30 CFR 282.20 - Obligations and responsibilities of lessees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the approved Delineation, Testing, or Mining Plans; and other written or oral orders or instructions issued by the Director when performing exploration, testing, development, and production activities..., testing, development, and production operations on the lease available to the Director for examination and...

Life in the dark: Roots and how they regulate plant-soil interactions

NASA Astrophysics Data System (ADS)

Wu, Y.; Chou, C.; Peruzzo, L.; Riley, W. J.; Hao, Z.; Petrov, P.; Newman, G. A.; Versteeg, R.; Blancaflor, E.; Ma, X.; Dafflon, B.; Brodie, E.; Hubbard, S. S.

2017-12-01

Roots play a key role in regulating interactions between soil and plants, an important biosphere process critical for soil development and health, global food security, carbon sequestration, and the cycling of elements (water, carbon, nutrients, and environmental contaminants). However, their underground location has hindered studies of plant roots and the role they play in regulating plant-soil interactions. Technological limitations for root phenotyping and the lack of an integrated approach capable of linking root development, its environmental adaptation/modification with subsequent impact on plant health and productivity are major challenges faced by scientists as they seek to understand the plant's hidden half. To overcome these challenges, we combine novel experimental methods with numerical simulations, and conduct controlled studies to explore the dynamic growth of crop roots. We ask how roots adapt to and change the soil environment and their subsequent impacts on plant health and productivity. Specifically, our efforts are focused on (1) developing novel geophysical approaches for non-invasive plant root and rhizosphere characterization; (2) correlating root developments with key canopy traits indicative of plant health and productivity; (3) developing numerical algorithms for novel geophysical root signal processing; (4) establishing plant growth models to explore root-soil interactions and above and below ground traits co-variabilities; and (5) exploring how root development modifies rhizosphere physical, hydrological, and geochemical environments for adaptation and survival. Our preliminary results highlight the potential of using electro-geophysical methods to quantifying key rhizosphere traits, the capability of the ecosys model for mechanistic plant growth simulation and traits correlation exploration, and the combination of multi-physics and numerical approach for a systematic understanding of root growth dynamics, impacts on soil physicochemical environments, and plant health and productivity.

Regional resource depletion and industry activity: The case of oil and gas in the Gulf of Mexico

USGS Publications Warehouse

Attanasi, E.D.

1986-01-01

Stable and declining oil and gas prices have changed the industry's price expectations and, along with depletion of promising exploration prospects, has resulted in reduced exploration. Even with intensive additional exploration, production in most U.S. areas is expected to decline. What does this imply for the drilling and petroleum industry suppliers in particular regions? How should planners in government and the private sector project and incorporate the consequences of these changes in their strategies? This paper answers these questions for the industry operating in the offshore Gulf of Mexico. Future oil and gas production, as well as demand for offshore drilling and production facilities, are shown to depend on the size distribution of undiscovered fields, their associated production costs, and oil and gas prices. Declining well productivity is a consequence of development of progressively smaller fields so that long-run drilling demand should not decline in proportion to the expected production decline. Calculations show a substantial payoff to the drilling industry, in terms of potential demand increases, if it can develop and implement cost reducing technologies. Implications of these results for other offshore producing areas such as the North Sea are also discussed. ?? 1986.

Socio-economic development of territories based on the principles of public-private partnership in the sphere of comprehensive mineral exploration

NASA Astrophysics Data System (ADS)

Nikitenko, S. M.; Goosen, E. V.

2017-09-01

The article explores the possibility of using instruments of public-private partnership for a paradigm shift in subsoil use in the fuel and energy complex of Russia. The modern Russian fuel and energy complex (FEC) is characterized by high depreciation of production assets, technological inferiority compared to the developed countries, etc. The solution to all these problems seems to be closely connected with the transition from extensive use of natural resources to comprehensive mineral exploration (CME), with a stable socio-economic development of territories and mutually beneficial partnership between science, business and government based on the principles of public-private partnership (PPP). The article discussed the three main directions of PPP projects development in subsoil use. The first direction comprises the projects aimed at the establishment of core mineral resource businesses on the basis of concession agreements and production sharing contracts. The second direction concerns the projects focused on the development of territories and objects of industrial and social infrastructure in resource regions. The third direction is formed by the projects aimed at the development of new industries, focused on the creation of centers of innovative development, formation of markets for innovative products and innovative clusters in the energy industry.

Teaching, learning, and planetary exploration

NASA Technical Reports Server (NTRS)

Brown, Robert A.

1992-01-01

The progress accomplished in the first five months of the three-year grant period of Teaching, Learning, and Planetary Exploration is presented. The objectives of this project are to discover new education products and services based on space science, particularly planetary exploration. An Exploration in Education is the umbrella name for the education projects as they are seen by teachers and the interested public. As described in the proposal, our approach consists of: (1) increasing practical understanding of the potential role and capabilities of the research community to contribute to basic education using new discoveries; (2) developing an intellectual framework for these contributions by supplying criteria and templates for the teacher's stories; (3) attracting astronomers, engineers, and technical staff to the project and helping them form productive education partnerships for the future, (4) exploring relevant technologies and networks for authoring and communicating the teacher's stories; (5) enlisting the participation of potential user's of the teacher's stories in defining the products; (6) actually producing and delivering many educationally useful teacher's stories; and (7) reporting the pilot study results with critical evaluation. Technical progress was made by assembling our electronic publishing stations, designing electronic publications based on space science, and developing distribution approaches for electronic products. Progress was made addressing critical issues by developing policies and procedures for securing intellectual property rights and assembling a focus group of teachers to test our ideas and assure the quality of our products. The following useful materials are being produced: the TOPS report; three electronic 'PictureBooks'; one 'ElectronicArticle'; three 'ElectronicReports'; ten 'PrinterPosters'; and the 'FaxForum' with an initial complement of printed materials. We have coordinated with planetary scientists and astronomers both at the technical and policy level to assure the efficiency and ultimate utility of these efforts to derive educational benefits from the space science and exploration program as a whole.

RISK REDUCTION WITH A FUZZY EXPERT EXPLORATION TOOL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert S. Balch; Ron Broadhead

2005-03-01

Incomplete or sparse data such as geologic or formation characteristics introduce a high level of risk for oil exploration and development projects. ''Expert'' systems developed and used in several disciplines and industries have demonstrated beneficial results when working with sparse data. State-of-the-art expert exploration tools, relying on a database, and computer maps generated by neural networks and user inputs, have been developed through the use of ''fuzzy'' logic, a mathematical treatment of imprecise or non-explicit parameters and values. Oil prospecting risk has been reduced with the use of these properly verified and validated ''Fuzzy Expert Exploration (FEE) Tools.'' Through themore » course of this project, FEE Tools and supporting software were developed for two producing formations in southeast New Mexico. Tools of this type can be beneficial in many regions of the U.S. by enabling risk reduction in oil and gas prospecting as well as decreased prospecting and development costs. In today's oil industry environment, many smaller exploration companies lack the resources of a pool of expert exploration personnel. Downsizing, volatile oil prices, and scarcity of domestic exploration funds have also affected larger companies, and will, with time, affect the end users of oil industry products in the U.S. as reserves are depleted. The FEE Tools benefit a diverse group in the U.S., allowing a more efficient use of scarce funds, and potentially reducing dependence on foreign oil and providing lower product prices for consumers.« less

Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties.

PubMed

Nijhara, Ruchika; Balakrishnan, Krishna

2006-06-01

Scientists and entrepreneurs who contemplate developing nanomedicine products face several unique challenges in addition to many of the traditional hurdles of product development. In this review we analyze the major physicochemical, biologic and functional characteristics of several nanomedicine products on the market and explore the question of what made them unique. What made them successful? We also focus on the regulatory challenges faced by nanomedicine product developers. Based on these analyses, we propose the factors that are most likely to contribute to the success of nanomedicine products.

FSU/Eastern Europe: Russia spearheads small upturn

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-08-01

The paper discusses the political and legal scene in Russia, domestic restructuring, exploration, drilling, development by Western companies and by Russian companies, and production. Exploration and development in Azerbaijan, Kazakhstan, Turkmenistan, Ukraine, Armenia, Belarus, Georgia, Kyrgyzstan, Latvia, Lithuania, Moldova, Tajikistan, Uzbekistan, Albania, Bulgaria, Croatia, Czech Republic, Hungary, Poland, Romania, Slovakia, Slovenia, and Serbia are also discussed.

"It's Not Like a Normal 9 to 5!": The Learning Journeys of Media Production Apprentices in Distributed Working Conditions

ERIC Educational Resources Information Center

Lahiff, Ann; Guile, David

2016-01-01

An apprenticeship in media production in England is at the centre of this case study exploration. The context is exemplified by the organisation of the process of production around project teams and the development of project-based working cultures. Given these developments, the working conditions and learning opportunities presented to…

The Learning Potential of Boundary Crossing in the Context of Product Introduction

ERIC Educational Resources Information Center

Gustavsson, Maria; Säfsten, Kristina

2017-01-01

The aim is to explore challenges related to the integration between product development and production in product introduction and, given these challenges, to analyse the learning potential of boundary crossing in the context of product introduction. The paper draws on evidence from a Swedish manufacturing company. The theoretical framework is…

75 FR 3753 - Agency Information Collection Activities: Comment Request for the USGS Mine, Development, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-22

... to make domestic ore resource analyses. Tabulations of volumetric data concerning domestic mining... mined and the resulting marketable product. These data are an indicator of the future mining outlook... the U.S. Geological Survey with domestic production, exploration, and mine development data for...

Creativity and Brain-Functioning in Product Development Engineers: A Canonical Correlation Analysis

ERIC Educational Resources Information Center

Travis, Frederick; Lagrosen, Yvonne

2014-01-01

This study used canonical correlation analysis to explore the relation among scores on the Torrance test of figural and verbal creativity and demographic, psychological and physiological measures in Swedish product-development engineers. The first canonical variate included figural and verbal flexibility and originality as dependent measures and…

Current Soviet exploration plays: Success and potential

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grace, J.D.

1991-03-01

Soviet hydrocarbon exploration in the 1980s took four distinct directions. First was extension exploration and the search for smaller new fields in discrete traps in traditional producing regions, such as the Apsheron Peninsula, North Caucasus, and Volga-Urals. This strategy produced a large number of small discoveries close to established infrastructure. Second was new field exploration in West Siberia in the stratigraphically complex Jurassic and the lower Neocomian sections. Third was expansion of the prolific gas plays in northern West Siberia. Exploratory success in West Siberia has created a backlog of several hundred discoveries awaiting full delineation and development. Most ofmore » these fields are distant from the established oil production center in the Middle Ob region and, therefore, may remain in inventory. Fourth was initial tests of new exploration frontiers, most important, the Paleozoic and Mesozoic plays of the Barents and Kara seas and the subsalt plays of the North Caspian basin. While these plays have yielded very important discoveries, significant technological barriers impede their development. The outlook for Soviet oil exploration in the 1990s is for significant opportunities for discovery of large volumes of oil, but at radically increasing exploration and production costs. In established regions, these costs arise from small field sizes and low well productivities. In frontier regions, exploitation of new fields will require technology not currently available in the USSR. The outlook for gas exploration continues to be very bright, as the onshore northern West Siberia is not fully explored and initial results from the Barents and Kara seas promise more very large gas discoveries.« less

Overview of NASA Technology Development for In-Situ Resource Utilization (ISRU)

NASA Technical Reports Server (NTRS)

Linne, Diane L.; Sanders, Gerald B.; Starr, Stanley O.; Eisenman, David J.; Suzuki, Nantel H.; Anderson, Molly S.; O'Malley, Terrence F.; Araghi, Koorosh R.

2017-01-01

In-Situ Resource Utilization (ISRU) encompasses a broad range of systems that enable the production and use of extraterrestrial resources in support of future exploration missions. It has the potential to greatly reduce the dependency on resources transported from Earth (e.g., propellants, life support consumables), thereby significantly improving the ability to conduct future missions. Recognizing the critical importance of ISRU for the future, NASA is currently conducting technology development projects in two of its four mission directorates. The Advanced Exploration Systems Division in the Agency's Human Exploration and Operations Mission Directorate has initiated a new project for ISRU Technology focused on component, subsystem, and system maturation in the areas of water volatiles resource acquisition, and water volatiles and atmospheric processing into propellants and other consumable products. The Space Technology Mission Directorate is supporting development of ISRU component technologies in the areas of Mars atmosphere acquisition, including dust management, and oxygen production from Mars atmosphere for propellant and life support consumables. Together, these two coordinated projects are working towards a common goal of demonstrating ISRU technology and systems in preparation for future flight applications.

Lunar Polar In Situ Resource Utilization (ISRU) as a Stepping Stone for Human Exploration

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.

2013-01-01

A major emphasis of NASA is to extend and expand human exploration across the solar system. While specific destinations are still being discussed as to what comes first, it is imperative that NASA create new technologies and approaches that make space exploration affordable and sustainable. Critical to achieving affordable and sustainable exploration beyond low Earth orbit (LEO) are the development of technologies and approaches for advanced robotics, power, propulsion, habitats, life support, and especially, space resource utilization systems. Space resources and how to use them, often called In-Situ Resource Utilization (ISRU), can have a tremendous beneficial impact on robotic and human exploration of the Moon, Mars, Phobos, and Near Earth Objects (NEOs), while at the same time helping to solve terrestrial challenges and enabling commercial space activities. The search for lunar resources, demonstration of extraterrestrial mining, and the utilization of resource-derived products, especially from polar volatiles, can be a stepping stone for subsequent human exploration missions to other destinations of interest due to the proximity of the Moon, complimentary environments and resources, and the demonstration of critical technologies, processes, and operations. ISRU and the Moon: There are four main areas of development interest with respect to finding, obtaining, extracting, and using space resources: Prospecting for resources, Production of mission critical consumables like propellants and life support gases, Civil engineering and construction, and Energy production, storage, and transfer. The search for potential resources and the production of mission critical consumables are the primary focus of current NASA technology and system development activities since they provide the greatest initial reduction in mission mass, cost, and risk. Because of the proximity of the Moon, understanding lunar resources and developing, demonstrating, and implementing lunar ISRU provides a near and early opportunity to perform the following that are applicable to other human exploration mission destinations: Identify and characterize resources, how they are distributed, and the material, location and environment in which they are found; Demonstrate concepts, technologies, and hardware that can reduce the cost and risk of human exploration beyond Earth orbit; Use the Moon for operation experience and mission validation for much longer missions that are farther from Earth Develop and evolve ISRU to support sustained, economical human presence beyond Earth's orbit, including promoting space commercialization As Table 1 depicts, the Moon provides environments and resources applicable to Mars and NEOs. Two lunar ISRU resource and product pathways that have notable synergism with NEO, Phobos/Demos, and Mars ISRU are oxygen/metal extraction from regolith, and water/volatile extraction from lunar polar materials. To minimize the risk of developing and incorporating ISRU into human missions, a phased implementation plan is recommended that starts with prospecting and demonstrating critical technologies on robotic and human missions, then performing pilot scale operations (in non-mission critical roles) to enhance exploration mission capabilities, leading to full utilization of space resources in mission critical roles. Which lunar ISRU pathway is followed will depend on the results of early resource prospecting/proof-ofconcept mission(s), and long-term human exploration plans.

75 FR 6175 - Notice of Intent to Prepare an Environmental Impact Statement on the Effects of Oil and Gas...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... taking of marine mammals incidental to offshore exploration activities (e.g., seismic surveys and... drilling operations during the open water season in order for the industry to drill priority exploration..., helps to optimally locate exploration and development wells, maximizing extraction and production from a...

Beneficial Effects of Marine Algal Compounds in Cosmeceuticals

PubMed Central

Thomas, Noel Vinay; Kim, Se-Kwon

2013-01-01

The name “cosmeceuticals” is derived from “cosmetics and pharmaceuticals”, indicating that a specific product contains active ingredients. Marine algae have gained much importance in cosmeceutical product development due to their rich bioactive compounds. In the present review, marine algal compounds (phlorotannins, sulfated polysaccharides and tyrosinase inhibitors) have been discussed toward cosmeceutical application. In addition, atopic dermatitis and the possible role of matrix metalloproteinase (MMP) in skin-related diseases have been explored extensively for cosmeceutical products. The proper development of marine algae compounds will be helpful in cosmeceutical product development and in the development of the cosmeceutical industry. PMID:23344156

Ecological Production Functions: A Theoretical and Practical Exploration

EPA Science Inventory

Ecological production functions characterize relationships between ecosystem condition, management practices, and the delivery of economically valuable ecosystem services. Many in the ecosystem service research community view ecological research directed toward developing ecolog...

Combining high-resolution gross domestic product data with home and personal care product market research data to generate a subnational emission inventory for Asia.

PubMed

Hodges, Juliet Elizabeth Natasha; Vamshi, Raghu; Holmes, Christopher; Rowson, Matthew; Miah, Taqmina; Price, Oliver Richard

2014-04-01

Environmental risk assessment of chemicals is reliant on good estimates of product usage information and robust exposure models. Over the past 20 to 30 years, much progress has been made with the development of exposure models that simulate the transport and distribution of chemicals in the environment. However, little progress has been made in our ability to estimate chemical emissions of home and personal care (HPC) products. In this project, we have developed an approach to estimate subnational emission inventory of chemical ingredients used in HPC products for 12 Asian countries including Bangladesh, Cambodia, China, India, Indonesia, Laos, Malaysia, Pakistan, Philippines, Sri Lanka, Thailand, and Vietnam (Asia-12). To develop this inventory, we have coupled a 1 km grid of per capita gross domestic product (GDP) estimates with market research data of HPC product sales. We explore the necessity of accounting for a population's ability to purchase HPC products in determining their subnational distribution in regions where wealth is not uniform. The implications of using high resolution data on inter- and intracountry subnational emission estimates for a range of hypothetical and actual HPC product types were explored. It was demonstrated that for low value products (<500 US$ per capita/annum required to purchase product) the maximum deviation from baseline (emission distributed via population) is less than a factor of 3 and it would not result in significant differences in chemical risk assessments. However, for other product types (>500 US$ per capita/annum required to purchase product) the implications on emissions being assigned to subnational regions can vary by several orders of magnitude. The implications of this on conducting national or regional level risk assessments may be significant. Further work is needed to explore the implications of this variability in HPC emissions to enable the HPC industry and/or governments to advance risk-based chemical management policies in emerging markets. © 2013 SETAC.

Investigating Nature's Mysteries for Drug Development

Cancer.gov

More than half of the drugs approved to treat cancer come from a natural product or a natural product prototype. Scientists in NCI-Frederick's Natural Products Branch are exploring ways to harness chemicals produced by marine invertebrates, other animals, plants, and microbes for cancer drug discovery.

Cobalt mineral exploration and supply from 1995 through 2013

USGS Publications Warehouse

Wilburn, David R.

2011-01-01

The global mining industry has invested a large amount of capital in mineral exploration and development over the past 15 years in an effort to ensure that sufficient resources are available to meet future increases in demand for minerals. Exploration data have been used to identify specific sites where this investment has led to a significant contribution in global mineral supply of cobalt or where a significant increase in cobalt production capacity is anticipated in the next 5 years. This report provides an overview of the cobalt industry, factors affecting mineral supply, and circumstances surrounding the development, or lack thereof, of key mineral properties with the potential to affect mineral supply. Of the 48 sites with an effective production capacity of at least 1,000 metric tons per year of cobalt considered for this study, 3 producing sites underwent significant expansion during the study period, 10 exploration sites commenced production from 1995 through 2008, and 16 sites were expected to begin production by 2013 if planned development schedules are met. Cobalt supply is influenced by economic, environmental, political, and technological factors affecting exploration for and production of copper, nickel, and other metals as well as factors affecting the cobalt industry. Cobalt-rich nickel laterite deposits were discovered and developed in Australia and the South Pacific and improvements in laterite processing technology took place during the 1990s and early in the first decade of the 21st century when mining of copper-cobalt deposits in Congo (Kinshasa) was restricted because of regional conflict and lack of investment in that country's mining sector. There was also increased exploration for and greater importance placed on cobalt as a byproduct of nickel mining in Australia and Canada. The emergence of China as a major refined cobalt producer and consumer since 2007 has changed the pattern of demand for cobalt, particularly from Africa and Australasia. Chinese companies are increasingly becoming involved in copper and cobalt exploration and mining in Congo (Kinshasa) and Zambia as well as nickel, copper, and other mining in Australia and the South Pacific. Between 2009 and 2013, mines with a cumulative capacity of more than 100,000 metric tons per year of cobalt were proposed to come into production if all sites came into production as scheduled. This additional capacity corresponds to 175 percent of the 2008 global refinery production level. About 45 percent of this cobalt would be from primary nickel deposits, about 32 percent from primary copper deposits, and about 21 percent from primary cobalt deposits. By 2013, about 40 percent of new capacity was expected to come from the African Copperbelt; 38 percent, from Australia and the South Pacific countries of Philippines, Indonesia, New Caledonia, and Papua New Guinea; 11 percent, from other African countries; 5 percent, from North America; and 6 percent, from other areas.

Garden Banks 388 subsea drilling/production template: Project management of a fast-track project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ledbetter, W.R.

1995-10-01

Enserch Exploration`s Garden Banks 388 development is a production scheme based around a floating drilling and production facility and subsea drilling/production template. The Floating Production Facility (FPF) is a converted semisubmersible drilling rig which will drill and product through a 24-well slot template. This development is located in Block 388 of the Garden Banks area in the Gulf of Mexico approximately 200 miles southwest of New Orleans. Louisiana. This production system is being installed in an area of known oil and gas reserves and will produce to a shallow water platform 54 miles away at Ewing Bank 315. The FPFmore » will be permanently moored on the surface above the template. The subsea template has been installed in 2,190 feet of water and will produce through a 2,000 foot free-standing production riser system to the FPF. The produced fluids are partially separated on the FPF before oil and gas are pumped through the template to export gathering lines which are connected to the shallow water facility.« less

Development of Metric for Measuring the Impact of RD&D Funding on GTO's Geothermal Exploration Goals (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jenne, S.; Young, K. R.; Thorsteinsson, H.

The Department of Energy's Geothermal Technologies Office (GTO) provides RD&D funding for geothermal exploration technologies with the goal of lowering the risks and costs of geothermal development and exploration. In 2012, NREL was tasked with developing a metric to measure the impacts of this RD&D funding on the cost and time required for exploration activities. The development of this metric included collecting cost and time data for exploration techniques, creating a baseline suite of exploration techniques to which future exploration and cost and time improvements could be compared, and developing an online tool for graphically showing potential project impacts (allmore » available at http://en.openei.org/wiki/Gateway:Geothermal). The conference paper describes the methodology used to define the baseline exploration suite of techniques (baseline), as well as the approach that was used to create the cost and time data set that populates the baseline. The resulting product, an online tool for measuring impact, and the aggregated cost and time data are available on the Open EI website for public access (http://en.openei.org).« less

A Roundtable Discussion: Combination Products: Twice the Challenge?

PubMed

Baird, Nolan; Binion, Steven B; Cammack, Jon; Paine, Stephanie Del; Gonzales, Rosemary; Passut, Jena; Weiner, John Barlow Barr

2015-01-01

Combination products are therapeutic or diagnostic medical products that combine drugs, devices, and/or biological products with one another. FDA developed a regulation (final rule) on Current Good Manufacturing Practices (CGMP) for combination products that became effective July 22, 2013 (21 CFR Part 4). AAMI recently developed a technical information report (TIR) that provides information on how to effectively implement FDA's regulation. The overall goal of the TIR is to aid informed, risk-based decisions in establishing CGMP operating systems that support development, manufacture, premarket regulatory evaluation, and ultimately commercialization of combination products. This article, a result of an discussion with industry and FDA representatives, explores the landscape of combination products, highlights important considerations in developing and seeking marketing clearance for these innovative products, and provides insight on trends in the area.

[From manual workshop to international standard maker: exploration on production standard of acupuncture needle by Chengjiang acupuncture school].

PubMed

Cheng, Jie; Cao, Yang; Xia, Youbing

2015-02-01

ABSTRACT The exploration course on production standard of acupuncture needle by Chengjiang acupuncture school is reviewed in this paper. After new China was established, acupuncture needle standard was unified by Mr. CHENG Dan-an, which guided Suzhou Hua Erfang (predecessor of Suzhou Medical Supplies Factory) to make the quality standards and testing methods of acupuncture needle and improved the production process to make the modern acupuncture needle. Based on this, Suzhou Medical Supplies Factory followed the time development pace, ac tively introduced new technology, carried out technological innovation, and constantly improved the level of production technology, as a result, it gradually developed into one of the world's largest acupuncture needle production suppliers. Meanwhile, after establishing China's first national standard on acupuncture needle (GB 2024-1980), the Suzhou Medical Supplies Factory took the lead to draft "ISO) 17218:2014 the disposable use asepsis acupuncture needle", which was officially published as an international standard. The Suzhou Medical Supplies Factory developed from a manual workshop to an international standard maker.

It's More than an Art Project. Activity.

ERIC Educational Resources Information Center

Wright, Phyllis; Wright, Thomas

1998-01-01

Shows how a first-grade class explored the activities that are completed by people who design products, develop production systems, use materials and machines to make goods, and market the output from manufacturing plants. (JOW)

Controlled environment life support system: Growth studies with potatoes

NASA Technical Reports Server (NTRS)

Tibbitts, T. W.; Wheeler, R. M.

1986-01-01

Results of experiments conducted to maximize the productivity of potatoes grown under controlled environmental conditions are discussed. A variety of parameters is examined which affect potato growth, specifically, photoperiod, light intensity, temperature, nitrogen nutrition, carbon dioxide concentration and culture techniques. These experiments were conducted using five different cultivars, Russet Burbank, Norchip, Superior, Kennebec and Norland. To achieve high productivity, three specific objectives were explored: (1) to develop effective cultural procedures, (2) to determine the most effective photoperiod and (3) to develop a mist culture system. It is felt that the productivity obtained in this study is below the maximum that can be obtained. High irradiance levels coupled with tuber-promoting conditions such as cooler temperatures, increased CO2 levels and lowered nitrogen concentrations should allow increases in tuber production. Tuberization appears to be accelerated by short daylengths although final yields are not increased. Mist culture techniques have not yet produced fully developed tubers. The use of supporting media and alteration of the nitrogen content of the mist solution are being explored as a way to allow tubers to develop to maturity.

Low Latency DESDynI Data Products for Disaster Response, Resource Management and Other Applications

NASA Technical Reports Server (NTRS)

Doubleday, Joshua R.; Chien, Steve A.; Lou, Yunling

2011-01-01

We are developing onboard processor technology targeted at the L-band SAR instrument onboard the planned DESDynI mission to enable formation of SAR images onboard opening possibilities for near-real-time data products to augment full data streams. Several image processing and/or interpretation techniques are being explored as possible direct-broadcast products for use by agencies in need of low-latency data, responsible for disaster mitigation and assessment, resource management, agricultural development, shipping, etc. Data collected through UAVSAR (L-band) serves as surrogate to the future DESDynI instrument. We have explored surface water extent as a tool for flooding response, and disturbance images on polarimetric backscatter of repeat pass imagery potentially useful for structural collapse (earthquake), mud/land/debris-slides etc. We have also explored building vegetation and snow/ice classifiers, via support vector machines utilizing quad-pol backscatter, cross-pol phase, and a number of derivatives (radar vegetation index, dielectric estimates, etc.). We share our qualitative and quantitative results thus far.

Process to Product.

ERIC Educational Resources Information Center

Harrison, Gary, Ed.; Mirkes, Donna Z., Ed.

Intended for educators who direct federally funded model projects, the booklet provides a framework for special education product development. In "Making Media Decisions," G. Richman explores procedures for selecting the most appropriate medium to carry the message of a given product. The fundamental questions are addressed: what is the goal; who…

Discoveries, developments boost interest in Bangladesh

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-11-11

The government of Bangladesh is expected to open a new exploration licensing round by yearend, following approval of a new model production sharing contract this fall. Initial interest in new licenses from international companies is high, and a number of new contracts are expected to be signed in 1997. State firm Petrobangla is expected to give companies 90 days to submit bids once the exploration round is announced. It is now known whether the round will include rights to undeveloped or partially developed fields. Discovery of multipay Sangu gas field by Cairn Energy plc, Edinburgh, early this year created greatmore » interest among international companies. The analyst estimated Sangu reserves at 1 tcf of gas. Sangu, on Block 16 in the Bay of Bengal, is being considered for development with a small production platform and a pipeline to shore. The paper discusses the existing licenses and production prospects.« less

Exploration Rover Concepts and Development Challenges

NASA Technical Reports Server (NTRS)

Zakrajsek, James J.; McKissock, David B.; Woytach, Jeffrey M.; Zakrajsek, June F.; Oswald, Fred B.; McEntire, Kelly J.; Hill, Gerald M.; Abel, Phillip; Eichenberg, Dennis J.; Goodnight, Thomas W.

2005-01-01

This paper presents an overview of exploration rover concepts and the various development challenges associated with each as they are applied to exploration objectives and requirements for missions on the Moon and Mars. A variety of concepts for surface exploration vehicles have been proposed since the initial development of the Apollo-era lunar rover. This paper provides a brief description of the rover concepts, along with a comparison of their relative benefits and limitations. In addition, this paper outlines, and investigates a number of critical development challenges that surface exploration vehicles must address in order to successfully meet the exploration mission vision. These include: mission and environmental challenges, design challenges, and production and delivery challenges. Mission and environmental challenges include effects of terrain, extreme temperature differentials, dust issues, and radiation protection. Design methods are discussed that focus on optimum methods for developing highly reliable, long-life and efficient systems. In addition, challenges associated with delivering a surface exploration system is explored and discussed. Based on all the information presented, modularity will be the single most important factor in the development of a truly viable surface mobility vehicle. To meet mission, reliability, and affordability requirements, surface exploration vehicles, especially pressurized rovers, will need to be modularly designed and deployed across all projected Moon and Mars exploration missions.

Exploring Group Communication and Productivity Improvement: Using an Experiential Process.

ERIC Educational Resources Information Center

Mandeville, Mary Y.; Mandeville, David E.

Engineering students at Oklahoma State University used an experiential process (the ACME Basket Exercise) to develop an understanding of how quality and productivity can be improved. The exercise simulates a traditional production organization in the classroom and mirrors the efforts, the successes, and the frustrations of individuals and work…

Data Management for Mars Exploration Rovers

NASA Technical Reports Server (NTRS)

Snyder, Joseph F.; Smyth, David E.

2004-01-01

Data Management for the Mars Exploration Rovers (MER) project is a comprehensive system addressing the needs of development, test, and operations phases of the mission. During development of flight software, including the science software, the data management system can be simulated using any POSIX file system. During testing, the on-board file system can be bit compared with files on the ground to verify proper behavior and end-to-end data flows. During mission operations, end-to-end accountability of data products is supported, from science observation concept to data products within the permanent ground repository. Automated and human-in-the-loop ground tools allow decisions regarding retransmitting, re-prioritizing, and deleting data products to be made using higher level information than is available to a protocol-stack approach such as the CCSDS File Delivery Protocol (CFDP).

How children explore the phonological network in child-directed speech: A survival analysis of children’s first word productions

PubMed Central

Carlson, Matthew T.; Sonderegger, Morgan; Bane, Max

2014-01-01

We explored how phonological network structure influences the age of words’ first appearance in children’s (14–50 months) speech, using a large, longitudinal corpus of spontaneous child-caregiver interactions. We represent the caregiver lexicon as a network in which each word is connected to all of its phonological neighbors, and consider both words’ local neighborhood density (degree), and also their embeddedness among interconnected neighborhoods (clustering coefficient and coreness). The larger-scale structure reflected in the latter two measures is implicated in current theories of lexical development and processing, but its role in lexical development has not yet been explored. Multilevel discrete-time survival analysis revealed that children are more likely to produce new words whose network properties support lexical access for production: high degree, but low clustering coefficient and coreness. These effects appear to be strongest at earlier ages and largely absent from 30 months on. These results suggest that both a word’s local connectivity in the lexicon and its position in the lexicon as a whole influences when it is learned, and they underscore how general lexical processing mechanisms contribute to productive vocabulary development. PMID:25089073

Developing Advanced Human Support Technologies for Planetary Exploration Missions

NASA Technical Reports Server (NTRS)

Berdich, Debra P.; Campbell, Paul D.; Jernigan, J. Mark

2004-01-01

The United States Vision for Space Exploration calls for sending robots and humans to explore the Earth's moon, the planet Mars, and beyond. The National Aeronautics and Space Administration (NASA) is developing a set of design reference missions that will provide further detail to these plans. Lunar missions are expected to provide a stepping stone, through operational research and evaluation, in developing the knowledge base necessary to send crews on long duration missions to Mars and other distant destinations. The NASA Exploration Systems Directorate (ExSD), in its program of bioastronautics research, manages the development of technologies that maintain human life, health, and performance in space. Using a system engineering process and risk management methods, ExSD's Human Support Systems (HSS) Program selects and performs research and technology development in several critical areas and transfers the results of its efforts to NASA exploration mission/systems development programs in the form of developed technologies and new knowledge about the capabilities and constraints of systems required to support human existence beyond Low Earth Orbit. HSS efforts include the areas of advanced environmental monitoring and control, extravehicular activity, food technologies, life support systems, space human factors engineering, and systems integration of all these elements. The HSS Program provides a structured set of deliverable products to meet the needs of exploration programs. These products reduce the gaps that exist in our knowledge of and capabilities for human support for long duration, remote space missions. They also reduce the performance gap between the efficiency of current space systems and the greater efficiency that must be achieved to make human planetary exploration missions economically and logistically feasible. In conducting this research and technology development program, it is necessary for HSS technologists and program managers to develop a common currency for decision making and the allocation of funding. A high level assessment is made of both the knowledge gaps and the system performance gaps across the program s technical project portfolio. This allows decision making that assures proper emphasis areas and provides a key measure of annual technological progress, as exploration mission plans continue to mature.

Developing Advanced Support Technologies for Planetary Exploration Missions

NASA Technical Reports Server (NTRS)

Berdich, Debra P.; Campbel, Paul D.; Jernigan, J. Mark

2004-01-01

The United States Vision for Space Exploration calls for sending robots and humans to explore the Earth s moon, the planet Mars, and beyond. The National Aeronautics and Space Administration (NASA) is developing a set of design reference missions that will provide further detail to these plans. Lunar missions are expected to provide a stepping stone, through operational research and evaluation, in developing the knowledge base necessary to send crews on long duration missions to Mars and other distant destinations. The NASA Exploration Systems Directorate (ExSD), in its program of bioastronautics research, manages the development of technologies that maintain human life, health, and performance in space. Using a systems engineering process and risk management methods, ExSD s Human Support Systems (HSS) Program selects and performs research and technology development in several critical areas and transfers the results of its efforts to NASA exploration mission/systems development programs in the form of developed technologies and new knowledge about the capabilities and constraints of systems required to support human existence beyond Low Earth Orbit. HSS efforts include the areas of advanced environmental monitoring and control, extravehicular activity, food technologies, life support systems, space human factors engineering, and systems integration of all these elements. The HSS Program provides a structured set of deliverable products to meet the needs of exploration programs. these products reduce the gaps that exist in our knowledge of and capabilities for human support for long duration, remote space missions. They also reduce the performance gap between the efficiency of current space systems and the greater efficiency that must be achieved to make human planetary exploration missions economically and logistically feasible. In conducting this research and technology development program, it is necessary for HSS technologists and program managers to develop a common currency for decision making and the allocation of funding. A high level assessment is made of both the knowledge gaps and the system performance gaps across the program s technical project portfolio. This allows decision making that assures proper emphasis areas and provides a key measure of annual technological progress, as exploration mission plans continue to mature.

New Thematic Solar System Exploration Products for Scientists and Educators

NASA Technical Reports Server (NTRS)

Lowes, Lesile; Wessen, Alice; Davis, Phil; Lindstrom, Marilyn

2004-01-01

The next several years are an exciting time in the exploration of the solar system. NASA and its international partners have a veritable armada of spaceships heading out to the far reaches of the solar system. We'll send the first spacecraft beyond our solar system into interstellar space. We'll launch our first mission to Pluto and the Kuiper Belt and just our second to Mercury (the first in 30 years). We'll continue our intensive exploration of Mars and begin our detailed study of Saturn and its moons. We'll visit asteroids and comets and bring home pieces of the Sun and a comet. This is truly an unprecedented period of exploration and discovery! To facilitate access to information and to provide the thematic context for these missions NASA s Solar System Exploration Program and Solar System Exploration Education Forum have developed several products.

The Concept and Analytical Investigation of CO2 and Steam Co-Electrolysis for Resource Utilization in Space Exploration

NASA Technical Reports Server (NTRS)

McKellar, Michael G.; Stoots, Carl M.; Sohal, Manohar S.; Mulloth, Lila M.; Luna, Bernadette; Abney, Morgan B.

2010-01-01

CO2 acquisition and utilization technologies will have a vital role in designing sustainable and affordable life support and in situ fuel production architectures for human and robotic exploration of Moon and Mars. For long-term human exploration to be practical, reliable technologies have to be implemented to capture the metabolic CO2 from the cabin air and chemically reduce it to recover oxygen. Technologies that enable the in situ capture and conversion of atmospheric CO2 to fuel are essential for a viable human mission to Mars. This paper describes the concept and mathematical analysis of a closed-loop life support system based on combined electrolysis of CO2 and steam (co-electrolysis). Products of the coelectrolysis process include oxygen and syngas (CO and H2) that are suitable for life support and synthetic fuel production, respectively. The model was developed based on the performance of a co-electrolysis system developed at Idaho National Laboratory (INL). Individual and combined process models of the co-electrolysis and Sabatier, Bosch, Boudouard, and hydrogenation reactions are discussed and their performance analyses in terms of oxygen production and CO2 utilization are presented.

Times are taxing for UK companies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steven, R.R.

1982-06-20

Despite excellent prospects for new petroleum discoveries in the United Kingdom sector of the North Sea, a drop of oil prices and taxation has caused a slow down in development activities. Gas exploration is beginning to attract attention because of higher prices and a new bill which allows oil companies to sell gas directly to industry. A site licensing project by the government is expected to boost exploration. Recent exploration in the Norwegian sector has confirmed sufficient reserves to maintain current production levels for the next century. Reserves of natural gas were also appraised, particularly in the Sleipner area. Amore » gas-gathering pipeline system has been planned for dry and wet gases. Oil production has declined since 1980, but with new platforms, production is expected to increase. (JBF)« less

Recent development on sustainable biodiesel production using sewage sludge.

PubMed

Srivastava, Neha; Srivastava, Manish; Gupta, Vijai Kumar; Manikanta, Ambepu; Mishra, Kajal; Singh, Shipra; Singh, Sangram; Ramteke, P W; Mishra, P K

2018-05-01

Biodiesel as a renewable energy is an important alternative to biofuels in current scenario to explore green energy sources. It is well known that the major cost involved in biodiesel production technology is dependent upon the used feedstock. This review presents an overview of biodiesel production using municipal sewage sludge as a cost-effective substrate. Municipal sewage sludge which possesses high lipid content with zero cost availability can meet the characteristics of a potential feedstock to produce biodiesel. Different types of substrates based processes to produce biodiesel have been also explored in brief. In addition, limitations of the existing process technology for biodiesel production with sustainable solutions have been also discussed.

Space Resource Roundtable Rationale

NASA Astrophysics Data System (ADS)

Duke, Michael

1999-01-01

Recent progress in the U.S. Space Program has renewed interest in space resource issues. The Lunar Prospector mission conducted in NASA's Discovery Program has yielded interesting new insights into lunar resource issues, particularly the possibility that water is concentrated in cold traps at the lunar poles. This finding has not yet triggered a new program of lunar exploration or development, however it opens the possibility that new Discovery Missions might be viable. Several asteroid missions are underway or under development and a mission to return samples from the Mars satellite, Phobos, is being developed. These exploration missions are oriented toward scientific analysis, not resource development and utilization, but can provide additional insight into the possibilities for mining asteroids. The Mars Surveyor program now includes experiments on the 2001 lander that are directly applicable to developing propellants from the atmosphere of Mars, and the program has solicited proposals for the 2003/2005 missions in the area of resource utilization. These are aimed at the eventual human exploration of Mars. The beginning of construction of the International Space Station has awakened interest in follow-on programs of human exploration, and NASA is once more studying the human exploration of Moon, Mars and asteroids. Resource utilization will be included as objectives by some of these human exploration programs. At the same time, research and technology development programs in NASA such as the Microgravity Materials Science Program and the Cross-Enterprise Technology Development Program are including resource utilization as a valid area for study. Several major development areas that could utilize space resources, such as space tourism and solar power satellite programs, are actively under study. NASA's interests in space resource development largely are associated with NASA missions rather than the economic development of resources for industrial processes. That is why there is an emphasis in NASA programs on propellant production on Mars - NASA plans missions to Mars, so could make use of those propellants. For other types of applications, however, it will be up to market forces to define the materials and products needed and develop the technologies for extracting them from space resources. Some leading candidates among the potential products from space resources are propellants for other space activities, water from the Moon for use in space, silicon for photovoltaic energy collection in space, and, eventually, He-3 from the Moon for fusion energy production. As the capabilities for manufacturing materials in space are opened up by research aboard the International Space Station, new opportunities for utilization of space resources may emerge. Whereas current research emphasizes increasing knowledge, one program objective should be the development of industrial production techniques for space. These will be based on the development of value-added processing in space, where materials are brought to the space facility, processed there, and returned to Earth. If enough such space processing is developed that the materials transportation requirements are measured in the hundreds of tons a year level, opportunities for substituting lunar materials may develop. The fundamental message is that it is not possible to develop space resources in a vacuum. One must have three things: a recoverable resource, technology to recover it, and a customer. Of these, the customer probably is the most important. All three must be integrated in a space resource program. That is what the Space Resource Roundtable, initiated with this meeting, will bring together.

Strategies for cost-effective and enhanced production of bacterial cellulose.

PubMed

Islam, Mazhar Ul; Ullah, Muhammad Wajid; Khan, Shaukat; Shah, Nasrullah; Park, Joong Kon

2017-09-01

Bacterial cellulose (BC) has received substantial attention because of its high purity, mechanical strength, crystallinity, liquid-absorbing capabilities, biocompatibility, and biodegradability etc. These properties allow BC to be used in various fields, especially in industries producing medical, electronic, and food products etc. A major discrepancy associated with BC is its high production cost, usually much higher than the plant cellulose. To address this limitations, researchers have developed several strategies for enhanced production of BC including the designing of advanced reactors and utilization of various carbon sources. Another promising approach is the production of BC from waste materials such as food, industrial, agricultural, and brewery wastes etc. which not only reduces the overall BC production cost but is also environment-friendly. Besides, exploration of novel and efficient BC producing microbial strains provides impressive boost to the BC production processes. To this end, development of genetically engineered microbial strains has proven useful for enhanced BC production. In this review, we have summarized major efforts to enhance BC production in order to make it a cost-effective biopolymer. This review can be of interest to researchers investigating strategies for enhanced BC production, as well as companies exploring pilot projects to scale up BC production for industrial applications. Copyright © 2017 Elsevier B.V. All rights reserved.

Long-Term Trends in Loblolly Pine Site Productivity and Stand Characteristics Observed at the Impac Research Site in Alachua County, Florida

Treesearch

Timothy A. Martin; Eric J. Jokela

2002-01-01

While nutrient availability is a dominant factor controlling leaf area development and pine productivity in the southeastern USA, few studies have explored the long-term interactions among nutrient inputs, canopy foliage production, and aboveground biomass production. In order to address these questions, the Intensive Management Practices Assessment Center (IMPAC)...

Exploring the Classroom Practice of Productive Pedagogies of the Malaysian Secondary School Geography Teacher

ERIC Educational Resources Information Center

Ahmad@Shaari, Mohammad Zohir; Jamil, Hazri; Razak, Nordin Abd

2012-01-01

The productive pedagogies as a framework to enhance teaching and learning outcomes were developed by Lingard et al. (2001) consisted of four main dimensions--intellectual quality, connectedness, supportive classroom environment, and working with and valuing differences. This study is to investigate the productive pedagogical practices among…

The Historical Role of the Production Function in Economics and Business

ERIC Educational Resources Information Center

Gordon, David; Vaughan, Richard

2011-01-01

The production function explains a basic technological relationship between scarce resources, or inputs, and output. This paper offers a brief overview of the historical significance and operational role of the production function in business and economics. The origin and development of this function over time is initially explored. Several…

Integrated Solar System Exploration Education and Public Outreach: Theme, Products and Activities

NASA Technical Reports Server (NTRS)

Lowes, Leslie; Lindstrom, Marilyn; Stockman, Stephanie; Scalice, Daniela; Allen, Jaclyn; Tobola, Kay; Klug, Sheri; Harmon, Art

2004-01-01

NASA's Solar System Exploration Program is entering an unprecedented period of exploration and discovery. Its goal is to understand the origin and evolution of the solar system and life within it. SSE missions are operating or in development to study the far reaches of our solar system and beyond. These missions proceed in sequence for each body from reconnaissance flybys through orbiters and landers or rovers to sample returns. SSE research programs develop new instruments, analyze mission data or returned samples, and provide experimental or theoretical models to aid in interpretation.

Development of a quarterly referral productivity report.

PubMed

Wu, Cai; Sandoval, Alex; Hicks, Katrina N; Edwards, Tim J; Green, Lyle D

2007-10-11

The Office of Physician Relations at The University of Texas M. D. Anderson Cancer Center (MDACC) has developed a dynamic referral productivity reporting tool for its Multidisciplinary Care Centers (MCC). The tool leverages information within the institution's Enterprise Information Warehouse (EIW) using business intelligent software Hyperion Intelligent Explorer Suite 8.3. the referral productivity reports are intended to provide each MCC with detailed referral and registration data outlining how, and from where, patients arrive here for treatment. The reports supports operational and strategic initiatives aimed at improving referral processes and market related program development.

Compilation of geothermal information: exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-01-01

The Database for Geothermal Energy Exploration and Evaluation is a printout of selected references to publications covering the development of geothermal resources from the identification of an area to the production of elecric power. This annotated bibliography contains four sections: references, author index, author affiliation index, and descriptor index.

"I Don't Like Hearing Angel and Not Seeing Her! Why Did We Do That?" An Exploration of Students' Media Literacy Development through Production

ERIC Educational Resources Information Center

Luchs, Michele; Emery, Winston

2004-01-01

In this exploratory case study we look at student media production to find out what students know and have learned about the media through production work. We used a media education conceptual framework developed by Dick as a means of describing the day to day media learning of a group of ten students, four girls and six boys, producing a video…

Career Development during Childhood and Adolescence

ERIC Educational Resources Information Center

Porfeli, Erik J.; Lee, Bora

2012-01-01

In this article, the authors offer a general perspective of vocational identity development as central to child and adolescent career development. A review of the pertinent literatures suggests that identity development is the product of three development strands--career exploration, commitment, and reconsideration--that appear to begin during…

Why Tweet When You Can Bubble? Students' Perceptions of a Voice Microblog for the Development of Their L2 Spoken Production Skills

ERIC Educational Resources Information Center

Davies, Renaud Jonathan

2015-01-01

This study explores the role voice microblogging-based activities play in developing learners' spoken production skills. The study involved 33 low-intermediate level university students majoring in English at a private university in Japan. The voice microblogging application used in the study was Bubbly, a cross-platform social networking…

Hairy root biotechnology of Rauwolfia serpentina: a potent approach for the production of pharmaceutically important terpenoid indole alkaloids.

PubMed

Mehrotra, Shakti; Goel, Manoj K; Srivastava, Vikas; Rahman, Laiq Ur

2015-02-01

Hairy root cultures of Rauwolfia serpentina induced by Agrobacterium rhizogenes have been investigated extensively for the production of terpenoid indole alkaloids. Various biotechnological developments, such as scaling up in bioreactors, pathway engineering etc., have been explored to improve their metabolite production potential. These hairy roots are competent for regenerating into complete plants and show survival and unaltered biosynthetic potential during storage at low temperature. This review provides a comprehensive account of the hairy root cultures of R. serpentina, their biosynthetic potential and various biotechnological methods used to explore the production of pharmaceutically important terpenoid indole alkaloids. The review also indicates how biotechnological endeavors might improve the future progress of research for production of alkaloids using Rauwolfia hairy roots.

No vintage year ahead, but it will be better than '89

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garb, F.A.

1989-12-01

Activities in the upstream petroleum industry react to prices received for hydrocarbons and related products. Prices, in turn, are the result of supply, demand, politics and emotions. The author presents a forecast of 1990 oil industry activities and reviews the status of the pressures establishing oil and gas. According to this analysis, 1990 should be the first of a series of transition years. Oil and gas prices should be more stable than in the past. It will not be good drilling year, but will not be as bad as 1989. Gas exploration will again dominate exploration drilling. Development drilling willmore » account for more wells, if not for more budget dollars than exploration, with horizontal drilling developments being monitored closely industry-wide. Consolidation of mature producing properties into independent oil companies will continue. Decline in domestic production and an increase in hydrocarbon use and in imports should continue.« less

Design, fabrication, and integration testing of the Garden Banks 388 subsea production template

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ledbetter, W.R.; Smith, D.W.; Pierce, D.M.

1995-12-31

Enserch Exploration`s Garden Banks 388 development has a production scheme based around a floating drilling and production facility and subsea drilling/production template. The Floating Production Facility (FPF) is a converted semisubmersible drilling rig that will drill and produce through a 24-well slot subsea template. This development is located in Block 388 of the Garden Banks area in the Gulf of Mexico approximately 200 miles southwest of New Orleans, Louisiana. The production system is being installed in an area of known oil and gas reserves and will produce to a shallow water platform 54 miles away at Eugene Island 315. Themore » FPF will be permanently moored above the template. The subsea template has been installed in 2190 feet of water and will produce through a 2,000 foot free-standing production riser system to the FPF. The produced fluids are partially separated on the FPF before oil and gas are pumped through the template to export gathering lines that are connected to the shallow water facility. The system designed through-put is 40,000 BOPD of oil and 120 MMSCFD of gas.« less

Exploration for fractured petroleum reservoirs using radar/Landsat merge combinations

NASA Technical Reports Server (NTRS)

Macdonald, H.; Waite, W.; Borengasser, M.; Tolman, D.; Elachi, C.

1981-01-01

Since fractures are commonly propagated upward and reflected at the earth's surface as subtle linears, detection of these surface features is extremely important in many phases of petroleum exploration and development. To document the usefulness of microwave analysis for petroleum exploration, the Arkansas part of the Arkoma basin is selected as a prime test site. The research plan involves comparing the aircraft microwave imagery and Landsat imagery in an area where significant subsurface borehole geophysical data are available. In the northern Arkoma basin, a positive correlation between the number of linears in a given area and production from cherty carbonate strata is found. In the southern part of the basin, little relationship is discernible between surface structure and gas production, and no correlation is found between gas productivity and linear proximity or linear density as determined from remote sensor data.

Exploiting mAb structure characteristics for a directed QbD implementation in early process development.

PubMed

Karlberg, Micael; von Stosch, Moritz; Glassey, Jarka

2018-03-07

In today's biopharmaceutical industries, the lead time to develop and produce a new monoclonal antibody takes years before it can be launched commercially. The reasons lie in the complexity of the monoclonal antibodies and the need for high product quality to ensure clinical safety which has a significant impact on the process development time. Frameworks such as quality by design are becoming widely used by the pharmaceutical industries as they introduce a systematic approach for building quality into the product. However, full implementation of quality by design has still not been achieved due to attrition mainly from limited risk assessment of product properties as well as the large number of process factors affecting product quality that needs to be investigated during the process development. This has introduced a need for better methods and tools that can be used for early risk assessment and predictions of critical product properties and process factors to enhance process development and reduce costs. In this review, we investigate how the quantitative structure-activity relationships framework can be applied to an existing process development framework such as quality by design in order to increase product understanding based on the protein structure of monoclonal antibodies. Compared to quality by design, where the effect of process parameters on the drug product are explored, quantitative structure-activity relationships gives a reversed perspective which investigates how the protein structure can affect the performance in different unit operations. This provides valuable information that can be used during the early process development of new drug products where limited process understanding is available. Thus, quantitative structure-activity relationships methodology is explored and explained in detail and we investigate the means of directly linking the structural properties of monoclonal antibodies to process data. The resulting information as a decision tool can help to enhance the risk assessment to better aid process development and thereby overcome some of the limitations and challenges present in QbD implementation today.

Enabling Sustainable Exploration through the Commercial Development of Space

NASA Technical Reports Server (NTRS)

Nall, Mark; Casas, Joseph

2003-01-01

The commercial development of space offers enabling benefits to space exploration. This paper examines how those benefits can be realized, and how the Space Product Development Office of the National Aeronautics and Space Administration is taking the first steps towards opening the space frontier through vital and sustainable industrial development. The Space Product Development Office manages 15 Commercial Space Centers that partner with US industry to develop opportunities for commerce in space. This partnership directly benefits NASA exploration in four primary ways. First, by actively involving traditional and non-traditional companies in commercial space activities, it seeks and encourages to the maximum extent possible the fullest commercial use of space, as directed by NASA's charter. Second, the commercial research and technologies pursued and developed in the program often have direct applicability to NASA priority mission areas. This dual use strategy for research and technology has the potential to greatly expand what the NASA scientific community can do. Third, the commercial experiment hardware developed by the Commercial Space Centers and their industrial partners is available for use by NASA researchers in support of priority NASA research. By utilizing low cost and existing commercial hardware, essential NASA research can be more readily accomplished. Fourth, by assisting industry in understanding the use of the environment of space and in helping industry enhance the tools and technologies for NASA and commercial space systems, the market for commercial space utilization and the capability for meeting the future growing market needs is being developed. These two activities taken together form the beginning of a new space economy that will enable sustainable NASA exploration of the universe.

Taxation, depletion, and welfare: A simulation study of the US petroleum resource

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deacon, R.T.

1993-03-01

Exhaustible resources in the United States are subject to taxes on property value, production, and corporate income. As applied in practice each tax can cause high-grading - the elimination of incentives to explore, develop, and produce marginal resources - and each can tilt the time path of production toward the present or the future. The potential for such tax-induced distortions has been shown in the theoretical literature. Due to the dynamic nature of resource exploitation and the resulting complexity of models developed to study it, however, purely theoretical exercises have been unable to provide detailed results of a sort thatmore » could help guide tax policy. The present paper develops a simulation model of the US petroleum resource and uses it to study the effects of taxation on exploration and production. The model is partial equilibrium in scope and views the industry as a present value maximizing representative firm. Given expectations on the future time path of price, and a function that relates reserve additions to exploratory effort, the industry chooses time paths for exploration and production. Parameters of relevant functions are estimated with data for US petroleum operations in the onshore region of the lower 48 states. The simulated outcomes indicate that property and production (severance) taxes cause substantial deadweight losses, a tax on corporate income from extraction imposes a very small deadweight loss, and the property tax significantly biases utilization of the resource away from the future and toward the present. 33 refs., 6 figs., 3 tabs.« less

Pyranone natural products as inspirations for catalytic reaction discovery and development.

PubMed

McDonald, Benjamin R; Scheidt, Karl A

2015-04-21

Natural products continue to provide a wealth of opportunities in the areas of chemical and therapeutic development. These structures are effective measuring sticks for the current state of chemical synthesis as a field and constantly inspire new approaches and strategies. Tetrahydropryans and tetrahydropyran-4-ones are found in numerous bioactive marine natural products and medicinal compounds. Our interest in exploring the therapeutic potential of natural products containing these motifs provided the impetus to explore new methods to access highly functionalized, chiral pyran molecules in the most direct and rapid fashion possible. This goal led to exploration and development of a Lewis acid-mediated Prins reaction between a chiral β-hydroxy-dioxinone and aldehyde to produce a pyran-dioxinone fused product that can be processed in a single pot operation to the desired tetrahydropyran-4-ones in excellent yield and stereoselectivity. Although the Prins reaction is a commonly employed approach toward pyrans, this method uniquely provides a 3-carboxy-trisubstituted pyran and utilizes dioxinones in a manner that was underexplored at the time. The 3-carboxy substituent served as a key synthetic handhold when this method was applied to the synthesis of highly functionalized pyrans within the macrocyclic natural products neopeltolide, okilactiomycin, and exiguolide. When employed in challenging macrocyclizations, this tetrahydropyranone forming reaction proved highly stereoselective and robust. Another major thrust in our lab has been the synthesis of benzopyranone natural products, specifically flavonoids, because this broad and diverse family of compounds possesses an equally broad range of biological and medicinal applications. With the goal of developing a broad platform toward the synthesis of enantioenriched flavonoid analogs and natural products, a biomimetic, asymmetric catalytic approach toward the synthesis of 2-aryl benzopyranones was developed. A bifunctional hydrogen bonding/Brønstead base catalyst was ultimately found to enable this transformation in analogous manner to the biosynthesis via the enzyme chalcone isomerase. Employing thiourea catalysts derived from the pseudoenantiomeric quinine and quinidine, alkylidene β-ketoesters can be isomerized to 3-carboxy flavanones and decarboxylated in a single pot operation to stereodivergently provide highly enantioenriched flavanones in excellent yield. This method was applied to the synthesis of the abyssinone family of natural products, as well as the rotenoid, deguelin. An analogous method to isomerize chalcones was developed and applied to the synthesis of isosilybin A. In both of these related endeavors, the need for novel enabling methodologies toward the efficient creation of targeted molecular complexity drove the discovery, development and deployment of these stereoselective catalytic transformations.

Geothermal Exploration Cost and Time

DOE Data Explorer

Jenne, Scott

2013-02-13

The Department of Energy’s Geothermal Technology Office (GTO) provides RD&D funding for geothermal exploration technologies with the goal of lowering the risks and costs of geothermal development and exploration. The National Renewable Energy Laboratory (NREL) was tasked with developing a metric in 2012 to measure the impacts of this RD&D funding on the cost and time required for exploration activities. The development of this cost and time metric included collecting cost and time data for exploration techniques, creating a baseline suite of exploration techniques to which future exploration cost and time improvements can be compared, and developing an online tool for graphically showing potential project impacts (all available at http://en.openei.org/wiki/Gateway: Geothermal). This paper describes the methodology used to define the baseline exploration suite of techniques (baseline), as well as the approach that was used to create the cost and time data set that populates the baseline. The resulting product, an online tool for measuring impact, and the aggregated cost and time data are available on the Open Energy Information website (OpenEI, http://en.openei.org) for public access. - Published 01/01/2013 by US National Renewable Energy Laboratory NREL.

L1 Use and Morphosyntactic Development in the Oral Production of EFL Learners in a CLIL Context

ERIC Educational Resources Information Center

Lazaro, Amparo; Garcia Mayo, Maria del Pilar

2012-01-01

This paper explores the effects of Content and Language Integrated Learning (CLIL) instruction on the oral production of 15 high-school learners of English. The learners' use of the L1s (Basque and Spanish) in discourse markers and repair sequences as well as the learners' overall morphosyntactic development were analysed at two testing times (age…

The Production of Finite and Nonfinite Complement Clauses by Children with Specific Language Impairment and Their Typically Developing Peers

ERIC Educational Resources Information Center

Owen, Amanda J.; Leonard, Laurence B.

2006-01-01

The purpose of this study was to explore whether 13 children with specific language impairment (SLI; ages 5;1-8;0 [years;months]) were as proficient as typically developing age- and vocabulary-matched children in the production of finite and nonfinite complement clauses. Preschool children with SLI have marked difficulties with verb-related…

Knowledge work productivity effect on quality of knowledge work in software development process in SME

NASA Astrophysics Data System (ADS)

Yusoff, Mohd Zairol; Mahmuddin, Massudi; Ahmad, Mazida

2016-08-01

Knowledge and skill are necessary to develop the capability of knowledge workers. However, there is very little understanding of what the necessary knowledge work (KW) is, and how they influence the quality of knowledge work or knowledge work productivity (KWP) in software development process, including that in small and medium-sized (SME) enterprise. The SME constitutes a major part of the economy and it has been relatively unsuccessful in developing KWP. Accordingly, this paper seeks to explore the influencing dimensions of KWP that effect on the quality of KW in SME environment. First, based on the analysis of the existing literatures, the key characteristics of KW productivity are defined. Second, the conceptual model is proposed, which explores the dimensions of the KWP and its quality. This study analyses data collected from 150 respondents (based on [1], who involve in SME in Malaysia and validates the models by using structural equation modeling (SEM). The results provide an analysis of the effect of KWP on the quality of KW and business success, and have a significant relevance for both research and practice in the SME

Bringing Planetary Data into Learning Environments: A Community Effort

NASA Astrophysics Data System (ADS)

Shipp, S.; Higbie, M.; Lowes, L.

2005-12-01

Recognizing the need to communicate scientific findings, and the power of using real planetary data in educational settings to engage students in Earth and space science in meaningful ways, the South Central Organization of Researchers and Educators and the Solar System Exploration Education Forum, part of NASA's Science Mission Directorate's Support Network, have established the Planetary Data in Education (PDE) Initiative. The Initiative strives to: 1) Establish a collaborative community of educators, education specialists, curriculum developers, tool developers, learning technologists, scientists, and data providers to design and develop educationally appropriate products; 2) Build awareness in the broader educational and scientific community of existing programs, products, and resources; 3) Address issues hindering the effective use of planetary data in formal and informal educational settings; and 4) Encourage partnerships that leverage the community's expertise The PDE community has hosted two conferences exploring issues in using data in educational settings. The community recognizes that data are available through venues such as the Planetary Data Systems (PDS), but not in a format that the end-user in a formal or informal educational setting can digest; these data are intended for the scientific audience. Development of meaningful educational programs using planetary data requires design of appropriate learner interfaces and involvement of data providers, product developers, learning technologists, scientists, and educators. The PDE community will participate in the development of Earth Exploration Toolbooks during the DLESE Data Services Workshop and will host a workshop in the summer of 2006 to bring together small groups of educators, data providers, and learning technologists, and scientists to design and develop products that bring planetary data into educational settings. In addition, the PDE community hosts a Web site that presents elements identified as needed by the community, including examples of planetary data use in education, recommendations for program development, links to data providers, opportunities for collaboration, pertinent research, and a Web portal to access educational resources using planetary data on the DLESE Web site.

Factors that influence children's gambling attitudes and consumption intentions: lessons for gambling harm prevention research, policies and advocacy strategies.

PubMed

Pitt, Hannah; Thomas, Samantha L; Bestman, Amy; Daube, Mike; Derevensky, Jeffrey

2017-02-17

Harmful gambling is a public health issue that affects not only adults but also children. With the development of a range of new gambling products, and the marketing for these products, children are potentially exposed to gambling more than ever before. While there have been many calls to develop strategies which protect children from harmful gambling products, very little is known about the factors that may influence children's attitudes towards these products. This study aimed to explore children's gambling attitudes and consumption intentions and the range of consumer socialisation factors that may influence these attitudes and behaviours. Children aged 8 to 16 years old (n = 48) were interviewed in Melbourne, Australia. A semi-structured interview format included activities with children and open-ended questions. We explored children's perceptions of the popularity of different gambling products, their current engagement with gambling, and their future gambling consumption intentions. We used thematic analysis to explore children's narratives with a focus on the range of socialising factors that may shape children's gambling attitudes and perceptions. Three key themes emerged from the data. First, children's perceptions of the popularity of different products were shaped by what they had seen or heard about these products, whether through family activities, the media (and in particular marketing) of gambling products, and/or the alignment of gambling products with sport. Second, children's gambling behaviours were influenced by family members and culturally valued events. Third, many children indicated consumption intentions towards sports betting. This was due to four key factors: (1) the alignment of gambling with culturally valued activities; (2) their perceived knowledge about sport; (3) the marketing and advertising of gambling products (and in particular sports betting); and (4) the influence of friends and family. This study indicates that there is a range of socialisation factors, particularly family and the media (predominantly via marketing), which may be positively shaping children's gambling attitudes, behaviours and consumption intentions. There is a need for governments to develop effective policies and regulations to reduce children's exposure to gambling products and ensure they are protected from the harms associated with gambling.

The German collaborative project SUGAR Utilization of a natural treasure - Developing innovative techniques for the exploration and production of natural gas from hydrate-bearing sediments

NASA Astrophysics Data System (ADS)

Haeckel, M.; Bialas, J.; Wallmann, K. J.

2009-12-01

Gas hydrates occur in nature at all active and passive continental margins as well as in permafrost regions, and vast amounts of natural gas are bound in those deposits. Geologists estimate that twice as much carbon is bound in gas hydrates than in any other fossil fuel reservoir, such as gas, oil and coal. Hence, natural gas hydrates represent a huge potential energy resource that, in addition, could be utilized in a CO2-neutral and therefore environmentally friendly manner. However, the utilization of this natural treasure is not as easy as the conventional production of oil or natural gas and calls for new and innovative techniques. In the framework of the large-scale collaborative research project SUGAR (Submarine Deposits of Gas Hydrates - Exploration, Production and Transportation), we aim to produce gas from methane hydrates and to sequester carbon dioxide from power plants and other industrial sources as CO2 hydrates in the same host sediments. Thus, the SUGAR project addresses two of the most pressing and challenging topics of our time: development of alternative energy strategies and greenhouse gas mitigation techniques. The SUGAR project is funded by two federal German ministries and the German industry for an initial period of three years. In the framework of this project new technologies starting from gas hydrate exploration techniques over drilling technologies and innovative gas production methods to CO2 storage in gas hydrates and gas transportation technologies will be developed and tested. Beside the performance of experiments, numerical simulation studies will generate data regarding the methane production and CO2 sequestration in the natural environment. Reservoir modelling with respect to gas hydrate formation and development of migration pathways complete the project. This contribution will give detailed information about the planned project parts and first results with focus on the production methods.

Collaborative Computer Graphics Product Development between Academia and Government: A Dynamic Model

NASA Technical Reports Server (NTRS)

Fowler, Deborah R.; Kostis, Helen-Nicole

2016-01-01

Collaborations and partnerships between academia and government agencies are common, especially when it comes to research and development in the fields of science, engineering and technology. However, collaboration between a government agency and an art school is rather atypical. This paper presents the Collaborative Student Project, which aims to explore the following challenge: The ideation, development and realization of education and public outreach products for NASAs upcoming ICESat-2 mission in collaboration with art students.

Bacterial and Fungal Proteolytic Enzymes: Production, Catalysis and Potential Applications.

PubMed

da Silva, Ronivaldo Rodrigues

2017-09-01

Submerged and solid-state bioprocesses have been extensively explored worldwide and employed in a number of important studies dealing with microbial cultivation for the production of enzymes. The development of these production technologies has facilitated the generation of new enzyme-based products with applications in pharmaceuticals, food, bioactive peptides, and basic research studies, among others. The applicability of microorganisms in biotechnology is potentiated because of their various advantages, including large-scale production, short time of cultivation, and ease of handling. Currently, several studies are being conducted to search for new microbial peptidases with peculiar biochemical properties for industrial applications. Bioprospecting, being an important prerequisite for research and biotechnological development, is based on exploring the microbial diversity for enzyme production. Limited information is available on the production of specific proteolytic enzymes from bacterial and fungal species, especially on the subgroups threonine and glutamic peptidases, and the seventh catalytic type, nonhydrolytic asparagine peptide lyase. This gap in information motivated the present study about these unique biocatalysts. In this study, the biochemical and biotechnological aspects of the seven catalytic types of proteolytic enzymes, namely aspartyl, cysteine, serine, metallo, glutamic, and threonine peptidase, and asparagine peptide lyase, are summarized, with an emphasis on new studies, production, catalysis, and application of these enzymes.

From Big Data to Small Transportable Products for Decision Support for Floods in Namibia

NASA Astrophysics Data System (ADS)

Mandl, D.; Frye, S.; Cappelaere, P.; Policelli, F.; Handy, M.; Sohlberg, R. A.; Grossman, R.

2013-12-01

During the past four years, a team from NASA, Oklahoma University, University of Maryland and University of Chicago in collaboration with the Namibia Hydrological Services (NHS) has explored ways to provide decision support products for floods. The products include a variety of data including a hydrological model, ground measurements such as river gauges, and earth remote sensing data. This poster or presentation highlights the lessons learned in acquiring, storing, managing big data on the cloud and turning it into relevant products for GEOSS users. Technology that has been explored includes the use of Hadoop/MapReduce and Accumulo to process and manage the large data sets. OpenStreetMap was explored for use in cataloging water boundaries and enabling collaborative mapping of the base water mask and floods. A Flood Dashboard was created to customize displays of various data products. Finally, a higher level Geo-Social Application Processing Interface (API) was developed so that users can discover, generate products dynamically for their specific needs/societal benefit areas and then share them with their Community of Practice over social networks. Results of this experiment have included 100x reduction in size of some flood products, making it possible to distribute these products to mobile platforms and/or bandwidth-limited users.

Strategy for exploration of the outer planets: 1986-1996

NASA Technical Reports Server (NTRS)

1986-01-01

Over the past decade COMPLEX has published three strategy reports which, taken together, encompass the entire planetary system and recommend a coherent program of planetary exploration. The highest priority for outer planet exploration during the next decade is intensive study of Saturn (the planet, satellites, rings, and magnetosphere) as a system. The Committee additionally recommends that NASA engage in the following supporting activities: increased support of laboratory and theoretical studies; pursuit of earth-based and earth-orbital observations; commitment to continued operation of productive spacecraft; implementation of the instrument development plan as appropriate for the outer solar system; studies of deep atmospheric probes; development of penetrators or other hard landers; development of radiation-hardened spacecraft; and development of low-thrust propulsion systems. Longer-term objectives include exploration and intensive study of: the Uranus and Neptune systems; planetology of the Galilean satellites and Titan; and the inner Jovian system.

Exploring the Validity of a Second Language Intercultural Pragmatics Assessment Tool

ERIC Educational Resources Information Center

Timpe-Laughlin, Veronika; Choi, Ikkyu

2017-01-01

Pragmatics has been a key component of language competence frameworks. While the majority of second/foreign language (L2) pragmatics tests have targeted productive skills, the assessment of receptive pragmatic skills remains a developing field. This study explores validation evidence for a test of receptive L2 pragmatic ability called the American…

Using space resources

NASA Technical Reports Server (NTRS)

Sullivan, Thomas A.; Mckay, David S.

1991-01-01

The topics covered include the following: reducing the cost of space exploration; the high cost of shipping; lunar raw materials; some useful space products; energy from the moon; ceramic, glass, and concrete construction materials; mars atmosphere resources; relationship to the Space Exploration Initiative (SEI); an evolutionary approach to using space resources; technology development; and oxygen and metal coproduction.

Understanding Co-Development of Conceptual and Epistemic Understanding through Modeling Practices with Mobile Internet

ERIC Educational Resources Information Center

Ryu, Suna; Han, Yuhwha; Paik, Seoung-Hey

2015-01-01

The present study explores how engaging in modeling practice, along with argumentation, leverages students' epistemic and conceptual understanding in an afterschool science/math class of 16 tenth graders. The study also explores how students used mobile Internet phones (smart phones) productively to support modeling practices. As the modeling…

Development and Demonstration of Sustainable Surface Infrastructure for Moon/Mars Exploration

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.; Larson, William E.; Picard, Martin

2011-01-01

For long-term human exploration of the Moon and Mars to be practical, affordable, and sustainable, future missions must be able to identify and utilize resources at the site of exploration. The ability to characterize, extract, processes, and separate products from local material, known as In-Situ Resource Utilization (ISRU), can provide significant reductions in launch mass, logistics, and development costs while reducing risk through increased mission flexibility and protection as well as increased mission capabilities in the areas of power and transportation. Making mission critical consumables like propellants, fuel cell reagents and life support gases, as well as in-situ crew/hardware protection and energy storage capabilities can significantly enhance robotic and human science and exploration missions, however other mission systems need to be designed to interface with and utilize these in-situ developed products and services from the start or the benefits will be minimized or eliminated. This requires a level of surface and transportation system development coordination not typically utilized during early technology and system development activities. An approach being utilized by the US National Aeronautics and Space Administration and the Canadian Space Agency has been to utilize joint analogue field demonstrations to focus technology development activities to demonstrate and integrate new and potentially game changing. mission critical capabilities that would enable an affordable and sustainable surface infrastructure for lunar and Mars robotic and human exploration. Two analogue field tests performed in November 2008 and February 2010 demonstrated first generation capabilities for lunar resource prospecting, exploration site preparation, and oxygen extraction from regolith while initiating integration with mobility, science, fuel cell power, and propulsion disciplines. A third analogue field test currently planned for June 2012 will continue and expand the fidelity and integration of these surface exploration and infrastructure capabilities while adding Mars exploration technologies, improving remote operations and control of hardware, and promoting the use of common software, interfaces, & standards for control and operation for surface exploration and science. The next field test will also attempt to include greater involvement by industry, academia, and other countries/space agencies. This paper will provide an overview of the development and demonstration approach utilized to date, the results of the previous two ISRU-focused field analogue tests in Hawaii, and the current objectives and plans for the 3rd international Hawaii analogue field test.

Dynamics of Aviation Biofuel Investment, Incentives, and Market Growth: An Exploration Using the Biomass Scenario Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vimmerstedt, Laura; Newes, Emily

The Federal Aviation Administration promotes the development of an aviation biofuel market, and has pursued a goal of 1 billion gallons of production annually by 2018. Although this goal is unlikely to be met, this analysis applies the Biomass Scenario Model to explore conditions affecting market growth, and identifies policy incentive and oil price conditions under which this level of production might occur, and by what year. Numerous combinations of conditions that are more favorable than current conditions can reach the goal before 2030.

Aeronautics and Space Report of the President: Fiscal Year 2009 Activities

NASA Technical Reports Server (NTRS)

2009-01-01

In fiscal year 2009 (FY 09), the Exploration Systems Mission Directorate's (ESMD) Advanced Capabilities Division (ACD) provided critical research and technology products that reduced operational and technical risks for the flight systems being developed by the Constellation Program.1 These products addressed high-priority technology requirements for lunar exploration; risk mitigation related to astronaut health and performance; basic research in life and physical sciences using the International Space Station (ISS), free-flying spacecraft, and ground-based laboratories; and lunar robotic missions to gather data relevant to future human lunar missions.

Development of a strategic model for integrating complementary medicines into professional pharmacy practice.

PubMed

Ung, Carolina Oi Lam; Harnett, Joanna; Hu, Hao

2017-08-03

Traditional medicine (TM) and complementary medicine (CM) products have played an increasingly important role in the business of pharmacy for over two decades in a number of countries. With a focus on the quality use of all medicines including complementary medicines, there have been a number of initiatives to encourage the integration of TM/CM products into professional practice. Recent studies report that many of the barriers that prevent such integration remain. To explore the pharmacists' perspective regarding how barriers to the integration of TM/CM products into the professional practice of pharmacy could be resolved. Purposive sampling and snowballing were used to recruit 11 registered pharmacists who had worked in community pharmacy for a minimum of 6 months to participate in one of 3 focus groups. Focus group questions informed by previous studies, explored participants' perspectives on the actions required to support professional services related to TM/CM products. Pharmacists proposed that five key stakeholders (professional pharmacy organizations, universities, government, pharmacy owners, and pharmacists) enact 4 developments that require a collaborative effort ("education and training", "building the evidence base", "developing reliable and accessible information resources", and "workplace support for best practice"). Manufacturers of TM/CM products were not identified by pharmacists as collaborators in these developments. Collectively, the findings from this study support a strategic model to guide the integration of TM/CM products into the professional practice of pharmacy. Copyright © 2017 Elsevier Inc. All rights reserved.

Oil and gas developments in South Africa, Central America, Caribbean Area, and Mexico in 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tappmeyer, D.M.

1985-10-01

For the 25 countries described in the region, exploration activity continued to be centered in proven petroleum provinces in 1984. Exploration activity increased in Brazil, Colombia, and Venezuela. Important, successful exploration efforts continued in areas around Cano Limon field in Colombia, and Guafita and La Victoria fields in Venezuela. Notable discoveries in South America included the 42-46-1X San Martin Cretaceous discovery by Shell in the Ucayali basin in Peru, the significant oil and gas discovery at Palmar Largo ES-1 by YPF in Argentina, and the first offshore gas discovery, the Pecten 1-SPS-20 wildcat in the Santo basin in Brazil. Oilmore » production increased in Barbados, Brazil, Colombia, Ecuador, Mexico, Peru, Trinidad and Tobago, and Venezuela. A notable increase (40%) in oil production occurred in Brazil. Gas production increased in Argentina, Barbados, Colombia, Peru, and Trinidad and Tobago. 8 figures, 8 tables.« less

Oil and gas developments in South America, Central America, Caribbean Area, and Mexico in 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tappmeyer, D.M.

1985-10-01

For the 25 countries described in the region, exploration activity continued to be centered in proven petroleum provinces in 1984. Exploration activity increased in Brazil, Colombia, and Venezuela. Important, successful exploration efforts continued in areas around Cano Limon field in Colombia, and Guafita and La Victoria fields in Venezuela. Notable discoveries in South America included the 42-461X San Martin Cretaceous discovery by Shell in the Ucayali basin in Peru, the significant oil and gas discovery at Palmar Largo ES-1 by YPF in Argentina, and the first offshore gas discovery, the Pecten 1-SPS-20 wildcat in the Santo basin in Brazil. Oilmore » production increased in Barbados, Brazil, Colombia, Ecuador, Mexico, Peru, Trinidad and Tobago, and Venezuela. A notable increase (40%) in oil production occurred in Brazil. Gas production increased in Argentina, Barbados, Colombia, Peru, and Trinidad and Tobago.« less

Record development expected in Indonesia and Malaysia. [Extensive survey of oil and gas developments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-08-15

Crude production from the countries of Indonesia, Australia, Brunei, Malaysia, and New Zealand averaged 2,043,866 bpd in 1974, a 1.2 percent decrease from 1973 average rates. Several new fields in Kalimantan, Java, and Sumatra were put onstream, and the prolific new 100,000-bpd Walio field in Irian Jaya was tapped. Australian crude production, primarily from Bass Strait fields, slipped to 386,127 bpd. The Australian government told of plans for the country's huge natural gas potential and a preliminary schedule was proposed for a multi-billion-dollar North West Shelf program involving Woodside-Burmah. In Brunei, Shell continued development of new offshore fields; but crudemore » production dropped to 192,708 bpd in 1974, from 229,277 bpd in 1973. Emphasis was on adding gas wells to the big Southwest Ampa offshore field; gas production increased last year to an estimated 500 MMcfd. At the start of 1975-before politics interfered-Malaysia was headed for a significant production increase. New Zealand intensified exploration with addition of the Penrod 74 semi-submersible, and a 400-foot, 12-well platform is under construction for the huge Maui gas field. Papua New Guinea is slowly approaching independence from Australia and exploration increased in the Gulf of Papua around Phillips' earlier gas discoveries.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

New fields are being added even while recent finds are brought on using floating production systems and gas pipelines. Intensive workover/redrilling continues in older onshore provinces. The paper discusses exploration, development, drilling and production in China, Indonesia, India, Malaysia, Thailand, Viet Nam, Pakistan, Myanmar, Brunei, and the Philippines, Cambodia, Bangladesh, Japan, Mongolia, and Taiwan are briefly mentioned.

Education, Productivity and Inequality: The East African Natural Experiment.

ERIC Educational Resources Information Center

Knight, John B.; Sabot, Richard H.

The relationship between resources devoted to education and the economy of developing nations is explored. The research seeks to understand if and how investment in education translates into increased economic growth and labor productivity. Additionally, the function of education in reducing various dimensions of economic inequality is examined.…

International Oil and Gas Exploration and Development

EIA Publications

1993-01-01

Presents country level data on oil reserves, oil production, active drilling rigs, seismic crews, wells drilled, oil reserve additions, and oil reserve to production ratios (R/P ratios) for about 85 countries, where available, from 1970 through 1991. World and regional summaries are given in both tabular and graphical form.

Biosurfactants' Production from Renewable Natural Resources: Example of Innovativeand Smart Technology in Circular Bioeconomy

NASA Astrophysics Data System (ADS)

Satpute, Surekha K.; Płaza, Grażyna A.; Banpurkar, Arun G.

2017-03-01

A strong developed bio-based industrial sector will significantly reduce dependency on fossil resources, help the countries meet climate change targets, and lead to greener and more environmental friendly growth. The key is to develop new technologies to sustainably transform renewable natural resources into bio-based products and biofuels. Biomass is a valuable resource and many parameters need to be taken in to account when assessing its use and the products made from its. The bioeconomy encompass the production of renewable biological resources and their conversion into food, feed and bio-based products (chemicals, materials and fuels) via innovative and efficient technologies provided by industrial biotechnology. The paper presents the smart and efficient way to use the agro-industrial, dairy and food processing wastes for biosurfactant's production. Clarification processes are mandatory to use the raw substrates for microbial growth as well as biosurfactant production for commercial purposes. At the same time it is very essential to retain the nutritional values of those cheap substrates. Broad industrial perspectives can be achieved when quality as well as the quantity of the biosurfactant is considered in great depth. Since substrates resulting from food processing, dairy, animal fat industries are not explored in great details; and hence are potential areas which can be explored thoroughly.

30 CFR 250.202 - What criteria must the Exploration Plan (EP), Development and Production Plan (DPP), or...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What criteria must the Exploration Plan (EP... Section 250.202 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND... stipulations, and other Federal laws; (b) Is safe; (c) Conforms to sound conservation practices and protects...

An Exploration of the Aesthetics of an Oral History Performance Developed in the Classroom

ERIC Educational Resources Information Center

Wang, Wan-Jung

2010-01-01

This paper aims to explore a range of aesthetic aspects involved in the devising and production processes of oral history performance in a classroom setting. It touches upon the ethical dimension of aesthetics employing the Confucianist Wang Yang Ming's aesthetic philosophy and Buber's theories of relation as the theoretical frames. The devising…

Building Workforce Strength: Creating Value through Workforce and Career Development

ERIC Educational Resources Information Center

Elsdon, Ron

2010-01-01

This book explores the perspectives of experienced practitioners, sharing ideas about building and sustaining organizational strength through workforce development practices and systems. As the saying goes, a company's greatest resource is its people. When managers really believe that and work to develop organizational capabilities, productivity,…

Microcomputer Applications for Library Instruction: Automation of Test and Assignment Scoring, and Student Record Keeping.

ERIC Educational Resources Information Center

Sugranes, Maria R.; Snider, Larry C.

1985-01-01

Describes the development of an automated library instruction records management system using microcomputer technology. Development described includes assessment of need, exploration of options, system design, and operational development. System products are identified and operational results are reported based on actual system performance.…

Quality and safety aspects of meat products as affected by various physical manipulations of packaging materials.

PubMed

Lee, Keun Taik

2010-09-01

This article explores the effects of physically manipulated packaging materials on the quality and safety of meat products. Recently, innovative measures for improving quality and extending the shelf-life of packaged meat products have been developed, utilizing technologies including barrier film, active packaging, nanotechnology, microperforation, irradiation, plasma and far-infrared ray (FIR) treatments. Despite these developments, each technology has peculiar drawbacks which will need to be addressed by meat scientists in the future. To develop successful meat packaging systems, key product characteristics affecting stability, environmental conditions during storage until consumption, and consumers' packaging expectations must all be taken into consideration. Furthermore, the safety issues related to packaging materials must also be taken into account when processing, packaging and storing meat products.

Advanced program development management software system. Software description and user's manual

NASA Technical Reports Server (NTRS)

1990-01-01

The objectives of this project were to apply emerging techniques and tools from the computer science discipline of paperless management to the activities of the Space Transportation and Exploration Office (PT01) in Marshall Space Flight Center (MSFC) Program Development, thereby enhancing the productivity of the workforce, the quality of the data products, and the collection, dissemination, and storage of information. The approach used to accomplish the objectives emphasized the utilization of finished form (off-the-shelf) software products to the greatest extent possible without impacting the performance of the end product, to pursue developments when necessary in the rapid prototyping environment to provide a mechanism for frequent feedback from the users, and to provide a full range of user support functions during the development process to promote testing of the software.

The proliferation of aerospace weapons technology: Ballistic missiles and the case of Brazil

NASA Astrophysics Data System (ADS)

Vossen, Terrence John

1993-04-01

The rationale behind the development of ballistic missile production in Brazil is examined by exploring the political, military, and economic determinants of ballistic missile demand in that country. To ascertain how Brazil developed missile production capabilities, the contributions of aerospace industries in industrialized states, the Brazilian space program, trade between less-developed countries, and illicit trade in missile technology are assessed. It is argued that missile development increasingly became a function of economic as opposed to security considerations, and that technologies transferred from developed country aerospace firms and Brazil's space program were primarily responsible for the creation of production capabilities. It is also contended that the proliferation of missile technology to Brazil was consistent with the workings of a system evident in the aerospace weapons technology market that sustains the horizontal spread of weapons production capabilities.

Impacts of Climate Change on Biofuels Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melillo, Jerry M.

2014-04-30

The overall goal of this research project was to improve and use our biogeochemistry model, TEM, to simulate the effects of climate change and other environmental changes on the production of biofuel feedstocks. We used the improved version of TEM that is coupled with the economic model, EPPA, a part of MIT’s Earth System Model, to explore how alternative uses of land, including land for biofuels production, can help society meet proposed climate targets. During the course of this project, we have made refinements to TEM that include development of a more mechanistic plant module, with improved ecohydrology and considerationmore » of plant-water relations, and a more detailed treatment of soil nitrogen dynamics, especially processes that add or remove nitrogen from ecosystems. We have documented our changes to TEM and used the model to explore the effects on production in land ecosystems, including changes in biofuels production.« less

Advanced Life Support Research and Technology Development

NASA Technical Reports Server (NTRS)

Kliss, Mark

2001-01-01

A videograph outlining life support research. The Human Exploration and Development of Space (HEDS) Enterprise's goals are to provide life support self-sufficiency for human beings to carry out research and exploration productively in space, to open the door for planetary exploration, and for benefits on Earth. Topics presented include the role of NASA Ames, funding, and technical monitoring. The focused research areas discussed include air regeneration, carbon dioxide removal, Mars Life Support, water recovery, Vapor Phase Catalytic Ammonia Removal (VPCAR), solid waste treatment, and Supercritical Water Oxidation (SCWC). Focus is placed on the utilization of Systems Integration, Modeling and Analysis (SIMA) and Dynamic Systems Modeling in this research.

The Application of Architecture Frameworks to Modelling Exploration Operations Costs

NASA Technical Reports Server (NTRS)

Shishko, Robert

2006-01-01

Developments in architectural frameworks and system-of-systems thinking have provided useful constructs for systems engineering. DoDAF concepts, language, and formalisms, in particular, provide a natural way of conceptualizing an operations cost model applicable to NASA's space exploration vision. Not all DoDAF products have meaning or apply to a DoDAF inspired operations cost model, but this paper describes how such DoDAF concepts as nodes, systems, and operational activities relate to the development of a model to estimate exploration operations costs. The paper discusses the specific implementation to the Mission Operations Directorate (MOD) operational functions/activities currently being developed and presents an overview of how this powerful representation can apply to robotic space missions as well.

Developing Technology Products - A Physicist's Perspective

NASA Astrophysics Data System (ADS)

Burka, Michael

2014-03-01

There are many physicists working in the industrial sector. We rarely have the word physicist in our job title; we are far more commonly called engineers or scientists. But, we are physicists, and we succeed because our training in physics has given us the habits of mind and the technical skills that one needs to solve complex technical challenges. This talk will explore the transition from physics research to technology product development using examples from my own career, first as a postdoctoral fellow and research scientist on the LIGO project, and then developing products in the spectroscopy, telecommunications, and medical device industries. Approaches to identifying and pursuing opportunities in industry will be discussed.

From the Ground Up. [Videotape

ERIC Educational Resources Information Center

Enns, Garry; And Others

Through interviews with farmers, agricultural experts, and students, this video raises student's awareness of sustainable development issues in modern agriculture and food production. The video explores the following themes: agriculture and sustainable development, different approaches to farming, evaluation of farming practices in the context of…

Integration into What? Reflections on Development Planning for Women.

ERIC Educational Resources Information Center

Boulding, Elise

1980-01-01

Integration of women into the existing international economic and technological order promises only further loss of autonomy and increased marginalization. Women's groups should explore human-centered development which will generate new social structures and new approaches to human productivity and welfare. (SK)

Creativity and Cognition: Producing Effective Novelty.

ERIC Educational Resources Information Center

Cropley, Arthur J.

1999-01-01

Reviews cognitive processes, control mechanisms, and structures in creative thinking, and examines the way these aspects of cognition develop from childhood to adulthood. The cognitive definition of creativity, cognitive approaches to novelty production, creativity and cognitive development, and mechanisms guiding cognitive processes are explored.…

Global climate change implications for coastal and offshore oil and gas development

USGS Publications Warehouse

Burkett, V.

2011-01-01

The discussion and debate about climate change and oil and gas resource development has generally focused on how fossil fuel use affects the Earth's climate. This paper explores how the changing climate is likely to affect oil and gas operations in low-lying coastal areas and the outer continental shelf. Oil and gas production in these regions comprises a large sector of the economies of many energy producing nations. Six key climate change drivers in coastal and marine regions are characterized with respect to oil and gas development: changes in carbon dioxide levels and ocean acidity, air and water temperature, precipitation patterns, the rate of sea level rise, storm intensity, and wave regime. These key drivers have the potential to independently and cumulatively affect coastal and offshore oil and gas exploration, production, and transportation, and several impacts of climate change have already been observed in North America. ?? 2011.

The Emergence of Productive Speech and Language in Spanish-Learning Paediatric Cochlear Implant Users

ERIC Educational Resources Information Center

Moreno-Torres, Ignacio

2014-01-01

It has been proposed that cochlear implant users may develop robust categorical perception skills, but that they show limited precision in perception. This article explores if a parallel contrast is observable in production, and if, despite acquiring typical linguistic representations, their early words are inconsistent. The participants were…

Model for understanding consumer textural food choice

PubMed Central

Jeltema, Melissa; Beckley, Jacqueline; Vahalik, Jennifer

2015-01-01

The current paradigm for developing products that will match the marketing messaging is flawed because the drivers of product choice and satisfaction based on texture are misunderstood. Qualitative research across 10 years has led to the thesis explored in this research that individuals have a preferred way to manipulate food in their mouths (i.e., mouth behavior) and that this behavior is a major driver of food choice, satisfaction, and the desire to repurchase. Texture, which is currently thought to be a major driver of product choice, is a secondary factor, and is important only in that it supports the primary driver—mouth behavior. A model for mouth behavior is proposed and the qualitative research supporting the identification of different mouth behaviors is presented. The development of a trademarked typing tool for characterizing mouth behavior is described along with quantitative substantiation of the tool's ability to group individuals by mouth behavior. The use of these four groups to understand textural preferences and the implications for a variety of areas including product design and weight management are explored. PMID:25987995

Model for understanding consumer textural food choice.

PubMed

Jeltema, Melissa; Beckley, Jacqueline; Vahalik, Jennifer

2015-05-01

The current paradigm for developing products that will match the marketing messaging is flawed because the drivers of product choice and satisfaction based on texture are misunderstood. Qualitative research across 10 years has led to the thesis explored in this research that individuals have a preferred way to manipulate food in their mouths (i.e., mouth behavior) and that this behavior is a major driver of food choice, satisfaction, and the desire to repurchase. Texture, which is currently thought to be a major driver of product choice, is a secondary factor, and is important only in that it supports the primary driver-mouth behavior. A model for mouth behavior is proposed and the qualitative research supporting the identification of different mouth behaviors is presented. The development of a trademarked typing tool for characterizing mouth behavior is described along with quantitative substantiation of the tool's ability to group individuals by mouth behavior. The use of these four groups to understand textural preferences and the implications for a variety of areas including product design and weight management are explored.

Geothermal Life Cycle Calculator

DOE Data Explorer

Sullivan, John

2014-03-11

This calculator is a handy tool for interested parties to estimate two key life cycle metrics, fossil energy consumption (Etot) and greenhouse gas emission (ghgtot) ratios, for geothermal electric power production. It is based solely on data developed by Argonne National Laboratory for DOE’s Geothermal Technologies office. The calculator permits the user to explore the impact of a range of key geothermal power production parameters, including plant capacity, lifetime, capacity factor, geothermal technology, well numbers and depths, field exploration, and others on the two metrics just mentioned. Estimates of variations in the results are also available to the user.

NASA Virtual Institutes: International Bridges for Space Exploration

NASA Technical Reports Server (NTRS)

Schmidt, Gregory K.

2016-01-01

NASA created the first virtual institute, the NASA Astrobiology Institute (NAI), in 2009 with an aim toward bringing together geographically disparate and multidisciplinary teams toward the goal of answering broad questions in the then-new discipline of astrobiology. With the success of the virtual institute model, NASA then created the NASA Lunar Science Institute (NLSI) in 2008 to address questions of science and human exploration of the Moon, and then the NASA Aeronautics Research Institute (NARI) in 2012 which addresses key questions in the development of aeronautics technologies. With the broadening of NASA's human exploration targets to include Near Earth Asteroids and the moons of Mars as well as the Moon, the NLSI morphed into the Solar System Exploration Research Virtual Institute (SSERVI) in 2012. SSERVI funds domestic research teams to address broad questions at the intersection of science and human exploration, with the underlying principle that science enables human exploration, and human exploration enables science. Nine domestic teams were funded in 2014 for a five-year period to address a variety of different topics, and nine international partners (with more to come) also work with the U.S. teams on a variety of topics of mutual interest. The result is a robust and productive research infrastructure that is not only scientifically productive but can respond to strategic topics of domestic and international interest, and which develops a new generation of researchers. This is all accomplished with the aid of virtual collaboration technologies which enable scientific research at a distance. The virtual institute model is widely applicable to a range of space science and exploration problems.

Guide for studying and evaluating internal accounting controls. Oil and gas exploration, development and production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-01-01

One of the most important responsibilities of any company's management is to establish and maintain, via periodic evaluations, is adequate internal accounting controls. Arthur Andersen and Co. approaches this problem as it relates to the oil and gas industry by logically dividing the economic events that affect a given company into four groups of activity termed ''business cycles'': treasury, expenditure, conversion (exploration, development, and production), and revenue activities. Independent public accountants can evaluate a company's existing internal controls much more thoroughly by studying only one category of business transactions at a time. Arthur Andersen's guide to reviewing internal controls coversmore » each step of this ''transaction-flow'' method as applied to a typical oil and gas company.« less

The rapid bi-level exploration on the evolution of regional solar energy development

NASA Astrophysics Data System (ADS)

Guan, Qing; An, Haizhong; Li, Huajiao; Hao, Xiaoqing

2017-01-01

As one of the renewable energy, solar energy is experiencing increased but exploratory development worldwide. The positive or negative influences of regional characteristics, like economy, production capacity and allowance policies, make them have uneven solar energy development. In this paper, we aim at quickly exploring the features of provincial solar energy development, and their concerns about solar energy. We take China as a typical case, and combine text mining and two-actor networks. We find that the classification of levels based on certain nodes and the amount of degree avoids missing meaningful information that may be ignored by global level results. Moreover, eastern provinces are hot focus for the media, western countries are key to bridge the networks and special administrative region has local development features; third, most focus points are more about the application than the improvement of material. The exploration of news provides practical information to adjust researches and development strategies of solar energy. Moreover, the bi-level exploration, which can also be expanded to multi-level, is helpful for governments or researchers to grasp more targeted and precise knowledge.

Green Curriculum Analysis in Technological Education

ERIC Educational Resources Information Center

Chakraborty, Arpita; Singh, Manvendra Pratap; Roy, Mousumi

2018-01-01

With rapid industrialization and technological development, India is facing adverse affects of unsustainable pattern of production and consumption. Education for sustainable development has been widely recognized to reduce the threat of environmental degradation and resource depletion. This paper used the content analysis method to explore the…

Virtual Retail Simulations in Second Life

ERIC Educational Resources Information Center

Drake-Bridges, Erin; Strelzoff, Andrew; Sulbaran, Tulio

2011-01-01

This paper explores the use of simulations in virtual reality to teach students the fundamental processes behind retailing and product development. The project described involved one class of students who developed their own clothing lines of "virtual merchandise." A second class of students then "purchased" the wholesale…

Greider geothermal statement, based on testimony presented to Lt. Gov. Dymally Committee. [Development of geothermal industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greider, B.

Factors that contribute to the delay of geothermal development by utilities are discussed. These include: the increasingly complex regulations on the Geysers field; low quality and sizes of hot water resources; economics of financing geothermal exploration; professional experience; and lack of faith in the technology of conversion of hot water into electricity. Key issues that must be resolved before geothermal development can significantly penetrate the electricity generation industry are presented. It is pointed out that legislation to stimulate development of California's geothermal resources should be based on consideration of the following items: streamlined controls which allow geothermal exploration and developmentmore » to proceed under a minimum of effective regulation; reasonable tax provisions encouraging exploration, research, development, and production of geothermal energy; and suitable economic incentives for utility companies that will encourage early commitment to construct generating plants. (LBS)« less

Film in Development.

ERIC Educational Resources Information Center

Information Center on Instructional Technology Report, 1976

1976-01-01

The positive and negative aspects of using film as a medium for inducing change in developing nations are explored in this issue. Critics of the use of film for development cite (1) the culture specific nature of film content of foreign produced films; (2) the technical, economic, and logistical problems of in-country production; and (3) lack of…

Subsurface recognition of oolitic facies in carbonate sequence: Exploration and development applications: Ste. Genevieve Formation (Mississippian), Illinois basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bandy, W.F.

1989-08-01

The oolitic grainstone facies of the Ste. Genevieve Limestone is a widespread and highly productive reservoir in the Illinois basin. However, exploration and development of these oolitic facies are hampered by the inability to recognize the reservoir on logs. In many areas, the only log data available are old wireline electric logs. Comparison of cores with log response in northern Lawrence field, Lawrence County, Illinois, indicates a subjective but predictable relationship between log signature and carbonate lithology. Two productive lithologies, dolomite and oolitic grainstone, display well-developed SP curves. However, resistivity response is greatest in dense limestone, less well developed inmore » oolitic grainstone, and poorly developed in dolomites. On gamma-ray logs, oolitic facies can be differentiated from dolomites by their lower radioactivity. Oolitic sands are most easily recognized on porosity logs, where their average porosity is 13.7%, only half the average porosity of dolomites. In a new well, the best information for subsequent offset and development of an oolitic reservoir is provided by porosity and dipmeter logs.« less

Robotics for Human Exploration

NASA Technical Reports Server (NTRS)

Fong, Terrence; Deans, Mathew; Bualat, Maria

2013-01-01

Robots can do a variety of work to increase the productivity of human explorers. Robots can perform tasks that are tedious, highly repetitive or long-duration. Robots can perform precursor tasks, such as reconnaissance, which help prepare for future human activity. Robots can work in support of astronauts, assisting or performing tasks in parallel. Robots can also perform "follow-up" work, completing tasks designated or started by humans. In this paper, we summarize the development and testing of robots designed to improve future human exploration of space.

Economic Geology (Oil & Gas)

ERIC Educational Resources Information Center

Geotimes, 1972

1972-01-01

Briefly reviews the worldwide developments in petroleum geology in 1971, including exploration, new fields, and oil production. This report is condensed from the October Bulletin of the American Association of Petroleum Geologists. (PR)

Hormone replacement therapy in the developing countries.

PubMed

Oei, P L; Ratnam, S S

1998-05-01

The sales data of oestrogen replacement products for 8 developing countries from 1993 to 1995 were analyzed. The data from Malaysia, Pakistan, Taiwan, Thailand, Indonesia, Philippines and South Korea showed the increasing use of oestrogen replacement products. The total usage however varied widely, from only US$11,153 (Philippines in 1993) to as much as US$6,306,717 (Taiwan in 1995). In Singapore, where oestrogen replacement is an accepted and established form of therapy for the postmenopausal woman, there has been an increase in the usage of the nonoestrogen replacement products. There are multiple reasons for the increasing sales of hormone replacement products in the developing countries and these are explored in this article. In some of the developing countries, for example China and India, hormone replacement therapy has just been introduced. However, in those developing countries in which hormone replacement therapy is already available, sales figures show increasing usage. The future augurs well for hormone replacement therapy.

Space Resources Development: The Link Between Human Exploration and the Long-Term Commercialization of Space

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.

2000-01-01

In a letter to the NASA Administrator, Dan Goldin, in January of 1999, the Office of Management and Budget (OMB) stated the following . OMB recommends that NASA consider commercialization in a broader context than the more focused efforts to date on space station and space shuttle commercialization. We suggest that NASA examine architectures that take advantage of a potentially robust future commercial infrastructure that could dramatically lower the cost of future human exploration." In response to this letter, the NASA Human Exploration and Development of Space (HEDS) Enterprise launched the BEDS Technology & Commercialization Initiative (HTCI) to link technology and system development for human exploration with the commercial development of space to emphasize the "D" (Development) in BEDS. The development of technologies and capabilities to utilize space resources is the first of six primary focus areas in this program. It is clear that Space Resources Development (SRD) is key for both long-term human exploration of our solar system and to the long-term commercialization of space since: a) it provides the technologies, products, and raw materials to support efficient space transportation and in-space construction and manufacturing, and b) it provides the capabilities and infrastructure to allow outpost growth, self-sufficiency, and commercial space service and utility industry activities.

Operators selectively develop muddy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stremel, K.

1984-08-01

Restricted production has limited drilling in Amos Draw Field but activity continues on the fringes of this large producing field in the Powder River Basin. Drilling and exploration activity in the field are discussed.

50 CFR 29.32 - Mineral rights reserved and excepted.

Code of Federal Regulations, 2013 CFR

2013-10-01

... practicable, conduct all exploration, development, and production operations in such a manner as to prevent... to the minimum space compatible with the conduct of efficient mineral operations. Persons conducting...

50 CFR 29.32 - Mineral rights reserved and excepted.

Code of Federal Regulations, 2010 CFR

2010-10-01

... practicable, conduct all exploration, development, and production operations in such a manner as to prevent... to the minimum space compatible with the conduct of efficient mineral operations. Persons conducting...

50 CFR 29.32 - Mineral rights reserved and excepted.

Code of Federal Regulations, 2014 CFR

2014-10-01

... practicable, conduct all exploration, development, and production operations in such a manner as to prevent... to the minimum space compatible with the conduct of efficient mineral operations. Persons conducting...

50 CFR 29.32 - Mineral rights reserved and excepted.

Code of Federal Regulations, 2011 CFR

2011-10-01

... practicable, conduct all exploration, development, and production operations in such a manner as to prevent... to the minimum space compatible with the conduct of efficient mineral operations. Persons conducting...

50 CFR 29.32 - Mineral rights reserved and excepted.

Code of Federal Regulations, 2012 CFR

2012-10-01

... practicable, conduct all exploration, development, and production operations in such a manner as to prevent... to the minimum space compatible with the conduct of efficient mineral operations. Persons conducting...

Environmental Control and Life Support (ECLS) Integrated Roadmap Development

NASA Technical Reports Server (NTRS)

Metcalf, Jordan L.; Carrasquillo, Robyn; Bagdigian, Bob; Peterson, Laurie

2011-01-01

This white paper documents a roadmap for development of Environmental Control and Life Support (ECLS) Systems (ECLSS) capabilities required to enable beyond-Low Earth Orbit (LEO) Exploration missions. In many cases, the execution of this Exploration-based roadmap will directly benefit International Space Station (ISS) operational capability by resolving known issues and/or improving overall system reliability. In addition, many of the resulting products will be applicable across multiple Exploration elements such as Multi-Purpose Crew Vehicle (MPCV), Multi-Mission Space Exploration Vehicle (MMSEV), Deep Space Habitat (DSH), and Landers. Within the ECLS community, this white paper will be a unifying tool that will improve coordination of resources, common hardware, and technologies. It will help to align efforts to focus on the highest priority needs that will produce life support systems for future human exploration missions that will simply run in the background, requiring minimal crew interaction.

New technology innovations with potential for space applications

NASA Astrophysics Data System (ADS)

Krishen, Kumar

2008-07-01

Human exploration and development of space is being pursued by spacefaring nations to explore, use, and enable the development of space and expand the human experience there. The goals include: increasing human knowledge of nature's processes using the space environment; exploring and settling the solar system; achieving routine space travel; and enriching life on Earth through living and working in space. A crucial aspect of future space missions is the development of infrastructure to optimize safety, productivity, and costs. A major component of mission execution is operations management. NASA's International Space Station is providing extensive experience in both infrastructure and operations. In view of this, a vigorously organized approach is needed to implement successful space-, planet-, and ground-based research and operations that entails wise and efficient use of technical and human resources. Many revolutionary technologies being pursued by researchers and technologists may be vital in making space missions safe, reliable, cost-effective, and productive. These include: ionic polymer-metal composite technology; solid-state lasers; time-domain sensors and communication systems; high-temperature superconductivity; nanotechnology; variable specific impulse magneto plasma rocket; fuzzy logic; wavelet technology; and neural networks. An overview of some of these will be presented, along with their application to space missions.

Genetic improvement of plants for enhanced bio-ethanol production.

PubMed

Saha, Sanghamitra; Ramachandran, Srinivasan

2013-04-01

The present world energy situation urgently requires exploring and developing alternate, sustainable sources for fuel. Biofuels have proven to be an effective energy source but more needs to be produced to meet energy goals. Whereas first generation biofuels derived from mainly corn and sugarcane continue to be used and produced, the contentious debate between "feedstock versus foodstock" continues. The need for sources that can be grown under different environmental conditions has led to exploring newer sources. Lignocellulosic biomass is an attractive source for production of biofuel, but pretreatment costs to remove lignin are high and the process is time consuming. Genetically modified plants that have increased sugar or starch content, modified lignin content, or produce cellulose degrading enzymes are some options that are being explored and tested. This review focuses on current research on increasing production of biofuels by genetic engineering of plants to have desirable characteristics. Recent patents that have been filed in this area are also discussed.

Surface mining

Treesearch

Robert Leopold; Bruce Rowland; Reed Stalder

1979-01-01

The surface mining process consists of four phases: (1) exploration; (2) development; (3) production; and (4) reclamation. A variety of surface mining methods has been developed, including strip mining, auger, area strip, open pit, dredging, and hydraulic. Sound planning and design techniques are essential to implement alternatives to meet the myriad of laws,...

Toward a Critical Utopian and Pedagogical Methodology

ERIC Educational Resources Information Center

Firth, Rhiannon

2013-01-01

This article explores the possibility of developing an ethico-politically coherent and practical research framework for studying the learning and knowledge-production and dissemination processes of utopian groups and movements. It seeks to develop understanding of utopias by identifying and conceptualizing their pedagogical aspects. At the same…

DEVELOPING A PRODUCTION POSSIBILITY SET OF WILDLIFE SPECIES PERSISTENCE AND TIMBER HARVEST VALUE

EPA Science Inventory

An integrated model combing a wildlife population simulation model, and timber harvest and growth models was developed to explore the tradeoffs between the likelihood of persistence of a hypothetical wildlife species and timber harvest volumes on a landscape in the Central Oregon...

Broadcasting Education in the Age of New Media: Building Multimedia Products from the Academy

ERIC Educational Resources Information Center

Baltimore, Michael L.

2017-01-01

As our society continues to develop new technologies, the use of streaming technologies in higher education has lagged behind. The traditional academic landscape is dependent upon instructors to use commercial media products to deliver adjunct learning materials to the classroom. Faculty are also beginning to explore in the use of social media in…

Developing Biofuel in the Teaching Laboratory: Ethanol from Various Sources

ERIC Educational Resources Information Center

Epstein, Jessica L.; Vieira, Matthew; Aryal, Binod; Vera, Nicolas; Solis, Melissa

2010-01-01

In this series of experiments, we mimic a small-scale ethanol plant. Students discover that the practical aspects of ethanol production are determined by the quantity of biomass produced per unit land, rather than the volume of ethanol produced per unit of biomass. These experiments explore the production of ethanol from different sources: fruits,…

Non-feed application of rendered animal proteins for microbial production of eicosapentaenoic acid by the fungus Pythium irregulare

USDA-ARS?s Scientific Manuscript database

Rendered animal proteins are well suited for animal nutrition applications, but the market is maturing, and there is a need to develop new uses for these products. The objective of this study is to explore the possibility of using animal proteins as a nutrient source for industrial microorganism fe...

Energy efficiency and conservation in the developing world. World Bank policy paper. Energia: Eficiencia y conservacion en el mundo en desarrollo

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-01-01

Energy demand and production in developing countries are up, but efficiency of production and consumption are falling behind. The paper explores that issue and reviews the Bank's participation in energy projects. The paper conveys the Bank's strategy to promote efficiency through such means as transferring modern technology from the industrial countries and lending more selectively to energy-supply enterprises. The Bank identifies four factors that account for the differences in efficiency between the industrial and developing countries: energy pricing policies, control of energy supply enterprises, protection of energy-using industry from competition, and barriers to the productive functioning of markets.

Biofuels and North American agriculture--implications for the health and safety of North American producers.

PubMed

Gunderson, Paul D

2008-01-01

This decade has provided North American agricultural producers with opportunity to not only produce fiber and food, but also fuel and other industrial products. The drivers incenting this development could be sustained well into the future, therefore workforce safety and health implications are likely to persist for some time. Within production agriculture, the 'feedstock growth and harvest cycle' and 'transport' sectors possess the changing exposures experienced by workers. The Conference explored the following exposures: distiller's grains and bio-processing byproducts, spent catalyst, solvent brine, microbial agents, genetically modified organisms, discharge effluent, H2O dilutes, change in cropping patterns and resultant use of different seeding and harvest technologies, pests (whether target or non-target), and rural traffic resulting from concentrated movement of massive quantities of biomass and grain. Other issues of a more general public health nature such as watershed implications, other environmental impacts, emissions, uneven economic development potential, public safety issues associated with transport of both fuel and other industrial products, and rural emergency medical service need were explored. And, agronomic impacts were noted, including tillage change, potassium buildup in soil, nutrient depletion, sedimentation and erosion of tillable soil, and local esthetics. It was concluded that rural venues for formation and exploration of public policy need to be created.

Reflections on Engaging Students in the Process and Product of Strategy Development for Learning, Teaching, and Assessment: An Institutional Case Study

ERIC Educational Resources Information Center

Healey, Mick; Mason O'Connor, Kristine; Broadfoot, Patricia

2010-01-01

Two areas of growing importance for academic developers are: first, their involvement in the development of institutional and faculty learning and teaching strategies; and second, how to engage students in academic development activity at institutional, department and discipline levels. This paper explores both interests by considering how…

Workshop on Production and Uses of Simulated Lunar Materials

NASA Technical Reports Server (NTRS)

1991-01-01

A workshop entitled, Production and Uses of Simulated Lunar Materials, was convened to define the need for simulated lunar materials and examine related issues in support of extended space exploration and development. Lunar samples are a national treasure and cannot be sacrificed in sufficient quantity to test lunar resource utilization process adequately. Hence, the workshop focused on a detailed examination of the variety of potential simulants and the methods for their production.

Implementation plan for Bolivian Mineral Exploration Fund

USGS Publications Warehouse

Kirkemo, Harold

1978-01-01

Bolivia ranks second among world producers of tin and antimony, and first in bismuth production. Mineral exports in 1975 were valued at $314.2 million, nearly 60 percent of the value of all exports, and petroleum product exports totalled nearly $157 million, or 30 percent of the total. Tin accounted for 58 percent of the total value of metallic mineral exports. The central government derived about 19 percent of its total tax revenues in 1975 from the mining sector. The mining sector consists of the large, medium, and small mining subsectors, a classification established by the government. Individual operations are referred to as large, medium, or small depending upon the subsector into which they are classified. All large mining enterprises are owned and operated by a government corporation, COMIBOL; the medium and small operations are privately owned. COMIBOL's exports in 1975 were valued at $171.8 million or 70 percent of the total mineral exports; the medium mines accounted for $55.5 million or 23 percent, and the small mines for $17.5 million or 7 percent of the total. The combination of high operating costs, low productivity, inadequate ore reserves, and insufficient risk capital for exploration and development has led to the realization that there is an urgent need to improve the situation for mining in Bolivia. Proposals are being studied to revise the tax code, a program is underway to evaluate selected mineral deposits for possible exploration and development, and programs are under consideration to encourage minerals exploration. A minerals exploration plan is proposed which would offer technical and financial aid to various segments in the minerals field. A program, estimated to cost between $2 million and $2.5 million annually, and to be operated by a new agency in the Ministry of Mining and Metallurgy, is outlined.

Oil and gas developments in Far East in 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soeparjadi, R.A.; Valachi, L.Z.; Sosromihardjo, S.

1985-10-01

In 1984, the Far East region was no exception to the general worldwide slowdown in petroleum activities, although exploration and production were maintained at relatively high rates. Exploratory drilling decreased by 14%, and development drilling was down by 7%. The slowdown in Indonesia, the most active country for which data are available, was the main reason for the overall decline. In contrast, Brunei, Burma, Pakistan significantly increased their exploration drilling. Seismic activity in the region was up by 6%. A significant increase in marine seismic acquisition occurred in India, whereas Indonesia, Burma, and Brunei had a slowdown. As in themore » past, Indonesia maintained its role as the most active country in the region. No detailed exploration data were available for the People's Republic of China. The bulk of the exploration efforts in the region took place in relatively mature areas; frontier areas had a relatively low level of activity. There were no major oil or gas discoveries in the region, although Brunei, Burma, India, Indonesia, Malaysia, Pakistan, and Thailand had multiple successes in finding modest hydrocarbon reserves. Record acreage awards were made in Pakistan and Thailand, in contrast to Indonesia where awards were at the lowest level in recent years. A general increase of farm-out offering reflected the need to spread the risk of large exploration commitments. Production of both oil and gas increased significantly. Output of crude and condensate was up by 10% (an increase of 445,000 BOPD). A 21% increase was achieved in gas production, mainly due to expansions at Mobil's Arun and Huffcoi's Bontang LNG plants in North Sumatra and East Kalimantan, respectively. 31 figures, 9 tables.« less

Oil and gas developments in Far East in 1984

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soeparjadi, R.A.; Sosromihardjo, S.; Valachi, L.Z.

1985-10-01

In 1984, the Far East region was no exception to the general worldwide slowdown in petroleum activities, although exploration and production were maintained at relatively high rates. Exploratory drilling decreased by 14%, and development drilling was down by 7%. The slowdown in Indonesia, the most active country for which data are available, was the main reason for the overall decline. In contrast, Brunei, Burma, and Pakistan significantly increased their exploration drilling. Seismic activity in the region was up by 6%. A significant increase in marine seismic acquisition occurred in India, whereas Indonesia, Burma, and Brunei had a slowdown. As inmore » the past, Indonesia maintained its role as the most active country in the region. No detailed exploration data were available for the People's Republic of China. The bulk of the exploration efforts in the region took place in relatively mature areas; frontier areas had a relatively low level of activity. There were no major oil or gas discoveries in the region, although Brunei, Burma, India, Indonesia, Malaysia, Pakistan, and Thailand had multiple successes in finding modest hydrocarbon reserves. Record acreage awards were made in Pakistan and Thailand, in contrast to Indonesia where awards were at the lowest level in recent years. A general increase in farm-out offerings reflected the need to spread the risk of large exploration commitments. Production of both oil and gas increased significantly. Output of crude and condensate was up by 10% (an increase of 445,000 BOPD). A 21% increase was achieved in gas production, mainly due to expansions at Mobil's Arun and Huffco's Bontang LNG plants in North Sumatra and East Kalimantan, respectively.« less

Systems Engineering for Space Exploration Medical Capabilities

NASA Technical Reports Server (NTRS)

Mindock, Jennifer; Reilly, Jeffrey; Rubin, David; Urbina, Michelle; Hailey, Melinda; Hanson, Andrea; Burba, Tyler; McGuire, Kerry; Cerro, Jeffrey; Middour, Chris;

Bounding the Spacecraft Atmosphere Design Space for Future Exploration Missions

NASA Technical Reports Server (NTRS)

Lange, Kevin E.; Perka, Alan T.; Duffield, Bruce E.; Jeng, Frank F.

2005-01-01

The selection of spacecraft and space suit atmospheres for future human space exploration missions will play an important, if not critical, role in the ultimate safety, productivity, and cost of such missions. Internal atmosphere pressure and composition (particularly oxygen concentration) influence many aspects of spacecraft and space suit design, operation, and technology development. Optimal atmosphere solutions must be determined by iterative process involving research, design, development, testing, and systems analysis. A necessary first step in this process is the establishment of working bounds on the atmosphere design space.

SEASAT economic assessment. Volume 3: Offshore oil and natural gas industry case study and generalization

NASA Technical Reports Server (NTRS)

1975-01-01

The economic benefits of improved ocean condition, weather and ice forecasts by SEASAT satellites to the exploration, development and production of oil and natural gas in the offshore regions are considered. The results of case studies which investigate the effects of forecast accuracy on offshore operations in the North Sea, the Celtic Sea, and the Gulf of Mexico are reported. A methodology for generalizing the results to other geographic regions of offshore oil and natural gas exploration and development is described.

Developments in Radiation-Hardened Electronics Applicable to the Vision for Space Exploration

NASA Technical Reports Server (NTRS)

Keys, Andrew S.; Frazier, Donald O.; Patrick , Marshall C.; Watson, Michael D.; Johnson, Michael A.; Cressler, John D.; Kolawa, Elizabeth A.

2007-01-01

The Radiation Hardened Electronics for Space Exploration (RHESE) project develops the advanced technologies required to produce radiation hardened electronics, processors, and devices in support of the anticipated requirements of NASA's Constellation program. Methods of protecting and hardening electronics against the encountered space environment are discussed. Critical stages of a spaceflight mission that are vulnerable to radiation-induced interruptions or failures are identified. Solutions to mitigating the risk of radiation events are proposed through the infusion of RHESE technology products and deliverables into the Constellation program's spacecraft designs.

Economic issues with follow-on protein products.

PubMed

Lanthier, Michael; Behrman, Rachel; Nardinelli, Clark

2008-09-01

The economic effects of the possible introduction of 'follow-on' protein products have been the subject of recent debate. Here, we aim to explore the economic issues surrounding this debate using three measures: total sales, product complexity and patent expiry. Our analysis shows that the sales of therapeutic protein products are concentrated in a relatively small number of branded products, which may be the most attractive targets for follow-on development. For the years 2013-2015, we estimate that products representing US$20 billion in annual sales--approximately half of all sales in 2006--can be expected to lose patent protection.

Reel Science: An Ethnographic Study of Girls' Science Identity Development in and through Film

ERIC Educational Resources Information Center

Chaffee, Rachel L.

2016-01-01

This dissertation study contributes to the research on filmmaking and identity development by exploring the ways that film production provided unique opportunities for a team of four girls to engage in science, to develop identities in science, and to see and understand science differently. Using social practice, identity, and feminist theory and…

30 CFR 250.130 - Why does MMS conduct inspections?

Code of Federal Regulations, 2011 CFR

2011-07-01

... approved Exploration Plan or Development and Production Plans; or right-of-use and easement, and other... blowouts, fires, spillages, or other major accidents has been installed and is operating properly according...

30 CFR 250.286 - What is a DWOP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Deepwater Operations Plans (dwop) § 250.286 What is a DWOP? (a) A DWOP is a plan that provides sufficient information for MMS to review a deepwater... the regulations such as Exploration Plans, Development and Production Plans, and Development...

43 CFR 3900.40 - Multiple use development of leased or licensed lands.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL SHALE MANAGEMENT-GENERAL Oil Shale Management-Introduction § 3900.40 Multiple use development of leased or licensed... production of deposits of oil shale does not preclude the BLM from issuing other exploration licenses or...

43 CFR 3900.40 - Multiple use development of leased or licensed lands.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR RANGE MANAGEMENT (4000) OIL SHALE MANAGEMENT-GENERAL Oil Shale Management-Introduction § 3900.40 Multiple use development of leased or licensed... production of deposits of oil shale does not preclude the BLM from issuing other exploration licenses or...

43 CFR 3900.40 - Multiple use development of leased or licensed lands.

Code of Federal Regulations, 2014 CFR

2014-10-01

... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL SHALE MANAGEMENT-GENERAL Oil Shale Management-Introduction § 3900.40 Multiple use development of leased or licensed... production of deposits of oil shale does not preclude the BLM from issuing other exploration licenses or...

43 CFR 3900.40 - Multiple use development of leased or licensed lands.

Code of Federal Regulations, 2012 CFR

2012-10-01

... (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL SHALE MANAGEMENT-GENERAL Oil Shale Management-Introduction § 3900.40 Multiple use development of leased or licensed... production of deposits of oil shale does not preclude the BLM from issuing other exploration licenses or...

Community College Faculty Motivation for Basic Research, Teaching Research, and Professional Development

ERIC Educational Resources Information Center

Hardre, Patricia L.

2012-01-01

Community college faculty members often find themselves divided between what they want to do and what they can do. Knowing what motivates faculty to engage in professional development and scholarly productive activities provides critical information for administrators. The present study explored the motivational characteristics of community…

The Fun Bus: An Experiment in Nonformal Education through the Arts.

ERIC Educational Resources Information Center

Russell, Robert

A community development project employed the performing arts to focus community consciousness on local issues and problems in five towns in western Massachusetts. Performing artists and community development personnel organized town residents to hold workshops and, ultimately, theatrical productions to explore town issues. The team spent two weeks…

Current status and challenges for automotive battery production technologies

NASA Astrophysics Data System (ADS)

Kwade, Arno; Haselrieder, Wolfgang; Leithoff, Ruben; Modlinger, Armin; Dietrich, Franz; Droeder, Klaus

2018-04-01

Production technology for automotive lithium-ion battery (LIB) cells and packs has improved considerably in the past five years. However, the transfer of developments in materials, cell design and processes from lab scale to production scale remains a challenge due to the large number of consecutive process steps and the significant impact of material properties, electrode compositions and cell designs on processes. This requires an in-depth understanding of the individual production processes and their interactions, and pilot-scale investigations into process parameter selection and prototype cell production. Furthermore, emerging process concepts must be developed at lab and pilot scale that reduce production costs and improve cell performance. Here, we present an introductory summary of the state-of-the-art production technologies for automotive LIBs. We then discuss the key relationships between process, quality and performance, as well as explore the impact of materials and processes on scale and cost. Finally, future developments and innovations that aim to overcome the main challenges are presented.

Shale Gas Exploration and Development Progress in China and the Way Forward

NASA Astrophysics Data System (ADS)

Chen, Jianghua

2018-02-01

Shale gas exploration in China started late but is progressing very quickly with the strong support from Central Government. China has 21.8 tcm technically recoverable shale gas resources and 764.3 bcm proved shale gas reserve, mainly in marine facies in Sichuan basin. In 2016, overall shale gas production in China is around 7.9 bcm, while it is set to reach 10 bcm in 2017 and 30 bcm in 2020. BP is the only remaining IOC actor in shale gas exploration in China partnering with CNPC in 2 blocks in Sichuan basin. China is encouraging shale gas business both at Central level and at Provincial level through establishing development plan, continuation of subsidies and research funding. Engineering services for shale gas development and infrastructures are developing, while the overall cost and gas marketing conditions will be key factors for the success in shale gas industry.

Hydrogen production from algal biomass - Advances, challenges and prospects.

PubMed

Show, Kuan-Yeow; Yan, Yuegen; Ling, Ming; Ye, Guoxiang; Li, Ting; Lee, Duu-Jong

2018-06-01

Extensive effort is being made to explore renewable energy in replacing fossil fuels. Biohydrogen is a promising future fuel because of its clean and high energy content. A challenging issue in establishing hydrogen economy is sustainability. Biohydrogen has the potential for renewable biofuel, and could replace current hydrogen production through fossil fuel thermo-chemical processes. A promising source of biohydrogen is conversion from algal biomass, which is abundant, clean and renewable. Unlike other well-developed biofuels such as bioethanol and biodiesel, production of hydrogen from algal biomass is still in the early stage of development. There are a variety of technologies for algal hydrogen production, and some laboratory- and pilot-scale systems have demonstrated a good potential for full-scale implementation. This work presents an elucidation on development in biohydrogen encompassing biological pathways, bioreactor designs and operation and techno-economic evaluation. Challenges and prospects of biohydrogen production are also outlined. Copyright © 2018 Elsevier Ltd. All rights reserved.

Exploring barriers and opportunities in adopting crowdsourcing based new product development in manufacturing SMEs

NASA Astrophysics Data System (ADS)

Qin, Shengfeng; Van der Velde, David; Chatzakis, Emmanouil; McStea, Terry; Smith, Neil

2016-10-01

Crowdsourcing is an innovative business practice of obtaining needed services, ideas, or content or even funds by soliciting contributions from a large group of people (the `Crowd'). The potential benefits of utilizing crowdsourcing in product design are well-documented, but little research exists on what are the barriers and opportunities in adopting crowdsourcing in new product development (NPD) of manufacturing SMEs. In order to answer the above questions, a Proof of Market study is carried out on crowdsourcing-based product design under an Innovate UK funded Smart project, which aims at identifying the needs, challenges and future development opportunities associated with adopting crowdsourcing strategies for NPD. The research findings from this study are reported here and can be used to guide future development of crowdsourcing-based collaborative design methods and tools and provide some practical references for industry to adopt this new and emerging collaborative design method in their business.

Guatemala accelerates efforts to attract foreign E and D capital

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Guatemalan government, headed by recently elected President Alvaro Arzu, has embarked on an ambitious program of petroleum exploration and development with the goal of producing 40,000 b/d by 2000. Production averaged 16,000 b/d last fall and was to be raised to 25,000 b/d by year end 1996. Oil and gas exploration began in Guatemala in the 1920s, but production is currently limited to two regions in the Peten basin in northeastern Guatemala. Officials at the Ministry of Energy and Mines aim to encourage comprehensive evaluation of the Peten basin as well as exploration of the Amatique basin in southeasternmore » Guatemala and the Pacific basin on the country`s Pacific coast. The paper describes the Peten basin, the Amatique basin, the Pacific basin, bidding, and contract rules.« less

The Effect of Training on Italian Firms' Productivity: Microeconomic and Macroeconomic Perspectives

ERIC Educational Resources Information Center

Guerrazzi, Marco

2016-01-01

In this article, I explore the effect of training on the productivity of a sample of Italian firms and the impact of training on EU economic growth. Specifically, retrieving data from a survey performed by the Italian Institute for the Development of Vocational Training in 2009, I find that employer-sponsored training displays a positive and…

Using Stakeholder Marketing and Social Responsibility for New Product Development in Higher Education: A Business Spanish Model

ERIC Educational Resources Information Center

Huempfner, Lisa; Kopf, Dennis A.

2017-01-01

Higher education administrators are often faced with difficult choices in allocating limited resources for the creation of new programs. The purpose of this article is to explore the suitability of a new product, an integrated business Spanish major, by applying stakeholder marketing. In so doing, it provides a framework for the application of…

Widening ERTS applications

NASA Technical Reports Server (NTRS)

Mercanti, E. P.

1974-01-01

In less than two years of operation ERTS-1 is shown to have successfully completed its experimental mission and to be delivering an ever-increasing roster of benefits. The widening ERTS applications reviewed include air quality and weather modification, aid to oil exploration, ore-deposit exploration, short-lived event observation, flood area assessment and flood-plain mapping, land and water quality assessment, soil association mapping, crop production measurements, wildlife resources, drought and desertification studies, ground-water exploration, watershed surveys, snow and ice monitoring, surface water mapping, and iceberg surveys. Future projects and developments are also briefly reviewed.

30 CFR 250.130 - Why does BSEE conduct inspections?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Exploration Plan or Development and Production Plans; or right-of-use and easement, and other applicable laws..., fires, spillages, or other major accidents has been installed and is operating properly according to the...

30 CFR 250.130 - Why does BSEE conduct inspections?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Exploration Plan or Development and Production Plans; or right-of-use and easement, and other applicable laws..., fires, spillages, or other major accidents has been installed and is operating properly according to the...

30 CFR 250.130 - Why does BSEE conduct inspections?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Exploration Plan or Development and Production Plans; or right-of-use and easement, and other applicable laws..., fires, spillages, or other major accidents has been installed and is operating properly according to the...

Novel and Emerging Technologies for Produced Water Treatment, March 30, 2011

EPA Pesticide Factsheets

Development of unconventional gas resources, including coalbed methane (CBM), shale gas, and tight sand is currently one of the most rapidly growing trends in domestic oil and gas exploration and production.

Integrating landslide and liquefaction hazard and loss estimates with existing USGS real-time earthquake information products

USGS Publications Warehouse

Allstadt, Kate E.; Thompson, Eric M.; Hearne, Mike; Nowicki Jessee, M. Anna; Zhu, J.; Wald, David J.; Tanyas, Hakan

2017-01-01

The U.S. Geological Survey (USGS) has made significant progress toward the rapid estimation of shaking and shakingrelated losses through their Did You Feel It? (DYFI), ShakeMap, ShakeCast, and PAGER products. However, quantitative estimates of the extent and severity of secondary hazards (e.g., landsliding, liquefaction) are not currently included in scenarios and real-time post-earthquake products despite their significant contributions to hazard and losses for many events worldwide. We are currently running parallel global statistical models for landslides and liquefaction developed with our collaborators in testing mode, but much work remains in order to operationalize these systems. We are expanding our efforts in this area by not only improving the existing statistical models, but also by (1) exploring more sophisticated, physics-based models where feasible; (2) incorporating uncertainties; and (3) identifying and undertaking research and product development to provide useful landslide and liquefaction estimates and their uncertainties. Although our existing models use standard predictor variables that are accessible globally or regionally, including peak ground motions, topographic slope, and distance to water bodies, we continue to explore readily available proxies for rock and soil strength as well as other susceptibility terms. This work is based on the foundation of an expanding, openly available, case-history database we are compiling along with historical ShakeMaps for each event. The expected outcome of our efforts is a robust set of real-time secondary hazards products that meet the needs of a wide variety of earthquake information users. We describe the available datasets and models, developments currently underway, and anticipated products. 

Radiation Transmission Properties of In-Situ Materials

NASA Technical Reports Server (NTRS)

Heilbronn, L.; Townsend, L. W.; Cucinotta, F.; Kim, M. Y.; Miller, J.; Singleterry, R.; Thibeault, S.; Wilson, J.; Zeitlin, C. J.

2001-01-01

The development of a permanent human presence in space is a key element of NASA's strategic plan for the Human Exploration and Development of Space (HEDS). The habitation of the International Space Station (ISS) is one near-term HEDS objective; the exploration and settlement of the moon and Mars are long-term goals of that plan. Achieving these goals requires maintaining the health and safety of personnel involved in such space operations at a high level, while at the same time reducing the cost of those operations to a reasonable level. Among the limiting factors to prolonged human space operations are the health risks from exposure to the space ionizing radiation environment. In order to keep the risk of radiation induced cancer at acceptable levels, it is necessary to provide adequate shielding from the ionizing radiation environment. The research presented here is theoretical and ground-based experimental study of the neutron production from interactions of GCR-like particles in various shielding components. An emphasis is placed here on research that will aid in the development of in-situ resource utilization. The primary goal of the program is to develop an accurate neutron-production model that is relevant to the NASA HEDS program of designing technologies that will be used in the development of effective shielding countermeasures. A secondary goal of the program is the development of an experimental data base of neutron production cross sections and thick-target yields which will aid model development.

Engineering development of selective agglomeration: Task 5, Bench- scale process testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-09-01

Under the overall objectives of DOE Contract ``Engineering Development of Selective Agglomeration,`` there were a number of specific objectives in the Task 5 program. The prime objectives of Task 5 are highlighted below: (1) Maximize process performance in pyritic sulfur rejection and BTU recovery, (2) Produce a low ash product, (3) Compare the performance of the heavy agglomerant process based on diesel and the light agglomerant process using heptane, (4) Define optimum processing conditions for engineering design, (5) Provide first-level evaluation of product handleability, and (6) Explore and investigate process options/ideas which may enhance process performance and/or product handleability.

Engineering development of selective agglomeration: Task 5, Bench- scale process testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-09-01

Under the overall objectives of DOE Contract Engineering Development of Selective Agglomeration,'' there were a number of specific objectives in the Task 5 program. The prime objectives of Task 5 are highlighted below: (1) Maximize process performance in pyritic sulfur rejection and BTU recovery, (2) Produce a low ash product, (3) Compare the performance of the heavy agglomerant process based on diesel and the light agglomerant process using heptane, (4) Define optimum processing conditions for engineering design, (5) Provide first-level evaluation of product handleability, and (6) Explore and investigate process options/ideas which may enhance process performance and/or product handleability.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoak, T.E.; Klawitter, A.L.

Fractured production trends in Piceance Basin Cretaceous-age Mesaverde Group gas reservoirs are controlled by subsurface structures. Because many of the subsurface structures are controlled by basement fault trends, a new interpretation of basement structure was performed using an integrated interpretation of Landsat Thematic Mapper (TM), side-looking airborne radar (SLAR), high altitude, false color aerial photography, gas and water production data, high-resolution aeromagnetic data, subsurface geologic information, and surficial fracture maps. This new interpretation demonstrates the importance of basement structures on the nucleation and development of overlying structures and associated natural fractures in the hydrocarbon-bearing section. Grand Valley, Parachute, Rulison, Plateau,more » Shire Gulch, White River Dome, Divide Creek and Wolf Creek fields all produce gas from fractured tight gas sand and coal reservoirs within the Mesaverde Group. Tectonic fracturing involving basement structures is responsible for development of permeability allowing economic production from the reservoirs. In this context, the significance of detecting natural fractures using the intergrated fracture detection technique is critical to developing tight gas resources. Integration of data from widely-available, relatively inexpensive sources such as high-resolution aeromagnetics, remote sensing imagery analysis and regional geologic syntheses provide diagnostic data sets to incorporate into an overall methodology for targeting fractured reservoirs. The ultimate application of this methodology is the development and calibration of a potent exploration tool to predict subsurface fractured reservoirs, and target areas for exploration drilling, and infill and step-out development programs.« less

Analysis of improved government geological map information for mineral exploration: Incorporating efficiency, productivity, effectiveness, and risk considerations

USGS Publications Warehouse

Bernknopf, R.L.; Wein, A.M.; St-Onge, M. R.; Lucas, S.B.

2007-01-01

This bulletin/professional paper focuses on the value of geoscientific information and knowledge, as provided in published government bedrock geological maps, to the mineral exploration sector. An economic model is developed that uses an attribute- ranking approach to convert geological maps into domains of mineral favourability. Information about known deposits in these (or analogous) favourability domains allow the calculation of exploration search statistics that provide input into measures of exploration efficiency, productivity, effectiveness, risk, and cost stemming from the use of the published geological maps. Two case studies, the Flin Flon Belt (Manitoba and Saskatchewan) and the south Baffin Island area (Nunavut), demonstrate that updated, finer resolution maps can be used to identify more exploration campaign options, and campaigns thats are more efficient, more effective, and less risky than old, coarser resolution maps when used as a guide for mineral exploration. The Flin Flon Belt study illustrates that an updated, coarser resolution bedrock map enables improved mineral exploration efficiency, productivity, and effectiveness by locating 60% more targets and supporting an exploration campaign that is 44% more efficient. Refining the map resolution provides an additional 17% reduction in search effort across all favourable domains and a 55% reduction in search effort in the most favourable domain. The south Baffin Island case study projects a 40% increase in expected targets and a 27% reduction in search effort when the updated, finer resolution map is used in lieu of the old, coarser resolution map. On southern Baffin Island, the economic value of the up dated map ranges from CAN$2.28 million to CAN$15.21 million, which can be compared to the CAN$1.86 million that it cost to produce the map (a multiplier effect of up to eight).

Exploring the Usefulness of MISR-HR Products to Estimate Maize Crop Extent and Using Field Evidence to Evaluate the Results in South Africa's Free State Province

NASA Astrophysics Data System (ADS)

Verstraete, M. M.; Knox, N. M.; Hunt, L. A.; Kleyn, L.

2014-12-01

The MISR instrument on NASA's Terra platform has been operating for almost 15 years. Standard products are generated at a spatial resolution of 1.1 km or coarser, but a recently developed method to re-analyze the Level-1B2 data allows the retrieval of biogeophysical products at the native spatial resolution of the instrument (275 m). This development opens new opportunities to better address issues such as the management of agricultural production and food security. South African maize production is of great economic and social importance, not only nationally, but on the global market too, being one of the top ten maize producing countries. Seasonal maize production statistics are currently based on a combination of field measurements and estimates derived from manually digitizing high resolution imagery from the SPOT satellite. The field measurements are collected using the Producer Independent Crop Estimate System (PICES) developed by Crop Estimates Committee of the Department of Agriculture, Forestry and Fisheries. There is a strong desire to improve the quality of these statistics, to generate those earlier, and to automate the process to encompass larger areas. This paper will explore the feasibility of using the MISR-HR spectral and directional products, combined with the finer spatial resolution and the relatively frequent coverage afforded by that instrument, to address these needs. The study area is based in the Free State, South Africa, one of the primary maize growing areas in the country, and took place during the 2012-2013 summer growing season. The significance of the outcomes will be evaluated in the context of the 14+ years of available MISR data.

Developing Online Tutorials to Improve Information Literacy Skills for Second-Year Nursing Students of University College Dublin

ERIC Educational Resources Information Center

Walters, Kirsteen; Bolich, Cecilia; Duffy, Daniel; Quinn, Ciarán; Walsh, Kathryn; Connolly, Sarah

2015-01-01

This article explores the process of developing online tutorials for a specified student group, in this case Second-Year Nursing students in University College Dublin. The product was commissioned by the Health Sciences Library and the UCD School of Nursing, Midwifery, and Health Systems. It was developed as a "Capstone Project" for part…

Trends in liability affecting technical writers

NASA Technical Reports Server (NTRS)

Driskill, L. P.

1981-01-01

Liability of technical writers for defective products is explored. Documents generated during a product's life cycle (including design memos, design tests, clinical trials, trial use reports, letters, and proposals) become relevant because they are likely to become the only available means of showing that the product was not defectively designed. These documents become the evidence that the product underwent balanced and well considered planning, development, testing, quality control, and field testing. The predicted increased involvement of technical writers in the prevention and defense of product liability claims is cited in view of a greater number of cases turning on "failure to warn".

Processing Challenges and Opportunities of Camel Dairy Products

PubMed Central

Seifu, Eyassu; Ipsen, Richard; Kurtu, Mohamed Y.; Hansen, Egon Bech

2017-01-01

A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent scientific studies confirm that it is a rich source of bioactive, antimicrobial, and antioxidant substances. The current literature concerning product design and functional potential of camel milk is fragmented in terms of time, place, and depth of the research. Therefore, it is essential to understand the fundamental features of camel milk and initiate detailed multidisciplinary research to fully explore and utilize its functional and technological properties. PMID:29109953

Managing design for manufacture and assembly in the development of MEMS-based products

NASA Astrophysics Data System (ADS)

Hsu, Hung-Yao; Narasimhan, Nachchinarkkinian; Hariz, Alex J.

2006-12-01

Design for manufacturability, assembly and reliability of MEMS products is being applied to a multitude of novel MEMS products to make up for the lack of "Standard Process for MEMS" concept. The latter has proved a major handicap in commercialization of MEMS devices when compared to integrated circuits products. Furthermore, an examination of recent engineering literature seems to suggest convergence towards the development of the design for manufacturability and reliability of MEMS products. This paper will highlight the advantages and disadvantages of conventional techniques that have been pursued up to this point to achieve commercialization of MEMS products, identify some of the problems slowing down development, and explore measures that could be taken to try to address those problems. Successful commercialization critically depends on packaging and assembly, manufacturability, and reliability for micro scale products. However, a methodology that appropriately shadows next generation knowledge management will undoubtedly address most of the critical problems that are hampering development of MEMS industries. Finally this paper will also identify contemporary issues that are challenging the industry in regards to product commercialization and will recommend appropriate measures based on knowledge flow to address those shortcomings and lay out plans to expedient and successful paths to market.

The voice of the customer--Part 2: Benchmarking battery chargers against the Consumer's Ideal Product.

PubMed

Bauer, S M; Lane, J P; Stone, V I; Unnikrishnan, N

1998-01-01

The Rehabilitation Engineering Research Center on Technology Evaluation and Transfer is exploring how the end users of assistive technology devices define the ideal device. This work is called the Consumer Ideal Product program. In this work, end users identify and establish the importance of a broad range of product design features, along with the related product support and service provided by manufacturers and vendors. This paper describes a method for systematically transforming end-user defined requirements into a form that is useful and accessible to product designers, manufacturers, and vendors. In particular, product requirements, importance weightings, and metrics are developed from the Consumer Ideal Product battery charger outcomes. Six battery charges are benchmarked against these product requirements using the metrics developed. The results suggest improvements for each product's design, service, and support. Overall, the six chargers meet roughly 45-75% of the ideal product's requirements. Many of the suggested improvements are low-cost changes that, if adopted, could provide companies a competitive advantage in the marketplace.

Getting Planetary Data into the Hands of Educators: Recommendations from a Community Discussion

NASA Astrophysics Data System (ADS)

Shipp, S.; Lowes, L.; Hammon, A.; Higbie, M.; Klug, S.; Lindstrom, M.; Stockman, S.; Wise, J.

2004-12-01

In March 2004 a community of approximately 60 researchers, formal and informal education specialists, classroom educators, data archivists, and educational product developers came together for a day-long conference to discuss the challenges in bringing planetary data into the classroom. The conference was hosted by the Solar System Exploration Education Forum and the South Central Organization of Researchers and Educators of NASA's Office of Space Science Support Network. The workshop was intended to: initiate a dialog among those interested in identifying paths for bringing planetary data to educators; better understand key challenges facing educators who are working with planetary data and issues with gaining access to data; identify common aspects of success of programs and products developed to make data accessible in educational venues; and finally, identify the remaining challenges and make recommendations for how the community should move forward to bring these data into the classroom. Presentations by researchers and educational specialists encompassed the facilitation of accessing data, effective use of data in the classroom, availability of data for use by the educational community, and paths for accessing and using mission data. Panel discussions explored the experiences of researchers, educators, and product developers in creating and implementing programs and products and the challenges remaining for integrating planetary data into educational environments. Discussion among participants resulted in a series of recommendations for the development and implementation of successful programs, including: 1) the intended audience should play an active role in the design and development process; 2) program and product implementation should incorporate adequate training and support for intended users; 3) data access needs to be made easier, perhaps requiring the filtering of raw data and new user interfaces; 4) product developers should present data within the context of a lesson or an exploration that is appropriate for the age level, with ties to standards, assessments, and connections to other disciplines such as language arts and math to ease the time burden on the classroom educator; 5) data need to be accessible within a broad context of important scientific questions and understanding; and 6) the potential community involved in the educational use of planetary data is large -- resources such as master-teachers, museums, pre-service faculty, minority organizations, amateur astronomers and others should be involved and leveraged. The complete list of recommendations, presentations, and participants can be found at (http://www.lpi.usra.edu/score). This conference was intended to initiate community dialog on the use of planetary data in the classroom. Future conferences and workshops are planned to continue the discussion of issues and challenges.

Developing End-User Innovation from Circuits of Learning

ERIC Educational Resources Information Center

Fosstenløkken, Siw M.

2015-01-01

Purpose: This paper aims to raise the question of how end-user product innovation is developed by exploring the underlying learning mechanisms that drive such idea realization in practice. A trialogical learning perspective from educational science is applied as an analytical approach to enlighten the black box of learning dynamics in user…

Content Analysis of Language-Promoting Teaching Strategies Used in Infant-Directed Media

ERIC Educational Resources Information Center

Vaala, Sarah E.; Linebarger, Deborah L.; Fenstermacher, Susan K.; Tedone, Ashley; Brey, Elizabeth; Barr, Rachel; Moses, Annie; Shwery, Clay E.; Calvert, Sandra L.

2010-01-01

The number of videos produced specifically for infants and toddlers has grown exponentially in the last decade. Many of these products make educational claims regarding young children's language development. This study explores infant media producer claims regarding language development, and the extent to which these claims reflect different…

Consideration of historical authenticity in heritage tourism planning and development

Treesearch

Craig Wiles; Gail Vander Stoep

2008-01-01

A review of heritage tourism literature reveals a fundamental tension over the use, function, and degree of authenticity of historic resources used for tourism development. Using a case study approach, this paper explores how stakeholder beliefs regarding historical authenticity influence the heritage tourism products, services, and experiences created for visitors and...

Planning and Second Language Development in Task-Based Synchronous Computer-Mediated Communication

ERIC Educational Resources Information Center

Hsu, Hsiu-Chen

2012-01-01

This dissertation explored the effect of two planning conditions (the multiple planning condition with rehearsal and online planning time, and the single planning condition with online planning time only) on L2 production complexity and accuracy and the subsequent development of these two linguistic areas in the context of written synchronous…

Final review of analog field campaigns for In Situ Resource Utilization technology and capability maturation

NASA Astrophysics Data System (ADS)

Sanders, Gerald B.; Larson, William E.

2015-05-01

A key aspect of enabling an affordable and sustainable program of human exploration beyond low Earth orbit is the ability to locate, extract, and harness the resources found in space to reduce what needs to be launched from Earth's deep gravity well and to minimize the risk of dependence on Earth for survival. Known as In Situ Resource Utilization or ISRU, the ability to convert space resources into useful and mission critical products has been shown in numerous studies to be mission and architecture enhancing or enabling. However at the time of the release of the US Vision for Space Exploration in 2004, only concept feasibility hardware for ISRU technologies and capabilities had been built and tested in the laboratory; no ISRU hardware had ever flown in a mission to the Moon or Mars. As a result, an ISRU development project was established with phased development of multiple generations of hardware and systems. To bridge the gap between past ISRU feasibility hardware and future hardware needed for space missions, and to increase confidence in mission and architecture planners that ISRU capabilities would meet exploration needs, the ISRU development project incorporated extensive ground and analog site testing to mature hardware, operations, and interconnectivity with other exploration systems linked to ISRU products. This report documents the series of analog test activities performed from 2008 to 2012, the stepwise progress achieved, and the end-to-end system and mission demonstrations accomplished in this test program.

Development of an Exploration-Class Cascade Distillation System: Flight Like Prototype Preliminary Design

NASA Technical Reports Server (NTRS)

Callahan, Michael R.; Sargusingh, Miriam J.

2015-01-01

The ability to recover and purify water through physiochemical processes is crucial for realizing long-term human space missions, including both planetary habitation and space travel. Because of their robust nature, distillation systems have been actively pursued as one of the technologies for water recovery. One such technology is the Cascade Distillation System (CDS) a multi-stage vacuum rotary distiller system designed to recover water in a microgravity environment. Its rotating cascading distiller operates similarly to the state of the art (SOA) vapor compressor distiller (VCD), but its control scheme and ancillary components are judged to be straightforward and simpler to implement into a successful design. Through the Advanced Exploration Systems (AES) Life Support Systems (LSS) Project, the NASA Johnson Space Center (JSC) in collaboration with Honeywell International is developing a second generation flight forward prototype (CDS 2.0). The key objectives for the CDS 2.0 design task is to provide a flight forward ground prototype that demonstrates improvements over the SOA system in the areas of increased reliability and robustness, and reduced mass, power and volume. It will also incorporate exploration-class automation. The products of this task are a preliminary flight system design and a high fidelity prototype of an exploration class CDS. These products will inform the design and development of the third generation CDS which is targeted for on-orbit DTO. This paper details the preliminary design of the CDS 2.0.

43 CFR 3280.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources... resulting in: (1) Diligent development; (2) Efficient exploration, production and utilization of the resource; (3) Conservation of natural resources; and (4) Prevention of waste. Reasonably proven to produce...

43 CFR 3280.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources... resulting in: (1) Diligent development; (2) Efficient exploration, production and utilization of the resource; (3) Conservation of natural resources; and (4) Prevention of waste. Reasonably proven to produce...

43 CFR 3280.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources... resulting in: (1) Diligent development; (2) Efficient exploration, production and utilization of the resource; (3) Conservation of natural resources; and (4) Prevention of waste. Reasonably proven to produce...

43 CFR 3280.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF THE INTERIOR MINERALS MANAGEMENT (3000) GEOTHERMAL RESOURCES UNIT AGREEMENTS Geothermal Resources... resulting in: (1) Diligent development; (2) Efficient exploration, production and utilization of the resource; (3) Conservation of natural resources; and (4) Prevention of waste. Reasonably proven to produce...

Consumer demand as a driver of improved working conditions: the 'Ergo-Brand' proposition.

PubMed

Neumann, W Patrick; Dixon, Shane M; Nordvall, Anna-Carin

2014-01-01

This article develops and explores the 'Ergo-Brand' proposition, which posits that consumers may prefer to buy goods that are made under good working conditions (GWCs). This preference would enhance a differentiation strategy for companies, thereby fostering the application of ergonomics in production. This proposition is developed in the context of a narrative review of the literature on 'ethical consumerism'. This is supplemented with a survey study, conducted in both Canada and Sweden (n = 141) to explore this proposition. Results indicate that consumers would prefer goods made under GWCs, but not unconditionally as quality and price concerns were ranked higher. Access to information on the working conditions in production was seen as a barrier. Nevertheless, the Ergo-Brand concept may be a viable avenue in promoting attention towards ergonomics in companies - particularly if consumer habits are subject to intervention by advertising. Further research on this strategy is warranted.

Streptomyces Exploration: Competition, Volatile Communication and New Bacterial Behaviours.

PubMed

Jones, Stephanie E; Elliot, Marie A

2017-07-01

Streptomyces bacteria are prolific producers of specialized metabolites, and have a well studied, complex life cycle. Recent work has revealed a new type of Streptomyces growth termed 'exploration' - so named for the ability of explorer cells to rapidly traverse solid surfaces. Streptomyces exploration is stimulated by fungal interactions, and is associated with the production of an alkaline volatile organic compound (VOC) capable of inducing exploration by other streptomycetes. Here, we examine Streptomyces exploration from the perspectives of interkingdom interactions, pH-induced morphological switches, and VOC-mediated communication. The phenotypic diversity that can be revealed through microbial interactions and VOC exposure is providing us with insight into novel modes of microbial development, and an opportunity to exploit VOCs to stimulate desired microbial behaviours. Copyright © 2017 Elsevier Ltd. All rights reserved.

Chemistry and Biology of the Caged Garcinia Xanthones

PubMed Central

Chantarasriwong, Oraphin; Batova, Ayse; Chavasiri, Warinthorn

2011-01-01

Natural products have been a great source of many small molecule drugs for various diseases. In spite of recent advances in biochemical engineering and fermentation technologies that allow us to explore microorganisms and the marine environment as alternative sources of drugs, more than 70% of the current small molecule therapeutics derive their structures from plants used in traditional medicine. Natural-product-based drug discovery relies heavily on advances made in the sciences of biology and chemistry. Whereas biology aims to investigate the mode of action of a natural product, chemistry aims to overcome challenges related to its supply, bioactivity, and target selectivity. This review summarizes the explorations of the caged Garcinia xanthones, a family of plant metabolites that possess a unique chemical structure, potent bioactivities, and a promising pharmacology for drug design and development. PMID:20648491

Systems Engineering for Space Exploration Medical Capabilities

NASA Technical Reports Server (NTRS)

Mindock, Jennifer; Reilly, Jeffrey; Urbina, Michelle; Hailey, Melinda; Rubin, David; Reyes, David; Hanson, Andrea; Burba, Tyler; McGuire, Kerry; Cerro, Jeffrey;

Rocket Science: The Shuttle's Main Engines, though Old, Are not Forgotten in the New Exploration Initiative

NASA Technical Reports Server (NTRS)

Covault, Craig

2005-01-01

The Space Shuttle Main Engine (SSME), developed 30 years ago, remains a strong candidate for use in the new Exploration Initiative as part of a shuttle-derived heavy-lift expendable booster. This is because the Boeing-Rocket- dyne man-rated SSME remains the most highly efficient liquid rocket engine ever developed. There are only enough parts for 12-15 existing SSMEs, however, so one NASA option is to reinitiate SSME production to use it as a throw-away, as opposed to a reusable, powerplant for NASA s new heavy-lift booster.

Non-timber forest products: local livelihoods and integrated forest management

Treesearch

Iain Davidson-Hunt; Luc C. Duchesne; John C. Zasada

2001-01-01

In October of 1999 a conference was held in Kenora, Ontario, Canada, to explore the non-timber forest products (NTFPs) of boreal and cold temperate forests. Up to this time, the concept of NTFP, was one that had been developed largely for tropical and subtropical forests. An extensive body of literature exists on a wide range of topics for the NTFPs of tropical and...

Budgetary and Programmatic Fluctuations during the System Development and Demonstration Phase: A Case Study of the Marine Corps H-1 Upgrade Program

DTIC Science & Technology

2007-12-01

impact of economic change might include a closing factory, market manipulation, the signing of international trade 17 treaties, or the global...Refinement System Intergration System Demonstration Concept Decision BA C LRIP Full-Rate Production & Deployment System Development and Demonstration...BLOCK III Concept Exploration Component Advanced Development Concept and Technology Development System Intergration System Demonstration Decision Review

Flexible and Low-Cost Measurements for Space Software Development- The Measurements Exploration Framework

NASA Astrophysics Data System (ADS)

Marculescu, Bogdan; Feldt, Robert; Torkar, Richard; Green, Lars-Goran; Liljegren, Thomas; Hult, Erika

2011-08-01

Verification and validation is an important part of software development and accounts for significant amounts of the costs associated with such a project. For developers of life or mission critical systems, such as software being developed for space applications, a balance must be reached between ensuring the quality of the system by extensive and rigorous testing and reducing costs and allowing the company to compete.Ensuring the quality of any system starts with a quality development process. To evaluate both the software development process and the product itself, measurements are needed. A balance must be then struck between ensuring the best possible quality of both process and product on the one hand, and reducing the cost of performing requirements on the other.A number of measurements have already been defined and are being used. For some of these, data collection can be automated as well, further lowering costs associated with implementing them. In practice, however, there may be situations where existing measurements are unsuitable for a variety of reasons.This paper describes a framework for creating low cost, flexible measurements in areas where initial information is scarce. The framework, called The Measurements Exploration Framework, is aimed in particular at the Space Software development industry and was developed is such an environment.

Computer aided design and manufacturing: analysis and development of research issues

NASA Astrophysics Data System (ADS)

Taylor, K.; Jadeja, J. C.

2005-11-01

The paper focuses on the current issues in the areas of computer aided manufacturing and design. The importance of integrating CAD and CAM is analyzed. The associated issues with the integration and recent advancements in this field have been documented. The development of methods for enhancing productivity is explored. A research experiment was conducted in the laboratories of West Virginia University with an objective to portray effects of various machining parameters on production. Graphical results and their interpretations are supplied to better realize the main purpose of the experimentation.

Development of Improved and Novel Thermal Control Coatings (Preprint)

DTIC Science & Technology

2007-05-01

a ZnO-based coating (Figure 5). A product offered by the 3M Corporation composed of hollow soda - lime borosilicate spheres with diameters ranging...as well as the current zinc oxide based coatings. In addition, a novel pigment concept based on hollow silica particles is continuing to be explored...coatings. In addition, a novel pigment concept based on hollow silica particles is continuing to be explored as an extremely space durable and

Assessment of New Approaches in Geothermal Exploration Decision Making: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akar, S.; Young, K. R.

Geothermal exploration projects have significant amount of risk associated with uncertainties encountered in the discovery of the geothermal resource. Understanding when and how to proceed in an exploration program, and when to walk away from a site, are two of the largest challenges for increased geothermal deployment. Current methodologies for exploration decision making is left to subjective by subjective expert opinion which can be incorrectly biased by expertise (e.g. geochemistry, geophysics), geographic location of focus, and the assumed conceptual model. The aim of this project is to develop a methodology for more objective geothermal exploration decision making at a givenmore » location, including go-no-go decision points to help developers and investors decide when to give up on a location. In this scope, two different approaches are investigated: 1) value of information analysis (VOIA) which is used for evaluating and quantifying the value of a data before they are purchased, and 2) enthalpy-based exploration targeting based on reservoir size, temperature gradient estimates, and internal rate of return (IRR). The first approach, VOIA, aims to identify the value of a particular data when making decisions with an uncertain outcome. This approach targets the pre-drilling phase of exploration. These estimated VOIs are highly affected by the size of the project and still have a high degree of subjectivity in assignment of probabilities. The second approach, exploration targeting, is focused on decision making during the drilling phase. It starts with a basic geothermal project definition that includes target and minimum required production capacity and initial budgeting for exploration phases. Then, it uses average temperature gradient, reservoir temperature estimates, and production capacity to define targets and go/no-go limits. The decision analysis in this approach is based on achieving a minimum IRR at each phase of the project. This second approach was determined to be less subjective, since it requires less subjectivity in the input values.« less

Vacuum cooling of meat products: current state-of-the-art research advances.

PubMed

Feng, Chaohui; Drummond, Liana; Zhang, Zhihang; Sun, Da-Wen; Wang, Qijun

2012-01-01

Vacuum cooling (VC) is commonly applied for cooling of several foodstuffs, to provide exceptionally rapid cooling rates with low energy consumption and resulting in high-quality food products. However, for products such as meat and cooked meat products, the higher cooling loss of vacuum cooling compared with established methods still means lower yields, and important meat quality parameters can be negatively affected. Substantial efforts during the past ten years have aimed to improve the technology in order to offer the meat industry, especially the cooked meat industry, optimized production in terms of safety regulations and guidelines, as well as meat quality. This review presents and discusses recent VC developments directed to the cooked meat industry. The principles of VC, and the basis for improvements of this technology, are firstly discussed; future prospects for research and development in this area are later explored, particularly in relation to cooling of cooked meat and meat products.

Visayan Basin - the birthplace of Philippine petroleum exploration revisited

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rillera, F.G.; Durkee, E.F.

1994-07-01

Petroleum exploration in the Philippines has its roots in the Visayan Basin in the central Philippines. This is a Tertiary basin with up to 30,000 ft of sedimentary fill. With numerous surface oil and gas manifestations known as early as 1888, the area was the site of the first attempts to establish commercial petroleum production in the country. Over the past 100 years, more than 200 wells have been drilled in the basin. Several of these have yielded significant oil and gas shows. Production, albeit noncommercial in scale, has been demonstrated to be present in some places. A review ofmore » past exploration data reveals that many of the earlier efforts failed due to poorly located tests from both structural and stratigraphic standpoints. Poor drilling and completion technology and lack of funding compounded the problems of early explorationists. Because of this, the basin remains relatively underexplored. A recent assessment by COPLEX and E.F. Durkee and Associates demonstrates the presence of many untested prospects in the basin. These prospects may contain recoverable oil and gas potential on the order of 5 to 10 MMBO onshore and 25 to 100 MMBO offshore. With new exploration ideas, innovative development concepts, and the benefit of modern technology, commercial oil and gas production from the basin may yet be realized.« less

Explore GPM IMERG and Other Global Precipitation Products with GES DISC GIOVANNI

NASA Technical Reports Server (NTRS)

Liu, Zhong; Ostrenga, Dana M.; Vollmer, Bruce; MacRitchie, Kyle; Kempler, Steven

2015-01-01

New features and capabilities in the newly released GIOVANNI allow exploring GPM IMERG (Integrated Multi-satelliE Retrievals for GPM) Early, Late and Final Run global half-hourly and monthly precipitation products as well as other precipitation products distributed by the GES DISC such as TRMM Multi-Satellite Precipitation Analysis (TMPA), MERRA (Modern Era Retrospective-Analysis for Research and Applications), NLDAS (North American Land Data Assimilation Systems), GLDAS (Global Land Data Assimilation Systems), etc. GIOVANNI is a web-based tool developed by the GES DISC (Goddard Earth Sciences and Data Information Services Center) to visualize and analyze Earth science data without having to download data and software. The new interface in GIOVANNI allows searching and filtering precipitation products from different NASA missions and projects and expands the capabilities to inter-compare different precipitation products in one interface. Knowing differences in precipitation products is important to identify issues in retrieval algorithms, biases, uncertainties, etc. Due to different formats, data structures, units and so on, it is not easy to inter-compare precipitation products. Newly added features and capabilities (unit conversion, regridding, etc.) in GIOVANNI make inter-comparisons possible. In this presentation, we will describe these new features and capabilities along with examples.

Continued development of mature field: west Cameron Block 45 field, Gulf of Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brand, S.R.; Fox, J.F.

Initial acreage acquisition and exploration of the West Cameron Block 45 field, located offshore Louisiana, were based on reconnaissance gravity surveys that revealed an anomalous high across the area. Several phases of development drilling activity have been conducted in the field since its discovery in March 1949. Nearly four decades after initial exploration began, an integrated field study incorporating all available geological, geophysical, petrophysical, and engineering data was undertaken to evaluate the remaining potential of the field. As a result of this study, a detailed structural and stratigraphic framework was developed, the controls on reservoir production performance were established, andmore » additional drillable prospects were delineated.« less

43 CFR 3590.0-1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SOLID MINERALS (OTHER THAN COAL) EXPLORATION AND MINING..., testing, development, mining and processing operations and production practices without waste or avoidable...

43 CFR 3590.0-1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SOLID MINERALS (OTHER THAN COAL) EXPLORATION AND MINING..., testing, development, mining and processing operations and production practices without waste or avoidable...

43 CFR 3590.0-1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SOLID MINERALS (OTHER THAN COAL) EXPLORATION AND MINING..., testing, development, mining and processing operations and production practices without waste or avoidable...

43 CFR 3590.0-1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) SOLID MINERALS (OTHER THAN COAL) EXPLORATION AND MINING..., testing, development, mining and processing operations and production practices without waste or avoidable...

Coordinated Development and Deployment of Scenarios for Sustained Assessment

NASA Astrophysics Data System (ADS)

Lipschultz, F.; Weaver, C. P.; Leidner, A. K.; Delgado, A.; Grambsch, A.

2017-12-01

There has been a clear need for a more coordinated Federal government approach for authoritative, climate-relevant scenarios to support growing demands by decision-makers, to meet stakeholder needs for consistent approaches and guidance, and to better address the needs of the impacts, adaptation and vulnerability community. To begin to satisfy these decision-support needs, in early 2015 the U.S. Global Change Research Program (USGCRP) began coordinated production of scenario information for use across a suite of USGCRP activities. These have been implemented in the 4th National Climate Assessment (NCA4), the Climate Science Special Report and the Climate Resilience Toolkit (CRT), all of which are intended to help better organize, summarize, and communicate science to decision-makers as they think about our future. First, USGCRP introduced and implemented an explicit risk-framing approach across the entire scenario enterprise to encourage exploration of tail risks. A suite of scenario products was developed framed around three simplified storylines: `Lower', `Higher', and `Upper Bound' departures from current baselines. Second, USGCRP developed future climate information for the U.S. using Representative Concentration Pathway (RCP) 8.5 and RCP 4.5, including a weighted mean of Global Climate Models and adoption of an improved statistical downscaling approach across USGCRP products. Additional variables were derived from the downscaled parameters for use across USGCRP reports and in the CRT's Climate Explorer tool. Third, and given the need to address other tightly-coupled global changes in a more integrated way, a set of population, housing density, and impervious surface projections were developed based on global scenarios. In addition, USGCRP and the National Ocean Council developed scenarios of future sea-level rise and coastal-flood hazard for the U.S. and integrated them into existing Federal capabilities to support preparedness planning. To better convey these scenario components, next steps include capability for dynamic interaction between NCA4 products and CRT to permit users to explore and customize relevant information for their decision at spatial scales that matter to them, as well as links to more in-depth CRT content.

Water Exploration: An Online High School Water Resource Education Program

NASA Astrophysics Data System (ADS)

Ellins, K. K.; McCall, L. R.; Amos, S.; McGowan, R. F.; Mote, A.; Negrito, K.; Paloski, B.; Ryan, C.; Cameron, B.

2010-12-01

The Institute for Geophysics at The University of Texas at Austin and 4empowerment.com, a Texas-based for-profit educational enterprise, teamed up with the Texas Water Development Board to develop and implement a Web-based water resources education program for Texas high school students. The program, Water Exploration uses a project-based learning approach called the Legacy Cycle model to permit students to conduct research and build an understanding about water science and critical water-related issues, using the Internet and computer technology. The three Legacy Cycle modules in the Water Exploration curriculum are: Water Basics, Water-Earth Dynamics and People Need Water. Within each Legacy Cycle there are three different challenges, or instructional modules, laid out as projects with clearly stated goals for students to carry out. Each challenge address themes that map to the water-related “Big Ideas” and supporting concepts found in the new Earth Science Literacy Principles: The Big Ideas and Supporting Concepts of Earth Science. As students work through a challenge they follow a series of steps, each of which is associated (i.e., linked online) with a manageable number of corresponding, high quality, research-based learning activities and Internet resources, including scholarly articles, cyber tools, and visualizations intended to enhance understanding of the concepts presented. The culmination of each challenge is a set of “Go Public” products that are the students’ answers to the challenge and which serve as the final assessment for the challenge. The “Go Public” products are posted to a collaborative workspace on the Internet as the “legacy” of the students’ work, thereby allowing subsequent groups of students who take the challenge to add new products. Twenty-two science educators have been trained on the implementation of the Water Exploration curriculum. A graduate student pursuing a master’s degree in science education through The University of Texas’ UTEACH program is conducting research to track the teachers’ implementation of Water Exploration and assess their comfort with cyber-education through classroom observations, students and teacher surveys, and evaluation of students’ “Go Public” products.

Characterizing the development of sectoral gross domestic product composition.

PubMed

Lutz, Raphael; Spies, Michael; Reusser, Dominik E; Kropp, Jürgen P; Rybski, Diego

2013-07-01

We consider the sectoral composition of a country's gross domestic product (GDP), i.e., the partitioning into agrarian, industrial, and service sectors. Exploring a simple system of differential equations, we characterize the transfer of GDP shares between the sectors in the course of economic development. The model fits for the majority of countries providing four country-specific parameters. Relating the agrarian with the industrial sector, a data collapse over all countries and all years supports the applicability of our approach. Depending on the parameter ranges, country development exhibits different transfer properties. Most countries follow three of eight characteristic paths. The types are not random but show distinct geographic and development patterns.

Characterizing the development of sectoral gross domestic product composition

NASA Astrophysics Data System (ADS)

Lutz, Raphael; Spies, Michael; Reusser, Dominik E.; Kropp, Jürgen P.; Rybski, Diego

2013-07-01

We consider the sectoral composition of a country's gross domestic product (GDP), i.e., the partitioning into agrarian, industrial, and service sectors. Exploring a simple system of differential equations, we characterize the transfer of GDP shares between the sectors in the course of economic development. The model fits for the majority of countries providing four country-specific parameters. Relating the agrarian with the industrial sector, a data collapse over all countries and all years supports the applicability of our approach. Depending on the parameter ranges, country development exhibits different transfer properties. Most countries follow three of eight characteristic paths. The types are not random but show distinct geographic and development patterns.

Virtual Planetary Analysis Environment for Remote Science

NASA Technical Reports Server (NTRS)

Keely, Leslie; Beyer, Ross; Edwards. Laurence; Lees, David

2009-01-01

All of the data for NASA's current planetary missions and most data for field experiments are collected via orbiting spacecraft, aircraft, and robotic explorers. Mission scientists are unable to employ traditional field methods when operating remotely. We have developed a virtual exploration tool for remote sites with data analysis capabilities that extend human perception quantitatively and qualitatively. Scientists and mission engineers can use it to explore a realistic representation of a remote site. It also provides software tools to "touch" and "measure" remote sites with an immediacy that boosts scientific productivity and is essential for mission operations.

OBPR Product Lines, Human Research Initiative, and Physics Roadmap for Exploration

NASA Technical Reports Server (NTRS)

Israelsson, Ulf

2004-01-01

The pace of change has increased at NASA. OBPR s focus is now on the Human interface as it relates to the new Exploration vision. The fundamental physics community must demonstrate how we can contribute. Many opportunities exist for physicists to participate in addressing NASA's cross-disciplinary exploration challenges: a) Physicists can contribute to elucidating basic operating principles for complex biological systems; b) Physics technologies can contribute to developing miniature sensors and systems required for manned missions to Mars. NASA Codes other than OBPR may be viable sources of funding for physics research.

Exploring Digisonde Ionogram Data with SAO-X and DIDBase

NASA Astrophysics Data System (ADS)

Khmyrov, Grigori M.; Galkin, Ivan A.; Kozlov, Alexander V.; Reinisch, Bodo W.; McElroy, Jonathan; Dozois, Claude

2008-02-01

A comprehensive suite of software tools for ionogram data analysis and archiving has been developed at UMLCAR to support the exploration of raw and processed data from the worldwide network of digisondes in a low-latency, user-friendly environment. Paired with the remotely accessible Digital Ionogram Data Base (DIDBase), the SAO Explorer software serves as an example of how an academic institution conscientiously manages its resident data archive while local experts continue to work on design of new and improved data products, all in the name of free public access to the full roster of acquired ionospheric sounding data.

Function as a Determinant of Speech Production--Implications for Language Development in Schools.

ERIC Educational Resources Information Center

Skull, John

The function of speech and its implications for studying, understanding, and promoting language development are explored in this paper. Function is considered to be the purpose of the speaker when speaking, variously termed context of situation, situation, context, circumstance, or mode. It is noted that very few studies of speech and speech…

Leapfrogging Over the Status Quo: E-Learning and the Challenge of Adult Literacy.

ERIC Educational Resources Information Center

McCain, Mary

E-learning's potential for responding to the challenges of adult literacy was explored through a review of research and input from program managers, developers, and funders. The study identified adult literacy e-learning products, programs, and resources that are available or in development. Challenges to greater use of technology in adult…

Exploring Remote Sensing Products Online with Giovanni for Studying Urbanization

NASA Technical Reports Server (NTRS)

Shen, Suhung; Leptoukh, Gregory G.; Gerasimov, Irina; Kempler, Steve

2012-01-01

Recently, a Large amount of MODIS land products at multi-spatial resolutions have been integrated into the online system, Giovanni, to support studies on land cover and land use changes focused on Northern Eurasia and Monsoon Asia regions. Giovanni (Goddard Interactive Online Visualization ANd aNalysis Infrastructure) is a Web-based application developed by the NASA Goddard Earth Sciences Data and Information Services Center (GES-DISC) providing a simple and intuitive way to visualize, analyze, and access Earth science remotely-sensed and modeled data. The customized Giovanni Web portals (Giovanni-NEESPI and Giovanni-MAIRS) are created to integrate land, atmospheric, cryospheric, and social products, that enable researchers to do quick exploration and basic analyses of land surface changes and their relationships to climate at global and regional scales. This presentation documents MODIS land surface products in Giovanni system. As examples, images and statistical analysis results on land surface and local climate changes associated with urbanization over Yangtze River Delta region, China, using data in Giovanni are shown.

Investigating Pre-service Science Teachers' Developing Professional Knowledge Through the Lens of Differentiated Instruction

NASA Astrophysics Data System (ADS)

Goodnough, Karen

2010-03-01

In this study, the author implemented a problem-based learning (PBL) experience that allowed students in an advanced science methodology course to explore differentiated instruction. Through working systematically in small, collaborative groups, students explored the nature of differentiated instruction. The objective of the study was to examine pre-service teachers’ developing conceptions of differentiated instruction (DI) as a way to teach for diversity. The author adopted action research as a strategy to explore students’ perceptions of DI in the context of science teaching and learning. Several data collection methods and sources were adopted in the study, including student-generated products, student interviews, classroom observation, and journal writing. Outcomes report on students’ perceptions of both the potential and challenges associated with adopting a DI approach to science teaching and learning.

Additive Layer Manufacturing for Launcher's Applications

NASA Astrophysics Data System (ADS)

Vilanova, J.; Romera, P.; Lasagni, F.; Zorrilla, A.; Perinan, A.

2014-06-01

In the next years the European space industry has the challenge of maintaining its competitiveness in launch vehicles (LV) production, due to the growth of competition worldwide. It has to assure its position developing new applied technologies. In this field the effort is focussed on the production of short series of customized products, like payloads, flight components or launcher parts. ALM (Additive Layer Manufacturing) could be a powerful tool that offers new competitiveness factors for this industry, comprising a set of emerging technologies that are becoming a competitor to forming, casting and machining as well as being utilised directly as a complementary alternative.Originally used for prototypes and models, now ALM becomes a very useful technology capable to fabricate functional parts for the space industrial sector. Its demands on rapid technologies are different to "earth" industries, and they aren't so easily satisfied because space is a field with different requirements depending on its application: launchers, reusable vehicles, satellites, probes, low gravity researches, manned spacecraft, or even moon and planetary exploration.This paper reports on the ALM potential applications, under ESA requirements, exploring the challenges and possibilities for its use in the launchers market, trying to answer two basic questions: the first one, whether ALM is a mature technology to be ready for its use as flight hardware; and the second one, if it can be used to reduce the product cycle, and consequently, the development, production and operational costs.

Hypermedia and visual technology

NASA Technical Reports Server (NTRS)

Walker, Lloyd

1990-01-01

Applications of a codified professional practice that uses visual representations of the thoughts and ideas of a working group are reported in order to improve productivity, problem solving, and innovation. This visual technology process was developed under the auspices of General Foods as part of a multi-year study. The study resulted in the validation of this professional service as a way to use art and design to facilitate productivity and innovation and to define new opportunities. It was also used by NASA for planning Lunar/Mars exploration and by other companies for general business and advanced strategic planning, developing new product concepts, and litigation support. General Foods has continued to use the service for packaging innovation studies.

Waulsortian mound development in Warsaw at Broughton field, Ill.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whitaker, S.T.

1995-04-17

Oil production in the Lower Mississippian Ullin (Warsaw) limestone was first established in Illinois over 40 years ago. Exploration for hydrocarbons in this zone, however, was limited until recently due to a lack of a suitable explanation for reservoir development in this interval. The theory that Waulsortian mound development may explain many of these reservoirs was first presented in 1990. Research effort led by Zakaria Lasemi at the Illinois State Geological Survey has since established an excellent model for the generation of these bioherms. Lasemi performed numerous examinations of outcrops, cores, and well cuttings to develop his theory on themore » development and evolution of these biohermal features. This article presents an application of Lasemi`s model to an oil field in the Illinois basin. Similar applications could improve exploration and development success in Warsaw reservoirs.« less

Etude d'integration fonctionnelle du cycle de developpement des produits et des communautes de pratique virtuelles

NASA Astrophysics Data System (ADS)

Doumit, Nancy

Product development, subject to time constraints and system complexity, needs synchronous communication between different disciplines and locations in order to enable knowledge sharing. Being well supported, informal information flow increases productivity during product realization. Therefore, manufacturing industries are exploring the use of Enterprise Social Media (ESM) functionalities. This thesis explores the functional integration of formal information technologies such as Product Lifecycle Management (PLM) software with informal technologies as ESM through an industrial case study. Reviewing literature, the candidate has identified a gap between Virtual Communities of Practice (VCoP) and product development, as well as the correlation of PLM solutions and noncontrolled ESM in the aerospace industry. In order to disseminate a descriptive study of the current collaboration status, the author has undertaken online surveys for geodistant employees of the same department, semi-structured interviews and research among existing documentations. Subsequently, a Quality Functional Analysis is performed via two modified House of Quality matrices (PLM and ESM) to assign a convenient support for information transfer independently of its content maturity. Users' needs are categorized, and for each category a choice of platform is made with further recommendation regarding the use of the function or the need of human intervention. VCoP form an integrated part of the solution where employees support the technical content. Thus, essential roles and responsibilities are presented to maintain existing CoP and develop new ones. Finally, the candidate presents the limits of this research, gives recommendations for the manufacturing industry and suggests potential continuation of this study using PLM 2.0 with noncontrolled ESM tools.

Healthy casetas: A potential strategy to improve the food environment in low-income schools to reduce obesity in children in Guatemala City.

PubMed

Pehlke, Elisa L; Letona, Paola; Ramirez-Zea, Manuel; Gittelsohn, Joel

2016-01-01

Developing countries have undergone transitions driven by globalization and development, accelerating increases in prevalence of overweight and obesity among children. Schools have been identified as effective settings for interventions that target children's dietary behaviors. In Guatemala, public schools commonly have food kiosks (Casetas) that sell products to children. From July through October 2013, observations during recess, in-depth interviews with school principals (n = 4) and caseta vendors (n = 4), and focus groups with children (n = 48) were conducted. This article explores products available to children at casetas. Factors that affect what casetas offer include regulations and enforcement, vendor investment and earnings, vendor resources, product demand, pricing, and children's preferences. These factors influence the products that are available and children's tendency to purchase them. Potential strategies for improvement include healthy food preparation, price manipulation and promotions, raffles and games to encourage healthier choices, and policy to push toward development of healthier products.

LSSA (Low-cost Silicon Solar Array) project

NASA Technical Reports Server (NTRS)

1976-01-01

Methods are explored for economically generating electrical power to meet future requirements. The Low-Cost Silicon Solar Array Project (LSSA) was established to reduce the price of solar arrays by improving manufacturing technology, adapting mass production techniques, and promoting user acceptance. The new manufacturing technology includes the consideration of new silicon refinement processes, silicon sheet growth techniques, encapsulants, and automated assembly production being developed under contract by industries and universities.

Spill Prevention, Control, and Countermeasure (SPCC) for the Upstream (Oil Exploration and Production) Sector

EPA Pesticide Factsheets

The SPCC rule requires facilities to develop, maintain, and implement an oil spill prevention plan, called an SPCC Plan. These plans help facilities prevent oil spill, as well as control a spill should one occur.

Polymerized and functionalized triglycerides

USDA-ARS?s Scientific Manuscript database

Plant oils are useful sustainable raw materials for the development of new chemical products. As part of our research emphasis in sustainability and green polymer chemistry, we have explored a new method for polymerizing epoxidized triglycerides with the use of fluorosulfonic acid. Depending on the ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shattan, Michael; Stowe, Ashley; McIntosh, Kathryn

Explore feasibility of portable LIBS and micro-XRF systems as methods of field screening for real debris; Develop a LIBS Capability to rapidly screen beads for production quality control; Complete 3D elemental mapping of surrogate debris to determine uranium and other elemental migration patterns during debris formation

30 CFR 250.202 - What criteria must the Exploration Plan (EP), Development and Production Plan (DPP), or...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Section 250.202 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT...; and (e) Does not cause undue or serious harm or damage to the human, marine, or coastal environment. ...

14 CFR 1266.104 - Cross-waiver of liability for launch agreements for science or space exploration activities...

Code of Federal Regulations, 2010 CFR

2010-01-01

... activities related to ground support, test, training, simulation, or guidance and control equipment and... are conducted on return from space to develop further a payload's product or process for use other...

How can a policy foster local pharmaceutical production and still protect public health? Lessons from the health-industry complex in Brazil.

PubMed

da Fonseca, Elize Massard

2018-04-01

The global health community is increasingly advocating for the local production of pharmaceuticals in developing countries as a way to promote technology transfer, capacity building and improve access to medicines. However, efforts to advance drug manufacturing in these countries revive an old dilemma of fostering technological development versus granting access to social services, such as healthcare. This paper explores the case of Brazil, a country that has developed large-scale health-inspired industrial policies, but is, yet, little understood. Brazil's experience suggests that progressive healthcare bureaucrats can create innovative practices for technology and knowledge transfers. It also demonstrates that highly competitive pharmaceutical firms can collaborate with each other, if a government provides them the right incentives. Reforming regulatory policies is crucial for guaranteeing high-quality products in developing countries, but governments must play a crucial role in supporting local firms to adapt to these regulations. These findings send a strong message to global health policymakers and practitioners on the conditions to create a suitable environment for local production of medical products.

Microgravity, Mesh-Crawling Legged Robots

NASA Technical Reports Server (NTRS)

Behar, Alberto; Marzwell, Neville; Matthews, Jaret; Richardson, Krandalyn; Wall, Jonathan; Poole, Michael; Foor, David; Rodgers, Damian

2008-01-01

The design, fabrication, and microgravity flight-testing are part of a continuing development of palm-sized mobile robots that resemble spiders (except that they have six legs apiece, whereas a spider has eight legs). Denoted SpiderBots (see figure), they are prototypes of proposed product line of relatively inexpensive walking robots that could be deployed in large numbers to function cooperatively in construction, repair, exploration, search, and rescue activities in connection with exploration of outer space and remote planets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGettigan, C.K.; Hunt, D.G.

Colombia, where petroleum development began in 1908, is still yielding giant and supergiant discoveries. Recent successes result from improvements in exploration technology, in infrastructure, and in terms of participation offered by the Colombian government. Colombia has 13 sedimentary basins covering an area of 700,000 sq km out of a total country area of 1,350,000 sq km, including the continental shelf. This article highlights four of the seven basins currently productive in Colombia, providing an overview of geology and recent exploration activity.

Overview of Proposed ISRU Technology Development

NASA Technical Reports Server (NTRS)

Linne, Diane; Sanders, Jerry; Starr, Stan; Suzuki, Nantel; O'Malley, Terry

2016-01-01

ISRU involves any hardware or operation that harnesses and utilizes in-situ resources (natural and discarded) to create products and services for robotic and human exploration: Assessment of physical, mineral chemical, and volatile water resources, terrain, geology, and environment (orbital and local). Production of replacement parts, complex products, machines, and integrated systems from feedstock derived from one or more processed resources. Civil engineering, infrastructure emplacement, and structure construction using materials produced from in situ resources. Radiation shields, landing pads, roads, berms, habitats, etc. Generation and storage of electrical, thermal, and chemical energy with in situ derived materials. Solar arrays, thermal wadis, chemical batteries, etc. ISRU is a disruptive capability: Enables more affordable exploration than todays paradigm. Allows more sustainable architectures to be developed. Understand the ripple effect in the other Exploration Elements: MAV: propellant selection, higher rendezvous altitude (higher DV capable with ISRU propellants). EDL: significantly reduces required landed mass. Life Support: reduce amount of ECLSS closure, reduce trash mass carried through propulsive maneuvers. Power: ISRU drives electrical requirements, reactant and regeneration for fuel cells for landers, rovers, and habitat backup. Every Exploration Element except ISRU has some flight heritage (power, propulsion, habitats, landers, life support, etc.) ISRU will require a flight demonstration mission on Mars before it will be included in the critical path. Mission needs to be concluded at least 10 years before first human landed mission to ensure lessons learned can be incorporated into final design. ISRU Formulation team has generated a (still incomplete) list of over 75 technical questions on more than 40 components and subsystems that need to be answered before the right ISRU system will be ready for this flight demo.

Innovation and performance: The case of the upstream petroleum sector

NASA Astrophysics Data System (ADS)

Persaud, A. C. Jai

This thesis investigates innovation in the upstream crude oil and natural gas sector, a strategic part of the Canadian economy and a vital industry for North American energy trade and security. Significant interest exists in understanding innovation in this sector from a private and public policy perspective. Interest in the sector has intensified recently due to concerns about world oil supply, Canada's oil sands development, and the potential that Canada may become an "energy superpower." The study examines the factors that drive companies involved in exploration, development, and production in the upstream petroleum sector to innovate and the impact of their innovation activities through major technologies on their performance. The thesis focuses on process innovation, which involves the adoption of new or significantly improved production processes, and is distinct from product innovation, which is based on the development and commercialization of a product with improved product characteristics to deliver new services to the consumer. The thesis provides a comprehensive review of the literature and develops an investigative model framework to examine the drivers of innovation and the impact of innovation on performance in the upstream petroleum sector. The research employs a survey questionnaire that was developed to obtain data and information, which was missing in the literature or not publicly available to test key relationships of innovation and performance indicators. In addition to the survey questionnaire, a number of knowledgeable experts in the industry were also interviewed. A total of 68 respondents completed the survey questionnaire, accounting for 40 percent of the firms in the industry. This percentage goes up to over 50 percent when account is taken of extremely small firms who could not fill out the survey. Further, the 68 respondents account for most of the industry revenues, production, and employment. The respondents include most of the key explorers, developers, and producers as well as the owners of the major projects and oil sands developments. Almost all firms in the industry with revenues above $1B with employees above 1000 responded to the survey. As well, many companies have joint project arrangements and farm-in agreements with other companies in the industry. Hence, this survey is considered highly representative of the industry. Industry associations were very helpful in providing advice, and in endorsing the circulation of the questionnaire. The results show that the sector relies more heavily on acquiring advanced machinery and equipment, processes and other external knowledge than on internal R&D. Advanced machinery and equipment includes embedded R&D. 3D and 4D seismic stand out as the most relied upon in exploration, horizontal wells in development activities, and field recovery in production. Increasing productive capacity, reducing costs and reducing environmental impact are the three main drivers of innovation. Collaboration is important to the sector and agreements with competitors and suppliers are ranked as most important. The main reason for collaboration is to gain access to external knowledge. Government tax incentives (e.g., the Scientific Research and Experimental Development) (SR&ED) tax credit and its fiscal framework are important in spurring R&D. Fiscal policies, on the other hand, are more important for acquiring advanced machinery and equipment, advanced processes, and other external knowledge. The study has several broad implications with respect to the application of technologies: (1) Without the adoption of major technologies, costs would have been substantially higher and productive capacity and productivity much lower. This study also contributes to the view that resources should not be treated as a fixed stock but as flow which can be improved. (2) The environment is an important driver of innovation, particularly environmental regulation. Providing the right mix of regulation and leaving firms to undertake innovation may result in favorable impacts. (3) Increasing R&D tax incentives may not necessarily have an increased direct impact on innovation in exploration, development, and production compared to other types of firms in the economy. The innovation impact, however, may be increased indirectly through the acquisition of imbedded R&D. (4) Collaboration among firms and with government can be useful to address specific industry problems. Government's role will continue to be important in developing pre-competitive technologies for achieving public policy goals. (5) Technology can play an important role in Canada becoming an "energy superpower" and, more importantly, a "clean energy superpower" and contributing to energy security in Canada and in the U.S. Discussions with industry officials suggest that water availability, energy availability for oil sands development, skill shortages, and super depletion allowances for CO2 sequestration are important issues and challenges for the industry. These areas warrant investigation. In addition to these issues, this thesis concludes by making suggestions for further research. (Abstract shortened by UMI.)

Hunting oil between elephants in Block 34/7 on the Norwegian shelf

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvsborg, A.; Nybakken, S.; Solli, T.

Block 34/7 is located east of the Statfjord field producing since 1979, and north of Gullfaks field, producing since 1986. Snorre field in the block should begin production in 1992. These three fields have more than 11 billion bbl in place and 5 billion bbl recoverable reserves. A heavy exploration program is done parallel to field development studies. The exploration activity is due to approaching relinquishment and securing tie-in to existing infrastructure. Because of extensive production facilities, small reserves can be used and all traps are now mapped and risk evaluated. So far, four discoveries have been made outside themore » Snorre field: Statfjord Oest Snorre Vest, C, and B. Estimated recoverable reserves are 400 million bbl. However, additional prospects could more than double these reserves. Exploration started with conventional structural traps. The two latest discoveries are pinch-out traps, and the next to be tested by wells are sealing fault traps. The East flank is a separate province downfaulted 2 km with several structures depending on sealing faults. New stratigraphy will be tested by the next well which is deviated to penetrate possible Lower Cretaceous and Upper Jurassic reservoir before reaching the main goal, which is the Brent reservoir. The result of this well could be very important for the opening of possible new play concepts in the northern North Sea. A sealing fault trap with Brent reservoir on the Tampen Spur will be tested by a well in 1990. Exploration is, however, in progress at several other stratigraphic levels within Tertiary, Upper and Lower Cretaceous, and other Upper Jurassic reservoirs where the possibilities for stratigraphic traps exist. These will be tested during next year's exploration program to secure potential reserves for field development at low production cost. Today, the minimum economic recoverable reserves in a prospect are 5-10 million bbl.« less

Who am I? Key influences on the formation of academic identity within a faculty development program.

PubMed

Lieff, Susan; Baker, Lindsay; Mori, Brenda; Egan-Lee, Eileen; Chin, Kevin; Reeves, Scott

2012-01-01

Professional identity encompasses how individuals understand themselves, interpret experiences, present themselves, wish to be perceived, and are recognized by the broader professional community. For health professional and health science educators, their 'academic' professional identity is situated within their academic community and plays an integral role in their well being and productivity. This study aims to explore factors that contribute to the formation and growth of academic identity (AI) within the context of a longitudinal faculty development program. Using a qualitative case study approach, data from three cohorts of a 2-year faculty development program were explored and analyzed for emerging issues and themes related to AI. Factors salient to the formation of AI were grouped into three major domains: personal (cognitive and emotional factors unique to each individual); relational (connections and interactions with others); and contextual (the program itself and external work environments). Faculty development initiatives not only aim to develop knowledge, skills, and attitudes, but also contribute to the formation of academic identities in a number of different ways. Facilitating the growth of AI has the potential to increase faculty motivation, satisfaction, and productivity. Faculty developers need to be mindful of factors within the personal, relational, and contextual domains when considering issues of program design and implementation.

NASA's Solar System Treks: Online Portals for Planetary Mapping and Modeling

NASA Technical Reports Server (NTRS)

Day, Brian

2017-01-01

NASA's Solar System Treks are a suite of web-based of lunar and planetary mapping and modeling portals providing interactive visualization and analysis tools enabling mission planners, planetary scientists, students, and the general public to access mapped lunar data products from past and current missions for the Moon, Mars, Vesta, and more. New portals for additional planetary bodies are being planned. This presentation will recap significant enhancements to these toolsets during the past year and look ahead to future features and releases. Moon Trek is a new portal replacing its predecessor, the Lunar Mapping and Modeling Portal (LMMP), that significantly upgrades and builds upon the capabilities of LMMP. It features greatly improved navigation, 3D visualization, fly-overs, performance, and reliability. Additional data products and tools continue to be added. These include both generalized products as well as polar data products specifically targeting potential sites for NASA's Resource Prospector mission as well as for missions being planned by NASA's international partners. The latest release of Mars Trek includes new tools and data products requested by NASA's Planetary Science Division to support site selection and analysis for Mars Human Landing Exploration Zone Sites. Also being given very high priority by NASA Headquarters is Mars Trek's use as a means to directly involve the public in upcoming missions, letting them explore the areas the agency is focusing upon, understand what makes these sites so fascinating, follow the selection process, and get caught up in the excitement of exploring Mars. Phobos Trek, the latest effort in the Solar System Treks suite, is being developed in coordination with the International Phobos/Deimos Landing Site Working Group, with landing site selection and analysis for JAXA's MMX (Martian Moons eXploration) mission as a primary driver.

APPLICATION OF AUDIO-MAGNETOTELLURIC SURVEYS ON SAO MIGUEL ISLAND, AZORES PORTUGAL.

USGS Publications Warehouse

Hoover, Donald; Rodrigues Da Silva, A.; Pierce, Herbert A.; Amaral, Roberto

1984-01-01

Geothermal exploration and development has been under way on Sao Miguel Island, Azores since 1975. This work had been restricted to the Fogo volcano, one of three dormant silicic volcanic centers on the island. The USGS in 1982 and 1983 conducted reconnaissance natural-source audio-magnetotelluric (AMT) surveys of all three silicic centers to evaluate the potential for geothermal systems at each and to demonstrate the utility of the method in areas of difficult terrain. Results on Fogo showed a low resistivity trend extending from the present production area upslope to the caldera boundary. The upper part of this trend is the upwelling zone of a thermal plume which supplies the production area. Further exploration and drilling are now planned for this area.

Creating a winning organizational culture.

PubMed

Campbell, Robert James

2009-01-01

This article explores the idea of how to create a winning organizational culture. By definition, a winning organizational culture is one that is able to make current innovations stick, while continuously changing based on the demands of the marketplace. More importantly, the article explores the notion that a winning organizational culture can have a profound impact on the conscious of the workforce, helping each individual to become a better, more productive person, who provides important services and products to the community. To form a basis toward defining the structure of what a winning organization culture looks like, 4 experts were asked 12 questions related to the development of an organizational culture. Three of the experts have worked intimately within the health care industry, while a fourth has been charged with turning around an organization that has had a losing culture for 17 years. The article provides insight into the role that values, norms, goals, leadership style, familiarity, and hiring practices play in developing a winning organizational culture. The article also emphasizes the important role that leaders perform in developing an organizational culture.

Relationship between perceived work ability and productivity loss.

PubMed

Vänni, Kimmo; Virtanen, Pekka; Luukkaala, Tiina; Nygård, Clas-Håkan

2012-01-01

This paper presents an approach to assessing presenteeism (on-the-job productivity loss) that is related to perceived work ability. The aim of this explorative research was to find out if perceived work ability could be a robust indicator, interchangeable with presenteeism, in Finnish food industry organizations. The developed approach was based on existing presenteeism research as well as on register and survey data. The approach demonstrates that one step downward on the 10-point perceived work ability scale theoretically reduces employees' on-the-job productivity by ˜5 percentage points. At the company level, on-the-job productivity loss was 3.7% (mdn 0), while sickness absence was 5.0% (mdn 2.2). The probability of productivity loss among factory workers was fourfold compared to women in office work. The developed approach makes it possible to assess perceived productivity loss at the level of an individual and an organization. Perceived work ability may, in fact, be a robust indicator for assessing perceived productivity loss.

75 FR 54300 - Energy and Infrastructure Mission to Saudi Arabia

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-07

...) and communication products and services to potential buyers and allow them to explore new business... to discuss industry developments, opportunities, and sales strategies. Commercial Setting Saudi... key U.S. Government and corporate officials. Participants will also take part in business matchmaking...

Using Bayesian Belief Networks to Explore the Effects of Nitrogen Inputs on Wetland Ecosystem Services

EPA Science Inventory

Increased reactive nitrogen (Nr) inputs to freshwater wetlands resulting from infrastructure development due to population growth along with intensive agricultural practices associated with food production can threaten regulating (i.e. climate change, water purification, and wast...

30 CFR 250.1602 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1602 Applicability. (a) The requirements of this subpart P are applicable to all exploration, development, and production operations under an...

43 CFR 3480.0-4 - Scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... operations for the exploration, development, and production of Federal coal under Federal coal leases... licenses for unleased Federal coal are codified at 43 CFR part 3410. Until final rulemaking is promulgated... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT...

43 CFR 3480.0-4 - Scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... operations for the exploration, development, and production of Federal coal under Federal coal leases... licenses for unleased Federal coal are codified at 43 CFR part 3410. Until final rulemaking is promulgated... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT...

43 CFR 3480.0-4 - Scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... operations for the exploration, development, and production of Federal coal under Federal coal leases... licenses for unleased Federal coal are codified at 43 CFR part 3410. Until final rulemaking is promulgated... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT...

43 CFR 3480.0-4 - Scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... operations for the exploration, development, and production of Federal coal under Federal coal leases... licenses for unleased Federal coal are codified at 43 CFR part 3410. Until final rulemaking is promulgated... Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT...

Perspectives on Evaluation, Linkage and Program Improvement.

ERIC Educational Resources Information Center

Bank, Adrianne; And Others

Actual and potential relationships between evaluators and linkers--curriculum or management specialists who disseminate the products of evaluation to school districts--were explored. Evaluation and linkage evolved as distinct educational occupations, stimulated by federal involvement in research, development, and school improvement since the early…

Functional food. Product development, marketing and consumer acceptance--a review.

PubMed

Siró, István; Kápolna, Emese; Kápolna, Beáta; Lugasi, Andrea

2008-11-01

It was mainly the advances in understanding the relationship between nutrition and health that resulted in the development of the concept of functional foods, which means a practical and new approach to achieve optimal health status by promoting the state of well-being and possibly reducing the risk of disease. Functional foods are found virtually in all food categories, however products are not homogeneously scattered over all segments of the growing market. The development and commerce of these products is rather complex, expensive and risky, as special requirements should be answered. Besides potential technological obstacles, legislative aspects, as well as consumer demands need to be taken into consideration when developing functional food. In particular, consumer acceptance has been recognized as a key factor to successfully negotiate market opportunities. This paper offers a brief overview of the current functional food market situation in USA, Japan and some European countries completed with some comments on functional food future potential. It explores the main challenges of such product development focusing on the different factors determining the acceptance of functional food. Furthermore it discusses some prominent types of these food products currently on the market.

Welcoming and Restoring, Dwelling and Sending: Creating a Space for Hospitality in Faculty Development

ERIC Educational Resources Information Center

Larson, Marion H.

2009-01-01

Parker Palmer's (1983) often-quoted definition of teaching--"To teach is to create a space in which obedience to truth is practiced"--can be applied productively to work in faculty development. Exploring this notion is enhanced by the theological literature in hospitality, which can be viewed through Amy Oden's (2001) discussion of four movements…

Coordinated Health and Human Resources Development: Report of a WHO Study Group. Technical Report Series No. 801.

ERIC Educational Resources Information Center

World Health Organization, Geneva (Switzerland).

This report explores the theory and practice of coordinated health and human resources development as a concept that can help guard against the production of inappropriate categories or numbers of health personnel. The report concentrates of what can be done to make education and training programs more directly responsive to the priority needs in…

"Your Mum and Dad Can't Teach You!": Constraints on Agency among Rural Learners of English in the Developing World

ERIC Educational Resources Information Center

Lamb, Martin

2013-01-01

Learning outcomes are always the product of the interaction between individual learner agency and social structures. Recently concern has been expressed about unequal access to English, recognised as an important resource for social advancement, for rural populations in developing countries. This paper explores this issue by focusing on one…

Arab oil and gas directory 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-01-01

The directory provides detailed statistics and information on aspects of oil and gas production, exploration and developments in the 24 Arab countries of the Middle East and North Africa and in Iran. It includes the texts of relevant new laws and official documents, official surveys, current projects and developments, up-to-date statistics covering OPEC and OAPEC member countries, and has 26 maps.

In Situ Manufacturing of Plastics and Composites to Support H&R Exploration

NASA Astrophysics Data System (ADS)

Carranza, Susana; Makel, Darby B.; Blizman, Brandon

2006-01-01

With the new direction of NASA to emphasize the exploration of the Moon, Mars and beyond, quick development and demonstration of efficient systems for In Situ Resources Utilization (ISRU) is more critical and timely than ever before. Beyond the production of life support consumables or propellants, long term missions will require much greater levels of utilization of indigenous resources, including fabrication of habitats, radiation shielding, and replacement parts and tools. This paper reports the development of a reactor system for the synthesis of polyethylene from carbon dioxide and water. One technology commonly found in most NASA In Situ Resources Utilization scenarios is the use of the Sabatier reaction and water electrolysis to produce methane and oxygen. The system presented uses methane and oxygen to produce ethylene, and subsequently ethylene is polymerized to produce polyethylene. The process selected enables the synthesis of high-density polyethylene suitable for the fabrication of many products for space exploration, including sheets, films, channels, etc, which can be used to construct extraterrestrial habitats, tools, replacement parts, etc. Conventional fabrication processes, such as extrusion and injection molding, which are used in the fabrication of polyethylene parts, can be adapted for space operation, making polyethylene a versatile feedstock for future in-situ manufacturing plants. Studies show that polyethylene is a very good radiation shield material, making it very suitable for construction of habitats, as well as incorporation in space suits. For the fabrication of massive structures, polyethylene can be combined with indigenous soil to maximize the use of unprocessed resources, either enclosed in channels, bags, etc., or compounded in varying proportions. The focus of this paper is to present current progress in the development of manufacturing systems and processes for the production of plastics and composites utilizing indigenous resources such as planetary atmosphere and soil.

Reducing Subjectivity in Geothermal Exploration Decision Making (Presentation); NREL(National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akar, S.; Young, K.

Geothermal exploration projects have a significant amount of risk associated with uncertainties encountered in the discovery of the geothermal resource. Two of the largest challenges for increased geothermal deployment are 1) understanding when and how to proceed in an exploration program, and 2) when to walk away from a site. Current methodologies for exploration decision-making are formulatedby subjective expert opinion which can be incorrectly biased by expertise (e.g. geochemistry, geophysics), geographic location of focus, and the assumed conceptual model. The aim of this project is to develop a methodology for more objective geothermal exploration decision making at a given location,more » including go/no-go decision points to help developers and investors decide when to give up on alocation. In this scope, two different approaches are investigated: 1) value of information analysis (VOIA) which is used for evaluating and quantifying the value of a data before they are purchased, and 2) enthalpy-based exploration targeting based on reservoir size, temperature gradient estimates, and internal rate of return (IRR). The first approach, VOIA, aims to identify the value of aparticular data when making decisions with an uncertain outcome. This approach targets the pre-drilling phase of exploration. These estimated VOIs are highly affected by the size of the project and still have a high degree of subjectivity in assignment of probabilities. The second approach, exploration targeting, is focused on decision making during the drilling phase. It starts with a basicgeothermal project definition that includes target and minimum required production capacity and initial budgeting for exploration phases. Then, it uses average temperature gradient, reservoir temperature estimates, and production capacity to define targets and go/no-go limits. The decision analysis in this approach is based on achieving a minimum IRR at each phase of the project. This secondapproach was determined to be less subjective, since numerical inputs come from the collected data. And it helps to facilitate communication between project managers and exploration geologists in making objective go/no-go decisions throughout the different project phases.« less

EVA Systems Technology Gaps and Priorities 2017

NASA Technical Reports Server (NTRS)

Johnson, Brian J.; Buffington, Jesse A.

2017-01-01

Performance of Extra-Vehicular Activities (EVA) has been and will continue to be a critical capability for human space flight. Human exploration missions beyond LEO will require EVA capability for either contingency or nominal activities to support mission objectives and reduce mission risk. EVA systems encompass a wide array of products across pressure suits, life support systems, EVA tools and unique spacecraft interface hardware (i.e. EVA Translation Paths and EVA Worksites). In a fiscally limited environment with evolving transportation and habitation options, it is paramount that the EVA community's strategic planning and architecture integration products be reviewed and vetted for traceability between the mission needs far into the future to the known technology and knowledge gaps to the current investments across EVA systems. To ascertain EVA technology and knowledge gaps many things need to be brought together, assessed and analyzed. This includes an understanding of the destination environments, various mission concept of operations, current state of the art of EVA systems, EVA operational lessons learned, and reference advanced capabilities. A combined assessment of these inputs should result in well-defined list of gaps. This list can then be prioritized depending on the mission need dates and time scale of the technology or knowledge gap closure plan. This paper will summarize the current state of EVA related technology and knowledge gaps derived from NASA's Exploration EVA Reference Architecture and Operations Concept products. By linking these products and articulating NASA's approach to strategic development for EVA across all credible destinations an EVA could be done in, the identification of these gaps is then used to illustrate the tactical and strategic planning for the EVA technology development portfolio. Finally, this paper illustrates the various "touch points" with other human exploration risk identification areas including human health and performance.

Petroleum geology of Choctaw County, Alabama

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myers, J.D.

The first commercial oil production in the State of Alabama was established in Choctaw County in 1944 when H.L. Hunt discovered Gilbertown field. Gilbertown produces oil from the Selma and Eutaw formations of Upper Cretaceous Age. During 1967, Toxey field was discovered by E.L. Erickson and Choctaw Ridge was discovered by C. Pruet and D. Hughes. These 2 discoveries initiated the successful Smackover oil exploration in Choctaw County which is continuing today. This study deals primarily with the petroleum geology of the Smackover Formation of Jurassic Age. The detailed stratigraphic and structural geology of several Smackover oil fields in Choctawmore » County is examined to illustrate geological concepts developed while exploring the Smackover. Factors influencing porosity development are emphasized and suggestions are made for future exploration in the Choctaw trend of Alabama.« less

Bio-mining the microbial treasures of the ocean: new natural products.

PubMed

Imhoff, Johannes F; Labes, Antje; Wiese, Jutta

2011-01-01

The biological resources of the oceans have been exploited since ancient human history, mainly by catching fish and harvesting algae. Research on natural products with special emphasis on marine animals and also algae during the last decades of the 20th century has revealed the importance of marine organisms as producers of substances useful for the treatment of human diseases. Though a large number of bioactive substances have been identified, some many years ago, only recently the first drugs from the oceans were approved. Quite astonishingly, the immense diversity of microbes in the marine environments and their almost untouched capacity to produce natural products and therefore the importance of microbes for marine biotechnology was realized on a broad basis by the scientific communities only recently. This has strengthened worldwide research activities dealing with the exploration of marine microorganisms for biotechnological applications, which comprise the production of bioactive compounds for pharmaceutical use, as well as the development of other valuable products, such as enzymes, nutraceuticals and cosmetics. While the focus in these fields was mainly on marine bacteria, also marine fungi now receive growing attention. Although culture-dependent studies continue to provide interesting new chemical structures with biological activities at a high rate and represent highly promising approaches for the search of new drugs, exploration and use of genomic and metagenomic resources are considered to further increase this potential. Many efforts are made for the sustainable exploration of marine microbial resources. Large culture collections specifically of marine bacteria and marine fungi are available. Compound libraries of marine natural products, even of highly purified substances, were established. The expectations into the commercial exploitation of marine microbial resources has given rise to numerous institutions worldwide, basic research facilities as well as companies. In Europe, recent activities have initiated a dynamic development in marine biotechnology, though concentrated efforts on marine natural product research are rare. One of these activities is represented by the Kieler Wirkstoff-Zentrum KiWiZ, which was founded in 2005 in Kiel (Germany). Copyright © 2011 Elsevier Inc. All rights reserved.

High Performance Processors for Space Environments: A Subproject of the NASA Exploration Missions Systems Directorate "Radiation Hardened Electronics for Space Environments" Technology Development Program

NASA Technical Reports Server (NTRS)

Johnson, M.; Label, K.; McCabe, J.; Powell, W.; Bolotin, G.; Kolawa, E.; Ng, T.; Hyde, D.

2007-01-01

Implementation of challenging Exploration Systems Missions Directorate objectives and strategies can be constrained by onboard computing capabilities and power efficiencies. The Radiation Hardened Electronics for Space Environments (RHESE) High Performance Processors for Space Environments project will address this challenge by significantly advancing the sustained throughput and processing efficiency of high-per$ormance radiation-hardened processors, targeting delivery of products by the end of FY12.

Comparative evaluation of solar, fission, fusion, and fossil energy resources. Part 5: Conclusions and recomendations

NASA Technical Reports Server (NTRS)

Williams, J. R.

1974-01-01

Air pollution resulting from the use of fossil fuels is discussed. Phenomena relating to the emission of CO2 such as the greenhouse effect and multiplier effect are explored. Particulate release is also discussed. The following recommendations are made for the elimination of fossil fuel combustion products in the United States: development of nuclear breeder reactors, use of solar energy systems, exploration of energy alternatives such as geothermal and fusion, and the substitution of coal for gas and oil use.

Scope of Algae as Third Generation Biofuels

PubMed Central

Behera, Shuvashish; Singh, Richa; Arora, Richa; Sharma, Nilesh Kumar; Shukla, Madhulika; Kumar, Sachin

2015-01-01

An initiative has been taken to develop different solid, liquid, and gaseous biofuels as the alternative energy resources. The current research and technology based on the third generation biofuels derived from algal biomass have been considered as the best alternative bioresource that avoids the disadvantages of first and second generation biofuels. Algal biomass has been investigated for the implementation of economic conversion processes producing different biofuels such as biodiesel, bioethanol, biogas, biohydrogen, and other valuable co-products. In the present review, the recent findings and advance developments in algal biomass for improved biofuel production have been explored. This review discusses about the importance of the algal cell contents, various strategies for product formation through various conversion technologies, and its future scope as an energy security. PMID:25717470

Libya: World Oil Report 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1991-08-01

This paper reports that Libya is moving forward with plans to sell most of its crude as refined products and should have the capacity to handle most of its production, about 1.3 million bpd, by the mid-90s. Production was increased after the Iraqi invasion of Kuwait, and peak capacity could be over 1.5 million bopd. Exploration pace is still increasing but U.S. sanctions have taken their toll. Gas projects are advancing as officials push to develop and utilize more domestic gas reserves. Libya has commissioned a new gas processing plant in Sahl gas field in Sirte basin and plans aremore » under way for development of Tahaddi field, Libya's largest gas field with 9 Tcf.« less

Recent advances and state-of-the-art strategies in strain and process engineering for biobutanol production by Clostridium acetobutylicum.

PubMed

Xue, Chuang; Zhao, Jingbo; Chen, Lijie; Yang, Shang-Tian; Bai, Fengwu

Butanol as an advanced biofuel has gained great attention due to its environmental benefits and superior properties compared to ethanol. However, the cost of biobutanol production via conventional acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum is not economically competitive, which has hampered its industrial application. The strain performance and downstream process greatly impact the economics of biobutanol production. Although various engineered strains with carefully orchestrated metabolic and sporulation-specific pathways have been developed, none of them is ideal for industrial biobutanol production. For further strain improvement, it is necessary to develop advanced genome editing tools and a deep understanding of cellular functioning of genes in metabolic and regulatory pathways. Processes with integrated product recovery can increase fermentation productivity by continuously removing inhibitory products while generating butanol (ABE) in a concentrated solution. In this review, we provide an overview of recent advances in C. acetobutylicum strain engineering and process development focusing on in situ product recovery. With deep understanding of systematic cellular bioinformatics, the exploration of state-of-the-art genome editing tools such as CRISPR-Cas for targeted gene knock-out and knock-in would play a vital role in Clostridium cell engineering for biobutanol production. Developing advanced hybrid separation processes for in situ butanol recovery, which will be discussed with a detailed comparison of advantages and disadvantages of various recovery techniques, is also imperative to the economical development of biobutanol. Copyright © 2017 Elsevier Inc. All rights reserved.

Integration of In-Situ Resource Utilization Into Lunar/Mars Exploration Through Field Analogs

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.; Larson, William E.

2010-01-01

The NASA project to develop In-Situ Resource Utilization (ISRU) technologies, in partnership with commercial and international collaborators, has achieved full system demonstrations of oxygen production using native regolith simulants. These demonstrations included robotic extraction of material from the terrain, sealed encapsulation of material in a pressurized reactor; chemical extraction of oxygen from the material in the form of water, and the electrolysis of water into oxygen and hydrogen for storage and reuse. These successes have provided growing confidence in the prospects of ISRU oxygen production as a credible source for critical mission consumables in preparation for and during crewed missions to the moon and other destinations. Other ISRU processes, especially relevant to early lunar exploration scenarios, have also been shown to be practical, including the extraction of subsurface volatiles, especially water, and the thermal processing of surface materials for civil engineering uses and for thermal energy storage. This paper describes these recent achievements and current NASA ISRU development and demonstration activity. The ability to extract and process resources at the site of exploration into useful products such as propellants, life support and power system consumables; and radiation and rocket exhaust plume debris shielding, known as In-Situ Resource Utilization or ISRU, has the potential to significantly reduce the launch mass, risk, and cost of robotic and human exploration of space. The incorporation of ISRU into missions can also significantly influence technology selection and system development in other areas such as power, life support, and propulsion. For example. the ability to extract or produce large amounts of oxygen and/or water in-situ could minimize the need to completely close life support air and water processing system cycles, change thermal and radiation protection of habitats, and influence propellant selection for ascent vehicles and surface propulsive hoppers. While concepts and even laboratory work on evaluating and developing ISRU techniques such as oxygen extraction from lunar regolith have been going on since before the Apollo 11 Moon landing, no ISRU system has ever flown in space, and only recently have ISRU technologies been developed at a scale and at a system level that is relevant to actual robotic and human mission applications. Because ISRU hardware and systems have never been demonstrated or utilized before on robotic or human missions, architecture and mission planners and surface system hardware developers are hesitant to rely on ISRU products and services that are critical to mission and system implementation success. To build confidence in ISRU systems for future missions and assess how ISRU systems can best influence and integrate with other surface system elements, NASA, with international partners, are performing analog field tests to understand how to take advantage of ISRU capabilities and benefits with the minimum of risk associated with introducing this game-changing approach to exploration. This paper will describe and review the results of four analog field tests (Moses Lake in 6/08, Mauna Kea in 11/08. Flagstaff in 9/09; and Mauna Kea in 1/10) that have begun the process of integrating ISRU into robotic and human exploration systems and missions, and propose future ISRU-related analog field test activities that can be performed in collaboration with international space agencies.

Differentiated Contracts: Giving Students Freedom to Learn

ERIC Educational Resources Information Center

Duncan, Tisha Admire

2013-01-01

Using Tomlinson's (2004) framework, the post-secondary classroom can be transformed into a community of learners where different avenues are provided for effectively acquiring content, processing ideas, and developing products. This article explores how instructors can differentiate instruction in teacher-education methods courses by…

50 CFR 296.4 - Claims eligible for compensation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... compensation. (a) Claimants. Damage or loss eligible for Fund compensation must be suffered by a commercial... caused by materials, equipment, tools, containers, or other items associated with OCS oil and gas... gas exploration, development, or production activities in OCS waters. (c) Exceptions. Damage or loss...

A Look at Children in China.

ERIC Educational Resources Information Center

Cohen, Dorothy H.; And Others

This paper explores educational philosophy and its effect on children's development in the People's Republic of China. The Chinese educational system incorporates heterogeneous classrooms and opportunities to "serve the people" through meaningful, productive work in order to foster a perception of group membership among students. The…

30 CFR 250.300 - Pollution prevention.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Pollution prevention. 250.300 Section 250.300... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution Prevention and Control § 250.300 Pollution prevention. (a) During the exploration, development, production, and...

Terminology Manual.

ERIC Educational Resources Information Center

Felber, Helmut

A product of the International Information Center for Terminology (Infoterm), this manual is designed to serve as a reference tool for practitioners active in terminology work and documentation. The manual explores the basic ideas of the Vienna School of Terminology and explains developments in the area of applied computer aided terminography…

A Tropical Marine Microbial Natural Products Geobibliography as an Example of Desktop Exploration of Current Research Using Web Visualisation Tools

PubMed Central

Mukherjee, Joydeep; Llewellyn, Lyndon E; Evans-Illidge, Elizabeth A

2008-01-01

Microbial marine biodiscovery is a recent scientific endeavour developing at a time when information and other technologies are also undergoing great technical strides. Global visualisation of datasets is now becoming available to the world through powerful and readily available software such as Worldwind™, ArcGIS Explorer™ and Google Earth™. Overlaying custom information upon these tools is within the hands of every scientist and more and more scientific organisations are making data available that can also be integrated into these global visualisation tools. The integrated global view that these tools enable provides a powerful desktop exploration tool. Here we demonstrate the value of this approach to marine microbial biodiscovery by developing a geobibliography that incorporates citations on tropical and near-tropical marine microbial natural products research with Google Earth™ and additional ancillary global data sets. The tools and software used are all readily available and the reader is able to use and install the material described in this article. PMID:19172194

Medical Grade Water Generation for Intravenous Fluid Production on Exploration Missions

NASA Technical Reports Server (NTRS)

Niederhaus, Charles E.; Barlow, Karen L.; Griffin, DeVon W.; Miller, Fletcher J.

2008-01-01

This document describes the intravenous (IV) fluids requirements for medical care during NASA s future Exploration class missions. It further discusses potential methods for generating such fluids and the challenges associated with different fluid generation technologies. The current Exploration baseline mission profiles are introduced, potential medical conditions described and evaluated for fluidic needs, and operational issues assessed. Conclusions on the fluid volume requirements are presented, and the feasibility of various fluid generation options are discussed. A separate report will document a more complete trade study on the options to provide the required fluids.At the time this document was developed, NASA had not yet determined requirements for medical care during Exploration missions. As a result, this study was based on the current requirements for care onboard the International Space Station (ISS). While we expect that medical requirements will be different for Exploration missions, this document will provide a useful baseline for not only developing hardware to generate medical water for injection (WFI), but as a foundation for meeting future requirements. As a final note, we expect WFI requirements for Exploration will be higher than for ISS care, and system capacity may well need to be higher than currently specified.

Oil and gas taxation in Algeria: exploration and production activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frilet, M.

1982-09-01

The Algerian taxation scheme for foreign companies involved in the petroleum sector is profoundly different depending on whether the company is directly involved in exploration and production or is merely acting as a service company or contractor. This article discusses Algerian taxation of foreign companies directly involved in production and exploration.

Sources for Leads: Natural Products and Libraries.

PubMed

van Herwerden, Eric F; Süssmuth, Roderich D

2016-01-01

Natural products have traditionally been a major source of leads in the drug discovery process. However, the development of high-throughput screening led to an increased interest in synthetic methods that enabled the rapid construction of large libraries of molecules. This resulted in the termination or downscaling of many natural product research programs, but the chemical libraries did not necessarily produce a larger amount of drug leads. On one hand, this chapter explores the current state of natural product research within the drug discovery process. On the other hand it evaluates the efforts made to increase the amount of leads generated from chemical libraries and considers what role natural products could play here.

Product Lifecycle Management and the Quest for Sustainable Space Exploration Solutions

NASA Technical Reports Server (NTRS)

Caruso, Pamela W.; Dumbacher, Daniel L.; Grieves, Michael

2011-01-01

Product Lifecycle Management (PLM) is an outcome of lean thinking to eliminate waste and increase productivity. PLM is inextricably tied to the systems engineering business philosophy, coupled with a methodology by which personnel, processes and practices, and information technology combine to form an architecture platform for product design, development, manufacturing, operations, and decommissioning. In this model, which is being implemented by the Marshall Space Flight Center (MSFC) Engineering Directorate, total lifecycle costs are important variables for critical decision-making. With the ultimate goal to deliver quality products that meet or exceed requirements on time and within budget, PLM is a powerful concept to shape everything from engineering trade studies and testing goals, to integrated vehicle operations and retirement scenarios. This briefing will demonstrate how the MSFC Engineering Directorate is implementing PLM as part of an overall strategy to deliver safe, reliable, and affordable space exploration solutions and how that strategy aligns with the Agency and Center systems engineering policies and processes. Sustainable space exploration solutions demand that all lifecycle phases be optimized, and engineering the next generation space transportation system requires a paradigm shift such that digital tools and knowledge management, which are central elements of PLM, are used consistently to maximum effect. Adopting PLM, which has been used by the aerospace and automotive industry for many years, for spacecraft applications provides a foundation for strong, disciplined systems engineering and accountable return on investment. PLM enables better solutions using fewer resources by making lifecycle considerations in an integrative decision-making process.

Developing Terrestrial Trophic Models for Petroleum and Natural Gas Exploration and Production Sites: The Oklahoma Tallgrass Prairie Preserve Example

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevenson, M; Coty, J; Stewart, J

This document details procedures to be used when constructing a conceptual terrestrial trophic model for natural gas and oil exploration and production sites. A site conceptual trophic model is intended for use in evaluating ecological impacts of oil and brine releases at E&P sites from a landscape or ecosystem perspective. The terrestrial trophic model protocol was developed using an example site, the Tallgrass Prairie Preserve (TPP) in Oklahoma. The procedure focuses on developing a terrestrial trophic model using information found in the primary literature, and augmented using site-specific research where available. Although the TPP has been the subject of considerablemore » research and public interest since the high-profile reintroduction of bison (Bison bison) in 1993, little formal work has been done to develop a food web for the plant and animal communities found at the preserve. We describe how to divide species into guilds using explicit criteria on the basis of resource use and spatial distribution. For the TPP, sixteen guilds were developed for use in the trophic model, and the relationships among these guilds were analyzed. A brief discussion of the results of this model is provided, along with considerations for its use and areas for further study.« less

Advantages and limitations of online communities of patients for research on health products.

PubMed

Ravoire, Sophie; Lang, Marie; Perrin, Elena

2017-02-01

The way patients and their caregivers share information on various online platforms about health topics and their own experiential knowledge presents new potential environments for research, particularly as concerns health products. The information provided individually and voluntarily by patients who are members of these online communities is a new resource for identifying and understanding precisely how health products are used, assessing their effectiveness, quantifying potential adverse effects in real-life situations, detecting subtle signs that are significant for experts in pharmacovigilance and addiction studies, and developing new assessment tools to help form new working hypotheses. How patients freely express their experiences and feelings and the reality of what they share also opens the way for societal research into health products, a field that is still under-explored. Well-established regulations govern research into health products, which uses resources and methodologies that have changed little over the years. However, the development of online communities of patients presents new possibilities in this field. The challenge we face today is defining their place among traditional research techniques. This place cannot be accepted by all stakeholders unless we first establish a firm understanding of the advantages, limitations, and constraints of these communities. The round table on this topic endeavoured to: explore these issues and develop a better understanding of the phenomenon and the different varieties of online communities and networks for patients; identify possible advantages, special features, and methodological, regulatory, and ethical limitations that researchers currently face; and finally, to put forward the first recommendations in this growing field of research. Copyright © 2017 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases

PubMed Central

Gul, Waseem; Hamann, Mark T.

2016-01-01

The marine environment produces natural products from a variety of structural classes exhibiting activity against numerous disease targets. Historically marine natural products have largely been explored as anticancer agents. The indole alkaloids are a class of marine natural products that show unique promise in the development of new drug leads. This report reviews the literature on indole alkaloids of marine origin and also highlights our own research. Specific biological activities of indole alkaloids presented here include: cytotoxicity, antiviral, antiparasitic, anti-inflammatory, serotonin antagonism, Ca-releasing, calmodulin antagonism, and other pharmacological activities. PMID:16236327

Quality and utilization of food co-products and residues

NASA Astrophysics Data System (ADS)

Cooke, P.; Bao, G.; Broderick, C.; Fishman, M.; Liu, L.; Onwulata, C.

2010-06-01

Some agricultural industries generate large amounts of low value co-products/residues, including citrus peel, sugar beet pulp and whey protein from the production of orange juice, sugar and cheese commodities, respectively. National Program #306 of the USDA Agricultural Research Service aims to characterize and enhance quality and develop new processes and uses for value-added foods and bio-based products. In parallel projects, we applied scanning microscopies to examine the molecular organization of citrus pectin gels, covalent crosslinking to reduce debonding in sugar beet pulp-PLA composites and functional modification of whey protein through extrusion in order to evaluate new methods of processing and formulating new products. Also, qualitative attributes of fresh produce that could potentially guide germ line development and crop management were explored through fluorescence imaging: synthesis and accumulation of oleoresin in habanero peppers suggest a complicated mechanism of secretion that differs from the classical scheme. Integrated imaging appears to offer significant structural insights to help understand practical properties and features of important food co-products/residues.

Modeling Manpower and Equipment Productivity in Tall Building Construction Projects

NASA Astrophysics Data System (ADS)

Mudumbai Krishnaswamy, Parthasarathy; Rajiah, Murugasan; Vasan, Ramya

2017-12-01

Tall building construction projects involve two critical resources of manpower and equipment. Their usage, however, widely varies due to several factors affecting their productivity. Currently, no systematic study for estimating and increasing their productivity is available. What is prevalent is the use of empirical data, experience of similar projects and assumptions. As tall building projects are here to stay and increase, to meet the emerging demands in ever shrinking urban spaces, it is imperative to explore ways and means of scientific productivity models for basic construction activities: concrete, reinforcement, formwork, block work and plastering for the input of specific resources in a mixed environment of manpower and equipment usage. Data pertaining to 72 tall building projects in India were collected and analyzed. Then, suitable productivity estimation models were developed using multiple linear regression analysis and validated using independent field data. It is hoped that the models developed in the study will be useful for quantity surveyors, cost engineers and project managers to estimate productivity of resources in tall building projects.

A Method for the Selection of Exploration Areas for Unconformity Uranium Deposits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, DeVerle P.; Zaluski, Gerard; Marlatt, James

2009-06-15

The method we propose employs two analyses: (1) exploration simulation and risk valuation and (2) portfolio optimization. The first analysis, implemented by the investment worth system (IWS), uses Monte Carlo simulation to integrate a wide spectrum of uncertain and varied components to a relative frequency histogram for net present value of the exploration investment, which is converted to a risk-adjusted value (RAV). Iterative rerunning of the IWS enables the mapping of the relationship of RAV to magnitude of exploration expenditure, X. The second major analysis uses RAV vs. X maps to identify that subset (portfolio) of areas that maximizes themore » RAV of the firm's multiyear exploration budget. The IWS, which is demonstrated numerically, consists of six components based on the geologic description of a hypothetical basin and project area (PA) and a mix of hypothetical and actual conditions of an unidentified area. The geology is quantified and processed by Bayesian belief networks to produce the geology-based inputs required by the IWS. An exploration investment of $60 M produced a highly skewed distribution of net present value (NPV), having mean and median values of $4,160 M and $139 M, respectively. For hypothetical mining firm Minex, the RAV of the exploration investment of $60 M is only $110.7 M. An RAV that is less than 3% of mean NPV reflects the aversion by Minex to risk as well as the magnitude of risk implicit to the highly skewed NPV distribution and the probability of 0.45 for capital loss. Potential benefits of initiating exploration of a portfolio of areas, as contrasted with one area, include increased marginal productivity of exploration as well as reduced probability for nondiscovery. For an exogenously determined multiyear exploration budget, a conceptual framework for portfolio optimization is developed based on marginal RAV exploration products for candidate PAs. PORTFOLIO, a software developed to implement optimization, allocates exploration to PAs so that the RAV of the exploration budget is maximized. Moreover, PORTFOLIO provides a means to examine the impact of magnitude of budget on the composition of the exploration portfolio and the optimum allocation of exploration to PAs that comprise the portfolio. Using fictitious data for five PAs, a numerical demonstration is provided of the use of PORTFOLIO to identify those PAs that comprise the optimum exploration portfolio and to optimally allocate the multiyear budget across portfolio PAs.« less

Using conjoint analysis to measure the acceptability of rectal microbicides among men who have sex with men in four South American cities.

PubMed

Kinsler, Janni J; Cunningham, William E; Nureña, César R; Nadjat-Haiem, Carsten; Grinsztejn, Beatriz; Casapia, Martin; Montoya-Herrera, Orlando; Sánchez, Jorge; Galea, Jerome T

2012-08-01

Conjoint Analysis (CJA), a statistical market-based technique that assesses the value consumers place on product characteristics, may be used to predict acceptability of hypothetical products. Rectal Microbicides (RM)-substances that would prevent HIV infection during receptive anal intercourse-will require acceptability data from potential users in multiple settings to inform the development process by providing valuable information on desirable product characteristics and issues surrounding potential barriers to product use. This study applied CJA to explore the acceptability of eight different hypothetical RM among 128 MSM in Lima and Iquitos, Peru; Guayaquil, Ecuador; and Rio de Janeiro, Brazil. Overall RM acceptability was highest in Guayaquil and lowest in Rio. Product effectiveness had the greatest impact on acceptability in all four cities, but the impact of other product characteristics varied by city. This study demonstrates that MSM from the same region but from different cities place different values on RM characteristics that could impact uptake of an actual RM. Understanding specific consumer preferences is crucial during RM product development, clinical trials and eventual product dissemination.

Supporting EarthScope Cyber-Infrastructure with a Modern GPS Science Data System

NASA Astrophysics Data System (ADS)

Webb, F. H.; Bock, Y.; Kedar, S.; Jamason, P.; Fang, P.; Dong, D.; Owen, S. E.; Prawirodirjo, L.; Squibb, M.

2008-12-01

Building on NASA's investment in the measurement of crustal deformation from continuous GPS, we are developing and implementing a Science Data System (SDS) that will provide mature, long-term Earth Science Data Records (ESDR's). This effort supports NASA's Earth Surface and Interiors (ESI) focus area and provide NASA's component to the EarthScope PBO. This multi-year development is sponsored by NASA's Making Earth System data records for Use in Research Environments (MEaSUREs) program. The SDS integrates the generation of ESDRs with data analysis and exploration, product generation, and modeling tools based on daily GPS data that include GPS networks in western North America and a component of NASA's Global GPS Network (GGN) for terrestrial reference frame definition. The system is expandable to multiple regional and global networks. The SDS builds upon mature data production, exploration, and analysis algorithms developed under NASA's REASoN, ACCESS, and SENH programs. This SDS provides access to positions, time series, velocity fields, and strain measurements derived from continuous GPS data obtained at tracking stations in both the Plate Boundary Observatory and other regional Western North America GPS networks, dating back to 1995. The SDS leverages the IT and Web Services developments carried out under the SCIGN/REASoN and ACCESS projects, which have streamlined access to data products for researchers and modelers, and which have created a prototype an on-the-fly interactive research environment through a modern data portal, GPS Explorer. This IT system has been designed using modern IT tools and principles in order to be extensible to any geographic location, scale, natural hazard, and combination of geophysical sensor and related data. We have built upon open GIS standards, particularly those of the OGC, and have used the principles of Web Service-based Service Oriented Architectures to provide scalability and extensibility to new services and capabilities.

An evaluation of the science needs to inform decisions on Outer Continental Shelf energy development in the Chukchi and Beaufort Seas, Alaska

USGS Publications Warehouse

Holland-Bartels, Leslie; Pierce, Brenda

2011-01-01

On March 31, 2010, Secretary of the Interior Ken Salazar announced a national strategy for Outer Continental Shelf (OCS) oil and gas development. In that announcement, the Administration outlined a three-pronged approach (U.S. Department of the Interior, 2010a): Development: "...expand development and production throughout the Gulf of Mexico, including resource-rich areas of the Eastern Gulf of Mexico..." Exploration: "...expand oil and gas exploration in frontier areas, such as the Arctic Ocean and areas in the Atlantic Ocean, to gather the information necessary to develop resources in the right places and the right ways." Conservation: "...calls for the protection of special areas like Bristol Bay in Alaska...national treasure[s] that we must protect for future generations." In a companion announcement (U.S. Department of the Interior, 2010b), within the Administration's "Exploration" component, the Secretary asked the U.S. Geological Survey (USGS) to conduct an initial, independent evaluation of the science needs that would inform the Administration's consideration of the right places and the right ways in which to develop oil and gas resources in the Arctic OCS, particularly focused on the Beaufort and Chukchi Seas (fig. 1).

The Effect of Task Planning on L2 Performance and L2 Development in Text-Based Synchronous Computer-Mediated Communication

ERIC Educational Resources Information Center

Hsu, Hsiu-Chen

2017-01-01

This study explored the effect of two planning conditions [the simultaneous use of rehearsal and careful online planning (ROP), and the careful online planning alone (OP)] on L2 production complexity and accuracy and the subsequent development of these two linguistic areas in the context of text-based synchronous computer-mediated communication.…

"I Can Use Things, but I Can't Make Anything": A Qualitative Exploration of Team Networks in the Development and Implementation of a New Undergraduate e-Compendium

ERIC Educational Resources Information Center

Latif, A.; Windle, R.; Wharrad, H.

2016-01-01

In higher education, undergraduate teaching materials are increasingly becoming available online. There is a need to understand the complex processes that happen during their production and how social networks between different groups impact on their development. This paper draws on qualitative interviews and participant drawings of their social…

Cyanobacterial Biofuels: Strategies and Developments on Network and Modeling.

PubMed

Klanchui, Amornpan; Raethong, Nachon; Prommeenate, Peerada; Vongsangnak, Wanwipa; Meechai, Asawin

Cyanobacteria, the phototrophic microorganisms, have attracted much attention recently as a promising source for environmentally sustainable biofuels production. However, barriers for commercial markets of cyanobacteria-based biofuels concern the economic feasibility. Miscellaneous strategies for improving the production performance of cyanobacteria have thus been developed. Among these, the simple ad hoc strategies resulting in failure to optimize fully cell growth coupled with desired product yield are explored. With the advancement of genomics and systems biology, a new paradigm toward systems metabolic engineering has been recognized. In particular, a genome-scale metabolic network reconstruction and modeling is a crucial systems-based tool for whole-cell-wide investigation and prediction. In this review, the cyanobacterial genome-scale metabolic models, which offer a system-level understanding of cyanobacterial metabolism, are described. The main process of metabolic network reconstruction and modeling of cyanobacteria are summarized. Strategies and developments on genome-scale network and modeling through the systems metabolic engineering approach are advanced and employed for efficient cyanobacterial-based biofuels production.

78 FR 41768 - Chemical Substances and Mixtures Used in Oil and Gas Exploration or Production; TSCA Section 21...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-11

... Substances and Mixtures Used in Oil and Gas Exploration or Production; TSCA Section 21 Petition; Reasons for... processors of oil and gas exploration and production (E&P) chemical substances and mixtures to maintain... interest to you if you manufacture (including import), process, or distribute chemical substances or...

Good Enough to Eat

ERIC Educational Resources Information Center

Swinbank, Elizabeth

2004-01-01

This article shows how the physical testing of food ingredients and products can be used as a starting point for exploring aspects of physics. The three main areas addressed are: mechanical properties of solid materials; liquid flow; optical techniques for measuring sugar concentration. The activities described were originally developed for…

Becoming Syntactic

ERIC Educational Resources Information Center

Chang, Franklin; Dell, Gary S.; Bock, Kathryn

2006-01-01

Psycholinguistic research has shown that the influence of abstract syntactic knowledge on performance is shaped by particular sentences that have been experienced. To explore this idea, the authors applied a connectionist model of sentence production to the development and use of abstract syntax. The model makes use of (a) error-based learning to…

Sectoral Patterns of Interactive Learning: An Empirical Exploration of a Case in a Dutch Region.

ERIC Educational Resources Information Center

Meeus, Marius T. H.; Oerlemans, Leon A. G.; Hage, Jerald

2001-01-01

Pursues the development of a theoretical framework that explains interactive learning between innovator firms and external actors in both the knowledge infrastructure and the production chain. Analyzes models in four sectors with distinct technological dynamics as distinguished by Pavitt. (DDR)

30 CFR 282.21 - Plans, general.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Plans, general. 282.21 Section 282.21 Mineral... § 282.21 Plans, general. (a) No exploration, testing, development, or production activities, except preliminary activities, shall be commenced or conducted on any lease except in accordance with a plan...

Constructing Virtual Worlds: Tracing the Historical Development of Learner Practices.

ERIC Educational Resources Information Center

Barab, Sasha A.; Hay, Kenneth E.; Barnett, Michael; Squire, Kurt

2001-01-01

Explored learning and instruction within a technology-rich, collaborative, participatory learning environment by tracking the emergence of shared understanding and products through student and teacher practices. Found that becoming knowledgeably skillful with respect to a particular practice or concept is a multigenerational process, evolving in…

Penal Innovation in New Zealand: He Ara Hou.

ERIC Educational Resources Information Center

Newbold, Greg; Eskridge, Chris

1994-01-01

Explores prison history/development in New Zealand, focusing on recent implementation of progressive prison operation/management program, He Ara Hou. Notes extremely positive results of program, such as higher administrative efficiency; greatly decreased levels of internal disorder; competent, stable workforce; and human product whose senses of…

Space Biosciences, Space-X, and the International Space Station

NASA Technical Reports Server (NTRS)

Wigley, Cecilia

2014-01-01

Space Biosciences Research on the International Space Station uses living organisms to study a variety of research questions. To enhance our understanding of fundamental biological processes. To develop the fundations for a safe, productive human exploration of space. To improve the quality of life on earth.

Middle East: Output expansions boost drilling

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-08-01

Iraqi exports may return to the market in limited fashion, but none of the region`s producers seems particularly concerned. They believe that global oil demand is rising fast enough to justify their additions to productive capacity. The paper discusses exploration, drilling and development, and production in Saudi Arabia, Kuwait, the Neutral Zone, Abu Dhabi, Dubai, Oman, Iran, Iraq, Yemen, Qatar, Syria, Turkey, and Sharjah. The paper also briefly mentions activities in Bahrain, Israel, Jordan, and Ras al Khaimah.

Exploration and Production of Hydrocarbon Resources in Coastal Alabama and Mississippi. Executive Summary.

DTIC Science & Technology

1984-11-01

r .-. u S FINAL GENERIC ENVIROMENTAL IMPACT SlAiLMENT .XPLORAYION AND PRODUCTION OF HYDROCARBON RESOU CES IN COASTAL AIABAMA AND MISSISSIPPI The...a service could potentially affect cultural resources in the area of development. Prior to issuing any project permit, conflicts on potential impacts...34 Air Emission. 6-34 Noise 6-34 Solid and Hazardous Waste 6-34 Socioe -conomic Characteristics 6-34 Navigation 6-34 xxiv TABLE OF CONTENTS (Continued

Analysis of spacecraft data

NASA Technical Reports Server (NTRS)

1984-01-01

A software program for the production and analysis of data from the Dynamics Explorer-A (DE-A) satellite was maintained and modified and new software initiated. A capability was developed to process DE-A plasma-wave instrument mission analysis files on the Tektronic 4027 color CRT, for which two programs were written. The algorithm for the calibration lookup table for the plasma-wave instrument data was modified and verified, and a production program to generate color FR-80 spectrograms was written.

Personal use of hair dyes and the risk of bladder cancer: results of a meta-analysis.

PubMed Central

Huncharek, Michael; Kupelnick, Bruce

2005-01-01

OBJECTIVE: This study examined the methodology of observational studies that explored an association between personal use of hair dye products and the risk of bladder cancer. METHODS: Data were pooled from epidemiological studies using a general variance-based meta-analytic method that employed confidence intervals. The outcome of interest was a summary relative risk (RRs) reflecting the risk of bladder cancer development associated with use of hair dye products vs. non-use. Sensitivity analyses were performed to explain any observed statistical heterogeneity and to explore the influence of specific study characteristics of the summary estimate of effect. RESULTS: Initially combining homogenous data from six case-control and one cohort study yielded a non-significant RR of 1.01 (0.92, 1.11), suggesting no association between hair dye use and bladder cancer development. Sensitivity analyses examining the influence of hair dye type, color, and study design on this suspected association showed that uncontrolled confounding and design limitations contributed to a spurious non-significant summary RR. The sensitivity analyses yielded statistically significant RRs ranging from 1.22 (1.11, 1.51) to 1.50 (1.30, 1.98), indicating that personal use of hair dye products increases bladder cancer risk by 22% to 50% vs. non-use. CONCLUSION: The available epidemiological data suggest an association between personal use of hair dye products and increased risk of bladder cancer. PMID:15736329

HPLC-based kinetics assay facilitates analysis of systems with multiple reaction products and thermal enzyme denaturation.

PubMed

Klingaman, Chase A; Wagner, Matthew J; Brown, Justin R; Klecker, John B; Pauley, Ethan H; Noldner, Colin J; Mays, Jared R

2017-01-01

Glucosinolates are plant secondary metabolites abundant in Brassica vegetables that are substrates for the enzyme myrosinase, a thioglucoside hydrolase. Enzyme-mediated hydrolysis of glucosinolates forms several organic products, including isothiocyanates (ITCs) that have been explored for their beneficial effects in humans. Myrosinase has been shown to be tolerant of non-natural glucosinolates, such as 2,2-diphenylethyl glucosinolate, and can facilitate their conversion to non-natural ITCs, some of which are leads for drug development. An HPLC-based method capable of analyzing this transformation for non-natural systems has been described. This current study describes (1) the Michaelis-Menten characterization of 2,2-diphenyethyl glucosinolate and (2) a parallel evaluation of this analogue and the natural analogue glucotropaeolin to evaluate effects of pH and temperature on rates of hydrolysis and product(s) formed. Methods described in this study provide the ability to simultaneously and independently analyze the kinetics of multiple reaction components. An unintended outcome of this work was the development of a modified Lambert W(x) which includes a parameter to account for the thermal denaturation of enzyme. The results of this study demonstrate that the action of Sinapis alba myrosinase on natural and non-natural glucosinolates is consistent under the explored range of experimental conditions and in relation to previous accounts. Copyright © 2016 Elsevier Inc. All rights reserved.

Nanogels for Pharmaceutical and Biomedical Applications and Their Fabrication Using 3D Printing Technologies

PubMed Central

Cho, Hyunah; Jammalamadaka, Udayabhanu

2018-01-01

Nanogels are hydrogels formed by connecting nanoscopic micelles dispersed in an aqueous medium, which give an opportunity for incorporating hydrophilic payloads to the exterior of the micellar networks and hydrophobic payloads in the core of the micelles. Biomedical and pharmaceutical applications of nanogels have been explored for tissue regeneration, wound healing, surgical device, implantation, and peroral, rectal, vaginal, ocular, and transdermal drug delivery. Although it is still in the early stages of development, due to the increasing demands of precise nanogel production to be utilized for personalized medicine, biomedical applications, and specialized drug delivery, 3D printing has been explored in the past few years and is believed to be one of the most precise, efficient, inexpensive, customizable, and convenient manufacturing techniques for nanogel production. PMID:29462901

In-situ Resources In Space

NASA Technical Reports Server (NTRS)

Curreri, Peter A.

2005-01-01

This tutorial is a primer on the motivational and materials science basis for utilizing space resources to lower the cost and increase the safety and reliability of human systems beyond Earth's orbit. Past research in materials processing in orbit will be briefly reviewed to emphasize the challenges and advantages inherent in processing materials in space. Data on resource availability from human Lunar and robotic/sensor missions beyond the Moon will be overviewed for resource relevance to human exploration and development of space. Specific scenarios such as propellant production on the Moon and Mars, and lunar photovoltaic power production from in-situ materials will be discussed in relation to exploration and commercialization of space. A conclusion will cover some of the visionary proposals for the use of space resources to extend human society and prosperity beyond Earth.

Processing of Mars Exploration Rover Imagery for Science and Operations Planning

NASA Technical Reports Server (NTRS)

Alexander, Douglass A.; Deen, Robert G.; Andres, Paul M.; Zamani, Payam; Mortensen, Helen B.; Chen, Amy C.; Cayanan, Michael K.; Hall, Jeffrey R.; Klochko, Vadim S.; Pariser, Oleg;

Preliminary Gulf Coast Coalbed Methane Exploration Maps: Depth to Wilcox, Apparent Wilcox Thickness and Vitrinite Reflectance

USGS Publications Warehouse

Barker, Charles E.; Biewick, Laura R.; Warwick, Peter D.; SanFilipo, John R.

2000-01-01

Strong economic controls on the viability of coalbed methane (CBM) prospects make coal geometry and coal property maps key elements in identifying sweet spots and production fairways. Therefore, this study seeks to identify the apparent prospective areas for CBM exploration in the Wilcox Group (Paleocene-Eocene) lignite and coalbeds by mapping net coal thickness, depth to coal, and coal rank (vitrinite reflectance). Economic factors are not considered in this CBM prospects study. Given the comparatively extensive gas pipeline and other production infrastructure development in the Gulf Coast Region, these factors seem less a control compared to other areas. However, open leasable public lands are minimal or nonexistent in the Gulf Coast region and access to the CBM prospects could be a problem.

Object technology: A white paper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jordan, S.R.; Arrowood, L.F.; Cain, W.D.

1992-05-11

Object-Oriented Technology (OOT), although not a new paradigm, has recently been prominently featured in the trade press and even general business publications. Indeed, the promises of object technology are alluring: the ability to handle complex design and engineering information through the full manufacturing production life cycle or to manipulate multimedia information, and the ability to improve programmer productivity in creating and maintaining high quality software. Groups at a number of the DOE facilities have been exploring the use of object technology for engineering, business, and other applications. In this white paper, the technology is explored thoroughly and compared with previousmore » means of developing software and storing databases of information. Several specific projects within the DOE Complex are described, and the state of the commercial marketplace is indicated.« less

Multilateral Research Opportunities in Ground Analogs

NASA Technical Reports Server (NTRS)

Corbin, Barbara J.

2015-01-01

The global economy forces many nations to consider their national investments and make difficult decisions regarding their investment in future exploration. International collaboration provides an opportunity to leverage other nations' investments to meet common goals. The Humans In Space Community shares a common goal to enable safe, reliable, and productive human space exploration within and beyond Low Earth Orbit. Meeting this goal requires efficient use of limited resources and International capabilities. The International Space Station (ISS) is our primary platform to conduct microgravity research targeted at reducing human health and performance risks for exploration missions. Access to ISS resources, however, is becoming more and more constrained and will only be available through 2020 or 2024. NASA's Human Research Program (HRP) is actively pursuing methods to effectively utilize the ISS and appropriate ground analogs to understand and mitigate human health and performance risks prior to embarking on human exploration of deep space destinations. HRP developed a plan to use ground analogs of increasing fidelity to address questions related to exploration missions and is inviting International participation in these planned campaigns. Using established working groups and multilateral panels, the HRP is working with multiple Space Agencies to invite International participation in a series of 30- day missions that HRP will conduct in the US owned and operated Human Exploration Research Analog (HERA) during 2016. In addition, the HRP is negotiating access to Antarctic stations (both US and non-US), the German :envihab and Russian NEK facilities. These facilities provide unique capabilities to address critical research questions requiring longer duration simulation or isolation. We are negotiating release of international research opportunities to ensure a multilateral approach to future analog research campaigns, hoping to begin multilateral campaigns in the latter facilities by 2017. Collaborative use of analog facilities and shared investment in the development of spaceflight countermeasures through multilateral campaigns or missions that leverage the global scientific community will focus high quality research and provide sufficient power to accelerate the development of countermeasures and drive sound recommendations for exploration missions. This panel will provide an overview of efforts to encourage and facilitate multilateral collaboration in analog missions or campaigns and describe the facilities currently under consideration to reach the common goal of enabling safe, reliable, and productive human space exploration.

The Nature and Use of Copper Reserve and Resource Data

USGS Publications Warehouse

Cox, Dennis P.; Wright, Nancy A.; Coakley, George J.

1981-01-01

Copper reserve, resource, and production data can be combined to produce disaggregated resource estimates and trends and, when combined with demand forecasts, can be used to predict future exploration and development requirements. Reserve estimates are subject to uncertainties due mainly to incomplete exploration and rapidly changing economic conditions. United States' reserve estimates in the past have been low mainly because knowledge of the magnitude of very large porphyry-copper deposits has been incomplete. Present estimates are considerably more reliable because mining firms tend to drill out deposits fully before mining and to release their reserve estimates to the public. The sum of reserves and past production yields an estimate of the total ore, total metal contained in ore, and average grade of ore originally in each of the deposits known in the United States. For most deposits, estimates of total copper in ore are low relative to the total copper in mineralized rock, and many estimates are strongly affected by the economic behavior of mining firms. A better estimate of the real distribution of copper contained in deposits can be obtained by combining past production data with resource estimates. Copper resource data are disaggregated into categories that include resources in undeveloped deposits similar to those mined in the past, resources in mines closed because of unfavorable economic conditions, resources in deep deposits requiring high-cost mining methods, arid resources in deposits located in areas where environmental restrictions have contributed to delays in development. The largest resource is located in the five largest porphyry deposits. These deposits are now being mined but the resources are not included in the present mining plan. Resources in this last category will not contribute to supply until some future time when ores presently being mined are depleted. A high correlation exists between total copper contained in deposits and annual production from deposits. This correlation can be used to predict roughly the potential production from undeveloped deposits. Large deposits annually produce relatively less metal per ton of copper contained than do medium and small deposits. Dividing reserves by annual production gives a depletion date for each copper mine. The sum of annual production capacity of all mines not yet depleted at any year of interest gives the minimum production capacity for that year. A graph of minimum production capacity by year combined with curves representing potential capacity from undeveloped identified resources can be compared with various demand scenarios to yield a measure of copper requirements from new sources. Since 1950 reserves have been developed in the United States at a rate of about 1 million tons of copper per year. Since 1960 the number of deposits developed per 10-year period has greatly increased without a commensurate increase in tonnage of copper. This is in part due to the fact that recent exploration successes have been increasingly represented by smaller and (or) lower grade deposits containing less metal.

Geodecision system for traceability and sustainable production of beef cattle in Brazil

NASA Astrophysics Data System (ADS)

Victoria, D. D.; Andrade, R. G.; Bolfe, L.; Batistella, M.; Pires, P. P.; Vicente, L. E.; Visoli, M. C.

2011-12-01

Beef cattle production sustainability depends on incorporating innovative tools and technologies which are easy to comprehend, economically viable, and spatially explicit into the registration of precise, reliable data about production practices. This research developed from the needs and demands of food safety and food quality in extensive beef cattle production within the scope of the policies of Southern Cone and European Union's countries. Initially, the OTAG project (Operational Management and Geodecisional Prototype to Track and Trace Agricultural Production) focused on the development of a prototype traceability of cattle. The aim for the project's next phase is to enhance the electronic devices used in the identification and positioning of the animals, and the incorporation of more management and sanitary information. Besides, we intend to structure a database that enables the inclusion of greater amount of geospatial information linked to environmental aspects, such as water deficit, vegetation vigour, degradation indices of pasture areas, among others. For the extraction of knowledge, and the presentation of the results, we propose the development of a friendly interface to facilitate the exploration of the textual, tabular and geospatial information useful for the user.

Concept Study: Exploration and Production in Environmentally Sensitive Arctic Areas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shirish Patil; Rich Haut; Tom Williams

2008-12-31

The Alaska North Slope offers one of the best prospects for increasing U.S. domestic oil and gas production. However, this region faces some of the greatest environmental and logistical challenges to oil and gas production in the world. A number of studies have shown that weather patterns in this region are warming, and the number of days the tundra surface is adequately frozen for tundra travel each year has declined. Operators are not allowed to explore in undeveloped areas until the tundra is sufficiently frozen and adequate snow cover is present. Spring breakup then forces rapid evacuation of the areamore » prior to snowmelt. Using the best available methods, exploration in remote arctic areas can take up to three years to identify a commercial discovery, and then years to build the infrastructure to develop and produce. This makes new exploration costly. It also increases the costs of maintaining field infrastructure, pipeline inspections, and environmental restoration efforts. New technologies are needed, or oil and gas resources may never be developed outside limited exploration stepouts from existing infrastructure. Industry has identified certain low-impact technologies suitable for operations, and has made improvements to reduce the footprint and impact on the environment. Additional improvements are needed for exploration and economic field development and end-of-field restoration. One operator-Anadarko Petroleum Corporation-built a prototype platform for drilling wells in the Arctic that is elevated, modular, and mobile. The system was tested while drilling one of the first hydrate exploration wells in Alaska during 2003-2004. This technology was identified as a potentially enabling technology by the ongoing Joint Industry Program (JIP) Environmentally Friendly Drilling (EFD) program. The EFD is headed by Texas A&M University and the Houston Advanced Research Center (HARC), and is co-funded by the National Energy Technology Laboratory (NETL). The EFD participants believe that the platform concept could have far-reaching applications in the Arctic as a drilling and production platform, as originally intended, and as a possible staging area. The overall objective of this project was to document various potential applications, locations, and conceptual designs for the inland platform serving oil and gas operations on the Alaska North Slope. The University of Alaska Fairbanks assisted the HARC/TerraPlatforms team with the characterization of potential resource areas, geotechnical conditions associated with continuous permafrost terrain, and the potential end-user evaluation process. The team discussed the various potential applications with industry, governmental agencies, and environmental organizations. The benefits and concerns associated with industry's use of the technology were identified. In this discussion process, meetings were held with five operating companies (22 people), including asset team leaders, drilling managers, HSE managers, and production and completion managers. Three other operating companies and two service companies were contacted by phone to discuss the project. A questionnaire was distributed and responses were provided, which will be included in the report. Meetings were also held with State of Alaska Department of Natural Resources officials and U.S. Bureau of Land Management regulators. The companies met with included ConcoPhillips, Chevron, Pioneer Natural Resources, Fairweather E&P, BP America, and the Alaska Oil and Gas Association.« less

US nonfuel mineral exploration: Selected findings for 1995-2009 from the USGS

USGS Publications Warehouse

Wilburn, David R.; Bleiwas, Donald I.

2012-01-01

The U.S. Geological Survey (USGS) has been systematically monitoring global nonfuel mineral exploration activities to anticipate the location and quantity of future nonfuel minerals supply for about 100 commodities, with an emphasis on precious and base metals. Since 1995, the USGS has developed an annual list of 100 noteworthy prospects that were considered to have a high level of potential for near-term development based on such criteria as intensity of drilling, level of capital investment, and size of resource. This study reviews the status of the U.S. sites included on these lists as of July 2011 and addresses domestic prospects not included on the lists that have come into production since 1995.

Approaches to flame resistant polymeric materials

NASA Technical Reports Server (NTRS)

Liepins, R.

1975-01-01

Four research and development areas are considered for further exploration in the quest of more flame-resistant polymeric materials. It is suggested that improvements in phenolphthalein polycarbonate processability may be gained through linear free energy relationship correlations. Looped functionality in the backbone of a polymer leads to both improved thermal resistance and increased solubility. The guidelines used in the pyrolytic carbon production constitute a good starting point for the development of improved flame-resistant materials. Numerous organic reactions requiring high temperatures and the techniques of protected functionality and latent functionality constitute the third area for exploration. Finally, some well-known organic reactions are suggested for the formation of polymers that were not made before.

Abandoning pipelines working group regulatory issues

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The history of hydrocarbon development in Louisiana and off its coast is one of the interdependence of technological innovation, entrepreneurial risk-taking, resource management, judicial decisions, legislation, marketing, employee good will, infrastructure and support services, coupled with favorable geologic structures that made early exploration and development relatively easy. Mariners sailing off the coast of Louisiana and Texas in the 1600`s recorded one of the earliest known natural oil seeps. They shrugged it off as unimportant, as there was no market for the substance they witnessed. The seepage, however, provided a tiny clue to the vast storehouse of hydrocarbons trapped in themore » earth`s crust extending from the uplands, through Louisiana`s swamps and marshes, and into the subaqueous habitats of the Gulf of Mexico-the world`s ninth largest body of water. In all cases, each move into a new geographic province required considerable change in operation philosophy and in the science supporting the exploration and development activity. As technology changed, or was developed to meet the industry`s needs, new frontiers were explored. However, with time-as is the case with any nonrenewable resource-fields and wells lost their productive life. They had to be abandoned. In fact, the Minerals Management Service suggests that within the next 10 years the offshore industry will remove 150 platforms per year, or nearly half of the current number of production units. The industry will be asked to dispose of nearly one unit every 2.4 days. If this is the case, abandonment issues are going to continue to surface.« less

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development.

PubMed

Tomar, Dheeraj S; Kumar, Sandeep; Singh, Satish K; Goswami, Sumit; Li, Li

2016-01-01

Effective translation of breakthrough discoveries into innovative products in the clinic requires proactive mitigation or elimination of several drug development challenges. These challenges can vary depending upon the type of drug molecule. In the case of therapeutic antibody candidates, a commonly encountered challenge is high viscosity of the concentrated antibody solutions. Concentration-dependent viscosity behaviors of mAbs and other biologic entities may depend on pairwise and higher-order intermolecular interactions, non-native aggregation, and concentration-dependent fluctuations of various antibody regions. This article reviews our current understanding of molecular origins of viscosity behaviors of antibody solutions. We discuss general strategies and guidelines to select low viscosity candidates or optimize lead candidates for lower viscosity at early drug discovery stages. Moreover, strategies for formulation optimization and excipient design are also presented for candidates already in advanced product development stages. Potential future directions for research in this field are also explored.

Teaching, Learning, and Planetary Exploration

NASA Technical Reports Server (NTRS)

Brown, Robert A.

2002-01-01

This is the final report of a program that examined the fundamentals of education associated with space activities, promoted educational policy development in appropriate forums, and developed pathfinder products and services to demonstrate the utility of advanced communication technologies for space-based education. Our focus was on space astrophysics and planetary exploration, with a special emphasis on the themes of the Origins Program, with which the Principal Investigator (PI) had been involved from the outset. Teaching, Learning, and Planetary Exploration was also the core funding of the Space Telescope Science Institute's (ST ScI) Special Studies Office (SSO), and as such had provided basic support for such important NASA studies as the fix for Hubble Space Telescope (HST) spherical aberration, scientific conception of the HST Advanced Camera, specification of the Next-Generation Space Telescope (NGST), and the strategic plan for the second decade of the HST science program.

Overview of the Human Exploration Research Analog (HERA)

NASA Technical Reports Server (NTRS)

Neigut, J.

2015-01-01

In 2013, the Human Research Program at NASA began developing a new confinement analog specifically for conducting research to investigate the effects of confinement on the human system. The HERA (Human Exploration Research Analog) habitat has been used for both 7 and 14 day missions to date to examine and mitigate exploration risks to enable safe, reliable and productive human space exploration. This presentation will describe how the Flight Analogs Project developed the HERA facility and the infrastructure to suit investigator requirements for confinement research and in the process developed a new approach to analog utilization and a new state of the art analog facility. Details regarding HERA operations will be discussed including specifics on the mission simulation utilized for the current 14-day campaign, the specifics of the facility (total volume, overall size, hardware), and the capabilities available to researchers. The overall operational philosophy, mission fidelity including timeline, schedule pressures and cadence, and development and implementation of mission stressors will be presented. Research conducted to date in the HERA has addressed risks associated with behavioral health and performance, human physiology, as well as human factors. This presentation will conclude with a discussion of future research plans for the HERA, including infrastructure improvements and additional research capabilities planned for the upcoming 30-day missions in 2016.

Petroleum developments in Middle East countries in 1967

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mason, J.F.; Moore, Q.M.

1968-08-01

Petroleum production in Middle East countries in 1967 totaled 3,679,506,000 bbl at an average rate of 10,080,838 bpd. This compares with 3,407,666,000 bbl or 9,336,071 bpd in 1966. The principal production increases were in Iran, Kuwait, Saudi Arabia, Qatar offshore, Abu Dhabi, and Oman (first production). New fields were found in offshore Iran, Neutral Zone, and Saudi Arabia. There were no exploration activities in Iraq, Aden, Kamaran Islands, Yeman, Hadramaut, and Cyprus. The main areas of exploratory work were in Iran, Saudi Arabia, Neutral Zone, and the southern Gulf (both onshore and offshore).

The Impact of a Potential Shale Gas Development in Germany and the United Kingdom on Pollutant and Greenhouse Gas Emissions

NASA Astrophysics Data System (ADS)

Weger, L.; Cremonese, L.; Bartels, M. P.; Butler, T. M.

2016-12-01

Several European countries with domestic shale gas reserves are considering extracting this natural gas resource to complement their energy transition agenda. Natural gas, which produces lower CO2 emissions upon combustion compared to coal or oil, has the potential to serve as a bridge in the transition from fossil fuels to renewables. However, the generation of shale gas leads to emissions of CH4 and pollutants such as PM, NOx and VOCs, which in turn impact climate as well as local and regional air quality. In this study, we explore the impact of a potential shale gas development in Europe, specifically in Germany and the United Kingdom, on emissions of greenhouse gases and pollutants. In order to investigate the effect on emissions, we first estimate a range of wells drilled per year and production volume for the two countries under examination based on available geological information and on regional infrastructural and economic limitations. Subsequently we assign activity data and emissions factors to the well development, gas production and processing stages of shale gas generation to enable emissions quantification. We then define emissions scenarios to explore different storylines of potential shale gas development, including low emissions (high level of regulation), high emissions (low level of regulation) and middle emissions scenarios, which influence fleet make-up, emission factor and activity data choices for emissions quantification. The aim of this work is to highlight important variables and their ranges, to promote discussion and communication of potential impacts, and to construct possible visions for a future shale gas development in the two study countries. In a follow-up study, the impact of pollutant emissions from these scenarios on air quality will be explored using the Weather Research and Forecasting model with chemistry (WRF-Chem) model.

Miniature Earthmover

NASA Technical Reports Server (NTRS)

1996-01-01

International Machinery Corporation (IMC) developed a miniature earthmover, the 1/8 scale Caterpillar D11N Track-type Tractor, with trademark product approval and manufacturing/marketing license from Caterpillar, Inc. Through Marshall Space Flight Center assistance, the company has acquired infrared remote control technology, originally developed for space exploration. The technology is necessary for exports because of varying restrictions on radio frequency in foreign countries. The Cat D11N weighs only 340 pounds and has the world's first miniature industrial internal combustion engine. The earthmover's uses include mining, construction and demolition work, and hazardous environment work. IMC also has designs of various products for military use and other Caterpillar replicas.

Employee Performance and State Mental Health Manpower Development.

ERIC Educational Resources Information Center

McCullough, Paul M.

A project explored the manpower issue termed "burnout" and the impact of this phenomenon on mental health service programs. (In the framework of this study burnout is defined as that state of non-productivity, non-motivation, and indifference which interferes with a worker's delivering services effectively.) Existing literature does not clearly…

Effects of a Service-Learning Program on University Students

ERIC Educational Resources Information Center

Hervás Torres, Mirian; Fernández Martín, Francisco D.; Arco Tirado, José Luis; Miñaca Laprida, María Isabel

2017-01-01

Introduction: The low productivity that prevailing in recent years in Higher Education requires urgently institutional responses aimed to improving quality of university education contributing to the development among students of key competences for lifelong learning. In this sense, the aim of this research was to explore the effects of an…

The Arctic National Wildlife Refuge: An Interdisciplinary Unit.

ERIC Educational Resources Information Center

Thieman, Gayle; Geil, Mike

This paper presents a set of interdisciplinary lessons for teaching about the Arctic National Wildlife Refuge (Alaska). Lessons include a petroleum product treasure hunt, an examination of life without petroleum, the development of a wildlife poster, an exploration of the tundra ecosystem and the plants and animals that live there, identification…

The Purchasing Power of Collaboration

ERIC Educational Resources Information Center

Rosenthal, Amy; Mavrolas, Pamela; Rusmore, Barbara; Liquori, Toni

2017-01-01

Purpose/Objectives: School Food Focus (Focus) developed the Focus Midwest project on the premise that school food professionals (SFPs) could work together to minimize effort and maximize potential to find new or improved products to serve. Focus designed this project as an experiment to explore how and to what extent this collaborative approach…

A Game of Thrones: Organising and Legitimising Knowledge through PISA Research

ERIC Educational Resources Information Center

Mølstad, Christina E.; Pettersson, Daniel; Forsberg, Eva

2017-01-01

This study investigates knowledge structures and scientific communication using bibliometric methods to explore scientific knowledge production and dissemination. The aim is to develop knowledge about this growing field by investigating studies using international large-scale assessment (ILSA) data, with a specific focus on those using Programme…

Syria Country Analysis Brief

EIA Publications

2015-01-01

Syria's energy sector has encountered a number of challenges as a result of conflict and subsequent sanctions imposed by the United States and the European Union. Damage to energy infrastructure—including oil and natural gas pipelines and electricity transmission networks—hindered the exploration, development, production, and transport of the country's energy resources.

Benefit assessment of NASA space technology goals

NASA Technical Reports Server (NTRS)

1976-01-01

The socio-economic benefits to be derived from system applications of space technology goals developed by NASA were assessed. Specific studies include: electronic mail; personal telephone communications; weather and climate monitoring, prediction, and control; crop production forecasting and water availability; planetary engineering of the planet Venus; and planetary exploration.

Community Connections in Health and Physical Education: A Reflection of Stakeholder Experiences

ERIC Educational Resources Information Center

McGrath, Georgia; Alfrey, Laura; Jeanes, Ruth

2017-01-01

Community development research suggests that positive partnerships and connections between groups can result in stronger, more resilient and productive communities. Despite community connections featuring increasingly at a curriculum level in countries such as Australia and New Zealand, research is only beginning to explore the nuanced processes…

Changes in Articulator Movement Variability during Phonemic Development: A Longitudinal Study

ERIC Educational Resources Information Center

Grigos, Maria I.

2009-01-01

Purpose: The present study explored articulator movement variability during voicing contrast acquisition. The purpose was to examine whether oral articulator movement trajectories associated with the production of voiced/voiceless bilabial phonemes in children became less variable over time. Method: Jaw, lower lip, and upper lip movements were…

30 CFR 256.71 - Directional drilling.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Directional drilling. 256.71 Section 256.71..., and Extensions § 256.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a lease may be maintained in force by directional wells drilled under the...

30 CFR 556.71 - Directional drilling.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Directional drilling. 556.71 Section 556.71... SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 556.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a...

30 CFR 256.71 - Directional drilling.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Directional drilling. 256.71 Section 256.71... OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 256.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a lease may...

30 CFR 556.71 - Directional drilling.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Directional drilling. 556.71 Section 556.71... SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 556.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a...

30 CFR 556.71 - Directional drilling.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Directional drilling. 556.71 Section 556.71... SULPHUR OR OIL AND GAS IN THE OUTER CONTINENTAL SHELF Assignments, Transfers, and Extensions § 556.71 Directional drilling. In accordance with an approved exploration plan or development and production plan, a...

Differential Effects of Explicit Form-Focused Instruction on Morphosyntactic Development

ERIC Educational Resources Information Center

Xu, Hainu; Lyster, Roy

2014-01-01

This study explores whether and to what degree explicit form-focused instruction (FFI) facilitates the use of morphosyntactic forms in second language oral production and also whether it has differential effects on morphosyntactic forms with different linguistic variables. Twenty-seven university-level Chinese EFL participants were randomly…

READING MACHINES FOR THE BLIND.

ERIC Educational Resources Information Center

FREIBERGER, HOWARD; MURPHY, EUGENE F.

AT A TECHNICAL SESSION, SIXTY-ONE PARTICIPANTS FROM THE FIELDS OF EDUCATION, INDUSTRY, GOVERNMENT, AND AGENCIES OF THE BLIND DISCUSSED RECENT DEVELOPMENTS IN THE PRODUCTION AND USE OF READING MACHINES WHICH PERMIT BLIND PERSONS GREATER INDEPENDENCE IN READING THE PRINTED PAGE. THEY ALSO EXPLORED PROBLEMS INHERENT IN THESE EFFORTS AND PROPOSED…

Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner

USDA-ARS?s Scientific Manuscript database

Multiple strategies have been explored throughout the world to meet food security. These include molecular breeding, transgenic genotype development, reduced-tillage crop production, modification of the soil environment with cover crops or polyethylene mulches and tunnels, and organic farming. Unde...

Watching as Working: The Valorization of Audience Consciousness.

ERIC Educational Resources Information Center

Jhally, Sut; Livant, Bill

1986-01-01

Explores the argument that television exemplifies the production and reflection of surplus value and that watching, as an activity, reflects the organization of human labor in the economy as a whole. Develops the basis for a materialist theory of the advertising-supported media industries in advanced industrial societies. (JD)

Careers in Art. Career Development Project.

ERIC Educational Resources Information Center

Gergeceff, Lorraine; Wheeler, Geoffrey

The 10 activities in the unit on art careers attempt to provide eighth and ninth grade students with opportunities for acquiring occupational information, to help students discover themselves in relation to art careers, and to explore various clusters of careers. The suggested occupational areas are: architecture, product design, cartooning,…

'Where are the lesbians in Chaucer?' Lack, opportunity and female homoeroticism in Medieval Studies today.

PubMed

Sauer, Michelle M

2007-01-01

This article explores the study of lesbians in the Middle Ages and proposes that the unstable construct of lesbian poses a problem for traditional Medieval Studies that can lead to the development in Medieval Studies of more nuanced and productive theorizing.

Diversity Matters: Parent Input Predicts Toddler Verb Production

ERIC Educational Resources Information Center

Hsu, Ning; Hadley, Pamela A.; Rispoli, Matthew

2017-01-01

The contribution of parent input to children's subsequent expressive verb diversity was explored in twenty typically developing toddlers with small verb lexicons. Child developmental factors and parent input measures (i.e. verb quantity, verb diversity, and verb-related structural cues) at age 1;9 were examined as potential predictors of…

Impact of VOC Composition and Reactor Conditions on the Aging of Biomass Cookstove Emission in an Oxidation Flow Reactor

EPA Science Inventory

Oxidation flow reactor (OFR) experiments in our lab have explored secondary organic aerosol (SOA) production during photochemical aging of emissions from cookstoves used by billions in developing countries. Previous experiments, conducted with red oak fuel under conditions of hig...

Impact of VOC Composition and Reactor Conditions on the Aging of Biomass Cookstove Emissions in an Oxidation Flow Reactor

EPA Science Inventory

Oxidation flow reactor (OFR) experiments in our lab have explored secondary organic aerosol (SOA) production during photochemical aging of emissions from cookstoves used by billions in developing countries. Previous experiments, conducted with red oak fuel under conditions of hig...

Marketing Outputs as Art? Bringing an Aesthetic Sensibility to the Marketing Curriculum

ERIC Educational Resources Information Center

Petkus, Ed, Jr.; Budeva, Desislava; Chung, Christina; Dzhogleva, Hristina

2011-01-01

Can marketing outputs--advertising, packaging, product design, and retail environments--be considered a form of art? This paper explores the potential for incorporating the theories and concepts of aesthetics in the marketing curriculum in order to facilitate students' capacity to interpret marketing outputs and develop effective practical…

Knowing the Other/Other Ways of Knowing: Indigenous Feminism, Testimonial, and Anti-Globalization Street Discourse

ERIC Educational Resources Information Center

Dulfano, Isabel

2017-01-01

In this article, I explore the relationship between anti-globalization counter hegemonic discourse and Indigenous feminist alternative knowledge production. Although seemingly unrelated, the autoethnographic writing of some Indigenous feminists from Latin America questions the assumptions and presuppositions of Western development models and…

Whiteness and absorbency of hydroentangled cotton-based nonwoven fabrics of different constituent fibers and fiber blends

USDA-ARS?s Scientific Manuscript database

This manuscript reports result of the research efforts devoted to the exploration and development of greige (non-bleached) cotton-containing nonwoven fabrics that likely could be made optimally competitive in cost, quality and performance to existing products that presently and predominantly use man...

Reduced-tillage organic corn production in a hairy vetch cover crop

USDA-ARS?s Scientific Manuscript database

There is much interest in developing no-tillage systems for organic farming, however, potential limitations include the inability to control weeds and to provide sufficient crop available N. A three-year field experiment was conducted on organically-certified land to explore the use of roller-crimp...

Context and Expertise: The Case of Electronic Troubleshooting.

ERIC Educational Resources Information Center

Flesher, Jeffrey W.

Electronic troubleshooting expertise was explored in the three contexts (design, production, and repair) that reflect distinct problem solving task environments. The purpose of the effort was to provide a more precise definition of the boundaries of expertise in electronics troubleshooting and the relationship of context to the development of…

NASA Lunar and Planetary Mapping and Modeling

NASA Astrophysics Data System (ADS)

Day, Brian; Law, Emily

2016-10-01

NASA's Lunar and Planetary Mapping and Modeling Portals provide web-based suites of interactive visualization and analysis tools to enable mission planners, planetary scientists, students, and the general public to access mapped lunar data products from past and current missions for the Moon, Mars, and Vesta. New portals for additional planetary bodies are being planned. This presentation will recap some of the enhancements to these products during the past year and preview work currently being undertaken.New data products added to the Lunar Mapping and Modeling Portal (LMMP) include both generalized products as well as polar data products specifically targeting potential sites for the Resource Prospector mission. New tools being developed include traverse planning and surface potential analysis. Current development work on LMMP also includes facilitating mission planning and data management for lunar CubeSat missions. Looking ahead, LMMP is working with the NASA Astromaterials Office to integrate with their Lunar Apollo Sample database to help better visualize the geographic contexts of retrieved samples. All of this will be done within the framework of a new user interface which, among other improvements, will provide significantly enhanced 3D visualizations and navigation.Mars Trek, the project's Mars portal, has now been assigned by NASA's Planetary Science Division to support site selection and analysis for the Mars 2020 Rover mission as well as for the Mars Human Landing Exploration Zone Sites, and is being enhanced with data products and analysis tools specifically requested by the proposing teams for the various sites. NASA Headquarters is giving high priority to Mars Trek's use as a means to directly involve the public in these upcoming missions, letting them explore the areas the agency is focusing upon, understand what makes these sites so fascinating, follow the selection process, and get caught up in the excitement of exploring Mars.The portals also serve as outstanding resources for education and outreach. As such, they have been designated by NASA's Science Mission Directorate as key supporting infrastructure for the new education programs selected through the division's recent CAN.

Quantitative and qualitative differences in the lexical knowledge of monolingual and bilingual children on the LITMUS-CLT task.

PubMed

Altman, Carmit; Goldstein, Tamara; Armon-Lotem, Sharon

2017-01-01

While bilingual children follow the same milestones of language acquisition as monolingual children do in learning the syntactic patterns of their second language (L2), their vocabulary size in L2 often lags behind compared to monolinguals. The present study explores the comprehension and production of nouns and verbs in Hebrew, by two groups of 5- to 6-year olds with typical language development: monolingual Hebrew speakers (N = 26), and Russian-Hebrew bilinguals (N = 27). Analyses not only show quantitative gaps between comprehension and production and between nouns and verbs, with a bilingual effect in both, but also a qualitative difference between monolinguals and bilinguals in their production errors: monolinguals' errors reveal knowledge of the language rules despite temporary access difficulties, while bilinguals' errors reflect gaps in their knowledge of Hebrew (L2). The nature of Hebrew as a Semitic language allows one to explore this qualitative difference in the semantic and morphological level.

Coproduction of healthcare service.

PubMed

Batalden, Maren; Batalden, Paul; Margolis, Peter; Seid, Michael; Armstrong, Gail; Opipari-Arrigan, Lisa; Hartung, Hans

2016-07-01

Efforts to ensure effective participation of patients in healthcare are called by many names-patient centredness, patient engagement, patient experience. Improvement initiatives in this domain often resemble the efforts of manufacturers to engage consumers in designing and marketing products. Services, however, are fundamentally different than products; unlike goods, services are always 'coproduced'. Failure to recognise this unique character of a service and its implications may limit our success in partnering with patients to improve health care. We trace a partial history of the coproduction concept, present a model of healthcare service coproduction and explore its application as a design principle in three healthcare service delivery innovations. We use the principle to examine the roles, relationships and aims of this interdependent work. We explore the principle's implications and challenges for health professional development, for service delivery system design and for understanding and measuring benefit in healthcare services. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Managed Entry Agreements for Pharmaceuticals in the Context of Adaptive Pathways in Europe.

PubMed

Bouvy, Jacoline C; Sapede, Claudine; Garner, Sarah

2018-01-01

As per the EMA definition, adaptive pathways is a scientific concept for the development of medicines which seeks to facilitate patient access to promising medicines addressing high unmet need through a prospectively planned approach in a sustainable way. This review reports the findings of activities undertaken by the ADAPT-SMART consortium to identify enablers and explore the suitability of managed entry agreements for adaptive pathways products in Europe. We found that during 2006-2016 outcomes-based managed entry agreements were not commonly used for products with a conditional marketing authorization or authorized under exceptional circumstances. The barriers and enablers to develop workable managed entry agreements models for adaptive pathways products were discussed through interviews and a multi-stakeholder workshop with a number of recommendations made in this paper.

Usability in product development practice; an exploratory case study comparing four markets.

PubMed

van Kuijk, Jasper; van Driel, Liesbeth; van Eijk, Daan

2015-03-01

This study explored how usability was dealt with in four product development organizations active in different sectors: high-end automotive, professional printers and copiers, office coffee makers and fast moving consumer goods. The primary differentiators of the selected cases were whether they were targeting businesses or consumers and the degree of product complexity. Interviews with 19 product development practitioners were conducted, focussing on three topics: 1) the product development process and the integration of user involvement, 2) multidisciplinary teamwork, and 3) organizational attitude towards usability. Based on the interviews, context descriptions of the companies were created and barriers and enablers for usability were identified. To verify the findings and to discuss remaining issues a feedback workshop was held in which the primary contact from each company participated. The results indicate that differences in product-market combination lead to differences in organizational attitude towards usability. The prioritization of usability in an organization seems to be influenced by the degree of product complexity (complex products are more prone to suffer from usability issues) and whether developers think that usability is a purchase consideration for their clients. The product-market combination a company targets also affects the methods for user-centred design that a company can apply and that are relevant. What methods for user-centred design are used also seems to be influenced by the attitude towards usability: if usability is considered more important, methods that require more resources can be applied. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Commercialization of nanotechnology.

PubMed

Hobson, David W

2009-01-01

The emerging and potential commercial applications of nanotechnologies clearly have great potential to significantly advance and even potentially revolutionize various aspects of medical practice and medical product development. Nanotechnology is already touching upon many aspects of medicine, including drug delivery, diagnostic imaging, clinical diagnostics, nanomedicines, and the use of nanomaterials in medical devices. This technology is already having an impact; many products are on the market and a growing number is in the pipeline. Momentum is steadily building for the successful development of additional nanotech products to diagnose and treat disease; the most active areas of product development are drug delivery and in vivo imaging. Nanotechnology is also addressing many unmet needs in the pharmaceutical industry, including the reformulation of drugs to improve their bioavailability or toxicity profiles. The advancement of medical nanotechnology is expected to advance over at least three different generations or phases, beginning with the introduction of simple nanoparticulate and nanostructural improvements to current product and process types, then eventually moving on to nanoproducts and nanodevices that are limited only by the imagination and limits of the technology itself. This review looks at some recent developments in the commercialization of nanotechnology for various medical applications as well as general trends in the industry, and explores the nanotechnology industry that is involved in developing medical products and procedures with a view toward technology commercialization. (c) 2009 John Wiley & Sons, Inc.

Two decades of hydrocarbon exploration activity in Indonesia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suardy, A.; Taruno, J.; Simbolon, P.H.

1986-07-01

During the past two decades, hydrocarbon exploration activity within Indonesia has been based on the Indonesian Energy Policy, aims of which include intensifying and expanding hydrocarbon exploration programs. Expansion into the offshore regions of the nation has resulted in the discovery of petroliferous basins. The first offshore oil production came on stream in 1971. Since then, significant achievements have been made in developing these resources. Intensified onshore exploration has resulted in additional oil fields being discovered in these more mature areas. Among the significant gas fields discovered during the past 20 years, Arun and Badak both supply major LNG projects.more » Oil fields have been found in the onshore areas of Sumatra, Kalimantan, Java, and Irian Jaya, and in the offshore areas around West Java, Madura, Natuna, and East Kalimantan. The exploration drilling success during this time has been approximately 32%. In addition, the ratio of oil field development to these discoveries is about 54%. For technical and economic reasons, not all discoveries can be developed into oil fields. Recently, Pertamina's Research and Development Division organized the study of data contributed by Pertamina exploration, foreign contractors, and science institutes. This study reveals that 60 basins are spread throughout the onshore and offshore areas of the nation. Using PAUS (plan and analysis of uncertainty situation), a Monte Carolo simulation program, the hydrocarbon potential of each basin has been estimated. These estimates will be continually revised as more data are made available to the study, as the geology of Indonesia is better understood in terms of plate tectonic theory, and as computing techniques improve.« less

Fundamentals and applications of solar energy. Part 2

NASA Astrophysics Data System (ADS)

Faraq, I. H.; Melsheimer, S. S.

Applications of techniques of chemical engineering to the development of materials, production methods, and performance optimization and evaluation of solar energy systems are discussed. Solar thermal storage systems using phase change materials, liquid phase Diels-Alder reactions, aquifers, and hydrocarbon oil were examined. Solar electric systems were explored in terms of a chlorophyll solar cell, the nonequilibrium electric field effects developed at photoelectrode/electrolyte interfaces, and designs for commercial scale processing of solar cells using continuous thin-film coating production methods. Solar coal gasification processes were considered, along with multilayer absorber coatings for solar concentrator receivers, solar thermal industrial applications, the kinetics of anaerobic digestion of crop residues to produce methane, and a procedure for developing a computer simulation of a solar cooling system.

Human Centered Autonomous and Assistant Systems Testbed for Exploration Operations

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Mount, Frances; Carreon, Patricia; Torney, Susan E.

2001-01-01

The Engineering and Mission Operations Directorates at NASA Johnson Space Center are combining laboratories and expertise to establish the Human Centered Autonomous and Assistant Systems Testbed for Exploration Operations. This is a testbed for human centered design, development and evaluation of intelligent autonomous and assistant systems that will be needed for human exploration and development of space. This project will improve human-centered analysis, design and evaluation methods for developing intelligent software. This software will support human-machine cognitive and collaborative activities in future interplanetary work environments where distributed computer and human agents cooperate. We are developing and evaluating prototype intelligent systems for distributed multi-agent mixed-initiative operations. The primary target domain is control of life support systems in a planetary base. Technical approaches will be evaluated for use during extended manned tests in the target domain, the Bioregenerative Advanced Life Support Systems Test Complex (BIO-Plex). A spinoff target domain is the International Space Station (ISS) Mission Control Center (MCC). Prodl}cts of this project include human-centered intelligent software technology, innovative human interface designs, and human-centered software development processes, methods and products. The testbed uses adjustable autonomy software and life support systems simulation models from the Adjustable Autonomy Testbed, to represent operations on the remote planet. Ground operations prototypes and concepts will be evaluated in the Exploration Planning and Operations Center (ExPOC) and Jupiter Facility.

Natural products discovery from micro-organisms in the post-genome era.

PubMed

Ikeda, Haruo

2017-01-01

With the decision to award the Nobel Prize in Physiology or Medicine to Drs. S. Ōmura, W.C. Campbell, and Y. Tu, the importance and usefulness of natural drug discovery and development have been revalidated. Since the end of the twentieth century, many genome analyses of organisms have been conducted, and accordingly, numerous microbial genomes have been decoded. In particular, genomic studies of actinomycetes, micro-organisms that readily produce natural products, led to the discovery of biosynthetic gene clusters responsible for producing natural products. New explorations for natural products through a comprehensive approach combining genomic information with conventional methods show great promise for the discovery of new natural products and even systematic generation of unnaturally occurring compounds.

Workshop on Advanced Technologies for Planetary Instruments, part 1

NASA Technical Reports Server (NTRS)

Appleby, John F. (Editor)

1993-01-01

This meeting was conceived in response to new challenges facing NASA's robotic solar system exploration program. This volume contains papers presented at the Workshop on Advanced Technologies for Planetary Instruments on 28-30 Apr. 1993. This meeting was conceived in response to new challenges facing NASA's robotic solar system exploration program. Over the past several years, SDIO has sponsored a significant technology development program aimed, in part, at the production of instruments with these characteristics. This workshop provided an opportunity for specialists from the planetary science and DoD communities to establish contacts, to explore common technical ground in an open forum, and more specifically, to discuss the applicability of SDIO's technology base to planetary science instruments.

Exploring the potential of Product Service Systems to achieve household waste prevention on new housing developments in the UK.

PubMed

Gottberg, Annika; Longhurst, Philip J; Cook, Matthew B

2010-03-01

Product service systems (PSS) are cleaner product concepts which have been developed to achieve improvements in resource productivity which may be realized from modern trends in service delivery. However, there is a paucity of research on the waste prevention performance of PSS in UK household markets. This paper reports the findings of exploratory research which begins to address this gap in knowledge. An exploratory waste prevention assessment was completed on four experimental PSS which were developed in conjunction with a major UK house-builder for delivery on their new housing developments. The results of the assessment show that the selected PSS concepts have potential to prevent high value and harmful Waste Electrical and Electronic Equipment (WEEE) arising in UK household waste streams. Consistent with the canon of exploratory research, the assessment also identifies a number of factors which are thought to influence PSS waste prevention performance. It is recognized that further research is needed to gain an in-depth understanding of these factors as well as to define policy measures which enable the conditions in which PSS prevent household waste on new housing developments in the UK to be created.

Green Aerospace Fuels from Nonpetroleum Sources

NASA Technical Reports Server (NTRS)

Hepp, Aloysius F.; Kulis, Michael J.; DeLaRee, Ana B.; Zubrin, Robert; Berggren, Mark; Hensel, Joseph D.; Kimble, Michael C.

2011-01-01

Efforts to produce green aerospace propellants from nonpetroleum sources are outlined. The paper begins with an overview of feedstock processing and relevant small molecule or C1 chemistry. Gas-to-liquid technologies, notably Fischer-Tropsch (FT) processing of synthesis gas (CO and H2), are being optimized to enhance the fraction of product stream relevant to aviation (and other transportation) fuels at the NASA Glenn Research Center (GRC). Efforts to produce optimized catalysts are described. Given the high cost of space launch, the recycling of human metabolic and plastic wastes to reduce the need to transport consumables to orbit to support the crew of a space station has long been recognized as a high priority. If the much larger costs of transporting consumables to the Moon or beyond are taken into account, the importance of developing waste recycling systems becomes still more imperative. One promising way to transform organic waste products into useful gases is steam reformation; this well-known technology is currently being optimized by a Colorado company for exploration and planetary surface operations. Reduction of terrestrial waste streams while producing energy and/or valuable raw materials is an opportunity being realized by a new generation of visionary entrepreneurs. A technology that has successfully demonstrated production of fuels and related chemicals from waste plastics developed in Northeast Ohio is described. Technologies being developed by a Massachusetts company to remove sulfur impurities are highlighted. Common issues and concerns for nonpetroleum fuel production are emphasized. Energy utilization is a concern for production of fuels whether a terrestrial operation or on the lunar (or Martian) surface; the term green relates to not only mitigating excess carbon release but also to the efficiency of grid-energy usage. For space exploration, energy efficiency can be an essential concern. Other issues of great concern include minimizing impurities in the product stream(s), especially those that potential health risks and/or could degrade operations through catalyst poisoning or equipment damage. The potential impacts on future missions by such concerns are addressed in closing.

Saccharomyces cerevisiae strains for second-generation ethanol production: from academic exploration to industrial implementation.

PubMed

Jansen, Mickel L A; Bracher, Jasmine M; Papapetridis, Ioannis; Verhoeven, Maarten D; de Bruijn, Hans; de Waal, Paul P; van Maris, Antonius J A; Klaassen, Paul; Pronk, Jack T

2017-08-01

The recent start-up of several full-scale 'second generation' ethanol plants marks a major milestone in the development of Saccharomyces cerevisiae strains for fermentation of lignocellulosic hydrolysates of agricultural residues and energy crops. After a discussion of the challenges that these novel industrial contexts impose on yeast strains, this minireview describes key metabolic engineering strategies that have been developed to address these challenges. Additionally, it outlines how proof-of-concept studies, often developed in academic settings, can be used for the development of robust strain platforms that meet the requirements for industrial application. Fermentation performance of current engineered industrial S. cerevisiae strains is no longer a bottleneck in efforts to achieve the projected outputs of the first large-scale second-generation ethanol plants. Academic and industrial yeast research will continue to strengthen the economic value position of second-generation ethanol production by further improving fermentation kinetics, product yield and cellular robustness under process conditions. © FEMS 2017.

Dual use technology -- it's good for everyone

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schario, K.

1998-07-01

Dual use technology is defined as technology that has both military and commercial applications. The main benefit to dual use technology is that it encourages research and development (R and D) partnerships between the government and industry that lead to the development of common products for military and commercial purposes instead of application-unique products, as in the past. Commonality, in turn, leads to better, more affordable products for all. These partnerships are cost-shared so that neither party has to bear the entire cost of development. Why is this good? Neither the military nor commercial world can afford to fully fundmore » all R and D efforts required to maintain their technological edge in the international market. How do you determine which R and D programs have enough commercial potential to motivate industry to invest in the development? This paper explores the issues involved in establishing a dual use program, and how to take advantage of the flexibility of these programs.« less

Saccharomyces cerevisiae strains for second-generation ethanol production: from academic exploration to industrial implementation

PubMed Central

Jansen, Mickel L. A.; Bracher, Jasmine M.; Papapetridis, Ioannis; Verhoeven, Maarten D.; de Bruijn, Hans; de Waal, Paul P.; van Maris, Antonius J. A.; Klaassen, Paul

2017-01-01

Abstract The recent start-up of several full-scale ‘second generation’ ethanol plants marks a major milestone in the development of Saccharomyces cerevisiae strains for fermentation of lignocellulosic hydrolysates of agricultural residues and energy crops. After a discussion of the challenges that these novel industrial contexts impose on yeast strains, this minireview describes key metabolic engineering strategies that have been developed to address these challenges. Additionally, it outlines how proof-of-concept studies, often developed in academic settings, can be used for the development of robust strain platforms that meet the requirements for industrial application. Fermentation performance of current engineered industrial S. cerevisiae strains is no longer a bottleneck in efforts to achieve the projected outputs of the first large-scale second-generation ethanol plants. Academic and industrial yeast research will continue to strengthen the economic value position of second-generation ethanol production by further improving fermentation kinetics, product yield and cellular robustness under process conditions. PMID:28899031

Processing of Space Resources to Enable the Vision for Space Exploration

NASA Technical Reports Server (NTRS)

Curreri, Peter A.

2006-01-01

The NASA human exploration program as directed by the Vision for Exploration (G.W. Bush, Jan. 14,2004) includes developing methods to process materials on the Moon and beyond to enable safe and affordable human exploration. Processing space resources was first popularized (O Neill 1976) as a technically viable, economically feasible means to build city sized habitats and multi GWatt solar power satellites in Earth/Moon space. Although NASA studies found the concepts to be technically reasonable in the post Apollo era (AMES 1979), the front end costs the limits of national or corporate investment. In the last decade analysis of space on has shown it to be economically justifiable even on a relatively small mission or commercial scenario basis. The Mars Reference Mission analysis (JSC 1997) demonstrated that production of return propellant on Mars can enable an order of magnitude decrease in the costs of human Mars missions. Analysis (by M. Duke 2003) shows that production of propellant on the Moon for the Earth based satellite industries can be commercially viable after a human lunar base is established. Similar economic analysis (Rapp 2005) also shows large cost benefits for lunar propellant production for Mars missions and for the use of lunar materials for the production of photovoltaic power (Freundlich 2005). Recent technologies could enable much smaller initial costs, to achieve mass, energy, and life support self sufficiency, than were achievable in the 1970s. If the Exploration Vision program is executed with a front end emphasis on space resources, it could provide a path for human self reliance beyond Earth orbit. This path can lead to an open, non-zero-sum, future for humanity with safer human competition with limitless growth potential. This paper discusses extension of the analysis for space resource utilization, to determine the minimum systems necessary for human self sufficiency and growth off Earth. Such a approach can provide a more compelling and comprehensive path to space resource utilization.

Training for Employment: Social Inclusion, Productivity, and Youth Employment. Human Resources Training and Development: Vocational Guidance and Vocational Training. Report V. International Labour Conference (88th Session, 2000). Fifth Item on the Agenda.

ERIC Educational Resources Information Center

International Labour Office, Geneva (Switzerland).

This report examines the human resources development and training dimensions of the gradual, but inexorable, shift towards knowledge-, skill-, and service-based economies and societies, and the stupendous growth of the information and communications technology sectors. Its four chapters explore the following: (1) globalization, technological…

Potential Exploration, Development, and Production of Oil and Gas Resources, Vandenberg Air Force Base, California

DTIC Science & Technology

1987-12-01

market its acreage for leasing purposes to other oil companies once the EIS is finalized and MRMP is adopted since the permitting process will be...procedures might warrant" means that if oil and gas market conditions were such that they exceeded the assumed "most likely" volumes of oil production...year, 1986. Appropriately, there is an antique market there now. McAdam, McAdam & Smith, and Smith Hardware all proceeded Perozzi on the site. Left is

Alcorn wells bolster Philippines oil production

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-21

This paper reports that Alcorn International Inc., Houston, is producing about 16,500 b/d of oil from West Linapacan A field in the South China Sea off the Philippines. The field's current production alone is more than fivefold the Philippines' total average oil flow of 3,000 b/d in 1991. It's part of a string of oil and gas strikes off Palawan Island that has made the region one of the hottest exploration/development plays in the Asia-Pacific theater.

Retrospective analysis of natural products provides insights for future discovery trends.

PubMed

Pye, Cameron R; Bertin, Matthew J; Lokey, R Scott; Gerwick, William H; Linington, Roger G

2017-05-30

Understanding of the capacity of the natural world to produce secondary metabolites is important to a broad range of fields, including drug discovery, ecology, biosynthesis, and chemical biology, among others. Both the absolute number and the rate of discovery of natural products have increased significantly in recent years. However, there is a perception and concern that the fundamental novelty of these discoveries is decreasing relative to previously known natural products. This study presents a quantitative examination of the field from the perspective of both number of compounds and compound novelty using a dataset of all published microbial and marine-derived natural products. This analysis aimed to explore a number of key questions, such as how the rate of discovery of new natural products has changed over the past decades, how the average natural product structural novelty has changed as a function of time, whether exploring novel taxonomic space affords an advantage in terms of novel compound discovery, and whether it is possible to estimate how close we are to having described all of the chemical space covered by natural products. Our analyses demonstrate that most natural products being published today bear structural similarity to previously published compounds, and that the range of scaffolds readily accessible from nature is limited. However, the analysis also shows that the field continues to discover appreciable numbers of natural products with no structural precedent. Together, these results suggest that the development of innovative discovery methods will continue to yield compounds with unique structural and biological properties.

Challenges in measuring and valuing productivity costs, and their relevance in mood disorders

PubMed Central

Lensberg, Benedikte R; Drummond, Michael F; Danchenko, Natalya; Despiégel, Nicolas; François, Clément

2013-01-01

Lost productivity is often excluded from economic evaluations, which may lead to an underestimation of the societal benefits of treatment. However, there are multiple challenges in reliably estimating and reporting productivity losses. This article explores the main challenges, ie, selecting an appropriate valuation method (ie, human capital, friction cost, or multiplier), avoiding double counting, and accounting for equity. It also discusses the use of presenteeism instruments and their application in clinical trials, with a specific focus on their relevance in individuals with mood disorders. Further research and discussion is required on the development of reliable techniques for measuring and valuing productivity changes due to presenteeism. PMID:24273412

Lessons Learned on Implementing Fault Detection, Isolation, and Recovery (FDIR) in a Ground Launch Environment

NASA Technical Reports Server (NTRS)

Ferrell, Bob A.; Lewis, Mark E.; Perotti, Jose M.; Brown, Barbara L.; Oostdyk, Rebecca L.; Goetz, Jesse W.

2010-01-01

This paper's main purpose is to detail issues and lessons learned regarding designing, integrating, and implementing Fault Detection Isolation and Recovery (FDIR) for Constellation Exploration Program (CxP) Ground Operations at Kennedy Space Center (KSC). Part of the0 overall implementation of National Aeronautics and Space Administration's (NASA's) CxP, FDIR is being implemented in three main components of the program (Ares, Orion, and Ground Operations/Processing). While not initially part of the design baseline for the CxP Ground Operations, NASA felt that FDIR is important enough to develop, that NASA's Exploration Systems Mission Directorate's (ESMD's) Exploration Technology Development Program (ETDP) initiated a task for it under their Integrated System Health Management (ISHM) research area. This task, referred to as the FDIIR project, is a multi-year multi-center effort. The primary purpose of the FDIR project is to develop a prototype and pathway upon which Fault Detection and Isolation (FDI) may be transitioned into the Ground Operations baseline. Currently, Qualtech Systems Inc (QSI) Commercial Off The Shelf (COTS) software products Testability Engineering and Maintenance System (TEAMS) Designer and TEAMS RDS/RT are being utilized in the implementation of FDI within the FDIR project. The TEAMS Designer COTS software product is being utilized to model the system with Functional Fault Models (FFMs). A limited set of systems in Ground Operations are being modeled by the FDIR project, and the entire Ares Launch Vehicle is being modeled under the Functional Fault Analysis (FFA) project at Marshall Space Flight Center (MSFC). Integration of the Ares FFMs and the Ground Processing FFMs is being done under the FDIR project also utilizing the TEAMS Designer COTS software product. One of the most significant challenges related to integration is to ensure that FFMs developed by different organizations can be integrated easily and without errors. Software Interface Control Documents (ICDs) for the FFMs and their usage will be addressed as the solution to this issue. In particular, the advantages and disadvantages of these ICDs across physically separate development groups will be delineated.

Plant Molecular Farming: Much More than Medicines.

PubMed

Tschofen, Marc; Knopp, Dietmar; Hood, Elizabeth; Stöger, Eva

2016-06-12

Plants have emerged as commercially relevant production systems for pharmaceutical and nonpharmaceutical products. Currently, the commercially available nonpharmaceutical products outnumber the medical products of plant molecular farming, reflecting the shorter development times and lower regulatory burden of the former. Nonpharmaceutical products benefit more from the low costs and greater scalability of plant production systems without incurring the high costs associated with downstream processing and purification of pharmaceuticals. In this review, we explore the areas where plant-based manufacturing can make the greatest impact, focusing on commercialized products such as antibodies, enzymes, and growth factors that are used as research-grade or diagnostic reagents, cosmetic ingredients, and biosensors or biocatalysts. An outlook is provided on high-volume, low-margin proteins such as industrial enzymes that can be applied as crude extracts or unprocessed plant tissues in the feed, biofuel, and papermaking industries.

Plant Molecular Farming: Much More than Medicines

NASA Astrophysics Data System (ADS)

Tschofen, Marc; Knopp, Dietmar; Hood, Elizabeth; Stöger, Eva

2016-06-01

Plants have emerged as commercially relevant production systems for pharmaceutical and nonpharmaceutical products. Currently, the commercially available nonpharmaceutical products outnumber the medical products of plant molecular farming, reflecting the shorter development times and lower regulatory burden of the former. Nonpharmaceutical products benefit more from the low costs and greater scalability of plant production systems without incurring the high costs associated with downstream processing and purification of pharmaceuticals. In this review, we explore the areas where plant-based manufacturing can make the greatest impact, focusing on commercialized products such as antibodies, enzymes, and growth factors that are used as research-grade or diagnostic reagents, cosmetic ingredients, and biosensors or biocatalysts. An outlook is provided on high-volume, low-margin proteins such as industrial enzymes that can be applied as crude extracts or unprocessed plant tissues in the feed, biofuel, and papermaking industries.

Space Resource Utilization: Technologies and Potential Synergism with Terrestrial Mining

NASA Technical Reports Server (NTRS)

Sanders, Gerald B.

2015-01-01

Space Resources and Their Uses: The idea of using resources in space to support human exploration and settlement or for economic development and profit beyond the surface of Earth has been proposed and discussed for decades. Work on developing a method to extract oxygen from lunar regolith started even before humans set foot on the Moon for the first time. The use of space resources, commonly referred to as In Situ Resource Utilization (ISRU), involves the processes and operations to harness and utilize resources in space (both natural and discarded) to create products for subsequent use. Potential space resources include water, solar wind implanted volatiles (hydrogen, helium, carbon, nitrogen, etc.), vast quantities of metals and minerals in extraterrestrial soils, atmospheric constituents, unlimited solar energy, regions of permanent light and darkness, the vacuum and zero-gravity of space itself, trash and waste from human crew activities, and discarded hardware that has completed its primary purpose. ISRU covers a wide variety of concepts, technical disciplines, technologies, and processes. When considering all aspects of ISRU, there are 5 main areas that are relevant to human space exploration and the commercialization of space: 1. Resource Characterization and Mapping, 2. In Situ Consumables Production, 3. Civil Engineering and Construction, 4. In Situ Energy Production and Storage, and 5. In Situ Manufacturing.

Exploring sustainability transitions in households: insights from real-life experiments

NASA Astrophysics Data System (ADS)

Baedeker, Carolin; Buhl, Johannes; Greiff, Kathrin; Hasselkuß, Marco; Liedtke, Christa; Lukas, Melanie

2016-04-01

Societal transformation towards sustainable consumption and production, especially in urban areas, is a key challenge. The design and implementation of sustainable product service systems (PSS) might be the initial point, in which private households play a major role. The Sustainable LivingLab research infrastructure was developed as an experimental setting for investigating consumption and production patterns in private households, especially to explore socio-technical innovations which are helpful to guide sustainability transitions. The suggested presentation describes results of several real-life experiments conducted in German households, e.g. the project SusLabNRW (North-Rhine Westphalia as part of the European SusLabNWE-Project), the EnerTransRuhr project as well as the PATHWAYS project that explore patterns of action, time use, social practices and the related resource use in private households. The presentation gives an overview of the employed methods and analysed data (qualitative interviews, social network analysis, survey on household activities and inventories and a sustainability assessment (resource profiles - MIPS household analysis). Households' resource consumption was calculated in all fields of activity to analyse social practices' impact. The presentation illustrates how aggregated data can inform scenario analysis and concludes with an outlook onto transition pathways at household level and socio-technical innovations in the fields of housing, nutrition and mobility.

ePlant and the 3D data display initiative: integrative systems biology on the world wide web.

PubMed

Fucile, Geoffrey; Di Biase, David; Nahal, Hardeep; La, Garon; Khodabandeh, Shokoufeh; Chen, Yani; Easley, Kante; Christendat, Dinesh; Kelley, Lawrence; Provart, Nicholas J

2011-01-10

Visualization tools for biological data are often limited in their ability to interactively integrate data at multiple scales. These computational tools are also typically limited by two-dimensional displays and programmatic implementations that require separate configurations for each of the user's computing devices and recompilation for functional expansion. Towards overcoming these limitations we have developed "ePlant" (http://bar.utoronto.ca/eplant) - a suite of open-source world wide web-based tools for the visualization of large-scale data sets from the model organism Arabidopsis thaliana. These tools display data spanning multiple biological scales on interactive three-dimensional models. Currently, ePlant consists of the following modules: a sequence conservation explorer that includes homology relationships and single nucleotide polymorphism data, a protein structure model explorer, a molecular interaction network explorer, a gene product subcellular localization explorer, and a gene expression pattern explorer. The ePlant's protein structure explorer module represents experimentally determined and theoretical structures covering >70% of the Arabidopsis proteome. The ePlant framework is accessed entirely through a web browser, and is therefore platform-independent. It can be applied to any model organism. To facilitate the development of three-dimensional displays of biological data on the world wide web we have established the "3D Data Display Initiative" (http://3ddi.org).

Bryological exploration: field-trip based learning to develop competencies of science teacher candidate

NASA Astrophysics Data System (ADS)

Wisanti; Astriani, D.

2018-04-01

The purpose of this study was analyze the competencies of science teacher candidate after the bryological exploration. The intended competence of science teacher candidate was the ability to apply the concept and science ability to explore plant diversity that could be found around the environment.This field trip was conducted by exploring liverworts, hornworts, and mosses as well. This descriptive research was conducted during March until April 2017 at Universitas Negeri Surabaya (UNESA) and Sumber Brantas Arboretum in Malang, as the location of exploration. The subjects of this study were 76 candidate of teachers from science educations department, which is divided into three classes. The competences observed on this study were describing, identifying, collecting specimens, furthermore. The research instruments were observation sheets, product assessment sheets, and response questionnaire. The data were analyzed descriptive-quantitatively, in percentage and then categorized. The results of this study indicated that: the describing skill was categorized as ‘good’ identifying skill and collecting bryophytes was categorized as ‘very good’ and communicating skills was categorized ‘good’. In addition, the teacher candidates gave a very good response to field-trip-based learning. It can be concluded that the bryological exploration can develop the competences of science teacher candidates of Science Education Department of UNESA.

Scientific Software

NASA Technical Reports Server (NTRS)

1995-01-01

The Interactive Data Language (IDL), developed by Research Systems, Inc., is a tool for scientists to investigate their data without having to write a custom program for each study. IDL is based on the Mariners Mars spectral Editor (MMED) developed for studies from NASA's Mars spacecraft flights. The company has also developed Environment for Visualizing Images (ENVI), an image processing system for easily analyzing remotely sensed data written in IDL. The Visible Human CD, another Research Systems product, is the first complete digital reference of photographic images for exploring human anatomy.

Property rights regimes to optimize natural resource use - future CBM development and sustainability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eaton, C.; Ingelson, A.; Knopff, R.

2007-04-01

Property rights regimes that promote sustainable development in the context of coalbed methane (CBM) exploration and production recognize and optimize the value of multiple natural resources including minerals, water, flora, and fauna. Institutional mechanisms that account for and mitigate both the short- and long-term external impacts from CBM development promote sustainability. The long-term potential for a vibrant recreational and tourist economy on a particular landscape may be compromised by overly shortsighted mineral resource extraction.

Solar photovoltaics for development applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shepperd, L.W.; Richards, E.H.

1993-08-01

This document introduces photovoltaic technology to individuals and groups specializing in development activities. Examples of actual installations illustrate the many services supplied by photovoltaic systems in development applications, including water pumping, lighting, health care, refrigeration, communications, and a variety of productive uses. The various aspects of the technology are explored to help potential users evaluate whether photovoltaics can assist them in achieving their organizational goals. Basic system design, financing techniques, and the importance of infrastructure are included, along with additional sources of information and major US photovoltaic system suppliers.

Formulation of US international energy policies

NASA Astrophysics Data System (ADS)

1980-09-01

To find out how the United States develops international energy policy, GAO reviewed five major energy issues covering the period from early 1977 through 1979. The issues are: vulnerabilities to petroleum supply interruptions; long term national security strategy on imported oil prices; export of U.S. oil and gas production equipment and technology to the Soviety Union; World Bank initiatives to assist in financing oil and gas exploration and development in oil-importing developing countries; and the role of gas imports relative to the nation's future sources of gas.

NASA Video Catalog. Supplement 12

NASA Technical Reports Server (NTRS)

2002-01-01

This report lists 1878 video productions from the NASA STI Database. This issue of the NASA Video Catalog cites video productions listed in the NASA STI Database. The videos listed have been developed by the NASA centers, covering Shuttle mission press conferences; fly-bys of planets; aircraft design, testing and performance; environmental pollution; lunar and planetary exploration; and many other categories related to manned and unmanned space exploration. Each entry in the publication consists of a standard bibliographic citation accompanied by an abstract. The listing of the entries is arranged by STAR categories. A complete Table of Contents describes the scope of each category. For users with specific information, a Title Index is available. A Subject Term Index, based on the NASA Thesaurus, is also included. Guidelines for usage of NASA audio/visual material, ordering information, and order forms are also available.

Lessons Learned from Deploying an Analytical Task Management Database

NASA Technical Reports Server (NTRS)

O'Neil, Daniel A.; Welch, Clara; Arceneaux, Joshua; Bulgatz, Dennis; Hunt, Mitch; Young, Stephen

2007-01-01

Defining requirements, missions, technologies, and concepts for space exploration involves multiple levels of organizations, teams of people with complementary skills, and analytical models and simulations. Analytical activities range from filling a To-Be-Determined (TBD) in a requirement to creating animations and simulations of exploration missions. In a program as large as returning to the Moon, there are hundreds of simultaneous analysis activities. A way to manage and integrate efforts of this magnitude is to deploy a centralized database that provides the capability to define tasks, identify resources, describe products, schedule deliveries, and generate a variety of reports. This paper describes a web-accessible task management system and explains the lessons learned during the development and deployment of the database. Through the database, managers and team leaders can define tasks, establish review schedules, assign teams, link tasks to specific requirements, identify products, and link the task data records to external repositories that contain the products. Data filters and spreadsheet export utilities provide a powerful capability to create custom reports. Import utilities provide a means to populate the database from previously filled form files. Within a four month period, a small team analyzed requirements, developed a prototype, conducted multiple system demonstrations, and deployed a working system supporting hundreds of users across the aeros pace community. Open-source technologies and agile software development techniques, applied by a skilled team enabled this impressive achievement. Topics in the paper cover the web application technologies, agile software development, an overview of the system's functions and features, dealing with increasing scope, and deploying new versions of the system.

Evaluation of a moderate resolution, satellite-based impervious surface map using an independent, high-resolution validation data set

USGS Publications Warehouse

Jones, J.W.; Jarnagin, T.

2009-01-01

Given the relatively high cost of mapping impervious surfaces at regional scales, substantial effort is being expended in the development of moderate-resolution, satellite-based methods for estimating impervious surface area (ISA). To rigorously assess the accuracy of these data products high quality, independently derived validation data are needed. High-resolution data were collected across a gradient of development within the Mid-Atlantic region to assess the accuracy of National Land Cover Data (NLCD) Landsat-based ISA estimates. Absolute error (satellite predicted area - "reference area") and relative error [satellite (predicted area - "reference area")/ "reference area"] were calculated for each of 240 sample regions that are each more than 15 Landsat pixels on a side. The ability to compile and examine ancillary data in a geographic information system environment provided for evaluation of both validation and NLCD data and afforded efficient exploration of observed errors. In a minority of cases, errors could be explained by temporal discontinuities between the date of satellite image capture and validation source data in rapidly changing places. In others, errors were created by vegetation cover over impervious surfaces and by other factors that bias the satellite processing algorithms. On average in the Mid-Atlantic region, the NLCD product underestimates ISA by approximately 5%. While the error range varies between 2 and 8%, this underestimation occurs regardless of development intensity. Through such analyses the errors, strengths, and weaknesses of particular satellite products can be explored to suggest appropriate uses for regional, satellite-based data in rapidly developing areas of environmental significance. ?? 2009 ASCE.

Interspecies interactions that result in Bacillus subtilis forming biofilms are mediated mainly by members of its own genus.

PubMed

Shank, Elizabeth A; Klepac-Ceraj, Vanja; Collado-Torres, Leonardo; Powers, Gordon E; Losick, Richard; Kolter, Roberto

2011-11-29

Many different systems of bacterial interactions have been described. However, relatively few studies have explored how interactions between different microorganisms might influence bacterial development. To explore such interspecies interactions, we focused on Bacillus subtilis, which characteristically develops into matrix-producing cannibals before entering sporulation. We investigated whether organisms from the natural environment of B. subtilis--the soil--were able to alter the development of B. subtilis. To test this possibility, we developed a coculture microcolony screen in which we used fluorescent reporters to identify soil bacteria able to induce matrix production in B. subtilis. Most of the bacteria that influence matrix production in B. subtilis are members of the genus Bacillus, suggesting that such interactions may be predominantly with close relatives. The interactions we observed were mediated via two different mechanisms. One resulted in increased expression of matrix genes via the activation of a sensor histidine kinase, KinD. The second was kinase independent and conceivably functions by altering the relative subpopulations of B. subtilis cell types by preferentially killing noncannibals. These two mechanisms were grouped according to the inducing strain's relatedness to B. subtilis. Our results suggest that bacteria preferentially alter their development in response to secreted molecules from closely related bacteria and do so using mechanisms that depend on the phylogenetic relatedness of the interacting bacteria.

Exploration-Related Research on ISS: Connecting Science Results to Future Missions

NASA Technical Reports Server (NTRS)

Rhatigan, Jennifer L.; Robinson, Julie A.; Sawin, Charles F.

2005-01-01

In January, 2004, the U.S. President announced The Vision for Space Exploration, and charged the National Aeronautics and Space Administration (NASA) with using the International Space Station (ISS) for research and technology targeted at supporting U.S. space exploration goals. This paper describes: What we have learned from the first four years of research on ISS relative to the exploration mission; The on-going research being conducted in this regard; and Our current understanding of the major exploration mission risks that the ISS can be used to address. Specifically, we discuss research carried out on the ISS to determine the mechanisms by which human health is affected on long-duration missions, and to develop countermeasures to protect humans from the space environment. These bioastronautics experiments are key enablers of future long duration human exploration missions. We also discuss how targeted technological developments can enable mission design trade studies. We discuss the relationship between the ultimate number of human test subjects available on the ISS to the quality and quantity of scientific insight that can be used to reduce health risks to future explorers. We discuss the results of NASA's efforts over the past year to realign the ISS research programs to support a product-driven portfolio that is directed towards reducing the major risks of exploration missions. The fundamental challenge to science on ISS is completing experiments that answer key questions in time to shape design decisions for future exploration. In this context, exploration relevant research must do more than be conceptually connected to design decisions - it must become a part of the mission design process.

Institute of Navigation, Annual Meeting, 47th, Williamsburg, VA, June 10-12, 1991, Proceedings

NASA Astrophysics Data System (ADS)

1991-11-01

The present volume of navigation and exploration discusses space exploration, mapping and geodesy, aircraft navigation, undersea navigation, land and vehicular location, international and legal aspects of navigation, the history of navigation technology and applications, Loran development and implementation, GPS and GLONASS developments, and search and rescue. Topics addressed include stabilization of low orbiting spacecraft using GPS, the employment of laser navigation for automatic rendezvous and docking systems, enhanced pseudostatic processing, and the expanding role of sensor fusion. Attention is given to a gravity-aided inertial navigation system, recent developments in aviation products liability and navigation, the ICAO future air navigation system, and Loran's implementation in NAS. Also discussed are Inmarsat integrated navigation/communication activities, the GPS program status, the evolution of military GPS technology into the Navcore V receiver engine, and Sarsat location algorithms.

British firms mark progress off Viet Nam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-11-23

British companies are making more inroads in exploring for oil and gas off Viet Nam. British Gas plc won a 25 year production sharing contract for a license off southern Viet Nam in the South China Sea. Meantime, London independent Lasmo plc started seismic surveys on the block adjoining the British Gas block. Separately, Thailand and Viet Nam have reached agreement to jointly explore for and develop oil and gas found in waters claimed by both countries. Plans call for the two countries to draw up joint development plans covering oil and gas resources in the southeastern fringe of themore » Gulf of Thailand. Bangkok officials say they would have preferred to delineate maritime boundaries with Hanoi, but opted for the joint development accord, noting that Thailand and Malaysia had taken 12 years to resolve a similar dispute.« less

Considerations for development of countermeasures for physiological decrements associated with long-duration space missions

NASA Astrophysics Data System (ADS)

Sawin, Charles F.; Hayes, Judith; Francisco, David R.; House, Nancy

2007-02-01

Countermeasures are necessary to offset or minimize the deleterious changes in human physiology resulting from long duration space flight. Exposure to microgravity alters musculoskeletal, neurosensory, and cardiovascular systems with resulting deconditioning that may compromise crew health and performance. Maintaining health and fitness at acceptable levels is critical for preserving performance capabilities required to accomplish specific mission tasks (e.g.—extravehicular activity) and to optimize performance after landing. To enable the goals of the exploration program, NASA is developing a new suite of exercise hardware such as the improved loading device, the SchRED. This presentation will update the status of current countermeasures, correlate hardware advances with improvements in exercise countermeasures, and discuss future activities for safe and productive exploration missions.

Innovations in Wood Protection in the age of Nanotechnology

Treesearch

Carol A. Clausen

2014-01-01

Advances in wood protection based on nanotechnology are being developed to improve resistance of wood products to biodeterioration, reduce environmental impacts from chemical leaching and resist UV degradation of in-service wood. A number of different approaches have been explored. First, the nanometals zinc oxide and copper oxide were evaluated as preservative...

Determinants of R and D Compensation Strategies in the High Tech Industry.

ERIC Educational Resources Information Center

Balkin, David B.; Gomez-Mejia, Luis R.

1984-01-01

Interviewed managers in high technology and traditional firms (N=105) to explore the determinants of research and development compensation practices and policies in high technology firms. Results indicated that sales volume, stage in the product life cycle, profitabilty, and turnover are predictors of the method and magnitude of financial rewards.…

"Economists Who Think like Ecologists": Reframing Systems Thinking in Games for Learning

ERIC Educational Resources Information Center

DeVane, Ben; Durga, Shree; Squire, Kurt

2010-01-01

Over the past several years, educators have been exploring the potential of immersive interactive simulations, or video games for education, finding that games can support the development of disciplinary knowledge, systemic thinking, the production of complex multimodal digital artifacts, and participation in affinity spaces or sites of collective…

Community Gardening Project: Meredith College Students Explore Sustainability, Organics

ERIC Educational Resources Information Center

Roubanis, Jody L.; Landis, William

2007-01-01

Consuming locally grown foods promotes sustainable development and individual wellness (Waters, 2006). In the United States, the average food product travels 2,000 miles before reaching the consumer (Schlosser, 2001). This distance between producer and consumer is one reason that today's youth lack an understanding of the origin of the food they…

Algae, Electronics and Ginger Beer: Explorations in Biotechnology at the Governor's School.

ERIC Educational Resources Information Center

Wells, John; And Others

1992-01-01

Describes a variety of projects that were used in a summer program for gifted high school students to help teach biotechnical concepts and applications. Presents six projects utilizing algae as tool for solving problems. Also presents five production-oriented projects with hydroponics and fermentation as research and development themes. (PR)

Comparative Education. ASHE Reader Series.

ERIC Educational Resources Information Center

Kempner, Ken, Ed.; Mollis, Marcela, Ed.; Tierney, William G., Ed.

The chapters in this collection explore why particular national higher education systems operate as they do and the effects these systems have on one another, on national and global development, and on the production of knowledge. The works included in this reader address the assessment of inputs and outputs of institutions and the meaning these…

An Investigation of Coopetitive Pedagogic Design for Knowledge Creation in Web-Based Learning

ERIC Educational Resources Information Center

Fu, Fong-Ling; Wu, Ya-Ling; Ho, Hsi-Chuan

2009-01-01

Information and communication technologies (ICTs) have created a supportive environment for collaborative learning at the expense of student motivation and engagement. This study attempts to explore the development of a productive learning atmosphere in the context of Web-based learning. An experiment is conducted with university-level students…

Pan-American Health Organization CD-ROM Pilot Project.

ERIC Educational Resources Information Center

Brito, Claudio J.

1987-01-01

Examines the difficulties faced by the implementors of information dissemination systems in developing nations and explores the possible use of optical data disk technologies to overcome them. A pilot project of the Pan American Health Organization for the production of a CD-ROM containing bibliographic references on public health is described.…

The Role of Group Regulation in Student Groups: A Pedagogical Exploration

ERIC Educational Resources Information Center

Harris, Garth; Bristow, Dennis

2016-01-01

When tasked with group projects, students often struggle with teamwork and tend to overlook the importance of group self-regulation and its role in effective collaborative work. The pedagogy was implemented in semester long university level new product development courses. The pedagogy illustrates how educators can use student generated weekly…

Knowledge Production within the Innovation System: A Case Study from the United Kingdom

ERIC Educational Resources Information Center

Wilson-Medhurst, Sarah

2010-01-01

This paper focuses on a key issue for university managers, educational developers and teaching practitioners: that of producing new operational knowledge in the innovation system. More specifically, it explores the knowledge required to guide individual and institutional styles of teaching and learning in a large multi-disciplinary faculty. The…

Actions Speak! (Louder than Words). The Social and Environmental Impact of Solid Waste.

ERIC Educational Resources Information Center

Peters, Thomas T.; Wissmann, Janet L.

This curriculum guide is designed to help teachers in the middle grades facilitate student understanding of the social and environmental implications and limitations of technological development. The nine activities offer students opportunities to explore social issues arising from the science and technology of the production and management of…

Facilitating Digital Video Production in the Language Arts Curriculum

ERIC Educational Resources Information Center

McKenney, Susan; Voogt, Joke

2011-01-01

Two studies were conducted to facilitate the development of feasible support for the process of integrating digital video making activities in the primary school language arts curriculum. The first study explored which teaching supports would be necessary to enable primary school children to create digital video as a means of fostering…

Explorations of roundwood technology in buildings

Treesearch

Jeffrey Cook

2001-01-01

A report and critical commentary is presented on the use of small diameter roundwood in building construction in the United States and England. Examples are discussed of roundwood joinery being evaluated at the USDA Forest Service's Forest Products Laboratory, and joinery developed by the British engineering consulting firm Buro Happold, working over 15 years in...

Lifting as We Climb: Developing Constellations of Learning within an Informal Online Radio Format

ERIC Educational Resources Information Center

Mistry, Margaret Egan

2012-01-01

This mixed-methods study combines the sociocultural theories of Vygotsky's research on thought and language, Mezirow's Transformational Learning Theory, situated learning theory of Rogoff, Lave, and Wenger, to explore individual and group process and resulting products within an online university radio station system. The study…

15 CFR 930.73 - OCS plan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false OCS plan. 930.73 Section 930.73...) Exploration, Development and Production Activities § 930.73 OCS plan. (a) The term “OCS plan” means any plan... described in detail in OCS plans approved by the Secretary of the Interior or designee prior to management...

Exploring Market and Competitive Intelligence Research as a Source for Enhancing Innovation Capacity

ERIC Educational Resources Information Center

Bajaj, Deepak

2015-01-01

The purpose of this study was to assess the role of Competitive and Market Intelligence (CI/MI) Research as a potential source for improving the innovation capability of Small and Medium Enterprises (SME's) leading to successful new product/services/processes/capabilities development (Cooper & Edgett, 2002). This report highlights the…

Studying Language Learning Opportunities Afforded by a Collaborative CALL Task

ERIC Educational Resources Information Center

Leahy, Christine

2016-01-01

This research study explores the learning potential of a computer-assisted language learning (CALL) activity. Research suggests that the dual emphasis on content development and language accuracy, as well as the complexity of L2 production in natural settings, can potentially create cognitive overload. This study poses the question whether, and…

China Report, Economic Affairs

DTIC Science & Technology

1985-02-02

40 Briefs Shanghai Food Industry Production 41 Jiangsu’s Industrial Output Value 41 CONSTRUCTION JINGJI RIBAO Urges Putting Construction First... industry , such as electronics, building materials, chemicals, 13 food and tailoring industries ; communications, such as passenger transportation; as...encourage these enterprises to develop the food , animal feed processing, construction, building materials and energy exploration industries , and help them

Project-Method Fit: Exploring Factors That Influence Agile Method Use

ERIC Educational Resources Information Center

Young, Diana K.

2013-01-01

While the productivity and quality implications of agile software development methods (SDMs) have been demonstrated, research concerning the project contexts where their use is most appropriate has yielded less definitive results. Most experts agree that agile SDMs are not suited for all project contexts. Several project and team factors have been…

Gents, Jerks, and Jocks: What Male Students Learn about Masculinity in College

ERIC Educational Resources Information Center

Harris, Frank, III; Struve, Laura E.

2009-01-01

The academy plays a significant role in male students' experience of gender. In this article, the authors explore how educators can effectively support healthy and productive gender identity development among college men. Their goal is to provide insight into how campus cultures convey and reinforce lessons about what constitutes "normal"…

Traditional Craft or Technology Education: Development of Students' Technical Abilities in Finnish Comprehensive School

ERIC Educational Resources Information Center

Autio, Ossi

2016-01-01

Changes in the economy, nature, production and society together with increasing scientific and technological knowledge make demands of transforming school teaching in the field of technology education. The aim of the article is briefly to explore the integration between science, technology and traditional craft education by analyzing the current…

77 FR 13200 - Texas: Final Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

....1. Such wastes are termed ``oil and gas wastes.'' The TCEQ has responsibility to administer the RCRA program, however, hazardous waste generated at natural gas or natural gas liquids processing plants or... with the exploration, development, or production of oil or gas or geothermal resources and other...

Paul Mills Ireland III Portrait of a Soldier

ERIC Educational Resources Information Center

Dolan, John P.

2013-01-01

This dissertation explores the life and identity of Paul Mills Ireland, III. The qualitative study was conducted using the portraiture approach and was further developed by incorporating the holistic content approach of analysis in narrative research. This fifth generation soldier was the product of a strong military lineage, most of whom were…

Collaborative e-Learning: e-Portfolios for Assessment, Teaching and Learning

ERIC Educational Resources Information Center

Luchoomun, Dharmadeo; McLuckie, Joe; van Wesel, Maarten

2010-01-01

This paper presents an innovative approach to e-learning by exploring a number of initiatives where there is a move towards collaborative use of Personal Development Plans (PDPs) integrated with e-portfolios as mechanisms for delivering such plans. It considers whether such a move towards more product orientated assessment might enhance student…

Toward More Precise Definition and Evaluation of Televised Educational Programming

ERIC Educational Resources Information Center

Aversa Fran; Morrison, Gary R.

1978-01-01

An operational definition of public television programming and its implications for development and production agencies is sorely needed. This article explores some of the components of such a definition and examines the differences in several types of educational programming in terms of specific design and evaluation variables of the program.…

Instructivist Ideology: Education Technology Embracing the Past?

ERIC Educational Resources Information Center

Amory, Alan

2012-01-01

It is argued that against the background of a neo-managerial and market-driven global education system, the production and use of technology to support teaching and learning perpetuates hegemonic behaviorist values. Activity theory, as a lens, is used to explore the power relations that are integral to the development and use of Reusable Learning…

Disciplinary Literacies in an Engineering Club: Exploring Productive Communication and the Engineering Design Process

ERIC Educational Resources Information Center

Shanahan, Lynn E.; McVee, Mary B.; Slivestri, Katarina N.; Haq, Kate

2016-01-01

This conceptual article addresses the question: What are the disciplinary literacy practices surrounding the Engineering Design Process (EDP) at the elementary level? Recent attention has focused on developing science, technology, engineering, and math (STEM) skills for U.S. students. In the United States, the Next Generation Science Standards and…

Exploring seed oil biosynthetic pathway in lesquerella (Physaria fendleri), an important industrial crop

USDA-ARS?s Scientific Manuscript database

Lesquerella is currently being developed as a new industrial oilseed. Lesquerella is valued for its unusual hydroxy fatty acid (HFA), lesquerolic acid (20:1OH), which can be used as raw materials for numerous industrial products, such as lubricants, plasticizers and surfactants. As a step towards ge...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Springmeyer, R R; Brugger, E; Cook, R

The Data group provides data analysis and visualization support to its customers. This consists primarily of the development and support of VisIt, a data analysis and visualization tool. Support ranges from answering questions about the tool, providing classes on how to use the tool, and performing data analysis and visualization for customers. The Information Management and Graphics Group supports and develops tools that enhance our ability to access, display, and understand large, complex data sets. Activities include applying visualization software for large scale data exploration; running video production labs on two networks; supporting graphics libraries and tools for end users;more » maintaining PowerWalls and assorted other displays; and developing software for searching and managing scientific data. Researchers in the Center for Applied Scientific Computing (CASC) work on various projects including the development of visualization techniques for large scale data exploration that are funded by the ASC program, among others. The researchers also have LDRD projects and collaborations with other lab researchers, academia, and industry. The IMG group is located in the Terascale Simulation Facility, home to Dawn, Atlas, BGL, and others, which includes both classified and unclassified visualization theaters, a visualization computer floor and deployment workshop, and video production labs. We continued to provide the traditional graphics group consulting and video production support. We maintained five PowerWalls and many other displays. We deployed a 576-node Opteron/IB cluster with 72 TB of memory providing a visualization production server on our classified network. We continue to support a 128-node Opteron/IB cluster providing a visualization production server for our unclassified systems and an older 256-node Opteron/IB cluster for the classified systems, as well as several smaller clusters to drive the PowerWalls. The visualization production systems includes NFS servers to provide dedicated storage for data analysis and visualization. The ASC projects have delivered new versions of visualization and scientific data management tools to end users and continue to refine them. VisIt had 4 releases during the past year, ending with VisIt 2.0. We released version 2.4 of Hopper, a Java application for managing and transferring files. This release included a graphical disk usage view which works on all types of connections and an aggregated copy feature for quickly transferring massive datasets quickly and efficiently to HPSS. We continue to use and develop Blockbuster and Telepath. Both the VisIt and IMG teams were engaged in a variety of movie production efforts during the past year in addition to the development tasks.« less

The Traditional Medicine and Modern Medicine from Natural Products.

PubMed

Yuan, Haidan; Ma, Qianqian; Ye, Li; Piao, Guangchun

2016-04-29

Natural products and traditional medicines are of great importance. Such forms of medicine as traditional Chinese medicine, Ayurveda, Kampo, traditional Korean medicine, and Unani have been practiced in some areas of the world and have blossomed into orderly-regulated systems of medicine. This study aims to review the literature on the relationship among natural products, traditional medicines, and modern medicine, and to explore the possible concepts and methodologies from natural products and traditional medicines to further develop drug discovery. The unique characteristics of theory, application, current role or status, and modern research of eight kinds of traditional medicine systems are summarized in this study. Although only a tiny fraction of the existing plant species have been scientifically researched for bioactivities since 1805, when the first pharmacologically-active compound morphine was isolated from opium, natural products and traditional medicines have already made fruitful contributions for modern medicine. When used to develop new drugs, natural products and traditional medicines have their incomparable advantages, such as abundant clinical experiences, and their unique diversity of chemical structures and biological activities.

Integrated knowledge translation: digging deeper, moving forward.

PubMed

Kothari, Anita; Wathen, C Nadine

2017-06-01

Integrated knowledge translation has risen in popularity as a solution to the underuse of research in policy and practice settings. It engages knowledge users-policymakers, practitioners, patients/consumers or their advocates, and members of the wider public-in mutually beneficial research that can involve the joint development of research questions, data collection, analysis and dissemination of findings. Knowledge that is co-produced has a better chance of being implemented. The purpose of this paper is to update developments in the field of integrated knowledge translation through a deeper analysis of the approach in practice-oriented and policy-oriented health research. We present collaborative models that fall outside the scope of integrated knowledge translation, but then explore consensus-based approaches and networks as alternate sites of knowledge co-production. We discuss the need to advance the field through the development, or use, of data collection and interpretation tools that creatively engage knowledge users in the research process. Most importantly, conceptually relevant outcomes need to be identified, including ones that focus on team transformation through the co-production of knowledge. We explore some of these challenges and benefits in detail to help researchers understand what integrated knowledge translation means, and whether the approach's potential added value is worth the investment of time, energy and other resources. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Engineering low-temperature expression systems for heterologous production of cold-adapted enzymes.

PubMed

Bjerga, Gro Elin Kjæreng; Lale, Rahmi; Williamson, Adele Kim

2016-01-01

Production of psychrophilic enzymes in the commonly used mesophilic expression systems is hampered by low intrinsic stability of the recombinant enzymes at the optimal host growth temperatures. Unless strategies for low-temperature expression are advanced, research on psychrophilic enzymes may end up being biased toward those that can be stably produced in commonly used mesophilic host systems. Two main strategies are currently being explored for the development of low-temperature expression in bacterial hosts: (i) low-temperature adaption of existing mesophilic expression systems, and (ii) development of new psychrophilic hosts. These developments include genetic engineering of the expression cassettes to optimize the promoter/operator systems that regulate heterologous expression. In this addendum we present our efforts in the development of such low-temperature expression systems, and speculate about future advancements in the field and potential applications.

Coso: Example of a Complex Geothermal Reservoir.

DTIC Science & Technology

1985-09-01

regarding the structural setting, origin, and internal structure of this energy resource. Because of accelerating exploration and development drilling that is... drilling targets and productivity estimates that can be tested as the resource is developed. Like virtually all resources, Coso will be drilled and tested...73 47. Idealized Cross Section Through Red Mountain Type of Pipe ................... 74 48. Results of Drilling Wells 75-7, 75A-7, 75B-7, 15-8, and

Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Appel, Aaron M.; Bercaw, John E.; Bocarsly, Andrew B.

2013-08-14

Our central premise is that catalytic scientists can learn by studying how these important metabolic processes occur in nature. Complementarily, biochemists can learn by studying how catalytic scientists view these same chemical transformations promoted by synthetic catalysts. From these studies, hypotheses can be developed and tested through manipulation of enzyme structure and by synthesizing simple molecular catalysts to incorporate different structural features of the enzymes. It is hoped that these studies will lead to new and useful concepts in catalyst design for fuel production and utilization. This paper describes the results of a workshop held to explore these concepts inmore » regard to the development of new and more efficient catalytic processes for the conversion of CO2 to a variety of carbon-based fuels. The organization of this overview/review is as follows: 1) The first section briefly explores how interactions between the catalysis and biological communities have been fruitful in developing new catalysts for the reduction of protons to hydrogen, the simplest fuel generation reaction. 2) The second section assesses the state of the art in both biological and chemical reduction of CO2 by two electrons to form either carbon monoxide (CO) or formate (HCOO-). It also attempts to identify common principles between biological and synthetic catalysts and productive areas for future research. 3) The third section explores both biological and chemical processes that result in the reduction of CO2 beyond the level of CO and formate, again seeking to identify common principles and productive areas of future research. 4) The fourth section explores the formation of carbon-carbon bonds in biological and chemical systems in the same vein as the other sections. 5) A fifth section addresses the role of non-redox reactions of CO2 in biological systems and their role in carbon metabolism, with a parallel discussion of chemical systems. 6) In section 6, the topics of electrode modification, photochemical systems, and tandem catalysis are briefly discussed. These areas may be important for developing practical systems for CO2 reduction, and they share the common theme of coupling chemical reactions. 7) Section 7 describes some of the crosscutting activities that are critical for advancing the science underpinning catalyst development. 8) The last section attempts to summarize common issues in biological and chemical catalysis and to identify challenges that must be addressed to achieve practical catalysts that are suitable for the reduction of CO2 to fuels.« less

Annual report

NASA Technical Reports Server (NTRS)

1992-01-01

The overall goal of the Tuskegee University Center for Food Production, Processing and Waste Management in Controlled Ecological Life Support Systems (CELSS) is to provide tested information and technologies applicable to bioregenerative food production systems for life support on long-term manned space mission. Specifically, the center is developing information, computer simulated models, methodologies and technology for sweetpotato and peanut biomass production and processing, inclusive of waste management and recycling of these crops selected by NASA for CELSS. The Center is organized into interdisciplinary teams of life scientists and engineers that work together on specific objectives and long-term goals. Integral to the goal of the Center is the development of both basic and applied research information and the training of young scientists and engineers, especially underrepresented minorities that will increase the professional pool in these disciplines and contribute to the advancement of space sciences and exploration.

Managed Entry Agreements for Pharmaceuticals in the Context of Adaptive Pathways in Europe

PubMed Central

Bouvy, Jacoline C.; Sapede, Claudine; Garner, Sarah

2018-01-01

As per the EMA definition, adaptive pathways is a scientific concept for the development of medicines which seeks to facilitate patient access to promising medicines addressing high unmet need through a prospectively planned approach in a sustainable way. This review reports the findings of activities undertaken by the ADAPT-SMART consortium to identify enablers and explore the suitability of managed entry agreements for adaptive pathways products in Europe. We found that during 2006–2016 outcomes-based managed entry agreements were not commonly used for products with a conditional marketing authorization or authorized under exceptional circumstances. The barriers and enablers to develop workable managed entry agreements models for adaptive pathways products were discussed through interviews and a multi-stakeholder workshop with a number of recommendations made in this paper. PMID:29636692

Alaska looks HOT!

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belcher, J.

Production in Alaska has been sluggish in recent years, with activity in the Prudhoe Bay region in the North Slope on a steady decline. Alaska North Slope (ANS) production topped out in 1988 at 2.037 MMbo/d, with 1.6 MMbo/d from Prudhoe Bay. This year operators expect to produce 788 Mbo/d from Prudhoe Bay, falling to 739 Mbo/d next year. ANS production as a whole should reach 1.3 MMbo/d this year, sliding to 1.29 MMbo/d in 1998. These declining numbers had industry officials and politicians talking about the early death of the Trans-Alaskan Pipeline System-the vital link between ANS crude andmore » markets. But enhanced drilling technology coupled with a vastly improved relationship between the state government and industry have made development in Alaska more economical and attractive. Alaska`s Democratic Gov. Tommy Knowles is fond of telling industry {open_quotes}we`re open for business.{close_quotes} New discoveries on the North Slope and in the Cook Inlet are bringing a renewed sense of optimism to the Alaska exploration and production industry. Attempts by Congress to lift a moratorium on exploration and production activity in the Arctic National Wildlife Refuge (ANWR) have been thwarted thus far, but momentum appears to be with proponents of ANWR drilling.« less

Shared Opportunities on Institutional Lands: On-Site Food Production, Its Benefits, Barriers, and Opportunities.

PubMed

Knezevic, Irena; Mount, Phil; Clement, Chantal

2016-10-01

This article outlines preliminary findings of a 3-year project that explored on-site food production on institutional properties, primarily healthcare facilities. There are growing pressures on healthcare facilities to improve their food offerings and incorporate food gardens into their health programs. While several healthcare facilities produce food on-site, there are few studies that explore opportunities, capacities, and institutional barriers related to on-site food production. The study employed mixed methods including historical review, case studies, surveys, interviews, pilot garden projects, and Geographic Information System mapping. The number of participating institutions varied by method. Benefits associated with on-site food production can be health, economic, environmental, and social. There are also institutional barriers including administrative roadblocks, perceived obstacles, and the difficulty in quantitatively, measuring the qualitatively documented benefits. The benefits of food gardens far outweigh the challenges. On-site food production has tremendous potential to improve nutrition for staff and patients, offer healing spaces, better connect institutions with the communities in which they are located, and provide the long-professed benefits of gardening for all involved-from therapeutic benefits and outdoor physical activities to developing skills and social relationships in ways that few other activities do. © The Author(s) 2016.

Building a discovery partnership with Sarawak Biodiversity Centre: a gateway to access natural products from the rainforests.

PubMed

Yeo, Tiong Chia; Naming, Margarita; Manurung, Rita

2014-03-01

The Sarawak Biodiversity Centre (SBC) is a state government agency which regulates research and promotes the sustainable use of biodiversity. It has a program on documentation of traditional knowledge (TK) and is well-equipped with facilities for natural product research. SBC maintains a Natural Product Library (NPL) consisting of local plant and microbial extracts for bioprospecting. The NPL is a core discovery platform for screening of bioactive compounds by researchers through a formal agreement with clear benefit sharing obligations. SBC aims to develop partnerships with leading institutions and the industries to explore the benefits of biodiversity.

Non-Linear Effects in Knowledge Production

NASA Astrophysics Data System (ADS)

Purica, Ionut

2007-04-01

The generation of technological knowledge is paramount to our present development; the production of technological knowledge is governed by the same Cobb Douglas type model, with the means of research and the intelligence level replacing capital, respectively labor. We are exploring the basic behavior of present days' economies that are producing technological knowledge, along with the `usual' industrial production and determine a basic behavior that turns out to be a `Henon attractor'. Measures are introduced for the gain of technological knowledge and for the information of technological sequences that are based respectively on the underlying multi-valued modal logic of the technological research and on nonlinear thermodynamic considerations.

Sustainable Transportation Fuels from Natural Gas (H{sub 2}), Coal and Biomass

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huffman, Gerald

2012-12-31

This research program is focused primarily on the conversion of coal, natural gas (i.e., methane), and biomass to liquid fuels by Fischer-Tropsch synthesis (FTS), with minimum production of carbon dioxide. A complementary topic also under investigation is the development of novel processes for the production of hydrogen with very low to zero production of CO{sub 2}. This is in response to the nation's urgent need for a secure and environmentally friendly domestic source of liquid fuels. The carbon neutrality of biomass is beneficial in meeting this goal. Several additional novel approaches to limiting carbon dioxide emissions are also being explored.

Fermented meat sausages from game and venison: what are the opportunities and limitations?

PubMed

Chakanya, Chido; Arnaud, Elodie; Muchenje, Voster; Hoffman, Louwrens C

2018-04-10

An increase in the acceptance, demand and production of game meat and venison has been experienced globally. Game meat and venison fit into consumers' ideology of healthy and environmentally friendly meat when compared to domesticated animals. Opportunities exist to explore the use of these meat sources in developing new products, particularly as game meat and venison in their fresh state are sometimes perceived as being tough. Consumers have shown a trend for trying exciting new products with different organoleptic qualities, and fermented sausages occupy a special niche in the gastro-economic trade. In this review, the production potential of game meat and venison and its prospective use in the development of fermented sausages are discussed. Emphasis is placed on the importance of meat characteristics in textural and sensorial development as well as the safety of fermented sausages. Additionally, consumers' perception of venison and game meat is discussed. Possible areas of research and knowledge gaps are highlighted, particularly the potential use of meat with high pH and microbial load. © 2018 Society of Chemical Industry. © 2018 Society of Chemical Industry.

The Consumer Motivation Scale: A detailed review of item generation, exploration, confirmation, and validation procedures.

PubMed

Barbopoulos, I; Johansson, L-O

2017-08-01

This data article offers a detailed description of analyses pertaining to the development of the Consumer Motivation Scale (CMS), from item generation and the extraction of factors, to confirmation of the factor structure and validation of the emergent dimensions. The established goal structure - consisting of the sub-goals Value for Money, Quality, Safety, Stimulation, Comfort, Ethics, and Social Acceptance - is shown to be related to a variety of consumption behaviors in different contexts and for different products, and should thereby prove useful in standard marketing research, as well as in the development of tailored marketing strategies, and the segmentation of consumer groups, settings, brands, and products.

An introduction to the new Productivity Information Management System (PIMS)

NASA Technical Reports Server (NTRS)

Hull, R.

1982-01-01

The productivity information management system (PIMS), is described. The main objective of this computerized system is to enable management scientists to interactively explore data concerning DSN operations, maintenance and repairs, to develop and verify models for management planning. The PIMS will provide a powerful set of tools for iteratively manipulating data sets in a wide variety of ways. The initial version of PIMS will be a small scale pilot system. The following topics are discussed: (1) the motivation for developing PIMS; (2) various data sets which will be integrated by PIMS; (3) overall design of PIMS; and (4) how PIMS will be used. A survey of relevant databases concerning DSN operations at Goldstone is also included.

AuScope research infrastructure - supporting Australian mineral discovery

NASA Astrophysics Data System (ADS)

McInnes, B.; Rawling, T.

2016-12-01

Earth and geospatial scientists are heavy users of data products. When industry geologists access spatial data from the field and the exploration office they require data products that are discoverable, searchable, interoperable and attributed with robust metadata. Over the last decade AuScope has utilised NCRIS funding to provide a variety of data products including geophysical data (reflection and passive seismic, magnetotellurics and gravity), GIS layers from state and national geological survey organisations, hyperspectral core logging (National Virtual Core Library) and time-series geospatial data from GNSS and VLBI instruments - all delivered using AuScope GRID technologies based on the Spatial Information Services Stack (SiSS). Perhaps one of the best examples of collaboration to deliver data products to industry users is the National Mineral Library. Working with researchers at Curtin Universities John de Laeter Centre and ANDS, AuScope has also supported the development of a Laboratory Information Management System (LIMS). The project has produced an entirely new workflow, based around a TESCAN TIMA field emission scanning electron microscope, that allows metadata to be collected and recorded from the sample collection and preparation right through to data delivery and publication. This process has facilitated the scanning of a large stockpile of mineral samples from across Western Australia that will produce a state-wide Mineral Library, allowing mineral explorers to better understand the composition of critical rock outcrop samples from all over the state. This new NCRIS supported initiative provides a dataset that underpins both academic and applied research programs and is important for the economic future of Australia. Mining companies do a lot of heavy mineral analysis in research and development but, because there isn't a baseline for mineralogy across each state, it is difficult to have full confidence in the heavy mineral data. This creates an issue for pinpointing where the next major mineral deposits are. Having solid baseline data will help improve targeting, which in turn reduces the costs associated with exploration and supports new discovery.

Reducing Risk of Salmonellosis through Egg Decontamination Processes.

PubMed

Keerthirathne, Thilini Piushani; Ross, Kirstin; Fallowfield, Howard; Whiley, Harriet

2017-03-22

Eggs have a high nutritional value and are an important ingredient in many food products. Worldwide foodborne illnesses, such as salmonellosis linked to the consumption of eggs and raw egg products, are a major public health concern. This review focuses on previous studies that have investigated the procedures for the production of microbiologically safe eggs. Studies exploring pasteurization and decontamination methods were investigated. Gamma irradiation, freeze drying, hot air, hot water, infra-red, atmospheric steam, microwave heating and radiofrequency heating are all different decontamination methods currently considered for the production of microbiologically safe eggs. However, each decontamination procedure has different effects on the properties and constituents of the egg. The pasteurization processes are the most widely used and best understood; however, they influence the coagulation, foaming and emulsifying properties of the egg. Future studies are needed to explore combinations of different decontamination methods to produce safe eggs without impacting the protein structure and usability. Currently, eggs which have undergone decontamination processes are primarily used in food prepared for vulnerable populations. However, the development of a decontamination method that does not affect egg properties and functionality could be used in food prepared for the general population to provide greater public health protection.

Reducing Risk of Salmonellosis through Egg Decontamination Processes

PubMed Central

Keerthirathne, Thilini Piushani; Ross, Kirstin; Fallowfield, Howard; Whiley, Harriet

2017-01-01

Eggs have a high nutritional value and are an important ingredient in many food products. Worldwide foodborne illnesses, such as salmonellosis linked to the consumption of eggs and raw egg products, are a major public health concern. This review focuses on previous studies that have investigated the procedures for the production of microbiologically safe eggs. Studies exploring pasteurization and decontamination methods were investigated. Gamma irradiation, freeze drying, hot air, hot water, infra-red, atmospheric steam, microwave heating and radiofrequency heating are all different decontamination methods currently considered for the production of microbiologically safe eggs. However, each decontamination procedure has different effects on the properties and constituents of the egg. The pasteurization processes are the most widely used and best understood; however, they influence the coagulation, foaming and emulsifying properties of the egg. Future studies are needed to explore combinations of different decontamination methods to produce safe eggs without impacting the protein structure and usability. Currently, eggs which have undergone decontamination processes are primarily used in food prepared for vulnerable populations. However, the development of a decontamination method that does not affect egg properties and functionality could be used in food prepared for the general population to provide greater public health protection. PMID:28327524

Minimum Equipment Lists, Flight Rules and ... Past, Present and Future of Safety Pre-Determined Decisions for Operations

NASA Astrophysics Data System (ADS)

Herd, A.; Wolff, M.

2012-01-01

Extended mission operations, such as human spaceflight to Mars provide an opportunity for take current human exploration beyond Low Earth Orbit, such as the operations undertaken on the International Space Station (ISS). This opportunity also presents a challenge in terms of extending what we currently understand as "remote operations" performed on ISS, offering learning beyond that gained from the successful moon- lander expeditions. As such there is a need to assess how the existing operations concept of ground support teams directing (and supporting) on-orbit ISS operations can be applied in the extended mission concept. The current mission support concept involves three interacting operations products - a short term plan, crew procedures and flight rules. Flight rules (for ISS operations) currently provide overall planning, engineering and operations constraints (including those derived from a safety perspective) in the form of a rule book. This paper will focus specifically on flight rules, and describe the current use of them, and assess the future role of flight rules to support exploration, including the deployment of decision support tools (DSTs) to ensure flight rule compliancy for missions with minimal ground support. Taking consideration of the historical development of pre-planned decisions, and their manifestation within the operations environment, combined with the extended remoteness of human exploration missions, we will propose a future development of this product and a platform on which it could be presented.

SEG and AAPG: common background, common problems, common future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larner, K.

1989-03-01

Today, products of the geophysical method are considered indispensable for geologic interpretation in petroleum exploration. Few exploration case histories today lack the evidence of seismic data upon which structural and stratigraphic interpretations have been constrained. Likewise, during the deep recession that exploration has been experiencing, exploration geophysicists are increasingly realizing that their tools have value only to the extent that they can yield geological and reservoir information that is more directly relevant to oil finding and field development than in the past. Geophysicists are now preoccupied with more than just their wavelets, static correction, and migration. As the papers inmore » this session indicate, geophysicists are extending their technology to estimate lithology, fluid content, monitoring of EOR efforts, and characterization and development of reservoirs. The three-dimensional seismic method, for example, is being brought right to the borehole with the use of the drill bit as the energy source. The futures of their two societies and their members are fully intertwined. Geologists and petroleum engineers who wish to gain considerably more information, cost-effectively, about their prospects, fields, and reservoirs must stay in touch with the exciting new developments from the geophysical community. Equally, geophysicists can maintain their relevance to oil finding only by staying closely in touch with developments in understanding of geology and the reservoir, and with the working interests and needs of geologists and petroleum engineers.« less

Strategic Options for International Participation in Space Exploration: Lessons from U.S.-Japan Defense Cooperation

NASA Technical Reports Server (NTRS)

Hudiburg, John J.; Chinworth, Michael W.

2005-01-01

The President's Commission on Implementation of United States Space Exploration Policy suggests that after NASA establishes the Space Exploration vision architecture, it should pursue international partnerships. Two possible approaches were suggested: multiple independently operated missions and an integrated mission with carefully selected international components. The U.S.-Japan defense sectors have learned key lessons from experience with both of these approaches. U.S.-Japan defense cooperation has evolved over forty years from simple military assistance programs to more complex joint development efforts. With the evolution of the political-military alliance and the complexity of defense programs, these cooperative efforts have engaged increasingly industrial resources and capabilities as well as more sophisticated forms of planning, technology transfers and program management. Some periods of this evolution have been marked by significant frictions. The U.S.Japan FS-X program, for example, provides a poor example for management of international cooperation. In November 1988, the United States and Japan signed a Memorandum of Understanding (MOU) to co-develop an aircraft, named FS-X and later renamed F -2, as a replacement to the aging Japan support fighter F-l. The program was marked by numerous political disputes. After over a decade of joint development and testing, F -2 production deliveries finally began in 1999. The production run was curtailed due to much higher than anticipated costs and less than desired aircraft performance. One universally agreed "lesson" from the FSX/F-2 case was that it did not represent the ideal approach to bilateral cooperation. More recent cooperative programs have involved targeted joint research and development, including component development for ballistic missile defense systems. These programs could lay the basis for more ambitious cooperative efforts. This study examines both less-than-stellar international cooperation efforts as well as more successful initiatives to identify lessons from military programs that can help NASA encourage global investment in its Space Exploration Vision. The paper establishes a basis for examining related policy and industrial concerns such as effective utilization of dual-use technologies and trans-Pacific program management of large, complex cooperative programs.

Bringing You the Moon: Lunar Education Efforts of the Center for Lunar Science and Education

NASA Technical Reports Server (NTRS)

Shaner, A. J.; Shupla, C.; Shipp, S.; Allen, J.; Kring, D. A.; Halligan, E.; LaConte, K.

2012-01-01

The Center for Lunar Science and Exploration (CLSE), a collaboration between the Lunar and Planetary Institute and NASA's Johnson Space Center, is one of seven member teams of the NASA Lunar Science Institute. In addition to research and exploration activities, the CLSE team is deeply invested in education and public outreach. Overarching goals of CLSE education are to strengthen the future science workforce, attract and retain students in STEM disciplines, and develop advocates for lunar exploration. The team's efforts have resulted in a variety of programs and products, including the creation of a variety of Lunar Traveling Exhibits and the High School Lunar Research Project, featured at http://www.lpi.usra.edu/nlsi/education/.

US Rockies gas focus points up need for access, risk takers, infrastructure

USGS Publications Warehouse

Thomasson, M.R.; Belanger, P.E.; Cook, L.

2004-01-01

The last 20 yr of the Rocky Mountains oil and gas exploration and production business have been turbulent. Most of the major companies have left; they have been replaced with, independents and small to larger private and public companies. Natural gas become the primary focus of exploration. A discussion covers the shift of interest from drilling for oil to gas exploration and development in the Rockies since 1980; resource pyramid, showing relative volumes, reserves, resources, and undiscovered gas; the Wyoming fields that boost US gas supply, i.e., Jonah (6-12 tcf), Pinedale Anticline (10-20 tcf); Big Piney-LaBarge (15-25 tcf), Madden (3-5 tcf), and Powder river (24-27 tcf); and the future.

Energy index decomposition methodology at the plant level

NASA Astrophysics Data System (ADS)

Kumphai, Wisit

Scope and method of study. The dissertation explores the use of a high level energy intensity index as a facility-level energy performance monitoring indicator with a goal of developing a methodology for an economically based energy performance monitoring system that incorporates production information. The performance measure closely monitors energy usage, production quantity, and product mix and determines the production efficiency as a part of an ongoing process that would enable facility managers to keep track of and, in the future, be able to predict when to perform a recommissioning process. The study focuses on the use of the index decomposition methodology and explored several high level (industry, sector, and country levels) energy utilization indexes, namely, Additive Log Mean Divisia, Multiplicative Log Mean Divisia, and Additive Refined Laspeyres. One level of index decomposition is performed. The indexes are decomposed into Intensity and Product mix effects. These indexes are tested on a flow shop brick manufacturing plant model in three different climates in the United States. The indexes obtained are analyzed by fitting an ARIMA model and testing for dependency between the two decomposed indexes. Findings and conclusions. The results concluded that the Additive Refined Laspeyres index decomposition methodology is suitable to use on a flow shop, non air conditioned production environment as an energy performance monitoring indicator. It is likely that this research can be further expanded in to predicting when to perform a recommissioning process.

Exploring Consumer Literacy

ERIC Educational Resources Information Center

Moore, Virginia; Sumrall, William; Mott, Michael; Mitchell, Elizabeth; Theobald, Becky

2015-01-01

Methods for facilitating students' standards-based consumer literacy are addressed via the use of problem solving with food and product labels. Fifth graders will be able to: (1) provide detailed analysis of food and product labels; (2) understand large themes, including production, distribution, and consumption; and (3) explore consumer…

PEER DEVELOPMENT OF UNDERGRADUATE ASTRONOMERS AND PHYSICISTS AT THE UNIVERSITY OF WISCONSIN - MADISON

NASA Astrophysics Data System (ADS)

Abler, Melissa; UW-Madison, Physics Club of

2014-01-01

The physics club at the University of Wisconsin - Madison is actively engaged in many peer-led activities that foster development of career-oriented skills. The Garage Physics program utilizes old, unwanted laboratory equipment to enable students’ in-depth exploration of classroom experiments and to investigate their own ideas. The ability to explore individual interests independently further develops research skills and assists in students’ retention of classroom knowledge. The finished products are then presented to the public at various science education and outreach events throughout the community. Sharing self-motivated projects with the public not only enhances public knowledge, understanding, and interest, but also develops valuable communication skills in the students. A self-developed introductory research guidebook helps younger club members find a mentor in the astronomy or physics departments and begin working in a research group. Senior undergraduate students also facilitate a panel each semester to discuss their experiences in acquiring and maintaining an undergraduate research position.

Defining products for a new health technology assessment agency in Madrid, Spain: a survey of decision makers.

PubMed

Andradas, Elena; Blasco, Juan-Antonio; Valentín, Beatriz; López-Pedraza, María-José; Gracia, Francisco-Javier

2008-01-01

The aim of this study was to explore the needs and requirements of decision makers in our regional healthcare system for health technology assessment (HTA) products to support portfolio development planning for a new HTA agency in Madrid, Spain. A Delphi study was conducted during 2003. Questionnaires were developed based on a review of products and services offered by other agency members of the International Network of Agencies for Health Technology Assessment, and included preference and prioritization questions to evaluate twenty-two different products and services. The initial Delphi panel involved eighty-seven experts from twenty-one public hospitals, eleven primary healthcare centers, six private hospitals, and eight departments of the Regional Ministry of Health of the Community of Madrid. The global participation rate was 83.9 percent. Ten of the twenty-two possible products were rated of high interest by more than 80 percent of respondents. Important differences in preferences and priorities were detected across different settings. Public hospitals and primary healthcare centers shared a more "micro" perspective, preferring classic technology-centered HTA products, whereas private hospitals and Ministry representatives demanded more "macro" products and services such as organizational model and information system assessments. The high participation rate supports the representativeness of the results for our regional context. The strategic development of an HTA portfolio based on decision makers' needs and requirements as identified in this type of exercise should help achieve a better impact on policy development and decision making.

Retrospective analysis of natural products provides insights for future discovery trends

PubMed Central

Pye, Cameron R.; Bertin, Matthew J.; Lokey, R. Scott; Gerwick, William H.

2017-01-01

Understanding of the capacity of the natural world to produce secondary metabolites is important to a broad range of fields, including drug discovery, ecology, biosynthesis, and chemical biology, among others. Both the absolute number and the rate of discovery of natural products have increased significantly in recent years. However, there is a perception and concern that the fundamental novelty of these discoveries is decreasing relative to previously known natural products. This study presents a quantitative examination of the field from the perspective of both number of compounds and compound novelty using a dataset of all published microbial and marine-derived natural products. This analysis aimed to explore a number of key questions, such as how the rate of discovery of new natural products has changed over the past decades, how the average natural product structural novelty has changed as a function of time, whether exploring novel taxonomic space affords an advantage in terms of novel compound discovery, and whether it is possible to estimate how close we are to having described all of the chemical space covered by natural products. Our analyses demonstrate that most natural products being published today bear structural similarity to previously published compounds, and that the range of scaffolds readily accessible from nature is limited. However, the analysis also shows that the field continues to discover appreciable numbers of natural products with no structural precedent. Together, these results suggest that the development of innovative discovery methods will continue to yield compounds with unique structural and biological properties. PMID:28461474

Editorial for Special Issue on Herbal Medicines and Natural Products.

PubMed

Zhou, Zhi-Wei; Zhou, Shu-Feng

2015-11-16

Herbal medicines and natural products have been the most productive source of drug development and there is a large line of evidence on the applications of herbal medicines and natural products for the management of body function and the treatment of aliments. The multiple bioactive components in herbal medicines and natural products can explain the multiple targets effect in their medical applications. The increasing usage of state-of-art computational, molecular biological, and analytical chemistry techniques will promote the exploration of the pharmacological effect of previously inaccessible sources of herbal medicines and natural products. Notably, with the increasing reports on the safety issues regarding the medical use of herbal medicines and natural products, the awareness of pharmacovigilance in herbal medicines and natural products needs to be strengthened. To prevent the adverse drug reactions related to herbal medicines and natural products, physicians need to be aware of potential risks and alert patients in the use of herbal medicines and natural products.

Regulation and Device Development: Tips for Optimizing Your Experience With the Food and Drug Administration.

PubMed

Brooks, Steven S

2017-06-01

Physician-inventors are in a unique position to identify unserved patient needs, and innovate solutions to clinical problems. These solutions may also have associated commercial opportunities. The logistics of developing these medical products, however, can seem a daunting task. One of the primary barriers in the United States is the regulatory process of the Food and Drug Administration (FDA). In this article, we will explore the risk-based approach used by the FDA which forms a framework to consider the regulatory pathway and the process to gain regulatory clearance or approval for medical devices. Inherent device properties and the procedural risk of the devices will determine the rigor with which they are scrutinized by FDA, and the evidentiary requirements to legally market them. Data and evidentiary development will vary depending on risk and regulatory precedent and may or may not require clinical data This regulatory paradigm will determine into which risk-based device class they fit, and whether they are regulated under the 510(k) or premarket approval application pathways. The FDA, although gatekeeper of the US market and tasked with determining which products are safe and effective, can be a powerful ally for product development. They have significant scientific and medical expertise, and mechanisms to both provide guidance, and also to consider novel approaches to product development and evidence development. Early interaction for routine and novel products alike can result in expedited and efficient development. This collaborative approach can be best practice to most expeditiously develop the next generation of products, getting them into the hands of US doctors and into the treatment of US patients. Copyright © 2017. Published by Elsevier Inc.

NASA's Solar System Treks: Online Portals for Planetary Mapping and Modeling

NASA Astrophysics Data System (ADS)

Day, B. H.; Law, E.

2017-12-01

NASA's Solar System Treks are a suite of web-based of lunar and planetary mapping and modeling portals providing interactive visualization and analysis tools enabling mission planners, planetary scientists, students, and the general public to access mapped lunar data products from past and current missions for the Moon, Mars, Vesta, and more. New portals for additional planetary bodies are being planned. This presentation will recap significant enhancements to these toolsets during the past year and look ahead to future features and releases. Moon Trek is a new portal replacing its predecessor, the Lunar Mapping and Modeling Portal (LMMP), that significantly upgrades and builds upon the capabilities of LMMP. It features greatly improved navigation, 3D visualization, fly-overs, performance, and reliability. Additional data products and tools continue to be added. These include both generalized products as well as polar data products specifically targeting potential sites for NASA's Resource Prospector mission as well as for missions being planned by NASA's international partners. The latest release of Mars Trek includes new tools and data products requested by NASA's Planetary Science Division to support site selection and analysis for Mars Human Landing Exploration Zone Sites. Also being given very high priority by NASA Headquarters is Mars Trek's use as a means to directly involve the public in upcoming missions, letting them explore the areas the agency is focusing upon, understand what makes these sites so fascinating, follow the selection process, and get caught up in the excitement of exploring Mars. Phobos Trek, the latest effort in the Solar System Treks suite, is being developed in coordination with the International Phobos/Deimos Landing Site Working Group, with landing site selection and analysis for JAXA's MMX mission as a primary driver.

Microalgae as sustainable renewable energy feedstock for biofuel production.

PubMed

Medipally, Srikanth Reddy; Yusoff, Fatimah Md; Banerjee, Sanjoy; Shariff, M

2015-01-01

The world energy crisis and increased greenhouse gas emissions have driven the search for alternative and environmentally friendly renewable energy sources. According to life cycle analysis, microalgae biofuel is identified as one of the major renewable energy sources for sustainable development, with potential to replace the fossil-based fuels. Microalgae biofuel was devoid of the major drawbacks associated with oil crops and lignocelluloses-based biofuels. Algae-based biofuels are technically and economically viable and cost competitive, require no additional lands, require minimal water use, and mitigate atmospheric CO2. However, commercial production of microalgae biodiesel is still not feasible due to the low biomass concentration and costly downstream processes. The viability of microalgae biodiesel production can be achieved by designing advanced photobioreactors, developing low cost technologies for biomass harvesting, drying, and oil extraction. Commercial production can also be accomplished by improving the genetic engineering strategies to control environmental stress conditions and by engineering metabolic pathways for high lipid production. In addition, new emerging technologies such as algal-bacterial interactions for enhancement of microalgae growth and lipid production are also explored. This review focuses mainly on the problems encountered in the commercial production of microalgae biofuels and the possible techniques to overcome these difficulties.

Microalgae as Sustainable Renewable Energy Feedstock for Biofuel Production

PubMed Central

Yusoff, Fatimah Md.; Shariff, M.

2015-01-01

The world energy crisis and increased greenhouse gas emissions have driven the search for alternative and environmentally friendly renewable energy sources. According to life cycle analysis, microalgae biofuel is identified as one of the major renewable energy sources for sustainable development, with potential to replace the fossil-based fuels. Microalgae biofuel was devoid of the major drawbacks associated with oil crops and lignocelluloses-based biofuels. Algae-based biofuels are technically and economically viable and cost competitive, require no additional lands, require minimal water use, and mitigate atmospheric CO2. However, commercial production of microalgae biodiesel is still not feasible due to the low biomass concentration and costly downstream processes. The viability of microalgae biodiesel production can be achieved by designing advanced photobioreactors, developing low cost technologies for biomass harvesting, drying, and oil extraction. Commercial production can also be accomplished by improving the genetic engineering strategies to control environmental stress conditions and by engineering metabolic pathways for high lipid production. In addition, new emerging technologies such as algal-bacterial interactions for enhancement of microalgae growth and lipid production are also explored. This review focuses mainly on the problems encountered in the commercial production of microalgae biofuels and the possible techniques to overcome these difficulties. PMID:25874216

Developing an Earth system Inverse model for the Earth's energy and water budgets.

NASA Astrophysics Data System (ADS)

Haines, K.; Thomas, C.; Liu, C.; Allan, R. P.; Carneiro, D. M.

2017-12-01

The CONCEPT-Heat project aims at developing a consistent energy budget for the Earth system in order to better understand and quantify global change. We advocate a variational "Earth system inverse" solution as the best methodology to bring the necessary expertise from different disciplines together. L'Ecuyer et al (2015) and Rodell et al (2015) first used a variational approach to adjust multiple satellite data products for air-sea-land vertical fluxes of heat and freshwater, achieving closed budgets on a regional and global scale. However their treatment of horizontal energy and water redistribution and its uncertainties was limited. Following the recent work of Liu et al (2015, 2017) which used atmospheric reanalysis convergences to derive a new total surface heat flux product from top of atmosphere fluxes, we have revisited the variational budget approach introducing a more extensive analysis of the role of horizontal transports of heat and freshwater, using multiple atmospheric and ocean reanalysis products. We find considerable improvements in fluxes in regions such as the North Atlantic and Arctic, for example requiring higher atmospheric heat and water convergences over the Arctic than given by ERA-Interim, thereby allowing lower and more realistic oceanic transports. We explore using the variational uncertainty analysis to produce lower resolution corrections to higher resolution flux products and test these against in situ flux data. We also explore the covariance errors implied between component fluxes that are imposed by the regional budget constraints. Finally we propose this as a valuable methodology for developing consistent observational constraints on the energy and water budgets in climate models. We take a first look at the same regional budget quantities in CMIP5 models and consider the implications of the differences for the processes and biases active in the models. Many further avenues of investigation are possible focused on better valuing the uncertainties in observational flux products and setting requirement targets for future observation programs.

Human Research Program Exploration Medical Capability

NASA Technical Reports Server (NTRS)

Barsten, Kristina

2010-01-01

NASA s Human Research Program (HRP) conducts and coordinates research projects that provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration. The Program is divided into 6 major elements, which a) Provide the Program s knowledge and capabilities to conduct research, addressing the human health and performance risks. b) Advance the readiness levels of technology and countermeasures to the point of transfer to the customer programs and organizations. The National Space Biomedical Research Institute (NSBRI) is a partner with the HRP in developing a successful research program. 3

Environmental Management Competitive Pressure Effect on SME Environmental Innovation Activities: A Green Supply Chain Perspective

NASA Astrophysics Data System (ADS)

Rashid, A. A.; Sidek, A. A.; Suffian, S. A.; Daud, M. R. C.

2018-01-01

The idea of assimilating green supply chain is to integrate and establish environmental management into the supply chain practices. The study aims to explore how environmental management competitive pressure influences a SME company in Malaysia to incorporate green supply chain integration, which is an efficient platform to develop environmental innovation. This study further advances green supply chain management research in Malaysia by using the method of quantitative analysis to analyze the model developed which data will be collected based on a sample of SMEs in Malaysia in manufacturing sector. The model developed in this study illustrates how environmental management competitive pressure from main competitors affects three fundamental dimensions of green supply chain integration. The research findings suggest that environmental management competitive pressure is a vital driving force for a SME company to incorporate internal and external collaboration in developing green product innovation. From the analysis conducted, the study strongly demonstrated that the best way for a company to counteract competitor’s environmental management success is to first implement strong internal green product development process then move to incorporate external environmental management innovation between their suppliers and customers. The findings also show that internal integration of green product innovation fully mediates the relationship of environmental management competitive pressure and the external integration of green product innovation.

Ozone impacts of natural gas development in the Haynesville Shale.

PubMed

Kemball-Cook, Susan; Bar-Ilan, Amnon; Grant, John; Parker, Lynsey; Jung, Jaegun; Santamaria, Wilson; Mathews, Jim; Yarwood, Greg

2010-12-15

The Haynesville Shale is a subsurface rock formation located beneath the Northeast Texas/Northwest Louisiana border near Shreveport. This formation is estimated to contain very large recoverable reserves of natural gas, and during the two years since the drilling of the first highly productive wells in 2008, has been the focus of intensive leasing and exploration activity. The development of natural gas resources within the Haynesville Shale is likely to be economically important but may also generate significant emissions of ozone precursors. Using well production data from state regulatory agencies and a review of the available literature, projections of future year Haynesville Shale natural gas production were derived for 2009-2020 for three scenarios corresponding to limited, moderate, and aggressive development. These production estimates were then used to develop an emission inventory for each of the three scenarios. Photochemical modeling of the year 2012 showed increases in 2012 8-h ozone design values of up to 5 ppb within Northeast Texas and Northwest Louisiana resulting from development in the Haynesville Shale. Ozone increases due to Haynesville Shale emissions can affect regions outside Northeast Texas and Northwest Louisiana due to ozone transport. This study evaluates only near-term ozone impacts, but the emission inventory projections indicate that Haynesville emissions may be expected to increase through 2020.

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development

PubMed Central

Tomar, Dheeraj S.; Kumar, Sandeep; Singh, Satish K.; Goswami, Sumit; Li, Li

2016-01-01

ABSTRACT Effective translation of breakthrough discoveries into innovative products in the clinic requires proactive mitigation or elimination of several drug development challenges. These challenges can vary depending upon the type of drug molecule. In the case of therapeutic antibody candidates, a commonly encountered challenge is high viscosity of the concentrated antibody solutions. Concentration-dependent viscosity behaviors of mAbs and other biologic entities may depend on pairwise and higher-order intermolecular interactions, non-native aggregation, and concentration-dependent fluctuations of various antibody regions. This article reviews our current understanding of molecular origins of viscosity behaviors of antibody solutions. We discuss general strategies and guidelines to select low viscosity candidates or optimize lead candidates for lower viscosity at early drug discovery stages. Moreover, strategies for formulation optimization and excipient design are also presented for candidates already in advanced product development stages. Potential future directions for research in this field are also explored. PMID:26736022

Reward and uncertainty in exploration programs

NASA Technical Reports Server (NTRS)

Kaufman, G. M.; Bradley, P. G.

1971-01-01

A set of variables which are crucial to the economic outcome of petroleum exploration are discussed. These are treated as random variables; the values they assume indicate the number of successes that occur in a drilling program and determine, for a particular discovery, the unit production cost and net economic return if that reservoir is developed. In specifying the joint probability law for those variables, extreme and probably unrealistic assumptions are made. In particular, the different random variables are assumed to be independently distributed. Using postulated probability functions and specified parameters, values are generated for selected random variables, such as reservoir size. From this set of values the economic magnitudes of interest, net return and unit production cost are computed. This constitutes a single trial, and the procedure is repeated many times. The resulting histograms approximate the probability density functions of the variables which describe the economic outcomes of an exploratory drilling program.

Coproduction of healthcare service

PubMed Central

Batalden, Maren; Batalden, Paul; Margolis, Peter; Seid, Michael; Armstrong, Gail; Opipari-Arrigan, Lisa; Hartung, Hans

2016-01-01

Efforts to ensure effective participation of patients in healthcare are called by many names—patient centredness, patient engagement, patient experience. Improvement initiatives in this domain often resemble the efforts of manufacturers to engage consumers in designing and marketing products. Services, however, are fundamentally different than products; unlike goods, services are always ‘coproduced’. Failure to recognise this unique character of a service and its implications may limit our success in partnering with patients to improve health care. We trace a partial history of the coproduction concept, present a model of healthcare service coproduction and explore its application as a design principle in three healthcare service delivery innovations. We use the principle to examine the roles, relationships and aims of this interdependent work. We explore the principle's implications and challenges for health professional development, for service delivery system design and for understanding and measuring benefit in healthcare services. PMID:26376674

Using Authentic Science in the Classroom: NASA's Coordinated Efforts to Enhance STEM Education

NASA Astrophysics Data System (ADS)

Lawton, B.; Schwerin, T.; Low, R.

2015-11-01

A key NASA education goal is to attract and retain students in science, technology engineering, and mathematics (STEM) disciplines. When teachers engage students in the examination of authentic data derived from NASA satellite missions, they simultaneously build 21st century technology skills as well as core content knowledge about the Earth and space. In this session, we highlight coordinated efforts by NASA Science Mission Directorate (SMD) Education and Public Outreach (EPO) programs to enhance educator accessibility to data resources, distribute state-of -the-art data tools and expand pathways for educators to find and use data resources. The group discussion explores how NASA SMD EPO efforts can further improve teacher access to authentic NASA data, identifies the types of tools and lessons most requested by the community, and explores how communication and collaboration between product developers and classroom educators using data tools and products can be enhanced.

Nanofiltration/reverse osmosis for treatment of coproduced waters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mondal, S.; Hsiao, C.L.; Wickramasinghe, S.R.

2008-07-15

Current high oil and gas prices have lead to renewed interest in exploration of nonconventional energy sources such as coal bed methane, tar sand, and oil shale. However oil and gas production from these nonconventional sources has lead to the coproduction of large quantities of produced water. While produced water is a waste product from oil and gas exploration it is a very valuable natural resource in the arid Western United States. Thus treated produced water could be a valuable new source of water. Commercially available nanofiltration and low pressure reverse osmosis membranes have been used to treat three producedmore » waters. The results obtained here indicate that the permeate could be put to beneficial uses such as crop and livestock watering. However minimizing membrane fouling will be essential for the development of a practical process. Field Emission Scanning Electron Microscopy imaging may be used to observe membrane fouling.« less

Microgravity

NASA Image and Video Library

2004-04-15

The manipulation of organic materials--cells, tissues, and even living organisms--offers many exciting possibilities for the future from organic computers to improved aquaculture. Commercial researchers are using the microgravity environment to produce large near perfect protein crystals Research on insulin has yielded crystals that far surpass the quality of insulin crystals grown on the ground. Using these crystals industry partners are working to develop new and improved treatments for diabetes. Other researchers are exploring the possibility of producing antibiotics using plant cell cultures which could lead to both orbital production and the improvement of ground-based antibiotic production.

Final Environmental Impact Statement for the Mineral Resource Management Plan. Potential Exploration, Development, and Production of Oil and Gas Resources; Vandenberg Air Force Base, California

DTIC Science & Technology

1987-12-01

this acreage represents good hydrocarbon potential). As a matter of fact, it is Newhall Resources’ intention to actively market its acreage for leasing...gas market conditions were such that they exceeded the assumed "most likely" volumes of oil production over the next 40 years identified in Table 2-1 of...years aqo and the bottom floor housed Perozzi Hardware until it went out of business this year, 1986. Appropriately, there is an antique market there

Insulin

NASA Technical Reports Server (NTRS)

2004-01-01

The manipulation of organic materials--cells, tissues, and even living organisms--offers many exciting possibilities for the future from organic computers to improved aquaculture. Commercial researchers are using the microgravity environment to produce large near perfect protein crystals Research on insulin has yielded crystals that far surpass the quality of insulin crystals grown on the ground. Using these crystals industry partners are working to develop new and improved treatments for diabetes. Other researchers are exploring the possibility of producing antibiotics using plant cell cultures which could lead to both orbital production and the improvement of ground-based antibiotic production.

News: Synthetic biology leading to specialty chemicals ...

EPA Pesticide Factsheets

Synthetic biology can combine the disciplines of biology, engineering, and chemistry productively to form molecules of great scientific and commercial value. Recent advances in the new field are explored for their connection to new tools that have been used to elucidate production pathways to a wide variety of chemicals generated by microorganisms. The selection and enhancement of microbiological strains through the practice of strain engineering enables targets of design, construction, and optimization. This news column aspires to cover recent literature relating to the development and understanding of clean technology.

Quality engineering as a profession.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kolb, Rachel R.; Hoover, Marcey L.

Over the course of time, the profession of quality engineering has witnessed significant change, from its original emphasis on quality control and inspection to a more contemporary focus on upholding quality processes throughout the organization and its product realization activities. This paper describes the profession of quality engineering, exploring how todays quality engineers and quality professionals are certified individuals committed to upholding quality processes and principles while working with different dimensions of product development. It also discusses the future of the quality engineering profession and the future of the quality movement as a whole.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This case history discusses the exploration methods used at the Momotombo Geothermal Field in western Nicaragua, and evaluates their contributions to the development of the geothermal field models. Subsequent reservoir engineering has not been synthesized or evaluated. A geothermal exploration program was started in Nicaragua in 1966 to discover and delineate potential geothermal reservoirs in western Nicaragua. Exploration began at the Momotombo field in 1970 using geological, geochemical, and geophysical methods. A regional study of thermal manifestations was undertaken and the area on the southern flank of Volcan Momotombo was chosen for more detailed investigation. Subsequent exploration by various consultantsmore » produced a number of geotechnical reports on the geology, geophysics, and geochemistry of the field as well as describing production well drilling. Geological investigations at Momotombo included photogeology, field mapping, binocular microscope examination of cuttings, and drillhole correlations. Among the geophysical techniques used to investigate the field sub-structure were: Schlumberger and electromagnetic soundings, dipole mapping and audio-magnetotelluric surveys, gravity and magnetic measurements, frequency domain soundings, self-potential surveys, and subsurface temperature determinations. The geochemical program analyzed the thermal fluids of the surface and in the wells. This report presents the description and results of exploration methods used during the investigative stages of the Momotombo Geothermal Field. A conceptual model of the geothermal field was drawn from the information available at each exploration phase. The exploration methods have been evaluated with respect to their contributions to the understanding of the field and their utilization in planning further development. Our principal finding is that data developed at each stage were not sufficiently integrated to guide further work at the field, causing inefficient use of resources.« less

Two-Phase Flow Technology Developed and Demonstrated for the Vision for Exploration

NASA Technical Reports Server (NTRS)

Sankovic, John M.; McQuillen, John B.; Lekan, Jack F.

2005-01-01

NASA s vision for exploration will once again expand the bounds of human presence in the universe with planned missions to the Moon and Mars. To attain the numerous goals of this vision, NASA will need to develop technologies in several areas, including advanced power-generation and thermal-control systems for spacecraft and life support. The development of these systems will have to be demonstrated prior to implementation to ensure safe and reliable operation in reduced-gravity environments. The Two-Phase Flow Facility (T(PHI) FFy) Project will provide the path to these enabling technologies for critical multiphase fluid products. The safety and reliability of future systems will be enhanced by addressing focused microgravity fluid physics issues associated with flow boiling, condensation, phase separation, and system stability, all of which are essential to exploration technology. The project--a multiyear effort initiated in 2004--will include concept development, normal-gravity testing (laboratories), reduced gravity aircraft flight campaigns (NASA s KC-135 and C-9 aircraft), space-flight experimentation (International Space Station), and model development. This project will be implemented by a team from the NASA Glenn Research Center, QSS Group, Inc., ZIN Technologies, Inc., and the Extramural Strategic Research Team composed of experts from academia.

MONTANA PALLADIUM RESEARCH INITIATIVE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peters, John; McCloskey, Jay; Douglas, Trevor

2012-05-09

Project Objective: The overarching objective of the Montana Palladium Research Initiative is to perform scientific research on the properties and uses of palladium in the context of the U.S. Department of Energy's Hydrogen, Fuel Cells and Infrastructure Technologies Program. The purpose of the research will be to explore possible palladium as an alternative to platinum in hydrogen-economy applications. To achieve this objective, the Initiatives activities will focus on several cutting-edge research approaches across a range of disciplines, including metallurgy, biomimetics, instrumentation development, and systems analysis. Background: Platinum-group elements (PGEs) play significant roles in processing hydrogen, an element that shows highmore » potential to address this need in the U.S. and the world for inexpensive, reliable, clean energy. Platinum, however, is a very expensive component of current and planned systems, so less-expensive alternatives that have similar physical properties are being sought. To this end, several tasks have been defined under the rubric of the Montana Palladium Research Iniative. This broad swath of activities will allow progress on several fronts. The membrane-related activities of Task 1 employs state-of-the-art and leading-edge technologies to develop new, ceramic-substrate metallic membranes for the production of high-purity hydrogen, and develop techniques for the production of thin, defect-free platinum group element catalytic membranes for energy production and pollution control. The biomimetic work in Task 2 explores the use of substrate-attached hydrogen-producing enzymes and the encapsulation of palladium in virion-based protein coats to determine their utility for distributed hydrogen production. Task 3 work involves developing laser-induced breakdown spectroscopy (LIBS) as a real-time, in situ diagnostic technique to characterize PGEs nanoparticles for process monitoring and control. The systems engineering work in task 4 will determine how fuel cells taken as systems behave over periods of time that should show how their reformers and other subsystems deteriorate with time.« less

Mineral resource management of the Outer Continental Shelf : leasing procedures, evaluation of resources, and supervision of production operations on leased lands of the Outer Continental Shelf

USGS Publications Warehouse

Adams, Maurice V.; John, C.B.; Kelly, R.F.; LaPointe, A.E.; Meurer, R.W.

1975-01-01

An important function of the Geological Survey is the evaluation and management of the mineral resources of the Outer Continental Shelf, particularly with respect to oil and gas, salt, and sulfur. Production of oil and gas from the Outer Continental Shelf of the United States has increased substantially over the past 20 years and represents an increasing percentage of total United States production. As discovery of major onshore production of oil and gas has become more difficult, the search has moved into the surrounding waters where submerged sedimentary formations are conducive to the accumulation of oil and gas. Increased energy demands of recent years have accelerated the pace of offshore operations with a corresponding improvement in technology as exploration and development have proceeded farther from shore and into deeper water. While improved technology and enforcement of more stringent regulations have made offshore operations safer, it is unrealistic to believe that completely accident-free operations can ever be achieved. Only slightly more than six percent of the world's continental terrace is adjacent to the United States, but less than one percent has been explored for oil and gas. Since the lead time for the development of offshore oil and gas resources can be as much as a decade, they do not provide an immediate energy supply but should be viewed in the light of a near-term source with a potential of becoming a medium-range source of supply pending the development of alternative energy sources. Revenues from the Outer Continental Shelf are deposited to the general fund of the United States Treasury. A major portion of these funds is allocated to the Land and Water Conservation Fund, the largest Federal grant-in-aid program of assistance to States, counties, and cities for the acquisition and development of public parks, open space, and recreation lands and water.

The chlorinated AHR ligand 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) promotes reactive oxygen species (ROS) production during embryonic development in the killifish (Fundulus heteroclitus)

USGS Publications Warehouse

Arzuaga, Xabier; Wassenberg, Deena; Giulio, Richard D.; Elskus, Adria

2006-01-01

Exposure to dioxin-like chemicals that activate the aryl hydrocarbon receptor (AHR) can result in increased cellular and tissue production of reactive oxygen species (ROS). Little is known of these effects during early fish development. We used the fish model, Fundulus heteroclitus, to determine if the AHR ligand and pro-oxidant 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) can increase ROS production during killifish development, and to test a novel method for measuring ROS non-invasively in a living organism. The superoxide-sensitive fluorescent dye, dihydroethidium (DHE), was used to detect in ovo ROS production microscopically in developing killifish exposed to PCB126 or vehicle. Both in ovo CYP1A activity (ethoxyresorufin-o-deethylase, EROD) and in ovo ROS were induced by PCB126. In ovo CYP1A activity was inducible by PCB126 concentrations as low as 0.003 nM, with maximal induction occurring at 0.3 nM PCB126. These PCB126 concentrations also significantly increased in ovo ROS production in embryonic liver, ROS being detectable as early as 5 days post-fertilization. These data demonstrate that the pro-oxidant and CYP1A inducer, PCB126, increases both CYP1A activity and ROS production in developing killifish embryos. The superoxide detection assay (SoDA) described in this paper provides a semi-quantitative, easily measured, early indicator of altered ROS production that can be used in conjunction with simultaneous in ovo measurements of CYP1A activity and embryo development to explore functional relationships among biochemical, physiological and developmental responses to AHR ligands.

Ambiguous Pronoun Use in Narratives of Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Novogrodsky, Rama; Edelson, Lisa R.

2016-01-01

This study explored pronoun production and general syntactic abilities in story retelling and story generation among children with autism spectrum disorders (ASD). Twenty-four children diagnosed with ASD, ages 6;1-14;3 and 17 typically-developing (TD) children ages 5;11-14;4 participated in the study. The linguistic measures for general syntax…

Learning to Ask Naive Questions with IT Product Design Students

ERIC Educational Resources Information Center

Gunn, Wendy

2008-01-01

What does it mean to use, or do, theory in the scholarship of teaching and learning? The article approaches the question by considering the role of design anthropology in developing studio-based engineering programmes. Central to my discussion within situated contexts of learning is the idea of practice-based exploration conceived as a way of…

76 FR 60856 - Information Collection Activities; Plans and Information; Submitted for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... affect a protected species. The Independent Offices Appropriations Act (31 U.S.C. 9701), the Omnibus Appropriations Bill (Pub. L. 104-133, 110 Stat. 1321, April 26, 1996), and OMB Circular A-25, authorize Federal... and gas or sulphur leases to submit exploration plans (EPs) and development and production plans (DPPs...

Career Exploration in Agribusiness, Renewable Natural Resources, and Environmental Protection: A Curriculum Guide for Grades 7-9.

ERIC Educational Resources Information Center

Lawson, Dorothy; And Others

This guide contains eight learning modules which are designed as samples which fuse the career development concepts, subject matter, and occupational information into learning activities using occupations as the nucleus. There is one module for each of the eight occupational areas: agricultural equipment and mechanics, agricultural products (food…

Food or Fuel: New Competition for the World's Cropland. Worldwatch Paper 35.

ERIC Educational Resources Information Center

Brown, Lester R.

The paper explores how continuously expanding world demand for food, feed, and fuel is generating pressure to restructure agricultural land use. In addition, problems related to transfer of agricultural crop land to energy crops are discussed. The technology of energy crops has developed to the point where large-scale commercial production of…

Supporting Authors in the Development of Task-Based Learning in Serious Virtual Worlds

ERIC Educational Resources Information Center

Bellotti, Francesco; Berta, Riccardo; De Gloria, Alessandro; Primavera, Ludovica

2010-01-01

Serious virtual worlds (SVWs) represent a great opportunity for learning and should embed a lot of high-quality contextualised information so that the player can take the most from his or her exploration of the environment. This requires defining new methodologies and tools for effective production. We have investigated this issue in implementing…

30 CFR 250.303 - Facilities described in a new or revised Exploration Plan or Development and Production Plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... further air quality review, the lessee shall use the highest annual-total amount of emissions from the... MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER... quality of an onshore area. To make these decisions, the Regional Supervisor shall consider the distance...

Publishing for Pre-Tertiary Education in Ghana: The 2002 Textbook Policy in Retrospect

ERIC Educational Resources Information Center

Opoku-Amankwa, Kwasi; Brew-Hammond, Aba; Mahama, Anatu Kande

2015-01-01

This paper assesses the performance of the "National Textbook Development and Distribution Policy for Pre-Tertiary Education" of 2002. It examines the policy in theory and in practice by exploring the extent to which the liberalisation of the textbook trade has helped to improve on textbook procurement, production and distribution,…

Exploring the Effects of Teachers' and Learners' Conflicting Beliefs on the Provision of Corrective Feedback during Undisturbed Classroom Interactions

ERIC Educational Resources Information Center

Garcia-Ponce, Edgar Emmanuell; Mora-Pablo, Irasema

2017-01-01

Extensive research literature suggests that corrective feedback (CF), when effective, has a beneficial impact on the development of learners' interlanguage. This is because CF provides learners with language data concerning the correctness of their utterances and thus pushes their oral production towards greater clarity, accuracy and…

30 CFR 250.303 - Facilities described in a new or revised Exploration Plan or Development and Production Plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... exempt from further air quality review, the lessee shall use the highest annual-total amount of emissions... ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND... potential to significantly affect the air quality of an onshore area. To make these decisions, the Regional...

Bilingualism Aids Conflict Resolution: Evidence from the ANT Task

ERIC Educational Resources Information Center

Costa, Albert; Hernandez, Mirea; Sebastian-Galles, Nuria

2008-01-01

The need of bilinguals to continuously control two languages during speech production may exert general effects on their attentional networks. To explore this issue we compared the performance of bilinguals and monolinguals in the attentional network task (ANT) developed by Fan et al. [Fan, J., McCandliss, B.D. Sommer, T., Raz, A., Posner, M.I.…

Technical Knowledge and Skills Development in the Informal Sector in Kenya: The Case of Custom Tailors

ERIC Educational Resources Information Center

Apunda, Edwinah Amondi; de Klerk, Helena M.; Ogina, Teresa

2017-01-01

Custom tailors working in the informal sector in Nairobi, Kenya, mainly acquire technical skills through undertaking traditional apprenticeships (TAs). However, most of these tailors are semi-skilled, produce low-quality products and are often poorer than their formally trained counterparts. This qualitative case study explores the aspects of…

Opportunities to Write: An Exploration of Student Writing during Language Arts Lessons in Norwegian Lower Secondary Classrooms

ERIC Educational Resources Information Center

Blikstad-Balas, Marte; Roe, Astrid; Klette, Kirsti

2018-01-01

Research suggests that student development as writers requires a supportive environment in which they receive sustained opportunities to write. However, writing researchers in general know relatively little about the actual writing opportunities embedded in students' language arts lessons and how students' production of texts in class is framed.…

Legal History Meets the Honors Program

ERIC Educational Resources Information Center

Bennett, Robert B., Jr.

2009-01-01

In this article, the author discusses the "Law and Culture" course that he developed to teach in the Butler University Honors Program. The course looks at some landmark periods or events in legal history and explores how those events were the product of their culture, and how they affected their culture. Among the events or periods that the author…

The emergy of metabolism in the same ecosystem (maize) under different environmental conditions

Treesearch

Xiajie Zhai; Huan Zhao; Lizhu Guo; Deborah M. Finch; Ding Huang; Kesi Liu; Shiming Tang; Yuejuan Yang; Jianxin Guo; Jiahuan Li; Shu Xie; Kun Wang

2018-01-01

Ecosystem sustainability is the basis for life, economic and social sustainability. The energy metabolism of an ecosystem has long been a focus area in the scientific community because it determines the productivity, sustainability and development of ecosystem. This study applied emergy analysis to explore the metabolism of maize ecosystems under different...