Changes in the Influence of Alcohol-Paired Stimuli on Alcohol Seeking across Extended Training

PubMed Central

Corbit, Laura H.; Janak, Patricia H.

2016-01-01

Previous work has demonstrated that goal-directed control of alcohol-seeking and other drug-related behaviors is reduced following extended self-administration and drug exposure. Here, we examined how the magnitude of stimulus influences on responding changes across similar training and drug exposure. Rats self-administered alcohol or sucrose for 2 or 8 weeks. Previous work has shown that 8 weeks, but not 2 weeks of self-administration produces habitual alcohol seeking. Next, all animals received equivalent Pavlovian conditioning sessions where a discrete stimulus predicted the delivery of alcohol or sucrose. Finally, the impact of the stimuli on ongoing instrumental responding was examined in a Pavlovian–instrumental transfer (PIT) test. While a significant PIT effect was observed following 2 weeks of either alcohol or sucrose self-administration, the magnitude of this effect was greater following 8 weeks of training. The specificity of the PIT effect appeared unchanged by extended training. While it is well established that evaluation of the outcome of responding contributes less to behavioral control following extended training and/or drug exposure, our data indicate that reward–predictive stimuli have a stronger contribution to responding after extended training. Together, these findings provide insight into the factors that control behavior after extended drug use, which will be important for developing effective methods for controlling and ideally reducing these behaviors. PMID:27777560

High body mass index is associated with impaired cognitive control.

PubMed

Sellaro, Roberta; Colzato, Lorenza S

2017-06-01

The prevalence of weight problems is increasing worldwide. There is growing evidence that high body mass index (BMI) is associated with frontal lobe dysfunction and cognitive deficits concerning mental flexibility and inhibitory control efficiency. The present study aims at replicating and extending these observations. We compared cognitive control performance of normal weight (BMI < 25) and overweight (BMI ≥ 25) university students on a task tapping either inhibitory control (Experiment 1) or interference control (Experiment 2). Experiment 1 replicated previous findings that found less efficient inhibitory control in overweight individuals. Experiment 2 complemented these findings by showing that cognitive control impairments associated with high BMI also extend to the ability to resolve stimulus-induced response conflict and to engage in conflict-driven control adaptation. The present results are consistent with and extend previous literature showing that high BMI in young, otherwise healthy individuals is associated with less efficient cognitive control functioning. Copyright © 2017 Elsevier Ltd. All rights reserved.

Distribution of fine-scale mantle heterogeneity from observations of Pdiff coda

USGS Publications Warehouse

Earle, P.S.; Shearer, P.M.

2001-01-01

We present stacked record sections of Global Seismic Network data that image the average amplitude and polarization of the high-frequency Pdiff coda and investigate their implications on the depth extent of fine-scale (~10 km) mantle heterogeneity. The extended 1-Hz coda lasts for at least 150 sec and is observed to a distance of 130??. The coda's polarization angle is about the same as the main Pdiff arrival (4.4 sec/deg) and is nearly constant with time. Previous studies show that multiple scattering from heterogeneity restricted to the lowermost mantle generates an extended Pdiff coda with a constant polarization. Here we present an alternative model that satisfies our Pdiff observations. The model consists of single scattering from weak (~1%) fine-scale (~2 km) structures distributed throughout the mantle. Although this model is nonunique, it demonstrates that Pdiff coda observations do not preclude the existence of scattering contributions from the entire mantle.

A multiscale strength model for tantalum over an extended range of strain rates

NASA Astrophysics Data System (ADS)

Barton, N. R.; Rhee, M.

2013-09-01

A strength model for tantalum is developed and exercised across a range of conditions relevant to various types of experimental observations. The model is based on previous multiscale modeling work combined with experimental observations. As such, the model's parameterization includes a hybrid of quantities that arise directly from predictive sub-scale physics models and quantities that are adjusted to align the model with experimental observations. Given current computing and experimental limitations, the response regions for sub-scale physics simulations and detailed experimental observations have been largely disjoint. In formulating the new model and presenting results here, attention is paid to integrated experimental observations that probe strength response at the elevated strain rates where a previous version of the model has generally been successful in predicting experimental data [Barton et al., J. Appl. Phys. 109(7), 073501 (2011)].

Activation of extended red emission photoluminescence in carbon solids by exposure to atomic hydrogen and UV radiation

NASA Technical Reports Server (NTRS)

Furton, Douglas G.; Witt, Adolf N.

1993-01-01

We report on new laboratory results which relate directly to the observation of strongly enhanced extended red emission (ERE) by interstellar dust in H2 photodissociation zones. The ERE has been attributed to photoluminescence by hydrogenated amorphous carbon (HAC). We are demonstrating that exposure to thermally dissociated atomic hydrogen will restore the photoluminescence efficiency of previously annealed HAC. Also, pure amorphous carbon (AC), not previously photoluminescent, can be induced to photoluminesce by exposure to atomic hydrogen. This conversion of AC into HAC is greatly enhanced by the presence of UV irradiation. The presence of dense, warm atomic hydrogen and a strong UV radiation field are characteristic environmental properties of H2 dissociation zones. Our results lend strong support to the HAC photoluminescence explanation for ERE.

An Analysis of Simulated Wet Deposition of Mercury from the North American Mercury Model Intercomparison Study

EPA Science Inventory

A previous intercomparison of atmospheric mercury models in North America has been extended to compare simulated and observed wet deposition of mercury. Three regional-scale atmospheric mercury models were tested; CMAQ, REMSAD and TEAM. These models were each employed using thr...

Evolution of Crater Glacier, Mount St. Helens, Washington, September 2006-November 2009

USGS Publications Warehouse

Walder, Joseph S.; Schilling, Steven P.; Sherrod, David R.; Vallance, James W.

2010-01-01

Lava-dome emplacement through a glacier was observed for the first time during the 2004-08 eruption of Mount St. Helens and documented using photography, photogrammetry, and geodetic measurements. Previously published reports present such documentation through September 2006; this report extends that documentation until November 2009.

NCI International EBV-Gastric Cancer Consortium

Cancer.gov

A collaboration among NCI and extramural investigators, established by DCEG in 2006, that utilizes data and biospecimens from completed and ongoing case series and observational studies of gastric cancer to replicate and extend findings from previous studies hindered by small numbers of EBV-positive cases, and to stimulate multidisciplinary research in this area.

Plasma observations near saturn: initial results from voyager 2.

PubMed

Bridge, H S; Bagenal, F; Belcher, J W; Lazarus, A J; McNutt, R L; Sullivan, J D; Gazis, P R; Hartle, R E; Ogilvie, K W; Scudder, J D; Sittler, E C; Eviatar, A; Siscoe, G L; Goertz, C K; Vasyliunas, V M

1982-01-29

Results of measurements of plasma electrons and poitive ions made during the Voyager 2 encounter with Saturn have been combined with measurements from Voyager 1 and Pioneer 11 to define more clearly the configuration of plasma in the Saturnian magnetosphere. The general morphology is well represented by four regions: (i) the shocked solar wind plasma in the magnetosheath, observed between about 30 and 22 Saturn radii (RS) near the noon meridian; (ii) a variable density region between approximately 17 RS and the magnetopause; (iii) an extended thick plasma sheet between approximately 17 and approximately 7 RS symmetrical with respect to Saturn's equatorial plane and rotation axis; and (iv) an inner plasma torus that probably originates from local sources and extends inward from L approximately 7 to less than L approximately 2.7 (L is the magnetic shell parameter). In general, the heavy ions, probably O(+), are more closely confined to the equatorial plane than H(+), so that the ratio of heavy to light ions varies along the trajectory according to the distance of the spacecraft from the equatorial plane. The general configuration of the plasma sheet at Saturn found by Voyager 1 is confirmed, with some notable differences and additions. The "extended plasma sheet," observed between L approximately 7 and L approximately 15 by Voyager 1 is considerably thicker as observed by Voyager 2. Inward of L approximately 4, the plasma sheet collapses to a thin region about the equatorial plane. At the ring plane crossing, L approximately 2.7, the observations are consistent with a density of O(+) of approximately 100 per cubic centimeter, with a temperature of approximately 10 electron volts. The location of the bow shock and magnetopause crossings were consistent with those previously observed. The entire magnetosphere was larger during the outbound passage of Voyager 2 than had been previously observed; however, a magnetosphere of this size or larger is expected approximately 3 percent of the time.

GRB 080503: IMPLICATIONS OF A NAKED SHORT GAMMA-RAY BURST DOMINATED BY EXTENDED EMISSION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perley, D. A.; Metzger, B. D.; Butler, N. R.

We report on observations of GRB 080503, a short gamma-ray burst (GRB) with very bright extended emission (about 30 times the gamma-ray fluence of the initial spike) in conjunction with a thorough comparison to other short Swift events. In spite of the prompt-emission brightness, however, the optical counterpart is extraordinarily faint, never exceeding 25 mag in deep observations starting at {approx}1 hr after the Burst Alert Telescope (BAT) trigger. The optical brightness peaks at {approx}1 day and then falls sharply in a manner similar to the predictions of Li and Paczynski (1998) for supernova-like emission following compact binary mergers. However,more » a shallow spectral index and similar evolution in X-rays inferred from Chandra observations are more consistent with an afterglow interpretation. The extreme faintness of this probable afterglow relative to the bright gamma-ray emission argues for a very low density medium surrounding the burst (a 'naked' GRB), consistent with the lack of a coincident host galaxy down to 28.5 mag in deep Hubble Space Telescope imaging. The late optical and X-ray peak could be explained by a slightly off-axis jet or by a refreshed shock. Our observations reinforce the notion that short GRBs generally occur outside regions of active star formation, but demonstrate that in some cases the luminosity of the extended prompt emission can greatly exceed that of the short spike, which may constrain theoretical interpretation of this class of events. This extended emission is not the onset of an afterglow, and its relative brightness is probably either a viewing-angle effect or intrinsic to the central engine itself. Because most previous BAT short bursts without observed extended emission are too faint for this signature to have been detectable even if it were present at typical level, conclusions based solely on the observed presence or absence of extended emission in the existing Swift sample are premature.« less

Hard X-ray observations of the region from the galactic center to Centaurus

NASA Technical Reports Server (NTRS)

Guo, D. D.; Webber, W. R.; Damle, S. V.

1974-01-01

A balloon flight from Parana, Argentina, was conducted to observe emissions from discrete or extended sources in the southern sky. The sources observed include GX 304-1, Nor X-2, GX 340+0, GX 354-5, a possibly composite source near the galactic center, and the nova-like source (2U1543-47) in the Lupus-Norma region which has been reported previously only in satellite observations. Data concerning the possibility of line emission near 0.5 MeV from different regions of the southern sky are also presented.

Early warning signal for interior crises in excitable systems.

PubMed

Karnatak, Rajat; Kantz, Holger; Bialonski, Stephan

2017-10-01

The ability to reliably predict critical transitions in dynamical systems is a long-standing goal of diverse scientific communities. Previous work focused on early warning signals related to local bifurcations (critical slowing down) and nonbifurcation-type transitions. We extend this toolbox and report on a characteristic scaling behavior (critical attractor growth) which is indicative of an impending global bifurcation, an interior crisis in excitable systems. We demonstrate our early warning signal in a conceptual climate model as well as in a model of coupled neurons known to exhibit extreme events. We observed critical attractor growth prior to interior crises of chaotic as well as strange-nonchaotic attractors. These observations promise to extend the classes of transitions that can be predicted via early warning signals.

Pressure-enhanced ortho-para conversion in solid hydrogen up to 58 GPa

PubMed Central

Eggert, Jon H.; Karmon, Eran; Hemley, Russell J.; Mao, Ho-kwang; Goncharov, Alexander F.

1999-01-01

We measured the ortho-para conversion rate in solid hydrogen by using Raman scattering in a diamond-anvil cell, extending previous measurements by a factor of 60 in pressure. We confirm previous experiments that suggested a decrease in the conversion rate above about 0.5 GPa. We observe a distinct minimum at 3 GPa followed by a drastic increase in the conversion rate to our maximum pressure of 58 GPa. This pressure enhancement of conversion is not predicted by previous theoretical treatments and must be due to a new conversion pathway. PMID:10535910

XMM-Newton observations of NGC 3268 in the Antlia Galaxy Cluster: characterization of a hidden group of galaxies at z ≈ 0.41

NASA Astrophysics Data System (ADS)

Gargiulo, I. D.; García, F.; Combi, J. A.; Caso, J. P.; Bassino, L. P.

2018-05-01

We report on a detailed X-ray study of the extended emission of the intracluster medium (ICM) around NGC 3268, in the Antlia cluster of galaxies, together with a characterization of an extended source in the field, namely a background cluster of galaxies at z ≈ 0.41, which was previously accounted as an X-ray point source. The spectral properties of the extended emission of the gas present in Antlia were studied using data from the XMM-Newton satellite complemented with optical images of CTIO-Blanco telescope, to attain for associations of the optical sources with the X-ray emission. The XMM-Newton observations show that the intracluster gas is concentrated in a region centred in one of the main galaxies of the cluster, NGC 3268. By means of a spatially-resolved spectral analysis we derived the abundances of the ICM plasma. We found a wall-like feature in the northeast direction where the gas is characterized by a lower temperature with respect to the rest of the ICM. Furthermore, using combined optical observations we inferred the presence of an elliptical galaxy in the centre of the extended X-ray source considered as a background cluster, which favours this interpretation.

A Chandra Observation of the Ultraluminous Infrared Galaxy IRAS 19254-7245 (THE SUPERANTENNAE): X-Ray Emission From the Compton-Thick Active Galactic Nucleus and the Diffuse Starburst

NASA Technical Reports Server (NTRS)

Jia, Jianjun; Ptak, Andrew Francis; Heckman, Timothy M.; Braito, Valantina; Reeves, James

2012-01-01

We present a Chandra observation of IRAS 19254-7245, a nearby ultraluminous infrared galaxy also known as the Superantennae. The high spatial resolution of Chandra allows us to disentangle for the first time the diffuse starburst (SB) emission from the embedded Compton-thick active galactic nucleus (AGN) in the southern nucleus. No AGN activity is detected in the northern nucleus. The 2-10 keV spectrum of the AGN emission is fitted by a flat power law (G = 1.3) and an He-like Fe Ka line with equivalent width 1.5 keV, consistent with previous observations. The Fe Ka line profile could be resolved as a blend of a neutral 6.4 keV line and an ionized 6.7 keV (He-like) or 6.9 keV (H-like) line. Variability of the neutral line is detected compared with the previous XMM-Newton and Suzaku observations, demonstrating the compact size of the iron line emission. The spectrum of the galaxy-scale extended emission excluding the AGN and other bright point sources is fitted with a thermal component with a best-fit kT of 0.8 keV. The 2-10 keV luminosity of the extended emission is about one order of magnitude lower than that of the AGN. The basic physical and structural properties of the extended emission are fully consistent with a galactic wind being driven by the SB. A candidate ultraluminous X-ray source is detected 8 south of the southern nucleus. The 0.3-10 keV luminosity of this off-nuclear point source is 6 × 1040 erg s-1 if the emission is isotropic and the source is associated with the Superantennae.

Early MESSENGER Results for Less Abundant or Weakly Emitting Species in Mercury's Exosphere

NASA Technical Reports Server (NTRS)

Vervack, Ronald J., Jr.; McClintock, William E.; Killen, Rosemary M.; Sprague, Ann L.; Burger, Matthew H.; Merkel, Aimee W.; Sarantos, Menelaos

2011-01-01

Now that the Messenger spacecraft is in orbit about Mercury, the extended observing time enables searches for exospheric species that are less abundant or weakly emitting compared with those for which emission has previously been detected. Many of these species cannot be observed from the ground because of terrestrial atmospheric absorption. We report here on the status of MESSENGER orbital-phase searches for additional species in Mercury's exosphere.

Technical Problems Experienced in the Transformation of Virtual Worlds into an Education Environment and Coping Strategies

ERIC Educational Resources Information Center

Coban, Murat; Karakus, Turkan; Karaman, Asiye; Gunay, Fatma; Goktas, Yuksel

2015-01-01

Research into virtual worlds demonstrates that to successfully use virtual world platforms in different disciplines, certain limitations and potential difficulties of these platforms must be overcome. The current study extends previous research by investigating problems in integrating virtual worlds in education with a longitudinal observation of…

Measuring the Quality of Inclusive Practices: Findings from the Inclusive Classroom Profile Pilot

ERIC Educational Resources Information Center

Soukakou, Elena P.; Winton, Pam J.; West, Tracey A.; Sideris, John H.; Rucker, Lia M.

2014-01-01

The purpose of this study was to test the reliability and validity of the Inclusive Classroom Profile (ICP), an observation measure designed to assess the quality of classroom practices in inclusive preschool programs. The measure was field tested in 51 inclusive classrooms. Results confirmed and extended previous research findings, providing…

Observations of extended and counterrotating disks of ionized gas in S0 galaxies

NASA Technical Reports Server (NTRS)

Dettmar, Ralf-Juergen; Jullien-Dettmar, Marlies; Barteldrees, Andreas

1990-01-01

While many E/S0 galaxies have been found to show emission line spectra in their nuclear regions, the question of the presence and nature of extended disks of ionized gas in these galaxies has been addressed only in recent years. Typically the ionized gas is detected in the inner region on a scale of approx. 1 kpc (e.g., Phillips et al. 1986, Caldwell 1984). Here researchers present evidence that the disks of ionized gas of at least some S0 galaxies are much more extended than previously believed. In addition, with the detection of the counterrotation of gas and stars in NGC 7007 they strengthen the basis for arguments that the source of gas in S0 galaxies is external

High-frequency techniques for RCS prediction of plate geometries

NASA Technical Reports Server (NTRS)

Balanis, Constantine A.; Polka, Lesley A.

1992-01-01

The principal-plane scattering from perfectly conducting and coated strips and rectangular plates is examined. Previous reports have detailed Geometrical Theory of Diffraction/Uniform Theory of Diffraction (GTD/UTD) solutions for these geometries. The GTD/UTD solution for the perfectly conducting plate yields monostatic radar cross section (RCS) results that are nearly identical to measurements and results obtained using the Moment Method (MM) and the Extended Physical Theory of Diffraction (EPTD). This was demonstrated in previous reports. The previous analysis is extended to bistatic cases. GTD/UTD results for the principal-plane scattering from a perfectly conducting, infinite strip are compared to MM and EPTD data. A comprehensive overview of the advantages and disadvantages of the GTD/UTD and of the EPTD and a detailed analysis of the results from both methods are provided. Several previous reports also presented preliminary discussions and results for a GTD/UTD model of the RCS of a coated, rectangular plate. Several approximations for accounting for the finite coating thickness, plane-wave incidence, and far-field observation were discussed. Here, these approximations are replaced by a revised wedge diffraction coefficient that implicitly accounts for a coating on a perfect conductor, plane-wave incidence, and far-field observation. This coefficient is computationally more efficient than the previous diffraction coefficient because the number of Maliuzhinets functions that must be calculated using numerical integration is reduced by a factor of 2. The derivation and the revised coefficient are presented in detail for the hard polarization case. Computations and experimental data are also included. The soft polarization case is currently under investigation.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

NASA Astrophysics Data System (ADS)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita; Paggi, Alessandro; Raymond, John; Wang, Junfeng; Storchi-Bergmann, Thaisa

2017-07-01

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O III], [S II], and Hα, as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc) across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ˜10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include Hα evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.

Cryptic extended brood care in the facultatively eusocial sweat bee Megalopta genalis.

PubMed

Quiñones, A E; Wcislo, W T

As a result of different brood cell provisioning strategies, nest-making insects may differ in the extent to which adults regularly provide extended parental care to their brood beyond nest defense. Mass-provisioning species cache the entire food supply needed for larval development prior to the oviposition and typically seal the brood cell. It is usually assumed that there is no regular contact between the adult(s) and brood. Here, we show that the bee, Megalopta genalis , expresses a form of cryptic brood care, which would not be observed during normal development. Following experimental injections of different provisioning materials into brood cells, foundresses reopened manipulated cells and the brood were aborted in some cases, implying that the foundresses assessed conditions within the cells. In aborted cells, foundresses sometimes laid a second egg after first removing dead larvae, previously stored pollen and contaminants. Our results show that hygienic brood care can be cryptic and hence may be more widespread than previously believed, lending support to the hypothesis that extended parental care is a preadaptation toward eusociality.

VLTI/AMBER spectro-interferometry of the late-type supergiants V766 Cen (=HR 5171 A), σ Oph, BM Sco, and HD 206859

NASA Astrophysics Data System (ADS)

Wittkowski, M.; Arroyo-Torres, B.; Marcaide, J. M.; Abellan, F. J.; Chiavassa, A.; Guirado, J. C.

2017-01-01

Aims: We add four warmer late-type supergiants to our previous spectro-interferometric studies of red giants and supergiants. Methods: We measure the near-continuum angular diameter, derive fundamental parameters, discuss the evolutionary stage, and study extended atmospheric atomic and molecular layers. Results: V766 Cen (=HR 5171 A) is found to be a high-luminosity (log L/L⊙ = 5.8 ± 0.4) source of effective temperature 4290 ± 760 K and radius 1490 ± 540 R⊙, located in the Hertzsprung-Russell (HR) diagram close to both the Hayashi limit and Eddington limit; this source is consistent with a 40 M⊙ evolutionary track without rotation and current mass 27-36 M⊙. V766 Cen exhibits Na I in emission arising from a shell of radius 1.5 RPhot and a photocenter displacement of about 0.1 RPhot. It shows strong extended molecular (CO) layers and a dusty circumstellar background component. The other three sources are found to have lower luminosities of about log L/L⊙ = 3.4-3.5, corresponding to 5-9 M⊙ evolutionary tracks. They cover effective temperatures of 3900 K to 5300 K and radii of 60-120 R⊙. They do not show extended molecular layers as observed for higher luminosity RSGs of our sample. BM Sco shows an unusually strong contribution by an over-resolved circumstellar dust component. Conclusions: V766 Cen is a red supergiant located close to the Hayashi limit instead of a yellow hypergiant already evolving back toward warmer effective temperatures as discussed in the literature. Our observations of the Na I line and the extended molecular layers suggest an optically thick pseudo-photosphere at about 1.5 RPhot at the onset of the wind. The stars σ Oph, BM Sco, and HD 206859 are more likely high-mass red giants instead of RSGs as implied by their luminosity class Ib. This leaves us with an unsampled locus in the HR diagram corresponding to luminosities log L/L⊙ 3.8-4.8 or masses 10-13 M⊙, possibly corresponding to the mass region where stars explode as (type II-P) supernovae during the red supergiant stage. With V766 Cen, we now confirm that our previously found relation of increasing strength of extended molecular layers with increasing luminosities extends to double our previous luminosities and up to the Eddington limit. This might further point to steadily increasing radiative winds with increasing luminosity. Based on observations made with the VLT Interferometer (VLTI) at Paranal Observatory under program ID 093.D-0014.

The nature of the driving mechanism in the pulsating hybrid PG 1159 star Abell 43

NASA Astrophysics Data System (ADS)

Quirion, P.-O.; Fontaine, G.; Brassard, P.

2005-10-01

We extend our previous pulsational stability analyses of PG 1159 stars by modeling the hybrid PG 1159 type star Abell 43. We show that the standard κ-mechanism due to the ionization of C and O in the envelope of this H-rich PG 1159 star is perfectly able to drive g-mode pulsations. Thus, contrary to a recent suggestion, there is no need to invoke any new or exotic mechanism to explain the pulsational instabilities observed in this particular star. Our expected instability band for l=1 modes extends in period from ~2604 s to ~5529 s, which is consistent with the available photometric observations of Abell 43. We also suggest that efforts to detect luminosity variations in its sibling NGC 7094 be pursued.

The Publicly Available Prebiotic Interstellar Molecular Survey (primos): Expanding Spectroscopic Characterizations, Extending to New Sources, and Adding to the Known Molecular Inventory

NASA Astrophysics Data System (ADS)

McGuire, Brett A.; Carroll, P. Brandon; Corby, Joanna F.; Loomis, Ryan A.; Blake, Geoffrey A.; Hollis, Jan M.; Lovas, Frank J.; Jewell, Philip R.; Remijan, Anthony J.

2013-06-01

The publicly available Green Bank Telescope PRebiotic Interstellar MOlecular Survey (PRIMOS) conducted towards Sgr B2(N) provides high resolution, high-sensitivity observations with near-continuous frequency coverage from ˜300 MHz - 50 GHz. Of the eleven new molecular detections in the last year, five (45%) are a direct result of the PRIMOS observations. Further, these observations have recently been used to detect the predicted, but previously unobserved, J = 1-0 and J=2-1 transitions of the newly detected l-C_3H^+ ion. Here, we discuss the analysis of these transitions, as well as recent work to extend the PRIMOS observations to three new regions of interest: VY Canis Majoris, IRC+10216, and NGC 2023. Finally, we highlight the utility of cm-wave surveys in new molecular detections, as well as the value of publicly-available surveys in the approaching era of data-enabled, analysis-limited astrochemistry.

AGN-driven helium reionization and the incidence of extended He III regions at redshift z > 3

NASA Astrophysics Data System (ADS)

Compostella, Michele; Cantalupo, Sebastiano; Porciani, Cristiano

2014-12-01

We use hydrodynamic simulations post-processed with the radiative-transfer code RADAMESH to assess recent claims that the low He II opacity observed in z > 3 quasar spectra may be incompatible with models of He II reionization driven by the observed population of active galactic nuclei (AGNs). In particular, building upon our previous work, we consider an early population of sources and start the radiative-transfer calculation at redshifts z ≥ 5. Our model faithfully reproduces the emissivity of optically selected AGNs as inferred from measurements of their luminosity function. We find that He II reionization is very extended in redshift (Δz ≥ 2) and highly spatially inhomogeneous. In fact, mock spectra extracted from the simulations show a large variability in the evolution of the He II effective optical depth within chunks of size Δz = 0.04. Regions with low opacity (τ_ {He {II}}^eff < 3) can be found at high redshift, in agreement with the most recent observations of UV-transmitting quasars. At the highest redshift currently probed by observations (z ˜ 3.4), our updated model predicts a much lower He II effective optical depth than previous simulations in the literature relieving most of the tension with the current data, that, however, still persists at about the (Gaussian) 1σ to 2σ level. Given the very small number of observed lines of sight, our analysis indicates that current data cannot rule out a purely AGN-driven scenario with high statistical significance.

Arboreal behavior in the timber rattlesnake, Crotalus horridus, in eastern Texas

Treesearch

D. Craig Rudolph; R. R. Schaefer; D. Saenz; R. N. Conner

2004-01-01

There have been several recent reports, and anecdotal observations extending back at least to J. J. Audubon, suggesting that the timber rattlesnake (Crotalus horridus) is one of the most arboreal members of the genus. Most previous records are of snakes located at heights of less than 5 m. Telemetry studies in eastern Texas have documented more...

Effects of pH during liquid storage of goat semen on sperm viability and fertilizing potential.

PubMed

Liu, Chang-He; Dong, Hai-Bo; Ma, Dong-Li; Li, You-Wei; Han, Dong; Luo, Ming-Jiu; Chang, Zhong-Le; Tan, Jing-He

2016-01-01

A specific problem in goat semen preservation is the detrimental effect of seminal plasma on sperm viability in extenders containing yolk or milk. Thus, the use of chemically defined extenders will have obvious advantages. Although previous studies indicate that the initial pH of an extender is crucial to sustain high sperm motility, changes in extender pH during long-term semen storage have not been observed. Monitoring extender pH at different times of semen storage and modeling its variation according to nonlinear models is thus important for protocol optimization for long-term liquid semen preservation. The present results showed that during long-term liquid storage of goat semen, both sperm motility and semen pH decreased gradually, and a strong correlation was observed between the two. Whereas increasing the initial extender pH from 6.04 to 6.25 or storage with stabilized pH improved, storage with artificially lowered pH impaired sperm motility. Extender renewal improved sperm motility by maintaining a stable pH. Sperm coating with chicken (Gallus gallus) egg yolk improved motility by increasing tolerance to pH decline. A new extender (n-mZAP) with a higher buffering capacity was formulated, and n-mZAP maintained higher sperm motility, membrane integrity and acrosome intactness than the currently used mZAP extender did. Goat semen liquid-stored for 12 d in n-mZAP produced pregnancy and kidding rates similar to those obtained with freshly collected semen following artificial insemination. In conclusion, maintenance of a stable pH during liquid semen storage dramatically improved sperm viability and fertilizing potential. Copyright © 2015 Elsevier B.V. All rights reserved.

Mortality of aircraft maintenance workers exposed to trichloroethylene and other hydrocarbons and chemicals: extended follow up

PubMed Central

Radican, Larry; Blair, Aaron; Stewart, Patricia; Wartenberg, Daniel

2009-01-01

Objective To extend follow-up of 14,455 workers from 1990 to 2000, and evaluate mortality risk from exposure to trichloroethylene (TCE) and other chemicals. Methods Multivariable Cox models were used to estimate relative risk for exposed vs. unexposed workers based on previously developed exposure surrogates. Results Among TCE exposed workers, there was no statistically significant increased risk of all-cause mortality (RR=1.04) or death from all cancers (RR=1.03). Exposure-response gradients for TCE were relatively flat and did not materially change since 1990. Statistically significant excesses were found for several chemical exposure subgroups and causes, and were generally consistent with the previous follow up. Conclusions Patterns of mortality have not changed substantially since 1990. While positive associations with several cancers were observed, and are consistent with the published literature, interpretation is limited due to the small numbers of events for specific exposures. PMID:19001957

Near-IR High-Resolution Imaging Polarimetry of the SU Aur Disk: Clues for Tidal Tails?

NASA Technical Reports Server (NTRS)

De Leon, Jerome; Michihiro, Takami; Karr, Jennifer; Hashimoto, Jun; Kudo, Tomoyuki; Sitko, Michael; Mayama, Satoshi; Kusakabe, Nobuyuki; Grady, Carol A.; McElwain, Michael W.

2015-01-01

We present new high-resolution (approximately 0.09) H-band imaging observations of the circumstellar disk around the T Tauri star SU Aur. Our observations with Subaru-HiCIAO have revealed the presence of scattered light as close as 0.15 (approximately 20 AU) to the star. Within our image, we identify bright emission associated with a disk with a minimum radius of approximately 90 AU, an inclination of approximately 35 deg from the plane of the sky, and an approximate PA of 15 deg for the major axis. We find a brightness asymmetry between the northern and southern sides of the disk due to a non-axisymmetric disk structure. We also identify a pair of asymmetric tail structures extending east and west from the disk. The western tail extends at least 2. 5 (350 AU) from the star, and is probably associated with a reflection nebula previously observed at optical and near-IR wavelengths. The eastern tail extends at least 1 (140 AU) at the present signal-to-noise. These tails are likely due to an encounter with an unseen brown dwarf, but our results do not exclude the explanation that these tails are outflow cavities or jets.

Two models for a maternal factor in the inheritance of Huntington disease.

PubMed Central

Boehnke, M; Conneally, P M; Lange, K

1983-01-01

Huntington disease is a classic example of an autosomal dominant trait. Over the years, however, a number of investigators have reported anomalies regarding the age of onset of the disease that are inconsistent with this paradigm. We propose two models in which a maternal factor--cytoplasmic in one case, autosomal or X-linked in the other--acts to delay onset in a manner consistent with the previously reported anomalies. Relevant data from the Huntington's Disease Research Roster are presented that reinforce and extend the previous observations. PMID:6225335

Observing Primeval Galaxies and Dark Matter with LAIRTS

DTIC Science & Technology

1988-12-05

in the form of black holes. Previously, we had argued that the dark matter in the halo of spiral galaxies is not baryonic . Now we have extended those...consider each type of barvonic matter and show the contradictions that would exist if the dark matter were made up of each form of baryonic matter . A topic...Classification) Observing Primeval Galaxies and Dark Matter with LAIRTS 12. PERSONAL AUTHOR(S) 13a. TYPE OF REPORT 13b. TIME COVERED 14. DATE OF REPORT (Year

Multi-Wavelength Interferometric Observations of YSO Disks

NASA Astrophysics Data System (ADS)

Ragland, Sam; Akeson, R.; Armandroff, T.; Colavita, M.; Cotton, W.; Danchi, W.; Hillenbrand, L.; Millan-Gabet, R.; Ridgway, S. T.; Traub, W.; Wizinowich, P.

2010-01-01

We initiated a multi-color interferometric study of YSO disks in the K, L and N bands using the Keck Interferometer. The initial results on two Herbig Ae/Be stars will be presented. Our observations are sensitive to the radial distribution of temperature in the inner region of the YSO disks. The geometric models show that the apparent size increases linearly with wavelength, suggesting that the disk is extended with a temperature gradient. We will discuss our results in conjunction with the previous measurements of these targets.

Probing the Initial Mass Function in Extended Ultraviolet (XUV) Disks

NASA Astrophysics Data System (ADS)

Koda, Jin

2013-01-01

"The GALEX UV satellite discovered tantalizing evidence of star formation (SF) far beyond the optical edge of galactic disks (i.e. extended UV disk, or XUV disk). This discovery provides a new opportunity for studying SF in the exceedingly low-density environment (˜1/10 of typical SF density), spurring intense debate on the universality of the initial mass function (IMF) in such exceptional environments. Our pilot S-Cam study of M83’s XUV disk led to support for the universal IMF at least in M83 (Koda et al. 2012). We propose an expansion of the pilot study by about an order of magnitude, by observing 6 XUV disks in NA656(Hα), B, I, and R-band with S-Cam in S13B. In conjunction with GALEX UV bands, these images will reveal the presence of O stars (Hα) and O&B stars (UV) in stellar clusters -thus, constraining the high-mass end of the IMF. These multi-broadband images will enable us to determine the masses of the clusters with much improved accuracy (previously, relied only on R). The proposed observations will not only increase the statistical significance of our previous result, but also enable us to analyze the stochastic effect of IMF sampling in very low-mass - clusters (10^{2+3} M_sun) - the regime of ongoing debate. Previously allocated 1+2 nights were cancelled (telescope failures)."

Diary of a Wimpy Cycle

NASA Technical Reports Server (NTRS)

Hathaway, David; Upton, Lisa

2013-01-01

The cause of the low and extended minimum in solar activity between Sunspot Cycles 23 and 24 was the small size of Sunspot Cycle 24 itself - small cycles start late and leave behind low minima. Cycle 24 is small because the polar fields produced during Cycle 23 were substantially weaker than those produced during the previous cycles and those (weak) polar fields are the seeds for the activity of the following cycle. Here we discuss the observed characteristics of Cycle 24 and contrast them to the characteristics of previous cycles. We present observations and Magnetic Flux Transport simulations with data assimilated from SOHO/MDI and SDO/HMI that help to explain these differences and point the way to predictions of future activity levels.

CHEERS Results from NGC 3393. II. Investigating the Extended Narrow-line Region Using Deep Chandra Observations and Hubble Space Telescope Narrow-line Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maksym, W. Peter; Fabbiano, Giuseppina; Elvis, Martin

The CHandra Extended Emission Line Region Survey (CHEERS) is an X-ray study of nearby active galactic nuclei (AGNs) designed to take full advantage of Chandra 's unique angular resolution by spatially resolving feedback signatures and effects. In the second paper of a series on CHEERS target NGC 3393, we examine deep high-resolution Chandra images and compare them with Hubble Space Telescope narrow-line images of [O iii], [S ii], and H α , as well as previously unpublished mid-ultraviolet (MUV) images. The X-rays provide unprecedented evidence that the S-shaped arms that envelope the nuclear radio outflows extend only ≲0.″2 (≲50 pc)more » across. The high-resolution multiwavelength data suggest that the extended narrow-line region is a complex multiphase structure in the circumnuclear interstellar medium (ISM). Its ionization structure is highly stratified with respect to outflow-driven bubbles in the bicone and varies dramatically on scales of ∼10 pc. Multiple findings show likely contributions from shocks to the feedback in regions where radio outflows from the AGN most directly influence the ISM. These findings include H α evidence for gas compression and extended MUV emission and are in agreement with existing STIS kinematics. Extended filamentary structure in the X-rays and optical suggests the presence of an undetected plasma component, whose existence could be tested with deeper radio observations.« less

Inferences on mass composition and tests of hadronic interactions from 0.3 to 100 EeV using the water-Cherenkov detectors of the Pierre Auger Observatory

NASA Astrophysics Data System (ADS)

Aab, A.; Abreu, P.; Aglietta, M.; Al Samarai, I.; Albuquerque, I. F. M.; Allekotte, I.; Almela, A.; Alvarez Castillo, J.; Alvarez-Muñiz, J.; Anastasi, G. A.; Anchordoqui, L.; Andrada, B.; Andringa, S.; Aramo, C.; Arqueros, F.; Arsene, N.; Asorey, H.; Assis, P.; Aublin, J.; Avila, G.; Badescu, A. M.; Balaceanu, A.; Barbato, F.; Barreira Luz, R. J.; Beatty, J. J.; Becker, K. H.; Bellido, J. A.; Berat, C.; Bertaina, M. E.; Bertou, X.; Biermann, P. L.; Biteau, J.; Blaess, S. G.; Blanco, A.; Blazek, J.; Bleve, C.; Boháčová, M.; Boncioli, D.; Bonifazi, C.; Borodai, N.; Botti, A. M.; Brack, J.; Brancus, I.; Bretz, T.; Bridgeman, A.; Briechle, F. L.; Buchholz, P.; Bueno, A.; Buitink, S.; Buscemi, M.; Caballero-Mora, K. S.; Caccianiga, L.; Cancio, A.; Canfora, F.; Caramete, L.; Caruso, R.; Castellina, A.; Catalani, F.; Cataldi, G.; Cazon, L.; Chavez, A. G.; Chinellato, J. A.; Chudoba, J.; Clay, R. W.; Cobos, A.; Colalillo, R.; Coleman, A.; Collica, L.; Coluccia, M. R.; Conceição, R.; Consolati, G.; Contreras, F.; Cooper, M. J.; Coutu, S.; Covault, C. E.; Cronin, J.; D'Amico, S.; Daniel, B.; Dasso, S.; Daumiller, K.; Dawson, B. R.; de Almeida, R. M.; de Jong, S. J.; De Mauro, G.; de Mello Neto, J. R. T.; De Mitri, I.; de Oliveira, J.; de Souza, V.; Debatin, J.; Deligny, O.; Díaz Castro, M. L.; Diogo, F.; Dobrigkeit, C.; D'Olivo, J. C.; Dorosti, Q.; dos Anjos, R. C.; Dova, M. T.; Dundovic, A.; Ebr, J.; Engel, R.; Erdmann, M.; Erfani, M.; Escobar, C. O.; Espadanal, J.; Etchegoyen, A.; Falcke, H.; Farmer, J.; Farrar, G.; Fauth, A. C.; Fazzini, N.; Fenu, F.; Fick, B.; Figueira, J. M.; Filipčič, A.; Fratu, O.; Freire, M. M.; Fujii, T.; Fuster, A.; Gaior, R.; García, B.; Garcia-Pinto, D.; Gaté, F.; Gemmeke, H.; Gherghel-Lascu, A.; Ghia, P. L.; Giaccari, U.; Giammarchi, M.; Giller, M.; Głas, D.; Glaser, C.; Golup, G.; Gómez Berisso, M.; Gómez Vitale, P. F.; González, N.; Gorgi, A.; Gorham, P.; Grillo, A. F.; Grubb, T. D.; Guarino, F.; Guedes, G. P.; Halliday, R.; Hampel, M. R.; Hansen, P.; Harari, D.; Harrison, T. A.; Harton, J. L.; Haungs, A.; Hebbeker, T.; Heck, D.; Heimann, P.; Herve, A. E.; Hill, G. C.; Hojvat, C.; Holt, E.; Homola, P.; Hörandel, J. R.; Horvath, P.; Hrabovský, M.; Huege, T.; Hulsman, J.; Insolia, A.; Isar, P. G.; Jandt, I.; Johnsen, J. A.; Josebachuili, M.; Jurysek, J.; Kääpä, A.; Kambeitz, O.; Kampert, K. H.; Keilhauer, B.; Kemmerich, N.; Kemp, E.; Kemp, J.; Kieckhafer, R. M.; Klages, H. O.; Kleifges, M.; Kleinfeller, J.; Krause, R.; Krohm, N.; Kuempel, D.; Kukec Mezek, G.; Kunka, N.; Kuotb Awad, A.; Lago, B. L.; LaHurd, D.; Lang, R. G.; Lauscher, M.; Legumina, R.; Leigui de Oliveira, M. A.; Letessier-Selvon, A.; Lhenry-Yvon, I.; Link, K.; Lo Presti, D.; Lopes, L.; López, R.; López Casado, A.; Lorek, R.; Luce, Q.; Lucero, A.; Malacari, M.; Mallamaci, M.; Mandat, D.; Mantsch, P.; Mariazzi, A. G.; Mariş, I. C.; Marsella, G.; Martello, D.; Martinez, H.; Martínez Bravo, O.; Masías Meza, J. J.; Mathes, H. J.; Mathys, S.; Matthews, J.; Matthews, J. A. J.; Matthiae, G.; Mayotte, E.; Mazur, P. O.; Medina, C.; Medina-Tanco, G.; Melo, D.; Menshikov, A.; Merenda, K.-D.; Michal, S.; Micheletti, M. I.; Middendorf, L.; Miramonti, L.; Mitrica, B.; Mockler, D.; Mollerach, S.; Montanet, F.; Morello, C.; Mostafá, M.; Müller, A. L.; Müller, G.; Muller, M. A.; Müller, S.; Mussa, R.; Naranjo, I.; Nellen, L.; Nguyen, P. H.; Niculescu-Oglinzanu, M.; Niechciol, M.; Niemietz, L.; Niggemann, T.; Nitz, D.; Nosek, D.; Novotny, V.; Nožka, L.; Núñez, L. A.; Ochilo, L.; Oikonomou, F.; Olinto, A.; Palatka, M.; Pallotta, J.; Papenbreer, P.; Parente, G.; Parra, A.; Paul, T.; Pech, M.; Pedreira, F.; Pekala, J.; Pelayo, R.; Peña-Rodriguez, J.; Pereira, L. A. S.; Perlin, M.; Perrone, L.; Peters, C.; Petrera, S.; Phuntsok, J.; Piegaia, R.; Pierog, T.; Pimenta, M.; Pirronello, V.; Platino, M.; Plum, M.; Porowski, C.; Prado, R. R.; Privitera, P.; Prouza, M.; Quel, E. J.; Querchfeld, S.; Quinn, S.; Ramos-Pollan, R.; Rautenberg, J.; Ravignani, D.; Ridky, J.; Riehn, F.; Risse, M.; Ristori, P.; Rizi, V.; Rodrigues de Carvalho, W.; Rodriguez Fernandez, G.; Rodriguez Rojo, J.; Rogozin, D.; Roncoroni, M. J.; Roth, M.; Roulet, E.; Rovero, A. C.; Ruehl, P.; Saffi, S. J.; Saftoiu, A.; Salamida, F.; Salazar, H.; Saleh, A.; Salesa Greus, F.; Salina, G.; Sánchez, F.; Sanchez-Lucas, P.; Santos, E. M.; Santos, E.; Sarazin, F.; Sarmento, R.; Sarmiento-Cano, C.; Sato, R.; Schauer, M.; Scherini, V.; Schieler, H.; Schimp, M.; Schmidt, D.; Scholten, O.; Schovánek, P.; Schröder, F. G.; Schröder, S.; Schulz, A.; Schumacher, J.; Sciutto, S. J.; Segreto, A.; Shadkam, A.; Shellard, R. C.; Sigl, G.; Silli, G.; Sima, O.; Śmiałkowski, A.; Šmída, R.; Smith, B.; Snow, G. R.; Sommers, P.; Sonntag, S.; Squartini, R.; Stanca, D.; Stanič, S.; Stasielak, J.; Stassi, P.; Stolpovskiy, M.; Strafella, F.; Streich, A.; Suarez, F.; Suarez Durán, M.; Sudholz, T.; Suomijärvi, T.; Supanitsky, A. D.; Šupík, J.; Swain, J.; Szadkowski, Z.; Taboada, A.; Taborda, O. A.; Theodoro, V. M.; Timmermans, C.; Todero Peixoto, C. J.; Tomankova, L.; Tomé, B.; Torralba Elipe, G.; Travnicek, P.; Trini, M.; Ulrich, R.; Unger, M.; Urban, M.; Valdés Galicia, J. F.; Valiño, I.; Valore, L.; van Aar, G.; van Bodegom, P.; van den Berg, A. M.; van Vliet, A.; Varela, E.; Vargas Cárdenas, B.; Varner, G.; Vázquez, R. A.; Veberič, D.; Ventura, C.; Vergara Quispe, I. D.; Verzi, V.; Vicha, J.; Villaseñor, L.; Vorobiov, S.; Wahlberg, H.; Wainberg, O.; Walz, D.; Watson, A. A.; Weber, M.; Weindl, A.; Wiencke, L.; Wilczyński, H.; Wileman, C.; Wirtz, M.; Wittkowski, D.; Wundheiler, B.; Yang, L.; Yushkov, A.; Zas, E.; Zavrtanik, D.; Zavrtanik, M.; Zepeda, A.; Zimmermann, B.; Ziolkowski, M.; Zong, Z.; Zuccarello, F.; Pierre Auger Collaboration

2017-12-01

We present a new method for probing the hadronic interaction models at ultrahigh energy and extracting details about mass composition. This is done using the time profiles of the signals recorded with the water-Cherenkov detectors of the Pierre Auger Observatory. The profiles arise from a mix of the muon and electromagnetic components of air showers. Using the risetimes of the recorded signals, we define a new parameter, which we use to compare our observations with predictions from simulations. We find, first, inconsistencies between our data and predictions over a greater energy range and with substantially more events than in previous studies. Second, by calibrating the new parameter with fluorescence measurements from observations made at the Auger Observatory, we can infer the depth of shower maximum Xmax for a sample of over 81,000 events extending from 0.3 to over 100 EeV. Above 30 EeV, the sample is nearly 14 times larger than what is currently available from fluorescence measurements and extending the covered energy range by half a decade. The energy dependence of ⟨Xmax⟩ is compared to simulations and interpreted in terms of the mean of the logarithmic mass. We find good agreement with previous work and extend the measurement of the mean depth of shower maximum to greater energies than before, reducing significantly the statistical uncertainty associated with the inferences about mass composition.

Fermi detection of delayed GeV emission from the short gamma-ray burst 081024B

DOE PAGES

Abdo, A. A.

2010-03-03

Here, we report on the detailed analysis of the high-energy extended emission from the short gamma-ray burst (GRB) 081024B detected by the Fermi Gamma-ray Space Telescope. Historically, this represents the first clear detection of temporal extended emission from a short GRB. Furthermore, the light curve observed by the Fermi Gamma-ray Burst Monitor lasts approximately 0.8 s whereas the emission in the Fermi Large Area Telescope lasts for about 3 s. Evidence of longer lasting high-energy emission associated with long bursts has been already reported by previous experiments. These observations, together with the earlier reported study of the bright short GRBmore » 090510, indicate similarities in the high-energy emission of short and long GRBs and open the path to new interpretations.« less

EXTENDED ANALYSIS OF THE SPECTRUM OF SINGLY IONIZED CHROMIUM (Cr II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sansonetti, Craig J.; Nave, Gillian

2014-08-01

We have made new observations of the spectrum of singly ionized chromium (Cr II) in the region 2850-37900 Å with the National Institute of Standards and Technology 2 m Fourier transform spectrometer. These data extend our previously reported observations in the near-ultra-violet region. We present a comprehensive list of more than 5300 Cr II lines classified as transitions among 456 even and 457 odd levels, 179 of which are newly located in this work. Using highly excited levels of the 3d {sup 4}({sup 5} D)5g, 3d {sup 4}({sup 5} D)6g, and 3d {sup 4}({sup 5}D)6h configurations, we derive an improvedmore » ionization energy of 132971.02 ± 0.12 cm{sup –1} (16.486305 ± 0.000015 eV)« less

Notes on a General Framework for Observed Score Equating. Research Report. ETS RR-08-59

ERIC Educational Resources Information Center

Moses, Tim; Holland, Paul

2008-01-01

The purpose of this paper is to extend von Davier, Holland, and Thayer's (2004b) framework of kernel equating so that it can incorporate raw data and traditional equipercentile equating methods. One result of this more general framework is that previous equating methodology research can be viewed more comprehensively. Another result is that the…

Recent Science Highlights of the Van Allen Probes Mission

NASA Astrophysics Data System (ADS)

Ukhorskiy, Aleksandr

2016-10-01

The morning of 30 August 2012 saw an Atlas 5 rocket launch NASA's second Living With a Star spacecraft mission, the twin Radiation Belt Storm Probes, into an elliptic orbit cutting through Earth's radiation belts. Renamed the Van Allen Probes soon after launch, the Probes are designed to determine how the highly variable populations of high-energy charged particles within the radiation belts, dangerous to astronauts and satellites, are created, respond to solar variations, and evolve in space environments. The Van Allen Probes mission extends beyond the practical considerations of the hazard's of Earth's space environment. Twentieth century observations of space and astrophysical systems throughout the solar system and out into the observable universe have shown that the processes that generate intense particle radiation within magnetized environments such as Earth's are universal. During its mission the Van Allen Probes verified and quantified previously suggested energization processes, discovered new energization mechanisms, revealed the critical importance of dynamic plasma injections into the innermost magnetosphere, and used uniquely capable instruments to reveal inner radiation belt features that were all but invisible to previous sensors. This paper gives a brief overview of the mission, presents some recent science highlights, and discusses plans for the extended mission.

The XMM-Newton Survey of the Small Magellanic Cloud

NASA Technical Reports Server (NTRS)

Haberl, F.; Sturm, R.; Ballet, J.; Bomans, D. J.; Buckley, D. A. H.; Coe, M. J.; Corbet, R.; Ehle, M.; Filipovic, M. D.; Gilfanov, M.;

A Chandra Observation of the Ultraluminous Infrared Galaxy IRAS 19254-7245 (The Superantennae): X-Ray Emission from the Compton-Thick Active Galactic Nucleus and the Diffuse Starburst

NASA Technical Reports Server (NTRS)

Jia, Jianjun; Ptak, Andrew; Heckman, Timothy M.; Braito, Valentina; Reeves, James

2012-01-01

We present a Chandra observation of IRAS 19254-7245, a nearby ultraluminous infrared galaxy also known as the Superantennae. The high spatial resolution of Chandra allows us to disentangle for the first time the diffuse starburst (SB) emission from the embedded Compton-thick active galactic nucleus (AGN) in the southern nucleus. No AGN activity is detected in the northern nucleus. The 2-10 keV spectrum of the AGN emission is fitted by a flat power law (TAU = 1.3) and an He-like Fe Kalpha line with equivalent width 1.5 keV, consistent with previous observations. The Fe K line profile could be resolved as a blend of a neutral 6.4 keV line and an ionized 6.7 keV (He-like) or 6.9 keV (H-like) line. Variability of the neutral line is detected compared with the previous XMM-Newton and Suzaku observations, demonstrating the compact size of the iron line emission. The spectrum of the galaxy-scale extended emission excluding the AGN and other bright point sources is fitted with a thermal component with a best-fit kT of approximately 0.8 keV. The 2-10 keV luminosity of the extended emission is about one order of magnitude lower than that of the AGN. The basic physical and structural properties of the extended emission are fully consistent with a galactic wind being driven by the SB. A candidate ultraluminous X-ray source is detected 8 south of the southern nucleus. The 0.3 - 10 keV luminosity of this off-nuclear point source is approximately 6 x 10(exp 40) erg per second if the emission is isotropic and the source is associated with the Superantennae.

Clinical Positioning Accuracy for Multisession Stereotactic Radiotherapy With the Gamma Knife Perfexion

PubMed Central

Young, Lori A.; Phillips, Mark H.; Cheung, Michael; Halasz, Lia M.; Rockhill, Jason K.

2017-01-01

Multisession stereotactic radiation therapy is increasingly being seen as a preferred option for intracranial diseases in close proximity to critical structures and for larger target volumes. The objective of this study is to investigate the reproducibility of the Extend system from Elekta. A retrospective review was conducted for all patients treated with multisession Gamma Knife between July 2010 and June 2015, including both malignant and benign lesions. Eighty-four patients were treated in this 5-year span. The average residual daily setup uncertainty was 0.48 (0.19) mm. We compare measurements of setup uncertainty from the Extend system to measurements performed with a linac-based approach previously used in our center. The Extend system has significantly reduced setup uncertainty for fractionated intracranial treatments at our institution. Positive results were observed in a small population of edentulous patients. The Extend system compares favorably with other approaches to delivering intracranial stereotactic radiotherapy and is a robust, simple-to-use, and precise method for treating multisession intracranial lesions. PMID:28514899

Foreshock occurrence before large earthquakes

USGS Publications Warehouse

Reasenberg, P.A.

1999-01-01

Rates of foreshock occurrence involving shallow M ??? 6 and M ??? 7 mainshocks and M ??? 5 foreshocks were measured in two worldwide catalogs over ???20-year intervals. The overall rates observed are similar to ones measured in previous worldwide and regional studies when they are normalized for the ranges of magnitude difference they each span. The observed worldwide rates were compared to a generic model of earthquake clustering based on patterns of small and moderate aftershocks in California. The aftershock model was extended to the case of moderate foreshocks preceding large mainshocks. Overall, the observed worldwide foreshock rates exceed the extended California generic model by a factor of ???2. Significant differences in foreshock rate were found among subsets of earthquakes defined by their focal mechanism and tectonic region, with the rate before thrust events higher and the rate before strike-slip events lower than the worldwide average. Among the thrust events, a large majority, composed of events located in shallow subduction zones, had a high foreshock rate, while a minority, located in continental thrust belts, had a low rate. These differences may explain why previous surveys have found low foreshock rates among thrust events in California (especially southern California), while the worldwide observations suggests the opposite: California, lacking an active subduction zone in most of its territory, and including a region of mountain-building thrusts in the south, reflects the low rate apparently typical for continental thrusts, while the worldwide observations, dominated by shallow subduction zone events, are foreshock-rich. If this is so, then the California generic model may significantly underestimate the conditional probability for a very large (M ??? 8) earthquake following a potential (M ??? 7) foreshock in Cascadia. The magnitude differences among the identified foreshock-mainshock pairs in the Harvard catalog are consistent with a uniform distribution over the range of observation.

High symmetry effects on hydrogen bond rearrangement: The 4.1 THz vibrational band of (D2O)4

NASA Astrophysics Data System (ADS)

Brown, Mac G.; Keutsch, Frank N.; Braly, Linda B.; Saykally, Richard J.

1999-11-01

Vibration-rotation-tunneling (VRT) spectroscopy has been extended to the 4 THz spectral region through the observation of a second intermolecular vibration of (D2O)4. Analysis of the precisely measured perpendicular transition confirms the previously reported cyclic homodromic structure and reveals a dramatically increased (30×) hydrogen bond rearrangement rate in the excited state.

Near-infrared imaging polarimetry of dusty young stars

NASA Astrophysics Data System (ADS)

Hales, A. S.; Gledhill, T. M.; Barlow, M. J.; Lowe, K. T. E.

2006-02-01

We have carried out JHK polarimetric observations of 11 dusty young stars, by using the polarimeter module IRPOL2 with the near-infrared camera UIST on the 3.8-m United Kingdom Infrared Telescope (UKIRT). Our sample targeted systems for which UKIRT-resolvable discs had been predicted by model fits to their spectral energy distributions. Our observations have confirmed the presence of extended polarized emission around TW Hya and around HD 169142. HD 150193 and HD 142666 show the largest polarization values among our sample, but no extended structure was resolved. By combining our observations with Hubble Space Telescope (HST) coronographic data from the literature, we derive the J- and H-band intrinsic polarization radial dependences of the disc of TW Hya. We find the polarizing efficiency of the disc is higher at H than at J, and we confirm that the J- and H-band percentage polarizations are reasonably constant with radius in the region between 0.9 and 1.3arcsec from the star. We find that the objects for which we have detected extended polarizations are those for which previous modelling has suggested the presence of flared discs, which are predicted to be brighter than flat discs and thus would be easier to detect polarimetrically.

An In-depth Chandra ACIS View Of The Circumnuclear Region Of NGC 4151: The Jet, The Biconical Outflow, And A Leaky Torus

NASA Astrophysics Data System (ADS)

Wang, Junfeng; Fabbiano, G.; Elvis, M.; Risaliti, G.; Karovska, M.; Zezas, A.; Mundell, C. G.

2011-05-01

We report on the imaging analysis of 200 ks Chandra ACIS-S observations of the nearby Seyfert 1 galaxy NGC 4151. Structured soft X-ray emission is observed to extend from 30 pc to 1.5 kpc. We find strong evidence for jet-gas cloud interaction in the inner 150 pc region, confirming our previous HRC results. Self-consistent photoionization models provide good descriptions of the spectra of the optical bi-cone, supporting the dominant role of nuclear photoionization. Presence of both low and high ionization spectral components and extended emission in the X-ray image perpendicular to the bi-cone indicates leakage of nuclear ionization. Using spatially resolved features, we estimate the kinematic power of the outflow in NGC 4151 to be 0.3% of its bolometric luminosity. This work is supported by NASA grant GO8-9101X and GO1-12009X.

RR Lyrae Variables in Stellar Systems

NASA Astrophysics Data System (ADS)

Smith, Horace A.; Catelan, Márcio; Clementini, Gisella

2009-09-01

The pioneering studies of RR Lyrae stars in globular clusters by Oosterhoff and by Sawyer Hogg in the 1930s and 1940s called attention to interesting systematic differences among RR Lyrae populations in different systems. When such studies were extended to the dwarf spheroidal companions of the Milky Way in the 1960s, it was found that the average properties of their RR Lyrae stars were often different from those that had previously been observed in globular clusters. Observations of RR Lyrae stars have now extended to the Andromeda Galaxy and other Local Group systems, with still greater variety being apparent. Our understanding of the reasons for these differences among the RR Lyrae populations in different systems is by no means complete, but properties of RR Lyrae stars within these different systems are tied to differing horizontal branch morphologies and also shed light upon scenarios for the formation of the Galaxy.

An X-Ray Investigation of the NGC346 Field in the SMC (3): XMM-Newton Data

NASA Technical Reports Server (NTRS)

Naze, Yael; Manfroid, Jean; Corcoran, Michael F.; Stevens, Ian R.

2004-01-01

We present new XMM-Newton results on the field around the NGC346 star cluster in the SMC. This continues and extends previously published work on Chandra observations of the same field. The two XMM-Newton observations were obtained, respectively, six months before and six months after the previously published Chandra data. Of the 51 X-ray sources detected with XMM-Newton, 29 were already detected with Chandru. Comparing the properties of these X-ray sources in each of our three datasets has enabled us to investigate their variability on times scales of a year. Changes in the flux levels and/or spectral properties were observed for 21 of these sources. In addition, we discovered long-term variations in the X-ray properties of the peculiar system HD5980, a luminous blue variable star, that is likely to be a colliding wind binary system, which displays the largest luminosity during the first XMM-Newton observation.

People learn other people's preferences through inverse decision-making.

PubMed

Jern, Alan; Lucas, Christopher G; Kemp, Charles

2017-11-01

People are capable of learning other people's preferences by observing the choices they make. We propose that this learning relies on inverse decision-making-inverting a decision-making model to infer the preferences that led to an observed choice. In Experiment 1, participants observed 47 choices made by others and ranked them by how strongly each choice suggested that the decision maker had a preference for a specific item. An inverse decision-making model generated predictions that were in accordance with participants' inferences. Experiment 2 replicated and extended a previous study by Newtson (1974) in which participants observed pairs of choices and made judgments about which choice provided stronger evidence for a preference. Inverse decision-making again predicted the results, including a result that previous accounts could not explain. Experiment 3 used the same method as Experiment 2 and found that participants did not expect decision makers to be perfect utility-maximizers. Copyright © 2017 Elsevier B.V. All rights reserved.

Oxytocin and vasopressin effects on the neural response to social cooperation are modulated by sex in humans.

PubMed

Feng, Chunliang; Hackett, Patrick D; DeMarco, Ashley C; Chen, Xu; Stair, Sabrina; Haroon, Ebrahim; Ditzen, Beate; Pagnoni, Giuseppe; Rilling, James K

2015-12-01

Recent research has examined the effects of oxytocin (OT) and vasopressin (AVP) on human social behavior and brain function. However, most participants have been male, while previous research in our lab demonstrated sexually differentiated effects of OT and AVP on the neural response to reciprocated cooperation. Here we extend our previous work by significantly increasing the number of participants to enable the use of more stringent statistical thresholds that permit more precise localization of OT and AVP effects in the brain. In a double-blind, placebo-controlled study, 153 men and 151 women were randomized to receive 24 IU intranasal OT, 20 IU intranasal AVP or placebo. Afterwards, they were imaged with fMRI while playing an iterated Prisoner's Dilemma Game with same-sex partners. Sex differences were observed for effects of OT on the neural response to reciprocated cooperation, such that OT increased the caduate/putamen response among males, whereas it decreased this response among females. Thus, 24 IU OT may increase the reward or salience of positive social interactions among men, while decreasing their reward or salience among women. Similar sex differences were also observed for AVP effects within bilateral insula and right supramarginal gyrus when a more liberal statistical threshold was employed. While our findings support previous suggestions that exogenous nonapeptides may be effective treatments for disorders such as depression and autism spectrum disorder, they caution against uniformly extending such treatments to men and women alike.

Change Detection in Uav Video Mosaics Combining a Feature Based Approach and Extended Image Differencing

NASA Astrophysics Data System (ADS)

Saur, Günter; Krüger, Wolfgang

2016-06-01

Change detection is an important task when using unmanned aerial vehicles (UAV) for video surveillance. We address changes of short time scale using observations in time distances of a few hours. Each observation (previous and current) is a short video sequence acquired by UAV in near-Nadir view. Relevant changes are, e.g., recently parked or moved vehicles. Examples for non-relevant changes are parallaxes caused by 3D structures of the scene, shadow and illumination changes, and compression or transmission artifacts. In this paper we present (1) a new feature based approach to change detection, (2) a combination with extended image differencing (Saur et al., 2014), and (3) the application to video sequences using temporal filtering. In the feature based approach, information about local image features, e.g., corners, is extracted in both images. The label "new object" is generated at image points, where features occur in the current image and no or weaker features are present in the previous image. The label "vanished object" corresponds to missing or weaker features in the current image and present features in the previous image. This leads to two "directed" change masks and differs from image differencing where only one "undirected" change mask is extracted which combines both label types to the single label "changed object". The combination of both algorithms is performed by merging the change masks of both approaches. A color mask showing the different contributions is used for visual inspection by a human image interpreter.

TRACING INFALL AND ROTATION ALONG THE OUTFLOW CAVITY WALLS OF THE L483 PROTOSTELLAR ENVELOPE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leung, Gigi Y.C.; Lim, Jeremy; Takakuwa, Shigehisa

2016-12-10

Single-dish observations in CS(7–6) reveal emission extending out to thousands of au along the outflow axis of low-mass protostars and having a velocity gradient in the opposite direction to that of their outflows. This emission has been attributed to dense and warm gas flowing outward along the walls of bipolar outflow cavities. Here, we present combined single-dish and interferometric CS(7–6) maps for the low-mass protostar L483, revealing a newly discovered compact central component (radius ≲800 au) and previously unknown features in its extended component (visible out to ∼4000 au). The velocity gradient and skewed (toward the redshifted side) brightness distributionmore » of the extended component are detectable out to a radius of ∼2000 au, but not beyond. The compact central component exhibits a velocity gradient in the same direction as, but which is steeper than that of, the extended component. Furthermore, both components exhibit a velocity gradient with an approximately constant magnitude across the outflow axis, apparent in the extended component not just through but also away from the center out to 2000 au. We point out contradictions between our results and model predictions for outflowing gas and propose a new model in which all of the aforementioned emission can be qualitatively explained by gas inflowing along the outflow cavity walls of a rigidly rotating envelope. Our model also can explain the extended CS(7–6) emission observed around other low-mass protostars.« less

Outcomes in patients with chronic kidney disease not on dialysis receiving extended dosing regimens of darbepoetin alfa: long-term results of the EXTEND observational cohort study

PubMed Central

Galle, Jan-Christoph; Addison, Janet; Suranyi, Michael G.; Claes, Kathleen; Di Giulio, Salvatore; Guerin, Alain; Herlitz, Hans; Kiss, István; Farouk, Mourad; Manamley, Nick; Wirnsberger, Gerhard; Winearls, Christopher

2016-01-01

Background Extended dosing of the erythropoiesis-stimulating agent (ESA) darbepoetin alfa (DA) once biweekly or monthly reduces anaemia treatment burden. This observational study assessed outcomes and dosing patterns in patients with chronic kidney disease not on dialysis (CKD-NoD) commencing extended dosing of DA. Methods Adult CKD-NoD patients starting extended dosing of DA in Europe or Australia in June 2006 or later were followed up until December 2012. Outcomes included haemoglobin (Hb) concentration, ESA dosing, mortality rates and receipt of dialysis and renal transplantation. Subgroup analyses were conducted for selected outcomes. Results Of 6035 enrolled subjects, 5723 (94.8%) met analysis criteria; 1795 (29.7%) received dialysis and 238 (3.9%) underwent renal transplantation. Mean (standard deviation) Hb concentration at commencement of extended dosing was 11.0 (1.5) g/dL. Mean [95% confidence interval (CI)] Hb 12 months after commencement of extended dosing (primary outcome) was 11.6 g/dL (11.5, 11.6) overall and was similar across countries, with no differences between subjects previously treated with an ESA versus ESA-naïve subjects, subjects with versus without prior renal transplant or diabetics versus non-diabetics. Weekly ESA dose gradually decreased following commencement of extended DA dosing and was similar across subgroups. The decrease in weekly DA dose was accompanied by an increase in the proportion of patients receiving iron therapy. Hb concentrations declined following changes in ESA labels and treatment guidelines. The mortality rate (95% CI) was 7.06 (6.68, 7.46) deaths per 100 years of follow-up. Subjects alive at study end had stable Hb concentrations in the preceding year, while those who died had lower and declining Hb concentrations in their last year. Conclusions Long-term, extended dosing of DA maintained Hb concentrations in patients already treated with an ESA and corrected and maintained Hb in ESA-naïve patients. PMID:27190334

Extending the Search for Muon Neutrinos Coincident with Gamma-Ray Bursts in IceCube Data

NASA Astrophysics Data System (ADS)

Aartsen, M. G.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Ahrens, M.; Samarai, I. Al; Altmann, D.; Andeen, K.; Anderson, T.; Ansseau, I.; Anton, G.; Archinger, M.; Argüelles, C.; Auffenberg, J.; Axani, S.; Bai, X.; Barwick, S. W.; Baum, V.; Bay, R.; Beatty, J. J.; Becker Tjus, J.; Becker, K.-H.; BenZvi, S.; Berley, D.; Bernardini, E.; Besson, D. Z.; Binder, G.; Bindig, D.; Blaufuss, E.; Blot, S.; Bohm, C.; Börner, M.; Bos, F.; Bose, D.; Böser, S.; Botner, O.; Braun, J.; Brayeur, L.; Bretz, H.-P.; Bron, S.; Burgman, A.; Carver, T.; Casier, M.; Cheung, E.; Chirkin, D.; Christov, A.; Clark, K.; Classen, L.; Coenders, S.; Collin, G. H.; Conrad, J. M.; Cowen, D. F.; Cross, R.; Day, M.; de André, J. P. A. M.; De Clercq, C.; del Pino Rosendo, E.; Dembinski, H.; De Ridder, S.; Desiati, P.; de Vries, K. D.; de Wasseige, G.; de With, M.; DeYoung, T.; Díaz-Vélez, J. C.; di Lorenzo, V.; Dujmovic, H.; Dumm, J. P.; Dunkman, M.; Eberhardt, B.; Ehrhardt, T.; Eichmann, B.; Eller, P.; Euler, S.; Evenson, P. A.; Fahey, S.; Fazely, A. R.; Feintzeig, J.; Felde, J.; Filimonov, K.; Finley, C.; Flis, S.; Fösig, C.-C.; Franckowiak, A.; Friedman, E.; Fuchs, T.; Gaisser, T. K.; Gallagher, J.; Gerhardt, L.; Ghorbani, K.; Giang, W.; Gladstone, L.; Glauch, T.; Glüsenkamp, T.; Goldschmidt, A.; Gonzalez, J. G.; Grant, D.; Griffith, Z.; Haack, C.; Hallgren, A.; Halzen, F.; Hansen, E.; Hansmann, T.; Hanson, K.; Hebecker, D.; Heereman, D.; Helbing, K.; Hellauer, R.; Hickford, S.; Hignight, J.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Hoshina, K.; Huang, F.; Huber, M.; Hultqvist, K.; In, S.; Ishihara, A.; Jacobi, E.; Japaridze, G. S.; Jeong, M.; Jero, K.; Jones, B. J. P.; Kang, W.; Kappes, A.; Karg, T.; Karle, A.; Katz, U.; Kauer, M.; Keivani, A.; Kelley, J. L.; Kheirandish, A.; Kim, J.; Kim, M.; Kintscher, T.; Kiryluk, J.; Kittler, T.; Klein, S. R.; Kohnen, G.; Koirala, R.; Kolanoski, H.; Konietz, R.; Köpke, L.; Kopper, C.; Kopper, S.; Koskinen, D. J.; Kowalski, M.; Krings, K.; Kroll, M.; Krückl, G.; Krüger, C.; Kunnen, J.; Kunwar, S.; Kurahashi, N.; Kuwabara, T.; Kyriacou, A.; Labare, M.; Lanfranchi, J. L.; Larson, M. J.; Lauber, F.; Lennarz, D.; Lesiak-Bzdak, M.; Leuermann, M.; Lu, L.; Lünemann, J.; Madsen, J.; Maggi, G.; Mahn, K. B. M.; Mancina, S.; Mandelartz, M.; Maruyama, R.; Mase, K.; Maunu, R.; McNally, F.; Meagher, K.; Medici, M.; Meier, M.; Menne, T.; Merino, G.; Meures, T.; Miarecki, S.; Micallef, J.; Momenté, G.; Montaruli, T.; Moulai, M.; Nahnhauer, R.; Naumann, U.; Neer, G.; Niederhausen, H.; Nowicki, S. C.; Nygren, D. R.; Obertacke Pollmann, A.; Olivas, A.; O'Murchadha, A.; Palczewski, T.; Pandya, H.; Pankova, D. V.; Peiffer, P.; Penek, Ö.; Pepper, J. A.; Pérez de los Heros, C.; Pieloth, D.; Pinat, E.; Price, P. B.; Przybylski, G. T.; Quinnan, M.; Raab, C.; Rädel, L.; Rameez, M.; Rawlins, K.; Reimann, R.; Relethford, B.; Relich, M.; Resconi, E.; Rhode, W.; Richman, M.; Riedel, B.; Robertson, S.; Rongen, M.; Rott, C.; Ruhe, T.; Ryckbosch, D.; Rysewyk, D.; Sabbatini, L.; Sanchez Herrera, S. E.; Sandrock, A.; Sandroos, J.; Sarkar, S.; Satalecka, K.; Schlunder, P.; Schmidt, T.; Schoenen, S.; Schöneberg, S.; Schumacher, L.; Seckel, D.; Seunarine, S.; Soldin, D.; Song, M.; Spiczak, G. M.; Spiering, C.; Stachurska, J.; Stanev, T.; Stasik, A.; Stettner, J.; Steuer, A.; Stezelberger, T.; Stokstad, R. G.; Stößl, A.; Ström, R.; Strotjohann, N. L.; Sullivan, G. W.; Sutherland, M.; Taavola, H.; Taboada, I.; Tatar, J.; Tenholt, F.; Ter-Antonyan, S.; Terliuk, A.; Tešić, G.; Tilav, S.; Toale, P. A.; Tobin, M. N.; Toscano, S.; Tosi, D.; Tselengidou, M.; Tung, C. F.; Turcati, A.; Unger, E.; Usner, M.; Vandenbroucke, J.; van Eijndhoven, N.; Vanheule, S.; van Rossem, M.; van Santen, J.; Vehring, M.; Voge, M.; Vogel, E.; Vraeghe, M.; Walck, C.; Wallace, A.; Wallraff, M.; Wandkowsky, N.; Waza, A.; Weaver, Ch.; Weiss, M. J.; Wendt, C.; Westerhoff, S.; Whelan, B. J.; Wickmann, S.; Wiebe, K.; Wiebusch, C. H.; Wille, L.; Williams, D. R.; Wills, L.; Wolf, M.; Wood, T. R.; Woolsey, E.; Woschnagg, K.; Xu, D. L.; Xu, X. W.; Xu, Y.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Zoll, M.; IceCube Collaboration

2017-07-01

We present an all-sky search for muon neutrinos produced during the prompt γ-ray emission of 1172 gamma-ray bursts (GRBs) with the IceCube Neutrino Observatory. The detection of these neutrinos would constitute evidence for ultra-high-energy cosmic-ray (UHECR) production in GRBs, as interactions between accelerated protons and the prompt γ-ray field would yield charged pions, which decay to neutrinos. A previously reported search for muon neutrino tracks from northern hemisphere GRBs has been extended to include three additional years of IceCube data. A search for such tracks from southern hemisphere GRBs in five years of IceCube data has been introduced to enhance our sensitivity to the highest energy neutrinos. No significant correlation between neutrino events and observed GRBs is seen in the new data. Combining this result with previous muon neutrino track searches and a search for cascade signature events from all neutrino flavors, we obtain new constraints for single-zone fireball models of GRB neutrino and UHECR production.

Photodynamic therapy (PDT) for perianal bowenoid papulosis

NASA Astrophysics Data System (ADS)

Gahlen, Johannes; Stern, Josef; Graschew, Georgi; Kaus, Michael R.; Tilgen, W.

1995-03-01

HPV associated bowenoid papulosis of the anogenital region are classified as carcinoma in situ. The treatment can be difficult and recurrence rates are high. Extended surgical resections may have complications such as anal sphincter insufficiency. PDT does have some advantages and less side effects in the treatment of these tumors. We treated one female patient with an extended perianal bowenoid papulosis. Previous surgical resection led to local recurrence and partial sphincter insufficiency. Twenty-four hours before local laser light radiation (Ar-Dye laser, 630 nm wavelength), a systemic photosensitizer was applied (Photofrin II, 1.5 mg/kg BW). Four courses of PDT were performed within one year. We observed a total tumor necrosis in every radiation area. The previous sphincter insufficiency improved during the sessions. Side effects were rare. Pain in the radiation was stopped within 2 - 3 days under pain medication. PDT can induce a total local tumor necrosis in perianal bowenoid papulosis. Concerning local expansion, PDT can be a curable treatment.

Inferences on mass composition and tests of hadronic interactions from 0.3 to 100 EeV using the water-Cherenkov detectors of the Pierre Auger Observatory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aab, A.; Abreu, P.; Aglietta, M.

We present a new method for probing the hadronic interaction models at ultra-high energy and extracting details about mass composition. This is done using the time profiles of the signals recorded with the water-Cherenkov detectors of the Pierre Auger Observatory. The profiles arise from a mix of the muon and electromagnetic components of air-showers. Using the risetimes of the recorded signals we define a new parameter, which we use to compare our observations with predictions from simulations. We find, firstly, inconsistencies between our data and predictions over a greater energy range and with substantially more events than in previous studies.more » Secondly, by calibrating the new parameter with fluorescence measurements from observations made at the Auger Observatory, we can infer the depth of shower maximum for a sample of over 81,000 events extending from 0.3 EeV to over 100 EeV. Above 30 EeV, the sample is nearly fourteen times larger than currently available from fluorescence measurements and extending the covered energy range by half a decade. The energy dependence of the average depth of shower maximum is compared to simulations and interpreted in terms of the mean of the logarithmic mass. Here, we find good agreement with previous work and extend the measurement of the mean depth of shower maximum to greater energies than before, reducing significantly the statistical uncertainty associated with the inferences about mass composition.« less

Inferences on mass composition and tests of hadronic interactions from 0.3 to 100 EeV using the water-Cherenkov detectors of the Pierre Auger Observatory

DOE PAGES

Aab, A.; Abreu, P.; Aglietta, M.; ...

2017-12-08

We present a new method for probing the hadronic interaction models at ultra-high energy and extracting details about mass composition. This is done using the time profiles of the signals recorded with the water-Cherenkov detectors of the Pierre Auger Observatory. The profiles arise from a mix of the muon and electromagnetic components of air-showers. Using the risetimes of the recorded signals we define a new parameter, which we use to compare our observations with predictions from simulations. We find, firstly, inconsistencies between our data and predictions over a greater energy range and with substantially more events than in previous studies.more » Secondly, by calibrating the new parameter with fluorescence measurements from observations made at the Auger Observatory, we can infer the depth of shower maximum for a sample of over 81,000 events extending from 0.3 EeV to over 100 EeV. Above 30 EeV, the sample is nearly fourteen times larger than currently available from fluorescence measurements and extending the covered energy range by half a decade. The energy dependence of the average depth of shower maximum is compared to simulations and interpreted in terms of the mean of the logarithmic mass. Here, we find good agreement with previous work and extend the measurement of the mean depth of shower maximum to greater energies than before, reducing significantly the statistical uncertainty associated with the inferences about mass composition.« less

Constraining f(R) theories with cosmography

NASA Astrophysics Data System (ADS)

Anabella Teppa Pannia, Florencia; Esteban Perez Bergliaffa, Santiago

2013-08-01

A method to set constraints on the parameters of extended theories of gravitation is presented. It is based on the comparison of two series expansions of any observable that depends on H(z). The first expansion is of the cosmographical type, while the second uses the dependence of H with z furnished by a given type of extended theory. When applied to f(R) theories together with the redshift drift, the method yields limits on the parameters of two examples (the theory of Hu and Sawicki [1], and the exponential gravity introduced by Linder [2]) that are compatible with or more stringent than the existing ones, as well as a limit for a previously unconstrained parameter.

Extended Transsphenoidal Endoscopic Endonasal Surgery of Suprasellar Craniopharyngiomas.

PubMed

Fomichev, Dmitry; Kalinin, Pavel; Kutin, Maxim; Sharipov, Oleg

2016-10-01

The endoscopic extended transsphenoidal approach for suprasellar craniopharyngiomas may be a really alternative to the transcranial approach in many cases. The authors present their experience with this technique in 136 patients with craniopharyngiomas. From the past 7 years 204 patients with different purely supradiaphragmatic tumors underwent removal by extended endoscopic transsphenoidal transtuberculum transplanum approach. Most of the patients (136) had craniopharyngiomas (suprasellar, intra-extraventricular). The patients were analyzed according to age, sex, tumor size, growth and tumor structure, and clinical symptoms. Twenty-five patients had undergone a previous surgery. The mean follow-up was 42 months (range, 4-120 months). The operation is always performed with the bilateral endoscopic endonasal anterior extended transsphenoidal approach. A gross-total removal was completed in 72%. Improvement of vision or absence of visual deterioration after operation was observed in 89% of patients; 11% had worsening vision after surgery. Endocrine dysfunction did not improve after surgery, new hypotalamopituitary dysfunction (anterior pituitary dysfunction or diabetes insipidus) or worsening of it was observed in 42.6%. Other main complications included transient new mental disorder in 11%, temporary neurological postoperative deficits in 3.7%, bacterial meningitis in 16%, cerebrospinal fluid leaks in 8.8%. The recurrence rate was 20% and the lethality was 5.8%. Resection of suprasellar craniopharyngiomas using the extended endoscopic approach is a more effective and less traumatic technology, able to provide resection of the tumor along with high quality of life after surgery, and relatively rare postoperative complications and mortality. Copyright © 2016 Elsevier Inc. All rights reserved.

Optical clocks and relativity.

PubMed

Chou, C W; Hume, D B; Rosenband, T; Wineland, D J

2010-09-24

Observers in relative motion or at different gravitational potentials measure disparate clock rates. These predictions of relativity have previously been observed with atomic clocks at high velocities and with large changes in elevation. We observed time dilation from relative speeds of less than 10 meters per second by comparing two optical atomic clocks connected by a 75-meter length of optical fiber. We can now also detect time dilation due to a change in height near Earth's surface of less than 1 meter. This technique may be extended to the field of geodesy, with applications in geophysics and hydrology as well as in space-based tests of fundamental physics.

Recognition of the geologic framework of porphyry deposits on ERTS-1 imagery

NASA Technical Reports Server (NTRS)

Wilson, J. C. (Principal Investigator)

1973-01-01

The author has identified the following significant results. Photointerpretation methods have been most successfully applied in the less vegetated test sites where several previously unknown geologic features have been recognized and known ones extended. Northwest mid-Tertiary faults in the ELY, Nevada area are observed to offset north-trending ranges and abruptly terminate older Mesozoic structures. In the Ray, Arizona area the observed patterns of fault and fracture systems appear to be related to the locations of known porphyry copper deposits. In the Tanacross, Alaska area a number of regional circular features observed may represent near surface intrusions and, therefore, permissive environments for copper porphyries.

Porencephaly in a fennec fox (Vulpes zerda).

PubMed

Yamazaki, Mutsumi; Yoshimoto, Saeko; Ishikawa, Tomoko; Une, Yumi

2016-12-01

A postmortem examination revealed a large brain cavity in the right cerebral hemisphere of a 9-year-old male fennec (Vulpes zerda). The cavity was filled with cerebrospinal fluid and extended to the right lateral ventricle. Swelling and displacement of the right hippocampal area were also observed. Histologic examination revealed no evidence of previous infarct lesions, hemorrhage, inflammation or invasive tumor cells. Observation of the defective part suggested a local circulatory disorder during the fetal stage, although the cause was not detected. No neurological symptoms that could enable a provisional diagnosis were observed during the course of his life. This is the first report of asymptomatic porencephaly in a fennec fox.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yan-Rong; Wang, Jian-Min; Bai, Jin-Ming, E-mail: liyanrong@mail.ihep.ac.cn

Broad emission lines of active galactic nuclei stem from a spatially extended region (broad-line region, BLR) that is composed of discrete clouds and photoionized by the central ionizing continuum. The temporal behaviors of these emission lines are blurred echoes of continuum variations (i.e., reverberation mapping, RM) and directly reflect the structures and kinematic information of BLRs through the so-called transfer function (also known as the velocity-delay map). Based on the previous works of Rybicki and Press and Zu et al., we develop an extended, non-parametric approach to determine the transfer function for RM data, in which the transfer function ismore » expressed as a sum of a family of relatively displaced Gaussian response functions. Therefore, arbitrary shapes of transfer functions associated with complicated BLR geometry can be seamlessly included, enabling us to relax the presumption of a specified transfer function frequently adopted in previous studies and to let it be determined by observation data. We formulate our approach in a previously well-established framework that incorporates the statistical modeling of continuum variations as a damped random walk process and takes into account long-term secular variations which are irrelevant to RM signals. The application to RM data shows the fidelity of our approach.« less

ELM elimination with lithium aerosol injection in upper-single null discharges using the tungsten divertor in EAST

NASA Astrophysics Data System (ADS)

Sun, Z.; Maingi, R.; Hu, J.; Lunsford, R.; Diallo, A.; Tritz, K.; Osborne, T.; Canik, J.; Zuo, G.; Wang, L.; Xu, G.; Gong, X.; EAST Team Team

2017-10-01

A reproducible, fully non-inductive H-mode regime devoid of large ELMs has been achieved by continuous Li injection in EAST into the upper `ITER-like' tungsten divertor, extending previous results on the graphite divertor. These discharges did not suffer from density or impurity accumulation, and maintained constant core radiated power. The new results extend the energy confinement multiplier H98(y,2) 1.2, as compared to H98(y,2) 0.75 previously on the graphite divertor. The observed ELM elimination is correlated with a decrease in particle recycling, as expected from the strong Li coating before the experiment, and real-time Li aerosol injection. In addition, core W concentration was reduced during the Li injection. ELM elimination is likely related to the reduced recycling and density /temperature profile changes. A low-n electromagnetic coherent mode (MCM) at 40kHz became stronger in amplitude and also more coherent. The MCM shows strong magnetic fluctuations as measured by fast Mirnov coils, but weak density fluctuations. As compared to the graphite divertor, Li injection into the tungsten divertor eliminated ELMs at twice the previous auxiliary heating power, and reduced pedestal collisionality.

Optical and NIR spectroscopy of Mrk 1210: constraints and physical conditions of the active nucleus

NASA Astrophysics Data System (ADS)

Mazzalay, X.; Rodríguez-Ardila, A.

2007-02-01

Aims:Mrk 1210 is an outstanding Seyfert 2 galaxy because it displays signatures of recent circumnuclear star formation and a high level of X-ray activity, in addition to the classical spectral characteristics typical of an AGN. Here we investigate the extinction affecting the nuclear and extended emitting gas, the kinematics of the narrow-line region, and the physical properties and conditions of that gas. Methods: Near-infrared and optical spectra of the nuclear and extended emission region of Mrk 1210 are presented, covering the interval 0.4-2.4 μm. Emission and absorption lines were used to infer, respectively, the geometrical extension of the ionized gas and the contribution of the underlying stellar population to the observed integrated continuum. The emission line profiles were employed to study the kinematics in the NLR. The reddening and physical condition of the gas were investigated by means of flux ratios among permitted and forbidden lines. Results: The NIR nuclear spectrum is dominated by H I and He I recombination lines, as well as [S II], [S III], and [Fe II] forbidden lines. Coronal lines of [S VIII], [S IX], [Si VI], [Si X], and [Ca VIII], in addition to molecular H{2} lines, were also detected. The 12CO(6{-3)} 1.618 μm overtone bandhead helped to estimate the contribution of the stellar population to the continuum. It was found that 83±8% of the H-band continuum has a stellar origin. It improves previous estimates, which claimed that at least 50% of the observed continuum was attributed to the AGN. Analysis of the emission line profiles, both allowed and forbidden, shows a narrower ({FWHM} ˜ 500 km s-1) line on top of a broad ({FWHM} > 1000 km s-1) blue-shifted component. This seems to be associated to a nuclear outflow. This hypothesis is supported by 6 cm VLBI observations, which show a radio ejecta extending up to 30 pc from the nucleus. This result does not require the presence of the hidden BLR claimed to be present in previous NIR observations of this object. Internal extinction, calculated by means of several indicators including Fe II] flux ratios not previously used before in AGNs, reveals a dusty AGN, while the extended regions are barely affected by dust, if at all. The density and temperature are calculated for the NLR using optical and NIR lines as diagnostic ratios. The results show electronic temperatures from 10 000 K up to 40 000 K and densities between 10^3-105 cm-3. The higher temperatures show that shocks, most probably related to the radio outflow, must contribute to the line emission. Based in part in observations collected at the Pico dos Dias Observatory/LNA, Brazil. Figures 1-3 are only available in electronic form at http://www.aanda.org

Probing the Initial Mass Function in Extended Ultraviolet (XUV) Disks

NASA Astrophysics Data System (ADS)

Koda, Jin

2012-01-01

"The GALEX UV satellite discovered tantalizing evidence of star formation (SF) far beyond the optical edge of galactic disks (i.e. extended UV disk, or XUV disk). This discovery provides a new opportunity for studying SF in the exceedingly low-density environment (˜1/10 of typical SF density), spurring intense debate on the universality of the initial mass function (IMF) in such exceptional environments. Our pilot S-Cam study of M83’s XUV disk led to support for the universal IMF at least in M83 (Koda et al. 2012). We propose an expansion of the pilot study, observing 6 XUV disks in NA656(Hα), B, I, and R-band with S-Cam. In conjunction with GALEX UV bands, these images will reveal the presence of O stars (Hα; NA656-R) and O&B stars (UV) in stellar clusters -thus, constraining the high-mass end of the IMF. The multi-broadband images will enable us to determine the masses of the clusters with much improved accuracy (previously, relied only on R). The proposed observations will not only increase the statistical significance of our previous result, but also enable us to analyze the stochastic effect of IMF sampling in very low-mass clusters (10^{2+3} M_sun) - the regime about which there is much ongoing debate."

Chandra Confirmation of a Pulsar Wind Nebula in DA 495

NASA Technical Reports Server (NTRS)

Arzoumanian, Z.; Safi-Harb, S.; Landecker, T.L.; Kothes, R.; Camilo, F.

2008-01-01

As part of a multiwavelength study of the unusual radio supernova remnant DA 495, we present observations made with the Chandra X-ray Observatory. Imaging and spectroscopic analysis confirms the previously detected X-ray source at the heart of the annular radio nebula, establishing the radiative properties of two key emission components: a soft unresolved source with a blackbody temperature of 1 MK consistent with a neutron star, surrounded by a nontherma1 nebula 40" in diameter exhibiting a power-law spectrum with photon index Gamma = 1.63, typical of a pulsar wind nebula. Morphologically, the nebula appears to be slightly extended along a direction, in projection on the sky, previously demonstrated to be of significance in radio and ASCA observations; we argue that this represents the orientation of the pulsar spin axis. At smaller scales, a narrow X-ray feature is seen extending out 5" from the point source, but energetic arguments suggest that it is not the resolved termination shock of the pulsar wind against the ambient medium. Finally, we argue based on synchrotron lifetimes in the nebular magnetic field that DA 495 represents the first example of a pulsar wind nebula in which electromagnetic flux makes up a significant part, together with particle flux, of the neutron star's wind.

Cultural variation in implicit independence: An extension of Kitayama et al. ().

PubMed

Park, Jiyoung; Uchida, Yukiko; Kitayama, Shinobu

2016-08-01

Previous research shows that European Americans are consistently more independent (or less interdependent) than Japanese when implicit indices are used to assess independence (vs. interdependence). The present work extended this evidence by including a novel implicit association test (IAT), as an index of implicit attitude towards independence and interdependence. Consistent with the previous findings, as compared to Japanese, Americans were significantly higher in multiple indices of implicit independence (vs. interdependence) including personal (vs. social) self-definition, experience of disengaging (vs. engaging) emotions and personal (vs. social) form of happiness. Furthermore, as compared to Japanese, Americans had a significantly more positive implicit attitude towards independence assessed with the IAT. As also observed in the previous research, explicit measures showed inconsistent cross-cultural patterns. Lastly, we observed little statistical within-culture coherence among the implicit measures of independence (vs. interdependence), consistent with a view that the implicit indices capture alternative ways for individuals to achieve the cultural mandate of independence or interdependence. © 2015 International Union of Psychological Science.

A New Genetically Encoded Single-Chain Biosensor for Cdc42 Based on FRET, Useful for Live-Cell Imaging

PubMed Central

Cox, Dianne; Hodgson, Louis

2014-01-01

Cdc42 is critical in a myriad of cellular morphogenic processes, requiring precisely regulated activation dynamics to affect specific cellular events. To facilitate direct observations of Cdc42 activation in live cells, we developed and validated a new biosensor of Cdc42 activation. The biosensor is genetically encoded, of single-chain design and capable of correctly localizing to membrane compartments as well as interacting with its upstream regulators including the guanine nucleotide dissociation inhibitor. We characterized this new biosensor in motile mouse embryonic fibroblasts and observed robust activation dynamics at leading edge protrusions, similar to those previously observed for endogenous Cdc42 using the organic dye-based biosensor system. We then extended our validations and observations of Cdc42 activity to macrophages, and show that this new biosensor is able to detect differential activation patterns during phagocytosis and cytokine stimulation. Furthermore, we observe for the first time, a highly transient and localized activation of Cdc42 during podosome formation in macrophages, which was previously hypothesized but never directly visualized. PMID:24798463

A new genetically encoded single-chain biosensor for Cdc42 based on FRET, useful for live-cell imaging.

PubMed

Hanna, Samer; Miskolci, Veronika; Cox, Dianne; Hodgson, Louis

2014-01-01

Cdc42 is critical in a myriad of cellular morphogenic processes, requiring precisely regulated activation dynamics to affect specific cellular events. To facilitate direct observations of Cdc42 activation in live cells, we developed and validated a new biosensor of Cdc42 activation. The biosensor is genetically encoded, of single-chain design and capable of correctly localizing to membrane compartments as well as interacting with its upstream regulators including the guanine nucleotide dissociation inhibitor. We characterized this new biosensor in motile mouse embryonic fibroblasts and observed robust activation dynamics at leading edge protrusions, similar to those previously observed for endogenous Cdc42 using the organic dye-based biosensor system. We then extended our validations and observations of Cdc42 activity to macrophages, and show that this new biosensor is able to detect differential activation patterns during phagocytosis and cytokine stimulation. Furthermore, we observe for the first time, a highly transient and localized activation of Cdc42 during podosome formation in macrophages, which was previously hypothesized but never directly visualized.

High Resolution Integral Field Spectroscopy of Europa's Sodium Clouds: Evidence for a Component with Origins in Iogenic Plasma.

NASA Astrophysics Data System (ADS)

Schmidt, C.; Johnson, R. E.; Mendillo, M.; Baumgardner, J. L.; Moore, L.; O'Donoghue, J.; Leblanc, F.

2015-12-01

With the object of constraining Iogenic contributions and identifying drivers for variability, we report new observations of neutral sodium in Europa's exosphere. An R~20000 integral field spectrograph at McDonald Observatory is used to generate Doppler maps of sodium cloud structures with a resolution of 2.8 km/s/pixel. In the five nights of observations since 2011, measurements on UT 6.15-6.31 May 2015 uniquely feature fast (10s of km/s) neutral sodium clouds extending nearly 100 Europa radii, more distant than in any previous findings. During these measurements, the satellite geometry was favorable for the transfer of Na from Io to Europa, located at 1:55 to 4:00 and 3:38 to 4:39 Jovian local time, respectively. Eastward emission (away from Jupiter) extends 10-20 Europa radii retaining the moon's rest velocity, while westward emission blue-shifts with distance, and a broad range of velocities are measured, reaching at least 70 km/s at 80 Europa radii. These cloud features are distinct from Io's "banana" and "stream" features, the distant Jupiter-orbiting nebula, and from terrestrial OH and Na contaminant emissions. Io's production was quiescent during this observation, following an extremely active phase in February 2015. These results are consistent with previous findings that Europa's Na exosphere has peak emission between midnight and dawn Jovian local time and support the idea that sodium escape from Io can significantly enhance the emission intensity measured at Europa.

Extended Duration of Transgene Expression from Pegylated POD Nanoparticles Enables Attenuation of Photoreceptor Degeneration

PubMed Central

Binder, Christina; Cashman, Siobhan M.; Kumar-Singh, Rajendra

2013-01-01

Retinitis pigmentosa (RP) is the most genetically heterogeneous disorder known to cause blindness, involving over 50 different genes. Previously, we have described nanoparticles (NPs) 150 nm in size, comprised of a 3.5 kD peptide (POD) complexed to PEG and DNA (PEGPOD DNA). These NPs expressing GDNF enabled rescue of photoreceptor degeneration in mice up to 11 days post injection. In the current study we examine use of scaffold/ matrix attachment regions (S/MARs), CpG depletion and titration of DNA content of PEGPOD DNA NPs to extend the duration of transgene expression. S/MARs and CpGs did not significantly influence the duration of transgene expression, but did influence its stability. These parameters enabled us to extend transgene expression from 48 hours to 10 weeks. At 77 days post injection, we observed a 76% rescue of the thickness of the retinal outer nuclear layer (ONL) and at 37 days post injection we observed 53% and 55% rescue of the A and B wave ERG amplitudes respectively and 60% rescue of the ONL. Our studies suggest that PEGPOD DNA NPs have potential as gene delivery vectors for the retina. PMID:24278479

Effects of viscosity and constraints on the dispersion and dissipation of waves in large blood vessels. II.

NASA Technical Reports Server (NTRS)

Jones, E.; Anliker, M.; Chang, I.

1971-01-01

Comparison of previously described theoretical predictions with in vivo data from anesthetized dogs. It is shown that the observed attenuation of the pressure and axial waves cannot be accounted for by fluid viscosity alone. For large values of the frequency parameter alpha, the previous analysis is extended to include the effects of viscoelasticity of the vessel wall. The results indicate that the speeds of both types of waves are essentially unaffected by a realistic viscoelasticity model while the attenuation per wavelength is significantly increased and becomes frequency independent. There is fair agreement between theory and experiment.

Phylogenetic comparisons of a coastal bacterioplankton community with its counterparts in open ocean and freshwater systems.

PubMed

Rappé; Vergin; Giovannoni

2000-09-01

In order to extend previous comparisons between coastal marine bacterioplankton communities and their open ocean and freshwater counterparts, here we summarize and provide new data on a clone library of 105 SSU rRNA genes recovered from seawater collected over the western continental shelf of the USA in the Pacific Ocean. Comparisons to previously published data revealed that this coastal bacterioplankton clone library was dominated by SSU rRNA gene phylotypes originally described from surface waters of the open ocean, but also revealed unique SSU rRNA gene lineages of beta Proteobacteria related to those found in clone libraries from freshwater habitats. beta Proteobacteria lineages common to coastal and freshwater samples included members of a clade of obligately methylotrophic bacteria, SSU rRNA genes affiliated with Xylophilus ampelinus, and a clade related to the genus Duganella. In addition, SSU rRNA genes were recovered from such previously recognized marine bacterioplankton SSU rRNA gene clone clusters as the SAR86, SAR11, and SAR116 clusters within the class Proteobacteria, the Roseobacter clade of the alpha subclass of the Proteobacteria, the marine group A/SAR406 cluster, and the marine Actinobacteria clade. Overall, these results support and extend previous observations concerning the global distribution of several marine planktonic prokaryote SSU rRNA gene phylotypes, but also show that coastal bacterioplankton communities contain SSU rRNA gene lineages (and presumably bacterioplankton) shown previously to be prevalent in freshwater habitats.

Properties of Magnetic Reconnection as a function of magnetic shear

NASA Astrophysics Data System (ADS)

Liu, Y.; Daughton, W. S.; Karimabadi, H.; Li, H.; Gary, S. P.; Guo, F.

2013-12-01

Observations of reconnection events at the Earth's magnetopause and in the solar wind show that reconnection occurs for a large range in magnetic shear angles extending to the very low shear limit 1. Here we report a fully kinetic study of the influence of the magnetic shear on details of reconnection such as its structure and rate. In previous work, we found that the electron diffusion region bifurcates into two or more distinct layers in regimes with weak magnetic shear2, a new feature that may be observable by NASA's up-coming Magnetospheric Multiscale mission. In this work, we have systematically extended the study to lower shear cases and found a new regime, where the reconnection electric field becomes much smaller and the properties of the reconnection changes significantly. We will discuss the role of various physics mechanisms in determining the observed scaling of the reconnection rate, including the dispersive properties of the waves in the system, the dissipation mechanisms and the tearing instability. 1 J. T. Goslings and T. D. Phan. APJL 763, L39, 2013 2 Yi-Hsin Liu et al. Phys. Rev. Lett. 110 , 265004, 2013

FIRE I - Extended Time Observations Data Sets

Atmospheric Science Data Center

2017-12-21

FIRE I - Extended Time Observations Data Sets First ISCCP Regional Experiment (FIRE) I - Extended Time Observations were conducted in Utah. Relevant ... FIRE Project Guide FIRE I - Extended Time Observations Home Page (tar file) SCAR-B Block:  ...

Biological Rhythms and Temperature Regulation in Rhesus Monkeys During Spaceflight

NASA Technical Reports Server (NTRS)

Fuller, Charles A. (Principal Investigator)

1996-01-01

This program examined the influence of microgravity on temperature regulation and circadian timekeeping systems in Rhesus monkeys. Animals flown on the Soviet Biosatellite COSMOS 2229 were exposed to 11 2/3 days of microgravity. The circadian patterns temperature regulation, heart rate and activity were monitored constantly. This experiment has extended previous observations from COSMOS 1514 and 2044, as well as provided insights into the physiological mechanisms that produce these changes.

The Influence of Atmosphere-Ocean Interaction on MJO Development and Propagation

DTIC Science & Technology

2014-09-30

evaluate modeling results and process studies. The field phase of this project is associated with DYNAMO , which is the US contribution to the...influence on ocean temperature 4. Extended run for DYNAMO with high vertical resolution NCOM RESULTS Summary of project results The work funded...model experiments of the November 2011 MJO – the strongest MJO episode observed during the DYNAMO . The previous conceptual model that was based on TOGA

Large deviation principle at work: Computation of the statistical properties of the exact one-point aperture mass

NASA Astrophysics Data System (ADS)

Reimberg, Paulo; Bernardeau, Francis

2018-01-01

We present a formalism based on the large deviation principle (LDP) applied to cosmological density fields, and more specifically to the arbitrary functional of density profiles, and we apply it to the derivation of the cumulant generating function and one-point probability distribution function (PDF) of the aperture mass (Map ), a common observable for cosmic shear observations. We show that the LDP can indeed be used in practice for a much larger family of observables than previously envisioned, such as those built from continuous and nonlinear functionals of density profiles. Taking advantage of this formalism, we can extend previous results, which were based on crude definitions of the aperture mass, with top-hat windows and the use of the reduced shear approximation (replacing the reduced shear with the shear itself). We were precisely able to quantify how this latter approximation affects the Map statistical properties. In particular, we derive the corrective term for the skewness of the Map and reconstruct its one-point PDF.

Dependence of Nebular Heavy-element Abundance on H I Content for Spiral Galaxies

NASA Astrophysics Data System (ADS)

Robertson, Paul; Shields, Gregory A.; Davé, Romeel; Blanc, Guillermo A.; Wright, Audrey

2013-08-01

We analyze the galactic H I content and nebular log (O/H) for 60 spiral galaxies in the Moustakas et al. (2006a) spectral catalog. After correcting for the mass-metallicity relationship, we show that the spirals in cluster environments show a positive correlation for log (O/H) on DEF, the galactic H I deficiency parameter, extending the results of previous analyses of the Virgo and Pegasus I clusters. Additionally, we show for the first time that galaxies in the field obey a similar dependence. The observed relationship between H I deficiency and galactic metallicity resembles similar trends shown by cosmological simulations of galaxy formation including inflows and outflows. These results indicate the previously observed metallicity-DEF correlation has a more universal interpretation than simply a cluster's effects on its member galaxies. Rather, we observe in all environments the stochastic effects of metal-poor infall as minor mergers and accretion help to build giant spirals.

The Moderated Effects of Video Feedback for Social Anxiety Disorder

PubMed Central

Rodebaugh, Thomas L.; Heimberg, Richard G.; Schultz, Luke T.; Blackmore, Michelle

2010-01-01

Despite initially positive results, video feedback for social anxiety has never been shown to reduce social anxiety in a controlled experiment with diagnosed participants, and only once with undiagnosed participants. Previous studies arguably did not detect such an effect because of limited assessment of anxiety and potential moderators. We tested video feedback with cognitive preparation among treatment-seeking participants with a primary diagnosis of social anxiety disorder. In Session 1, participants gave an extemporaneous speech and either received the intervention or not. In Session 2, 6 to 14 days later, participants gave a second extemporaneous speech. The intervention improved self-perception of performance, particularly for those participants with the most unrealistically negative impressions of their performance (i.e., high self-observer discrepancy). In addition, the intervention reduced anticipatory anxiety for the second speech for participants with high self-observer discrepancy. These findings extend previous results regarding video feedback and suggest that the intervention may be useful for people with social anxiety disorder and higher self-observer discrepancies for a specific task. PMID:20471783

A separate universe view of the asymmetric sky

NASA Astrophysics Data System (ADS)

Kobayashi, Takeshi; Cortês, Marina; Liddle, Andrew R.

2015-05-01

We provide a unified description of the hemispherical asymmetry in the cosmic microwave background generated by the mechanism proposed by Erickcek, Kamionkowski, and Carroll, using a δ Script N formalism that consistently accounts for the asymmetry-generating mode throughout. We derive a general form for the power spectrum which explicitly exhibits the broken translational invariance. This can be directly compared to cosmic microwave background observables, including the observed quadrupole and fNL values, automatically incorporating the Grishchuk-Zel'dovich effect. Our calculation unifies and extends previous calculations in the literature, in particular giving the full dependence of observables on the phase of our location in the super-horizon mode that generates the asymmetry. We demonstrate how the apparently different results obtained by previous authors arise as different limiting cases. We confirm the existence of non-linear contributions to the microwave background quadrupole from the super-horizon mode identified by Erickcek et al. and further explored by Kanno et al., and show that those contributions are always significant in parameter regimes capable of explaining the observed asymmetry. We indicate example parameter values capable of explaining the observed power asymmetry without violating other observational bounds.

Porencephaly in a fennec fox (Vulpes zerda)

PubMed Central

YAMAZAKI, Mutsumi; YOSHIMOTO, Saeko; ISHIKAWA, Tomoko; UNE, Yumi

2016-01-01

A postmortem examination revealed a large brain cavity in the right cerebral hemisphere of a 9-year-old male fennec (Vulpes zerda). The cavity was filled with cerebrospinal fluid and extended to the right lateral ventricle. Swelling and displacement of the right hippocampal area were also observed. Histologic examination revealed no evidence of previous infarct lesions, hemorrhage, inflammation or invasive tumor cells. Observation of the defective part suggested a local circulatory disorder during the fetal stage, although the cause was not detected. No neurological symptoms that could enable a provisional diagnosis were observed during the course of his life. This is the first report of asymptomatic porencephaly in a fennec fox. PMID:27523321

Observed Free-Play Patterns of Children with ADHD and Their Real-Life Friends.

PubMed

Normand, Sébastien; Soucisse, Marie Michèle; Melançon, Marie Pier Vézina; Schneider, Barry H; Lee, Matthew D; Maisonneuve, Marie-France

2018-04-26

Previous observational studies conducted in highly structured, analog situations indicate that children with Attention-Deficit/Hyperactivity Disorder (ADHD) mismanage their relationships with same-age peers and friends. Such structured situations may not, however, fully represent the true nature of children's play, which is typically characterized by free choice, intrinsic motivation, and spontaneity. The unique objective of the current observational study was to describe how 87 children with ADHD and 46 comparison (76% boys) aged 7-13 years behave when interacting with their real-life dyadic friends during an unstructured, free-play situation. Results indicate that dyads comprising one referred child with ADHD and an invited friend ("ADHD dyads") engaged in less cooperative play, displayed less companionship, and showed less sensitivity to friends than comparison dyads. ADHD dyads also engaged in more conflict and exhibited significantly more negative affect than comparison dyads. These findings complement and extend, possibly with somewhat enhanced ecological validity, results obtained in previous studies on the friendships of children with ADHD featuring closed-field observations and questionnaire methodology.

Mid-latitude SuperDARN Measurements of the Extended Local Time Structure and Dynamics of Sub-Auroral Plasma Streams

NASA Astrophysics Data System (ADS)

Greenwald, R. A.; Ruohoniemi, J. M.; Shepherd, S. G.; Talaat, E. R.; Bristow, W. A.; Baker, J. B.

2011-12-01

Over the past several years, funding from the National Science Foundation Mid-Sized Infrastructure (MSI) Program has enabled the expansion of a mid-latitude network of SuperDARN HF radars. Currently the network spans the continental U.S.A and includes previously developed radars at Wallops Island and Blackstone, VA and four MSI-funded radars. Two of the MSI radars are located near Hays, Kansas and two are located near Christmas Valley, Oregon. With the current configuration of radars, it has been possible to detect sub-auroral plasma streams (SAPS), identified as latitudinally-narrow high-velocity flow regions equatorward of the main auroral electron precipitation zone, that extend over the breadth of the North American continent and the neighboring regions of the Atlantic and Pacific Oceans. SAPS have previously been reported using data from low-altitude polar-orbiting spacecraft, incoherent scatter radars, and the SuperDARN radars, but these are amongst the first observations of the SAPS velocity structure as it is observed over 6 or more hours of local time and for durations ranging up to 8 hours of real time. The SAPS flow channel is most clearly observed when there is good coupling between the solar wind and the Earth's magnetosphere (Southward IMF). As the IMF varies between southward and northward, the intensity of the flow is modulated, but the geomagnetic location of the SAPS channel does not change dramatically. To date, SAPS channels exhibiting the characteristics described above are most commonly observed under moderately disturbed conditions (Kp=3,4) and are commonly located near 60 degrees geomagnetic. The latitude of the SAPS feature decreases by several degrees between the dusk and midnight sectors. Overall, the SAPs feature appears to be an important localized flow enhancement that maps to a significant local time sector of the inner magnetosphere and it is surprisingly responsive to changes in solar-wind magnetosphere coupling. The extended ionospheric coverage provided by the SuperDARN network makes it an excellent tool to complement the data products of current and future multi-spacecraft missions.

An overview of the CalNex 2010 field mission: research to extend the understanding of climate and air quality issues in California (Invited)

NASA Astrophysics Data System (ADS)

Ryerson, T. B.

2009-12-01

CalNex is a major field study planned for May and June of 2010. The study, led by NOAA and the California Air Resources Board, coordinates many interagency partners with independent but complementary capabilities and goals. Observations from surface-, aircraft-, ship-, and space-based sensors, along with Lagrangian and Eulerian modeling studies, will be used to extend previous studies and contribute new data and understanding to issues relevant to climate change and air quality in California. This overview will present the integrated approach that will be taken in CalNex, utilizing long-term surface observations, instrumented tall towers, several major intensive ground sites, a network of daily ozonesonde launches, a radar profiling network, multiple instrumented research aircraft, a research vessel, and retrievals from several satellites. The primary CalNex science questions and experimental strategies to address them will be presented, with illustrations and data examples taken from recent field projects in California to provide context for the upcoming study.

Arene-Inserted Extended Germa[n]pericyclynes: Synthesis, Structure, and Phosphorescence Properties.

PubMed

Tanimoto, Hiroki; Mori, Junta; Ito, Shunichiro; Nishiyama, Yasuhiro; Morimoto, Tsumoru; Tanaka, Kazuo; Chujo, Yoshiki; Kakiuchi, Kiyomi

2017-07-26

This report describes the synthesis and characterization of arene-inserted extended (ArEx) germa[n]pericyclynes composed of germanium and 1,4-diethynylbenzene units. These novel cyclic germanium-π unit materials were synthesized with diethynylbenzene and germanium dichloride. X-ray crystallographic analysis revealed their structures, and the planar conformation of ArEx germa[4]pericyclyne along with the regular aromatic rings. UV/Vis absorption spectra and fluorescence emission spectra showed considerably unique and highly improved character compared to previously reported germa[n]pericyclynes. Even in the absence of transition metal components, phosphorescence emissions were observed, and the emission lifetimes were dramatically improved. ArEx germa[n]pericyclynes showed high photoluminescence quantum yields, whereas low photoluminescence quantum yields were observed for acyclic compounds. Density functional theory calculations show delocalized orbitals between skipped alkyne units through a germanium tether, and an increase in the HOMO energy level, leading to a small HOMO-LUMO energy gap. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Review of PWR fuel rod waterside corrosion behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garzarolli, F.; Jorde, D.; Manzel, R.

Waterside corrosion of Zircaloy has generally not been a problem under normal PWR operating conditions, although some instances of accelerated corrosion have been reported. However, an incentive exists to extend the average fuel rod discharge burnups to about 50,000 MWd/MTU. To minimize corrosion at these extended burnups, the factors which influence Zircaloy corrosion need to be better understood. A data base of Zircaloy corrosion behavior under PWR operating conditions has been established. The data are compiled previously published reports as well as from new Kraftwerk Union examinations. A non-destructive eddy-current technique is used to measure the oxide layer thickness onmore » fuel rods. Comparisons of measuremnts made using this eddy-current technique with those made by usual metallographic methods indicate good agreement. The data were evaluated by defining a fitting factor F which describes the increase in corrosion rate observed in-reactor over that observed from measurements of ex-reactor corrosion coupons.« less

The structure and nature of NGC 2017 IRS. 1: High-resolution radio continuum maps

NASA Technical Reports Server (NTRS)

Smith, Howard A.; Beck, Sara C.

1994-01-01

We have observed the star formation cluster NGC 2071 IRS 1, 2, and 3, with 0.14 sec spatial resolution at 2 cm. The strong source IRS 1 breaks up into a bright peak sitting on a narrow line emission extending over about 400 AU, with three much weaker peaks. This ridge, which has a p.a. = 100 deg, is not aligned with any of the other structures that have previously been seen around IRS 1: its orientation is about 55 deg from the CO outflow direction, and 35 deg from a hypothetical disk direction. The spectral and spatial results, combined with earlier radio and infrared observations, indicate that most likely the radio and infrared emission from the exciting source, IRS 1, is produced by a dense wind hidden by at least 100 visual magnitudes of extinction; the extended ridge of emission comes from an optically thin H II region with characteristic dimensions of approximately AU and which may result from a clumpy distribution of local gas and dust.

A Non-parametric Approach to Constrain the Transfer Function in Reverberation Mapping

NASA Astrophysics Data System (ADS)

Li, Yan-Rong; Wang, Jian-Min; Bai, Jin-Ming

2016-11-01

Broad emission lines of active galactic nuclei stem from a spatially extended region (broad-line region, BLR) that is composed of discrete clouds and photoionized by the central ionizing continuum. The temporal behaviors of these emission lines are blurred echoes of continuum variations (I.e., reverberation mapping, RM) and directly reflect the structures and kinematic information of BLRs through the so-called transfer function (also known as the velocity-delay map). Based on the previous works of Rybicki and Press and Zu et al., we develop an extended, non-parametric approach to determine the transfer function for RM data, in which the transfer function is expressed as a sum of a family of relatively displaced Gaussian response functions. Therefore, arbitrary shapes of transfer functions associated with complicated BLR geometry can be seamlessly included, enabling us to relax the presumption of a specified transfer function frequently adopted in previous studies and to let it be determined by observation data. We formulate our approach in a previously well-established framework that incorporates the statistical modeling of continuum variations as a damped random walk process and takes into account long-term secular variations which are irrelevant to RM signals. The application to RM data shows the fidelity of our approach.

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate.

PubMed

Vandavasi, Venu Gopal; Langan, Patricia S; Weiss, Kevin L; Parks, Jerry M; Cooper, Jonathan B; Ginell, Stephan L; Coates, Leighton

2017-01-01

The monobactam antibiotic aztreonam is used to treat cystic fibrosis patients with chronic pulmonary infections colonized by Pseudomonas aeruginosa strains expressing CTX-M extended-spectrum β-lactamases. The protonation states of active-site residues that are responsible for hydrolysis have been determined previously for the apo form of a CTX-M β-lactamase but not for a monobactam acyl-enzyme intermediate. Here we used neutron and high-resolution X-ray crystallography to probe the mechanism by which CTX-M extended-spectrum β-lactamases hydrolyze monobactam antibiotics. In these first reported structures of a class A β-lactamase in an acyl-enzyme complex with aztreonam, we directly observed most of the hydrogen atoms (as deuterium) within the active site. Although Lys 234 is fully protonated in the acyl intermediate, we found that Lys 73 is neutral. These findings are consistent with Lys 73 being able to serve as a general base during the acylation part of the catalytic mechanism, as previously proposed. Copyright © 2016 Vandavasi et al.

Emotional Stroop interference for threatening words is related to reduced EEG δ-β coupling and low attentional control.

PubMed

Putman, Peter; Arias-Garcia, Elsa; Pantazi, Ioanna; van Schie, Charlotte

2012-05-01

Previously, electroencephalographic (EEG) delta-beta coupling (positive correlation between power in the fast beta and slow delta frequency bands) has been related to affective processing. For instance, differences in delta-beta coupling have been observed between people in a psychological stress condition and controls. We previously reported relationships between attentional threat processing and delta-beta coupling and individual differences in attentional control. The present study extended and replicated these findings in a large mixed gender sample (N=80). Results demonstrated that emotional Stroop task interference for threatening words was related to self-reported attentional inhibition capacity and frontal delta-beta coupling. There was no clear gender difference for delta-beta coupling (only a non-significant trend) and the relationship between delta-beta coupling and attentional threat-processing was not affected by gender. These results replicate and extend an earlier finding concerning delta-beta coupling and cognitive affect regulation and further clarify relationships between delta-beta coupling, attentional control, and threat-processing. Copyright © 2012 Elsevier B.V. All rights reserved.

Outcomes in patients with chronic kidney disease not on dialysis receiving extended dosing regimens of darbepoetin alfa: long-term results of the EXTEND observational cohort study.

PubMed

Galle, Jan-Christoph; Addison, Janet; Suranyi, Michael G; Claes, Kathleen; Di Giulio, Salvatore; Guerin, Alain; Herlitz, Hans; Kiss, István; Farouk, Mourad; Manamley, Nick; Wirnsberger, Gerhard; Winearls, Christopher

2016-12-01

Extended dosing of the erythropoiesis-stimulating agent (ESA) darbepoetin alfa (DA) once biweekly or monthly reduces anaemia treatment burden. This observational study assessed outcomes and dosing patterns in patients with chronic kidney disease not on dialysis (CKD-NoD) commencing extended dosing of DA. Adult CKD-NoD patients starting extended dosing of DA in Europe or Australia in June 2006 or later were followed up until December 2012. Outcomes included haemoglobin (Hb) concentration, ESA dosing, mortality rates and receipt of dialysis and renal transplantation. Subgroup analyses were conducted for selected outcomes. Of 6035 enrolled subjects, 5723 (94.8%) met analysis criteria; 1795 (29.7%) received dialysis and 238 (3.9%) underwent renal transplantation. Mean (standard deviation) Hb concentration at commencement of extended dosing was 11.0 (1.5) g/dL. Mean [95% confidence interval (CI)] Hb 12 months after commencement of extended dosing (primary outcome) was 11.6 g/dL (11.5, 11.6) overall and was similar across countries, with no differences between subjects previously treated with an ESA versus ESA-naïve subjects, subjects with versus without prior renal transplant or diabetics versus non-diabetics. Weekly ESA dose gradually decreased following commencement of extended DA dosing and was similar across subgroups. The decrease in weekly DA dose was accompanied by an increase in the proportion of patients receiving iron therapy. Hb concentrations declined following changes in ESA labels and treatment guidelines. The mortality rate (95% CI) was 7.06 (6.68, 7.46) deaths per 100 years of follow-up. Subjects alive at study end had stable Hb concentrations in the preceding year, while those who died had lower and declining Hb concentrations in their last year. Long-term, extended dosing of DA maintained Hb concentrations in patients already treated with an ESA and corrected and maintained Hb in ESA-naïve patients. © The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA.

Coulomb interaction rules timescales in potassium ion channel tunneling

NASA Astrophysics Data System (ADS)

De March, N.; Prado, S. D.; Brunnet, L. G.

2018-06-01

Assuming the selectivity filter of KcsA potassium ion channel may exhibit quantum coherence, we extend a previous model by Vaziri and Plenio (2010 New J. Phys. 12 085001) to take into account Coulomb repulsion between potassium ions. We show that typical ion transit timescales are determined by this interaction, which imposes optimal input/output parameter ranges. Also, as observed in other examples of quantum tunneling in biological systems, the addition of moderate noise helps coherent ion transport.

New Measurements of High-Momentum Nucleons and Short-Range Structures in Nuclei

DOE PAGES

Fomin, N.; Arrington, J.; Asaturyan, R.; ...

2012-02-01

We present new, high-Q 2 measurements of inclusive electron scattering from high-momentum nucleons in nuclei. This yields an improved extraction of the strength of two-nucleon correlations for several nuclei, including light nuclei where clustering effects can, for the first time, be examined. The data extend to the kinematic regime where three-nucleon correlations are expected to dominate and we observe significantly greater strength in this region than previous measurements.

Band-9 ALMA Observations of the [N II] 122 μm Line and FIR Continuum in Two High-z galaxies.

NASA Astrophysics Data System (ADS)

Ferkinhoff, Carl; Brisbin, Drew; Nikola, Thomas; Stacey, Gordon J.; Sheth, Kartik; Hailey-Dunsheath, Steve; Falgarone, Edith

2015-06-01

We present Atacama Large Millimeter Array (ALMA) observations of two high-redshift systems (SMMJ02399-0136 at z 1 ˜ 2.8 and the Cloverleaf QSO at z 1 ˜ 2.5) in their rest-frame 122 μm continuum (ν sky ˜ 650 GHz, λ sky ˜ 450 μm) and [N ii] 122 μm line emission. The continuum observations with a synthesized beam of ˜0.″ 25 resolve both sources and recover the expected flux. The Cloverleaf is resolved into a partial Einstein ring, while SMMJ02399-0136 is unambiguously separated into two components: a point source associated with an active galactic nucleus and an extended region at the location of a previously identified dusty starburst. We detect the [N ii] line in both systems, though significantly weaker than our previous detections made with the first generation z (Redshift) and Early Universe Spectrometer. We show that this discrepancy is mostly explained if the line flux is resolved out due to significantly more extended emission and longer ALMA baselines than expected. Based on the ALMA observations we determine that ≥75% of the total [N ii] line flux in each source is produced via star formation. We use the [N ii] line flux that is recovered by ALMA to constrain the N/H abundance, ionized gas mass, hydrogen- ionizing photon rate, and star formation rate. In SMMJ02399-0136 we discover it contains a significant amount (˜1000 M ⊙ yr-1) of unobscured star formation in addition to its dusty starburst and argue that SMMJ02399-0136 may be similar to the Antennae Galaxies (Arp 244) locally. In total these observations provide a new look at two well-studied systems while demonstrating the power and challenges of Band-9 ALMA observations of high-z systems.

Probing the Initial Mass Function in Extended Ultraviolet (XUV) Disks

NASA Astrophysics Data System (ADS)

Koda, Jin

2013-01-01

"The GALEX UV satellite discovered tantalizing evidence of star formation (SF) far beyond the optical edge of galactic disks (i.e. extended UV disk, or XUV disk). This discovery provides a new opportunity for studying SF in the exceedingly low-density environment (˜1/10 of typical SF density), spurring intense debate on the universality of the initial mass function (IMF) in such exceptional environments. Our pilot S-Cam study of M83’s XUV disk led to support for the universal IMF at least in M83 (Koda et al. 2012). We propose an expansion of the pilot study by an order of magnitude, by observing additional 6 XUV disks in NA656(Hα), B, I, and R-band with S-Cam in S13A. In conjunction with GALEX UV bands, these images will reveal the presence of O stars (Hα; NA656-R) and O&B stars (UV) in stellar clusters -thus, constraining the high-mass end of the IMF. These multi-broadband images will enable us to determine the masses of the clusters with much improved accuracy (previously, relied only on R). The proposed observations will not only increase the statistical significance of our previous result, but also enable us to analyze the stochastic effect of IMF sampling in very low-mass - clusters (10^(2+3) M_sun) - the regime about which there is much ongoing debate."

The origin of the mid-infrared nuclear polarization of active galactic nuclei

NASA Astrophysics Data System (ADS)

Lopez-Rodriguez, E.; Alonso-Herrero, A.; Diaz-Santos, T.; Gonzalez-Martin, O.; Ichikawa, K.; Levenson, N. A.; Martinez-Paredes, M.; Nikutta, R.; Packham, C.; Perlman, E.; Almeida, C. Ramos; Rodriguez-Espinosa, J. M.; Telesco, C. M.

2018-05-01

We combine new (NGC 1275, NGC 4151, and NGC 5506) and previously published (Cygnus A, Mrk 231, and NGC 1068) sub-arcsecond resolution mid-infrared (MIR; 8-13 μm) imaging- and spectro-polarimetric observations of six Seyfert galaxies using CanariCam on the 10.4-m Gran Telescopio CANARIAS. These observations reveal a diverse set of physical processes responsible for the nuclear polarization, and permit characterization of the origin of the MIR nuclear polarimetric signature of active galactic nuclei (AGN). For all radio quiet objects, we found that the nuclear polarization is low (<1 per cent), and the degree of polarization is often a few per cent over extended regions of the host galaxy where we have sensitivity to detect such extended emission (i.e., NGC 1068 and NGC 4151). We suggest that the higher degree of polarization previously found in lower resolution data arises only on the larger-than-nuclear scales. Only the radio-loud Cygnus A exhibits significant nuclear polarization (˜11 per cent), attributable to synchrotron emission from the pc-scale jet close to the core. We present polarization models that suggest that the MIR nuclear polarization for highly obscured objects arises from a self-absorbed MIR polarized clumpy torus and/or dichroism from the host galaxy, while for unabsorbed cores, MIR polarization arises from dust scattering in the torus and/or surrounding nuclear dust.

Elemental abundance analyses with coadded DAO spectrograms. VI - The mercury-manganese stars Nu Cancri, Iota Coronae Borealis and HR 8349

NASA Technical Reports Server (NTRS)

Adelman, Saul J.

1989-01-01

The elemental abundances of three mercury-manganese stars, Nu Cancri, Iota Coronae Borealis, and HR 8349, were found to be consistent with previous analyses of this series. As Iota CrB is a double-lined spectroscopic binary with a small velocity amplitude for most of its period, its study required determining whether the observed lines were produced in the primary or secondary or both. The derived abundances and effective termperatures were used along with those of mercury-manganese stars previously analyzed in order to extend the study of probable correlations between abundances, with the effective temperature and surface gravity in accordance with radiative diffusion explanations.

LMC stellar X-ray sources observed with ROSAT. 1: X-ray data and search for optical counterparts

NASA Technical Reports Server (NTRS)

Schmidtke, P. C.; Cowley, A. P.; Frattare, L. M.; Mcgrath, T. K.

1994-01-01

Observations of Einstein Large Magellanic Cloud (LMC) X-ray point sources have been made with ROSAT's High-Resolution Imager to obtain accurate positions from which to search for optical counterparts. This paper is the first in a series reporting results of the ROSAT observations and subsequent optical observations. It includes the X-ray positions and fluxes, information about variability, optical finding charts for each source, a list of identified counterparts, and information about candidates which have been observed spectroscopically in each of the fields. Sixteen point sources were measured at a greater than 3 sigma level, while 15 other sources were either extended or less significant detections. About 50% of the sources are serendipitous detections (not found in previous surveys). More than half of the X-ray sources are variable. Sixteen of the sources have been optically identified or confirmed: six with foreground cool stars, four with Seyfert galaxies, two with signal-to-noise ratio (SNR) in the LMC, and four with peculiar hot LMC stars. Presumably the latter are all binaries, although only one (CAL 83) has been previously studied in detail.

The hubris hypothesis: The downside of comparative optimism displays.

PubMed

Hoorens, Vera; Van Damme, Carolien; Helweg-Larsen, Marie; Sedikides, Constantine

2017-04-01

According to the hubris hypothesis, observers respond more unfavorably to individuals who express their positive self-views comparatively than to those who express their positive self-views non-comparatively, because observers infer that the former hold a more disparaging view of others and particularly of observers. Two experiments extended the hubris hypothesis in the domain of optimism. Observers attributed less warmth (but not less competence) to, and showed less interest in affiliating with, an individual displaying comparative optimism (the belief that one's future will be better than others' future) than with an individual displaying absolute optimism (the belief that one's future will be good). Observers responded differently to individuals displaying comparative versus absolute optimism, because they inferred that the former held a gloomier view of the observers' future. Consistent with previous research, observers still attributed more positive traits to a comparative or absolute optimist than to a comparative or absolute pessimist. Copyright © 2016. Published by Elsevier Inc.

Candidate counterparts to the soft gamma-ray flare in the direction of LS I +61 303

NASA Astrophysics Data System (ADS)

Muñoz-Arjonilla, A. J.; Martí, J.; Combi, J. A.; Luque-Escamilla, P.; Sánchez-Sutil, J. R.; Zabalza, V.; Paredes, J. M.

2009-04-01

Context: A short duration burst reminiscent of a soft gamma-ray repeater/anomalous X-ray pulsar behaviour was detected in the direction of LS I +61 303 by the Swift satellite. While the association with this well known gamma-ray binary is likely, a different origin cannot be excluded. Aims: We explore the error box of this unexpected flaring event and establish the radio, near-infrared and X-ray sources in our search for any peculiar alternative counterpart. Methods: We carried out a combined analysis of archive Very Large Array radio data of LS I +61 303 sensitive to both compact and extended emission. We also reanalysed previous near infrared observations with the 3.5 m telescope of the Centro Astronómico Hispano Alemán and X-ray observations with the Chandra satellite. Results: Our deep radio maps of the LS I +61 303 environment represent a significant advancement on previous work and 16 compact radio sources in the LS I +61 303 vicinity are detected. For some detections, we also identify near infrared and X-ray counterparts. Extended emission features in the field are also detected and confirmed. The possible connection of some of these sources with the observed flaring event is considered. Based on these data, we are unable to claim a clear association between the Swift-BAT flare and any of the sources reported here. However, this study represents the most sophisticated attempt to determine possible alternative counterparts other than LS I +61 303.

NEW CONSTRAINTS ON MASS-DEPENDENT DISRUPTION OF STAR CLUSTERS IN M51

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chandar, Rupali; Whitmore, Bradley C.; Regan, Michael

2011-02-01

We use UBVI H{alpha} images of the Whirlpool galaxy, M51, taken with the Advanced Camera for Surveys and WFPC2 cameras on the Hubble Space Telescope (HST) to select star clusters, and to estimate their masses and ages by comparing their observed colors with predictions from population synthesis models. We construct the mass function of intermediate-age (1-4 x 10{sup 8} yr) clusters, and find that it is well described by a power law, {psi}(M) {proportional_to} M{sup {beta}}, with {beta} = -2.1 {+-} 0.2, for clusters more massive than M {approx} 6 x 10{sup 3} M{sub sun}. This extends the mass functionmore » of intermediate-age clusters in M51 to masses lower by nearly a factor of five over previous determinations. The mass function does not show evidence for curvature at either the high or low mass end. This shape indicates that there is no evidence for the earlier disruption of lower mass clusters compared with their higher mass counterparts (i.e., no mass-dependent disruption) over the observed range of masses and ages, or for a physical upper mass limit M{sub C} with which clusters in M51 can form. These conclusions differ from previous suggestions based on poorer-quality HST observations. We discuss their implications for the formation and disruption of the clusters. Ages of clusters in two 'feathers', stellar features extending from the outer portion of a spiral arm, show that the feather with a larger pitch angle formed earlier, and over a longer period, than the other.« less

Thickness of the Magnetic Crust of Mars from Magneto-Spectral Analysis

NASA Technical Reports Server (NTRS)

Voorhies, Coerte V.

2006-01-01

Previous analysis of the magnetic spectrum of Mars showed only a crustal source field. The observational spectrum was fairly well fitted by the spectrum expected from random dipolar sources scattered on a spherical shell about 46 plus or minus 10 km below Mars' 3389.5 km mean radius. This de-correlation depth overestimates the typical depth of extended magnetized structures, and so was judged closer to mean source layer thickness than twice its value. To better estimate the thickness of the magnetic crust of Mars, six different magnetic spectra were fitted with the theoretical spectrum expected from a novel, bimodal distribution of magnetic sources. This theoretical spectrum represents both compact and extended, laterally correlated sources, so source shell depth is doubled to obtain layer thickness. The typical magnetic crustal thickness is put at 47.8 plus or minus 8.2 km. The extended sources are enormous, typically 650 km across, and account for over half the magnetic energy at low degrees. How did such vast regions form?

Equation of state and high-pressure/high-temperature phase diagram of magnesium

NASA Astrophysics Data System (ADS)

Stinton, G. W.; MacLeod, S. G.; Cynn, H.; Errandonea, D.; Evans, W. J.; Proctor, J. E.; Meng, Y.; McMahon, M. I.

2014-10-01

The phase diagram of magnesium has been investigated to 211 GPa at 300 K, and to 105 GPa at 4500 K, by using a combination of x-ray diffraction and resistive and laser heating. The ambient pressure hcp structure is found to start transforming to the bcc structure at ˜45 GPa, with a large region of phase-coexistence that becomes smaller at higher temperatures. The bcc phase is stable to the highest pressures reached. The hcp-bcc phase boundary has been studied on both compression and decompression, and its slope is found to be negative and steeper than calculations have previously predicted. The laser-heating studies extend the melting curve of magnesium to 105 GPa and suggest that, at the highest pressures, the melting temperature increases more rapidly with pressure than previously reported. Finally, we observe some evidence of a new phase in the region of 10 GPa and 1200 K, where previous studies have reported a double-hexagonal-close-packed (dhcp) phase. However, the additional diffraction peaks we observe cannot be accounted for by the dhcp phase alone.

IRAS observations of chromospherically active dwarf stars

NASA Technical Reports Server (NTRS)

Tsikoudi, Vassiliki

1989-01-01

Far-infrared observations of chromospherically active, spotted, and plage stars in the dF7-dk7 spectral range are examined. Most (75 percent) of the stars have detectable 12-micron fluxes, and 50 percent of them have 25-micron emission. The 12-micron luminosity, L(12), is found to be in the range of 1.5-13 x 10 to the 30th ergs/s and to comprise only 0.2-0.5 percent of the star's total luminosity, L(bol). The present work extends to earlier spectral types and higher stellar luminosities the L(12) vs L(bol) relationship noted previously for late-type active dwarfs (K5-M5).

Extended stellar substructure surrounding the Boötes I dwarf spheroidal galaxy

NASA Astrophysics Data System (ADS)

Roderick, T. A.; Mackey, A. D.; Jerjen, H.; Da Costa, G. S.

2016-10-01

We present deep stellar photometry of the Boötes I dwarf spheroidal galaxy in g- and I-band filters, taken with the Dark Energy Camera at Cerro Tololo in Chile. Our analysis reveals a large, extended region of stellar substructure surrounding the dwarf, as well as a distinct overdensity encroaching on its tidal radius. A radial profile of the Boötes I stellar distribution shows a break radius indicating the presence of extra-tidal stars. These observations strongly suggest that Boötes I is experiencing tidal disruption, although not as extreme as that exhibited by the Hercules dwarf spheroidal. Combined with revised velocity dispersion measurements from the literature, we see evidence suggesting the need to review previous theoretical models of the Boötes I dwarf spheroidal galaxy.

Extended gamma-ray sources around pulsars constrain the origin of the positron flux at Earth

NASA Astrophysics Data System (ADS)

Abeysekara, A. U.; Albert, A.; Alfaro, R.; Alvarez, C.; Álvarez, J. D.; Arceo, R.; Arteaga-Velázquez, J. C.; Avila Rojas, D.; Ayala Solares, H. A.; Barber, A. S.; Bautista-Elivar, N.; Becerril, A.; Belmont-Moreno, E.; BenZvi, S. Y.; Berley, D.; Bernal, A.; Braun, J.; Brisbois, C.; Caballero-Mora, K. S.; Capistrán, T.; Carramiñana, A.; Casanova, S.; Castillo, M.; Cotti, U.; Cotzomi, J.; Coutiño de León, S.; De León, C.; De la Fuente, E.; Dingus, B. L.; DuVernois, M. A.; Díaz-Vélez, J. C.; Ellsworth, R. W.; Engel, K.; Enríquez-Rivera, O.; Fiorino, D. W.; Fraija, N.; García-González, J. A.; Garfias, F.; Gerhardt, M.; González Muñoz, A.; González, M. M.; Goodman, J. A.; Hampel-Arias, Z.; Harding, J. P.; Hernández, S.; Hernández-Almada, A.; Hinton, J.; Hona, B.; Hui, C. M.; Hüntemeyer, P.; Iriarte, A.; Jardin-Blicq, A.; Joshi, V.; Kaufmann, S.; Kieda, D.; Lara, A.; Lauer, R. J.; Lee, W. H.; Lennarz, D.; Vargas, H. León; Linnemann, J. T.; Longinotti, A. L.; Luis Raya, G.; Luna-García, R.; López-Coto, R.; Malone, K.; Marinelli, S. S.; Martinez, O.; Martinez-Castellanos, I.; Martínez-Castro, J.; Martínez-Huerta, H.; Matthews, J. A.; Miranda-Romagnoli, P.; Moreno, E.; Mostafá, M.; Nellen, L.; Newbold, M.; Nisa, M. U.; Noriega-Papaqui, R.; Pelayo, R.; Pretz, J.; Pérez-Pérez, E. G.; Ren, Z.; Rho, C. D.; Rivière, C.; Rosa-González, D.; Rosenberg, M.; Ruiz-Velasco, E.; Salazar, H.; Salesa Greus, F.; Sandoval, A.; Schneider, M.; Schoorlemmer, H.; Sinnis, G.; Smith, A. J.; Springer, R. W.; Surajbali, P.; Taboada, I.; Tibolla, O.; Tollefson, K.; Torres, I.; Ukwatta, T. N.; Vianello, G.; Weisgarber, T.; Westerhoff, S.; Wisher, I. G.; Wood, J.; Yapici, T.; Yodh, G.; Younk, P. W.; Zepeda, A.; Zhou, H.; Guo, F.; Hahn, J.; Li, H.; Zhang, H.

2017-11-01

The unexpectedly high flux of cosmic-ray positrons detected at Earth may originate from nearby astrophysical sources, dark matter, or unknown processes of cosmic-ray secondary production. We report the detection, using the High-Altitude Water Cherenkov Observatory (HAWC), of extended tera–electron volt gamma-ray emission coincident with the locations of two nearby middle-aged pulsars (Geminga and PSR B0656+14). The HAWC observations demonstrate that these pulsars are indeed local sources of accelerated leptons, but the measured tera–electron volt emission profile constrains the diffusion of particles away from these sources to be much slower than previously assumed. We demonstrate that the leptons emitted by these objects are therefore unlikely to be the origin of the excess positrons, which may have a more exotic origin.

The Influence of Polyethylene Glycol Solution on the Dissolution Rate of Sustained Release Morphine.

PubMed

Hodgman, Michael; Holland, Michael G; Englich, Ulrich; Wojcik, Susan M; Grant, William D; Leitner, Erich

2016-12-01

Whole bowel irrigation (WBI) is a management option for overdose of medications poorly adsorbed to activated charcoal, with modified release properties, or for body packers. Polyethylene glycol (PEG) is a mixture of ethylene oxide polymers of varying molecular weight. PEG with an average molecular weight of 3350 g/mol is used for WBI. PEG electrolyte lavage solution has been shown in vitro to hasten the dissolution of acetaminophen. The impact of PEG on the pharmacokinetics of extended release pharmaceuticals is unknown. Lower average molecular weight PEG mixtures are used as solvents and excipients. We sought to investigate the impact of PEG on the release of morphine from several extended release morphine formulations. An in vitro gastric model was developed. To test the validity of our model, we first investigated the previously described interaction of ethanol and Avinza®. Once demonstrated, we then investigated the effect of PEG with several extended release morphine formulations. In the validation portion of our study, we confirmed an ethanol Avinza® interaction. Subsequently, we did not observe accelerated release of morphine from Avinza® or generic extended release morphine in the presence of PEG. The use of PEG for gastric decontamination following ingestion of these extended release morphine formulations is unlikely to accelerate morphine release and aggravate intoxication.

Constraints on Massive Axion-Like Particles from X-ray Observations of NGC1275

NASA Astrophysics Data System (ADS)

Chen, Linhan; Conlon, Joseph P.

2018-06-01

If axion-like particles (ALPs) exist, photons can convert to ALPs on passage through regions containing magnetic fields. The magnetised intracluster medium of large galaxy clusters provides a region that is highly efficient at ALP-photon conversion. X-ray observations of Active Galactic Nuclei (AGNs) located within galaxy clusters can be used to search for and constrain ALPs, as photon-ALP conversion would lead to energy-dependent quasi-sinusoidal modulations in the X-ray spectrum of an AGN. We use Chandra observations of the central AGN of the Perseus Cluster, NGC1275, to place bounds on massive ALPs up to ma ˜ 10-11eV, extending previous work that used this dataset to constrain massless ALPs.

A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations

PubMed Central

Ganusov, Vitaly V.; De Boer, Rob J.

2013-01-01

Bromodeoxyuridine (BrdU) is widely used in immunology to detect cell division, and several mathematical models have been proposed to estimate proliferation and death rates of lymphocytes from BrdU labelling and de-labelling curves. One problem in interpreting BrdU data is explaining the de-labelling curves. Because shortly after label withdrawal, BrdU+ cells are expected to divide into BrdU+ daughter cells, one would expect a flat down-slope. As for many cell types, the fraction of BrdU+ cells decreases during de-labelling, previous mathematical models had to make debatable assumptions to be able to account for the data. We develop a mechanistic model tracking the number of divisions that each cell has undergone in the presence and absence of BrdU, and allow cells to accumulate and dilute their BrdU content. From the same mechanistic model, one can naturally derive expressions for the mean BrdU content (MBC) of all cells, or the MBC of the BrdU+ subset, which is related to the mean fluorescence intensity of BrdU that can be measured in experiments. The model is extended to include subpopulations with different rates of division and death (i.e. kinetic heterogeneity). We fit the extended model to previously published BrdU data from memory T lymphocytes in simian immunodeficiency virus-infected and uninfected macaques, and find that the model describes the data with at least the same quality as previous models. Because the same model predicts a modest decline in the MBC of BrdU+ cells, which is consistent with experimental observations, BrdU dilution seems a natural explanation for the observed down-slopes in self-renewing populations. PMID:23034350

Isolating behavioural economic indices of demand in relation to nicotine dependence.

PubMed

Chase, Henry W; Mackillop, James; Hogarth, Lee

2013-03-01

Characterisation of drug dependence using principles from behavioural economics has provided a more detailed understanding of the disorder. Although questionnaires assessing economic demand for cigarettes have extended these principles to nicotine addiction, aspects of the reliability and selectivity of these questionnaires remain uncertain. Across two experiments, we attempted to reproduce significant associations of the cigarette purchase task with nicotine dependence in a young adult population of smokers and contrasted this measure with a novel chocolate purchase task. We also examined the association between these measures and performance on a preference task, measuring preference for cigarettes and chocolate. Questionnaire measures were used within a university setting. In experiment 1, we observed associations between nicotine dependence and measures of behavioural economic demand for cigarettes, particularly O (max). In experiment 2, we replicated these findings again and extended them to show that similar correlations between nicotine dependence and demand for chocolate were not observed. Moreover, the indices of demand and choices on a concurrent choice cigarette task were moderately associated with each other and independently associated with nicotine dependence. The two experiments clearly supported previous findings regarding the association between nicotine dependence and economic demand for cigarettes. We extend these observations by showing that the generalisation of economic demand across different commodities is relatively weak, but that generalisation across different procedures is strong. Our results therefore support behavioural economic models of nicotine addiction which emphasise a robust proximal role for the incentive value of cigarettes.

"Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats".

PubMed

Valenza, Marta; Butelman, Eduardo R; Kreek, Mary Jeanne

2017-08-01

The recruitment of the stress circuitry contributes to a shift from positive to negative reinforcement mechanisms sustaining long-term cocaine addiction. The kappa opioid receptor (KOPr) signaling is upregulated by stress and chronic cocaine exposure. While KOPr agonists induce anhedonia and dysphoria, KOPr antagonists display antidepressant and anxiolytic properties. Most of the knowledge on KOPr antagonism is based on drugs with unusual pharmacokinetic and pharmacodynamic properties, complicating interpretation of results. Here we characterized in vivo behavioral and neuroendocrine effects of the novel relatively short-acting KOPr antagonist LY2444296. To date, no study has investigated whether systemic KOPr blockade reduced anxiety-like and depressive-like behaviors in animals previously exposed to chronic extended access cocaine self-administration. We tested the effect of LY2444296 in blocking KOPr-mediated aversive and neuroendocrine effects. Then, we tested acute systemic LY2444296 in reducing anxiety- and depression-like behaviors, as well as releasing the stress hormone corticosterone (CORT), observed after chronic extended access (18 h/day for 14 days) cocaine self-administration. LY2444296 blocked U69,593-induced place aversion and -reduced motor activity as well as U69,593-induced release of serum CORT, confirming its major site of action, without exerting an effect per se. Acute systemic administration of LY2444296 reduced anxiety-like and depressive-like behaviors, as well as CORT release, in rats tested after chronic extended access cocaine self-administration, but not in cocaine-naïve rats. Results suggest that acute blockade of KOPr by a relatively short-acting antagonist produces therapeutic-like effects selectively in rats with a history of chronic extended access cocaine self-administration.

Deep Chandra Observations of HCG 16. II. The Development of the Intra-group Medium in a Spiral-rich Group

NASA Astrophysics Data System (ADS)

O'Sullivan, E.; Vrtilek, J. M.; David, L. P.; Giacintucci, S.; Zezas, A.; Ponman, T. J.; Mamon, G. A.; Nulsen, P.; Raychaudhury, S.

2014-10-01

We use a combination of deep Chandra X-ray observations and radio continuum imaging to investigate the origin and current state of the intra-group medium (IGM) in the spiral-rich compact group HCG 16. We confirm the presence of a faint (L X, bolo = 1.87+1.03-0.66×1041 erg s-1), low-temperature (0.30+0.07-0.05 keV) IGM extending throughout the ACIS-S3 field of view, with a ridge linking the four original group members and extending to the southeast, as suggested by previous ROSAT and XMM-Newton observations. This ridge contains 6.6+3.9-3.3× 109 M ⊙ of hot gas and is at least partly coincident with a large-scale {H} {I} tidal filament, indicating that the IGM in the inner part of the group is highly multi-phase. We present evidence that the group is not yet virialized, and show that gas has probably been transported from the starburst winds of NGC 838 and NGC 839 into the surrounding IGM. Considering the possible origin of the IGM, we argue that material ejected by galactic winds may have played a significant role, contributing 20%-40% of the observed hot gas in the system.

First ultraviolet observations of the transition regions of X-ray bright solar-type stars in the Pleiades

NASA Technical Reports Server (NTRS)

Caillault, J.-P.; Vilhu, O.; Linsky, J. L.

1990-01-01

Results are reported from A UV study of the transition regions of two X-ray-bright solar-type stars from the Pleiades, in an attempt to extend the main sequence age baseline for the transition-region activity-age relation over more than two orders of magnitude. However, no emission lines were detected from either star; the upper limits to the fluxes are consistent with previously determined saturation levels, but do not help to further constrain evolutionary models.

Siphonophores eat fish larger than their stomachs

NASA Astrophysics Data System (ADS)

Pagès, Francesc; Madin, Laurence P.

2010-12-01

We report a collection of the siphonophore Halistemma cupulifera, collected at 20 meters depth during a night SCUBA dive in the Sargasso Sea. One of its stomachs (gastrozooids) contained a leptocephalus larva of the eel Ariosoma sp. folded in thirds to fit, but 8.3 cm in length fully extended. This finding shows that in situ observations can reveal previously unknown trophic interactions that may be significant in a changing world ocean where gelatinous organisms seem to increase at the expense of fish.

Use of A-Train Aerosol Observations to Constrain Direct Aerosol Radiative Effects (DARE) Comparisons with Aerocom Models and Uncertainty Assessments

NASA Technical Reports Server (NTRS)

Redemann, J.; Shinozuka, Y.; Kacenelenbogen, M.; Segal-Rozenhaimer, M.; LeBlanc, S.; Vaughan, M.; Stier, P.; Schutgens, N.

2017-01-01

We describe a technique for combining multiple A-Train aerosol data sets, namely MODIS spectral AOD (aerosol optical depth), OMI AAOD (absorption aerosol optical depth) and CALIOP aerosol backscatter retrievals (hereafter referred to as MOC retrievals) to estimate full spectral sets of aerosol radiative properties, and ultimately to calculate the 3-D distribution of direct aerosol radiative effects (DARE). We present MOC results using almost two years of data collected in 2007 and 2008, and show comparisons of the aerosol radiative property estimates to collocated AERONET retrievals. Use of the MODIS Collection 6 AOD data derived with the dark target and deep blue algorithms has extended the coverage of the MOC retrievals towards higher latitudes. The MOC aerosol retrievals agree better with AERONET in terms of the single scattering albedo (ssa) at 441 nm than ssa calculated from OMI and MODIS data alone, indicating that CALIOP aerosol backscatter data contains information on aerosol absorption. We compare the spatio-temporal distribution of the MOC retrievals and MOC-based calculations of seasonal clear-sky DARE to values derived from four models that participated in the Phase II AeroCom model intercomparison initiative. Overall, the MOC-based calculations of clear-sky DARE at TOA over land are smaller (less negative) than previous model or observational estimates due to the inclusion of more absorbing aerosol retrievals over brighter surfaces, not previously available for observationally-based estimates of DARE. MOC-based DARE estimates at the surface over land and total (land and ocean) DARE estimates at TOA are in between previous model and observational results. Comparisons of seasonal aerosol property to AeroCom Phase II results show generally good agreement best agreement with forcing results at TOA is found with GMI-MerraV3. We discuss sampling issues that affect the comparisons and the major challenges in extending our clear-sky DARE results to all-sky conditions. We present estimates of clear-sky and all-sky DARE and show uncertainties that stem from the assumptions in the spatial extrapolation and accuracy of aerosol and cloud properties, in the diurnal evolution of these properties, and in the radiative transfer calculations.

Comparison of North and South American biomes from AVHRR observations

NASA Technical Reports Server (NTRS)

Goward, Samuel N.; Dye, Dennis; Kerber, Arlene; Kalb, Virginia

1987-01-01

Previous analysis of the North American continent with AVHRR-derived vegetation index measurements showed a strong relation between known patterns of vegetation seasonality, productivity and the spectral vegetation index measurements. This study extends that analysis to South America to evaluate the degree to which these findings extend to tropical regions. The results show that the spectral vegetation index measurements provide a general indicator of vegetation activity across the major biomes of the Western Hemisphere of the earth, including tropical regions. The satellite-observed patterns are strongly related to the known climatology of the continents and may offer a means to improve understanding of global bioclimatology. For example, South America is shown to have a longer growing season with much earlier spring green-up than North America. The time integral of the measurements, computed from 12 composited monthly values, produces a value that is related to published net primary productivity data. However, limited net primary production data does not allow complete evaluation of satellite-observed contrasts between North and South American biomes. These results suggest that satellite-derived spectral vegetation index measurements are of great potential value in improving knowledge of the earth's biosphere.

Quantification of mutation-derived bias for alternate mating functionalities of the Saccharomyces cerevisiae Ste2p pheromone receptor.

PubMed

Choudhary, Pooja; Loewen, Michele C

2016-01-01

Although well documented for mammalian G-protein-coupled receptors, alternate functionalities and associated alternate signalling remain to be unequivocally established for the Saccharomyces cerevisiae pheromone Ste2p receptor. Here, evidence supporting alternate functionalities for Ste2p is re-evaluated, extended and quantified. In particular, strong mating and constitutive signalling mutations, focusing on residues S254, P258 and S259 in TM6 of Ste2p, are stacked and investigated in terms of their effects on classical G-protein-mediated signal transduction associated with cell cycle arrest, and alternatively, their impact on downstream mating projection and zygote formation events. In relative dose response experiments, accounting for systemic and observational bias, mutational-derived functional differences were observed, validating the S254L-derived bias for downstream mating responses and highlighting complex relationships between TM6-mutation derived constitutive signalling and ligand-induced functionalities. Mechanistically, localization studies suggest that alterations to receptor trafficking may contribute to mutational bias, in addition to expected receptor conformational stabilization effects. Overall, these results extend previous observations and quantify the contributions of Ste2p variants to mediating cell cycle arrest versus downstream mating functionalities. © Crown copyright 2015.

Ultraviolet Observations of M-Type Symbiotic Stars

NASA Astrophysics Data System (ADS)

Michalitsianos, Andrew G.

The significant differences revealed in high dispersion short wavelength spectra of two M-type symbiotic stars RW Hya (gM2 + pec) and RX Pup (M5 + pec) observed previously with IUE emphasizes the need for high resolution observations of a wide range of similar objects. The anomalies observed in high excitation lines in RX Pup of He II, N III], N IV], O III], C III], C IV and Si III] that show split line profiles, multiple component Doppler displaced components, and broadened blue wing emission structure in N III] and N IV] suggest motion in circumstellar material. In contrast, high dispersion UV spectra of RW Hya reveal narrow high excitation emission lines that give no suggestion of macroscopic motions in the circumstellar gas. We wish to extend observations of a selected number of symbiotic stars observed previously but in low resolution, to high dispersion in order to determine if particular M-type symbiotic stars exhibit anomalies in their line profile. As such, symbiotic stars exhibiting velocity structure in emission lines may form a subset of objects that are characterized by mass motions in their circumstellar envelops that create high excitation emission. UV line and continuum emission from other M-type symbiotics may arise from mainly photo-excitation processes that results from the intense radiation field associated with the hot secondary companion.

Latitude, Energy, and Time Variations of Energetic Neutral Atom Spectral indices Measured by IBEX

NASA Astrophysics Data System (ADS)

Desai, M. I.; McComas, D. J.; Dayeh, M. A.; Funsten, H. O.; Schwadron, N.; Heerikhuisen, J.; Fuselier, S. A.; Allegrini, F.; Pogorelov, N.; Zank, G. P.

2015-12-01

We investigate the latitude, energy, and time variations of the globally distributed ~0.5-6 keV energetic neutral atom (ENA) spectra measured by the Interstellar Boundary Explorer (IBEX) during the first 5 years of the mission. Our previous results based on the first 3 years of IBEX observations showed that the ENA spectral indices at the two lowest energies (~0.89 and 1.47 keV) exhibit no clear trend with ecliptic latitude θ, while those at ~2.29 and ~3.41 keV exhibit a clear latitudinal pattern; flatter spectra occur above 60° latitude and steeper spectra occur ±30° of the equator. While these results confirmed the previously reported latitudinal organization of the ENA spectra and their remarkable similarity to that of the solar wind (SW) speed observed by Ulysses in the inner heliosphere, we also showed that, unlike previous reports, the ~0.5-6 keV globally distributed ENA spectral indices could not be represented as single power laws over much of the sky, and that they depend on energy and latitude. In this work we extend the above results to include years 4 and 5 of IBEX observations and investigate if the spectral indices vary as a function of time. Finally, we discuss implications of our results on models and simulations that seek to map the IBEX ENA observations back to the latitudinal profile of the SW speed structure observed in the inner heliosphere.

Latitude, Energy, and Time Variations of Energetic Neutral Atom Spectral indices Measured by IBEX

NASA Astrophysics Data System (ADS)

Desai, Mihir; Heerikhuisen, Jacob; McComas, David; Funsten, Herbert; Pogorelov, Nikolai; Zank, Gary; Schwadron, Nathan; Fuselier, Stephen; Allegrini, Frederic; Dayeh, Maher A.

2016-07-01

We investigate the latitude, energy, and time variations of the globally distributed 0.5-6 keV energetic neutral atom (ENA) spectra measured by the Interstellar Boundary Explorer (IBEX) during the first 5 years of the mission. Our previous results based on the first 3 years of IBEX observations showed that the ENA spectral indices at the two lowest energies (0.89 and 1.47 keV) exhibit no clear trend with ecliptic latitude θ, while those at ˜2.29 and ˜3.41 keV exhibit a clear latitudinal pattern; flatter spectra occur above 60° latitude and steeper spectra occur within ±30° of the equator. While these results confirmed the previously reported latitudinal organization of the ENA spectra and their remarkable similarity to that of the solar wind (SW) speed observed by Ulysses in the inner heliosphere, we also showed that, unlike previous reports, the ˜0.5-6 keV globally distributed ENA spectral indices could not be represented as single power laws over much of the sky, and that they depend on energy and latitude. In this paper we extend the above results to include years 4 and 5 of IBEX observations and investigate if the spectral indices vary as a function of time. Finally, we discuss implications of our results on models and simulations that seek to map the IBEX ENA observations back to the latitudinal profile of the SW speed structure observed in the inner heliosphere.

A study of cooling flows in poor clusters of galaxies

NASA Technical Reports Server (NTRS)

Kriss, Gerard A.; Dillingham, Stephen

1995-01-01

We observed three poor clusters with central dominant galaxies (AWM 4, MKW 4, and MKW 3's) using the Position Sensitive Proportional Counter on the ROSAT X-ray satellite. The images reveal smooth, symmetrical X-ray emission filling the cluster with a sharp peak on each central galaxy. The cluster surface brightness profiles can be decomposed using superposed King models for the central galaxy and the intracluster medium. The King model parameters for the cluster portions are consistent with previous observations of these clusters. The newly measured King model parameters for the central galaxies are typical of the X-ray surface brightness distributions of isolated elliptical galaxies. Spatially resolved temperature measurements in annular rings throughout the clusters show a nearly isothermal profile. Temperatures are consistent with previously measured values, but are much better determined. There is no significant drop in temperature noted in the innermost bins where cooling flows are likely to be present, nor is any excess absorption by cold gas required. All cold gas columns are consistent with galactic foreground absorption. We derive mass profiles for the clusters assuming both isothermal temperature profiles and cooling flow models with constant mass flow rates. Our results are consistent with previous Einstein IPC observations by Kriss, Cioffi, & Canizares, but extend the mass profiles out to 1 Mpc in these poor clusters.

Combined search for electroweak production of charginos and neutralinos in proton-proton collisions at $$\\sqrt{s} =$$ 13 TeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sirunyan, Albert M; et al.

A statistical combination of several searches for the electroweak production of charginos and neutralinos is presented. All searches use proton-proton collision data atmore » $$\\sqrt{s}=$$ 13 TeV, recorded with the CMS detector at the LHC in 2016 and corresponding to an integrated luminosity of 35.9 fb$$^{-1}$$. In addition to the combination of previous searches, a targeted analysis requiring three or more charged leptons (electrons or muons) is presented, focusing on the challenging scenario in which the difference in mass between the two least massive neutralinos is approximately equal to the mass of the Z boson. The results are interpreted in simplified models of chargino-neutralino or neutralino pair production. For chargino-neutralino production, in the case when the lightest neutralino is massless, the combination yields an observed (expected) limit at the 95% confidence level on the chargino mass of up to 650 (570) GeV, improving upon the individual analysis limits by up to 40 GeV. If the mass difference between the two least massive neutralinos is approximately equal to the mass of the Z boson in the chargino-neutralino model, the targeted search requiring three or more leptons obtains observed and expected exclusion limits of around 225 GeV on the second neutralino mass and 125 GeV on the lightest neutralino mass, improving the observed limit by about 60 GeV in both masses compared to the previous CMS result. In the neutralino pair production model, the combined observed (expected) exclusion limit on the neutralino mass extends up to 650-750 (550-750) GeV, depending on the branching fraction assumed. This extends the observed exclusion achieved in the individual analyses by up to 200 GeV. The combined result additionally excludes some intermediate gaps in the mass coverage of the individual analyses.« less

VERY LARGE ARRAY OBSERVATIONS OF DG TAU'S RADIO JET: A HIGHLY COLLIMATED THERMAL OUTFLOW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lynch, C.; Mutel, R. L.; Gayley, K. G.

2013-03-20

The active young protostar DG Tau has an extended jet that has been well studied at radio, optical, and X-ray wavelengths. We report sensitive new Very Large Array (VLA) full-polarization observations of the core and jet between 5 GHz and 8 GHz. Our high angular resolution observation at 8 GHz clearly shows an unpolarized inner jet with a size of 42 AU (0.''35) extending along a position angle similar to the optical-X ray outer jet. Using our nearly coeval 2012 VLA observations, we find a spectral index {alpha} = +0.46 {+-} 0.05, which combined with the lack of polarization ismore » consistent with bremsstrahlung (free-free) emission, with no evidence for a non-thermal coronal component. By identifying the end of the radio jet as the optical depth unity surface, and calculating the resulting emission measure, we find that our radio results are in agreement with previous optical line studies of electron density and consequent mass-loss rate. We also detect a weak radio knot at 5 GHz located 7'' from the base of the jet, coincident with the inner radio knot detected by Rodriguez et al. in 2009 but at lower surface brightness. We interpret this as due to expansion of post-shock ionized gas in the three years between observations.« less

a Search for Interstellar Urea with Carma

NASA Astrophysics Data System (ADS)

Kuo, H.-L.; Snyder, L. E.; Friedel, D. N.; Looney, L. W.; McCall, B. J.; Remijan, A. J.; Lovas, F. J.; Hollis, J. M.

2009-06-01

Urea, a molecule discovered in human urine by H. M Rouelle in 1773, also plays a significant role in prebiotic chemistry. Previous BIMA observations have suggested that interstellar urea [(NH_2)_2CO] is a compact hot core molecule such as the other large molecules methyl formate and acetic acid (2008, 63rd OSU Symposium On Molecular Spectroscopy, RF11). We have conducted an extensive search for urea toward the high mass hot molecular core Sgr B2(N-LMH) using the CARMA array. The resolution at 1 mm enables favorable coupling of source size and synthesized beam size, which was found to be essential for flux measurements and detection limits of weak signals. The 2.5^''×2^'' synthesized beam of CARMA significantly resolves out the extended emission and reveals the weak lines that were previously blended with nearby transitions. Our analysis indicates that these lines are likely to be urea since they are now less contaminated, the resulting observed line frequencies are coincident with a set of overlapping connecting urea lines, and the observed line intensities are consistent with expected line strengths of urea.

Why emotions matter: expectancy violation and affective response mediate the emotional victim effect.

PubMed

Ask, Karl; Landström, Sara

2010-10-01

The mechanisms behind the 'emotional victim effect' (i.e., that the emotionality of a rape victim's demeanor affects perceived credibility) are relatively unexplored. In this article, a previously neglected mechanism--observers' affective response to the victim--is proposed as an alternative to the traditional expectancy-violation account. The emotional victim effect was replicated in an experiment with a sample of police trainees (N = 189), and cognitive load was found to increase the magnitude of the effect. Importantly, both compassionate affective response and expectancy violation actively mediated the emotional victim effect when the other mechanism was controlled for. These findings extend previous research on credibility judgments by introducing a 'hot' cognitive component in the judgment process. Theoretical and practical implications are discussed.

Latitude, Energy, and Time Variations of Energetic Neutral Atom Spectral indices Measured by IBEX

NASA Astrophysics Data System (ADS)

Desai, Mihir; McComas, David; Dayeh, Maher; Funsten, Herbert; Schwadron, Nathan; Heerikhuisen, Jacob; Fuselier, Stephen; Pogorelov, Nikolai; Zank, Gary; Allegrini, Frederic

2016-04-01

We investigate the latitude, energy, and time variations of the globally distributed 0.5-6 keV energetic neutral atom (ENA) spectra measured by the Interstellar Boundary Explorer (IBEX) during the first 5 years of the mission. Our previous results based on the first 3 years of IBEX observations showed that the ENA spectral indices at the two lowest energies (0.89 and 1.47 keV) exhibit no clear trend with ecliptic latitude θ, while those at ˜2.29 and ˜3.41 keV exhibit a clear latitudinal pattern; flatter spectra occur above 60° latitude and steeper spectra occur ±30° of the equator. While these results confirmed the previously reported latitudinal organization of the ENA spectra and their remarkable similarity to that of the solar wind (SW) speed observed by Ulysses in the inner heliosphere, we also showed that, unlike previous reports, the ˜0.5-6 keV globally distributed ENA spectral indices could not be represented as single power laws over much of the sky, and that they depend on energy and latitude. In this work we extend the above results to include years 4 and 5 of IBEX observations and investigate if the spectral indices vary as a function of time. Finally, we discuss implications of our results on models and simulations that seek to map the IBEX ENA observations back to the latitudinal profile of the SW speed structure observed in the inner heliosphere. We also discuss the implications of these new results for observational requirements for upcoming missions like IMAP.

Carrying capacity in a heterogeneous environment with habitat connectivity.

PubMed

Zhang, Bo; Kula, Alex; Mack, Keenan M L; Zhai, Lu; Ryce, Arrix L; Ni, Wei-Ming; DeAngelis, Donald L; Van Dyken, J David

2017-09-01

A large body of theory predicts that populations diffusing in heterogeneous environments reach higher total size than if non-diffusing, and, paradoxically, higher size than in a corresponding homogeneous environment. However, this theory and its assumptions have not been rigorously tested. Here, we extended previous theory to include exploitable resources, proving qualitatively novel results, which we tested experimentally using spatially diffusing laboratory populations of yeast. Consistent with previous theory, we predicted and experimentally observed that spatial diffusion increased total equilibrium population abundance in heterogeneous environments, with the effect size depending on the relationship between r and K. Refuting previous theory, however, we discovered that homogeneously distributed resources support higher total carrying capacity than heterogeneously distributed resources, even with species diffusion. Our results provide rigorous experimental tests of new and old theory, demonstrating how the traditional notion of carrying capacity is ambiguous for populations diffusing in spatially heterogeneous environments. © 2017 John Wiley & Sons Ltd/CNRS.

Carrying capacity in a heterogeneous environment with habitat connectivity

USGS Publications Warehouse

Zhang, Bo; Kula, Alex; Mack, Keenan M.L.; Zhai, Lu; Ryce, Arrix L.; Ni, Wei-Ming; DeAngelis, Donald L.; Van Dyken, J. David

2017-01-01

A large body of theory predicts that populations diffusing in heterogeneous environments reach higher total size than if non-diffusing, and, paradoxically, higher size than in a corresponding homogeneous environment. However, this theory and its assumptions have not been rigorously tested. Here, we extended previous theory to include exploitable resources, proving qualitatively novel results, which we tested experimentally using spatially diffusing laboratory populations of yeast. Consistent with previous theory, we predicted and experimentally observed that spatial diffusion increased total equilibrium population abundance in heterogeneous environments, with the effect size depending on the relationship between r and K. Refuting previous theory, however, we discovered that homogeneously distributed resources support higher total carrying capacity than heterogeneously distributed resources, even with species diffusion. Our results provide rigorous experimental tests of new and old theory, demonstrating how the traditional notion of carrying capacity is ambiguous for populations diffusing in spatially heterogeneous environments.

Resurgence in Siamese fighting fish, Betta splendens.

PubMed

da Silva, Stephanie P; Cançado, Carlos R X; Lattal, Kennon A

2014-03-01

Resurgence of previously reinforced responding was investigated in male Siamese fighting fish (Betta splendens). Swimming through a ring produced 15-s mirror presentations according to, with different fish, either a fixed-ratio 1 or a variable-interval 60-s schedule of reinforcement. When responding was stable, a differential-reinforcement-of-other-behavior schedule was substituted for the mirror-presentation schedule. Following this, mirror presentations were discontinued (extinction). During this latter phase, there were transient increases in the ring-swim response relative to the frequency of such responding during the differential-reinforcement-of-other behavior schedule. Resurgence was similar for the fish exposed previously to the fixed-ratio or to the variable-interval schedule. These results extend to Siamese fighting fish a well-established behavioral phenomenon previously not observed in this species or with this response topography, and only rarely reported following the removal of a non-consumable reinforcer. Copyright © 2014 Elsevier B.V. All rights reserved.

High Spectral Resolution Observation of the Soft Diffuse X-ray Background in the Direction of the Galactic Anti-Center

NASA Astrophysics Data System (ADS)

Wulf, Dallas; Eckart, Mega E.; Galeazzi, Massimiliano; Jaeckel, Felix; Kelley, Richard L.; Kilbourne, Caroline A.; McCammon, Dan; Morgan, Kelsey M.; Porter, Frederick S.; Szymkowiak, Andrew E.

2018-01-01

High spectral resolution observations in the soft x-rays are necessary for understanding and modelling the hot component of the interstellar medium and its contribution to the Soft X-ray Background (SXRB). This extended source emission cannot be resolved with most wavelength dispersive spectrometers, making energy dispersive microcalorimeters the ideal choice for these observations. We present here the analysis of the most recent sounding rocket flight of the University of Wisconsin-Madison/Goddard Space Flight Center X-ray Quantum Calorimeter (XQC), a large area silicon thermistor microcalorimeter. This 111 second observation integrates a nearly 1 steradian field of view in the direction of the galactic anti-center (l, b = 165°, -5°) and features ~5 eV spectral resolution below 1 keV. Direct comparison will also be made to the previous, high-latitude observations.

Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations.

PubMed

Cornes, Belinda K; Khor, Chiea Chuen; Nongpiur, Monisha E; Xu, Liang; Tay, Wan-Ting; Zheng, Yingfeng; Lavanya, Raghavan; Li, Yang; Wu, Renyi; Sim, Xueling; Wang, Ya-Xing; Chen, Peng; Teo, Yik Ying; Chia, Kee-Seng; Seielstad, Mark; Liu, Jianjun; Hibberd, Martin L; Cheng, Ching-Yu; Saw, Seang-Mei; Tai, E-Shyong; Jonas, Jost B; Vithana, Eranga N; Wong, Tien Y; Aung, Tin

2012-01-15

Central corneal thickness (CCT) is a highly heritable trait. Genes that significantly influence CCT can be candidate genes for common disorders in which CCT has been implicated, such as primary open-angle glaucoma (POAG) and keratoconus. Because the genetic factors controlling CCT in different Asian populations are unclear, we have built on previous work conducted on Singaporean Indians and Malays and extended our hypothesis to individuals of Chinese descent. We have followed up on all suggestive signals of association with CCT (P < 10(-4)) from the previously reported meta-analysis comprising Indians and Malays in a sample of Chinese individuals (n= 2681). In the combined sample (n= 7711), strong evidence of association was observed at four novel loci: IBTK on chromosome 6q14.1; CHSY1 on chromosome 15q26.3; and intergenic regions on chromosomes 7q11.2 and 9p23 (8.01 × 10(-11) < λ(GC) corrected P(meta) < 8.72 × 10(-8)). These four new loci explain an additional 4.3% of the total CCT variance across the sample cohorts over and above that of previously identified loci. We also extend on a previous finding at a fifth locus (AKAP13) where a new single-nucleotide polymorphism (rs1821481, P(meta) = 9.99 × 10(-9)) was found to be significantly more informative compared with the previously reported rs6496932 (P(meta) = 3.64 × 10(-5)). Performing association analysis in Asians may lead to the discovery of ethnic-specific genes that control CCT, offering further mechanistic insights into the regulation of CCT. In addition, it may also provide several candidate genes for interrogation for POAG, keratoconus and possible racial/ethnic variations. © The Author 2011. Published by Oxford University Press. All rights reserved.

Texes Observations of M Supergiants: Dynamics and Thermodynamics of Wind Acceleration

NASA Astrophysics Data System (ADS)

Harper, Graham M.; Richter, Matthew J.; Ryde, Nils; Brown, Alexander; Brown, Joanna; Greathouse, Thomas K.; Strong, Shadrian

2009-08-01

We have detected [Fe II] 17.94 μm and 24.52 μm emission from a sample of M supergiants (μ Cep, α Sco, α Ori, CE Tau, AD Per, and α Her) using the Texas Echelon Cross Echelle Spectrograph on NASA's Infrared Telescope Facility. These low opacity emission lines are resolved at R sime 50, 000 and provide new diagnostics of the dynamics and thermodynamics of the stellar wind acceleration zone. The [Fe II] lines, from the first excited term (a 4 F), are sensitive to the warm plasma where energy is deposited into the extended atmosphere to form the chromosphere and wind outflow. These diagnostics complement previous Kuiper Airborne Observatory and Infrared Space Observatory observations which were sensitive to the cooler and more extended circumstellar envelopes. The turbulent velocities of V turb sime 12-13 km s-1 observed in the [Fe II] a 4 F forbidden lines are found to be a common property of our sample, and are less than that derived from the hotter chromospheric C II] 2325 Å lines observed in α Ori, where V turb sime 17-19 km s-1. For the first time, we have dynamically resolved the motions of the dominant cool atmospheric component discovered in α Ori from multiwavelength radio interferometry by Lim et al. Surprisingly, the emission centroids are quite Gaussian and at rest with respect to the M supergiants. These constraints combined with model calculations of the infrared emission line fluxes for α Ori imply that the warm material has a low outflow velocity and is located close to the star. We have also detected narrow [Fe I] 24.04 μm emission that confirms Fe II is the dominant ionization state in α Ori's extended atmosphere.

The Impact of a Ligand Binding on Strand Migration in the SAM-I Riboswitch

PubMed Central

Huang, Wei; Kim, Joohyun; Jha, Shantenu; Aboul-ela, Fareed

2013-01-01

Riboswitches sense cellular concentrations of small molecules and use this information to adjust synthesis rates of related metabolites. Riboswitches include an aptamer domain to detect the ligand and an expression platform to control gene expression. Previous structural studies of riboswitches largely focused on aptamers, truncating the expression domain to suppress conformational switching. To link ligand/aptamer binding to conformational switching, we constructed models of an S-adenosyl methionine (SAM)-I riboswitch RNA segment incorporating elements of the expression platform, allowing formation of an antiterminator (AT) helix. Using Anton, a computer specially developed for long timescale Molecular Dynamics (MD), we simulated an extended (three microseconds) MD trajectory with SAM bound to a modeled riboswitch RNA segment. Remarkably, we observed a strand migration, converting three base pairs from an antiterminator (AT) helix, characteristic of the transcription ON state, to a P1 helix, characteristic of the OFF state. This conformational switching towards the OFF state is observed only in the presence of SAM. Among seven extended trajectories with three starting structures, the presence of SAM enhances the trend towards the OFF state for two out of three starting structures tested. Our simulation provides a visual demonstration of how a small molecule (<500 MW) binding to a limited surface can trigger a large scale conformational rearrangement in a 40 kDa RNA by perturbing the Free Energy Landscape. Such a mechanism can explain minimal requirements for SAM binding and transcription termination for SAM-I riboswitches previously reported experimentally. PMID:23704854

New Measurement of Singly Ionized Selenium Spectra by High Resolution Fourier Transform and Grating Spectroscopy

NASA Astrophysics Data System (ADS)

Hala, Noman; Nave, G.; Kramida, A.; Ahmad, T.; Nahar, S.; Pradhan, A.

2015-05-01

We report new measurements of singly ionised selenium, an element of the iron group detected in nearly twice as many planetary nebulae as any other trans-iron element. We use the NIST 2 m UV/Vis/IR and FT700 UV/Vis Fourier transform spectrometers over the wavelength range of 2000 Å-2.5 μm, supplemented in the lower wavelength region 300-2400 Å with grating spectra taken on a 3-m normal incidence vacuum spectrograph. The analysis of Se II is being extended, covering the wide spectral region from UV to IR. From our investigation, we found serious inconsistency and incompleteness in the previously published results, where several levels were reported without any designation. The analysis is being revised and extended with the help of semiempirical quasi-relativistic Hartree-Fock calculations, starting with the 4s24p3- [4s24p2(4d +5d +5s +6s) +4s4p4] transition array. Out of fifty-two previously reported levels, we rejected thirteen and found several new level values. With the new measurements, we expect to observe transitions between 4s24p2(4d +5s) and 4s24p2(5p +4f), lying in the visible and IR region. A complete interpretation of the level system of both parities will be assisted by least squares fitted parametric calculations. In all, we have already classified about 450 observed lines involving 89 energy levels.

Imaging the Mount St. Helens Magmatic Systems using Magnetotellurics

NASA Astrophysics Data System (ADS)

Hill, G. J.; Caldwell, T. G.; Heise, W.; Bibby, H. M.; Chertkoff, D. G.; Burgess, M. K.; Cull, J. P.; Cas, R. A.

2009-05-01

A detailed magnetotelluric survey of Mount St. Helens shows that a conduit like zone of high electrical conductivity beneath the volcano is connected to a larger zone of high conductivity at 15 km depth that extends eastward to Mount Adams. We interpret this zone to be a region of connected melt that acts as the reservoir for the silicic magma being extruded at the time of the magnetotelluric survey. This interpretation is consistent with a mid-crustal origin for the silicic component of the Mount St. Helens' magmas and provides an elegant explanation for a previously unexplained feature of the seismicity observed at the time of the catastrophic eruption in 1980. This zone of high mid-crustal conductivity extends northwards to near Mount Rainier suggesting a single region of connected melt comparable in size to the largest silicic volcanic systems known.

Prediction and assimilation of surf-zone processes using a Bayesian network: Part II: Inverse models

USGS Publications Warehouse

Plant, Nathaniel G.; Holland, K. Todd

2011-01-01

A Bayesian network model has been developed to simulate a relatively simple problem of wave propagation in the surf zone (detailed in Part I). Here, we demonstrate that this Bayesian model can provide both inverse modeling and data-assimilation solutions for predicting offshore wave heights and depth estimates given limited wave-height and depth information from an onshore location. The inverse method is extended to allow data assimilation using observational inputs that are not compatible with deterministic solutions of the problem. These inputs include sand bar positions (instead of bathymetry) and estimates of the intensity of wave breaking (instead of wave-height observations). Our results indicate that wave breaking information is essential to reduce prediction errors. In many practical situations, this information could be provided from a shore-based observer or from remote-sensing systems. We show that various combinations of the assimilated inputs significantly reduce the uncertainty in the estimates of water depths and wave heights in the model domain. Application of the Bayesian network model to new field data demonstrated significant predictive skill (R2 = 0.7) for the inverse estimate of a month-long time series of offshore wave heights. The Bayesian inverse results include uncertainty estimates that were shown to be most accurate when given uncertainty in the inputs (e.g., depth and tuning parameters). Furthermore, the inverse modeling was extended to directly estimate tuning parameters associated with the underlying wave-process model. The inverse estimates of the model parameters not only showed an offshore wave height dependence consistent with results of previous studies but the uncertainty estimates of the tuning parameters also explain previously reported variations in the model parameters.

[A NASA / University Joint Venture in Space Science

NASA Technical Reports Server (NTRS)

Wold, Donald C.

1996-01-01

MILAGRO is a water-Cherenkov detector for observing cosmic gamma rays over a broad energy range of 100 GeV to 100 TeV. MILAGRO will be the first detector that has sensitivity overlapping both air-Cherenkov and air-shower detectors. With this detector scientists in the collaboration will study previously observed celestial sources at their known emission energies, extend these observations into a new energy regime, and search for new sources at unexplored energies. The diffuse gamma-radiation component in our galaxy, which originates from interactions of cosmic rays with interstellar gas and photons, provides important information about the density, distribution, and spectrum of the cosmic rays that pervade the interstellar medium. Events in the Compton Gamma Ray Observatory (GRO) are being observed up to about 30 GeV, differing by slightly more than order of magnitude from the low energy threshold of MILAGRO. By looking in coincidence at sources, correlated observations will greatly extend the astrophysics potential of MILAGRO and NASA's GRO. A survey of cosmic-ray observatories is being prepared for scientists and others to provide a resource and reference which describes high energy cosmic-ray research activities around the world. This summary presents information about each research group, such as names of principal investigators, number of persons in the collaboration, energy range, sensitivity, angular resolution, and surface area of detector. Similarly, a survey of gamma-ray telescopes is being prepared to provide a resource and reference which describes gamma-ray telescopes for investigating galactic diffuse gamma-ray flux currently observed in the GeV energy range, but is expected to extend into the TeV range. Two undergraduate students are compiling information about gamma-ray telescopes and high energy cosmic-ray observatories for these surveys. Funding for this project was provided by the Arkansas Space Grant Consortium. Also enclosed Appendix A, B, C, D and E.

Magnetic Roots and the Driving of Extended Coronal Heating

NASA Technical Reports Server (NTRS)

Porter, Jason G.; Falconer, D. A.; Moore, Ronald L.; Harvey, Karen L.; Rabin, Douglas M.; Shimizu, T.

1998-01-01

We report results from a continuation of a previous study, in which we found large bright coronal loops within active regions and extending from active regions that have one end rooted near an island of included magnetic polarity that is a site of enhanced coronal heating and microflares. This suggested that magnetic activity such as microflaring results in enhanced heating in both the compact core field around the island and in the large loops extending from it. We might expect that the intensity variations due to enhanced heating in the compact and extended structures would be correlated. However, although some ex- tended loops do respond to the largest events taking place in the core fields near their feet, they do not show a clear response to most smaller individual events nor to the overall envelope of coronal heating activity in the core fields at their feet as determined from longer-term observations. Thus, while it is clear that the extended loops' heating is being driven from their ends at the magnetic islands, much of this heating is apparently by some form of footpoint activity that is not strongly coupled to the heating in the footpoint core fields. One possibility is that the remote heating in the extended loops is driven by reconnection at the magnetic null over the island, and that this reconnection is driven mainly by core-field activity that produces little coronal heating within the core field itself, perhaps in the manner of the numerical simulations by Karpen, Antiochos, and DeVore.

Curvature Constraints from the Causal Entropic Principle

NASA Astrophysics Data System (ADS)

Bozek, Brandon

2010-01-01

Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The Causal Entropic Principle (Bousso, et al.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the Causal Entropic Principle to predict the preferred curvature within the "multiverse." We have found that values larger than ρk = 40*ρm are disfavored by more than 99.99% and a peak value at ρΛ = 7.9*10-123 and ρk =4.3*ρm for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending on the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.

Curvature constraints from the causal entropic principle

NASA Astrophysics Data System (ADS)

Bozek, Brandon; Albrecht, Andreas; Phillips, Daniel

2009-07-01

Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The causal entropic principle (Bousso et al.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the causal entropic principle to predict the preferred curvature within the “multiverse.” We have found that values larger than ρk=40ρm are disfavored by more than 99.99% peak value at ρΛ=7.9×10-123 and ρk=4.3ρm for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending on the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.

Curvature constraints from the causal entropic principle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bozek, Brandon; Albrecht, Andreas; Phillips, Daniel

2009-07-15

Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The causal entropic principle (Bousso et al.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the causal entropic principle to predict the preferred curvature within the 'multiverse'. We have found that values larger than {rho}{sub k}=40{rho}{sub m} are disfavored by more than 99.99% peak value at {rho}{sub {lambda}}=7.9x10{sup -123} and {rho}{sub k}=4.3{rho}{sub m}more » for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending on the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.« less

A compact dual band MIMO PIFA for 5G applications

NASA Astrophysics Data System (ADS)

Rachakonda, A.; Bang, P.; Mudiganti, J.

2017-11-01

5G applications support operations in 28, 37, 60 and 73GHz bands and is expected to support 1GHz bandwidth. In the present paper, planar inverted F antenna for 28GHz operation has been proposed for 5G applications for which a return loss of -17.46dB and a gain of 9.30dB have been observed. In addition, the design has been extended for dual band operation at 28 and 37GHz by implementing an L slot in the patch. An excellent return loss of -32.54dB and -18.57dB with a gain of 8.62dB has been observed. Moreover, a feasible bandwidth of 1.02GHz has been obtained in former design, while an enhanced bandwidth of 1.3GHz has been obtained at both bands in case of latter design. However, for better gain & data rate considerations, the previous design has been extended as a MIMO configuration with 2 antenna elements (2x1) and corresponding performance parameters have been evaluated.

Human machine interaction via the transfer of power and information signals

NASA Technical Reports Server (NTRS)

Kazerooni, H.; Foslien, W. K.; Anderson, B. J.; Hessburg, T. M.

1989-01-01

Robot manipulators are designed to perform tasks which would otherwise be executed by a human operator. No manipulator can even approach the speed and accuracy with which humans execute these tasks. But manipulators have the capability to exceed human ability in one particular area: strength. Through any reasonable observation and experience, the human's ability to perform a variety of physical tasks is limited not by his intelligence, but by his physical strength. If, in the appropriate environment, we can more closely integrate the mechanical power of a machine with intellectually driven human hand under the supervisory control of the human's intellect, we will then have a system which is superior to a loosely-integrated combination of a human and his fully automated robot as in the present day robotic systems. We must therefore develop a fundamental approach to the problem of this extending human mechanical power in certain environments. Extenders will be a class of robots worn by humans to increase human mechanical ability, while the wearer's intellect remains the central intelligent control system for manipulating the extender. The human body, in physical contact with the extender, exchanges information signals and power with the extender. Commands are transferred to the extender via the contact forces between the wearer and the extender as opposed to use of joystick (master arm), push-button or key-board to execute such commands that were used in previous man amplifiers. Instead, the operator becomes an integral part of the extender while executing the task. In this unique configuration the mechanical power transfer between the human and extender occurs in addition to information signal transfer. When the wearer uses the extender to touch and manipulate an object, the extender transfers to the wearer's hand, in feedback fashion, a scaled-down value of the actual external load which the extender is manipulating. This natural feedback force on the wearer's hand allows him to feel the scaled-down value of the external forces in the manipulations. Extenders can be utilized to maneuver very heavy loads in factories, shipyards, airports, and construction sites. In some instances, for example, extenders can replace forklifts. The experimental results for a prototype extender are discussed.

Conformation study of HA(306-318) antigenic peptide of the haemagglutinin influenza virus protein

NASA Astrophysics Data System (ADS)

Bertrand, A.; Brito, R. M.; Alix, A. J. P.; Lancelin, J. M.; Carvalho, R. A.; Geraldes, C. F. G. C.; Lakhdar-Ghazal, F.

2006-11-01

Several HLA-DR alleles present the immunodominant HA(306-318) peptide of haemagglutinin of the influenza virus to T cells. NMR data of the peptide in various water solutions exclude any α-helix or turn conformations. Circular dichroism and Fourier transform infrared spectroscopies indicate an estimated β-extended structure in water of 31% and 28%, respectively, with spectra shape similar to the ones observed for β-sheet containing proteins. The H/D amide exchange suggests a stable length-dependent interchain hydrogen-bonding. The partially β-extended conformation of HA(306-318) in solution might be close to the one found in HA(306-318)-HLA-DR1 complex. These results suggest different interconverting extended conformations of HA(306-318), depending on the microenvironment of the solution medium. This flexibility emphasizes the ability of some peptides to fit more easily the binding site of several HLA-DR molecules. Similar results were obtained on the HIV P25(263-277) peptide which has been previously shown to be a good DR1 binder. From a vibrational point of view, infrared Amide I frequencies of secondary structures in peptides were ascertained. As previously demonstrated for proteins in solution, Fourier transform infrared and circular dichroism spectroscopies appear to be valuable tools for conformational properties of peptides. Their use may contribute to the detection of peptide conformation-binding relationship which has to be further tested by biochemical and biological studies.

High-resolution, far-infrared observations of NGC 2071

NASA Technical Reports Server (NTRS)

Butner, Harold M.; Evans, Neal J., II; Harvey, Paul M.; Mundy, Lee G.; Natta, Antonella

1990-01-01

The far-IR emission of the visible reflection nebula NGC 2071 has been resolved at both 50 and 100 microns along several directions. The observations reveal an extended, roughly spherical source with an average source diameter of about 12 arcsec or 4700 AU at 50 microns and about 16 arcsec or 6200 AU at 100 microns. The source is modeled using a radiative transport code to match scans of the source and previous photometry. The luminosity of the source is 520 solar at a distance of 390 pc. The optical depth at 100 microns is 0.20, implying a mass of 1.2-10 solar within a radius of 5900 AU. The density gradient is in good agreement with theoretical models for infalling envelopes around protostars and in reasonable agreement with other observational determinations.

Comparing sugar type supplementation for cryopreservation of boar semen in egg yolk based extender.

PubMed

Malo, C; Gil, L; Gonzalez, N; Cano, R; de Blas, I; Espinosa, E

2010-08-01

Cryopreservation of boar semen is still considered suboptimal due to lower fertility when compared to fresh semen. The aim of this study was to evaluate the effects of the addition of different sugars (lactose, trehalose and glucose) on boar spermatozoa cryopreserved in an egg yolk based extender. Ejaculates were collected from a boar previously selected and semen samples were processed using the straw freezing procedure. In experiment 1, subsamples of semen were frozen in three different extenders: recommended lactose egg yolk extender (LEY); trehalose egg yolk extender (TEY) and glucose egg yolk extender (GEY). Sperm quality was assessed for motility, viability, acrosome integrity and hypoosmotic swelling test response upon collection, after freezing and thawing and then every hour for 3h. Results showed that total motility at 1 and 3h, progressive motility at 3h, positive hypoosmotic response at 2 and 3h and acrosome integrity at all times were significantly improved when trehalose was added to the extender. In experiment 2, sugar influence was also demonstrated in vitro fertilization. A total of 1691 oocytes were in vitro matured and inseminated with frozen-thawed sperm at 2000:1 sperm:oocyte ratio and coincubated for 6h. Presumptive zygotes were cultured in NCSU-23 medium to assess fertilization parameters and embryo development. Both penetration and monospermy rates were significantly higher for trehalose frozen semen. A significant increase was observed in efficiency and blastocyst formation rates from TEY to the other groups. Our results demonstrated that trehalose extender enhances spermatozoa viability and its in vitro fertilization parameters in boar ejaculates with good sperm freezability. Further studies are necessary to assess the impact of sugars on the entire population. (c) 2010 Elsevier Inc. All rights reserved.

Hydrodynamic and Chemical Factors in Clogging by Montmorillonite in Porous Media

PubMed Central

Mays, David C.; Hunt, James R.

2008-01-01

Clogging by colloid deposits is important in water treatment filters, groundwater aquifers, and petroleum reservoirs. The complexity of colloid deposition and deposit morphology preclude models based on first principles, so this study extends an empirical approach to quantify clogging using a simple, one-parameter model. Experiments were conducted with destabilized suspensions of sodium- and calcium-montmorillonite to quantify the hydrodynamic and chemical factors important in clogging. Greater clogging is observed at slower fluid velocity, consistent with previous investigations. However, calcium-montmorillonite causes one order of magnitude less clogging per mass of deposited particles compared to sodium-montmorillonite or a previously published summary of clogging in model granular media. Steady state conditions, in which the permeability and the quantity of deposited material are both constant, were not observed, even though the experimental conditions were optimized for that purpose. These results indicate that hydrodynamic aspects of clogging by these natural materials are consistent with those of simplified model systems, and they demonstrate significant chemical effects on clogging for fully destabilized montmorillonite clay. PMID:17874771

On the Absence of Non-thermal X-Ray Emission around Runaway O Stars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toalá, J. A.; Oskinova, L. M.; Ignace, R.

Theoretical models predict that the compressed interstellar medium around runaway O stars can produce high-energy non-thermal diffuse emission, in particular, non-thermal X-ray and γ -ray emission. So far, detection of non-thermal X-ray emission was claimed for only one runaway star, AE Aur. We present a search for non-thermal diffuse X-ray emission from bow shocks using archived XMM-Newton observations for a clean sample of six well-determined runaway O stars. We find that none of these objects present diffuse X-ray emission associated with their bow shocks, similarly to previous X-ray studies toward ζ Oph and BD+43°3654. We carefully investigated multi-wavelength observations ofmore » AE Aur and could not confirm previous findings of non-thermal X-rays. We conclude that so far there is no clear evidence of non-thermal extended emission in bow shocks around runaway O stars.« less

Hydrodynamic and chemical factors in clogging by montmorillonite in porous media.

PubMed

Mays, David C; Hunt, James R

2007-08-15

Clogging by colloid deposits is important in water treatment filters, groundwater aquifers, and petroleum reservoirs. The complexity of colloid deposition and deposit morphology preclude models based on first principles, so this study extends an empirical approach to quantify clogging using a simple, one-parameter model. Experiments were conducted with destabilized suspensions of sodium- and calcium-montmorillonite to quantify the hydrodynamic and chemical factors important in clogging. Greater clogging is observed at slower fluid velocity, consistent with previous investigations. However, calcium-montmorillonite causes 1 order of magnitude less clogging per mass of deposited particles compared to sodium-montmorillonite or a previously published summary of clogging in model granular media. Steady-state conditions, in which the permeability and the quantity of deposited material are both constant, were not observed, even though the experimental conditions were optimized for that purpose. These results indicate that hydrodynamic aspects of clogging by these natural materials are consistent with those of simplified model systems, and they demonstrate significant chemical effects on clogging for fully destabilized montmorillonite clay.

Levels in 227Ac populated in the 230Th( p, α) reaction

NASA Astrophysics Data System (ADS)

Burke, D. G.; Garrett, P. E.; Qu, Tao

2003-09-01

The 230,232Th(p, α) 227,229Ac reactions were studied using 20 MeV protons and a magnetic spectrograph to analyze the reaction products. Relative populations of levels in 229Ac correlated well with previously published (t, α) results for the same final levels, showing that the similarity of the two reactions observed empirically in the deformed rare earth region extends to actinides. The most strongly populated level in 227Ac is at 639 keV, and is assigned as the 1/2 +[4 0 0] bandhead. The 435 keV level, previously adopted as the 1/2 +[6 6 0] bandhead, also has a significant intensity that is attributed to Δ N=2 mixing between these two K=1/2 proton orbitals. The Δ N=2 matrix element estimated from these data is ˜80 keV, similar to values observed for the same two Nilsson states as neutron orbitals in the dysprosium isotopes.

A daily Azores-Iceland North Atlantic Oscillation index back to 1850.

PubMed

Cropper, Thomas; Hanna, Edward; Valente, Maria Antónia; Jónsson, Trausti

2015-07-01

We present the construction of a continuous, daily (09:00 UTC), station-based (Azores-Iceland) North Atlantic Oscillation (NAO) Index back to 1871 which is extended back to 1850 with additional daily mean data. The constructed index more than doubles the length of previously existing, widely available, daily NAO time series. The index is created using entirely observational sea-level pressure (SLP) data from Iceland and 73.5% of observational SLP data from the Azores - the remainder being filled in via reanalysis (Twentieth Century Reanalysis Project and European Mean Sea Level Pressure) SLP data. Icelandic data are taken from the Southwest Iceland pressure series. We construct and document a new Ponta Delgada SLP time series based on recently digitized and newly available data that extend back to 1872. The Ponta Delgada time series is created by splicing together several fractured records (from Ponta Delgada, Lajes, and Santa Maria) and filling in the major gaps (pre-1872, 1888-1905, and 1940-1941) and occasional days (145) with reanalysis data. Further homogeneity corrections are applied to the Azores record, and the daily (09:00 UTC) NAO index is then calculated. The resulting index, with its extended temporal length and daily resolution, is the first reconstruction of daily NAO back into the 19th Century and therefore is useful for researchers across multiple disciplines.

A Suzaku, NuSTAR and XMMNewton} view on variable absorption and relativistic reflection in NGC 4151

NASA Astrophysics Data System (ADS)

Beuchert, T.; Markowitz, A.; Dauser, T.; Garcia, J.; Keck, M.; Wilms, J.; Kadler, M.; Brenneman, L.; Zdziarski, A.

2017-10-01

We disentangle X-ray disk reflection from complex line-of-sight absorption in NGC 4151 using Suzaku, NuSTAR, and XMMNewton}. Extending upon Keck et al. (2015), we develop a physically-motivated baseline model using the latest lamp-post reflection code relxillCp_lp, which includes a Comptonization continuum. We identify two components at heights of 1.2 and 15.0 gravitational radii using a long-look simultaneous Suzaku/NuSTAR observation but argue for a vertically extended corona as opposed to distinct primary sources. We also find two neutral absorbers (one full-covering and one partial-covering), an ionized absorber (log ξ=2.8), and a highly-ionized ultra-fast outflow, all reported previously. All analyzed spectra are well described by this baseline model. The bulk of the spectral variability on time-scales from days to years can be attributed to changes of both neutral absorbers, which are inversely correlated with the hard X-ray continuum flux. The observed evolution is either consistent with changes in the absorber structure (clumpy absorber in the outer BLR or a dusty radiatively driven wind) or a geometrically stable neutral absorber that becomes increasingly ionized at a rising flux level. The soft X-rays below 1 keV are dominated by photoionized emission from extended gas, which may act as a warm mirror for the nuclear radiation.

Decrease in glutathione content in boar sperm after cryopreservation. Effect of the addition of reduced glutathione to the freezing and thawing extenders.

PubMed

Gadea, Joaquín; Sellés, Elena; Marco, Marco Antonio; Coy, Pilar; Matás, Carmen; Romar, Raquel; Ruiz, Salvador

2004-08-01

Although glutathione content in boar spermatozoa has been previously reported, the effect of reduced glutathione (GSH) on semen parameters and the fertilizing ability of boar spermatozoa after cryopreservation has never been evaluated. In this study, GSH content was determined in ejaculated boar spermatozoa before and after cryopreservation. Semen samples were centrifuged and GSH content in the resulting pellet monitored spectrophotometrically. The fertilizing ability of frozen-thawed boar sperm was also tested in vitro by incubating sperm with in vitro matured oocytes obtained from gilts. GSH content in fresh semen was 3.84 +/- 0.21 nM GSH/10(8) sperm. Following semen cryopreservation, there was a 32% decrease in GSH content (P < 0.0001). There were significant differences in sperm GSH content between different boars and after various preservation protocols (P = 0.0102 ). The effect of addition of GSH to the freezing and thawing extenders was also evaluated. Addition of 5 mM GSH to the freezing extender did not have a significant effect on standard semen parameters or sperm fertilizing ability after thawing. In contrast, when GSH was added to the thawing extender, a dose-dependent tendency to increase in sperm fertilizing ability was observed, although no differences were observed in standard semen parameters. In summary, (i) there was a loss in GSH content after cryopreservation of boar semen; (ii) addition of GSH to the freezing extender did not result in any improvement in either standard semen parameters or sperm fertilizing ability; and (iii) addition of GSH to the thawing extender resulted in a significant increase in sperm fertilizing ability. Nevertheless, future studies must conclude if this is the case for all boars. Furthermore, since addition of GSH to the thawing extender did not result in an improvement in standard semen parameters, this suggests that during the thawing process, GSH prevents damage of a sperm property that is critical in the fertilization process but that is not measured in the routine semen analysis.

Expanding the clinical and genetic spectra of NKX6-2-related disorder.

PubMed

Baldi, C; Bertoli-Avella, A M; Al-Sannaa, N; Alfadhel, M; Al-Thihli, K; Alameer, S; Elmonairy, A A; Al Shamsi, A M; Abdelrahman, H A; Al-Gazali, L; Shawli, A; Al-Hakami, F; Yavuz, H; Kandaswamy, K K; Rolfs, A; Brandau, O; Bauer, P

2018-05-01

Hypomyelinating leukodystrophies (HLDs) affect the white matter of the central nervous system and manifest as neurological disorders. They are genetically heterogeneous. Very recently, biallelic variants in NKX6-2 have been suggested to cause a novel form of autosomal recessive HLD. Using whole-exome or whole-genome sequencing, we identified the previously reported c.196delC and c.487C>G variants in NKX6-2 in 3 and 2 unrelated index cases, respectively; the novel c.608G>A variant was identified in a sixth patient. All variants were homozygous in affected family members only. Our patients share a primary diagnosis of psychomotor delay, and they show spastic quadriparesis, nystagmus and hypotonia. Seizures and dysmorphic features (observed in 2 families each) represent an addition to the phenotype, while developmental regression (observed in 3 families) appears to be a notable and previously underestimated clinical feature. Our findings extend the clinical and mutational spectra associated with this novel form of HLD. Comparative analysis of our 10 patients and the 15 reported previously did, however, not reveal clear evidence for a genotype-phenotype correlation. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Complete anatomy of {overline B_d} to {overline {text{K}}^{{*0}}} (→ Kπ) ℓ + ℓ - and its angular distribution

NASA Astrophysics Data System (ADS)

Matias, J.; Mescia, F.; Ramon, M.; Virto, J.

2012-04-01

We present a complete and optimal set of observables for the exclusive 4-body overline B meson decay {overline B_d} to {overline {text{K}}^{{*0}}} (→ Kπ) ℓ + ℓ -in the low dilepton mass region, that contains a maximal number of clean observables. This basis of observables is built in a systematic way. We show that all the previously defined observables and any observable that one can construct, can be expressed as a function of this basis. This set of observables contains all the information that can be extracted from the angular distribution in the cleanest possible way. We provide explicit expressions for the full and the uniangular distributions in terms of this basis. The conclusions presented here can be easily extended to the large- q 2 region. We study the sensitivity of the observables to right-handed currents and scalars. Finally, we present for the first time all the symmetries of the full distribution including massive terms and scalar contributions.

Investigating the TeV Morphology of MGRO J1908+06 with VERITAS

NASA Astrophysics Data System (ADS)

Aliu, E.; Archambault, S.; Aune, T.; Behera, B.; Beilicke, M.; Benbow, W.; Berger, K.; Bird, R.; Buckley, J. H.; Bugaev, V.; Cardenzana, J. V.; Cerruti, M.; Chen, X.; Ciupik, L.; Collins-Hughes, E.; Connolly, M. P.; Cui, W.; Dumm, J.; Dwarkadas, V. V.; Errando, M.; Falcone, A.; Federici, S.; Feng, Q.; Finley, J. P.; Fleischhack, H.; Fortin, P.; Fortson, L.; Furniss, A.; Galante, N.; Gall, D.; Gillanders, G. H.; Griffin, S.; Griffiths, S. T.; Grube, J.; Gyuk, G.; Hanna, D.; Holder, J.; Hughes, G.; Humensky, T. B.; Kaaret, P.; Kertzman, M.; Khassen, Y.; Kieda, D.; Krennrich, F.; Kumar, S.; Lang, M. J.; Madhavan, A. S.; Maier, G.; McCann, A. J.; Meagher, K.; Millis, J.; Moriarty, P.; Mukherjee, R.; Nieto, D.; O'Faoláin de Bhróithe, A.; Ong, R. A.; Otte, A. N.; Pandel, D.; Park, N.; Pohl, M.; Popkow, A.; Prokoph, H.; Quinn, J.; Ragan, K.; Rajotte, J.; Ratliff, G.; Reyes, L. C.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Rousselle, J.; Sembroski, G. H.; Shahinyan, K.; Sheidaei, F.; Smith, A. W.; Staszak, D.; Telezhinsky, I.; Tsurusaki, K.; Tucci, J. V.; Tyler, J.; Varlotta, A.; Vassiliev, V. V.; Vincent, S.; Wakely, S. P.; Ward, J. E.; Weinstein, A.; Welsing, R.; Wilhelm, A.

2014-06-01

We report on deep observations of the extended TeV gamma-ray source MGRO J1908+06 made with the VERITAS very high energy gamma-ray observatory. Previously, the TeV emission has been attributed to the pulsar wind nebula (PWN) of the Fermi-LAT pulsar PSR J1907+0602. We detect MGRO J1908+06 at a significance level of 14 standard deviations (14σ) and measure a photon index of 2.20 ± 0.10stat ± 0.20sys. The TeV emission is extended, covering the region near PSR J1907+0602 and also extending toward SNR G40.5-0.5. When fitted with a two-dimensional Gaussian, the intrinsic extension has a standard deviation of σsrc = 0.°44 ± 0.°02. In contrast to other TeV PWNe of similar age in which the TeV spectrum softens with distance from the pulsar, the TeV spectrum measured near the pulsar location is consistent with that measured at a position near the rim of G40.5-0.5, 0.°33 away.

An X-Ray Atlas of Groups of Galaxies

NASA Technical Reports Server (NTRS)

Mulchaey, John S.; Davis, David S.; Mushotzky, Richard F.; Burnstein, David

2003-01-01

A search was conducted for a hot intragroup medium in 10(exp 9) low-redshift galaxy groups observed with the ROSAT PSPC. Evidence for diffuse, extended X-ray emission is found in at least 61 groups. Approximately one-third of these detections have not been previously reported in the literature. Most of the groups are detected out to less than half of the virial radius with ROSAT. Although some spiral-rich groups do contain an intragroup medium, diffuse emission is restricted to groups that contain at least one early-type galaxy.

Hybrid Discrete-Continuous Markov Decision Processes

NASA Technical Reports Server (NTRS)

Feng, Zhengzhu; Dearden, Richard; Meuleau, Nicholas; Washington, Rich

2003-01-01

This paper proposes a Markov decision process (MDP) model that features both discrete and continuous state variables. We extend previous work by Boyan and Littman on the mono-dimensional time-dependent MDP to multiple dimensions. We present the principle of lazy discretization, and piecewise constant and linear approximations of the model. Having to deal with several continuous dimensions raises several new problems that require new solutions. In the (piecewise) linear case, we use techniques from partially- observable MDPs (POMDPS) to represent value functions as sets of linear functions attached to different partitions of the state space.

High statistics measurement of the positron fraction in primary cosmic rays of 0.5-500 GeV with the alpha magnetic spectrometer on the international space station.

PubMed

Accardo, L; Aguilar, M; Aisa, D; Alpat, B; Alvino, A; Ambrosi, G; Andeen, K; Arruda, L; Attig, N; Azzarello, P; Bachlechner, A; Barao, F; Barrau, A; Barrin, L; Bartoloni, A; Basara, L; Battarbee, M; Battiston, R; Bazo, J; Becker, U; Behlmann, M; Beischer, B; Berdugo, J; Bertucci, B; Bigongiari, G; Bindi, V; Bizzaglia, S; Bizzarri, M; Boella, G; de Boer, W; Bollweg, K; Bonnivard, V; Borgia, B; Borsini, S; Boschini, M J; Bourquin, M; Burger, J; Cadoux, F; Cai, X D; Capell, M; Caroff, S; Carosi, G; Casaus, J; Cascioli, V; Castellini, G; Cernuda, I; Cerreta, D; Cervelli, F; Chae, M J; Chang, Y H; Chen, A I; Chen, H; Cheng, G M; Chen, H S; Cheng, L; Chikanian, A; Chou, H Y; Choumilov, E; Choutko, V; Chung, C H; Cindolo, F; Clark, C; Clavero, R; Coignet, G; Consolandi, C; Contin, A; Corti, C; Coste, B; Cui, Z; Dai, M; Delgado, C; Della Torre, S; Demirköz, M B; Derome, L; Di Falco, S; Di Masso, L; Dimiccoli, F; Díaz, C; von Doetinchem, P; Du, W J; Duranti, M; D'Urso, D; Eline, A; Eppling, F J; Eronen, T; Fan, Y Y; Farnesini, L; Feng, J; Fiandrini, E; Fiasson, A; Finch, E; Fisher, P; Galaktionov, Y; Gallucci, G; García, B; García-López, R; Gast, H; Gebauer, I; Gervasi, M; Ghelfi, A; Gillard, W; Giovacchini, F; Goglov, P; Gong, J; Goy, C; Grabski, V; Grandi, D; Graziani, M; Guandalini, C; Guerri, I; Guo, K H; Haas, D; Habiby, M; Haino, S; Han, K C; He, Z H; Heil, M; Henning, R; Hoffman, J; Hsieh, T H; Huang, Z C; Huh, C; Incagli, M; Ionica, M; Jang, W Y; Jinchi, H; Kanishev, K; Kim, G N; Kim, K S; Kirn, Th; Kossakowski, R; Kounina, O; Kounine, A; Koutsenko, V; Krafczyk, M S; Kunz, S; La Vacca, G; Laudi, E; Laurenti, G; Lazzizzera, I; Lebedev, A; Lee, H T; Lee, S C; Leluc, C; Levi, G; Li, H L; Li, J Q; Li, Q; Li, Q; Li, T X; Li, W; Li, Y; Li, Z H; Li, Z Y; Lim, S; Lin, C H; Lipari, P; Lippert, T; Liu, D; Liu, H; Lolli, M; Lomtadze, T; Lu, M J; Lu, Y S; Luebelsmeyer, K; Luo, F; Luo, J Z; Lv, S S; Majka, R; Malinin, A; Mañá, C; Marín, J; Martin, T; Martínez, G; Masi, N; Massera, F; Maurin, D; Menchaca-Rocha, A; Meng, Q; Mo, D C; Monreal, B; Morescalchi, L; Mott, P; Müller, M; Ni, J Q; Nikonov, N; Nozzoli, F; Nunes, P; Obermeier, A; Oliva, A; Orcinha, M; Palmonari, F; Palomares, C; Paniccia, M; Papi, A; Pauluzzi, M; Pedreschi, E; Pensotti, S; Pereira, R; Pilastrini, R; Pilo, F; Piluso, A; Pizzolotto, C; Plyaskin, V; Pohl, M; Poireau, V; Postaci, E; Putze, A; Quadrani, L; Qi, X M; Rancoita, P G; Rapin, D; Ricol, J S; Rodríguez, I; Rosier-Lees, S; Rossi, L; Rozhkov, A; Rozza, D; Rybka, G; Sagdeev, R; Sandweiss, J; Saouter, P; Sbarra, C; Schael, S; Schmidt, S M; Schuckardt, D; Schulz von Dratzig, A; Schwering, G; Scolieri, G; Seo, E S; Shan, B S; Shan, Y H; Shi, J Y; Shi, X Y; Shi, Y M; Siedenburg, T; Son, D; Spada, F; Spinella, F; Sun, W; Sun, W H; Tacconi, M; Tang, C P; Tang, X W; Tang, Z C; Tao, L; Tescaro, D; Ting, Samuel C C; Ting, S M; Tomassetti, N; Torsti, J; Türkoğlu, C; Urban, T; Vagelli, V; Valente, E; Vannini, C; Valtonen, E; Vaurynovich, S; Vecchi, M; Velasco, M; Vialle, J P; Vitale, V; Volpini, G; Wang, L Q; Wang, Q L; Wang, R S; Wang, X; Wang, Z X; Weng, Z L; Whitman, K; Wienkenhöver, J; Wu, H; Wu, K Y; Xia, X; Xie, M; Xie, S; Xiong, R Q; Xin, G M; Xu, N S; Xu, W; Yan, Q; Yang, J; Yang, M; Ye, Q H; Yi, H; Yu, Y J; Yu, Z Q; Zeissler, S; Zhang, J H; Zhang, M T; Zhang, X B; Zhang, Z; Zheng, Z M; Zhou, F; Zhuang, H L; Zhukov, V; Zichichi, A; Zimmermann, N; Zuccon, P; Zurbach, C

2014-09-19

A precision measurement by AMS of the positron fraction in primary cosmic rays in the energy range from 0.5 to 500 GeV based on 10.9 million positron and electron events is presented. This measurement extends the energy range of our previous observation and increases its precision. The new results show, for the first time, that above ∼200  GeV the positron fraction no longer exhibits an increase with energy.

Residual entanglement of accelerated fermions is not nonlocal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friis, Nicolai; Koehler, Philipp; Bertlmann, Reinhold A.

2011-12-15

We analyze the operational meaning of the residual entanglement in noninertial fermionic systems in terms of the achievable violation of the Clauser-Horne-Shimony-Holt (CHSH) inequality. We demonstrate that the quantum correlations of fermions, which were previously found to survive in the infinite acceleration limit, cannot be considered to be nonlocal. The entanglement shared by an inertial and an accelerated observer cannot be utilized for the violation of the CHSH inequality in case of high accelerations. Our results are shown to extend beyond the single-mode approximation commonly used in the literature.

Progress of Rugby Hohlraum Experiments on Omega

NASA Astrophysics Data System (ADS)

Philippe, Franck; Tassin, Veronique; Casner, Alexis; Gauthier, Pascal; Seytor, Patricia; Monteil, Marie-Christine; Park, Hye-Sook; Robey, Harry; Ross, Steven; Amendt, Peter; Girard, Frederic; Villette, Bruno; Reverdin, Charles; Loiseau, Pascal; Caillaud, Tony; Landoas, Olivier; Li, Chi Kang; Petrasso, Richard; Seguin, Fredrick; Rosenberg, Markus

2011-10-01

The rugby hohlraum concept is predicted to enable better coupling and higher gains in the indirect drive approach to ignition. A collaborative experimental program is currently pursued on OMEGA to test this concept in preparation for future megajoule-scale ignition designs. A direct comparison of gas-filled rugby hohlraums with classical cylinders was recently performed, showing a significant (up to ~40%) observed x-ray drive enhancement and neutron yields that are consistently higher in the rugby case. This work extends and confirms our previous findings in empty rugby hohlraums.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorey, Patrick; Halavanau, Aliaksei; Mercer, James

Here, we study boundary scattering in themore » $$\\phi^4$$ model on a half-line with a one-parameter family of Neumann-type boundary conditions. A rich variety of phenomena is observed, which extends previously-studied behaviour on the full line to include regimes of near-elastic scattering, the restoration of a missing scattering window, and the creation of a kink or oscillon through the collision-induced decay of a metastable boundary state. We also study the decay of the vibrational boundary mode, and explore different scenarios for its relaxation and for the creation of kinks.« less

Time delayed Ensemble Nudging Method

NASA Astrophysics Data System (ADS)

An, Zhe; Abarbanel, Henry

Optimal nudging method based on time delayed embedding theory has shows potentials on analyzing and data assimilation in previous literatures. To extend the application and promote the practical implementation, new nudging assimilation method based on the time delayed embedding space is presented and the connection with other standard assimilation methods are studied. Results shows the incorporating information from the time series of data can reduce the sufficient observation needed to preserve the quality of numerical prediction, making it a potential alternative in the field of data assimilation of large geophysical models.

Vertical motions in the Uranian atmosphere - An analysis of radio observations

NASA Technical Reports Server (NTRS)

Hofstadter, Mark D.; Berge, Glenn L.; Muhleman, Duane O.

1990-01-01

The present, 6-cm radio map of Uranus indicates latitudinal features which may be due to vertical motions of the atmosphere. It appears in light of Voyager IR measurements as well as previously obtained radio data that these large-scale vertical motions, which have not undergone significant changes over the course of 8 years, extend from the 0.1- to the 45-bar levels; this span corresponds to a height of the order of 250 km. The latitudinal structures are believed to be primarily caused by horizontal variations of absorber abundances.

High Statistics Measurement of the Positron Fraction in Primary Cosmic Rays of 0.5-500 GeV with the Alpha Magnetic Spectrometer on the International Space Station

NASA Astrophysics Data System (ADS)

Accardo, L.; Aguilar, M.; Aisa, D.; Alvino, A.; Ambrosi, G.; Andeen, K.; Arruda, L.; Attig, N.; Azzarello, P.; Bachlechner, A.; Barao, F.; Barrau, A.; Barrin, L.; Bartoloni, A.; Basara, L.; Battarbee, M.; Battiston, R.; Bazo, J.; Becker, U.; Behlmann, M.; Beischer, B.; Berdugo, J.; Bertucci, B.; Bigongiari, G.; Bindi, V.; Bizzaglia, S.; Bizzarri, M.; Boella, G.; de Boer, W.; Bollweg, K.; Bonnivard, V.; Borgia, B.; Borsini, S.; Boschini, M. J.; Bourquin, M.; Burger, J.; Cadoux, F.; Cai, X. D.; Capell, M.; Caroff, S.; Casaus, J.; Cascioli, V.; Castellini, G.; Cernuda, I.; Cervelli, F.; Chae, M. J.; Chang, Y. H.; Chen, A. I.; Chen, H.; Cheng, G. M.; Chen, H. S.; Cheng, L.; Chikanian, A.; Chou, H. Y.; Choumilov, E.; Choutko, V.; Chung, C. H.; Clark, C.; Clavero, R.; Coignet, G.; Consolandi, C.; Contin, A.; Corti, C.; Coste, B.; Cui, Z.; Dai, M.; Delgado, C.; Della Torre, S.; Demirköz, M. B.; Derome, L.; Di Falco, S.; Di Masso, L.; Dimiccoli, F.; Díaz, C.; von Doetinchem, P.; Du, W. J.; Duranti, M.; D'Urso, D.; Eline, A.; Eppling, F. J.; Eronen, T.; Fan, Y. Y.; Farnesini, L.; Feng, J.; Fiandrini, E.; Fiasson, A.; Finch, E.; Fisher, P.; Galaktionov, Y.; Gallucci, G.; García, B.; García-López, R.; Gast, H.; Gebauer, I.; Gervasi, M.; Ghelfi, A.; Gillard, W.; Giovacchini, F.; Goglov, P.; Gong, J.; Goy, C.; Grabski, V.; Grandi, D.; Graziani, M.; Guandalini, C.; Guerri, I.; Guo, K. H.; Habiby, M.; Haino, S.; Han, K. C.; He, Z. H.; Heil, M.; Hoffman, J.; Hsieh, T. H.; Huang, Z. C.; Huh, C.; Incagli, M.; Ionica, M.; Jang, W. Y.; Jinchi, H.; Kanishev, K.; Kim, G. N.; Kim, K. S.; Kirn, Th.; Kossakowski, R.; Kounina, O.; Kounine, A.; Koutsenko, V.; Krafczyk, M. S.; Kunz, S.; La Vacca, G.; Laudi, E.; Laurenti, G.; Lazzizzera, I.; Lebedev, A.; Lee, H. T.; Lee, S. C.; Leluc, C.; Li, H. L.; Li, J. Q.; Li, Q.; Li, Q.; Li, T. X.; Li, W.; Li, Y.; Li, Z. H.; Li, Z. Y.; Lim, S.; Lin, C. H.; Lipari, P.; Lippert, T.; Liu, D.; Liu, H.; Lomtadze, T.; Lu, M. J.; Lu, Y. S.; Luebelsmeyer, K.; Luo, F.; Luo, J. Z.; Lv, S. S.; Majka, R.; Malinin, A.; Mañá, C.; Marín, J.; Martin, T.; Martínez, G.; Masi, N.; Maurin, D.; Menchaca-Rocha, A.; Meng, Q.; Mo, D. C.; Morescalchi, L.; Mott, P.; Müller, M.; Ni, J. Q.; Nikonov, N.; Nozzoli, F.; Nunes, P.; Obermeier, A.; Oliva, A.; Orcinha, M.; Palmonari, F.; Palomares, C.; Paniccia, M.; Papi, A.; Pedreschi, E.; Pensotti, S.; Pereira, R.; Pilo, F.; Piluso, A.; Pizzolotto, C.; Plyaskin, V.; Pohl, M.; Poireau, V.; Postaci, E.; Putze, A.; Quadrani, L.; Qi, X. M.; Rancoita, P. G.; Rapin, D.; Ricol, J. S.; Rodríguez, I.; Rosier-Lees, S.; Rozhkov, A.; Rozza, D.; Sagdeev, R.; Sandweiss, J.; Saouter, P.; Sbarra, C.; Schael, S.; Schmidt, S. M.; Schuckardt, D.; von Dratzig, A. Schulz; Schwering, G.; Scolieri, G.; Seo, E. S.; Shan, B. S.; Shan, Y. H.; Shi, J. Y.; Shi, X. Y.; Shi, Y. M.; Siedenburg, T.; Son, D.; Spada, F.; Spinella, F.; Sun, W.; Sun, W. H.; Tacconi, M.; Tang, C. P.; Tang, X. W.; Tang, Z. C.; Tao, L.; Tescaro, D.; Ting, Samuel C. C.; Ting, S. M.; Tomassetti, N.; Torsti, J.; Türkoǧlu, C.; Urban, T.; Vagelli, V.; Valente, E.; Vannini, C.; Valtonen, E.; Vaurynovich, S.; Vecchi, M.; Velasco, M.; Vialle, J. P.; Wang, L. Q.; Wang, Q. L.; Wang, R. S.; Wang, X.; Wang, Z. X.; Weng, Z. L.; Whitman, K.; Wienkenhöver, J.; Wu, H.; Xia, X.; Xie, M.; Xie, S.; Xiong, R. Q.; Xin, G. M.; Xu, N. S.; Xu, W.; Yan, Q.; Yang, J.; Yang, M.; Ye, Q. H.; Yi, H.; Yu, Y. J.; Yu, Z. Q.; Zeissler, S.; Zhang, J. H.; Zhang, M. T.; Zhang, X. B.; Zhang, Z.; Zheng, Z. M.; Zhuang, H. L.; Zhukov, V.; Zichichi, A.; Zimmermann, N.; Zuccon, P.; Zurbach, C.; AMS Collaboration

2014-09-01

A precision measurement by AMS of the positron fraction in primary cosmic rays in the energy range from 0.5 to 500 GeV based on 10.9 million positron and electron events is presented. This measurement extends the energy range of our previous observation and increases its precision. The new results show, for the first time, that above ∼200 GeV the positron fraction no longer exhibits an increase with energy.

Vertical structure of stratospheric water vapour trends derived from merged satellite data

PubMed Central

Hegglin, M. I.; Plummer, D. A.; Shepherd, T. G.; Scinocca, J. F.; Anderson, J.; Froidevaux, L.; Funke, B.; Hurst, D.; Rozanov, A.; Urban, J.; von Clarmann, T.; Walker, K. A.; Wang, H. J.; Tegtmeier, S.; Weigel, K.

2017-01-01

Stratospheric water vapour is a powerful greenhouse gas. The longest available record from balloon observations over Boulder, Colorado, USA shows increases in stratospheric water vapour concentrations that cannot be fully explained by observed changes in the main drivers, tropical tropopause temperatures and methane. Satellite observations could help resolve the issue, but constructing a reliable long-term data record from individual short satellite records is challenging. Here we present an approach to merge satellite data sets with the help of a chemistry-climate model nudged to observed meteorology. We use the models' water vapour as a transfer function between data sets that overcomes issues arising from instrument drift and short overlap periods. In the lower stratosphere, our water vapour record extends back to 1988 and water vapour concentrations largely follow tropical tropopause temperatures. Lower and mid-stratospheric long-term trends are negative, and the trends from Boulder are shown not to be globally representative. In the upper stratosphere, our record extends back to 1986 and shows positive long-term trends. The altitudinal differences in the trends are explained by methane oxidation together with a strengthened lower-stratospheric and a weakened upper-stratospheric circulation inferred by this analysis. Our results call into question previous estimates of surface radiative forcing based on presumed global long-term increases in water vapour concentrations in the lower stratosphere. PMID:29263751

Subaru Imaging of Asymmetric Features in a Transitional Disk in Upper Scorpius

NASA Technical Reports Server (NTRS)

Mayama, S.; Hashimoto, J.; Muto, T.; Tsukagoshi, T.; Kusakabe, N.; Kuzuhara, M.; Takahashi, Y.; Kudo, T.; Dong, R.; Fukagawa, M.;

Subaru Imaging of Asymmetric Features in a Transitional Disk in a Transitional Disk in Upper Scorpius

NASA Technical Reports Server (NTRS)

Mayama, S.; Hashimoto, J.; Muto, T.; Tsukagoshi, T.; Kusakabe, N.; Kuzuhara, M.; Takahashi, Y.; Kudo, T.; Dong, R.; Fukagawa, M.;

Vertical structure of stratospheric water vapour trends derived from merged satellite data.

PubMed

Hegglin, M I; Plummer, D A; Shepherd, T G; Scinocca, J F; Anderson, J; Froidevaux, L; Funke, B; Hurst, D; Rozanov, A; Urban, J; von Clarmann, T; Walker, K A; Wang, H J; Tegtmeier, S; Weigel, K

2014-01-01

Stratospheric water vapour is a powerful greenhouse gas. The longest available record from balloon observations over Boulder, Colorado, USA shows increases in stratospheric water vapour concentrations that cannot be fully explained by observed changes in the main drivers, tropical tropopause temperatures and methane. Satellite observations could help resolve the issue, but constructing a reliable long-term data record from individual short satellite records is challenging. Here we present an approach to merge satellite data sets with the help of a chemistry-climate model nudged to observed meteorology. We use the models' water vapour as a transfer function between data sets that overcomes issues arising from instrument drift and short overlap periods. In the lower stratosphere, our water vapour record extends back to 1988 and water vapour concentrations largely follow tropical tropopause temperatures. Lower and mid-stratospheric long-term trends are negative, and the trends from Boulder are shown not to be globally representative. In the upper stratosphere, our record extends back to 1986 and shows positive long-term trends. The altitudinal differences in the trends are explained by methane oxidation together with a strengthened lower-stratospheric and a weakened upper-stratospheric circulation inferred by this analysis. Our results call into question previous estimates of surface radiative forcing based on presumed global long-term increases in water vapour concentrations in the lower stratosphere.

New Measurements of the Cosmic Infrared Background Fluctuations in Deep SpitzerllRAC Survey Data and their Cosmological Implications

NASA Technical Reports Server (NTRS)

Kashlinsky, A.; Arendt, R. G.; Ashby, M. L. N.; Fazio, G. G.; Mather, J.; Moseley, S. H.

2012-01-01

We extend the previous measurements of CIB fluctuations to angular scales of less than or equal to 1 degree new data obtained in the course of the 2,000+ hour Spitzer Extended Deep Survey. Two fields with completed observations of approximately equal to 12 hr/pixel are analyzed for source-subtracted CIB fluctuations at 3.6 and 4.5 micrometers. The fields, EGS and UDS, cover a total area of approximately 0.25 deg and lie at high Galactic and Ecliptic latitudes, thus minimizing cirrus and zodiacal light contributions to the fluctuations. The observations have been conducted at 3 distinct epochs separated by about 6 months. As in our previous studies, the fields were assembled using the self-calibration method which is uniquely suitable for probing faint diffuse backgrounds. The assembled fields were cleaned off the bright sources down to the low shot noise levels corresponding to AB mag approximately equal to 25, Fourier-transformed and their power spectra evaluated. The noise was estimated from the time-differenced data and subtracted from the signal isolating the fluctuations remaining above the noise levels. The power spectra of the source-subtracted fields remain identical (within the observational uncertainties) for the three epochs of observations indicating that zodiacal light contributes negligibly to the fluctuations. By comparing to the measurements for the same regions at 8 micrometers we demonstrate that Galactic cirrus cannot account for the levels of the fluctuations either. The signal appears isotropically distributed on the sky as required by its origin in the CIB fluctuations. This measurement thus extends our earlier results to the important range of sub-degree scales. We find that the CIB fluctuations continue to diverge to more than 10 times those of known galaxy populations on angular scales out to less than or equal to 1 degree. The low shot noise levels remaining in the diffuse maps indicate that the large scale fluctuations arise from spatial clustering of faint sources well within the confusion noise. The spatial spectrum of these fluctuations is in reasonable agreement with simple fitting assuming that they originate in early populations spatially distributed according to the standard cosmological model (ACDM) at epochs coinciding with the first stars era. The alternative to this identification would require a new population never observed before, nor expected on theoretical grounds, but if true this would represent an important discovery in its own right.

Associations between Soluble Receptor for Advanced Glycation End Products (sRAGE) and S100A12 (EN-RAGE) with Mortality in Long-term Hemodialysis Patients.

PubMed

Jung, Eul Sik; Chung, Wookyung; Kim, Ae Jin; Ro, Han; Chang, Jae Hyun; Lee, Hyun Hee; Jung, Ji Yong

2017-01-01

Hemodialysis (HD) patients experience vascular calcification, ultimately leading to high mortality rates. Previously, we reported associations between soluble receptor for advanced glycation end products (sRAGEs) and extracellular newly identified RAGE-binding protein S100A12 (EN-RAGE) and vascular calcification. Here, we extended our observations, investigating whether these biomarkers may be useful for predicting cardiovascular morbidity and mortality in these subjects. Thus, we evaluated the relationship between sRAGE and S100A12 and mortality in long-term HD patients. This was a prospective observational cohort study in 199 HD patients from an extended analysis of our previous study. Plasma sRAGE, S100A12, comorbidities, and other traditional risk factors were investigated. The cumulative incidences for death using Cox proportional hazards regression were evaluated in multivariable analyses. The observation period was 44 months. During the observation period, 27 (13.6%) patients died. Univariate analysis demonstrated that S100A12 was correlated with diabetes (P = 0.040) and high-sensitivity C-reactive protein (hsCRP) (P = 0.006). In multivariable analyses, plasma sRAGE (hazard ratio [HR] = 1.155; 95% confidence interval [CI] = 0.612-2.183; P = 0.656) and S100A12 (HR = 0.960; 95% CI = 0.566-1.630; P = 0.881) were not associated with mortality in HD patients, although traditional predictors of mortality, including age, history of cardiovascular diseases (CVDs), and serum levels of albumin and hsCRP were related to mortality. Powerful predictors of mortality were age, CVD, and albumin levels. Plasma sRAGE and S100A12 may be weak surrogate markers for predicting all-cause mortality in patients undergoing HD, although S100A12 was partly related to diabetes and inflammation.

Applied estimation for hybrid dynamical systems using perceptional information

NASA Astrophysics Data System (ADS)

Plotnik, Aaron M.

This dissertation uses the motivating example of robotic tracking of mobile deep ocean animals to present innovations in robotic perception and estimation for hybrid dynamical systems. An approach to estimation for hybrid systems is presented that utilizes uncertain perceptional information about the system's mode to improve tracking of its mode and continuous states. This results in significant improvements in situations where previously reported methods of estimation for hybrid systems perform poorly due to poor distinguishability of the modes. The specific application that motivates this research is an automatic underwater robotic observation system that follows and films individual deep ocean animals. A first version of such a system has been developed jointly by the Stanford Aerospace Robotics Laboratory and Monterey Bay Aquarium Research Institute (MBARI). This robotic observation system is successfully fielded on MBARI's ROVs, but agile specimens often evade the system. When a human ROV pilot performs this task, one advantage that he has over the robotic observation system in these situations is the ability to use visual perceptional information about the target, immediately recognizing any changes in the specimen's behavior mode. With the approach of the human pilot in mind, a new version of the robotic observation system is proposed which is extended to (a) derive perceptional information (visual cues) about the behavior mode of the tracked specimen, and (b) merge this dissimilar, discrete and uncertain information with more traditional continuous noisy sensor data by extending existing algorithms for hybrid estimation. These performance enhancements are enabled by integrating techniques in hybrid estimation, computer vision and machine learning. First, real-time computer vision and classification algorithms extract a visual observation of the target's behavior mode. Existing hybrid estimation algorithms are extended to admit this uncertain but discrete observation, complementing the information available from more traditional sensors. State tracking is achieved using a new form of Rao-Blackwellized particle filter called the mode-observed Gaussian Particle Filter. Performance is demonstrated using data from simulation and data collected on actual specimens in the ocean. The framework for estimation using both traditional and perceptional information is easily extensible to other stochastic hybrid systems with mode-related perceptional observations available.

Determinants of observed confidant support for divorced mothers.

PubMed

DeGarmo, D S; Forgatch, M S

1997-02-01

Marital separation can be a time of extreme stress and can significantly disrupt support networks and support processes when they are needed most. The purpose of this investigation was to test mechanisms of support erosion in a multimethod study of 138 divorced mothers and their confidants. Previous work was extended by using observational measures of confidant support in a process model including (a) maternal characteristics over time, (b) support person characteristics, and (c) relationship characteristics (intimacy and confidant relationship type). A hypothesized mechanism of erosion was supported in which ongoing maternal distress was positively associated with levels of confidant negativity, which in turn was related to lower levels of observed support. Having a partner was related to more intimacy than was having family and friends. Contrary to expectation, however, having a partner was related to lower levels of support, and intimacy was not related to observed support.

Observation model and parameter partials for the JPL VLBI parameter estimation software MODEST, 19 94

NASA Technical Reports Server (NTRS)

Sovers, O. J.; Jacobs, C. S.

1994-01-01

This report is a revision of the document Observation Model and Parameter Partials for the JPL VLBI Parameter Estimation Software 'MODEST'---1991, dated August 1, 1991. It supersedes that document and its four previous versions (1983, 1985, 1986, and 1987). A number of aspects of the very long baseline interferometry (VLBI) model were improved from 1991 to 1994. Treatment of tidal effects is extended to model the effects of ocean tides on universal time and polar motion (UTPM), including a default model for nearly diurnal and semidiurnal ocean tidal UTPM variations, and partial derivatives for all (solid and ocean) tidal UTPM amplitudes. The time-honored 'K(sub 1) correction' for solid earth tides has been extended to include analogous frequency-dependent response of five tidal components. Partials of ocean loading amplitudes are now supplied. The Zhu-Mathews-Oceans-Anisotropy (ZMOA) 1990-2 and Kinoshita-Souchay models of nutation are now two of the modeling choices to replace the increasingly inadequate 1980 International Astronomical Union (IAU) nutation series. A rudimentary model of antenna thermal expansion is provided. Two more troposphere mapping functions have been added to the repertoire. Finally, corrections among VLBI observations via the model of Treuhaft and lanyi improve modeling of the dynamic troposphere. A number of minor misprints in Rev. 4 have been corrected.

Afferent Connectivity of the Zebrafish Habenulae

PubMed Central

Turner, Katherine J.; Hawkins, Thomas A.; Yáñez, Julián; Anadón, Ramón; Wilson, Stephen W.; Folgueira, Mónica

2016-01-01

The habenulae are bilateral nuclei located in the dorsal diencephalon that are conserved across vertebrates. Here we describe the main afferents to the habenulae in larval and adult zebrafish. We observe afferents from the subpallium, nucleus rostrolateralis, posterior tuberculum, posterior hypothalamic lobe, median raphe; we also see asymmetric afferents from olfactory bulb to the right habenula, and from the parapineal to the left habenula. In addition, we find afferents from a ventrolateral telencephalic nucleus that neurochemical and hodological data identify as the ventral entopeduncular nucleus (vENT), confirming and extending observations of Amo et al. (2014). Fate map and marker studies suggest that vENT originates from the diencephalic prethalamic eminence and extends into the lateral telencephalon from 48 to 120 hour post-fertilization (hpf). No afferents to the habenula were observed from the dorsal entopeduncular nucleus (dENT). Consequently, we confirm that the vENT (and not the dENT) should be considered as the entopeduncular nucleus “proper” in zebrafish. Furthermore, comparison with data in other vertebrates suggests that the vENT is a conserved basal ganglia nucleus, being homologous to the entopeduncular nucleus of mammals (internal segment of the globus pallidus of primates) by both embryonic origin and projections, as previously suggested by Amo et al. (2014). PMID:27199671

Removal of methadone by extended dialysis using a high cut-off dialyzer: implications for the treatment of overdose and for pain management in patients undergoing light chain removal.

PubMed

Arelin, Viktor; Schmidt, Julius J; Kayser, Nathalie; Kühn-Velten, W Nikolaus; Suhling, Hendrik; Eden, Gabriele; Kielstein, Jan T

2016-06-01

The synthetic opioid methadone hydrochloride has a low molecular weight of 346 D, a high volume of distribution (4 - 7 L/kg), and is lipophilic. It is used as an analgesic and for the maintenance treatment of opiate dependence. In drug addicts, methadone is frequently involved in mixed intoxications that can lead to death. Here we present the case of a drug addict in whom a high cut-off dialysis membrane together with extended dialysis was used in the setting of suspected overdose and acute kidney injury. Although the observed dialyzer plasma clearance (31.5 mL/min) and reduction ratio (38%) were higher than previously reported for standard hemodialysis, the total amount of methadone in the spent dialysate after 1 extended dialysis session was quite low. Hence, even extended dialysis with a high cut-off membrane does not seem to offer a clinically relevant benefit in the setting of overdose for enhanced methadone removal. On the other hand, in patients undergoing high cut-off dialysis for the removal of light chains, methadone could still be used as an analgesic without an additional dose after high cut-off hemodialysis.

Long-term preservation of chilled canine semen: effect of commercial and laboratory prepared extenders.

PubMed

Iguer-ouada, M; Verstegen, J P

2001-01-15

The present study was conducted to evaluate chilled semen conservation over time in 3 commercial and 4 laboratory prepared extenders, including a new Tris-glucose extender. The beneficial effect of adding egg yolk to these media was also analyzed. The effects of these extenders on motility and acrosome reaction were characterized objectively using a computer-aided semen analyzer and the chlortetracycline staining, respectively. No significant differences were observed when comparing the different commercial extenders without egg yolk, but addition of egg yolk improved all motility parameters significantly (preservation of 50% of motility was observed at 3.2+/-1, 2.9+/-0.5, 2.3+/-0.5, 8.5+/-0.2, 5.4+/-1.1, 5.2+/-0.4 d, for Biladyl, green extender and fresh-phos extenders without and with egg yolk, respectively). Motility parameters were best preserved in egg yolk supplemented Biladyl extender with a mean percentage of 86.3+/-10.5 motile spermatozoa after 7 d at 4 degrees C. Efficacy of egg yolk-supplemented commercial extenders on sperm motility at 4 degrees C was (in decreasing order) as follows: Biladyl > green extender > fresh-phos. However, high quality motility and the percentage of motile spermatozoa were highest with some of the laboratory prepared extenders: a 50% conservation rate of motile spermatozoa was observed following the use of supplemented egg yolk extenders. These are classified in decreasing order as follows: Tris-glucose (13+/-1 d) > Tris-fructose (9.7+/-0.6) > EDTA (4.+/-0.6 d) > Tris-bes (3.6+/-1.1 d). A low concentration of motile spermatozoa was still observed in the Tris-glucose egg yolk extender 16 d after collection, clearly demonstrating the importance of the medium and the beneficial effect of egg yolk on sperm motility of 4 degrees C chilled semen. Similar effects of extender were observed for acrosome reactions. Egg yolk clearly had a protective effect reducing acrosome reactions significantly in all media tested as follows: the highest acrosome losses were observed in the fresh-phos and EDTA extenders without egg yolk; the lowest rate was observed with Tris-glucose supplemented egg yolk extender. In conclusion, at 4 degrees C, egg yolk extender best-protected sperm motility parameters. Differences in osmolarity between the extenders in terms of substrate related to sperm metabolic activity may explain the optimal results obtained using egg yolk-supplemented Tris-glucose extender, which preserved motility and acrosome integrity in chilled dog semen. These results indicated that good quality dog spermatozoa could be preserved for up to 10 d.

Ongoing Mars Missions: Extended Mission Plans

NASA Astrophysics Data System (ADS)

Zurek, Richard; Diniega, Serina; Crisp, Joy; Fraeman, Abigail; Golombek, Matt; Jakosky, Bruce; Plaut, Jeff; Senske, David A.; Tamppari, Leslie; Thompson, Thomas W.; Vasavada, Ashwin R.

2016-10-01

Many key scientific discoveries in planetary science have been made during extended missions. This is certainly true for the Mars missions both in orbit and on the planet's surface. Every two years, ongoing NASA planetary missions propose investigations for the next two years. This year, as part of the 2016 Planetary Sciences Division (PSD) Mission Senior Review, the Mars Odyssey (ODY) orbiter project submitted a proposal for its 7th extended mission, the Mars Exploration Rover (MER-B) Opportunity submitted for its 10th, the Mars Reconnaissance Orbiter (MRO) for its 4th, and the Mars Science Laboratory (MSL) Curiosity rover and the Mars Atmosphere and Volatile Evolution (MVN) orbiter for their 2nd extended missions, respectively. Continued US participation in the ongoing Mars Express Mission (MEX) was also proposed. These missions arrived at Mars in 2001, 2004, 2006, 2012, 2014, and 2003, respectively. Highlights of proposed activities include systematic observations of the surface and atmosphere in twilight (early morning and late evening), building on a 13-year record of global mapping (ODY); exploration of a crater rim gully and interior of Endeavour Crater, while continuing to test what can and cannot be seen from orbit (MER-B); refocused observations of ancient aqueous deposits and polar cap interiors, while adding a 6th Mars year of change detection in the atmosphere and the surface (MRO); exploration and sampling by a rover of mineralogically diverse strata of Mt. Sharp and of atmospheric methane in Gale Crater (MSL); and further characterization of atmospheric escape under different solar conditions (MVN). As proposed, these activities follow up on previous discoveries (e.g., recurring slope lineae, habitable environments), while expanding spatial and temporal coverage to guide new detailed observations. An independent review panel evaluated these proposals, met with project representatives in May, and made recommendations to NASA in June 2016. In this presentation, we will highlight the planned activities of these NASA Mars missions, as they start new chapters in their historic exploration of the dynamic and complex planet that is Mars.

Long-term evolution of Oort Cloud comets: capture of comets

NASA Astrophysics Data System (ADS)

Nurmi, P.; Valtonen, M. J.; Zheng, J. Q.; Rickman, H.

2002-07-01

We test different possibilities for the origin of short-period comets captured from the Oort Cloud. We use an efficient Monte Carlo simulation method that takes into account non-gravitational forces, Galactic perturbations, observational selection effects, physical evolution and tidal splittings of comets. We confirm previous results and conclude that the Jupiter family comets cannot originate in the spherically distributed Oort Cloud, since there is no physically possible model of how these comets can be captured from the Oort Cloud flux and produce the observed inclination and Tisserand constant distributions. The extended model of the Oort Cloud predicted by the planetesimal theory consisting of a non-randomly distributed inner core and a classical Oort Cloud also cannot explain the observed distributions of Jupiter family comets. The number of comets captured from the outer region of the Solar system are too high compared with the observations if the inclination distribution of Jupiter family comets is matched with the observed distribution. It is very likely that the Halley-type comets are captured mainly from the classical Oort Cloud, since the distributions in inclination and Tisserand value can be fitted to the observed distributions with very high confidence. Also the expected number of comets is in agreement with the observations when physical evolution of the comets is included. However, the solution is not unique, and other more complicated models can also explain the observed properties of Halley-type comets. The existence of Jupiter family comets can be explained only if they are captured from the extended disc of comets with semimajor axes of the comets a<5000au. The original flattened distribution of comets is conserved as the cometary orbits evolve from the outer Solar system era to the observed region.

Gamma ray sources observation with the ARGO-YBJ detector

NASA Astrophysics Data System (ADS)

Vernetto, S.; ARGO-YBJ Collaboration

2011-02-01

In this paper we report on the observations of TeV gamma ray sources performed by the air shower detector ARGO-YBJ. The objects studied in this work are the blazar Markarian 421 and the extended galactic source MGROJ1908+06, monitored during ~2 years of operation. Mrk421 has been detected by ARGO-YBJ with a statistical significance of ~11 standard deviations. The observed TeV emission was highly variable, showing large enhancements of the flux during active periods. The study of the spectral behaviour during flares revealed a positive correlation of the hardness with the flux, as already reported in the past by the Whipple telescope, suggesting that this is a long term property of the source. ARGO-YBJ observed a strong correlation between TeV gamma rays and the X-ray flux measured by RXTM/ASM and SWIFT/BAT during the whole period, with a time lag compatible with zero, supporting the one-zone SSC model to describe the emission mechanism. MGROJ1908+06 has been detected by ARGO-YBJ with ~5 standard deviation of significance. From our data the source appears extended and the measured extension is σext = 0.48° --> σext = 0.48° -0.28+0.26 --> -0.28+0.26, in agreement with a previous HESS observation. The average flux is in marginal agreement with that reported by MILAGRO, but significantly higher than that obtained by HESS, suggesting a possible flux variability.

Generation of VLF saucer emissions observed by the Viking satellite

NASA Astrophysics Data System (ADS)

Lonnqvist, H.; Andre, M.; Matson, L.; Bahnsen, A.; Blomberg, L. G.; Erlandson, R. E.

1993-08-01

Simultaneous observations by the Viking satellite of electric and magnetic fields as well as charged particles have been used to investigate V-shaped wave phenomena. The intensity of these VLF and ELF emissions is V-shaped when shown in a frequency versus time plot. Simultaneous observations of V-shaped so-called VLF saucer emissions, particles and field-aligned currents strongly suggest, for the first time, that upgoing electrons with energies less than a few hundred electron volts can generate these waves. Broadband waves observed inside the saucer generation region, from frequencies much less than the ion cyclotron frequency up to the plasma frequency, may also be generated by these electrons. Viking observations of VLF saucers at altitudes between 4000 km and 13,500 km show that these emissions occur at higher altitudes than discussed in previous reports. The generation regions seem to be more extended at these higher altitudes than what has been reported at lower altitudes by other observers.

Dibaryons with Strangeness in Quark Models

NASA Astrophysics Data System (ADS)

Chen, Mei; Gong, Fang; Huang, Hongxia; Ping, Jialun

The extended quark delocalization color screening model, which incorporates Goldstone-boson-exchange with soft cutoff, and chiral quark model are employed to do a systematic dynamical calculation of six-quark systems with strangeness. The two models give similar results, although they have different attraction mechanisms. Comparing with the previous calculation of the extended quark delocalization color screening model, in which the Goldstone-bosons are introduced with hard cutoff, the present calculation obtains a little large binding energies for most of the states. However, the conclusions are the same. The calculations show that NΩ state with IJ = 1/2, 2 is a good dibaryon candidate with narrow width, and ΩΩ state with IJ = 00 is a stable dibaryon against the strong interaction. The calculations also reveal several other possible dibaryon candidates with high angular momentum, ΔΣ*(1/2, 3), ΔΞ*(1, 3), etc. These states may have too wide width to be observed experimentally.

ENSO-based probabilistic forecasts of March-May U.S. tornado and hail activity

NASA Astrophysics Data System (ADS)

Lepore, Chiara; Tippett, Michael K.; Allen, John T.

2017-09-01

Extended logistic regression is used to predict March-May severe convective storm (SCS) activity based on the preceding December-February (DJF) El Niño-Southern Oscillation (ENSO) state. The spatially resolved probabilistic forecasts are verified against U.S. tornado counts, hail events, and two environmental indices for severe convection. The cross-validated skill is positive for roughly a quarter of the U.S. Overall, indices are predicted with more skill than are storm reports, and hail events are predicted with more skill than tornado counts. Skill is higher in the cool phase of ENSO (La Niña like) when overall SCS activity is higher. SCS forecasts based on the predicted DJF ENSO state from coupled dynamical models initialized in October of the previous year extend the lead time with only a modest reduction in skill compared to forecasts based on the observed DJF ENSO state.

Self-Assembly of Trimer Colloids: Effect of Shape and Interaction Range†

PubMed Central

Hatch, Harold W.; Yang, Seung-Yeob; Mittal, Jeetain; Shen, Vincent K.

2016-01-01

Trimers with one attractive bead and two repulsive beads, similar to recently synthesized trimer patchy colloids, were simulated with flat-histogram Monte Carlo methods to obtain the stable self-assembled structures for different shapes and interaction potentials. Extended corresponding states principle was successfully applied to self-assembling systems in order to approximately collapse the results for models with the same shape, but different interaction range. This helps us directly compare simulation results with previous experiment, and good agreement was found between the two. In addition, a variety of self-assembled structures were observed by varying the trimer geometry, including spherical clusters, elongated clusters, monolayers, and spherical shells. In conclusion, our results help to compare simulations and experiments, via extended corresponding states, and we predict the formation of self-assembled structures for trimer shapes that have not been experimentally synthesized. PMID:27087490

Extending the Search for Neutrino Point Sources with IceCube above the Horizon

NASA Astrophysics Data System (ADS)

Abbasi, R.; Abdou, Y.; Abu-Zayyad, T.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Andeen, K.; Auffenberg, J.; Bai, X.; Baker, M.; Barwick, S. W.; Bay, R.; Alba, J. L. Bazo; Beattie, K.; Beatty, J. J.; Bechet, S.; Becker, J. K.; Becker, K.-H.; Benabderrahmane, M. L.; Berdermann, J.; Berghaus, P.; Berley, D.; Bernardini, E.; Bertrand, D.; Besson, D. Z.; Bissok, M.; Blaufuss, E.; Boersma, D. J.; Bohm, C.; Botner, O.; Bradley, L.; Braun, J.; Breder, D.; Carson, M.; Castermans, T.; Chirkin, D.; Christy, B.; Clem, J.; Cohen, S.; Cowen, D. F.; D'Agostino, M. V.; Danninger, M.; Day, C. T.; de Clercq, C.; Demirörs, L.; Depaepe, O.; Descamps, F.; Desiati, P.; de Vries-Uiterweerd, G.; Deyoung, T.; Díaz-Vélez, J. C.; Dreyer, J.; Dumm, J. P.; Duvoort, M. R.; Edwards, W. R.; Ehrlich, R.; Eisch, J.; Ellsworth, R. W.; Engdegård, O.; Euler, S.; Evenson, P. A.; Fadiran, O.; Fazely, A. R.; Feusels, T.; Filimonov, K.; Finley, C.; Foerster, M. M.; Fox, B. D.; Franckowiak, A.; Franke, R.; Gaisser, T. K.; Gallagher, J.; Ganugapati, R.; Gerhardt, L.; Gladstone, L.; Goldschmidt, A.; Goodman, J. A.; Gozzini, R.; Grant, D.; Griesel, T.; Groß, A.; Grullon, S.; Gunasingha, R. M.; Gurtner, M.; Ha, C.; Hallgren, A.; Halzen, F.; Han, K.; Hanson, K.; Hasegawa, Y.; Helbing, K.; Herquet, P.; Hickford, S.; Hill, G. C.; Hoffman, K. D.; Homeier, A.; Hoshina, K.; Hubert, D.; Huelsnitz, W.; Hülß, J.-P.; Hulth, P. O.; Hultqvist, K.; Hussain, S.; Imlay, R. L.; Inaba, M.; Ishihara, A.; Jacobsen, J.; Japaridze, G. S.; Johansson, H.; Joseph, J. M.; Kampert, K.-H.; Kappes, A.; Karg, T.; Karle, A.; Kelley, J. L.; Kemming, N.; Kenny, P.; Kiryluk, J.; Kislat, F.; Klein, S. R.; Knops, S.; Kohnen, G.; Kolanoski, H.; Köpke, L.; Koskinen, D. J.; Kowalski, M.; Kowarik, T.; Krasberg, M.; Krings, T.; Kroll, G.; Kuehn, K.; Kuwabara, T.; Labare, M.; Lafebre, S.; Laihem, K.; Landsman, H.; Lauer, R.; Lehmann, R.; Lennarz, D.; Lundberg, J.; Lünemann, J.; Madsen, J.; Majumdar, P.; Maruyama, R.; Mase, K.; Matis, H. S.; McParland, C. P.; Meagher, K.; Merck, M.; Mészáros, P.; Meures, T.; Middell, E.; Milke, N.; Miyamoto, H.; Montaruli, T.; Morse, R.; Movit, S. M.; Nahnhauer, R.; Nam, J. W.; Nießen, P.; Nygren, D. R.; Odrowski, S.; Olivas, A.; Olivo, M.; Ono, M.; Panknin, S.; Patton, S.; Paul, L.; de Los Heros, C. Pérez; Petrovic, J.; Piegsa, A.; Pieloth, D.; Pohl, A. C.; Porrata, R.; Potthoff, N.; Price, P. B.; Prikockis, M.; Przybylski, G. T.; Rawlins, K.; Redl, P.; Resconi, E.; Rhode, W.; Ribordy, M.; Rizzo, A.; Rodrigues, J. P.; Roth, P.; Rothmaier, F.; Rott, C.; Roucelle, C.; Rutledge, D.; Ruzybayev, B.; Ryckbosch, D.; Sander, H.-G.; Sarkar, S.; Schatto, K.; Schlenstedt, S.; Schmidt, T.; Schneider, D.; Schukraft, A.; Schulz, O.; Schunck, M.; Seckel, D.; Semburg, B.; Seo, S. H.; Sestayo, Y.; Seunarine, S.; Silvestri, A.; Slipak, A.; Spiczak, G. M.; Spiering, C.; Stamatikos, M.; Stanev, T.; Stephens, G.; Stezelberger, T.; Stokstad, R. G.; Stoufer, M. C.; Stoyanov, S.; Strahler, E. A.; Straszheim, T.; Sullivan, G. W.; Swillens, Q.; Taboada, I.; Tamburro, A.; Tarasova, O.; Tepe, A.; Ter-Antonyan, S.; Terranova, C.; Tilav, S.; Toale, P. A.; Tooker, J.; Tosi, D.; Turčan, D.; van Eijndhoven, N.; Vandenbroucke, J.; van Overloop, A.; van Santen, J.; Voigt, B.; Walck, C.; Waldenmaier, T.; Wallraff, M.; Walter, M.; Wendt, C.; Westerhoff, S.; Whitehorn, N.; Wiebe, K.; Wiebusch, C. H.; Wiedemann, A.; Wikström, G.; Williams, D. R.; Wischnewski, R.; Wissing, H.; Woschnagg, K.; Xu, C.; Xu, X. W.; Yodh, G.; Yoshida, S.

2009-11-01

Point source searches with the IceCube neutrino telescope have been restricted to one hemisphere, due to the exclusive selection of upward going events as a way of rejecting the atmospheric muon background. We show that the region above the horizon can be included by suppressing the background through energy-sensitive cuts. This improves the sensitivity above PeV energies, previously not accessible for declinations of more than a few degrees below the horizon due to the absorption of neutrinos in Earth. We present results based on data collected with 22 strings of IceCube, extending its field of view and energy reach for point source searches. No significant excess above the atmospheric background is observed in a sky scan and in tests of source candidates. Upper limits are reported, which for the first time cover point sources in the southern sky up to EeV energies.

Surface mass diffusion over an extended temperature range on Pt(111)

NASA Astrophysics Data System (ADS)

Rajappan, M.; Swiech, W.; Ondrejcek, M.; Flynn, C. P.

2007-06-01

Surface mass diffusion is investigated on Pt(111) at temperatures in the range 710-1220 K. This greatly extends the range over which diffusion is known from step fluctuation spectroscopy (SFS). In the present research, a beam of Pt- self-ions is employed to create a suitable structure on step edges. The surface mass diffusion coefficients then follow from the decay of Fourier components observed by low-energy electron microscopy (LEEM) at selected annealing temperatures. The results agree with SFS values where they overlap, and continue smoothly to low temperature. This makes it unlikely that diffusion along step edges plays a major role in step edge relaxation through the temperature range studied. The surface mass diffusion coefficient for the range 710-1520 K deduced from the present work, together with previous SFS data, is Ds = 4 × 10-3 exp(-1.47 eV/kBT) cm2 s-1.

Extended gamma-ray sources around pulsars constrain the origin of the positron flux at Earth.

PubMed

Abeysekara, A U; Albert, A; Alfaro, R; Alvarez, C; Álvarez, J D; Arceo, R; Arteaga-Velázquez, J C; Avila Rojas, D; Ayala Solares, H A; Barber, A S; Bautista-Elivar, N; Becerril, A; Belmont-Moreno, E; BenZvi, S Y; Berley, D; Bernal, A; Braun, J; Brisbois, C; Caballero-Mora, K S; Capistrán, T; Carramiñana, A; Casanova, S; Castillo, M; Cotti, U; Cotzomi, J; Coutiño de León, S; De León, C; De la Fuente, E; Dingus, B L; DuVernois, M A; Díaz-Vélez, J C; Ellsworth, R W; Engel, K; Enríquez-Rivera, O; Fiorino, D W; Fraija, N; García-González, J A; Garfias, F; Gerhardt, M; González Muñoz, A; González, M M; Goodman, J A; Hampel-Arias, Z; Harding, J P; Hernández, S; Hernández-Almada, A; Hinton, J; Hona, B; Hui, C M; Hüntemeyer, P; Iriarte, A; Jardin-Blicq, A; Joshi, V; Kaufmann, S; Kieda, D; Lara, A; Lauer, R J; Lee, W H; Lennarz, D; Vargas, H León; Linnemann, J T; Longinotti, A L; Luis Raya, G; Luna-García, R; López-Coto, R; Malone, K; Marinelli, S S; Martinez, O; Martinez-Castellanos, I; Martínez-Castro, J; Martínez-Huerta, H; Matthews, J A; Miranda-Romagnoli, P; Moreno, E; Mostafá, M; Nellen, L; Newbold, M; Nisa, M U; Noriega-Papaqui, R; Pelayo, R; Pretz, J; Pérez-Pérez, E G; Ren, Z; Rho, C D; Rivière, C; Rosa-González, D; Rosenberg, M; Ruiz-Velasco, E; Salazar, H; Salesa Greus, F; Sandoval, A; Schneider, M; Schoorlemmer, H; Sinnis, G; Smith, A J; Springer, R W; Surajbali, P; Taboada, I; Tibolla, O; Tollefson, K; Torres, I; Ukwatta, T N; Vianello, G; Weisgarber, T; Westerhoff, S; Wisher, I G; Wood, J; Yapici, T; Yodh, G; Younk, P W; Zepeda, A; Zhou, H; Guo, F; Hahn, J; Li, H; Zhang, H

2017-11-17

The unexpectedly high flux of cosmic-ray positrons detected at Earth may originate from nearby astrophysical sources, dark matter, or unknown processes of cosmic-ray secondary production. We report the detection, using the High-Altitude Water Cherenkov Observatory (HAWC), of extended tera-electron volt gamma-ray emission coincident with the locations of two nearby middle-aged pulsars (Geminga and PSR B0656+14). The HAWC observations demonstrate that these pulsars are indeed local sources of accelerated leptons, but the measured tera-electron volt emission profile constrains the diffusion of particles away from these sources to be much slower than previously assumed. We demonstrate that the leptons emitted by these objects are therefore unlikely to be the origin of the excess positrons, which may have a more exotic origin. Copyright © 2017, American Association for the Advancement of Science.

The Extended Concept Of Symmetropy And Its Application To Earthquakes And Acoustic Emissions

NASA Astrophysics Data System (ADS)

Nanjo, K.; Yodogawa, E.

2003-12-01

There is the notion of symmetropy that can be considered as a powerful tool to measure quantitatively entropic heterogeneity regarding symmetry of a pattern. It can be regarded as a quantitative measure to extract the feature of asymmetry of a pattern (Yodogawa, 1982; Nanjo et al., 2000, 2001, 2002 in press). In previous studies, symmetropy was estimated for the spatial distributions of acoustic emissions generated before the ultimate whole fracture of a rock specimen in the laboratory experiment and for the spatial distributions of earthquakes in the seismic source model with self-organized criticality (SOC). In each of these estimations, the outline of the region in which symmetropy is estimated for a pattern is determined to be equal to that of the rock specimen in which acoustic emissions are generated or that of the SOC seismic source model from which earthquakes emerge. When local seismicities like aftershocks, foreshocks and earthquake swarms in the Earth's crust are considered, it is difficult to determine objectively the outline of the region characterizing these local seismicities without the need of subjectiveness. So, the original concept of symmetropy is not appropriate to be directly applied to such local seismicities and the proper modification of the original one is needed. Here, we introduce the notion of symmetropy for the nonlinear geosciences and extend it for the purpose of the application to local seismicities such as aftershocks, foreshocks and earthquake swarms. We employ the extended concept to the spatial distributions of acoustic emissions generated in a previous laboratory experiment where the failure process in a brittle granite sample can be stabilized by controlling axial stress to maintain a constant rate of acoustic emissions and, as a result, detailed view of fracture nucleation and growth was observed. Moreover, it is applied to the temporal variations of spatial distributions of aftershocks and foreshocks of the main shocks, using natural observable data of earthquakes in and around Japan. Our results show the successful applicability of the extended concept of symmetropy to earthquakes and acoustic emissions. Furthermore, it is pointed out that the concept of symmetropy or the extended one of it might be adapted to any pattern recognition in many fields of science, particularly in the nonlinear geosciences and the sciences of complexity. References: Yodogawa, 1982, Percept. Psychophys., v. 32, p. 230-240; Nanjo et al., 2000, Forma, v. 15, p. 95-101; Nanjo et al., 2001, Forma, v. 16, p. 213-224; Nanjo et al., 2002 in press, Symmetry: Art and Science, v. 2.

Extended access to methamphetamine self-administration up-regulates dopamine transporter levels 72 hours after withdrawal in rats.

PubMed

D'Arcy, Christina; Luevano, Joe E; Miranda-Arango, Manuel; Pipkin, Joseph A; Jackson, Jonathan A; Castañeda, Eddie; Gosselink, Kristin L; O'Dell, Laura E

2016-01-01

Previous studies have demonstrated that there are persistent changes in dopamine systems following withdrawal from methamphetamine (METH). This study examined changes in striatal dopamine transporter (DAT), tyrosine hydroxylase (TH) and dopamine receptor 2 (D2) 72 h after withdrawal from METH intravenous self- administration (IVSA). Rats were given limited (1h) or extended (6h) access to METH IVSA (0.05 mg/kg/0.1 ml infusion) for 22 days. Controls did not receive METH IVSA. The rats given extended access to IVSA displayed higher METH intake during the first hour of drug access compared to rats given limited access. Extended access to METH also produced a concomitant increase in striatal DAT levels relative to drug-naïve controls. There were no changes in TH or D2 levels across groups. Previous studies have reported a decrease in striatal DAT levels during protracted periods (>7 days) of withdrawal from METH IVSA. This study extends previous work by showing an increase in striatal DAT protein expression during an earlier time point of withdrawal from this drug. These results are an important step toward understanding the dynamic changes in dopamine systems that occur during different time points of withdrawal from METH IVSA. Copyright © 2015 Elsevier B.V. All rights reserved.

Persistence of collective behavior at high spin in the N = 88 nucleus Tb 153

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartley, D. J.; Riley, M. A.; Wang, X.

Excited states in the N = 88 nucleus Tb-153 were observed up to spin similar to 40 in an experiment utilizing the Gammasphere array. The Tb-153 states were populated in a weak alpha 4n evaporation channel of the Cl-37 + Sn-124 reaction. Two previously known sequences were extended to higher spins, and a new decoupled structure was identified. The pi h(11/2) band was observed in the spin region where other N = 88 isotopes exhibit effects of prolate to oblate shape changes leading to band termination along the yrast line, whereas Tb-153 displays a persistent collective behavior. However, minor perturbationsmore » of the very highest state in both signatures of this h(11/2) band are observed, which perhaps signal the start of the transition towards band termination.« less

Eukaryotic chaperonin containing T-complex polypeptide 1 interacts with filamentous actin and reduces the initial rate of actin polymerization in vitro

PubMed Central

Grantham, Julie; Ruddock, Lloyd W.; Roobol, Anne; Carden, Martin J.

2002-01-01

We have previously observed that subunits of the chaperonin required for actin production (type-II chaperonin containing T-complex polypeptide 1 [CCT]) localize at sites of microfilament assembly. In this article we extend this observation by showing that substantially substoichiometric CCT reduces the initial rate of pyrene-labeled actin polymerization in vitro where eubacterial chaperonin GroEL had no such effect. CCT subunits bound selectively to F-actin in cosedimentation assays, and CCT reduced elongation rates from both purified actin filament “seeds” and the short and stabilized, minus-end blocked filaments in erythrocyte membrane cytoskeletons. These observations suggest CCT might remain involved in biogenesis of the actin cytoskeleton, by acting at filament (+) ends, beyond its already well-established role in producing new actin monomers. PMID:12482199

Spiral density waves in a young protoplanetary disk.

PubMed

Pérez, Laura M; Carpenter, John M; Andrews, Sean M; Ricci, Luca; Isella, Andrea; Linz, Hendrik; Sargent, Anneila I; Wilner, David J; Henning, Thomas; Deller, Adam T; Chandler, Claire J; Dullemond, Cornelis P; Lazio, Joseph; Menten, Karl M; Corder, Stuartt A; Storm, Shaye; Testi, Leonardo; Tazzari, Marco; Kwon, Woojin; Calvet, Nuria; Greaves, Jane S; Harris, Robert J; Mundy, Lee G

2016-09-30

Gravitational forces are expected to excite spiral density waves in protoplanetary disks, disks of gas and dust orbiting young stars. However, previous observations that showed spiral structure were not able to probe disk midplanes, where most of the mass is concentrated and where planet formation takes place. Using the Atacama Large Millimeter/submillimeter Array, we detected a pair of trailing symmetric spiral arms in the protoplanetary disk surrounding the young star Elias 2-27. The arms extend to the disk outer regions and can be traced down to the midplane. These millimeter-wave observations also reveal an emission gap closer to the star than the spiral arms. We argue that the observed spirals trace shocks of spiral density waves in the midplane of this young disk. Copyright © 2016, American Association for the Advancement of Science.

SMM detection of diffuse Galactic 511 keV annihilation radiation

NASA Technical Reports Server (NTRS)

Share, G. H.; Kinzer, R. L.; Kurfess, J. D.; Messina, D. C.; Purcell, W. R.

1988-01-01

Observations of the 511 keV annihilation line from the vicinity of the Galactic center from October to February for 1980/1981, 1981/1982, 1982/1983, 1984/1985, and 1985/1986 are presented. The measurements were made with the gamma-ray spectrometer on the SMM. The design of the instrument and some of its properties used in the analysis are described, and the methods used for accumulating, fitting, and analyzing the data are outlined. It is shown how the Galactic 511 keV line was separated from the intense and variable background observed in orbit. The SMM observations are compared with previous measurements of annihilation radiation from the Galactic center region, and the astrophysical implications are discussed. It is argued that most of the measurements made to date suggest the presence of an extended Galactic source of annihilation radiation.

Doughnut strikes sandwich: the geometry of hot medium in accreting black hole X-ray binaries

NASA Astrophysics Data System (ADS)

Poutanen, Juri; Veledina, Alexandra; Zdziarski, Andrzej A.

2018-06-01

We study the effects of the mutual interaction of hot plasma and cold medium in black hole binaries in their hard spectral state. We consider a number of different geometries. In contrast to previous theoretical studies, we use a modern energy-conserving code for reflection and reprocessing from cold media. We show that a static corona above an accretion disc extending to the innermost stable circular orbit produces spectra not compatible with those observed. They are either too soft or require a much higher disc ionization than that observed. This conclusion confirms a number of previous findings, but disproves a recent study claiming an agreement of that model with observations. We show that the cold disc has to be truncated in order to agree with the observed spectral hardness. However, a cold disc truncated at a large radius and replaced by a hot flow produces spectra which are too hard if the only source of seed photons for Comptonization is the accretion disc. Our favourable geometry is a truncated disc coexisting with a hot plasma either overlapping with the disc or containing some cold matter within it, also including seed photons arising from cyclo-synchrotron emission of hybrid electrons, i.e. containing both thermal and non-thermal parts.

77 FR 40834 - Proposed Amendment of Class E Airspace; Dillon, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... further expand the previous proposed amendment of Class E airspace extending upward from 700 feet above... an amendment of Class E airspace extending upward from 700 feet above the surface. DATES: Comments... published a NPRM to modify Class E airspace, extending upward from 700 feet or more above the surface, at...

Sensor Webs with a Service-Oriented Architecture for On-demand Science Products

NASA Technical Reports Server (NTRS)

Mandl, Daniel; Ungar, Stephen; Ames, Troy; Justice, Chris; Frye, Stuart; Chien, Steve; Tran, Daniel; Cappelaere, Patrice; Derezinsfi, Linda; Paules, Granville;

Effects of irregularity anisotropy on Faraday polarization fluctuations

NASA Technical Reports Server (NTRS)

Lee, M. C.; Nghiem, S. V.; Yoo, C.

1989-01-01

The previous model (Lee et al., 1982) of the Faraday polarization fluctuations (FPF) is extended after taking into account the anisotropic nature of the commonly observed, rodlike and sheetlike ionospheric irregularities. Striking effects of irregularity anisotropy are found in the longitudinal radio propagation. However, if the wave propagation angle is not small (say, greater than 5 deg), the effects of irregularity anisotropy on FPF introduced by rodlike irregularities weaken significantly, while those caused by sheetlike irregularities remain prominent. Therefore, under the same ionospheric propagation conditions, sheetlike ionospheric irregularities are more effective than rodlike ionospheric irregularities in causing the FPF of radio waves. It is expected that intense FPF of VHF radio signals can be observed not only near the equatorial anomaly but also in the auroral region.

Extending Value of Information Methods to Include the Co-Net Benefits of Earth Observations

NASA Astrophysics Data System (ADS)

Macauley, M.

2015-12-01

The widening relevance of Earth observations information across the spectrum of natural and environmental resources markedly enhances the value of these observations. An example is observations of forest extent, species composition, health, and change; this information can help in assessing carbon sequestration, biodiversity and habitat, watershed management, fuelwood potential, and other ecosystem services as well as inform the opportunity cost of forest removal for alternative land use such as agriculture, pasture, or development. These "stacked" indicators or co- net benefits add significant value to Earth observations. In part because of reliance on case studies, much previous research about the value of information from Earth observations has assessed individual applications rather than aggregate across applications, thus tending to undervalue the observations. Aggregating across applications is difficult, however, because it requires common units of measurement: controlling for spatial, spectral, and temporal attributes of the observations; and consistent application of value of information techniques. This paper will discuss general principles of co-net benefit aggregation and illustrate its application to attributing value to Earth observations.

Production version of the extended NASA-Langley Vortex Lattice FORTRAN computer program. Volume 1: User's guide

NASA Technical Reports Server (NTRS)

Lamar, J. E.; Herbert, H. E.

1982-01-01

The latest production version, MARK IV, of the NASA-Langley vortex lattice computer program is summarized. All viable subcritical aerodynamic features of previous versions were retained. This version extends the previously documented program capabilities to four planforms, 400 panels, and enables the user to obtain vortex-flow aerodynamics on cambered planforms, flowfield properties off the configuration in attached flow, and planform longitudinal load distributions.

The effects of sleep deprivation on emotional empathy.

PubMed

Guadagni, Veronica; Burles, Ford; Ferrara, Michele; Iaria, Giuseppe

2014-12-01

Previous studies have shown that sleep loss has a detrimental effect on the ability of the individuals to process emotional information. In this study, we tested the hypothesis that this negative effect extends to the ability of experiencing emotions while observing other individuals, i.e. emotional empathy. To test this hypothesis, we assessed emotional empathy in 37 healthy volunteers who were assigned randomly to one of three experimental groups: one group was tested before and after a night of total sleep deprivation (sleep deprivation group), a second group was tested before and after a usual night of sleep spent at home (sleep group) and the third group was tested twice during the same day (day group). Emotional empathy was assessed by using two parallel versions of a computerized test measuring direct (i.e. explicit evaluation of empathic concern) and indirect (i.e. the observer's reported physiological arousal) emotional empathy. The results revealed that the post measurements of both direct and indirect emotional empathy of participants in the sleep deprivation group were significantly lower than those of the sleep and day groups; post measurement scores of participants in the day and sleep groups did not differ significantly for either direct or indirect emotional empathy. These data are consistent with previous studies showing the negative effect of sleep deprivation on the processing of emotional information, and extend these effects to emotional empathy. The findings reported in our study are relevant to healthy individuals with poor sleep habits, as well as clinical populations suffering from sleep disturbances. © 2014 European Sleep Research Society.

Neuronal nitric oxide synthase mediates the effect of ethanol on IgA.

PubMed

Budec, Mirela; Markovic, Dragana; Vignjevic, Sanja; Mitrovic, Olivera; Dikic, Dragoslava; Koko, Vesna; Cokic, Vladan P

2013-01-01

We showed previously that the acute effect of ethanol on intestinal immunoglobulin A (IgA) expression might be mediated by endogenous nitric oxide (NO). To extend these findings, this study was designed to investigate a possible role of neuronal NO synthase (nNOS) in the observed phenomenon, using 7-nitroindazole (7-NI), a selective inhibitor of its activity. Adult male Wistar rats were treated with: (a) ethanol (4 g/kg, intraperitoneally, i.p.), (b) 7-NI (25 mg/kg, i.p.) followed by ethanol (4 g/kg, i.p.) 30 min later and (c) 7-NI (25 mg/kg, i.p.) followed by saline 30 min later. Untreated rats were used as controls. The concentrations of serum and intestinal IgA were measured by enzyme-linked immunosorbent assay, while the expression of nNOS was determined using western blot and immunohistochemistry. Acute ethanol treatment significantly increased the concentration of IgA in the ileal extracts, whereas it decreased its serum level. Inhibition of nNOS activity by 7-NI abolished this action of alcohol on IgA. Additionally, western blot analysis revealed that the acute alcohol administration induced an increase in the expression of intestinal nNOS. Furthermore, nNOS-immunoreactive cells, observed within the lamina propria of small intestine, were numerous in ethanol-treated rats. Taken together, these results extended our previous findings suggesting that nNOS mediates the acute effect of ethanol on IgA and supported an immunomodulatory role of this enzyme isoform.

Cassini/CIRS Observations of Saturn’s Polar Vortices from Proximal Orbit Observations

NASA Astrophysics Data System (ADS)

Achterberg, Richard; Bjoraker, Gordon L.; Hesman, Brigette E.; Flasar, F. Michael

2017-10-01

The proximal orbit phase of the Cassini mission, with periapses inside the inner edge of the rings, has allowed observations of Saturn’s atmosphere with unprecedented spatial resolution. During the periapse periods on 26 April and 29 June 2017, the Composite Infrared Spectrometer (CIRS) performed scans over both the north and south poles with a spatial resolution better than 0.2° of latitude, over a factor of 4 better resolution than previous observations. A further observation of the south pole is planned on 20 Aug 2017.Previous thermal infrared observations of Saturn’s poles [1,2] showed a compact hot spot in the upper troposphere at each pole, roughly coincident with the hurricane-like polar vortex seen in visible imaging [3]. Preliminary results from the proximal orbit scans of the north pole, near summer solstice, show that in the upper troposphere, the meridional temperature gradient increases sharply at about 89°N, with the temperature increasing by ~5K between 89°N and the pole, with the temperature gradient persisting all the way to the pole within the spatial resolution of the observation. In the northern stratosphere, the polar hot spot is broader than in the troposphere, extending to ~86°N at 4 mbar, and disappearing into the general meridional gradient at 1 mbar.[1] G. S. Orton and P. A. Yanamadra-Fisher, Science 307, 696[2] L. N. Fletcher et al., Science, 319, 79[3] U. A. Dyudina et al., Icarus, 202, 240.

Extended active disturbance rejection controller

NASA Technical Reports Server (NTRS)

Tian, Gang (Inventor); Gao, Zhiqiang (Inventor)

2012-01-01

Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

Extended Active Disturbance Rejection Controller

NASA Technical Reports Server (NTRS)

Gao, Zhiqiang (Inventor); Tian, Gang (Inventor)

2016-01-01

Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

Extended Active Disturbance Rejection Controller

NASA Technical Reports Server (NTRS)

Tian, Gang (Inventor); Gao, Zhiqiang (Inventor)

2014-01-01

Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

Optimization of the freeze-drying cycle: adaptation of the pressure rise analysis model to non-instantaneous isolation valves.

PubMed

Chouvenc, P; Vessot, S; Andrieu, J; Vacus, P

2005-01-01

The principal aim of this study is to extend to a pilot freeze-dryer equipped with a non-instantaneous isolation valve the previously presented pressure rise analysis (PRA) model for monitoring the product temperature and the resistance to mass transfer of the dried layer during primary drying. This method, derived from the original MTM method previously published, consists of interrupting rapidly (a few seconds) the water vapour flow from the sublimation chamber to the condenser and analysing the resulting dynamics of the total chamber pressure increase. The valve effect on the pressure rise profile observed during the isolation valve closing period was corrected by introducing in the initial PRA model a valve characteristic function factor which turned out to be independent of the operating conditions. This new extended PRA model was validated by implementing successively the two types of valves and by analysing the pressure rise kinetics data with the corresponding PRA models in the same operating conditions. The coherence and consistency shown on the identified parameter values (sublimation front temperature, dried layer mass transfer resistance) allowed validation of this extended PRA model with a non-instantaneous isolation valve. These results confirm that the PRA method, with or without an instantaneous isolation valve, is appropriate for on-line monitoring of product characteristics during freeze-drying. The advantages of PRA are that the method is rapid, non-invasive, and global. Consequently, PRA might become a powerful and promising tool not only for the control of pilot freeze-dryers but also for industrial freeze-dryers equipped with external condensers.

Saturation of the magnetorotational instability in the unstratified shearing box with zero net flux: convergence in taller boxes

NASA Astrophysics Data System (ADS)

Shi, Ji-Ming; Stone, James M.; Huang, Chelsea X.

2016-03-01

Previous studies of the non-linear regime of the magnetorotational instability in one particular type of shearing box model - unstratified with no net magnetic flux - find that without explicit dissipation (viscosity and resistivity) the saturation amplitude decreases with increasing numerical resolution. We show that this result is strongly dependent on the vertical aspect ratio of the computational domain Lz/Lx. When Lz/Lx ≲ 1, we recover previous results. However, when the vertical domain is extended Lz/Lx ≳ 2.5, we find the saturation level of the stress is greatly increased (giving a ratio of stress to pressure α ≳ 0.1), and moreover the results are independent of numerical resolution. Consistent with previous results, we find that saturation of the magnetorotational (MRI) in this regime is controlled by a cyclic dynamo which generates patches of strong toroidal field that switches sign on scales of Lx in the vertical direction. We speculate that when Lz/Lx ≲ 1, the dynamo is inhibited by the small size of the vertical domain, leading to the puzzling dependence of saturation amplitude on resolution. We show that previous toy models developed to explain the MRI dynamo are consistent with our results, and that the cyclic pattern of toroidal fields observed in stratified shearing box simulations (leading to the so-called butterfly diagram) may also be related. In tall boxes the saturation amplitude is insensitive to whether or not explicit dissipation is included in the calculations, at least for large magnetic Reynolds and Prandtl number. Finally, we show MRI turbulence in tall domains has a smaller critical Pmc, and an extended lifetime compared to Lz/Lx ≲ 1 boxes.

Spitzer Observations of GRB Hosts: A Legacy Approach

NASA Astrophysics Data System (ADS)

Perley, Daniel; Tanvir, Nial; Hjorth, Jens; Berger, Edo; Laskar, Tanmoy; Michalowski, Michal; Chary, Ranga-Ram; Fynbo, Johan; Levan, Andrew

2012-09-01

The host galaxies of long-duration GRBs are drawn from uniquely broad range of luminosities and redshifts. Thus they offer the possibility of studying the evolution of star-forming galaxies without the limitations of other luminosity-selected samples, which typically are increasingly biased towards the most massive systems at higher redshift. However, reaping the full benefits of this potential requires careful attention to the selection biases affecting host identification. To this end, we propose observations of a Legacy sample of 70 GRB host galaxies (an additional 70 have already been observed by Spitzer), in order to constrain the mass and luminosity function in GRB-selected galaxies at high redshift, including its dependence on redshift and on properties of the afterglow. Crucially, and unlike previous Spitzer surveys, this sample is carefully designed to be uniform and free of optical selection biases that have caused previous surveys to systematically under-represent the role of luminous, massive hosts. We also propose to extend to larger, more powerfully constraining samples the study of two science areas where Spitzer observations have recently shown spectacular success: the hosts of dust-obscured GRBs (which promise to further our understanding of the connection between GRBs and star-formation in the most luminous galaxies), and the evolution of the mass-metallicity relation at z>2 (for which GRB host observations provide particularly powerful constraints on high-z chemical evolution).

Raman signature of the non-hydrogen-bonded tryptophan side chain in proteins: experimental and ab initio spectra of 3-methylindole in the gas phase

NASA Astrophysics Data System (ADS)

Combs, Amanda; McCann, Kathleen; Autrey, Daniel; Laane, Jaan; Overman, Stacy A.; Thomas, George J.

2005-02-01

3-Methylindole (3MI), which serves as a structural model for the tryptophan side chain in proteins, has been investigated using vapor phase Raman spectroscopy. The vapor phase spectrum of 3MI identifies the Raman signature of the indolyl moiety free of intermolecular interaction and extends previously reported solution Raman studies of 3MI and related tryptophan derivatives. The Raman spectrum of 3MI vapor is also complemented here with newly obtained vapor phase infrared data and ab initio calculations to refine and extend previous vibrational assignments. The present results provide an improved basis for assessing the dependence of the indolyl Raman signature on the local environment of the tryptophan side chain of proteins. The principal conclusions of this work are the following. (i) The vapor phase 3MI molecule exhibits Raman bands at 3506, 1585, 1409, 1349/1341 (Fermi doublet) and 881 cm-1, which differ greatly from their counterparts in the Raman spectrum of 3MI liquid and thus serve as spectral markers of the indolyl ring environment. (ii) The Fermi doublet relative intensity ratio (I1/I2, where I1 and I2 are, respectively, the Raman intensities of the higher and lower wavenumber components of the doublet) is highly sensitive to the state of 3MI condensation, consistent with the previously reported sensitivity of I1/I2 to solvent polarity. The maximum value of the intensity ratio (I1/I2=3.0) is observed for 3MI vapor, while the minimum value (I1/I2=0.43) is observed for 3MI in CHCl3 solution. Implications of the present results for Raman analysis of hydrogen bonding states, hydrophilic interactions and hydrophobic interactions of tryptophan residues in proteins are considered.

Kinematic activity of gray wolf (Canis lupus) sperm in different extenders, added before or after centrifugation.

PubMed

Christensen, Bruce W; Asa, Cheryl S; Wang, Chong; Bauman, Karen; Agnew, Mary K; Lorton, Steven P; Callahan, Margaret

2013-04-01

We evaluated two approaches to improving in vitro wolf sperm survival. Both approaches aimed to reduce the exposure of sperm to prostatic fluid resulting from electroejaculation: (1) use of extender formulations recently developed for the domestic dog (the most closely related domestic species); and (2) dilution of ejaculate shortly after semen collection. Three commercial extenders were compared with the TRIS-based extender we had previously used. We also compared the effects on motility of adding extender immediately after collection to our previous protocol in which extender was added after centrifugation. Both subjective and objective (computer-assisted semen analysis program) kinematic measurements were made. Relatively minor differences were noted (and not in total or progressive motility) between the centrifugation protocols. Two of the commercial extenders resulted in significant improvement in motility over the TRIS-based extender and one of the other commercial extenders at 8 hours after collection (mean ± SEM; total motility was 68.3 ± 4.0% and 70.0 ± 4.0% compared with 53.3 ± 4.0% and 55.0 ± 4.0%, respectively; progressive motility 58.6 ± 5.4% and 57.1 ± 5.4% compared with 32.8 ± 5.4% and 39.3 ± 5.4%; P < 0.05). We inferred that components in two of the commercial dog extenders might provide more protection for wolf sperm, prolonging their motility. Copyright © 2013 Elsevier Inc. All rights reserved.

Color-magnitude Diagrams for the Stellar Open Cluster M 67 in theVilnius Photometric System

NASA Astrophysics Data System (ADS)

Boyle, Richard P.; Janusz, Robert

2015-01-01

Stellar photometry in the Vilnius Photometric System requires one percent quality for deriving luminosity class and spectral type subclass. We use such existing photometry of the open cluster M 67 to calibrate new CCD observations at the Vatican Advanced Technology Telescope (VATT) for correcting the flat-fielding zero-point and deriving the color-transformation in this intermediate-band, seven filter system (Boyle et al., BAAS 37 #4, 2005).Recently we have developed a "tie-in" observational practice to apply the zero-point and color transformation of the M 67 observations to neighboring starfields of interest that have no existing photometry. Sky transparency must remain constant to better than one percent during a round of short exposures in a filter between the field having calibrated photometry and the new field having no photometry as if the new field was exposed simultaneously with the master field.Proof of success for this "tie-in" method is shown with the master field being M 67 and the "tie-in" field being the nearby extended "corona" area. The distinctive color-magnitude diagrams of the old open clusterM 67 reveal the sensitivity to having constant sky transparency during the round of short exposures on M 67 and its extended area. For the extended area has the same form in its color-magnitude diagram as M 67. So variation in sky transparency shows displacement on the color-magnitude diagrams at the one percent quality.We will attempt new analysis concerning evolution of this very old open cluster (2.56 Gyr, WEBDA, http://www.univie.ac.at/webda/) and the surrounding "coronal" extent with reference to previous work by Chupina and Vereshchagin (Astron. Astrophys, 334, 552, 1998).

Stimulus-response correspondence effect as a function of temporal overlap between relevant and irrelevant information processing.

PubMed

Wang, Dong-Yuan Debbie; Richard, F Dan; Ray, Brittany

2016-01-01

The stimulus-response correspondence (SRC) effect refers to advantages in performance when stimulus and response correspond in dimensions or features, even if the common features are irrelevant to the task. Previous research indicated that the SRC effect depends on the temporal course of stimulus information processing. The current study investigated how the temporal overlap between relevant and irrelevant stimulus processing influences the SRC effect. In this experiment, the irrelevant stimulus (a previously associated tone) preceded the relevant stimulus (a coloured rectangle). The irrelevant and relevant stimuli onset asynchrony was varied to manipulate the temporal overlap between the irrelevant and relevant stimuli processing. Results indicated that the SRC effect size varied as a quadratic function of the temporal overlap between the relevant stimulus and irrelevant stimulus. This finding extends previous experimental observations that the SRC effect size varies in an increasing or decreasing function with reaction time. The current study demonstrated a quadratic function between effect size and the temporal overlap.

The politics of insight

PubMed Central

Salvi, Carola; Cristofori, Irene; Grafman, Jordan; Beeman, Mark

2016-01-01

Previous studies showed that liberals and conservatives differ in cognitive style. Liberals are more flexible, and tolerant of complexity and novelty, whereas conservatives are more rigid, are more resistant to change, and prefer clear answers. We administered a set of compound remote associate problems, a task extensively used to differentiate problem-solving styles (via insight or analysis). Using this task, several researches have proven that self-reports, which differentiate between insight and analytic problem-solving, are reliable and are associated with two different neural circuits. In our research we found that participants self-identifying with distinct political orientations demonstrated differences in problem-solving strategy. Liberals solved significantly more problems via insight instead of in a step-by-step analytic fashion. Our findings extend previous observations that self-identified political orientations reflect differences in cognitive styles. More specifically, we show that type of political orientation is associated with problem-solving strategy. The data converge with previous neurobehavioural and cognitive studies indicating a link between cognitive style and the psychological mechanisms that mediate political beliefs. PMID:26810954

The politics of insight.

PubMed

Salvi, Carola; Cristofori, Irene; Grafman, Jordan; Beeman, Mark

2016-01-01

Previous studies showed that liberals and conservatives differ in cognitive style. Liberals are more flexible, and tolerant of complexity and novelty, whereas conservatives are more rigid, are more resistant to change, and prefer clear answers. We administered a set of compound remote associate problems, a task extensively used to differentiate problem-solving styles (via insight or analysis). Using this task, several researches have proven that self-reports, which differentiate between insight and analytic problem-solving, are reliable and are associated with two different neural circuits. In our research we found that participants self-identifying with distinct political orientations demonstrated differences in problem-solving strategy. Liberals solved significantly more problems via insight instead of in a step-by-step analytic fashion. Our findings extend previous observations that self-identified political orientations reflect differences in cognitive styles. More specifically, we show that type of political orientation is associated with problem-solving strategy. The data converge with previous neurobehavioural and cognitive studies indicating a link between cognitive style and the psychological mechanisms that mediate political beliefs.

Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in Adults

PubMed Central

Yang, Xiaoxia; Duan, John; Fisher, Jeffrey

2016-01-01

A previously presented physiologically-based pharmacokinetic model for immediate release (IR) methylphenidate (MPH) was extended to characterize the pharmacokinetic behaviors of oral extended release (ER) MPH formulations in adults for the first time. Information on the anatomy and physiology of the gastrointestinal (GI) tract, together with the biopharmaceutical properties of MPH, was integrated into the original model, with model parameters representing hepatic metabolism and intestinal non-specific loss recalibrated against in vitro and in vivo kinetic data sets with IR MPH. A Weibull function was implemented to describe the dissolution of different ER formulations. A variety of mathematical functions can be utilized to account for the engineered release/dissolution technologies to achieve better model performance. The physiological absorption model tracked well the plasma concentration profiles in adults receiving a multilayer-release MPH formulation or Metadate CD, while some degree of discrepancy was observed between predicted and observed plasma concentration profiles for Ritalin LA and Medikinet Retard. A local sensitivity analysis demonstrated that model parameters associated with the GI tract significantly influenced model predicted plasma MPH concentrations, albeit to varying degrees, suggesting the importance of better understanding the GI tract physiology, along with the intestinal non-specific loss of MPH. The model provides a quantitative tool to predict the biphasic plasma time course data for ER MPH, helping elucidate factors responsible for the diverse plasma MPH concentration profiles following oral dosing of different ER formulations. PMID:27723791

What’s in a Name? Sound Symbolism and Gender in First Names

PubMed Central

2015-01-01

Although the arbitrariness of language has been considered one of its defining features, studies have demonstrated that certain phonemes tend to be associated with certain kinds of meaning. A well-known example is the Bouba/Kiki effect, in which nonwords like bouba are associated with round shapes while nonwords like kiki are associated with sharp shapes. These sound symbolic associations have thus far been limited to nonwords. Here we tested whether or not the Bouba/Kiki effect extends to existing lexical stimuli; in particular, real first names. We found that the roundness/sharpness of the phonemes in first names impacted whether the names were associated with round or sharp shapes in the form of character silhouettes (Experiments 1a and 1b). We also observed an association between femaleness and round shapes, and maleness and sharp shapes. We next investigated whether this association would extend to the features of language and found the proportion of round-sounding phonemes was related to name gender (Analysis of Category Norms). Finally, we investigated whether sound symbolic associations for first names would be observed for other abstract properties; in particular, personality traits (Experiment 2). We found that adjectives previously judged to be either descriptive of a figuratively ‘round’ or a ‘sharp’ personality were associated with names containing either round- or sharp-sounding phonemes, respectively. These results demonstrate that sound symbolic associations extend to existing lexical stimuli, providing a new example of non-arbitrary mappings between form and meaning. PMID:26016856

What's in a Name? Sound Symbolism and Gender in First Names.

PubMed

Sidhu, David M; Pexman, Penny M

2015-01-01

Although the arbitrariness of language has been considered one of its defining features, studies have demonstrated that certain phonemes tend to be associated with certain kinds of meaning. A well-known example is the Bouba/Kiki effect, in which nonwords like bouba are associated with round shapes while nonwords like kiki are associated with sharp shapes. These sound symbolic associations have thus far been limited to nonwords. Here we tested whether or not the Bouba/Kiki effect extends to existing lexical stimuli; in particular, real first names. We found that the roundness/sharpness of the phonemes in first names impacted whether the names were associated with round or sharp shapes in the form of character silhouettes (Experiments 1a and 1b). We also observed an association between femaleness and round shapes, and maleness and sharp shapes. We next investigated whether this association would extend to the features of language and found the proportion of round-sounding phonemes was related to name gender (Analysis of Category Norms). Finally, we investigated whether sound symbolic associations for first names would be observed for other abstract properties; in particular, personality traits (Experiment 2). We found that adjectives previously judged to be either descriptive of a figuratively 'round' or a 'sharp' personality were associated with names containing either round- or sharp-sounding phonemes, respectively. These results demonstrate that sound symbolic associations extend to existing lexical stimuli, providing a new example of non-arbitrary mappings between form and meaning.

Periodicity of Strong Seismicity in Italy: Schuster Spectrum Analysis Extended to the Destructive Earthquakes of 2016

NASA Astrophysics Data System (ADS)

Bragato, P. L.

2017-10-01

The strong earthquakes that occurred in Italy between 2009 and 2016 represent an abrupt acceleration of seismicity in respect of the previous 30 years. Such behavior seems to agree with the periodic rate change I observed in a previous paper. The present work improves that study by extending the data set up to the end of 2016, adopting the latest version of the historical seismic catalog of Italy, and introducing Schuster spectrum analysis for the detection of the oscillatory period and the assessment of its statistical significance. Applied to the declustered catalog of M w ≥ 6 earthquakes that occurred between 1600 and 2016, the analysis individuates a marked periodicity of 46 years, which is recognized above the 95% confidence level. Monte Carlo simulation shows that the oscillatory behavior is stable in respect of random errors on magnitude estimation. A parametric oscillatory model for the annual rate of seismicity is estimated by likelihood maximization under the hypothesis of inhomogeneous Poisson point process. According to the Akaike Information Criterion, such model outperforms the simpler homogeneous one with constant annual rate. A further element emerges form the analysis: so far, despite recent earthquakes, the Italian seismicity is still within a long-term decreasing trend established since the first half of the twentieth century.

Gibberellins Are Required for Seed Development and Pollen Tube Growth in Arabidopsis

PubMed Central

Singh, Davinder P.; Jermakow, Angelica M.; Swain, Stephen M.

2002-01-01

Gibberellins (GAs) are tetracyclic diterpenoids that are essential endogenous regulators of plant growth and development. GA levels within the plant are regulated by a homeostatic mechanism that includes changes in the expression of a family of GA-inactivating enzymes known as GA 2-oxidases. Ectopic expression of a pea GA 2-oxidase2 cDNA caused seed abortion in Arabidopsis, extending and confirming previous observations obtained with GA-deficient mutants of pea, suggesting that GAs have an essential role in seed development. A new physiological role for GAs in pollen tube growth in vivo also has been identified. The growth of pollen tubes carrying the 35S:2ox2 transgene was reduced relative to that of nontransgenic pollen, and this phenotype could be reversed partially by GA application in vitro or by combining with spy-5, a mutation that increases GA response. Treatment of wild-type pollen tubes with an inhibitor of GA biosynthesis in vitro also suggested that GAs are required for normal pollen tube growth. These results extend the known physiological roles of GAs in Arabidopsis development and suggest that GAs are required for normal pollen tube growth, a physiological role for GAs that has not been established previously. PMID:12468732

Extending Structural Analyses of the Rosenberg Self-Esteem Scale to Consider Criterion-Related Validity: Can Composite Self-Esteem Scores Be Good Enough?

PubMed

Donnellan, M Brent; Ackerman, Robert A; Brecheen, Courtney

2016-01-01

Although the Rosenberg Self-Esteem Scale (RSES) is the most widely used measure of global self-esteem in the literature, there are ongoing disagreements about its factor structure. This methodological debate informs how the measure should be used in substantive research. Using a sample of 1,127 college students, we test the overall fit of previously specified models for the RSES, including a newly proposed bifactor solution (McKay, Boduszek, & Harvey, 2014 ). We extend previous work by evaluating how various latent factors from these structural models are related to a set of criterion variables frequently studied in the self-esteem literature. A strict unidimensional model poorly fit the data, whereas models that accounted for correlations between negatively and positively keyed items tended to fit better. However, global factors from viable structural models had similar levels of association with criterion variables and with the pattern of results obtained with a composite global self-esteem variable calculated from observed scores. Thus, we did not find compelling evidence that different structural models had substantive implications, thereby reducing (but not eliminating) concerns about the integrity of the self-esteem literature based on overall composite scores for the RSES.

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooper, Jonathan B.; Weiss, Kevin L.; Coates, Leighton

The monobactam antibiotic aztreonam is used to treat cystic fibrosis patients with chronic pulmonary infections colonized by Pseudomonas aeruginosa strains expressing CTX-M extended-spectrum β-lactamases. Several active site residues in class A β-lactamases have been proposed to play key roles in monobactam hydrolysis. The protonation states of these residues have been determined previously for the apo form of a CTX-M β-lactamase. However, they have not yet been determined for a monobactam acyl-enzyme intermediate. Here we used neutron and high-resolution X-ray crystallography to probe the mechanism by which CTX-M extended-spectrum β-lactamases hydrolyze monobactam antibiotics. In these first reported structures of a classmore » A β-lactamase in acyl enzyme complex with aztreonam we directly observed most of the hydrogen atoms (as deuterium) within the active site in the captured acyl-enzyme state between Toho-1 β-lactamase and aztreonam. Although Lys 234 is fully protonated in the acyl-intermediate, we find that Lys 73 is neutral. These findings are consistent with Lys 73 being able to serve as a general base during the acylation part of the catalytic mechanism, in agreement with previous mechanistic proposals.« less

Terminal Schwann Cells Participate in Neuromuscular Synapse Remodeling during Reinnervation following Nerve Injury

PubMed Central

Kang, Hyuno; Tian, Le; Mikesh, Michelle; Lichtman, Jeff W.

2014-01-01

Schwann cells (SCs) at neuromuscular junctions (NMJs) play active roles in synaptic homeostasis and repair. We have studied how SCs contribute to reinnervation of NMJs using vital imaging of mice whose motor axons and SCs are transgenically labeled with different colors of fluorescent proteins. Motor axons most commonly regenerate to the original synaptic site by following SC-filled endoneurial tubes. During the period of denervation, SCs at the NMJ extend elaborate processes from the junction, as shown previously, but they also retract some processes from territory they previously occupied within the endplate. The degree of this retraction depends on the length of the period of denervation. We show that the topology of the remaining SC processes influences the branching pattern of regenerating axon terminals and the redistribution of acetylcholine receptors (AChRs). Upon arriving at the junction, regenerating axons follow existing SC processes within the old synaptic site. Some of the AChR loss that follows denervation is correlated with failure of portions of the old synaptic site that lack SC coverage to be reinnervated. New AChR clustering is also induced by axon terminals that follow SC processes extended during denervation. These observations show that SCs participate actively in the remodeling of neuromuscular synapses following nerve injury by their guidance of axonal reinnervation. PMID:24790203

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate

DOE PAGES

Cooper, Jonathan B.; Weiss, Kevin L.; Coates, Leighton; ...

2016-10-24

The monobactam antibiotic aztreonam is used to treat cystic fibrosis patients with chronic pulmonary infections colonized by Pseudomonas aeruginosa strains expressing CTX-M extended-spectrum β-lactamases. Several active site residues in class A β-lactamases have been proposed to play key roles in monobactam hydrolysis. The protonation states of these residues have been determined previously for the apo form of a CTX-M β-lactamase. However, they have not yet been determined for a monobactam acyl-enzyme intermediate. Here we used neutron and high-resolution X-ray crystallography to probe the mechanism by which CTX-M extended-spectrum β-lactamases hydrolyze monobactam antibiotics. In these first reported structures of a classmore » A β-lactamase in acyl enzyme complex with aztreonam we directly observed most of the hydrogen atoms (as deuterium) within the active site in the captured acyl-enzyme state between Toho-1 β-lactamase and aztreonam. Although Lys 234 is fully protonated in the acyl-intermediate, we find that Lys 73 is neutral. These findings are consistent with Lys 73 being able to serve as a general base during the acylation part of the catalytic mechanism, in agreement with previous mechanistic proposals.« less

The new Be-type star HD 147196 in the Rho Ophiuchi dark cloud region

NASA Technical Reports Server (NTRS)

The, P. S.; Perez, M. R.; De Winter, D.; Van Den Ancker, M. E.

1993-01-01

The newly discovered hot-emission line star, HD 147196 in the Rho Oph dark cloud region was observed spectroscopically and photometrically and high and low resolution IUE spectra were obtained. The finding of Irvine (1990) that this relatively bright star show its H-alpha-line in emission is confirmed. Previous H-alpha-surveys of the Rho Oph star-forming region did not detect HD 147196 as an H-alpha-emission star, meaning that it must recently be very active and has perhaps transformed itself from a B-type star at shell phase to a Be-phase. The Mg II h + k resonance lines are in absorption and they appear to be interstellar in nature, which means that either the abundance of Mg in the extended atmosphere of the star is low or that the shell is not extended enough to produce emission lines of Mg II. Photometric observations of this B8 V type star do not show any variations during at least the years covered by our monitoring or any excess of NIR radiation in its spectral energy distribution up to the M-passband at 4.8 microns.

A first determination of the surface density of galaxy clusters at very low x-ray fluxes

NASA Technical Reports Server (NTRS)

Rosati, Piero; Della Ceca, Roberta; Burg, Richard; Norman, Colin; Giacconi, Riccardo

1995-01-01

We present the first results of a serendipitous search for clusters of galaxies in deep ROSAT position sensitive proportional counter (PSPC) pointed observations at high Galactic latitude. The survey is being carried out using a wavelet-based detection algorithm which is not biased against extended, low surface brightness sources. A new flux-diameter limited sample of 10 cluster candidates has been created from approximately 3 deg(exp 2) surveyed area. Preliminary CCD observations have revealed that a large fraction of these candidates correspond to a visible enhancement in the galaxy surface density, and several others have been identified from other surveys. We believe these sources to be either low- to moderate-redshift groups or intermediate- to high-redshift clusters. We show X-ray and optical images of some of the clusters identified to date. We present, for the first time, the derived number density of the galaxy clusters to a flux limit of 1 x 10(exp -14) ergs cm(exp -2) s(exp -1) (0.5-2.0 keV). This extends the log N-log S of previous cluster surveys by more than one decade in flux. Results are compared to theoretical predictions for cluster number counts.

A Linearized Model for Flicker and Contrast Thresholds at Various Retinal Illuminances

NASA Technical Reports Server (NTRS)

Ahumada, Albert; Watson, Andrew

2015-01-01

We previously proposed a flicker visibility metric for bright displays, based on psychophysical data collected at a high mean luminance. Here we extend the metric to other mean luminances. This extension relies on a linear relation between log sensitivity and critical fusion frequency, and a linear relation between critical fusion frequency and log retina lilluminance. Consistent with our previous metric, the extended flicker visibility metric is measured in just-noticeable differences (JNDs).

Hemispheric Asymmetries in Substorm Recovery Time Scales

NASA Technical Reports Server (NTRS)

Fillingim, M. O.; Chua, D H.; Germany, G. A.; Spann, James F.

2009-01-01

Previous statistical observations have shown that the recovery time scales of substorms occurring in the winter and near equinox (when the nighttime auroral zone was in darkness) are roughly twice as long as the recovery time scales for substorms occurring in the summer (when the nighttime auroral region was sunlit). This suggests that auroral substorms in the northern and southern hemispheres develop asymmetrically during solstice conditions with substorms lasting longer in the winter (dark) hemisphere than in the summer (sunlit) hemisphere. Additionally, this implies that more energy is deposited by electron precipitation in the winter hemisphere than in the summer one during substorms. This result, coupled with previous observations that have shown that auroral activity is more common when the ionosphere is in darkness and is suppressed when the ionosphere is in daylight, strongly suggests that the ionospheric conductivity plays an important role governing how magnetospheric energy is transferred to the ionosphere during substorms. Therefore, the ionosphere itself may dictate how much energy it will accept from the magnetosphere during substorms rather than this being an externally imposed quantity. Here, we extend our earlier work by statistically analyzing the recovery time scales for a large number of substorms observed in the conjugate hemispheres simultaneously by two orbiting global auroral imagers: Polar UVI and IMAGE FUV. Our current results are consistent with previous observations. The recovery time scales are observed to be longer in the winter (dark) hemisphere while the auroral activity has a shorter duration in the summer (sunlit) hemisphere. This leads to an asymmetric energy input from the magnetosphere to the ionosphere with more energy being deposited in the winter hemisphere than in the summer hemisphere.

Probing sub-GeV dark matter-baryon scattering with cosmological observables

NASA Astrophysics Data System (ADS)

Xu, Weishuang Linda; Dvorkin, Cora; Chael, Andrew

2018-05-01

We derive new limits on the elastic scattering cross section between baryons and dark matter using cosmic microwave background data from the Planck satellite and measurements of the Lyman-alpha forest flux power spectrum from the Sloan Digital Sky Survey. Our analysis addresses generic cross sections of the form σ ∝vn , where v is the dark matter-baryon relative velocity, allowing for constraints on the cross section independent of specific particle physics models. We include high-ℓ polarization data from Planck in our analysis, improving over previous constraints. We apply a more careful treatment of dark matter thermal evolution than previously done, allowing us to extend our constraints down to dark matter masses of ˜MeV . We show in this work that cosmological probes are complementary to current direct detection and astrophysical searches.

Nonlinear regimes on polygonal hydraulic jumps

NASA Astrophysics Data System (ADS)

Rojas, Nicolas

2016-11-01

This work extends previous leading and higher order results on the polygonal hydraulic jump in the framework of inertial lubrication theory. The rotation of steady polygonal jumps is observed in the transition from one wavenumber to the next one, induced by a change in height of an external obstacle near the outer edge. In a previous publication, the study of stationary polygons is considered under the assumption that the reference frame rotates with the polygons when the number of corners change, in order to preserve their orientation. In this research work I provide a Hamiltonian approach and the stability analysis of the nonlinear oscillator that describe the polygonal structures at the jump interface, in addition to a perturbation method that enables to explain, for instance, the diversity of patterns found in experiments. GRASP, Institute of Physics, University of Liege, Belgium.

H.E.S.S. Limits on Linelike Dark Matter Signatures in the 100 GeV to 2 TeV Energy Range Close to the Galactic Center.

PubMed

Abdalla, H; Abramowski, A; Aharonian, F; Ait Benkhali, F; Akhperjanian, A G; Andersson, T; Angüner, E O; Arrieta, M; Aubert, P; Backes, M; Balzer, A; Barnard, M; Becherini, Y; Becker Tjus, J; Berge, D; Bernhard, S; Bernlöhr, K; Birsin, E; Blackwell, R; Böttcher, M; Boisson, C; Bolmont, J; Bordas, P; Bregeon, J; Brun, F; Brun, P; Bryan, M; Bulik, T; Capasso, M; Carr, J; Casanova, S; Chakraborty, N; Chalme-Calvet, R; Chaves, R C G; Chen, A; Chevalier, J; Chrétien, M; Colafrancesco, S; Cologna, G; Condon, B; Conrad, J; Couturier, C; Cui, Y; Davids, I D; Degrange, B; Deil, C; Devin, J; deWilt, P; Djannati-Ataï, A; Domainko, W; Donath, A; Drury, L O'C; Dubus, G; Dutson, K; Dyks, J; Dyrda, M; Edwards, T; Egberts, K; Eger, P; Ernenwein, J-P; Eschbach, S; Farnier, C; Fegan, S; Fernandes, M V; Fiasson, A; Fontaine, G; Förster, A; Funk, S; Füßling, M; Gabici, S; Gajdus, M; Gallant, Y A; Garrigoux, T; Giavitto, G; Giebels, B; Glicenstein, J F; Gottschall, D; Goyal, A; Grondin, M-H; Grudzińska, M; Hadasch, D; Hahn, J; Hawkes, J; Heinzelmann, G; Henri, G; Hermann, G; Hervet, O; Hillert, A; Hinton, J A; Hofmann, W; Hoischen, C; Holler, M; Horns, D; Ivascenko, A; Jacholkowska, A; Jamrozy, M; Janiak, M; Jankowsky, D; Jankowsky, F; Jingo, M; Jogler, T; Jouvin, L; Jung-Richardt, I; Kastendieck, M A; Katarzyński, K; Katz, U; Kerszberg, D; Khélifi, B; Kieffer, M; King, J; Klepser, S; Klochkov, D; Kluźniak, W; Kolitzus, D; Komin, Nu; Kosack, K; Krakau, S; Kraus, M; Krayzel, F; Krüger, P P; Laffon, H; Lamanna, G; Lau, J; Lees, J-P; Lefaucheur, J; Lefranc, V; Lemière, A; Lemoine-Goumard, M; Lenain, J-P; Leser, E; Liu, R; Lohse, T; Lorentz, M; Lypova, I; Marandon, V; Marcowith, A; Mariaud, C; Marx, R; Maurin, G; Maxted, N; Mayer, M; Meintjes, P J; Meyer, M; Mitchell, A M W; Moderski, R; Mohamed, M; Morå, K; Moulin, E; Murach, T; de Naurois, M; Niederwanger, F; Niemiec, J; Oakes, L; O'Brien, P; Odaka, H; Ohm, S; Ostrowski, M; Öttl, S; Oya, I; Padovani, M; Panter, M; Parsons, R D; Paz Arribas, M; Pekeur, N W; Pelletier, G; Perennes, C; Petrucci, P-O; Peyaud, B; Pita, S; Poon, H; Prokhorov, D; Prokoph, H; Pühlhofer, G; Punch, M; Quirrenbach, A; Raab, S; Reimer, A; Reimer, O; Renaud, M; de Los Reyes, R; Rieger, F; Romoli, C; Rosier-Lees, S; Rowell, G; Rudak, B; Rulten, C B; Sahakian, V; Salek, D; Sanchez, D A; Santangelo, A; Sasaki, M; Schlickeiser, R; Schüssler, F; Schulz, A; Schwanke, U; Schwemmer, S; Settimo, M; Seyffert, A S; Shafi, N; Shilon, I; Simoni, R; Sol, H; Spanier, F; Spengler, G; Spies, F; Stawarz, Ł; Steenkamp, R; Stegmann, C; Stinzing, F; Stycz, K; Sushch, I; Tavernet, J-P; Tavernier, T; Taylor, A M; Terrier, R; Tibaldo, L; Tluczykont, M; Trichard, C; Tuffs, R; van der Walt, J; van Eldik, C; van Soelen, B; Vasileiadis, G; Veh, J; Venter, C; Viana, A; Vincent, P; Vink, J; Voisin, F; Völk, H J; Vuillaume, T; Wadiasingh, Z; Wagner, S J; Wagner, P; Wagner, R M; White, R; Wierzcholska, A; Willmann, P; Wörnlein, A; Wouters, D; Yang, R; Zabalza, V; Zaborov, D; Zacharias, M; Zdziarski, A A; Zech, A; Zefi, F; Ziegler, A; Żywucka, N

2016-10-07

A search for dark matter linelike signals iss performed in the vicinity of the Galactic Center by the H.E.S.S. experiment on observational data taken in 2014. An unbinned likelihood analysis iss developed to improve the sensitivity to linelike signals. The upgraded analysis along with newer data extend the energy coverage of the previous measurement down to 100 GeV. The 18 h of data collected with the H.E.S.S. array allow one to rule out at 95% C.L. the presence of a 130 GeV line (at l=-1.5°, b=0° and for a dark matter profile centered at this location) previously reported in Fermi-LAT data. This new analysis overlaps significantly in energy with previous Fermi-LAT and H.E.S.S. No significant excess associated with dark matter annihilations was found in the energy range of 100 GeV to 2 TeV and upper limits on the gamma-ray flux and the velocity weighted annihilation cross section are derived adopting an Einasto dark matter halo profile. Expected limits for present and future large statistics H.E.S.S. observations are also given.

H.E.S.S. Limits on Linelike Dark Matter Signatures in the 100 GeV to 2 TeV Energy Range Close to the Galactic Center

NASA Astrophysics Data System (ADS)

Abdalla, H.; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Andersson, T.; Angüner, E. O.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Becker Tjus, J.; Berge, D.; Bernhard, S.; Bernlöhr, K.; Birsin, E.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Couturier, C.; Cui, Y.; Davids, I. D.; Degrange, B.; Deil, C.; Devin, J.; deWilt, P.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O'C.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Grudzińska, M.; Hadasch, D.; Hahn, J.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kerszberg, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Kraus, M.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Liu, R.; Lohse, T.; Lorentz, M.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Morâ, K.; Moulin, E.; Murach, T.; de Naurois, M.; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Ohm, S.; Ostrowski, M.; Öttl, S.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tluczykont, M.; Trichard, C.; Tuffs, R.; van der Walt, J.; van Eldik, C.; van Soelen, B.; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Żywucka, N.; H. E. S. S. Collaboration

2016-10-01

A search for dark matter linelike signals iss performed in the vicinity of the Galactic Center by the H.E.S.S. experiment on observational data taken in 2014. An unbinned likelihood analysis iss developed to improve the sensitivity to linelike signals. The upgraded analysis along with newer data extend the energy coverage of the previous measurement down to 100 GeV. The 18 h of data collected with the H.E.S.S. array allow one to rule out at 95% C.L. the presence of a 130 GeV line (at l =-1.5 ° , b =0 ° and for a dark matter profile centered at this location) previously reported in Fermi-LAT data. This new analysis overlaps significantly in energy with previous Fermi-LAT and H.E.S.S. results. No significant excess associated with dark matter annihilations was found in the energy range of 100 GeV to 2 TeV and upper limits on the gamma-ray flux and the velocity weighted annihilation cross section are derived adopting an Einasto dark matter halo profile. Expected limits for present and future large statistics H.E.S.S. observations are also given.

Building an Open-source Simulation Platform of Acoustic Radiation Force-based Breast Elastography

PubMed Central

Wang, Yu; Peng, Bo; Jiang, Jingfeng

2017-01-01

Ultrasound-based elastography including strain elastography (SE), acoustic radiation force Impulse (ARFI) imaging, point shear wave elastography (pSWE) and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published virtual simulation platform built for ultrasound quasi-static breast elastography toward acoustic radiation force-based breast elastography. Consequently, the extended virtual breast elastography simulation platform can be used to validate image pixels with known underlying soft tissue properties (i.e. “ground truth”) in complex, heterogeneous media, enhancing confidence in elastographic image interpretations. The proposed virtual breast elastography system inherited four key components from the previously published virtual simulation platform: an ultrasound simulator (Field II), a mesh generator (Tetgen), a finite element solver (FEBio) and a visualization and data processing package (VTK). Using a simple message passing mechanism, functionalities have now been extended to acoustic radiation force-based elastography simulations. Examples involving three different numerical breast models with increasing complexity – one uniform model, one simple inclusion model and one virtual complex breast model derived from magnetic resonance imaging data, were used to demonstrate capabilities of this extended virtual platform. Overall, simulation results were compared with the published results. In the uniform model, the estimated shear wave speed (SWS) values were within 4% compared to the predetermined SWS values. In the simple inclusion and the complex breast models, SWS values of all hard inclusions in soft backgrounds were slightly underestimated, similar to what has been reported. The elastic contrast values and visual observation show that ARFI images have higher spatial resolution, while SSI images can provide higher inclusion-to-background contrast. In summary, our initial results were consistent with our expectations and what have been reported in the literature. The proposed (open-source) simulation platform can serve as a single gateway to perform many elastographic simulations in a transparent manner, thereby promoting collaborative developments. PMID:28075330

Building an open-source simulation platform of acoustic radiation force-based breast elastography

NASA Astrophysics Data System (ADS)

Wang, Yu; Peng, Bo; Jiang, Jingfeng

2017-03-01

Ultrasound-based elastography including strain elastography, acoustic radiation force impulse (ARFI) imaging, point shear wave elastography and supersonic shear imaging (SSI) have been used to differentiate breast tumors among other clinical applications. The objective of this study is to extend a previously published virtual simulation platform built for ultrasound quasi-static breast elastography toward acoustic radiation force-based breast elastography. Consequently, the extended virtual breast elastography simulation platform can be used to validate image pixels with known underlying soft tissue properties (i.e. ‘ground truth’) in complex, heterogeneous media, enhancing confidence in elastographic image interpretations. The proposed virtual breast elastography system inherited four key components from the previously published virtual simulation platform: an ultrasound simulator (Field II), a mesh generator (Tetgen), a finite element solver (FEBio) and a visualization and data processing package (VTK). Using a simple message passing mechanism, functionalities have now been extended to acoustic radiation force-based elastography simulations. Examples involving three different numerical breast models with increasing complexity—one uniform model, one simple inclusion model and one virtual complex breast model derived from magnetic resonance imaging data, were used to demonstrate capabilities of this extended virtual platform. Overall, simulation results were compared with the published results. In the uniform model, the estimated shear wave speed (SWS) values were within 4% compared to the predetermined SWS values. In the simple inclusion and the complex breast models, SWS values of all hard inclusions in soft backgrounds were slightly underestimated, similar to what has been reported. The elastic contrast values and visual observation show that ARFI images have higher spatial resolution, while SSI images can provide higher inclusion-to-background contrast. In summary, our initial results were consistent with our expectations and what have been reported in the literature. The proposed (open-source) simulation platform can serve as a single gateway to perform many elastographic simulations in a transparent manner, thereby promoting collaborative developments.

Rocket study of auroral processes

NASA Technical Reports Server (NTRS)

Arnoldy, R. L.

1981-01-01

Abstracts are presented of previously published reports analyzing data from three Echo 3 rocket flights. Particle experiments designed for the Terrier-Malmute flight, the Echo 5 flight, and the Norwegian Corbier Ferdinand 50 flight are described and their flight performance evaluated. Theoretical studies on auroral particle precipitation are reviewed according to observations made in three regions of space: (1) the region accessible to rockets and low altitude satellites (few hundred to a few thousand kilometers); (2) the region extending from 4000 to 8000 km (S3-3 satellite range); and (3) near the equatorial plane (geosynchronous satellite measurements). Questions raised about auroral arc formation are considered.

Boundary scattering in the Φ$$^{4}$$ model

DOE PAGES

Dorey, Patrick; Halavanau, Aliaksei; Mercer, James; ...

2017-05-19

Here, we study boundary scattering in themore » $$\\phi^4$$ model on a half-line with a one-parameter family of Neumann-type boundary conditions. A rich variety of phenomena is observed, which extends previously-studied behaviour on the full line to include regimes of near-elastic scattering, the restoration of a missing scattering window, and the creation of a kink or oscillon through the collision-induced decay of a metastable boundary state. We also study the decay of the vibrational boundary mode, and explore different scenarios for its relaxation and for the creation of kinks.« less

Occurrence of Trypanosoma cruzi in Maryland

USGS Publications Warehouse

Herman, C.M.; Bruce, J.I.

1962-01-01

During 1954-1960, 2005 mammals of 18 species collected at the Patuxent Wildlife Research Center, Maryland, were examined for trypanosomes. T. cruzi was found in 10 raccoons between October 31 and November 30. Infection occurred in 2 percent of all raccoons sampled, and in 11.3 percent of the 80 raccoons sampled in November. Examination was by direct smears, stained smears and cultures of heart blood. Although, in previous studies, at least two experimentally infected raccoons exhibited extended parasitemia (14 and 8 weeks), no such continuing parasitemia was observed in the natural infections. No trypanosomes were found in any of the other mammals examined.

Diffuse X-ray emission from the Dumbbell Nebula?

NASA Technical Reports Server (NTRS)

Chu, You-Hua; Kwitter, Karen B.; Kaler, James B.

1993-01-01

We have analyzed ROSAT Position Sensitive Proportional Counter pointed observations of the Dumbbell Nebula and find that the previously reported 'extended' X-ray emission is an instrumental electronic ghost image at the softest energy band. At slightly higher energy bands, the image of the Dumbbell is not very different from that of the white dwarf HZ43. We conclude that the X-ray emission of the Dumbbell Nebula comes from its central star. A blackbody model is fitted to the spectrum and the best-fit temperature of not greater than 136,000 +/- 10,000 K is in excellent agreement with the Zanstra temperatures.

Influence of the extraocular muscle proprioceptors on the orientation of the vestibulo-ocular reflex.

PubMed

Pettorossi, V E; Errico, P; Ferraresi, A; Manni, E

1996-03-01

In the intact brain lamb, unilateral electrolytic lesion of the medial dorso-lateral portion of the semilunar ganglion containing the first order neurons of the eye muscle proprioception induced modifications of the horizontal and vertical vestibulo-ocular reflex (HVOR and VVOR) which consisted in marked alterations of the trajectories of the quick phases, while the slow phases were scarcely affected. Similar results were observed after section of the branches described by Winckler in the retrobulbar region along the extraocular muscle proprioceptive information travels. These findings extend those of previous investigations carried out in decorticate animals.

He 2-104 - A symbiotic proto-planetary nebula?

NASA Technical Reports Server (NTRS)

Schwarz, Hugo E.; Aspin, Colin; Lutz, Julie H.

1989-01-01

CCD observations are presented for He 2-104, an object previously classified as both PN and symbiotic star, which show that this is in fact a protoplanetary nebula (PPN) with a dynamical age of about 800 yr. The presence of highly collimated jets, extending over 75 arcsec on the sky, combined with an energy distribution showing a hot as well as a cool component, indicates that He 2-104 is a binary PPN. Since the primary is probably a Mira with a 400-d period (as reported by Whitelock, 1988), it is proposed that the system is a symbiotic PPN.

A Chandra High-Resolution X-ray Image of Centaurus A.

PubMed

Kraft; Forman; Jones; Kenter; Murray; Aldcroft; Elvis; Evans; Fabbiano; Isobe; Jerius; Karovska; Kim; Prestwich; Primini; Schwartz; Schreier; Vikhlinin

2000-03-01

We present first results from a Chandra X-Ray Observatory observation of the radio galaxy Centaurus A with the High-Resolution Camera. All previously reported major sources of X-ray emission including the bright nucleus, the jet, individual point sources, and diffuse emission are resolved or detected. The spatial resolution of this observation is better than 1&arcsec; in the center of the field of view and allows us to resolve X-ray features of this galaxy not previously seen. In particular, we resolve individual knots of emission in the inner jet and diffuse emission between the knots. All of the knots are diffuse at the 1&arcsec; level, and several exhibit complex spatial structure. We find the nucleus to be extended by a few tenths of an arcsecond. Our image also suggests the presence of an X-ray counterjet. Weak X-ray emission from the southwest radio lobe is also seen, and we detect 63 pointlike galactic sources (probably X-ray binaries and supernova remnants) above a luminosity limit of approximately 1.7x1037 ergs s-1.

The 700-1500 cm{sup −1} region of the S{sub 1} (A{sup ~1}B{sub 2}) state of toluene studied with resonance-enhanced multiphoton ionization (REMPI), zero-kinetic-energy (ZEKE) spectroscopy, and time-resolved slow-electron velocity-map imaging (tr-SEVI) spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gardner, Adrian M.; Green, Alistair M.; Tamé-Reyes, Victor M.

We report (nanosecond) resonance-enhanced multiphoton ionization (REMPI), (nanosecond) zero-kinetic-energy (ZEKE) and (picosecond) time-resolved slow-electron velocity map imaging (tr-SEVI) spectra of fully hydrogenated toluene (Tol-h{sub 8}) and the deuterated-methyl group isotopologue (α{sub 3}-Tol-d{sub 3}). Vibrational assignments are made making use of the activity observed in the ZEKE and tr-SEVI spectra, together with the results from quantum chemical and previous experimental results. Here, we examine the 700–1500 cm{sup −1} region of the REMPI spectrum, extending our previous work on the region ≤700 cm{sup −1}. We provide assignments for the majority of the S{sub 1} and cation bands observed, and in particular wemore » gain insight regarding a number of regions where vibrations are coupled via Fermi resonance. We also gain insight into intramolecular vibrational redistribution in this molecule.« less

Water transport, free volume, and polymer dynamics in crosslinked polymer networks

NASA Astrophysics Data System (ADS)

Frieberg, Bradley; Soles, Christopher

Many technologies rely on amorphous polymer membranes that selectively transport small molecules or ions, which has led to a significant scientific interest in elucidating the mechanisms of transport. A recurring theme among several different materials systems is that free volume and polymer chain dynamics facilitate transport. In order to understand the interplay between free volume, transport and polymer dynamics we quantify these properties for a model epoxy network. The epoxy chemistry allows for systematically varying both the structural rigidity of the network as well as the cross-link density. We performed positron annihilation lifetime spectroscopy measurements to characterize the unoccupied volume and correlated the unoccupied volume to the equilibrium moisture uptake and effective diffusion coefficient. We have recently extended this work to include polymer dynamics measured by quasi-elastic neutron scattering on the NIST High Flux Backscatter Spectrometer. These measurements reveal a strong correlation between the MSD and the transport kinetics, which was even stronger than the correlation previously observed between free volume and water diffusion. These observations challenge previous theories that suggest free volume governs transport.

The jet/wind outflow in Centaurus A: a local laboratory for AGN feedback

NASA Astrophysics Data System (ADS)

McKinley, B.; Tingay, S. J.; Carretti, E.; Ellis, S.; Bland-Hawthorn, J.; Morganti, R.; Line, J.; McDonald, M.; Veilleux, S.; Wahl Olsen, R.; Sidonio, M.; Ekers, R.; Offringa, A. R.; Procopio, P.; Pindor, B.; Wayth, R. B.; Hurley-Walker, N.; Bernardi, G.; Gaensler, B. M.; Haverkorn, M.; Kesteven, M.; Poppi, S.; Staveley-Smith, L.

2018-03-01

We present new radio and optical images of the nearest radio galaxy Centaurus A and its host galaxy NGC 5128. We focus our investigation on the northern transition region, where energy is transported from the ˜5 kpc (˜5 arcmin) scales of the northern inner lobe (NIL) to the ˜30 kpc (˜30 arcmin) scales of the northern middle lobe (NML). Our Murchison Widefield Array observations at 154 MHz and our Parkes radio telescope observations at 2.3 GHz show diffuse radio emission connecting the NIL to the NML, in agreement with previous Australia Telescope Compact Array observations at 1.4 GHz. Comparison of these radio data with our wide-field optical emission-line images show the relationship between the NML radio emission and the ionized filaments that extend north from the NIL, and reveal a new ionized filament to the east, possibly associated with a galactic wind. Our deep optical images show clear evidence for a bipolar outflow from the central galaxy extending to intermediate scales, despite the non-detection of a southern radio counterpart to the NML. Thus, our observational overview of Centaurus A reveals a number of features proposed to be associated with active galactic nucleus feedback mechanisms, often cited as likely to have significant effects in galaxy evolution models. As one of the closest galaxies to us, Centaurus A therefore provides a unique laboratory to examine feedback mechanisms in detail.

Matter bounce cosmology with a generalized single field: non-Gaussianity and an extended no-go theorem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yu-Bin; Cai, Yi-Fu; Quintin, Jerome

We extend the matter bounce scenario to a more general theory in which the background dynamics and cosmological perturbations are generated by a k -essence scalar field with an arbitrary sound speed. When the sound speed is small, the curvature perturbation is enhanced, and the tensor-to-scalar ratio, which is excessively large in the original model, can be sufficiently suppressed to be consistent with observational bounds. Then, we study the primordial three-point correlation function generated during the matter-dominated contraction stage and find that it only depends on the sound speed parameter. Similar to the canonical case, the shape of the bispectrummore » is mainly dominated by a local form, though for some specific sound speed values a new shape emerges and the scaling behaviour changes. Meanwhile, a small sound speed also results in a large amplitude of non-Gaussianities, which is disfavored by current observations. As a result, it does not seem possible to suppress the tensor-to-scalar ratio without amplifying the production of non-Gaussianities beyond current observational constraints (and vice versa). This suggests an extension of the previously conjectured no-go theorem in single field nonsingular matter bounce cosmologies, which rules out a large class of models. However, the non-Gaussianity results remain as a distinguishable signature of matter bounce cosmology and have the potential to be detected by observations in the near future.« less

Deep Chandra observations of HCG 16. II. The development of the intra-group medium in a spiral-rich group

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Sullivan, E.; Vrtilek, J. M.; David, L. P.

2014-10-01

We use a combination of deep Chandra X-ray observations and radio continuum imaging to investigate the origin and current state of the intra-group medium (IGM) in the spiral-rich compact group HCG 16. We confirm the presence of a faint (L {sub X,} {sub bolo} = 1.87{sub −0.66}{sup +1.03}×10{sup 41} erg s{sup –1}), low-temperature (0.30{sub −0.05}{sup +0.07} keV) IGM extending throughout the ACIS-S3 field of view, with a ridge linking the four original group members and extending to the southeast, as suggested by previous ROSAT and XMM-Newton observations. This ridge contains 6.6{sub −3.3}{sup +3.9}× 10{sup 9} M {sub ☉} of hotmore » gas and is at least partly coincident with a large-scale H I tidal filament, indicating that the IGM in the inner part of the group is highly multi-phase. We present evidence that the group is not yet virialized, and show that gas has probably been transported from the starburst winds of NGC 838 and NGC 839 into the surrounding IGM. Considering the possible origin of the IGM, we argue that material ejected by galactic winds may have played a significant role, contributing 20%-40% of the observed hot gas in the system.« less

RXTE and BeppoSAX Observations of the Transient X-ray Pulsar XTE J 18591+083

NASA Technical Reports Server (NTRS)

Corbet, R. H. D.; intZand, J. J. M.; Levine, A. M.; Marshall, F. E.

2008-01-01

We present observations of the 9.8 s X-ray pulsar XTE J159+083 made with the All-Sky Monitor (ASM) and Proportional Counter Array (PCA) on board the Rossi X-ray Timing Explorer (RXTE), and the Wide Field Cameras (WFC) on board BeppoSAX. The ASM data cover a 12 year time interval and show that an extended outburst occurred between approximately MJD50, 250, and 50, 460 (1996 June 16 to 1997 January 12). The ASM data excluding this outburst interval suggest a possible 61 day modulation. Eighteen sets of PCA observations were obtained over an approx. one month interval in 1999. The flux variability measured with the PCA appears consistent with the possible period found with the ASM. The PCA measurements of the pulse period showed it to decrease non-monotonically and then to increase significantly. Doppler shifts due to orbital motion rather than accretion torques appear to be better able to explain the pulse period changes. Observations with the WFC during the extended outburst give an error box which is consistent with a previously determined PCA error box but is significantly smaller. The transient nature of XTE J1859+083 and the length of its pulse period are consistent with it being a Be/neutral star binary. The possible 61 day orbital period would be of the expected length for a Be star system with a 9.8 s pulse period.

The role of Chandra in ten years from now and for the next few decades of astrophysical research

NASA Astrophysics Data System (ADS)

D'Abrusco, Raffaele; Becker, Glenn E.; McCollough, Michael L.; Rots, Arnold H.; Thong, Sinh A.; Van Stone, David; Winkelman, Sherry

2018-06-01

For almost twenty years, Chandra has advanced our understanding of the X-ray Universe by allowing astronomers to peer into a previously unexplored region of the high-energy observational parameters space. Thanks to its longevity,the mission has accumulated a large, unique body of observations whose legacy value, already tangible at this point, will only increase with time, and whose long-lasting influence extends well beyond the energy interval probed by Chandra. The Chandra archive, through the extensive characterization of the links between observations and literature, has measured the impact of Chandra on the astrophysical literature at a high level of granularity, providing striking evidence of how deeply and widely Chandra has impacted the advancement of both high-energy astrophysics and astronomical research from a multi-wavelength perspective. In this talk, based on the missions that have been submitted for recommendation at the next decadal survey and the possible outcomes of the evaluation process, I will discuss how Chandra archival data can be used to anticipate the projected scientific success and long-lasting effects of a X-ray mission like Lynx or, differently, how they will become instrumental to maximize the scientific output of a new generation of facilities that will observe in different energies. I will argue that, in either scenario, the centrality of Chandra will extend well after the final demise of the mission, and its data will continue serving the community in many different ways for the foreseeable future.

Imaging systems level consolidation of novel associate memories: A longitudinal neuroimaging study

PubMed Central

Smith, Jason F; Alexander, Gene E; Chen, Kewei; Husain, Fatima T; Kim, Jieun; Pajor, Nathan; Horwitz, Barry

2010-01-01

Previously, a standard theory of systems level memory consolidation was developed to describe how memory recall becomes independent of the medial temporal memory system. More recently, an extended consolidation theory was proposed that predicts seven changes in regional neural activity and inter-regional functional connectivity. Using longitudinal event related functional magnetic resonance imaging of an associate memory task, we simultaneously tested all predictions and additionally tested for consolidation related changes in recall of associate memories at a sub-trial temporal resolution, analyzing cue, delay and target periods of each trial separately. Results consistent with the theoretical predictions were observed though two inconsistent results were also obtained. In particular, while recall-related delay period activity decreased with consolidation as predicted, visual cue activity increased for consolidated memories. Though the extended theory of memory consolidation is largely supported by our study, these results suggest the extended theory needs further refinement and the medial temporal memory system has multiple, temporally distinct roles in associate memory recall. Neuroimaging analysis at a sub-trial temporal resolution, as used here, may further clarify the role of the hippocampal complex in memory consolidation. PMID:19948227

Branchial placenta in the viviparous teleost Ilyodon whitei (Goodeidae).

PubMed

Uribe, Mari Carmen; De la Rosa-Cruz, Gabino; García-Alarcón, Adriana

2014-12-01

Intraluminal gestation, as it occurs in viviparous goodeids, allows a wide diversity of embryo-maternal metabolic exchanges. The branchial placenta occurs in embryos developing in intraluminal gestation when ovarian folds enter through the operculum, into the branchial chamber. The maternal ovarian folds may extend to the embryonic pharyngeal cavity. A branchial placenta has been observed in few viviparous teleosts, and there are not previous histological analyses. This study analysis the histological structure in the goodeid Ilyodon whitei. The moterno ovarian folds extend through the embryonic operculum and reach near the gills, occupying part of the branchial chamber. These folds extend also into the pharyngeal cavity. In some regions, the epithelia of the ovarian folds and embryo were in apposition, developing a placental structure in which, maternal and embryonic capillaries lie in close proximity. The maternal epithelium has desquamated cells which may enter through the branchial chamber to the pharyngeal cavity and the alimentary tract. The complex processes that occur in the ovaries of viviparous teleosts, and its diverse adaptations for viviparity, as the presence of branchial placenta, are relevant in the study of the evolution of vertebrate viviparity. © 2014 Wiley Periodicals, Inc.

The ionization efficiency of aluminum and iron at meteoric velocities

NASA Astrophysics Data System (ADS)

DeLuca, Michael; Munsat, Tobin; Thomas, Evan; Sternovsky, Zoltan

2018-07-01

The ionization efficiency of aluminum was measured in the laboratory over an extended velocity range of 10.8-73.4 km/s and compared to available models. The measurements were made by shooting submicron-sized aluminum dust particles into an air chamber using the University of Colorado's dust accelerator facility. The ionization efficiency, β, is calculated from the total charge generated in the chamber during the complete ablation of particles of known mass. An array of photomultiplier tubes observed the light production by a subset of particles in the chamber to confirm that a moderate deceleration of the ablating particles occurred at low velocities. This information allows the interpretation of the β measurements to be extended to velocities <20 km/s, with the understanding that the low-velocity β measurements are lower limits. Updated β measurements for iron particles are also reported over an extended velocity range compared to previously published data: 10.5-87.3 km/s. The measurements are fit to functions for the ionization efficiency across the entire velocity range, and a semi-empirical function is presented which matches the shape of the measured β curves for aluminum and iron at both high and low velocities.

Impaired inference in a case of developmental amnesia.

PubMed

D'Angelo, Maria C; Rosenbaum, R Shayna; Ryan, Jennifer D

2016-10-01

Amnesia is associated with impairments in relational memory, which is critically supported by the hippocampus. By adapting the transitivity paradigm, we previously showed that age-related impairments in inference were mitigated when judgments could be predicated on known pairwise relations, however, such advantages were not observed in the adult-onset amnesic case D.A. Here, we replicate and extend this finding in a developmental amnesic case (N.C.), who also shows impaired relational learning and transitive expression. Unlike D.A., N.C.'s damage affected the extended hippocampal system and diencephalic structures, and does not extend to neocortical areas that are affected in D.A. Critically, despite their differences in etiology and affected structures, N.C. and D.A. perform similarly on the task. N.C. showed intact pairwise knowledge, suggesting that he is able to use existing semantic information, but this semantic knowledge was insufficient to support transitive expression. The present results suggest a critical role for regions connected to the hippocampus and/or medial prefrontal cortex in inference beyond learning of pairwise relations. © 2016 The Authors Hippocampus Published by Wiley Periodicals, Inc. © 2016 The Authors. Wiley Periodicals, Inc.

The Einstein database of IPC x-ray observations of optically selected and radio-selected quasars, 1.

NASA Technical Reports Server (NTRS)

Wilkes, Belinda J.; Tananbaum, Harvey; Worrall, D. M.; Avni, Yoram; Oey, M. S.; Flanagan, Joan

1994-01-01

We present the first volume of the Einstein quasar database. The database includes estimates of the X-ray count rates, fluxes, and luminosities for 514 quasars and Seyfert 1 galaxies observed with the Imaging Proportional Counter (IPC) aboard the Einstein Observatory. All were previously known optically selected or radio-selected objects, and most were the targets of the X-ray observations. The X-ray properties of the Active Galactic Nuclei (AGNs) have been derived by reanalyzing the IPC data in a systematic manner to provide a uniform database for general use by the astronomical community. We use the database to extend earlier quasar luminosity studies which were made using only a subset of the currently available data. The database can be accessed on internet via the SAO Einstein on-line system ('Einline') and is available in ASCII format on magnetic tape and DOS diskette.

High-spin lifetime measurements in the N=Z nucleus Kr72

NASA Astrophysics Data System (ADS)

Andreoiu, C.; Svensson, C. E.; Afanasjev, A. V.; Austin, R. A. E.; Carpenter, M. P.; Dashdorj, D.; Finlay, P.; Freeman, S. J.; Garrett, P. E.; Greene, J.; Grinyer, G. F.; Görgen, A.; Hyland, B.; Jenkins, D.; Johnston-Theasby, F.; Joshi, P.; Machiavelli, A. O.; Moore, F.; Mukherjee, G.; Phillips, A. A.; Reviol, W.; Sarantites, D. G.; Schumaker, M. A.; Seweryniak, D.; Smith, M. B.; Valiente-Dobón, J. J.; Wadsworth, R.

2007-04-01

High-spin states in the N=Z nucleus Kr72 have been populated in the Ca40(Ca40, 2α)Kr72 fusion-evaporation reaction at a beam energy of 165 MeV using the Gammasphere array for γ-ray detection coupled to the Microball array for charged particle detection. The previously observed bands in Kr72 were extended to an excitation energy of ˜24 MeV and angular momentum of 30ℏ. Using the Doppler shift attenuation method the lifetimes of high-spin states were measured for the first time. Excellent agreement between the results of calculations within the isovector mean field theory and experiment is observed both for rotational and deformation properties. No enhancement of quadrupole deformation expected in the presence of isoscalar t=0 np pairing is observed. Current data do not show any evidence for the existence of the isoscalar np pairing.

Fast internal dynamics in alcohol dehydrogenase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Monkenbusch, M.; Stadler, A., E-mail: a.stadler@fz-juelich.de; Biehl, R.

2015-08-21

Large-scale domain motions in alcohol dehydrogenase (ADH) have been observed previously by neutron spin-echo spectroscopy (NSE). We have extended the investigation on the dynamics of ADH in solution by using high-resolution neutron time-of-flight (TOF) and neutron backscattering (BS) spectroscopy in the incoherent scattering range. The observed hydrogen dynamics were interpreted in terms of three mobility classes, which allowed a simultaneous description of the measured TOF and BS spectra. In addition to the slow global protein diffusion and domain motions observed by NSE, a fast internal process could be identified. Around one third of the protons in ADH participate in themore » fast localized diffusive motion. The diffusion coefficient of the fast internal motions is around two third of the value of the surrounding D{sub 2}O solvent. It is tempting to associate the fast internal process with solvent exposed amino acid residues with dangling side chains.« less

NGC 2024: Far-infrared and radio molecular observations

NASA Technical Reports Server (NTRS)

Thronson, H. A., Jr.; Lada, C. J.; Schwartz, P. R.; Smith, H. A.; Smith, J.; Glaccum, W.; Harper, D. A.; Loewenstein, R. F.

1984-01-01

Far infrared continuum and millimeter wave molecular observations are presented for the infrared and radio source NGC 2024. The measurements are obtained at relatively high angular resolution, enabling a description of the source energetics and mass distribution in greater detail than previously reported. The object appears to be dominated by a dense ridge of material, extended in the north/south direction and centered on the dark lane that is seen in visual photographs. Maps of the source using the high density molecules CS and HCN confirm this picture and allow a description of the core structure and molecular abundances. The radio molecular and infrared observations support the idea that an important exciting star in NGC 2024 has yet to be identified and is centered on the dense ridge about 1' south of the bright mid infrared source IRS 2. The data presented here allows a presentation of a model for the source.

Electronic structure and optical properties of CdSxSe1-x solid solution nanostructures from X-ray absorption near edge structure, X-ray excited optical luminescence, and density functional theory investigations

NASA Astrophysics Data System (ADS)

Murphy, M. W.; Yiu, Y. M.; Ward, M. J.; Liu, L.; Hu, Y.; Zapien, J. A.; Liu, Yingkai; Sham, T. K.

2014-11-01

The electronic structure and optical properties of a series of iso-electronic and iso-structural CdSxSe1-x solid solution nanostructures have been investigated using X-ray absorption near edge structure, extended X-ray absorption fine structure, and X-ray excited optical luminescence at various absorption edges of Cd, S, and Se. It is found that the system exhibits compositions, with variable local structure in-between that of CdS and CdSe accompanied by tunable optical band gap between that of CdS and CdSe. Theoretical calculation using density functional theory has been carried out to elucidate the observations. It is also found that luminescence induced by X-ray excitation shows new optical channels not observed previously with laser excitation. The implications of these observations are discussed.

Determining fundamental properties of matter created in ultrarelativistic heavy-ion collisions

NASA Astrophysics Data System (ADS)

Novak, J.; Novak, K.; Pratt, S.; Vredevoogd, J.; Coleman-Smith, C. E.; Wolpert, R. L.

2014-03-01

Posterior distributions for physical parameters describing relativistic heavy-ion collisions, such as the viscosity of the quark-gluon plasma, are extracted through a comparison of hydrodynamic-based transport models to experimental results from 100AGeV+100AGeV Au +Au collisions at the Relativistic Heavy Ion Collider. By simultaneously varying six parameters and by evaluating several classes of observables, we are able to explore the complex intertwined dependencies of observables on model parameters. The methods provide a full multidimensional posterior distribution for the model output, including a range of acceptable values for each parameter, and reveal correlations between them. The breadth of observables and the number of parameters considered here go beyond previous studies in this field. The statistical tools, which are based upon Gaussian process emulators, are tested in detail and should be extendable to larger data sets and a higher number of parameters.

Hi-C and AIA observations of transverse magnetohydrodynamic waves in active regions

NASA Astrophysics Data System (ADS)

Morton, R. J.; McLaughlin, J. A.

2013-05-01

The recent launch of the High resolution Coronal imager (Hi-C) provided a unique opportunity of studying the EUV corona with unprecedented spatial resolution. We utilize these observations to investigate the properties of low-frequency (50-200 s) active region transverse waves, whose omnipresence had been suggested previously. The five-fold improvement in spatial resolution over SDO/AIA reveals coronal loops with widths 150-310 km and that these loops support transverse waves with displacement amplitudes <50 km. However, the results suggest that wave activity in the coronal loops is of low energy, with typical velocity amplitudes <3 km s-1. An extended time-series of SDO data suggests that low-energy wave behaviour is typical of the coronal structures both before and after the Hi-C observations. Appendix A and five movies associated to Figs. A.2-A.6 are available in electronic form at http://www.aanda.org

Afterslip, tremor, and the Denali fault earthquake

USGS Publications Warehouse

Gomberg, Joan; Prejean, Stephanie; Ruppert, Natalia

2012-01-01

We tested the hypothesis that afterslip should be accompanied by tremor using observations of seismic and aseismic deformation surrounding the 2002 M 7.9 Denali fault, Alaska, earthquake (DFE). Afterslip happens more frequently than spontaneous slow slip and has been observed in a wider range of tectonic environments, and thus the existence or absence of tremor accompanying afterslip may provide new clues about tremor generation. We also searched for precursory tremor, as a proxy for posited accelerating slip leading to rupture. Our search yielded no tremor during the five days prior to the DFE or in several intervals in the three months after. This negative result and an array of other observations all may be explained by rupture penetrating below the presumed locked zone into the frictional transition zone. While not unique, such an explanation corroborates previous models of megathrust and transform earthquake ruptures that extend well into the transition zone.

Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice.

PubMed

Soulard, Valérie; Bosson-Vanga, Henriette; Lorthiois, Audrey; Roucher, Clémentine; Franetich, Jean-François; Zanghi, Gigliola; Bordessoulles, Mallaury; Tefit, Maurel; Thellier, Marc; Morosan, Serban; Le Naour, Gilles; Capron, Frédérique; Suemizu, Hiroshi; Snounou, Georges; Moreno-Sabater, Alicia; Mazier, Dominique

2015-07-24

Experimental studies of Plasmodium parasites that infect humans are restricted by their host specificity. Humanized mice offer a means to overcome this and further provide the opportunity to observe the parasites in vivo. Here we improve on previous protocols to achieve efficient double engraftment of TK-NOG mice by human primary hepatocytes and red blood cells. Thus, we obtain the complete hepatic development of P. falciparum, the transition to the erythrocytic stages, their subsequent multiplication, and the appearance of mature gametocytes over an extended period of observation. Furthermore, using sporozoites derived from two P. ovale-infected patients, we show that human hepatocytes engrafted in TK-NOG mice sustain maturation of the liver stages, and the presence of late-developing schizonts indicate the eventual activation of quiescent parasites. Thus, TK-NOG mice are highly suited for in vivo observations on the Plasmodium species of humans.

Systematic Observation of an Expert Driver's Gaze Strategy—An On-Road Case Study

PubMed Central

Lappi, Otto; Rinkkala, Paavo; Pekkanen, Jami

2017-01-01

In this paper we present and qualitatively analyze an expert driver's gaze behavior in natural driving on a real road, with no specific experimental task or instruction. Previous eye tracking research on naturalistic tasks has revealed recurring patterns of gaze behavior that are surprisingly regular and repeatable. Lappi (2016) identified in the literature seven “qualitative laws of gaze behavior in the wild”: recurring patterns that tend to go together, the more so the more naturalistic the setting, all of them expected in extended sequences of fully naturalistic behavior. However, no study to date has observed all in a single experiment. Here, we wanted to do just that: present observations supporting all the “laws” in a single behavioral sequence by a single subject. We discuss the laws in terms of unresolved issues in driver modeling and open challenges for experimental and theoretical development. PMID:28496422

Relative importance of different surface regions for thermal comfort in humans.

PubMed

Nakamura, Mayumi; Yoda, Tamae; Crawshaw, Larry I; Kasuga, Momoko; Uchida, Yuki; Tokizawa, Ken; Nagashima, Kei; Kanosue, Kazuyuki

2013-01-01

In a previous study, we investigated the contribution of the surface of the face, chest, abdomen, and thigh to thermal comfort by applying local temperature stimulation during whole-body exposure to mild heat or cold. In hot conditions, humans prefer a cool face, and in cold they prefer a warm abdomen. In this study, we extended investigation of regional differences in thermal comfort to the neck, hand, soles, abdomen (Experiment 1), the upper and lower back, upper arm, and abdomen (Experiment 2). The methodology was similar to that used in the previous study. To compare the results of each experiment, we utilized the abdomen as the reference area in these experiments. Thermal comfort feelings were not particularly strong for the limbs and extremities, in spite of the fact that changes in skin temperature induced by local temperature stimulation of the limbs and extremities were always larger than changes that were induced in the more proximal body parts. For the trunk areas, a significant difference in thermal comfort was not observed among the abdomen, and upper and lower back. An exception involved local cooling during whole-body mild cold exposure, wherein the most dominant preference was for a warmer temperature of the abdomen. As for the neck and abdomen, clear differences were observed during local cooling, while no significant difference was observed during local warming. We combined the results for the current and the previous study, and characterized regional differences in thermal comfort and thermal preference for the whole-body surface.

Simulating the universe(s) III: observables for the full bubble collision spacetime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Matthew C.; Perimeter Institute for Theoretical Physics, Waterloo, Ontario N2L 2Y5; Wainwright, Carroll L.

2016-07-14

This is the third paper in a series establishing a quantitative relation between inflationary scalar field potential landscapes and the relic perturbations left by the collision between bubbles produced during eternal inflation. We introduce a new method for computing cosmological observables from numerical relativity simulations of bubble collisions in one space and one time dimension. This method tiles comoving hypersurfaces with locally-perturbed Friedmann-Robertson-Walker coordinate patches. The method extends previous work, which was limited to the spacetime region just inside the future light cone of the collision, and allows us to explore the full bubble-collision spacetime. We validate our new methodsmore » against previous work, and present a full set of predictions for the comoving curvature perturbation and local negative spatial curvature produced by identical and non-identical bubble collisions, in single scalar field models of eternal inflation. In both collision types, there is a non-zero contribution to the spatial curvature and cosmic microwave background quadrupole. Some collisions between non-identical bubbles excite wall modes, giving extra structure to the predicted temperature anisotropies. We comment on the implications of our results for future observational searches. For non-identical bubble collisions, we also find that the surfaces of constant field can readjust in the presence of a collision to produce spatially infinite sections that become nearly homogeneous deep into the region affected by the collision. Contrary to previous assumptions, this is true even in the bubble into which the domain wall is accelerating.« less

Simulating the universe(s) III: observables for the full bubble collision spacetime

NASA Astrophysics Data System (ADS)

Johnson, Matthew C.; Wainwright, Carroll L.; Aguirre, Anthony; Peiris, Hiranya V.

2016-07-01

This is the third paper in a series establishing a quantitative relation between inflationary scalar field potential landscapes and the relic perturbations left by the collision between bubbles produced during eternal inflation. We introduce a new method for computing cosmological observables from numerical relativity simulations of bubble collisions in one space and one time dimension. This method tiles comoving hypersurfaces with locally-perturbed Friedmann-Robertson-Walker coordinate patches. The method extends previous work, which was limited to the spacetime region just inside the future light cone of the collision, and allows us to explore the full bubble-collision spacetime. We validate our new methods against previous work, and present a full set of predictions for the comoving curvature perturbation and local negative spatial curvature produced by identical and non-identical bubble collisions, in single scalar field models of eternal inflation. In both collision types, there is a non-zero contribution to the spatial curvature and cosmic microwave background quadrupole. Some collisions between non-identical bubbles excite wall modes, giving extra structure to the predicted temperature anisotropies. We comment on the implications of our results for future observational searches. For non-identical bubble collisions, we also find that the surfaces of constant field can readjust in the presence of a collision to produce spatially infinite sections that become nearly homogeneous deep into the region affected by the collision. Contrary to previous assumptions, this is true even in the bubble into which the domain wall is accelerating.

Another Simple yet Effective Best Practice for Increasing Enrollments at an Extended Campus

ERIC Educational Resources Information Center

Christensen, Steven S.; Howell, Scott L.; Hall, C. Giles

2016-01-01

This article is a follow-up to a previous article, "Six Ways to Increase Enrollments at an Extended Campus," published in this journal (vol. 17, no. 4, winter 2015), wherein a seventh best practice to increase course offerings and increase enrollments at an extended campus is presented. This best practice seeks to identify those areas of…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cabello, Adan

We introduce an extended version of a previous all-versus-nothing proof of impossibility of Einstein-Podolsky-Rosen's local elements of reality for two photons entangled both in polarization and path degrees of freedom (A. Cabello, quant-ph/0507259), which leads to a Bell's inequality where the classical bound is 8 and the quantum prediction is 16. A simple estimation of the detection efficiency required to close the detection loophole using this extended version gives {eta}>0.69. This efficiency is lower than that required for previous proposals.

Transformation of nonlinear discrete-time system into the extended observer form

NASA Astrophysics Data System (ADS)

Kaparin, V.; Kotta, Ü.

2018-04-01

The paper addresses the problem of transforming discrete-time single-input single-output nonlinear state equations into the extended observer form, which, besides the input and output, also depends on a finite number of their past values. Necessary and sufficient conditions for the existence of both the extended coordinate and output transformations, solving the problem, are formulated in terms of differential one-forms, associated with the input-output equation, corresponding to the state equations. An algorithm for transformation of state equations into the extended observer form is proposed and illustrated by an example. Moreover, the considered approach is compared with the method of dynamic observer error linearisation, which likewise is intended to enlarge the class of systems transformable into an observer form.

Revised and extended analysis of the eighth spectrum of platinum (Pt VIII)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azarov, Vladimir I., E-mail: vlad_azarov@yahoo.com; Gayasov, Robert R.

2017-05-15

The spectrum of platinum was observed in the 300–2100 Å wavelength region. Grazing and normal incidence VUV spectrographs have been used to record the spectrum. The (5d{sup 3}+5d{sup 2}6s)−5d{sup 2}6p transition array of seven times ionized platinum, Pt VIII, has been investigated. The configurations 5d{sup 3} and 5d{sup 2}6p had been previously studied, and all levels of these configurations (19 and 45 levels, respectively) had been established. The previous analysis was based on 178 classified spectral lines. In the current analysis we have confirmed identification of all previously found levels and all but 10 previously assigned spectral lines, although we havemore » detected a large (up to 35 mÅ) systematic shift in wavelength measurements used in the previous analysis. Based on new wavelength measurements, we have corrected the 5d{sup 3} and 5d{sup 2}6p energy level values (by up to 55 cm{sup −1}) and established for the first time 14 out of 16 theoretically possible 5d{sup 2}6s levels in Pt VIII. The total list of identified lines (including 180 new lines) contains 349 entries. The orthogonal operators technique was used to calculate the level structure and transition probabilities. The energy parameters have been determined by the least squares fit to the observed levels. Calculated transition probability and energy values, as well as LS-compositions obtained from the fitted parameters are presented.« less

AKARI OBSERVATION OF THE SUB-DEGREE SCALE FLUCTUATION OF THE NEAR-INFRARED BACKGROUND

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seo, H. J.; Lee, Hyung Mok; Lee, Myung Gyoon

2015-07-10

We report spatial fluctuation analysis of the sky brightness in the near-infrared from observations toward the north ecliptic pole (NEP) by the AKARI at 2.4 and 3.2 μm. As a follow-up study of our previous work on the Monitor field of AKARI, we used NEP deep survey data, which covered a circular area of about 0.4 square degrees, in order to extend fluctuation analysis at angular scales up to 1000″. We found residual fluctuation over the estimated shot noise at larger angles than the angular scale of the Monitor field. The excess fluctuation of the NEP deep field smoothly connectsmore » with that of the Monitor field at angular scales of a few hundred arcseconds and extends without any significant variation to larger angular scales up to 1000″. By comparing excess fluctuations at two wavelengths, we confirm a blue spectral feature similar to the result of the Monitor field. We find that the result of this study is consistent with Spitzer Space Telescope observations at 3.6 μm. The origin of the excess fluctuation in the near-infrared background remains to be determined, but we could exclude zodiacal light, diffuse Galactic light, and unresolved faint galaxies at low redshift based on the comparison with mid- and far-infrared brightness, ground-based near-infrared images.« less

Local properties of magnetic reconnection in nonlinear resistive- and extended-magnetohydrodynamic toroidal simulations of the sawtooth crash

DOE PAGES

Beidler, M. T.; Cassak, P. A.; Jardin, S. C.; ...

2016-12-15

We diagnose local properties of magnetic reconnection during a sawtooth crash employing the three-dimensional toroidal, extended-magnetohydrodynamic (MHD) code M3D-C 1. To do so, we sample simulation data in the plane in which reconnection occurs, the plane perpendicular to the helical (m, n) = (1, 1) mode at the q = 1 surface, where m and n are the poloidal and toroidal mode numbers and q is the safety factor. We study the nonlinear evolution of a particular test equilibrium in a non-reduced field representation using both resistive-MHD and extended-MHD models. We find growth rates for the extended-MHD reconnection process exhibitmore » a nonlinear acceleration and greatly exceed that of the resistive-MHD model, as is expected from previous experimental, theoretical, and computational work. We compare the properties of reconnection in the two simulations, revealing the reconnecting current sheets are locally different in the two models and we present the first observation of the quadrupole out-of-plane Hall magnetic field that appears during extended-MHD reconnection in a 3D toroidal simulation (but not in resistive-MHD). We also explore the dependence on toroidal angle of the properties of reconnection as viewed in the plane perpendicular to the helical magnetic field, finding qualitative and quantitative effects due to changes in the symmetry of the reconnection process. Furthermore, this study is potentially important for a wide range of magnetically confined fusion applications, from confirming simulations with extended-MHD effects are sufficiently resolved to describe reconnection, to quantifying local reconnection rates for purposes of understanding and predicting transport, not only at the q = 1 rational surface for sawteeth, but also at higher order rational surfaces that play a role in disruptions and edge-confinement degradation.« less

Mapping the information landscape: Discerning peaks and valleys for ecological monitoring

USGS Publications Warehouse

Moniz, L.J.; Nichols, J.D.; Nichols, J.M.

2007-01-01

We investigate previously unreported phenomena that have a potentially significant impact on the design of surveillance monitoring programs for ecological systems. Ecological monitoring practitioners have long recognized that different species are differentially informative of a system?s dynamics, as codified in the well-known concepts of indicator or keystone species. Using a novel combination of analysis techniques from nonlinear dynamics, we describe marked variation among spatial sites in information content with respect to system dynamics in the entire region. We first observed these phenomena in a spatially extended predator?prey model, but we observed strikingly similar features in verified water-level data from a NOAA/NOS Great Lakes monitoring program. We suggest that these features may be widespread and the design of surveillance monitoring programs should reflect knowledge of their existence.

Simple neural substrate predicts complex rhythmic structure in duetting birds

NASA Astrophysics Data System (ADS)

Amador, Ana; Trevisan, M. A.; Mindlin, G. B.

2005-09-01

Horneros (Furnarius Rufus) are South American birds well known for their oven-looking nests and their ability to sing in couples. Previous work has analyzed the rhythmic organization of the duets, unveiling a mathematical structure behind the songs. In this work we analyze in detail an extended database of duets. The rhythms of the songs are compatible with the dynamics presented by a wide class of dynamical systems: forced excitable systems. Compatible with this nonlinear rule, we build a biologically inspired model for how the neural and the anatomical elements may interact to produce the observed rhythmic patterns. This model allows us to synthesize songs presenting the acoustic and rhythmic features observed in real songs. We also make testable predictions in order to support our hypothesis.

Methodology for turbulence code validation: Quantification of simulation-experiment agreement and application to the TORPEX experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ricci, Paolo; Theiler, C.; Fasoli, A.

A methodology for plasma turbulence code validation is discussed, focusing on quantitative assessment of the agreement between experiments and simulations. The present work extends the analysis carried out in a previous paper [P. Ricci et al., Phys. Plasmas 16, 055703 (2009)] where the validation observables were introduced. Here, it is discussed how to quantify the agreement between experiments and simulations with respect to each observable, how to define a metric to evaluate this agreement globally, and - finally - how to assess the quality of a validation procedure. The methodology is then applied to the simulation of the basic plasmamore » physics experiment TORPEX [A. Fasoli et al., Phys. Plasmas 13, 055902 (2006)], considering both two-dimensional and three-dimensional simulation models.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aad, G.

Results are reported of a search for new phenomena, such as supersymmetric particle production, that could be observed in high-energy proton–proton collisions. Events with large numbers of jets, together with missing transverse momentum from unobserved particles, are selected. The data analysed were recorded by the ATLAS experiment during 2015 using the 13 TeV centre-of-mass proton–proton collisions at the Large Hadron Collider, and correspond to an integrated luminosity of 3.2 fb -1. The search selected events with various jet multiplicities from ≥7 to ≥10 jets, and with various b-jet multiplicity requirements to enhance sensitivity. Furthermore, no excess above Standard Model expectationsmore » is observed. The results are interpreted within two supersymmetry models, where gluino masses up to 1400 GeV are excluded at 95% confidence level, significantly extending previous limits.« less

Evidence for high-energy extraterrestrial neutrinos at the IceCube detector.

PubMed

Aartsen, M G; Abbasi, R; Abdou, Y; Ackermann, M; Adams, J; Aguilar, J A; Ahlers, M; Altmann, D; Auffenberg, J; Bai, X; Baker, M; Barwick, S W; Baum, V; Bay, R; Beatty, J J; Bechet, S; Becker Tjus, J; Becker, K-H; Benabderrahmane, M L; BenZvi, S; Berghaus, P; Berley, D; Bernardini, E; Bernhard, A; Bertrand, D; Besson, D Z; Binder, G; Bindig, D; Bissok, M; Blaufuss, E; Blumenthal, J; Boersma, D J; Bohaichuk, S; Bohm, C; Bose, D; Böser, S; Botner, O; Brayeur, L; Bretz, H-P; Brown, A M; Bruijn, R; Brunner, J; Carson, M; Casey, J; Casier, M; Chirkin, D; Christov, A; Christy, B; Clark, K; Clevermann, F; Coenders, S; Cohen, S; Cowen, D F; Cruz Silva, A H; Danninger, M; Daughhetee, J; Davis, J C; Day, M; De Clercq, C; De Ridder, S; Desiati, P; de Vries, K D; de With, M; DeYoung, T; Díaz-Vélez, J C; Dunkman, M; Eagan, R; Eberhardt, B; Eichmann, B; Eisch, J; Ellsworth, R W; Euler, S; Evenson, P A; Fadiran, O; Fazely, A R; Fedynitch, A; Feintzeig, J; Feusels, T; Filimonov, K; Finley, C; Fischer-Wasels, T; Flis, S; Franckowiak, A; Frantzen, K; Fuchs, T; Gaisser, T K; Gallagher, J; Gerhardt, L; Gladstone, L; Glüsenkamp, T; Goldschmidt, A; Golup, G; Gonzalez, J G; Goodman, J A; Góra, D; Grandmont, D T; Grant, D; Groß, A; Ha, C; Haj Ismail, A; Hallen, P; Hallgren, A; Halzen, F; Hanson, K; Heereman, D; Heinen, D; Helbing, K; Hellauer, R; Hickford, S; Hill, G C; Hoffman, K D; Hoffmann, R; Homeier, A; Hoshina, K; Huelsnitz, W; Hulth, P O; Hultqvist, K; Hussain, S; Ishihara, A; Jacobi, E; Jacobsen, J; Jagielski, K; Japaridze, G S; Jero, K; Jlelati, O; Kaminsky, B; Kappes, A; Karg, T; Karle, A; Kelley, J L; Kiryluk, J; Kläs, J; Klein, S R; Köhne, J-H; Kohnen, G; Kolanoski, H; Köpke, L; Kopper, C; Kopper, S; Koskinen, D J; Kowalski, M; Krasberg, M; Krings, K; Kroll, G; Kunnen, J; Kurahashi, N; Kuwabara, T; Labare, M; Landsman, H; Larson, M J; Lesiak-Bzdak, M; Leuermann, M; Leute, J; Lünemann, J; Madsen, J; Maggi, G; Maruyama, R; Mase, K; Matis, H S; McNally, F; Meagher, K; Merck, M; Meures, T; Miarecki, S; Middell, E; Milke, N; Miller, J; Mohrmann, L; Montaruli, T; Morse, R; Nahnhauer, R; Naumann, U; Niederhausen, H; Nowicki, S C; Nygren, D R; Obertacke, A; Odrowski, S; Olivas, A; O'Murchadha, A; Paul, L; Pepper, J A; Pérez de los Heros, C; Pfendner, C; Pieloth, D; Pinat, E; Posselt, J; Price, P B; Przybylski, G T; Rädel, L; Rameez, M; Rawlins, K; Redl, P; Reimann, R; Resconi, E; Rhode, W; Ribordy, M; Richman, M; Riedel, B; Rodrigues, J P; Rott, C; Ruhe, T; Ruzybayev, B; Ryckbosch, D; Saba, S M; Salameh, T; Sander, H-G; Santander, M; Sarkar, S; Schatto, K; Scheriau, F; Schmidt, T; Schmitz, M; Schoenen, S; Schöneberg, S; Schönwald, A; Schukraft, A; Schulte, L; Schulz, O; Seckel, D; Sestayo, Y; Seunarine, S; Shanidze, R; Sheremata, C; Smith, M W E; Soldin, D; Spiczak, G M; Spiering, C; Stamatikos, M; Stanev, T; Stasik, A; Stezelberger, T; Stokstad, R G; Stößl, A; Strahler, E A; Ström, R; Sullivan, G W; Taavola, H; Taboada, I; Tamburro, A; Tepe, A; Ter-Antonyan, S; Tešić, G; Tilav, S; Toale, P A; Toscano, S; Unger, E; Usner, M; van Eijndhoven, N; Van Overloop, A; van Santen, J; Vehring, M; Voge, M; Vraeghe, M; Walck, C; Waldenmaier, T; Wallraff, M; Weaver, Ch; Wellons, M; Wendt, C; Westerhoff, S; Whitehorn, N; Wiebe, K; Wiebusch, C H; Williams, D R; Wissing, H; Wolf, M; Wood, T R; Woschnagg, K; Xu, D L; Xu, X W; Yanez, J P; Yodh, G; Yoshida, S; Zarzhitsky, P; Ziemann, J; Zierke, S; Zoll, M

2013-11-22

We report on results of an all-sky search for high-energy neutrino events interacting within the IceCube neutrino detector conducted between May 2010 and May 2012. The search follows up on the previous detection of two PeV neutrino events, with improved sensitivity and extended energy coverage down to about 30 TeV. Twenty-six additional events were observed, substantially more than expected from atmospheric backgrounds. Combined, both searches reject a purely atmospheric origin for the 28 events at the 4σ level. These 28 events, which include the highest energy neutrinos ever observed, have flavors, directions, and energies inconsistent with those expected from the atmospheric muon and neutrino backgrounds. These properties are, however, consistent with generic predictions for an additional component of extraterrestrial origin.

The Extended Mind: Coupling Environment and Brain

NASA Astrophysics Data System (ADS)

Vrobel, Susie

2010-11-01

This paper describes embodiment and cognitive extension as examples of strong anticipation as defined by Dubois. Clark and Chalmers formulated a thesis which states that parts of the environment, if coupled successfully, can become part of the extended mind. This coupling, be it deliberate or unintentional, shifts the observer-world boundary outwards when the observer encompasses parts of his environment. The resulting extended observer forms a new systemic whole, which consists of both the assimilated context and the recalibrated version of the original observer. Recalibration occurs when conditioning and adaptation lead to corresponding changes on the neural level, for instance, when an agent compensates for delays in a control loop. Plasticity is a prerequisite for any successful incorporation of external structures. However, uncoupled parts of the observer must remain inviolate in order to preserve the boundary. Neither the extended mind nor the core observer are absolute concepts. Depending on whether we focus on local-scale interactions or on large-scale behaviour, boundaries are formed at different interfacial cuts, which lead to either an endo- or an exo-perspective or endo- or exo-anticipation, respectively. For biological extended agents which undergo a transition from exo- to endo-states, a tell-tale sign of a successful exo-endo transition is invisibility. This invisibility occurs when the agent is no longer aware of the delay originally introduced into the control loop by the assimilated part of the environment. Explaining the world in terms of effective causality is not sufficient to account for extended minds. The latter require explanations in terms of final causation. For extended minds, this ordering principle comes in the shape of nested hierarchical layers. The interfaces of these layers may have merged for an endo-observer, whereas an exo-observer can make out the detailed structure, including artificially introduced delays. A sufficient condition for an endo-observer to turn into an extended mind is the formation of a new systemic whole as a result of shifting the interfacial cut between exo-and endo-world outwards. However, this is only a necessary condition for an extended agent with strong anticipatory properties. It is invisibility which is a sufficient condition for strong or endo-anticipation.

On the azimuthal size of flux ropes near lunar orbit

NASA Astrophysics Data System (ADS)

Kiehas, S. A.; Angelopoulos, V.; Runov, A.; Li, S.-S.

2013-07-01

We present Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun (ARTEMIS) dual-probe observations of flux ropes in the Earth's magnetotail near lunar orbit. On 15 July 2011 between 0400 and 0500 UT, the ARTEMIS probes (P1 and P2) are separated by ˜ (9/10/3) RE(XGSW/YGSW/ZGSW). GSW denotes the Geocentric Solar Wind coordinate system and differs from the GSM coordinate system in that its X axis is antiparallel to the solar wind. P1 is near midnight and P2 in the postmidnight sector at ˜ -13 RE YGSW. During a ˜ 50 min interval on 15 July 2011, P1 crossed the current sheet and encountered a flux rope thereafter. During the same interval, P2 observed only one flux rope near the time P1 crossed the current sheet but no flux rope or traveling compression region (TCR) for P1's subsequent flux rope observation. A Tsyganenko-Fairfield model and minimum variance analysis during the current sheet crossing are used to infer the current sheet location with respect to the probes. We find the distance between P2 and the plasma sheet boundary to be less than 3 RE. Under these circumstances, P2 would be expected to observe a TCR if the flux rope observed by P1 extended to the postmidnight location of P2. The lack of such observations indicates that, contrary to previous models and simulation results, flux ropes may be spatially confined in the dusk-dawn direction and do not extend across the entire cross section of the tail near lunar orbit.

Ceramic-based microelectrode arrays: recording surface characteristics and topographical analysis

PubMed Central

Talauliker, Pooja M.; Price, David A.; Burmeister, Jason J.; Nagari, Silpa; Quintero, Jorge E.; Pomerleau, Francois; Huettl, Peter; Hastings, J. Todd; Gerhardt, Greg A.

2011-01-01

Amperometric measurements using microelectrode arrays (MEAs) provide spatially and temporally resolved measures of neuromolecules in the central nervous system of rats, mice and non-human primates. Multi-site MEAs can be mass fabricated on ceramic (Al2O3) substrate using photolithographic methods, imparting a high level of precision and reproducibility in a rigid but durable recording device. Although the functional capabilities of MEAs have been previously documented for both anesthetized and freely-moving paradigms, the performance enabling intrinsic physical properties of the MEA device have not heretofore been presented. In these studies, spectral analysis confirmed that the MEA recording sites were primarily composed of elemental platinum (Pt°). In keeping with the precision of the photolithographic process, scanning electron microscopy revealed that the Pt recording sites have unique microwell geometries post-fabrication. Atomic force microscopy demonstrated that the recording surfaces have nanoscale irregularities in the form of elevations and depressions, which contribute to increased current per unit area that exceeds previously reported microelectrode designs. The ceramic substrate on the back face of the MEA was characterized by low nanoscale texture and the ceramic sides consisted of an extended network of ridges and cavities. Thus, individual recording sites have a unique Pt° composition and surface profile that has not been previously observed for Pt-based microelectrodes. These features likely impact the physical chemistry of the device, which may influence adhesion of biological molecules and tissue as well as electrochemical recording performance post-implantation. This study is a necessary step towards understanding and extending the performance abilities of MEAs in vivo. PMID:21513736

Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle

PubMed Central

Montanari, Arianna; De Luca, Cristina; Di Micco, Patrizio; Morea, Veronica; Frontali, Laura; Francisci, Silvia

2011-01-01

Previous work has demonstrated the usefulness of the yeast model to investigate the molecular mechanisms underlying defects due to base substitutions in mitochondrial tRNA genes, and to identify suppressing molecules endowed with potential clinical relevance. The present paper extends these investigations to two human equivalent yeast mutations located at positions 32 and 33 in the anticodon loop of tRNAIle. Notwithstanding the proximity of the two T>C base substitutions, the effects of these mutations have been found to be quite different in yeast, as they are in human. The T32C substitution has a very severe effect in yeast, consisting in a complete inhibition of growth on nonfermentable substrates. Conversely, respiratory defects caused by the T33C mutation could only be observed in a defined genetic context. Analyses of available sequences and selected tRNA three-dimensional structures were performed to provide explanations for the different behavior of these adjacent mutations. Examination of the effects of previously identified suppressors demonstrated that overexpression of the TUF1 gene did not rescue the defective phenotypes determined by either mutation, possibly as a consequence of the lack of interactions between EF-Tu and the tRNA anticodon arm in known structures. On the contrary, both the cognate IleRS and the noncognate LeuRS and ValRS are endowed with suppressing activities toward both mutations. This allows us to extend to the tRNAIle mutants the cross-suppression activity of aminoacyl-tRNA synthetases previously demonstrated for tRNALeu and tRNAVal mutants. PMID:21914842

Probing the extent of the non-thermal emission from the Vela X region at TeV energies with H.E.S.S.

NASA Astrophysics Data System (ADS)

Abramowski, A.; Acero, F.; Aharonian, F.; Akhperjanian, A. G.; Anton, G.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker Tjus, J.; Bernlöhr, K.; Birsin, E.; Biteau, J.; Bochow, A.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Carrigan, S.; Casanova, S.; Cerruti, M.; Chadwick, P. M.; Charbonnier, A.; Chaves, R. C. G.; Cheesebrough, A.; Cologna, G.; Conrad, J.; Couturier, C.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; deWilt, P.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; Drury, L. O.' C.; Dubois, F.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Egberts, K.; Eger, P.; Espigat, P.; Fallon, L.; Farnier, C.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fernandez, D.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Gast, H.; Giebels, B.; Glicenstein, J. F.; Glück, B.; Göring, D.; Grondin, M.-H.; Häffner, S.; Hague, J. D.; Hahn, J.; Hampf, D.; Harris, J.; Heinz, S.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Komin, Nu.; Kosack, K.; Kossakowski, R.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lenain, J.-P.; Lennarz, D.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Masbou, J.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Medina, M. C.; Méhault, J.; Menzler, U.; Moderski, R.; Mohamed, M.; Moulin, E.; Naumann, C. L.; Naumann-Godo, M.; de Naurois, M.; Nedbal, D.; Nguyen, N.; Niemiec, J.; Nolan, S. J.; Ohm, S.; de Oña Wilhelmi, E.; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Parsons, D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raue, M.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Ripken, J.; Rob, L.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sheidaei, F.; Skilton, J. L.; Sol, H.; Spengler, G.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Szostek, A.; Tavernet, J.-P.; Terrier, R.; Tluczykont, M.; Trichard, C.; Valerius, K.; van Eldik, C.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorobiov, S.; Vorster, M.; Wagner, S. J.; Ward, M.; White, R.; Wierzcholska, A.; Wouters, D.; Zacharias, M.; Zajczyk, A.; Zdziarski, A. A.; Zech, A.; Zechlin, H.-S.

2012-12-01

Context. Vela X is a region of extended radio emission in the western part of the Vela constellation: one of the nearest pulsar wind nebulae, and associated with the energetic Vela pulsar (PSR B0833-45). Extended very-high-energy (VHE) γ-ray emission (HESS J0835-455) was discovered using the H.E.S.S. experiment in 2004. The VHE γ-ray emission was found to be coincident with a region of X-ray emission discovered with ROSAT above 1.5 keV (the so-called Vela X cocoon): a filamentary structure extending southwest from the pulsar to the centre of Vela X. Aims: A deeper observation of the entire Vela X nebula region, also including larger offsets from the cocoon, has been performed with H.E.S.S. This re-observation was carried out in order to probe the extent of the non-thermal emission from the Vela X region at TeV energies and to investigate its spectral properties. Methods: To increase the sensitivity to the faint γ-ray emission from the very extended Vela X region, a multivariate analysis method combining three complementary reconstruction techniques of Cherenkov-shower images is applied for the selection of γ-ray events. The analysis is performed with the On/Off background method, which estimates the background from separate observations pointing away from Vela X; towards regions free of γ-ray sources but with comparable observation conditions. Results: The γ-ray surface brightness over the large Vela X region reveals that the detection of non-thermal VHE γ-ray emission from the PWN HESS J0835-455 is statistically significant over a region of radius 1.2° around the position α = 08h35m00s, δ = -45°36'00'' (J2000). The Vela X region exhibits almost uniform γ-ray spectra over its full extent: the differential energy spectrum can be described by a power-law function with a hard spectral index Γ = 1.32 ± 0.06stat ± 0.12sys and an exponential cutoff at an energy of (14.0 ± 1.6stat ± 2.6sys) TeV. Compared to the previous H.E.S.S. observations of Vela X the new analysis confirms the general spatial overlap of the bulk of the VHE γ-ray emission with the X-ray cocoon, while its extent and morphology appear more consistent with the (more extended) radio emission, contradicting the simple correspondence between VHE γ-ray and X-ray emissions. Morphological and spectral results challenge the interpretation of the origin of γ-ray emission in the GeV and TeV ranges in the framework of current models.

The Molecular Envelope around the Red Supergiant VY CMa

NASA Astrophysics Data System (ADS)

Muller, S.; Dinh-V-Trung; Lim, J.; Hirano, N.; Muthu, C.; Kwok, S.

2007-02-01

We present millimeter interferometric observations of the molecular envelope around the red supergiant VY CMa with the Submillimeter Array (SMA). The high angular resolution (<2") allows us to derive the structure of the envelope as observed in the 1.3 mm continuum, 12CO(2-1), 13CO(2-1), and SO(65-54) lines emission. The circumstellar envelope is resolved into three components: (1) a dense, compact, and dusty central component, embedded in (2) a more diffuse and extended envelope, and (3) a high-velocity component. We construct a simple model, consisting of a spherically symmetric slowly expanding envelope and bipolar outflows with a wide opening angle (~120°) viewed close to the line of sight (i=15deg). Our model can explain the main features of the SMA data and previous single-dish CO multiline observations. An episode of enhanced mass loss along the bipolar direction is inferred from our modeling. The SMA data provide a better understanding of the complicated morphology seen in the optical/IR high-resolution observations.

Galaxy interactions in the Hickson Compact Group 88

NASA Astrophysics Data System (ADS)

Brosch, Noah

2015-12-01

I present observations of the Hickson Compact Group 88 (HCG88) obtained during the commissioning of a new 28-inch telescope at the Wise Observatory. This galaxy group was advertized to be non-interacting, or to be in a very early interaction stage, but this is not the case. The observations reported here were done using a `luminance' filter, essentially a very broad R filter, reaching a low surface brightness level of ≈26 mag arcsec-2. Additional observations were obtained in a narrow spectral band approximately centred on the rest-frame H α line from the group. Contrary to previous studies, my observations show that at least two of the major galaxies have had significant interactions in the past, although probably not between themselves. I report the discovery of a faint extended tail emerging from the brightest of the group galaxies, severe isophote twisting and possible outer shells around another galaxy, and map the H II regions in all the galaxies.

Campaign datasets for Two-Column Aerosol Project (TCAP)

DOE Data Explorer

Berg,Larry; Mei,Fan; Cairns,Brian; Chand,Duli; Comstock,Jennifer; Cziczo,Daniel; Hostetler,Chris; Hubbe,John; Long,Chuck; Michalsky,Joseph; Pekour,Mikhail; Russell,Phil; Scott,Herman; Sedlacek,Arthur; Shilling,John; Springston,Stephen; Tomlinson,Jason; Watson,Thomas; Zelenyuk-Imre,Alla

2013-12-30

This campaign was designed to provide a detailed set of observations with which to 1) perform radiative and cloud condensation nuclei (CCN) closure studies, 2) evaluate a new retrieval algorithm for aerosol optical depth (AOD) in the presence of clouds using passive remote sensing 3) extend a previously developed technique to investigate aerosol indirect effects, and 4) evaluate the performance of a detailed regional-scale model and a more parameterized global-scale model in simulating particle activation and AOD associated with the aging of anthropogenic aerosols. To meet these science objectives, the ARM Mobile Facility (AMF) and the Mobile Aerosol Observing System (MAOS) was deployed on Cape Cod, Massachusetts for a 12-month period starting in the summer of 2012 in order to quantify aerosol properties, radiation and cloud characteristics at a location subject to both clear- and cloudy- conditions, and clean- and polluted-conditions. These observations were supplemented by two aircraft intensive observation periods (IOPS), one in the summer and a second in the winter. Each IOP required two aircraft.

First Detection of a Pulsar Bow Shock Nebula in Far-UV: PSR J0437-4715

NASA Astrophysics Data System (ADS)

Rangelov, Blagoy; Pavlov, George G.; Kargaltsev, Oleg; Durant, Martin; Bykov, Andrei M.; Krassilchtchikov, Alexandre

2016-11-01

Pulsars traveling at supersonic speeds are often accompanied by cometary bow shocks seen in Hα. We report on the first detection of a pulsar bow shock in the far-ultraviolet (FUV). We detected it in FUV images of the nearest millisecond pulsar J0437-4715 obtained with the Hubble Space Telescope. The images reveal a bow-like structure positionally coincident with part of the previously detected Hα bow shock, with an apex at 10″ ahead of the moving pulsar. Its FUV luminosity, L(1250{--}2000 \\mathringA )≈ 5 × {10}28 erg s-1, exceeds the Hα luminosity from the same area by a factor of 10. The FUV emission could be produced by the shocked interstellar medium matter or, less likely, by relativistic pulsar wind electrons confined by strong magnetic field fluctuations in the bow shock. In addition, in the FUV images we found a puzzling extended (≃3″ in size) structure overlapping with the limb of the bow shock. If related to the bow shock, it could be produced by an inhomogeneity in the ambient medium or an instability in the bow shock. We also report on a previously undetected X-ray emission extending for about 5″ ahead of the pulsar, possibly a pulsar wind nebula created by shocked pulsar wind, with a luminosity L(0.5-8 keV) ˜ 3 × 1028 erg s-1. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. These observations are associated with programs GO 12917 and GO 10568.

Theory of mind as a link between oxytocin and maternal behavior.

PubMed

MacKinnon, Anna L; Carter, C Sue; Feeley, Nancy; Gold, Ian; Hayton, Barbara; Santhakumaran, Sangeetha; Zelkowitz, Phyllis

2018-06-01

Oxytocin is a neuropeptide associated with maternal behavior. However the mechanisms underlying this link remain unclear. In a previous study we observed an indirect effect of increased plasma oxytocin during late pregnancy on early postpartum maternal interactive behavior via theory of mind, as assessed by the Reading the Mind in the Eyes Test (RMET). The current study aimed to extend these findings by testing whether this indirect effect would hold longitudinally for maternal behavior at 2-3 years postpartum, as well as for an additional observational measure of maternal mind-mindedness. The original sample of 316 pregnant women (M age  = 31.92 years) was assessed at 12-14 weeks gestation (T1), 32-34 weeks gestation (T2), and 7-9 weeks postpartum (T3). Follow-up measures were taken at 2-3 years postpartum (T4). Mothers' RMET performance (T3) was associated with more structuring and less intrusive maternal behavior at 2-3 years (T4), while their tendency to use mind-related comments (T3) was associated with greater sensitivity (T4). Bootstrap estimates also revealed a significant indirect effect of plasma oxytocin levels during late pregnancy (T2) on maternal structuring and non-intrusive behavior at 2-3 years postpartum (T4) through RMET performance (T3). Results: of the current study confirm and extend the previous findings, demonstrating that theory of mind may represent a social cognitive mechanism linking endogenous oxytocin and maternal behavior. Important changes in the oxytocinergic system during late pregnancy may help prepare for motherhood by promoting the awareness of social cues, which in turn promote maternal behavior from the early postpartum to the early childhood years. Copyright © 2018 Elsevier Ltd. All rights reserved.

Solar Polar Jets Driven by Magnetic Reconnection, Gravity, and Wind

NASA Astrophysics Data System (ADS)

DeVore, C. Richard; Karpen, Judith T.; Antiochos, Spiro K.

2014-06-01

Polar jets are dynamic, narrow, radially extended structures observed in solar EUV emission near the limb. They originate within the open field of coronal holes in “anemone” regions, which are intrusions of opposite magnetic polarity. The key topological feature is a magnetic null point atop a dome-shaped fan surface of field lines. Applied stresses readily distort the null into a current patch, eventually inducing interchange reconnection between the closed and open fields inside and outside the fan surface (Antiochos 1996). Previously, we demonstrated that magnetic free energy stored on twisted closed field lines inside the fan surface is released explosively by the onset of fast reconnection across the current patch (Pariat et al. 2009, 2010). A dense jet comprised of a nonlinear, torsional Alfvén wave is ejected into the outer corona along the newly reconnected open field lines. Now we are extending those exploratory simulations by including the effects of solar gravity, solar wind, and expanding spherical geometry. We find that the model remains robust in the resulting more complex setting, with explosive energy release and dense jet formation occurring in the low corona due to the onset of a kink-like instability, as found in the earlier Cartesian, gravity-free, static-atmosphere cases. The spherical-geometry jet including gravity and wind propagates far more rapidly into the outer corona and inner heliosphere than a comparison jet simulation that excludes those effects. We report detailed analyses of our new results, compare them with previous work, and discuss the implications for understanding remote and in-situ observations of solar polar jets.This work was supported by NASA’s LWS TR&T program.

Effects of a free-choice high-fat high-sugar diet on brain PER2 and BMAL1 protein expression in mice.

PubMed

Blancas-Velazquez, Aurea; la Fleur, Susanne E; Mendoza, Jorge

2017-10-01

The suprachiasmatic nucleus (SCN) times the daily rhythms of behavioral processes including feeding. Beyond the SCN, the hypothalamic arcuate nucleus (ARC), involved in feeding regulation and metabolism, and the epithalamic lateral habenula (LHb), implicated in reward processing, show circadian rhythmic activity. These brain oscillators are functionally coupled to coordinate the daily rhythm of food intake. In rats, a free choice high-fat high-sugar (fcHFHS) diet leads to a rapid increase of calorie intake and body weight gain. Interestingly, under a fcHFHS condition, rats ingest a similar amount of sugar during day time (rest phase) as during night time (active phase), but keep the rhythmic intake of regular chow-food. The out of phase between feeding patterns of regular (chow) and highly rewarding food (sugar) may involve alterations of brain circadian oscillators regulating feeding. Here, we report that the fcHFHS diet is a successful model to induce calorie intake, body weight gain and fat tissue accumulation in mice, extending its effectiveness as previously reported in rats. Moreover, we observed that whereas in the SCN the day-night difference in the PER2 clock protein expression was similar between chow-fed and fcHFHS-fed animals, in the LHb, this day-night difference was altered in fcHFHS-exposed animals compared to control chow mice. These findings confirm previous observations in rats showing disrupted daily patterns of feeding behavior under a fcHFHS diet exposure, and extend our insights on the effects of the diet on circadian gene expression in brain clocks. Copyright © 2017 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bent, Clare L., E-mail: clare_bent@yahoo.co.uk; Low, Deborah; Matson, Matthew B.

The purpose of this study was to assess whether portal vein embolization (PVE) using a nitinol vascular plug in combination with histoacryl glue and iodinized oil minimizes the risk of nontarget embolization while obtaining good levels of future liver remnant (FLR) hypertrophy. Between November 2005 and August 2008, 16 patients (8 females, 8 males; mean age, 63 {+-} 3.6 years), each with a small FLR, underwent right ipsilateral transhepatic PVE prior to major hepatectomy. Proximal PVE was initially performed by placement of a nitinol vascular plug, followed by distal embolization using a mixture of histoacryl glue and iodinized oil. Pre-more » and 6 weeks postprocedural FLR volumes were calculated using computed tomographic imaging. Selection for surgery required an FLR of 0.5% of the patient's body mass. Clinical course and outcome of surgical resection for all patients were recorded. At surgery, the ease of hepatectomy was subjectively assessed in comparison to previous experience following PVE with alternative embolic agents. PVE was successful in all patients. Mean procedure time was 30.4 {+-} 2.5 min. Mean absolute increase in FLR volume was 68.9% {+-} 12.0% (p = 0.00005). There was no evidence of nontarget embolization during the procedure or on subsequent imaging. Nine patients proceeded to extended hepatectomy. Six patients demonstrated disease progression. One patient did not achieve sufficient hypertrophy in relation to body mass to undergo hepatic resection. At surgery, the hepatobiliary surgeons observed less periportal inflammation compared to previous experience with alternative embolic agents, facilitating dissection at extended hepatectomy. In conclusion, ipsilateral transhepatic PVE using a single nitinol plug in combination with histoacryl glue and iodinized oil simplifies the procedure, offering short procedural times with minimal risk of nontarget embolization. Excellent levels of FLR hypertrophy are achieved enabling safe extended hepatectomy.« less

Differential recruitment of brain networks in single-digit addition and multiplication: Evidence from EEG oscillations in theta and lower alpha bands.

PubMed

Wang, Lihan; Gan, John Q; Zhang, Li; Wang, Haixian

2018-06-01

Previous neuroimaging research investigating dissociation between single-digit addition and multiplication has suggested that the former placed more reliance on the visuo-spatial processing whereas the latter on the verbal processing. However, there has been little exploration into the disassociation in spatio-temporal dynamics of the oscillatory brain activity in specific frequency bands during the two arithmetic operations. To address this issue, the electroencephalogram (EEG) data were recorded from 19 participants engaged in a delayed verification arithmetic task. By analyzing oscillatory EEG activity in theta (5-7 Hz) and lower alpha frequency (9-10 Hz) bands, we found different patterns of oscillatory brain activity between single-digit addition and multiplication during the early processing stage (0-400 ms post-operand onset). Experiment results in this study showed a larger phasic increase of theta-band power for addition than for multiplication in the midline and the right frontal and central regions during the operator and operands presentation intervals, which was extended to the right parietal and the right occipito-temporal regions during the interval immediately after the operands presentation. In contrast, during multiplication higher phase-locking in lower alpha band was evident in the centro-parietal regions during the operator presentation, which was extended to the left fronto-central and anterior regions during the operands presentation. Besides, we found stronger theta phase synchrony between the parietal areas and the right occipital areas for single-digit addition than for multiplication during operands encoding. These findings of oscillatory brain activity extend the previous observations on functional dissociation between the two arithmetic operations. Copyright © 2018 Elsevier B.V. All rights reserved.

H I in group interactions: HCG 44

NASA Astrophysics Data System (ADS)

Hess, Kelley M.; Cluver, M. E.; Yahya, Sahba; Leisman, Lukas; Serra, Paolo; Lucero, Danielle M.; Passmoor, Sean S.; Carignan, Claude

2017-01-01

Extending deep observations of the neutral atomic hydrogen (H I) to the environment around galaxy groups can reveal a complex history of group interactions which is invisible to studies that focus on the stellar component. Hickson Compact Group 44 (HCG 44) is a nearby example, and we have combined H I data from the Karoo Array Telescope, Westerbork Synthesis Radio Telescope, and Arecibo Legacy Fast ALFA survey, in order to achieve high column density sensitivity (N _{H {I}}<2× 10^{18} cm-2) to the neutral gas over a large field of view beyond the compact group itself. We find that the giant H I tail north of HCG 44 contains 1.1 × 109 M⊙ of gas and extends 450 kpc from the compact group: twice as much mass and 33 per cent further than previously detected. However, the additional gas is still unable to account for the known H I deficiency of HCG 44. The tail likely formed through a strong tidal interaction and H I clouds in the tail have survived for 1 Gyr or more after being stripped. This has important implications for understanding the survival of neutral clouds in the intragroup and circumgroup medium, and we discuss their survival in the context of simulations of cold gas in hot haloes. HCG 44 is one of a growing number of galaxy groups found to have more extended H I in the intragroup and circumgroup medium than previously measured. Our results provide constraints for simulations on the properties of galaxy group haloes, and reveal a glimpse of what will be seen by future powerful H I telescopes and surveys.

Microflaring in Low-Lying Core Fields and Extended Coronal Heating in the Quiet Sun

NASA Technical Reports Server (NTRS)

Porter, Jason G.; Falconer, D. A.; Moore, Ronald L.

1999-01-01

We have previously reported analyses of Yohkoh SXT data examining the relationship between the heating of extended coronal loops (both within and stemming from active regions) and microflaring in core fields lying along neutral lines near their footpoints (J. G. Porter, D. A. Falconer, and R. L. Moore 1998, in Solar Jets and Coronal Plumes, ed. T. Guyenne, ESA SP-421, and references therein). We found a surprisingly poor correlation of intensity variations in the extended loops with individual microflares in the compact heated areas at their feet, despite considerable circumstancial evidence linking the heating processes in these regions. Now, a study of Fe XII image sequences from SOHO EIT show that similar associations of core field structures with the footpoints of very extended coronal features can be found in the quiet Sun. The morphology is consistent with the finding of Wang et al. (1997, ApJ 484, L75) that polar plumes are rooted at sites of mixed polarity in the magnetic network. We find that the upstairs/downstairs intensity variations often follow the trend, identified in the active region observations, of a weak correspondence. Apparently much of the coronal heating in the extended loops is driven by a type of core field magnetic activity that is "cooler" than the events having the coronal signature of microflares, i.e., activity that results in little heating within the core fields themselves. This work was funded by the Solar Physics Branch of NASA's Office of Space Science through the SR&T Program and the SEC Guest Investigator Program.

Micro RNAs from DNA Viruses are Found Widely in Plasma in a Large Observational Human Population.

PubMed

Koupenova, Milka; Mick, Eric; Corkrey, Heather A; Huan, Tianxiao; Clancy, Lauren; Shah, Ravi; Benjamin, Emelia J; Levy, Daniel; Kurt-Jones, Evelyn A; Tanriverdi, Kahraman; Freedman, Jane E

2018-04-23

Viral infections associate with disease risk and select families of viruses encode miRNAs that control an efficient viral cycle. The association of viral miRNA expression with disease in a large human population has not been previously explored. We sequenced plasma RNA from 40 participants of the Framingham Heart Study (FHS, Offspring Cohort, Visit 8) and identified 3 viral miRNAs from 3 different human Herpesviridae. These miRNAs were mostly related to viral latency and have not been previously detected in human plasma. Viral miRNA expression was then screened in the plasma of 2763 participants of the remaining cohort utilizing high-throughput RT-qPCR. All 3 viral miRNAs associated with combinations of inflammatory or prothrombotic circulating biomarkers (sTNFRII, IL-6, sICAM1, OPG, P-selectin) but did not associate with hypertension, coronary heart disease or cancer. Using a large observational population, we demonstrate that the presence of select viral miRNAs in the human circulation associate with inflammatory biomarkers and possibly immune response, but fail to associate with overt disease. This study greatly extends smaller singular observations of viral miRNAs in the human circulation and suggests that select viral miRNAs, such as those for latency, may not impact disease manifestation.

Near-Infrared Imaging Polarimetry of Inner Region of GG Tau A Disk

NASA Technical Reports Server (NTRS)

Yang, Yi; Hashimoto, Jun; Hayashi, Saeko S.; Tamura, Motohide; Mayama, Satoshi; Rafikov, Roman; Akiyama, Eiji; Carson, Joseph C.; Janson, Markus; Kwon, Jungmi;

Social perceptions versus meteorological observations of snow and winter along the Front Range

NASA Astrophysics Data System (ADS)

Milligan, William James, IV

This research aims to increase understanding of Front Range residents' perceptions of snow, winter and hydrologic events. This study also investigates how an individual's characteristics may shape perceptions of winter weather and climate. A survey was administered to determine if perceptions of previous winters align with observed meteorological data. The survey also investigated how individual characteristics influence perceptions of snow and winter weather. The survey was conducted primarily along the Front Range area of the state of Colorado in the United States of America. This is a highly populated semi-arid region that acts as an interface between the agricultural plains to the east that extend to the Mississippi River and the Rocky Mountains to the west. The climate is continental, and while many people recreate in the snowy areas of the mountains, most live where annual snowfall amounts are low. Precipitation, temperature, and wind speed datasets from selected weather stations were analyzed to determine correct survey responses. Survey analysis revealed that perceptions of previous winters do not necessarily align with observed meteorological data. The mean percentage of correct responses to all survey questions was 36.8%. Further analysis revealed that some individual characteristics (e.g. winter recreation, source of winter weather information) did influence correct responses to survey questions.

Spatial Distribution of Io's Neutral Oxygen Cloud Observed by Hisaki

NASA Astrophysics Data System (ADS)

Koga, Ryoichi; Tsuchiya, Fuminori; Kagitani, Masato; Sakanoi, Takeshi; Yoneda, Mizuki; Yoshioka, Kazuo; Yoshikawa, Ichiro; Kimura, Tomoki; Murakami, Go; Yamazaki, Atsushi; Smith, H. Todd; Bagenal, Fran

2018-05-01

We report on the spatial distribution of a neutral oxygen cloud surrounding Jupiter's moon Io and along Io's orbit observed by the Hisaki satellite. Atomic oxygen and sulfur in Io's atmosphere escape from the exosphere mainly through atmospheric sputtering. Some of the neutral atoms escape from Io's gravitational sphere and form neutral clouds around Jupiter. The extreme ultraviolet spectrograph called EXCEED (Extreme Ultraviolet Spectroscope for Exospheric Dynamics) installed on the Japan Aerospace Exploration Agency's Hisaki satellite observed the Io plasma torus continuously in 2014-2015, and we derived the spatial distribution of atomic oxygen emissions at 130.4 nm. The results show that Io's oxygen cloud is composed of two regions, namely, a dense region near Io and a diffuse region with a longitudinally homogeneous distribution along Io's orbit. The dense region mainly extends on the leading side of Io and inside of Io's orbit. The emissions spread out to 7.6 Jupiter radii (RJ). Based on Hisaki observations, we estimated the radial distribution of the atomic oxygen number density and oxygen ion source rate. The peak atomic oxygen number density is 80 cm-3, which is spread 1.2 RJ in the north-south direction. We found more oxygen atoms inside Io's orbit than a previous study. We estimated the total oxygen ion source rate to be 410 kg/s, which is consistent with the value derived from a previous study that used a physical chemistry model based on Hisaki observations of ultraviolet emission ions in the Io plasma torus.

Investigating the anticipatory nature of pattern perception in sport.

PubMed

Gorman, Adam D; Abernethy, Bruce; Farrow, Damian

2011-07-01

The aim of the present study was to examine the anticipatory nature of pattern perception in sport by using static and moving basketball patterns across three different display types. Participants of differing skill levels were included in order to determine whether the effects would be moderated by the knowledge and experience of the observer in the same manner reported previously for simple images. The results from a pattern recognition task showed that both expert and recreational participants were more likely to anticipate the next likely state of a pattern when it was presented as a moving video, but only the experts appeared to have the depth of understanding required to elicit the same anticipatory encoding for patterns presented as schematic images. The results extend those reported in previous research and provide further evidence of an anticipatory encoding in pattern perception for images containing complex, interrelated patterns.

Emotional body-word conflict evokes enhanced n450 and slow potential.

PubMed

Ma, Jianling; Liu, Chang; Zhong, Xin; Wang, Lu; Chen, Xu

2014-01-01

Emotional conflict refers to the influence of task irrelevant affective stimuli on current task set. Previously used emotional face-word tasks have produced certain electrophysiological phenomena, such as an enhanced N450 and slow potential; however, it remains unknown whether these effects emerge in other tasks. The present study used an emotional body-word conflict task to investigate the neural dynamics of emotional conflict as reflected by response time, accuracy, and event-related potentials, which were recorded with the aim of replicating the previously observed N450 and slow potential effect. Results indicated increased response time and decreased accuracy in the incongruent condition relative to the congruent condition, indicating a robust interference effect. Furthermore, the incongruent condition evoked pronounced N450 amplitudes and a more positive slow potential, which might be associated with conflict-monitoring and conflict resolution. The present findings extend our understanding of emotional conflict to the body-word domain.

Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways

PubMed Central

Moon, Yuseok; Kim, Jeung Il; Yang, Hyun; Eling, Thomas E.

2009-01-01

Previously, we reported that non-steroidal anti-inflammatory drugs (NSAIDs) suppress cellular invasion which was mediated by thrombospondin-1 (TSP-1). As the extending study of the previous observation, we investigated the effect of NSAID-induced TSP-1 on the cellular growth and its related signaling transduction of the TSP-1 production. Among diverse NSAIDs, sulindac sulfide was most potent of inducing the human TSP-1 protein expression. Functionally, induced TSP-1 expression was associated with the growth-compensatory action of NSAID. TSP-1 expression was also elevated by mitogenic signals of ERK1/2 and RhoA GTPase pathway which had also growth-promotive capability after sulindac sulfide treatment. These findings suggest the possible mechanism through which tumor cells can survive the chemopreventive action of NSAIDs or the normal epithelium can reconstitute after NSAID-mediated ulceration in a compensatory way. PMID:18261746

The Palliative Function of Hostile Sexism among High and Low-Status Chilean Students

PubMed Central

Vargas-Salfate, Salvador

2017-01-01

Previous studies have demonstrated that justifying the social, economic, and political systems is associated with psychological well-being, which has been termed as the palliative function of ideology. However, little research has been conducted on gender stereotypes among children, comparing by socioeconomic status. This study aimed to fill this gap in the system justification literature. We present data from the Chilean version of the International Survey of Children Well-Being (ISCWeB), which was conducted in 2012. We found that the palliative function of gender stereotypes is present among this sample, being qualified by a socioeconomic status by hostile gender stereotype interaction. In other words, the effect on the psychological well-being was observed in low-status, but not in high-status students. These results extend the previous knowledge about the palliative function of the ideology, suggesting why the low-status members of a society actively engage in system justification. PMID:29046657

Chemical Abundances of Planetary Nebulae in the Substructures of M31. II. The Extended Sample and a Comparison Study with the Outer-disk Group

NASA Astrophysics Data System (ADS)

Fang, Xuan; García-Benito, Rubén; Guerrero, Martín A.; Zhang, Yong; Liu, Xiaowei; Morisset, Christophe; Karakas, Amanda I.; Miller Bertolami, Marcelo M.; Yuan, Haibo; Cabrera-Lavers, Antonio

2018-01-01

We report deep spectroscopy of 10 planetary nebulae (PNe) in the Andromeda Galaxy (M31) using the 10.4 m Gran Telescopio Canarias (GTC). Our targets reside in different regions of M31, including halo streams and the dwarf satellite M32, and kinematically deviate from the extended disk. The temperature-sensitive [O III] λ4363 line is observed in all PNe. For four PNe, the GTC spectra extend beyond 1 μm, enabling the explicit detection of the [S III] λ6312 and λλ9069, 9531 lines and thus determination of the [S III] temperature. Abundance ratios are derived and generally consistent with AGB model predictions. Our PNe probably all evolved from low-mass (<2 M ⊙) stars, as analyzed with the most up-to-date post-AGB evolutionary models, and their main-sequence ages are mostly ∼2–5 Gyr. Compared to the underlying, smooth, metal-poor halo of M31, our targets are uniformly metal rich ([O/H] ≳ ‑0.4), and seem to resemble the younger population in the stream. We thus speculate that our halo PNe formed in the Giant Stream’s progenitor through extended star formation. Alternatively, they might have formed from the same metal-rich gas as did the outer-disk PNe but were displaced into their present locations as a result of galactic interactions. These interpretations are, although speculative, qualitatively in line with the current picture, as inferred from previous wide-field photometric surveys, that M31's halo is the result of complex interactions and merger processes. The behavior of the N/O of the combined sample of the outer-disk and our halo/substructure PNe signifies that hot bottom burning might actually occur at <3 M ⊙ but careful assessment is needed. Based on observations made with the Gran Telescopio Canarias, installed at the Spanish Observatorio del Roque de los Muchachos of Instituto de Astrofísica de Canarias, in the island of La Palma. The observations presented in this paper are associated with GTC programs #GTC66-16A and #GTC25-16B.

Cohort mortality study of garment industry workers exposed to formaldehyde: update and internal comparisons.

PubMed

Meyers, Alysha R; Pinkerton, Lynne E; Hein, Misty J

2013-09-01

To further evaluate the association between formaldehyde and leukemia, we extended follow-up through 2008 for a cohort mortality study of 11,043 US formaldehyde-exposed garment workers. We computed standardized mortality ratios and standardized rate ratios stratified by year of first exposure, exposure duration, and time since first exposure. Associations between exposure duration and rates of leukemia and myeloid leukemia were further examined using Poisson regression models. Compared to the US population, myeloid leukemia mortality was elevated but overall leukemia mortality was not. In internal analyses, overall leukemia mortality increased with increasing exposure duration and this trend was statistically significant. We continue to see limited evidence of an association between formaldehyde and leukemia. However, the extended follow-up did not strengthen previously observed associations. In addition to continued epidemiologic research, we recommend further research to evaluate the biological plausibility of a causal relation between formaldehyde and leukemia. Copyright © 2013 Wiley Periodicals, Inc.

The IRAS galaxy 0421+040P06: An active spiral (?) galaxy with extended radio lobes

NASA Technical Reports Server (NTRS)

Beichman, C. A.; Wynn-Williams, C. G.; Lonsdale, C. J.; Persson, S. E.; Heasley, J. N.; Miley, G. K.; Soifer, B. T.; Neugebauer, G.; Becklin, E. E.; Houck, J. R.

1984-01-01

The infrared bright galaxy 0421+040P06 detected by IRAS at 25 and 60 microns was studied at optical, infrared, and radio wavelength. It is a luminous galaxy with apparent spiral structure emitting 4 x 10 to the 37th power from far-infrared to optical wavelengths. Optical spectroscopy reveals a Seyfert 2 emission line spectrum, making 0421+040P06 the first active galaxy selected from an unbiased infrared survey of galaxies. The fact that this galaxy shows a flatter energy distribution with more 25 micron emission than other galaxies in the infrared sample may be related to the presence of an intense active nucleus. The radio observations reveal the presence of a non-thermal source that, at 6 cm, shows a prominent double lobed structure 20 to 30 kpc in size extending beyond the optical confines of the galaxy. The radio source is three to ten times larger than structures previously seen in spiral galaxies.

Mediation of donor–acceptor distance in an enzymatic methyl transfer reaction

PubMed Central

Zhang, Jianyu; Kulik, Heather J.; Martinez, Todd J.; Klinman, Judith P.

2015-01-01

Enzymatic methyl transfer, catalyzed by catechol-O-methyltransferase (COMT), is investigated using binding isotope effects (BIEs), time-resolved fluorescence lifetimes, Stokes shifts, and extended graphics processing unit (GPU)-based quantum mechanics/molecular mechanics (QM/MM) approaches. The WT enzyme is compared with mutants at Tyr68, a conserved residue that is located behind the reactive sulfur of cofactor. Small (>1) BIEs are observed for an S-adenosylmethionine (AdoMet)-binary and abortive ternary complex containing 8-hydroxyquinoline, and contrast with previously reported inverse (<1) kinetic isotope effects (KIEs). Extended GPU-based computational studies of a ternary complex containing catecholate show a clear trend in ground state structures, from noncanonical bond lengths for WT toward solution values with mutants. Structural and dynamical differences that are sensitive to Tyr68 have also been detected using time-resolved Stokes shift measurements and molecular dynamics. These experimental and computational results are discussed in the context of active site compaction that requires an ionization of substrate within the enzyme ternary complex. PMID:26080432

First experimental evidence of hydrodynamic tunneling of ultra-relativistic protons in extended solid copper target at the CERN HiRadMat facility

NASA Astrophysics Data System (ADS)

Schmidt, R.; Blanco Sancho, J.; Burkart, F.; Grenier, D.; Wollmann, D.; Tahir, N. A.; Shutov, A.; Piriz, A. R.

2014-08-01

A novel experiment has been performed at the CERN HiRadMat test facility to study the impact of the 440 GeV proton beam generated by the Super Proton Synchrotron on extended solid copper cylindrical targets. Substantial hydrodynamic tunneling of the protons in the target material has been observed that leads to significant lengthening of the projectile range, which confirms our previous theoretical predictions [N. A. Tahir et al., Phys. Rev. Spec. Top.-Accel. Beams 15, 051003 (2012)]. Simulation results show very good agreement with the experimental measurements. These results have very important implications on the machine protection design for powerful machines like the Large Hadron Collider (LHC), the future High Luminosity LHC, and the proposed huge 80 km circumference Future Circular Collider, which is currently being discussed at CERN. Another very interesting outcome of this work is that one may also study the field of High Energy Density Physics at this test facility.

Sunyaev-Zel'dovich Effect and X-ray Scaling Relations from Weak-Lensing Mass Calibration of 32 SPT Selected Galaxy Clusters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dietrich, J.P.; et al.

Uncertainty in the mass-observable scaling relations is currently the limiting factor for galaxy cluster based cosmology. Weak gravitational lensing can provide a direct mass calibration and reduce the mass uncertainty. We present new ground-based weak lensing observations of 19 South Pole Telescope (SPT) selected clusters and combine them with previously reported space-based observations of 13 galaxy clusters to constrain the cluster mass scaling relations with the Sunyaev-Zel'dovich effect (SZE), the cluster gas massmore » $$M_\\mathrm{gas}$$, and $$Y_\\mathrm{X}$$, the product of $$M_\\mathrm{gas}$$ and X-ray temperature. We extend a previously used framework for the analysis of scaling relations and cosmological constraints obtained from SPT-selected clusters to make use of weak lensing information. We introduce a new approach to estimate the effective average redshift distribution of background galaxies and quantify a number of systematic errors affecting the weak lensing modelling. These errors include a calibration of the bias incurred by fitting a Navarro-Frenk-White profile to the reduced shear using $N$-body simulations. We blind the analysis to avoid confirmation bias. We are able to limit the systematic uncertainties to 6.4% in cluster mass (68% confidence). Our constraints on the mass-X-ray observable scaling relations parameters are consistent with those obtained by earlier studies, and our constraints for the mass-SZE scaling relation are consistent with the the simulation-based prior used in the most recent SPT-SZ cosmology analysis. We can now replace the external mass calibration priors used in previous SPT-SZ cosmology studies with a direct, internal calibration obtained on the same clusters.« less

Exploring potential Pluto-generated neutral tori

NASA Astrophysics Data System (ADS)

Smith, Howard T.; Hill, Matthew; KollMann, Peter; McHutt, Ralph

2015-11-01

The NASA New Horizons mission to Pluto is providing unprecedented insight into this mysterious outer solar system body. Escaping molecular nitrogen is of particular interest and possibly analogous to similar features observed at moons of Saturn and Jupiter. Such escaping N2 has the potential of creating molecular nitrogen and N (as a result of molecular dissociation) tori or partial toroidal extended particle distributions. The presence of these features would present the first confirmation of an extended toroidal neutral feature on a planetary scale in our solar system. While escape velocities are anticipated to be lower than those at Enceladus, Io or even Europa, particle lifetimes are much longer in Pluto’s orbit because as a result of much weaker solar interaction processes along Pluto’s orbit (on the order of tens of years). Thus, with a ~248 year orbit, Pluto may in fact be generating an extended toroidal feature along it orbit.For this work, we modify and apply our 3-D Monte Carlo neutral torus model (previously used at Saturn, Jupiter and Mercury) to study/analyze the theoretical possibility and scope of potential Pluto-generated neutral tori. Our model injects weighted particles and tracks their trajectories under the influence of all gravitational fields with interactions with other particles, solar photons and Pluto collisions. We present anticipated N2 and N tori based on current estimates of source characterization and environmental conditions. We also present an analysis of sensitivity to assumed initial conditions. Such results can provide insight into the Pluto system as well as valuable interpretation of New Horizon’s observational data.

Green Tea Polyphenols Extend the Lifespan of Male Drosophila melanogaster While Impairing Reproductive Fitness

PubMed Central

Lopez, Terry; Schriner, Samuel E.; Okoro, Michael; Lu, David; Chiang, Beatrice T.; Huey, Jocelyn

2014-01-01

Abstract Green tea is a popular beverage believed to have many health benefits, including a reduction in the risks of heart disease and cancer. Rich in polyphenolic compounds known as catechins, green tea and its components have been shown to increase the lifespan of various animal models, including Drosophila melanogaster. Here, we investigated the gender-specific effects of green tea on the lifespan of fruit flies and observed that green tea extended the lifespan of male flies only. This effect was found to be independent of typical aging interventions, such as dietary restriction, modulation of oxidative energy metabolism, and improved tolerance to environmental stresses. The one exception was that green tea did protect male flies against iron toxicity. Since there is an inverse correlation between lifespan and reproduction, the impact of green tea on male reproductive fitness was also investigated. We found that green tea negatively impacted male fertility as shown by a reduced number of offspring produced and increased mating latency. We further identified that the lifespan extension properties of green tea was only observed in the presence of females which alludes to a reproductive (or mating) dependent mechanism. Our findings suggest that green tea extends the lifespan of male flies by inhibiting reproductive potential, possibly by limiting iron uptake. To our knowledge, our study is the first to report the negative impact of green tea on Drosophila male reproduction. Our results also support previous studies that suggest that green tea might have a negative effect on reproductive fitness in humans. PMID:25058464

The Changing Motivations of Students' Use of Lecture Podcasts across a Semester: An Extended Theory of Planned Behaviour Approach

ERIC Educational Resources Information Center

Moss, Nathan D.; Hamilton, Kyra; White, Katherine M.; Hansen, Julie

2015-01-01

We extended the previous work of Moss, O'Connor and White, to include a measure of group norms within the theory of planned behaviour (TPB), to examine the influences on students' decisions to use lecture podcasts as part of their learning. Participants (N?=?90) completed the extended TPB predictors before semester began (Time 1) and mid-semester…

ICU Acquisition Rate, Risk Factors, and Clinical Significance of Digestive Tract Colonization With Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae: A Systematic Review and Meta-Analysis.

PubMed

Detsis, Marios; Karanika, Styliani; Mylonakis, Eleftherios

2017-04-01

To evaluate the acquisition rate, identify risk factors, and estimate the risk for subsequent infection, associated with the colonization of the digestive tract with extended-spectrum beta-lactamase-producing Enterobacteriaceae during ICU-hospitalization. PubMed, EMBASE, and reference lists of all eligible articles. Included studies provided data on ICU-acquired colonization with extended-spectrum beta-lactamase-producing Enterobacteriaceae in previously noncolonized and noninfected patients and used the double disk synergy test for extended-spectrum beta-lactamase-producing Enterobacteriaceae phenotypic confirmation. Studies reporting extended-spectrum beta-lactamase-producing Enterobacteriaceae outbreaks or data on pediatric population were excluded. Two authors independently assessed study eligibility and performed data extraction. Thirteen studies (with 15,045 ICUs-patients) were evaluated using a random-effect model and a meta-regression analysis. The acquisition rate of digestive tract colonization during ICU stay was 7% (95% CI, 5-10) and it varies from 3% (95% CI, 2-4) and 4% (95% CI, 2-6) in the Americas and Europe to 21% (95% CI, 9-35) in the Western Pacific region. Previous hospitalization (risk ratio, 1.57 [95% CI, 1.07-2.31]) or antibiotic use (risk ratio, 1.65 [95% CI, 1.15-2.37]) and exposure to beta-lactams/beta-lactamase inhibitors (risk ratio, 1.78 [95% CI, 1.24-2.56]) and carbapenems (risk ratio, 2.13 [95% CI, 1.49-3.06]) during the ICU stay were independent risk factors for ICU-acquired colonization. Importantly, colonized patients were more likely to develop an extended-spectrum beta-lactamase-producing Enterobacteriaceae infection (risk ratio, 49.62 [95% CI, 20.42-120.58]). The sensitivity and specificity of prior colonization to predict subsequent extended-spectrum beta-lactamase-producing Enterobacteriaceae infection were 95.1% (95% CI, 54.7-99.7) and 89.2% (95% CI, 77.2-95.3), respectively. The ICU acquisition rate of extended-spectrum beta-lactamase-producing Enterobacteriaceae ranged from 5% to 10%. Previous use of beta-lactam/beta-lactamase or carbapenems and recent hospitalization were independent risk factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae colonization, and colonization was associated with significantly higher frequency of extended-spectrum beta-lactamase-producing Enterobacteriaceae subsequent infection and increased mortality.

Three-dimensional velocity models of the Mount St. Helens magmatic system using the iMUSH active-source data set

NASA Astrophysics Data System (ADS)

Kiser, E.; Levander, A.; Zelt, C. A.; Palomeras, I.; Creager, K.; Ulberg, C. W.; Schmandt, B.; Hansen, S. M.; Harder, S. H.; Abers, G. A.; Crosbie, K.

2017-12-01

Building upon previously published 2D results, this presentation will show the first 3D velocity models down to the Moho using the iMUSH (imaging Magma Under St. Helens) active-source seismic data set. Direct P and S wave travel times from 23 borehole shots recorded at approximately 6000 seismograph locations are used to model Vp, Vs, and Vp/Vs over an area extending approximately 75 km from the edifice of Mount St. Helens and down to approximately 15 km depth. At shallow depths, results show several high and low velocity anomalies that correspond well with known geological features. These include the Chehalis Basin northwest of Mount St. Helens, and the Silver Star Mountain, Spirit Lake, and Spud Mountain plutons. Starting at 4 km depth, low velocities and high Vp/Vs values are observed near Mount St. Helens, which may be associated with shallow magmatic fluids. High Vp/Vs values are also observed beneath the Indian Heaven Volcanic Field southeast of Mount St. Helens. At the regional scale, high amplitude north/south trending low and high velocity features extend from the western margin of the resolved models to approximately 30 km west of Mount St. Helens. In general these high and low velocity features also correspond to high and low Vp/Vs anomalies, respectively. These results are in agreement with previous studies that conclude that the accreted terrane Siletzia is composed of multiple igneous bodies interspersed with sedimentary units in this region. Another regional feature of interest is a broad low Vp/Vs area between Mount St. Helens, Mount Adams, and Mount Rainier that spatially correlates with the Southern Washington Cascades Conductor, indicating a non-magmatic origin to this body at shallow and mid-crustal depths. In addition to these shallow results, preliminary 3D velocity models of the entire crust will be presented that utilize both direct and reflected seismic phases from the Moho and other mid-crustal discontinuities. These models will constrain the lateral extents of lower-crustal high and low velocity features observed in previous 2D results. This information will be critical for understanding the distribution of cumulate bodies, magma reservoirs, and accreted terranes in the lower crust, and how these features have affected recent volcanic activity in this region.

Model-Based Engine Control Architecture with an Extended Kalman Filter

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.; Connolly, Joseph W.

2016-01-01

This paper discusses the design and implementation of an extended Kalman filter (EKF) for model-based engine control (MBEC). Previously proposed MBEC architectures feature an optimal tuner Kalman Filter (OTKF) to produce estimates of both unmeasured engine parameters and estimates for the health of the engine. The success of this approach relies on the accuracy of the linear model and the ability of the optimal tuner to update its tuner estimates based on only a few sensors. Advances in computer processing are making it possible to replace the piece-wise linear model, developed off-line, with an on-board nonlinear model running in real-time. This will reduce the estimation errors associated with the linearization process, and is typically referred to as an extended Kalman filter. The non-linear extended Kalman filter approach is applied to the Commercial Modular Aero-Propulsion System Simulation 40,000 (C-MAPSS40k) and compared to the previously proposed MBEC architecture. The results show that the EKF reduces the estimation error, especially during transient operation.

Model-Based Engine Control Architecture with an Extended Kalman Filter

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.; Connolly, Joseph W.

2016-01-01

This paper discusses the design and implementation of an extended Kalman filter (EKF) for model-based engine control (MBEC). Previously proposed MBEC architectures feature an optimal tuner Kalman Filter (OTKF) to produce estimates of both unmeasured engine parameters and estimates for the health of the engine. The success of this approach relies on the accuracy of the linear model and the ability of the optimal tuner to update its tuner estimates based on only a few sensors. Advances in computer processing are making it possible to replace the piece-wise linear model, developed off-line, with an on-board nonlinear model running in real-time. This will reduce the estimation errors associated with the linearization process, and is typically referred to as an extended Kalman filter. The nonlinear extended Kalman filter approach is applied to the Commercial Modular Aero-Propulsion System Simulation 40,000 (C-MAPSS40k) and compared to the previously proposed MBEC architecture. The results show that the EKF reduces the estimation error, especially during transient operation.

Extended hard-X-ray emission in the inner few parsecs of the Galaxy.

PubMed

Perez, Kerstin; Hailey, Charles J; Bauer, Franz E; Krivonos, Roman A; Mori, Kaya; Baganoff, Frederick K; Barrière, Nicolas M; Boggs, Steven E; Christensen, Finn E; Craig, William W; Grefenstette, Brian W; Grindlay, Jonathan E; Harrison, Fiona A; Hong, Jaesub; Madsen, Kristin K; Nynka, Melania; Stern, Daniel; Tomsick, John A; Wik, Daniel R; Zhang, Shuo; Zhang, William W; Zoglauer, Andreas

2015-04-30

The Galactic Centre hosts a puzzling stellar population in its inner few parsecs, with a high abundance of surprisingly young, relatively massive stars bound within the deep potential well of the central supermassive black hole, Sagittarius A* (ref. 1). Previous studies suggest that the population of objects emitting soft X-rays (less than 10 kiloelectronvolts) within the surrounding hundreds of parsecs, as well as the population responsible for unresolved X-ray emission extending along the Galactic plane, is dominated by accreting white dwarf systems. Observations of diffuse hard-X-ray (more than 10 kiloelectronvolts) emission in the inner 10 parsecs, however, have been hampered by the limited spatial resolution of previous instruments. Here we report the presence of a distinct hard-X-ray component within the central 4 × 8 parsecs, as revealed by subarcminute-resolution images in the 20-40 kiloelectronvolt range. This emission is more sharply peaked towards the Galactic Centre than is the surface brightness of the soft-X-ray population. This could indicate a significantly more massive population of accreting white dwarfs, large populations of low-mass X-ray binaries or millisecond pulsars, or particle outflows interacting with the surrounding radiation field, dense molecular material or magnetic fields. However, all these interpretations pose significant challenges to our understanding of stellar evolution, binary formation, and cosmic-ray production in the Galactic Centre.

Behavior and Body Patterns of the Larger Pacific Striped Octopus.

PubMed

Caldwell, Roy L; Ross, Richard; Rodaniche, Arcadio; Huffard, Christine L

2015-01-01

Over thirty years ago anecdotal accounts of the undescribed Larger Pacific Striped Octopus suggested behaviors previously unknown for octopuses. Beak-to-beak mating, dens shared by mating pairs, inking during mating and extended spawning were mentioned in publications, and enticed generations of cephalopod biologists. In 2012-2014 we were able to obtain several live specimens of this species, which remains without a formal description. All of the unique behaviors listed above were observed for animals in aquaria and are discussed here. We describe the behavior, body color patterns, and postures of 24 adults maintained in captivity. Chromatophore patterns of hatchlings are also shown.

Behavior and Body Patterns of the Larger Pacific Striped Octopus

PubMed Central

Caldwell, Roy L.; Ross, Richard; Rodaniche, Arcadio; Huffard, Christine L.

2015-01-01

Over thirty years ago anecdotal accounts of the undescribed Larger Pacific Striped Octopus suggested behaviors previously unknown for octopuses. Beak-to-beak mating, dens shared by mating pairs, inking during mating and extended spawning were mentioned in publications, and enticed generations of cephalopod biologists. In 2012–2014 we were able to obtain several live specimens of this species, which remains without a formal description. All of the unique behaviors listed above were observed for animals in aquaria and are discussed here. We describe the behavior, body color patterns, and postures of 24 adults maintained in captivity. Chromatophore patterns of hatchlings are also shown. PMID:26266543

On the large scale structure of X-ray background sources

NASA Technical Reports Server (NTRS)

Bi, H. G.; Meszaros, A.; Meszaros, P.

1991-01-01

The large scale clustering of the sources responsible for the X-ray background is discussed, under the assumption of a discrete origin. The formalism necessary for calculating the X-ray spatial fluctuations in the most general case where the source density contrast in structures varies with redshift is developed. A comparison of this with observational limits is useful for obtaining information concerning various galaxy formation scenarios. The calculations presented show that a varying density contrast has a small impact on the expected X-ray fluctuations. This strengthens and extends previous conclusions concerning the size and comoving density of large scale structures at redshifts 0.5 between 4.0.

Beyond the plane-parallel and Newtonian approach: wide-angle redshift distortions and convergence in general relativity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertacca, Daniele; Maartens, Roy; Raccanelli, Alvise

We extend previous analyses of wide-angle correlations in the galaxy power spectrum in redshift space to include all general relativistic effects. These general relativistic corrections to the standard approach become important on large scales and at high redshifts, and they lead to new terms in the wide-angle correlations. We show that in principle the new terms can produce corrections of nearly 10% on Gpc scales over the usual Newtonian approximation. General relativistic corrections will be important for future large-volume surveys such as SKA and Euclid, although the problem of cosmic variance will present a challenge in observing this.

Evolution of Structure and Composition in Saturn's Rings Due to Ballistic Transport of Micrometeoroid Impact Ejecta

NASA Astrophysics Data System (ADS)

Estrada, P. R.; Durisen, R. H.; Cuzzi, J. N.

2014-04-01

We introduce improved numerical techniques for simulating the structural and compositional evolution of planetary rings due to micrometeoroid bombardment and subsequent ballistic transport of impact ejecta. Our current, robust code, which is based on the original structural code of [1] and on the pollution transport code of [3], is capable of modeling structural changes and pollution transport simultaneously over long times on both local and global scales. We provide demonstrative simulations to compare with, and extend upon previous work, as well as examples of how ballistic transport can maintain the observed structure in Saturn's rings using available Cassini occultation optical depth data.

Water walking - an evolution of water surface skipping

NASA Astrophysics Data System (ADS)

Hurd, Randy; Belden, Jesse; Jandron, Michael; Bower, Allan; Holekamp, Sean; Truscott, Tadd

2017-11-01

Previous work has shown that elastomeric spheres skip more easily than disk-shaped stones. This is due to increased lift stemming from sphere deformation, which provides an increased cross-sectional area and favorable attack angle upon impact. We extend lift models developed for individual impacts to long-range multiple impact events and compare the estimates to experimental results, which show good agreement. Additionally, a surprising new mode of skipping is observed that resembles water-walking, wherein a quickly rotating sphere produces small successive impacts allowing it to move parallel to the water surface. The dynamics of this new multiple skip behavior are rationalized analytically and tested experimentally.

Spectral measurements of alpha-induced radioluminescence in various gases

NASA Astrophysics Data System (ADS)

Brett, Jaclyn; Koehler, Katrina E.; Bischak, Michael; Famiano, Michael; Jenkins, Jared; Klankowski, Levi; Niraula, Prashantamani; Pancella, Paul; Lakis, Rollin

2017-12-01

Radioluminescent emission in Ar, N2, O2, and dry air at P = 1 atm was observed induced by 5 MeV α particles. The wavelength range with a single detector spanned 250-1100 nm, extending the range well into the UV and IR bands with a single detector. Measured spectral lines for alpha-induced luminescence were corrected for detector transmission and intensities compared to previous work. The exploration of multiple gases over a wide frequency range opens the door to security and remote sensing applications, where different environments are routinely encountered. This work provides spectra that can be used in guiding future filter development focusing on remote alpha detection.

Directional x-ray dark-field imaging of strongly ordered systems

NASA Astrophysics Data System (ADS)

Jensen, Torben Haugaard; Bech, Martin; Zanette, Irene; Weitkamp, Timm; David, Christian; Deyhle, Hans; Rutishauser, Simon; Reznikova, Elena; Mohr, Jürgen; Feidenhans'L, Robert; Pfeiffer, Franz

2010-12-01

Recently a novel grating based x-ray imaging approach called directional x-ray dark-field imaging was introduced. Directional x-ray dark-field imaging yields information about the local texture of structures smaller than the pixel size of the imaging system. In this work we extend the theoretical description and data processing schemes for directional dark-field imaging to strongly scattering systems, which could not be described previously. We develop a simple scattering model to account for these recent observations and subsequently demonstrate the model using experimental data. The experimental data includes directional dark-field images of polypropylene fibers and a human tooth slice.

Characters and clues: Factors affecting children’s extension of knowledge through integration of separate episodes

PubMed Central

Bauer, Patricia J.; King, Jessica E.; Larkina, Marina; Varga, Nicole L.; White, Elizabeth A.

2012-01-01

Children build up knowledge about the world and also remember individual episodes. How individual episodes during which children learn new things become integrated with one another to form general knowledge is only beginning to be explored. Integration between separate episodes is called on in educational contexts and in everyday life as a major means of extending knowledge and organizing information. Bauer and San Souci (2010) provided an initial demonstration that 6-year-olds extend their knowledge by integrating between separate but related episodes; the episodes shared a high level of surface similarity. Experiments 1A and 1B of the current research were tests of integration under low and high levels of surface similarity, respectively. In Experiment 1A, when surface similarity of the episodes was low, 6-year-olds integrated between passages of text, yet their performance was not as robust as observed previously. In Experiment 1B, when surface similarity of the episodes was high, a replication of Bauer and San Souci’s results was observed. In Experiment 2, we tested whether a “hint” to consult the information learned in the passages improved performance even when surface level similarity was low. The hint had a strong facilitating effect. Possible mechanisms of integration between separate yet related episodes are discussed. PMID:22153911

Search for supersymmetry at $$\\sqrt{s}=13$$ TeV in final states with jets and two same-sign leptons or three leptons with the ATLAS detector

DOE PAGES

Aad, G.; Abbott, B.; Abdallah, J.; ...

2016-05-07

Here, a search for strongly produced supersymmetric particles is conducted using signatures involving multiple energetic jets and either two isolated leptons (e or μ) with the same electric charge or at least three isolated leptons. The search also utilises b-tagged jets, missing transverse momentum and other observables to extend its sensitivity. The analysis uses a data sample of proton–proton collisions at √s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015 corresponding to a total integrated luminosity of 3.2 fb –1. No significant excess over the Standard Model expectation is observed. The results aremore » interpreted in several simplified supersymmetric models and extend the exclusion limits from previous searches. In the context of exclusive production and simplified decay modes, gluino masses are excluded at 95% confidence level up to 1.1–1.3 TeV for light neutralinos (depending on the decay channel), and bottom squark masses are also excluded up to 540 GeV. In the former scenarios, neutralino masses are also excluded up to 550–850 GeV for gluino masses around 1 TeV.« less

CHEERS Results on Mrk 573: A Study of Deep Chandra Observations

NASA Astrophysics Data System (ADS)

Paggi, Alessandro; Wang, Junfeng; Fabbiano, Giuseppina; Elvis, Martin; Karovska, Margarita

2012-09-01

We present results on Mrk 573 obtained as part of the CHandra survey of Extended Emission-line Regions in nearby Seyfert galaxies (CHEERS). Previous studies showed that this source features a biconical emission in the soft X-ray band closely related to the narrow-line region as mapped by the [O III] emission line and the radio emission, though on a smaller scale; we investigate the properties of soft X-ray emission from this source with new deep Chandra observations. Making use of the subpixel resolution of the Chandra/ACIS image and point-spread function deconvolution, we resolve and study substructures in each ionizing cone. The two cone spectra are fitted with a photoionization model, showing a mildly photoionized phase diffused over the bicone. Thermal collisional gas at about ~1.1 keV and ~0.8 keV appears to be located between the nucleus and the "knots" resolved in radio observations, and between the "arcs" resolved in the optical images, respectively; this can be interpreted in terms of shock interaction with the host galactic plane. The nucleus shows a significant flux decrease across the observations indicating variability of the active galactic nucleus (AGN), with the nuclear region featuring a higher ionization parameter with respect to the bicone region. The long exposure allows us to find extended emission up to ~7 kpc from the nucleus along the bicone axis. Significant emission is also detected in the direction perpendicular to the ionizing cones, disagreeing with the fully obscuring torus prescribed in the AGN unified model and suggesting instead the presence of a clumpy structure.

Empirical Evidence for Roughness-Dependent Limit in Observation of Odd-Even Effect in Wetting Properties of Polar Liquids on n-Alkanethiolate Self-Assembled Monolayers.

PubMed

Wang, Zhengjia; Chen, Jiahao; Oyola-Reynoso, Stephanie; Thuo, Martin

2016-08-16

Substrate roughness influences the wetting properties of self-assembled monolayers (SAMs), but details on this dependency at the sub-nanometer level are still lacking. This study investigates the effect of surface roughness on interfacial properties of n-alkanethiolate SAMs, specifically wetting, and confirms the predicted limit to the observation of the odd-even effect in hydrophobicity. This article studies static contact angles of polar and nonpolar probe liquids on a series of n-alkanethiolate SAMs on surfaces with tunable roughness. We prepared Ag surfaces with root-mean-square roughness (Rrms) of ∼0.6-2.2 nm and compared the wetting properties of n-alkanethiolate SAMs fabricated on these surfaces. We measured the static contact angles, θs, formed between SAM and probe liquids [water, glycerol, and hexadecane]. Hexadecane showed an odd-even effect on all surfaces irrespective of the degree of roughness. Polar liquids (water and glycerol), however, showed a dependency on the roughness of the substrate with an odd-even effect observable only on smooth, but not rougher (Rrms ≥ 1.15 nm), surfaces. These results confirm that the previously predicted limit to observation of the odd-even effect in hydrophobicity (here extended to polar liquids) is real. From the results with glycerol, we infer that this limit is not limited just to hydrophobicity but may extend to other polar liquids. Results from hexadecane, however, suggest that this limit may not be a universal property of the SAM.

On the verification of intransitive noninterference in mulitlevel security.

PubMed

Ben Hadj-Alouane, Nejib; Lafrance, Stéphane; Lin, Feng; Mullins, John; Yeddes, Mohamed Moez

2005-10-01

We propose an algorithmic approach to the problem of verification of the property of intransitive noninterference (INI), using tools and concepts of discrete event systems (DES). INI can be used to characterize and solve several important security problems in multilevel security systems. In a previous work, we have established the notion of iP-observability, which precisely captures the property of INI. We have also developed an algorithm for checking iP-observability by indirectly checking P-observability for systems with at most three security levels. In this paper, we generalize the results for systems with any finite number of security levels by developing a direct method for checking iP-observability, based on an insightful observation that the iP function is a left congruence in terms of relations on formal languages. To demonstrate the applicability of our approach, we propose a formal method to detect denial of service vulnerabilities in security protocols based on INI. This method is illustrated using the TCP/IP protocol. The work extends the theory of supervisory control of DES to a new application domain.

Observation of Mountain Lee Waves with MODIS NIR Column Water Vapor

NASA Technical Reports Server (NTRS)

Lyapustin, A.; Alexander, M. J.; Ott, L.; Molod, A.; Holben, B.; Susskind, J.; Wang, Y.

2014-01-01

Mountain lee waves have been previously observed in data from the Moderate Resolution Imaging Spectroradiometer (MODIS) "water vapor" 6.7 micrometers channel which has a typical peak sensitivity at 550 hPa in the free troposphere. This paper reports the first observation of mountain waves generated by the Appalachian Mountains in the MODIS total column water vapor (CWV) product derived from near-infrared (NIR) (0.94 micrometers) measurements, which indicate perturbations very close to the surface. The CWV waves are usually observed during spring and late fall or some summer days with low to moderate CWV (below is approx. 2 cm). The observed lee waves display wavelengths from3-4 to 15kmwith an amplitude of variation often comparable to is approx. 50-70% of the total CWV. Since the bulk of atmospheric water vapor is confined to the boundary layer, this indicates that the impact of thesewaves extends deep into the boundary layer, and these may be the lowest level signatures of mountain lee waves presently detected by remote sensing over the land.

Blue compact dwarf galaxies. II - Near-infrared studies and stellar populations

NASA Technical Reports Server (NTRS)

Thuan, T. X.

1983-01-01

An IR photometric survey was performed of 36 blue compact dwarf galaxies (BCDG) where intense bursts of star formation have been observed. The survey covered the J, H, and K lines, with all readings taken at the level of a few mJy. Although the near-IR fluxes observed in the galaxies are due to K and M giants, the bursts have calculated ages of less than 50 million yr. However, the BCDG galaxies surveyed are not young, with the least chemically evolved galaxy observed, I Zw 18, featuring 50 pct of its stars formed prior to its last burst, but with a missing mass that is not accounted for by H I interferometric observations. It is concluded that the old stars must be more spatially extended than the young stars, and a mixture of OB stars with the K and M giants is projected as capable of displaying the colors observed. The star formation processes in the BCDG galaxies is defined as dependent on the total mass of the galaxies, with low mass galaxies having a high ratio of star formation, compared to their previous rates.

Kepler Flares. IV. A Comprehensive Analysis of the Activity of the dM4e Star GJ 1243

NASA Astrophysics Data System (ADS)

Silverberg, Steven M.; Kowalski, Adam F.; Davenport, James R. A.; Wisniewski, John P.; Hawley, Suzanne L.; Hilton, Eric J.

2016-10-01

We present a comprehensive study of the active dM4e star GJ 1243. We use previous observations and ground-based echelle spectroscopy to determine that GJ 1243 is a member of the Argus association of field stars, suggesting it is ∼ 30{--}50 {{Myr}} old. We analyze 11 months of 1 minute cadence data from Kepler, presenting Kepler flare frequency distributions, as well as determining correlations between flare energy, amplitude, duration, and decay time. We find that the exponent α of the power-law flare energy distribution varies in time, primarily due to completeness of sample and the low frequency of high-energy flares. We also find a deviation from a single power law at high energy. We use ground-based spectroscopic observations that were simultaneous with the Kepler data to provide simultaneous photometric and spectroscopic analysis of three low-energy flares, the lowest-energy dMe flares with detailed spectral analysis to date on any star. The spectroscopic data from these flares extend constraints for radiative hydrodynamic flare models to a lower energy regime than has previously been studied. We use this simultaneous spectroscopy and Kepler photometry to develop approximate conversions from the Kepler bandpass to the traditional U and B bands. This conversion will be a critical factor in comparing any Kepler flare analyses to the canon of previous ground-based flare studies.

A statistical study of whistler waves observed by Van Allen Probes (RBSP) and lightning detected by WWLLN

NASA Astrophysics Data System (ADS)

Zheng, Hao; Holzworth, Robert H.; Brundell, James B.; Jacobson, Abram R.; Wygant, John R.; Hospodarsky, George B.; Mozer, Forrest S.; Bonnell, John

2016-03-01

Lightning-generated whistler waves are electromagnetic plasma waves in the very low frequency (VLF) band, which play an important role in the dynamics of radiation belt particles. In this paper, we statistically analyze simultaneous waveform data from the Van Allen Probes (Radiation Belt Storm Probes, RBSP) and global lightning data from the World Wide Lightning Location Network (WWLLN). Data were obtained between July to September 2013 and between March and April 2014. For each day during these periods, we predicted the most probable 10 min for which each of the two RBSP satellites would be magnetically conjugate to lightning producing regions. The prediction method uses integrated WWLLN stroke data for that day obtained during the three previous years. Using these predicted times for magnetic conjugacy to lightning activity regions, we recorded high time resolution, burst mode waveform data. Here we show that whistlers are observed by the satellites in more than 80% of downloaded waveform data. About 22.9% of the whistlers observed by RBSP are one-to-one coincident with source lightning strokes detected by WWLLN. About 40.1% more of whistlers are found to be one-to-one coincident with lightning if source regions are extended out 2000 km from the satellites footpoints. Lightning strokes with far-field radiated VLF energy larger than about 100 J are able to generate a detectable whistler wave in the inner magnetosphere. One-to-one coincidences between whistlers observed by RBSP and lightning strokes detected by WWLLN are clearly shown in the L shell range of L = 1-3. Nose whistlers observed in July 2014 show that it may be possible to extend this coincidence to the region of L≥4.

Extended Edited Synoptic Cloud Reports from Ships and Land Stations Over the Globe, 1952-2009 (NDP-026C)

DOE Data Explorer

Hahn, C. J. [University of Arizona; Warren, S. G. [University of Washington; Eastman, R.

1999-08-01

This database contains surface synoptic weather reports for the entire globe, gathered from various available data sets. The reports were processed, edited, and rewritten to provide a single dataset of individual observations of clouds, spanning the 57 years 1952-2008 for ship data and the 39 years 1971-2009 for land station data. In addition to the cloud portion of the synoptic report, each edited report also includes the associated pressure, present weather, wind, air temperature, and dew point (and sea surface temperature over oceans). This data set is called the "Extended Edited Cloud Report Archive" (EECRA). The EECRA is based solely on visual cloud observations from weather stations, reported in the WMO synoptic code (WMO, 1974). Reports must contain cloud-type information to be included in the archive. Past data sources include those from the Fleet Numerical Oceanographic Center (FNOC, 1971-1976) and the National Centers for Environmental Prediction (NCEP, 1977-1996). This update uses data from a new source, the 'Integrated Surface Database' (ISD, 1997-2009; Smith et al., 2011). Our past analyses of the EECRA identified a subset of 5388 weather stations that were determined to produce reliable day and night observations of cloud amount and type. The update contains observations only from this subset of stations. Details concerning processing, previous problems, contents, and comments are available in the archive's original documentation . The EECRA contains about 81 million cloud observations from ships and 380 million from land stations. The data files have been compressed using unix. Unix/linux users can "uncompress" or "gunzip" the files after downloading. If you're interested in the NDP-026C database, then you'll also want to explore its related data products, NDP-026D and NDP-026E.

Evaluation of wave runup predictions from numerical and parametric models

USGS Publications Warehouse

Stockdon, Hilary F.; Thompson, David M.; Plant, Nathaniel G.; Long, Joseph W.

2014-01-01

Wave runup during storms is a primary driver of coastal evolution, including shoreline and dune erosion and barrier island overwash. Runup and its components, setup and swash, can be predicted from a parameterized model that was developed by comparing runup observations to offshore wave height, wave period, and local beach slope. Because observations during extreme storms are often unavailable, a numerical model is used to simulate the storm-driven runup to compare to the parameterized model and then develop an approach to improve the accuracy of the parameterization. Numerically simulated and parameterized runup were compared to observations to evaluate model accuracies. The analysis demonstrated that setup was accurately predicted by both the parameterized model and numerical simulations. Infragravity swash heights were most accurately predicted by the parameterized model. The numerical model suffered from bias and gain errors that depended on whether a one-dimensional or two-dimensional spatial domain was used. Nonetheless, all of the predictions were significantly correlated to the observations, implying that the systematic errors can be corrected. The numerical simulations did not resolve the incident-band swash motions, as expected, and the parameterized model performed best at predicting incident-band swash heights. An assimilated prediction using a weighted average of the parameterized model and the numerical simulations resulted in a reduction in prediction error variance. Finally, the numerical simulations were extended to include storm conditions that have not been previously observed. These results indicated that the parameterized predictions of setup may need modification for extreme conditions; numerical simulations can be used to extend the validity of the parameterized predictions of infragravity swash; and numerical simulations systematically underpredict incident swash, which is relatively unimportant under extreme conditions.

The tidally-modulated plume of Enceladus: an update

NASA Astrophysics Data System (ADS)

Nimmo, F.; Porco, C.; Mitchell, C. J.; Van Hoolst, T.; Hedman, M. M.

2016-12-01

The brightness of the ice grain plume of Enceladus is observed to vary on a diurnal timescale [1,2], consistent with predictions that the plume's mass is modulated by normal tidal stresses, which open and close cracks that reach the ocean [3]. Here we extend our previous analysis [2] to a larger set of ISS plume observations, including images taken since 2010, extending the temporal baseline by more than a factor of two. The observations were reduced using the same approach as in [2]. Fits were performed as in [2] but now include two different assumptions of how plume brightness responds to stresses [4] plus an updated calculation of the effects of long-period librations [5]. An apparent phase lag of 30-60 degrees between the modelled and observed response is robustly present, irrespective of the data set and assumptions used. This phase lag may be the result of the viscosity structure of the ice shell [2,4], an eruptive delay caused by the hydrodynamics within tidally-pumped cracks [6], or other as yet unknown processes. An earlier suggestion [2], that the phase lag is caused by the additional stresses arising from an 0.8 degree 1:1 physical libration in the moon's ice shell, can be rejected now that this libration has been measured with an amplitude of 0.12 degrees [7]. We also find in ISS images a secular decrease in plume brightness over the ten years of Cassini observations; this decrease may be due to long-period (forced) librations of Enceladus. [1] Hedman et al., Nature 2013 [2] Nimmo et al., Astron. J. 2014 [3] Hurford et al., Nature 2007 [4] Behounkova et al., Nature Geosci. 2015 [5] Yseboodt & Van Hoolst, Fall AGU, 2015 [6] Kite & Rubin, PNAS 2016 [7] Thomas et al., Icarus 2016

7 CFR 210.19 - Additional responsibilities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... this part, fiscal action shall be extended back to the beginning of the school year or that point in... severity and longevity of the problem, the State agency may extend fiscal action back to previous school... AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM Requirements for State Agency Participation...

7 CFR 210.19 - Additional responsibilities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... this part, fiscal action shall be extended back to the beginning of the school year or that point in... severity and longevity of the problem, the State agency may extend fiscal action back to previous school... AGRICULTURE CHILD NUTRITION PROGRAMS NATIONAL SCHOOL LUNCH PROGRAM Requirements for State Agency Participation...

Dorsal and ventral working memory-related brain areas support distinct processes in contextual cueing.

PubMed

Manginelli, Angela A; Baumgartner, Florian; Pollmann, Stefan

2013-02-15

Behavioral evidence suggests that the use of implicitly learned spatial contexts for improved visual search may depend on visual working memory resources. Working memory may be involved in contextual cueing in different ways: (1) for keeping implicitly learned working memory contents available during search or (2) for the capture of attention by contexts retrieved from memory. We mapped brain areas that were modulated by working memory capacity. Within these areas, activation was modulated by contextual cueing along the descending segment of the intraparietal sulcus, an area that has previously been related to maintenance of explicit memories. Increased activation for learned displays, but not modulated by the size of contextual cueing, was observed in the temporo-parietal junction area, previously associated with the capture of attention by explicitly retrieved memory items, and in the ventral visual cortex. This pattern of activation extends previous research on dorsal versus ventral stream functions in memory guidance of attention to the realm of attentional guidance by implicit memory. Copyright © 2012 Elsevier Inc. All rights reserved.

Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice.

PubMed

Good, Jeffrey M; Handel, Mary Ann; Nachman, Michael W

2008-01-01

House mice offer a powerful system for dissecting the genetic basis of phenotypes that isolate species in the early stages of speciation. We used a series of reciprocal crosses between wild-derived strains of Mus musculus and M. domesticus to examine F(1) hybrid male sterility, one of the primary phenotypes thought to isolate these species. We report four main results. First, we found significantly smaller testes and fewer sperm in hybrid male progeny of most crosses. Second, in some crosses hybrid male sterility was asymmetric and depended on the species origin of the X chromosome. These observations confirm and extend previous findings, underscoring the central role that the M. musculus X chromosome plays in reproductive isolation. Third, comparisons among reciprocal crosses revealed polymorphism at one or more hybrid incompatibilities within M. musculus. Fourth, the spermatogenic phenotype of this polymorphic interaction appears distinct from previously described hybrid incompatibilities between these species. These data build on previous studies of speciation in house mice and show that the genetic basis of hybrid male sterility is fairly complex, even at this early stage of divergence.

The convergent and concurrent validity of trait-based prototype assessment of personality disorder categories in homeless persons.

PubMed

Samuel, Douglas B; Connolly, Adrian J; Ball, Samuel A

2012-09-01

The DSM-5 proposal indicates that personality disorders (PDs) be defined as collections of maladaptive traits but does not provide a specific diagnostic method. However, researchers have previously suggested that PD constructs can be assessed by comparing individuals' trait profiles with those prototypic of PDs and evidence from the five-factor model (FFM) suggests that these prototype matching scores converge moderately with traditional PD instruments. The current study investigates the convergence of FFM PD prototypes with interview-assigned PD diagnoses in a sample of 99 homeless individuals. This sample had very high rates of PDs, which extends previous research on samples with more modest prevalence rates. Results indicated that diagnostic agreement between these methods was generally low but consistent with the agreement previously observed between explicit PD measures. Furthermore, trait-based and diagnostic interview scores evinced similar relationships with clinically important indicators such as abuse history and past suicide attempts. These findings demonstrate the validity of prototype methods and suggest their consideration for assessing trait-defined PD types within DSM-5.

The Elusive Soft Emission from Hard X-ray Symbiotic System RT Cru

NASA Astrophysics Data System (ADS)

Karovska, Margarita

2014-09-01

RT Cru is a fascinating member of a new class of hard X-ray emitting symbiotic binaries showing X-ray emission extending to over 50keV. While its hard X-ray emission has been studied in detail, the soft component of the spectrum, including flares, remains elusive, since previous observations have focused on the high-energy regime. We propose Chandra HRC-S/LETG observations to determine the spatial, spectral, and temporal characteristics of the source of the soft X-ray emission with a goal to establish the origin of the soft component, and determine whether and how it is tied to the hard component. Determining the origin of the soft emission is a crucial piece of the puzzle to understanding the geometry, energetics, and the environment of WD accretion in this class of symbiotic systems.

Dust disks around Vega-type stars

NASA Astrophysics Data System (ADS)

Chini, R.; Kruegel, E.; Kreysa, E.; Shustov, B.; Tutukov, A.

1991-12-01

This study presents 1300-micron observations of the circumstellar dust around Vega-type stars. A comparison of the new data (24-arcsec HPBW) for Alpha PsA, Tau-1 Eri and Epsilon Eri with previous measurements made at an angular resolution of 11-arcsec shows that the dust emission is extended. From measurements at different positions it is concluded that the circumstellar dust around Beta Pic does not exceed the size of the optical disk of 500 AU. A model for Beta Pic that fits optical as well as IR data is discussed. Finally, a scenario for the evolution of circumstellar grains is suggested where, on one side, the Poynting-Robertson effect removes the small particles and, on the other side, collisions lead to the formation of larger bodies. Time-dependent IR spectra in reasonable agreement with observations are presented.

A marked decrease in bispectral index with elevation of suppression ratio by cervical haematoma reducing cerebral perfusion pressure.

PubMed

Umegaki, N; Hirota, K; Kitayama, M; Yatsu, Y; Ishihara, H; Mtasuki, A

2003-11-01

A 77-year-old man with a ruptured abdominal aortic aneurysm undergoing aneurysmectomy were anaesthetised with ketamine under bispectral index (BIS) monitoring, which is a clinical EEG monitor for measurement of depth of anaesthesia/sedation. First marked BIS reduction with elevation of suppression ratio (SR) was observed following severe hypotension by deflation of the aortic occlusion balloon. The re-inflation and rapid blood transfusion improved haemodyanamics and BIS and SR. At second marked BIS reduction with SR elevation, a heavy cervical swelling due to a massive subcutaneous haematoma around the previously mis-punctured right carotid artery extending throughout the whole neck was observed without hypotension. Cervical relief incision improved the BIS and SR. The present case suggests that BIS monitor may be a simple and convenient monitor for cerebral ischaemia detection.

Effects of ambient turbulence on the near wake of a wind turbine

NASA Astrophysics Data System (ADS)

Kim, Yusik; Jost, Eva; Bangga, Galih; Weihing, Pascal; Lutz, Thorsten

2016-09-01

Developments of the near wake behind the Avatar research turbine (radius of 102.88 m) in ambient turbulence are investigated using high fidelity numerical simulations. A moderate level of background turbulence with a wide range of scales, which has not been considered in the previous studies is applied. With ambient turbulence, a significant impact on the near wake development is observed. The mean velocity profile becomes Gaussian after 450 m distance downstream, which is a demarcation between the near and the far wake. From the spectral analysis of the wake, clear peaks in the spectra are observed at the blade passing frequency, but the distributions of the peak extend into a wide range of frequency domain. Such aspects provide useful information in classifying periodic and stochastic fluctuations, and their contributions to the momentum mixing in the wake.

The evolving magnetic topology of τ Boötis

NASA Astrophysics Data System (ADS)

Mengel, M. W.; Fares, R.; Marsden, S. C.; Carter, B. D.; Jeffers, S. V.; Petit, P.; Donati, J.-F.; Folsom, C. P.; BCool Collaboration

2016-07-01

We present six epochs of spectropolarimetric observations of the hot-Jupiter-hosting star τ Boötis that extend the exceptional previous multiyear data set of its large-scale magnetic field. Our results confirm that the large-scale magnetic field of τ Boötis varies cyclicly, with the observation of two further magnetic reversals; between 2013 December and 2014 May and between 2015 January and March. We also show that the field evolves in a broadly solar-type manner in contrast to other F-type stars. We further present new results which indicate that the chromospheric activity cycle and the magnetic activity cycles are related, which would indicate a very rapid magnetic cycle. As an exemplar of long-term magnetic field evolution, τ Boötis and this long-term monitoring campaign presents a unique opportunity for studying stellar magnetic cycles.

A single sample study of dissociation between expressed and experienced pleasure by gender in mild depression.

PubMed

Brown, S L

Thirty male and thirty female adult subjects were divided equally into three groups on the basis of the Zung Self-Rating Depression Scale; mildly depressed (50-63), normal (40-49), and "low normal" (20-39). Observer ratings of positive affect were made during a one and one-half hour laboratory experiment, and self-ratings of pleasurable experience were collected at the end of the experiment. Results showed no significant differences between groups for self-report of experienced pleasure. However, a significant difference between groups was found for observer ratings of positive affect, with the mildly depressed and "low normal" subjects showing a shorter duration and a lower degree of positive affect than the normals. These results partially replicate and extended previous work. Implications for theory, research, and psychotherapy are discussed.

The STREGA survey - II. Globular cluster Palomar 12

NASA Astrophysics Data System (ADS)

Musella, I.; Di Criscienzo, M.; Marconi, M.; Raimondo, G.; Ripepi, V.; Cignoni, M.; Bono, G.; Brocato, E.; Dall'Ora, M.; Ferraro, I.; Grado, A.; Iannicola, G.; Limatola, L.; Molinaro, R.; Moretti, M. I.; Stetson, P. B.; Capaccioli, M.; Cioni, M.-R. L.; Getman, F.; Schipani, P.

2018-01-01

In the framework of the STREGA (STRucture and Evolution of the GAlaxy) survey, two fields around the globular cluster Pal 12 were observed with the aim of detecting the possible presence of streams and/or an extended halo. The adopted stellar tracers are the main sequence, turn-off and red giant branch stars. We discuss the luminosity function and the star counts in the observed region covering about 2 tidal radii, confirming that Pal 12 appears to be embedded in the Sagittarius Stream. Adopting an original approach to separate cluster and field stars, we do not find any evidence of significant extra-tidal Pal 12 stellar populations. The presence of the Sagittarius stream seems to have mimicked a larger tidal radius in previous studies. Indeed, adopting a King model, a redetermination of this value gives rT = 0.22 ± 0.1 deg.

An Improved Instrument for Investigating Planetary Regolith Microstructure

NASA Technical Reports Server (NTRS)

Nelson, R. M.; Hapke, B. W.; Smythe, W. D.; Manatt, K. S.; Eddy, J.

2005-01-01

The Opposition Effect (OE) is the non-linear increase in the intensity of light scattered from a surface as phase angle approaches 0 deg. It is seen in laboratory experiments and in remote sensing observations of planetary surfaces. Understanding the OE is a requirement for fitting photometric models which produce meaningful results about regolith texture. Previously we have reported measurements from the JPL long arm goniometer and we have shown that this instrument enables us to distinguish between two distinct processes which create the opposition surges, Shadow Hiding (SHOE) and Coherent Backscattering (CBOE). SHOE arises because, as phase angle approaches zero, shadows cast by regolith grains on other grains become invisible to the observer. CBOE results from constructive interference between rays traveling the same path but in opposite directions. Additional information is included in the original extended abstract.

Electron impact collision strengths in Ne VII

DOE Office of Scientific and Technical Information (OSTI.GOV)

Di, L.; Shi, J.R.; Zhao, G., E-mail: gzhao@bao.ac.cn

2012-07-15

The lines of Ne VII have been observed in many astronomical objects, and some transitions from high energy levels were observed both in Seyfert galaxies and stellar coronae. Thus, the atomic data for these transitions are important for modeling. Using the code FAC we calculated the collision strengths based on the distorted-wave method with large configuration interactions included. The Maxwellian averaged effective collision strengths covering the typical temperature range of astronomical and laboratory hot plasmas are presented. We extend the calculation of the energy levels to n=4 and 5. The energy levels, wavelengths, spontaneous transition rates, weighted oscillator strengths, andmore » effective collision strengths were reported. Compared with the results from experiment or previous theoretical calculations a general agreement is found. It is found that the resonance effects are important in calculating the effective collision strengths.« less

Diagnosing depression after stroke.

PubMed

Black, K J

1995-07-01

Neurobehavioral sequelae of strokes can limit a patient's ability to describe or express emotion, can cause him to give "yes" answers to the clinician who expects them, or can directly cause apathy or crying spells. Also, anosognosia for depressive signs can cause the patient to deny depressive signs that are objectively observable. These diagnostic confounders have not been adequately assessed in previous research on poststroke depression; thus many studies are of doubtful validity, as shown by studies of the dexamethasone suppression test for melancholia in stroke patients. Future studies on depression after stroke must prospectively rule out fluent aphasia, motor aprosody, and amnesia before relying on diagnostic information from the psychiatric interview, and the interview should always be supplemented by direct observation of vegetative signs and other behavior. With this extended information, major depression can and should be diagnosed using accepted symptom and duration criteria.

The HOSTS Survey—Exozodiacal Dust Measurements for 30 Stars

NASA Astrophysics Data System (ADS)

Ertel, S.; Defrère, D.; Hinz, P.; Mennesson, B.; Kennedy, G. M.; Danchi, W. C.; Gelino, C.; Hill, J. M.; Hoffmann, W. F.; Rieke, G.; Shannon, A.; Spalding, E.; Stone, J. M.; Vaz, A.; Weinberger, A. J.; Willems, P.; Absil, O.; Arbo, P.; Bailey, V. P.; Beichman, C.; Bryden, G.; Downey, E. C.; Durney, O.; Esposito, S.; Gaspar, A.; Grenz, P.; Haniff, C. A.; Leisenring, J. M.; Marion, L.; McMahon, T. J.; Millan-Gabet, R.; Montoya, M.; Morzinski, K. M.; Pinna, E.; Power, J.; Puglisi, A.; Roberge, A.; Serabyn, E.; Skemer, A. J.; Stapelfeldt, K.; Su, K. Y. L.; Vaitheeswaran, V.; Wyatt, M. C.

2018-05-01

The Hunt for Observable Signatures of Terrestrial Systems survey searches for dust near the habitable zones (HZs) around nearby, bright main-sequence stars. We use nulling interferometry in the N band to suppress the bright stellar light and to probe for low levels of HZ dust around the 30 stars observed so far. Our overall detection rate is 18%, including four new detections, among which are the first three around Sun-like stars and the first two around stars without any previously known circumstellar dust. The inferred occurrence rates are comparable for early-type and Sun-like stars, but decrease from {60}-21+16% for stars with previously detected cold dust to {8}-3+10% for stars without such excess, confirming earlier results at higher sensitivity. For completed observations on individual stars, our sensitivity is five to ten times better than previous results. Assuming a lognormal excess luminosity function, we put upper limits on the median HZ dust level of 13 zodis (95% confidence) for a sample of stars without cold dust and of 26 zodis when focusing on Sun-like stars without cold dust. However, our data suggest that a more complex luminosity function may be more appropriate. For stars without detectable Large Binocular Telescope Interferometer (LBTI) excess, our upper limits are almost reduced by a factor of two, demonstrating the strength of LBTI target vetting for future exo-Earth imaging missions. Our statistics are limited so far, and extending the survey is critical to informing the design of future exo-Earth imaging surveys.

Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction.

PubMed

Seyed-Razavi, Yashar; Hickey, Michael J; Kuffová, Lucia; McMenamin, Paul G; Chinnery, Holly R

2013-01-01

Membrane nanotubes (MNTs) are newly discovered cellular extensions that are either blind-ended or can connect widely separated cells. They have predominantly been investigated in cultured isolated cells, however, previously we were the first group to demonstrate the existence of these structures in vivo in intact mammalian tissues. We previously demonstrated the frequency of both cell-cell or bridging MNTs and blind-ended MNTs was greatest between major histocompatibility complex (MHC) class II(+) cells during corneal injury or TLR ligand-mediated inflammation. The present study aimed to further explore the dynamics of MNT formation and their size, presence in another tissue, the dura mater, and response to stress factors and an active local viral infection of the murine cornea. Confocal live cell imaging of myeloid-derived cells in inflamed corneal explants from Cx(3)cr1(GFP) and CD11c(eYFP) transgenic mice revealed that MNTs form de novo at a rate of 15.5 μm/min. This observation contrasts with previous studies that demonstrated that in vitro these structures originate from cell-cell contacts. Conditions that promote formation of MNTs include inflammation in vivo and cell stress due to serum starvation ex vivo. Herpes simplex virus-1 infection did not cause a significant increase in MNT numbers in myeloid cells in the cornea above that observed in injury controls, confirming that corneal epithelium injury alone elicits MNT formation in vivo. These novel observations extend the currently limited understanding of MNTs in live mammalian tissues.

Attribute-driven transfer learning for detecting novel buried threats with ground-penetrating radar

NASA Astrophysics Data System (ADS)

Colwell, Kenneth A.; Collins, Leslie M.

2016-05-01

Ground-penetrating radar (GPR) technology is an effective method of detecting buried explosive threats. The system uses a binary classifier to distinguish "targets", or buried threats, from "nontargets" arising from system prescreener false alarms; this classifier is trained on a dataset of previously-observed buried threat types. However, the threat environment is not static, and new threat types that appear must be effectively detected even if they are not highly similar to every previously-observed type. Gathering a new dataset that includes a new threat type is expensive and time-consuming; minimizing the amount of new data required to effectively detect the new type is therefore valuable. This research aims to reduce the number of training examples needed to effectively detect new types using transfer learning, which leverages previous learning tasks to accelerate and improve new ones. Further, new types have attribute data, such as composition, components, construction, and size, which can be observed without GPR and typically are not explicitly included in the learning process. Since attribute tags for buried threats determine many aspects of their GPR representation, a new threat type's attributes can be highly relevant to the transfer-learning process. In this work, attribute data is used to drive transfer learning, both by using attributes to select relevant dataset examples for classifier fusion, and by extending a relevance vector machine (RVM) model to perform intelligent attribute clustering and selection. Classification performance results for both the attribute-only case and the low-data case are presented, using a dataset containing a variety of threat types.

Extension of Drosophila Lifespan by Rhodiola rosea Depends on Dietary Carbohydrate and Caloric Content in a Simplified Diet.

PubMed

Schriner, Samuel E; Coskun, Volkan; Hogan, Sean P; Nguyen, Cindy T; Lopez, Terry E; Jafari, Mahtab

2016-03-01

The root and rhizome extract of Rhodiola rosea has been extensively used in traditional medicine to improve physical and mental performance and to protect against stress. We, and others, have reported that R. rosea can extend lifespan in flies, worms, and yeast. We also previously found that the extract can act independently of dietary restriction (DR), a treatment that can extend lifespan in a range of model organisms. In flies, DR is implemented through a reduction in dietary yeast content. Here, we report that the ability of R. rosea extract to extend lifespan in flies is dependent on the carbohydrate and caloric content when supplemented with a simplified diet composed of yeast and sucrose. R. rosea extract elevated the sugar content in flies and down-regulated hexokinase expression, suggesting that it perturbs carbohydrate metabolism in flies. In our previous studies, bananas, barley malt, and corn syrup provided dietary carbohydrates, and R. rosea extract could extend lifespan with a range of caloric levels. We conclude that the lifespan-extending effect of R. rosea extract in flies is dependent on dietary carbohydrate and caloric contents coupled with an interaction with complex dietary components present in bananas, barley, or corn.

Extended image differencing for change detection in UAV video mosaics

NASA Astrophysics Data System (ADS)

Saur, Günter; Krüger, Wolfgang; Schumann, Arne

2014-03-01

Change detection is one of the most important tasks when using unmanned aerial vehicles (UAV) for video reconnaissance and surveillance. We address changes of short time scale, i.e. the observations are taken in time distances from several minutes up to a few hours. Each observation is a short video sequence acquired by the UAV in near-nadir view and the relevant changes are, e.g., recently parked or moved vehicles. In this paper we extend our previous approach of image differencing for single video frames to video mosaics. A precise image-to-image registration combined with a robust matching approach is needed to stitch the video frames to a mosaic. Additionally, this matching algorithm is applied to mosaic pairs in order to align them to a common geometry. The resulting registered video mosaic pairs are the input of the change detection procedure based on extended image differencing. A change mask is generated by an adaptive threshold applied to a linear combination of difference images of intensity and gradient magnitude. The change detection algorithm has to distinguish between relevant and non-relevant changes. Examples for non-relevant changes are stereo disparity at 3D structures of the scene, changed size of shadows, and compression or transmission artifacts. The special effects of video mosaicking such as geometric distortions and artifacts at moving objects have to be considered, too. In our experiments we analyze the influence of these effects on the change detection results by considering several scenes. The results show that for video mosaics this task is more difficult than for single video frames. Therefore, we extended the image registration by estimating an elastic transformation using a thin plate spline approach. The results for mosaics are comparable to that of single video frames and are useful for interactive image exploitation due to a larger scene coverage.

Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus.

PubMed

Demirci, F Yesim; Wang, Xingbin; Morris, David L; Feingold, Eleanor; Bernatsky, Sasha; Pineau, Christian; Clarke, Ann; Ramsey-Goldman, Rosalind; Manzi, Susan; Vyse, Timothy J; Kamboh, M I

2017-06-01

A major systemic lupus erythematosus (SLE) susceptibility locus lies within a common inversion polymorphism region (encompassing 3.8 - 4.5  Mb) located at 8p23. Initially implicated genes included FAM167A-BLK and XKR6 , of which BLK received major attention due to its known role in B-cell biology. Recently, additional SLE risk carried in non-inverted background was also reported. In this case -control study, we further investigated the 'extended' 8p23 locus (~ 4  Mb) where we observed multiple SLE signals and assessed these signals for their relation to the inversion affecting this region. The study involved a North American discovery data set ( ~ 1200  subjects) and a replication data set (> 10 000  subjects) comprising European-descent individuals. Meta-analysis of 8p23 SNPs, with p < 0.05 in both data sets, identified 51 genome-wide significant SNPs (p < 5.0 × 10 -8 ). While most of these SNPs were related to previously implicated signals ( XKR6-FAM167A-BLK subregion), our results also revealed two 'new' SLE signals, including SGK223-CLDN23-MFHAS1 (6.06 × 10 -9 ≤ meta p ≤ 4.88 × 10 -8 ) and CTSB (meta p = 4.87 × 10 -8 ) subregions that are located > 2 Mb upstream and ~ 0.3  Mb downstream from previously reported signals. Functional assessment of relevant SNPs indicated putative cis -effects on the expression of various genes at 8p23. Additional analyses in discovery sample, where the inversion genotypes were inferred, replicated the association of non-inverted status with SLE risk and suggested that a number of SLE risk alleles are predominantly carried in non-inverted background. Our results implicate multiple (known+novel) SLE signals/genes at the extended 8p23 locus, beyond previously reported signals/genes, and suggest that this broad locus contributes to SLE risk through the effects of multiple genes/pathways. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Extended MHD Turbulence and Its Applications to the Solar Wind

NASA Astrophysics Data System (ADS)

Abdelhamid, Hamdi M.; Lingam, Manasvi; Mahajan, Swadesh M.

2016-10-01

Extended MHD is a one-fluid model that incorporates two-fluid effects such as electron inertia and the Hall drift. This model is used to construct fully nonlinear Alfvénic wave solutions, and thereby derive the kinetic and magnetic spectra by resorting to a Kolmogorov-like hypothesis based on the constant cascading rates of the energy and generalized helicities of this model. The magnetic and kinetic spectra are derived in the ideal (k\\lt 1/{λ }I), Hall (1/{λ }I\\lt k\\lt 1/{λ }e), and electron inertia (k\\gt 1/{λ }e) regimes; k is the wavenumber and {λ }s=c/{ω }{ps} is the skin depth of species “s.” In the Hall regime, it is shown that the emergent results are fully consistent with previous numerical and analytical studies, especially in the context of the solar wind. The focus is primarily on the electron inertia regime, where magnetic energy spectra with power-law indexes of -11/3 and -13/3 are always recovered. The latter, in particular, is quite close to recent observational evidence from the solar wind with a potential slope of approximately -4 in this regime. It is thus plausible that these spectra may constitute a part of the (extended) inertial range, as opposed to the standard “dissipation” range paradigm.

Extending ROSAT Light Curves of Ecliptic Pole AGN Formation and Galaxy Evolution

NASA Technical Reports Server (NTRS)

Malkan, Matthew A.

1997-01-01

In collaboration with UCLA graduate student Fred Baganoff, Professor Malkan has obtained the longest continuous light curves ever available for a large sample (# = 60) of active galactic nuclei. This was accomplished by using the ROSATAII-Sky Survey, which covered the ecliptic pole regions once every 9O-minute orbit. Using this Astrophysics Data Processing grant from NASA, we extended these light curves by combining the RASS data with pointed observations over the next several years of operation of the ROSAT PSPC. This lengthens the baselines of about half of the light curves from a few months up to a few years. The proportion of AGN showing variability increases substantially with this improvement. In fact most AGN in this representative sample are now shown to be significantly variable in the X-rays. We are also able to say something about the amplitudes of variability on timescales from days to years, with more detail than previously has been possible. We have also identified some dependence of the X-ray variability properties on a) the luminosity of the AGN; and b) The presence of a "Blazar" nucleus. By extending the ROSAT light curves, we are also able to learn more about the correlation of X-ray and optical emission on longer time-scales. It appears to be very weak, at best.

Generalised observer design for dissipative Lipschitz nonlinear systems in the presence of measurement noise

NASA Astrophysics Data System (ADS)

Vijayaraghavan, Krishna

2014-11-01

This paper presents two novel observer concepts. First, it develops a globally exponentially stable nonlinear observer for noise-free dissipative nonlinear systems. Second, for a dissipative nonlinear system with measurement noise, the paper develops an observer to guarantee a desired performance, namely an upper limit on the ratio of the square of the weighted L2 norm of the error to the square of the weighted L2 norm of the measurement noise. The necessary and sufficient conditions for both observers are reformulated as algebraic Riccati equations (AREs) so that standard solvers can be utilised. In addition, the paper presents necessary and sufficient conditions to be satisfied by the nonlinear system in order to ensure that the ARE (and hence the observer design problem) has a solution. The use of the methodology developed in this paper is demonstrated through illustrative examples. In literature, there is no previous observer for dissipative system that provides both necessary and sufficient conditions. Results for noisy system either rely on linearising the system about state trajectory (requiring initial estimates to be close to the actual states) or are for specialised systems that cannot be extended to dissipative systems.

A precessing jet in the NGC2264G outflow

NASA Astrophysics Data System (ADS)

McCoey, Carolyn; Teixeira, P. S.; Fich, M.; Lada, C. J.

2007-05-01

We present new infrared imaging of the NGC 2264 G protostellar outflow region, obtained with the Spitzer Space Telescope. A jet in the red (eastern) outflow lobe is clearly detected in all four IRAC bands and, for the first time, is shown to continuously extend over the entire length of the red outflow lobe, as traced by CO observations. The jet also extends to a deeply embedded Class 0 source, VLA2, confirming previous suggestions that it is the driving source of the outflow. The images show that the easternmost part of the jet exhibits what appears to be multiple changes of direction. We consider two possible explanations for the jet morphology: (i) deflection of the jet off the walls of the outflow lobes as proposed by Fich & Lada (1997) and (ii) precession. The jet structure shown in the IRAC images can be largely, although not entirely, explained by a slowly precessing jet (period 8000 yr) that lies mostly on the plane of the sky. In either case it appears that the observed and inferred changes in the jet direction are sufficient to broaden the NGC 2264 G outflow to an extent comparable to that observed in the CO emission. P. S. T. acknowledges support from the scholarship SFRH/BD/13984/2003 awarded by the Fundaçao para a Ciencia e Tecnologia (Portugal). Both M. F. and C. M. are supported by a Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant.

Exploring Expressive Vocabulary Variability in Two-Year-Olds: The Role of Working Memory.

PubMed

Newbury, Jayne; Klee, Thomas; Stokes, Stephanie F; Moran, Catherine

2015-12-01

This study explored whether measures of working memory ability contribute to the wide variation in 2-year-olds' expressive vocabulary skills. Seventy-nine children (aged 24-30 months) were assessed by using standardized tests of vocabulary and visual cognition, a processing speed measure, and behavioral measures of verbal working memory and phonological short-term memory. Strong correlations were observed between phonological short-term memory, verbal working memory, and expressive vocabulary. Speed of spoken word recognition showed a moderate significant correlation with expressive vocabulary. In a multivariate regression model for expressive vocabulary, the most powerful predictor was a measure of phonological short-term memory (accounting for 66% unique variance), followed by verbal working memory (6%), sex (2%), and age (1%). Processing speed did not add significant unique variance. These findings confirm previous research positing a strong role for phonological short-term memory in early expressive vocabulary acquisition. They also extend previous research in two ways. First, a unique association between verbal working memory and expressive vocabulary in 2-year-olds was observed. Second, processing speed was not a unique predictor of variance in expressive vocabulary when included alongside measures of working memory.

Positron elastic scattering from alkaline earth targets

NASA Astrophysics Data System (ADS)

Poveda, Luis A.; Assafrão, Denise; Mohallem, José R.

2016-07-01

A previously reported model potential approach [Poveda et al., Phys. Rev. A 87, 052702 (2013)] was extended to study low energy positron elastic scattering from beryllium and magnesium. The cross sections were computed for energies ranging from 10-5 eV up to well above the positronium formation threshold. The present results are in good agreement with previous reports, including the prediction of a p-wave resonance in the cross section for magnesium. The emergence of this shape resonance is connected to a trend observed in the evolution of the partial wave cross section in going from Be to Mg target. This trend lead us to speculate that a sharp d-wave resonance should be observed in positron elastic scattering from calcium. The positron-target binding energies are investigated in detail, both using the scattering information and by direct computation of the bound state energies using the model potentials. Contribution to the Topical Issue "Advances in Positron and Electron Scattering", edited by Paulo Limao-Vieira, Gustavo Garcia, E. Krishnakumar, James Sullivan, Hajime Tanuma and Zoran Petrovic.Supplementary material in the form of one pdf file available from the Journal web page at http://dx.doi.org/10.1140/epjd/e2016-70120-y

Neural Correlates of Sexual Orientation in Heterosexual, Bisexual, and Homosexual Men

PubMed Central

Safron, Adam; Sylva, David; Klimaj, Victoria; Rosenthal, A. M.; Li, Meng; Walter, Martin; Bailey, J. Michael

2017-01-01

Studies of subjective and genital sexual arousal in monosexual (i.e. heterosexual and homosexual) men have repeatedly found that erotic stimuli depicting men’s preferred sex produce strong responses, whereas erotic stimuli depicting the other sex produce much weaker responses. Inconsistent results have previously been obtained in bisexual men, who have sometimes demonstrated distinctly bisexual responses, but other times demonstrated patterns more similar to those observed in monosexual men. We used fMRI to investigate neural correlates of responses to erotic pictures and videos in heterosexual, bisexual, and homosexual men, ages 25–50. Sixty participants were included in video analyses, and 62 were included in picture analyses. We focused on the ventral striatum (VS), due to its association with incentive motivation. Patterns were consistent with sexual orientation, with heterosexual and homosexual men showing female-favoring and male-favoring responses, respectively. Bisexual men tended to show less differentiation between male and female stimuli. Consistent patterns were observed in the whole brain, including the VS, and also in additional regions such as occipitotemporal, anterior cingulate, and orbitofrontal cortices. This study extends previous findings of gender-specific neural responses in monosexual men, and provides initial evidence for distinct brain activity patterns in bisexual men. PMID:28145518

Dermal uptake of phthalates from clothing: Comparison of model to human participant results.

PubMed

Morrison, G C; Weschler, C J; Bekö, G

2017-05-01

In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate and di-n-butylphthalate (DnBP) than a previous model. The model predictions are consistent with the observation that previously exposed clothing can increase dermal uptake over that observed in bare-skin participants for the same exposure air concentrations. The model predicts that dermal uptake from clothing of DnBP is a substantial fraction of total uptake from all sources of exposure. For compounds that have high dermal permeability coefficients, dermal uptake is increased for (i) thinner clothing, (ii) a narrower gap between clothing and skin, and (iii) longer time intervals between laundering and wearing. Enhanced dermal uptake is most pronounced for compounds with clothing-air partition coefficients between 10 4 and 10 7 . In the absence of direct measurements of cotton cloth-air partition coefficients, dermal exposure may be predicted using equilibrium data for compounds in equilibrium with cellulose and water, in combination with computational methods of predicting partition coefficients. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Analyses of electron runaway in front of the negative streamer channel

NASA Astrophysics Data System (ADS)

Babich, L. P.; Bochkov, E. I.; Kutsyk, I. M.; Neubert, T.; Chanrion, O.

2017-08-01

X-ray and γ-ray emissions, observed in correlation with negative leaders of lightning and long sparks of high-voltage laboratory experiments, are conventionally connected with the bremsstrahlung of high-energy runaway electrons (REs). Here we extend a focusing mechanism, analyzed in our previous paper, which allows the electric field to reach magnitudes, required for a generation of significant RE fluxes and associated bremsstrahlung, when the ionization wave propagates in a narrow, ionized channel created by a previous streamer. Under such conditions we compute the production rate of REs per unit streamer length as a function of the streamer velocity and predict that, once a streamer is formed with the electric field capable of producing REs ahead of the streamer front, the ionization induced by the REs is capable of creating an ionized channel that allows for self-sustained propagation of the RE-emitting ionization wave independent of the initial electron concentration. Thus, the streamer coronas of the leaders are probable sources of REs producing the observed high-energy radiation. To prove these predictions, new simulations are planned, which would show explicitly that the preionization in front of the channel via REs will lead to the ionization wave propagation self-consistent with RE generation.

Probing Pre-Supernova Mass Loss With Circumstellar Dust Shells

NASA Astrophysics Data System (ADS)

Fox, Ori; Filippenko, Alex; Skrutskie, Mike; van Dyk, Schuyler; Kelly, Pat

2014-12-01

Late-time (>100 day) mid-infrared (mid-IR) observations of supernovae (SNe) offer a valuable probe of the progenitor system's mass-loss. Already, this technique has been demonstrated with the Type IIn subclass, which often have large, dusty, pre-existing shells formed in pre-SN eruptions. While other SN subclasses are thought of having relatively low density circumstellar environments, a growing number of objects in other subclasses now show evidence for significant pre-SN mass loss and similar mid-IR characteristics. Long after the SN radioactive tail fades, warm dust can stay bright at mid-IR wavelengths due to alternative heating mechanisms, such as shocks. Here we propose a SNAPSHOT survey of a well-studied and high-profile SN sample, extending over a range of subclasses, including both recent and historical events with evidence of a dense CSM and/or dust. This program will (a) discover new SNe with warm dust and (b) monitor the evolution of warm dust in previously detected SNe. Harnessing the success of our previous Spitzer programs, these observations will expand upon that work by probing the similarities in and differences between the subclasses' circumstellar environments, pre-SN mass-loss, and ultimately, the progenitors themselves.

Neural Correlates of Sexual Orientation in Heterosexual, Bisexual, and Homosexual Men.

PubMed

Safron, Adam; Sylva, David; Klimaj, Victoria; Rosenthal, A M; Li, Meng; Walter, Martin; Bailey, J Michael

2017-02-01

Studies of subjective and genital sexual arousal in monosexual (i.e. heterosexual and homosexual) men have repeatedly found that erotic stimuli depicting men's preferred sex produce strong responses, whereas erotic stimuli depicting the other sex produce much weaker responses. Inconsistent results have previously been obtained in bisexual men, who have sometimes demonstrated distinctly bisexual responses, but other times demonstrated patterns more similar to those observed in monosexual men. We used fMRI to investigate neural correlates of responses to erotic pictures and videos in heterosexual, bisexual, and homosexual men, ages 25-50. Sixty participants were included in video analyses, and 62 were included in picture analyses. We focused on the ventral striatum (VS), due to its association with incentive motivation. Patterns were consistent with sexual orientation, with heterosexual and homosexual men showing female-favoring and male-favoring responses, respectively. Bisexual men tended to show less differentiation between male and female stimuli. Consistent patterns were observed in the whole brain, including the VS, and also in additional regions such as occipitotemporal, anterior cingulate, and orbitofrontal cortices. This study extends previous findings of gender-specific neural responses in monosexual men, and provides initial evidence for distinct brain activity patterns in bisexual men.

An extension to artifact-free projection overlaps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Jianyu, E-mail: jianyulin@hotmail.com

2015-05-15

Purpose: In multipinhole single photon emission computed tomography, the overlapping of projections has been used to increase sensitivity. Avoiding artifacts in the reconstructed image associated with projection overlaps (multiplexing) is a critical issue. In our previous report, two types of artifact-free projection overlaps, i.e., projection overlaps that do not lead to artifacts in the reconstructed image, were formally defined and proved, and were validated via simulations. In this work, a new proposition is introduced to extend the previously defined type-II artifact-free projection overlaps so that a broader range of artifact-free overlaps is accommodated. One practical purpose of the new extensionmore » is to design a baffle window multipinhole system with artifact-free projection overlaps. Methods: First, the extended type-II artifact-free overlap was theoretically defined and proved. The new proposition accommodates the situation where the extended type-II artifact-free projection overlaps can be produced with incorrectly reconstructed portions in the reconstructed image. Next, to validate the theory, the extended-type-II artifact-free overlaps were employed in designing the multiplexing multipinhole spiral orbit imaging systems with a baffle window. Numerical validations were performed via simulations, where the corresponding 1-pinhole nonmultiplexing reconstruction results were used as the benchmark for artifact-free reconstructions. The mean square error (MSE) was the metric used for comparisons of noise-free reconstructed images. Noisy reconstructions were also performed as part of the validations. Results: Simulation results show that for noise-free reconstructions, the MSEs of the reconstructed images of the artifact-free multiplexing systems are very similar to those of the corresponding 1-pinhole systems. No artifacts were observed in the reconstructed images. Therefore, the testing results for artifact-free multiplexing systems designed using the extended type-II artifact-free overlaps numerically validated the developed theory. Conclusions: First, the extension itself is of theoretical importance because it broadens the selection range for optimizing multiplexing multipinhole designs. Second, the extension has an immediate application: using a baffle window to design a special spiral orbit multipinhole imaging system with projection overlaps in the orbit axial direction. Such an artifact-free baffle window design makes it possible for us to image any axial portion of interest of a long object with projection overlaps to increase sensitivity.« less

Long-term outcomes and recurrence patterns of standard versus extended pancreatectomy for pancreatic head cancer: a multicenter prospective randomized controlled study.

PubMed

Jang, Jin-Young; Kang, Jae Seung; Han, Youngmin; Heo, Jin Seok; Choi, Seong Ho; Choi, Dong Wook; Park, Sang Jae; Han, Sung-Sik; Yoon, Dong Sup; Park, Joon Seong; Yu, Hee Chul; Kang, Koo Jeong; Kim, Sang Geol; Lee, Hongeun; Kwon, Wooil; Yoon, Yoo-Seok; Han, Ho-Seong; Kim, Sun-Whe

2017-07-01

Our previous randomized controlled trial revealed no difference in 2-year overall survival (OS) between extended and standard resection for pancreatic adenocarcinoma. The present study evaluated the 5-year OS and recurrence patterns according to the extent of pancreatectomy. Between 2006 and 2009, 169 consecutive patients were prospectively enrolled and randomized to standard (n = 83) or extended resection (n = 86) groups to compare 5-year OS rate, long-term recurrence patterns and factors associated with long-term survival. The surgical R0 rate was similar between the standard and extended groups (85.5 vs. 90.7%, P = 0.300). Five-year OS (18.4 vs. 14.4%, P = 0.388), 5-year disease-free survival (14.8 vs. 14.0%, P = 0.531), and overall recurrence rates (74.7 vs. 69.9%, P = 0.497) were not significantly different between the two groups, although the incidence of peritoneal seeding was higher in the extended group (25 vs. 8.1%, P = 0.014). Extended pancreatectomy does not have better short-term and long-term survival outcomes, and shows similar R0 rates and overall recurrence rates compared with standard pancreatectomy. Extended pancreatectomy does not have to be performed routinely for all cases of resectable pancreatic adenocarcinoma, especially considering its associated increased morbidity shown in our previous study. © 2017 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

Evaluation of SAMe-TT2R2 Score on Predicting Success With Extended-Interval Warfarin Monitoring.

PubMed

Hwang, Andrew Y; Carris, Nicholas W; Dietrich, Eric A; Gums, John G; Smith, Steven M

2018-06-01

In patients with stable international normalized ratios, 12-week extended-interval warfarin monitoring can be considered; however, predictors of success with this strategy are unknown. The previously validated SAMe-TT 2 R 2 score (considering sex, age, medical history, treatment, tobacco, and race) predicts anticoagulation control during standard follow-up (every 4 weeks), with lower scores associated with greater time in therapeutic range. To evaluate the ability of the SAMe-TT 2 R 2 score in predicting success with extended-interval warfarin follow-up in patients with previously stable warfarin doses. In this post hoc analysis of a single-arm feasibility study, baseline SAMe-TT 2 R 2 scores were calculated for patients with ≥1 extended-interval follow-up visit. The primary analysis assessed achieved weeks of extended-interval follow-up according to baseline SAMe-TT 2 R 2 scores. A total of 47 patients receiving chronic anticoagulation completed a median of 36 weeks of extended-interval follow-up. The median baseline SAMe-TT 2 R 2 score was 1 (range 0-5). Lower SAMe-TT 2 R 2 scores appeared to be associated with greater duration of extended-interval follow-up achieved, though the differences between scores were not statistically significant. No individual variable of the SAMe-TT 2 R 2 score was associated with achieved weeks of extended-interval follow-up. Analysis of additional patient factors found that longer duration (≥24 weeks) of prior stable treatment was significantly associated with greater weeks of extended-interval follow-up completed ( P = 0.04). Conclusion and Relevance: This pilot study provides limited evidence that the SAMe-TT 2 R 2 score predicts success with extended-interval warfarin follow-up but requires confirmation in a larger study. Further research is also necessary to establish additional predictors of successful extended-interval warfarin follow-up.

Genetic and transcriptomic analyses provide new insights on the early antiviral response to VHSV in resistant and susceptible rainbow trout.

PubMed

Verrier, Eloi R; Genet, Carine; Laloë, Denis; Jaffrezic, Florence; Rau, Andrea; Esquerre, Diane; Dechamp, Nicolas; Ciobotaru, Céline; Hervet, Caroline; Krieg, Francine; Jouneau, Luc; Klopp, Christophe; Quillet, Edwige; Boudinot, Pierre

2018-06-19

The viral hemorrhagic septicemia virus (VHSV) is a major threat for salmonid farming and for wild fish populations worldwide. Previous studies have highlighted the importance of innate factors regulated by a major quantitative trait locus (QTL) for the natural resistance to waterborne VHSV infection in rainbow trout. The aim of this study was to analyze the early transcriptomic response to VHSV inoculation in cell lines derived from previously described resistant and susceptible homozygous isogenic lines of rainbow trout to obtain insights into the molecular mechanisms responsible for the resistance to the viral infection. We first confirmed the presence of the major QTL in a backcross involving a highly resistant fish isogenic line (B57) and a highly susceptible one (A22), and were able to define the confidence interval of the QTL and to identify its precise position. We extended the definition of the QTL since it controls not only resistance to waterborne infection but also the kinetics of mortality after intra-peritoneal injection. Deep sequencing of the transcriptome of B57 and A22 derived cell lines exposed to inactivated VHSV showed a stronger response to virus inoculation in the resistant background. In line with our previous observations, an early and strong induction of interferon and interferon-stimulated genes was correlated with the resistance to VHSV, highlighting the major role of innate immune factors in natural trout resistance to the virus. Interestingly, major factors of the antiviral innate immunity were much more expressed in naive B57 cells compared to naive A22 cells, which likely contributes to the ability of B57 to mount a fast antiviral response after viral infection. These observations were further extended by the identification of several innate immune-related genes localized close to the QTL area on the rainbow trout genome. Taken together, our results improve our knowledge in virus-host interactions in vertebrates and provide novel insights in the molecular mechanisms explaining the resistance to VHSV in rainbow trout. Our data also provide a collection of potential markers for resistance and susceptibility of rainbow trout to VHSV infection.

Reconstructing the past outburst history of Eta Carinae from WFPC2 proper motions

NASA Astrophysics Data System (ADS)

Smith, Nathan

2016-10-01

The HST archive contains multiple epochs of WFPC2 images of the nebula around Eta Carinae taken over a 15-year timespan, although only the earliest few years of data have been analyzed and published. The fact that all these images were taken with the same instrument, with the same pixel sampling and field distortion, makes them an invaluable resource for accurately measuring the expanding ejecta. The goal of a previously accepted AR proposal was to analyze the full set of appropriate continuum-filter HST images to place precise constraints on the avereage ejection date of the Homunculus Nebula; this analysis is now complete (Smith et al 2016) and the nebula appears to have been ejected in the second half of 1847. Here we propose to continue this project by constraining the motion of the more extended and much older Outer Ejecta around Eta Carinae. Older material outside the main bipolar nebula traces previous major outbursts of the star with no recorded historical observations. We propose an ambitious reduction and analysis of the complete WFPC2 imaging dataset of Eta Car. These data can reconstruct its violent mass-loss history over the past thousand years. We have already started this by analyzing two epochs of ACS F658N images, and astonishingly, these data suggested two previous eruptions in the 13th and 15th centuries assuming ballistic motion. WFPC2 images will extend the baseline by 10 yr, and critically, more than 2 epochs allow us to measure any deceleration in the ejecta. We will also analyze Doppler shifts in ground-based spectra in order to reconstruct the 3D geometry of past mass ejection. This AR proposal will fund the final year of a PhD thesis.

A selective sweep of >8 Mb on chromosome 26 in the Boxer genome.

PubMed

Quilez, Javier; Short, Andrea D; Martínez, Verónica; Kennedy, Lorna J; Ollier, William; Sanchez, Armand; Altet, Laura; Francino, Olga

2011-07-01

Modern dog breeds display traits that are either breed-specific or shared by a few breeds as a result of genetic bottlenecks during the breed creation process and artificial selection for breed standards. Selective sweeps in the genome result from strong selection and can be detected as a reduction or elimination of polymorphism in a given region of the genome. Extended regions of homozygosity, indicative of selective sweeps, were identified in a genome-wide scan dataset of 25 Boxers from the United Kingdom genotyped at ~20,000 single-nucleotide polymorphisms (SNPs). These regions were further examined in a second dataset of Boxers collected from a different geographical location and genotyped using higher density SNP arrays (~170,000 SNPs). A selective sweep previously associated with canine brachycephaly was detected on chromosome 1. A novel selective sweep of over 8 Mb was observed on chromosome 26 in Boxer and for a shorter region in English and French bulldogs. It was absent in 171 samples from eight other dog breeds and 7 Iberian wolf samples. A region of extended increased heterozygosity on chromosome 9 overlapped with a previously reported copy number variant (CNV) which was polymorphic in multiple dog breeds. A selective sweep of more than 8 Mb on chromosome 26 was identified in the Boxer genome. This sweep is likely caused by strong artificial selection for a trait of interest and could have inadvertently led to undesired health implications for this breed. Furthermore, we provide supporting evidence for two previously described regions: a selective sweep on chromosome 1 associated with canine brachycephaly and a CNV on chromosome 9 polymorphic in multiple dog breeds.

Payload specialist Reinhard Furrer show evidence of previous blood sampling

NASA Technical Reports Server (NTRS)

1985-01-01

Payload specialist Reinhard Furrer shows evidence of previous blood sampling while Wubbo J. Ockels, Dutch payload specialist (only partially visible), extends his right arm after a sample has been taken. Both men show bruises on their arms.

When Traits Match States: Examining the Associations between Self-Report Trait and State Mindfulness following a State Mindfulness Induction.

PubMed

Bravo, Adrian J; Pearson, Matthew R; Wilson, Adam D; Witkiewitz, Katie

2018-02-01

Previous research has found inconsistent relationships between trait mindfulness and state mindfulness. To extend previous research, we sought to examine the unique associations between self-report trait mindfulness and state mindfulness by levels of meditation experience (meditation-naïve vs. meditation-experienced) and by mindfulness induction (experimentally induced mindful state vs. control group). We recruited 299 college students (93 with previous mindfulness meditation experience) to participate in an experiment that involved the assessment of five facets of trait mindfulness (among other constructs), followed by a mindfulness induction (vs. control), followed by the assessment of state mindfulness of body and mind. Correlational analyses revealed limited associations between trait mindfulness facets and facets of state mindfulness, and demonstrated that a brief mindfulness exercise focused on bodily sensations and the breath elicited higher state mindfulness of body but not state mindfulness of mind. We found significant interactions such that individuals with previous meditation experience and higher scores on the observing facet of trait mindfulness had the highest levels of state mindfulness of body and mind. Among individuals with meditation experience, the strengths of the associations between observing trait mindfulness and the state mindfulness facets increased with frequency of meditation practice. Some other interactions ran counter to expectations. Overall, the relatively weak associations between trait and state mindfulness demonstrates the need to improve our operationalizations of mindfulness, advance our understanding of how to best cultivate mindfulness, and reappraise the ways in which mindfulness can manifest as a state and as a trait.

DETERMINING THE NATURE OF THE EXTENDED H I STRUCTURE AROUND LITTLE THINGS DWARF GALAXY NGC 1569

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Megan, E-mail: mjohnson@nrao.edu; National Radio Astronomy Observatory, P.O. Box 2, Green Bank, WV 24915

2013-06-15

This work presents an extended, neutral hydrogen emission map around Magellanic-type dwarf irregular galaxy (dIm) NGC 1569. In the spring of 2010, the Robert C. Byrd Green Bank Telescope was used to map a 9 Degree-Sign Multiplication-Sign 2 Degree-Sign region in H I line emission that includes NGC 1569 and IC 342 as well as two other dwarf galaxies. The primary objective for these observations was to search for structures potentially connecting NGC 1569 with IC 342 group members in order to trace previous interactions and thus, provide an explanation for the starburst and peculiar kinematics prevalent in NGC 1569.more » A large, half-degree diameter H I cloud was detected that shares the same position and velocity as NGC 1569. Also, two long structures were discovered that are reminiscent of intergalactic filaments extending out in a V-shaped manner from NGC 1569 toward UGCA 92, a nearby dwarf galaxy. These filamentary structures extend for about 1. Degree-Sign 5, which is 77 kpc at NGC 1569. There is a continuous velocity succession with the 0. Degree-Sign 5 H I cloud, filaments, and main body of the galaxy. The 0. Degree-Sign 5 H I cloud and filamentary structures may be foreground Milky Way, but are suggestive as possible remnants of an interaction between NGC 1569 and UGCA 92. The data also show two tidal tails extending from UGCA 86 and IC 342, respectively. These structures may be part of a continuous H I bridge but more data are needed to determine if this is the case.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beidler, M. T.; Cassak, P. A.; Jardin, S. C.

We diagnose local properties of magnetic reconnection during a sawtooth crash employing the three-dimensional toroidal, extended-magnetohydrodynamic (MHD) code M3D-C 1. To do so, we sample simulation data in the plane in which reconnection occurs, the plane perpendicular to the helical (m, n) = (1, 1) mode at the q = 1 surface, where m and n are the poloidal and toroidal mode numbers and q is the safety factor. We study the nonlinear evolution of a particular test equilibrium in a non-reduced field representation using both resistive-MHD and extended-MHD models. We find growth rates for the extended-MHD reconnection process exhibitmore » a nonlinear acceleration and greatly exceed that of the resistive-MHD model, as is expected from previous experimental, theoretical, and computational work. We compare the properties of reconnection in the two simulations, revealing the reconnecting current sheets are locally different in the two models and we present the first observation of the quadrupole out-of-plane Hall magnetic field that appears during extended-MHD reconnection in a 3D toroidal simulation (but not in resistive-MHD). We also explore the dependence on toroidal angle of the properties of reconnection as viewed in the plane perpendicular to the helical magnetic field, finding qualitative and quantitative effects due to changes in the symmetry of the reconnection process. Furthermore, this study is potentially important for a wide range of magnetically confined fusion applications, from confirming simulations with extended-MHD effects are sufficiently resolved to describe reconnection, to quantifying local reconnection rates for purposes of understanding and predicting transport, not only at the q = 1 rational surface for sawteeth, but also at higher order rational surfaces that play a role in disruptions and edge-confinement degradation.« less

Extended-range forecasting of Chinese summer surface air temperature and heat waves

NASA Astrophysics Data System (ADS)

Zhu, Zhiwei; Li, Tim

2018-03-01

Because of growing demand from agricultural planning, power management and activity scheduling, extended-range (5-30-day lead) forecasting of summer surface air temperature (SAT) and heat waves over China is carried out in the present study via spatial-temporal projection models (STPMs). Based on the training data during 1960-1999, the predictability sources are found to propagate from Europe, Northeast Asia, and the tropical Pacific, to influence the intraseasonal 10-80 day SAT over China. STPMs are therefore constructed using the projection domains, which are determined by these previous predictability sources. For the independent forecast period (2000-2013), the STPMs can reproduce EOF-filtered 30-80 day SAT at all lead times of 5-30 days over most part of China, and observed 30-80 and 10-80 day SAT at 25-30 days over eastern China. Significant pattern correlation coefficients account for more than 50% of total forecasts at all 5-30-day lead times against EOF-filtered and observed 30-80 day SAT, and at a 20-day lead time against observed 10-80 day SAT. The STPMs perform poorly in reproducing 10-30 day SAT. Forecasting for the first two modes of 10-30 day SAT only shows useful skill within a 15-day lead time. Forecasting for the third mode of 10-30 day SAT is useless after a 10-day lead time. The forecasted heat waves over China are determined by the reconstructed SAT which is the summation of the forecasted 10-80 day SAT and the lower frequency (longer than 80-day) climatological SAT. Over a large part of China, the STPMs can forecast more than 30% of heat waves within a 15-day lead time. In general, the STPMs demonstrate the promising skill for extended-range forecasting of Chinese summer SAT and heat waves.

Extending and Applying the EPIC Architecture for Human Cognition and Performance: Auditory and Spatial Components

DTIC Science & Technology

2013-03-20

Wakefield of the University of Michigan as Co-PI. This extended activity produced a large number of products and accomplishments; however, this report...speech communication will be expanded to provide a robust modeling and prediction capability for tasks involving speech production and speech and non...preparations made to move to the newer Cocoa API instead of the previous Carbon API. In the following sections, an extended treatment will be

Where Do I Start (Beginning the Investigation)?

NASA Astrophysics Data System (ADS)

Kornacki, Jeffrey L.

No doubt some will open directly to this chapter, because your product is contaminated with an undesirable microbe, or perhaps you have been asked to do such an investigation for another company's facility not previously observed by you and naturally you want tips on how to find where the contaminant is getting into the product stream. This chapter takes the reader through the process of beginning the investigation including understanding the process including the production schedule and critically reviewing previously generated laboratory data. Understanding the critical control points and validity of their critical limits is also important. Scoping the extent of the problem is next. It is always a good idea for the factory to have a rigorously validated cleaning and sanitation procedure that provides a documented "sanitation breakpoint," which can be useful in the "scoping" process, although some contamination events may extend past these "break-points." Touring the facility is next wherein preliminary pre-selection of areas for future sampling can be done. Operational samples and observations in non-food contact areas can be taken at this time. Then the operations personnel need to be consulted and plans made for an appropriate amount of time to observe equipment break down for "post-operational" sampling and "pre-operational" investigational sampling. Hence the chapter further discusses preparing operations personnel for the disruptions that go along with these investigations and assembling the sampling team. The chapter concludes with a discussion of post-startup observations after an investigation and sampling.

Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat.

PubMed

Melman, A; Biggs, G; Davies, K; Zhao, W; Tar, M T; Christ, G J

2008-03-01

Previous reports have demonstrated that gene transfer with the alpha, or pore-forming, subunit of the human Maxi-K channel (hSlo) restores the decline in erectile capacity observed in established rat models of diabetes and aging. Preliminary data from a human clinical trial also showed safety and potential efficacy in 11 men treated with the same plasmid construct expressing the Maxi-K channel. In all instances, the original plasmid was driven by the heterologous cytomegalovirus promoter which is broadly active in a wide variety of cell and tissue types. To more precisely determine the contribution of the corporal myocyte to the observed physiological effects in vivo, we report here our initial work using a distinct vector (pSMAA-hSlo) in which hSlo gene expression was driven off the mouse smooth muscle alpha-actin (SMAA) promoter. Specifically, older rats, with diminished erectile capacity, were given a single intracorporal injection with either 100 mug pVAX-hSlo or 10, 100 or 1000 mug pSMAA-hSlo, or vector or vehicle alone. Significantly increased intracavernous pressure (ICP) responses to cavernous nerve stimulation were observed for all doses of both plasmids encoding hSlo, relative to control injections. These data confirm and extend previous observations to document that smooth muscle cell-specific expression of hSlo in corporal tissue is both necessary and sufficient to restore erectile function in aging rats.

Enhanced thermoelectric properties of N-type polycrystalline In4Se3-x compounds via thermally induced Se deficiency

NASA Astrophysics Data System (ADS)

Zhao, Ran; Shu, Yu-Tian; Guo, Fu

2014-03-01

In4Se3-x compound is considered as a potential thermoelectric material due to its comparably low thermal conductivity among all existing ones. While most studies investigated In4Se3-x thermoelectric properties by controlling selennium or other dopants concentrations, in the current study, it was found that even for a fixed initial In/Se ratio, the resulting In/Se ratio varied significantly with different thermal processing histories (i.e., melting and annealing), which also resulted in varied thermoelectric properties as well as fracture surface morphologies of In4Se3-x polycrystalline specimens. Single phase polycrystalline In4Se3-x compounds were synthesized by combining a sequence of melting, annealing, pulverizing, and spark plasma sintering. The extension of previous thermal history was observed to significantly improve the electrical conductivity (about 121%) and figure of merit (about 53%) of In4Se3-x polycrystalline compounds. The extended thermal history resulted in the increase of Se deficiency (x) from 0.39 to 0.53. This thermally induced Se deficiency was observed to associate with increasing carrier mobility but decreasing concentration, which differs from the general trend observed for the initially adjusted Se deficiency at room temperature. Unusually large dispersed grains with nanosize layers were observed in specimens with the longest thermal history. The mechanism(s) by which previous thermal processing enhances carrier mobility and affect microstructural evolution are briefly discussed.

Long-term studies with the Ariel-5 asm. 1: Her X-1, Vela X-1 and Cen X-3. [periodic variations

NASA Technical Reports Server (NTRS)

Holt, S. S.; Kaluzienski, L. J.; Boldt, E. A.; Serlemitsos, P. J.

1978-01-01

Twelve hundred days of 3-6 keV X-ray data from Her X-1, Vela X-1 and Cen X-3 accumulated with the Ariel-5 all-sky monitor are interrogated. The binary periodicities of all three can be clearly observed, as can the approximately 35-d variation of Her X-1, for which we can refine the period to 34.875 plus or minus .030-d. No such longer-term periodicity less than 200-d is observed from Vela X-1. The 26.6-d low-state recurrence period for Cen X-3 previously suggested is not observed, but a 43.0-d candidate periodicity is found which may be consistent with the precession of an accretion disk in that system. The present results are illustrative of the long-term studies which can be performed on approximately 50 sources over a temporal base which will ultimately extend to at least 1800 days.

Use of Vertically Integrated Ice in WRF-Based Forecasts of Lightning Threat

NASA Technical Reports Server (NTRS)

McCaul, E. W., jr.; Goodman, S. J.

2008-01-01

Previously reported methods of forecasting lightning threat using fields of graupel flux from WRF simulations are extended to include the simulated field of vertically integrated ice within storms. Although the ice integral shows less temporal variability than graupel flux, it provides more areal coverage, and can thus be used to create a lightning forecast that better matches the areal coverage of the lightning threat found in observations of flash extent density. A blended lightning forecast threat can be constructed that retains much of the desirable temporal sensitivity of the graupel flux method, while also incorporating the coverage benefits of the ice integral method. The graupel flux and ice integral fields contributing to the blended forecast are calibrated against observed lightning flash origin density data, based on Lightning Mapping Array observations from a series of case studies chosen to cover a wide range of flash rate conditions. Linear curve fits that pass through the origin are found to be statistically robust for the calibration procedures.

Phonetic imitation by young children and its developmental changes.

PubMed

Nielsen, Kuniko

2014-12-01

In the current study, the author investigated the developmental course of phonetic imitation in childhood, and further evaluated existing accounts of phonetic imitation. Sixteen preschoolers, 15 third graders, and 18 college students participated in the current study. An experiment with a modified imitation paradigm with a picture-naming task was conducted, in which participants' voice-onset time (VOT) was compared before and after they were exposed to target speech with artificially increased VOT. Extended VOT in the target speech was imitated by preschoolers and 3rd graders as well as adults, confirming previous findings in phonetic imitation. Furthermore, an age effect of phonetic imitation was observed; namely, children showed greater imitation than adults, whereas the degree of imitation was comparable between preschoolers and 3rd graders. No significant effect of gender or word specificity was observed. Young children imitated fine phonetic details of the target speech, and greater degree of phonetic imitation was observed in children compared to adults. These findings suggest that the degree of phonetic imitation negatively correlates with phonological development.

Thermal and athermal three-dimensional swarms of self-propelled particles

NASA Astrophysics Data System (ADS)

Nguyen, Nguyen H. P.; Jankowski, Eric; Glotzer, Sharon C.

2012-07-01

Swarms of self-propelled particles exhibit complex behavior that can arise from simple models, with large changes in swarm behavior resulting from small changes in model parameters. We investigate the steady-state swarms formed by self-propelled Morse particles in three dimensions using molecular dynamics simulations optimized for graphics processing units. We find a variety of swarms of different overall shape assemble spontaneously and that for certain Morse potential parameters at most two competing structures are observed. We report a rich “phase diagram” of athermal swarm structures observed across a broad range of interaction parameters. Unlike the structures formed in equilibrium self-assembly, we find that the probability of forming a self-propelled swarm can be biased by the choice of initial conditions. We investigate how thermal noise influences swarm formation and demonstrate ways it can be exploited to reconfigure one swarm into another. Our findings validate and extend previous observations of self-propelled Morse swarms and highlight open questions for predictive theories of nonequilibrium self-assembly.

The occultation of Epsilon Geminorum by Mars - Analysis of McDonald data. [turbulent scintillation in light curves

NASA Technical Reports Server (NTRS)

Africano, J.; De Vaucouleurs, G.; Evans, D. S.; Finkel, B. E.; Nather, R. E.; Palm, C.; Silverberg, E.; Wiant, J.; Hubbard, W. B.; Jokipii, J. R.

1977-01-01

An analysis of observations of the occultation of Epsilon Gem by Mars on April 8, 1976, is presented. The data were obtained by three neighboring telescopes at McDonald Observatory. Intensity fluctuations on time scales of the order of 100 ms were observed simultaneously at the three telescopes. As the observations compare well with predictions of turbulent scintillation theory, it is concluded that such fluctuations were probably largely the effect of stellar scintillations in the Martian atmosphere. The stellar diameter is included as a parameter in the theory but in a way which differs from previously published interpretations of occultations of extended sources by planetary atmospheres. Scintillations govern the experimental uncertainty in the deduction of the scale height of the high Martian atmosphere. A density scale height of 9.9 + or - 2.5 km is obtained at an altitude of 74 + or - 8 km above the mean surface. For CO 2 gas, this result corresponds to a temperature of 190 + or - 50 K.

Understanding Others' Regret: A fMRI Study

PubMed Central

Canessa, Nicola; Motterlini, Matteo; Di Dio, Cinzia; Perani, Daniela; Scifo, Paola; Cappa, Stefano F.; Rizzolatti, Giacomo

2009-01-01

Previous studies showed that the understanding of others' basic emotional experiences is based on a “resonant” mechanism, i.e., on the reactivation, in the observer's brain, of the cerebral areas associated with those experiences. The present study aimed to investigate whether the same neural mechanism is activated both when experiencing and attending complex, cognitively-generated, emotions. A gambling task and functional-Magnetic-Resonance-Imaging (fMRI) were used to test this hypothesis using regret, the negative cognitively-based emotion resulting from an unfavorable counterfactual comparison between the outcomes of chosen and discarded options. Do the same brain structures that mediate the experience of regret become active in the observation of situations eliciting regret in another individual? Here we show that observing the regretful outcomes of someone else's choices activates the same regions that are activated during a first-person experience of regret, i.e. the ventromedial prefrontal cortex, anterior cingulate cortex and hippocampus. These results extend the possible role of a mirror-like mechanism beyond basic emotions. PMID:19826471

Wavelet transform analysis of the small-scale X-ray structure of the cluster Abell 1367

NASA Technical Reports Server (NTRS)

Grebeney, S. A.; Forman, W.; Jones, C.; Murray, S.

1995-01-01

We have developed a new technique based on a wavelet transform analysis to quantify the small-scale (less than a few arcminutes) X-ray structure of clusters of galaxies. We apply this technique to the ROSAT position sensitive proportional counter (PSPC) and Einstein high-resolution imager (HRI) images of the central region of the cluster Abell 1367 to detect sources embedded within the diffuse intracluster medium. In addition to detecting sources and determining their fluxes and positions, we show that the wavelet analysis allows a characterization of the sources extents. In particular, the wavelet scale at which a given source achieves a maximum signal-to-noise ratio in the wavelet images provides an estimate of the angular extent of the source. To account for the widely varying point response of the ROSAT PSPC as a function of off-axis angle requires a quantitative measurement of the source size and a comparison to a calibration derived from the analysis of a Deep Survey image. Therefore, we assume that each source could be described as an isotropic two-dimensional Gaussian and used the wavelet amplitudes, at different scales, to determine the equivalent Gaussian Full Width Half-Maximum (FWHM) (and its uncertainty) appropriate for each source. In our analysis of the ROSAT PSPC image, we detect 31 X-ray sources above the diffuse cluster emission (within a radius of 24 min), 16 of which are apparently associated with cluster galaxies and two with serendipitous, background quasars. We find that the angular extents of 11 sources exceed the nominal width of the PSPC point-spread function. Four of these extended sources were previously detected by Bechtold et al. (1983) as 1 sec scale features using the Einstein HRI. The same wavelet analysis technique was applied to the Einstein HRI image. We detect 28 sources in the HRI image, of which nine are extended. Eight of the extended sources correspond to sources previously detected by Bechtold et al. Overall, using both the PSPC and the HRI observations, we detect 16 extended features, of which nine have galaxies coincided with the X-ray-measured positions (within the positional error circles). These extended sources have luminosities lying in the range (3 - 30) x 10(exp 40) ergs/s and gas masses of approximately (1 - 30) x 10(exp 9) solar mass, if the X-rays are of thermal origin. We confirm the presence of extended features in A1367 first reported by Bechtold et al. (1983). The nature of these systems remains uncertain. The luminosities are large if the emission is attributed to single galaxies, and several of the extended features have no associated galaxy counterparts. The extended features may be associated with galaxy groups, as suggested by Canizares, Fabbiano, & Trinchieri (1987), although the number required is large.

Successful Graded Mirror Therapy in a Patient with Chronic Deafferentation Pain in Whom Traditional Mirror Therapy was Ineffective: A Case Report.

PubMed

Mibu, Akira; Nishigami, Tomohiko; Tanaka, Katsuyoshi; Osumi, Michihiro; Tanabe, Akihito

2016-04-01

A 43-year-old man had deafferentation pain in his right upper extremity secondary to brachial plexus avulsion from a traffic accident 23 years previously. On our initial examination, he had severe tingling pain with numbness in the right fingers rated 10 on the numerical rating scale. The body perception of the affected third and fourth fingers was distorted in the flexed position. Although he performed traditional mirror therapy (TMT) for 4 weeks in the same methods as seen in previous studies, he could not obtain willed motor imagery and pain-alleviation effect. Therefore, we modified the task of TMT: Graded mirror therapy (GMT). GMT consisted of five stages: (1) observation of the mirror reflection of the unaffected side without imagining any movements of the affected side; (2) observation of the mirror reflection of the third and fourth fingers changing shape gradually adjusted from a flexed position to a extended position; (3) observation of the mirror reflection of passive movement; (4) motor imagery of affected fingers with observation of the mirror reflection (similar to TMT); (5) motor imagery of affected fingers without mirror. Each task was performed for 3 to 4 weeks. As a result, pain intensity during mirror therapy gradually decreased and finally disappeared. The body perception of the affected fingers also improved, and he could imagine the movement of the fingers with or without mirror. We suggested that GMT starting from the observation task without motor imagery may effectively decrease deafferentation pain compared to TMT. © 2016 World Institute of Pain.

Observation of the Central Part of the Beta-Pictoris Disk with an Anti-Blooming CCD

NASA Astrophysics Data System (ADS)

Lecavelier Des Etangs, A.; Perrin, G.; Ferlet, R.; Vidal Madjar, A.; Colas, F.; Buil, C.; Sevre, F.; Arlot, J. E.; Beust, H.; Lagrange Henri, A. M.; Lecacheux, J.; Deleuil, M.; Gry, C.

1993-07-01

β Pictoris (A5V) possesses a circumstellar disk of gas and dust which is oriented edge-on to Earth. Possibly a planet may be indirectly responsible for spectroscopic events, presently interpreted as the signature of the vaporisation of comet-like bodies when grazing the star, and may have cleared up dust particles in the inner zone. Previous coronographic studies coupled with IRAS and ground based IR observations also seem to indicate that the inner regions of the disk may be possibly dust free. We have extended the coronographic studies closer to the star in order to directly observe this zone, through a different observational technique based on the use of an anti- blooming CCD. These new observations, recorded at La Silla (Chile), revealed the structure of the disk down to two arcsec from the star (30 AU from the star). A different nature of dust particles seems to be present in the inner regions of the disk, in possible relation with a planetary formation process. Also an inverted asymmetry is observed in the inner region of the disk when compared to the outer one, a structure possibly related to a non homogeneous distribution of the dust within the disk.

Land-cover observations as part of a Global Earth Observation System of Systems (GEOSS): Progress, activities, and prospects

USGS Publications Warehouse

Herold, M.; Woodcock, C.E.; Loveland, Thomas R.; Townshend, J.; Brady, M.; Steenmans, C.; Schmullius, C. C.

2008-01-01

The international land-cover community has been working with GEO since 2005 to build the foundations for land-cover observations as an integral part of a Global Earth Observation System of Systems (GEOSS). The Group on Earth Observation (GEO) has provided the platform to elevate the societal relevance of land cover monitoring and helped to link a diverse set of global, regional, and national activities. A dedicated 2007-2009 GEO work plan task has resulted in achievements on the strategic and implementation levels. Integrated Global Observations of the Land (IGOL), the land theme of the Integrated Global Observation Strategy (IGOS), has been approved and is now in the process of transition into GEO implementation. New global land-cover maps at moderate spatial resolutions (i.e., GLOBCOVER) are being produced using guidelines and standards of the international community. The Middecadal Global Landsat Survey for 2005-2006 is extending previous 1990 and 2000 efforts for global, high-quality Landsat data. Despite this progress, essential challenges for building a sustained global land-cover-observing system remain, including: international cooperation on the continuity of global observations; ensuring consistency in land monitoring approaches; community engagement and country participation in mapping activities; commitment to ongoing quality assurance and validation; and regional networking and capacity building.

Bolus Calculator Reduces Hypoglycemia in the Short Term and Fear of Hypoglycemia in the Long Term in Subjects with Type 1 Diabetes (CBMDI Study)

PubMed Central

Carreira, Mónica; Anarte, María Teresa; Linares, Francisca; Olveira, Gabriel; González Romero, Stella

2017-01-01

Abstract Background: In a previous study we demonstrated improvement in metabolic control and reduction in hypoglycemia in people with type 1 diabetes on multiple daily injections, after having used a bolus calculator for 4 months. Objective: To demonstrate whether (1) extending its use (2) or introducing it in the control group, previously subjected to treatment intensification, could further improve metabolic control and related psychological issues. Methods: After the previous clinical trial, in which the subjects were randomized either to treatment with the calculator or to control group for 4 months, both groups used the calculator during an additional 4-month period. Results: In the previous control group, after using the device, HbA1c did not improve (7.86% ± 0.87% vs. 8.01% ± 0.93%, P 0.215), although a significant decrease in postprandial hypoglycemia was observed (2.3 ± 2 vs. 1.1 ± 1.2/2 weeks, P 0.002). In the group in which the treatment was extended from 4 to 8 months, HbA1c did not improve either (7.61 ± 0.58 vs. 7.73 ± 0.65, P 0.209); however this group had a greater perceived treatment satisfaction (12.03 ± 4.26 vs. 13.71 ± 3.75, P 0.007) and a significant decrease in fear of hypoglycemia (28.24 ± 8.18 basal vs. 25.66 ± 8.02 at 8 months, P 0.026). Conclusions: The extension in the use of the calculator or its introduction in a previously intensified control group did not improve metabolic control, although it did confirm a decrease in hypoglycemic episodes in the short term, while the extension of its use to 8 months was associated with a reduction in fear of hypoglycemia and greater treatment satisfaction. PMID:28594575

The solidification of Al–Pd–Mn studied by high-energy X-ray diffraction from electrostatically levitated samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quirinale, Dante G.

Here, we report on the results of a high-energy x-ray diffraction study of Al–Pd–Mn to investigate the solidification products obtained during free-cooling using an electrostatic levitation furnace. The primary solidification product from the melt is i-Al–Pd–Mn which coexists with a significant remaining liquid component. As the sample cools further, we find that the solidification pathway is consistent with the liquidus projection and pseudo-binary cut through the ternary phase diagram reported previously. At ambient temperature we have identified the major phase to be the ξ'-phase orthorhombic approximant, along with minor phases identified as Al and, most likely, the R-phase orthorhombic approximant.more » We have also observed a distinct prepeak in the liquid at high temperature, signifying the presence of extended atomic order. Interestingly, this prepeak was not observed in previous neutron diffraction measurements on the Al–Pd–Mn system. No undercooling was observed preceding the solidification of the i-Al–Pd–Mn phase from the melt which may signal the close similarity of the short-range order in the solid and liquid. However, this can not be clearly determined because of the potential for heterogenous nucleation associated with the presence of an Al2O3 impurity at the surface of the sample.« less

Pre-accretional sorting of grains in the outer solar nebula

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wozniakiewicz, P. J.; Bradley, J. P.; Ishii, H. A.

2013-12-20

Despite their micrometer-scale dimensions and nanogram masses, chondritic porous interplanetary dust particles (CP IDPs) are an important class of extraterrestrial material since their properties are consistent with a cometary origin and they show no evidence of significant post-accretional parent body alteration. Consequently, they can provide information about grain accretion in the comet-forming region of the outer solar nebula. We have previously reported our comparative study of the sizes and size distributions of crystalline silicate and sulfide grains in CP IDPs, in which we found these components exhibit a size-density relationship consistent with having been sorted together prior to accretion. Heremore » we extend our data set and include GEMS (glass with embedded metal and sulfide), the most abundant amorphous silicate phase observed in CP IDPs. We find that while the silicate and sulfide sorting trend previously observed is maintained, the GEMS size data do not exhibit any clear relationship to these crystalline components. Therefore, GEMS do not appear to have been sorted with the silicate and sulfide crystals. The disparate sorting trends observed in GEMS and the crystalline grains in CP IDPs present an interesting challenge for modeling early transport and accretion processes. They may indicate that several sorting mechanisms operated on these CP IDP components, or alternatively, they may simply be a reflection of different source environments.« less

76 FR 79244 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... Change To Extend the Penny Pilot Program December 15, 2011. Pursuant to Section 19(b)(1) of the... a proposal for the BATS Options Market (``BATS Options'') to extend through June 30, 2012, the Penny Pilot Program (``Penny Pilot'') in options classes in certain issues (``Pilot Program'') previously...

Observations on the vegetation of northeastern Mato Grosso II. Forests and soils of the Rio Suiá--Missu area.

PubMed

Ratter, J A; Askew, G P; Montgomery, R F; Gifford, D R

1978-12-04

The vegetation of the well drained soils along the Suiá--Missu road in the Serra do Roncador region of NE Mato Grosso is Evergreen Seasonal forest of Amazonian type. The area lies close to the meeting place of the Amazonian forest (the hylaea) and the cerrado (savanna) formation of Central Brazil. The structure of the forest is simple: the canopy is at about 18--23 m, and is exceeded by a few scattered emergents; no recognizable strata can be distinguished among the understorey trees and the shrub and herb layers are sparse. Table 1 lists the most important species and gives information on stratification and general distribution. Most of the species appear to have a hylaean centre of distribution but extend into other vegetation types. The forest differs from related communities which lie closer to the cerrado/forest boundary in its greater height and luxuriance, the presence of additional tall tree species, and the great reduction in abundance of a cerrado floristic element. A survey on the Xavantina--São Felix road allowed us to extend previous observations on the distance to which the cerrado tree Pterodon pubescens extends into the forest. The results obtained indicate a considerable extension of forest into cerrado during the life of an individual tree. A characteristic low forest occurs in the flood plain of the Rio Suiá--Missu while Swampy Gallery forests occur on permanently waterlogged soils around the headwaters of streams. The well drained soils of the Suiá--Missu forest are very uniform, deep latosols (oxisols) of very dystrophic nature with pH (in water) between 4.0 and 5.0 (see table 2, p. 203).

Extended Heat Deposition in Hot Jupiters: Application to Ohmic Heating

NASA Astrophysics Data System (ADS)

Ginzburg, Sivan; Sari, Re'em

2016-03-01

The observed radii of many giant exoplanets in close orbits exceed theoretical predictions. One suggested origin for this discrepancy is heat deposited deep inside the atmospheres of these “hot Jupiters”. Here, we study extended power sources that distribute heat from the photosphere to the deep interior of the planet. Our analytical treatment is a generalization of a previous analysis of localized “point sources”. We model the deposition profile as a power law in the optical depth and find that planetary cooling and contraction halt when the internal luminosity (I.e., cooling rate) of the planet drops below the heat deposited in the planet’s convective region. A slowdown in the evolutionary cooling prior to equilibrium is possible only for sources that do not extend to the planet’s center. We estimate the ohmic dissipation resulting from the interaction between the atmospheric winds and the planet’s magnetic field, and apply our analytical model to ohmically heated planets. Our model can account for the observed radii of most inflated planets, which have equilibrium temperatures of ≈1500-2500 K and are inflated to a radius of ≈ 1.6{R}J. However, some extremely inflated planets remain unexplained by our model. We also argue that ohmically inflated planets have already reached their equilibrium phase, and no longer contract. Following Wu & Lithwick, who argued that ohmic heating could only suspend and not reverse contraction, we calculate the time it takes ohmic heating to re-inflate a cold planet to its equilibrium configuration. We find that while it is possible to re-inflate a cold planet, the re-inflation timescales are longer by a factor of ≈ 30 than the cooling time.

Stellar feedback as the origin of an extended molecular outflow in a starburst galaxy.

PubMed

Geach, J E; Hickox, R C; Diamond-Stanic, A M; Krips, M; Rudnick, G H; Tremonti, C A; Sell, P H; Coil, A L; Moustakas, J

2014-12-04

Recent observations have revealed that starburst galaxies can drive molecular gas outflows through stellar radiation pressure. Molecular gas is the phase of the interstellar medium from which stars form, so these outflows curtail stellar mass growth in galaxies. Previously known outflows, however, involve small fractions of the total molecular gas content and have typical scales of less than a kiloparsec. In at least some cases, input from active galactic nuclei is dynamically important, so pure stellar feedback (the momentum return into the interstellar medium) has been considered incapable of rapidly terminating star formation on galactic scales. Molecular gas has been detected outside the galactic plane of the archetypal starburst galaxy M82 (refs 4 and 5), but so far there has been no evidence that starbursts can propel substantial quantities of cold molecular gas to the same galactocentric radius (about 10 kiloparsecs) as the warmer gas that has been traced by metal ion absorbers in the circumgalactic medium. Here we report observations of molecular gas in a compact (effective radius 100 parsecs) massive starburst galaxy at redshift 0.7, which is known to drive a fast outflow of ionized gas. We find that 35 per cent of the total molecular gas extends approximately 10 kiloparsecs, and one-third of this extended gas has a velocity of up to 1,000 kilometres per second. The kinetic energy associated with this high-velocity component is consistent with the momentum flux available from stellar radiation pressure. This demonstrates that nuclear bursts of star formation are capable of ejecting large amounts of cold gas from the central regions of galaxies, thereby strongly affecting their evolution by truncating star formation and redistributing matter.

Saturn's Rings and Associated Ring Plasma Cavity: Evidence for Slow Ring Erosion

NASA Technical Reports Server (NTRS)

Farrell, W. M.; Kurth, W. S.; Gurnett, D. A.; Persoon, A. M.; MacDowall, R. J.

2017-01-01

We re-examine the radio and plasma wave observations obtained during the Cassini Saturn orbit insertion period, as the spacecraft flew over the northern ring surface into a radial distance of 1.3 Rs (over the C-ring). Voyager era studies suggest the rings are a source of micro-meteoroid generated plasma and dust, with theorized peak impact-created plasma outflows over the densest portion of the rings (central B-ring). In sharp contrast, the Cassini Radio and Plasma Wave System (RPWS) observations identify the presence of a ring-plasma cavity located in the central portion of the B-ring, with little evidence of impact-related plasma. While previous Voyager era studies have predicted unstable ion orbits over the C- ring, leading to field-aligned plasma transport to Saturns ionosphere, the Cassini RPWS observations do not reveal evidence for such instability-created plasma fountains. Given the passive ring loss processes observed by Cassini, we find that the ring lifetimes should extend >10(exp 9) years, and that there is limited evidence for prompt destruction (loss in <100 Myrs).

An XMM-Newton Observation of the Seyfert Galaxy 1H0419-577 in an Extreme Low State

NASA Technical Reports Server (NTRS)

Pounds, K. A.; Reeves, J. N.; Page, K. L.; O'Brien, P. T.

2003-01-01

Previous observations of the luminous Seyfert galaxy 1H 0419-577 have found its X-ray spectrum to range from that of a typical Seyfert 1 with 2-10 keV power law index Gamma approx. 1.9 to a much flatter power law of Gamma approx. 1.5 or less. We report here a new XMM-Newton observation which allows the low state spectrum to be studied in much greater detail than hitherto. We find a very hard spectrum (Gamma approx. 1.0) which exhibits broad features that can be modelled with the addition of an extreme relativistic Fe K emission line or with partial covering of the underlying continuum by a substantial column density of near-neutral gas. Both the EPIC and RGS data show evidence for strong line emission of OVII and OVIII requiring an extended region of low density photoionised gas in 1H 0419- 577. Comparison with an earlier XMM-Newton observation when 1H 0419-577 was X-ray bright indicates the dominant spectral variability occurs via a steep power law component.

Fundamental Physics from Observations of White Dwarf Stars

NASA Astrophysics Data System (ADS)

Bainbridge, M. B.; Barstow, M. A.; Reindl, N.; Barrow, J. D.; Webb, J. K.; Hu, J.; Preval, S. P.; Holberg, J. B.; Nave, G.; Tchang-Brillet, L.; Ayres, T. R.

2017-03-01

Variation in fundamental constants provide an important test of theories of grand unification. Potentially, white dwarf spectra allow us to directly observe variation in fundamental constants at locations of high gravitational potential. We study hot, metal polluted white dwarf stars, combining far-UV spectroscopic observations, atomic physics, atmospheric modelling and fundamental physics, in the search for variation in the fine structure constant. This registers as small but measurable shifts in the observed wavelengths of highly ionized Fe and Ni lines when compared to laboratory wavelengths. Measurements of these shifts were performed by Berengut et al (2013) using high-resolution STIS spectra of G191-B2B, demonstrating the validity of the method. We have extended this work by; (a) using new (high precision) laboratory wavelengths, (b) refining the analysis methodology (incorporating robust techniques from previous studies towards quasars), and (c) enlarging the sample of white dwarf spectra. A successful detection would be the first direct measurement of a gravitational field effect on a bare constant of nature. We describe our approach and present preliminary results.

Saturn's rings and associated ring plasma cavity: Evidence for slow ring erosion

NASA Astrophysics Data System (ADS)

Farrell, W. M.; Kurth, W. S.; Gurnett, D. A.; Persoon, A. M.; MacDowall, R. J.

2017-08-01

We re-examine the radio and plasma wave observations obtained during the Cassini Saturn orbit insertion period, as the spacecraft flew over the northern ring surface into a radial distance of 1.3 Rs (over the C-ring). Voyager era studies suggest the rings are a source of micro-meteoroid generated plasma and dust, with theorized peak impact-created plasma outflows over the densest portion of the rings (central B-ring). In sharp contrast, the Cassini Radio and Plasma Wave System (RPWS) observations identify the presence of a ring-plasma cavity located in the central portion of the B-ring, with little evidence of impact-related plasma. While previous Voyager era studies have predicted unstable ion orbits over the C-ring, leading to field-aligned plasma transport to Saturn's ionosphere, the Cassini RPWS observations do not reveal evidence for such instability-created plasma 'fountains'. Given the passive ring loss processes observed by Cassini, we find that the ring lifetimes should extend >109 years, and that there is limited evidence for prompt destruction (loss in <100 Myrs).

An XMM-Newton Observation of the Seyfert 1 Galaxy 1H 0419-577 in an Extreme Low State

NASA Technical Reports Server (NTRS)

Pounds, K. A.; Reeves, J. N.; Page, K. L.; OBrien, P. T.

2004-01-01

Previous observations of the luminous Seyfert 1 galaxy 1H 0419-577 have found its X-ray spectrum to range from that of a typical Seyfert 1 with 2-10 keV power law index Gamma approx. 1.9 to a much flatter power law of Gamma approx. 1.5 or less. We report here a new XMM-Newton observation which allows the low state spectrum to be studied in much greater detail than hitherto. We find a very hard spectrum (Gamma approx. 1.0), which exhibits broad features that can be modelled myth the addition of an extreme relativistic Fe K emission line or with partial covering of the underlying continuum by a substantial column density of near-neutral gas. Both the EPIC and RGS data show evidence for strong line emission of OVII and OVIII requiring an extended region of low density photoionised gas in 1H 0419-577. Comparison with an earlier XMM-Newton observation when 1H 0419-577 was 'X-ray bright' indicates the dominant spectral variability occurs via a steep power law component.

SOLIS IV. Hydrocarbons in the OMC-2 FIR4 Region, a Probe of Energetic Particle Irradiation of the Region

NASA Astrophysics Data System (ADS)

Favre, C.; Ceccarelli, C.; López-Sepulcre, A.; Fontani, F.; Neri, R.; Manigand, S.; Kama, M.; Caselli, P.; Jaber Al-Edhari, A.; Kahane, C.; Alves, F.; Balucani, N.; Bianchi, E.; Caux, E.; Codella, C.; Dulieu, F.; Pineda, J. E.; Sims, I. R.; Theulé, P.

2018-06-01

We report new interferometric images of cyclopropenylidene, c-C3H2, toward the young protocluster OMC-2 FIR 4. The observations were performed at 82 and 85 GHz with the NOrthern Extended Millimeter Array (NOEMA) as part of the project Seeds Of Life In Space (SOLIS). In addition, IRAM-30 m data observations were used to investigate the physical structure of OMC-2 FIR 4. We find that the c-C3H2 gas emits from the same region where previous SOLIS observations showed bright HC5N emission. From a non-LTE analysis of the IRAM-30 m data, the c-C3H2 gas has an average temperature of ∼40 K, a H2 density of ∼3 × 105 cm‑3, and a c-C3H2 abundance relative to H2 of (7 ± 1) × 10‑12. In addition, the NOEMA observations provide no sign of significant c-C3H2 excitation temperature gradients across the region (about 3–4 beams), with T ex in the range 8 ± 3 up to 16 ± 7 K. We thus infer that our observations are inconsistent with a physical interaction of the OMC-2 FIR 4 envelope with the outflow arising from OMC-2 FIR 3, as claimed by previous studies. The comparison of the measured c-C3H2 abundance with the predictions from an astrochemical PDR model indicates that OMC-2 FIR 4 is irradiated by an FUV field ∼1000 times larger than the interstellar one, and by a flux of ionizing particles ∼4000 times larger than the canonical value of 1 × 10‑17 s‑1 from the Galaxy cosmic rays, which is consistent with our previous HC5N observations. This provides an important and independent confirmation of other studies that one, or more, source inside the OMC-2 FIR 4 region emits energetic (≥10 MeV) particles. Based on observations carried out under project number L15AA with the IRAM NOEMA Interferometer. IRAM is supported by INSU/CNRS (France), MPG (Germany) and IGN (Spain).

An Empirical Determination of the Intergalactic Background Light Using Near-Infrared Deep Galaxy Survey Data Out to 5 Micrometers and the Gamma-Ray Opacity of the Universe

NASA Technical Reports Server (NTRS)

Scully, Sean T.; Malkan, Matthew A.; Stecker, Floyd W.

2014-01-01

We extend our previous model-independent determination of the intergalactic background light, based purely on galaxy survey data, out to a wavelength of 5 micrometers. Our approach enables us to constrain the range of photon densities, based on the uncertainties from observationally determined luminosity densities and colors. We further determine a 68% confidence upper and lower limit on the opacity of the universe to gamma-rays up to energies of 1.6/(1 + z) terraelectron volts. A comparison of our lower limit redshift-dependent opacity curves to the opacity limits derived from the results of both ground-based air Cerenkov telescope and Fermi-LAT observations of PKS 1424+240 allows us to place a new upper limit on the redshift of this source, independent of IBL modeling.

SETI - The search for extraterrestrial intelligence - Plans and rationale

NASA Technical Reports Server (NTRS)

Wolfe, J. H.; Billingham, J.; Edelson, R. E.; Crow, R. B.; Gulkis, S.; Olsen, E. T.; Oliver, B. M.; Peterson, A. M.

1981-01-01

The methodology and instrumentation of a 10 yr search for extraterrestrial intelligence (SETI) program by NASA, comprising 5 yr for instrumentation development and 5 yr for observations, is described. A full sky survey in two polarizations between 1.2 and 10 GHz with resolution binwidths down to 32 Hz, and a two polarization can between 1.2-3 GHz with resolution binwidths down to 1 Hz of 700 nearby solar type stars within 20 light years of earth will extend the sensitivity of previous surveys by 300 times and cover 20,000 times more frequency space. EM signals are perceived as the only means for detecting life outside the solar system, and the SETI effort is driven by the empirical experience that once a physical process has been observed to occur, its occurrence elsewhere is assured. Further discussion is given of the history of searches for life in the Universe, the SETI search strategy, instrumentation, and signal identification.

Lifetime measurements in N=Z 72Kr

NASA Astrophysics Data System (ADS)

Andreoiu, C.; Svensson, C. E.; Austin, R. A. E.; Carpenter, M. P.; Dashdorj, D.; Finlay, P.; Freeman, S. J.; Garrett, P. E.; Görgen, A.; Greene, J.; Grinyer, G. F.; Hyland, B.; Jenkins, D.; Johnston-Theasby, F.; Joshi, P.; Machiavelli, A. O.; Moore, F.; Mukherjee, G.; Phillips, A. A.; Reviol, W.; Sarantites, D. G.; Schumaker, M. A.; Seweryniak, D.; Smith, M. B.; Valiente-Dobón, J. J.; Wadsworth, R.

2006-07-01

High-spin states in the N=Z nucleus 72Kr have been populated in the 40Ca(40Ca, 2α)72Kr fusion-evaporation reaction at a beam energy of 165 MeV and using a thin isotopically enriched 40Ca target. The experiment, performed at Argonne National Laboratory close to Chicago, USA, employed the Gammasphere array for γ-ray detection coupled to the Microball array for charged particle detection. The previously observed bands in 72Kr were extended to a higher excitation energy of ~24 MeV and higher angular momentum of 30planck. Using the Doppler-shift attenuation method, the lifetimes of high-spin states were measured for the first time in order to investigate deformation changes associated with the g9/2 proton and neutron alignments in this N=Z nucleus. An excellent agreement with theoretical calculations including only standard t=1 np pairing was observed.

IRAS observations of R Coronae Borealis - Detection and study of a fossil shell

NASA Technical Reports Server (NTRS)

Gillett, F. C.; Backman, D. E.; Beichman, C.; Neugebauer, G.

1986-01-01

IRAS observations of the extreme hydrogen-deficient supergiant R CrB are presented and discussed. The star is surrounded by an enormous cool dust cloud which is tentatively identified as a fossil remnant of the hydrogen-rich envelope of the star. The angular extent of the emission corresponds to a linear extent of 8 pc, 20 times larger than the largest previously known shell around a late-type star. The radiating material is distributed very symmetrically over a wide range of radial distances from the star. The dust temperature is nearly constant throughout the extended shell. The total mass in the shell is about 0.3 solar mass. The ejection process appears to have occurred in a spherically symmetric fashion with a nearly constant mass loss rate and expansion velocity over a period of about 150,000 yr, terminating about 26,000 yr ago.

A high resolution study of the glycocalyx of rat uterine epithelial cells during early pregnancy with the field emission gun scanning electron microscope.

PubMed Central

Jones, B J; Murphy, C R

1994-01-01

The field emission gun scanning electron microscope has been used to investigate morphological changes at the macromolecular level in the glycocalyx of rat uterine luminal epithelial cells during early pregnancy. This very high resolution microscope has allowed visualisation at a level previously unobtainable and has enabled us to establish that dramatic alterations occur in this glycocalyx at the time of blastocyst attachment. On d 1 of pregnancy a prominent, filamentous glycocalyx radiates from the microvilli. However, by d 6 of pregnancy when the microvilli have been replaced by irregular cell surface protrusions, the glycocalyceal filaments are completely lost and the plasma membrane appears smooth and covered with a felt-like coating. These morphological observations suggest a major reorganisation in surface carbohydrates during early pregnancy and extend histochemical observations on the uterine epithelial glycocalyx. Images Fig. 1 Fig. 2 Figs. 3 and 4 PMID:7961152

An empirical determination of the intergalactic background light using near-infrared deep galaxy survey data out to 5 μm and the gamma-ray opacity of the universe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scully, Sean T.; Malkan, Matthew A.; Stecker, Floyd W., E-mail: Floyd.W.Stecker@nasa.gov

2014-04-01

We extend our previous model-independent determination of the intergalactic background light, based purely on galaxy survey data, out to a wavelength of 5 μm. Our approach enables us to constrain the range of photon densities, based on the uncertainties from observationally determined luminosity densities and colors. We further determine a 68% confidence upper and lower limit on the opacity of the universe to γ-rays up to energies of 1.6/(1 + z) TeV. A comparison of our lower limit redshift-dependent opacity curves to the opacity limits derived from the results of both ground-based air Cerenkov telescope and Fermi-LAT observations of PKSmore » 1424+240 allows us to place a new upper limit on the redshift of this source, independent of IBL modeling.« less

Estimation of descriptive statistics for multiply censored water quality data

USGS Publications Warehouse

Helsel, Dennis R.; Cohn, Timothy A.

1988-01-01

This paper extends the work of Gilliom and Helsel (1986) on procedures for estimating descriptive statistics of water quality data that contain “less than” observations. Previously, procedures were evaluated when only one detection limit was present. Here we investigate the performance of estimators for data that have multiple detection limits. Probability plotting and maximum likelihood methods perform substantially better than simple substitution procedures now commonly in use. Therefore simple substitution procedures (e.g., substitution of the detection limit) should be avoided. Probability plotting methods are more robust than maximum likelihood methods to misspecification of the parent distribution and their use should be encouraged in the typical situation where the parent distribution is unknown. When utilized correctly, less than values frequently contain nearly as much information for estimating population moments and quantiles as would the same observations had the detection limit been below them.

Ozone depleting substances: a key forcing of the Brewer-Dobson circulation

NASA Astrophysics Data System (ADS)

Abalos, M.; Polvani, L. M.; Garcia, R. R.; Kinnison, D. E.; Randel, W. J.

2017-12-01

In contrast with monotonically-increasing greenhouse gases (GHG), Ozone Depleting Substances (ODS) peak approximately on the year 2000 and decrease thereafter, thanks to the Montreal Protocol. We examine the influence of these anthropogenic emissions on the Brewer-Dobson circulation (BDC) using specifically designed runs of the Community Earth System Model - Whole Atmosphere Community Climate Model (CESM-WACCM). Consistent with previous works, we find a dominant role of ODSs on the observed BDC acceleration up to 2000 in the SH summer, through dynamical changes induced by the ozone hole. We extend the analyses to quantify the influence of ODSs on the BDC for different regions and seasons, and compare the model results to observational estimates. Finally, we show that ODSs will substantially reduce the GHG-induced BDC acceleration in the future. Specifically, the trends in stratospheric mean age of air will be 4 times smaller in the period 2000-2080 as compared to the period 1965-2000.

A Supramolecular Ice Growth Inhibitor.

PubMed

Drori, Ran; Li, Chao; Hu, Chunhua; Raiteri, Paolo; Rohl, Andrew L; Ward, Michael D; Kahr, Bart

2016-10-12

Safranine O, a synthetic dye, was found to inhibit growth of ice at millimolar concentrations with an activity comparable to that of highly evolved antifreeze glycoproteins. Safranine inhibits growth of ice crystals along the crystallographic a-axis, resulting in bipyramidal needles extended along the <0001> directions as well as and plane-specific thermal hysteresis (TH) activity. The interaction of safranine with ice is reversible, distinct from the previously reported behavior of antifreeze proteins. Spectroscopy and molecular dynamics indicate that safranine forms aggregates in aqueous solution at micromolar concentrations. Metadynamics simulations and aggregation theory suggested that as many as 30 safranine molecules were preorganized in stacks at the concentrations where ice growth inhibition was observed. The simulations and single-crystal X-ray structure of safranine revealed regularly spaced amino and methyl substituents in the aggregates, akin to the ice-binding site of antifreeze proteins. Collectively, these observations suggest an unusual link between supramolecular assemblies of small molecules and functional proteins.

Searching for γ-ray emission from Reticulum II by Fermi-LAT

NASA Astrophysics Data System (ADS)

Zhao, Yi; Bi, Xiao-Jun; Yin, Peng-Fei; Zhang, Xinmin

2018-02-01

Recently, many new dwarf spheroidal satellites (dSphs) have been discovered by the Dark Energy Survey (DES). These dSphs are ideal candidates for probing for gamma-ray emissions from dark matter (DM) annihilation. However, no significant signature has been found by the Fermi-LAT dSph observations. In this work, we reanalyze the Fermi-LAT Pass 8 data from the direction of Reticulum II, where a slight excess has been reported by some previous studies. We treat Reticulum II (DES J0335.6-5403) as a spatially extended source, and find that no significant gamma-ray signature is observed. Based on this result, we set upper-limits on the DM annihilation cross section. Supported by National Natural Science Foundation of China (11121092, 11033005, 11375202, 11475191, 11475189), the CAS pilot B program (XDB23020000) and the National Key Program for Research and Development (2016YFA0400200)

Continuous quantum measurement and the quantum to classical transition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharya, Tanmoy; Habib, Salman; Jacobs, Kurt

2003-04-01

While ultimately they are described by quantum mechanics, macroscopic mechanical systems are nevertheless observed to follow the trajectories predicted by classical mechanics. Hence, in the regime defining macroscopic physics, the trajectories of the correct classical motion must emerge from quantum mechanics, a process referred to as the quantum to classical transition. Extending previous work [Bhattacharya, Habib, and Jacobs, Phys. Rev. Lett. 85, 4852 (2000)], here we elucidate this transition in some detail, showing that once the measurement processes that affect all macroscopic systems are taken into account, quantum mechanics indeed predicts the emergence of classical motion. We derive inequalities thatmore » describe the parameter regime in which classical motion is obtained, and provide numerical examples. We also demonstrate two further important properties of the classical limit: first, that multiple observers all agree on the motion of an object, and second, that classical statistical inference may be used to correctly track the classical motion.« less

Facial asymmetry as an indicator of psychological, emotional, and physiological distress.

PubMed

Shackelford, T K; Larsen, R J

1997-02-01

Fluctuating asymmetry (FA) is deviation from bilateral symmetry in morphological traits with asymmetry values that are normally distributed with a mean of 0. FA is produced by genetic or environmental perturbations of developmental design and may play a role in human sexual selection. K. Grammer and R. Thornhill (1994) found that facial FA negatively covaries with observer ratings of attractiveness, dominance, sexiness, and health. Using self-reports, observer ratings, daily diary reports, and psychophysiological measures, the authors assessed the relationship between facial FA and health in 2 samples of undergraduates (N = 101). Results partially replicate and extend those of K. Grammer and R. Thornhill (1994) and suggest that facial FA may signal psychological, emotional, and physiological distress. Discussion integrates the authors' findings with previous research on FA and suggests future research needed to clarify the role of FA in human sexual selection.

Production of edible carbohydrates from formaldehyde in a spacecraft. pH variations in the calcium hydroxide catalyzed formose reaction. Final Report, 1 Jul. 1973 - 30 Jun. 1974. M.S. Thesis

NASA Technical Reports Server (NTRS)

Weiss, A. H.; Kohler, J. T.; John, T.

1974-01-01

The study of the calcium hydroxide catalyzed condensation of formaldehyde was extended to a batch reactor system. Decreases in pH were observed, often in the acid regime, when using this basic catalyst. This observation was shown to be similar to results obtained by others using less basic catalysts in the batch mode. The relative rates of these reactions are different in a batch reactor than in a continuous stirred tank reactor. This difference in relative rates is due to the fact that at any degree of advancement in the batch system, the products have a history of previous products, pH, and dissolved catalyst. The relative rate differences can be expected to yield a different nature of product sugars for the two types of reactors.

Functional role of EMMPRIN in the formation and mineralisation of dental matrix in mouse molars.

PubMed

Xie, Ming; Xing, Guofang; Hou, Liwen; Bao, Jing; Chen, Yuqing; Jiao, Ting; Zhang, Fuqiang

2015-02-01

Our previous research has shown that the extracellular matrix metalloproteinase inducer (EMMPRIN) is expressed during and may function in the early development of tooth germs. In the present study, we observed the specific expression of EMMPRIN in ameloblasts and odontoblasts during the middle and late stages of tooth germ development using immunohistochemistry. Furthermore, to extend our understanding of the function of EMMPRIN in odontogenesis, we used an anti-EMMPRIN function-blocking antibody to remove EMMPRIN activity in tooth germ culture in vitro. Both the formation and mineralisation of dental hard tissues were suppressed in the tooth germ culture after the abrogation of EMMPRIN. Meanwhile, significant reductions in VEGF, MMP-9, ALPL, ameloblastin, amelogenin and enamelin expression were observed in antibody-treated tooth germ explants compared to control and normal serum-treated explants. The current results illustrate that EMMPRIN may play a critical role in the processing and maturation of the dental matrix.

Ranging algebraically with more observations than unknowns

NASA Astrophysics Data System (ADS)

Awange, J. L.; Fukuda, Y.; Takemoto, S.; Ateya, I. L.; Grafarend, E. W.

2003-07-01

In the recently developed Spatial Reference System that is designed to check and control the accuracy of the three-dimensional coordinate measuring machines and tooling equipment (Metronom US., Inc., Ann Arbor: http://www.metronomus.com), the coordinates of the edges of the instrument are computed from distances of the bars. The use of distances in industrial application is fast gaining momentum just as in Geodesy and in Geophysical applications and thus necessitating efficient algorithms to solve the nonlinear distance equations. Whereas the ranging problem with minimum known stations was considered in our previous contribution in the same Journal, the present contribution extends to the case where one is faced with many distance observations than unknowns (overdetermined case) as is usually the case in practise. Using the Gauss-Jacobi Combinatorial approach, we demonstrate how one can proceed to position without reverting to iterative and linearizing procedures such as Newton's or Least Squares approach.

Modeling false positive detections in species occurrence data under different study designs.

PubMed

Chambert, Thierry; Miller, David A W; Nichols, James D

2015-02-01

The occurrence of false positive detections in presence-absence data, even when they occur infrequently, can lead to severe bias when estimating species occupancy patterns. Building upon previous efforts to account for this source of observational error, we established a general framework to model false positives in occupancy studies and extend existing modeling approaches to encompass a broader range of sampling designs. Specifically, we identified three common sampling designs that are likely to cover most scenarios encountered by researchers. The different designs all included ambiguous detections, as well as some known-truth data, but their modeling differed in the level of the model hierarchy at which the known-truth information was incorporated (site level or observation level). For each model, we provide the likelihood, as well as R and BUGS code needed for implementation. We also establish a clear terminology and provide guidance to help choosing the most appropriate design and modeling approach.

Fermi-LAT Gamma-Ray Detections of Classical Novae V1369 Centauri 2013 and V5668 Sagittarii 2015

NASA Astrophysics Data System (ADS)

Cheung, C. C.; Jean, P.; Shore, S. N.; Stawarz, Ł.; Corbet, R. H. D.; Knödlseder, J.; Starrfield, S.; Wood, D. L.; Desiante, R.; Longo, F.; Pivato, G.; Wood, K. S.

2016-08-01

We report the Fermi Large Area Telescope (LAT) detections of high-energy (>100 MeV) γ-ray emission from two recent optically bright classical novae, V1369 Centauri 2013 and V5668 Sagittarii 2015. At early times, Fermi target-of-opportunity observations prompted by their optical discoveries provided enhanced LAT exposure that enabled the detections of γ-ray onsets beginning ˜2 days after their first optical peaks. Significant γ-ray emission was found extending to 39-55 days after their initial LAT detections, with systematically fainter and longer-duration emission compared to previous γ-ray-detected classical novae. These novae were distinguished by multiple bright optical peaks that encompassed the time spans of the observed γ-rays. The γ-ray light curves and spectra of the two novae are presented along with representative hadronic and leptonic models, and comparisons with other novae detected by the LAT are discussed.

Multi-band, multi-epoch observations of the transiting warm Jupiter WASP-80b

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukui, Akihiko; Kuroda, Daisuke; Kawashima, Yui

WASP-80b is a warm Jupiter transiting a bright late-K/early-M dwarf, providing a good opportunity to extend the atmospheric study of hot Jupiters toward the lower temperature regime. We report multi-band, multi-epoch transit observations of WASP-80b by using three ground-based telescopes covering from optical (g', R{sub c}, and I{sub c} bands) to near-infrared (NIR; J, H, and K{sub s} bands) wavelengths. We observe 5 primary transits, each in 3 or 4 different bands simultaneously, obtaining 17 independent transit light curves. Combining them with results from previous works, we find that the observed transmission spectrum is largely consistent with both a solarmore » abundance and thick cloud atmospheric models at a 1.7σ discrepancy level. On the other hand, we find a marginal spectral rise in the optical region compared to the NIR region at the 2.9σ level, which possibly indicates the existence of haze in the atmosphere. We simulate theoretical transmission spectra for a solar abundance but hazy atmosphere, finding that a model with equilibrium temperature of 600 K can explain the observed data well, having a discrepancy level of 1.0σ. We also search for transit timing variations, but find no timing excess larger than 50 s from a linear ephemeris. In addition, we conduct 43 day long photometric monitoring of the host star in the optical bands, finding no significant variation in the stellar brightness. Combined with the fact that no spot-crossing event is observed in the five transits, our results confirm previous findings that the host star appears quiet for spot activities, despite the indications of strong chromospheric activities.« less

Examining the Effect of Age on Visual-Vestibular Self-Motion Perception Using a Driving Paradigm.

PubMed

Ramkhalawansingh, Robert; Keshavarz, Behrang; Haycock, Bruce; Shahab, Saba; Campos, Jennifer L

2017-05-01

Previous psychophysical research has examined how younger adults and non-human primates integrate visual and vestibular cues to perceive self-motion. However, there is much to be learned about how multisensory self-motion perception changes with age, and how these changes affect performance on everyday tasks involving self-motion. Evidence suggests that older adults display heightened multisensory integration compared with younger adults; however, few previous studies have examined this for visual-vestibular integration. To explore age differences in the way that visual and vestibular cues contribute to self-motion perception, we had younger and older participants complete a basic driving task containing visual and vestibular cues. We compared their performance against a previously established control group that experienced visual cues alone. Performance measures included speed, speed variability, and lateral position. Vestibular inputs resulted in more precise speed control among older adults, but not younger adults, when traversing curves. Older adults demonstrated more variability in lateral position when vestibular inputs were available versus when they were absent. These observations align with previous evidence of age-related differences in multisensory integration and demonstrate that they may extend to visual-vestibular integration. These findings may have implications for vehicle and simulator design when considering older users.

Classical conditioning of proboscis extension in harnessed Africanized honey bee queens (Apis mellifera L.).

PubMed

Aquino, Italo S; Abramson, Charles I; Soares, Ademilson E E; Fernandes, Andrea Cardoso; Benbassat, Danny

2004-06-01

Experiments are reported on learning in virgin Africanized honey bee queens (Apis mellifera L.). Queens restrained in a "Pavlovian harness" received a pairing of hexanal odor with a 1.8-M feeding of sucrose solution. Compared to explicitly unpaired controls, acquisition was rapid in reaching about 90%. Acquisition was also rapid in queens receiving an unconditioned stimulus of "bee candy" or an unconditioned stimulus administered by worker bees. During extinction the conditioned response declines. The steepest decline was observed in queens receiving an unconditioned stimulus of bee candy. These findings extend previous work on learning of Afrianized honey bee workers to a population of queen bees.

Fixed interval smoothing with discrete measurements.

NASA Technical Reports Server (NTRS)

Bierman, G. J.

1972-01-01

Smoothing equations for a linear continuous dynamic system with linear discrete measurements, derived from the discrete results of Rauch, Tung, and Striebel (1965), (R-T-S), are used to extend, through recursive updating, the previously published results of Bryson and Frazier (1963), (B-F), and yield a modified Bryson and Frazier, (M-B-F), algorithm. A comparison of the (M-B-F) and (R-T-S) algorithms leads to the conclusion that the former is to be preferred because it entails less computation, less storage, and less instability. It is felt that the presented (M-B-F) smoothing algorithm is a practical mechanization and should be of value in smoothing discretely observed dynamic linear systems.

Locally-Based Kernal PLS Smoothing to Non-Parametric Regression Curve Fitting

NASA Technical Reports Server (NTRS)

Rosipal, Roman; Trejo, Leonard J.; Wheeler, Kevin; Korsmeyer, David (Technical Monitor)

2002-01-01

We present a novel smoothing approach to non-parametric regression curve fitting. This is based on kernel partial least squares (PLS) regression in reproducing kernel Hilbert space. It is our concern to apply the methodology for smoothing experimental data where some level of knowledge about the approximate shape, local inhomogeneities or points where the desired function changes its curvature is known a priori or can be derived based on the observed noisy data. We propose locally-based kernel PLS regression that extends the previous kernel PLS methodology by incorporating this knowledge. We compare our approach with existing smoothing splines, hybrid adaptive splines and wavelet shrinkage techniques on two generated data sets.

Fat Plumes May Reflect the Complex Rheology of the Lower Mantle

NASA Astrophysics Data System (ADS)

Davaille, A.; Carrez, Ph.; Cordier, P.

2018-02-01

Recent tomographic imaging of the mantle below major hot spots shows slow seismic velocities extending down to the core-mantle boundary, confirming the existence of mantle plumes. However, these plumes are much thicker than previously thought. Using new laboratory experiments and scaling laws, we show that thermal plumes developing in a visco-plastic fluid present much larger diameters than plumes developing in a Newtonian fluid. Such a rheology requiring a yield stress is consistent with a lower mantle predominantly deforming by pure dislocation climb. Yield stress values between 1 and 10 MPa, implying dislocation densities between 108 and 1010 m-2, would be sufficient to reproduce the plumes morphology observed in tomographic images.

Presumed filter-feeding in a deep-sea benthic shrimp (Decapoda, Caridea, Stylodactylidae), with records of the deepest occurrence of carideans.

PubMed

Wicksten, Mary; De Grave, Sammy; France, Scott; Kelley, Christopher

2017-01-01

Using the remotely operated vehicle Deep Discoverer , we observed a large stylodactylid shrimp resting on a sedimented sea floor at 4826 m in the Marianas Trench Marine National Monument. The shrimp was not collected but most closely resembled Bathystylodactylus bathyalis , known previously only from a single broken specimen. Video footage shows the shrimp facing into the current and extending its upraised and fringed first and second pereopods, presumably capturing passing particles. The video footage is the first ever to show a living deep-sea stylodactylid and constitutes the deepest record for the family. We provide a list of the deepest reports of caridean shrimps world-wide.

Continued follow-up study of 120 persons born after refusal of application for therapeutic abortion.

PubMed

Forssman, H; Thuwe, I

1981-08-01

An investigation material consisting of 120 persons who were born after refusal of an application for therapeutic abortion, with the same number of controls, has previously been followed up by the writers to the age of 21 years. This follow-up study has now been extended to completion of the 35th year. It is found that in social-psychiatric respects the index cases as a group are still somewhat worse situated than the control cases. However, the differences have to a certain extent levelled out and during the later part of the observation period no statistically significant differences can be demonstrated for any single variable.

Spectral Measurements of Alpha-induced Radioluminescence in Various Gases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brett, Jaclyn; Koehler, Katrina Elizabeth; Bischak, Michael

Radioluminescent emission in Ar, N 2, O 2, and dry air at P=1 atm was observed induced by 5 MeV α particles. The wavelength range with a single detector spanned 250–1100 nm, extending the range well into the UV and IR bands with a single detector. Measured spectral lines for alpha-induced luminescence were corrected for detector transmission and intensities compared to previous work. The exploration of multiple gases over a wide frequency range opens the door to security and remote sensing applications, where different environments are routinely encountered. Finally, this work provides spectra that can be used in guiding futuremore » filter development focusing on remote alpha detection.« less

Spectral Measurements of Alpha-induced Radioluminescence in Various Gases

DOE PAGES

Brett, Jaclyn; Koehler, Katrina Elizabeth; Bischak, Michael; ...

2017-09-06

Radioluminescent emission in Ar, N 2, O 2, and dry air at P=1 atm was observed induced by 5 MeV α particles. The wavelength range with a single detector spanned 250–1100 nm, extending the range well into the UV and IR bands with a single detector. Measured spectral lines for alpha-induced luminescence were corrected for detector transmission and intensities compared to previous work. The exploration of multiple gases over a wide frequency range opens the door to security and remote sensing applications, where different environments are routinely encountered. Finally, this work provides spectra that can be used in guiding futuremore » filter development focusing on remote alpha detection.« less

Seminal magnetic fields from inflato-electromagnetic inflation

NASA Astrophysics Data System (ADS)

Membiela, Federico Agustín; Bellini, Mauricio

2012-10-01

We extend some previous attempts to explain the origin and evolution of primordial magnetic fields during inflation induced from a 5D vacuum. We show that the usual quantum fluctuations of a generalized 5D electromagnetic field cannot provide us with the desired magnetic seeds. We show that special fields without propagation on the extra non-compact dimension are needed to arrive at appreciable magnetic strengths. We also identify a new magnetic tensor field B ij in this kind of extra dimensional theory. Our results are in very good agreement with observational requirements, in particular from TeV blazars and CMB radiation limits we see that primordial cosmological magnetic fields should be close to scale invariance.

Undulator radiation from laser-plasma-accelerated electron beams

NASA Astrophysics Data System (ADS)

Shaw, B.; van Tilborg, J.; Gonsalves, A.; Nakamura, K.; Sokollik, T.; Shiraishi, S.; Mittal, R.; Esarey, E.; Schroeder, C.; Toth, C.; Leemans, W. P.

2012-12-01

Recent experiments coupled electron beams from the LOASIS TREX laser plasma accelerator (LPA) [1, 2, 3] to the Tapered Hybrid Undulator (THUNDER). Using the 1.5m, 66 period undulator, followed by an XUV spectrometer, spontaneous radiation was observed at photon energies extending to 100 eV. Previous experiments have reported visible [4] and soft-x-ray [5] radiation. The purpose of our experiments is to do highly precise, single shot diagnostics of the energy spread and emittance for each electron beam. We present recent results including measurements of electron beam transport through the undulator with and without the use of permanent magnetic quadrapoles, and measurements of XUV spectra up to 100 eV from LPA produced e-beams.

Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC.

PubMed

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Sasaki, T; Sasao, N; Satsounkevitch, I; Sauvage, G; Savard, P; Savine, A Y; Savinov, V; Savva, P; Sawyer, L; Saxon, D H; Says, L P; Sbarra, C; Sbrizzi, A; Scallon, O; Scannicchio, D A; Schaarschmidt, J; Schacht, P; Schäfer, U; Schaetzel, S; Schaffer, A C; Schaile, D; Schaller, M; Schamberger, R D; Schamov, A G; Scharf, V; Schegelsky, V A; Scheirich, D; Schernau, M; Scherzer, M I; Schiavi, C; Schieck, J; Schioppa, M; Schlenker, S; Schlereth, J L; Schmidt, E; Schmidt, M P; Schmieden, K; Schmitt, C; Schmitz, M; Scholte, R C; Schöning, A; Schott, M; Schouten, D; Schovancova, J; Schram, M; Schreiner, A; Schroeder, C; Schroer, N; Schroers, M; Schroff, D; Schuh, S; Schuler, G; Schultes, J; Schultz-Coulon, H-C; Schumacher, J W; Schumacher, M; Schumm, B A; Schune, P; Schwanenberger, C; Schwartzman, A; Schweiger, D; Schwemling, P; Schwienhorst, R; Schwierz, R; Schwindling, J; Scott, W G; Searcy, J; Sedykh, E; Segura, E; Seidel, S C; Seiden, A; Seifert, F; Seixas, J M; Sekhniaidze, G; Seliverstov, D M; Sellden, B; Sellers, G; Seman, M; Semprini-Cesari, N; Serfon, C; Serin, L; Seuster, R; Severini, H; Sevior, M E; Sfyrla, A; Shabalina, E; Shamim, M; Shan, L Y; Shank, J T; Shao, Q T; Shapiro, M; Shatalov, P B; Shaver, L; Shaw, C; Shaw, K; Sherman, D; Sherwood, P; Shibata, A; Shield, P; Shimizu, S; Shimojima, M; Shin, T; Shmeleva, A; Shochet, M J; Shupe, M A; Sicho, P; Sidoti, A; Siebel, A; Siebel, M; Siegert, F; Siegrist, J; Sijacki, D; Silbert, O; Silva, J; Silver, Y; Silverstein, D; Silverstein, S B; Simak, V; Simic, Lj; Simion, S; Simmons, B; Simonyan, M; Sinervo, P; Sinev, N B; Sipica, V; Siragusa, G; Sisakyan, A N; Sivoklokov, S Yu; Sjölin, J; Sjursen, T B; Skinnari, L A; Skovpen, K; Skubic, P; Skvorodnev, N; Slater, M; Slavicek, T; Sliwa, K; Sloan, T J; Sloper, J; Smakhtin, V; Smirnov, S Yu; Smirnov, Y; Smirnova, L N; Smirnova, O; Smith, B C; Smith, D; Smith, K M; Smizanska, M; Smolek, K; Snesarev, A A; Snow, S W; Snow, J; Snuverink, J; Snyder, S; Soares, M; Sobie, R; Sodomka, J; Soffer, A; Solans, C A; Solar, M; Solc, J; Solfaroli Camillocci, E; Solodkov, A A; Solovyanov, O V; Soluk, R; Sondericker, J; Soni, N; Sopko, V; Sopko, B; Sorbi, M; Sosebee, M; Soukharev, A; Spagnolo, S; Spanò, F; Speckmayer, P; Spencer, E; Spighi, R; Spigo, G; Spila, F; Spiriti, E; Spiwoks, R; Spogli, L; Spousta, M; Spreitzer, T; Spurlock, B; St Denis, R D; Stahl, T; Stahlman, J; Stamen, R; Stancu, S N; Stanecka, E; Stanek, R W; Stanescu, C; Stapnes, S; Starchenko, E A; Stark, J; Staroba, P; Starovoitov, P; Stastny, J; Staude, A; Stavina, P; Stavropoulos, G; Steele, G; Stefanidis, E; Steinbach, P; Steinberg, P; Stekl, I; Stelzer, B; Stelzer, H J; Stelzer-Chilton, O; Stenzel, H; Stevenson, K; Stewart, G A; Stiller, W; Stockmanns, T; Stockton, M C; Stodulski, M; Stoerig, K; Stoicea, G; Stonjek, S; Strachota, P; Stradling, A R; Straessner, A; Strandberg, J; Strandberg, S; Strandlie, A; Strang, M; Strauss, M; Strizenec, P; Ströhmer, R; Strom, D M; Strong, J A; Stroynowski, R; Strube, J; Stugu, B; Stumer, I; Sturm, P; Soh, D A; Su, D; Subramania, S; Sugaya, Y; Sugimoto, T; Suhr, C; Suita, K; Suk, M; Sulin, V V; Sultansoy, S; Sumida, T; Sun, X H; Sundermann, J E; Suruliz, K; Sushkov, S; Susinno, G; Sutton, M R; Suzuki, Y; Sviridov, Yu M; Swedish, S; Sykora, I; Sykora, T; Szczygiel, R R; Szeless, B; Szymocha, T; Sánchez, J; Ta, D; Taboada Gameiro, S; Tackmann, K; Taffard, A; Tafirout, R; Taga, A; Takahashi, Y; Takai, H; Takashima, R; Takeda, H; Takeshita, T; Talby, M; Talyshev, A; Tamsett, M C; Tanaka, J; Tanaka, R; Tanaka, S; Tanaka, S; Tanaka, Y; Tani, K; Tappern, G P; Tapprogge, S; Tardif, D; Tarem, S; Tarrade, F; Tartarelli, G F; Tas, P; Tasevsky, M; Tassi, E; Tatarkhanov, M; Taylor, C; Taylor, F E; Taylor, G; Taylor, G N; Taylor, R P; Taylor, W; Teixeira Dias Castanheira, M; Teixeira-Dias, P; Temming, K K; Ten Kate, H; Teng, P K; Tennenbaum-Katan, Y D; Terada, S; Terashi, K; Terron, J; Terwort, M; Testa, M; Teuscher, R J; Tevlin, C M; Thadome, J; Therhaag, J; Theveneaux-Pelzer, T; Thioye, M; Thoma, S; Thomas, J P; Thompson, E N; Thompson, P D; Thompson, P D; Thompson, R J; Thompson, A S; Thomson, E; Thun, R P; Tic, T; Tikhomirov, V O; Tikhonov, Y A; Timmermans, C J W P; Tipton, P; Tique Aires Viegas, F J; Tisserant, S; Tobias, J; Toczek, B; Todorov, T; Todorova-Nova, S; Toggerson, B; Tojo, J; Tokár, S; Tokunaga, K; Tokushuku, K; Tollefson, K; Tomasek, L; Tomasek, M; Tomoto, M; Tompkins, D; Tompkins, L; Toms, K; Tonazzo, A; Tong, G; Tonoyan, A; Topfel, C; Topilin, N D; Torchiani, I; Torrence, E; Torró Pastor, E; Toth, J; Touchard, F; Tovey, D R; Traynor, D; Trefzger, T; Treis, J; Tremblet, L; Tricoli, A; Trigger, I M; Trincaz-Duvoid, S; Trinh, T N; Tripiana, M F; Triplett, N; Trischuk, W; Trivedi, A; Trocmé, B; Troncon, C; Trottier-McDonald, M; Trzupek, A; Tsarouchas, C; Tseng, J C-L; Tsiakiris, M; Tsiareshka, P V; Tsionou, D; Tsipolitis, G; Tsiskaridze, V; Tskhadadze, E G; Tsukerman, I I; Tsulaia, V; Tsung, J-W; Tsuno, S; Tsybychev, D; Tuggle, J M; Turala, M; Turecek, D; Turk Cakir, I; Turlay, E; Tuts, P M; Twomey, M S; Tylmad, M; Tyndel, M; Typaldos, D; Tyrvainen, H; Tzamarioudaki, E; Tzanakos, G; Uchida, K; Ueda, I; Ueno, R; Ugland, M; Uhlenbrock, M; Uhrmacher, M; Ukegawa, F; Unal, G; Underwood, D G; Undrus, A; Unel, G; Unno, Y; Urbaniec, D; Urkovsky, E; Urquijo, P; Urrejola, P; Usai, G; Uslenghi, M; Vacavant, L; Vacek, V; Vachon, B; Vahsen, S; Valderanis, C; Valenta, J; Valente, P; Valentinetti, S; Valkar, S; Valladolid Gallego, E; Vallecorsa, S; Valls Ferrer, J A; Van Berg, R; van der Graaf, H; van der Kraaij, E; van der Poel, E; van der Ster, D; Van Eijk, B; van Eldik, N; van Gemmeren, P; van Kesteren, Z; van Vulpen, I; Vandelli, W; Vandoni, G; Vaniachine, A; Vankov, P; Vannucci, F; Varela Rodriguez, F; Vari, R; Varnes, E W; Varouchas, D; Vartapetian, A; Varvell, K E; Vasilyeva, L; Vassilakopoulos, V I; Vazeille, F; Vegni, G; Veillet, J J; Vellidis, C; Veloso, F; Veness, R; Veneziano, S; Ventura, A; Ventura, D; Ventura, S; Venturi, M; Venturi, N; Vercesi, V; Verducci, M; Verkerke, W; Vermeulen, J C; Vertogardov, L; Vetterli, M C; Vichou, I; Vickey, T; Viehhauser, G H A; Viel, S; Villa, M; Villani, E G; Villaplana Perez, M; Vilucchi, E; Vincter, M G; Vinek, E; Vinogradov, V B; Virchaux, M; Viret, S; Virzi, J; Vitale, A; Vitells, O; Vivarelli, I; Vives Vaque, F; Vlachos, S; Vlasak, M; Vlasov, N; Vogel, A; Vogt, H; Vokac, P; Volpi, M; Volpini, G; von der Schmitt, H; von Loeben, J; von Radziewski, H; von Toerne, E; Vorobel, V; Vorobiev, A P; Vorwerk, V; Vos, M; Voss, R; Voss, T T; Vossebeld, J H; Vovenko, A S; Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vu Anh, T; Vudragovic, D; Vuillermet, R; Vukotic, I; Wagner, W; Wagner, P; Wahlen, H; Walbersloh, J; Walder, J; Walker, R; Walkowiak, W; Wall, R; Waller, P; Wang, C; Wang, H; Wang, J; Wang, J C; Wang, S M; Warburton, A; Ward, C P; Warsinsky, M; Wastie, R; Watkins, P M; Watson, A T; Watson, M F; Watts, G; Watts, S; Waugh, A T; Waugh, B M; Webel, M; Weber, J; Weber, M; Weber, M S; Weber, P; Weidberg, A R; Weingarten, J; Weiser, C; Wellenstein, H; Wellisch, H P; Wells, P S; Wen, M; Wenaus, T; Wendler, S; Weng, Z; Wengler, T; Wenig, S; Wermes, N; Werner, M; Werner, P; Werth, M; Werthenbach, U; Wessels, M; Whalen, K; Wheeler-Ellis, S J; Whitaker, S P; White, A; White, M J; White, S; Whitehead, S R; Whiteson, D; Whittington, D; Wicek, F; Wicke, D; Wickens, F J; Wiedenmann, W; Wielers, M; Wienemann, P; Wiglesworth, C; Wiik, L A M; Wildauer, A; Wildt, M A; Wilhelm, I; Wilkens, H G; Will, J Z; Williams, E; Williams, H H; Willis, W; Willocq, S; Wilson, J A; Wilson, M G; Wilson, A; Wingerter-Seez, I; Winkelmann, S; Winklmeier, F; Wittgen, M; Woehrling, E; Wolter, M W; Wolters, H; Wosiek, B K; Wotschack, J; Woudstra, M J; Wraight, K; Wright, C; Wright, D; Wrona, B; Wu, S L; Wu, X; Wuestenfeld, J; Wulf, E; Wunstorf, R; Wynne, B M; Xaplanteris, L; Xella, S; Xie, S; Xie, Y; Xu, C; Xu, D; Xu, G; Xu, N; Yabsley, B; Yamada, M; Yamamoto, A; Yamamoto, K; Yamamoto, S; Yamamura, T; Yamaoka, J; Yamazaki, T; Yamazaki, Y; Yan, Z; Yang, H; Yang, S; Yang, U K; Yang, Y; Yang, Y; Yang, Z; Yao, W-M; Yao, Y; Yasu, Y; Ye, J; Ye, S; Yilmaz, M; Yoosoofmiya, R; Yorita, K; Yoshida, R; Young, C; Youssef, S P; Yu, D; Yu, J; Yu, J; Yuan, J; Yuan, L; Yurkewicz, A; Zaets, V G; Zaidan, R; Zaitsev, A M; Zajacova, Z; Zalite, Yo K; Zambrano, V; Zanello, L; Zarzhitsky, P; Zaytsev, A; Zdrazil, M; Zeitnitz, C; Zeller, M; Zema, P F; Zemla, A; Zendler, C; Zenin, A V; Zenin, O; Zenis, T; Zenonos, Z; Zenz, S; Zerwas, D; Zevi Della Porta, G; Zhan, Z; Zhang, H; Zhang, J; Zhang, Q; Zhang, X; Zhao, L; Zhao, T; Zhao, Z; Zhemchugov, A; Zheng, S; Zhong, J; Zhou, B; Zhou, N; Zhou, Y; Zhu, C G; Zhu, H; Zhu, Y; Zhuang, X; Zhuravlov, V; Zilka, B; Zimmermann, R; Zimmermann, S; Zimmermann, S; Ziolkowski, M; Zitoun, R; Zivković, L; Zmouchko, V V; Zobernig, G; Zoccoli, A; Zolnierowski, Y; Zsenei, A; Zur Nedden, M; Zutshi, V

2010-10-15

A search for new heavy particles manifested as resonances in two-jet final states is presented. The data were produced in 7 TeV proton-proton collisions by the LHC and correspond to an integrated luminosity of 315  nb⁻¹ collected by the ATLAS detector. No resonances were observed. Upper limits were set on the product of cross section and signal acceptance for excited-quark (q*) production as a function of q* mass. These exclude at the 95% C.L. the q* mass interval 0.30

Catecholamines and in vitro growth of pathogenic bacteria: enhancement of growth varies greatly among bacterial species

NASA Technical Reports Server (NTRS)

Belay, Tesfaye; Aviles, Hernan; Vance, Monique; Fountain, Kimberly; Sonnenfeld, Gerald

2003-01-01

The purpose of this study was to examine the effects of catecholamines on in vitro growth of a range of bacterial species, including anaerobes. Bacteria tested included: Porphyromonas gingivalis, Bacteriodes fragilis, Shigella boydii, Shigella sonnie, Enterobacter Sp, and Salmonella choleraesuis. The results of the current study indicated that supplementation of bacterial cultures in minimal medium with norepinephrine or epinephrine did not result in increased growth of bacteria. Positive controls involving treatment of Escherichia coli with catecholamines did result in increased growth of that bacterial species. The results of the present study extend previous observations that showed differential capability of catecholamines to enhance bacterial growth in vitro.

Signs Indicating Imminent Death in Escherichia coli-Infected Broilers.

PubMed

Matthijs, M G R; Nieuwenhuis, J F; Dwars, R M

2017-09-01

Broilers were observed during 9 days for clinical signs after intratracheal inoculation at 8 days of age with 10 7 E. coli 506. It was determined if these signs were predictive for imminent death. Hourly observations were made daily from a distance of 1-2 m and nightly by camera observation, with respect to the following parameters: level of attention, locomotory activity, posture and appearance, interaction, and impairment of respiration. For deviations of the normal state for these five parameters (i.e., typical clinical signs of disease), scores were defined in up to four classes. The periods of time elapsing from attaining a score for the first time to death were registered per bird for each score for each parameter. Of 114 birds, 85 did not present typical signs of illness as described, and 29 presented the following clinical history: 25 died after presenting signs of illness, 2 died without previous signs, 1 fell ill but survived, and 1 fell ill and recovered. Extended clinical examination was performed in birds presenting clinical signs; temperature, heart rate, respiratory rate, and subcutaneous capillary refill time were measured. The level of attention, and posture and appearance were affected most often in ill birds; 25% of these birds died within 5 and 4 hr, respectively; 50% died within 12 hr; and 75% died within 20 and 19 hr, respectively. Any of these typical signs of illness visible from 1-2 m indicated imminent death, with 75% of the birds dying within 20 hr. Measurements resulting from extended clinical examination proved of lesser predictive value. From these observations, a protocol for intervention to prevent animal suffering may be designed.

Nonsurgically retreated root filled teeth--radiographic findings after 20-27 years.

PubMed

Fristad, I; Molven, O; Halse, A

2004-01-01

To identify periapical changes in nonsurgically retreated root-filled teeth 20-27 years after root canal treatment. From an original material of 429 roots, retreated by undergraduate students in a teaching clinic, 112 roots in 70 individuals could be evaluated radiographically 20-27 years after treatment. The same roots had been studied 10-17 years earlier. The periapical condition was registered and compared by three observers in two series of intraoral radiographs taken 10-17 and 20-27 years after treatment. A retrospective analysis was performed to gain information about probable endodontic and nonendodontic reasons for extractions of lost roots, by evaluating their periapical status immediately after retreatment and at the 10-17-year follow-up. Favourable outcomes were observed in 11 roots that had radiolucencies at the 10-17-year follow-up. Eight of these roots had periapical pathosis preoperatively, five of them filled with surplus root filling material. The percentage of cases recorded as normal condition at the final follow-up was 95.5%, including five cases initially recorded with increased width of the apical periodontal space. Delayed healing as a result of surplus root filling material explained most of the cases with favourable outcome assessed many years after treatment. Twenty-eight roots were lost because of extraction during the observation period, 17 during the last 10 years. Based on status at previous follow-ups, endodontic failure seems to represent a minor reason for extraction in the material. Late periapical changes, with more successful cases, were recorded when a 10-17-year follow-up after root canal treatment was extended for another 10 years. Persistent asymptomatic periapical radiolucencies, especially those with overfill, should generally not be classified as failures, as many of them will heal after an extended observation period.

The 3CR Chandra Snapshot Survey: Extragalactic Radio Sources with Redshifts between 1 and 1.5

NASA Astrophysics Data System (ADS)

Stuardi, C.; Missaglia, V.; Massaro, F.; Ricci, F.; Liuzzo, E.; Paggi, A.; Kraft, R. P.; Tremblay, G. R.; Baum, S. A.; O’Dea, C. P.; Wilkes, B. J.; Kuraszkiewicz, J.; Forman, W. R.; Harris, D. E.

2018-04-01

The aim of this paper is to present an analysis of newly acquired X-ray observations of 16 extragalactic radio sources listed in the Third Cambridge Revised (3CR) catalog and not previously observed by Chandra. Observations were performed during Chandra Cycle 17, extending X-ray coverage for the 3CR extragalactic catalog up to z = 1.5. Among the 16 targets, two lie at z < 0.5 (3CR 27 at z = 0.184 and 3CR 69 at z = 0.458) all of the remaining 14 have redshifts between 1.0 and 1.5. In the current sample, there are three compact steep spectrum (CSS) sources, three quasars, and an FR I radio galaxy, while the other nine are FR II radio galaxies. All radio sources have an X-ray counterpart. We measured nuclear X-ray fluxes as well as X-ray emission associated with radio jet knots, hotspots, or lobes in three energy bands: soft (0.5–1 keV), medium (1–2 keV), and hard (2–7 keV). We also performed standard X-ray spectral analysis for the four brightest nuclei. We discovered X-ray emission associated with the radio lobe of 3CR 124, a hotspot of the quasar 3CR 220.2, another hotspot of the radio galaxy 3CR 238, and the jet knot of 3CR 297. We also detected extended X-ray emission around the nuclear region of 3CR 124 and 3CR 297 on scales of several tens of kiloparsecs. Finally, we present an update on the X-ray observations performed with Chandra and XMM-Newton on the entire 3CR extragalactic catalog.

The Star Formation Main Sequence in the Hubble Space Telescope Frontier Fields

NASA Astrophysics Data System (ADS)

Santini, Paola; Fontana, Adriano; Castellano, Marco; Di Criscienzo, Marcella; Merlin, Emiliano; Amorin, Ricardo; Cullen, Fergus; Daddi, Emanuele; Dickinson, Mark; Dunlop, James S.; Grazian, Andrea; Lamastra, Alessandra; McLure, Ross J.; Michałowski, Michał. J.; Pentericci, Laura; Shu, Xinwen

2017-09-01

We investigate the relation between star formation rate (SFR) and stellar mass (M), I.e., the main sequence (MS) relation of star-forming galaxies, at 1.3≤slant z< 6 in the first four Hubble Space Telescope (HST) Frontier Fields, on the basis of rest-frame UV observations. Gravitational lensing combined with deep HST observations allows us to extend the analysis of the MS down to {log} M/{M}⊙ ˜ 7.5 at z≲ 4 and {log} M/{M}⊙ ˜ 8 at higher redshifts, a factor of ˜10 below most previous results. We perform an accurate simulation to take into account the effect of observational uncertainties and correct for the Eddington bias. This step allows us to reliably measure the MS and in particular its slope. While the normalization increases with redshift, we fit an unevolving and approximately linear slope. We nicely extend to lower masses the results of brighter surveys. Thanks to the large dynamic range in mass and by making use of the simulation, we analyzed any possible mass dependence of the dispersion around the MS. We find tentative evidence that the scatter decreases with increasing mass, suggesting a larger variety of star formation histories in low-mass galaxies. This trend agrees with theoretical predictions and is explained as either a consequence of the smaller number of progenitors of low-mass galaxies in a hierarchical scenario and/or of the efficient but intermittent stellar feedback processes in low-mass halos. Finally, we observe an increase in the SFR per unit stellar mass with redshift milder than predicted by theoretical models, implying a still incomplete understanding of the processes responsible for galaxy growth.

Linking atmospheric synoptic transport, cloud phase, surface energy fluxes, and sea-ice growth: observations of midwinter SHEBA conditions

NASA Astrophysics Data System (ADS)

Persson, P. Ola G.; Shupe, Matthew D.; Perovich, Don; Solomon, Amy

2017-08-01

Observations from the Surface Heat Budget of the Arctic Ocean (SHEBA) project are used to describe a sequence of events linking midwinter long-range advection of atmospheric heat and moisture into the Arctic Basin, formation of supercooled liquid water clouds, enhancement of net surface energy fluxes through increased downwelling longwave radiation, and reduction in near-surface conductive heat flux loss due to a warming of the surface, thereby leading to a reduction in sea-ice bottom growth. The analyses provide details of two events during Jan. 1-12, 1998, one entering the Arctic through Fram Strait and the other from northeast Siberia; winter statistics extend the results. Both deep, precipitating frontal clouds and post-frontal stratocumulus clouds impact the surface radiation and energy budget. Cloud liquid water, occurring preferentially in stratocumulus clouds extending into the base of the inversion, provides the strongest impact on surface radiation and hence modulates the surface forcing, as found previously. The observations suggest a minimum water vapor threshold, likely case dependent, for producing liquid water clouds. Through responses to the radiative forcing and surface warming, this cloud liquid water also modulates the turbulent and conductive heat fluxes, and produces a thermal wave penetrating into the sea ice. About 20-33 % of the observed variations of bottom ice growth can be directly linked to variations in surface conductive heat flux, with retarded ice growth occurring several days after these moisture plumes reduce the surface conductive heat flux. This sequence of events modulate pack-ice wintertime environmental conditions and total ice growth, and has implications for the annual sea-ice evolution, especially for the current conditions of extensive thinner ice.

Contributions of Attentional Style and Previous Experience to 4-Month-Old Infants' Categorization

ERIC Educational Resources Information Center

Kovack-Lesh, Kristine A.; Oakes, Lisa M.; McMurray, Bob

2012-01-01

We examined how infants' categorization is jointly influenced by previous experience and how much they shift their gaze back and forth between stimuli. Extending previous findings reported by K. A. Kovack-Lesh, J. S. Horst, and L. M. Oakes (2008), we found that 4-month-old infants' (N = 122) learning of the exclusive category of "cats" was related…

The Spectroscopic Evolution of the Symbiotic-like Recurrent Nova V407 Cygni During Its 2010 Outburst. 2. The Circumstellar Environment and the Aftermath

NASA Technical Reports Server (NTRS)

Shore, S. N.; Wahlgren, G. M.; Augusteijn, T.; Liimets, T.; Koubsky, P.; Slechta, M.; Votruba, V.

2011-01-01

The nova outburst of V407 Cyg in 2010 Mar. 10 was the first observed for this star but its close resemblance to the well known symbiotic-like recurrent nova RS Oph suggests that it is also a member of this rare type of Galactic novae. The nova was the first detected at gamma-ray energies and is the first known nova explosion for this system. The extensive multiwavelength coverage of this outburst makes it an ideal comparison with the few other outbursts known for similar systems. We extend our previous analysis of the Mira and the expanding shock from the explosion to detail the time development of the photoionized Mira wind, circumstellar medium, and shocked circumstellar environment to derive their physical parameters and how they relate to large scale structure of the environment, extending the previous coverage to more than 500 days after outburst. We use optical spectra obtained at high resolution with the Nordic Optical Telescope (NOT) (R approx. =.45000 to 65000) and medium resolution Ondrejov Observatory (R approx. = 12000) data and compare the line variations with publicly available archival measurements at 30 GHz OVNR and at X-rays with Swift during the first four months of the outburst, through the end of the epoch of strong XR emission. We use nebular diagnostics and high resolution profile variations to derive the densities and locations of the extended emission. We find that the higher the ionization and/or the higher the excitation energy, the more closely the profiles resemble the He II/Ca V-type high velocity shock profile discussed in Paper I. This also accounts for the comparative development of the [N II] and [O III] isoelectronic transitions: the [O III] 4363A profile does not show the low velocity peaks while the excited [N II] 5754A does. If nitrogen is mainly N(+3) or higher in the shock, the upper state of the [N II] nebular lines will contribute but if the oxygen is O(+2) then this line is formed by recombination, masking the nebular contributor, and the lower states are collisionally quenched but emit from the low density surroundings. Absorption lines of Fe-peak ions formed in the Mira wind were visible as P Cyg profiles at low velocity before Day 69, around the time of the X-ray peak and we identified many absorption transitions without accompanying emission for metal lines. The H Balmer lines showed strong P Cyg absorption troughs that weakened during the 2010 observing period, through Day 128. The Fe-peak line profiles and flux variations were different for permitted and forbidden transitions: the E1 transitions were not visible after Day 128 but had shown a narrow peak superimposed on an extended (200 km/s) blue wing, while the M1 and E2 transitions persisted to Day 529, the last observation, and showed extended redshifted wings up of the same velocity. We distinguish the components from the shock, the photoionized environment, and the chromosphere and inner Mira wind using spectra taken more than one year after outburst. The multiple shells and radiative excitation phenomenology are similar to those recently cited for GRBs and SNIa .

Modeling Reconnection-Driven Solar Polar Jets with Gravity and Wind

NASA Astrophysics Data System (ADS)

Karpen, Judith T.; DeVore, C. R.; Antiochos, S. K.

2013-07-01

Solar polar jets are dynamic, narrow, radially extended structures observed in EUV emission. They have been found to originate within the open magnetic field of coronal holes in “anemone” regions, which are generally accepted to be intrusions of opposite polarity. The associated embedded-dipole topology consists of a spine line emanating from a null point atop a dome-shaped fan surface. Previous work (Pariat et al. 2009, 2010) has validated the idea that magnetic free energy stored on twisted closed field lines within the fan surface can be released explosively by the onset of fast reconnection between the highly stressed closed field inside the null and the unstressed open field outside (Antiochos 1996). The simulations showed that a dense jet comprising a nonlinear, torsional Alfven wave is ejected into the outer corona on the newly reconnected open field lines. While proving the principle of the basic model, those simulations neglected the important effects of gravity, the solar wind, and an expanding spherical geometry. We introduce those additional physical processes in new simulations of reconnection-driven jets, to determine whether the model remains robust in the resulting more realistic setting, and to begin establishing the signatures of the jets in the inner heliosphere for comparison with observations. Initial results demonstrate explosive energy release and a jet in the low corona very much like that in the earlier Cartesian, gravity-free, static-atmosphere runs. We report our analysis of the results, their comparison with previous work, and their implications for observations. This work was supported by NASA’s LWS TR&T program.Abstract (2,250 Maximum Characters): Solar polar jets are dynamic, narrow, radially extended structures observed in EUV emission. They have been found to originate within the open magnetic field of coronal holes in “anemone” regions, which are generally accepted to be intrusions of opposite polarity. The associated embedded-dipole topology consists of a spine line emanating from a null point atop a dome-shaped fan surface. Previous work (Pariat et al. 2009, 2010) has validated the idea that magnetic free energy stored on twisted closed field lines within the fan surface can be released explosively by the onset of fast reconnection between the highly stressed closed field inside the null and the unstressed open field outside (Antiochos 1996). The simulations showed that a dense jet comprising a nonlinear, torsional Alfven wave is ejected into the outer corona on the newly reconnected open field lines. While proving the principle of the basic model, those simulations neglected the important effects of gravity, the solar wind, and an expanding spherical geometry. We introduce those additional physical processes in new simulations of reconnection-driven jets, to determine whether the model remains robust in the resulting more realistic setting, and to begin establishing the signatures of the jets in the inner heliosphere for comparison with observations. Initial results demonstrate explosive energy release and a jet in the low corona very much like that in the earlier Cartesian, gravity-free, static-atmosphere runs. We report our analysis of the results, their comparison with previous work, and their implications for observations. This work was supported by NASA’s LWS TR&T program.

Extended radio emission and the nature of blazars

NASA Astrophysics Data System (ADS)

Antonucci, R. R. J.; Ulvestad, J. S.

1985-07-01

The VLA has been used at 20 cm to map all 23 of the 54 confirmed blazars listed in the Angel and Stockman review paper that had not been mapped before at high resolution. In addition, data on most of the previously mapped blazars have been reprocessed in order to achieve higher dynamic range. Extended emission has been detected associated with 49 of the 54 objects. The extended radio emission has been used to test the hypothesis that blazars are normal radio galaxies and radio quasars viewed along the jet axes. It is found that blazars have substantial extended power, consistent with this hypothesis. The ratio of core to extended radio emission has been studied as a possible indicator of viewing aspect or beaming intensity.

Perceived neighborhood quality, sleep quality, and health status: Evidence from the Survey of the Health of Wisconsin

PubMed Central

Hale, Lauren; Hill, Terrence D.; Friedman, Elliot; Nieto, F. Javier; Galvao, Loren W.; Engelman, Corinne D.; Malecki, Kristen M.C.; Peppard, Paul E.

2013-01-01

Why does living in a disadvantaged neighborhood predict poorer mental and physical health? Recent research focusing on the Southwestern United States suggests that disadvantaged neighborhoods favor poor health, in part, because they undermine sleep quality. Building on previous research, we test whether this process extends to the Midwestern United States. Specifically, we use cross-sectional data from the Survey of the Health of Wisconsin (SHOW), a statewide probability sample of Wisconsin adults, to examine whether associations among perceived neighborhood quality (e.g., perceptions of crime, litter, and pleasantness in the neighborhood) and health status (overall self-rated health and depression) are mediated by overall sleep quality (measured as self-rated sleep quality and physician diagnosis of sleep apnea). We find that perceptions of low neighborhood quality are associated with poorer self-rated sleep quality, poorer self-rated health, and more depressive symptoms. We also observe that poorer self-rated sleep quality is associated with poorer self-rated health and more depressive symptoms. Our mediation analyses indicate that self-rated sleep quality partially mediates the link between perceived neighborhood quality and health status. Specifically, self-rated sleep quality explains approximately 20% of the association between neighborhood quality and self-rated health and nearly 19% of the association between neighborhood quality and depression. Taken together, these results confirm previous research and extend the generalizability of the indirect effect of perceived neighborhood context on health status through sleep quality. PMID:22901794

Perceived neighborhood quality, sleep quality, and health status: evidence from the Survey of the Health of Wisconsin.

PubMed

Hale, Lauren; Hill, Terrence D; Friedman, Elliot; Nieto, F Javier; Galvao, Loren W; Engelman, Corinne D; Malecki, Kristen M C; Peppard, Paul E

2013-02-01

Why does living in a disadvantaged neighborhood predict poorer mental and physical health? Recent research focusing on the Southwestern United States suggests that disadvantaged neighborhoods favor poor health, in part, because they undermine sleep quality. Building on previous research, we test whether this process extends to the Midwestern United States. Specifically, we use cross-sectional data from the Survey of the Health of Wisconsin (SHOW), a statewide probability sample of Wisconsin adults, to examine whether associations among perceived neighborhood quality (e.g., perceptions of crime, litter, and pleasantness in the neighborhood) and health status (overall self-rated health and depression) are mediated by overall sleep quality (measured as self-rated sleep quality and physician diagnosis of sleep apnea). We find that perceptions of low neighborhood quality are associated with poorer self-rated sleep quality, poorer self-rated health, and more depressive symptoms. We also observe that poorer self-rated sleep quality is associated with poorer self-rated health and more depressive symptoms. Our mediation analyses indicate that self-rated sleep quality partially mediates the link between perceived neighborhood quality and health status. Specifically, self-rated sleep quality explains approximately 20% of the association between neighborhood quality and self-rated health and nearly 19% of the association between neighborhood quality and depression. Taken together, these results confirm previous research and extend the generalizability of the indirect effect of perceived neighborhood context on health status through sleep quality. Copyright © 2012 Elsevier Ltd. All rights reserved.

Agent-based modeling of the spread of the 1918-1919 flu in three Canadian fur trading communities.

PubMed

O'Neil, Caroline A; Sattenspiel, Lisa

2010-01-01

Previous attempts to study the 1918-1919 flu in three small communities in central Manitoba have used both three-community population-based and single-community agent-based models. These studies identified critical factors influencing epidemic spread, but they also left important questions unanswered. The objective of this project was to design a more realistic agent-based model that would overcome limitations of earlier models and provide new insights into these outstanding questions. The new model extends the previous agent-based model to three communities so that results can be compared to those from the population-based model. Sensitivity testing was conducted, and the new model was used to investigate the influence of seasonal settlement and mobility patterns, the geographic heterogeneity of the observed 1918-1919 epidemic in Manitoba, and other questions addressed previously. Results confirm outcomes from the population-based model that suggest that (a) social organization and mobility strongly influence the timing and severity of epidemics and (b) the impact of the epidemic would have been greater if it had arrived in the summer rather than the winter. New insights from the model suggest that the observed heterogeneity among communities in epidemic impact was not unusual and would have been the expected outcome given settlement structure and levels of interaction among communities. Application of an agent-based computer simulation has helped to better explain observed patterns of spread of the 1918-1919 flu epidemic in central Manitoba. Contrasts between agent-based and population-based models illustrate the advantages of agent-based models for the study of small populations. © 2010 Wiley-Liss, Inc.

Validation of Model Output versus ADCP Observations on the PR Insular Shelf, Part 2: Are all Sites the Same?

NASA Astrophysics Data System (ADS)

Ramos Valle, A.

2016-02-01

We have previously compared the output from three oceanographic models against observed data from an ADCP at a common grid point location on the zonally oriented, southwestern Puerto Rico shelf that extends into the northern Caribbean Sea. The three models were: 1) AMSEAS (NCOM), 2) Regional ROMS and 3) a higher resolution version of ROMS nested within the Regional ROMS. These models faced great difficulty in accurately depicting the bathymetry of the ocean in the PR-USVI archipelago which is characterized by small islands, narrow insular shelves, steep slopes and deep water beyond. The resulting validations of the three models versus the ADCP at the selected location were poor. However, the insight we gained into the behavior of the models during the validation process suggested that models might do a better job at simulating currents across the inter-island straits that connect the Atlantic Ocean with the Caribbean Sea than along the insular Caribbean or Atlantic coastlines. We therefore focused our attention on expanding our previous research by performing a similar analysis using the ROMS model against ADCP observations in the Mona Passage, west of PR. This new ADCP location exhibits bathymetric features that are smoother, less complex, and better represented in the Regional ROMS model while flows at the site are stronger than at the previous ADCP site at La Parguera. Statistical time-series analyses are performed on model and ADCP flow velocity time series to quantify the model's skill. Results indicate that ROMS does a much better job at simulating ocean currents at the Mona Passage site than at La Parguera. Dynamical and numerical differences that might explain the spatially varying model skill are considered. In summary: model skill validation sites around PR are not all the same.

The AstraLux Multiplicity Survey: Extension to Late M-dwarfs

NASA Astrophysics Data System (ADS)

Janson, Markus; Bergfors, Carolina; Brandner, Wolfgang; Kudryavtseva, Natalia; Hormuth, Felix; Hippler, Stefan; Henning, Thomas

2014-07-01

The distribution of multiplicity among low-mass stars is a key issue to understanding the formation of stars and brown dwarfs, and recent surveys have yielded large enough samples of nearby low-mass stars to study this issue statistically to good accuracy. Previously, we have presented a multiplicity study of ~700 early/mid M-type stars observed with the AstraLux high-resolution Lucky Imaging cameras. Here, we extend the study of multiplicity in M-type stars through studying 286 nearby mid/late M-type stars, bridging the gap between our previous study and multiplicity studies of brown dwarfs. Most of the targets have been observed more than once, allowing us to assess common proper motion to confirm companionship. We detect 68 confirmed or probable companions in 66 systems, of which 41 were previously undiscovered. Detections are made down to the resolution limit of ~100 mas of the instrument. The raw multiplicity in the AstraLux sensitivity range is 17.9%, leading to a total multiplicity fraction of 21%-27% depending on the mass ratio distribution, which is consistent with being flat down to mass ratios of ~0.4, but cannot be stringently constrained below this value. The semi-major axis distribution is well represented by a log-normal function with μa = 0.78 and σa = 0.47, which is narrower and peaked at smaller separations than for a Sun-like sample. This is consistent with a steady decrease in average semi-major axis from the highest-mass binary stars to the brown dwarf binaries. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institute for Astronomy and the Instituto de Astrofísica de Andalucía (CSIC).

A randomized, double-blind study of the efficacy and tolerability of extended-release quetiapine fumarate (quetiapine XR) monotherapy in patients with major depressive disorder

PubMed Central

Wang, Gang; McIntyre, Alexander; Earley, Willie R; Raines, Shane R; Eriksson, Hans

2014-01-01

Objectives To evaluate the efficacy and tolerability of once-daily extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with major depressive disorder (MDD). Patients and methods This was a 10-week (8-week active treatment/2-week post-treatment) randomized, double-blind, placebo- and active-controlled study (D1448C00004). Patients received quetiapine XR 150 mg/day, escitalopram 10 mg/day, or placebo; patients with an inadequate response (<20% improvement in Montgomery–Åsberg Depression Rating Scale [MADRS] total score) at week two received double-dose treatment. The primary end point was week eight change from randomization in MADRS total score. Secondary end points included MADRS response (≥50% improvement) and remission (score ≤8); Hamilton Rating Scale for Depression total and item 1; Hamilton Rating Scale for Anxiety total, psychic, and somatic; Clinical Global Impressions – Severity of Illness total; Pittsburgh Sleep Quality Index (PSQI) global; and Quality of Life Enjoyment and Satisfaction Questionnaire – Short Form percentage maximum total scores. Tolerability was assessed throughout. Results A total of 471 patients was randomized. No significant improvements in MADRS total score were observed at week eight (last observation carried forward) with either active treatment (quetiapine XR, −17.21 [P=0.174]; escitalopram, −16.73 [P=0.346]) versus placebo (−15.61). There were no significant differences in secondary end points versus placebo, with the exception of week-eight change in PSQI global score (quetiapine XR, −4.96 [P<0.01] versus placebo, −3.37). Mixed-model repeated-measures analysis of observed-case data suggested that the primary analysis may not be robust. Most commonly reported adverse events included dry mouth, somnolence, and dizziness for quetiapine XR, and headache and nausea for escitalopram. Conclusion In this study, neither quetiapine XR (150/300 mg/day) nor escitalopram (10/20 mg/day) showed significant separation from placebo. Both compounds have been shown previously to be effective in the treatment of MDD; possible reasons for this failed study are discussed. Quetiapine XR was generally well tolerated, with a profile similar to that reported previously. PMID:24511235

Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents

PubMed Central

2016-01-01

Redox neutral photocatalytic transformations often require careful pairing of the substrates and photoredox catalysts in order to achieve a catalytic cycle. This can limit the range of viable transformations, as we recently observed in attempting to extend the scope of the photocatalytic synthesis of N-heterocycles using silicon amine protocol (SLAP) reagents to include starting materials that require higher oxidation potentials. We now report that the inclusion of Lewis acids in photocatalytic reactions of organosilanes allows access to a distinct reaction pathway featuring an Ir(III)*/Ir(IV) couple instead of the previously employed Ir(III)*/Ir(II) pathway, enabling the transformation of aromatic and aliphatic aldehydes to thiomorpholines and thiazepanes. The role of the Lewis acid in accepting an electron—either directly or via coordination to an imine—can be extended to other classes of photocatalysts and transformations, including oxidative cyclizations. The combination of light induced reactions and Lewis acids therefore promises access to new pathways and transformations that are not viable using the photocatalysts alone. PMID:28149955

First experimental evidence of hydrodynamic tunneling of ultra–relativistic protons in extended solid copper target at the CERN HiRadMat facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmidt, R.; Grenier, D.; Wollmann, D.

2014-08-15

A novel experiment has been performed at the CERN HiRadMat test facility to study the impact of the 440 GeV proton beam generated by the Super Proton Synchrotron on extended solid copper cylindrical targets. Substantial hydrodynamic tunneling of the protons in the target material has been observed that leads to significant lengthening of the projectile range, which confirms our previous theoretical predictions [N. A. Tahir et al., Phys. Rev. Spec. Top.-Accel. Beams 15, 051003 (2012)]. Simulation results show very good agreement with the experimental measurements. These results have very important implications on the machine protection design for powerful machines like themore » Large Hadron Collider (LHC), the future High Luminosity LHC, and the proposed huge 80 km circumference Future Circular Collider, which is currently being discussed at CERN. Another very interesting outcome of this work is that one may also study the field of High Energy Density Physics at this test facility.« less

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

PubMed

Mansfeld, Johannes; Urban, Nadine; Priebe, Steffen; Groth, Marco; Frahm, Christiane; Hartmann, Nils; Gebauer, Juliane; Ravichandran, Meenakshi; Dommaschk, Anne; Schmeisser, Sebastian; Kuhlow, Doreen; Monajembashi, Shamci; Bremer-Streck, Sibylle; Hemmerich, Peter; Kiehntopf, Michael; Zamboni, Nicola; Englert, Christoph; Guthke, Reinhard; Kaleta, Christoph; Platzer, Matthias; Sühnel, Jürgen; Witte, Otto W; Zarse, Kim; Ristow, Michael

2015-12-01

Ageing has been defined as a global decline in physiological function depending on both environmental and genetic factors. Here we identify gene transcripts that are similarly regulated during physiological ageing in nematodes, zebrafish and mice. We observe the strongest extension of lifespan when impairing expression of the branched-chain amino acid transferase-1 (bcat-1) gene in C. elegans, which leads to excessive levels of branched-chain amino acids (BCAAs). We further show that BCAAs reduce a LET-363/mTOR-dependent neuro-endocrine signal, which we identify as DAF-7/TGFβ, and that impacts lifespan depending on its related receptors, DAF-1 and DAF-4, as well as ultimately on DAF-16/FoxO and HSF-1 in a cell-non-autonomous manner. The transcription factor HLH-15 controls and epistatically synergizes with BCAT-1 to modulate physiological ageing. Lastly and consistent with previous findings in rodents, nutritional supplementation of BCAAs extends nematodal lifespan. Taken together, BCAAs act as periphery-derived metabokines that induce a central neuro-endocrine response, culminating in extended healthspan.

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

PubMed Central

Mansfeld, Johannes; Urban, Nadine; Priebe, Steffen; Groth, Marco; Frahm, Christiane; Hartmann, Nils; Gebauer, Juliane; Ravichandran, Meenakshi; Dommaschk, Anne; Schmeisser, Sebastian; Kuhlow, Doreen; Monajembashi, Shamci; Bremer-Streck, Sibylle; Hemmerich, Peter; Kiehntopf, Michael; Zamboni, Nicola; Englert, Christoph; Guthke, Reinhard; Kaleta, Christoph; Platzer, Matthias; Sühnel, Jürgen; Witte, Otto W.; Zarse, Kim; Ristow, Michael

2015-01-01

Ageing has been defined as a global decline in physiological function depending on both environmental and genetic factors. Here we identify gene transcripts that are similarly regulated during physiological ageing in nematodes, zebrafish and mice. We observe the strongest extension of lifespan when impairing expression of the branched-chain amino acid transferase-1 (bcat-1) gene in C. elegans, which leads to excessive levels of branched-chain amino acids (BCAAs). We further show that BCAAs reduce a LET-363/mTOR-dependent neuro-endocrine signal, which we identify as DAF-7/TGFβ, and that impacts lifespan depending on its related receptors, DAF-1 and DAF-4, as well as ultimately on DAF-16/FoxO and HSF-1 in a cell-non-autonomous manner. The transcription factor HLH-15 controls and epistatically synergizes with BCAT-1 to modulate physiological ageing. Lastly and consistent with previous findings in rodents, nutritional supplementation of BCAAs extends nematodal lifespan. Taken together, BCAAs act as periphery-derived metabokines that induce a central neuro-endocrine response, culminating in extended healthspan. PMID:26620638

Nonlinear Diamagnetic Stabilization of Double Tearing Modes in Cylindrical MHD Simulations

NASA Astrophysics Data System (ADS)

Abbott, Stephen; Germaschewski, Kai

2014-10-01

Double tearing modes (DTMs) may occur in reversed-shear tokamak configurations if two nearby rational surfaces couple and begin reconnecting. During the DTM's nonlinear evolution it can enter an ``explosive'' growth phase leading to complete reconnection, making it a possible driver for off-axis sawtooth crashes. Motivated by similarities between this behavior and that of the m = 1 kink-tearing mode in conventional tokamaks we investigate diamagnetic drifts as a possible DTM stabilization mechanism. We extend our previous linear studies of an m = 2 , n = 1 DTM in cylindrical geometry to the fully nonlinear regime using the MHD code MRC-3D. A pressure gradient similar to observed ITB profiles is used, together with Hall physics, to introduce ω* effects. We find the diamagnetic drifts can have a stabilizing effect on the nonlinear DTM through a combination of large scale differential rotation and mechanisms local to the reconnection layer. MRC-3D is an extended MHD code based on the libMRC computational framework. It supports nonuniform grids in curvilinear coordinates with parallel implicit and explicit time integration.

Absolute Spectrophotometric Calibration to 1% from the FUV through the near-IR

NASA Astrophysics Data System (ADS)

Finley, David

2005-07-01

We propose a significant improvement to the existing HST calibration. The current calibration is based on three primary DA white dwarf standards, GD 71, GD 153, and G 191-B2B. The standard fluxes are calculated using NLTE models, with effective temperatures and gravities that were derived from Balmer line fits using LTE models. We propose to improve the accuracy and internal consistency of the calibration by deriving corrected effective temperatures and gravities based on fitting the observed line profiles with updated NLTE models, and including the fit results from multiple STIS spectra, rather than the {usually} 1 or 2 ground-based spectra used previously. We will also determine the fluxes for 5 new, fainter primary or secondary standards, extending the standard V magnitude lower limit from 13.4 to 16.5, and extending the wavelength coverage from 0.1 to 2.5 micron. The goal is to achieve an overall flux accuracy of 1%, which will be needed, for example, for the upcoming supernova survey missions to measure the equation of state of the dark energy that is accelerating the expansion of the universe.

A variational approach to moment-closure approximations for the kinetics of biomolecular reaction networks

NASA Astrophysics Data System (ADS)

Bronstein, Leo; Koeppl, Heinz

2018-01-01

Approximate solutions of the chemical master equation and the chemical Fokker-Planck equation are an important tool in the analysis of biomolecular reaction networks. Previous studies have highlighted a number of problems with the moment-closure approach used to obtain such approximations, calling it an ad hoc method. In this article, we give a new variational derivation of moment-closure equations which provides us with an intuitive understanding of their properties and failure modes and allows us to correct some of these problems. We use mixtures of product-Poisson distributions to obtain a flexible parametric family which solves the commonly observed problem of divergences at low system sizes. We also extend the recently introduced entropic matching approach to arbitrary ansatz distributions and Markov processes, demonstrating that it is a special case of variational moment closure. This provides us with a particularly principled approximation method. Finally, we extend the above approaches to cover the approximation of multi-time joint distributions, resulting in a viable alternative to process-level approximations which are often intractable.

Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin

NASA Astrophysics Data System (ADS)

Lermyte, Frederik; Łącki, Mateusz Krzysztof; Valkenborg, Dirk; Gambin, Anna; Sobott, Frank

2017-01-01

Owing to its versatility, electron transfer dissociation (ETD) has become one of the most commonly utilized fragmentation techniques in both native and non-native top-down mass spectrometry. However, several competing reactions—primarily different forms of charge reduction—occur under ETD conditions, as evidenced by the distorted isotope patterns usually observed. In this work, we analyze these isotope patterns to compare the stability of nondissociative electron transfer (ETnoD) products, specifically noncovalent c/ z fragment complexes, across a range of ubiquitin conformational states. Using ion mobility, we find that more extended states are more prone to fragment release. We obtain evidence that for a given charge state, populations of ubiquitin ions formed either directly by electrospray ionization or through collapse of more extended states upon charge reduction, span a similar range of collision cross-sections. Products of gas-phase collapse are, however, less stabilized towards unfolding than the native conformation, indicating that the ions retain a memory of previous conformational states. Furthermore, this collapse of charge-reduced ions is promoted if the ions are `preheated' using collisional activation, with possible implications for the kinetics of gas-phase compaction.

Laser Plasma Instability (LPI) Driven Light Scattering Measurements with Nike KrF Laser

NASA Astrophysics Data System (ADS)

Oh, J.; Weaver, J. L.; Kehne, D. M.; Obenschain, S. P.; McLean, E. A.; Lehmberg, R. H.

2008-11-01

With the short wavelength (248 nm), large bandwidth (1˜2 THz), and ISI beam smoothing, Nike KrF laser is expected to have higher LPI thresholds than observed at other laser facilities. Previous measurements using the Nike laser [J. L. Weaver et al, Phys. Plasmas 14, 056316 (2007)] showed no LPI evidence from CH targets up to I˜2x10^15 W/cm^2. For further experiments to detect LPI excitation, Nike capabilities have been extended to achieve higher laser intensities by tighter beam focusing and higher power pulses. This talk will present results of a recent LPI experiment with the extended Nike capabilities focusing on light emission data in spectral ranges relevant to the Raman (SRS) and Two-Plasmon Decay (TPD) instabilities. The primary diagnostics were time-resolved spectrometers with an absolute-intensity-calibrated photodiode array in (0.4˜0.8)φ0 and a streak camera near 0.5φ0. The measurements were conducted at laser intensities of 10^15˜10^16 W/cm^2 on planar targets of CH solids and RF foams.

Personality and Academic Motivation: Replication, Extension, and Replication

ERIC Educational Resources Information Center

Jones, Martin H.; McMichael, Stephanie N.

2015-01-01

Previous work examines the relationships between personality traits and intrinsic/extrinsic motivation. We replicate and extend previous work to examine how personality may relate to achievement goals, efficacious beliefs, and mindset about intelligence. Approximately 200 undergraduates responded to the survey with a 150 participants replicating…

Open Group Transformations

NASA Astrophysics Data System (ADS)

Batalin, Igor; Marnelius, Robert

Open groups whose generators are in arbitrary involutions may be quantized within a ghost extended framework in terms of a nilpotent BFV-BRST charge operator. Previously we have shown that generalized quantum Maurer-Cartan equations for arbitrary open groups may be extracted from the quantum connection operators and that they also follow from a simple quantum master equation involving an extended nilpotent BFV-BRST charge and a master charge. Here we give further details of these results. In addition we establish the general structure of the solutions of the quantum master equation. We also construct an extended formulation whose properties are determined by the extended BRST charge in the master equation.

Extended-pulsed fidaxomicin versus vancomycin for Clostridium difficile infection in patients 60 years and older (EXTEND): a randomised, controlled, open-label, phase 3b/4 trial.

PubMed

Guery, Benoit; Menichetti, Francesco; Anttila, Veli-Jukka; Adomakoh, Nicholas; Aguado, Jose Maria; Bisnauthsing, Karen; Georgopali, Areti; Goldenberg, Simon D; Karas, Andreas; Kazeem, Gbenga; Longshaw, Chris; Palacios-Fabrega, Jose Alejandro; Cornely, Oliver A; Vehreschild, Maria J G T

2018-03-01

Clostridium difficile infection causes severe complications and frequently recurs. An extended-pulsed fidaxomicin regimen might facilitate sustained clinical cure by prolonging C difficile suppression and supporting gut microbiota recovery. We aimed to compare clinical outcomes of extended-pulsed fidaxomicin with standard vancomycin. In this randomised, controlled, open-label, superiority study, we recruited hospitalised adults aged 60 years and older with confirmed C difficile infection at 86 European hospitals. Patients were randomly assigned (1:1) using an interactive web response system to receive extended-pulsed fidaxomicin (200 mg oral tablets, twice daily on days 1-5, then once daily on alternate days on days 7-25) or vancomycin (125 mg oral capsules, four times daily on days 1-10), stratified by baseline C difficile infection severity, cancer presence, age (≥75 years vs <75 years), and number of previous C difficile infection occurrences. The primary endpoint was sustained clinical cure 30 days after end of treatment (day 55 for extended-pulsed fidaxomicin and day 40 for vancomycin), assessed in all randomised patients who met the inclusion criteria and received at least one dose of study medication (modified full analysis set). Adverse events were assessed in all patients who received at least one dose of study drug. The study is registered with ClinicalTrials.gov, number NCT02254967. Between Nov 6, 2014, and May 5, 2016, 364 patients were enrolled and randomly assigned to receive extended-pulsed fidaxomicin or vancomycin. 362 patients received at least one dose of study medication (181 in each group). 124 (70%) of 177 patients in the modified full analysis set receiving extended-pulsed fidaxomicin achieved sustained clinical cure 30 days after end of treatment, compared with 106 (59%) of 179 patients receiving vancomycin (difference 11% [95% CI 1·0-20·7], p=0·030; odds ratio 1·62 [95% CI 1·04-2·54]). Incidence of treatment-emergent adverse events did not differ between extended-pulsed fidaxomicin (121 [67%] of 181) and vancomycin (128 [71%] of 181) treatment arms. One death in the vancomycin arm was considered by the investigator to be related to study drug. Extended-pulsed fidaxomicin was superior to standard-dose vancomycin for sustained cure of C difficile infection, and, to our knowledge, extended-pulsed fidaxomicin recurrence rates in this study are the lowest observed in a randomised clinical trial of antibiotic treatment for C difficile infection. Astellas Pharma, Inc. Copyright © 2018 Elsevier Ltd. All rights reserved.

Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX

PubMed Central

Larsen, Charles E.; Alford, Dennis R.; Trautwein, Michael R.; Jalloh, Yanoh K.; Tarnacki, Jennifer L.; Kunnenkeri, Sushruta K.; Fici, Dolores A.; Yunis, Edmond J.; Awdeh, Zuheir L.; Alper, Chester A.

2014-01-01

We resequenced and phased 27 kb of DNA within 580 kb of the MHC class II region in 158 population chromosomes, most of which were conserved extended haplotypes (CEHs) of European descent or contained their centromeric fragments. We determined the single nucleotide polymorphism and deletion-insertion polymorphism alleles of the dominant sequences from HLA-DQA2 to DAXX for these CEHs. Nine of 13 CEHs remained sufficiently intact to possess a dominant sequence extending at least to DAXX, 230 kb centromeric to HLA-DPB1. We identified the regions centromeric to HLA-DQB1 within which single instances of eight “common” European MHC haplotypes previously sequenced by the MHC Haplotype Project (MHP) were representative of those dominant CEH sequences. Only two MHP haplotypes had a dominant CEH sequence throughout the centromeric and extended class II region and one MHP haplotype did not represent a known European CEH anywhere in the region. We identified the centromeric recombination transition points of other MHP sequences from CEH representation to non-representation. Several CEH pairs or groups shared sequence identity in small blocks but had significantly different (although still conserved for each separate CEH) sequences in surrounding regions. These patterns partly explain strong calculated linkage disequilibrium over only short (tens to hundreds of kilobases) distances in the context of a finite number of observed megabase-length CEHs comprising half a population's haplotypes. Our results provide a clearer picture of European CEH class II allelic structure and population haplotype architecture, improved regional CEH markers, and raise questions concerning regional recombination hotspots. PMID:25299700

ON THE RETRIEVAL OF MESOSPHERIC WINDS ON MARS AND VENUS FROM GROUND-BASED OBSERVATIONS AT 10 μm

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lopez-Valverde, M. A.; Montabone, L.; Sornig, M.

A detailed analysis is presented of ground-based observations of atmospheric emissions on Mars and Venus under non-local thermodynamic equilibrium (non-LTE) conditions at high spectral resolution. Our first goal is to comprehend the difficulties behind the derivation of wind speeds from ground-based observations. A second goal is to set a framework to permit comparisons with other observations and with atmospheric models. A forward model including non-LTE radiative transfer is used to evaluate the information content within the telescopic beam, and is later convolved with the beam function and a typical wind field to discern the major contributions to the measured radiance,more » including limb and nadir views. The emission mostly arises from the non-LTE limb around altitudes of 75 km on Mars and 110 km on Venus. We propose a parameterization of the limb emission using few geophysical parameters which can be extended to other hypothetical CO{sub 2} planetary atmospheres. The tropospheric or LTE component of the emission varies with the temperature and is important at low solar illumination but only for the emerging radiance, not for the wind determinations since these are derived from the Doppler shift at the non-LTE line cores. We evaluated the sources of uncertainty and found that the forward model errors amount to approximately 12% of the measured winds, which is normally smaller than the instrumental errors. We applied this study to revise a set of measurements extending for three Martian years and confirmed previous results suggesting winds that are too large simulated by current Martian circulation models at equatorial latitudes during solstice. We encourage new observational campaigns, particularly for the strong jet at mid–high latitudes on Mars, and propose general guidelines and recommendations for future observations.« less

Massive Open Online Course Completion Rates Revisited: Assessment, Length and Attrition

ERIC Educational Resources Information Center

Jordan, Katy

2015-01-01

This analysis is based upon enrolment and completion data collected for a total of 221 Massive Open Online Courses (MOOCs). It extends previously reported work (Jordan, 2014) with an expanded dataset; the original work is extended to include a multiple regression analysis of factors that affect completion rates and analysis of attrition rates…

Using the Extended Parallel Process Model to Examine Teachers' Likelihood of Intervening in Bullying

ERIC Educational Resources Information Center

Duong, Jeffrey; Bradshaw, Catherine P.

2013-01-01

Background: Teachers play a critical role in protecting students from harm in schools, but little is known about their attitudes toward addressing problems like bullying. Previous studies have rarely used theoretical frameworks, making it difficult to advance this area of research. Using the Extended Parallel Process Model (EPPM), we examined the…

A parametric study of the drift-tearing mode using an extended-magnetohydrodynamic model

DOE PAGES

King, Jacob R.; Kruger, S. E.

2014-10-24

The linear, collisional, constant-ψ drift-tearing mode is analyzed for different regimes of the plasma-β, ion-skin-depth parameter space with an unreduced, extended-magnetohydrodynamic model. Here, new dispersion relations are found at moderate plasma β and previous drift-tearing results are classified as applicable at small plasma β.

Extending Data Worth Analyses to Select Multiple Observations Targeting Multiple Forecasts.

PubMed

Vilhelmsen, Troels N; Ferré, Ty P A

2018-05-01

Hydrological models are often set up to provide specific forecasts of interest. Owing to the inherent uncertainty in data used to derive model structure and used to constrain parameter variations, the model forecasts will be uncertain. Additional data collection is often performed to minimize this forecast uncertainty. Given our common financial restrictions, it is critical that we identify data with maximal information content with respect to forecast of interest. In practice, this often devolves to qualitative decisions based on expert opinion. However, there is no assurance that this will lead to optimal design, especially for complex hydrogeological problems. Specifically, these complexities include considerations of multiple forecasts, shared information among potential observations, information content of existing data, and the assumptions and simplifications underlying model construction. In the present study, we extend previous data worth analyses to include: simultaneous selection of multiple new measurements and consideration of multiple forecasts of interest. We show how the suggested approach can be used to optimize data collection. This can be used in a manner that suggests specific measurement sets or that produces probability maps indicating areas likely to be informative for specific forecasts. Moreover, we provide examples documenting that sequential measurement election approaches often lead to suboptimal designs and that estimates of data covariance should be included when selecting future measurement sets. © 2017, National Ground Water Association.

The DES Bright Arcs Survey: Hundreds of Candidate Strongly Lensed Galaxy Systems from the Dark Energy Survey Science Verification and Year 1 Observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diehl, H. T.; Buckley-Geer, E. J.; Lindgren, K. A.

We report the results of searches for strong gravitational lens systems in the Dark Energy Survey (DES) Science Verification and Year 1 observations. The Science Verification data span approximately 250 sq. deg. with a median i -band limiting magnitude for extended objects (10 σ ) of 23.0. The Year 1 data span approximately 2000 sq. deg. and have an i -band limiting magnitude for extended objects (10 σ ) of 22.9. As these data sets are both wide and deep, they are particularly useful for identifying strong gravitational lens candidates. Potential strong gravitational lens candidate systems were initially identified basedmore » on a color and magnitude selection in the DES object catalogs or because the system is at the location of a previously identified galaxy cluster. Cutout images of potential candidates were then visually scanned using an object viewer and numerically ranked according to whether or not we judged them to be likely strong gravitational lens systems. Having scanned nearly 400,000 cutouts, we present 374 candidate strong lens systems, of which 348 are identified for the first time. We provide the R.A. and decl., the magnitudes and photometric properties of the lens and source objects, and the distance (radius) of the source(s) from the lens center for each system.« less

Observations of the giant radio lobes region of Centaurus A with SAS 3

NASA Technical Reports Server (NTRS)

Marshall, F. J.; Clark, G. W.

1981-01-01

Observations of the X-ray flux from the extended radio lobes of the galaxy Centaurus A obtained with the SAS 3 observatory are reported. The 15 x 15 deg region that includes the lobes was mapped by superposing data from raster scans with the horizontal tubular collimator detectors, which have a 1.7 deg FWHM circular field of view. Data obtained is consistent with the presence of superposed emission from the point sources NGC 5128 and MX 1312-42, a previously unreported source detected by the Einstein Observatory IPC. Fluxes of 4.63 + or - 0.14 x 10 to the -10th and 4.6 + or - 0.6 x 10 to the -11th ergs/sq cm per sec were measured for NGC 5128 and MX 1312-42, respectively, with best fit power law spectra of indices 0.83 + or - 0.04 and 0.62 + or - 0.10 and hydrogen column densities of 1.23 + or - 0.10 x 10 to the 23rd and 9.7 + or - 15.0 x 10 to the 21st atoms/sq cm. Results imply an upper limit of 2.9 x 10 to the 11th for the X-ray emission from the extended radio lobes of Cen A between 2 and 10 keV, which indicates a lower limit to the magnetic field in the lobes of 1.6 x 10 to the -6th gauss.

Detection of Extended Spectrum Beta-Lactamases Resistance Genes among Bacteria Isolated from Selected Drinking Water Distribution Channels in Southwestern Nigeria.

PubMed

Adesoji, Ayodele T; Ogunjobi, Adeniyi A

2016-01-01

Extended Spectrum Beta-Lactamases (ESBL) provide high level resistance to beta-lactam antibiotics among bacteria. In this study, previously described multidrug resistant bacteria from raw, treated, and municipal taps of DWDS from selected dams in southwestern Nigeria were assessed for the presence of ESBL resistance genes which include bla TEM, bla SHV, and bla CTX by PCR amplification. A total of 164 bacteria spread across treated (33), raw (66), and municipal taps (68), belonging to α-Proteobacteria, β-Proteobacteria, γ-Proteobacteria, Flavobacteriia, Bacilli, and Actinobacteria group, were selected for this study. Among these bacteria, the most commonly observed resistance was for ampicillin and amoxicillin/clavulanic acid (61 isolates). Sixty-one isolates carried at least one of the targeted ESBL genes with bla TEM being the most abundant (50/61) and bla CTX being detected least (3/61). Klebsiella was the most frequently identified genus (18.03%) to harbour ESBL gene followed by Proteus (14.75%). Moreover, combinations of two ESBL genes, bla SHV + bla TEM or bla CTX + bla TEM, were observed in 11 and 1 isolate, respectively. In conclusion, classic bla TEM ESBL gene was present in multiple bacterial strains that were isolated from DWDS sources in Nigeria. These environments may serve as foci exchange of genetic traits in a diversity of Gram-negative bacteria.

Ball lightning from atmospheric discharges via metal nanosphere oxidation: from soils, wood or metals.

PubMed

Abrahamson, John

2002-01-15

The slow (diffusion-limited) oxidation of metal nanoparticles has previously been proposed as the mechanism for ball lightning energy release, and argued to be the result of a normal lightning strike on soil. Here this basic model of networked nanoparticles is detailed further, and extended to lightning strikes on metal structures, and also to the action of other storm-related discharges or man-made discharges. The basic model predicted the important properties of "average" observed ball lightning, and the extension in this paper also covers high-energy examples of ball lightning. Laboratory checks of the theory are described, and predictions given of what conditions are necessary for observing ball lightning in the laboratory. Key requirements of the model are a sheltered region near the strike foot and starting materials which can generate a metal vapour under intensive heating, including soil, wood or a metal structure. The evolution of hydrocarbons (often plastics) along with metal vapour can ensure the local survival of the metal vapour even in an oxidizing atmosphere. Subsequent condensation of this vapour to metallic nanoparticles in networks provides the coherence of a ball structure, which also releases light over an extended time. Also discussed is the passage of ball lightning through a sheet of building material, including glass, and its occasional charring of flesh on close contact.

The Heavy Ion Afternoon Bulge: Structure and Formation Mechanisms

NASA Astrophysics Data System (ADS)

Fernandes, P. A.; Larsen, B.; Skoug, R. M.; Reeves, G. D.; Denton, M.; Engel, M.; Ferradas, C.; Funsten, H. O.; Henderson, M. G.; Jahn, J. M.; Morley, S.; Thomsen, M. F.

2017-12-01

Recent observations of near-equatorial inner magnetosphere plasma composition indicate the presence of an "afternoon bulge" plasma population at low L-shell. A detailed statistical survey using HOPE data characterized this afternoon bulge as an enhancement in 10 keV O+ and He+ ions extending from 1100-2200 MLT and 2 ≤ L ≤ 4 during quiet/moderate geomagnetic activity (Kp < 5). This statistical HOPE study postulated that formation of the bulge is caused by variations in Kp: 10 keV particles have access to low L-shells during geomagnetically active times and become trapped during the transition to quiet times. In this study, we expand on previous observations of the afternoon bulge by examining individual transits of this feature by the Van Allen Probes. We analyze periods with optimal spacecraft transits of the afternoon bulge region, including: May - Oct. 2013, Feb. - June 2014, and Apr. - Aug. 2015. We determine the presence and duration of the bulge during case studies representing three categories of geomagnetic activity: 1) extended quiet geomagnetic conditions; 2) sharp transitions of Kp from active to quiet conditions; and 3) rises and falls in Kp on the time scales of spacecraft orbits to days. We thoroughly characterize the energy structure of the bulge as a function of Kp. We also analyze these transits of the bulge in the context of plasma access using both drift path modeling and UBK-derived energy access maps.

The DES Bright Arcs Survey: Hundreds of Candidate Strongly Lensed Galaxy Systems from the Dark Energy Survey Science Verification and Year 1 Observations

NASA Astrophysics Data System (ADS)

Diehl, H. T.; Buckley-Geer, E. J.; Lindgren, K. A.; Nord, B.; Gaitsch, H.; Gaitsch, S.; Lin, H.; Allam, S.; Collett, T. E.; Furlanetto, C.; Gill, M. S. S.; More, A.; Nightingale, J.; Odden, C.; Pellico, A.; Tucker, D. L.; da Costa, L. N.; Fausti Neto, A.; Kuropatkin, N.; Soares-Santos, M.; Welch, B.; Zhang, Y.; Frieman, J. A.; Abdalla, F. B.; Annis, J.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Burke, D. L.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Cunha, C. E.; D'Andrea, C. B.; Desai, S.; Dietrich, J. P.; Drlica-Wagner, A.; Evrard, A. E.; Finley, D. A.; Flaugher, B.; García-Bellido, J.; Gerdes, D. W.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gschwend, J.; Gutierrez, G.; James, D. J.; Kuehn, K.; Kuhlmann, S.; Lahav, O.; Li, T. S.; Lima, M.; Maia, M. A. G.; Marshall, J. L.; Menanteau, F.; Miquel, R.; Nichol, R. C.; Nugent, P.; Ogando, R. L. C.; Plazas, A. A.; Reil, K.; Romer, A. K.; Sako, M.; Sanchez, E.; Santiago, B.; Scarpine, V.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Sheldon, E.; Smith, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Walker, A. R.; DES Collaboration

2017-09-01

We report the results of searches for strong gravitational lens systems in the Dark Energy Survey (DES) Science Verification and Year 1 observations. The Science Verification data span approximately 250 sq. deg. with a median I-band limiting magnitude for extended objects (10σ) of 23.0. The Year 1 data span approximately 2000 sq. deg. and have an I-band limiting magnitude for extended objects (10σ) of 22.9. As these data sets are both wide and deep, they are particularly useful for identifying strong gravitational lens candidates. Potential strong gravitational lens candidate systems were initially identified based on a color and magnitude selection in the DES object catalogs or because the system is at the location of a previously identified galaxy cluster. Cutout images of potential candidates were then visually scanned using an object viewer and numerically ranked according to whether or not we judged them to be likely strong gravitational lens systems. Having scanned nearly 400,000 cutouts, we present 374 candidate strong lens systems, of which 348 are identified for the first time. We provide the R.A. and decl., the magnitudes and photometric properties of the lens and source objects, and the distance (radius) of the source(s) from the lens center for each system.

Structural Identifiability of Dynamic Systems Biology Models

PubMed Central

Villaverde, Alejandro F.

2016-01-01

A powerful way of gaining insight into biological systems is by creating a nonlinear differential equation model, which usually contains many unknown parameters. Such a model is called structurally identifiable if it is possible to determine the values of its parameters from measurements of the model outputs. Structural identifiability is a prerequisite for parameter estimation, and should be assessed before exploiting a model. However, this analysis is seldom performed due to the high computational cost involved in the necessary symbolic calculations, which quickly becomes prohibitive as the problem size increases. In this paper we show how to analyse the structural identifiability of a very general class of nonlinear models by extending methods originally developed for studying observability. We present results about models whose identifiability had not been previously determined, report unidentifiabilities that had not been found before, and show how to modify those unidentifiable models to make them identifiable. This method helps prevent problems caused by lack of identifiability analysis, which can compromise the success of tasks such as experiment design, parameter estimation, and model-based optimization. The procedure is called STRIKE-GOLDD (STRuctural Identifiability taKen as Extended-Generalized Observability with Lie Derivatives and Decomposition), and it is implemented in a MATLAB toolbox which is available as open source software. The broad applicability of this approach facilitates the analysis of the increasingly complex models used in systems biology and other areas. PMID:27792726

Meditation leads to reduced default mode network activity beyond an active task

PubMed Central

Garrison, Kathleen A.; Zeffiro, Thomas A.; Scheinost, Dustin; Constable, R. Todd; Brewer, Judson A.

2015-01-01

Meditation has been associated with relatively reduced activity in the default mode network, a brain network implicated in self-related thinking and mind wandering. However, previous imaging studies have typically compared meditation to rest despite other studies reporting differences in brain activation patterns between meditators and controls at rest. Moreover, rest is associated with a range of brain activation patterns across individuals that has only recently begun to be better characterized. Therefore, this study compared meditation to another active cognitive task, both to replicate findings that meditation is associated with relatively reduced default mode network activity, and to extend these findings by testing whether default mode activity was reduced during meditation beyond the typical reductions observed during effortful tasks. In addition, prior studies have used small groups, whereas the current study tested these hypotheses in a larger group. Results indicate that meditation is associated with reduced activations in the default mode network relative to an active task in meditators compared to controls. Regions of the default mode showing a group by task interaction include the posterior cingulate/precuneus and anterior cingulate cortex. These findings replicate and extend prior work indicating that suppression of default mode processing may represent a central neural process in long-term meditation, and suggest that meditation leads to relatively reduced default mode processing beyond that observed during another active cognitive task. PMID:25904238

Formulation of cosmic-ray solar daily variation and its seasonal variation, produced from generalized stationary anisotropy of solar origin

NASA Technical Reports Server (NTRS)

Tatsuoka, R.; Nagashima, K.

1985-01-01

In previous papers, a formulation was presented of cosmic ray daily variations produced from solar anisotropies stationary through a year, and also of their annual (or seasonal) modulation caused by the annual variation of the rotation axis of the Earth relative to that of the Sun. These anisotropies are symmetric for an arbitrary rotation around an axis. From observations of the tri-diurnal variation, it has been suggested that solar anisotropies also contain some axis-asymmetric term of the third order with respect to the IMF-axis. This suggestion has recently found support in a theoretical study by Munakata and Nagashima. According to their results, the terms of axis-asymmetry with respect to IMF-axis appear also in the 2nd order anisotropy, together with some different kinds of axis-symmetric terms. The contribution of these anisotropies to the daily variation is different from that of those discussed previously. The above mentioned formulation is extended to a case of a generalized anisotropy.