermal tolerance through the synergy of dual stressors. A review of previous studies on the topic of combined trophic status and heat exposure on the thermal tolerance of corals reveals a broad range of outcomes, including synergistic, additive and antagonistic effects. We conducted a 90-day long experiment exposing corals to realistic levels of elevated nutrients and sediments, and heat stress. Colonies of two common scleractinian corals (Acropora millepora and Montipora tuberculosa) were kept in coastal seawater, or coastal seawater that was further organically and nutrient enriched (OE), and/or enriched with nitrate. Batches of OE were created daily, facilitating nutrient uptake, plankton succession and organic enrichment as observed in coastal waters. After 10 days of acclimation, 67% of the colonies had their temperature gradually increased from 27° to 31.2°C. After 3-7 weeks of heat stress, colonies of both species had significantly greater reductions in fluorescence yields and lower survival in OE than without addition of OE. Furthermore, photophysiological recovery was incomplete 31-38 days after ending the heat stress only in the OE treatments. Nitrate alone had no measurable effect on survival, bleaching and recovery in either species. Skeletal growth rates were reduced by 45% in heat-stressed A. millepora and by 24% in OE-exposed M. tuberculosa. We propose a conceptual trophic framework that resolves some of the apparently contradictory outcomes revealed by the review. Our study shows that management actions to reduce coastal eutrophication can improve the resistance and resilience of vulnerable coastal coral reefs to warming

  18. The High Lava Plains Broadband Seismic Experiment: Objectives, Status and Preliminary Results

    NASA Astrophysics Data System (ADS)

    James, D. E.; Fouch, M.; Eager, K.; Nair, S.; Roth, J.; Warren, L.; Beghein, C.; West, J.; Carlson, R.; Johnson, J.; Golden, S.

    2006-12-01

    The High Lava Plains (HLP) Project is a multi-disciplinary program to study the structure and formation of the high lava plains volcanic lineament, the most prominent feature of the actively evolving continental lithosphere in central and eastern Oregon. This region in the Pacific Northwest represents one of the most accessible, yet least understood, examples worldwide of the tectonomagmatic consequences of plate margin restructuring on the development of continental lithosphere. The confusing and complex tectonomagmatic evolution there has been variously ascribed to the Yellowstone plume, back-arc subduction processes, Basin and Range extension, or asthenospheric inflow along the migrating edge of the descending Juan de Fuca (formerly Farallon) plate. Various aspects of each of these processes are either mutually exclusive or apparently inconsistent with observations, but the seismic data that could resolve key questions of tectonomagmatic development have been conspicuously absent. The HLP Seismic Experiment is organized around multi-level broadband and active source seismic studies of the crust and mantle beneath young continent now largely blanketed with late Cenozoic volcanic rocks. The dense broadband array, when fully configured, will consist of about 170 stations in a region ~ 500 x 350 km. The high station density will make it possible to resolve fine-scale structures in the crust and mantle beneath the extensive region of post-17 Ma volcanism and at its margins with Proterozoic North America, the Northern Great Basin, and Cascadia with detail well beyond the capabilities of the more sparse EarthScope USArray Transportable Array. Synthetic resolution tests of tomographic images demonstrate sharply contrasting capabilities between the two arrays, particularly for imaging localized low-velocity features in the uppermost mantle. While the full HLP array is not scheduled for deployment until late spring, 2007, the installation of a skeletal array began in

  19. Status of the NGNP Graphite Creep Experiments AGC-1 and AGC-2 Irradiated in the Advanced Test Reactor

    SciTech Connect

    Blaine Grover

    2012-10-01

    The United States Department of Energy’s Next Generation Nuclear Plant (NGNP) Program will be irradiating six nuclear graphite creep experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The graphite experiments will be irradiated over the next six to eight years to support development of a graphite irradiation performance data base on the new nuclear grade graphites now available for use in high temperature gas reactors. The goals of the irradiation experiments are to obtain irradiation performance data, including irradiation creep, at different temperatures and loading conditions to support design of the Next Generation Nuclear Plant (NGNP) Very High Temperature Gas Reactor, as well as other future gas reactors. The experiments will each consist of a single capsule that will contain six peripheral stacks of graphite specimens, with half of the graphite specimens in each stack under a compressive load, while the other half of the specimens will not be subjected to a compressive load during irradiation. The six peripheral stacks will have different compressive loads applied to the top half of each pair of specimen stacks, while a seventh stack will not have a compressive load. The specimens will be irradiated in an inert sweep gas atmosphere with on-line temperature and compressive load monitoring and control. There will also be sampling the sweep gas effluent to determine if any oxidation or off-gassing of the specimens occurs during irradiation of the experiment. The first experiment, AGC-1, started its irradiation in September 2009, and the irradiation was completed in January 2011. The second experiment, AGC-2, started its irradiation in April 2011 and completed its irradiation in May 2012. This paper will briefly discuss the design of the experiment and control systems, and then present the irradiation results for each experiment to date.

  20. [Influence of smoking intoxicants on dental status. Literature search and own experience].

    PubMed

    Hilt, Aleksandra; Rybarczyk-Townsend, Ewa

    2014-01-01

    Amphetamines are phenylpropane derivatives belonging to the group of psychostimulating substances. Within the space of years, on account of their stimulating properties, they were used as treatment substances, e.g. in Attention deficit hyperactivity disorder (ADHD ), in obesity as slimming substances, in preventing of paroxysmal drowsiness, as dilating bronchi substances, used as some dope in sports and willingly abused among drug addicts because of long lasting exciting euphoria after use. Methamphetamine, an amphetamine derivative, has even stronger and longer lasting effect. The study presents characteristics of a popular, among teenagers, addictive substance - amphetamine and its derivative- methamphetamine and its influence on teeth after using it in a smoking form. The condition of oral cavity of a 17-year-old patient, who has been using methamphetamine in a smoking form for about 3 years, was described. In the oral cavity of the patient numerous and extensive caries lesions were noticed, placed mainly in the labial cervical area of teeth as well as, a considerable damage of teeth's crowns and teeth loss. The patient needed complex dental treatment: conservative, endodontic, surgical and prosthetic. The use of intoxicating substances, derivatives of amphetamine in form of regular smoking caused a considerable damage of tooth tissues, leading to their loss.

  1. Ophthalmic surgical training in Karnataka and Southern India: Present status and future interests from a survey of final-year residents

    PubMed Central

    Ajay, K; Krishnaprasad, R; Divya, D S

    2015-01-01

    Settings and Design: This study documents a survey of final-year ophthalmology postgraduates on the subject of their surgical training and their future plans after residency. Purpose: This survey aimed to answer the question, What is the present status of surgical training in ophthalmic training centers? by obtaining information from students about (1) various methods used in surgical training (2) numbers and types of surgeries performed by them in the training centers (3) their plans after residency. Materials and Methods: A questionnaire containing 21 questions was distributed to 155 students attending an intensive 4-day teaching program. The questions related to orientation training, wet lab training, facilities for training, free surgical camps and detailed information about numbers and types of surgeries observed and performed. Completed questionnaires were collected, and responses analyzed. Results: One hundred and seven completed responses were analyzed. The majority had not received formal orientation training. More than half had undergone wet lab training. Most residents performed their first ophthalmic surgery during the 1st year of residency and went to the operation theatre multiple times a week. Most of the students planned to undergo further training after residency. More than half of the students found their surgical training to be fair or satisfactory. Conclusions: The number and frequency of ophthalmic surgeries done by residents appear satisfactory, but further efforts from trainers on enhancing the quality and range of surgical training would benefit students and improve their satisfaction. PMID:26044468

  2. New-onset refractory status epilepticus in an adult with an atypical presentation of cat-scratch disease: successful treatment with high-dose corticosteroids.

    PubMed

    Laswell, Emily M; Chambers, Kasandra D; Whitsel, Danielle R; Poudel, Kiran

    2015-06-01

    New-onset refractory status epilepticus (NORSE) is defined as a sudden onset of refractory status epilepticus in patients who do not have a history of epilepsy. It is a neurologic emergency, and determining the underlying etiology is an important factor for effectively managing and predicting the prognosis of NORSE. We describe the case of a 28-year-old woman who was hospitalized with NORSE secondary to an unknown etiology. She did not respond to traditional anticonvulsant therapy, including benzodiazepines, fosphenytoin, propofol, and levetiracetam. The patient was placed on continuous electroencephalography (EEG) monitoring and was treated further with multiple antiepileptics, which were titrated aggressively based on EEG readings and therapeutic drug levels; despite this treatment, EEG monitoring revealed continued seizures. Thus, high-dose corticosteroids were started for seizure control. Her workup included computed tomography and magnetic resonance imaging of the head, a lumbar puncture, toxicology screening, and extensive testing for multiple infectious and inflammatory etiologies. The patient's history revealed recent exposure to a new cat. Serologic results were positive for Bartonella henselae, and she was diagnosed with cat-scratch disease (CSD). She did not have the typical presentation of symptoms of lymphadenopathy, however, which is common in CSD. Doxycycline 100 mg and rifampin 300 mg twice daily were added to the patient's anticonvulsant and corticosteroid therapy. She was hospitalized for a total of 26 days and discharged with only minor neurologic impairment (short-term memory deficits and minor cognitive problems). The patient was discharged receiving antiepileptics, antibiotics, and a corticosteroid taper. To our knowledge, this is the first clinically known case of NORSE secondary to CSD without typical CSD symptoms in the adult population. The patient failed to respond to traditional anticonvulsant therapy alone. With the addition of high

  3. The past, present, and future of National Aeronautics and Space Administration spaceflight diet in support of microgravity rodent experiments.

    PubMed

    Sun, Gwo-Shing; Tou, Janet C; Yu, Diane; Girten, Beverly E; Cohen, Jacob

    2014-02-01

    Rodents have been the most frequently flown animal model used to study physiological responses to the space environment. In support of future of space exploration, the National Aeronautics and Space Administration (NASA) envisions an animal research program focused on rodents. Therefore, the development of a rodent diet that is suitable for the spaceflight environment including long duration spaceflight is a high priority. Recognizing the importance of nutrition in affecting spaceflight physiological responses and ensuring reliable biomedical and biological science return, NASA developed the nutrient-upgraded rodent food bar (NuRFB) as a standard diet for rodent spaceflight. Depending on future animal habitat hardware and planned spaceflight experiments, modification of the NuRFB or development of a new diet formulation may be needed, particularly for long term spaceflights. Research in this area consists primarily of internal technical reports that are not readily accessible. Therefore, the aims of this contribution are to provide a brief history of the development of rodent spaceflight diets, to review the present diet used in rodent spaceflight studies, and to discuss some of the challenges and potential solutions for diets to be used in future long-term rodent spaceflight studies. PMID:24012282

  4. The past, present, and future of National Aeronautics and Space Administration spaceflight diet in support of microgravity rodent experiments.

    PubMed

    Sun, Gwo-Shing; Tou, Janet C; Yu, Diane; Girten, Beverly E; Cohen, Jacob

    2014-02-01

    Rodents have been the most frequently flown animal model used to study physiological responses to the space environment. In support of future of space exploration, the National Aeronautics and Space Administration (NASA) envisions an animal research program focused on rodents. Therefore, the development of a rodent diet that is suitable for the spaceflight environment including long duration spaceflight is a high priority. Recognizing the importance of nutrition in affecting spaceflight physiological responses and ensuring reliable biomedical and biological science return, NASA developed the nutrient-upgraded rodent food bar (NuRFB) as a standard diet for rodent spaceflight. Depending on future animal habitat hardware and planned spaceflight experiments, modification of the NuRFB or development of a new diet formulation may be needed, particularly for long term spaceflights. Research in this area consists primarily of internal technical reports that are not readily accessible. Therefore, the aims of this contribution are to provide a brief history of the development of rodent spaceflight diets, to review the present diet used in rodent spaceflight studies, and to discuss some of the challenges and potential solutions for diets to be used in future long-term rodent spaceflight studies.

  5. Storage Ring EDM Experiments

    NASA Astrophysics Data System (ADS)

    Semertzidis, Yannis K.

    2016-04-01

    Dedicated storage ring electric dipole moment (EDM) methods show great promise advancing the sensitivity level by a couple orders of magnitude over currently planned hadronic EDM experiments. We describe the present status and recent updates of the field.

  6. Status of core-debris coolability experiments with real and simulant materials at Argonne National Laboratory. [LMFBR

    SciTech Connect

    Pedersen, D.R.; Sowa, E.; Gabor, J.D.; Jones, S.; Baker, L. Jr.; Epstein, M.

    1982-01-01

    The two major areas of interest in the debris-bed coolability experiments at ANL are: (1) development of a data base against which existing debris bed coolability models can be compared and to provide insight into the development of future models and (2) investigation of the possible mechanisms which prevent channel formation in a debris bed with real material experiments. The mechanism under consideration are: (a) subcooling of overlying sodium, (b) UO/sub 2+x/ reduction by sodium, (c) failure of the sodium to wet the fuel and (d) concrete reaction products. Sandia has proposed that subcooling of the overlying sodium is sufficient to prevent channel formation and was the cause of the observed reduction in coolability with increasing subcooling. The results of experiments on each of the mechanisms are to be presented.

  7. White and Black Careers during the First Ten Years of Work Experience: A Simultaneous Consideration of Occupational Status and Income Changes.

    ERIC Educational Resources Information Center

    Coleman, James S.; And Others

    This analysis examined the major differences in patterns of occupational achievement of blacks and whites during the first decade of labor force experience after last leaving full-time schooling. In large part, the analysis was designed to examine differences in the processes underlying the attainment of two dimensions of achievement, status, and…

  8. Status of tokamak experiments

    SciTech Connect

    Wolf, G.H.

    1996-03-01

    Plasma-wall interaction, heat removal and ash exhaust have emerged as the dominant problems still to be solved in order to achieve ignition and - even more difficult - to maintain a state of self-sustained thermo-nuclear burn. This is of particular delicacy, since those operational regimes which yield the best energy confinement correspond to an even better particle confinement and confinement of impurities, which then tend to accumulate in the plasma core and to result in disruption or degradation of the tokamak discharge. Therefore, plasma-wall interaction, heat removal and particle exhaust will determine not only the structure and configuration of the plasma edge region, of the wall system and of the materials facing the plasma, but also the final choice of useful confinement regimes. Moreover, the potential effect of powerful {alpha}-particle heating on plasma stability and confinement has to be kept below critical values. For the latter requirement, a final answer can only be obtained in an ITER-type device where ignition and burn will become accessible. 72 refs., 12 figs.

  9. Perceptions and Experiences about Self-Disclosure of HIV Status among Adolescents with Perinatal Acquired HIV in Poor-Resourced Communities in South Africa

    PubMed Central

    Mokgatle, Mathildah

    2016-01-01

    Background. There is limited research on the disclosure experiences of adolescents with perinatal acquired HIV (PAH). The study explores how adolescents with PAH experience living with HIV and examined their perceptions and experiences regarding disclosure and onward self-disclosure to friends and sexual partners. Methods. Thematic analysis was used to analyze in-depth interviews conducted with 37 adolescents. Findings. Adolescents received disclosure about their status at mean age of 12 years. They perceived disclosure as necessary and appreciated the truthful communication they received. Adolescents have learned to accept and live with HIV, and they desired to be healthy and normal like other people. After receiving disclosure, they found their treatment meaningful, and they adhered to medication. However, they also expressed a strong message that their HIV status was truly their secret and that self-disclosure to others will take the feeling of being normal away from them because they will be treated differently. Conclusion. Adolescents maintained secrecy in order to be accepted by their peers but also to protect themselves from stigma and isolation. Given that adolescents want to be informed of their HIV status but desire controlling self-disclosure of their HIV status, these should form the basis for development of disclosure interventions. PMID:27672451

  10. Perceptions and Experiences about Self-Disclosure of HIV Status among Adolescents with Perinatal Acquired HIV in Poor-Resourced Communities in South Africa

    PubMed Central

    Mokgatle, Mathildah

    2016-01-01

    Background. There is limited research on the disclosure experiences of adolescents with perinatal acquired HIV (PAH). The study explores how adolescents with PAH experience living with HIV and examined their perceptions and experiences regarding disclosure and onward self-disclosure to friends and sexual partners. Methods. Thematic analysis was used to analyze in-depth interviews conducted with 37 adolescents. Findings. Adolescents received disclosure about their status at mean age of 12 years. They perceived disclosure as necessary and appreciated the truthful communication they received. Adolescents have learned to accept and live with HIV, and they desired to be healthy and normal like other people. After receiving disclosure, they found their treatment meaningful, and they adhered to medication. However, they also expressed a strong message that their HIV status was truly their secret and that self-disclosure to others will take the feeling of being normal away from them because they will be treated differently. Conclusion. Adolescents maintained secrecy in order to be accepted by their peers but also to protect themselves from stigma and isolation. Given that adolescents want to be informed of their HIV status but desire controlling self-disclosure of their HIV status, these should form the basis for development of disclosure interventions.

  11. Perceptions and Experiences about Self-Disclosure of HIV Status among Adolescents with Perinatal Acquired HIV in Poor-Resourced Communities in South Africa.

    PubMed

    Madiba, Sphiwe; Mokgatle, Mathildah

    2016-01-01

    Background. There is limited research on the disclosure experiences of adolescents with perinatal acquired HIV (PAH). The study explores how adolescents with PAH experience living with HIV and examined their perceptions and experiences regarding disclosure and onward self-disclosure to friends and sexual partners. Methods. Thematic analysis was used to analyze in-depth interviews conducted with 37 adolescents. Findings. Adolescents received disclosure about their status at mean age of 12 years. They perceived disclosure as necessary and appreciated the truthful communication they received. Adolescents have learned to accept and live with HIV, and they desired to be healthy and normal like other people. After receiving disclosure, they found their treatment meaningful, and they adhered to medication. However, they also expressed a strong message that their HIV status was truly their secret and that self-disclosure to others will take the feeling of being normal away from them because they will be treated differently. Conclusion. Adolescents maintained secrecy in order to be accepted by their peers but also to protect themselves from stigma and isolation. Given that adolescents want to be informed of their HIV status but desire controlling self-disclosure of their HIV status, these should form the basis for development of disclosure interventions. PMID:27672451

  12. Overview Presentation

    NASA Technical Reports Server (NTRS)

    Lytle, John

    2001-01-01

    This report provides an overview presentation of the 2000 NPSS (Numerical Propulsion System Simulation) Review and Planning Meeting. Topics include: 1) a background of the program; 2) 1999 Industry Feedback; 3) FY00 Status, including resource distribution and major accomplishments; 4) FY01 Major Milestones; and 5) Future direction for the program. Specifically, simulation environment/production software and NPSS CORBA Security Development are discussed.

  13. Present Status of Drawing and Art in the Elementary and Secondary Schools of the United States. Bulletin, 1914, No. 13. Whole Number 586

    ERIC Educational Resources Information Center

    Farnum, Royal Bailey

    1914-01-01

    There is a general demand for information in regard to the condition of drawing and art in the elementary and secondary schools of this and other countries. In partial response to this demand Mr. Royal Bailey Farnum, specialist in drawing and handwork in the New York State Education Department, has prepared this manuscript showing the status of…

  14. National and Global: A History of Scholars' Experiences with Research at the University of Dar Es Salaam, Tanzania (1961-Present)

    ERIC Educational Resources Information Center

    Jamison, Amy J.

    2010-01-01

    In this dissertation, I draw on research carried out at the University of Dar es Salaam (UDSM), Tanzania in 2008 to examine Tanzanian academics' experience with research throughout the history of this institution. This dissertation is designed as an historical case study and investigates how economic and political changes in Tanzania's…

  15. Student Perceptions of Value Added in an Active Learning Experience: Producing, Reviewing and Evaluating a Sales Team Video Presentation

    ERIC Educational Resources Information Center

    Corbett, James J.; Kezim, Boualem; Stewart, James

    2010-01-01

    This study investigates the effectiveness of a video team-based activity as a learning experience in a sales management course. Students perceived this learning activity approach as a beneficial and effective instructional technique. The benefits of making a video in a marketing course reinforce the understanding and the use of the sales process…

  16. Cross Sections for Neutron-induced Reactions on Actinide Targets Extracted from Surrogate Experiments: A Status Report

    SciTech Connect

    Escher, J E; Burke, J T; Dietrich, F S; Lesher, S R; Scielzo, N D; Thompson, I J; Younes, W

    2009-10-01

    The Surrogate nuclear reactions method, an indirect approach for determining cross sections for compound-nuclear reactions involving difficult-to-measure targets, is reviewed. Focusing on cross sections for neutron-induced reactions on actinides, we review the successes of past and present applications of the method and assess its uncertainties and limitations. The approximations used in the analyses of most experiments work reasonably well for (n,f) cross sections for neutron energies above 1-2 MeV, but lead to discrepancies for low-energy (n,f) reactions, as well as for (n,{gamma}) applications. Correcting for some of the effects neglected in the approximate analyses leads to improved (n,f) results. We outline steps that will further improve the accuracy and reliability of the Surrogate method and extend its applicability to reactions that cannot be approached with the present implementation of the method.

  17. The implementation of game in a 20-day head-down tilting bed rest experiment upon mood status and neurotic levels of rest subjects.

    PubMed

    Ishizaki, Yuko; Fukuoka, Hideoki; Ishizaki, Tatsuro; Tanaka, Hidetaka; Ishitobi, Hiromi

    2004-12-01

    This study evaluated the effect of the implementation of game on mental health among participants in a bedrest (BR) experiment. Subjects were 12 healthy males aged 20-26, who participated in a 20-day 6-degrees head-down tilting BR experiment. The participants were asked to complete psychometrical questionnaires before, during, and after the experiment. We entrusted the participants to manage their leisure time and they intended a game in which all of them could take part over the experiment period. The general conversation and light-hearted mood among the subjects continued during the experimental period. Longitudinal data analysis showed that levels of neurosis and mood status did not deteriorate during the experiment, while our previous experiments, which were performed under the same protocol as this study except for the implementation of the game showed a distinct deterioration in psychosocial status. We consider that the implementation of game autonomously contributes to the positive effects on the mental health among the participants.

  18. The implementation of game in a 20-day head-down tilting bed rest experiment upon mood status and neurotic levels of rest subjects

    NASA Astrophysics Data System (ADS)

    Ishizaki, Yuko; Fukuoka, Hideoki; Ishizaki, Tatsuro; Tanaka, Hidetaka; Ishitobi, Hiromi

    2004-12-01

    This study evaluated the effect of the implementation of game on mental health among participants in a bed rest (BR) experiment. Subjects were 12 healthy males aged 20-26, who participated in a 20-day 6-degrees head-down tilting BR experiment. The participants were asked to complete psychometrical questionnaires before, during, and after the experiment. We entrusted the participants to manage their leisure time and they intended a game in which all of them could take part over the experiment period. The general conversation and light-hearted mood among the subjects continued during the experimental period. Longitudinal data analysis showed that levels of neurosis and mood status did not deteriorate during the experiment, while our previous experiments, which were performed under the same protocol as this study except for the implementation of the game showed a distinct deterioration in psychosocial status. We consider that the implementation of game autonomously contributes to the positive effects on the mental health among the participants.

  19. Testimony on the Economic Status of Hispanic Children and Families. Presented before the Select Committee on Children, Youth, and Families, U.S. House of Representatives, September 25, 1989.

    ERIC Educational Resources Information Center

    Quiroz, Julia Teresa

    This document presents testimony delivered before the House Select Committee on Children, Youth, and Families on the economic status of Hispanic children and families in the United States. The speaker, a senior policy analyst at the National Council of La Raza, focuses on the strengths of Hispanic families, the economic challenges they face, and…

  20. International experiences in assessing vitamin A status and applying the vitamin A-labeled isotope dilution method.

    PubMed

    Lopez-Teros, Veronica; Chileshe, Justin; Idohou-Dossou, Nicole; Fajarwati, Tetra; Medoua Nama, Gabriel; Newton, Sam; Vinod Kumar, Malavika; Wang, Zhixu; Wasantwisut, Emorn; Hunt, Janet R

    2014-01-01

    Inadequate vitamin A (VA) nutrition continues to be a major problem worldwide, and many interventions being implemented to improve VA status in various populations need to be evaluated. The interpretation of results after an intervention depends greatly on the method selected to assess VA status. To evaluate the effect of an intervention on VA status, researchers in Cameroon, India, Indonesia, Mexico, Senegal and Zambia have used serum retinol as an indicator, and have not always found improvement in response to supplementation. One problem is that homeostatic control of serum retinol may mask positive effects of treatment in that changes in concentration are observed only when status is either moderately to severely depleted or excessive. Because VA is stored mainly in the liver, measurements of hepatic VA stores are the “gold standard” for assessing VA status. Dose response tests such as the relative dose response (RDR) and the modified relative dose response (MRDR), allow a qualitative assessment of VA liver stores. On the other hand, the use of the vitamin A-labeled isotope dilution (VALID) technique, (using 13C or 2H-labeled retinyl acetate) serves as an indirect method to quantitatively estimate total body and liver VA stores. Countries including Cameroon, China, Ghana, Mexico, Thailand and Zambia are now applying the VALID method to sensitively assess changes in VA status during interventions, or to estimate a population’s dietary requirement for VA. Transition to the use of more sensitive biochemical indicators of VA status such as the VALID technique is needed to effectively assess interventions in populations where mild to moderate VA deficiency is more prevalent than severe deficiency. PMID:25537105

  1. Status of Electrostatic Accelerometer Development for Gravity Recovery and Climate Experiment Follow-On Mission (GRACE FO)

    NASA Astrophysics Data System (ADS)

    Perrot, Eddy; Boulanger, Damien; Christophe, Bruno; Foulon, Bernard; Liorzou, Françoise; Lebat, Vincent; Huynh, Phuong-Anh

    2015-04-01

    and will be achieved on January 2015. The results of the Engineering Model tests and the status of the Flight Models will be presented.

  2. Outcome of patients presenting with idiopathic facial nerve paralysis (Bell's palsy) in a tertiary centre--a five year experience.

    PubMed

    Tang, I P; Lee, S C; Shashinder, S; Raman, R

    2009-06-01

    This is a retrospective study. The objective of this study is to review the factors influencing the outcome of treatment for the patients presented with idiopathic facial nerve paralysis. The demographic data, clinical presentation and management of 84 patients with idiopathic facial nerve paralysis (Bell's palsy) were collected from the medical record office, reviewed and analyzed from 2000 to 2005. Thirty-four (72.3%) out of 47 patients who were treated with oral prednisolone alone, fully recovered from Bell's palsy meanwhile 36 (97%) out of 37 patients who were treated with combination of oral prednisolone and acyclovir fully recovered. The difference was statistically significant. 42 (93.3%) out of 45 patients who presented within three days to our clinic, fully recovered while 28 (71.8%) out of 39 patients presented later then three days had full recovery from Bell's palsy. The difference was statistically significant. The outcome of full recovery is better with the patients treated with combined acyclovir and prednisolone compared with prednisolone alone. The patients who were treated after three days of clinical presentation, who were more than 50 years of age, who had concurrent chronic medical illness and facial nerve paralysis HB Grade IV to VI during initial presentation have reduced chance of full recovery of facial nerve paralysis.

  3. Status and Early Results from the Axion Dark Matter eXperiment - High Frequency (ADMX-HF)

    NASA Astrophysics Data System (ADS)

    Lewis, Samantha; ADMX-HF Collaboration

    2016-03-01

    The axion was originally proposed as a solution to the Strong-CP problem of the Standard Model. A sufficiently light axion (1 - 1000 μ eV) also represents an excellent cold dark matter candidate. Such axions may be detected by their resonant conversion to photons in a high- Q microwave cavity permeated by a strong magnetic field. Previous experiments have probed the first decade in mass using this method. ADMX-HF was designed and built as an innovation test-bed and a data pathfinder for the second decade in mass range. The experiment, initially configured with a 9-tesla magnet, dilution refrigerator, 2-liter tunable copper cavity, and a Josephson Parametric Amplifier, is now operational with a system noise temperature approximately twice the Standard Quantum Limit. Preliminary data in the 25 μ eV range (on the order of 6 GHz in resonant frequency) will be presented, as well as an overview of ongoing R&D on new cavity and amplifier technologies that will be validated in situ within the next few years. This work was supported by the NSF, under Grants PHY-1067242 and PHY-1306729, the US DOE under Contract DE-AC52-07NA27344, and an award from the Heising-Simons Foundation.

  4. Voice therapy: From the past to the present from a phoniatrician's perspective (Voice of Experience Keynote, PEVOC 2013, Prague).

    PubMed

    Wendler, Jürgen

    2015-07-01

    The roots of voice therapy can be traced back to the professional use of the voice in antiquity. During the Baroque period, aspects of the singers' voice came to the fore, and in the beginning of the twentieth century, physiologic and medical perspectives concentrating on the peripheral areas of phonation were introduced. In parallel, holistic approaches stressed psychological and behavioral conditions. A vast amount of specific methods and strategies has been developed, but so far there has been no clear evidence revealing which of the approaches provides the best efficacy. According to the experience of the author, rather than the method itself, it is the clinician using the methods who makes the difference. The general guide-line for the choice of an appropriate treatment should be the Hippocratic imperative: primum nil nocere--first do no harm.

  5. Voice therapy: From the past to the present from a phoniatrician's perspective (Voice of Experience Keynote, PEVOC 2013, Prague).

    PubMed

    Wendler, Jürgen

    2015-07-01

    The roots of voice therapy can be traced back to the professional use of the voice in antiquity. During the Baroque period, aspects of the singers' voice came to the fore, and in the beginning of the twentieth century, physiologic and medical perspectives concentrating on the peripheral areas of phonation were introduced. In parallel, holistic approaches stressed psychological and behavioral conditions. A vast amount of specific methods and strategies has been developed, but so far there has been no clear evidence revealing which of the approaches provides the best efficacy. According to the experience of the author, rather than the method itself, it is the clinician using the methods who makes the difference. The general guide-line for the choice of an appropriate treatment should be the Hippocratic imperative: primum nil nocere--first do no harm. PMID:24945781

  6. ν generation: Present and future constraints on neutrino masses from global analysis of cosmology and laboratory experiments

    NASA Astrophysics Data System (ADS)

    Gerbino, Martina; Lattanzi, Massimiliano; Melchiorri, Alessandro

    2016-02-01

    We perform a joint analysis of current data from cosmology and laboratory experiments to constrain the neutrino mass parameters in the framework of Bayesian statistics, also accounting for uncertainties in nuclear modeling, relevant for neutrinoless double β decay (0 ν 2 β ) searches. We find that a combination of current oscillation, cosmological, and 0 ν 2 β data constrains mβ β<0.045 eV (0.014 eV experiments, and find that in the case of normal hierarchy, given a total mass of 0.1 eV, and assuming a factor-of-two uncertainty in the modeling of the relevant nuclear matrix elements, it will be possible to measure the total mass itself, the effective Majorana mass and the effective electron mass with an accuracy (at 95% C.L.) of 0.05, 0.015, 0.02 eV, respectively, as well as to be sensitive to one of the Majorana phases. This assumes that neutrinos are Majorana particles and that the mass mechanism gives the dominant contribution to 0 ν 2 β decay. We argue that more precise nuclear modeling will be crucial to improve these sensitivities.

  7. Analysis Status and Recent Results on νμ → νe Oscillations of the Opera Experiment

    NASA Astrophysics Data System (ADS)

    Kitagawa, Nobuko

    2015-03-01

    The OPERA experiment is designed to demonstrate the transition from νμ to ντ in neutrino oscillations by detecting the ντ appearance. During its 5 years run, from 2008 to 2012, 17.97×1019 protons on target were used to produce the νμ beam. In OPERA, νμ → νe oscillations are also searched for. The results presented in this article use the 2008 and 2009 data. Upper limits of 0.44 for sin2(2θ13) in the three flavour oscillation scheme and of 7.2×10-3 for sin2(2θnew) in a non standard oscillation scheme were set at 90% C.L.

  8. A girl with tuberous sclerosis complex presenting with severe epilepsy and electrical status epilepticus during sleep, and with high-functioning autism and mutism.

    PubMed

    Pacheva, Iliyana; Panov, Georgi; Gillberg, Christopher; Neville, Brian

    2014-06-01

    Most patients with tuberous sclerosis complex (TSC) suffer from epilepsy, and many have cognitive and behavioral problems like severe intellectual disability, autism, and hyperactivity. Only rare patients with TSC and autism have a normal intelligence quotient. We report a 13-year-old girl with definite TSC who had early-onset severe epilepsy, autistic behavior, and moderate developmental delay. By school age, however, she had normal intelligence; her intelligence quotient was at least 70 based on a Stanford-Binet test that she refused to complete. She showed good reading, writing, and language comprehension skills, and the special abilities of hyperlexia, hypermnesia, and hypercalculia. However, she did not speak. Criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, and her Childhood Autism Rating Scale score of 36 indicated mild to moderate autism. She had severe electroencephalographic abnormalities: hypsarrhythmia, multifocal or generalized epileptiform discharges, and electrical status epilepticus during sleep, with a continuous left temporal focus. Magnetic resonance imaging showed many cortical tubers in all brain lobes, and subependymal nodules. We discuss possible explanations for her lack of speech. Considered as speech apraxia, her mutism could be either a symptom of her TSC or a component of her autism. Another possibility is that long-lasting electrical status epilepticus during sleep led to her autistic behavior and language arrest. Still another possibility is that a disinhibited mammalian target of rapamycin (mTOR) pathway was at the root of all of her neuropsychiatric symptoms. PMID:24968009

  9. A girl with tuberous sclerosis complex presenting with severe epilepsy and electrical status epilepticus during sleep, and with high-functioning autism and mutism.

    PubMed

    Pacheva, Iliyana; Panov, Georgi; Gillberg, Christopher; Neville, Brian

    2014-06-01

    Most patients with tuberous sclerosis complex (TSC) suffer from epilepsy, and many have cognitive and behavioral problems like severe intellectual disability, autism, and hyperactivity. Only rare patients with TSC and autism have a normal intelligence quotient. We report a 13-year-old girl with definite TSC who had early-onset severe epilepsy, autistic behavior, and moderate developmental delay. By school age, however, she had normal intelligence; her intelligence quotient was at least 70 based on a Stanford-Binet test that she refused to complete. She showed good reading, writing, and language comprehension skills, and the special abilities of hyperlexia, hypermnesia, and hypercalculia. However, she did not speak. Criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, and her Childhood Autism Rating Scale score of 36 indicated mild to moderate autism. She had severe electroencephalographic abnormalities: hypsarrhythmia, multifocal or generalized epileptiform discharges, and electrical status epilepticus during sleep, with a continuous left temporal focus. Magnetic resonance imaging showed many cortical tubers in all brain lobes, and subependymal nodules. We discuss possible explanations for her lack of speech. Considered as speech apraxia, her mutism could be either a symptom of her TSC or a component of her autism. Another possibility is that long-lasting electrical status epilepticus during sleep led to her autistic behavior and language arrest. Still another possibility is that a disinhibited mammalian target of rapamycin (mTOR) pathway was at the root of all of her neuropsychiatric symptoms.

  10. An Experiment to Determine the Effectiveness of Slides and Audio-Tapes for Presenting Manipulative Demonstrations in Graphic Arts.

    ERIC Educational Resources Information Center

    Jenkins, John David

    This study compared teacher demonstrations with a slide-tape methods of presenting demonstrations in graphic arts. It involved 134 eighth grade students and four teachers in four schools. Random assignment to treatments was made by classes. Four demonstrations randomly selected from a group were (1) composing a line of type, (2) locking-up a type…

  11. Application of Lean Six Sigma for patients presenting with ST-elevation myocardial infarction: the Hamilton Health Sciences experience.

    PubMed

    Aldarrab, Ayad

    2006-01-01

    Most patients with symptomatic acute myocardial infarction (AMI), the leading cause of death in western industrialized nations, use the emergency department (ED) as their point of entry. Yet, one identified barrier to early recognition of patients with AMI is ED overcrowding. In this paper, the author presents a quality improvement model that applies Lean Six Sigma guidelines to the clinical setting.

  12. Outcomes for Young Children's Social Status from Playing Group Games: Experiences from a Primary School in Hong Kong

    ERIC Educational Resources Information Center

    Liu, Sylvia; Yuen, Mantak; Rao, Nirmala

    2015-01-01

    This exploratory study involved a structured group-games intervention to develop first-grade students' social competence. The effects were evaluated by assessing possible outcomes for the children's social status. A sample of 119 first-grade, mixed-ability students from a Hong Kong primary school participated in the sessions (63 boys, 56 girls:…

  13. At Risk: The Relationship between Experiences of Child Sexual Abuse and Women's HIV Status in Papua New Guinea

    ERIC Educational Resources Information Center

    Lewis, Ione R.

    2012-01-01

    Child sexual abuse in Papua New Guinea is a human rights issue as well as an indicator of HIV risk in women. This study aimed to develop knowledge about the link between violence experienced by women and their HIV status. The study used a mixed method approach to collect quantitative and qualitative data through structured interviews with a sample…

  14. Status of Electrostatic Accelerometer Development for Gravity Recovery and Climate Experiment Follow-on Mission (GRACE FO)

    NASA Astrophysics Data System (ADS)

    Lebat, V.; Boulanger, D.; Christophe, B.; Foulon, B.; Liorzou, F.; Perrot, E.; Huynh, P. A.

    2014-12-01

    Critical Design Review is scheduled at the end of September 2014, and the integration of the first Flight Model will begin on October 2014. The results of the Engineering Model tests and the status of the Flight Models will be presented.

  15. Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia

    PubMed Central

    Al-Talib, Ayman A.

    2016-01-01

    Objectives: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. Materials and Methods: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient's age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation. Data was entered and analyzed using Excel; frequency distribution for categorical variables and descriptive statistics for continuous variables were computed. Results: Of a total of 25,000 deliveries in ten years, 22 cases of complete molar pregnancy were encountered: 0.9 cases of molar pregnancy per 1000 pregnancies. Majority of patients (63.7%) were older than 35 years, and were nulliparous (45.5%). The commonest symptom was vaginal bleeding (86.4%) followed by hyperemesis gravidarum (41.0%); Hyperthyroidism was seen in 1 patient (4.5%). Ovarian enlargement by theca-lutin cyst was seen in 3 patients (13.6%). The majority of patients (63.6%) had normal BhCG within 9 weeks (63 days) after suction curettage. The majority of the cases followed a benign course. Conclusion: Aged older than 35 years seems a risk factor and vaginal bleeding is the commonest presenting symptom. Early booking of pregnant women to antenatal care clinics and routine first trimester ultrasound made diagnosis easier and earlier before complications appear. PMID:27625583

  16. Clinical presentation and treatment outcome of molar pregnancy: Ten years experience at a Tertiary Care Hospital in Dammam, Saudi Arabia

    PubMed Central

    Al-Talib, Ayman A.

    2016-01-01

    Objectives: To study the clinical presentation and treatment outcome of molar pregnancy at a Tertiary Care Hospital in Dammam, Saudi Arabia. Materials and Methods: Reviewed medical records of all molar pregnancy cases among all the deliveries at a tertiary care hospital in Dammam from 2005 to 2014, after approval by institutional ethical review committee. Data abstracted included patient's age, parity, presenting symptoms, gestational age at diagnosis, uterine size, ultrasonographic findings, BhCG level at the time of diagnosis and at follow-up after evacuation, and blood loss during evacuation. Data was entered and analyzed using Excel; frequency distribution for categorical variables and descriptive statistics for continuous variables were computed. Results: Of a total of 25,000 deliveries in ten years, 22 cases of complete molar pregnancy were encountered: 0.9 cases of molar pregnancy per 1000 pregnancies. Majority of patients (63.7%) were older than 35 years, and were nulliparous (45.5%). The commonest symptom was vaginal bleeding (86.4%) followed by hyperemesis gravidarum (41.0%); Hyperthyroidism was seen in 1 patient (4.5%). Ovarian enlargement by theca-lutin cyst was seen in 3 patients (13.6%). The majority of patients (63.6%) had normal BhCG within 9 weeks (63 days) after suction curettage. The majority of the cases followed a benign course. Conclusion: Aged older than 35 years seems a risk factor and vaginal bleeding is the commonest presenting symptom. Early booking of pregnant women to antenatal care clinics and routine first trimester ultrasound made diagnosis easier and earlier before complications appear.

  17. Model experiments for immunomagnetic elimination of leukemic cells from human bone marrow. Presentation of a novel magnetic separation system.

    PubMed

    Gruhn, B; Häfer, R; Müller, A; Andrä, W; Danan, H; Zintl, F

    1991-11-01

    Optimal conditions for removing leukemic cells from human bone marrow with monoclonal antibodies (mAb) and magnetic immunobeads were investigated. Monodisperse 3 microns polystyrene microspheres containing magnetite were coated with affinity-purified rabbit antimouse IgG at 4 degrees C, pH 9.6 for 18 h. SKW-3 cells (T-CLL cell line) were marked with the supravital DNA stain Hoechst 33342, seeded into normal human bone marrow, and then incubated with the mAb CD1, CD6, and CD8 at 4 degrees C for 30 min. In preliminary experiments REH cells (cALL cells) and mouse anti-REH cell antibodies were used to find the most favorable conditions for the binding of magnetic beads to tumor cells. Optimal formation of cell-bead rosettes was achieved by rotating beads and tumor cells together at room temperature at a concentration of 1 x 10(7) cells/ml, a bead: tumor cell ratio of 100:1 and an incubation time of one hour. The novel magnetic separation apparatus consists of three polystyrene chambers connected by silicone rubber tubing. The chambers contain four steel inserts each equipped with 32 nickel wires, which are magnetized by permanent magnets in such a way that the inhomogeneous high gradient magnetic field could be established within the cell suspension containing the cells to be depleted. The fluid flow was established by a peristaltic pump. At a flow rate of 1.5 ml/min and a field strength of 160 kA/m, no beads could be detected in the purged marrow. A cocktail of the three mAb was more effective than any single antibody in forming bead-cell rosettes. Two sequential purging cycles were superior to one. The marrow recovered was highly viable as assessed by trypan blue dye exclusion and by growth of CFU-GM. PMID:1786986

  18. Model experiments for immunomagnetic elimination of leukemic cells from human bone marrow. Presentation of a novel magnetic separation system.

    PubMed

    Gruhn, B; Häfer, R; Müller, A; Andrä, W; Danan, H; Zintl, F

    1991-11-01

    Optimal conditions for removing leukemic cells from human bone marrow with monoclonal antibodies (mAb) and magnetic immunobeads were investigated. Monodisperse 3 microns polystyrene microspheres containing magnetite were coated with affinity-purified rabbit antimouse IgG at 4 degrees C, pH 9.6 for 18 h. SKW-3 cells (T-CLL cell line) were marked with the supravital DNA stain Hoechst 33342, seeded into normal human bone marrow, and then incubated with the mAb CD1, CD6, and CD8 at 4 degrees C for 30 min. In preliminary experiments REH cells (cALL cells) and mouse anti-REH cell antibodies were used to find the most favorable conditions for the binding of magnetic beads to tumor cells. Optimal formation of cell-bead rosettes was achieved by rotating beads and tumor cells together at room temperature at a concentration of 1 x 10(7) cells/ml, a bead: tumor cell ratio of 100:1 and an incubation time of one hour. The novel magnetic separation apparatus consists of three polystyrene chambers connected by silicone rubber tubing. The chambers contain four steel inserts each equipped with 32 nickel wires, which are magnetized by permanent magnets in such a way that the inhomogeneous high gradient magnetic field could be established within the cell suspension containing the cells to be depleted. The fluid flow was established by a peristaltic pump. At a flow rate of 1.5 ml/min and a field strength of 160 kA/m, no beads could be detected in the purged marrow. A cocktail of the three mAb was more effective than any single antibody in forming bead-cell rosettes. Two sequential purging cycles were superior to one. The marrow recovered was highly viable as assessed by trypan blue dye exclusion and by growth of CFU-GM.

  19. Autoimmune haemolytic anaemia: pattern of presentation and management outcome in a Nigerian population: a ten-year experience.

    PubMed

    Salawu, L; Durosinmi, M A

    2002-06-01

    Autoimmune haemolytic anaemia (AHA) is one of the commonest autoimmune disorders of man. It is characterised by the binding of anti-erythrocyte autoantibodies to red blood cells and destruction of the coated cells in the reticulo-endothelial system. Autoimnmune disorders are said to be rare in indigenous African population, probably due to the widespread infectious diseases, which impair host's T-cell immunity. This study is therefore aimed at investigating the pattern of presentation and management outcome of patients with AHA seen over a period of 10 years (June 1988 to May 1998) at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife. We retrospectively analysed the records of patients with respect to the clinical, haematological, biochemical and serological features of AHA seen within the study period. Diagnosis was based on laboratory features of haemolytic anaemia and/or a positive direct anti-human globulin (Coombs') test after excluding other causes of haemolytic anaemia. Treatment protocol and outcome were noted in all cases. We identified 13 patients with AHA (7 females, 6 males) aged 6-70 (median, 42) years. Six (42%) had secondary AHA and the remaining 8 presented with primary (idiopathic) AHA. Laboratory evidence of haemolysis (bone marrow erythroid hyperplasia and hyperbilirubinaemia) was found in all cases, while the direct Coomb's test was positive in 10 (76.9%) cases. All the patients had moderate-severe anaemia within the course of the disease, requiring blood transfusion. Remission was induced with prednisolone in all except three cases with secondary AHA who died of the primary disease before AHA could be controlled. Follow-up period post-remission ranged between 1 and 78 months. However, 2 (20%) are still being followed-up till the time of this report. This study agrees with the view that autoimmune disorders are not common in Nigerians, as documented for other Africans. It also shows that steroid therapy (prednisolone) is quite

  20. Dynamic sexual dichromatism produces a sex signal in an explosively breeding Neotropical toad: A model presentation experiment.

    PubMed

    Rehberg-Besler, Nicolas; Mennill, Daniel J; Doucet, Stéphanie M

    2015-12-01

    Many animals breed in large mating aggregations, where males must rapidly discriminate between prospective mates and rivals. Selection may favour features that facilitate rapid discrimination in these aggregations. The explosively breeding Neotropical Yellow Toad, Incilius luetkenii, exhibits a rapid and dramatic colour change; males change from a cryptic brown to a conspicuous lemon yellow for their brief breeding period. Females, in contrast, remain cryptic brown throughout the year. The function of this temporary, sex-specific colour change is unknown. We tested the hypothesis that yellow colouration displayed by male I. luetkenii facilitates sex recognition during both daytime and nighttime mating aggregations. We created yellow and brown model toads and presented them to males during a breeding event. Male I. luetkenii responded significantly more intensely to brown models compared to yellow models, approaching them and making more amplexus attempts on the brown versus yellow models. This strong pattern held true regardless of ambient light intensity, making this the first study to expose a dynamic colour signal that operates during both day and night. Our results indicate that male I. luetkenii use colouration to quickly discriminate between males and females during their brief, explosive mating aggregations. Our findings suggest that the rapid, dramatic colour change of male I. luetkenii facilitates sex recognition, which could provide a significant fitness advantage to males in the form of reduced energy expenditure and reduced risk of injury by other males. Dynamic dichromatism may provide similar fitness benefits in any organisms that mate in large, competitive aggregations.