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Sample records for extended skyrme interaction

  1. Extended Skyrme interactions for nuclear matter, finite nuclei, and neutron stars

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen; Chen, Lie-Wen

    2016-12-01

    Recent progress in theory, experiment, and observation challenges the mean-field models by using the conventional Skyrme interaction, suggesting that the extension of the conventional Skyrme interaction is necessary. In this work, by fitting the experimental data of a number of finite nuclei together with a few additional constraints on nuclear matter using the simulated annealing method, we construct three Skyrme interaction parameter sets; namely, eMSL07, eMSL08, and eMSL09, based on an extended Skyrme interaction which includes additional momentum and density-dependent two-body forces to effectively simulate the momentum dependence of the three-body force. The three new interactions (i) can reasonably describe the ground-state properties and the isoscalar giant monopole resonance energies of various spherical nuclei used in the fit as well as the ground-state properties of many other spherical nuclei, (ii) nicely conform to the current knowledge on the equation of state of asymmetric nuclear matter, (iii) eliminate the notorious unphysical instabilities of symmetric nuclear matter and pure neutron matter up to a very high density of 1.2 fm-3 , and (iv) simultaneously support heavier neutron stars with mass larger than two times the solar mass. One important difference of the three new interactions involves the prediction of the symmetry energy at supra-saturation densities, and these new interactions are thus potentially useful for the future determination of the largely uncertain high-density symmetry energy. In addition, the predictions of nuclear matter, finite nuclei, and neutron stars made using the three new interactions are compared with those made using the three typical interactions BSk22, BSk24, and BSk26 from the Brussels group.

  2. Breathing mode in the extended Skyrme model

    SciTech Connect

    Abada, A.; Merabet, H. )

    1993-09-01

    We study an extended Skyrme model which includes fourth- and sixth-order terms. We explore some static properties such as the [Delta]-nucleon mass splitting and investigate the Skyrmion breathing mode in the framework of the linear response theory. We find that the monopole response function has a pronounced peak located at [similar to]400 MeV, which we identify as the Roper resonance [ital N](1440). As compared to the standard one, the extended Skyrme model provides a more accurate description of baryon properties.

  3. Constraining the surface properties of effective Skyrme interactions

    NASA Astrophysics Data System (ADS)

    Jodon, R.; Bender, M.; Bennaceur, K.; Meyer, J.

    2016-08-01

    Background: Deformation energy surfaces map how the total binding energy of a nuclear system depends on the geometrical properties of intrinsic configurations, thereby providing a powerful tool to interpret nuclear spectroscopy and large-amplitude collective-motion phenomena such as fission. The global behavior of the deformation energy is known to be directly connected to the surface properties of the effective interaction used for its calculation. Purpose: The precise control of surface properties during the parameter adjustment of an effective interaction is key to obtain a reliable and predictive description of nuclear properties. The most relevant indicator is the surface-energy coefficient asurf. There are several possibilities for its definition and estimation, which are not fully equivalent and require a computational effort that can differ by orders of magnitude. The purpose of this study is threefold: first, to identify a scheme for the determination of asurf that offers the best compromise between robustness, precision, and numerical efficiency; second, to analyze the correlation between values for asurf and the characteristic energies of the fission barrier of 240Pu; and third, to lay out an efficient and robust procedure for how the deformation properties of the Skyrme energy density functional (EDF) can be constrained during the parameter fit. Methods: There are several frequently used possibilities to define and calculate the surface energy coefficient asurf of effective interactions built for the purpose of self-consistent mean-field calculations. The most direct access is provided by the model system of semi-infinite nuclear matter, but asurf can also be extracted from the systematics of binding energies of finite nuclei. Calculations can be carried out either self-consistently [Hartree-Fock (HF)], which incorporates quantal shell effects, or in one of the semiclassical extended Thomas-Fermi (ETF) or modified Thomas-Fermi (MTF) approximations. The

  4. Isovector response function of hot nuclear matter with Skyrme interactions

    SciTech Connect

    Braghin, F.L.; Vautherin, D.; Abada, A.

    1995-11-01

    We investigate the role of the effective nucleon-nucleon interaction in the description of giant dipole resonances in hot nuclei. For this purpose we calculate the response function of hot nuclear matter to a small isovector external perturbation using various effective Skyrme interactions. We find that for Skyrme forces with an effective mass close to unity an undamped zero sound mode occurs at zero temperature. This mode gives rise in finite nuclei (calculated via the Steinwedel-Jenssen model) to a resonance whose energy agrees with the observed value. We find that zero sound disappears at a temperature of a few MeV, leaving only a broad peak in the dipole strength. For Skyrme forces with a small value of the effective mass (0.4), there is no zero sound at zero temperature but only a weak peak located too high in energy. The strength distribution in this case is nearly independent of temperature and shows small collective effects. The relevance of these results for the saturation of photon multiplicities observed in recent experiments is pointed out.

  5. Speed of sound in nuclear matter and Skyrme effective interactions

    SciTech Connect

    Su, R.K.; Kuo, T.T.S.

    1987-02-01

    Using a nuclear equation of state derived from a finite-temperature Green's function method and the Skyrme effective interactions SkI, SkIII and SkM*, the authors have calculated the speed of sound in symmetric nuclear matter. For certain densities and temperatures, this speed is found to become super-luminous. Causal boundaries in the density-temperature plane are determined, and they indicate that SkM* is a more desirable effective interaction than SkI and SkIII. Comparison with a similar calculation by Osnes and Strottman is made.

  6. Exploring the extended density-dependent Skyrme effective forces for normal and isospin-rich nuclei to neutron stars

    SciTech Connect

    Agrawal, B.K.; Dhiman, Shashi K.; Kumar, Raj

    2006-03-15

    We parametrize the recently proposed generalized Skyrme effective force (GSEF) containing extended density dependence. The parameters of the GSEF are determined by the fit to several properties of the normal and isospin-rich nuclei. We also include in our fit a realistic equation of state for the pure neutron matter up to high densities so that the resulting Skyrme parameters can be suitably used to model the neutron star with the 'canonical' mass ({approx}1.4M{sub {center_dot}}). For the appropriate comparison, we generate a parameter set for the standard Skyrme effective force (SSEF) using exactly the same set data as employed to determine the parameters of the GSEF. We find that the GSEF yields larger values for the neutron skin thickness which are closer to the recent predictions based on the isospin diffusion data. The Skyrme parameters so obtained are employed to compute the strength function for the isoscalar giant monopole, dipole, and quadrupole resonances. It is found that in the case of GSEF, because of the larger value of the nucleon effective mass, the values of centroid energies for the isoscalar giant resonances are in better agreement with the corresponding experimental data than those obtained using the SSEF. We also present results for some of the key properties associated with the neutron star of canonical mass and for the one with the maximum mass.

  7. New parametrization of Skyrme's interaction for regularized multireference energy density functional calculations

    NASA Astrophysics Data System (ADS)

    Washiyama, K.; Bennaceur, K.; Avez, B.; Bender, M.; Heenen, P.-H.; Hellemans, V.

    2012-11-01

    Background: Symmetry restoration and configuration mixing in the spirit of the generator coordinate method based on energy density functionals have become widely used techniques in low-energy nuclear structure physics. Recently, it has been pointed out that these techniques are ill defined for standard Skyrme functionals, and a regularization procedure has been proposed to remove the resulting spuriosities from such calculations. This procedure imposes an integer power of the density for the density-dependent terms of the functional. At present, only dated parametrizations of the Skyrme interaction fulfill this condition.Purpose: To construct a set of parametrizations of the Skyrme energy density functional for multireference energy density functional calculations with regularization using the state-of-the-art fitting protocols.Method: The parametrizations were adjusted to reproduce ground-state properties of a selected set of doubly magic nuclei and properties of nuclear matter. Subsequently, these parameter sets were validated against properties of spherical and deformed nuclei.Results: Our parameter sets successfully reproduce the experimental binding energies and charge radii for a wide range of singly magic nuclei. Compared to the widely used SLy5 and to the SIII parametrization that has integer powers of the density, a significant improvement of the reproduction of the data is observed. Similarly, a good description of the deformation properties at A˜80 was obtained.Conclusions: We have constructed new Skyrme parametrizations with integer powers of the density and validated them against a broad set of experimental data for spherical and deformed nuclei. These parametrizations are tailor-made for regularized multireference energy density functional calculations and can be used to study correlations beyond the mean field in atomic nuclei.

  8. Kaon-Nucleon systems and their interactions in the Skyrme model

    NASA Astrophysics Data System (ADS)

    Ezoe, Takashi; Hosaka, Atsushi

    2016-08-01

    We study kaon-nucleon systems in the Skyrme model in a method based on the bound state approach of Callan-Klebanov but with the kaon around the physical nucleon of the rotating hedgehog. This corresponds to the variation after projection, reversing the order of semiclassical quantization of 1 /Nc expansion. The method, however, is considered to be suited to the study of weakly interacting kaon-nucleon systems including loosely K ¯N bound states such as Λ (1405 ). We have found a bound state with binding energy of order 10 MeV, consistent with the observed state. We also discuss the K ¯N interaction and find that it consists of an attraction in the middle range and a repulsion in the short range.

  9. α -decay spectra of odd nuclei using the effective Skyrme interaction

    NASA Astrophysics Data System (ADS)

    Ward, D. E.; Carlsson, B. G.; Åberg, S.

    2015-07-01

    Background: For nuclei heavier than 208Pb α decay is a dominating decay mode. α decay of odd nuclei can give spectroscopic information because different states in the daughter nucleus can be populated in the decay. Purpose: To explore and test microscopic descriptions of α decay of odd nuclei based on self-consistent models with effective nuclear interactions. To predict the hindrance of α decay of odd-A superheavy nuclei. Methods: We apply the method of our previous work [15e D. E. Ward, B. G. Carlsson, and S. Åberg, Phys. Rev. C 88, 064316 (2013), 10.1103/PhysRevC.88.064316] to the case of odd-A near-spherical nuclei. The Skyrme effective interaction SLy4 is used. Starting from the obtained Hartree-Fock-Bogoliubov vacuum and quasiparticle excitations, the α -particle formation amplitude is calculated giving the decay rates and hindrance of different α -decay channels. Result: The calculated relative decay rates show good agreement with available data. The hindrance of decay channels where the odd nucleon changes orbital is reasonably described by the microscopic calculation. Several hindered ground-state decays of superheavy nuclei are predicted, implying possible α -γ coincidences. Conclusions: The approach offers a practical method of making quantitative predictions for the relative hindrance of different α -decay channels.

  10. Stochastic approach to correlations beyond the mean field with the Skyrme interaction

    SciTech Connect

    Fukuoka, Y.; Nakatsukasa, T.; Funaki, Y.; Yabana, K.

    2012-10-20

    Large-scale calculation based on the multi-configuration Skyrme density functional theory is performed for the light N=Z even-even nucleus, {sup 12}C. Stochastic procedures and the imaginary-time evolution are utilized to prepare many Slater determinants. Each state is projected on eigenstates of parity and angular momentum. Then, performing the configuration mixing calculation with the Skyrme Hamiltonian, we obtain low-lying energy-eigenstates and their explicit wave functions. The generated wave functions are completely free from any assumption and symmetry restriction. Excitation spectra and transition probabilities are well reproduced, not only for the ground-state band, but for negative-parity excited states and the Hoyle state.

  11. Phase transitions of dense neutron matter with generalized Skyrme interaction to superfluid states with triplet pairing in strong magnetic field

    NASA Astrophysics Data System (ADS)

    Tarasov, A. N.

    2012-12-01

    A generalized non-relativistic Fermi-liquid approach was used to find analytical formulas for temperatures Tc1(n, H) and Tc2(n, H) (which are functions nonlinear of density n and linear of magnetic field H) of phase transitions in spatially uniform dense pure neutron matter from normal to superfluid states with spin-triplet p-wave pairing (similar to anisotropic superfluid phases 3He-A1 and 3He-A2) in steady and homogeneous strong magnetic field (but |μn| H ll Ec < ɛF(n), where μn is the magnetic dipole moment of a neutron, Ec is the cutoff energy and ɛF(n) is the Fermi energy in neutron matter). General formulas for Tc1, 2 (n, H) (valid for arbitrary parameterization of the effective Skyrme interaction in neutron matter) are specified here for generalized BSk18 parameterization of the Skyrme forces (with additional terms dependent on density n) on the interval 0.3 n0 < n < nc (BSk18) ≍ 2.7952 · n0, where n0 = 0.17 fm-3 is nuclear density and at critical density nc(BSk18) triplet superfluidity disappears, Tc0(n, cH = 0) = 0. Expressions for phase transition temperatures Tc0(n)<0.09MeV (at Ec = 10MeV) and Tc1, 2(n, H) are realistic non-monotone functions of density n for BSk18 parameterization of the Skyrme forces (contrary to their monotone increase for all previous BSk parameterizations). Phase transitions to superfluid states of such type might occur in liquid outer core of magnetars (strongly magnetized neutron stars).

  12. A New Open-Source Nuclear Equation of State Framework based on the Liquid-Drop Model with Skyrme Interactions

    NASA Astrophysics Data System (ADS)

    da Silva Schneider, Andre; Roberts, Luke; Ott, Christian

    2017-01-01

    The equation of state (EOS) of dense matter is an essential ingredient for numerical simulations of many astrophysical phenomena. We implement a modular open-source Fortran 90 code to construct the EOS of hot dense matter for astrophysical applications. For high density matter we use a non-relativistic liquid-drop description of nuclei that includes surface effects in a single nucleus approximation (SNA). The model is based on the work of Lattimer and Swesty and has been generalized to accommodate most Skyrme parametrizations available in the literature. Low density matter is described as an ensemble of nuclei in nuclear statistical equilibrium (NSE). The transition between the SNA and NSE regimes is performed via a continuous function that smoothly blends their Helmholtz free energy. To account for the existence of 2 solar mass neutron stars, we extend the formalism to allow for a stiffening of the EOS at densities above 3 times nuclear saturation density, where the properties of matter are presently poorly constrained. We study how different Skyrme parametrizations affect the EOS, neutron star mass-radius relationships, and the spherically symmetric collapse and post-bounce supernova evolution of massive stars.

  13. A New Open-Source Nuclear Equation of State Framework based on the Liquid-Drop Model with Skyrme Interactions

    NASA Astrophysics Data System (ADS)

    da Silva Schneider, Andre; Roberts, Luke F.; Ott, Christian D.

    2016-09-01

    The equation of state (EoS) of dense matter is an essential ingredient for numerical simulations of many astrophysical phenomena. We implement a modular open-source Fortran 90 code to construct EoS of hot dense matter for astrophysical applications. For high density matter we use a non-relativistic liquid-drop description of nuclei that includes surface effects in a single nucleus approximation (SNA). The model is based on the work of Lattimer and Swesty and has been generalized to accommodate most Skyrme parametrizations available in the literature. Low density matter is described as an ensemble of nuclei in nuclear statistical equilibrium (NSE). The transition between the two regimes is performed via a continuous function that smoothly blends their Helmholtz free energy. To account for the existence of 2 solar mass neutron stars, we extend the formalism to allow for a stiffening of the EoS at densities above 3 times nuclear saturation density, where the properties of matter are presently poorly constrained. We study how different Skyrme parametrizations affect the EoS, neutron star mass-radius relationships, and the spherically symmetric collapse and post-bounce supernova evolution of massive stars.

  14. Equation of state of hot polarized nuclear matter using the generalized Skyrme interaction

    NASA Astrophysics Data System (ADS)

    Abd-Alla, M.; Hager, S. A.

    2000-04-01

    We used the generalized Skyrme potential to study the equation of state of polarized nuclear matter in the frame of the Thomas-Fermi model. The critical temperature of the liquid-gas phase transition is found to be Tc=16.2 MeV. This critical temperature was found to decease with the asymmetry, spin, and spin-isospin excess parameters. The isothermal compressibility of polarized nuclear matter was also studied. The volume compressibility Kv was found to decrease with temperature. The symmetry compressibility Kx, the spin symmetry compressibility Ky, and the spin-isospin symmetry compressibility Kz were found to have a little increasing behavior with temperature.

  15. Shell evolution above Z ,N =50 within Skyrme density functional theory: The impact of deformation and tensor interactions

    NASA Astrophysics Data System (ADS)

    Shi, Yue

    2017-03-01

    Background: Recent years have seen considerable effort in associating the shell evolution (SE) for a chain of isotones or isotopes with the underlying nuclear interactions. In particular, it has been fairly well established that the tensor part of the Skyrme interaction is indispensable for understanding certain SE above Z ,N =50 shell closures, as a function of nucleon numbers. Purpose: The purpose of the present work is twofold: (1) to study the effect of deformation due to blocking on the SE above Z ,N =50 shell closures and (2) to examine the optimal parametrizations in the tensor part which gives a proper description of the SE above Z ,N =50 shell closures. Methods: I use the Skyrme-Hartree-Fock-Bogoliubov (SHFB) method to compute the even-even vacua of the Z =50 isotopes and N =50 isotones. For Sb and odd-A Sn isotopes, I perform calculations with a blocking procedure which accounts for the polarization effects, including deformations. Results: The blocking SHFB calculations show that the light odd-A Sb isotopes, with only one valence proton occupying down-sloping Ω =11 /2- and Ω =7 /2+ Nilsson orbits, assume finite oblate deformations. This reduces the energy differences between 11 /2- and 7 /2+ states by about 500 keV for 51Sb56 -66 , bringing the energy-difference curve closer to the experimental one. With une2t1 energy density functional (EDF), which differs from unedf2 parametrization by tensor terms, a better description of the slope of Δ e (π 1 h11 /2-π 1 g7 /2) as a function of neutron number has been obtained. However, the trend of Δ e (π 1 g7 /2-π 2 d5 /2) curve is worse using une2t1 EDF. Δ e (ν 3 s1 /2-ν 2 d5 /2) and Δ e (ν 1 g7 /2-ν 2 d5 /2) curve for N =50 isotones using une2t1 seems to be consistent with experimental data. The neutron SE of Δ e (ν 1 h11 /2-ν 1 g7 /2) and Δ e (ν 1 g7 /2-ν 2 d5 /2) for Sn isotopes are shown to be sensive to αT tensor parameter. Conclusions: Within the Skyrme self-consistent mean-field model

  16. Variation after parity projection calculation with the Skyrme interaction for light nuclei

    SciTech Connect

    Ohta, H.; Yabana, K.; Nakatsukasa, T.

    2004-07-01

    A self-consistent calculation with variation after parity projection is proposed to study both ground and excited states of light nuclei. This procedure provides description of the ground state incorporating some correlation effects, and self-consistent solutions for the excited states of negative parity. For flexible description of nuclear shapes, single particle orbitals are represented on a uniform grid in the three-dimensional Cartesian coordinates. The angular momentum projection is performed after variation to calculate rotational spectra. To demonstrate the usefulness of the method, results are shown for two N=Z nuclei, {sup 20}Ne and {sup 12}C, for which clustering correlations are known to be important. In the {sup 20}Ne nucleus, both cluster-like and shell-model-like states are described simultaneously in the present framework. For {sup 12}C nucleus, the appearance of three-alpha clustering correlation in the ground state is investigated in relation to the strength of the two-body spin-orbit interaction.

  17. Extended Thomas-Fermi density functionals in the presence of a tensor interaction in spherical symmetry

    SciTech Connect

    Bartel, J.; Bencheikh, K.; Meyer, J.

    2008-02-15

    For a one-body Hamiltonian obtained from the energy-density functional associated with a Skyrme effective interaction, including a tensor force, semiclassical functional densities are derived in the framework of the Extended Thomas-Fermi method, in spherical symmetry, for the kinetic energy and spin-orbit density. The structure of the self-consistent mean-field potentials constructed with such semiclassical functionals is studied. The impact of the tensor force in particular on the spin-orbit form factor clearly indicates the necessity of including such tensor-force terms in the theoretical description of atomic nuclei and their possible influence on the shell structure of exotic nuclei.

  18. The Skyrme Model in the BPS Limit

    NASA Astrophysics Data System (ADS)

    Adam, C.; Naya, C.; Sánchez-Guillén, J.; Vazquez, R.; Wereszczyński, A.

    In this review, we summarize the main features of the BPS Skyrme model which provides a physically well-motivated idealization of atomic nuclei and nuclear matter: (1) it leads to zero binding energies for classical solitons (while realistic binding energies emerge owing to the semiclassical corrections, the Coulomb interaction and isospin breaking); (2) it describes a perfect non-barotropic fluid already at the microscopic (field theoretical) level which allows to study thermodynamics beyond the mean-field limit. These properties allow for an approximate but analytical calculation of binding energies of the most abundant nuclei, for a determination of the equation of state of skyrmionic matter (both in the full field theory and in a mean-field approximation) as well as the description of neutron stars as Skyrme solitons with a very good agreement with available observational data. All these results suggest that the proper low energy effective model of QCD should be close to the BPS Skyrme model in a certain sense (a "near-BPS Skyrme model"), with a prominent role played by the BPS part.

  19. Wormholes in the Skyrme model

    SciTech Connect

    Iwazaki, A. )

    1990-05-15

    We present wormhole solutions in the Skyrme model coupled with gravity. The wormholes have topological numbers which are identical to those of Skyrmions; they are baryon numbers. We discuss the physical implications of the wormholes.

  20. Exact results in the Skyrme model in (3+1) dimensions via the generalized hedgehog ansatz

    NASA Astrophysics Data System (ADS)

    Canfora, Fabrizio

    2016-09-01

    We present exact results in the (3 + 1) -dimensional Skyrme model. First of all, it will be shown that, in the Pionic sector, a quite remarkable phenomenon for a non-integrable (3 + 1) -dimensional field theory appears: a non-linear superposition law is available allowing the composition of solutions in order to generate new solutions of the full field equations keeping alive, at the same time, the interactions terms in the energy-density. Secondly, it will be shown that the generalized hedgehog ansatz can be extended to suitable curved backgrounds. Interestingly, one can choose the background metric in such a way to describe finite-volume effects and, at the same time, to simplify the Skyrme field equations. In this way, it is possible to construct the first exact multi-Skyrmionic configurations of the (3 + 1) -dimensional Skyrme model with arbitrary high winding number and living at finite volume. Last but not least, a novel BPS bound (which is sharper than the usual one in term of the winding number) will be derived which can be saturated and reduces the field equations to a first-order equation for the profile.

  1. Bimodal Fission in the Skyrme-Hartree-Fock Approach

    SciTech Connect

    Staszczak, A.; Dobaczewski, J.; Nazarewicz, Witold

    2007-01-01

    Spontaneous fission properties of 256Fm, 258Fm, and 260Fm isotopes are studied within the Skyrme-Hartree-Fock+BCS framework. In the particle-hole channel we take the Skyrme SkM* effective force, while in the particle-particle channel we employ the seniority pairing interaction. Three static fission paths for all investigated heavy fermium isotopes are found. The analysis of these fission modes allows to describe observed asymmetric fission of 256Fm, as well as bimodal fission of 258Fm and symmetric fission in 260Fm.

  2. Skyrme forces and decay of the Rf266*104 nucleus synthesized via different incoming channels

    NASA Astrophysics Data System (ADS)

    Niyti, Deep, Aman; Kharab, Rajesh; Chopra, Sahila; Gupta, Raj K.

    2017-03-01

    The excitation functions for the production of 262Rf, 261Rf, and 260Rf isotopes via 4 n -, 5 n -, and 6 n -decay channels from the *266Rf compound nucleus are studied within the dynamical cluster-decay model (DCM), including deformations β2 i and so-called hot-optimum orientations θi which support symmetric fission, in agreement with experiments. The data are available for 18O+248Cm and 22Ne+244Pu reactions, respectively, at the energy ranges of Elab=88.2 to 101.3 and 109.0 to 124.8 MeV. For the nuclear interaction potentials, we use the Skyrme energy density functional (SEDF) based on semiclassical extended Thomas Fermi (ETF) approach, which means an extension of the earlier study of excitation functions of *266Rf formed in 18O+248Cm reaction, based on the DCM using the pocket formula for nuclear proximity potential, showing interaction dependence. The Skyrme forces used here are the old SIII and SIV and new GSkI and KDE0(v1) given for both normal and isospin-rich nuclei, with densities added in frozen density approximation. Interestingly, the DCM gives an excellent fit to the measured data on fusion evaporation residue (ER) for both the incoming channels (18O+248Cm and 22Ne+244Pu ) at the energy range Elab=88.2 to 124.8 MeV, independent of the entrance channel and Skyrme force used. The possible fusion-fission (ff) and quasifission (qf) mass regions of fragments on DCM are also predicted. The DCM with Skyrme forces is further used to look for all the possible target-projectile (t-p) combinations forming the cold compound nucleus (CN) *266Rf at the CN excitation energy of Elab for hot compact configurations. The fusion evaporation residue cross sections, for the proposed new reactions in synthesizing the CN *266Rf, are also estimated for the future experiments, and role of mass asymmetry of nuclei is indicated.

  3. Baby Skyrme models without a potential term

    NASA Astrophysics Data System (ADS)

    Ashcroft, Jennifer; Haberichter, Mareike; Krusch, Steffen

    2015-05-01

    We develop a one-parameter family of static baby Skyrme models that do not require a potential term to admit topological solitons. This is a novel property as the standard baby Skyrme model must contain a potential term in order to have stable soliton solutions, though the Skyrme model does not require this. Our new models satisfy an energy bound that is linear in terms of the topological charge and can be saturated in an extreme limit. They also satisfy a virial theorem that is shared by the Skyrme model. We calculate the solitons of our new models numerically and observe that their form depends significantly on the choice of parameter. In one extreme, we find compactons while at the other there is a scale invariant model in which solitons can be obtained exactly as solutions to a Bogomolny equation. We provide an initial investigation into these solitons and compare them with the baby Skyrmions of other models.

  4. Fission barriers for neutron-rich nuclei by means of Skyrme-Hartree-Fock-Bogoliubov calculation

    SciTech Connect

    Hashizume, K.; Wada, T.; Ohta, M.; Samyn, M.; Goriely, S.

    2007-02-26

    The nuclear fission barrier height has been estimated by means of the constraint Skyrme Hartree-Fock-Bogoliubov method. The potential energy surfaces obtained by the method are analyzed with the flooding method to find several saddle points. The results for U, Np, Bk isotopes are compared with the barrier derived from the extended Thomas-Fermi plus Strutinsky integral method.

  5. Topological solitons in the supersymmetric Skyrme model

    NASA Astrophysics Data System (ADS)

    Gudnason, Sven Bjarke; Nitta, Muneto; Sasaki, Shin

    2017-01-01

    A supersymmetric extension of the Skyrme model was obtained recently, which consists of only the Skyrme term in the Nambu-Goldstone (pion) sector complemented by the same number of quasi-Nambu-Goldstone bosons. Scherk-Schwarz dimensional reduction yields a kinetic term in three or lower dimensions and a potential term in two dimensions, preserving supersymmetry. Euclidean solitons (instantons) are constructed in the supersymmetric Skyrme model. In four dimensions, the soliton is an instanton first found by Speight. Scherk-Schwarz dimensional reduction is then performed once to get a 3-dimensional theory in which a 3d Skyrmion-instanton is found and then once more to get a 2d theory in which a 2d vortex-instanton is obtained. Although the last one is a global vortex it has finite action in contrast to conventional theory. All of them are non-BPS states breaking all supersymmetries.

  6. Extending theories on muon-specific interactions

    SciTech Connect

    Carlson, Carl E.; Freid, Michael C.

    2015-11-23

    The proton radius puzzle, the discrepancy between the proton radius measured in muonic hydrogen and electronic hydrogen, has yet to be resolved. There are suggestions that beyond the standard model (BSM) physics could resolve both this puzzle and the muon anomalous magnetic moment discrepancy. Karshenboim et al. point out that simple, nonrenormalizable, models in this direction involving new vector bosons have serious problems when confronting high energy data. The prime example is radiative corrections to W to μν decay which exceed experimental bounds. We show how embedding the model in a larger and arguably renormalizable theory restores gauge invariance of the vector particle interactions and controls the high energy behavior of decay and scattering amplitudes. Thus BSM explanations of the proton radius puzzle can still be viable.

  7. Extending theories on muon-specific interactions

    DOE PAGES

    Carlson, Carl E.; Freid, Michael C.

    2015-11-23

    The proton radius puzzle, the discrepancy between the proton radius measured in muonic hydrogen and electronic hydrogen, has yet to be resolved. There are suggestions that beyond the standard model (BSM) physics could resolve both this puzzle and the muon anomalous magnetic moment discrepancy. Karshenboim et al. point out that simple, nonrenormalizable, models in this direction involving new vector bosons have serious problems when confronting high energy data. The prime example is radiative corrections to W to μν decay which exceed experimental bounds. We show how embedding the model in a larger and arguably renormalizable theory restores gauge invariance ofmore » the vector particle interactions and controls the high energy behavior of decay and scattering amplitudes. Thus BSM explanations of the proton radius puzzle can still be viable.« less

  8. Exotic Baryon Resonances in the Skyrme Model

    NASA Astrophysics Data System (ADS)

    Diakonov, Dmitri; Petrov, Victor

    We outline how one can understand the Skyrme model from the modern perspective. We review the quantization of the SU(3) rotations of the Skyrmion, leading to the exotic baryons that cannot be made of three quarks. It is shown that in the limit of large number of colors the lowest-mass exotic baryons can be studied from the kaon-Skyrmion scattering amplitudes, an approach known after Callan and Klebanov. We follow this approach and find, both analytically and numerically, a strong Θ+ resonance in the scattering amplitude that is traced to the rotational mode. The Skyrme model does predict an exotic resonance Θ+ but grossly overestimates the width. To understand better the factors affecting the width, it is computed by several methods giving, however, identical results. In particular, we show that insofar as the width is small, it can be found from the transition axial constant. The physics leading to a narrow Θ+ resonance is briefly reviewed and affirmed.

  9. Properties of the Skyrme soliton configuration

    NASA Astrophysics Data System (ADS)

    Ananias Neto, Jorge; Galain, Ramón Méndez; Ferreira, Erasmo

    1991-07-01

    Properties of the Euler-Lagrange differential equation for cos F, where F is the chiral angle of the classical Skyrme soliton in the hedgehog ansatz, are investigated. The power series solution for y=cos F, is obtained that presents the behavior of an almost geometric series, and the existence of single poles located at imaginary values of the radial variable r is shown. Padé approximants are built to the series expansion about the origin, and its terms are modified in order to incorporate the main features of the asymptotic behavior of the field configuration. Thus rational fractions are constructed which provide very good and practical analytical representations of the Skyrme soliton profile function.

  10. Exact kink solitons in Skyrme crystals

    NASA Astrophysics Data System (ADS)

    Chen, Shouxin; Li, Yijun; Yang, Yisong

    2014-01-01

    We present an explicit integration of the kink soliton equation obtained in a recent interesting study of the classical Skyrme model where the field configurations are of a generalized hedgehog form which is of a domain-wall type. We also show that in such a reduced one-dimensional setting the first-order and second-order equations are equivalent. Consequently, in such a context, all finite-energy solitons are Bogomolnyi-Prasad-Sommerfield type and precisely known.

  11. Conservation laws in Skyrme-type models

    NASA Astrophysics Data System (ADS)

    Adam, C.; Sánchez-Guillén, J.; Wereszczyński, A.

    2007-03-01

    The zero curvature representation of Zakharov and Shabat [V. E. Zakharov and A. B. Shabat, Soviet Phys. JETP 34, 62 (1972)] has been generalized recently to higher dimensions and has been used to construct nonlinear field theories which are integrable or contain integrable submodels. The Skyrme model, for instance, contains an integrable subsector with infinitely many conserved currents, and the simplest Skyrmion with baryon number 1 belongs to this subsector. Here we use a related method, based on the geometry of target space, to construct a whole class of theories which are integrable or contain integrable subsectors (where integrability means the existence of infinitely many conservation laws). These models have three-dimensional target space, like the Skyrme model, and their infinitely many conserved currents turn out to be Noether currents of the volume-preserving diffeomorphisms on target space. Specifically for the Skyrme model, we find both weak and strong integrability conditions, where the conserved currents form a subset of the algebra of volume-preserving diffeomorphisms in both cases, but this subset is a subalgebra only for the weak integrable submodel.

  12. Compact and extended objects from self-interacting phantom fields

    NASA Astrophysics Data System (ADS)

    Dzhunushaliev, Vladimir; Folomeev, Vladimir; Makhmudov, Arislan; Urazalina, Ainur; Singleton, Douglas; Scott, John

    2016-07-01

    In this work, we investigate localized and extended objects for gravitating, self-interacting phantom fields. The phantom fields come from two scalar fields with a "wrong-sign" (negative) kinetic energy term in the Lagrangian. This study covers several solutions supported by these phantom fields: phantom balls, traversable wormholes, phantom cosmic strings, and "phantom" domain walls. These four systems are solved numerically, and we try to draw out general, interesting features in each case.

  13. Nuclear binding energies from a Bogomol'nyi-Prasad-Sommerfield Skyrme model

    NASA Astrophysics Data System (ADS)

    Adam, C.; Naya, C.; Sanchez-Guillen, J.; Wereszczynski, A.

    2013-11-01

    Recently, within the space of generalized Skyrme models, a submodel with a Bogomol'nyi-Prasad-Sommerfield (BPS) bound was identified that reproduces some bulk properties of nuclear matter already on a classical level and, as such, constitutes a promising field theory candidate for the detailed and reliable description of nuclei and hadrons. Here we extend and further develop these investigations by applying the model to the calculation of nuclear binding energies. Concretely, we calculate these binding energies by including the classical soliton energies, the excitation energies from the collective coordinate quantization of spin and isospin, the electrostatic Coulomb energies, and a small explicit isospin symmetry breaking, which accounts for the mass difference between proton and neutron. The integrability properties of the BPS Skyrme model allow, in fact, for an analytical calculation of all contributions, which may then be compared with the semi-empirical mass formula. We find that for heavier nuclei, where the model is expected to be more accurate on theoretical grounds, the resulting binding energies are already in excellent agreement with their physical values. This result provides further strong evidence for the viability of the BPS Skyrme model as a distinguished starting point and lowest-order approximation for the detailed quantitative investigation of nuclear and hadron physics.

  14. Skyrme tensor force in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Stevenson, P. D.; Suckling, E. B.; Fracasso, S.; Barton, M. C.; Umar, A. S.

    2016-05-01

    Background: It is generally acknowledged that the time-dependent Hartree-Fock (TDHF) method provides a useful foundation for a fully microscopic many-body theory of low-energy heavy ion reactions. The TDHF method is also known in nuclear physics in the small-amplitude domain, where it provides a useful description of collective states, and is based on the mean-field formalism, which has been a relatively successful approximation to the nuclear many-body problem. Currently, the TDHF theory is being widely used in the study of fusion excitation functions, fission, and deep-inelastic scattering of heavy mass systems, while providing a natural foundation for many other studies. Purpose: With the advancement of computational power it is now possible to undertake TDHF calculations without any symmetry assumptions and incorporate the major strides made by the nuclear structure community in improving the energy density functionals used in these calculations. In particular, time-odd and tensor terms in these functionals are naturally present during the dynamical evolution, while being absent or minimally important for most static calculations. The parameters of these terms are determined by the requirement of Galilean invariance or local gauge invariance but their significance for the reaction dynamics have not been fully studied. This work addresses this question with emphasis on the tensor force. Method: The full version of the Skyrme force, including terms arising only from the Skyrme tensor force, is applied to the study of collisions within a completely symmetry-unrestricted TDHF implementation. Results: We examine the effect on upper fusion thresholds with and without the tensor force terms and find an effect on the fusion threshold energy of the order several MeV. Details of the distribution of the energy within terms in the energy density functional are also discussed. Conclusions: Terms in the energy density functional linked to the tensor force can play a non

  15. Stability of quantized chiral soliton with the Skyrme term

    NASA Astrophysics Data System (ADS)

    Sawada, Shoji; Yang, Keyan

    1991-09-01

    Stability of the chiral soliton with the Skyrme term that is quantized by taking account of breathing modes in addition to the spin-isospin rotation is examined on the basis of a family of trial functions for the profile function of the hedgehog ansatz. It is shown that when the effects of the Skyrme term are sufficiently strong (small Skyrme term constant e), the eigenstates of lower spin-isospin are stable, having finite contributions both from the rotational and breathing modes. On the other hand when the effects of the Skyrme term are weak (e>5), the spin-isospin rotational and the breathing modes are completely frozen and all states tend to infinitely degenerate states labeled by the constant SU(2) matrices.

  16. Kantowski-Sachs universes sourced by a Skyrme fluid

    NASA Astrophysics Data System (ADS)

    Parisi, Luca; Radicella, Ninfa; Vilasi, Gaetano

    2015-03-01

    The Kantowski-Sachs cosmological model sourced by a Skyrme field and a cosmological constant is considered in the framework of general relativity. Assuming a constant radial profile function α =π /2 for the hedgehog ansatz, the Skyrme contribution to Einstein equations is shown to be equivalent to an anisotropic fluid. Using dynamical system techniques, a qualitative analysis of the cosmological equations is presented. Physically interesting features of the model such as isotropization, bounce and recollapse are discussed.

  17. Gauged baby Skyrme model with a Chern-Simons term

    NASA Astrophysics Data System (ADS)

    Samoilenka, A.; Shnir, Ya.

    2017-02-01

    The properties of the multisoliton solutions of the (2 +1 )-dimensional Maxwell-Chern-Simons-Skyrme model are investigated numerically. Coupling to the Chern-Simons term allows for existence of the electrically charge solitons which may also carry magnetic fluxes. Two particular choices of the potential term is considered: (i) the weakly bounded potential and (ii) the double vacuum potential. In the absence of gauge interaction in the former case the individual constituents of the multisoliton configuration are well separated, while in the latter case the rotational invariance of the configuration remains unbroken. It is shown that coupling of the planar multi-Skyrmions to the electric and magnetic field strongly affects the pattern of interaction between the constituents. We analyze the dependency of the structure of the solutions, the energies, angular momenta, electric and magnetic fields of the configurations on the gauge coupling constant g , and the electric potential. It is found that, generically, the coupling to the Chern-Simons term strongly affects the usual pattern of interaction between the skyrmions, in particular the electric repulsion between the solitons may break the multisoliton configuration into partons. We show that as the gauge coupling becomes strong, both the magnetic flux and the electric charge of the solutions become quantized although they are not topological numbers.

  18. Description of induced nuclear fission with Skyrme energy functionals. II. Finite temperature effects

    NASA Astrophysics Data System (ADS)

    Schunck, N.; Duke, D.; Carr, H.

    2015-03-01

    Understanding the mechanisms of induced nuclear fission for a broad range of neutron energies could help resolve fundamental science issues, such as the formation of elements in the universe, but could have also a large impact on societal applications in energy production or nuclear waste management. The goal of this paper is to set up the foundations of a microscopic theory to study the static aspects of induced fission as a function of the excitation energy of the incident neutron, from thermal to fast neutrons. To account for the high excitation energy of the compound nucleus, we employ a statistical approach based on finite temperature nuclear density functional theory with Skyrme energy densities, which we benchmark on the 239Pu(n ,f ) reaction. We compute the evolution of the least-energy fission pathway across multidimensional potential energy surfaces with up to five collective variables as a function of the nuclear temperature and predict the evolution of both the inner and the outer fission barriers as a function of the excitation energy of the compound nucleus. We show that the coupling to the continuum induced by the finite temperature is negligible in the range of neutron energies relevant for many applications of neutron-induced fission. We prove that the concept of quantum localization introduced recently can be extended to T >0 , and we apply the method to study the interaction energy and total kinetic energy of fission fragments as a function of the temperature for the most probable fission. While large uncertainties in theoretical modeling remain, we conclude that a finite temperature nuclear density functional may provide a useful framework to obtain accurate predictions of fission fragment properties.

  19. Metastability of solitons in a generalized Skyrme model

    NASA Astrophysics Data System (ADS)

    Pottinger, D. E. L.; Rathske, E.

    1986-04-01

    We consider soliton solutions in the generalized chirally symmetric Skyrme model which includes, in addition to the usual commutator term, a symmetric term of fourth order in the field derivatives. The classical energy of static hedgehog field configurations is determined numerically as a function of the angle characterizing the relative contribution of these two terms. Next to the Skyrme combination, we find a region where numerical solutions either are metastable (due to the energy being unbounded from below) or do not exist at all. We also study the exact quantization of the isorotational collective coordinates. Our conclusion is that, demanding consistency with meson phenomenology for the signs of the parameters, the model discussed in this paper can lead to reliable physical results only for small deviations from Skyrme's original stabilizing term.

  20. Extending Interactive Writing into Grades 2-5

    ERIC Educational Resources Information Center

    Roth, Kate; Dabrowski, Joan

    2014-01-01

    Interactive writing is an instructional practice widely considered effective and most appropriate for emergent writers. This article asserts that it is a valuable method for more fluent writers in grades 2-5. It outlines the basic lesson sequence and proposes four key shifts to adapt interactive writing for older, more fluent writers: 1) The…

  1. Genesis and evolution of the Skyrme model from 1954 to the present

    SciTech Connect

    San Yuk, V.I. . Dept. of Physics)

    1992-01-10

    Not widely known facts on the genesis of the Skyrme model are presented in a historical survey, based on Skyrme's earliest papers and on his own published remembrance. This paper considers the evolution of Skyrme's model description of nuclear matter from the Mesonic Fluid model up to its final version, known as the baryon model. We pay special tribute to some well-known ideas in contemporary particle physics which one can find in Skyrme's earlier papers, such as: Nuclear Democracy, the Solitonic Mechanism, the Nonlinear Realization of Chiral Symmetry, Topological Charges, Fermi-Bose Transmutations, etc. It is curious to note in the final version of the Skyrme model gleams of Kelvin's Vortex Atoms theory. In conclusion we make a brief analysis of the validity of Skyrme's conjectures in view of recent results and pinpoint some questions which still remain.

  2. Generalized Skyrme model with the loosely bound potential

    NASA Astrophysics Data System (ADS)

    Gudnason, Sven Bjarke; Zhang, Baiyang; Ma, Nana

    2016-12-01

    We study a generalization of the loosely bound Skyrme model which consists of the Skyrme model with a sixth-order derivative term—motivated by its fluidlike properties—and the second-order loosely bound potential—motivated by lowering the classical binding energies of higher-charged Skyrmions. We use the rational map approximation for the Skyrmion of topological charge B =4 , calculate the binding energy of the latter, and estimate the systematic error in using this approximation. In the parameter space that we can explore within the rational map approximation, we find classical binding energies as low as 1.8%, and once taking into account the contribution from spin-isospin quantization, we obtain binding energies as low as 5.3%. We also calculate the contribution from the sixth-order derivative term to the electric charge density and axial coupling.

  3. Exploration of a modified density dependence in the Skyrme functional

    SciTech Connect

    Erler, J.; Reinhard, P.-G.; Kluepfel, P.

    2010-10-15

    A variant of the basic Skyrme-Hartree-Fock functional is considered dealing with a new form of density dependence. It employs only integer powers and thus will allow a more sound basis for projection schemes (particle number, angular momentum). We optimize the new functional with exactly the same adjustment strategy as used in an earlier study with a standard Skyrme functional. This allows direct comparisons of the performance of the new functional relative to the standard one. We discuss various observables: bulk properties of finite nuclei, nuclear matter, giant resonances, superheavy elements, and energy systematics. The new functional performs at least as well as the standard one, but offers a wider range of applicability (e.g., for projection) and more flexibility in the regime of high densities.

  4. The spin-flip extended single excitation configuration interaction method

    NASA Astrophysics Data System (ADS)

    Casanova, David; Head-Gordon, Martin

    2008-08-01

    An extension of the spin-flip single excitation configuration interaction (SF-CIS) method is introduced. The extension, abbreviated as SF-XCIS, includes all configurations in which no more than one virtual level of the high spin triplet reference becomes occupied and no more than one doubly occupied level becomes vacant. The number of such configurations is quadratic with molecule size, and the method is implemented in a direct algorithm whose cost scales in the same way with molecule size as CIS itself, thus permitting applications to large systems. Starting from a spin restricted triplet determinant, SF-XCIS yields spin-pure singlet, triplet, and quintet states, and treats both half-occupied reference orbitals in a fully balanced way to allow application to strongly correlated problems. Tests on bond dissociation in the HF molecule, the torsional potential of ethylene, and excited states of polyenes show encouraging improvements using SF-XCIS compared to SF-CIS and a previously suggested extension, the spin-complete CIS model.

  5. The Analytical Parametrization of Fusion Barrier by Using the Skyrme Energy-Density Function Model

    NASA Astrophysics Data System (ADS)

    Zanganeh, V.; Mirzaei, M.; N., Wang

    2015-08-01

    Using the skyrme energy density formalism, a pocket formula is introduced for barrier heights and positions of 95 fusion reactions (48 ≤ ZP ZT ≤ 1520) with respect to the charge and mass numbers of the interacting nuclei. It is shown that the parameterized values of RB and VB are able to reproduce the corresponding experimental data with good accuracy. Moreover, the absolute errors of our formulas are less than those obtained using the analytical parametrization forms of the fusion barrier based on the proximity versions. The ability of the parameterized forms of the barrier heights and its positions to reproduce the experimental data of the fusion cross section have been analyzed using the Wong model.

  6. Rotational-vibrational coupling in the BPS Skyrme model of baryons

    NASA Astrophysics Data System (ADS)

    Adam, C.; Naya, C.; Sanchez-Guillen, J.; Wereszczynski, A.

    2013-11-01

    We calculate the rotational-vibrational spectrum in the BPS Skyrme model for the hedgehog skyrmion with baryon number one. The resulting excitation energies for the nucleon and delta Roper resonances are slightly above their experimental values. Together with the fact that in the standard Skyrme model these excitation energies are significantly lower than the experimental ones, this provides strong evidence for the conjecture that the inclusion of the BPS Skyrme model is required for a successful quantitative description of physical properties of baryons and nuclei.

  7. Extended dynamical mean-field study of the Hubbard model with long-range interactions

    NASA Astrophysics Data System (ADS)

    Huang, Li; Ayral, Thomas; Biermann, Silke; Werner, Philipp

    2014-11-01

    Using extended dynamical mean-field theory and its combination with the G W approximation, we compute the phase diagrams and local spectral functions of the single-band extended Hubbard model on the square and simple cubic lattices, considering long-range interactions up to the third nearest neighbors. The longer-range interactions shift the boundaries between the metallic, charge-ordered insulating, and Mott insulating phases, and lead to characteristic changes in the screening modes and local spectral functions. Momentum-dependent self-energy contributions enhance the correlation effects and thus compete with the additional screening effect from longer-range Coulomb interactions. Our results suggest that the influence of longer-range intersite interactions is significant, and that these effects deserve attention in realistic studies of correlated materials.

  8. Collective Inertia and Fission Barriers Within the Skyrme-Hartree-Fock Theory

    SciTech Connect

    Baran, A.; Staszczak, A.; Dobaczewski, J.; Nazarewicz, Witold

    2007-01-01

    Spontaneous fission barriers, quadrupole inertia tensor, and zero-point quadrupole correlation energy are calculated for 252,256,258Fm in the framework of the self-consistent Skyrme-Hartree-Fock+BCS theory. Two ways of computing collective inertia are employed: the Gaussian Overlap Approximation to the Generator Coordinate Method and cranking ansatz. The Skyrme results are compared with those of the Gogny-Hartree-Fock-Bogoliubov model.

  9. A new Skyrme energy density functional for a better description of spin-isospin resonances

    SciTech Connect

    Roca-Maza, X.; Colò, G.; Cao, Li-Gang; Sagawa, H.

    2015-10-15

    A correct determination of the isospin and spin-isospin properties of the nuclear effective interaction should lead to an accurate description of the Gamow-Teller resonance (GT), the Spin Dipole Resonance (SDR), the Giant Dipole Resonance (GDR) or the Antianalog Giant Dipole Resonance (AGDR), among others. A new Skyrme energy density functional named SAMi is introduced with the aim of going a step forward in setting the bases for a more precise description of spin-isospin resonances [1, 2]. In addition, we will discuss some new features of our analysis on the AGDR in {sup 208}Pb [3] as compared with available experimental data on this resonance [4, 5, 6], and on the GDR [7]. Such study, guided by a simple yet physical pocket formula, has been developed by employing the so called SAMi-J family of systematically varied interactions. This set of interactions is compatible with experimental data for values of the symmetry energy at saturation J and slope parameter L falling in the ranges 31−33 MeV and 75−95 MeV, respectively.

  10. A new Skyrme energy density functional for a better description of spin-isospin resonances

    NASA Astrophysics Data System (ADS)

    Roca-Maza, X.; Colò, G.; Cao, Li-Gang; Sagawa, H.

    2015-10-01

    A correct determination of the isospin and spin-isospin properties of the nuclear effective interaction should lead to an accurate description of the Gamow-Teller resonance (GT), the Spin Dipole Resonance (SDR), the Giant Dipole Resonance (GDR) or the Antianalog Giant Dipole Resonance (AGDR), among others. A new Skyrme energy density functional named SAMi is introduced with the aim of going a step forward in setting the bases for a more precise description of spin-isospin resonances [1, 2]. In addition, we will discuss some new features of our analysis on the AGDR in 208Pb [3] as compared with available experimental data on this resonance [4, 5, 6], and on the GDR [7]. Such study, guided by a simple yet physical pocket formula, has been developed by employing the so called SAMi-J family of systematically varied interactions. This set of interactions is compatible with experimental data for values of the symmetry energy at saturation J and slope parameter L falling in the ranges 31-33 MeV and 75-95 MeV, respectively.

  11. Description of induced nuclear fission with Skyrme energy functionals: Static potential energy surfaces and fission fragment properties

    NASA Astrophysics Data System (ADS)

    Schunck, N.; Duke, D.; Carr, H.; Knoll, A.

    2014-11-01

    Eighty years after its experimental discovery, a description of induced nuclear fission based solely on the interactions between neutrons and protons and quantum many-body methods still poses formidable challenges. The goal of this paper is to contribute to the development of a predictive microscopic framework for the accurate calculation of static properties of fission fragments for hot fission and thermal or slow neutrons. To this end, we focus on the 239Pu(n ,f ) reaction and employ nuclear density functional theory with Skyrme energy densities. Potential energy surfaces are computed at the Hartree-Fock-Bogoliubov approximation with up to five collective variables. We find that the triaxial degree of freedom plays an important role, both near the fission barrier and at scission. The impact of the parametrization of the Skyrme energy density and the role of pairing correlations on deformation properties from the ground state up to scission are also quantified. We introduce a general template for the quantitative description of fission fragment properties. It is based on the careful analysis of scission configurations, using both advanced topological methods and recently proposed quantum many-body techniques. We conclude that an accurate prediction of fission fragment properties at low incident neutron energies, although technologically demanding, should be within the reach of current nuclear density functional theory.

  12. Extended Structures in RNA Folding Intermediates Are Due to Nonnative Interactions Rather than Electrostatic Repulsion

    SciTech Connect

    Baird, Nathan J.; Gong, Haipeng; Zaheer, Syed S.; Freed, Karl F.; Pan, Tao; Sosnick, Tobin R.

    2010-05-25

    RNA folding occurs via a series of transitions between metastable intermediate states for Mg{sup 2+} concentrations below those needed to fold the native structure. In general, these folding intermediates are considerably less compact than their respective native states. Our previous work demonstrates that the major equilibrium intermediate of the 154-residue specificity domain (S-domain) of the Bacillus subtilis RNase P RNA is more extended than its native structure. We now investigate two models with falsifiable predictions regarding the origins of the extended intermediate structures in the S-domains of the B. subtilis and the Escherichia coli RNase P RNA that belong to different classes of P RNA and have distinct native structures. The first model explores the contribution of electrostatic repulsion, while the second model probes specific interactions in the core of the folding intermediate. Using small-angle X-ray scattering and Langevin dynamics simulations, we show that electrostatics plays only a minor role, whereas specific interactions largely account for the extended nature of the intermediate. Structural contacts in the core, including a nonnative base pair, help to stabilize the intermediate conformation. We conclude that RNA folding intermediates adopt extended conformations due to short-range, nonnative interactions rather than generic electrostatic repulsion of helical domains. These principles apply to other ribozymes and riboswitches that undergo functionally relevant conformational changes.

  13. Study on interaction between induced and natural fractures by extended finite element method

    NASA Astrophysics Data System (ADS)

    Xu, DanDan; Liu, ZhanLi; Zhuang, Zhuo; Zeng, QingLei; Wang, Tao

    2017-02-01

    Fracking is one of the kernel technologies in the remarkable shale gas revolution. The extended finite element method is used in this paper to numerically investigate the interaction between hydraulic and natural fractures, which is an important issue of the enigmatic fracture network formation in fracking. The criteria which control the opening of natural fracture and crossing of hydraulic fracture are tentatively presented. Influence factors on the interaction process are systematically analyzed, which include the approach angle, anisotropy of in-situ stress and fluid pressure profile.

  14. Integrated Physics Advances in Simulation of Wave Interactions with Extended MHD Phenomena

    SciTech Connect

    Batchelor, Donald B; D'Azevedo, Eduardo; Bateman, Glenn; Bernholdt, David E; Berry, Lee A; Bonoli, P.; Bramley, R; Breslau, J.; Chance, M.; Chen, J.; Choi, M.; Elwasif, Wael R; Fu, GuoYong; Harvey, R. W.; Houlberg, Wayne A; Jaeger, Erwin Frederick; Jardin, S. C.; Keyes, David E; Klasky, Scott A; Kruger, Scott; Ku, Long-Poe; McCune, Douglas; Schissel, D.; Schnack, D.; Wright, J. C.

    2007-06-01

    The broad scientific objectives of the SWIM (Simulation of Wave Interaction with MHD) project are: (A) To improve our understanding of interactions that both RF wave and particle sources have on extended-MHD phenomena, and to substantially improve our capability for predicting and optimizing the performance of burning plasmas in devices such as ITER: and (B) To develop an integrated computational system for treating multi-physics phenomena with the required flexibility and extensibility to serve as a prototype for the Fusion Simulation Project (FSP).

  15. Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera)

    PubMed Central

    Snell, Terry W.; Johnston, Rachel K.; Rabeneck, Brett; Zipperer, Cody; Teat, Stephanie

    2014-01-01

    The TOR kinase pathway is central in modulating aging in a variety of animal models. The target of rapamycin (TOR) integrates a complex network of signals from growth conditions, nutrient availability, energy status, and physiological stresses and matches an organism’s growth rate to the resource environment. Important problems remaining are to identify the pathways that interact with TOR and characterize them as additive or synergistic. One of the most versatile stress sensors in metazoans is the Jun-N-terminal Kinase (JNK) signalling pathway. JNK is an evolutionarily conserved stress-activated protein kinase that is induced by a range of stressors, including UV irradiation, reactive oxygen species, DNA damage, heat, and bacterial antigens. JNK is thought to interact with the TOR pathway, but its effects on TOR are poorly understood. We used the rotifer Brachionus manjavacas as a model animal to probe the regulation of TOR and JNK pathways and explore their interaction. The effect of various chemical inhibitors was examined in life table and stressor challenge experiments. A survey of 12 inhibitors revealed two, rapamycin and JNK inhibitor, that significantly extended lifespan of B. manjavacas. At 1 μM concentration, exposure to rapamycin or JNK inhibitor extended mean rotifer lifespan by 35% and maximum lifespan by 37%. Exposure to both rapamycin and JNK inhibitor simultaneously extended mean rotifer lifespan 65% more than either alone. Exposure to a combination of rapamycin and JNK inhibitors conveyed greater protection to starvation, UV and osmotic stress than either inhibitor alone. RNAi knockdown of TOR and JNK gene expression was investigated for its ability to extend rotifer lifespan. RNAi knockdown of the TOR gene resulted in 29% extension of mean lifespan compared to control and knockdown of the JNK gene resulted in 51% mean lifespan extension. In addition to lifespan, we quantified mitochondria activity using the fluorescent marker Mitotracker and

  16. Joint inhibition of TOR and JNK pathways interacts to extend the lifespan of Brachionus manjavacas (Rotifera).

    PubMed

    Snell, Terry W; Johnston, Rachel K; Rabeneck, Brett; Zipperer, Cody; Teat, Stephanie

    2014-04-01

    The TOR kinase pathway is central in modulating aging in a variety of animal models. The target of rapamycin (TOR) integrates a complex network of signals from growth conditions, nutrient availability, energy status, and physiological stresses and matches an organism's growth rate to the resource environment. Important remaining problems are the identification of the pathways that interact with TOR and their characterization as additive or synergistic. One of the most versatile stress sensors in metazoans is the Jun-N-terminal kinase (JNK) signaling pathway. JNK is an evolutionarily conserved stress-activated protein kinase that is induced by a range of stressors, including UV irradiation, reactive oxygen species, DNA damage, heat, and bacterial antigens. JNK is thought to interact with the TOR pathway, but its effects on TOR are poorly understood. We used the rotifer Brachionus manjavacas as a model animal to probe the regulation of TOR and JNK pathways and explore their interaction. The effect of various chemical inhibitors was examined in life table and stressor challenge experiments. A survey of 12 inhibitors revealed two, rapamycin and JNK inhibitor, that significantly extended lifespan of B. manjavacas. At 1 μM concentration, exposure to rapamycin or JNK inhibitor extended mean rotifer lifespan by 35% and maximum lifespan by 37%. Exposure to both rapamycin and JNK inhibitor simultaneously extended mean rotifer lifespan by 65% more than either alone. Exposure to a combination of rapamycin and JNK inhibitors conveyed greater protection to starvation, UV and osmotic stress than either inhibitor alone. RNAi knockdown of TOR and JNK gene expression was investigated for its ability to extend rotifer lifespan. RNAi knockdown of the TOR gene resulted in 29% extension of the mean lifespan compared to control and knockdown of the JNK gene resulted in 51% mean lifespan extension. In addition to the lifespan, we quantified mitochondria activity using the fluorescent

  17. Further explorations of Skyrme-Hartree-Fock-Bogoliubov mass formulas. XIII. The 2012 atomic mass evaluation and the symmetry coefficient

    NASA Astrophysics Data System (ADS)

    Goriely, S.; Chamel, N.; Pearson, J. M.

    2013-08-01

    Our family of three Hartree-Fock-Bogoliubov (HFB) mass models, labeled BSk19, BSk20, and BSk21, is here extended by (a) refitting to the 2012 Atomic Mass Evaluation (AME), and (b) varying the symmetry coefficient J. Five new models, labeled BSk22 to BSk26, along with their mass tables, HFB-22 to HFB-26, respectively, are presented. These models are characterized by unconventional Skyrme forces containing t4 and t5 terms, i.e., density-dependent generalizations of the usual t1 and t2 terms, respectively. Highly realistic contact pairing forces are used. The Skyrme forces are constrained to fit realistic equations of state of neutron matter stiff enough to support the massive neutron stars PSR J1614-2230 and PSR J0348+0432. Unphysical spin and spin-isospin instabilities of homogeneous nuclear matter, including the transition to a polarized state in neutron-star matter, are eliminated with the new forces. The best fits to the new database of 2353 nuclei are found for models BSk24 (J=30 MeV) and BSk25 (J=29 MeV), for which the root-mean square (rms) deviations are 0.55 and 0.54 MeV, respectively. Despite the larger database this is even better than the rms deviation of 0.58 MeV that we found with our fits to the 2003 AME. With J=32 MeV the rms deviation rises to 0.63 MeV. The neutron-skin thicknesses derived from antiproton scattering are shown to be consistent with the conclusions that we have drawn from masses.

  18. Numerical study of rotor-stator interactions in a hydraulic turbine with Foam-extend

    NASA Astrophysics Data System (ADS)

    Romain, Cappato; Guibault, François; Devals, Christophe; Nennemann, Bernd

    2016-11-01

    In the development of high head hydraulic turbines, vibrations are one of the critical problems. In Francis turbines, pressure fluctuations occur at the interface between the blades of the runner and guide vanes. This rotor-stator interaction can be responsible for fatigue failures and cracks. Although the flow inside the turbomachinery is complex, and the unsteadiness makes it difficult to model, the choice of an appropriate setup enables the study of this phenomenon. This study validates a numerical setup of the Foam-extend open source software for rotor-stator simulations. Pressure fluctuations results show a good correspondence with data from experiments.

  19. New topological structures of Skyrme theory: baryon number and monopole number

    NASA Astrophysics Data System (ADS)

    Cho, Y. M.; Kimm, Kyoungtae; Yoon, J. H.; Zhang, Pengming

    2017-02-01

    Based on the observation that the skyrmion in Skyrme theory can be viewed as a dressed monopole, we show that the skyrmions have two independent topology, the baryon topology π _3(S^3) and the monopole topology π _2(S^2). With this we propose to classify the skyrmions by two topological numbers ( m, n), the monopole number m and the shell (radial) number n. In this scheme the popular (non spherically symmetric) skyrmions are classified as the ( m, 1) skyrmions but the spherically symmetric skyrmions are classified as the (1, n) skyrmions, and the baryon number B is given by B=mn. Moreover, we show that the vacuum of the Skyrme theory has the structure of the vacuum of the Sine-Gordon theory and QCD combined together, which can also be classified by two topological numbers ( p, q). This puts the Skyrme theory in a totally new perspective.

  20. An Outline of the Life and Work of Tony Hilton Royle Skyrme (1922-1987)

    NASA Astrophysics Data System (ADS)

    Dalitz, R. H.

    1922-43: Youth and Education - Tony Hilton Royle Skyrme was born on 5 December 1922 at 7 Blessington Road, Lewisham (Kent), London, the family house occupied by his maternal grandparents. His parents were John (sometimes Jack) Hilton Royle Skyrme, a bank clerk, and Muriel May née Roberts, who had been married at St. Margaret's Church in the parish of St. Margaret's and Eastney, in Portsmouth (Hants.), on 25 March 1922. Tony's paternal grandparents were James Henry Rowland Skyrme and Minnie née Hilton, the former being a schoolmaster at Combwitch, near Bridgewater (Somerset), when Tony's father was born in 1896. Tony's maternal grandfather was Herbert William Thomson Roberts, a tidal computer for the Admiralty by profession. The inclusion of Lord Kelvin's baptismal name (William Thomson) among his forenames reflects the professional contact which Tony's great - grandfather had with Lord Kelvin and the high regard in which he held the latter …

  1. Skyrme RPA description of γ-vibrational states in rare-earth nuclei

    NASA Astrophysics Data System (ADS)

    Nesterenko, V. O.; Kartavenko, V. G.; Kleinig, W.; Kvasil, J.; Repko, A.; Jolos, R. V.; Reinhard, P.-G.

    2016-01-01

    The lowest γ-vibrational states with Kπ = 2+γ in well-deformed Dy, Er and Yb isotopes are investigated within the self-consistent separable quasiparticle random-phase-approximation (QRPA) approach based on the Skyrme functional. The energies Eγ and reduced transition probabilities B(E2)γ of the states are calculated with the Skyrme force SV-mas10. We demonstrate the strong effect of the pairing blocking on the energies of γ-vibrational states. It is also shown that collectivity of γ-vibrational states is strictly determined by keeping the Nilsson selection rules in the corresponding lowest 2qp configurations.

  2. Applications of Skyrme energy-density functional to fusion reactions for synthesis of superheavy nuclei

    SciTech Connect

    Wang Ning; Scheid, Werner; Wu Xizhen; Liu Min; Li Zhuxia

    2006-10-15

    The Skyrme energy-density functional approach has been extended to study massive heavy-ion fusion reactions. Based on the potential barrier obtained and the parametrized barrier distribution the fusion (capture) excitation functions of a lot of heavy-ion fusion reactions are studied systematically. The average deviations of fusion cross sections at energies near and above the barriers from experimental data are less than 0.05 for 92% of 76 fusion reactions with Z{sub 1}Z{sub 2}<1200. For the massive fusion reactions, for example, the {sup 238}U-induced reactions and {sup 48}Ca+{sup 208}Pb, the capture excitation functions have been reproduced remarkably well. The influence of structure effects in the reaction partners on the capture cross sections is studied with our parametrized barrier distribution. By comparing the reactions induced by double-magic nucleus {sup 48}Ca and by {sup 32}S and {sup 35}Cl, the ''threshold-like'' behavior in the capture excitation function for {sup 48}Ca-induced reactions is explored and an optimal balance between the capture cross section and the excitation energy of the compound nucleus is studied. Finally, the fusion reactions with {sup 36}S, {sup 37}Cl, {sup 48}Ca, and {sup 50}Ti bombarding {sup 248}Cm, {sup 247,249}Bk, {sup 250,252,254}Cf, and {sup 252,254}Es, as well as the reactions leading to the same compound nucleus with Z=120 and N=182, are studied further. The calculation results for these reactions are useful for searching for the optimal fusion configuration and suitable incident energy in the synthesis of superheavy nuclei.

  3. Extended binding inhibitors of chymotrypsin that interact with leaving group subsites S1'-S3'.

    PubMed

    Imperiali, B; Abeles, R H

    1987-07-14

    We have synthesized inhibitors of chymotrypsin, based on fluoromethyl ketones, that bind at S and S' subsites. "Small" inhibitors of serine proteases, which have previously been synthesized, only interact with S subsites. The parent compound is Ac-Leu-ambo-Phe-CF2H (1) (Ki = 25 X 10(-6) M). This inhibitor was modified by successively replacing H of the -CF2H group by -CH2CH2CONHCH3, (4), -CH2CH2CONH-Leu-NHMe (5), -CH2CH2CONH-Leu-Val-OEt (6), and -CH2CH2CONH-Leu-Arg-OMe (7). Corresponding Ki values are 7.8 (4), 0.23 (5), 0.21 (6), and 0.014 (7) microM. Extending 5 to 6 by addition of Val-OEt at P3' does not decrease Ki. In contrast, extension of 5 to 7 by incorporating Arg-OMe at P3' decreases Ki approximately 15-fold, suggesting interaction between Arg and the S3' subsite but no corresponding interaction at that subsite with Val. These results are in accordance with results obtained with the homologous family of avian ovomucoid third domain proteins. Proteins with Arg at the P3' position show highly favorable interactions with the protease at the S3' subsite [Park, S. J. (1985) Ph.D. Thesis, Purdue University; M. Laskowski, Jr., personal communication]. These results establish that incorporation of residues which interact with S' subsites significantly increases the efficacy of inhibitors and that valuable information concerning the most effective amino acid composition of small inhibitors can be obtained from the amino acid sequence of protein inhibitors.

  4. RGM study of the NN interaction in an extended quark model

    NASA Astrophysics Data System (ADS)

    Fujiwara, Y.; Hecht, K. T.

    1987-02-01

    The extended quark model study of the NN interaction, in which the ( q overlineq) excitations inherent in the quark-gluon interaction are explicitly incorporated into the model space, is completed with the inclusion of the ( q overlineq) ( q overlineq) excitations generated by RPA-type terms of the color Breit interaction. The new coupling kernels connecting the dominant (3q)-(3q) components of the NN system to the (3 q)-(3 q)( q overlineq)( q overlineq) components lead to potentials with the characteristics of conventional σ and δ meson exchange potentials and furnish the additional medium-range attraction needed to bind the deuteron. The full model is subjected to a quantitative test through a solution of the RGM equations in a coupled channel formalism. With one improvement of the model, to yield an Nπ tensor force with OPEP strength and long-range characteristics, this model leads to a prediction of the low-energy NN scattering data and deuteron bound state characteristics which is in semiquantitative agreement with the experimental data and is free of parameter adjustments.

  5. Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.

    PubMed

    Tremblay, Michel G; Herdman, Chelsea; Guillou, François; Mishra, Prakash K; Baril, Joëlle; Bellenfant, Sabrina; Moss, Tom

    2015-06-26

    We previously demonstrated that ESyt2 interacts specifically with the activated FGF receptor and is required for a rapid phase of receptor internalization and for functional signaling via the ERK pathway in early Xenopus embryos. ESyt2 is one of the three-member family of Extended Synaptotagmins that were recently shown to be implicated in the formation of endoplasmic reticulum (ER)-plasma membrane (PM) junctions and in the Ca(2+) dependent regulation of these junctions. Here we show that ESyt2 is directed to the ER by its putative transmembrane domain, that the ESyts hetero- and homodimerize, and that ESyt2 homodimerization in vivo requires a TM adjacent sequence but not the SMP domain. ESyt2 and ESyt3, but not ESyt1, selectively interact in vivo with activated FGFR1. In the case of ESyt2, this interaction requires a short TM adjacent sequence and is independent of receptor autophosphorylation, but dependent on receptor conformation. The data show that ESyt2 recognizes a site in the upper kinase lobe of FGFR1 that is revealed by displacement of the kinase domain activation loop during receptor activation.

  6. Pairwise Interaction Extended Point Particle (PIEP) Model for a Random Array of Spheres

    NASA Astrophysics Data System (ADS)

    Akiki, Georges; Jackson, Thomas; Balachandar, Sivaramakrishnan; CenterCompressible Multiphase Turbulence Team

    2016-11-01

    This study investigates a flow past random array of spherical particles. The understanding of the governing forces within these arrays is crucial for obtaining accurate models used in particle-laden simulations. These models have to faithfully reflect the sub-grid interactions between the particles and the continuous phase. The models being used today assumes an average force on all particles within the array based on the mean volume fraction and Reynolds number. Here, we develop a model which can compute the drag and lateral forces on each particle by accounting for the precise location of few surrounding neighbors. A pairwise interaction is assumed where the perturbation flow induced by each neighbor is considered separately, then the effect of all neighbors are linearly superposed to obtain the total perturbation. Faxén correction is used to quantify the force perturbation due to the presence of the neighbors. The single neighbor perturbations are mapped in the vicinity of a reference sphere and stored as libraries. We test the Pairwise Interaction Extended Point-Particle (PIEP) model for random arrays at two different volume fractions of ϕ = 0 . 1 and 0.21 and Reynolds number in the range 16 <= Re <= 170 . The PIEP model predictions are compared against drag and lift forces obtained from fully-resolved DNS performed using immersed boundary method. We observe the PIEP model prediction to correlate much better with the DNS results than the classical mean drag model prediction.

  7. Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers

    PubMed Central

    Arumughan, Anup; Roske, Yvette; Barth, Carolin; Forero, Laura Lleras; Bravo-Rodriguez, Kenny; Redel, Alexandra; Kostova, Simona; McShane, Erik; Opitz, Robert; Faelber, Katja; Rau, Kirstin; Mielke, Thorsten; Daumke, Oliver; Selbach, Matthias; Sanchez-Garcia, Elsa; Rocks, Oliver; Panáková, Daniela; Heinemann, Udo; Wanker, Erich E.

    2016-01-01

    Interaction mapping is a powerful strategy to elucidate the biological function of protein assemblies and their regulators. Here, we report the generation of a quantitative interaction network, directly linking 14 human proteins to the AAA+ ATPase p97, an essential hexameric protein with multiple cellular functions. We show that the high-affinity interacting protein ASPL efficiently promotes p97 hexamer disassembly, resulting in the formation of stable p97:ASPL heterotetramers. High-resolution structural and biochemical studies indicate that an extended UBX domain (eUBX) in ASPL is critical for p97 hexamer disassembly and facilitates the assembly of p97:ASPL heterotetramers. This spontaneous process is accompanied by a reorientation of the D2 ATPase domain in p97 and a loss of its activity. Finally, we demonstrate that overproduction of ASPL disrupts p97 hexamer function in ERAD and that engineered eUBX polypeptides can induce cell death, providing a rationale for developing anti-cancer polypeptide inhibitors that may target p97 activity. PMID:27762274

  8. Preliminary Model for the Solar Wind Interaction with Pluto's Extended Plasma Tail

    NASA Astrophysics Data System (ADS)

    Sillanpää, I.; Ebert, R.; Elliott, H.; Kallio, E.

    2012-04-01

    We are developing a hybrid model of the Pluto plasma environment (HYB-Pluto) to study the solar wind interaction with Pluto's plasma tail to distances of 1000 Pluto radii (RP) while still resolving the shock and/or wave features upstream of Pluto with good resolution. The HYB-Pluto model features an extended domain and adaptable grid structure along with important processes such as ion-neutral interactions. We present results from our first simulations with the HYB-Pluto model that used realistic values for the solar wind bulk properties and included He++ ions. The results show the formation of a bow shock upstream of Pluto as well as asymmetries of ion density and bow shock in the direction of the convection electric field. This model, along with other current models [1], will provide tools to interpret and understand the plasma observations obtained during expected encounter of the New Horizons spacecraft with the Pluto system in July 2015. [1] P.A. Delamere, Hybrid Code Simulations of the Solar Wind Interaction with Pluto, J. Geophys. Res., 114, A03220, doi:10.1029/2008JA013756, 2009.

  9. Interactive Visualization of 3-D Mantle Convection Extended Through AJAX Applications

    NASA Astrophysics Data System (ADS)

    McLane, J. C.; Czech, W.; Yuen, D.; Greensky, J.; Knox, M. R.

    2008-12-01

    We have designed a new software system for real-time interactive visualization of results taken directly from large-scale simulations of 3-D mantle convection and other large-scale simulations. This approach allows for intense visualization sessions for a couple of hours as opposed to storing massive amounts of data in a storage system. Our data sets consist of 3-D data for volume rendering with over 10 million unknowns at each timestep. Large scale visualization on a display wall holding around 13 million pixels has already been accomplished with extension to hand-held devices, such as the OQO and Nokia N800 and recently the iPHONE. We are developing web-based software in Java to extend the use of this system across long distances. The software is aimed at creating an interactive and functional application capable of running on multiple browsers by taking advantage of two AJAX-enabled web frameworks: Echo2 and Google Web Toolkit. The software runs in two modes allowing for a user to control an interactive session or observe a session controlled by another user. Modular build of the system allows for components to be swapped out for new components so that other forms of visualization could be accommodated such as Molecular Dynamics in mineral physics or 2-D data sets from lithospheric regional models.

  10. Study of An Extended Interaction Oscillator with A Rectangular Reentrance Coupled-cavity in Terahertz Region

    NASA Astrophysics Data System (ADS)

    Zhang, Kaichun; Wu, Zhenhua; Liu, Shenggang

    2009-04-01

    An extended interaction oscillator (EIO) generating Terahertz (THz) wave is presented by theoretical study and simulation study in this paper. A rectangular reentrant coupled-cavity is proposed as its slow-wave structure (SWS). The equivalent circuit method (ECM) is adopted to calculate the dispersion relation and circuit parameters of the SWS. The beam-wave interaction of the EIO is theoretically studied in detail, including the beam loading conductance, the conversion efficiency and the optimal gap number. The dependence is investigated of the beam loading conductance and the conversion efficiency on the gap number and the beam velocity. Some properties of the cold circuit are simulated by CST software, including the dispersion relation and the filed distribution. These simulation results agree well with those of ECM. The operating mode of EIO is chosen very close to the β L = 2π point with corresponding frequency about 0.225 THz, when the beam voltage is 13 kV, the current 105 mA, the cavity was designed with the period 0.3 mm, 14-gap, the height 1.6 mm and the width 0.76 mm . Simulation results of beam-wave interaction with PIC codes show that the excited frequency is 0.225 THz and peak output power 44 W.

  11. Design of a C-band relativistic extended interaction klystron with coaxial output cavity

    NASA Astrophysics Data System (ADS)

    Yang, Wu; Zhao, De-Kui; Chen, Yong-Dong

    2015-07-01

    In order to overcome the disadvantages of conventional high frequency relativistic klystron amplifiers in power capability and RF conversion efficiency, a C-band relativistic extended interaction klystron amplifier with coaxial output cavity is designed with the aid of PIC code MAGIC. In the device, disk-loaded cavities are introduced in the input and intermediate cavity to increase the beam modulation depth, and a coaxial disk-loaded cavity is employed in the output cavity to enhance the RF conversion efficiency. In PIC simulation, when the beam voltage is 680 kV and current is 4 kA, the device can generate 1.11 GW output power at 5.64 GHz with an efficiency of 40.8%.

  12. Extended ALE Method for fluid-structure interaction problems with large structural displacements

    NASA Astrophysics Data System (ADS)

    Basting, Steffen; Quaini, Annalisa; Čanić, Sunčica; Glowinski, Roland

    2017-02-01

    Standard Arbitrary Lagrangian-Eulerian (ALE) methods for the simulation of fluid-structure interaction (FSI) problems fail due to excessive mesh deformations when the structural displacement is large. We propose a method that successfully deals with this problem, keeping the same mesh connectivity while enforcing mesh alignment with the structure. The proposed Extended ALE Method relies on a variational mesh optimization technique, where mesh alignment with the structure is achieved via a constraint. This gives rise to a constrained optimization problem for mesh optimization, which is solved whenever the mesh quality deteriorates. The performance of the proposed Extended ALE Method is demonstrated on a series of numerical examples involving 2D FSI problems with large displacements. Two-way coupling between the fluid and structure is considered in all the examples. The FSI problems are solved using either a Dirichlet-Neumann algorithm, or a Robin-Neumann algorithm. The Dirichlet-Neumann algorithm is enhanced by an adaptive relaxation procedure based on Aitken's acceleration. We show that the proposed method has excellent performance in problems with large displacements, and that it agrees well with a standard ALE method in problems with mild displacement.

  13. Mapping and Modeling the Extended Winds of the Massive Interacting Binary, Eta Carinae

    NASA Technical Reports Server (NTRS)

    Gull, Ted

    2010-01-01

    The combination HST/STIS high spatial and moderate spectral resolutions have revealed the massive interacting wind structure of Eta Carinae by forbidden lines of singly and doubly ionized elements. Throughout the 5.54-year period, lines of Fe++, Ne++, Ar++, S++ and N+ reveal the interacting wind structures, near critical electron densities of 10(exp 5) to 3 x 10(exp 7)cu cm, photoionized by the hot secondary, Eta Car B, Lines of Fe+ and Ni+ trace the denser (>10(exp 7)cu cm. less-ionized (< 8 eV) primary wind of Eta Car A as it wraps around the interacting binary stars. For 5 years of the 5.54 year period, the FUV radiation from Eta Car B escapes the orbital region, ionizing the boundaries of the expanding wind structures. But for three to six months, Eta Car B plunges into the primary wind approaching to within 1 to 2 AU, leading to cutoff of FUV and X-ray fluxes. The interacting wind structure, resolved out to 0.8", drops io ionization and then rebuilds as Eta Car B emerges from the primary wind envelope. Solid Particle Hydrodynamical(SPH) models have been developed extending out to 2000 AU and adapted to include FUV radiation effects of the winds. In turn, synthetic spectroimages of selected forbidden lines have been constructed and compared to the spectroimages recorded by the HST/STIS throughout 1998.0 to 2004.3, extending across the 1998 and 2003.5 minima. By this method, we show that the orbital axis of the binary system must bc within 15 degrees of the Homunculus axis of symmetry and that periastron occurs with Eta Car B passing on the far side of Eta Car B. This result ties the current binary orbit with the bipolar ejection with intervening skirt and leads to implications that the binary system influenced the mass ejection of the l840s and the lesser ejection of the 1890s.

  14. Using 4th order Runge-Kutta method for solving a twisted Skyrme string equation

    NASA Astrophysics Data System (ADS)

    Hadi, Miftachul; Anderson, Malcolm; Husein, Andri

    2016-03-01

    We study numerical solution, especially using 4th order Runge-Kutta method, for solving a twisted Skyrme string equation. We find numerically that the value of minimum energy per unit length of vortex solution for a twisted Skyrmion string is 20.37 × 1060 eV/m.

  15. Towards the establishment of nonlinear hidden symmetries of the Skyrme model

    SciTech Connect

    Herrera-Aguilar, A.; Kanakoglou, K.; Paschalis, J. E.

    2006-09-25

    We present a preliminary attempt to establish the existence of hidden nonlinear symmetries of the SU(N) Skyrme model which could, in principle, lead to the further integration of the system. An explicit illustration is given for the SU(2) symmetry group.

  16. Roles of urea and TMAO on the interaction between extended non-polar peptides

    NASA Astrophysics Data System (ADS)

    Su, Zhaoqian; Dias, Cristiano

    Urea and trimethylamine n-oxide (TMAO) are small molecules known to destabilize and stabilize, respectively, the structure of proteins when added to aqueous solution. To unravel the molecular mechanisms of these cosolvents on protein structure we perform explicit all-atom molecular dynamics simulations of extended poly-alanine and polyleucine dimers. We use an umbrella sampling protocol to compute the potential of mean force (PMF) of dimers at different concentrations of urea and TMAO. We find that the large non-polar side chain of leucine is affected by urea whereas backbone atoms and alanine's side chain are not. Urea is found to occupy positions between leucine's side chains that are not accessible to water. This accounts for extra Lennard-Jones bonds between urea and side chains that favors the unfolded state. These bonds compete with urea-solvent interactions that favor the folded state. The sum of these two energetic terms provide the enthalpic driving force for unfolding. We show here that this enthalpy correlate with the potential of mean force of poly-leucine dimers. Moreover, the framework developed here is general and may be used to provide insights into effects of other small molecules on protein interactions. The effect of the TMAO will be in the presentation. Department of Physics, University Heights, Newark, New Jersey, 07102-1982.

  17. Exact solutions to a spatially extended model of kinase-receptor interaction.

    PubMed

    Szopa, Piotr; Lipniacki, Tomasz; Kazmierczak, Bogdan

    2011-10-01

    B and Mast cells are activated by the aggregation of the immune receptors. Motivated by this phenomena we consider a simple spatially extended model of mutual interaction of kinases and membrane receptors. It is assumed that kinase activates membrane receptors and in turn the kinase molecules bound to the active receptors are activated by transphosphorylation. Such a type of interaction implies positive feedback and may lead to bistability. In this study we apply the Steklov eigenproblem theory to analyze the linearized model and find exact solutions in the case of non-uniformly distributed membrane receptors. This approach allows us to determine the critical value of receptor dephosphorylation rate at which cell activation (by arbitrary small perturbation of the inactive state) is possible. We found that cell sensitivity grows with decreasing kinase diffusion and increasing anisotropy of the receptor distribution. Moreover, these two effects are cooperating. We showed that the cell activity can be abruptly triggered by the formation of the receptor aggregate. Since the considered activation mechanism is not based on receptor crosslinking by polyvalent antigens, the proposed model can also explain B cell activation due to receptor aggregation following binding of monovalent antigens presented on the antigen presenting cell.

  18. Exact solutions to a spatially extended model of kinase-receptor interaction

    NASA Astrophysics Data System (ADS)

    Szopa, Piotr; Lipniacki, Tomasz; Kazmierczak, Bogdan

    2011-10-01

    B and Mast cells are activated by the aggregation of the immune receptors. Motivated by this phenomena we consider a simple spatially extended model of mutual interaction of kinases and membrane receptors. It is assumed that kinase activates membrane receptors and in turn the kinase molecules bound to the active receptors are activated by transphosphorylation. Such a type of interaction implies positive feedback and may lead to bistability. In this study we apply the Steklov eigenproblem theory to analyze the linearized model and find exact solutions in the case of non-uniformly distributed membrane receptors. This approach allows us to determine the critical value of receptor dephosphorylation rate at which cell activation (by arbitrary small perturbation of the inactive state) is possible. We found that cell sensitivity grows with decreasing kinase diffusion and increasing anisotropy of the receptor distribution. Moreover, these two effects are cooperating. We showed that the cell activity can be abruptly triggered by the formation of the receptor aggregate. Since the considered activation mechanism is not based on receptor crosslinking by polyvalent antigens, the proposed model can also explain B cell activation due to receptor aggregation following binding of monovalent antigens presented on the antigen presenting cell.

  19. Extended Bose Hubbard model of interacting bosonic atoms in optical lattices: From superfluidity to density waves

    SciTech Connect

    Mazzarella, G.; Giampaolo, S. M.; Illuminati, F.

    2006-01-15

    For systems of interacting, ultracold spin-zero neutral bosonic atoms, harmonically trapped and subject to an optical lattice potential, we derive an Extended Bose Hubbard (EBH) model by developing a systematic expansion for the Hamiltonian of the system in powers of the lattice parameters and of a scale parameter, the lattice attenuation factor. We identify the dominant terms that need to be retained in realistic experimental conditions, up to nearest-neighbor interactions and nearest-neighbor hoppings conditioned by the on-site occupation numbers. In the mean field approximation, we determine the free energy of the system and study the phase diagram both at zero and at finite temperature. At variance with the standard on site Bose Hubbard model, the zero-temperature phase diagram of the EBH model possesses a dual structure in the Mott insulating regime. Namely, for specific ranges of the lattice parameters, a density wave phase characterizes the system at integer fillings, with domains of alternating mean occupation numbers that are the atomic counterparts of the domains of staggered magnetizations in an antiferromagnetic phase. We show as well that in the EBH model, a zero-temperature quantum phase transition to pair superfluidity is, in principle, possible, but completely suppressed at the lowest order in the lattice attenuation factor. Finally, we determine the possible occurrence of the different phases as a function of the experimentally controllable lattice parameters.

  20. Self-quartic interaction for a scalar field in an extended DFR noncommutative space-time

    NASA Astrophysics Data System (ADS)

    Abreu, Everton M. C.; Neves, M. J.

    2014-07-01

    The framework of Dopliche-Fredenhagen-Roberts (DFR) for a noncommutative (NC) space-time is considered as an alternative approach to study the NC space-time of the early Universe. Concerning this formalism, the NC constant parameter, θ, is promoted to coordinate of the space-time and consequently we can describe a field theory in a space-time with extra-dimensions. We will see that there is a canonical momentum associated with this new coordinate in which the effects of a new physics can emerge in the propagation of the fields along the extra-dimensions. The Fourier space of this framework is automatically extended by the addition of the new momenta components. The main concept that we would like to emphasize from the outset is that the formalism demonstrated here will not be constructed by introducing a NC parameter in the system, as usual. It will be generated naturally from an already NC space. We will review that when the components of the new momentum are zero, the (extended) DFR approach is reduced to the usual (canonical) NC case, in which θ is an antisymmetric constant matrix. In this work we will study a scalar field action with self-quartic interaction ϕ4⋆ defined in the DFR NC space-time. We will obtain the Feynman rules in the Fourier space for the scalar propagator and vertex of the model. With these rules we are able to build the radiative corrections to one loop order of the model propagator. The consequences of the NC scale, as well as the propagation of the field in extra-dimensions, will be analyzed in the ultraviolet divergences scenario. We will investigate about the actual possibility that this kμν conjugate momentum has the property of healing the combination of IR/UV divergences that emerges in this recently new NC spacetime quantum field theory.

  1. Interacting Boson Model and nucleons

    NASA Astrophysics Data System (ADS)

    Otsuka, Takaharu

    2012-10-01

    An overview on the recent development of the microscopic derivation of the Interacting Boson Model is presented with some remarks not found elsewhere. The OAI mapping is reviewed very briefly, including the basic correspondence from nucleon-pair to boson. The new fermionboson mapping method is introduced, where intrinsic states of nucleons and bosons for a wide variation of shapes play an important role. Nucleon intrinsic states are obtained from mean field models, which is Skyrme model in examples to be shown. This method generates IBM-2 Hamiltonian which can describe and predict various situations of quadrupole collective states, including U(5), SU(3), O(6) and E(5) limits. The method is extended so that rotational response (cranking) can be handled, which enables us to describe rotational bands of strongly deformed nuclei. Thus, we have obtained a unified framework for the microscopic derivation of the IBM covering all known situations of quadrupole collectivity at low energy.

  2. The search for extended infrared emission near interacting and active galaxies

    NASA Technical Reports Server (NTRS)

    Appleton, Philip N.

    1991-01-01

    The following subject areas are covered: the search for extended far IR emission; the search for extended emission in galaxy groups; a brief review of the flattening algorithm; the target groups; extended emission from groups and intergalactic HI clouds; and morphological image processing.

  3. Infinite matter properties and zero-range limit of non-relativistic finite-range interactions

    NASA Astrophysics Data System (ADS)

    Davesne, D.; Becker, P.; Pastore, A.; Navarro, J.

    2016-12-01

    We discuss some infinite matter properties of two finite-range interactions widely used for nuclear structure calculations, namely Gogny and M3Y interactions. We show that some useful informations can be deduced for the central, tensor and spin-orbit terms from the spin-isospin channels and the partial wave decomposition of the symmetric nuclear matter equation of state. We show in particular that the central part of the Gogny interaction should benefit from the introduction of a third Gaussian and the tensor parameters of both interactions can be deduced from special combinations of partial waves. We also discuss the fact that the spin-orbit of the M3Y interaction is not compatible with local gauge invariance. Finally, we show that the zero-range limit of both families of interactions coincides with the specific form of the zero-range Skyrme interaction extended to higher momentum orders and we emphasize from this analogy its benefits.

  4. Interactive computer programs for petrologic modeling with extended Q-mode factor analysis

    USGS Publications Warehouse

    Miesch, A.T.

    1976-01-01

    An extended form of Q-mode factor analysis may be used if the row-sums of the data matrix are constant and can be helpful especially in developing and testing petrologic-mixing models for igneous systems. The first step is to represent the sample compositions as unit vectors in M-dimensional space and then to project them into space of fewer dimensions (m) as determined to be appropriate from a factor-variance diagram. Compositions thought to be those of possible end-members in the petrologic system then are represented as vectors in the M-dimensional space and projected into the same space as the sample vectors. If these vectors remain close to unity in length after projection, the corresponding compositions can serve as end-member compositions for the model. After m suitable end-member compositions have been identified, each sample composition is expressed as a mixture of the end-members by computation of the composition loadings. The interactive computer programs presented are useful in these procedures because of the trial-and-error nature of the modeling procedures. ?? 1976.

  5. A high-order mode extended interaction klystron at 0.34 THz

    NASA Astrophysics Data System (ADS)

    Wang, Dongyang; Wang, Guangqiang; Wang, Jianguo; Li, Shuang; Zeng, Peng; Teng, Yan

    2017-02-01

    We propose the concept of high-order mode extended interaction klystron (EIK) at the terahertz band. Compared to the conventional fundamental mode EIK, it operates at the TM31-2π mode, and its remarkable advantage is to obtain a large structure and good performance. The proposed EIK consists of five identical cavities with five gaps in each cavity. The method is discussed to suppress the mode competition and self-oscillation in the high-order mode cavity. Particle-in-cell simulation demonstrates that the EIK indeed operates at TM31-2π mode without self-oscillation while other modes are well suppressed. Driven by the electron beam with a voltage of 15 kV and a current of 0.3 A, the saturation gain of 43 dB and the output power of 60 W are achieved at the center frequency of 342.4 GHz. The EIK operating at high-order mode seems a promising approach to generate high power terahertz waves.

  6. Exact solution of the Einstein-Skyrme model in a Kantowski-Sachs spacetime

    NASA Astrophysics Data System (ADS)

    Paliathanasis, Andronikos; Tsamparlis, Michael

    2017-04-01

    We consider a Skyrme fluid with a constant radial profile in locally rotational Kantowski-Sachs spacetime. The Skyrme fluid is an anisotropic fluid with zero heat flux and with an equation of state parameter wS that |ws | ≤ 1/3. From the Einstein field equations we define the Wheeler-DeWitt equation. For the last equation we perform a Lie symmetry classification and we determine the invariant solutions for the wavefunction of the model. Moreover from the Lie symmetries of the Wheeler-DeWitt equation we construct Noetherian conservation laws for the field equations which we use in order to write the solution in closed form. We show that all of the cosmological parameters are expressed in terms of the scale factor of the two dimensional sphere of the Kantowski-Sachs spacetime. Finally from the application of Noether's theorem for the Wheeler-DeWitt equation we derive conservation laws for the wavefunction of the universe.

  7. Dynamic Nuclear Polarization enhanced NMR at 187 GHz/284 MHz using an Extended Interaction Klystron amplifier

    NASA Astrophysics Data System (ADS)

    Kemp, Thomas F.; Dannatt, Hugh R. W.; Barrow, Nathan S.; Watts, Anthony; Brown, Steven P.; Newton, Mark E.; Dupree, Ray

    2016-04-01

    A Dynamic Nuclear Polarisation (DNP) enhanced solid-state Magic Angle Spinning (MAS) NMR spectrometer which uses a 187 GHz (corresponding to 1H NMR frequency of 284 MHz) Extended Interaction Klystron (EIK) amplifier as the microwave source is briefly described. Its performance is demonstrated for a biomolecule (bacteriorhodopsin), a pharmaceutical, and surface functionalised silica. The EIK is very compact and easily incorporated into an existing spectrometer. The bandwidth of the amplifier is sufficient that it obviates the need for a sweepable magnetic field, once set, for all commonly used radicals. The variable power (CW or pulsed) output from the EIK is transmitted to the DNP-NMR probe using a quasi-optic system with a high power isolator and a corrugated waveguide which feeds the microwaves into the DNP-NMR probe. Curved mirrors inside the probe project the microwaves down the axis of the MAS rotor, giving a very efficient system such that maximum DNP enhancement is achieved with less than 3 W output from the microwave source. The DNP-NMR probe operates with a sample temperature down to 90 K whilst spinning at 8 kHz. Significant enhancements, in excess of 100 for bacteriorhodopsin in purple membrane (bR in PM), are shown along with spectra which are enhanced by ≈25 with respect to room temperature, for both the pharmaceutical furosemide and surface functionalised silica. These enhancements allow hitherto prohibitively time consuming experiments to be undertaken. The power at which the DNP enhancement in bR in PM saturates does not change significantly between 90 K and 170 K even though the enhancement drops by a factor of ≈11. As the DNP build up time decreases by a factor 3 over this temperature range, the reduction in T1n is presumably a significant contribution to the drop in enhancement.

  8. Do Skyrme forces that fit nuclear matter work well in finite nuclei?

    NASA Astrophysics Data System (ADS)

    Stevenson, P. D.; Goddard, P. M.; Stone, J. R.; Dutra, M.

    2013-05-01

    A short list of Skyrme force parameterizations, recently found to have passed a series of constraints relating to nuclear matter properties is analyzed for their ability to reproduce data in finite nuclei. We analyse binding energies, isotope shifts, neutron skin thicknesses and fission barriers. We find that the subset of forces have no common ability to reproduce(or otherwise)properties of finite nuclei, despite passing the extensive range of nuclear matter constraints.

  9. Fission Half Lives of Fermium Isotopes Within Skyrme Hartree-Fock Theory

    NASA Astrophysics Data System (ADS)

    Baran, A.; Staszczak, A.; Nazarewicz, W.

    Nuclear fission barriers, mass parameters and spontaneous fission half lives of fermium isotopes calculated in a framework of the Skyrme Hartree-Fock-Bogoliubov model with the SkM* force are discussed. Zero-point energy corrections in the ground state are determined for each nucleus using the Gaussian overlap approximation of the generator coordinate method and in the cranking formalism. Results of spontaneous fission half lives are compared to experimental data.

  10. FISSION HALF LIVES OF FERMIUM ISOTOPES WITHIN SKYRME HARTREE-FOCK-BOGOLIUBOV THEORY

    SciTech Connect

    Baran, A.; Staszczak, Andrzej; Nazarewicz, A.

    2011-01-01

    Nuclear fission barriers, mass parameters and spontaneous fission half lives of fermium isotopes calculated in a framework of the Skyrme Hartree-Fock-Bogoliubov model with the SkM* force are discussed. Zero-point energy corrections in the ground state are determined for each nucleus using the Gaussian overlap approximation of the generator coordinate method and in the cranking formalism. Results of spontaneous fission half lives are compared to experimental data.

  11. Baryons with open beauty dynamically generated from meson-baryon interaction in the extended local hidden gauge approach

    NASA Astrophysics Data System (ADS)

    Liang, Wei-Hong; Xiao, C. W.; Oset, E.

    2016-05-01

    In this talk we review the results about the interaction of B ¯N , B ¯Δ, B ¯*N and B ¯*Δ states with beauty B = 1, together with their coupled channels, using the extended local hidden gauge approach. The Λb(5912) and Λb(5920) observed in the experiment are dynamically generated from the meson-baryon interaction, and they couple mostly to B ¯*N , which are degenerate with the Weinberg-Tomozawa interaction. In addition, three more states with I = 0 and eight more states with I = 1 are predicted.

  12. Nuclear charge and neutron radii and nuclear matter: Trend analysis in Skyrme density-functional-theory approach

    NASA Astrophysics Data System (ADS)

    Reinhard, P.-G.; Nazarewicz, W.

    2016-05-01

    Background: Radii of charge and neutron distributions are fundamental nuclear properties. They depend on both nuclear interaction parameters related to the equation of state of infinite nuclear matter and on quantal shell effects, which are strongly impacted by the presence of nuclear surface. Purpose: In this work, by studying the correlation of charge and neutron radii, and neutron skin, with nuclear matter parameters, we assess different mechanisms that drive nuclear sizes. Method: We apply nuclear density functional theory using a family of Skyrme functionals obtained by means of optimization protocols, which do not include any radius information. By performing the Monte Carlo sampling of reasonable functionals around the optimal parametrization, we scan all correlations between nuclear matter properties and observables characterizing charge and neutron distributions of spherical closed-shell nuclei 48Ca,208Pb, and 298Fl. Results: By considering the influence of various nuclear matter properties on charge and neutron radii in a multidimensional parameter space of Skyrme functionals, we demonstrate the existence of two strong relationships: (i) between the nuclear charge radii and the saturation density of symmetric nuclear matter ρ0, and (ii) between the neutron skins and the slope of the symmetry energy L . The impact of other nuclear matter properties on nuclear radii is weak or nonexistent. For functionals optimized to experimental binding energies only, proton and neutron radii are found to be weakly correlated due to canceling trends from different nuclear matter characteristics. Conclusion: The existence of only two strong relations connecting nuclear radii with nuclear matter properties has important consequences. First, by requiring that the nuclear functional reproduces the empirical saturation point of symmetric nuclear matter practically fixes the charge (or proton) radii, and vice versa. This explains the recent results of ab initio calculations

  13. Extended weak bonding interactions in DNA: pi-stacking (base-base), base-backbone, and backbone-backbone interactions.

    PubMed

    Matta, Chérif F; Castillo, Norberto; Boyd, Russell J

    2006-01-12

    We report on several weak interactions in nucleic acids, which, collectively, can make a nonnegligible contribution to the structure and stability of these molecules. Fragments of DNA were obtained from previously determined accurate experimental geometries and their electron density distributions calculated using density functional theory (DFT). The electron densities were analyzed topologically according to the quantum theory of atoms in molecules (AIM). A web of closed-shell bonding interactions is shown to connect neighboring base pairs in base-pair duplexes and in dinuleotide steps. This bonding underlies the well-known pi-stacking interaction between adjacent nucleic acid bases and is characterized topologically for the first time. Two less widely appreciated modes of weak closed-shell interactions in nucleic acids are also described: (i) interactions between atoms in the bases and atoms belonging to the backbone (base-backbone) and (ii) interactions among atoms within the backbone itself (backbone-backbone). These interactions include hydrogen bonding, dihydrogen bonding, hydrogen-hydrogen bonding, and several other weak closed-shell X-Y interactions (X, Y = O, N, C). While each individual interaction is very weak and typically accompanied by perhaps 0.5-3 kcal/mol, the sum total of these interactions is postulated to play a role in stabilizing the structure of nucleic acids. The Watson-and-Crick hydrogen bonding is also characterized in detail at the experimental geometries as a prelude to the discussion of the modes of interactions listed in the title.

  14. Determination of partial unfolding enthalpy for lysozyme upon interaction with dodecyltrimethylammonium bromide using an extended solvation model.

    PubMed

    Behbehani, G Rezaei; Saboury, A A; Taleshi, E

    2008-01-01

    The interactions of dodecyltrimethylammonium bromides (DTABs) with hen egg lysozyme have been investigated at pH = 7.0 and 27 degrees C in phosphate buffer by isothermal titration calorimetry. DTAB interacts endothermically and activate lysozyme. The endothermicity of the lysozyme-DTAB interaction is in marked contrast to the exothermic interactions between sodium dodecyl sulphate (SDS) and lysozyme which have been attributed to specific binding between the anionic sulphate head groups and cationic amino acid residues. The enthalpies of interaction between the cationic surfactant (DTAB) and lysozyme are dominated by the endothermic unfolding of the native structure followed by an exothermic solvation of the lysozyme-DTAB complex by the addition of extra DTAB. A new direct calorimetric method to follow protein denaturation, and the effect of surfactants on the stability of proteins was introduced. The extended solvation model was used to reproduce the enthalpies of lysozyme-DTAB interaction over the whole range of DTAB concentrations. The solvation parameters recovered from the new equation, attributed to the structural change of lysozyme and its biological activity. At low concentrations of DTAB, the binding is mainly electrostatic, with some simultaneous interaction of the hydrophobic tail with nearby hydrophobic patches on the lysozyme. These initial interactions presumably cause some protein unfolding and expose additional hydrophobic sites. The DTAB-induced denaturation enthalpy of lysozyme is 86.46 +/- 0.02 kJ mol(-1).

  15. Extended asymmetric hot region formation due to shockwave interactions following void collapse in shocked high explosive

    DOE PAGES

    Shan, Tzu -Ray; Wixom, Ryan R.; Thompson, Aidan P.

    2016-08-01

    In both continuum hydrodynamics simulations and also multimillion atom reactive molecular dynamics simulations of shockwave propagation in single crystal pentaerythritol tetranitrate (PETN) containing a cylindrical void, we observed the formation of an initial radially symmetric hot spot. By extending the simulation time to the nanosecond scale, however, we observed the transformation of the small symmetric hot spot into a longitudinally asymmetric hot region extending over a much larger volume. Performing reactive molecular dynamics shock simulations using the reactive force field (ReaxFF) as implemented in the LAMMPS molecular dynamics package, we showed that the longitudinally asymmetric hot region was formed bymore » coalescence of the primary radially symmetric hot spot with a secondary triangular hot zone. We showed that the triangular hot zone coincided with a double-shocked region where the primary planar shockwave was overtaken by a secondary cylindrical shockwave. The secondary cylindrical shockwave originated in void collapse after the primary planar shockwave had passed over the void. A similar phenomenon was observed in continuum hydrodynamics shock simulations using the CTH hydrodynamics package. Furthermore, the formation and growth of extended asymmetric hot regions on nanosecond timescales has important implications for shock initiation thresholds in energetic materials.« less

  16. Extended asymmetric hot region formation due to shockwave interactions following void collapse in shocked high explosive

    NASA Astrophysics Data System (ADS)

    Shan, Tzu-Ray; Wixom, Ryan R.; Thompson, Aidan P.

    2016-08-01

    In both continuum hydrodynamics simulations and also multimillion atom reactive molecular dynamics simulations of shockwave propagation in single crystal pentaerythritol tetranitrate (PETN) containing a cylindrical void, we observed the formation of an initial radially symmetric hot spot. By extending the simulation time to the nanosecond scale, however, we observed the transformation of the small symmetric hot spot into a longitudinally asymmetric hot region extending over a much larger volume. Performing reactive molecular dynamics shock simulations using the reactive force field (ReaxFF) as implemented in the LAMMPS molecular dynamics package, we showed that the longitudinally asymmetric hot region was formed by coalescence of the primary radially symmetric hot spot with a secondary triangular hot zone. We showed that the triangular hot zone coincided with a double-shocked region where the primary planar shockwave was overtaken by a secondary cylindrical shockwave. The secondary cylindrical shockwave originated in void collapse after the primary planar shockwave had passed over the void. A similar phenomenon was observed in continuum hydrodynamics shock simulations using the CTH hydrodynamics package. The formation and growth of extended asymmetric hot regions on nanosecond timescales has important implications for shock initiation thresholds in energetic materials.

  17. Extended asymmetric hot region formation due to shockwave interactions following void collapse in shocked high explosive

    SciTech Connect

    Shan, Tzu -Ray; Wixom, Ryan R.; Thompson, Aidan P.

    2016-08-01

    In both continuum hydrodynamics simulations and also multimillion atom reactive molecular dynamics simulations of shockwave propagation in single crystal pentaerythritol tetranitrate (PETN) containing a cylindrical void, we observed the formation of an initial radially symmetric hot spot. By extending the simulation time to the nanosecond scale, however, we observed the transformation of the small symmetric hot spot into a longitudinally asymmetric hot region extending over a much larger volume. Performing reactive molecular dynamics shock simulations using the reactive force field (ReaxFF) as implemented in the LAMMPS molecular dynamics package, we showed that the longitudinally asymmetric hot region was formed by coalescence of the primary radially symmetric hot spot with a secondary triangular hot zone. We showed that the triangular hot zone coincided with a double-shocked region where the primary planar shockwave was overtaken by a secondary cylindrical shockwave. The secondary cylindrical shockwave originated in void collapse after the primary planar shockwave had passed over the void. A similar phenomenon was observed in continuum hydrodynamics shock simulations using the CTH hydrodynamics package. Furthermore, the formation and growth of extended asymmetric hot regions on nanosecond timescales has important implications for shock initiation thresholds in energetic materials.

  18. Toroidal Nuclear Matter Distributions of Superheavy Nuclei from Constrained Skyrme-HFB Calculations

    SciTech Connect

    Kosior, Amelia; Staszczak, A.; Wong, Cheuk-Yin

    2017-01-01

    Using the Hartree Fock Bogoliubov (HFB) self-consistent mean-field theory with the SkM* Skyrme energy-density functional, we study nuclear structure properties of even even superheavy nuclei (SHN) of Z = 120 isotopes and N = 184 isotones. The shape of the nucleus along the lowest energy curve as a function of the quadrupole moment Q20 makes a sud- den transition from the oblate spheroids (biconcave discs) to the toroidal shapes, in the region of large oblate quadrupole moments.

  19. Quantum SU(3) Skyrme model with noncanonical embedded SO(3) soliton

    SciTech Connect

    Jurciukonis, D.; Norvaisas, E.

    2007-05-15

    The new ansatz which is the SO(3) group soliton was defined for the SU(3) Skyrme model. The model is considered in noncanonical bases SU(3) superset of SO(3) for the state vectors. A complete canonical quantization of the model has been investigated in the collective coordinate formalism for the fundamental SU(3) representation of the unitary field. The independent quantum variable manifold covers all the eight dimension SU(3) group manifold due to the new ansatz. The explicit expressions of the Lagrangian and Hamiltonian densities are derived for this modified quantum skyrmion.

  20. Rotational 2+ states of superheavy elements in the Skyrme-Hartree-Fock-Bogoliubov model

    NASA Astrophysics Data System (ADS)

    Baran, A.; Staszczak, A.

    2013-05-01

    The Skyrme-Hartree-Fock-Bogoliubov calculations of the energies of first 2+ rotational states of deformed superheavy (SH) elements in the region of 108 ⩽ Z ⩽ 126 and 148 ⩽ N ⩽ 180 are reported. The results agree well in the case of fermium isotopes after a proper scaling of the moment of inertia. The scaling factor equals 1.3. The extension of the model to the region of SH elements gives a possibility of better estimation of the Q-values of α-decay, which is a dominant decay mode of SH elements.

  1. Constraints on the Skyrme equations of state from properties of doubly magic nuclei.

    PubMed

    Brown, B Alex

    2013-12-06

    I use properties of doubly magic nuclei to constrain symmetric nuclear matter and neutron matter equations of state. I conclude that these data determine the value of the neutron equation of state at a density of ρ(on)=0.10  nucleons/fm3 to be 11.4(10) MeV. The slope at that point is constrained by the value of the neutron skin. Analytical equations are given that show the dependence of the Skyrme equations of state on the neutron skin.

  2. Improving intermolecular interactions in DFTB3 using extended polarization from chemical-potential equalization

    SciTech Connect

    Christensen, Anders S. E-mail: cui@chem.wisc.edu; Cui, Qiang E-mail: cui@chem.wisc.edu; Elstner, Marcus

    2015-08-28

    Semi-empirical quantum mechanical methods traditionally expand the electron density in a minimal, valence-only electron basis set. The minimal-basis approximation causes molecular polarization to be underestimated, and hence intermolecular interaction energies are also underestimated, especially for intermolecular interactions involving charged species. In this work, the third-order self-consistent charge density functional tight-binding method (DFTB3) is augmented with an auxiliary response density using the chemical-potential equalization (CPE) method and an empirical dispersion correction (D3). The parameters in the CPE and D3 models are fitted to high-level CCSD(T) reference interaction energies for a broad range of chemical species, as well as dipole moments calculated at the DFT level; the impact of including polarizabilities of molecules in the parameterization is also considered. Parameters for the elements H, C, N, O, and S are presented. The Root Mean Square Deviation (RMSD) interaction energy is improved from 6.07 kcal/mol to 1.49 kcal/mol for interactions with one charged species, whereas the RMSD is improved from 5.60 kcal/mol to 1.73 for a set of 9 salt bridges, compared to uncorrected DFTB3. For large water clusters and complexes that are dominated by dispersion interactions, the already satisfactory performance of the DFTB3-D3 model is retained; polarizabilities of neutral molecules are also notably improved. Overall, the CPE extension of DFTB3-D3 provides a more balanced description of different types of non-covalent interactions than Neglect of Diatomic Differential Overlap type of semi-empirical methods (e.g., PM6-D3H4) and PBE-D3 with modest basis sets.

  3. Correction for solute/solvent interaction extends accurate freezing point depression theory to high concentration range.

    PubMed

    Fullerton, G D; Keener, C R; Cameron, I L

    1994-12-01

    The authors describe empirical corrections to ideally dilute expressions for freezing point depression of aqueous solutions to arrive at new expressions accurate up to three molal concentration. The method assumes non-ideality is due primarily to solute/solvent interactions such that the correct free water mass Mwc is the mass of water in solution Mw minus I.M(s) where M(s) is the mass of solute and I an empirical solute/solvent interaction coefficient. The interaction coefficient is easily derived from the constant in the linear regression fit to the experimental plot of Mw/M(s) as a function of 1/delta T (inverse freezing point depression). The I-value, when substituted into the new thermodynamic expressions derived from the assumption of equivalent activity of water in solution and ice, provides accurate predictions of freezing point depression (+/- 0.05 degrees C) up to 2.5 molal concentration for all the test molecules evaluated; glucose, sucrose, glycerol and ethylene glycol. The concentration limit is the approximate monolayer water coverage limit for the solutes which suggests that direct solute/solute interactions are negligible below this limit. This is contrary to the view of many authors due to the common practice of including hydration forces (a soft potential added to the hard core atomic potential) in the interaction potential between solute particles. When this is recognized the two viewpoints are in fundamental agreement.

  4. Attachment of bacteriophages MS2 and PhiX174 onto kaolinite and montmorillonite: extended-DLVO interactions

    NASA Astrophysics Data System (ADS)

    Chrysikopoulos, C. V.; Syngouna, V. I.

    2012-04-01

    This study aims to gain insights into the interaction of virus particles with clay colloids. Bacteriophages MS2 and ΦX174 were used as model viruses and kaolinite (KGa-1b) and montmorillonite (STx-1b) as model colloids. The experimental data obtained from batch experiments of MS2 and ΦX174 attachment onto KGa-1b and STx-1b suggested that virus attachment is adequately described by the Freundlich isotherm equation. Both MS2 and ΦX174 were attached in greater amounts onto KGa-1b than STx-1b with MS2 having greater affinity than ΦX174 for both clays. Furthermore, extended-DLVO interaction energy calculations explained that the attachment of viruses onto model clay colloids was primarily caused by hydrophobic interaction. The theoretical and experimental results of this study were found to be in good agreement with previous findings.

  5. Attachment of bacteriophages MS2 and ΦX174 onto kaolinite and montmorillonite: extended-DLVO interactions.

    PubMed

    Chrysikopoulos, Constantinos V; Syngouna, Vasiliki I

    2012-04-01

    This study aims to gain insights into the interaction of virus particles with clay colloids. Bacteriophages MS2 and ΦX174 were used as model viruses and kaolinite (KGa-1b) and montmorillonite (STx-1b) as model colloids. The experimental data obtained from batch experiments of MS2 and ΦX174 attachment onto KGa-1b and STx-1b suggested that virus attachment is adequately described by the Freundlich isotherm equation. Both MS2 and ΦX174 were attached in greater amounts onto KGa-1b than STx-1b with MS2 having greater affinity than ΦX174 for both clays. Furthermore, extended-DLVO interaction energy calculations explained that the attachment of viruses onto model clay colloids was primarily caused by hydrophobic interaction. The theoretical and experimental results of this study were found to be in good agreement with previous findings.

  6. Studying generalised dark matter interactions with extended halo-independent methods

    SciTech Connect

    Kahlhoefer, Felix; Wild, Sebastian

    2016-10-20

    The interpretation of dark matter direct detection experiments is complicated by the fact that neither the astrophysical distribution of dark matter nor the properties of its particle physics interactions with nuclei are known in detail. To address both of these issues in a very general way we develop a new framework that combines the full formalism of non-relativistic effective interactions with state-of-the-art halo-independent methods. This approach makes it possible to analyse direct detection experiments for arbitrary dark matter interactions and quantify the goodness-of-fit independent of astrophysical uncertainties. We employ this method in order to demonstrate that the degeneracy between astrophysical uncertainties and particle physics unknowns is not complete. Certain models can be distinguished in a halo-independent way using a single ton-scale experiment based on liquid xenon, while other models are indistinguishable with a single experiment but can be separated using combined information from several target elements.

  7. Studying generalised dark matter interactions with extended halo-independent methods

    NASA Astrophysics Data System (ADS)

    Kahlhoefer, Felix; Wild, Sebastian

    2016-10-01

    The interpretation of dark matter direct detection experiments is complicated by the fact that neither the astrophysical distribution of dark matter nor the properties of its particle physics interactions with nuclei are known in detail. To address both of these issues in a very general way we develop a new framework that combines the full formalism of non-relativistic effective interactions with state-of-the-art halo-independent methods. This approach makes it possible to analyse direct detection experiments for arbitrary dark matter interactions and quantify the goodness-of-fit independent of astrophysical uncertainties. We employ this method in order to demonstrate that the degeneracy between astrophysical uncertainties and particle physics unknowns is not complete. Certain models can be distinguished in a halo-independent way using a single ton-scale experiment based on liquid xenon, while other models are indistinguishable with a single experiment but can be separated using combined information from several target elements.

  8. Outer satellite atmospheres: Their extended nature and planetary interactions. [sodium cloud of Io, hydrogen torus of Titan, and comet atmospheres

    NASA Technical Reports Server (NTRS)

    Smyth, W. H.

    1980-01-01

    Highly developed numerical models are applied to interpret extended-atmosphere data for the sodium cloud of Io and the hydrogen torus of Titan. Solar radiation pressure was identified and verified by model calculations as the mechanism to explain two different east-west asymmetries observed in the sodium cloud. Analysis of sodium line profile data, suggesting that a Jupiter magnetospheric wind may be responsible for high speed sodium atoms emitted from Io, and preliminary modeling of the interaction of the Io plasma torus and Io's sodium cloud are also reported. Models presented for Titan's hydrogen torus are consistent both with the recent Pioneer 11 measurements and earlier Earth-orbiting observations by the Copernicus satellite. Progress is reported on developing models for extended gas and dust atmospheres of comets.

  9. Extended Fluid-Dynamics and Collective Motion of Two Trapped Fermion Species with Pairing Interactions

    NASA Astrophysics Data System (ADS)

    Hernández, E. S.; Capuzzi, P.; Szybisz, L.

    2011-02-01

    We extend our earlier fluid-dynamical description of fermion superfluids incorporating the particle energy flow together with the equation of motion for the internal kinetic energy of the pairs. The formal scheme combines a set of equations similar to those of classical hydrodynamics with the equations of motion for the anomalous density and for its related momentum density and kinetic energy density. This dynamical frame represents a second order truncation of an infinite hierarchy of equations of motion isomorphic to the full time dependent Hartree-Fock-Bogoliubov equations in coordinate representation. We analyze the equilibrium solutions and fluctuations for a homogeneous, unpolarized fermion system of two species, and show that the collective spectrum presents the well-known Anderson-Bogoliubov low energy mode of homogeneous superfluids and a pairing vibration near the gap energy.

  10. Self-consistent theory of finite Fermi systems and Skyrme-Hartree-Fock method

    NASA Astrophysics Data System (ADS)

    Saperstein, E. E.; Tolokonnikov, S. V.

    2016-11-01

    Recent results obtained on the basis of the self-consistent theory of finite Fermi systems by employing the energy density functional proposed by Fayans and his coauthors are surveyed. These results are compared with the predictions of Skyrme-Hartree-Fock theory involving several popular versions of the Skyrme energy density functional. Spherical nuclei are predominantly considered. The charge radii of even and odd nuclei and features of low-lying 2+ excitations in semimagic nuclei are discussed briefly. The single-particle energies ofmagic nuclei are examined inmore detail with allowance for corrections to mean-field theory that are induced by particle coupling to low-lying collective surface excitations (phonons). The importance of taking into account, in this problem, nonpole (tadpole) diagrams, which are usually disregarded, is emphasized. The spectroscopic factors of magic and semimagic nuclei are also considered. In this problem, only the surface term stemming from the energy dependence induced in the mass operator by the exchange of surface phonons is usually taken into account. The volume contribution associated with the energy dependence initially present in the mass operator within the self-consistent theory of finite Fermi systems because of the exchange of high-lying particle-hole excitations is also included in the spectroscopic factor. The results of the first studies that employed the Fayans energy density functional for deformed nuclei are also presented.

  11. Extended magnetic exchange interactions in the high-temperature ferromagnet MnBi

    SciTech Connect

    Christianson, Andrew D.; Hahn, Steven E.; Fishman, Randy Scott; Parker, David S.; McGuire, Michael A.; Sales, Brian C.; Lumsden, Mark D.; Williams, T. J.; Taylor, A. E.

    2016-05-09

    Here, the high-temperature ferromagnet MnBi continues to receive attention as a candidate to replace rare-earth-containing permanent magnets in applications above room temperature. This is due to a high Curie temperature, large magnetic moments, and a coercivity that increases with temperature. The synthesis of MnBi also allows for crystals that are free of interstitial Mn, enabling more direct access to the key interactions underlying the physical properties of binary Mn-based ferromagnets. In this work, we use inelastic neutron scattering to measure the spin waves of MnBi in order to characterize the magnetic exchange at low temperature. Consistent with the spin reorientation that occurs below 140~K, we do not observe a spin gap in this system above our experimental resolution. A Heisenberg model was fit to the spin wave data in order to characterize the long-range nature of the exchange. It was found that interactions up to sixth nearest neighbor are required to fully parameterize the spin waves. Surprisingly, the nearest-neighbor term is antiferromagnetic, and the realization of a ferromagnetic ground state relies on the more numerous ferromagnetic terms beyond nearest neighbor, suggesting that the ferromagnetic ground state arises as a consequence of the long-ranged interactions in the system.

  12. Extended magnetic exchange interactions in the high-temperature ferromagnet MnBi

    DOE PAGES

    Christianson, Andrew D.; Hahn, Steven E.; Fishman, Randy Scott; ...

    2016-05-09

    Here, the high-temperature ferromagnet MnBi continues to receive attention as a candidate to replace rare-earth-containing permanent magnets in applications above room temperature. This is due to a high Curie temperature, large magnetic moments, and a coercivity that increases with temperature. The synthesis of MnBi also allows for crystals that are free of interstitial Mn, enabling more direct access to the key interactions underlying the physical properties of binary Mn-based ferromagnets. In this work, we use inelastic neutron scattering to measure the spin waves of MnBi in order to characterize the magnetic exchange at low temperature. Consistent with the spin reorientationmore » that occurs below 140~K, we do not observe a spin gap in this system above our experimental resolution. A Heisenberg model was fit to the spin wave data in order to characterize the long-range nature of the exchange. It was found that interactions up to sixth nearest neighbor are required to fully parameterize the spin waves. Surprisingly, the nearest-neighbor term is antiferromagnetic, and the realization of a ferromagnetic ground state relies on the more numerous ferromagnetic terms beyond nearest neighbor, suggesting that the ferromagnetic ground state arises as a consequence of the long-ranged interactions in the system.« less

  13. Interaction-induced two-photon edge states in an extended Hubbard model realized in a cavity array

    NASA Astrophysics Data System (ADS)

    Gorlach, Maxim A.; Poddubny, Alexander N.

    2017-03-01

    We study theoretically two-photon states in a periodic array of coupled cavities with both on-site and nonlocal Kerr-type nonlinearities. In the absence of nonlinearity the structure is topologically trivial and possesses no edge states. The interplay of two nonlinear interaction mechanisms described by the extended Hubbard model facilitates the formation of edge states of bound photon pairs. Numerical and exact analytical results for the two-photon wave functions are presented. Our findings thus shed light onto the edge states of composite particles and their localization properties.

  14. High flux, narrow bandwidth compton light sources via extended laser-electron interactions

    DOEpatents

    Barty, V P

    2015-01-13

    New configurations of lasers and electron beams efficiently and robustly produce high flux beams of bright, tunable, polarized quasi-monoenergetic x-rays and gamma-rays via laser-Compton scattering. Specifically, the use of long-duration, pulsed lasers and closely-spaced, low-charge and low emittance bunches of electron beams increase the spectral flux of the Compton-scattered x-rays and gamma rays, increase efficiency of the laser-electron interaction and significantly reduce the overall complexity of Compton based light sources.

  15. Definition of the residues required for the interaction between glycine-extended gastrin and transferrin in vitro.

    PubMed

    Kovac, Suzana; Ferrand, Audrey; Estève, Jean-Pierre; Mason, Anne B; Baldwin, Graham S

    2009-09-01

    Transferrin is the main iron transport protein found in the circulation, and the level of transferrin saturation in the blood is an important indicator of iron status. The peptides amidated gastrin(17) (Gamide) and glycine-extended gastrin(17) (Ggly) are well known for their roles in controlling acid secretion and as growth factors in the gastrointestinal tract. Several lines of evidence, including the facts that transferrin binds gastrin, that gastrins bind ferric ions, and that the level of expression of gastrins positively correlates with transferrin saturation, suggest the possible involvement of the transferrin-gastrin interaction in iron homeostasis. In the present work, the interaction between gastrins and transferrin has been characterized by surface plasmon resonance and covalent crosslinking. First, an interaction between iron-free apo-transferrin and Gamide or Ggly was observed. The fact that no interaction was observed in the presence of the chelator EDTA suggested that the gastrin-ferric ion complex was the interacting species. Moreover, removal of ferric ions with EDTA reduced the stability of the complex between apo-transferrin and gastrins, and no interaction was observed between Gamide or Ggly and diferric transferrin. Second, some or all of glutamates at positions 8-10 of the Ggly molecule, together with the C-terminal domain, were necessary for the interaction with apo-transferrin. Third, monoferric transferrin mutants incapable of binding iron in either the N-terminal or C-terminal lobe still bound Ggly. These findings are consistent with the hypothesis that gastrin peptides bind to nonligand residues within the open cleft in each lobe of transferrin and are involved in iron loading of transferrin in vivo.

  16. Competing exotic quantum phases of spin- 12 ultracold lattice bosons with extended spin interactions

    DOE PAGES

    Chang, Chia-Chen; Rousseau, Valéry G.; Scalettar, Richard T.; ...

    2015-08-12

    Advances in pure optical trapping techniques now allow the creation of degenerate Bose gases with internal degrees of freedom. Systems such as 87Rb, 39K or 23Na in the F = 1 hyperfine state offer an ideal platform for studying the interplay of super fluidity and quantum magnetism. Motivated by the experimental developments, we study ground state phases of a two-component Bose gas loaded on an optical lattice. We describe this effectively by the Bose-Hubbard Hamiltonian with onsite and near neighbor spin-spin interactions. One important feature of our investigation is the inclusion of interconversion (spin-flip) terms between the two species, whichmore » has been observed in optical lattice experiments. Furthermore, using mean-field theory and quantum Monte Carlo simulations, we map out the phase diagram of the system. A rich variety of phases is identified, including antiferromagnetic (AF) Mott insulators, ferromagnetic and AF super fluids.« less

  17. Interactions of corrosion products and bentonite: An extended multicomponent reactive transport model

    NASA Astrophysics Data System (ADS)

    Lu, Chuanhe; Samper, Javier; Fritz, Bertrand; Clement, Alain; Montenegro, Luis

    Radioactive waste disposal in deep geological repositories envisages various engineered barriers such as carbon-steel canisters and compacted bentonite. Canister corrosion and the chemical interactions of corrosion products with bentonite are key reactions for the long term performance of a repository. Samper, Lu, and Montenegro (Physics and Chemistry of the Earth 2008; 33S: S306-S316) reported numerical models to simulate canister corrosion and the interactions of corrosion products with bentonite for the near field of a repository in granite. Here we present an updated version of their reactive transport model which accounts for: (1) Three types of sorption sites in the bentonite; (2) Kinetically-controlled canister corrosion, (3) Kinetically-controlled magnetite precipitation; and (4) The competition effect of Ni 2+ for sorbing sites. Accounting for kinetically-controlled canister corrosion leads to a significant reduction in the corrosion rate. Uncertainties in the surface complexation reactions play a minor role in the time evolution of the computed pH in the bentonite and the granite. Computed iron concentrations, however, are very sensitive to changes in the surface complexation reactions. The apparent distribution coefficient of Fe computed with the three-site model is 10 times larger than that obtained with a single-site model. The concentration of dissolved Fe computed with kinetic magnetite precipitation is smaller than that obtained with magnetite precipitation at local equilibrium. The largest difference in the concentration of dissolved Fe occurs after 3 × 10 4 years. The competition of Ni 2+ for sorption sites affects significantly the chemical evolution of the bentonite porewater. The sorption of Ni 2+ on bentonite releases protons and therefore the pH in the bentonite is smaller than that computed without Ni 2+ transport. The sorption of Ni 2+ leads to a decrease of the concentration of sorbed Fe and an increase of the concentration of dissolved

  18. An extended hybrid density functional (X3LYP) with improved descriptions of nonbond interactions and thermodynamic properties of molecular systems

    NASA Astrophysics Data System (ADS)

    Xu, Xin; Zhang, Qingsong; Muller, Richard P.; Goddard, William A.

    2005-01-01

    We derive here the form for the exact exchange energy density for a density that decays with Gaussian-type behavior at long range. This functional is intermediate between the B88 and the PW91 exchange functionals. Using this modified functional to match the form expected for Gaussian densities, we propose the X3LYP extended functional. We find that X3LYP significantly outperforms Becke three parameter Lee-Yang-Parr (B3LYP) for describing van der Waals and hydrogen bond interactions, while performing slightly better than B3LYP for predicting heats of formation, ionization potentials, electron affinities, proton affinities, and total atomic energies as validated with the extended G2 set of atoms and molecules. Thus X3LYP greatly enlarges the field of applications for density functional theory. In particular the success of X3LYP in describing the water dimer (with Re and De within the error bars of the most accurate determinations) makes it an excellent candidate for predicting accurate ligand-protein and ligand-DNA interactions.

  19. Collective Behaviors in Spatially Extended Systems with Local Interactions and Synchronous Updating

    NASA Astrophysics Data System (ADS)

    ChatÉ, H.; Manneville, P.

    1992-01-01

    Assessing the extent to which dynamical systems with many degrees of freedom can be described within a thermodynamics formalism is a problem that currently attracts much attention. In this context, synchronously updated regular lattices of identical, chaotic elements with local interactions are promising models for which statistical mechanics may be hoped to provide some insights. This article presents a large class of cellular automata rules and coupled map lattices of the above type in space dimensions d = 2 to 6.Such simple models can be approached by a mean-field approximation which usually reduces the dynamics to that of a map governing the evolution of some extensive density. While this approximation is exact in the d = infty limit, where macroscopic variables must display the time-dependent behavior of the mean-field map, basic intuition from equilibrium statistical mechanics rules out any such behavior in a low-dimensional systems, since it would involve the collective motion of locally disordered elements.The models studied are chosen to be as close as possible to mean-field conditions, i.e., rather high space dimension, large connectivity, and equal-weight coupling between sites. While the mean-field evolution is never observed, a new type of non-trivial collective behavior is found, at odds with the predictions of equilibrium statistical mechanics. Both in the cellular automata models and in the coupled map lattices, macroscopic variables frequently display a non-transient, time-dependent, low-dimensional dynamics emerging out of local disorder. Striking examples are period 3 cycles in two-state cellular automata and a Hopf bifurcation for a d = 5 lattice of coupled logistic maps. An extensive account of the phenomenology is given, including a catalog of behaviors, classification tables for the celular automata rules, and bifurcation diagrams for the coupled map lattices.The observed underlying dynamics is accompanied by an intrinsic quasi-Gaussian noise

  20. Acid-Base Formalism Extended to Excited State for O-H···S Hydrogen Bonding Interaction.

    PubMed

    Bhattacharyya, Surjendu; Roy, Ved Prakash; Wategaonkar, Sanjay

    2016-09-08

    Hydrogen bond can be regarded as an interaction between a base and a proton covalently bound to another base. In this context the strength of hydrogen bond scales with the proton affinity of the acceptor base and the pKa of the donor, i.e., it follows the acid-base formalism. This has been amply demonstrated in conventional hydrogen bonds. Is this also true for the unconventional hydrogen bonds involving lesser electronegative elements such as sulfur atom? In our previous work, we had established that the strength of O-H···S hydrogen bonding (HB) interaction scales with the proton affinity (PA) of the acceptor. In this work, we have investigated the other counterpart, i.e., the H-bonding interaction between the photoacids with different pKa values with a common base such as the H2O and H2S. The 1:1 complexes of five para substituted phenols p-aminophenol, p-cresol, p-fluorophenol, p-chlorophenol, and p-cyanophenol with H2O and H2S were investigated experimentally and computationally. The investigations were also extended to the excited states. The experimental observations of the spectral shifts in the O-H stretching frequency and the S1-S0 band origins were correlated with the pKa of the donors. Ab initio calculations at the MP2 and various dispersion corrected density functional levels of theory were performed to compute the dissociation energy (D0) of the complexes. The quantum theory of atoms in molecules (QTAIM), noncovalent interaction (NCI) method, natural bonding orbital (NBO) analysis, and natural decomposition analysis (NEDA) were carried out for further characterization of HB interaction. The O-H stretching frequency red shifts and the dissociation energies were found to be lower for the O-H···S hydrogen bonded systems compared to those for the O-H···O H-bound systems. Despite being dominated by the dispersion interaction the O-H···S interaction in the H2S complexes also conformed to the acid-base formalism, i.e., the D0 and the O-H red shift

  1. FLUIDS, PLASMAS AND ELECTRIC DISCHARGES: Study of a rectangular coupled cavity extended interaction oscillator in sub-terahertz waves

    NASA Astrophysics Data System (ADS)

    Zhang, Kai-Chun; Wu, Zhen-Hua; Liu, Sheng-Gang

    2008-09-01

    An extended interaction oscillator (EIO) generating 120 GHz wave in sub-terahertz waves is studied by using the three-dimensional electromagnetic simulation software CST and PIC codes. A rectangular reentrant coupled-cavity is proposed as the slow-wave structure of EIO. By CST, the circuit parameters including frequency-phase dispersion, interaction impedance and characteristic impedance are simulated and calculated. The operation mode of EIO is chosen very close to the point where β L = 2π with corresponding frequency 120 GHz, the beam voltage 12 kV and the dimensions of the cavity with the period 0.5 mm, the height 3 mm and the width 1.4 mm. Simulation results of beam-wave interaction by PIC show that the exciting frequency is 120.85 GHz and output peak power 465 W with 12-period coupled-cavity with the perveance 0.17μP. Simulation results indicate that the EIO has very wide range of the operation voltage.

  2. On the spin excitation energy of the nucleon in the Skyrme model

    NASA Astrophysics Data System (ADS)

    Adam, C.; Sanchez-Guillen, J.; Wereszczynski, A.

    2016-11-01

    In the Skyrme model of nucleons and nuclei, the spin excitation energy of the nucleon is traditionally calculated by a fit of the rigid rotor quantization of spin/isospin of the fundamental Skyrmion (the hedgehog) to the masses of the nucleon and the Delta resonance. The resulting, quite large spin excitation energy of the nucleon of about 73MeV is, however, rather difficult to reconcile with the small binding energies of physical nuclei, among other problems. Here, we argue that a more reliable interval of values for the spin excitation energy of the nucleon, compatible with many physical constraints is between 15MeV and 30MeV. The fit of the rigid rotor to the Delta, on the other hand, is problematic in any case, because it implies the use of a nonrelativistic method for a highly relativistic system.

  3. Multidimensional Skyrme-density-functional study of the spontaneous fission of 238U

    SciTech Connect

    Sadhukhan, J.; Mazurek, K.; Dobaczewski, J.; Nazarewicz, W.; Sheikh, J. A.; Baran, A.

    2015-01-01

    We determined the spontaneous fission lifetime of 238U by a minimization of the action integral in a three-dimensional space of collective variables. Apart from the mass-distribution multipole moments Q20 (elongation) and Q30 (left–right asymmetry), we also considered the pairing-fluctuation parameter λ2 as a collective coordinate. The collective potential was obtained self-consistently using the Skyrme energy density functional SkM*. The inertia tensor was obtained within the nonperturbative cranking approximation to the adiabatic time-dependent Hartree–Fock–Bogoliubov approach. As a result, the pairing-fluctuation parameter λ2 allowed us to control the pairing gap along the fission path, which significantly changed the spontaneous fission lifetime.

  4. Multidimensional Skyrme-density-functional study of the spontaneous fission of 238U

    DOE PAGES

    Sadhukhan, J.; Mazurek, K.; Dobaczewski, J.; ...

    2015-01-01

    We determined the spontaneous fission lifetime of 238U by a minimization of the action integral in a three-dimensional space of collective variables. Apart from the mass-distribution multipole moments Q20 (elongation) and Q30 (left–right asymmetry), we also considered the pairing-fluctuation parameter λ2 as a collective coordinate. The collective potential was obtained self-consistently using the Skyrme energy density functional SkM*. The inertia tensor was obtained within the nonperturbative cranking approximation to the adiabatic time-dependent Hartree–Fock–Bogoliubov approach. As a result, the pairing-fluctuation parameter λ2 allowed us to control the pairing gap along the fission path, which significantly changed the spontaneous fission lifetime.

  5. Skyrme random-phase-approximation description of lowest Kπ=2γ+ states in axially deformed nuclei

    NASA Astrophysics Data System (ADS)

    Nesterenko, V. O.; Kartavenko, V. G.; Kleinig, W.; Kvasil, J.; Repko, A.; Jolos, R. V.; Reinhard, P.-G.

    2016-03-01

    The lowest quadrupole γ -vibrational Kπ=2+ states in axially deformed rare-earth (Nd, Sm, Gd, Dy, Er, Yb, Hf, W) and actinide (U) nuclei are systematically investigated within the separable random-phase-approximation (SRPA) based on the Skyrme functional. The energies Eγ and reduced transition probabilities B (E 2 ) of 2γ+ states are calculated with the Skyrme forces SV-bas and SkM*. The energies of two-quasiparticle configurations forming the SRPA basis are corrected by using the pairing blocking effect. This results in a systematic downshift of Eγ by 0.3-0.5 MeV and thus in a better agreement with the experiment, especially in Sm, Gd, Dy, Hf, and W regions. For other isotopic chains, a noticeable overestimation of Eγ and too weak collectivity of 2γ+ states still persist. It is shown that domains of nuclei with low and high 2γ+ collectivity are related to the structure of the lowest two-quasiparticle states and conservation of the Nilsson selection rules. The description of 2γ+ states with SV-bas and SkM* is similar in light rare-earth nuclei but deviates in heavier nuclei. However SV-bas much better reproduces the quadrupole deformation and energy of the isoscalar giant quadrupole resonance. The accuracy of SRPA is justified by comparison with exact RPA. The calculations suggest that a further development of the self-consistent calculation schemes is needed for a systematic satisfactory description of the 2γ+ states.

  6. Equatorial π-stacking interactions in diruthenium (II,III) tetracarboxylate complexes containing extended π-systems

    NASA Astrophysics Data System (ADS)

    O'Rourke, Natasha F.; Ronaldson, Michael; Stanley Cameron, T.; Wang, Ruiyao; Aquino, Manuel A. S.

    2013-11-01

    The synthesis of three new valent-averaged tetracarboxylatodiruthenium (II,III) complexes, [Ru2(1-naphthylacetate)4(H2O)2](PF6)ṡ4THF, 1ṡ4THF, [Ru2(2-naphthoate)4(THF)2](PF6)ṡ3THF, 2ṡ3THF, and [Ru2(coumarin-3-carboxylate)4(MeOH)2](PF6)ṡMeOHṡH2O, 3ṡMeOHṡH2O, was accomplished using a well documented carboxylate exchange reaction. All three complexes were thoroughly characterized using infrared and UV-Vis spectroscopies, elemental analysis and X-ray diffraction. Due to the extended π-systems present, two of the complexes, 2ṡ3THF and 3ṡMeOHṡH2O, display extensive π-stacking in two dimensions, with similar interactions notably absent in 1ṡ4THF due to the perpendicular orientation of the naphthyl rings. Modest H-bonding is seen in complexes 1ṡ4THF and 3ṡMeOHṡH2O. As these types of complexes are noted secondary building units (SBU's) in the construction of metal-organic frameworks (MOF's), the significance of these interactions in stabilizing even larger, supramolecular structures, are noted.

  7. The effect of participation in an extended inquiry project on general chemistry student laboratory interactions, confidence, and process skills

    NASA Astrophysics Data System (ADS)

    Krystyniak, Rebecca A.

    2001-12-01

    This study explored the effect of participation by second-semester general chemistry students in an extended open-inquiry laboratory investigation on their use of science process skills and confidence in performing specific aspects of laboratory investigations. In addition, verbal interactions of a student lab team among team members and with their instructor over three open-inquiry laboratory sessions and two non-inquiry sessions were investigated. Instruments included the Test of Integrated Skills (TIPS), a 36-item multiple-choice instrument, and the Chemistry Laboratory Survey (CLS), a researcher co-designed 20-item 8-point instrument. Instruments were administered at the beginning and close of the semester to 157 second-semester general chemistry students at the two universities; students at only one university participated in open-inquiry activity. A MANCOVA was performed to investigate relationships among control and experimental students, TIPS, and CLS post-test scores. Covariates were TIPS and CLS pre-test scores and prior high school and college science experience. No significant relationships were found. Wilcoxen analyses indicated both groups showed increase in confidence; experimental-group students with below-average TIPS pre-test scores showed a significant increase in science process skills. Transcribed audio tapes of all laboratory-based verbal interactions were analyzed. Coding categories, developed using the constant comparison method, led to an inter-rater reliability of .96. During open-inquiry activities, the lab team interacted less often, sought less guidance from their instructor, and talked less about chemistry concepts than during non-inquiry activities. Evidence confirmed that students used science process skills and engaged in higher-order thinking during both types of activities. A four-student focus shared their experiences with open-inquiry activities, indicating that they enjoyed the experience, viewed it as worthwhile, and believed

  8. Intermolecular interaction and the extended wormlike chain conformation of chitin in NaOH/urea aqueous solution.

    PubMed

    Fang, Yan; Duan, Bo; Lu, Ang; Liu, Maili; Liu, Huili; Xu, Xiaojuan; Zhang, Lina

    2015-04-13

    The intra- and intermolecular interactions of chitin in NaOH/urea aqueous system were studied by a combination of NMR measurements (including (13)C NMR, (23)Na NMR, and (15)N NMR) and differential scanning calorimetry. The results revealed that the NaOH and chitin formed a hydrogen-bonded complex that was surrounded by the urea hydrates to form a sheath-like structure, leading to the good dissolution. The optimal concentration range, in which chitin was molecularly dispersed in NaOH/urea aqueous, was found to investigate the chain conformation in the dilute solution with a combination of static and dynamic light scattering. The weight-average molecular weight (Mw), radii of gyration (⟨Rg⟩z), and hydrodynamic radii (⟨Rh⟩z) values of chitin were determined, and the structure-sensitive parameter (ρ) and persistent length (Lp) were calculated to be >2.0 and ∼30 nm, respectively, suggesting an extended wormlike chain conformation. The visualized images from TEM, cryo-TEM, and AFM indicated that, chitin nanofibers were fabricated from the parallel aggregation of chitin chains in NaOH/urea system. This work would provide a theoretical guidance for constructing novel chitin-based nanomaterials via "bottom-up" method at the molecular level.

  9. Black-Box Description of Electron Correlation with the Spin-Extended Configuration Interaction Model: Implementation and Assessment.

    PubMed

    Tsuchimochi, Takashi; Ten-no, Seiichiro

    2016-04-12

    In our recent Communication (J. Chem. Phys. 2016, 144, 011101), we proposed Wick's theorem for nonorthogonal determinants and applied it to spin-extended configuration interaction with singles and doubles (ECISD) based on spin-projected unrestricted Hartree-Fock (SUHF), given that SUHF is a special case of nonorthogonal CI. It was shown that ECISD is accurate for bond-dissociation processes of several representative molecules. In the present work, we give a detailed derivation of ECISD and report an efficient implementation with two physically motivated preconditioning schemes in the generalized Davidson diagonalization for ECISD, whose Hamiltonian and overlap are not diagonal dominant due to SUHF's nonorthogonal character. In the first approach, we exploit the properties of corresponding pair orbitals and spin-projection operator and rotate the spin-projected CI basis so that the Hamiltonian is approximately diagonal. The second scheme is based on the normal ordered Hamiltonian, which suggests neglecting the expensive two-particle terms in the preconditioning. To enable frozen-core approximations in ECISD, core orbitals were introduced in SUHF. We also show the validity of our method with various numerical examples for static correlations, apart from the left-right correlation in bond-dissociation processes: the ground state energies of the Be isoelectronic series, excitation energies of representative small molecules, and spectroscopic constants of the strongly correlated BN singlet state. Several aspects of ECISD were studied.

  10. Search for the Skyrme-Hartree-Fock solutions for chiral rotation in N=75 isotones

    SciTech Connect

    Olbratowski, P.; Dobaczewski, J.; Dudek, J.

    2006-05-15

    A search for self-consistent solutions for the chiral rotational bands in the N=75 isotones {sup 130}Cs, {sup 132}La, {sup 134}Pr, and {sup 136}Pm is performed within the Skyrme-Hartree-Fock cranking approach using SKM* and SLy4 parametrizations. The dependence of the solutions on the time-odd contributions in the energy functional is studied. From among the four isotones considered, self-consistent chiral solutions are obtained only in {sup 132}La. The microscopic calculations are compared with the {sup 132}La experimental data and with results of a classical model that contains all the mechanisms underlying the chirality of the collective rotational motion. Strong similarities between the Hartree-Fock and classical model results are found. The suggestion formulated earlier by the authors that the chiral rotation cannot exist below a certain critical frequency is further illustrated and discussed, together with the microscopic origin of a transition from planar to chiral rotation in nuclei. We also formulate the separability rule by which the tilted-axis-cranking solutions can be inferred from three independent principal-axis-cranking solutions corresponding to three different axes of rotation.

  11. Uncertainty quantification of effective nuclear interactions

    SciTech Connect

    Pérez, R. Navarro; Amaro, J. E.; Arriola, E. Ruiz

    2016-03-02

    We give a brief review on the development of phenomenological NN interactions and the corresponding quanti cation of statistical uncertainties. We look into the uncertainty of effective interactions broadly used in mean eld calculations through the Skyrme parameters and effective eld theory counter-terms by estimating both statistical and systematic uncertainties stemming from the NN interaction. We also comment on the role played by different tting strategies on the light of recent developments.

  12. Properties of nuclei in the nobelium region studied within the covariant, Skyrme, and Gogny energy density functionals

    SciTech Connect

    Dobaczewski, J.; Afanasjev, A. V.; Bender, M.; Shi, Yue

    2015-07-29

    In this study, we calculate properties of the ground and excited states of nuclei in the nobelium region for proton and neutron numbers of 92 ≤ Z ≤ 104 and 144 ≤ N ≤ 156, respectively. We use three different energy-density-functional (EDF) approaches, based on covariant, Skyrme, and Gogny functionals, each with two different parameter sets. A comparative analysis of the results obtained for quasiparticle spectra, odd–even and two-particle mass staggering, and moments of inertia allows us to identify single-particle and shell effects that are characteristic to these different models and to illustrate possible systematic uncertainties related to using the EDF modelling.

  13. Remarks on the use of projected densities in the density-dependent part of Skyrme or Gogny functionals

    NASA Astrophysics Data System (ADS)

    Robledo, L. M.

    2010-06-01

    I discuss the inadequacy of the 'projected density' prescription to be used in density-dependent forces/functionals when calculations beyond mean field are pursued. The case of calculations aimed at the symmetry restoration of mean fields obtained with effective realistic forces of the Skyrme or Gogny type is considered in detail. It is shown that, at least for the restoration of spatial symmetries like rotations, translations or parity, the above prescription yields catastrophic results for the energy that drive the intrinsic wave-function to configurations with infinite deformation, thereby preventing its use both in projection after and before variation.

  14. Effects of air-sea interaction on extended-range prediction of geopotential height at 500 hPa over the northern extratropical region

    NASA Astrophysics Data System (ADS)

    Wang, Xujia; Zheng, Zhihai; Feng, Guolin

    2017-02-01

    The contribution of air-sea interaction on the extended-range prediction of geopotential height at 500 hPa in the northern extratropical region has been analyzed with a coupled model form Beijing Climate Center and its atmospheric components. Under the assumption of the perfect model, the extended-range prediction skill was evaluated by anomaly correlation coefficient (ACC), root mean square error (RMSE), and signal-to-noise ratio (SNR). The coupled model has a better prediction skill than its atmospheric model, especially, the air-sea interaction in July made a greater contribution for the improvement of prediction skill than other months. The prediction skill of the extratropical region in the coupled model reaches 16-18 days in all months, while the atmospheric model reaches 10-11 days in January, April, and July and only 7-8 days in October, indicating that the air-sea interaction can extend the prediction skill of the atmospheric model by about 1 week. The errors of both the coupled model and the atmospheric model reach saturation in about 20 days, suggesting that the predictable range is less than 3 weeks.

  15. Solution of the Skyrme Hartree Fock Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis. (V) HFODD(v2.08k)

    NASA Astrophysics Data System (ADS)

    Dobaczewski, J.; Olbratowski, P.

    2005-05-01

    We describe the new version (v2.08k) of the code HFODD which solves the nuclear Skyrme-Hartree-Fock or Skyrme-Hartree-Fock-Bogolyubov problem by using the Cartesian deformed harmonic-oscillator basis. Similarly as in the previous version (v2.08i), all symmetries can be broken, which allows for calculations with angular frequency and angular momentum tilted with respect to the mass distribution. In the new version, three minor errors have been corrected. New Version Program SummaryTitle of program: HFODD; version: 2.08k Catalogue number: ADVA Catalogue number of previous version: ADTO (Comput. Phys. Comm. 158 (2004) 158) Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVA Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Does the new version supersede the previous one: yes Computers on which this or another recent version has been tested: SG Power Challenge L, Pentium-II, Pentium-III, AMD-Athlon Operating systems under which the program has been tested: UNIX, LINUX, Windows-2000 Programming language used: Fortran Memory required to execute with typical data: 10M words No. of bits in a word: 64 No. of lines in distributed program, including test data, etc.: 52 631 No. of bytes in distributed program, including test data, etc.: 266 885 Distribution format:tar.gz Nature of physical problem: The nuclear mean-field and an analysis of its symmetries in realistic cases are the main ingredients of a description of nuclear states. Within the Local Density Approximation, or for a zero-range velocity-dependent Skyrme interaction, the nuclear mean-field is local and velocity dependent. The locality allows for an effective and fast solution of the self-consistent Hartree-Fock equations, even for heavy nuclei, and for various nucleonic ( n-particle n-hole) configurations, deformations, excitation energies, or angular momenta. Similar Local Density Approximation in the particle-particle channel, which is equivalent to using a zero

  16. On the possibility of extending the Noro-Frenkel generalized law of correspondent states to nonisotropic patchy interactions.

    PubMed

    Foffi, Giuseppe; Sciortino, Francesco

    2007-08-23

    Colloidal systems (and protein solutions) are often characterized by attractive interactions whose ranges are much smaller than the particle size. When this is the case and the interaction is spherical, systems obey a generalized law of correspondent states (GLCS), first proposed by Noro and Frenkel (Noro, M. G.; Frenkel, D. J. Chem. Phys. 2000, 113, 2941). The thermodynamic properties become insensitive to the details of the potential, depending only on the value of the second virial coefficient B2 and the density rho. The GLCS does not generically hold for the case of nonspherical potentials. In this Letter, we suggest that when particles interact via short-ranged small-angular amplitude patchy interactions (so that the condition of only one bond per patch is fulfilled), it is still possible to generalize the GLCS close to the liquid-gas critical point.

  17. Root–root interactions: extending our perspective to be more inclusive of the range of theories in ecology and agriculture using in-vivo analyses

    PubMed Central

    Faget, Marc; Nagel, Kerstin A.; Walter, Achim; Herrera, Juan M.; Jahnke, Siegfried; Schurr, Ulrich; Temperton, Vicky M.

    2013-01-01

    Background There is a large body of literature on competitive interactions among plants, but many studies have only focused on above-ground interactions and little is known about root–root dynamics between interacting plants. The perspective on possible mechanisms that explain the outcome of root–root interactions has recently been extended to include non-resource-driven mechanisms (as well as resource-driven mechanisms) of root competition and positive interactions such as facilitation. These approaches have often suffered from being static, partly due to the lack of appropriate methodologies for in-situ non-destructive root characterization. Scope Recent studies show that interactive effects of plant neighbourhood interactions follow non-linear and non-additive paths that are hard to explain. Common outcomes such as accumulation of roots mainly in the topsoil cannot be explained solely by competition theory but require a more inclusive theoretical, as well as an improved methodological framework. This will include the question of whether we can apply the same conceptual framework to crop versus natural species. Conclusions The development of non-invasive methods to dynamically study root–root interactions in vivo will provide the necessary tools to study a more inclusive conceptual framework for root–root interactions. By following the dynamics of root–root interactions through time in a whole range of scenarios and systems, using a wide variety of non-invasive methods, (such as fluorescent protein which now allows us to separately identify the roots of several individuals within soil), we will be much better equipped to answer some of the key questions in root physiology, ecology and agronomy. PMID:23378521

  18. In Silico, Experimental, Mechanistic Model for Extended-Release Felodipine Disposition Exhibiting Complex Absorption and a Highly Variable Food Interaction

    PubMed Central

    Kim, Sean H. J.; Jackson, Andre J.; Hunt, C. Anthony

    2014-01-01

    The objective of this study was to develop and explore new, in silico experimental methods for deciphering complex, highly variable absorption and food interaction pharmacokinetics observed for a modified-release drug product. Toward that aim, we constructed an executable software analog of study participants to whom product was administered orally. The analog is an object- and agent-oriented, discrete event system, which consists of grid spaces and event mechanisms that map abstractly to different physiological features and processes. Analog mechanisms were made sufficiently complicated to achieve prespecified similarity criteria. An equation-based gastrointestinal transit model with nonlinear mixed effects analysis provided a standard for comparison. Subject-specific parameterizations enabled each executed analog’s plasma profile to mimic features of the corresponding six individual pairs of subject plasma profiles. All achieved prespecified, quantitative similarity criteria, and outperformed the gastrointestinal transit model estimations. We observed important subject-specific interactions within the simulation and mechanistic differences between the two models. We hypothesize that mechanisms, events, and their causes occurring during simulations had counterparts within the food interaction study: they are working, evolvable, concrete theories of dynamic interactions occurring within individual subjects. The approach presented provides new, experimental strategies for unraveling the mechanistic basis of complex pharmacological interactions and observed variability. PMID:25268237

  19. In silico, experimental, mechanistic model for extended-release felodipine disposition exhibiting complex absorption and a highly variable food interaction.

    PubMed

    Kim, Sean H J; Jackson, Andre J; Hunt, C Anthony

    2014-01-01

    The objective of this study was to develop and explore new, in silico experimental methods for deciphering complex, highly variable absorption and food interaction pharmacokinetics observed for a modified-release drug product. Toward that aim, we constructed an executable software analog of study participants to whom product was administered orally. The analog is an object- and agent-oriented, discrete event system, which consists of grid spaces and event mechanisms that map abstractly to different physiological features and processes. Analog mechanisms were made sufficiently complicated to achieve prespecified similarity criteria. An equation-based gastrointestinal transit model with nonlinear mixed effects analysis provided a standard for comparison. Subject-specific parameterizations enabled each executed analog's plasma profile to mimic features of the corresponding six individual pairs of subject plasma profiles. All achieved prespecified, quantitative similarity criteria, and outperformed the gastrointestinal transit model estimations. We observed important subject-specific interactions within the simulation and mechanistic differences between the two models. We hypothesize that mechanisms, events, and their causes occurring during simulations had counterparts within the food interaction study: they are working, evolvable, concrete theories of dynamic interactions occurring within individual subjects. The approach presented provides new, experimental strategies for unraveling the mechanistic basis of complex pharmacological interactions and observed variability.

  20. Non-covalent interactions in extended systems described by the Effective Fragment Potential method: Theory and application to nucleobase oligomers

    PubMed Central

    Ghosh, Debashree; Kosenkov, Dmytro; Vanovschi, Vitalii; Williams, Christopher F.; Herbert, John M.; Gordon, Mark S.; Schmidt, Michael W.; Slipchenko, Lyudmila V.; Krylov, Anna I.

    2010-01-01

    The implementation of the Effective Fragment Potential (EFP) method within the Q-Chem electronic structure package is presented. The EFP method is used to study non-covalent π – π and hydrogen-bonding interactions in DNA strands. Since EFP is a computationally inexpensive alternative to high-level ab initio calculations, it is possible to go beyond the dimers of nucleic acid bases and to investigate the asymptotic behavior of different components of the total interaction energy. The calculations demonstrated that the dispersion energy is a leading component in π-stacked oligomers of all sizes. Exchange-repulsion energy also plays an important role. The contribution of polarization is small in these systems, whereas the magnitude of electrostatics varies. Pairwise fragment interactions (i.e., the sum of dimer binding energies) were found to be a good approximation for the oligomer energy. PMID:21067134

  1. Estimating spatial accessibility to facilities on the regional scale: an extended commuting-based interaction potential model

    PubMed Central

    2011-01-01

    Background There is growing interest in the study of the relationships between individual health-related behaviours (e.g. food intake and physical activity) and measurements of spatial accessibility to the associated facilities (e.g. food outlets and sport facilities). The aim of this study is to propose measurements of spatial accessibility to facilities on the regional scale, using aggregated data. We first used a potential accessibility model that partly makes it possible to overcome the limitations of the most frequently used indices such as the count of opportunities within a given neighbourhood. We then propose an extended model in order to take into account both home and work-based accessibility for a commuting population. Results Potential accessibility estimation provides a very different picture of the accessibility levels experienced by the population than the more classical "number of opportunities per census tract" index. The extended model for commuters increases the overall accessibility levels but this increase differs according to the urbanisation level. Strongest increases are observed in some rural municipalities with initial low accessibility levels. Distance to major urban poles seems to play an essential role. Conclusions Accessibility is a multi-dimensional concept that should integrate some aspects of travel behaviour. Our work supports the evidence that the choice of appropriate accessibility indices including both residential and non-residential environmental features is necessary. Such models have potential implications for providing relevant information to policy-makers in the field of public health. PMID:21219597

  2. The effects of the next-nearest-neighbour density-density interaction in the atomic limit of the extended Hubbard model.

    PubMed

    Kapcia, Konrad; Robaszkiewicz, Stanisław

    2011-03-16

    We have studied the extended Hubbard model in the atomic limit. The Hamiltonian analysed consists of the effective on-site interaction U and the intersite density-density interactions W(ij) (both nearest-neighbour and next-nearest-neighbour). The model can be considered as a simple effective model of charge ordered insulators. The phase diagrams and thermodynamic properties of this system have been determined within the variational approach, which treats the on-site interaction term exactly and the intersite interactions within the mean-field approximation. Our investigation of the general case taking into account for the first time the effects of longer-ranged density-density interaction (repulsive and attractive) as well as possible phase separations shows that, depending on the values of the interaction parameters and the electron concentration, the system can exhibit not only several homogeneous charge ordered (CO) phases, but also various phase separated states (CO-CO and CO-nonordered). One finds that the model considered exhibits very interesting multicritical behaviours and features, including bicritical, tricritical, and critical end points and isolated critical points.

  3. Coordinate-space solution of the Skyrme-Hartree-Fock- Bogolyubov equations within spherical symmetry. The program HFBRAD (v1.00)

    NASA Astrophysics Data System (ADS)

    Bennaceur, K.; Dobaczewski, J.

    2005-06-01

    We describe the first version (v1.00) of the code HFBRAD which solves the Skyrme-Hartree-Fock or Skyrme-Hartree-Fock-Bogolyubov equations in the coordinate representation with spherical symmetry. A realistic representation of the quasiparticle wave functions on the space lattice allows calculations to be performed up to the particle drip lines. Zero-range density-dependent interactions are used in the pairing channel. The pairing energy is calculated by either using a cut-off energy in the quasiparticle spectrum or the regularization scheme proposed by A. Bulgac and Y. Yu. Program summaryTitle of the program:HFBRAD (v1.00) Catalogue indentifier:ADVM Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVM Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Licensing provisions: none Computers on which the program has been tested: Pentium-III, Pentium-IV Operating systems: LINUX, Windows Programming language used:FORTRAN-95 Memory required to execute with typical data: 30 MBytes No. of bits in a word: The code is written with a type real and uses the intrinsic function selected_real_kind at the beginning of the code to ask for at least 12 significant digits. This can be easily modified by asking for more significant digits if the architecture of the computer can handle it. No. of processors used:1 Has the code been vectorized?:No No. of bytes in distributed program, including test data, etc.: 40 308 No. of lines in distributed program, including test data, etc.: 5370 Distribution format:tar.gz Nature of physical problem: For a self-consistent description of nuclear pair correlations, both the particle-hole (field) and particle-particle (pairing) channels of the nuclear mean field must be treated within a common approach, which is the Hartree-Fock-Bogolyubov theory. By expressing these fields in spatial coordinates one can obtain the best possible solutions of the problem; however, without assuming specific symmetries the

  4. Efficient proton acceleration and focusing by an ultraintense laser interacting with a parabolic double concave target with an extended rear

    SciTech Connect

    Bake, Muhammad Ali; Xie, Bai-Song; Aimidula, Aimierding; Wang, Hong-Yu

    2013-07-15

    A new scheme for acceleration and focusing of protons via an improved parabolic double concave target irradiated by an ultraintense laser pulse is proposed. When an intense laser pulse illuminates a concave target, the hot electrons are concentrated on the focal region of the rear cavity and they form a strong space-charge-separation field, which accelerates the protons. For a simple concave target, the proton energy spectrum becomes very broad outside the rear cavity because of transverse divergence of the electromagnetic fields. However, particle-in-cell simulations show that, when the concave target has an extended rear, the hot electrons along the wall surface induce a transverse focusing sheath field, resulting in a clear enhancement of proton focusing, which makes the lower proton energy spread, while, leads to a little reduction of the proton bunch peak energy.

  5. Diverse antimicrobial interactions of halophilic archaea and bacteria extend over geographical distances and cross the domain barrier.

    PubMed

    Atanasova, Nina S; Pietilä, Maija K; Oksanen, Hanna M

    2013-10-01

    The significance of antimicrobial substances, halocins, produced by halophilic archaea and bacteria thriving in hypersaline environments is relatively unknown. It is suggested that their production might increase species diversity and give transient competitive advances to the producer strain. Halocin production is considered to be common among halophilic archaea, but there is a lack of information about halocins produced by bacteria in highly saline environments. We studied the antimicrobial activity of 68 halophilic archaea and 22 bacteria isolated from numerous geographically distant hypersaline environments. Altogether 144 antimicrobial interactions were found between the strains and aside haloarchaea, halophilic bacteria from various genera were identified as halocin producers. Close to 80% of the interactions were detected between microorganisms from different genera and in few cases, even across the domain boundary. Several of the strains produced halocins with a wide inhibitory spectrum as has been observed before. Most of the antimicrobial interactions were found between strains from distant sampling sites indicating that hypersaline environments around the world have similar microorganisms with the potential to produce wide activity range antimicrobials.

  6. Properties of nuclei in the nobelium region studied within the covariant, Skyrme, and Gogny energy density functionals

    DOE PAGES

    Dobaczewski, J.; Afanasjev, A. V.; Bender, M.; ...

    2015-07-29

    In this study, we calculate properties of the ground and excited states of nuclei in the nobelium region for proton and neutron numbers of 92 ≤ Z ≤ 104 and 144 ≤ N ≤ 156, respectively. We use three different energy-density-functional (EDF) approaches, based on covariant, Skyrme, and Gogny functionals, each with two different parameter sets. A comparative analysis of the results obtained for quasiparticle spectra, odd–even and two-particle mass staggering, and moments of inertia allows us to identify single-particle and shell effects that are characteristic to these different models and to illustrate possible systematic uncertainties related to using themore » EDF modelling.« less

  7. Cocrystal Structures of Primed Side-Extending α-Ketoamide Inhibitors Reveal Novel Calpain-Inhibitor Aromatic Interactions

    SciTech Connect

    Qian,J.; Cuerrier, D.; Davies, P.; Li, Z.; Powers, J.; Campbell, R.

    2008-01-01

    Calpains are intracellular cysteine proteases that catalyze the cleavage of target proteins in response to Ca2+ signaling. When Ca2+ homeostasis is disrupted, calpain overactivation causes unregulated proteolysis, which can contribute to diseases such as postischemic injury and cataract formation. Potent calpain inhibitors exist, but of these many cross-react with other cysteine proteases and will need modification to specifically target calpain. Here, we present crystal structures of rat calpain 1 protease core ({mu}I-II) bound to two a-ketoamide-based calpain inhibitors containing adenyl and piperazyl primed-side extensions. An unexpected aromatic-stacking interaction is observed between the primed-side adenine moiety and the Trp298 side chain. This interaction increased the potency of the inhibitor toward {mu}I-II and heterodimeric m-calpain. Moreover, stacking orients the adenine such that it can be used as a scaffold for designing novel primed-side address regions, which could be incorporated into future inhibitors to enhance their calpain specificity.

  8. Chloride-selective electrodes based on "two-wall" aryl-extended calix[4]pyrroles: combining hydrogen bonds and anion-π interactions to achieve optimum performance.

    PubMed

    Sabek, Jad; Adriaenssens, Louis; Guinovart, Tomàs; Parra, Enrique J; Rius, F Xavier; Ballester, Pablo; Blondeau, Pascal

    2015-01-02

    The performance of chloride-selective electrodes based on "two-wall" aryl-extended calix[4]pyrroles and multiwall carbon nanotubes is presented. The calix[4]pyrrole receptors bear two phenyl groups at opposite meso-positions. When the meso-phenyl groups are decorated with strong electron-withdrawing substituents, attractive anion-π interactions may exist between the receptor's aromatic walls and the sandwiched anion. These anion-π interactions are shown to significantly affect the selectivity of the electrodes. Calix[4]pyrrole, bearing a p-nitro withdrawing group on each of the meso-phenyl rings, afforded sensors that display anti-Hofmeister behavior against the lipophilic salicylate and nitrate anions. Based on the experimental data, a series of principles that help in predicting the suitability of synthetic receptors for use as anion-specific ionophores is discussed. Finally, the sensors deliver excellent results in the direct detection of chloride in bodily fluids.

  9. Extending Parent–Child Interaction Therapy for Early Childhood Internalizing Problems: New Advances for an Overlooked Population

    PubMed Central

    Puliafico, Anthony C.; Kurtz, Steven M. S.; Pincus, Donna B.; Comer, Jonathan S.

    2014-01-01

    Although efficacious psychological treatments for internalizing disorders are now well established for school-aged children, until recently there have regrettably been limited empirical efforts to clarify indicated psychological intervention methods for the treatment of mood and anxiety disorders presenting in early childhood. Young children lack many of the developmental capacities required to effectively participate in established treatments for mood and anxiety problems presenting in older children, making simple downward extensions of these treatments for the management of preschool internalizing problems misguided. In recent years, a number of research groups have successfully adapted and modified parent–child interaction therapy (PCIT), originally developed to treat externalizing problems in young children, to treat various early internalizing problems with a set of neighboring protocols. As in traditional PCIT, these extensions target child symptoms by directly reshaping parent–child interaction patterns associated with the maintenance of symptoms. The present review outlines this emerging set of novel PCIT adaptations and modifications for mood and anxiety problems in young children and reviews preliminary evidence supporting their use. Specifically, we cover (a) PCIT for early separation anxiety disorder; (b) the PCIT-CALM (Coaching Approach behavior and Leading by Modeling) Program for the full range of early anxiety disorders; (c) the group Turtle Program for behavioral inhibition; and (d) the PCIT-ED (Emotional Development) Program for preschool depression. In addition, emerging PCIT-related protocols in need of empirical attention—such as the PCIT-SM (selective mutism) Program for young children with SM—are also considered. Implications of these protocols are discussed with regard to their unique potential to address the clinical needs of young children with internalizing problems. Obstacles to broad dissemination are addressed, and we consider

  10. Extending parent-child interaction therapy for early childhood internalizing problems: new advances for an overlooked population.

    PubMed

    Carpenter, Aubrey L; Puliafico, Anthony C; Kurtz, Steven M S; Pincus, Donna B; Comer, Jonathan S

    2014-12-01

    Although efficacious psychological treatments for internalizing disorders are now well established for school-aged children, until recently there have regrettably been limited empirical efforts to clarify indicated psychological intervention methods for the treatment of mood and anxiety disorders presenting in early childhood. Young children lack many of the developmental capacities required to effectively participate in established treatments for mood and anxiety problems presenting in older children, making simple downward extensions of these treatments for the management of preschool internalizing problems misguided. In recent years, a number of research groups have successfully adapted and modified parent-child interaction therapy (PCIT), originally developed to treat externalizing problems in young children, to treat various early internalizing problems with a set of neighboring protocols. As in traditional PCIT, these extensions target child symptoms by directly reshaping parent-child interaction patterns associated with the maintenance of symptoms. The present review outlines this emerging set of novel PCIT adaptations and modifications for mood and anxiety problems in young children and reviews preliminary evidence supporting their use. Specifically, we cover (a) PCIT for early separation anxiety disorder; (b) the PCIT-CALM (Coaching Approach behavior and Leading by Modeling) Program for the full range of early anxiety disorders; (c) the group Turtle Program for behavioral inhibition; and (d) the PCIT-ED (Emotional Development) Program for preschool depression. In addition, emerging PCIT-related protocols in need of empirical attention--such as the PCIT-SM (selective mutism) Program for young children with SM--are also considered. Implications of these protocols are discussed with regard to their unique potential to address the clinical needs of young children with internalizing problems. Obstacles to broad dissemination are addressed, and we consider

  11. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis.. (VII) HFODD (v2.49t): A new version of the program

    NASA Astrophysics Data System (ADS)

    Schunck, N.; Dobaczewski, J.; McDonnell, J.; Satuła, W.; Sheikh, J. A.; Staszczak, A.; Stoitsov, M.; Toivanen, P.

    2012-01-01

    format: tar.gz Programming language: FORTRAN-90 Computer: Intel Pentium-III, Intel Xeon, AMD-Athlon, AMD-Opteron, Cray XT4, Cray XT5 Operating system: UNIX, LINUX, Windows XP Has the code been vectorized or parallelized?: Yes, parallelized using MPI RAM: 10 Mwords Word size: The code is written in single-precision for the use on a 64-bit processor. The compiler option -r8 or +autodblpad (or equivalent) has to be used to promote all real and complex single-precision floating-point items to double precision when the code is used on a 32-bit machine. Classification: 17.22 Catalogue identifier of previous version: ADFL_v2_2 Journal reference of previous version: Comput. Phys. Comm. 180 (2009) 2361 External routines: The user must have access to the NAGLIB subroutine f02axe, or LAPACK subroutines zhpev, zhpevx, zheevr, or zheevd, which diagonalize complex hermitian matrices, the LAPACK subroutines dgetri and dgetrf which invert arbitrary real matrices, the LAPACK subroutines dsyevd, dsytrf and dsytri which compute eigenvalues and eigenfunctions of real symmetric matrices, the LINPACK subroutines zgedi and zgeco, which invert arbitrary complex matrices and calculate determinants, the BLAS routines dcopy, dscal, dgeem and dgemv for double-precision linear algebra and zcopy, zdscal, zgeem and zgemv for complex linear algebra, or provide another set of subroutines that can perform such tasks. The BLAS and LAPACK subroutines can be obtained from the Netlib Repository at the University of Tennessee, Knoxville: http://netlib2.cs.utk.edu/. Does the new version supersede the previous version?: Yes Nature of problem: The nuclear mean field and an analysis of its symmetries in realistic cases are the main ingredients of a description of nuclear states. Within the Local Density Approximation, or for a zero-range velocity-dependent Skyrme interaction, the nuclear mean field is local and velocity dependent. The locality allows for an effective and fast solution of the self

  12. Modified Iterative Extended Hueckel. 2: Application to the interaction of Na(+), Na(+)(aq.), Mg(+)-2(aq.) with adenine and thymine

    NASA Technical Reports Server (NTRS)

    Aronowitz, S.; Macelroy, R.; Chang, S.

    1980-01-01

    Modified Iterative Extended Hueckel, which includes explicit effective internuclear and electronic interactions, is applied to the study of the energetics of Na(+),Mg(+), Na(+) (aqueous), and Mg(+2) (aqueous) ions approaching various possible binding sites on adenine and thymine. Results for the adenine + ion and thymine + ion are in good qualitative agreement with ab initio work on analogous systems. Energy differences between competing sites are in excellent agreement. Hydration appears to be a critical factor in determining favorable binding sites. That the adenine Nl and N3 sites cannot displace a water molecule from the hydrated cation indicates that they are not favorable binding sites in aqueous media. Of those sites investigated, 04 was the most favorable binding site on the thymine for the bare Na(+). However, the 02 site was the most favorable binding site for either hydrated cation.

  13. The Vitamin B12-Dependent Photoreceptor AerR Relieves Photosystem Gene Repression by Extending the Interaction of CrtJ with Photosystem Promoters

    PubMed Central

    Fang, Mingxu

    2017-01-01

    ABSTRACT Purple nonsulfur bacteria adapt their physiology to a wide variety of environmental conditions often through the control of transcription. One of the main transcription factors involved in controlling expression of the Rhodobacter capsulatus photosystem is CrtJ, which functions as an aerobic repressor of photosystem genes. Recently, we reported that a vitamin B12 binding antirepressor of CrtJ called AerR is required for anaerobic expression of the photosystem. However, the mechanism whereby AerR regulates CrtJ activity is unclear. In this study, we used a combination of next-generation sequencing and biochemical methods to globally identify genes under control of CrtJ and the role of AerR in controlling this regulation. Our results indicate that CrtJ has a much larger regulon than previously known, with a surprising regulatory function under both aerobic and anaerobic photosynthetic growth conditions. A combination of in vivo chromatin immunoprecipitation-DNA sequencing (ChIP-seq) and ChIP-seq and exonuclease digestion (ChIP-exo) studies and in vitro biochemical studies demonstrate that AerR forms a 1:2 complex with CrtJ (AerR-CrtJ2) and that this complex binds to many promoters under photosynthetic conditions. The results of in vitro and in vivo DNA binding studies indicate that AerR-CrtJ2 anaerobically forms an extended interaction with the bacteriochlorophyll bchC promoter to relieve repression by CrtJ. This is contrasted by aerobic growth conditions where CrtJ alone functions as an aerobic repressor of bchC expression. These results indicate that the DNA binding activity of CrtJ is modified by interacting with AerR in a redox-regulated manner and that this interaction alters CrtJ’s function. PMID:28325764

  14. Quantitative analysis of the fusion cross sections using different microscopic nucleus-nucleus interactions

    NASA Astrophysics Data System (ADS)

    Adel, A.; Alharbi, T.

    2017-01-01

    The fusion cross sections for reactions involving medium and heavy nucleus-nucleus systems are investigated near and above the Coulomb barrier using the one-dimensional barrier penetration model. The microscopic nuclear interaction potential is computed by four methods, namely: the double-folding model based on a realistic density-dependent M3Y NN interaction with a finite-range exchange part, the Skyrme energy density functional in the semiclassical extended Thomas-Fermi approximation, the generalized Proximity potential, and the Akyüz-Winther interaction. The comparison between the calculated and the measured values of the fusion excitation functions indicates that the calculations of the DFM give quite satisfactory agreement with the experimental data, being much better than the other methods. New parameterized forms for the fusion barrier heights and positions are presented. Furthermore, the effects of deformation and orientation degrees of freedom on the distribution of the Coulomb barrier characteristics as well as the fusion cross sections are studied for the reactions 16 O + 70 Ge and 28 Si + 100 Mo. The calculated values of the total fusion cross sections are compared with coupled channel calculations using the code CCFULL and compared with the experimental data. Our results reveal that the inclusion of deformations and orientation degrees of freedom improves the comparison with the experimental data.

  15. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis. (IV) HFODD (v2.08i): a new version of the program

    NASA Astrophysics Data System (ADS)

    Dobaczewski, J.; Olbratowski, P.

    2004-04-01

    We describe the new version (v2.08i) of the code HFODD which solves the nuclear Skyrme-Hartree-Fock or Skyrme-Hartree-Fock-Bogolyubov problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, all symmetries can be broken, which allows for calculations with angular frequency and angular momentum tilted with respect to the mass distribution. The new version contains an interface to the LAPACK subroutine ZHPEVX. Program summaryTitle of the program:HFODD (v2.08i) Catalogue number: ADTO Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADTO Reference in CPC for earlier version of program: J. Dobaczewski and J. Dudek, Comput. Phys. Commun. 131 (2000) 164 (v1.75r) Catalogue number of previous version: ADML Licensing provisions: none Does the new version supersede the previous one: yes Computers on which the program has been tested: SG Power Challenge L, Pentium-II, Pentium-III, AMD-Athlon Operating systems: UNIX, LINUX, Windows-2000 Programming language used: FORTRAN-77 and FORTRAN-90 Memory required to execute with typical data: 10 Mwords No. of bits in a word: The code is written in single-precision for the use on a 64-bit processor. The compiler option -r8 or +autodblpad (or equivalent) has to be used to promote all real and complex single-precision floating-point items to double precision when the code is used on a 32-bit machine. Has the code been vectorised?: Yes No. of bytes in distributed program, including test data, etc.: 265352 No. of lines in distributed program: 52656 Distribution format: tar gzip file Nature of physical problem: The nuclear mean-field and an analysis of its symmetries in realistic cases are the main ingredients of a description of nuclear states. Within the Local Density Approximation, or for a zero-range velocity-dependent Skyrme interaction, the nuclear mean-field is local and velocity dependent. The locality allows for

  16. Particle-vibration coupling: Recent advances in microscopic calculations with the Skyrme Hamiltonian

    NASA Astrophysics Data System (ADS)

    Colò, G.; Baldo, M.; Bortignon, P. F.; Rizzo, D.; Bocchi, G.

    2016-11-01

    In this contribution, we report some recent progress in our understanding of particle-vibration coupling (PVC) in nuclei. In particular, we first review the formal development that has allowed some of us to deduce the PVC equations within the Green's functionmethod. Applications are then discussed, both in the case of single-particle states and giant resonances in magic nuclei. We also present a new model that extends the PVC ansatz and is meant to account for the complete low-lying spectra of odd nuclei.

  17. An Integrative Analysis of Preeclampsia Based on the Construction of an Extended Composite Network Featuring Protein-Protein Physical Interactions and Transcriptional Relationships

    PubMed Central

    Vaiman, Daniel; Miralles, Francisco

    2016-01-01

    Preeclampsia (PE) is a pregnancy disorder defined by hypertension and proteinuria. This disease remains a major cause of maternal and fetal morbidity and mortality. Defective placentation is generally described as being at the root of the disease. The characterization of the transcriptome signature of the preeclamptic placenta has allowed to identify differentially expressed genes (DEGs). However, we still lack a detailed knowledge on how these DEGs impact the function of the placenta. The tools of network biology offer a methodology to explore complex diseases at a systems level. In this study we performed a cross-platform meta-analysis of seven publically available gene expression datasets comparing non-pathological and preeclamptic placentas. Using the rank product algorithm we identified a total of 369 DEGs consistently modified in PE. The DEGs were used as seeds to build both an extended physical protein-protein interactions network and a transcription factors regulatory network. Topological and clustering analysis was conducted to analyze the connectivity properties of the networks. Finally both networks were merged into a composite network which presents an integrated view of the regulatory pathways involved in preeclampsia and the crosstalk between them. This network is a useful tool to explore the relationship between the DEGs and enable hypothesis generation for functional experimentation. PMID:27802351

  18. Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin

    PubMed Central

    Phillips-Jones, Mary K.; Channell, Guy; Kelsall, Claire J.; Hughes, Charlotte S.; Ashcroft, Alison E.; Patching, Simon G.; Dinu, Vlad; Gillis, Richard B.; Adams, Gary G.; Harding, Stephen E.

    2017-01-01

    VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regulated by the VanSARA two-component signal transduction system. The nature of the molecular ligand that is recognised by the VanSA sensory component has not hitherto been identified. Here we employ purified, intact and active VanSA membrane protein (henceforth referred to as VanS) in analytical ultracentrifugation experiments to study VanS oligomeric state and conformation in the absence and presence of vancomycin. A combination of sedimentation velocity and sedimentation equilibrium in the analytical ultracentrifuge (SEDFIT, SEDFIT-MSTAR and MULTISIG analysis) showed that VanS in the absence of the ligand is almost entirely monomeric (molar mass M = 45.7 kDa) in dilute aqueous solution with a trace amount of high molar mass material (M ~ 200 kDa). The sedimentation coefficient s suggests the monomer adopts an extended conformation in aqueous solution with an equivalent aspect ratio of ~(12 ± 2). In the presence of vancomycin over a 33% increase in the sedimentation coefficient is observed with the appearance of additional higher s components, demonstrating an interaction, an observation consistent with our circular dichroism measurements. The two possible causes of this increase in s – either a ligand induced dimerization and/or compaction of the monomer are considered.

  19. Extended antipaternalism

    PubMed Central

    Hansson, S

    2005-01-01

    Extended antipaternalism means the use of antipaternalist arguments to defend activities that harm (consenting) others. As an example, a smoker's right to smoke is often invoked in defence of the activities of tobacco companies. It can, however, be shown that antipaternalism in the proper sense does not imply such extended antipaternalism. We may therefore approve of Mill's antipaternalist principle (namely, that the only reason to interfere with someone's behaviour is to protect others from harm) without accepting activities that harm (consenting) others. This has immediate consequences for the ethics of public health. An antipaternalist need not refrain from interfering with activities such as the marketing of tobacco or heroin, boxing promotion, driving with unbelted passengers, or buying sex from "voluntary" prostitutes. PMID:15681674

  20. Fuel extender

    SciTech Connect

    Dorn, G.K.; Gilbert, H.A.

    1989-02-21

    An efficient and cost competitive fuel extender liquid is described for blending with lead-free gasoline as an additive thereto in a maximum amount of up to about 35% thereof with 65% by volume of the gasoline in a blended mixture wherein. The content of the extender in the resultant fuel as proportioned on the basis of its thus representative maximum content consists essentially of: naphtha X as represented by C/sub 4/, C/sub 5/ and C/sub 6/ hydrocarbons having a Reid vapor pressure of about 8.5 to 9.6 per ASTM, D323 test procedure and an initial distillation point of about 101/sup 0/F. and an end point of about 280/sup 0/F. within a range of about 10 to 25% by volume, about 3.8 to 6.0% by volume of anhydrous ethanol, a stabilizing amount of a water repellent of the class consisting of ethyl acetate and methyl isotubyl ketone; and about 4 to 10.5% by volume of aromatics benzene and toluene, of benzene and xylene or of benzene with toluene and xylene; the extender having a specific gravity substantially comparable with that of the lead-free gasoline to which it is to be added and having phase stability in the presence of water when mixed with the gasoline.

  1. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis.. (VI) HFODD (v2.40h): A new version of the program

    NASA Astrophysics Data System (ADS)

    Dobaczewski, J.; Satuła, W.; Carlsson, B. G.; Engel, J.; Olbratowski, P.; Powałowski, P.; Sadziak, M.; Sarich, J.; Schunck, N.; Staszczak, A.; Stoitsov, M.; Zalewski, M.; Zduńczuk, H.

    2009-11-01

    We describe the new version (v2.40h) of the code HFODD which solves the nuclear Skyrme-Hartree-Fock or Skyrme-Hartree-Fock-Bogolyubov problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we have implemented: (i) projection on good angular momentum (for the Hartree-Fock states), (ii) calculation of the GCM kernels, (iii) calculation of matrix elements of the Yukawa interaction, (iv) the BCS solutions for state-dependent pairing gaps, (v) the HFB solutions for broken simplex symmetry, (vi) calculation of Bohr deformation parameters, (vii) constraints on the Schiff moments and scalar multipole moments, (viii) the DT2h transformations and rotations of wave functions, (ix) quasiparticle blocking for the HFB solutions in odd and odd-odd nuclei, (x) the Broyden method to accelerate the convergence, (xi) the Lipkin-Nogami method to treat pairing correlations, (xii) the exact Coulomb exchange term, (xiii) several utility options, and we have corrected three insignificant errors. New version program summaryProgram title: HFODD (v2.40h) Catalogue identifier: ADFL_v2_2 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADFL_v2_2.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 79 618 No. of bytes in distributed program, including test data, etc.: 372 548 Distribution format: tar.gz Programming language: FORTRAN-77 and Fortran-90 Computer: Pentium-III, AMD-Athlon, AMD-Opteron Operating system: UNIX, LINUX, Windows XP Has the code been

  2. Sub-barrier fusion calculations for the neutron star crust using the microscopic Brueckner G -matrix and Skyrme energy density functionals

    NASA Astrophysics Data System (ADS)

    Rashdan, M.

    2015-05-01

    Sub-barrier fusion cross sections for reactions involving stable and very neutron-rich nuclei, which may be important in determining the composition and heating of the crust of accreting neutron stars, are calculated using internuclear potentials derived from the microscopic Brueckner G -matrix and Skyrme SKM* and SLy4 energy density functionals. Microscopic Skyrme-Hartree-Fock proton and neutron density distributions are used. No parameters have been fit to fusion data. Calculations are performed for the isotopic reactions 16O+16O,16O+24O,16O+28O,24O+24O,12C+16O,12C+24O , and 12C+12C , which are of great astrophysical importance for the understanding of the time scale and the nucleosynthesis during late stellar evolution. The coupling to the low lying excited states is considered through the ccfull code. I compare my results with the time-dependent-Hartree-Fock calculations and with the São Paulo model as well as the experimental data. I found a remarkable agreement with the fusion cross sections for stable nuclei.

  3. Allelic variants of the amylose extender mutation of maize demonstrate phenotypic variation in starch structure resulting from modified protein–protein interactions

    PubMed Central

    Liu, Fushan; Ahmed, Zaheer; Lee, Elizabeth A.; Donner, Elizabeth; Liu, Qiang; Ahmed, Regina; Morell, Matthew K.; Emes, Michael J.; Tetlow, Ian J.

    2012-01-01

    amylose extender (ae−) starches characteristically have modified starch granule morphology resulting from amylopectin with reduced branch frequency and longer glucan chains in clusters, caused by the loss of activity of the major starch branching enzyme (SBE), which in maize endosperm is SBEIIb. A recent study with ae− maize lacking the SBEIIb protein (termed ae1.1 herein) showed that novel protein–protein interactions between enzymes of starch biosynthesis in the amyloplast could explain the starch phenotype of the ae1.1 mutant. The present study examined an allelic variant of the ae− mutation, ae1.2, which expresses a catalytically inactive form of SBEIIb. The catalytically inactive SBEIIb in ae1.2 lacks a 28 amino acid peptide (Val272–Pro299) and is unable to bind to amylopectin. Analysis of starch from ae1.2 revealed altered granule morphology and physicochemical characteristics distinct from those of the ae1.1 mutant as well as the wild-type, including altered apparent amylose content and gelatinization properties. Starch from ae1.2 had fewer intermediate length glucan chains (degree of polymerization 16–20) than ae1.1. Biochemical analysis of ae1.2 showed that there were differences in the organization and assembly of protein complexes of starch biosynthetic enzymes in comparison with ae1.1 (and wild-type) amyloplasts, which were also reflected in the composition of starch granule-bound proteins. The formation of stromal protein complexes in the wild-type and ae1.2 was strongly enhanced by ATP, and broken by phosphatase treatment, indicating a role for protein phosphorylation in their assembly. Labelling experiments with [γ-32P]ATP showed that the inactive form of SBEIIb in ae1.2 was phosphorylated, both in the monomeric form and in association with starch synthase isoforms. Although the inactive SBEIIb was unable to bind starch directly, it was strongly associated with the starch granule, reinforcing the conclusion that its presence in the

  4. Axially deformed solution of the Skyrme-Hartree-Fock-Bogoliubov equations using the transformed harmonic oscillator basis (II) HFBTHO v2.00d: A new version of the program

    NASA Astrophysics Data System (ADS)

    Stoitsov, M. V.; Schunck, N.; Kortelainen, M.; Michel, N.; Nam, H.; Olsen, E.; Sarich, J.; Wild, S.

    2013-06-01

    of the transformed harmonic oscillator, which allows for an accurate description of deformation effects and pairing correlations in nuclei arbitrarily close to the particle drip lines. Solution method: The program uses the axial Transformed Harmonic Oscillator (THO) single- particle basis to expand quasi-particle wave functions. It iteratively diagonalizes the Hartree-Fock-Bogoliubov Hamiltonian based on generalized Skyrme-like energy densities and zero-range pairing interactions until a self-consistent solution is found. A previous version of the program was presented in: M.V. Stoitsov, J. Dobaczewski, W. Nazarewicz, P. Ring, Comput. Phys. Commun. 167 (2005) 43-63. Reasons for new version: Version 2.00d of HFBTHO provides a number of new options such as the optional breaking of reflection symmetry, the calculation of axial multipole moments, the finite temperature formalism for the HFB method, optimized multi-constraint calculations, the treatment of odd-even and odd-odd nuclei in the blocking approximation, and the framework for generalized energy density with arbitrary density-dependences. It is also the first version of HFBTHO to contain threading capabilities. Summary of revisions: The modified Broyden method has been implemented, Optional breaking of reflection symmetry has been implemented, The calculation of all axial multipole moments up to λ=8 has been implemented, The finite temperature formalism for the HFB method has been implemented, The linear constraint method based on the approximation of the Random Phase Approximation (RPA) matrix for multi-constraint calculations has been implemented, The blocking of quasi-particles in the Equal Filling Approximation (EFA) has been implemented, The framework for generalized energy density functionals with arbitrary density-dependence has been implemented, Shared memory parallelism via OpenMP pragmas has been implemented. Restrictions: Axial- and time-reversal symmetries are assumed. Unusual features: The user must

  5. An extended CCR5-ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions

    PubMed Central

    Kessler, Naama; Arshava, Boris; Naider, Fred; Scherf, Tali; Anglister, Jacob

    2015-01-01

    The chemokine receptor CCR5 serves as a co-receptor for the Human Immunodefficiency Virus type-1, HIV-1. The CCR5 N-terminal segment, the second extracellular loop (ECL2) and the transmembrane helices have been implicated in binding the envelope glycoprotein gp120. Peptides corresponding to the sequence of the putative ECL2 as well as peptides containing the ECL1 and ECL3 were found to inhibit HIV-1 infection. The aromatic residues in the C-terminal half of an ECL2 peptide were shown to interact with gp120. In the present study we determined that in aqueous buffer the segment Q188-Q194 in an elongated ECL2 peptide (R168 to K197) forms an amphiphilic helix, which corresponds to the beginning of the fifth transmembrane helix in the crystal structure of CCR5. Two dimensional Saturation Transfer Difference NMR spectroscopy and dynamic filtering studies revealed the involvement of Y187, F189, W190 and F193 of the helical segment, in the interaction with gp120. The crystal structure of CCR5 shows that the aromatic side chains of F189, W190 and F193 point away from the binding pocket and interact with the membrane or with an adjacent CCR5 molecule and therefore, could not interact with gp120 in the intact CCR5 receptor. We conclude that these three aromatic residues of ECL2 peptides interact with gp120 through hydrophobic interactions not representative of the interactions of the intact CCR5 receptor. The HIV-1 inhibition by ECL2 peptides as well as by ECL1 and ECL3 peptides and peptides corresponding to ECL2 of CXCR4, which serves as an alternative HIV-1 co-receptor, suggests that there is a hydrophobic surface in the envelope spike that could be a target for HIV-1 entry inhibitors. PMID:25703038

  6. Revisting the Density Matrix Expansion with Regulated Chiral Interactions

    NASA Astrophysics Data System (ADS)

    Dyhdalo, Alexander; Furnstahl, Richard; Bogner, Scott; Schunck, Nicolas; Navarro Perez, Rodrigo

    2016-09-01

    The density matrix expansion provides a general way to map microscopic interactions to a local functional. Previous density matrix expansion formulations added unregulated chiral long-range potentials to a Skyrme-type functional, which accounted for the short-range contributions. We implement the expansion with new coordinate space regulators using the regulator cutoff as a tool to adiabatically turn on finite-range pion interactions. We discuss `smoking guns' for correct inclusion of 3-body forces, which are implemented in a normal-ordering prescription, and compare to ab initio calculations.

  7. Zasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with α-Actinin via an Extended PDZ Domain

    PubMed Central

    Liao, Kuo An; González-Morales, Nicanor

    2016-01-01

    Z-discs are organizing centers that establish and maintain myofibril structure and function. Important Z-disc proteins are α-actinin, which cross-links actin thin filaments at the Z-disc and Zasp PDZ domain proteins, which directly interact with α-actinin. Here we investigate the biochemical and genetic nature of this interaction in more detail. Zasp52 is the major Drosophila Zasp PDZ domain protein, and is required for myofibril assembly and maintenance. We show by in vitro biochemistry that the PDZ domain plus a C-terminal extension is the only area of Zasp52 involved in the interaction with α-actinin. In addition, site-directed mutagenesis of 5 amino acid residues in the N-terminal part of the PDZ domain, within the PWGFRL motif, abolish binding to α-actinin, demonstrating the importance of this motif for α-actinin binding. Rescue assays of a novel Zasp52 allele demonstrate the crucial importance of the PDZ domain for Zasp52 function. Flight assays also show that a Zasp52 mutant suppresses the α-actinin mutant phenotype, indicating that both proteins are core structural Z-disc proteins required for optimal Z-disc function. PMID:27783625

  8. Solution of the Skyrme-Hartree-Fock-Bogolyubov equations in the Cartesian deformed harmonic-oscillator basis. (VII) HFODD (v2.49t): A new version of the program

    SciTech Connect

    Schunck, Nicolas F; McDonnell, J.; Sheikh, J. A.; Staszczak, A.; Stoitsov, Mario; Dobaczewski, J.; Toivanen, P.

    2012-01-01

    We describe the new version (v2.49t) of the code HFODD which solves the nuclear Skyrme Hartree-Fock (HF) or Skyrme Hartree-Fock-Bogolyubov (HFB) problem by using the Cartesian deformed harmonic-oscillator basis. In the new version, we have implemented the following physics features: (i) the isospin mixing and projection, (ii) the finite temperature formalism for the HFB and HF+BCS methods, (iii) the Lipkin translational energy correction method, (iv) the calculation of the shell correction. A number of specific numerical methods have also been implemented in order to deal with large-scale multi-constraint calculations and hardware limitations: (i) the two-basis method for the HFB method, (ii) the Augmented Lagrangian Method (ALM) for multi-constraint calculations, (iii) the linear constraint method based on the approximation of the RPA matrix for multi-constraint calculations, (iv) an interface with the axial and parity-conserving Skyrme-HFB code HFBTHO, (v) the mixing of the HF or HFB matrix elements instead of the HF fields. Special care has been paid to using the code on massively parallel leadership class computers. For this purpose, the following features are now available with this version: (i) the Message Passing Interface (MPI) framework, (ii) scalable input data routines, (iii) multi-threading via OpenMP pragmas, (iv) parallel diagonalization of the HFB matrix in the simplex breaking case using the ScaLAPACK library. Finally, several little significant errors of the previous published version were corrected.

  9. Thermodynamic characterization of halide-π interactions in solution using "two-wall" aryl extended calix[4]pyrroles as model system.

    PubMed

    Adriaenssens, Louis; Gil-Ramírez, Guzmán; Frontera, Antonio; Quiñonero, David; Escudero-Adán, Eduardo C; Ballester, Pablo

    2014-02-26

    Herein, we report our latest experimental investigations of halide-π interactions in solution. We base this research on the thermodynamic characterization of a series of 1:1 complexes formed between halides (Cl(-), Br(-), and I(-)) and several α,α-isomers of "two-wall" calix[4]pyrrole receptors bearing two six-membered aromatic rings in opposed meso positions. The installed aromatic systems feature a broad range of electron density as indicated by the calculated values for their electrostatic surface potentials at the center of the rings. We show that a correlation exists between the electronic nature of the aromatic walls and the thermodynamic stability of the X(-)⊂receptor complexes. We give evidence for the existence of both repulsive and attractive interactions between π systems and halide anions in solution (between 1 and -1 kcal/mol). We dissect the measured free energies of binding for chloride and bromide with the receptor series into their enthalpic and entropic thermodynamic quantities. In acetonitrile solution, the binding enthalpy values remain almost constant throughout the receptor series, and the differences in free energies are provoked exclusively by changes in the entropic term of the binding processes. Most likely, this unexpected behavior is owed to strong solvation effects that make up important components of the measured magnitudes for the enthalpies and entropies of binding. The use of chloroform, a much less polar solvent, limits the impact of solvation effects revealing the expected existence of a parallel trend between free energies and enthalpies of binding. This result indicates that halide-π interactions in organic solvents are mainly driven by enthalpy. However, the typical paradigm of enthalpy-entropy compensation is still not observed in this less polar solvent.

  10. The Bactofilin Cytoskeleton Protein BacM of Myxococcus xanthus Forms an Extended β-Sheet Structure Likely Mediated by Hydrophobic Interactions

    PubMed Central

    Xie, Kefang; Engelhardt, Harald; Bosch, Jürgen; Hoiczyk, Egbert

    2015-01-01

    Bactofilins are novel cytoskeleton proteins that are widespread in Gram-negative bacteria. Myxococcus xanthus, an important predatory soil bacterium, possesses four bactofilins of which one, BacM (Mxan_7475) plays an important role in cell shape maintenance. Electron and fluorescence light microscopy, as well as studies using over-expressed, purified BacM, indicate that this protein polymerizes in vivo and in vitro into ~3 nm wide filaments that further associate into higher ordered fibers of about 10 nm. Here we use a multipronged approach combining secondary structure determination, molecular modeling, biochemistry, and genetics to identify and characterize critical molecular elements that enable BacM to polymerize. Our results indicate that the bactofilin-determining domain DUF583 folds into an extended β-sheet structure, and we hypothesize a left-handed β-helix with polymerization into 3 nm filaments primarily via patches of hydrophobic amino acid residues. These patches form the interface allowing head-to-tail polymerization during filament formation. Biochemical analyses of these processes show that folding and polymerization occur across a wide variety of conditions and even in the presence of chaotropic agents such as one molar urea. Together, these data suggest that bactofilins are comprised of a structure unique to cytoskeleton proteins, which enables robust polymerization. PMID:25803609

  11. Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7

    PubMed Central

    Nguyen, Thuy T.; Caito, Samuel W.; Zackert, William E.; West, James D.; Zhu, Shijun

    2016-01-01

    Isoketals (IsoKs) are highly reactive γ-ketoaldehyde products of lipid peroxidation that covalently adduct lysine side chains in proteins, impairing their function. Using C. elegans as a model organism, we sought to test the hypothesis that IsoKs contribute to molecular aging through adduction and inactivation of specific protein targets, and that this process can be abrogated using salicylamine (SA), a selective IsoK scavenger. Treatment with SA extends adult nematode longevity by nearly 56% and prevents multiple deleterious age-related biochemical and functional changes. Testing of a variety of molecular targets for SA's action revealed the sirtuin SIR-2.1 as the leading candidate. When SA was administered to a SIR-2.1 knockout strain, the effects on lifespan and healthspan extension were abolished. The SIR-2.1-dependent effects of SA were not mediated by large changes in gene expression programs or by significant changes in mitochondrial function. However, expression array analysis did show SA-dependent regulation of the transcription factor ets-7 and associated genes. In ets-7 knockout worms, SA's longevity effects were abolished, similar to sir-2.1 knockouts. However, SA dose-dependently increases ets-7 mRNA levels in non-functional SIR-2.1 mutant, suggesting that both are necessary for SA's complete lifespan and healthspan extension. PMID:27514077

  12. An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase

    PubMed Central

    Golden, Emily; Yu, Li-Juan; Meilleur, Flora; Blakeley, Matthew P.; Duff, Anthony P.; Karton, Amir; Vrielink, Alice

    2017-01-01

    The protein microenvironment surrounding the flavin cofactor in flavoenzymes is key to the efficiency and diversity of reactions catalysed by this class of enzymes. X-ray diffraction structures of oxidoreductase flavoenzymes have revealed recurrent features which facilitate catalysis, such as a hydrogen bond between a main chain nitrogen atom and the flavin redox center (N5). A neutron diffraction study of cholesterol oxidase has revealed an unusual elongated main chain nitrogen to hydrogen bond distance positioning the hydrogen atom towards the flavin N5 reactive center. Investigation of the structural features which could cause such an unusual occurrence revealed a positively charged lysine side chain, conserved in other flavin mediated oxidoreductases, in a second shell away from the FAD cofactor acting to polarize the peptide bond through interaction with the carbonyl oxygen atom. Double-hybrid density functional theory calculations confirm that this electrostatic arrangement affects the N-H bond length in the region of the flavin reactive center. We propose a novel second-order partial-charge interaction network which enables the correct orientation of the hydride receiving orbital of N5. The implications of these observations for flavin mediated redox chemistry are discussed. PMID:28098177

  13. An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase

    NASA Astrophysics Data System (ADS)

    Golden, Emily; Yu, Li-Juan; Meilleur, Flora; Blakeley, Matthew P.; Duff, Anthony P.; Karton, Amir; Vrielink, Alice

    2017-01-01

    The protein microenvironment surrounding the flavin cofactor in flavoenzymes is key to the efficiency and diversity of reactions catalysed by this class of enzymes. X-ray diffraction structures of oxidoreductase flavoenzymes have revealed recurrent features which facilitate catalysis, such as a hydrogen bond between a main chain nitrogen atom and the flavin redox center (N5). A neutron diffraction study of cholesterol oxidase has revealed an unusual elongated main chain nitrogen to hydrogen bond distance positioning the hydrogen atom towards the flavin N5 reactive center. Investigation of the structural features which could cause such an unusual occurrence revealed a positively charged lysine side chain, conserved in other flavin mediated oxidoreductases, in a second shell away from the FAD cofactor acting to polarize the peptide bond through interaction with the carbonyl oxygen atom. Double-hybrid density functional theory calculations confirm that this electrostatic arrangement affects the N-H bond length in the region of the flavin reactive center. We propose a novel second-order partial-charge interaction network which enables the correct orientation of the hydride receiving orbital of N5. The implications of these observations for flavin mediated redox chemistry are discussed.

  14. Interaction of oxyimino beta-lactams with a class C beta-lactamase and a mutant with a spectrum extended to beta-lactams.

    PubMed Central

    Nukaga, M; Tsukamoto, K; Yamaguchi, H; Sawai, T

    1994-01-01

    The class C beta-lactamase of Citrobacter freundii GN346 is a typical cephalosporinase comprising 361 amino acids, and substitution of the glutamic acid at position 219 in the enzyme by lysine was previously shown to broaden its substrate spectrum to oxyimino beta-lactams (K. Tsukamoto, R. Ohno, and T. Sawai, J. Bacteriol. 172:4348-4351, 1990). To clarify this spectrum extension from the kinetic point of view, the interactions of cefuroxime, ceftazidime, and aztreonam with the wild-type and mutant enzymes were analyzed. In addition to aztreonam, known as a progressive inhibitor of class C beta-lactamases, cefuroxime and ceftazidime were found to act as progressive inhibitors of the wild-type enzyme. On the other hand, only aztreonam showed weak progressive inhibition of the mutant enzyme. On the basis of kinetic parameters, a minimum scheme for interaction of the oxyimino beta-lactams with the wild-type enzyme was proposed, and the rate-limiting step of the hydrolysis of unfavorable substrates was indicated to be conversion of the stable acyl-enzyme intermediate to the unstable intermediate. In aztreonam hydrolysis by the mutant enzyme, the reaction rate at the rate-limiting step was 2,000 times that of the wild-type enzyme. These results indicate that the mutation at position 219 disturbs the stabilization of the stable intermediate. PMID:8092840

  15. Isopiestic Determination of the Osmotic and Activity Coefficients of NaCl + SrCl2 + H2O at 298.15 K, and Representation with an Extended Ion-Interaction Model

    SciTech Connect

    Clegg, S L; Rard, J A; Miller, D G

    2004-11-09

    Isopiestic vapor-pressure measurements were made at 298.15 K for aqueous NaCl + SrCl{sub 2} solutions, using NaCl(aq) as the reference standard. The measurements for these ternary solutions were made at NaCl ionic strength fractions of y{sub 1} = 0.17066, 0.47366, and 0.82682 for the water activity range 0.9835 {ge} a{sub w} {ge} 0.8710. Our results, and those from two previous isopiestic studies, were combined and used with previously determined parameters for NaCl(aq) and those for SrCl{sub 2}(aq) determined here to evaluate the mixing parameters{sup S}{Theta}{sub Na,Sr} = (0.0562 {+-} 0.0007) kg {center_dot} mol{sup -1} and {Psi}{sub Na,Sr,Cl} = -(0.00705 {+-} 0.00017) kg{sup 2} {center_dot} mol{sup -2} for an extended form of Pitzer's ion-interaction model. These model parameters are valid for ionic strengths of I {le} 7.0 mol {center_dot} kg{sup -1}, where higher-order electrostatic effects have been included in the mixture model. If the fitting range is extended to the saturated solution molalities, then {sup S}{Theta}{sub Na,Sr} = (0.07885 {+-} 0.00195) kg {center_dot} mol{sup -1} and {Psi}{sub Na,Sr,Cl} = -(0.01230 {+-} 0.00033) kg{sup 2} {center_dot} mol{sup -2}. The extended ion-interaction model parameters obtained from available isopiestic data for SrCl{sub 2}(aq) at 298.15 K yield recommended values of the water activities and osmotic and activity coefficients.

  16. Extended Ewald summation technique

    NASA Astrophysics Data System (ADS)

    Kylänpää, Ilkka; Räsänen, Esa

    2016-09-01

    We present a technique to improve the accuracy and to reduce the computational labor in the calculation of long-range interactions in systems with periodic boundary conditions. We extend the well-known Ewald method by using a linear combination of screening Gaussian charge distributions instead of only one. This enables us to find faster converging real-space and reciprocal space summations. The combined simplicity and efficiency of our method is demonstrated, and the scheme is readily applicable to large-scale periodic simulations, classical as well as quantum. Moreover, apart from the required a priori optimization the method is straightforward to include in most routines based on the Ewald method within, e.g., density-functional, molecular dynamics, and quantum Monte Carlo calculations.

  17. Mean-Field Approach with M3Y-TYPE Interaction

    NASA Astrophysics Data System (ADS)

    Nakada, H.

    2004-10-01

    M3Y-type interactions are developed and applied to mean-field calculations. By comparing results of an M3Y-type interaction on the uniform nuclear matter with those of the Skyrme and the Gogny interactions, we find a remarkable difference in the spin-isospin properties, to which the one-pion-exchange potential gives significant contribution. Correlating to variation of the shell structure, these spin-isospin properties play a certain role in the new magic numbers near drip lines such as N = 16 and N = 32.

  18. Extended interaction of β1 integrin subunit-deficient cells (GD25) with surfaces modified with fibronectin-derived peptides: culture optimization, adhesion and cytokine panel studies

    PubMed Central

    Waldeck, Heather; Kao, Weiyuan John

    2008-01-01

    The modification of biomaterials with extracellular matrix-mimicking factors to influence the cellular response through mainly integrin-mediated signaling is a common technique. The inherent limitations of antibody-inhibition studies necessitate the use of complementary methods to block integrin function to confirm cell–surface interaction. In this study, we employed a β1 integrin-deficient cell line, GD25, to investigate the role of β1 subunit in cell adhesion and subsequent cytokine (granulocyte macrophage colony stimulating factor, interleukin (IL)-1α, IL-1β, IL-6, granulocyte macrophage colony stimulating factor -1, regulated upon activation, normal T-cell expressed, and secreted, tumor necrosis factor-α) release kinetics in the presence of tissue culture polystyrene (TCPS) and semi-interpenetrating polymer networks (sIPN) modified with fibronectin (FN)-mimic peptides (RGD, PHSRN). Culture conditions (i.e. seeding density, medium, serum supplementation) were optimized for long-term observation. Differences in cell adhesion, cell viability and cytokine release behavior were dependent on the presence of the β1 integrin subunit, FN, sIPN cast method and peptide identity. By comparing two complementary techniques for assaying integrin function, we observed both similarities (i.e. decreased adhesion to FN-absorbed TCPS and increased IL-1β release at 96 h) and differences (i.e. no difference in adhesion or IL-1β release in the presence of sIPN surfaces) when the function of the β1 subunit was blocked in cell adhesion and signaling in the presence of biomaterials. PMID:18514047

  19. Magnetic Interactions in the Copper Complex (L-Aspartato)(1,10-phenanthroline)copper(II) Hydrate. An Exchange-Coupled Extended System with Two Dissimilar Copper Ions.

    PubMed

    Brondino, Carlos D.; Calvo, Rafael; Atria, Ana María; Spodine, Evgenia; Nascimento, Otaciro R.; Peña, Octavio

    1997-07-02

    We report EPR measurements in single-crystal samples at the microwave frequencies 9.8 and 34.3 GHz and magnetic susceptibility measurements in polycrystalline samples for the ternary complex of copper with aspartic acid and phenanthroline, (L-aspartato)(1,10-phenanthroline)copper(II) hydrate. The crystal lattice of this compound is composed of two dissimilar copper ions identified as Cu(A) and Cu(B), which are in two types of copper chains called A and B, respectively, running parallel to the b crystal axis. The copper ions in the A chains are connected by the aspartic acid molecule, and those in the B chains by a chemical path that involves a carboxylate bridge and a hydrogen bond. Both chains are held together by a complex network of hydrogen bonds and by hydrophobic interactions between aromatic amines. Magnetic susceptibility data indicate a Curie-Weiss behavior in the studied temperature range (2-300 K). The EPR spectra at 9.8 GHz display a single exchange collapsed resonance for any magnetic field orientation, in the so-called strong exchange regime. Those at 34.3 GHz are within the so-called weak exchange regime and display two resonances which belong to each type of copper ion chain. The decoupling of the spectra at 34.3 GHz using a theory based on Anderson's model for the case of two weakly exchange coupled spins S = (1)/(2) allows one to obtain the angular variation of the squares of the g-factor and the peak-to-peak line width of each resonance. This model also allows one to evaluate the exchange parameter |J(AB)/k| = 2.7(6) mK associated with the chemical path connecting dissimilar copper ions. The line width data obtained for each component of the spectra at 34.3 GHz are analyzed in terms of a model based on Kubo and Tomita's theory, to obtain the exchange parameters |J(A)/k| = 0.77(2) K and |J(B)/k| = 1.44(2) K associated with the chemical paths connecting the similar copper ions of types A and B, respectively.

  20. Rice phytochrome-interacting factor protein OsPIFff14 represses OsDREB1B gene expression through an extended N-box and interacts preferentially with the active form of phytochrome B

    Technology Transfer Automated Retrieval System (TEKTRAN)

    DREB1/CBF genes, known as major regulators of plant stress responses, are rapidly and transiently induced by low temperatures. Using a Yeast one Hybrid screening, we identified a putative Phytochrome-Interacting bHLH Factor (OsPIF14), as binding to the OsDREB1B promoter. bHLH proteins are able to bi...

  1. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy*

    PubMed Central

    Olsvik, Hallvard L.; Lamark, Trond; Takagi, Kenji; Larsen, Kenneth Bowitz; Evjen, Gry; Øvervatn, Aud; Mizushima, Tsunehiro; Johansen, Terje

    2015-01-01

    FYCO1 (FYVE and coiled-coil protein 1) is a transport adaptor that binds to phosphatidylinositol 3-phosphate, to Rab7, and to LC3 (microtubule-associated protein 1 light chain 3) to mediate transport of late endosomes and autophagosomes along microtubules in the plus end direction. We have previously shown that FYCO1 binds to LC3B via a 19-amino acid sequence containing a putative core LC3-interacting region (LIR) motif. Here, we show that FYCO1 preferentially binds to LC3A and -B. By peptide array-based two-dimensional mutational scans of the binding to LC3B, we found FYCO1 to contain a C-terminally extended LIR domain. We determined the crystal structure of a complex between a 13-amino acid LIR peptide from FYCO1 and LC3B at 1.53 Å resolution. By combining the structural information with mutational analyses, both the basis for the C-terminally extended LIR and the specificity for LC3A/B binding were revealed. FYCO1 contains a 9-amino acid-long F-type LIR motif. In addition to the canonical aromatic residue at position 1 and the hydrophobic residue at position 3, an acidic residue and a hydrophobic residue at positions 8 and 9, respectively, are important for efficient binding to LC3B explaining the C-terminal extension. The specificity for binding to LC3A/B is due to the interaction between Asp1285 in FYCO1 and His57 in LC3B. To address the functional significance of the LIR motif of FYCO1, we generated FYCO1 knock-out cells that subsequently were reconstituted with GFP-FYCO1 WT and LIR mutant constructs. Our data show that FYCO1 requires a functional LIR motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected. PMID:26468287

  2. Rice phytochrome-interacting factor protein OsPIF14 represses OsDREB1B gene expression through an extended N-box and interacts preferentially with the active form of Phytochrome B

    PubMed Central

    Cordeiro, André M.; Figueiredo, Duarte D.; Tepperman, James; Borba, Ana Rita; Lourenço, Tiago; Abreu, Isabel A.; Ouwerkerk, Pieter B.F.; Quail, Peter H.; Oliveira, M. Margarida; Saibo, Nelson J. M.

    2016-01-01

    DREB1/CBF genes, known as major regulators of plant stress responses, are rapidly and transiently induced by low temperatures. Using a Yeast one Hybrid screening, we identified a putative Phytochrome-Interacting bHLH Factor (OsPIF14), as binding to the OsDREB1B promoter. bHLH proteins are able to bind to hexameric E-box (CANNTG) or N-box (CACG(A/C)G) motifs, depending on transcriptional activity. We have shown that OsPIF14 binds to the OsDREB1B promoter through two N-boxes and that the flanking regions of the hexameric core are essential for protein-DNA interaction and stability. We also showed that OsPIF14 down-regulates OsDREB1B gene expression in rice protoplasts, corroborating the OsPIF14 repressor activity observed in the transactivation assays using Arabidopsis protoplasts. In addition, we showed that OsPIF14 is indeed a Phytochrome Interacting Factor, which preferentially binds to the active form (Pfr) of rice phytochrome B. This raises the possibility that OsPIF14 activity might be modulated by light. However, we did not observe any regulation of the OsDREB1B gene expression by light under control conditions. Moreover, OsPIF14 gene expression was shown to be modulated by different treatments, such as drought, salt, cold and ABA. Interestingly, OsPIF14 showed also a specific cold-induced alternative splicing. All together, these results suggest the possibility that OsPIF14 is involved in cross-talk between light and stress signaling through interaction with the OsDREB1B promoter. Although in the absence of stress, OsDREB1B gene expression was not regulated by light, given previous reports, it remains possible that OsPIF14 has a role in light modulation of stress responses. PMID:26732823

  3. Rice phytochrome-interacting factor protein OsPIF14 represses OsDREB1B gene expression through an extended N-box and interacts preferentially with the active form of phytochrome B

    DOE PAGES

    Cordeiro, André M.; Figueiredo, Duarte D.; Tepperman, James; ...

    2015-12-28

    DREB1/CBF genes, known as major regulators of plant stress responses, are rapidly and transiently induced by low temperatures. Using a yeast one-hybrid screening, we identified a putative Phytochrome-Interacting bHLH Factor (OsPIF14), as binding to the OsDREB1B promoter. bHLH proteins are able to bind to hexameric E-box (CANNTG) or N-box (CACG(A/C)G) motifs, depending on transcriptional activity. We have shown that OsPIF14 binds to the OsDREB1B promoter through two N-boxes and that the flanking regions of the hexameric core are essential for protein–DNA interaction and stability. We also showed that OsPIF14 down-regulates OsDREB1B gene expression in rice protoplasts, corroborating the OsPIF14 repressormore » activity observed in the transactivation assays using Arabidopsis protoplasts. Additionally, we showed that OsPIF14 is indeed a phytochrome interacting factor, which preferentially binds to the active form (Pfr) of rice phytochrome B. This raises the possibility that OsPIF14 activity might be modulated by light. However, we did not observe any regulation of the OsDREB1B gene expression by light under control conditions. Moreover, OsPIF14 gene expression was shown to be modulated by different treatments, such as drought, salt, cold and ABA. Interestingly, OsPIF14 showed also a specific cold-induced alternative splicing. Our results suggest the possibility that OsPIF14 is involved in cross-talk between light and stress signaling through interaction with the OsDREB1B promoter. Finally, although in the absence of stress, OsDREB1B gene expression was not regulated by light, given previous reports, it remains possible that OsPIF14 has a role in light modulation of stress responses.« less

  4. Rice phytochrome-interacting factor protein OsPIF14 represses OsDREB1B gene expression through an extended N-box and interacts preferentially with the active form of phytochrome B.

    PubMed

    Cordeiro, André M; Figueiredo, Duarte D; Tepperman, James; Borba, Ana Rita; Lourenço, Tiago; Abreu, Isabel A; Ouwerkerk, Pieter B F; Quail, Peter H; Margarida Oliveira, M; Saibo, Nelson J M

    2016-02-01

    DREB1/CBF genes, known as major regulators of plant stress responses, are rapidly and transiently induced by low temperatures. Using a yeast one-hybrid screening, we identified a putative Phytochrome-Interacting bHLH Factor (OsPIF14), as binding to the OsDREB1B promoter. bHLH proteins are able to bind to hexameric E-box (CANNTG) or N-box (CACG(A/C)G) motifs, depending on transcriptional activity. We have shown that OsPIF14 binds to the OsDREB1B promoter through two N-boxes and that the flanking regions of the hexameric core are essential for protein-DNA interaction and stability. We also showed that OsPIF14 down-regulates OsDREB1B gene expression in rice protoplasts, corroborating the OsPIF14 repressor activity observed in the transactivation assays using Arabidopsis protoplasts. In addition, we showed that OsPIF14 is indeed a phytochrome interacting factor, which preferentially binds to the active form (Pfr) of rice phytochrome B. This raises the possibility that OsPIF14 activity might be modulated by light. However, we did not observe any regulation of the OsDREB1B gene expression by light under control conditions. Moreover, OsPIF14 gene expression was shown to be modulated by different treatments, such as drought, salt, cold and ABA. Interestingly, OsPIF14 showed also a specific cold-induced alternative splicing. All together, these results suggest the possibility that OsPIF14 is involved in cross-talk between light and stress signaling through interaction with the OsDREB1B promoter. Although in the absence of stress, OsDREB1B gene expression was not regulated by light, given previous reports, it remains possible that OsPIF14 has a role in light modulation of stress responses.

  5. Rice phytochrome-interacting factor protein OsPIF14 represses OsDREB1B gene expression through an extended N-box and interacts preferentially with the active form of phytochrome B

    SciTech Connect

    Cordeiro, André M.; Figueiredo, Duarte D.; Tepperman, James; Borba, Ana Rita; Lourenço, Tiago; Abreu, Isabel A.; Ouwerkerk, Pieter B. F.; Quail, Peter H.; Margarida Oliveira, M.; Saibo, Nelson J. M.

    2015-12-28

    DREB1/CBF genes, known as major regulators of plant stress responses, are rapidly and transiently induced by low temperatures. Using a yeast one-hybrid screening, we identified a putative Phytochrome-Interacting bHLH Factor (OsPIF14), as binding to the OsDREB1B promoter. bHLH proteins are able to bind to hexameric E-box (CANNTG) or N-box (CACG(A/C)G) motifs, depending on transcriptional activity. We have shown that OsPIF14 binds to the OsDREB1B promoter through two N-boxes and that the flanking regions of the hexameric core are essential for protein–DNA interaction and stability. We also showed that OsPIF14 down-regulates OsDREB1B gene expression in rice protoplasts, corroborating the OsPIF14 repressor activity observed in the transactivation assays using Arabidopsis protoplasts. Additionally, we showed that OsPIF14 is indeed a phytochrome interacting factor, which preferentially binds to the active form (Pfr) of rice phytochrome B. This raises the possibility that OsPIF14 activity might be modulated by light. However, we did not observe any regulation of the OsDREB1B gene expression by light under control conditions. Moreover, OsPIF14 gene expression was shown to be modulated by different treatments, such as drought, salt, cold and ABA. Interestingly, OsPIF14 showed also a specific cold-induced alternative splicing. Our results suggest the possibility that OsPIF14 is involved in cross-talk between light and stress signaling through interaction with the OsDREB1B promoter. Finally, although in the absence of stress, OsDREB1B gene expression was not regulated by light, given previous reports, it remains possible that OsPIF14 has a role in light modulation of stress responses.

  6. Physical nature of interactions in Zn(II) complexes with 2,2'-bipyridyl: quantum theory of atoms in molecules (QTAIM), interacting quantum atoms (IQA), noncovalent interactions (NCI), and extended transition state coupled with natural orbitals for chemical valence (ETS-NOCV) comparative studies.

    PubMed

    Cukrowski, Ignacy; de Lange, Jurgens H; Mitoraj, Mariusz

    2014-01-23

    In the present account factors determining the stability of ZnL, ZnL2, and ZnL3 complexes (L = bpy, 2,2′-bipyridyl) were characterized on the basis of various techniques: the quantum theory of atoms in molecules (QTAIM), energy decomposition schemes based on interacting quantum atoms (IQA), and extended transition state coupled with natural orbitals for chemical valence (ETS-NOCV). Finally, the noncovalent interactions (NCI) index was also applied. All methods consistently indicated that the strength of the coordination bonds, Zn–O and Zn–N, decreases from ZnL to ZnL3. Importantly, it has been identified that the strength of secondary intramolecular heteropolar hydrogen bonding interactions, CH···O and CH···N, increases when going from ZnL to ZnL3. A similar trend appeared to be valid for the π-bonding as well as electrostatic stabilization. In addition to the above leading bonding contributions, all techniques suggested the existence of very subtle, but non-negligible additional stabilization from the CH···HC electronic exchange channel; these interactions are the weakest among all considered here. From IQA it was found that the local diatomic interaction energy, Eint(H,H), amounts at HF to −2.5, −2.7, and −2.9 kcal mol(–1) for ZnL, ZnL2, and ZnL3, respectively (−2.1 kcal mol(–1) for ZnL at MP2). NOCV-based deformation density channels showed that formation of CH--HC contacts in Zn complexes causes significant polarization of σ(C–H) bonds, which accordingly leads to charge accumulation in the CH···HC bay region. Charge depletion from σ(C–H) bonds was also reflected in the calculated spin–spin (1)J(C–H) coupling constants, which decrease from 177.06 Hz (ZnL) to 173.87 Hz (ZnL3). This last result supports our findings of an increase in the local electronic CH···HC stabilization from ZnL to ZnL3 found from QTAIM, IQA, and ETS-NOCV. Finally, this work unites for the first time the results from four methods that are widely

  7. Review of the Thermodynamic Properties of Mg(NO3)2(ap), and Their Representation with the Standard and Extended Ion-Interaction (Pitzer) Models at 298.15 K

    SciTech Connect

    Rard, J A; Wijesinghe, A M; Wolery, T J

    2004-03-30

    Published thermodynamic data yielding the osmotic coefficients, relative apparent molar enthalpies, and apparent molar heat capacities of Mg(NO{sub 3}){sub 2}(aq) have been collected, recalculated consistently, and critically assessed. The more reliable of these data have been used to evaluate the parameters of the standard three-parameter form of Pitzer's ion-interaction model to higher molalities than previously available, along with the parameters of Archer's four-parameter, extended ion-interaction model, at 298.15 K. Published experimental thermodynamic data were essentially represented equally well by these two models, provided that the exponential coefficient {alpha}{sub 1} of the standard Pitzer model is fixed at the optimum value of {alpha}{sub 1} = 1.55 kg{sup -1/2} x mol{sup -1/2} rather than the traditional value of {alpha}{sub 1} = 2.0 kg{sup -1/2} x mol{sup -1/2} The use of the standard Pitzer model with this modified {alpha}{sub 1} value is recommended for Mg(NO{sub 3}){sub 2}(aq). In addition, an empirical equation is given for the variation of the water activity of a saturated solution with temperature, from 273.54 to 328.20 K, with Mg(NO{sub 3}){sub 2}(aq) x 6H{sub 2}O(s) as the solid phase.

  8. Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives.

    PubMed

    Eldehna, Wagdy M; Abou-Seri, Sahar M; El Kerdawy, Ahmed M; Ayyad, Rezk R; Hamdy, Abdallah M; Ghabbour, Hazem A; Ali, Mamdouh M; Abou El Ella, Dalal A

    2016-05-04

    A series of anilinophthalazine derivatives 4a-j was initially synthesized and tested for its VEGFR-2 inhibitory activity where it showed promising activity (IC50 = 0.636-5.76 μM). Molecular docking studies guidance was used to improve the binding affinity for series 4a-j towards VEGFR-2 active site. This improvement was achieved by increasing the hydrophobic interaction with the hydrophobic back pocket of the VEGFR-2 active site lined with the hydrophobic side chains of Ile888, Leu889, Ile892, Val898, Val899, Leu1019 and Ile1044. Increasing the hydrophobic interaction was accomplished by extending the anilinophthalazine scaffold with a substituted phenyl moiety through an uriedo linker which should give this extension the flexibility required to accommodate itself deeply into the hydrophobic back pocket. As planned, the designed uriedo-anilinophthalazines 7a-i showed superior binding affinity than their anilinophthalazine parents (IC50 = 0.083-0.473 μM). In particular, compounds 7g-i showed IC50 of 0.086, 0.083 and 0.086 μM, respectively, which are better than that of the reference drug sorafenib (IC50 = 0.09 μM).

  9. Functional Extended Redundancy Analysis

    ERIC Educational Resources Information Center

    Hwang, Heungsun; Suk, Hye Won; Lee, Jang-Han; Moskowitz, D. S.; Lim, Jooseop

    2012-01-01

    We propose a functional version of extended redundancy analysis that examines directional relationships among several sets of multivariate variables. As in extended redundancy analysis, the proposed method posits that a weighed composite of each set of exogenous variables influences a set of endogenous variables. It further considers endogenous…

  10. Extended family medicine training

    PubMed Central

    Slade, Steve; Ross, Shelley; Lawrence, Kathrine; Archibald, Douglas; Mackay, Maria Palacios; Oandasan, Ivy F.

    2016-01-01

    Abstract Objective To examine trends in family medicine training at a time when substantial pedagogic change is under way, focusing on factors that relate to extended family medicine training. Design Aggregate-level secondary data analysis based on the Canadian Post-MD Education Registry. Setting Canada. Participants All Canadian citizens and permanent residents who were registered in postgraduate family medicine training programs within Canadian faculties of medicine from 1995 to 2013. Main outcome measures Number and proportion of family medicine residents exiting 2-year and extended (third-year and above) family medicine training programs, as well as the types and numbers of extended training programs offered in 2015. Results The proportion of family medicine trainees pursuing extended training almost doubled during the study period, going from 10.9% in 1995 to 21.1% in 2013. Men and Canadian medical graduates were more likely to take extended family medicine training. Among the 5 most recent family medicine exit cohorts (from 2009 to 2013), 25.9% of men completed extended training programs compared with 18.3% of women, and 23.1% of Canadian medical graduates completed extended training compared with 13.6% of international medical graduates. Family medicine programs vary substantially with respect to the proportion of their trainees who undertake extended training, ranging from a low of 12.3% to a high of 35.1% among trainees exiting from 2011 to 2013. Conclusion New initiatives, such as the Triple C Competency-based Curriculum, CanMEDS–Family Medicine, and Certificates of Added Competence, have emerged as part of family medicine education and credentialing. In acknowledgment of the potential effect of these initiatives, it is important that future research examine how pedagogic change and, in particular, extended training shapes the care family physicians offer their patients. As part of that research it will be important to measure the breadth and uptake of

  11. Crystal structure of the extended-spectrum β-lactamase PER-2 and insights into the role of specific residues in the interaction with β-lactams and β-lactamase inhibitors.

    PubMed

    Ruggiero, Melina; Kerff, Frédéric; Herman, Raphaël; Sapunaric, Frédéric; Galleni, Moreno; Gutkind, Gabriel; Charlier, Paulette; Sauvage, Eric; Power, Pablo

    2014-10-01

    PER-2 belongs to a small (7 members to date) group of extended-spectrum β-lactamases. It has 88% amino acid identity with PER-1 and both display high catalytic efficiencies toward most β-lactams. In this study, we determined the X-ray structure of PER-2 at 2.20 Å and evaluated the possible role of several residues in the structure and activity toward β-lactams and mechanism-based inhibitors. PER-2 is defined by the presence of a singular trans bond between residues 166 to 167, which generates an inverted Ω loop, an expanded fold of this domain that results in a wide active site cavity that allows for efficient hydrolysis of antibiotics like the oxyimino-cephalosporins, and a series of exclusive interactions between residues not frequently involved in the stabilization of the active site in other class A β-lactamases. PER β-lactamases might be included within a cluster of evolutionarily related enzymes harboring the conserved residues Asp136 and Asn179. Other signature residues that define these enzymes seem to be Gln69, Arg220, Thr237, and probably Arg/Lys240A ("A" indicates an insertion according to Ambler's scheme for residue numbering in PER β-lactamases), with structurally important roles in the stabilization of the active site and proper orientation of catalytic water molecules, among others. We propose, supported by simulated models of PER-2 in combination with different β-lactams, the presence of a hydrogen-bond network connecting Ser70-Gln69-water-Thr237-Arg220 that might be important for the proper activity and inhibition of the enzyme. Therefore, we expect that mutations occurring in these positions will have impacts on the overall hydrolytic behavior.

  12. Crystal Structure of the Extended-Spectrum β-Lactamase PER-2 and Insights into the Role of Specific Residues in the Interaction with β-Lactams and β-Lactamase Inhibitors

    PubMed Central

    Ruggiero, Melina; Kerff, Frédéric; Herman, Raphaël; Sapunaric, Frédéric; Galleni, Moreno; Gutkind, Gabriel; Charlier, Paulette; Sauvage, Eric

    2014-01-01

    PER-2 belongs to a small (7 members to date) group of extended-spectrum β-lactamases. It has 88% amino acid identity with PER-1 and both display high catalytic efficiencies toward most β-lactams. In this study, we determined the X-ray structure of PER-2 at 2.20 Å and evaluated the possible role of several residues in the structure and activity toward β-lactams and mechanism-based inhibitors. PER-2 is defined by the presence of a singular trans bond between residues 166 to 167, which generates an inverted Ω loop, an expanded fold of this domain that results in a wide active site cavity that allows for efficient hydrolysis of antibiotics like the oxyimino-cephalosporins, and a series of exclusive interactions between residues not frequently involved in the stabilization of the active site in other class A β-lactamases. PER β-lactamases might be included within a cluster of evolutionarily related enzymes harboring the conserved residues Asp136 and Asn179. Other signature residues that define these enzymes seem to be Gln69, Arg220, Thr237, and probably Arg/Lys240A (“A” indicates an insertion according to Ambler's scheme for residue numbering in PER β-lactamases), with structurally important roles in the stabilization of the active site and proper orientation of catalytic water molecules, among others. We propose, supported by simulated models of PER-2 in combination with different β-lactams, the presence of a hydrogen-bond network connecting Ser70-Gln69-water-Thr237-Arg220 that might be important for the proper activity and inhibition of the enzyme. Therefore, we expect that mutations occurring in these positions will have impacts on the overall hydrolytic behavior. PMID:25070104

  13. Isopiestic Determination of the Osmotic and Activity Coefficients of Li2SO4(aq) at T = 298.15 and 323.15 K, and Representation with an Extended Ion-interaction (Pitzer) model

    SciTech Connect

    Rard, J A; Clegg, S L; Palmer, D A

    2007-01-03

    Isopiestic vapor-pressure measurements were made for Li{sub 2}SO{sub 4}(aq) from 0.1069 to 2.8190 mol {center_dot} kg{sup -1} at 298.15 K, and from 0.1148 to 2.7969 mol {center_dot} kg{sup -1} at 323.15 K, with NaCl(aq) as the reference standard. Published thermodynamic data for this system were reviewed, recalculated for consistency, and critically assessed. The present results and the more reliable published results were used to evaluate the parameters of an extended version of Pitzer's ion-interaction model with an ionic-strength dependent third virial coefficient, as well as those of the standard Pitzer model, for the osmotic and activity coefficients at both temperatures. Published enthalpies of dilution at 298.15 K were also analyzed to yield the parameters of the ion-interaction models for the relative apparent molar enthalpies of dilution. The resulting models at 298.15 K are valid to the saturated solution molality of the thermodynamically stable phase Li{sub 2}SO{sub 4} {center_dot} H{sub 2}O(cr). Solubilities of Li{sub 2}SO{sub 4} {center_dot} H{sub 2}O(cr) at 298.15 K were assessed, and the selected value of m(sat.) = 3.13 {+-} 0.04 mol {center_dot} kg{sup -1} was used to evaluate the thermodynamic solubility product K{sub s}(Li{sub 2}SO{sub 4} {center_dot} H{sub 2}O, cr, 298.15 K) = (2.62 {+-} 0.19) and a CODATA-compatible standard molar Gibbs energy of formation {Delta}{sub f}G{sub m}{sup o} (Li{sub 2}SO{sub 4} {center_dot} H{sub 2}O, cr, 298.15 K) = -(1564.6 {+-} 0.5) kJ {center_dot} mol{sup -1}.

  14. Extended spider cognition.

    PubMed

    Japyassú, Hilton F; Laland, Kevin N

    2017-02-07

    There is a tension between the conception of cognition as a central nervous system (CNS) process and a view of cognition as extending towards the body or the contiguous environment. The centralised conception requires large or complex nervous systems to cope with complex environments. Conversely, the extended conception involves the outsourcing of information processing to the body or environment, thus making fewer demands on the processing power of the CNS. The evolution of extended cognition should be particularly favoured among small, generalist predators such as spiders, and here, we review the literature to evaluate the fit of empirical data with these contrasting models of cognition. Spiders do not seem to be cognitively limited, displaying a large diversity of learning processes, from habituation to contextual learning, including a sense of numerosity. To tease apart the central from the extended cognition, we apply the mutual manipulability criterion, testing the existence of reciprocal causal links between the putative elements of the system. We conclude that the web threads and configurations are integral parts of the cognitive systems. The extension of cognition to the web helps to explain some puzzling features of spider behaviour and seems to promote evolvability within the group, enhancing innovation through cognitive connectivity to variable habitat features. Graded changes in relative brain size could also be explained by outsourcing information processing to environmental features. More generally, niche-constructed structures emerge as prime candidates for extending animal cognition, generating the selective pressures that help to shape the evolving cognitive system.

  15. Extending quantum mechanics entails extending special relativity

    NASA Astrophysics Data System (ADS)

    Aravinda, S.; Srikanth, R.

    2016-05-01

    The complementarity between signaling and randomness in any communicated resource that can simulate singlet statistics is generalized by relaxing the assumption of free will in the choice of measurement settings. We show how to construct an ontological extension for quantum mechanics (QMs) through the oblivious embedding of a sound simulation protocol in a Newtonian spacetime. Minkowski or other intermediate spacetimes are ruled out as the locus of the embedding by virtue of hidden influence inequalities. The complementarity transferred from a simulation to the extension unifies a number of results about quantum non-locality, and implies that special relativity has a different significance for the ontological model and for the operational theory it reproduces. Only the latter, being experimentally accessible, is required to be Lorentz covariant. There may be certain Lorentz non-covariant elements at the ontological level, but they will be inaccessible at the operational level in a valid extension. Certain arguments against the extendability of QM, due to Conway and Kochen (2009) and Colbeck and Renner (2012), are attributed to their assumption that the spacetime at the ontological level has Minkowski causal structure.

  16. Extendable pipe crawler

    DOEpatents

    Hapstack, M.

    1991-05-28

    A pipe crawler is described having a front leg assembly and a back leg assembly connected together by two air cylinders, each leg assembly having four extendable legs and a pair of actuators for sliding the extendable legs radially outward to increase the range of the legs when the pipe crawler enters a section of a pipe having a larger diameter. The crawler crawls by inchworm'-like motion, the front leg assembly and back leg assembly alternately engaging and disengaging the wall of the pipe to hold the pipe crawler as the air cylinders alternately advance the front leg assembly and bring up the rear leg assembly. The pair of actuators of each leg assembly are parallel, adjacent and opposing acting so that each slides two adjacent extendable legs radially outward. 5 figures.

  17. Modified Iterative Extended Hueckel. 1: Theory

    NASA Technical Reports Server (NTRS)

    Aronowitz, S.

    1980-01-01

    Iterative Extended Huekel is modified by inclusion of explicit effective internuclear and electronic interactions. The one electron energies are shown to obey a variational principle because of the form of the effective electronic interactions. The modifications permit mimicking of aspects of valence bond theory with the additional feature that the energies associated with valence bond type structures are explicitly calculated. In turn, a hybrid molecular, orbital valence, bond scheme is introduced which incorporates variant total molecular electronic density distributions similar to the way that Iterative Extended Hueckel incorporates atoms.

  18. Towards Extended Vantage Theory

    ERIC Educational Resources Information Center

    Glaz, Adam

    2010-01-01

    The applicability of Vantage Theory (VT), a model of (colour) categorization, to linguistic data largely depends on the modifications and adaptations of the model for the purpose. An attempt to do so proposed here, called Extended Vantage Theory (EVT), slightly reformulates the VT conception of vantage by capitalizing on some of the entailments of…

  19. Propelling Extended Objects

    ERIC Educational Resources Information Center

    Humbert, Richard

    2010-01-01

    A force acting on just part of an extended object (either a solid or a volume of a liquid) can cause all of it to move. That motion is due to the transmission of the force through the object by its material. This paper discusses how the force is distributed to all of the object by a gradient of stress or pressure in it, which creates the local…

  20. extendFromReads

    SciTech Connect

    Williams, Kelly P.

    2013-10-03

    This package assists in genome assembly. extendFromReads takes as input a set of Illumina (eg, MiSeq) DNA sequencing reads, a query seed sequence and a direction to extend the seed. The algorithm collects all seed--]matching reads (flipping reverse--]orientation hits), trims off the seed and additional sequence in the other direction, sorts the remaining sequences alphabetically, and prints them aligned without gaps from the point of seed trimming. This produces a visual display distinguishing the flanks of multi-]copy seeds. A companion script hitMates.pl collects the mates of seed--]hi]ng reads, whose alignment reveals longer extensions from the seed. The collect/trim/sort strategy was made iterative and scaled up in the script denovo.pl, for de novo contig assembly. An index is pre--]built using indexReads.pl that for each unique 21--]mer found in all the reads, records its gfateh of extension (whether extendable, blocked by low coverage, or blocked by branching after a duplicated sequence) and other characteristics. Importantly, denovo.pl records all branchings that follow a branching contig endpoint, providing contig-]extension information

  1. Dicyanometallates as Model Extended Frameworks

    PubMed Central

    2016-01-01

    We report the structures of eight new dicyanometallate frameworks containing molecular extra-framework cations. These systems include a number of hybrid inorganic–organic analogues of conventional ceramics, such as Ruddlesden–Popper phases and perovskites. The structure types adopted are rationalized in the broader context of all known dicyanometallate framework structures. We show that the structural diversity of this family can be understood in terms of (i) the charge and coordination preferences of the particular metal cation acting as framework node, and (ii) the size, shape, and extent of incorporation of extra-framework cations. In this way, we suggest that dicyanometallates form a particularly attractive model family of extended frameworks in which to explore the interplay between molecular degrees of freedom, framework topology, and supramolecular interactions. PMID:27057759

  2. Time-Extended Multiple Group Counseling.

    ERIC Educational Resources Information Center

    Ficek, Daniel E.

    Time-extended groups provide the following: (1) they ease the need to get things started immediately, (2) they provide the opportunity for interaction to be carried to its natural end-point, (3) they allow a greater range of techniques to be experienced by members, (4) they increase the chances for therapeutic contact, (5) they allow participants…

  3. Inequalities of extended beta and extended hypergeometric functions.

    PubMed

    Mondal, Saiful R

    2017-01-01

    We study the log-convexity of the extended beta functions. As a consequence, we establish Turán-type inequalities. The monotonicity, log-convexity, log-concavity of extended hypergeometric functions are deduced by using the inequalities on extended beta functions. The particular cases of those results also give the Turán-type inequalities for extended confluent and extended Gaussian hypergeometric functions. Some reverses of Turán-type inequalities are also derived.

  4. Extended cooperative control synthesis

    NASA Technical Reports Server (NTRS)

    Davidson, John B.; Schmidt, David K.

    1994-01-01

    This paper reports on research for extending the Cooperative Control Synthesis methodology to include a more accurate modeling of the pilot's controller dynamics. Cooperative Control Synthesis (CCS) is a methodology that addresses the problem of how to design control laws for piloted, high-order, multivariate systems and/or non-conventional dynamic configurations in the absence of flying qualities specifications. This is accomplished by emphasizing the parallel structure inherent in any pilot-controlled, augmented vehicle. The original CCS methodology is extended to include the Modified Optimal Control Model (MOCM), which is based upon the optimal control model of the human operator developed by Kleinman, Baron, and Levison in 1970. This model provides a modeling of the pilot's compensation dynamics that is more accurate than the simplified pilot dynamic representation currently in the CCS methodology. Inclusion of the MOCM into the CCS also enables the modeling of pilot-observation perception thresholds and pilot-observation attention allocation affects. This Extended Cooperative Control Synthesis (ECCS) allows for the direct calculation of pilot and system open- and closed-loop transfer functions in pole/zero form and is readily implemented in current software capable of analysis and design for dynamic systems. Example results based upon synthesizing an augmentation control law for an acceleration command system in a compensatory tracking task using the ECCS are compared with a similar synthesis performed by using the original CCS methodology. The ECCS is shown to provide augmentation control laws that yield more favorable, predicted closed-loop flying qualities and tracking performance than those synthesized using the original CCS methodology.

  5. Extended Wordsearches in Chemistry

    NASA Astrophysics Data System (ADS)

    Cotton, Simon

    1998-04-01

    Students can be encouraged to develop their factual knowledge by use of puzzles. One strategy described here is the extended wordsearch, where the wordsearch element generates a number of words or phrases from which the answers to a series of questions are selected. The wordsearch can be generated with the aid of computer programs, though in order to make them suitable for students with dyslexia or other learning difficulties, a simpler form is more appropriate. These problems can be employed in a variety of contexts, for example, as topic tests and classroom end-of-lesson fillers. An example is provided in the area of calcium chemistry. Sources of suitable software are listed.

  6. ALMA Extended Array

    NASA Astrophysics Data System (ADS)

    Kameno, S.; Nakai, N.; Honma, M.

    2013-10-01

    We propose to append five 12-m antennas within 300-km from ALMA to realize high angular resolution of < 1 mas and sensitivity to detect Tb < 1000 K. This ALMA extended array offers a new parameter space of "Thermal universe with VLBI resolution". Proposed science case includes black-hole formation in sub-mm galaxies, mass accretion processes onto protostars, imaging stellar photospheres, distance measurements of stars, and so on. The array also functions as a part of sub-mm VLBI that targets black-hole imaging.

  7. Symbolic computation of the Hartree-Fock energy from a chiral EFT three-nucleon interaction at N 2LO

    NASA Astrophysics Data System (ADS)

    Gebremariam, B.; Bogner, S. K.; Duguet, T.

    2010-06-01

    We present the first of a two-part Mathematica notebook collection that implements a symbolic approach for the application of the density matrix expansion (DME) to the Hartree-Fock (HF) energy from a chiral effective field theory (EFT) three-nucleon interaction at N 2LO. The final output from the notebooks is a Skyrme-like energy density functional that provides a quasi-local approximation to the non-local HF energy. In this paper, we discuss the derivation of the HF energy and its simplification in terms of the scalar/vector-isoscalar/isovector parts of the one-body density matrix. Furthermore, a set of steps is described and illustrated on how to extend the approach to other three-nucleon interactions. Program summaryProgram title: SymbHFNNN Catalogue identifier: AEGC_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEGC_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 96 666 No. of bytes in distributed program, including test data, etc.: 378 083 Distribution format: tar.gz Programming language: Mathematica 7.1 Computer: Any computer running Mathematica 6.0 and later versions Operating system: Windows Xp, Linux/Unix RAM: 256 Mb Classification: 5, 17.16, 17.22 Nature of problem: The calculation of the HF energy from the chiral EFT three-nucleon interaction at N 2LO involves tremendous spin-isospin algebra. The problem is compounded by the need to eventually obtain a quasi-local approximation to the HF energy, which requires the HF energy to be expressed in terms of scalar/vector-isoscalar/isovector parts of the one-body density matrix. The Mathematica notebooks discussed in this paper solve the latter issue. Solution method: The HF energy from the chiral EFT three-nucleon interaction at N 2LO is cast into a form suitable for an automatic simplification of

  8. Pair extended coupled cluster doubles

    SciTech Connect

    Henderson, Thomas M.; Scuseria, Gustavo E.; Bulik, Ireneusz W.

    2015-06-07

    The accurate and efficient description of strongly correlated systems remains an important challenge for computational methods. Doubly occupied configuration interaction (DOCI), in which all electrons are paired and no correlations which break these pairs are permitted, can in many cases provide an accurate account of strong correlations, albeit at combinatorial computational cost. Recently, there has been significant interest in a method we refer to as pair coupled cluster doubles (pCCD), a variant of coupled cluster doubles in which the electrons are paired. This is simply because pCCD provides energies nearly identical to those of DOCI, but at mean-field computational cost (disregarding the cost of the two-electron integral transformation). Here, we introduce the more complete pair extended coupled cluster doubles (pECCD) approach which, like pCCD, has mean-field cost and reproduces DOCI energetically. We show that unlike pCCD, pECCD also reproduces the DOCI wave function with high accuracy. Moreover, pECCD yields sensible albeit inexact results even for attractive interactions where pCCD breaks down.

  9. Extending juvenility in grasses

    DOEpatents

    Kaeppler, Shawn; de Leon Gatti, Natalia; Foerster, Jillian

    2017-04-11

    The present invention relates to compositions and methods for modulating the juvenile to adult developmental growth transition in plants, such as grasses (e.g. maize). In particular, the invention provides methods for enhancing agronomic properties in plants by modulating expression of GRMZM2G362718, GRMZM2G096016, or homologs thereof. Modulation of expression of one or more additional genes which affect juvenile to adult developmental growth transition such as Glossy15 or Cg1, in conjunction with such modulation of expression is also contemplated. Nucleic acid constructs for down-regulation of GRMZM2G362718 and/or GRMZM2G096016 are also contemplated, as are transgenic plants and products produced there from, that demonstrate altered, such as extended juvenile growth, and display associated phenotypes such as enhanced yield, improved digestibility, and increased disease resistance. Plants described herein may be used, for example, as improved forage or feed crops or in biofuel production.

  10. Stars with Extended Atmospheres

    NASA Astrophysics Data System (ADS)

    Sterken, C.

    2002-12-01

    This Workshop consisted of a full-day meeting of the Working Group "Sterren met Uitgebreide Atmosferen" (SUA, Working Group Stars with Extended Atmospheres), a discussion group founded in 1979 by Kees de Jager, Karel van der Hucht and Pik Sin The. This loose association of astronomers and astronomy students working in the Dutch-speaking part of the Low Countries (The Netherlands and Flanders) organised at regular intervals one-day meetings at the Universities of Utrecht, Leiden, Amsterdam and Brussels. These meetings consisted of the presentation of scientific results by junior as well as senior members of the group, and by discussions between the participants. As such, the SUA meetings became a forum for the exchange of ideas, and for asking questions and advice in an informal atmosphere. Kees de Jager has been chairman of the WG SUA from the beginning in 1979 till today, as the leading source of inspiration. At the occasion of Prof. Kees de Jager's 80th birthday, we decided to collect the presented talks in written form as a Festschrift in honour of this well-respected and much beloved scientist, teacher and friend. The first three papers deal with the personality of Kees de Jager, more specifically with his role as a supervisor and mentor of young researchers and as a catalyst in the research work of his colleagues. And also about his remarkable role in the establishment of astronomy education and research at the University of Brussels. The next presentation is a very detailed review of solar research, a field in which Cees was prominently active for many years. Then follow several papers dealing with stars about which Kees is a true expert: massive stars and extended atmospheres.

  11. Odd-even staggering in the neutron-proton interaction and nuclear mass models

    NASA Astrophysics Data System (ADS)

    Cheng, Y. Y.; Zhao, Y. M.; Arima, A.

    2015-02-01

    In this paper we study odd-even staggering of the empirical neutron-proton interaction between the last neutron and the last proton, denoted as δ V1 n -1 p , and its consequence in the Garvey-Kelson mass relations (GKs) and nuclear mass models. The root-mean-squared deviations of predicted masses respectively for even-A and odd-A nuclei by using two combinatorial GKs suggest a large odd-even staggering of δ V1 n -1 p between even-odd and odd-even nuclei, while the odd-even difference of δ V1 n -1 p between even-even and odd-odd nuclei is much smaller. The contribution of the odd-even staggering of δ V1 n -1 p between even-A and odd-A nuclei in deviations of theoretical δ V1 n -1 p values of the Duflo-Zuker model and the improved Weizs a ̈cker -Skyrme model are well represented by an isospin-dependent term. The consideration of this odd-even staggering improves our description of binding energies and one-neutron separation energies in both the Duflo-Zuker model and the improved Weizs a ̈cker -Skyrme model.

  12. Finite-Range Separable Pairing Interaction Within New N3LO DFT Approach

    NASA Astrophysics Data System (ADS)

    Veselý, P.; Dobaczewski, J.; Michel, N.; Toivanen, J.

    2011-10-01

    For over four decades, the Skyrme functional within various parametrizations has been used to calculate nuclear properties. In the last few years there was a number of attempts to improve its performance and introduce generalized forms. In particular, the most general phenomenologi-cal quasi-local energy density functional, which contains all combinations of density, spin-density, and their derivatives up to the sixth order (N3LO), was proposed in reference [1]. Since in the phe-nomenological functional approaches the particle-particle (pp) interaction channel is treated independently from the particle-hole (ph) channel, there remains a question of what pairing interaction is suitable to use within the N3LO energy functional. In our study, we use the separable, finite-range, translationally invariant form given in [2], which we generalize to the arbitrary angular momentum channel. We discuss the application of this pairing interaction within the N3LO energy functional.

  13. Giotto Extended Mission (GEM)

    NASA Technical Reports Server (NTRS)

    Wilkins, D. E. B.; Grensemann, M.

    1991-01-01

    The primary objectives of the Giotto Extended Mission (GEM), are to determine the composition and physical state of the Grigg Skjellerup Comet's nucleus; to determine the processes that govern the composition and distribution of neutral and ionized species in the cometary atmosphere. Giotto consists of a single European Space Agency (ESA) spacecraft that was launched in 1985 from Center Spatial Guyanis in French Guiana on an Ariane launch vehicle. After a successful launch into geostationary orbit and a heliocentric transfer trajectory, the spacecraft successfully encountered Halley's Comet in 1986. One month after encountering Halley's Comet, Mar. 1986, the spacecraft was placed in hibernation in a heliocentric orbit slightly less than 1 AU. Between Feb. and Jul. 1990 the spacecraft was successfully reactivated, checked out, and placed on a trajectory course to intercept comet Grigg Skjellerup. The spacecraft has been in hibernation since Jul. 1990. Information is presented in tabular form in the following areas: coverage goals, Deep Space Network Support, frequency assignments, telemetry, command, and tracking support responsibility.

  14. An Extended Lagrangian Method

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing

    1995-01-01

    A unique formulation of describing fluid motion is presented. The method, referred to as 'extended Lagrangian method,' is interesting from both theoretical and numerical points of view. The formulation offers accuracy in numerical solution by avoiding numerical diffusion resulting from mixing of fluxes in the Eulerian description. The present method and the Arbitrary Lagrangian-Eulerian (ALE) method have a similarity in spirit-eliminating the cross-streamline numerical diffusion. For this purpose, we suggest a simple grid constraint condition and utilize an accurate discretization procedure. This grid constraint is only applied to the transverse cell face parallel to the local stream velocity, and hence our method for the steady state problems naturally reduces to the streamline-curvature method, without explicitly solving the steady stream-coordinate equations formulated a priori. Unlike the Lagrangian method proposed by Loh and Hui which is valid only for steady supersonic flows, the present method is general and capable of treating subsonic flows and supersonic flows as well as unsteady flows, simply by invoking in the same code an appropriate grid constraint suggested in this paper. The approach is found to be robust and stable. It automatically adapts to flow features without resorting to clustering, thereby maintaining rather uniform grid spacing throughout and large time step. Moreover, the method is shown to resolve multi-dimensional discontinuities with a high level of accuracy, similar to that found in one-dimensional problems.

  15. Extended chameleon models

    NASA Astrophysics Data System (ADS)

    Brax, Philippe; Tamanini, Nicola

    2016-05-01

    We extend the chameleon models by considering scalar-fluid theories where the coupling between matter and the scalar field can be represented by a quadratic effective potential with density-dependent minimum and mass. In this context, we study the effects of the scalar field on Solar System tests of gravity and show that models passing these stringent constraints can still induce large modifications of Newton's law on galactic scales. On these scales we analyze models which could lead to a percent deviation of Newton's law outside the virial radius. We then model the dark matter halo as a Navarro-Frenk-White profile and explicitly find that the fifth force can give large contributions around the galactic core in a particular model where the scalar field mass is constant and the minimum of its potential varies linearly with the matter density. At cosmological distances, we find that this model does not alter the growth of large scale structures and therefore would be best tested on galactic scales, where interesting signatures might arise in the galaxy rotation curves.

  16. Extended Analysis of Mo VI

    NASA Astrophysics Data System (ADS)

    Edlén, B.; Rahimullah, K.; Tauheed, A.; Chaghtai, M. S. Z.

    1985-09-01

    The analysis of the RbI-like spectrum Mo VI has been extended to include a total of some 110 classified lines and 44 energy levels belonging to the one-electron configurations 4s24p6(1S) nl with n ranging up to 9 and l up to 7. The analysis is based on recordings of vacuum spark spectra made at Lund in the region 230-2350 Å, complemented by a list of lines from 2193 to 6336 Å observed and identified by Romanov and Striganov in a Penning type arc discharge. The one-electron level system is partly mixed with core-excited configurations, not treated in the present paper. Especially the nf series is strongly perturbed by 4s24p54d2, and an anomalous behaviour of the ng series is explained by interaction with the 2G term of 4s4p64d2. The ionization limit, derived from 6h, 7i and 8k by means of the polarization formula, is found to be 555 132 ± 2 cm-1.

  17. Postpartum Early and Extended Contact: Quality, Quantity or Both?

    ERIC Educational Resources Information Center

    Hopkins, John B.; Vietze, Peter M.

    This study examined the effects of early vs. extended mother-infant contact on infant, maternal and interactional outcomes in the lying-in period for 104 lower class mother-infant dyads. The early contact treatment consisted of placing the mother and neonate together for 10 to 45 minutes within the first 3 postpartum hours. The extended contact…

  18. Solute drag on perfect and extended dislocations

    NASA Astrophysics Data System (ADS)

    Sills, R. B.; Cai, W.

    2016-04-01

    The drag force exerted on a moving dislocation by a field of mobile solutes is studied in the steady state. The drag force is numerically calculated as a function of the dislocation velocity for both perfect and extended dislocations. The sensitivity of the non-dimensionalized force-velocity curve to the various controlling parameters is assessed, and an approximate analytical force-velocity expression is given. A non-dimensional parameter S characterizing the strength of the solute-dislocation interaction, the background solute fraction ?, and the dislocation character angle ?, are found to have the strongest influence on the force-velocity curve. Within the model considered here, a perfect screw dislocation experiences no solute drag, but an extended screw dislocation experiences a non-zero drag force that is about 10 to 30% of the drag on an extended edge dislocation. The solutes can change the spacing between the Shockley partials in both stationary and moving extended dislocations, even when the stacking fault energy remains unaltered. Under certain conditions, the solutes destabilize an extended dislocation by either collapsing it into a perfect dislocation or causing the partials to separate unboundedly. It is proposed that the latter instability may lead to the formation of large faulted areas and deformation twins in low stacking fault energy materials containing solutes, consistent with experimental observations of copper and stainless steel containing hydrogen.

  19. NAIF Toolkit - Extended

    NASA Technical Reports Server (NTRS)

    Acton, Charles H., Jr.; Bachman, Nathaniel J.; Semenov, Boris V.; Wright, Edward D.

    2010-01-01

    The Navigation Ancillary Infor ma tion Facility (NAIF) at JPL, acting under the direction of NASA s Office of Space Science, has built a data system named SPICE (Spacecraft Planet Instrument Cmatrix Events) to assist scientists in planning and interpreting scientific observations (see figure). SPICE provides geometric and some other ancillary information needed to recover the full value of science instrument data, including correlation of individual instrument data sets with data from other instruments on the same or other spacecraft. This data system is used to produce space mission observation geometry data sets known as SPICE kernels. It is also used to read SPICE kernels and to compute derived quantities such as positions, orientations, lighting angles, etc. The SPICE toolkit consists of a subroutine/ function library, executable programs (both large applications and simple utilities that focus on kernel management), and simple examples of using SPICE toolkit subroutines. This software is very accurate, thoroughly tested, and portable to all computers. It is extremely stable and reusable on all missions. Since the previous version, three significant capabilities have been added: Interactive Data Language (IDL) interface, MATLAB interface, and a geometric event finder subsystem.

  20. From Self-Organized to Extended Criticality

    PubMed Central

    Lovecchio, Elisa; Allegrini, Paolo; Geneston, Elvis; West, Bruce J.; Grigolini, Paolo

    2012-01-01

    We address the issue of criticality that is attracting the attention of an increasing number of neurophysiologists. Our main purpose is to establish the specific nature of some dynamical processes that although physically different, are usually termed as “critical,” and we focus on those characterized by the cooperative interaction of many units. We notice that the term “criticality” has been adopted to denote both noise-induced phase transitions and Self-Organized Criticality (SOC) with no clear connection with the traditional phase transitions, namely the transformation of a thermodynamic system from one state of matter to another. We notice the recent attractive proposal of extended criticality advocated by Bailly and Longo, which is realized through a wide set of critical points rather than emerging as a singularity from a unique value of the control parameter. We study a set of cooperatively firing neurons and we show that for an extended set of interaction couplings the system exhibits a form of temporal complexity similar to that emerging at criticality from ordinary phase transitions. This extended criticality regime is characterized by three main properties: (i) In the ideal limiting case of infinitely large time period, temporal complexity corresponds to Mittag-Leffler complexity; (ii) For large values of the interaction coupling the periodic nature of the process becomes predominant while maintaining to some extent, in the intermediate time asymptotic region, the signature of complexity; (iii) Focusing our attention on firing neuron avalanches, we find two of the popular SOC properties, namely the power indexes 2 and 1.5 respectively for time length and for the intensity of the avalanches. We derive the main conclusion that SOC emerges from extended criticality, thereby explaining the experimental observation of Plenz and Beggs: avalanches occur in time with surprisingly regularity, in apparent conflict with the temporal complexity of physical

  1. Contribution of excited states to stellar weak-interaction rates in odd-A nuclei

    NASA Astrophysics Data System (ADS)

    Sarriguren, P.

    2016-05-01

    Weak-interaction rates, including β decay and electron capture, are studied in several odd-A nuclei in the p f -shell region at various densities and temperatures of astrophysical interest. Special attention is paid to the relative contribution to these rates of thermally populated excited states in the decaying nucleus. The nuclear structure involved in the weak processes is studied within a quasiparticle random-phase approximation with residual interactions in both particle-hole and particle-particle channels on top of a deformed Skyrme Hartree-Fock mean field with pairing correlations. In the range of densities and temperatures considered, it is found that the total rates do not differ much from the rates of the ground state fully populated. In any case, the changes are not larger than the uncertainties due to the nuclear-model dependence of the rates.

  2. Competing exotic quantum phases of spin- 12 ultracold lattice bosons with extended spin interactions

    SciTech Connect

    Chang, Chia-Chen; Rousseau, Valéry G.; Scalettar, Richard T.; Batrouni, George G.

    2015-08-12

    Advances in pure optical trapping techniques now allow the creation of degenerate Bose gases with internal degrees of freedom. Systems such as 87Rb, 39K or 23Na in the F = 1 hyperfine state offer an ideal platform for studying the interplay of super fluidity and quantum magnetism. Motivated by the experimental developments, we study ground state phases of a two-component Bose gas loaded on an optical lattice. We describe this effectively by the Bose-Hubbard Hamiltonian with onsite and near neighbor spin-spin interactions. One important feature of our investigation is the inclusion of interconversion (spin-flip) terms between the two species, which has been observed in optical lattice experiments. Furthermore, using mean-field theory and quantum Monte Carlo simulations, we map out the phase diagram of the system. A rich variety of phases is identified, including antiferromagnetic (AF) Mott insulators, ferromagnetic and AF super fluids.

  3. Extended active disturbance rejection controller

    NASA Technical Reports Server (NTRS)

    Gao, Zhiqiang (Inventor); Tian, Gang (Inventor)

    2012-01-01

    Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

  4. Extended Active Disturbance Rejection Controller

    NASA Technical Reports Server (NTRS)

    Gao, Zhiqiang (Inventor); Tian, Gang (Inventor)

    2014-01-01

    Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

  5. Extended Active Disturbance Rejection Controller

    NASA Technical Reports Server (NTRS)

    Gao, Zhiqiang (Inventor); Tian, Gang (Inventor)

    2016-01-01

    Multiple designs, systems, methods and processes for controlling a system or plant using an extended active disturbance rejection control (ADRC) based controller are presented. The extended ADRC controller accepts sensor information from the plant. The sensor information is used in conjunction with an extended state observer in combination with a predictor that estimates and predicts the current state of the plant and a co-joined estimate of the system disturbances and system dynamics. The extended state observer estimates and predictions are used in conjunction with a control law that generates an input to the system based in part on the extended state observer estimates and predictions as well as a desired trajectory for the plant to follow.

  6. Extended Relativistic Configuration Interaction and Many-body Perturbation Calculations of Spectroscopic Data for the N ≤ 6 Configurations in Ne-like Ions between Cr xv and Kr xxvii

    NASA Astrophysics Data System (ADS)

    Wang, K.; Chen, Z. B.; Si, R.; Jönsson, P.; Ekman, J.; Guo, X. L.; Li, S.; Long, F. Y.; Dang, W.; Zhao, X. H.; Hutton, R.; Chen, C. Y.; Yan, J.; Yang, X.

    2016-10-01

    Level energies, wavelengths, electric dipole, magnetic dipole, electric quadrupole, and magnetic quadrupole transition rates, oscillator strengths, and line strengths from combined relativistic configuration interaction and many-body perturbation calculations are reported for the 201 fine-structure states of the 2{s}22{p}6, 2{s}22{p}53l, 2s2{p}63l, 2{s}22{p}54l, 2s2{p}64l, 2{s}22{p}55l, and 2{s}22{p}56l configurations in all Ne-like ions between Cr xv and Kr xxvii. Calculated level energies and transition data are compared with experiments from the National Institute of Standards and Technology (NIST) and CHIANTI databases, and other recent benchmark calculations. The mean energy difference with the NIST experiments is only 0.05%. The present calculations significantly increase the amount of accurate spectroscopic data for the n > 3 states in a number of Ne-like ions of astrophysical interest. A complete data set should be helpful for analyzing new observations from solar and other astrophysical sources, and is also likely to be useful for modeling and diagnosing a variety of plasmas, including astronomical and fusion plasma.

  7. The Extended Mind: Coupling Environment and Brain

    NASA Astrophysics Data System (ADS)

    Vrobel, Susie

    2010-11-01

    This paper describes embodiment and cognitive extension as examples of strong anticipation as defined by Dubois. Clark and Chalmers formulated a thesis which states that parts of the environment, if coupled successfully, can become part of the extended mind. This coupling, be it deliberate or unintentional, shifts the observer-world boundary outwards when the observer encompasses parts of his environment. The resulting extended observer forms a new systemic whole, which consists of both the assimilated context and the recalibrated version of the original observer. Recalibration occurs when conditioning and adaptation lead to corresponding changes on the neural level, for instance, when an agent compensates for delays in a control loop. Plasticity is a prerequisite for any successful incorporation of external structures. However, uncoupled parts of the observer must remain inviolate in order to preserve the boundary. Neither the extended mind nor the core observer are absolute concepts. Depending on whether we focus on local-scale interactions or on large-scale behaviour, boundaries are formed at different interfacial cuts, which lead to either an endo- or an exo-perspective or endo- or exo-anticipation, respectively. For biological extended agents which undergo a transition from exo- to endo-states, a tell-tale sign of a successful exo-endo transition is invisibility. This invisibility occurs when the agent is no longer aware of the delay originally introduced into the control loop by the assimilated part of the environment. Explaining the world in terms of effective causality is not sufficient to account for extended minds. The latter require explanations in terms of final causation. For extended minds, this ordering principle comes in the shape of nested hierarchical layers. The interfaces of these layers may have merged for an endo-observer, whereas an exo-observer can make out the detailed structure, including artificially introduced delays. A sufficient

  8. Thermal waves in an extended hydrodynamic approach

    NASA Astrophysics Data System (ADS)

    Vasconcellos, Áurea R.; Luzzi, Roberto; Jou, David; Casas-Vazquez, José

    1994-12-01

    A study of the question of heat propagation in an extended quantum hydrodynamic approach is presented. We consider a fluid of Fermi particles in interaction with a thermal bath of bosons. The equation of evolution for the flux of energy, which is incorporated as a basic thermodynamic variable thus extending the space of variables of linear thermodynamics, is derived via the nonequilibrium statistical operator method. We obtain an equation of propagation of thermal waves with damping. This hyperbolic equation, which replaces Fourier's heat law removing associated inconsistencies, depends on several thermodynamic forces that include the space variation of the flux itself. The equation allows for the propagation of damped thermal excitations that are of the type of a second sound. The dispersion relation is derived with the transport coefficients given at a microscopic (mechano-statistical)level. The limiting conditions that allow to go from the damped-wave regime of propagation to the diffusive regime are discussed.

  9. THE EXTENDED OPTICAL DISK OF M101

    SciTech Connect

    Mihos, J. Christopher; Harding, Paul; Spengler, Chelsea E.; Rudick, Craig S.; Feldmeier, John J. E-mail: paul.harding@case.edu E-mail: craig.rudick@phys.ethz.ch

    2013-01-10

    We have used deep, wide-field optical imaging to study the faint outskirts of the luminous spiral galaxy M101 (NGC 5457) as well as its surrounding environment. Over 6 deg{sup 2}, our imaging has a limiting surface brightness of {mu} {sub B} {approx} 29.5 mag arcsec{sup -2}, and has revealed the stellar structure of M101's disk out to nearly 25' (50 kpc), 3 times our measured R {sub 25} isophotal size of the optical disk. At these radii, the well-known asymmetry of the inner disk slews 180 Degree-Sign , resulting in an asymmetric plume of light at large radius which follows the very extended H I disk to the northeast of M101. This plume has very blue colors (B - V {approx} 0.2), suggesting that it is the somewhat more evolved (few hundred Myr to {approx}1 Gyr) counterpart of the young far-ultraviolet emitting population traced by Galaxy Evolution Explorer imaging. We also detect another, redder spur of extended light to the east of the disk, and both structures are reminiscent of features produced during fly-by galaxy interactions. However, we see no evidence of very extended tidal tails around M101 or any of its companions which might be expected from a recent encounter with a massive companion. We consider the properties of M101's outer disk in light of possible past interactions with the nearby companion galaxies NGC 5477 and NGC 5474. The detection of optical starlight at such large radii gives us the ability to study star formation histories and stellar populations in outer disks over longer timescales than those traced by the UV or H{alpha} emitting populations. Our data suggest an ongoing buildup of M101's outer disk due to encounters in the group environment triggering extended star formation and tidal heating of existing disk populations.

  10. Cosmological dynamics of extended chameleons

    NASA Astrophysics Data System (ADS)

    Tamanini, Nicola; Wright, Matthew

    2016-04-01

    We investigate the cosmological dynamics of the recently proposed extended chameleon models at both background and linear perturbation levels. Dynamical systems techniques are employed to fully characterize the evolution of the universe at the largest distances, while structure formation is analysed at sub-horizon scales within the quasi-static approximation. The late time dynamical transition from dark matter to dark energy domination can be well described by almost all extended chameleon models considered, with no deviations from ΛCDM results at both background and perturbation levels. The results obtained in this work confirm the cosmological viability of extended chameleons as alternative dark energy models.

  11. Extended scaling in high dimensions

    NASA Astrophysics Data System (ADS)

    Berche, B.; Chatelain, C.; Dhall, C.; Kenna, R.; Low, R.; Walter, J.-C.

    2008-11-01

    We apply and test the recently proposed 'extended scaling' scheme in an analysis of the magnetic susceptibility of Ising systems above the upper critical dimension. The data are obtained by Monte Carlo simulations using both the conventional Wolff cluster algorithm and the Prokof'ev-Svistunov worm algorithm. As already observed for other models, extended scaling is shown to extend the high-temperature critical scaling regime over a range of temperatures much wider than that achieved conventionally. It allows for an accurate determination of leading and sub-leading scaling indices, critical temperatures and amplitudes of the confluent corrections.

  12. Cognitive Transformations and Extended Expertise

    ERIC Educational Resources Information Center

    Menary, Richard; Kirchhoff, Michael

    2014-01-01

    Expertise is extended by becoming immersed in cultural practices. We look at an example of mathematical expertise in which immersion in cognitive practices results in the transformation of expert performance.

  13. Consequence Analysis for Used Fuel Extended Storage

    SciTech Connect

    Dunn, Timothy; Gerhard, Michael; Sutton, Mark; Wen, Josh

    2014-09-23

    Early identification and evaluation of security issues related to the extended storage of used nuclear fuel is critical. A breach in a dry fuel storage container has the possibility of external gas from the atmosphere interacting with the used fuel rods at high temperatures, resulting in rapid oxidation and possibly the ignition of a zirconium fire. In support of this idea, the current work aims to develop a computational model of heat transfer and fluid flow in and through a breached dry fuel storage cask to determine if the resulting flow conditions are likely to result in a fire.

  14. Topological defects in extended inflation

    NASA Technical Reports Server (NTRS)

    Copeland, Edmund J.; Kolb, Edward W.; Liddle, Andrew R.

    1990-01-01

    The production of topological defects, especially cosmic strings, in extended inflation models was considered. In extended inflation, the Universe passes through a first-order phase transition via bubble percolation, which naturally allows defects to form at the end of inflation. The correlation length, which determines the number density of the defects, is related to the mean size of bubbles when they collide. This mechanism allows a natural combination of inflation and large scale structure via cosmic strings.

  15. Extender for securing a closure

    DOEpatents

    Thomas, II, Patrick A.

    2012-10-02

    An apparatus for securing a closure such as door or a window that opens and closes by movement relative to a fixed structure such as a wall or a floor. Many embodiments provide a device for relocating a padlock from its normal location where it secures a fastener (such as a hasp) to a location for the padlock that is more accessible for locking and unlocking the padlock. Typically an extender is provided, where the extender has a hook at a first end that is disposed through the eye of the staple of the hasp, and at an opposing second end the extender has an annulus, such as a hole in the extender or a loop or ring affixed to the extender. The shackle of the padlock may be disposed through the annulus and may be disposed through the eye of a second staple to secure the door or window in a closed or open position. Some embodiments employ a rigid sheath to enclose at least a portion of the extender. Typically the rigid sheath has an open state where the hook is exposed outside the sheath and a closed state where the hook is disposed within the sheath.

  16. Extended pie menus for immersive virtual environments.

    PubMed

    Gebhardt, Sascha; Pick, Sebastian; Leithold, Franziska; Hentschel, Bernd; Kuhlen, Torsten

    2013-04-01

    Pie menus are a well-known technique for interacting with 2D environments and so far a large body of research documents their usage and optimizations. Yet, comparatively little research has been done on the usability of pie menus in immersive virtual environments (IVEs). In this paper we reduce this gap by presenting an implementation and evaluation of an extended hierarchical pie menu system for IVEs that can be operated with a six-degrees-of-freedom input device. Following an iterative development process, we first developed and evaluated a basic hierarchical pie menu system. To better understand how pie menus should be operated in IVEs, we tested this system in a pilot user study with 24 participants and focus on item selection. Regarding the results of the study, the system was tweaked and elements like check boxes, sliders, and color map editors were added to provide extended functionality. An expert review with five experts was performed with the extended pie menus being integrated into an existing VR application to identify potential design issues. Overall results indicated high performance and efficient design.

  17. Extended Bose-Hubbard models with ultracold magnetic atoms.

    PubMed

    Baier, S; Mark, M J; Petter, D; Aikawa, K; Chomaz, L; Cai, Z; Baranov, M; Zoller, P; Ferlaino, F

    2016-04-08

    The Hubbard model underlies our understanding of strongly correlated materials. Whereas its standard form only comprises interactions between particles at the same lattice site, extending it to encompass long-range interactions is predicted to profoundly alter the quantum behavior of the system. We realize the extended Bose-Hubbard model for an ultracold gas of strongly magnetic erbium atoms in a three-dimensional optical lattice. Controlling the orientation of the atomic dipoles, we reveal the anisotropic character of the onsite interaction and hopping dynamics and their influence on the superfluid-to-Mott insulator quantum phase transition. Moreover, we observe nearest-neighbor interactions, a genuine consequence of the long-range nature of dipolar interactions. Our results lay the groundwork for future studies of exotic many-body quantum phases.

  18. Extended Bose-Hubbard models with ultracold magnetic atoms

    NASA Astrophysics Data System (ADS)

    Baier, S.; Mark, M. J.; Petter, D.; Aikawa, K.; Chomaz, L.; Cai, Z.; Baranov, M.; Zoller, P.; Ferlaino, F.

    2016-04-01

    The Hubbard model underlies our understanding of strongly correlated materials. Whereas its standard form only comprises interactions between particles at the same lattice site, extending it to encompass long-range interactions is predicted to profoundly alter the quantum behavior of the system. We realize the extended Bose-Hubbard model for an ultracold gas of strongly magnetic erbium atoms in a three-dimensional optical lattice. Controlling the orientation of the atomic dipoles, we reveal the anisotropic character of the onsite interaction and hopping dynamics and their influence on the superfluid-to-Mott insulator quantum phase transition. Moreover, we observe nearest-neighbor interactions, a genuine consequence of the long-range nature of dipolar interactions. Our results lay the groundwork for future studies of exotic many-body quantum phases.

  19. An Extended Keyword Extraction Method

    NASA Astrophysics Data System (ADS)

    Hong, Bao; Zhen, Deng

    Among numerous Chinese keyword extraction methods, Chinese characteristics were shortly considered. This phenomenon going against the precision enhancement of the Chinese keyword extraction. An extended term frequency based method(Extended TF) is proposed in this paper which combined Chinese linguistic characteristics with basic TF method. Unary, binary and ternary grammars for the candidate keyword extraction as well as other linguistic features were all taken into account. The method establishes classification model using support vector machine. Tests show that the proposed extraction method improved key words precision and recall rate significantly. We applied the key words extracted by the extended TF method into the text file classification. Results show that the key words extracted by the proposed method contributed greatly to raising the precision of text file classification.

  20. A novel extended state observer.

    PubMed

    Xiong, Shaofeng; Wang, Weihong; Liu, Xiaodong; Chen, Zengqiang; Wang, Sen

    2015-09-01

    A novel extended state observer, which feeds back the output estimation error via both nonlinear and switching terms, is put forward for the first time in this paper. No longer neglecting the lumped uncertainty׳s first time derivative, the problem of disturbance observer design is transformed into the problem of state observer design in the presence of external disturbance. The switching term of the output estimation error is employed to counteract the adverse effect of external disturbance. The newly developed extended state observer provides an attractive solution to the issue of high precision motion control system. Both numerical simulation and experimentation on a speed turntable with temperature box are implemented to verify the performance of the proposed newly developed extended state observer.

  1. Extended cognition in science communication.

    PubMed

    Ludwig, David

    2014-11-01

    The aim of this article is to propose a methodological externalism that takes knowledge about science to be partly constituted by the environment. My starting point is the debate about extended cognition in contemporary philosophy and cognitive science. Externalists claim that human cognition extends beyond the brain and can be partly constituted by external devices. First, I show that most studies of public knowledge about science are based on an internalist framework that excludes the environment we usually utilize to make sense of science and does not allow the possibility of extended knowledge. In a second step, I argue that science communication studies should adopt a methodological externalism and accept that knowledge about science can be partly realized by external information resources such as Wikipedia.

  2. WFRC patrners: our extended family

    USGS Publications Warehouse

    Connolly, P.; Elliot, D.; Parsley, M.; Winton, J.

    2007-01-01

    For more than five decades the Western Fisheries Research Center (WFRC) has worked with partners to provide research findings to managers of aquatic resources. Those partners form an extended family, a network of clients, colleagues, co-investigators, and customers. Our partners include numerous clients in other Department of Interior bureaus such as the U.S. Fish and Wildlife Service, the U.S. Bureau of Reclamation, and the National Park Service. But there is much more--we have partners in other federal agencies, state agencies, and universities. The extended family includes tribal governments, and non-government organizations such as the Nature Conservancy and the Lower Columbia River Estuary Program.

  3. Adjustable extender for instrument module

    DOEpatents

    Sevec, J.B.; Stein, A.D.

    1975-11-01

    A blank extender module used to mount an instrument module in front of its console for repair or test purposes has been equipped with a rotatable mount and means for locking the mount at various angles of rotation for easy accessibility. The rotatable mount includes a horizontal conduit supported by bearings within the blank module. The conduit is spring-biased in a retracted position within the blank module and in this position a small gear mounted on the conduit periphery is locked by a fixed pawl. The conduit and instrument mount can be pulled into an extended position with the gear clearing the pawl to permit rotation and adjustment of the instrument.

  4. Development of a 670 GHz Extended Interaction Klystron Power Amplifier

    DTIC Science & Technology

    2011-03-01

    th of which wi ment of EIK’ ely on lithogr ion circuits w o minimize los s that only ce lithographica ost obvious pper parts can nal distortion...ibution Unlimited interpreted as r epartment of De ts, where the R 000nm; in our ctivity of app pper , consiste tal dissipation of RF dissipa ll be largest

  5. Advances in Simulation of Wave Interaction with Extended MHD Phenomena

    SciTech Connect

    Batchelor, Donald B; Abla, Gheni; D'Azevedo, Ed F; Bateman, Glenn; Bernholdt, David E; Berry, Lee A; Bonoli, P.; Bramley, R; Breslau, Joshua; Chance, M.; Chen, J.; Choi, M.; Elwasif, Wael R; Foley, S.; Fu, GuoYong; Harvey, R. W.; Jaeger, Erwin Frederick; Jardin, S. C.; Jenkins, T; Keyes, David E; Klasky, Scott A; Kruger, Scott; Ku, Long-Poe; Lynch, Vickie E; McCune, Douglas; Ramos, J.; Schissel, D.; Schnack,; Wright, J.

    2009-01-01

    The Integrated Plasma Simulator (IPS) provides a framework within which some of the most advanced, massively-parallel fusion modeling codes can be interoperated to provide a detailed picture of the multi-physics processes involved in fusion experiments. The presentation will cover four topics: 1) recent improvements to the IPS, 2) application of the IPS for very high resolution simulations of ITER scenarios, 3) studies of resistive and ideal MHD stability in tokamk discharges using IPS facilities, and 4) the application of RF power in the electron cyclotron range of frequencies to control slowly growing MHD modes in tokamaks and initial evaluations of optimized location for RF power deposition.

  6. Advances in Simulation of Wave Interactions with Extended MHD Phenomena

    SciTech Connect

    Batchelor, Donald B; D'Azevedo, Eduardo; Bateman, Glenn; Bernholdt, David E; Bonoli, P.; Bramley, Randall B; Breslau, Joshua; Elwasif, Wael R; Foley, S.; Jaeger, Erwin Frederick; Jardin, S. C.; Klasky, Scott A; Kruger, Scott E; Ku, Long-Poe; McCune, Douglas; Ramos, J.; Schissel, David P; Schnack, Dalton D

    2009-01-01

    The Integrated Plasma Simulator (IPS) provides a framework within which some of the most advanced, massively-parallel fusion modeling codes can be interoperated to provide a detailed picture of the multi-physics processes involved in fusion experiments. The presentation will cover four topics: (1) recent improvements to the IPS, (2) application of the IPS for very high resolution simulations of ITER scenarios, (3) studies of resistive and ideal MHD stability in tokamak discharges using IPS facilities, and (4) the application of RF power in the electron cyclotron range of frequencies to control slowly growing MHD modes in tokamaks and initial evaluations of optimized location for RF power deposition.

  7. Lightweight extendable and retractable pole

    DOEpatents

    Warren, J.L.; Brandt, J.E.

    1994-08-02

    A lightweight extendable and retractable telescopic pole is disclosed comprising a plurality of non-metallic telescoping cylinders with sliding and sealing surfaces between the cylinders, a first plug member on the upper end of the smallest cylinder, and a second plug member on the lower end of the largest cylinder, whereby fluid pressure admitted to the largest cylinder will cause the telescoping cylinders to slide relative to one another causing the pole to extend. An elastomeric member connects the first plug member with one of the intermediate cylinders to urge the cylinders back into a collapsed position when the fluid pressure in the cylinders is vented. Annular elastomer members are provided which seal one cylinder to another when the pole is fully extended and further serve to provide a cushion to prevent damage to the cylinders when the pole is urged back into its retractable position by the elastomeric members and the venting of the pressure. A value mechanism associated with the pole is provided to admit a fluid under pressure to the interior of the telescoping cylinders of the pole while pressurizing a pressure relief port having an opening larger than the inlet port in a closed position whereby removal of the pressure on the relief port will cause the relief port to open to quickly lower the pressure in the interior of the telescoping cylinders to thereby assist in the rapid retraction of the extended pole. 18 figs.

  8. Lightweight extendable and retractable pole

    DOEpatents

    Warren, John L.; Brandt, James E.

    1994-01-01

    A lightweight extendable and retractable telescopic pole is disclosed comprising a plurality of non-metallic telescoping cylinders with sliding and sealing surfaces between the cylinders, a first plug member on the upper end of the smallest cylinder, and a second plug member on the lower end of the largest cylinder, whereby fluid pressure admitted to the largest cylinder will cause the telescoping cylinders to slide relative to one another causing the pole to extend. An elastomeric member connects the first plug member with one of the intermediate cylinders to urge the cylinders back into a collapsed position when the fluid pressure in the cylinders is vented. Annular elastomer members are provided which seal one cylinder to another when the pole is fully extended and further serve to provide a cushion to prevent damage to the cylinders when the pole is urged back into its retractable position by the elastomeric members and the venting of the pressure. A value mechanism associated with the pole is provided to admit a fluid under pressure to the interior of the telescoping cylinders of the pole while pressurizing a pressure relief port having an opening larger than the inlet port in a closed position whereby removal of the pressure on the relief port will cause the relief port to open to quickly lower the pressure in the interior of the telescoping cylinders to thereby assist in the rapid retraction of the extended pole.

  9. Extended range chemical sensing apparatus

    DOEpatents

    Hughes, Robert C.; Schubert, W. Kent

    1994-01-01

    An apparatus for sensing chemicals over extended range of concentrations. In particular, first and second sensors each having separate, but overlapping ranges for sensing concentrations of hydrogen are provided. Preferably, the first sensor is a MOS solid state device wherein the metal electrode or gate is a nickel alloy. The second sensor is a chemiresistor comprising a nickel alloy.

  10. Rigid gas permeable extended wear.

    PubMed

    Maehara, J R; Kastl, P R

    1994-04-01

    We have reviewed the pertinent literature on rigid gas permeable (RGP) extended wear contact lenses, and we discuss the benefits and adverse reactions of this contact lens modality, drawing conclusions from reviewed studies. We suggest parameters for success with these lenses and guidelines for the prevention of adverse reactions.

  11. Group Development: Extending Tuckman's Theory.

    ERIC Educational Resources Information Center

    Maples, Mary F.

    1988-01-01

    Presents a framework for extending the Tuckman model of developmental sequence in small groups. Considers Tuckman's stages of forming, storming, norming, performing, and adjourning lacking in descriptive depth and clear definition. Gathered and organized group dynamics graduate students' assessments of characteristics of stages over five-year…

  12. Extending the Internet 2 Domain.

    ERIC Educational Resources Information Center

    Simco, Greg

    2002-01-01

    Discussion of the Internet 2 community, formed from partnerships involving universities, businesses, and the government, focuses on the K-20 Initiative that extends Internet 2 developments to other nonmember environments, including elementary and secondary schools, community colleges, universities, libraries, and museums. Discusses networking and…

  13. Extended range chemical sensing apparatus

    DOEpatents

    Hughes, R.C.; Schubert, W.K.

    1994-01-18

    An apparatus is described for sensing chemicals over extended range of concentrations. In particular, first and second sensors each having separate, but overlapping ranges for sensing concentrations of hydrogen are provided. Preferably, the first sensor is a MOS solid state device wherein the metal electrode or gate is a nickel alloy. The second sensor is a chemiresistor comprising a nickel alloy. 6 figures.

  14. Engage, Enhance, and Extend Learning!

    ERIC Educational Resources Information Center

    Keren-Kolb, Liz

    2013-01-01

    Educators often say that technology is more than a gimmick or add-on, and that it should engage, enhance, or extend learning in ways that traditional tools do not. Yet they seldom stop to define these terms, and they can be confusing, especially for teachers and preservice teachers. Recently, while collaborating on an English language arts and…

  15. Extended mind and after: socially extended mind and actor-network.

    PubMed

    Kono, Tetsuya

    2014-03-01

    The concept of extended mind has been impressively developed over the last 10 years by many philosophers and cognitive scientists. The extended mind thesis (EM) affirms that the mind is not simply ensconced inside the head, but extends to the whole system of brain-body-environment. Recently, some philosophers and psychologists try to adapt the idea of EM to the domain of social cognition research. Mind is socially extended (SEM). However, EM/SEM theory has problems to analyze the interactions among a subject and its surroundings with opposition, antagonism, or conflict; it also tends to think that the environment surrounding the subject is passive or static, and to neglect the power of non-human actants to direct and regulate the human subject. In these points, actor-network theory (ANT) proposed by Latour and Callon is more persuasive, while sharing some important ideas with EM/SEM theory. Actor-network is a hybrid community which is composed of a series of heterogeneous elements, animate and inanimate for a certain period of time. I shall conclude that EM/SEM could be best analyzed as a special case of actor-network. EM/SEM is a system which can be controlled by a human agent alone. In order to understand collective behavior, philosophy and psychology have to study the actor-network in which human individuals are situated.

  16. Extended GTST-MLD for aerospace system safety analysis.

    PubMed

    Guo, Chiming; Gong, Shiyu; Tan, Lin; Guo, Bo

    2012-06-01

    The hazards caused by complex interactions in the aerospace system have become a problem that urgently needs to be settled. This article introduces a method for aerospace system hazard interaction identification based on extended GTST-MLD (goal tree-success tree-master logic diagram) during the design stage. GTST-MLD is a functional modeling framework with a simple architecture. Ontology is used to extend the ability of system interaction description in GTST-MLD by adding the system design knowledge and the past accident experience. From the level of functionality and equipment, respectively, this approach can help the technician detect potential hazard interactions. Finally, a case is used to show the method.

  17. FIRE I - Extended Time Observations Data Sets

    Atmospheric Science Data Center

    2013-08-01

    FIRE I - Extended Time Observations Data Sets First ISCCP Regional Experiment (FIRE) I - Extended Time Observations were conducted in Utah. Relevant Documents:  FIRE Project Guide FIRE I - Extended Time Observations Home Page SCAR-B Block:  ...

  18. AWIPS II Extended - Data Delivery

    NASA Astrophysics Data System (ADS)

    Henry, R.; Schotz, S.; Calkins, J.; Gockel, B.; Ortiz, C.; Peter, R.

    2012-12-01

    AWIPS II Technology Infusion is a multiphase program. The first phase is the migration of the Weather Forecast Offices (WFOs) and River Forecast Centers (RFCs) AWIPS I capabilities into a Service Oriented Architecture (SOA), referred to as AWIPS II. AWIPS II is currently being deployed to Operational Test and Evaluation (OTE) and other select deployment sites. The subsequent phases of AWIPS Technology Infusion, known as AWIPS II Extended, include several projects that will improve technological capabilities of AWIPS II in order to enhance the NWS enterprise and improve services to partners. This paper summarizes AWIPS II Extended - Data Delivery project and reports on its status. Data Delivery enables AWIPS II users to discover, subscribe and access web-enabled data provider systems including the capability to subset datasets by space, time and parameter.

  19. Predictability in the extended range

    NASA Technical Reports Server (NTRS)

    Roads, John O.

    1987-01-01

    This paper describes the results of extended range predictability experiments using an efficient two-level spherical quasi-geostrophic model. The experiments have an initial rms doubling time of about two days. This growth rate, along with an initial error of about one-half the initial error of present operational models, produces an rms error equal to the climatological rms error and a correlation of 0.5 on about day 12 of the forecast. On the largest scales, this limiting point is reached shortly thereafter. The error continues to grow at a decreasing rate until at about 30 days the forecast skill is extremely small and comparable to the skill of a persistence forecast. Various time averages at various lags are examined for skill in the extended range. Filters that weighted most strongly in the initial forecast days provide increased skill.

  20. ESA extends solar observatory mission

    NASA Astrophysics Data System (ADS)

    Zielinski, Sarah

    2006-06-01

    The European Space Agency (ESA) announced on 24 May that it would extend the life of its Solar and Heliospheric Observatory (SOHO) from April 2007 to December 2009. Since it was launched in December 1995, SOHO has provided scientists with a view of the Sun's surface. ``This mission extension will allow SOHO to cement its position as the most important spacecraft in the history of solar physics,'' said SOHO project scientist Bernhard Fleck.

  1. VideoANT: Extending Online Video Annotation beyond Content Delivery

    ERIC Educational Resources Information Center

    Hosack, Bradford

    2010-01-01

    This paper expands the boundaries of video annotation in education by outlining the need for extended interaction in online video use, identifying the challenges faced by existing video annotation tools, and introducing Video-ANT, a tool designed to create text-based annotations integrated within the time line of a video hosted online. Several…

  2. Spin transport in intermediate-energy heavy-ion collisions as a probe of in-medium spin-orbit interactions

    NASA Astrophysics Data System (ADS)

    Xia, Yin; Xu, Jun; Li, Bao-An; Shen, Wen-Qing

    2016-11-01

    The spin up-down splitting of collective flows in intermediate-energy heavy-ion collisions as a result of the nuclear spin-orbit interaction is investigated within a spin- and isospin-dependent Boltzmann-Uehling-Uhlenbeck transport model SIBUU12. Using a Skyrme-type spin-orbit coupling quadratic in momentum, we found that the spin splittings of the directed flow and elliptic flow are largest in peripheral Au+Au collisions at beam energies of about 100-200 MeV/nucleon, and the effect is considerable even in smaller systems especially for nucleons with high transverse momenta. The collective flows of light clusters of different spin states are also investigated using an improved dynamical coalescence model with spin. Our study can be important in understanding the properties of in-medium nuclear spin-orbit interactions once the spin-dependent observables proposed in this work can be measured.

  3. Extending lithography with advanced materials

    NASA Astrophysics Data System (ADS)

    Guerrero, Douglas J.

    2014-03-01

    Material evolution has been a key enabler of lithography nodes in the last 30 years. This paper explores the evolution of anti-reflective coatings and their transformation from materials that provide only reflection control to advanced multifunctional layers. It is expected that complementary processes that do not require a change in wavelength will continue to dominate the development of new devices and technology nodes. New device architecture, immersion lithography, negative-tone development, multiple patterning, and directed self-assembly have demonstrated the capabilities of extending lithography nodes beyond what anyone thought would be possible. New material advancements for future technology nodes are proposed.

  4. Conversion and optimization of the parameters from an extended form of the ion-interaction model for Ca(NO3)2(aq) and NaNO3(aq) to those of the standard Pitzer model, and an assessment of the accuracy of the parameter temperature representations

    SciTech Connect

    Wijesinghe, A M; Rard, J A

    2004-12-21

    The electrolytes Ca(NO{sub 3}){sub 2}(aq) and NaNO{sub 3}(aq) are both extremely soluble but differ in several important respects. Ca(NO{sub 3}){sub 2}(aq) has complex behavior at low ionic strengths and forms several thermodynamically stable and metastable solid phases, whereas NaNO{sub 3}(aq) forms only an anhydrous solid phase. The thermodynamic properties of both have previously been modeled using extended Pitzer ion-interaction models that include higher-order virial terms, in addition to those of the standard Pitzer model. The parameters of the original Pitzer model, however, are often needed for thermodynamic modeling calculations. In this paper we convert the parameters of the extended ion-interaction models for Ca(NO{sub 3}){sub 2}(aq) and NaNO{sub 3}(aq) to the standard Pitzer model using an extension of the methodology previously described by Rard and Wijesinghe [J. Chem. Thermodynamics 35 (2003) 439.473]. In this variant, the exponential coefficient {alpha}{sub 1}{sup P} of Pitzer's model is also optimized to yield the most accurate overall representation of the osmotic coefficients {phi} over the ionic strength and temperature ranges of interest. The optimal values of {alpha}{sub 1}{sup P} = 0.87 kg{sup 1/2} {center_dot} mol{sup -1/2} for Ca(NO{sub 3}){sub 2}(aq) and {alpha}{sub 1}{sup P} = 1.43 kg{sup 1/2} {center_dot} mol{sup -1/2} for NaNO{sub 3}(aq) are smaller than the value {alpha}{sub 1}{sup P} = 2.00 kg{sup 1/2} {center_dot} mol{sup -1/2} normally used for electrolytes of these valence types. In both cases, the accuracy of the osmotic coefficients predicted by the standard Pitzer model was nearly equal to that of the extended Pitzer model up to the solubility limit for T = (298.15 to 423.15) K. This result is consistent with the findings of Rard, Wijesinghe, and Wolery [J. Chem. Eng. Data 49 (2004) 1127-1140] who obtained a substantial improvement in model accuracy for Mg(NO{sub 3}){sub 2}(aq) at T = 298.15 K by optimizing this parameter. The

  5. 38 CFR 21.57 - Extended evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Extended evaluation. 21... Initial and Extended Evaluation § 21.57 Extended evaluation. (a) Purpose. The purpose of an extended evaluation for a veteran with a serious employment handicap is to determine the current feasibility of...

  6. Regularization of zero-range effective interactions in finite nuclei

    NASA Astrophysics Data System (ADS)

    Brenna, Marco; Colò, Gianluca; Roca-Maza, Xavier

    2014-10-01

    The problem of the divergences which arise in beyond mean-field calculations, when a zero-range effective interaction is employed, has not been much considered so far. Some of us have proposed, quite recently, a scheme to regularize a zero-range Skyrme-type force when it is employed to calculate the total energy, at second-order perturbation theory level, in uniform matter. Although this scheme looked promising, the extension for finite nuclei is not straightforward. We introduce such a procedure in the current paper, by proposing a regularization procedure that is similar, in spirit, to the one employed to extract the so-called Vlow-k from the bare force. Although this has been suggested already by B. G. Carlsson and collaborators, the novelty of our work consists of setting on equal footing uniform matter and finite nuclei; in particular, we show how the interactions that have been regularized in uniform matter behave when they are used in a finite nucleus with the corresponding cutoff. We also address the problem of the validity of the perturbative approach in finite nuclei for the total energy.

  7. Extended Operation of Stirling Convertors

    NASA Technical Reports Server (NTRS)

    Roth, Mary Ellen; Schreiber, Jeffery G.; Pepper, Stephen V.

    2004-01-01

    A high-efficiency 110 W Stirling Radioisotope Generator 110 (SRG110) is being developed for potential NASA exploration missions. The SRG system efficiency is greater than 20%, making it an attractive candidate power system for deep space missions and unmanned rovers. The Department of Energy SRG110 Project team consists of the System Integrator, Lockheed Martin (LM), Stirling Technology Company (STC), and NASA Glenn Research Center (GRC). One of the GRC roles is to provide Independent Verification and Validation of the Stirling TDC s. At the request of LM, a part of this effort includes the Extended Operation of the TDC s in the dynamically balanced dual-opposed configuration. Performance data of Stirling Convertors over time is required to demonstrate that an SRG110 can meet long-duration mission requirements. A test plan and test system were developed to evaluate TDC s #13 and #14 steady-state performance for a minimum of 5000 hours. Hardware, software and TDC preparation processes were developed to support this test and insure safe, round-the-clock operation of the TDC s. This paper will discuss the design and development, and status of the Extended Operation Test.

  8. Pipe crawler with extendable legs

    DOEpatents

    Zollinger, W.T.

    1992-06-16

    A pipe crawler for moving through a pipe in inchworm fashion having front and rear leg assemblies separated by air cylinders to increase and decrease the spacing between assemblies. Each leg of the four legs of an assembly is moved between a wall-engaging, extended position and a retracted position by a separate air cylinder. The air cylinders of the leg assemblies are preferably arranged in pairs of oppositely directed cylinders with no pair lying in the same axial plane as another pair. Therefore, the cylinders can be as long as a leg assembly is wide and the crawler can crawl through sections of pipes where the diameter is twice that of other sections. The crawler carries a valving system, a manifold to distribute air supplied by a single umbilical air hose to the various air cylinders in a sequence controlled electrically by a controller. The crawler also utilizes a rolling mechanism, casters in this case, to reduce friction between the crawler and pipe wall thereby further extending the range of the pipe crawler. 8 figs.

  9. Extended suicide with a pet.

    PubMed

    Cooke, Brian K

    2013-01-01

    The combination of the killing of a pet and a suicide is a perplexing scenario that is largely unexplored in the literature. Many forensic psychiatrists and psychologists may be unaccustomed to considering the significance of the killing of a pet. The subject is important, however, because many people regard their pets as members of their family. A case is presented of a woman who killed her pet dog and herself by carbon monoxide poisoning. The purpose of this article is to provide an initial exploration of the topic of extended suicide with a pet. Forensic mental health evaluations may have a role in understanding the etiology of this event and in opining as to the culpability of individuals who attempt to or successfully kill a pet and then commit suicide. Because the scientific literature is lacking, there is a need to understand this act from a variety of perspectives. First, a social and anthropological perspective will be presented that summarizes the history of the practice of killing of one's pet, with a focus on the ancient Egyptians. A clinical context will examine what relationship animals have to mental illness. A vast body of existing scientific data showing the relevance of human attachment to pets suggests that conclusions from the phenomena of homicide-suicide and filicide-suicide are applicable to extended suicide with a pet. Finally, recommendations will be proposed for both clinical and forensic psychiatrists faced with similar cases.

  10. Extended Operation of Stirling Convertors

    NASA Technical Reports Server (NTRS)

    Roth, Mary Ellen; Schreiber, Jeffrey G.; Pepper, Stephen V.

    2004-01-01

    A high-efficiency 110 watt Stirling Radioisotope Generator 110 (SRG110) is being developed for potential NASA exploration missions. The SRG system efficiency is greater than 20%, making it an attractive candidate power system for deep space missions and unmanned rovers. The Department of Energy SRG110 Project team consists of the System Integrator, Lockheed Martin (LM), Stirling Technology Company (STC), and NASA Glenn Research Center (GRC). One of the GRC roles is to provide Independent Verification and Validation of the Stirling TDC's. At the request of LM, a part of this effort includes the extended operation of the TDC's in the dynamically balanced dual-opposed configuration. Performance data of the Stirling Converters over time is required to demonstrate that an SRG110 can meet long-duration mission requirements. A test plan and test system were developed to evaluate TDC's #13 and #14 steady-state performance for a minimum of 5000 hours and insure safe, round-the-clock operation of the TDC's. This paper will discuss the design and development, and status of the Extended Operation Test.

  11. Pipe crawler with extendable legs

    DOEpatents

    Zollinger, William T.

    1992-01-01

    A pipe crawler for moving through a pipe in inchworm fashion having front and rear leg assemblies separated by air cylinders to increase and decrease the spacing between assemblies. Each leg of the four legs of an assembly is moved between a wall-engaging, extended position and a retracted position by a separate air cylinder. The air cylinders of the leg assemblies are preferably arranged in pairs of oppositely directed cylinders with no pair lying in the same axial plane as another pair. Therefore, the cylinders can be as long a leg assembly is wide and the crawler can crawl through sections of pipes where the diameter is twice that of other sections. The crawler carries a valving system, a manifold to distribute air supplied by a single umbilical air hose to the various air cylinders in a sequence controlled electrically by a controller. The crawler also utilizes a rolling mechanism, casters in this case, to reduce friction between the crawler and pipe wall thereby further extending the range of the pipe crawler.

  12. Extended Duration Orbiter Medical Project

    NASA Technical Reports Server (NTRS)

    Sawin, Charles F. (Editor); Taylor, Gerald R. (Editor); Smith, Wanda L. (Editor); Brown, J. Travis (Technical Monitor)

    1999-01-01

    Biomedical issues have presented a challenge to flight physicians, scientists, and engineers ever since the advent of high-speed, high-altitude airplane flight in the 1940s. In 1958, preparations began for the first manned space flights of Project Mercury. The medical data and flight experience gained through Mercury's six flights and the Gemini, Apollo, and Skylab projects, as well as subsequent space flights, comprised the knowledge base that was used to develop and implement the Extended Duration Orbiter Medical Project (EDOMP). The EDOMP yielded substantial amounts of data in six areas of space biomedical research. In addition, a significant amount of hardware was developed and tested under the EDOMP. This hardware was designed to improve data gathering capabilities and maintain crew physical fitness, while minimizing the overall impact to the microgravity environment. The biomedical findings as well as the hardware development results realized from the EDOMP have been important to the continuing success of extended Space Shuttle flights and have formed the basis for medical studies of crew members living for three to five months aboard the Russian space station, Mir. EDOMP data and hardware are also being used in preparation for the construction and habitation of International Space Station. All data sets were grouped to be non-attributable to individuals, and submitted to NASA s Life Sciences Data Archive.

  13. Extended recombinant bacterial ghost system.

    PubMed

    Lubitz, W; Witte, A; Eko, F O; Kamal, M; Jechlinger, W; Brand, E; Marchart, J; Haidinger, W; Huter, V; Felnerova, D; Stralis-Alves, N; Lechleitner, S; Melzer, H; Szostak, M P; Resch, S; Mader, H; Kuen, B; Mayr, B; Mayrhofer, P; Geretschläger, R; Haslberger, A; Hensel, A

    1999-08-20

    Controlled expression of cloned PhiX174 gene E in Gram-negative bacteria results in lysis of the bacteria by formation of an E-specific transmembrane tunnel structure built through the cell envelope complex. Bacterial ghosts from a variety of bacteria are used as non-living candidate vaccines. In the recombinant ghost system, foreign proteins are attached on the inside of the inner membrane as fusions with specific anchor sequences. Ghosts have a sealed periplasmic space and the export of proteins into this space vastly extends the capacity of ghosts or recombinant ghosts to function as carriers of foreign antigens. In addition, S-layer proteins forming shell-like self assembly structures can be expressed in candidate vaccine strains prior to E-mediated lysis. Such recombinant S-layer proteins carrying foreign epitopes further extend the possibilities of ghosts as carriers of foreign epitopes. As ghosts have inherent adjuvant properties, they can be used as adjuvants in combination with subunit vaccines. Subunits or other ligands can also be coupled to matrixes like dextran which are used to fill the internal lumen of ghosts. Oral, aerogenic or parenteral immunization of experimental animals with recombinant ghosts induced specific humoral and cellular immune responses against bacterial and target components including protective mucosal immunity. The most relevant advantage of recombinant bacterial ghosts as immunogens is that no inactivation procedures that denature relevant immunogenic determinants are employed in this production. This fact explains the superior quality of ghosts when compared to other inactivated vaccines. The endotoxic component of the outer membrane does not limit the use of ghosts as vaccine candidates but triggers the release of several potent immunoregulatory cytokines. As carriers, there is no limitation in the size of foreign antigens that can be inserted in the membrane and the capacity of all spaces including the membranes, peri

  14. Learning Extended Finite State Machines

    NASA Technical Reports Server (NTRS)

    Cassel, Sofia; Howar, Falk; Jonsson, Bengt; Steffen, Bernhard

    2014-01-01

    We present an active learning algorithm for inferring extended finite state machines (EFSM)s, combining data flow and control behavior. Key to our learning technique is a novel learning model based on so-called tree queries. The learning algorithm uses the tree queries to infer symbolic data constraints on parameters, e.g., sequence numbers, time stamps, identifiers, or even simple arithmetic. We describe sufficient conditions for the properties that the symbolic constraints provided by a tree query in general must have to be usable in our learning model. We have evaluated our algorithm in a black-box scenario, where tree queries are realized through (black-box) testing. Our case studies include connection establishment in TCP and a priority queue from the Java Class Library.

  15. Stellar structures in Extended Gravity

    NASA Astrophysics Data System (ADS)

    Capozziello, S.; De Laurentis, M.

    2016-09-01

    Stellar structures are investigated by considering the modified Lané-Emden equation coming out from Extended Gravity. In particular, this equation is obtained in the Newtonian limit of f ( R) -gravity by introducing a polytropic relation between the pressure and the density into the modified Poisson equation. The result is an integro-differential equation, which, in the limit f ( R) → R , becomes the standard Lané-Emden equation usually adopted in the stellar theory. We find the radial profiles of gravitational potential by solving for some values of the polytropic index. The solutions are compatible with those coming from General Relativity and could be physically relevant in order to address peculiar and extremely massive objects.

  16. Extended thermodynamics of dense gases

    NASA Astrophysics Data System (ADS)

    Arima, T.; Taniguchi, S.; Ruggeri, T.; Sugiyama, M.

    2012-11-01

    We study extended thermodynamics of dense gases by adopting the system of field equations with a different hierarchy structure to that adopted in the previous works. It is the theory of 14 fields of mass density, velocity, temperature, viscous stress, dynamic pressure, and heat flux. As a result, most of the constitutive equations can be determined explicitly by the caloric and thermal equations of state. It is shown that the rarefied-gas limit of the theory is consistent with the kinetic theory of gases. We also analyze three physically important systems, that is, a gas with the virial equations of state, a hard-sphere system, and a van der Waals fluid, by using the general theory developed in the former part of the present work.

  17. Extended optical model for fission

    SciTech Connect

    Sin, M.; Capote, R.; Herman, M. W.; Trkov, A.

    2016-03-07

    A comprehensive formalism to calculate fission cross sections based on the extension of the optical model for fission is presented. It can be used for description of nuclear reactions on actinides featuring multi-humped fission barriers with partial absorption in the wells and direct transmission through discrete and continuum fission channels. The formalism describes the gross fluctuations observed in the fission probability due to vibrational resonances, and can be easily implemented in existing statistical reaction model codes. The extended optical model for fission is applied for neutron induced fission cross-section calculations on 234,235,238U and 239Pu targets. A triple-humped fission barrier is used for 234,235U(n,f), while a double-humped fission barrier is used for 238U(n,f) and 239Pu(n,f) reactions as predicted by theoretical barrier calculations. The impact of partial damping of class-II/III states, and of direct transmission through discrete and continuum fission channels, is shown to be critical for a proper description of the measured fission cross sections for 234,235,238U(n,f) reactions. The 239Pu(n,f) reaction can be calculated in the complete damping approximation. Calculated cross sections for 235,238U(n,f) and 239Pu(n,f) reactions agree within 3% with the corresponding cross sections derived within the Neutron Standards least-squares fit of available experimental data. Lastly, the extended optical model for fission can be used for both theoretical fission studies and nuclear data evaluation.

  18. Extended optical model for fission

    DOE PAGES

    Sin, M.; Capote, R.; Herman, M. W.; ...

    2016-03-07

    A comprehensive formalism to calculate fission cross sections based on the extension of the optical model for fission is presented. It can be used for description of nuclear reactions on actinides featuring multi-humped fission barriers with partial absorption in the wells and direct transmission through discrete and continuum fission channels. The formalism describes the gross fluctuations observed in the fission probability due to vibrational resonances, and can be easily implemented in existing statistical reaction model codes. The extended optical model for fission is applied for neutron induced fission cross-section calculations on 234,235,238U and 239Pu targets. A triple-humped fission barrier ismore » used for 234,235U(n,f), while a double-humped fission barrier is used for 238U(n,f) and 239Pu(n,f) reactions as predicted by theoretical barrier calculations. The impact of partial damping of class-II/III states, and of direct transmission through discrete and continuum fission channels, is shown to be critical for a proper description of the measured fission cross sections for 234,235,238U(n,f) reactions. The 239Pu(n,f) reaction can be calculated in the complete damping approximation. Calculated cross sections for 235,238U(n,f) and 239Pu(n,f) reactions agree within 3% with the corresponding cross sections derived within the Neutron Standards least-squares fit of available experimental data. Lastly, the extended optical model for fission can be used for both theoretical fission studies and nuclear data evaluation.« less

  19. The Extended Virgo Cluster Catalog

    NASA Astrophysics Data System (ADS)

    Rey, Soo-Chang

    2015-08-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg2 or 60.1 Mpc2. It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s-1. In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths.

  20. The Extended Virgo Cluster Catalog

    NASA Astrophysics Data System (ADS)

    Kim, Suk; Rey, Soo-Chang; Jerjen, Helmut; Lisker, Thorsten; Sung, Eon-Chang; Lee, Youngdae; Chung, Jiwon; Pak, Mina; Yi, Wonhyeong; Lee, Woong

    2014-12-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg2 or 60.1 Mpc2. It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s-1. In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths.

  1. Extended optical model for fission

    NASA Astrophysics Data System (ADS)

    Sin, M.; Capote, R.; Herman, M. W.; Trkov, A.

    2016-03-01

    A comprehensive formalism to calculate fission cross sections based on the extension of the optical model for fission is presented. It can be used for description of nuclear reactions on actinides featuring multi-humped fission barriers with partial absorption in the wells and direct transmission through discrete and continuum fission channels. The formalism describes the gross fluctuations observed in the fission probability due to vibrational resonances, and can be easily implemented in existing statistical reaction model codes. The extended optical model for fission is applied for neutron induced fission cross-section calculations on 234,235,238U and 239Pu targets. A triple-humped fission barrier is used for U,235234(n ,f ) , while a double-humped fission barrier is used for 238U(n ,f ) and 239Pu(n ,f ) reactions as predicted by theoretical barrier calculations. The impact of partial damping of class-II/III states, and of direct transmission through discrete and continuum fission channels, is shown to be critical for a proper description of the measured fission cross sections for 234,235,238U(n ,f ) reactions. The 239Pu(n ,f ) reaction can be calculated in the complete damping approximation. Calculated cross sections for U,238235(n ,f ) and 239Pu(n ,f ) reactions agree within 3% with the corresponding cross sections derived within the Neutron Standards least-squares fit of available experimental data. The extended optical model for fission can be used for both theoretical fission studies and nuclear data evaluation.

  2. THE EXTENDED VIRGO CLUSTER CATALOG

    SciTech Connect

    Kim, Suk; Rey, Soo-Chang; Lee, Youngdae; Chung, Jiwon; Pak, Mina; Yi, Wonhyeong; Lee, Woong; Jerjen, Helmut; Lisker, Thorsten; Sung, Eon-Chang

    2015-01-01

    We present a new catalog of galaxies in the wider region of the Virgo cluster, based on the Sloan Digital Sky Survey (SDSS) Data Release 7. The Extended Virgo Cluster Catalog (EVCC) covers an area of 725 deg{sup 2} or 60.1 Mpc{sup 2}. It is 5.2 times larger than the footprint of the classical Virgo Cluster Catalog (VCC) and reaches out to 3.5 times the virial radius of the Virgo cluster. We selected 1324 spectroscopically targeted galaxies with radial velocities less than 3000 km s{sup –1}. In addition, 265 galaxies that have been overlooked in the SDSS spectroscopic survey but have available redshifts in the NASA Extragalactic Database are also included. Our selection process secured a total of 1589 galaxies, 676 of which are not included in the VCC. The certain and possible cluster members are defined by means of redshift comparison with a cluster infall model. We employed two independent and complementary galaxy classification schemes: the traditional morphological classification based on the visual inspection of optical images and a characterization of galaxies from their spectroscopic features. SDSS u, g, r, i, and z passband photometry of all EVCC galaxies was performed using Source Extractor. We compare the EVCC galaxies with the VCC in terms of morphology, spatial distribution, and luminosity function. The EVCC defines a comprehensive galaxy sample covering a wider range in galaxy density that is significantly different from the inner region of the Virgo cluster. It will be the foundation for forthcoming galaxy evolution studies in the extended Virgo cluster region, complementing ongoing and planned Virgo cluster surveys at various wavelengths.

  3. The competition of particle-vibration coupling and tensor interaction in spherical nuclei

    NASA Astrophysics Data System (ADS)

    Afanasjev, Anatoli; Litvinova, Elena

    2014-09-01

    The search for missing terms in the energy density functionals (EDF) is one of the leading directions in the development of nuclear density functional theory (DFT). Tensor force is one of possible candidates. However, despite extensive studies the questions about its effective strength and unambiguous signals still remain open. One of the main experimental benchmarks for the studies of tensor interaction is provided by the data on the single-particle states in the N = 82 and Z = 50 isotopes. The energy splittings of the proton h11 / 2 and g7 / 2 states in the Z = 50 isotopes and neutron 1i13 / 2 and 1h9 / 2 states in the N = 82 isotones are used in the definition of tensor force in the Skyrme DFT. However, in experiment these states are not ``mean-field'' states because of coupling with vibrations. Employing relativistic particle-vibration coupling (PVC) model we show that many features of these splittings can be reproduced when PVC is taken into account. This suggests the competition of PVC and tensor interaction and that tensor interaction should be weaker as compared with previous estimates. The search for missing terms in the energy density functionals (EDF) is one of the leading directions in the development of nuclear density functional theory (DFT). Tensor force is one of possible candidates. However, despite extensive studies the questions about its effective strength and unambiguous signals still remain open. One of the main experimental benchmarks for the studies of tensor interaction is provided by the data on the single-particle states in the N = 82 and Z = 50 isotopes. The energy splittings of the proton h11 / 2 and g7 / 2 states in the Z = 50 isotopes and neutron 1i13 / 2 and 1h9 / 2 states in the N = 82 isotones are used in the definition of tensor force in the Skyrme DFT. However, in experiment these states are not ``mean-field'' states because of coupling with vibrations. Employing relativistic particle-vibration coupling (PVC) model we show that

  4. Quantum gravity kinematics from extended TQFTs

    NASA Astrophysics Data System (ADS)

    Dittrich, Bianca; Geiller, Marc

    2017-01-01

    In this paper, we show how extended topological quantum field theories (TQFTs) can be used to obtain a kinematical setup for quantum gravity, i.e. a kinematical Hilbert space together with a representation of the observable algebra including operators of quantum geometry. In particular, we consider the holonomy-flux algebra of (2 + 1)-dimensional Euclidean loop quantum gravity, and construct a new representation of this algebra that incorporates a positive cosmological constant. The vacuum state underlying our representation is defined by the Turaev-Viro TQFT. This vacuum state can be thought of as being peaked on connections with homogeneous curvature. We therefore construct here a generalization, or more precisely a quantum deformation at root of unity, of the previously introduced SU(2) BF representation. The extended Turaev-Viro TQFT provides a description of the excitations on top of the vacuum. These curvature and torsion excitations are classified by the Drinfeld center category of the quantum deformation of SU(2), and are essential in order to allow for a representation of the holonomies and fluxes. The holonomies and fluxes are generalized to ribbon operators which create and interact with the excitations. These excitations agree with the ones induced by massive and spinning particles, and therefore the framework presented here allows automatically for a description of the coupling of such matter to (2+1)-dimensional gravity with a cosmological constant. The new representation constructed here presents a number of advantages over the representations which exist so far. In particular, it possesses a very useful finiteness property which guarantees the discreteness of spectra for a wide class of quantum (intrinsic and extrinsic) geometrical operators. Also, the notion of basic excitations leads to a so-called fusion basis which offers exciting possibilities for the construction of states with interesting global properties, as well as states with certain

  5. Bioconvection in spatially extended domains

    NASA Astrophysics Data System (ADS)

    Karimi, A.; Paul, M. R.

    2013-05-01

    We numerically explore gyrotactic bioconvection in large spatially extended domains of finite depth using parameter values from available experiments with the unicellular alga Chlamydomonas nivalis. We numerically integrate the three-dimensional, time-dependent continuum model of Pedley [J. Fluid Mech.10.1017/S0022112088002393 195, 223 (1988)] using a high-order, parallel, spectral-element approach. We explore the long-time nonlinear patterns and dynamics found for layers with an aspect ratio of 10 over a range of Rayleigh numbers. Our results yield the pattern wavelength and pattern dynamics which we compare with available theory and experimental measurement. There is good agreement for the pattern wavelength at short times between numerics, experiment, and a linear stability analysis. At long times we find that the general sequence of patterns given by the nonlinear evolution of the governing equations correspond qualitatively to what has been described experimentally. However, at long times the patterns in numerics grow to larger wavelengths, in contrast to what is observed in experiment where the wavelength is found to decrease with time.

  6. Studies of extended planetary atmospheres

    NASA Astrophysics Data System (ADS)

    Hunten, Donald M.

    1988-08-01

    Spectroscopic observations of gases and plasmas in the Jupiter system, and related phenomena such as the recently-discovered sodium atmospheres of Mercury and the Moon were made. Cunningham's work on Jupiter spectroscopy is complete. The optical thickness of the ammonia cloud increases from about 3 in the morning to 6 at sunset. This effect seems to be due to the combination of internal heat flow and a convective region heated at the top, giving strong convection at night and none during the day. Near-simultaneous methane data are of poor quality, but are consistent with this picture. Schneider's work on the sodium environment of Io is also complete. The eclipse data extend to nearly 10 Io radii and nicely match the densities in the outer regions (to 100 Io radii) obtained from the intensity scattered in the D lines. Other data show very fast jets of sodium (up to 100 km/sec), frequently tilted out of the orbital plane. Researchers seem to be seeing neutralized ions, not from the torus itself but from atmospheric sodium ionized and then quickly neutralized. The data set on Mercurian sodium has been augmented, and supplemented by IR reflectance spectra.

  7. Extended attention span training system

    NASA Technical Reports Server (NTRS)

    Pope, Alan T.; Bogart, Edward H.

    1991-01-01

    Attention Deficit Disorder (ADD) is a behavioral disorder characterized by the inability to sustain attention long enough to perform activities such as schoolwork or organized play. Treatments for this disorder include medication and brainwave biofeedback training. Brainwave biofeedback training systems feed back information to the trainee showing him how well he is producing the brainwave pattern that indicates attention. The Extended Attention Span Training (EAST) system takes the concept a step further by making a video game more difficult as the player's brainwaves indicate that attention is waning. The trainee can succeed at the game only by maintaining an adequate level of attention. The EAST system is a modification of a biocybernetic system that is currently being used to assess the extent to which automated flight management systems maintain pilot engagement. This biocybernetic system is a product of a program aimed at developing methods to evaluate automated flight deck designs for compatibility with human capabilities. The EAST technology can make a contribution in the fields of medical neuropsychology and neurology, where the emphasis is on cautious, conservative treatment of youngsters with attention disorders.

  8. The Extended Mission Rover (EMR)

    NASA Technical Reports Server (NTRS)

    Shields, W.; Halecki, Anthony; Chung, Manh; Clarke, Ken; Frankle, Kevin; Kassemkhani, Fariba; Kuhlhoff, John; Lenzini, Josh; Lobdell, David; Morgan, Sam

    1992-01-01

    A key component in ensuring America's status as a leader in the global community is its active pursuit of space exploration. On the twentieth anniversary of Apollo 11, President George Bush challenged the nation to place a man on the moon permanently and to conduct human exploration of Mars in the 21st century. The students of the FAMU/FSU College of Engineering hope to make a significant contribution to this challenge, America's Space Exploration Initiative (SEI), with their participation in the NASA/USRA Advanced Design Program. The project selected by the 1991/1992 Aerospace Design group is the design of an Extended Mission Rover (EMR) for use on the lunar surface. This vehicle will serve as a mobile base to provide future astronauts with a 'shirt-sleeve' living and working environment. Some of the proposed missions are planetary surface exploration, construction and maintenance, hardware setup, and in situ resource experimentation. This vehicle will be put into use in the 2010-2030 time frame.

  9. Extended visual appearance texture features

    NASA Astrophysics Data System (ADS)

    Désage, Simon-Frédéric; Pitard, Gilles; Pillet, Maurice; Favrelière, Hugues; Maire, Jean-Luc; Frelin, Fabrice; Samper, Serge; Le Goïc, Gaëtan

    2015-03-01

    The research purpose is to improve surface characterization based on what is perceived by human eye and on the 2006 CIE report. This report defines four headings under which possible measures might be made: color, gloss, translucency and texture. It is therefore important to define parameters able to discriminate surfaces, in accordance with the perception of human eye. Our starting point in assessing a surface is the measurement of its reflectance (acquisition of ABRDF for visual rendering), i.e. evaluate a set of images from different angles of lighting rather than a single image. The research question is how calculate, from this enhanced information, some discriminating parameters. We propose to use an image processing approach of texture that reflects spatial variations of pixel for translating changes in color, material and relief. From a set of images from different angles of light, we compute associated Haralick features for constructing new (extended) features, called Bidimensional Haralick Functions (BHF), and exploit them for discriminating surfaces. We propose another framework in three parts such as color, material and relief.

  10. Earth Observing-1 Extended Mission

    USGS Publications Warehouse

    ,

    2005-01-01

    Since November 2000, the National Aeronautics and Space Administration (NASA) Earth Observing-1 (EO-1) mission has demonstrated the capabilities of a dozen spacecraft sensor and communication innovations. Onboard the EO-1 spacecraft are two land remote sensing instruments. The Advanced Land Imager (ALI) acquires data in spectral bands and at resolutions similar to Landsat. The Hyperion instrument, which is the first civilian spaceborne hyperspectral imager, acquires data in 220 10-nanometer bands covering the visible, near, and shortwave-infrared bands. The initial one-year technology demonstration phase of the mission included a detailed comparison of ALI with the Landsat Enhanced Thematic Mapper Plus (ETM+) instrument. Specifications for the Operational Land Imager (OLI), the planned successor to ETM+, were formulated in part from performance characteristics of ALI. Recognizing the remarkable performance of the satellite's instruments and the exceptional value of the data, the U.S. Geological Survey (USGS) and NASA agreed in December 2001 to share responsibility for operating EO-1. The extended mission continues, on a cost-reimbursable basis, as long as customer sales fully recover flight and ground operations costs. As of May 2005, more than 17,800 scenes from each instrument have been acquired, indexed, archived, and made available to the public.

  11. Earth Observing-1 Extended Mission

    USGS Publications Warehouse

    ,

    2003-01-01

    From its beginning in November 2000, the NASA Earth Observing-1 (EO-1) mission demonstrated the feasibility and performance of a dozen innovative sensor, spacecraft, and operational technologies. The 1-year mission tested a variety of technologies, some of which may be included on the planned 2007 Landsat Data Continuity Mission. Onboard the spacecraft are two land remote sensing instruments: the Advanced Land Imager (ALI), which acquires data in spectral bands and at resolutions similar to Landsat, and Hyperion, which acquires data in 220 10-nanometer-wide bands covering the visible, near-, and shortwave-infrared bands. Recognizing the remarkable performance of the satellite's instruments and the exceptional value of the data, the U.S. Geological Survey (USGS) and NASA agreed in December 2001 to share responsibility for operating EO-1 on a cost-reimbursable basis as long as customer sales are sufficient to recover flight and ground operations costs. The EO-1 extended mission operates within constraints imposed by its technology-pioneering origins, but it also provides unique and valuable capabilities. The spacecraft can acquire a target scene three times in a 16-day period. The ALI instrument has additional spectral coverage and greater radiometric dynamic range compared with the sensors on Landsat 7. Hyperion is the first civilian spaceborne hyperspectral imager. As of January 2003, more than 5,000 scenes had been acquired, indexed, and archived.

  12. An extended relativistic quantum oscillator for ? particles

    NASA Astrophysics Data System (ADS)

    Nedjadi, Y.; Ait-Tahar, S.; Barrett, R. C.

    1998-04-01

    We introduce the extended Duffin-Kemmer-Petiau (DKP) oscillator obtained by combining two relativistic quantum oscillator models. In a study analogous to Kukulin, Loyola and Moshinsky's work on extended Dirac oscillators, we investigate whether this extended version has oscillator shells controllably independent from the spin-orbit coupling. This extended DKP oscillator is found to be exactly solvable for natural parity states. We calculate and discuss both the natural- and unnatural-parity eigenspectra of its spin-1 representation.

  13. Extended Gibbs ensembles with flow

    SciTech Connect

    Ison, M. J.

    2007-11-15

    A recently proposed [Ph. Chomaz, F. Gulminelli, and O. Juillet, Ann. Phys. (Paris) 320, 135 (2005)] statistical treatment of finite unbound systems in the presence of collective motions is applied to a classical Lennard-Jones system, numerically simulated through molecular dynamics. In the ideal gas limit, the flow dynamics can be exactly recast into effective time-dependent Lagrange parameters acting on a standard Gibbs ensemble with an extra total energy conservation constraint. Using this same ansatz for the low-density freeze-out configurations of an interacting expanding system, we show that the presence of flow can have a sizable effect on the microstate distribution.

  14. Extended foil capacitor with radially spoked electrodes

    DOEpatents

    Foster, James C.

    1990-01-01

    An extended foil capacitor has a conductive disk electrically connected in oncrushing contact to the extended foil. A conductive paste is placed through spaces between radial spokes on the disk to electrically and mechanically connect the extended foil to the disk.

  15. 38 CFR 21.74 - Extended evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under 38 U.S.C. Chapter 31 Duration of Rehabilitation Programs § 21.74 Extended evaluation. (a) General. An extended evaluation may be... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Extended evaluation....

  16. Microscopic formulation of the interacting boson model for rotational nuclei

    SciTech Connect

    Nomura, Kosuke; Shimizu, Noritaka; Otsuka, Takaharu; Guo, Lu

    2011-04-15

    We propose a novel formulation of the interacting boson model (IBM) for rotational nuclei with axially symmetric, strong deformation. The intrinsic structure represented by the potential-energy surface (PES) of a given multinucleon system has a certain similarity to that of the corresponding multiboson system. Based on this feature, one can derive an appropriate boson Hamiltonian, as already reported. This prescription, however, has a major difficulty in the rotational spectra of strongly deformed nuclei: the bosonic moment of inertia is significantly smaller than the corresponding nucleonic one. We present that this difficulty originates in the difference between the rotational response of a nucleon system and that of the corresponding boson system, and could arise even if the PESs of the two systems were identical. We further suggest that the problem can be solved by implementing the L{center_dot}L term into the IBM Hamiltonian, with the coupling constant derived from the cranking approach of Skyrme mean-field models. The validity of the method is confirmed for rare-earth and actinoid nuclei, as their experimental rotational yrast bands are reproduced nicely.

  17. Niacin extended-release/simvastatin.

    PubMed

    Sanford, Mark; Curran, Monique P

    2008-01-01

    Niacin extended-release (ER)/simvastatin is a once-daily, fixed-dose combination of the HMG-CoA reductase inhibitor simvastatin and an ER formulation of niacin (a B-complex vitamin). In healthy volunteers who were given niacin ER/simvastatin 2000 mg/40 mg, niacin exposure was similar to that with niacin ER 2000 mg, while simvastatin exposure was increased compared to that with simvastatin 40 mg. In patients with elevated non-high-density lipoprotein cholesterol (non-HDL-C) but with low-density lipoprotein cholesterol (LDL-C) at or below the National Cholesterol Education Program (NCEP) goal after a > or = 2-week simvastatin 20 mg/day run-in period (SEACOAST I), 24 weeks of niacin ER/simvastatin 1000 mg/20 mg or 2000 mg/20 mg per day reduced median plasma non-HDL-C levels to a significantly greater extent than simvastatin 20 mg/day. In patients with elevated non-HDL-C and LDL-C at any level after a > or = 2-week simvastatin 40 mg/day run-in period (SEACOAST II), 24 weeks of niacin ER/simvastatin 1000 mg/40 mg or 2000 mg/40 mg per day was noninferior to simvastatin 80 mg/day in reducing median plasma non-HDL-C levels. Compared with simvastatin monotherapy, there was no significant difference in reduction in plasma LDL-C levels with niacin ER/simvastatin in SEACOAST I, and the noninferiority criterion for LDL-C was not met in SEACOAST II. However, plasma HDL-C levels increased more and triglyceride levels were lowered more than with simvastatin monotherapy (SEACOAST I and II). Niacin ER/simvastatin was generally well tolerated, with flushing being the most common adverse reaction.

  18. The Source of Saturn's Extended Neutral Cloud

    NASA Astrophysics Data System (ADS)

    Fleshman, B. L.; Delamere, P. A.; Bagenal, F.

    2010-12-01

    The Enceladus plumes are largely responsible for the water and its by-products found throughout Saturn's Enceladus plasma-neutral torus. Flybys of Enceladus by the Cassini spacecraft from 2005 to present have revealed a dynamic system, from which varying estimates have been made of the release rate of neutral H2O from Enceladus at 75-1600 kg/s. The rate of fresh ion pick-up near Enceladus has also been observed to vary between flybys. In Fleshman et al. (2010a), we showed that the magnitude of fresh ion pick-up on respective flybys requires a source (possibly in beams) of `hot' electrons at Enceladus. In this work, we build on our understanding of the local interaction by quantifying the degree to which neutrals produced as a by-product of charge exchange contribute to the Saturn's neutral cloud extending from 3 to 10 RS (see also Johnson et al., (2006)). We follow individual ion and neutral trajectories, while accounting for velocity-dependent cross sections. Our aim is to compare the neutral cloud resulting from charge exchange at Enceladus to that resulting from both (1) photodissociation and (2) electron impact dissociation throughout the Enceladus torus. The goal of the study, when compared with neutral cloud observations, is to shed light on which of these mechanisms dominates the neutral cloud morphology at Saturn.

  19. Building Action Principles for Extended MHD Models

    NASA Astrophysics Data System (ADS)

    Keramidas Charidakos, Ioannis; Lingam, Manasvi; Morrison, Philip; White, Ryan; Wurm, Alexander

    2014-10-01

    The general, non-dissipative, two-fluid model in plasma physics is Hamiltonian, but this property is sometimes lost in the process of deriving simplified two-fluid or one-fluid models from the two-fluid equations of motion. One way to ensure that the reduced models are Hamiltonian is to derive them from an action. We start with the general two-fluid action functional for an electron and an ion fluid interacting with an electromagnetic field, expressed in Lagrangian variables. We perform a change of variables and make various approximations (eg. quasineutrality and ordering of the fields) and small parameter expansions directly in the action. The resulting equations of motion are then mapped to the Eulerian fluid variables using a novel nonlocal Lagrange-Euler map. The correct Eulerian equations are obtained after we impose locality. Using this method and the proper approximations and expansions, we recover Lust's general two-fluid model, extended MHD, Hall MHD, and Electron MHD from a unified framework. The variational formulation allows us to use Noether's theorem to derive conserved quantities for each symmetry of the action. U.S. Dept. of Energy Contract # DE-FG05-80ET-53088, Western New England University Research Fund.

  20. Control of Multichaotic Systems Using the Extended OGY Method

    NASA Astrophysics Data System (ADS)

    Nobakhti, Ensieh; Khaki-Sedigh, Ali; Vasegh, Nastaran

    This paper considers the problem of controlling coupled chaotic maps. Coupled chaotic maps or multichaotic subsystems are complex dynamical systems that consist of several chaotic sub-systems with interactions. The OGY methodology is extended to deal with the control of such systems. It is shown that the decentralized control design scheme in which the individual controllers share no information is not generally able to control multichaotic systems. Simulation results are used to support the main conclusions of the paper.

  1. Fidelity study of superconductivity in extended Hubbard models

    DOE PAGES

    Plonka, N.; Jia, C. J.; Wang, Y.; ...

    2015-07-08

    The Hubbard model with local on-site repulsion is generally thought to possess a superconducting ground state for appropriate parameters, but the effects of more realistic long-range Coulomb interactions have not been studied extensively. We study the influence of these interactions on superconductivity by including nearest- and next-nearest-neighbor extended Hubbard interactions in addition to the usual on-site terms. Utilizing numerical exact diagonalization, we analyze the signatures of superconductivity in the ground states through the fidelity metric of quantum information theory. Finally, we find that nearest and next-nearest neighbor interactions have thresholds above which they destabilize superconductivity regardless of whether they aremore » attractive or repulsive, seemingly due to competing charge fluctuations.« less

  2. Fidelity study of superconductivity in extended Hubbard models

    SciTech Connect

    Plonka, N.; Jia, C. J.; Wang, Y.; Moritz, B.; Devereaux, T. P.

    2015-07-08

    The Hubbard model with local on-site repulsion is generally thought to possess a superconducting ground state for appropriate parameters, but the effects of more realistic long-range Coulomb interactions have not been studied extensively. We study the influence of these interactions on superconductivity by including nearest- and next-nearest-neighbor extended Hubbard interactions in addition to the usual on-site terms. Utilizing numerical exact diagonalization, we analyze the signatures of superconductivity in the ground states through the fidelity metric of quantum information theory. Finally, we find that nearest and next-nearest neighbor interactions have thresholds above which they destabilize superconductivity regardless of whether they are attractive or repulsive, seemingly due to competing charge fluctuations.

  3. Extended Hansen solubility approach: naphthalene in individual solvents.

    PubMed

    Martin, A; Wu, P L; Adjei, A; Beerbower, A; Prausnitz, J M

    1981-11-01

    A multiple regression method using Hansen partial solubility parameters, delta D, delta p, and delta H, was used to reproduce the solubilities of naphthalene in pure polar and nonpolar solvents and to predict its solubility in untested solvents. The method, called the extended Hansen approach, was compared with the extended Hildebrand solubility approach and the universal-functional-group-activity-coefficient (UNIFAC) method. The Hildebrand regular solution theory was also used to calculate naphthalene solubility. Naphthalene, an aromatic molecule having no side chains or functional groups, is "well-behaved', i.e., its solubility in active solvents known to interact with drug molecules is fairly regular. Because of its simplicity, naphthalene is a suitable solute with which to initiate the difficult study of solubility phenomena. The three methods tested (Hildebrand regular solution theory was introduced only for comparison of solubilities in regular solution) yielded similar results, reproducing naphthalene solubilities within approximately 30% of literature values. In some cases, however, the error was considerably greater. The UNIFAC calculation is superior in that it requires only the solute's heat of fusion, the melting point, and a knowledge of chemical structures of solute and solvent. The extended Hansen and extended Hildebrand methods need experimental solubility data on which to carry out regression analysis. The extended Hansen approach was the method of second choice because of its adaptability to solutes and solvents from various classes. Sample calculations are included to illustrate methods of predicting solubilities in untested solvents at various temperatures. The UNIFAC method was successful in this regard.

  4. Extended season for northern butterflies.

    PubMed

    Karlsson, Bengt

    2014-07-01

    Butterflies are like all insects in that they are temperature sensitive and a changing climate with higher temperatures might effect their phenology. Several studies have found support for earlier flight dates among the investigated species. A comparative study with data from a citizen science project, including 66 species of butterflies in Sweden, was undertaken, and the result confirms that most butterfly species now fly earlier during the season. This is especially evident for butterflies overwintering as adults or as pupae. However, the advancement in phenology is correlated with flight date, and some late season species show no advancement or have even postponed their flight dates and are now flying later in the season. The results also showed that latitude had a strong effect on the adult flight date, and most of the investigated species showed significantly later flights towards the north. Only some late flying species showed an opposite trend, flying earlier in the north. A majority of the investigated species in this study showed a general response to temperature and advanced their flight dates with warmer temperatures (on average they advanced their flight dates by 3.8 days/°C), although not all species showed this response. In essence, a climate with earlier springs and longer growing seasons seems not to change the appearance patterns in a one-way direction. We now see butterflies on the wings both earlier and later in the season and some consequences of these patterns are discussed. So far, studies have concentrated mostly on early season butterfly-plant interactions but also late season studies are needed for a better understanding of long-term population consequences.

  5. Extended season for northern butterflies

    NASA Astrophysics Data System (ADS)

    Karlsson, Bengt

    2014-07-01

    Butterflies are like all insects in that they are temperature sensitive and a changing climate with higher temperatures might effect their phenology. Several studies have found support for earlier flight dates among the investigated species. A comparative study with data from a citizen science project, including 66 species of butterflies in Sweden, was undertaken, and the result confirms that most butterfly species now fly earlier during the season. This is especially evident for butterflies overwintering as adults or as pupae. However, the advancement in phenology is correlated with flight date, and some late season species show no advancement or have even postponed their flight dates and are now flying later in the season. The results also showed that latitude had a strong effect on the adult flight date, and most of the investigated species showed significantly later flights towards the north. Only some late flying species showed an opposite trend, flying earlier in the north. A majority of the investigated species in this study showed a general response to temperature and advanced their flight dates with warmer temperatures (on average they advanced their flight dates by 3.8 days/°C), although not all species showed this response. In essence, a climate with earlier springs and longer growing seasons seems not to change the appearance patterns in a one-way direction. We now see butterflies on the wings both earlier and later in the season and some consequences of these patterns are discussed. So far, studies have concentrated mostly on early season butterfly-plant interactions but also late season studies are needed for a better understanding of long-term population consequences.

  6. Extended season for northern butterflies

    NASA Astrophysics Data System (ADS)

    Karlsson, Bengt

    2013-03-01

    Butterflies are like all insects in that they are temperature sensitive and a changing climate with higher temperatures might effect their phenology. Several studies have found support for earlier flight dates among the investigated species. A comparative study with data from a citizen science project, including 66 species of butterflies in Sweden, was undertaken, and the result confirms that most butterfly species now fly earlier during the season. This is especially evident for butterflies overwintering as adults or as pupae. However, the advancement in phenology is correlated with flight date, and some late season species show no advancement or have even postponed their flight dates and are now flying later in the season. The results also showed that latitude had a strong effect on the adult flight date, and most of the investigated species showed significantly later flights towards the north. Only some late flying species showed an opposite trend, flying earlier in the north. A majority of the investigated species in this study showed a general response to temperature and advanced their flight dates with warmer temperatures (on average they advanced their flight dates by 3.8 days/°C), although not all species showed this response. In essence, a climate with earlier springs and longer growing seasons seems not to change the appearance patterns in a one-way direction. We now see butterflies on the wings both earlier and later in the season and some consequences of these patterns are discussed. So far, studies have concentrated mostly on early season butterfly-plant interactions but also late season studies are needed for a better understanding of long-term population consequences.

  7. Standardizing Interaction Design Education

    ERIC Educational Resources Information Center

    Thomassen, Aukje; Ozcan, Oguzhan

    2010-01-01

    The objective of this paper is to which extend the didactic format of studio-based group-work is applicable for creating a common-ground for Interaction Design Education in European Perspective. The current debate on design education shows us a landscape of different initiatives. So far difficulties have arisen in the area of accreditation and…

  8. Extended optical-emission-line gas in powerful radio galaxies

    SciTech Connect

    Baum, S.A.

    1987-01-01

    Results of a search for extended optical-emission-line gas in 43 powerful radio galaxies are presented. Spatially extended optical-emission-line gas is common in these galaxies. The extent and luminosity of the emission-line gas in powerful radio galaxies is an order of magnitude greater than in normal elliptical galaxies of similar optical magnitudes. The total emission-line luminosity is roughly half of the radio luminosity, and the radio luminosity correlates with the narrow-line luminosity over four decades. The near-nuclear emission-line gas is often distributed in a smooth, roughly elliptical feature, centered on and symmetric about the nucleus. The distribution of axial ratios found in these small emission-line nebulae (ELN) is inconsistent with them being disks seen from different orientations. The minor axes of the small regions of emission-line gas show only a weak tendency to align with the position angle of the extended radio source and the major axis of the stellar isophotes. The very extended emission line gas (d{sub neb} > 10 kpc) is filamentary and is found preferentially within the regions occupied by the radio source. The small (d{sub radio} < 100 kpc) radio sources with very extended ELN show evidence of interacting with their gas-rich environments; the large (d{sub radio} > 100 kpc) radio sources with very extended ELN show no signs that they have been disturbed by their surrounding media. Lower limits to the density of the emission line gas at distances of 10 kpc from the galaxy nucleus are {approximately}0.1 cm{sup {minus}3} and upper limits to the total mass in emission line gas are {approximately}10{sup 9} M {circle dot}. The optical nuclear continuum is strongly correlated with the narrow emission line luminosity and is sufficient to photoionize the ELN.

  9. Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span.

    PubMed

    Kumar, Sandeep; Dietrich, Nicholas; Kornfeld, Kerry

    2016-02-01

    Animal aging is characterized by progressive, degenerative changes in many organ systems. Because age-related degeneration is a major contributor to disability and death in humans, treatments that delay age-related degeneration are desirable. However, no drugs that delay normal human aging are currently available. To identify drugs that delay age-related degeneration, we used the powerful Caenorhabditis elegans model system to screen for FDA-approved drugs that can extend the adult lifespan of worms. Here we show that captopril extended mean lifespan. Captopril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure in humans. To explore the mechanism of captopril, we analyzed the acn-1 gene that encodes the C. elegans homolog of ACE. Reducing the activity of acn-1 extended the mean life span. Furthermore, reducing the activity of acn-1 delayed age-related degenerative changes and increased stress resistance, indicating that acn-1 influences aging. Captopril could not further extend the lifespan of animals with reduced acn-1, suggesting they function in the same pathway; we propose that captopril inhibits acn-1 to extend lifespan. To define the relationship with previously characterized longevity pathways, we analyzed mutant animals. The lifespan extension caused by reducing the activity of acn-1 was additive with caloric restriction and mitochondrial insufficiency, and did not require sir-2.1, hsf-1 or rict-1, suggesting that acn-1 functions by a distinct mechanism. The interactions with the insulin/IGF-1 pathway were complex, since the lifespan extensions caused by captopril and reducing acn-1 activity were additive with daf-2 and age-1 but required daf-16. Captopril treatment and reducing acn-1 activity caused similar effects in a wide range of genetic backgrounds, consistent with the model that they act by the same mechanism. These results identify a new drug and a new gene that can extend the lifespan of worms and suggest new

  10. Extended Neural Metastability in an Embodied Model of Sensorimotor Coupling

    PubMed Central

    Aguilera, Miguel; Bedia, Manuel G.; Barandiaran, Xabier E.

    2016-01-01

    The hypothesis that brain organization is based on mechanisms of metastable synchronization in neural assemblies has been popularized during the last decades of neuroscientific research. Nevertheless, the role of body and environment for understanding the functioning of metastable assemblies is frequently dismissed. The main goal of this paper is to investigate the contribution of sensorimotor coupling to neural and behavioral metastability using a minimal computational model of plastic neural ensembles embedded in a robotic agent in a behavioral preference task. Our hypothesis is that, under some conditions, the metastability of the system is not restricted to the brain but extends to the system composed by the interaction of brain, body and environment. We test this idea, comparing an agent in continuous interaction with its environment in a task demanding behavioral flexibility with an equivalent model from the point of view of “internalist neuroscience.” A statistical characterization of our model and tools from information theory allow us to show how (1) the bidirectional coupling between agent and environment brings the system closer to a regime of criticality and triggers the emergence of additional metastable states which are not found in the brain in isolation but extended to the whole system of sensorimotor interaction, (2) the synaptic plasticity of the agent is fundamental to sustain open structures in the neural controller of the agent flexibly engaging and disengaging different behavioral patterns that sustain sensorimotor metastable states, and (3) these extended metastable states emerge when the agent generates an asymmetrical circular loop of causal interaction with its environment, in which the agent responds to variability of the environment at fast timescales while acting over the environment at slow timescales, suggesting the constitution of the agent as an autonomous entity actively modulating its sensorimotor coupling with the world. We

  11. Extended Neural Metastability in an Embodied Model of Sensorimotor Coupling.

    PubMed

    Aguilera, Miguel; Bedia, Manuel G; Barandiaran, Xabier E

    2016-01-01

    The hypothesis that brain organization is based on mechanisms of metastable synchronization in neural assemblies has been popularized during the last decades of neuroscientific research. Nevertheless, the role of body and environment for understanding the functioning of metastable assemblies is frequently dismissed. The main goal of this paper is to investigate the contribution of sensorimotor coupling to neural and behavioral metastability using a minimal computational model of plastic neural ensembles embedded in a robotic agent in a behavioral preference task. Our hypothesis is that, under some conditions, the metastability of the system is not restricted to the brain but extends to the system composed by the interaction of brain, body and environment. We test this idea, comparing an agent in continuous interaction with its environment in a task demanding behavioral flexibility with an equivalent model from the point of view of "internalist neuroscience." A statistical characterization of our model and tools from information theory allow us to show how (1) the bidirectional coupling between agent and environment brings the system closer to a regime of criticality and triggers the emergence of additional metastable states which are not found in the brain in isolation but extended to the whole system of sensorimotor interaction, (2) the synaptic plasticity of the agent is fundamental to sustain open structures in the neural controller of the agent flexibly engaging and disengaging different behavioral patterns that sustain sensorimotor metastable states, and (3) these extended metastable states emerge when the agent generates an asymmetrical circular loop of causal interaction with its environment, in which the agent responds to variability of the environment at fast timescales while acting over the environment at slow timescales, suggesting the constitution of the agent as an autonomous entity actively modulating its sensorimotor coupling with the world. We

  12. 42 CFR 488.310 - Extended survey.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Extended survey. 488.310 Section 488.310 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Long-Term Care Facilities § 488.310 Extended survey. (a) Purpose of survey. The purpose of an...

  13. 42 CFR 488.720 - Extended surveys.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Extended surveys. 488.720 Section 488.720 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Home Health Agencies § 488.720 Extended surveys. (a) Purpose of survey. The purpose of an...

  14. 42 CFR 488.310 - Extended survey.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 5 2014-10-01 2014-10-01 false Extended survey. 488.310 Section 488.310 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Long-Term Care Facilities § 488.310 Extended survey. (a) Purpose of survey. The purpose of an...

  15. 42 CFR 488.310 - Extended survey.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Extended survey. 488.310 Section 488.310 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Long-Term Care Facilities § 488.310 Extended survey. (a) Purpose of survey. The purpose of an...

  16. 42 CFR 488.310 - Extended survey.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 5 2011-10-01 2011-10-01 false Extended survey. 488.310 Section 488.310 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Long-Term Care Facilities § 488.310 Extended survey. (a) Purpose of survey. The purpose of an...

  17. 42 CFR 488.310 - Extended survey.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 5 2012-10-01 2012-10-01 false Extended survey. 488.310 Section 488.310 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Long-Term Care Facilities § 488.310 Extended survey. (a) Purpose of survey. The purpose of an...

  18. 42 CFR 488.720 - Extended surveys.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 5 2013-10-01 2013-10-01 false Extended surveys. 488.720 Section 488.720 Public...) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES Survey and Certification of Home Health Agencies § 488.720 Extended surveys. (a) Purpose of survey. The purpose of an...

  19. Evaluation of Kentucky's Extended School Services Program.

    ERIC Educational Resources Information Center

    Meehan, Merrill L.; Cowley, Kimberly S.; Schumacher, Debbie; Hauser, Brenda

    The Extended School Services (ESS) program was established in 1990 as part of the Kentucky Education Reform Act. The program extends the school day, week, or year for students at risk of academic failure, providing them with additional instructional time to help them meet academic goals. An evaluation of ESS in 2001 utilized statewide surveys and…

  20. Big Gods: Extended prosociality or group binding?

    PubMed

    Galen, Luke W

    2016-01-01

    Big Gods are described as having a "prosocial" effect. However, this conflates parochialism (group cohesion) with cooperation extended to strangers or out-group members. An examination of the cited experimental studies indicates that religion is actually associated with increased within-group parochialism, rather than extended or universal prosociality, and that the same general mechanisms underlie both religious and secular effects.

  1. Extended, Embodied Cognition and Second Language Acquisition

    ERIC Educational Resources Information Center

    Atkinson, Dwight

    2010-01-01

    A "cognitivist" approach to cognition has traditionally dominated second language acquisition (SLA) studies. In this article, I examine two alternative approaches--"extended cognition" and "embodied cognition"--for how they might help us conceptualize SLA. More specifically, I present: (i) summaries of extended and embodied cognition, followed by…

  2. Supersymmetric descendants of self-adjointly extended quantum mechanical Hamiltonians

    NASA Astrophysics Data System (ADS)

    Al-Hashimi, M. H.; Salman, M.; Shalaby, A.; Wiese, U.-J.

    2013-10-01

    We consider the descendants of self-adjointly extended Hamiltonians in supersymmetric quantum mechanics on a half-line, on an interval, and on a punctured line or interval. While there is a 4-parameter family of self-adjointly extended Hamiltonians on a punctured line, only a 3-parameter sub-family has supersymmetric descendants that are themselves self-adjoint. We also address the self-adjointness of an operator related to the supercharge, and point out that only a sub-class of its most general self-adjoint extensions is physical. Besides a general characterization of self-adjoint extensions and their supersymmetric descendants, we explicitly consider concrete examples, including a particle in a box with general boundary conditions, with and without an additional point interaction. We also discuss bulk-boundary resonances and their manifestation in the supersymmetric descendant.

  3. Shock wave refraction enhancing conditions on an extended interface

    SciTech Connect

    Markhotok, A.; Popovic, S.

    2013-04-15

    We determined the law of shock wave refraction for a class of extended interfaces with continuously variable gradients. When the interface is extended or when the gas parameters vary fast enough, the interface cannot be considered as sharp or smooth and the existing calculation methods cannot be applied. The expressions we derived are general enough to cover all three types of the interface and are valid for any law of continuously varying parameters. We apply the equations to the case of exponentially increasing temperature on the boundary and compare the results for all three types of interfaces. We have demonstrated that the type of interface can increase or inhibit the shock wave refraction. Our findings can be helpful in understanding the results obtained in energy deposition experiments as well as for controlling the shock-plasma interaction in other settings.

  4. Agent-Enriched Data Mining Using an Extendable Framework

    NASA Astrophysics Data System (ADS)

    Albashiri, Kamal Ali; Coenen, Frans

    This paper commences with a discussion of the advantages that Multi-Agent Systems (MAS) can bring to the domain of Knowledge Discovery in Data (KDD), and presents a rational for Agent-Enriched Data Mining (AEDM). A particular challenge of any generic, general purpose, AEDM system is the extensive scope of KDD. To address this challenge the authors suggest that any truly generic AEDM must be readily extendable and propose EMADS, The Extendable Multi-Agent Data mining System. A complete overview of the architecture and agent interaction models of EMADS is presented. The system’s operation is described and illustrated in terms of two KDD scenarios: meta association rule mining and classifier generation. In conclusion the authors suggest that EMADS provides a sound foundation for both KDD research and application based AEDM.

  5. Spin slush in an extended spin ice model

    PubMed Central

    Rau, Jeffrey G.; Gingras, Michel J. P.

    2016-01-01

    We present a new classical spin liquid on the pyrochlore lattice by extending spin ice with further neighbour interactions. We find that this disorder-free spin model exhibits a form of dynamical heterogeneity with extremely slow relaxation for some spins, while others fluctuate quickly down to zero temperature. We thus call this state spin slush, in analogy to the heterogeneous mixture of solid and liquid water. This behaviour is driven by the structure of the ground-state manifold which extends the celebrated two-in/two-out ice states to include branching structures built from three-in/one-out, three-out/one-in and all-in/all-out tetrahedra defects. Distinctive liquid-like patterns in the magnetic correlations serve as a signature of this intermediate range order. Possible applications to materials as well the effects of quantum tunnelling are discussed. PMID:27470199

  6. Supersymmetric descendants of self-adjointly extended quantum mechanical Hamiltonians

    SciTech Connect

    Al-Hashimi, M.H.; Salman, M.; Shalaby, A.; Wiese, U.-J.

    2013-10-15

    We consider the descendants of self-adjointly extended Hamiltonians in supersymmetric quantum mechanics on a half-line, on an interval, and on a punctured line or interval. While there is a 4-parameter family of self-adjointly extended Hamiltonians on a punctured line, only a 3-parameter sub-family has supersymmetric descendants that are themselves self-adjoint. We also address the self-adjointness of an operator related to the supercharge, and point out that only a sub-class of its most general self-adjoint extensions is physical. Besides a general characterization of self-adjoint extensions and their supersymmetric descendants, we explicitly consider concrete examples, including a particle in a box with general boundary conditions, with and without an additional point interaction. We also discuss bulk-boundary resonances and their manifestation in the supersymmetric descendant. -- Highlights: •Self-adjoint extension theory and contact interactions. •Application of self-adjoint extensions to supersymmetry. •Contact interactions in finite volume with Robin boundary condition.

  7. Novel Functional Extended Solids at Extreme Conditions

    DTIC Science & Technology

    2013-02-01

    characterization of static and dynamic properties of energetic materials. A. Functional Extended Solids: Super Oxidizing Candidates A1. Novel 2D and 3D...fundamental rules in high-pressure chemistry such as pressure-induced electron delocalization, from sp3d hybridized Xe atoms in linear XeF2, to sp3d2 in 2D ... graphite -like 2D extended phase (Pnnm-2, middle) at 52 GPa, and metallic fluorite-like 3D extended phase (Fmmm, right) at 70 GPa. 4 from that of C

  8. Life extending control: A concept paper

    NASA Technical Reports Server (NTRS)

    Lorenzo, Carl F.; Merrill, Walter C.

    1991-01-01

    The concept of Life Extending Control is defined. Life is defined in terms of mechanical fatigue life. A brief description is given of the current approach to life prediction using a local, cyclic, stress-strain approach for a critical system component. An alternative approach to life prediction based on a continuous functional relationship to component performance is proposed.Base on cyclic life prediction an approach to Life Extending Control, called the Life Management Approach is proposed. A second approach, also based on cyclic life prediction, called the Implicit Approach, is presented. Assuming the existence of the alternative functional life prediction approach, two additional concepts for Life Extending Control are presented.

  9. Apparatus and methods for a human extender

    DOEpatents

    Jansen, John F.

    2001-01-01

    A human extender controller for interface between a human operator and a physical object through a physical plant. The human extender controller uses an inner-feedback loop to increase the equivalent damping of the operating system to stabilize the system when it contacts with the environment and reduces the impact of the environment variation by utilizing a high feedback gain, determined by a root locus sketch. Because the stability of the human extender controller of the present invention is greatly enhanced over that of the prior art, the present invention is able to achieve a force reflection ratio 500 to 1 and capable of handling loads above the two (2) ton range.

  10. Extended core for motor/generator

    DOEpatents

    Shoykhet, Boris A.

    2005-05-10

    An extended stator core in a motor/generator can be utilized to mitigate losses in end regions of the core and a frame of the motor/generator. To mitigate the losses, the stator core can be extended to a length substantially equivalent to or greater than a length of a magnetically active portion in the rotor. Alternatively, a conventional length stator core can be utilized with a shortened magnetically active portion to mitigate losses in the motor/generator. To mitigate the losses in the core caused by stator winding, the core can be extended to a length substantially equivalent or greater than a length of stator winding.

  11. Extended core for motor/generator

    DOEpatents

    Shoykhet, Boris A.

    2006-08-22

    An extended stator core in a motor/generator can be utilized to mitigate losses in end regions of the core and a frame of the motor/generator. To mitigate the losses, the stator core can be extended to a length substantially equivalent to or greater than a length of a magnetically active portion in the rotor. Alternatively, a conventional length stator core can be utilized with a shortened magnetically active portion to mitigate losses in the motor/generator. To mitigate the losses in the core caused by stator winding, the core can be extended to a length substantially equivalent or greater than a length of stator winding.

  12. Generalized Laplace Transforms and Extended Heaviside Calculus

    ERIC Educational Resources Information Center

    Deakin, Michael A. B.

    2008-01-01

    An extended Heaviside calculus proposed by Peraire in a recent paper is similar to a generalization of the Laplace transform proposed by the present author. This similarity will be illustrated by analysis of an example supplied by Peraire.

  13. Extended Adjuvant Therapy for Breast Cancer

    Cancer.gov

    An NCI Cancer Currents blog on findings from a recent clinical trial which showed that extending adjuvant therapy with an aromatase inhibitor can have important benefits for some women with early-stage cancer.

  14. 70 Years Making the World Safer: Extended

    SciTech Connect

    2017-01-01

    Extended version with narration. This video shows our roles in making the world safer — working to end World War II, providing stable isotopes for research, providing unique precision manufacturing capabilities, and meeting nonproliferation and global security missions.

  15. Extending applicability of terahertz spectroscopy for biosensing

    NASA Astrophysics Data System (ADS)

    Parthasarathy, Ramakrishnan

    Terahertz (THz) vibrational resonance spectroscopy has recently emerged as a promising technique for fingerprinting biological molecules. Absorption spectra in this frequency range (0.1-10 THz) reflect molecular internal vibrations involving the weakest hydrogen bonds and/or non-bonded interactions, which are species specific. Of prime importance is improving detection sensitivity of molecules with low absorption characteristics in the THz gap. Also of importance is the characterization of biological molecules in the THz gap (10-25 cm-1) by physical parameters (refractive index and absorption coefficient) rather than sample dependent parameters (transmission, reflection) and extending spectroscopy to the low THz range where remote sensing is most viable. To address the sensitivity issue, it is shown that periodic arrays of rectangular slots with subwavelength width provide for local electromagnetic field enhancements due to edge effects in the low frequency range of interest, 10-25 cm-1 (300-750 GHz). Periodic structures of Au, doped Si and InSb were studied. InSb is confirmed to offer the highest results with the local power enhancements on the order of 1100 at frequency 14 cm -1. InSb and Si have large skin depths in the frequency range of interest and so the analysis of their structures was done through the Fourier expansion method of field diffracted from gratings. Au however has small skin depths at these frequencies compared to the thickness. Surface impedance boundary conditions were employed to model the Au structure, for which the Fourier expansion method was unsuitable owing to the huge magnitude of Au permittivity. The applications possibly include development of novel bio-sensors, with the strongly enhanced local electromagnetic fields leading to increased detection sensitivity, and monitoring biophysical processes such as DNA denaturation. Transmission and reflection data from parallel, independent experiments are utilized in the Interference

  16. EMADS: An Extendible Multi-Agent Data Miner

    NASA Astrophysics Data System (ADS)

    Albashiri, Kamal Ali; Coenen, Frans; Leng, Paul

    In this paper we describe EMADS, an Extendible Multi-Agent Data mining System. The EMADS vision is that of a community of data mining agents, contributed by many individuals, interacting under decentralised control to address data mining requests. EMADS is seen both as an end user application and a research tool. This paper details the EMADS vision, the associated conceptual framework and the current implementation. Although EMADS may be applied to many data mining tasks; the study described here, for the sake of brevity, concentrates on agent based data classification. A full description of EMADS is presented.

  17. The EMADS Extendible Multi-Agent Data Mining Framework

    NASA Astrophysics Data System (ADS)

    Albashiri, Kamal Ali; Coenen, Frans

    In this chapter we describe EMADS, an Extendible Multi-Agent Data mining System. The EMADS vision is that of a community of data mining agents, contributed by many individuals and interacting under decentralized control, to address data mining requests. EMADS is seen both as an end user platform and a research tool. This chapter details the EMADS vision, the associated conceptual framework and the current implementation. Although EMADS may be applied to many data mining tasks; the study described here, for the sake of brevity, concentrates on agent based Association Rule Mining and agent based classification. A full description of EMADS is presented.

  18. New approach to flavor symmetry and an extended naturalness principle

    NASA Astrophysics Data System (ADS)

    Barr, S. M.

    2010-09-01

    A class of nonsupersymmetric extensions of the standard model is proposed in which there is a multiplicity of light scalar doublets in a multiplet of a nonabelian family group with the standard model Higgs doublet. Anthropic tuning makes the latter light, and consequently the other scalar doublets remain light because of the family symmetry. The family symmetry greatly constrains the pattern of flavor-changing neutral-current interactions (FCNC) and p decay operators coming from scalar-exchange. Such models show that useful constraints on model-building can come from an extended naturalness principle when the electroweak scale is anthropically tuned.

  19. Extending the Transdiagnostic Model of Attachment and Psychopathology

    PubMed Central

    Ein-Dor, Tsachi; Viglin, Dina; Doron, Guy

    2016-01-01

    Research has suggested that high levels of attachment insecurities that are formed through interactions with significant others are associated with a general vulnerability to mental disorders. In the present paper, we extend Ein-Dor and Doron’s (2015) transdiagnostic model linking attachment orientations with internalizing and externalizing symptoms, to include thought disorder spectrum symptoms. Specifically, we speculate on the processes that mediate the linkage between attachment insecurities and psychosis and obsessive compulsive disorder (OCD) symptoms, and indicate the different contexts that might set a trajectory of one individual to one set of symptoms while another individual to a different set of symptoms. PMID:27064251

  20. Moyer model approximations for point and extended beam losses

    NASA Astrophysics Data System (ADS)

    McCaslin, Joseph B.; Swanson, William P.; Thomas, Ralph H.

    1987-05-01

    The use of the empirical Moyer model for the determination of transverse neutron shielding for high-energy proton accelerators is described and discussed. It is shown that an important advantage of the Moyer Model is the physical insight it offers towards understanding the complex interactions that comprise the shielding processes. Calculations for pointlike and extended uniform beam loss distributions are discussed and their relationship to practical shielding conditions developed. The calculations required by the model are readily performed on small programmable calculators and thus are widely accessible. Program listings for practical calculations using a Hewlett-Packard HP-97 calculator are available on request.

  1. eXtended MetaData Registry

    SciTech Connect

    2006-10-25

    The purpose of the eXtended MetaData Registry (XMDR) prototype is to demonstrate the feasibility and utility of constructing an extended metadata registry, i.e., one which encompasses richer classification support, facilities for including terminologies, and better support for formal specification of semantics. The prototype registry will also serve as a reference implementation for the revised versions of ISO 11179, Parts 2 and 3 to help guide production implementations.

  2. Extended-release methylphenidate (Ritalin LA).

    PubMed

    Lyseng-Williamson, Katherine A; Keating, Gillian M

    2002-01-01

    An extended-release formulation of methylphenidate (Ritalin LA), a CNS stimulant that inhibits dopamine and noradrenaline (norepinephrine) reuptake into presynaptic neurons, has been developed for use in patients with attention deficit/hyperactivity disorder (ADHD). In children with ADHD and healthy male adults, extended-release methylphenidate 20mg was rapidly absorbed and demonstrated two distinct peak plasma concentrations approximately 4 hours apart. The absorption pharmacokinetics of extended-release methylphenidate 20mg, which closely mimics those of immediate-release methylphenidate 10mg given in two doses 4 hours apart, permits once-daily administration. In a 2-week randomised, double-blind, placebo-controlled trial in 134 evaluable children aged 6 to 12 years with ADHD, symptoms improved to a significantly greater extent with extended-release methylphenidate 10 to 40mg once daily than with placebo. Extended-release methylphenidate improved both inattention and hyperactivity symptoms and was effective in children with combined- (inattentive and hyperactive/impulsive) type or predominantly inattentive-type ADHD. In clinical trials, the safety and tolerability profiles of extended-release methylphenidate were consistent with that of the immediate-release formulation.

  3. NLOphoric Carbazole-Containing Push-Pull Extended Styryl Chromophores: Study of Photophysical Properties by Solvatochromic and DFT Method.

    PubMed

    Telore, Rahul D; Sekar, Nagaiyan

    2016-07-01

    Carbazole based extended Donor-π-Acceptor styryl dyes with intramolecular charge transfer characteristics were examined for their linear and nonlinear optical properties using solvatochromism, shifts in emission and density functional theory computations. All the extended styryls demonstrated positive solvatochromism. The extended styryl dyes showed largely improved photophysical properties and large Stokes shifts. The donor-acceptor interactions of the extended styryls were investigated by using generalized Mulliken-Hush method. Oscillator strengths and transition state dipole moments have been studied to understand charge transfer within the molecules. The nonlinear optical properties of the extended styryl were investigated by solvatochromic and density functional theory method.

  4. The Average Field Approximation for Almost Bosonic Extended Anyons

    NASA Astrophysics Data System (ADS)

    Lundholm, Douglas; Rougerie, Nicolas

    2015-12-01

    Anyons are 2D or 1D quantum particles with intermediate statistics, interpolating between bosons and fermions. We study the ground state of a large number N of 2D anyons, in a scaling limit where the statistics parameter α is proportional to N ^{-1} when N→ ∞ . This means that the statistics is seen as a "perturbation from the bosonic end". We model this situation in the magnetic gauge picture by bosons interacting through long-range magnetic potentials. We assume that these effective statistical gauge potentials are generated by magnetic charges carried by each particle, smeared over discs of radius R (extended anyons). Our method allows to take R→ 0 not too fast at the same time as N→ ∞ . In this limit we rigorously justify the so-called "average field approximation": the particles behave like independent, identically distributed bosons interacting via a self-consistent magnetic field.

  5. Movement of elongation factor G between compact and extended conformations.

    PubMed

    Salsi, Enea; Farah, Elie; Netter, Zoe; Dann, Jillian; Ermolenko, Dmitri N

    2015-01-30

    Previous structural studies suggested that ribosomal translocation is accompanied by large interdomain rearrangements of elongation factor G (EF-G). Here, we follow the movement of domain IV of EF-G relative to domain II of EF-G using ensemble and single-molecule Förster resonance energy transfer. Our results indicate that ribosome-free EF-G predominantly adopts a compact conformation that can also, albeit infrequently, transition into a more extended conformation in which domain IV moves away from domain II. By contrast, ribosome-bound EF-G predominantly adopts an extended conformation regardless of whether it is interacting with pretranslocation ribosomes or with posttranslocation ribosomes. Our data suggest that ribosome-bound EF-G may also occasionally sample at least one more compact conformation. GTP hydrolysis catalyzed by EF-G does not affect the relative stability of the observed conformations in ribosome-free and ribosome-bound EF-G. Our data support a model suggesting that, upon binding to a pretranslocation ribosome, EF-G moves from a compact to a more extended conformation. This transition is not coupled to but likely precedes both GTP hydrolysis and mRNA/tRNA translocation.

  6. Movement of Elongation Factor G between Compact and Extended Conformations

    PubMed Central

    Salsi, Enea; Farah, Elie; Netter, Zoe; Dann, Jillian; Ermolenko, Dmitri N.

    2014-01-01

    Previous structural studies suggested that ribosomal translocation is accompanied by large interdomain rearrangements of elongation factor G (EF-G). Here, we follow the movement of domain IV of EF-G relative to domain II of EF-G using ensemble and single-molecule Förster resonance energy transfer (smFRET). Our results indicate that ribosome-free EF-G predominantly adopts a compact conformation that can also, albeit infrequently, transition into a more extended conformation in which domain IV moves away from domain II. By contrast, ribosome-bound EF-G predominantly adopts an extended conformation regardless of whether it is interacting with pre- or posttranslocation ribosomes. Our data suggest that ribosome-bound EF-G may also occasionally sample at least one more compact conformation. GTP hydrolysis catalyzed by EF-G does not affect the relative stability of the observed conformations in ribosome-free and ribosome-bound EF-G. Our data support a model suggesting that, upon binding to a pretranslocation ribosome, EF-G moves from a compact to a more extended conformation. This transition is not coupled to, but likely precedes both GTP hydrolysis and mRNA/tRNA translocation. PMID:25463439

  7. Extended range radiation dose-rate monitor

    DOEpatents

    Valentine, Kenneth H.

    1988-01-01

    An extended range dose-rate monitor is provided which utilizes the pulse pileup phenomenon that occurs in conventional counting systems to alter the dynamic response of the system to extend the dose-rate counting range. The current pulses from a solid-state detector generated by radiation events are amplified and shaped prior to applying the pulses to the input of a comparator. The comparator generates one logic pulse for each input pulse which exceeds the comparator reference threshold. These pulses are integrated and applied to a meter calibrated to indicate the measured dose-rate in response to the integrator output. A portion of the output signal from the integrator is fed back to vary the comparator reference threshold in proportion to the output count rate to extend the sensitive dynamic detection range by delaying the asymptotic approach of the integrator output toward full scale as measured by the meter.

  8. Extending Double Optical Gating to the Midinfrared

    NASA Astrophysics Data System (ADS)

    Gorman, Timothy; Camper, Antoine; Agostini, Pierre; Dimauro, Louis

    2015-05-01

    In the past decade there has been great interest in creating broadband isolated attosecond pulses (IAPs). Primarily these IAPs have been generated using Ti:Sapphire 800nm short pulses, namely through spatiotemporal gating with the attosecond lighthouse technique, amplitude gating, polarization gating, and double optical gating (DOG). Here we present theoretical calculations and experimental investigations into extending DOG to using a 2 μm driving wavelength, the benefits of which include extended harmonic cutoff and longer input driving pulse durations. It is proposed that broadband IAPs with cutoffs extending up to 250 eV can be generated in Argon by using >30 fs pulses from the passively-CEP stabilized 2 μm idler out of an optical parametric amplifier combined with a collinear DOG experimental setup.

  9. Extended Kalman filtering of point process observation.

    PubMed

    Salimpour, Yousef; Soltanian-Zadeh, Hamid; Abolhassani, Mohammad D

    2010-01-01

    A temporal point process is a stochastic time series of binary events that occurs in continuous time. In computational neuroscience, the point process is used to model neuronal spiking activity; however, estimating the model parameters from spike train is a challenging problem. The state space point process filtering theory is a new technique for the estimation of the states and parameters. In order to use the stochastic filtering theory for the states of neuronal system with the Gaussian assumption, we apply the extended Kalman filter. In this regard, the extended Kalman filtering equations are derived for the point process observation. We illustrate the new filtering algorithm by estimating the effect of visual stimulus on the spiking activity of object selective neurons from the inferior temporal cortex of macaque monkey. Based on the goodness-offit assessment, the extended Kalman filter provides more accurate state estimate than the conventional methods.

  10. Remarkable connections between extended magnetohydrodynamics models

    SciTech Connect

    Lingam, M. Morrison, P. J. Miloshevich, G.

    2015-07-15

    Through the use of suitable variable transformations, the commonality of all extended magnetohydrodynamics (MHD) models is established. Remarkable correspondences between the Poisson brackets of inertialess Hall MHD and inertial MHD (which has electron inertia, but not the Hall drift) and extended MHD (which has both effects) are established. The helicities (two in all) for each of these models are obtained through these correspondences. The commonality of all the extended MHD models is traced to the existence of two Lie-dragged 2-forms, which are closely associated with the canonical momenta of the two underlying species. The Lie-dragging of these 2-forms by suitable velocities also leads to the correct equations of motion. The Hall MHD Poisson bracket is analyzed in detail, the Jacobi identity is verified through a detailed proof, and this proof ensures the Jacobi identity for the Poisson brackets of all the models.

  11. The geometry of branes and extended superspaces

    NASA Astrophysics Data System (ADS)

    Chryssomalakos, C.; de Azcárraga, J. A.; Izquierdo, J. M.; Pérez Bueno, J. C.

    We argue that a description of supersymmetric extended objects from a unified geometric point of view requires an enlargement of superspace. To this aim we study in a systematic way how superspace groups and algebras arise from Grassmann spinors when these are assumed to be the only primary entities. In the process, we recover generalized space-time superalgebras and extensions of supersymmetry found earlier. The enlargement of ordinary superspace with new parameters gives rise to extended superspace groups, on which manifestly supersymmetric actions may be constructed for various types of p-branes, including D-branes (given by Chevalley-Eilenberg cocycles) with their Born-Infeld fields. This results in a field/extended superspace democracy for superbranes: all brane fields appear as pull-backs from a suitable target superspace. Our approach also clarifies some facts concerning the origin of the central charges for the different p-branes.

  12. Extended inflation from higher dimensional theories

    NASA Technical Reports Server (NTRS)

    Holman, Richard; Kolb, Edward W.; Vadas, Sharon L.; Wang, Yun

    1990-01-01

    The possibility is considered that higher dimensional theories may, upon reduction to four dimensions, allow extended inflation to occur. Two separate models are analayzed. One is a very simple toy model consisting of higher dimensional gravity coupled to a scalar field whose potential allows for a first-order phase transition. The other is a more sophisticated model incorporating the effects of non-trivial field configurations (monopole, Casimir, and fermion bilinear condensate effects) that yield a non-trivial potential for the radius of the internal space. It was found that extended inflation does not occur in these models. It was also found that the bubble nucleation rate in these theories is time dependent unlike the case in the original version of extended inflation.

  13. Weak Lie symmetry and extended Lie algebra

    SciTech Connect

    Goenner, Hubert

    2013-04-15

    The concept of weak Lie motion (weak Lie symmetry) is introduced. Applications given exhibit a reduction of the usual symmetry, e.g., in the case of the rotation group. In this context, a particular generalization of Lie algebras is found ('extended Lie algebras') which turns out to be an involutive distribution or a simple example for a tangent Lie algebroid. Riemannian and Lorentz metrics can be introduced on such an algebroid through an extended Cartan-Killing form. Transformation groups from non-relativistic mechanics and quantum mechanics lead to such tangent Lie algebroids and to Lorentz geometries constructed on them (1-dimensional gravitational fields).

  14. NASA Orbiter Extended Nose Landing Gear

    NASA Technical Reports Server (NTRS)

    King, Steven R.; Jensen, Scott A.; Hansen, Christopher P.

    1999-01-01

    This paper discusses the design, development, test, and evaluation of a prototype Extended Nose Landing Gear (ENLG) for NASA's Space Shuttle orbiters. The ENLG is a proposed orbiter modification developed in-house at NASA's Johnson Space Center (JSC) by a joint government/industry team. It increases the orbiter's nose landing gear (NLG) length, thereby changing the vehicle's angle of attack during rollout, which lowers the aerodynamic forces on the vehicle. This, in combination with a dynamic elevon change, will lower the loads on the orbiter's main landing gear (MLG). The extension is accomplished by adding a telescoping section to the current NLG strut that will be pneumatically extended during NLG deployment.

  15. Life extending control for rocket engines

    NASA Technical Reports Server (NTRS)

    Lorenzo, C. F.; Saus, J. R.; Ray, A.; Carpino, M.; Wu, M.-K.

    1992-01-01

    The concept of life extending control is defined. A brief discussion of current fatigue life prediction methods is given and the need for an alternative life prediction model based on a continuous functional relationship is established. Two approaches to life extending control are considered: (1) the implicit approach which uses cyclic fatigue life prediction as a basis for control design; and (2) the continuous life prediction approach which requires a continuous damage law. Progress on an initial formulation of a continuous (in time) fatigue model is presented. Finally, nonlinear programming is used to develop initial results for life extension for a simplified rocket engine (model).

  16. Extending the ADM formalism to Weyl geometry

    SciTech Connect

    Barreto, A. B.; Almeida, T. S.; Romero, C.

    2015-03-26

    In order to treat quantum cosmology in the framework of Weyl spacetimes we take the first step of extending the Arnowitt-Deser-Misner formalism to Weyl geometry. We then obtain an expression of the curvature tensor in terms of spatial quantities by splitting spacetime in (3+l)-dimensional form. We next write the Lagrangian of the gravitation field based in Weyl-type gravity theory. We extend the general relativistic formalism in such a way that it can be applied to investigate the quantum cosmology of models whose spacetimes are endowed with a Weyl geometrical structure.

  17. Emergent lattices with geometrical frustration in doped extended Hubbard models

    NASA Astrophysics Data System (ADS)

    Kaneko, Ryui; Tocchio, Luca F.; Valentí, Roser; Gros, Claudius

    2016-11-01

    Spontaneous charge ordering occurring in correlated systems may be considered as a possible route to generate effective lattice structures with unconventional couplings. For this purpose we investigate the phase diagram of doped extended Hubbard models on two lattices: (i) the honeycomb lattice with on-site U and nearest-neighbor V Coulomb interactions at 3 /4 filling (n =3 /2 ) and (ii) the triangular lattice with on-site U , nearest-neighbor V , and next-nearest-neighbor V' Coulomb interactions at 3 /8 filling (n =3 /4 ). We consider various approaches including mean-field approximations, perturbation theory, and variational Monte Carlo. For the honeycomb case (i), charge order induces an effective triangular lattice at large values of U /t and V /t , where t is the nearest-neighbor hopping integral. The nearest-neighbor spin exchange interactions on this effective triangular lattice are antiferromagnetic in most of the phase diagram, while they become ferromagnetic when U is much larger than V . At U /t ˜(V/t ) 3 , ferromagnetic and antiferromagnetic exchange interactions nearly cancel out, leading to a system with four-spin ring-exchange interactions. On the other hand, for the triangular case (ii) at large U and finite V', we find no charge order for small V , an effective kagome lattice for intermediate V , and one-dimensional charge order for large V . These results indicate that Coulomb interactions induce [case (i)] or enhance [case(ii)] emergent geometrical frustration of the spin degrees of freedom in the system, by forming charge order.

  18. On energy conservation in extended magnetohydrodynamics

    SciTech Connect

    Kimura, Keiji; Morrison, P. J.

    2014-08-15

    A systematic study of energy conservation for extended magnetohydrodynamic models that include Hall terms and electron inertia is performed. It is observed that commonly used models do not conserve energy in the ideal limit, i.e., when viscosity and resistivity are neglected. In particular, a term in the momentum equation that is often neglected is seen to be needed for conservation of energy.

  19. Interpolation of the Extended Boolean Retrieval Model.

    ERIC Educational Resources Information Center

    Zanger, Daniel Z.

    2002-01-01

    Presents an interpolation theorem for an extended Boolean information retrieval model. Results show that whenever two or more documents are similarly ranked at any two points for a query containing exactly two terms, then they are similarly ranked at all points in between; and that results can fail for queries with more than two terms. (Author/LRW)

  20. Extended Learning: What Are the States Doing?

    ERIC Educational Resources Information Center

    Brown, Cynthia G.

    2001-01-01

    The standards movement and family work schedules are major factors underpinning the expansion of extended learning opportunities. A recent report by the Council of Chief State School Officials details the development of afterschool and other programs in California, Illinois, Kentucky, Massachusetts, Minnesota, and Texas. (MLH)

  1. Extending the Agricultural Extension Model. Preliminary Draft.

    ERIC Educational Resources Information Center

    Rogers, Everett M.; And Others

    The purposes of this report are: to describe the main elements of the U.S. agricultural extension model and its effects on the agricultural revolution; to analyze attempts to extend this model to non-agricultural technology and/or to less developed countries; and to draw general conclusions about the diffusion of technological innovations, with…

  2. Extended-release trazodone (Oleptro) for depression.

    PubMed

    2010-11-15

    The FDA has approved the marketing of an extended-release formulation of trazodone (Oleptro--Angelini Labopharm) for treatment of major depressive disorder in adults. Immediate-release trazodone has been available for treatment of depression for many years, but is used mostly in low doses for its sedating effects.

  3. Integrable extended van der Waals model

    NASA Astrophysics Data System (ADS)

    Giglio, Francesco; Landolfi, Giulio; Moro, Antonio

    2016-10-01

    Inspired by the recent developments in the study of the thermodynamics of van der Waals fluids via the theory of nonlinear conservation laws and the description of phase transitions in terms of classical (dissipative) shock waves, we propose a novel approach to the construction of multi-parameter generalisations of the van der Waals model. The theory of integrable nonlinear conservation laws still represents the inspiring framework. Starting from a macroscopic approach, a four parameter family of integrable extended van der Waals models is indeed constructed in such a way that the equation of state is a solution to an integrable nonlinear conservation law linearisable by a Cole-Hopf transformation. This family is further specified by the request that, in regime of high temperature, far from the critical region, the extended model reproduces asymptotically the standard van der Waals equation of state. We provide a detailed comparison of our extended model with two notable empirical models such as Peng-Robinson and Soave's modification of the Redlich-Kwong equations of state. We show that our extended van der Waals equation of state is compatible with both empirical models for a suitable choice of the free parameters and can be viewed as a master interpolating equation. The present approach also suggests that further generalisations can be obtained by including the class of dispersive and viscous-dispersive nonlinear conservation laws and could lead to a new type of thermodynamic phase transitions associated to nonclassical and dispersive shock waves.

  4. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  5. 14 CFR 1274.207 - Extended agreements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as new cooperative agreements. Continued performance within a period specified under a multiple year....207 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION COOPERATIVE AGREEMENTS WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.207 Extended agreements. (a) Multiple year...

  6. Q-Method Extended Kalman Filter

    NASA Technical Reports Server (NTRS)

    Zanetti, Renato; Ainscough, Thomas; Christian, John; Spanos, Pol D.

    2012-01-01

    A new algorithm is proposed that smoothly integrates non-linear estimation of the attitude quaternion using Davenport s q-method and estimation of non-attitude states through an extended Kalman filter. The new method is compared to a similar existing algorithm showing its similarities and differences. The validity of the proposed approach is confirmed through numerical simulations.

  7. Extending Word Processing for Foreign Characters.

    ERIC Educational Resources Information Center

    Melby, Alan K.

    1984-01-01

    Presents short text in French and discusses possible methods of extending word processing to allow text entry, text editing, and hard copy output of foreign characters. Highlights include discussions of using ASCII for English and problems with French, one-character and two-character approaches, and examples in terms of specific microcomputer…

  8. Extending the Use of Saramaccan in Suriname.

    ERIC Educational Resources Information Center

    Glock, Naomi

    1983-01-01

    Advocates the use of the vernacular language, not only as an important vehicle for learning, but also as a means of enhancing the native speakers' feeling of self-worth. Presents several ways of extending the use of the vernacular, as well as the problems that can arise. (EKN)

  9. Extending Program Resources: Meeting Necessity with Invention.

    ERIC Educational Resources Information Center

    Fuston, Judith; Hargens, Mark

    This document describes collaborative strategies used by one school guidance department that allow counselors to complete their designated work without extending their school day. One strategy involves pairing mentors with first-year counselors to help answer their questions. Another uses retired counselors as "substitutes" when regular…

  10. Collaborating for Success: Merritt Elementary Extended School.

    ERIC Educational Resources Information Center

    Woodruff, Darren W.; Shannon, Nancy R.; Efimba, Maloke O.

    1998-01-01

    Describes the Emma Francis Grayson Merritt School, Washington (District of Columbia) which has been a Comer school since 1990. The Merritt Elementary Extended School has created a foundation for educational progress and student achievement based on adult collaboration and a nurturing and developmentally sound approach to student learning. (SLD)

  11. Adult Day Care--Extended Family.

    ERIC Educational Resources Information Center

    Smith, Bert Kruger

    This pamphlet describes a multi-purpose day-care center for the elderly in Abilene, Texas which is intended to fill the "extended family" role of offering companionship, medical attention, and other aspects of concern to older persons in the community. The goals of the program are as follows: (1) to keep individuals out of institutions…

  12. Some Remarks on the Extended Galilean Transformation.

    ERIC Educational Resources Information Center

    Greenberger, Daniel M.

    1979-01-01

    The extended Galilean transformation carries an inertial frame into a rigid frame with uniform spatial, but arbitrary translational acceleration. Besides being useful in discussing the equivalence principle, this transformation provides a physical interpretation for the theorem in nonrelativistic quantum mechanics, that we cannot coherently…

  13. Robotic extended pyelolithotomy for complete staghorn calculus.

    PubMed

    Sotelo, Rene; Astigueta, Juan Carlos; Giedelman, Camilo; de Andrade, Robert; Carmona, Oswaldo; Ramirez, Daniel; Clavijo, Rafael

    2010-08-01

    Staghorn stones represent a therapeutic challenge to urologists. We present our experience with laparoscopic extended pyelolithotomy for treatment of staghorn and complex renal calculi in highly selected cases. This approach provides the principles of open surgery with the advantages of minimally invasive surgery. We describe our experience with robot-assisted extended pyelolithotomy for complex coralliform calculi. Since January 2007, robotic extended pyelolithotomy has been performed by transperitoneal approach in two patients with complete coralliform lithiasis (calculi average size 8 cm). One patient had history of percutaneous nephrolithotomy. Demographic and operative data were collected. All procedures were technically successful without need for open conversion. Mean estimated blood loss was 175 ml (range 50-300 ml), and mean operative time was 150 min (range 120-150 min). A perinephric drain was employed in one patient with duration of 5 days. Postoperative imaging confirmed complete stone clearance. Robotic extended pyelolithotomy is a feasible and reproducible procedure for removal of complete and partial staghorn calculi in selected patients with complex nephrolithiasis. This approach might limit the role of open surgery for these calculi, but further publications with more cases are necessary to further define its utility.

  14. Mass flux in extended and classical hydrodynamics.

    PubMed

    Grmela, Miroslav

    2014-06-01

    In classical hydrodynamics, the mass flux is universally chosen to be the momentum field. In extended hydrodynamics, the mass flux acquires different terms. The extended hydrodynamics introduced and investigated in this paper uses a one-particle distribution function as the extra state variable chosen to characterize the microstructure. We prove that the extended hydrodynamics is fully autonomous in the sense that it is compatible with thermodynamics (i.e., the entropy does not decrease during the time evolution) and with mechanics (i.e., the part of the time evolution that leaves the entropy unchanged is Hamiltonian). Subsequently, we investigate its possible reductions. In some situations the emerging reduced dynamical theory is the classical hydrodynamics that is fully autonomous (i.e., all the structure that makes the extended theory fully autonomous is kept in the reduced theory). In other situations (for example, when the fluids under investigation have large density gradients) the reduced theories are not fully autonomous. In such a case the reduced theories constitute a family of mutually related dynamical theories (each of them involving a different amount of detail) that we consider to be a mathematical formulation of multiscale (or multilevel) hydrodynamics. It is in the reduced theories belonging to the multiscale hydrodynamics where the terms that emerge in the mass flux take the form of self-diffusion.

  15. The inflation sector of extended inflation

    SciTech Connect

    Kolb, E.W. Chicago Univ., IL )

    1990-11-01

    In extended inflation the inflationary era is brought to a close by the process of percolation of true vacuum bubbles produced in a first-order phase transition. In this paper I discuss several effects that might obtain if the Universe undergoes an inflationary first-order phase transition. 17 refs.

  16. The Extended Family and Children's Educational Success

    ERIC Educational Resources Information Center

    Jaeger, Mads Meier

    2012-01-01

    Research on family background and educational success focuses almost exclusively on two generations: parents and children. This study argues that the extended family contributes significantly to the total effect of family background on educational success. Analyses using the Wisconsin Longitudinal Study show that, net of family factors shared by…

  17. Extended Generalized Linear Latent and Mixed Model

    ERIC Educational Resources Information Center

    Segawa, Eisuke; Emery, Sherry; Curry, Susan J.

    2008-01-01

    The generalized linear latent and mixed modeling (GLLAMM framework) includes many models such as hierarchical and structural equation models. However, GLLAMM cannot currently accommodate some models because it does not allow some parameters to be random. GLLAMM is extended to overcome the limitation by adding a submodel that specifies a…

  18. Elaborated Odor Test for Extended Exposure

    NASA Technical Reports Server (NTRS)

    Buchanan, Vanessa D.; Henry, Emily J.; Mast, Dion J.; Harper, Susana A.; Beeson, Harold D.; Tapia, Alma S.

    2016-01-01

    Concerns were raised when incidental exposure to a proprietary bonding material revealed the material had an irritating odor. The NASA-STD-6001B document describes a supplemental test method option for programs to evaluate materials with odor concerns (Test 6, Odor Assessment). In addition to the supplemental standard odor assessment with less than 10 seconds of exposure, the NASA White Sands Test Facility (WSTF) Materials Flight Acceptance Testing section was requested to perform an odor test with an extended duration to evaluate effects of an extended exposure and to more closely simulate realistic exposure scenarios. With approval from the NASA Johnson Space Center Industrial Hygienist, WSTF developed a 15-minute odor test method. WSTF performed this extended-duration odor test to evaluate the odor and physical effects of the bonding material configured between two aluminum plates, after the safety of the gas was verified via toxicity analysis per NASA-STD-6001B Test 7, Determination of Offgassed Products. During extended-duration testing, odor panel members were arranged near the test material in a small room with the air handlers and doors closed to minimize dilution. The odor panel members wafted gas toward themselves and recorded their individual assessments of odor and physical effects at various intervals during the 15-minute exposure and posttest. A posttest interview was conducted to obtain further information. Testing was effective in providing data for comparison and selection of an optimal offgassing and odor containment configuration. The developed test method for extended exposure is proposed as a useful tool for further evaluating materials with identified odors of concern if continued use of the material is anticipated.

  19. Mechanics of isolated extended bodies in classical field theories

    NASA Astrophysics Data System (ADS)

    Harte, Abraham Isaiah

    2007-08-01

    This thesis discusses a number of issues related to the description and motion of extended matter distributions in certain classical field theories. Particular emphasis is placed on general relativity and Maxwell theory, although many results also apply in related formalisms. They are obtained by extending and applying a series of ideas originally developed by W. G. Dixon to understand the mechanics of isolated bodies. Since this formalism is not well- known, we provide an extensive review in a unified form. This elucidates the structure of an object's stress-energy tensor and electromagnetic current vector. Multipole decompositions of these objects are also studied in considerable detail, and are designed to automatically "factor out" the relevant conservation laws. In the case of charge-current vectors, we show how to extend these results to also take into account the assumed smoothness and compactness of the physical matter. This allows essentially all reasonable current configurations with a given total charge to be parameterized without any reference to the spacetime structure. Such constructions provide natural methods for comparing the properties of current distributions in different systems. They also simplify the study of "rigid" currents. It is found that such objects cannot generally exist without allowing for the presence of singularities. An even stronger result applies to the nonexistence of rigid number density vectors in systems where the total number of particles is fixed. These formal developments are applied in various way to study the motions of various compact extended bodies. The first case considered here is that of an uncharged test mass embedded in a spatially-flat Friedmann-Robertson-Walker universe. It is shown that even with zero (global) momentum, such an object may adjust its mass and trajectory merely by changing shape. Mass shifts are in fact unavoidable in almost all cases, and could be significant for galactic superclusters. This

  20. Theoretical studies of molecular interactions

    SciTech Connect

    Lester, W.A. Jr.

    1993-12-01

    This research program is directed at extending fundamental knowledge of atoms and molecules including their electronic structure, mutual interaction, collision dynamics, and interaction with radiation. The approach combines the use of ab initio methods--Hartree-Fock (HF) multiconfiguration HF, configuration interaction, and the recently developed quantum Monte Carlo (MC)--to describe electronic structure, intermolecular interactions, and other properties, with various methods of characterizing inelastic and reaction collision processes, and photodissociation dynamics. Present activity is focused on the development and application of the QMC method, surface catalyzed reactions, and reorientation cross sections.

  1. The new neutron rich nuclei

    SciTech Connect

    Gridnev, K. A.; Gridnev, D. K.; Tarasov, V. N.; Tarasov, D. V.; Viñas, X.; Greiner, W.

    2014-07-23

    Using HF+BCS method with Skyrme forces we analyze the neutron drip line. It is shown that around magic and new magic numbers the drip line may form stability peninsulas. It is shown that the location of these peninsulas does not depend on the choice of Skyrme forces. It is found that the size of the peninsulas is sensitive to the choice of Skyrme forces and the most extended peninsulas appear with the SkI2 set.

  2. Extended law of corresponding states for protein solutions

    NASA Astrophysics Data System (ADS)

    Platten, Florian; Valadez-Pérez, Néstor E.; Castañeda-Priego, Ramón; Egelhaaf, Stefan U.

    2015-05-01

    The so-called extended law of corresponding states, as proposed by Noro and Frenkel [J. Chem. Phys. 113, 2941 (2000)], involves a mapping of the phase behaviors of systems with short-range attractive interactions. While it has already extensively been applied to various model potentials, here we test its applicability to protein solutions with their complex interactions. We successfully map their experimentally determined metastable gas-liquid binodals, as available in the literature, to the binodals of short-range square-well fluids, as determined by previous as well as new Monte Carlo simulations. This is achieved by representing the binodals as a function of the temperature scaled with the critical temperature (or as a function of the reduced second virial coefficient) and the concentration scaled by the cube of an effective particle diameter, where the scalings take into account the attractive and repulsive contributions to the interaction potential, respectively. The scaled binodals of the protein solutions coincide with simulation data of the adhesive hard-sphere fluid. Furthermore, once the repulsive contributions are taken into account by the effective particle diameter, the temperature dependence of the reduced second virial coefficients follows a master curve that corresponds to a linear temperature dependence of the depth of the square-well potential. We moreover demonstrate that, based on this approach and cloud-point measurements only, second virial coefficients can be estimated, which we show to agree with values determined by light scattering or by Derjaguin-Landau-Verwey-Overbeek (DLVO)-based calculations.

  3. Extended operator expansion method for neutrinoless double beta decay

    NASA Astrophysics Data System (ADS)

    Hirsch, M.; Kadowaki, O.; Klapdor-Kleingrothaus, H. V.; Muto, K.; Oda, T.

    1995-03-01

    Reliable calculations of nuclear matrix elements are a prerequisite for the determination of the effective neutrino mass and other particle physics parameters from neutrinoless double beta decay. Here, the operator expansion method is improved by including Coulomb, tensor and central interactions simultaneously. Furthermore, the formalism of the OEM is extended to those matrix elements necessary to extract the right-handed parameters < λ > and < η > from 0 νββ decay. OEM includes the dependence of the nuclear matrix elements on the intermediate states implicitly and can therefore be understood as a step beyond the closure approximation. Numerical studies are carried out for the isotope76Ge combining the OEM expressions with ground-state wave functions calculated within a proton-neutron quasiparticle Random Phase Approximation (pn-QRPA) model. The influence and relative importance of central, tensor and Coulomb interactions is investigated. Within the OEM, contributions from the Coulomb force are found to be negligible in 0 νββ decay, while the tensor force leads to a moderate change of the results, of the order of (10 30)%, giving a better agreement between sets of calculations which employ different NN-interactions. Generally, results of the OEM+QRPA calculation are similar to previous calculations of 0 νββ decay matrix elements, indicating that 0 νββ decay is not sensitive to model approximations and might therefore be more accurately calculated than the strongly suppressed 2 νββ decay matrix elements.

  4. Design and Synthesis of Hydroxyethylene-Based BACE-1 Inhibitors Incorporating Extended P1 Substituents

    PubMed Central

    Sandgren, Veronica; Bäck, Marcus; Kvarnström, Ingemar; Dahlgren, Anders

    2013-01-01

    Novel BACE-1 inhibitors with a hydroxyethylene central core have been developed. Modified P1´ and extended P1 substituents were incorporated with the aim to explore potential interactions with the S1´ and the S1-S3 pocket, respectively, of BACE-1. Inhibitors were identified displaying IC50 values in the nanomolar range, i.e. 69 nM for the most potent compound. Possible inhibitor interactions with the enzyme are also discussed. PMID:23585822

  5. Optimizing Extender Code for NCSX Analyses

    SciTech Connect

    M. Richman, S. Ethier, and N. Pomphrey

    2008-01-22

    Extender is a parallel C++ code for calculating the magnetic field in the vacuum region of a stellarator. The code was optimized for speed and augmented with tools to maintain a specialized NetCDF database. Two parallel algorithms were examined. An even-block work-distribution scheme was comparable in performance to a master-slave scheme. Large speedup factors were achieved by representing the plasma surface with a spline rather than Fourier series. The accuracy of this representation and the resulting calculations relied on the density of the spline mesh. The Fortran 90 module db access was written to make it easy to store Extender output in a manageable database. New or updated data can be added to existing databases. A generalized PBS job script handles the generation of a database from scratch

  6. Is XTE J1701-407 Extended?

    NASA Astrophysics Data System (ADS)

    Kaplan, David

    2007-09-01

    We recently observed the neutron star X-ray transient XTE J1701-407 with Chandra, using 1 ks of ACIS-S data for localization. However, the Chandra data do not show a point source. Instead the source appears extended over ~6 arcsec. We have investigated the data, consulting with experts both at MIT and SAO, and cannot ascribe the data to purely instrumental effects (aspect errors or pileup). The extended X-ray emission could come from an outflow or a dust scattering halo - both very interesting and rare phenomena. Jets allow detailed calorimetry of the outbursts, while scattering halos lead to geometric distances. We request a 5 ks ACIS-S subarray observation to definitively assess the morphology, trying to discriminate between these scenarios before the target fades into quiescence.

  7. Junction conditions in extended Teleparallel gravities

    SciTech Connect

    De la Cruz-Dombriz, Álvaro; Dunsby, Peter K.S.; Sáez-Gómez, Diego E-mail: peter.dunsby@uct.ac.za

    2014-12-01

    In the context of extended Teleparallel gravity theories, we address the issue of junction conditions required to guarantee the correct matching of different regions of spacetime. In the absence of shells/branes, these conditions turn out to be more restrictive than their counterparts in General Relativity as in other extended theories of gravity. In fact, the general junction conditions on the matching hypersurfaces depend on the underlying theory and a new condition on the induced tetrads in order to avoid delta-like distributions in the field equations. This result imposes strict consequences on the viability of standard solutions such as the Einstein-Straus-like construction. We find that the continuity of the scalar torsion is required in order to recover the usual General Relativity results.

  8. Extending resolution limits of EUV resist materials

    NASA Astrophysics Data System (ADS)

    Krysak, Marie; Leeson, Michael; Han, Eungnak; Blackwell, James; Harlson, Shane

    2015-03-01

    Extreme ultraviolet lithography (EUVL) technology continues to progress and remains a viable candidate for next generation lithography1, which drives the need for EUV resists capable of high resolution with high sensitivity and low LWR. While chemically amplified resists (CARs) have demonstrated the ability to pattern 12nm half-pitch features2, pattern collapse continues to limit their ultimate resolution. We have taken multiple approaches to extend resist capabilities past these limits. Recent results in pattern collapse mitigation using a resist encapsulation and etch back strategy will be discussed. We continue to investigate EUV patterning of semi-inorganic resists to simultaneously increase EUV photon absorption and extend mechanical strength beyond CAR capabilities. The limitations of metal oxide-based nanoparticle photoresists have been investigated, and have provided key insights to further understanding the mechanism of this class of materials.

  9. Top partner probes of extended Higgs sectors

    NASA Astrophysics Data System (ADS)

    Kearney, John; Pierce, Aaron; Thaler, Jesse

    2013-08-01

    Natural theories of the weak scale often include fermionic partners of the top quark. If the electroweak symmetry breaking sector contains scalars beyond a single Higgs doublet, then top partners can have sizable branching ratios to these extended Higgs sector states. In fact, top partner decays may provide the most promising discovery mode for such scalars, especially given the large backgrounds to direct and associated production. In this paper, we present a search strategy for top partner decays to a charged Higgs boson and a bottom quark, focusing on the case where the charged Higgs dominantly decays to third-generation quarks to yield a multi- b final state. We also discuss ways to extend this search to exotic neutral scalars decaying to bottom quark pairs.

  10. Extended target recognition in cognitive radar networks.

    PubMed

    Wei, Yimin; Meng, Huadong; Liu, Yimin; Wang, Xiqin

    2010-01-01

    We address the problem of adaptive waveform design for extended target recognition in cognitive radar networks. A closed-loop active target recognition radar system is extended to the case of a centralized cognitive radar network, in which a generalized likelihood ratio (GLR) based sequential hypothesis testing (SHT) framework is employed. Using Doppler velocities measured by multiple radars, the target aspect angle for each radar is calculated. The joint probability of each target hypothesis is then updated using observations from different radar line of sights (LOS). Based on these probabilities, a minimum correlation algorithm is proposed to adaptively design the transmit waveform for each radar in an amplitude fluctuation situation. Simulation results demonstrate performance improvements due to the cognitive radar network and adaptive waveform design. Our minimum correlation algorithm outperforms the eigen-waveform solution and other non-cognitive waveform design approaches.

  11. An extended retinotopic map of mouse cortex

    PubMed Central

    Zhuang, Jun; Ng, Lydia; Williams, Derric; Valley, Matthew; Li, Yang; Garrett, Marina; Waters, Jack

    2017-01-01

    Visual perception and behavior are mediated by cortical areas that have been distinguished using architectonic and retinotopic criteria. We employed fluorescence imaging and GCaMP6 reporter mice to generate retinotopic maps, revealing additional regions of retinotopic organization that extend into barrel and retrosplenial cortices. Aligning retinotopic maps to architectonic borders, we found a mismatch in border location, indicating that architectonic borders are not aligned with the retinotopic transition at the vertical meridian. We also assessed the representation of visual space within each region, finding that four visual areas bordering V1 (LM, P, PM and RL) display complementary representations, with overlap primarily at the central hemifield. Our results extend our understanding of the organization of mouse cortex to include up to 16 distinct retinotopically organized regions. DOI: http://dx.doi.org/10.7554/eLife.18372.001 PMID:28059700

  12. Extended ion pumped vacuum friction test

    NASA Technical Reports Server (NTRS)

    Hammel, R. L.

    1971-01-01

    Boundary layer friction data under ion pumped vacuum was taken for sixteen material couples. The test series was an extension of a previous study of the effects of modified ion pumped environments. Sliding distances imposed in the present effort greatly exceeded any studied in the previous contiguous, flight or ground tests. Wear out of specific couples, in particular, thin film lubricants was noted. The behavior of the test hardware including wear out of the mechanisms was noted. As a result, the impact of test interruption was observed for several test couples. Recovery of the friction upon re-establishing sliding in vacuum was generally rapid. The results of the extended sliding study reinforce the previous conclusion that sliding distance (mechanical history) is the primary factor in establishing the force limiting boundary layer friction. General friction value under the extended sliding confirm those observed in previous orbital and the related ground test studies.

  13. Extending The Shelf Life Of Blood Platelets

    NASA Technical Reports Server (NTRS)

    Surgenor, Douglas M.

    1988-01-01

    New method of storing human blood platelets extends vitality for transfusions. Packaged as suspension in sterile liquid in plastic blood bags. Each bag placed between pair of plastic grids, and rubberbands placed around sandwich thus formed to hold together. Stored upright in open air or in container through which air pumped at rate of at least 45 L/min. Ensures that platelets receive ample oxygen and expiratory carbon dioxide form platelets removed before pH drops to harmful levels.

  14. Extending Installation Sustainability Beyond the Fenceline

    DTIC Science & Technology

    2010-06-01

    Office of the Assistant Secretary of the Army (Installations and Environment) DoD Executive Agent Extending Installation Sustainability Beyond...Technology Transition – Supporting DoD Readiness, Sustainability , and the Warfighter Report Documentation Page Form ApprovedOMB No. 0704-0188 Public...if it does not display a currently valid OMB control number. 1. REPORT DATE JUN 2010 2. REPORT TYPE 3. DATES COVERED 00-00-2010 to 00-00-2010

  15. Extended Temperature Solar Cell Technology Development

    NASA Technical Reports Server (NTRS)

    Landis, Geoffrey A.; Jenkins, Phillip; Scheiman, David; Rafaelle, Ryne

    2004-01-01

    Future NASA missions will require solar cells to operate both in regimes closer to the sun, and farther from the sun, where the operating temperatures will be higher and lower than standard operational conditions. NASA Glenn is engaged in testing solar cells under extended temperature ranges, developing theoretical models of cell operation as a function of temperature, and in developing technology for improving the performance of solar cells for both high and low temperature operation.

  16. Rugged, Tunable Extended-Cavity Diode Laser

    NASA Technical Reports Server (NTRS)

    Moore, Donald; Brinza, David; Seidel, David; Klipstein, William; Choi, Dong Ho; Le, Lam; Zhang, Guangzhi; Iniguez, Roberto; Tang, Wade

    2007-01-01

    A rugged, tunable extended-cavity diode laser (ECDL) has been developed to satisfy stringent requirements for frequency stability, notably including low sensitivity to vibration. This laser is designed specifically for use in an atomic-clock experiment to be performed aboard the International Space Station (ISS). Lasers of similar design would be suitable for use in terrestrial laboratories engaged in atomic-clock and atomic-physics research.

  17. Extended use of photovoltaic solar panels

    NASA Astrophysics Data System (ADS)

    Guazzoni, Guido E.; Rose, M. Frank

    1996-02-01

    The use of photovoltaic solar panels (and related generation of electric power) can be extended to a 24 hours per day under any environmental condition by equipping them with an artificial source of light, with emitting wavelengths matched to the photovoltaic solar panels, to be turned on in the absence of sunlight. This source of light can be obtained by heating a mantle to an incandescent temperature via the efficient, low polluting combustion of Natural Gas, Butane, Propane, or other gaseous Hydrocarbon fuel.

  18. Formatting scripts with computers and Extended BASIC.

    PubMed

    Menning, C B

    1984-02-01

    A computer program, written in the language of Extended BASIC, is presented which enables scripts, for educational media, to be quickly written in a nearly unformatted style. From the resulting script file, stored on magnetic tape or disk, the computer program formats the script into either a storyboard , a presentation, or a narrator 's script. Script headings and page and paragraph numbers are automatic features in the word processing. Suggestions are given for making personal modifications to the computer program.

  19. Extended source model for diffusive coupling.

    PubMed

    González-Ochoa, Héctor O; Flores-Moreno, Roberto; Reyes, Luz M; Femat, Ricardo

    2016-01-01

    Motivated by the prevailing approach to diffusion coupling phenomena which considers point-like diffusing sources, we derived an analogous expression for the concentration rate of change of diffusively coupled extended containers. The proposed equation, together with expressions based on solutions to the diffusion equation, is intended to be applied to the numerical solution of systems exclusively composed of ordinary differential equations, however is able to account for effects due the finite size of the coupled sources.

  20. Changing Requirements of Assurance and Extended Deterrence

    DTIC Science & Technology

    2010-07-01

    Larsen, eds., Weapons of Mass Destruction: An Encyclopedia of Worldwide Policy, Technology, and History, Vol. II (Santa Barbara, CA: ABC - CLIO, 2005...Appendix A Abbreviations ABM Anti-Ballistic Missile ABMT Anti-Ballistic Missile Treaty AEIO Atomic Energy Organization of Iran AKP Justice and... ABC -CLIO, 2005. Thranert, Oliver. “NATO, Missile Defence and Extended Deterrence.” Survival 51:6 (December2009-January 2010): 63–75. Wheeler

  1. Effects of Extended Hypoxia on Night Vision

    DTIC Science & Technology

    1983-06-01

    and Krill (5) have reported a study of fundamental sig- nificance on the effects of stimulus paraneter; and retinal placement of the stimulus on night...by Ernest and Krill (5), that the early segment of the dark adaptation function was unaffected by hypoxia. This disagreement probably can be explained...in recovery capability, even after extended hypoxia. The clear implication of this relationship for practical operetions is that supplemental oxygen

  2. Astrophysical constraints on extended gravity models

    SciTech Connect

    Lambiase, Gaetano; Stabile, Antonio; Sakellariadou, Mairi; Stabile, Arturo E-mail: mairi.sakellariadou@kcl.ac.uk E-mail: arturo.stabile@gmail.com

    2015-07-01

    We investigate the propagation of gravitational waves in the context of fourth order gravity nonminimally coupled to a massive scalar field. Using the damping of the orbital period of coalescing stellar binary systems, we impose constraints on the free parameters of extended gravity models. In particular, we find that the variation of the orbital period is a function of three mass scales which depend on the free parameters of the model under consideration; we can constrain these mass scales from current observational data.

  3. Solution of the Self-consistent Skyrme Hartree-Fock-Bogoliubov Equations in the Cartesian Deformed Harmonic Oscillator Bssis (VII_HFODD (v.2.73y): a new version of the jprogram

    SciTech Connect

    Schunck, N.; Dobaczewski, J.; Satula, W.; Baczyk, P.; Dudek, J.; Gao, Y.; Konieczka, M.; Sato, K.; Shi, Y.; Wang, X. B.; Werner, T. R.

    2016-10-05

    HFODD is a physics computer code that is used to model the structure of the nucleus. It is an implimentation of the nuclear energy Density Functional Theory (DFT), where the energy of the nucleus is obtained by intergration over space of some phenomenological energy density, which is itself a functional of the neutron and proton densities. In HFODD, the energy density derives from either the Skyre or the Gogny effective two-body interaction between nucleons. Nuclear super-fluidity is treated a the Hartree-Fock-Boboliubov (HFB) approximation. This version is the 8th release of the code; the 7 previous versions have been published in Computer Physics Communications (see references). Version 2.49p was partly developed at LLNL and was released under a GPL License and IM number LLNL-CODE-470611. The currect version 2.73y is the second version that has been partly developed a LLNL.

  4. Extending the ICRF to Higher Radio Frequencies

    NASA Technical Reports Server (NTRS)

    Jacobs, C. S.; Jones, D. L.; Lanyi, G. E.; Lowe, S. T.; Naudet, C. J.; Resch, G. M.; Steppe, J. A.; Zhang, L. D.; Ulvestad, J. S.; Taylor, G. B.

    2002-01-01

    The ICRF forms the basis for all astrometry including use as the inertial coordinate system for navigating deep space missions. This frame was defined using S/X-band observations over the past 20+ years. In January 2002, the VLBA approved our proposal for observing time to extend the ICRF to K-band (24 GHz) and Q-band (43 GHz). The first step will be observations at K- and Q-bands on a subset of ICRF sources. Eventually, K- and Q-band multi-epoch observations will be used to estimate positions, flux density and source structure for a large fraction of the current S/X-band ICRF source list. This work will benefit the radio astronomy community by extending the VLBA calibrator list at these bands. In the longer term, we would also like to extend the ICRF to Ka-band (32 GHz). A celestial reference frame will be needed at this frequency to support deep space navigation. A navigation demonstration is being considered for NASA's Mars 2005 mission. The initial K- and Q-band work will serve to identify candidate sources at Ka-band for use with that mission.

  5. An extended active control for chaos synchronization

    NASA Astrophysics Data System (ADS)

    Tang, Rong-An; Liu, Ya-Li; Xue, Ju-Kui

    2009-04-01

    By introducing a control strength matrix, the active control theory in chaotic synchronization is developed. With this extended method, chaos complete synchronization can be achieved more easily, i.e., a much smaller control signal is enough to reach synchronization in most cases. Numerical simulations on Rossler, Liu's four-scroll, and Chen system confirmed this and show that the synchronization result depends on the control strength significantly. Especially, in the case of Liu and Chen systems, the response systems' largest Lyapunov exponents' variation with the control strength is not monotone and there exist minima. It is novel for Chen system that the synchronization speed with a special small strength is higher than that of the usual active control which, as a special case of the extended method, has a much larger control strength. All these results indicate that the control strength is an important factor in the actual synchronization. So, with this extended active control, one can make a better and more practical synchronization scheme by adjusting the control strength matrix.

  6. Origin of density fluctuations in extended inflation

    NASA Technical Reports Server (NTRS)

    Kolb, Edward W.; Salopek, David S.; Turner, Michael S.

    1990-01-01

    The density fluctuations (both curvature and isocurvature) that arise due to quantum fluctuations in a simple model of extended inflation based upon the Jordan-Brans-Dicke theory are calculated. Curvature fluctuations arise due to quantum fluctuations in the Brans-Dicke field, in general have a nonscale-invariant spectrum, and can have an amplitude that is cosmologically acceptable and interesting without having to tune any coupling constant to a very small value. The density perturbations that arise due to the inflation field are subdominant. If there are other massless fields in the theory, e.g., an axion or an ilion, then isocurvature fluctuations arise in these fields too. Production of gravitational waves and the massless particles associated with excitations of the Brans-Dicke field are also discussed. Several attempts at more realistic models of extended inflation are also analyzed. The importance of the Einstein conformal frame in calculating curvature fluctuations is emphasized. When viewed in this frame, extended inflation closely resembles slow-rollover inflation with an exponential potential and the usual formula for the amplitude of curvature perturbations applies.

  7. Extended image differencing for change detection in UAV video mosaics

    NASA Astrophysics Data System (ADS)

    Saur, Günter; Krüger, Wolfgang; Schumann, Arne

    2014-03-01

    Change detection is one of the most important tasks when using unmanned aerial vehicles (UAV) for video reconnaissance and surveillance. We address changes of short time scale, i.e. the observations are taken in time distances from several minutes up to a few hours. Each observation is a short video sequence acquired by the UAV in near-nadir view and the relevant changes are, e.g., recently parked or moved vehicles. In this paper we extend our previous approach of image differencing for single video frames to video mosaics. A precise image-to-image registration combined with a robust matching approach is needed to stitch the video frames to a mosaic. Additionally, this matching algorithm is applied to mosaic pairs in order to align them to a common geometry. The resulting registered video mosaic pairs are the input of the change detection procedure based on extended image differencing. A change mask is generated by an adaptive threshold applied to a linear combination of difference images of intensity and gradient magnitude. The change detection algorithm has to distinguish between relevant and non-relevant changes. Examples for non-relevant changes are stereo disparity at 3D structures of the scene, changed size of shadows, and compression or transmission artifacts. The special effects of video mosaicking such as geometric distortions and artifacts at moving objects have to be considered, too. In our experiments we analyze the influence of these effects on the change detection results by considering several scenes. The results show that for video mosaics this task is more difficult than for single video frames. Therefore, we extended the image registration by estimating an elastic transformation using a thin plate spline approach. The results for mosaics are comparable to that of single video frames and are useful for interactive image exploitation due to a larger scene coverage.

  8. Astrocytic mitochondrial membrane hyperpolarization following extended oxygen and glucose deprivation.

    PubMed

    Korenić, Andrej; Boltze, Johannes; Deten, Alexander; Peters, Myriam; Andjus, Pavle; Radenović, Lidija

    2014-01-01

    Astrocytes can tolerate longer periods of oxygen and glucose deprivation (OGD) as compared to neurons. The reasons for this reduced vulnerability are not well understood. Particularly, changes in mitochondrial membrane potential (Δψ(m)) in astrocytes, an indicator of the cellular redox state, have not been investigated during reperfusion after extended OGD exposure. Here, we subjected primary mouse astrocytes to glucose deprivation (GD), OGD and combinations of both conditions varying in duration and sequence. Changes in Δψ(m), visualized by change in the fluorescence of JC-1, were investigated within one hour after reconstitution of oxygen and glucose supply, intended to model in vivo reperfusion. In all experiments, astrocytes showed resilience to extended periods of OGD, which had little effect on Δψ(m) during reperfusion, whereas GD caused a robust Δψ(m) negativation. In case no Δψ(m) negativation was observed after OGD, subsequent chemical oxygen deprivation (OD) induced by sodium azide caused depolarization, which, however, was significantly delayed as compared to normoxic group. When GD preceded OD for 12 h, Δψ(m) hyperpolarization was induced by both GD and subsequent OD, but significant interaction between these conditions was not detected. However, when GD was extended to 48 h preceding OGD, hyperpolarization enhanced during reperfusion. This implicates synergistic effects of both conditions in that sequence. These findings provide novel information regarding the role of the two main substrates of electron transport chain (glucose and oxygen) and their hyperpolarizing effect on Δψ(m) during substrate deprivation, thus shedding new light on mechanisms of astrocyte resilience to prolonged ischemic injury.

  9. Dark energy and extended dark matter halos

    NASA Astrophysics Data System (ADS)

    Chernin, A. D.; Teerikorpi, P.; Valtonen, M. J.; Dolgachev, V. P.; Domozhilova, L. M.; Byrd, G. G.

    2012-03-01

    The cosmological mean matter (dark and baryonic) density measured in the units of the critical density is Ωm = 0.27. Independently, the local mean density is estimated to be Ωloc = 0.08-0.23 from recent data on galaxy groups at redshifts up to z = 0.01-0.03 (as published by Crook et al. 2007, ApJ, 655, 790 and Makarov & Karachentsev 2011, MNRAS, 412, 2498). If the lower values of Ωloc are reliable, as Makarov & Karachentsev and some other observers prefer, does this mean that the Local Universe of 100-300 Mpc across is an underdensity in the cosmic matter distribution? Or could it nevertheless be representative of the mean cosmic density or even be an overdensity due to the Local Supercluster therein. We focus on dark matter halos of groups of galaxies and check how much dark mass the invisible outer layers of the halos are able to host. The outer layers are usually devoid of bright galaxies and cannot be seen at large distances. The key factor which bounds the size of an isolated halo is the local antigravity produced by the omnipresent background of dark energy. A gravitationally bound halo does not extend beyond the zero-gravity surface where the gravity of matter and the antigravity of dark energy balance, thus defining a natural upper size of a system. We use our theory of local dynamical effects of dark energy to estimate the maximal sizes and masses of the extended dark halos. Using data from three recent catalogs of galaxy groups, we show that the calculated mass bounds conform with the assumption that a significant amount of dark matter is located in the invisible outer parts of the extended halos, sufficient to fill the gap between the observed and expected local matter density. Nearby groups of galaxies and the Virgo cluster have dark halos which seem to extend up to their zero-gravity surfaces. If the extended halo is a common feature of gravitationally bound systems on scales of galaxy groups and clusters, the Local Universe could be typical or even

  10. Generalized slave-particle method for extended Hubbard models

    NASA Astrophysics Data System (ADS)

    Georgescu, Alexandru B.; Ismail-Beigi, Sohrab

    2015-12-01

    We introduce a set of generalized slave-particle models for extended Hubbard models that treat localized electronic correlations using slave-boson decompositions. Our models automatically include two slave-particle methods of recent interest, the slave-rotor and slave-spin methods, as well as a ladder of new intermediate models where one can choose which of the electronic degrees of freedom (e.g., spin or orbital labels) are treated as correlated degrees of freedom by the slave bosons. In addition, our method removes the aberrant behavior of the slave-rotor model, where it systematically overestimates the importance of electronic correlation effects for weak interaction strength, by removing the contribution of unphysical states from the bosonic Hilbert space. The flexibility of our formalism permits one to separate and isolate the effect of correlations on the key degrees of freedom.

  11. Conjugated polymer sensors built on pi-extended borasiloxane cages.

    PubMed

    Liu, Wenjun; Pink, Maren; Lee, Dongwhan

    2009-06-24

    An efficient 2 + 2 cyclocondensation with dihydroxysilane converted simple arylboronic acids to bifunctional borasiloxane cage molecules, which were subsequently electropolymerized to furnish air-stable thin films. The extended [p,pi]-conjugation that defines the rigid backbone of this new conjugated polymer (CP) motif gives rise to longer-wavelength UV-vis transitions upon oxidative doping, the spectral window and intensity of which can be modified by interaction with Lewis basic reagents. Notably, this boron-containing CP undergoes a rapid and reversible color change from green to orange upon exposure to volatile amine samples under ambient conditions. This direct naked-eye detection scheme can best be explained by invoking the reversible B-N dative bond formation that profoundly influences the p-pi* orbital overlap.

  12. Studies of acoustic emission from point and extended sources

    NASA Technical Reports Server (NTRS)

    Sachse, W.; Kim, K. Y.; Chen, C. P.

    1986-01-01

    The use of simulated and controlled acoustic emission signals forms the basis of a powerful tool for the detailed study of various deformation and wave interaction processes in materials. The results of experiments and signal analyses of acoustic emission resulting from point sources such as various types of indentation-produced cracks in brittle materials and the growth of fatigue cracks in 7075-T6 aluminum panels are discussed. Recent work dealing with the modeling and subsequent signal processing of an extended source of emission in a material is reviewed. Results of the forward problem and the inverse problem are presented with the example of a source distributed through the interior of a specimen.

  13. Tunable longitudinal modes in extended silver nanoparticle assemblies

    PubMed Central

    Bayram, Serene S; Lindfors, Klas

    2016-01-01

    Summary Nanostructured materials with tunable properties are of great interest for a wide range of applications. The self-assembly of simple nanoparticle building blocks could provide an inexpensive means to achieve this goal. Here, we generate extended anisotropic silver nanoparticle assemblies in solution using controlled amounts of one of three inexpensive, widely available, and environmentally benign short ditopic ligands: cysteamine, dithiothreitol and cysteine in aqueous solution. The self-assembly of our extended structures is enforced by hydrogen bonding. Varying the ligand concentration modulates the extent and density of these unprecedented anisotropic structures. Our results show a correlation between the chain nature of the assembly and the generation of spectral anisotropy. Deuterating the ligand further enhances the anisotropic signal by triggering more compact aggregates and reveals the importance of solvent interactions in assembly size and morphology. Spectral and morphological evolutions of the AgNPs assemblies are followed via UV–visible spectroscopy and transmission electron microscopy (TEM). Spectroscopic measurements are compared to calculations of the absorption spectra of randomly assembled silver chains and aggregates based on the discrete dipole approximation. The models support the experimental findings and reveal the importance of aggregate size and shape as well as particle polarizability in the plasmon coupling between nanoparticles. PMID:27826496

  14. Extended Kramers-Moyal analysis applied to optical trapping.

    PubMed

    Honisch, Christoph; Friedrich, Rudolf; Hörner, Florian; Denz, Cornelia

    2012-08-01

    The Kramers-Moyal analysis is a well-established approach to analyze stochastic time series from complex systems. If the sampling interval of a measured time series is too low, systematic errors occur in the analysis results. These errors are labeled as finite time effects in the literature. In the present article, we present some new insights about these effects and discuss the limitations of a previously published method to estimate Kramers-Moyal coefficients at the presence of finite time effects. To increase the reliability of this method and to avoid misinterpretations, we extend it by the computation of error estimates for estimated parameters using a Monte Carlo error propagation technique. Finally, the extended method is applied to a data set of an optical trapping experiment yielding estimations of the forces acting on a Brownian particle trapped by optical tweezers. We find an increased Markov-Einstein time scale of the order of the relaxation time of the process, which can be traced back to memory effects caused by the interaction of the particle and the fluid. Above the Markov-Einstein time scale, the process can be very well described by the classical overdamped Markov model for Brownian motion.

  15. Extending Learning Communities: New Technologies, Multiple Literacies, and Culture Blind Pedagogies

    ERIC Educational Resources Information Center

    Knight, Michelle G.; Dixon, Iris R.; Norton, Nadjwa E. L.; Bentley, Courtney

    2004-01-01

    Technologies such as videoconferencing used for distance education are creating ways for high schools to extend their learning communities to connect youth with professional communities of practice in ways that approximate the face-to-face interactions in traditional classrooms. These technologies are often touted as a way to augment course…

  16. Organization, selection, and training of crews for extended spaceflight: findings from analogs and implications.

    PubMed

    Nicholas, J M; Foushee, H C

    1990-01-01

    Ample research evidence from space analogs points to the crucial role that teamwork plays in the performance of small groups in isolation and confinement. This paper surveys findings about the impacts of group behavior and social interaction on crew morale, coordination, and productivity. Implications for the organization, selection, and training of crews for extended spaceflight are discussed.

  17. Extended Gravity: State of the Art and Perspectives

    NASA Astrophysics Data System (ADS)

    Capozziello, Salvatore; de Laurentis, Mariafelicia

    2015-01-01

    Several issues coming from Cosmology, Astrophysics and Quantum Field Theory suggest to extend the General Relativity in order to overcome several shortcomings emerging at conceptual and experimental level. From one hand, standard Einstein theory fails as soon as one wants to achieve a full quantum description of space-time. In fact, the lack of a final self-consistent Quantum Gravity Theory can be considered one of the starting points for alternative theories of gravity. Specifically, the approach based on corrections and enlargements of the Einstein scheme, have become a sort of paradigm in the study of gravitational interaction. On the other hand, such theories have acquired great interest in cosmology since they "naturally" exhibit inflationary behaviours which can overcome the shortcomings of standard cosmology. From an astrophysical point of view, Extended Theories of Gravity do not require to find candidates for dark energy and dark matter at fundamental level; the approach starts from taking into account only the "observed" ingredients (i.e., gravity, radiation and baryonic matter); it is in full agreement with the early spirit of General Relativity but one has to relax the strong hypothesis that gravity acts at same way at all scales. Several scalar-tensor and f(R)-models agree with observed cosmology, extragalactic and galactic observations and Solar System tests, and give rise to new effects capable of explaining the observed acceleration of cosmic fluid and the missing matter effect of self-gravitating structures. Despite these preliminary results, no final model addressing all the open issues is available at the moment, however the paradigm seems promising in order to achieve a complete and self-consistent theory working coherently at all interaction scales.

  18. Implementing extended observing at the JCMT

    NASA Astrophysics Data System (ADS)

    Walther, Craig; Dempsey, Jessica; Campbell, Ian

    2014-08-01

    The James Clerk Maxwell Telescope (JCMT) is the largest single dish submillimetre telescope in the world. Recently the Joint Astronomy Centre (JAC) has learned that the JCMT will no longer receive financial support from its original supporting agencies after September 2014. There is significant pressure to complete some surveys that have been in progress at the JCMT for many years now. With the goal of completing a higher percentage of these surveys it was decided to take advantage of the hours between when the telescope operator leaves the telescope and when the day crew arrives. These hours generally have reasonable seeing and low column integrated water vapor, so they are good for observing. This observing is being performed remotely, in Hilo, without staff at the telescope, by staff members who do not have telescope operation as part of their job descriptions. This paper describes the hardware changes necessary to implement remote observing at JCMT. It also describes the software needed for remote, fail safe, operation of the telescope. The protocols and rules for passing the control of the telescope between the various groups are discussed. Since these Extended Operators are not expert telescope operators, the system was simplified as much as possible, but some training was necessary and proper checklists are essential. Due to the success of the first phase of Extending Observing at the JCMT, the hours when the weather is good and no one is at the telescope, but no day crew is on the way, are also now being utilized. Extended Observing has already yielded a considerable amount of science observing time.

  19. Extended quantification of the generalized recurrence plot

    NASA Astrophysics Data System (ADS)

    Riedl, Maik; Marwan, Norbert; Kurths, Jürgen

    2016-04-01

    The generalized recurrence plot is a modern tool for quantification of complex spatial patterns. Its application spans the analysis of trabecular bone structures, Turing structures, turbulent spatial plankton patterns, and fractals. But, it is also successfully applied to the description of spatio-temporal dynamics and the detection of regime shifts, such as in the complex Ginzburg-Landau- equation. The recurrence plot based determinism is a central measure in this framework quantifying the level of regularities in temporal and spatial structures. We extend this measure for the generalized recurrence plot considering additional operations of symmetry than the simple translation. It is tested not only on two-dimensional regular patterns and noise but also on complex spatial patterns reconstructing the parameter space of the complex Ginzburg-Landau-equation. The extended version of the determinism resulted in values which are consistent to the original recurrence plot approach. Furthermore, the proposed method allows a split of the determinism into parts which based on laminar and non-laminar regions of the two-dimensional pattern of the complex Ginzburg-Landau-equation. A comparison of these parts with a standard method of image classification, the co-occurrence matrix approach, shows differences especially in the description of patterns associated with turbulence. In that case, it seems that the extended version of the determinism allows a distinction of phase turbulence and defect turbulence by means of their spatial patterns. This ability of the proposed method promise new insights in other systems with turbulent dynamics coming from climatology, biology, ecology, and social sciences, for example.

  20. Extending the applicability of multigrid methods

    SciTech Connect

    Brannick, J; Brezina, M; Falgout, R; Manteuffel, T; McCormick, S; Ruge, J; Sheehan, B; Xu, J; Zikatanov, L

    2006-09-25

    Multigrid methods are ideal for solving the increasingly large-scale problems that arise in numerical simulations of physical phenomena because of their potential for computational costs and memory requirements that scale linearly with the degrees of freedom. Unfortunately, they have been historically limited by their applicability to elliptic-type problems and the need for special handling in their implementation. In this paper, we present an overview of several recent theoretical and algorithmic advances made by the TOPS multigrid partners and their collaborators in extending applicability of multigrid methods. Specific examples that are presented include quantum chromodynamics, radiation transport, and electromagnetics.

  1. Extended Criteria Donors in Liver Transplantation.

    PubMed

    Vodkin, Irine; Kuo, Alexander

    2017-05-01

    Mortality rates on the liver transplant waiting list are increasing. The shortage of organs has resulted in higher utilization of extended criteria donors (ECDs), with centers pushing the limits of what is acceptable for transplantation. Donor quality is more appropriately represented as a continuum of risk, and careful selection and matching of ECD grafts with recipients may lead to excellent outcomes. Although there is no precise definition for what constitutes an ECD liver, this review focuses on frequently cited characteristics, including donor age, steatosis, donation after cardiac death, and donors with increased risk of disease transmission.

  2. Extending quantum coherence of superconducting flux

    NASA Astrophysics Data System (ADS)

    Yan, Fei; Kamal, Archana; Orlando, Terry; Gustavsson, Simon; Oliver, William; Engineering Quantum Systems, MIT Team

    We present the design of a superconducting qubit with multiple Josephson junctions. The design starts with a capacitively shunted flux qubit, and it incorporates particular junction parameter choices for the purpose of simultaneously optimizing over transition frequency, anharmonicity, flux- and charge-noise sensitivity around flux degeneracy. By studying the scaling properties with design parameters, we identify directions to extend coherence substantially. This research was funded by the Office of the Director of National Intelligence (ODNI), Intelligence Advanced Research Projects Activity (IARPA) via MIT Lincoln Laboratory under Air Force Contract No. FA8721-05-C-0002.

  3. Extended HI disks in nearby spiral galaxies

    NASA Astrophysics Data System (ADS)

    Bosma, Albert

    2017-03-01

    In this short write-up, I will concentrate on a few topics of interest. In the 1970s I found very extended HI disks in galaxies such as NGC 5055 and NGC 2841, out to 2 - 2.5 times the Holmberg radius. Since these galaxies are warped, a ``tilted ring model'' allows rotation curves to be derived, and evidence for dark matter to be found. The evaluation of the amount of dark matter is hampered by a disk-halo degeneracy, which can possibly be broken by observations of velocity dispersions in both the MgI region and the CaII region.

  4. Extendable retractable telescopic mast for deployable structures

    NASA Technical Reports Server (NTRS)

    Schmid, M.; Aguirre, M.

    1986-01-01

    The Extendable and Retractable Mast (ERM) which is presently developed by Dornier in the frame of an ESA-contract, will be used to deploy and retract large foldable structures. The design is based on a telescopic carbon-fiber structure with high stiffness, strength and pointing accuracy. To verify the chosen design, a breadboard model of an ERM was built and tested under thermal vacuum (TV)-conditions. It is planned as a follow-on development to manufacture and test an Engineering Model Mast. The Engineering Model will be used to establish the basis for an ERM-family covering a wide range of requirements.

  5. Improving epidemic control strategies by extended detection

    NASA Astrophysics Data System (ADS)

    Karp, Paweł; Dybiec, Bartłomiej; Kleczkowski, Adam

    2014-11-01

    Majority of epidemics eradication programs work in preventive responsive way. The lack of exact information about epidemiological status of individuals makes responsive actions less efficient. Here, we demonstrate that additional tests can significantly increase the efficiency of "blind" treatment (vaccination or culling). Eradication strategy consisting of "blind" treatment in very limited local neighborhood supplemented by extra tests in a little bit larger neighborhood is able to prevent invasion of even highly infectious diseases and to achieve this at a cost lower than for the "blind" strategy. The effectiveness of the extended strategy depends on such parameters as the test efficiency and test cost.

  6. Extended Scaling Relations for Planar Lattice Models

    NASA Astrophysics Data System (ADS)

    Benfatto, G.; Falco, P.; Mastropietro, V.

    2009-12-01

    It is widely believed that the critical properties of several planar lattice systems, like the Eight Vertex or the Ashkin-Teller models, are well described by an effective continuum fermionic theory obtained as a formal scaling limit. On the basis of this assumption several extended scaling relations among their indices were conjectured. We prove the validity of some of them, among which the ones predicted by Kadanoff (Phys Rev Lett 39:903-905, 1977) and by Luther and Peschel (Phys Rev B 12:3908-3917, 1975).

  7. Primordial fluctuations in extended Liouville theory

    NASA Astrophysics Data System (ADS)

    Moore, Wynton E.

    Liouville gravity can be used to precisely model features of 3+1 dimensional cosmology in a simplified 1+1d setting. We study primordial fluctuations in a generally covariant extension of Liouville theory, in the context of single field inflation. The scale invariant spectrum of scalar curvature perturbations is exhibited, and their three-point correlation function is computed in the slow roll approximation. We recover Maldacena's consistency relation for the three-point function, which in this context depends on a global shift symmetry of extended Liouville theory.

  8. Primordial fluctuations in extended Liouville theory

    NASA Astrophysics Data System (ADS)

    Moore, Wynton E.

    2015-03-01

    Liouville gravity can be used to precisely model features of 3+1 dimensional cosmology in a simplified 1+1d setting. We study primordial fluctuations in a generally covariant extension of Liouville theory, in the context of single field inflation. The scale invariant spectrum of scalar curvature perturbations is exhibited, and their three-point correlation function is computed in the slow roll approximation. We recover Maldacena's consistency relation for the three-point function, which in this context depends on a global shift symmetry of extended Liouville theory.

  9. Extended-Spectrum Cephalosporinase in Acinetobacter baumannii▿

    PubMed Central

    Rodríguez-Martínez, José-Manuel; Nordmann, Patrice; Ronco, Esthel; Poirel, Laurent

    2010-01-01

    An AmpC-type β-lactamase conferring high-level resistance to expanded-spectrum cephalosporins and monobactams was characterized from an Acinetobacter baumannii clinical isolate. This class C β-lactamase (named ADC-33) possessed a Pro210Arg substitution together with a duplication of an Ala residue at position 215 (inside the Ω-loop) compared to a reference AmpC cephalosporinase from A. baumannii. ADC-33 hydrolyzed ceftazidime, cefepime, and aztreonam at high levels, which allows the classification of this enzyme as an extended-spectrum AmpC (ESAC). Site-directed mutagenesis confirmed the role of both substitutions in its ESAC property. PMID:20547808

  10. Simulating futures in extended common LISP

    NASA Technical Reports Server (NTRS)

    Nachtsheim, Philip R.

    1988-01-01

    Stack-groups comprise the mechanism underlying implementation of multiprocessing in Extended Common LISP, i.e., running multiple quasi-simultaneous processes within a single LISP address space. On the other hand, the future construct of MULTILISP, an extension of the LISP dialect scheme, deals with parallel execution. The source of concurrency that future exploits is the overlap between computation of a value and use of the value. Described is a simulation of the future construct by an interpreter utilizing stack-group extensions to common LISP.

  11. Proving refinement transformations using extended denotational semantics

    SciTech Connect

    Winter, V.L.; Boyle, J.M.

    1996-04-01

    TAMPR is a fully automatic transformation system based on syntactic rewrites. Our approach in a correctness proof is to map the transformation into an axiomatized mathematical domain where formal (and automated) reasoning can be performed. This mapping is accomplished via an extended denotational semantic paradigm. In this approach, the abstract notion of a program state is distributed between an environment function and a store function. Such a distribution introduces properties that go beyond the abstract state that is being modeled. The reasoning framework needs to be aware of these properties in order to successfully complete a correctness proof. This paper discusses some of our experiences in proving the correctness of TAMPR transformations.

  12. Resonance regions of extended Mathieu equation

    NASA Astrophysics Data System (ADS)

    Semyonov, V. P.; Timofeev, A. V.

    2016-02-01

    One of the mechanisms of energy transfer between degrees of freedom of dusty plasma system is based on parametric resonance. Initial stage of this process can de described by equation similar to Mathieu equation. Such equation is studied by analytical and numerical approach. The numerical solution of the extended Mathieu equation is obtained for a wide range of parameter values. Boundaries of resonance regions, growth rates of amplitudes and times of onset are obtained. The energy transfer between the degrees of freedom of dusty plasma system can occur over a wide range of frequencies.

  13. An extended micromechanics method for probing interphase properties in polymer nanocomposites [An extended micromechanics method for overlapping geometries with application to polymer nanocomposites

    SciTech Connect

    Liu, Zeliang; Moore, John A.; Liu, Wing Kam

    2016-05-03

    Inclusions comprised on filler particles and interphase regions commonly form complex morphologies in polymer nanocomposites. Addressing these morphologies as systems of overlapping simple shapes allows for the study of dilute particles, clustered particles, and interacting interphases all in one general modeling framework. To account for the material properties in these overlapping geometries, weighted-mean and additive overlapping conditions are introduced and the corresponding inclusion-wise integral equations are formulated. An extended micromechanics method based on these overlapping conditions for linear elastic and viscoelastic heterogeneous material is then developed. An important feature of the proposed approach is that the effect of both the geometric overlapping (clustered particles) and physical overlapping (interacting interphases) on the effective properties can be distinguished. Lastly, we apply the extended micromechanics method to a viscoelastic polymer nanocomposite with interphase regions, and estimate the properties and thickness of the interphase region based on experimental data for carbon-black filled styrene butadiene rubbers.

  14. The many faces of interaction.

    PubMed

    Reynolds, P A; Mason, R; Harper, J

    2008-05-24

    During the process of learning teachers and/or students interact with each other on a personal level. However, in e-learning the process is achieved through the intermediary of an information and communication technology (ICT) system or service. Descriptions of these ICT-human interface devices are given in this paper. Successful interaction depends not just on personal relationships, but also on understanding and the ability to use computers and communications equipment effectively. Interactivity, when using ICT, may as a result be different from that in a traditional classroom. The computer is the main man-machine interface and modulates people's ability to interact. Newer, mobile technology will extend the ability to interact in terms of time and place, as is illustrated by the use of portable digital assistants for dental teaching in clinics. The paper concludes that it is very important that both teachers and students should understand how to interact optimally with current and future ICT systems and devices.

  15. Engineering extended Hubbard models with Zeeman excitations of ultracold Dy atoms

    NASA Astrophysics Data System (ADS)

    Vargas-Hernández, R. A.; Krems, R. V.

    2016-12-01

    We show that Zeeman excitations of ultracold Dy atoms trapped in an optical lattice can be used to engineer extended Hubbard models with tunable inter-site and particle number-non-conserving interactions. We show that the ratio of the hopping amplitude and inter-site interactions in these lattice models can be tuned in a wide range by transferring the atoms to different Zeeman states. We propose to use the resulting controllable models for the study of the effects of direct particle interactions and particle number-non-conserving terms on Anderson localization.

  16. Thermodynamic study of the binding of calcium and magnesium ions with myelin basic protein using the extended solvation theory.

    PubMed

    Behbehani, G Rezaei; Saboury, A A; Divsalar, A

    2008-11-01

    The interaction of myelin basic protein (MBP) from the bovine central nervous system with Ca2+ and Mg2+ ions, named as M2+, was studied by isothermal titration calorimetry at 27 degrees C in aqueous solution. The extended solvation model was used to reproduce the enthalpies of MBP+M2+ interactions. The solvation parameters recovered from the extended solvation model were attributed to the structural change of MBP due to the metal ion interaction. It was found that there is a set of two identical and noninteracting binding sites for Ca2+ and Mg2+ ions.

  17. Extending problem-solving procedures through reflection.

    PubMed

    Anderson, John R; Fincham, Jon M

    2014-11-01

    A large-sample (n=75) fMRI study guided the development of a theory of how people extend their problem-solving procedures by reflecting on them. Both children and adults were trained on a new mathematical procedure and then were challenged with novel problems that required them to change and extend their procedure to solve these problems. The fMRI data were analyzed using a combination of hidden Markov models (HMMs) and multi-voxel pattern analysis (MVPA). This HMM-MVPA analysis revealed the existence of 4 stages: Encoding, Planning, Solving, and Responding. Using this analysis as a guide, an ACT-R model was developed that improved the performance of the HMM-MVPA and explained the variation in the durations of the stages across 128 different problems. The model assumes that participants can reflect on declarative representations of the steps of their problem-solving procedures. A Metacognitive module can hold these steps, modify them, create new declarative steps, and rehearse them. The Metacognitive module is associated with activity in the rostrolateral prefrontal cortex (RLPFC). The ACT-R model predicts the activity in the RLPFC and other regions associated with its other cognitive modules (e.g., vision, retrieval). Differences between children and adults seemed related to differences in background knowledge and computational fluency, but not to the differences in their capability to modify procedures.

  18. Extended life aluminide fuel. Final report

    SciTech Connect

    Miller, L.G.; Beeston, J.M.

    1986-06-01

    As the price of fuel fabrication, shipment of both new and spent fuel, and fuel reprocessing continue to rise at a rapid rate, researchers look for alternate methods to keep reactor fuel costs within their limited funding. Extended fuel element lifetimes, without jeopardizing reactor safety, can reduce fuel costs by up to a factor of two. The Extended Life Aluminide (ELAF) program was started at the Idaho National Engineering Laboratory (INEL) as a joint project of the United States Department of Energy (DOE), the University of Missouri, and the Massachusetts Institute of Technology research reactors. Fuel plates of Advanced Test Reactor (ATR) type construction were fabricated at Atomics International and irradiated in the ATR at the INEL. Four fuel matrix compositions were tested (i.e., 50 vol% UAl/sub x/ cores for reference, and 40, 45 and 50 vol% UAl/sub 2/ cores). The 50 vol% UAl/sub 2/ cores contained up to 3 grams U-235 per cm/sup 3/ of core. Three plates of each composition were irradiated to peak burnup levels of 3 x 10/sup 21/ fission/cm/sup 3/ of core. The only observed damage was due to external corrosion at similar rates experienced by UAl/sub x/ fuel elements in test reactors.

  19. Spatially Extended Memory Models of Cardiac Tissue

    NASA Astrophysics Data System (ADS)

    Fox, Jeffrey; Riccio, Mark; Hua, Fei; Bodenschatz, Eberhard; Gilmour, Robert

    2002-03-01

    Beat-to-beat alternation of cardiac electrical properties (alternans) commonly occurs during rapid periodic pacing. Although alternans is generally associated with a resititution curve with slope >=1, recent studies by Gauthier and co-workers reported the absence of alternans in frog heart tissue with a restitution curve of slope >=1. These experimental findings were understood in terms of a memory model in which the duration D of an action potential depends on the preceding rest interval I as well as a memory variable M that accumulates during D and dissipates during I. We study the spatiotemporal dynamics of a spatially extended 1-d fiber using an ionic model that exhibits memory effects. We find that while a single cell can have a restitution slope >=1 and not show alternans (because of memory), the spatially extended system exhibits alternans. To understand the dynamical mechanism of this behavior, we study a coupled maps memory model both numerically and analytically. These results illustrate that spatial effects and memory effects can play a significant role in determining the dynamics of wave propagation in cardiac tissue.

  20. Pumpdown assistance extends coiled tubing reach

    SciTech Connect

    Tailby, R.J. )

    1992-07-01

    One of the most challenging coiled tubing applications to emerge in the last few years is horizontal well maintenance. When wireline cannot be used, techniques that offer some of the same flexibility, availability and relatively low cost must be used. During this same period, however, drilling technology has also made huge strides in horizontal and extended-reach areas. Wells are now being drilled with horizontal lengths in excess of 6,000 ft and measured depths of more than 22,000 ft. This paper reports that although horizontal wells are definitely here to stay, many operators have had to reevaluate their positions after being confronted with the problem of recompleting these wells to eliminate excessive water or gas production. A full workover with workstring using either a drilling rig or snubbing unit can be expensive and may lead to lost production because of limited rig availability. Coiled tubing has successfully been used in most cases thus far, but it has length and horizontal reach limitations that drilling technology will soon overtake. Within the constraints of current technology and tube capabilities, coiled tubing does not have the buckling resistance or reel capacity to service today's longest horizontal and extended reach wells or those planned and foreseen in the future. Even if coiled tubing can reach TD, operations requiring downward force are severely restricted.

  1. Medical planning for extended remote expeditions.

    PubMed

    Iserson, Kenneth V

    2013-12-01

    Remote extended expeditions often support scientific research and commercial resource exploration or extraction in hostile environments. Medical support for these expeditions is inherently complex and requires in-depth planning. To be successful, this planning must include substantial input from clinicians with experience in remote, emergency, and prehospital medicine and from personnel familiar with the proposed working environment. Using the guidelines discussed in this paper will help ensure that planners consider all necessary, medically relevant elements before launching an extended remote expedition. The 10 key elements of a workable remote healthcare system are to: 1. Optimize workers’ fitness. 2. Anticipate treatable problems. 3. Stock appropriate medications. 4. Provide appropriate equipment. 5. Provide adequate logistical support. 6. Provide adequate medical communications. 7. Know the environmental limitations on patient access and evacuation. 8. Use qualified providers. 9. Arrange for knowledgeable and timely consultations. 10. Establish and distribute rational administrative rules. Planners using these guidelines may better be able to generate a strategy that optimizes the participants' health benefits, the expedition's productivity, and the expedition sponsor's cost savings.

  2. NASA's extended duration orbiter medical program

    NASA Technical Reports Server (NTRS)

    Pool, Sam Lee; Sawin, Charles F.

    1992-01-01

    The physiological issues involved in safely extending Shuttle flights from 10 to 16 days have been viewed by some as academic. After all, they reasoned, humans already have lived and worked in space for periods exceeding even 28 days in the United States Skylab Program and onboard the Russian space stations. The difference in the Shuttle program is in the physical position of the astronauts as they reenter the Earth's atmosphere. Crewmembers in the earlier Apollo, Skylab, and Russian programs were returned to Earth in the supine position. Space Shuttle crewmembers, in contrast, are seated upright during reentry and landing; reexperiencing the Earth's g forces in this position has far more pronounced effects on the crewmember's physiological functions. The goal of the Extended Duration Orbiter (EDO) Medical Project (EDOMP) has been to ensure that crewmembers maintain physiological reserves sufficient to perform entry, landing, and egress safely. Early in the Shuttle Program, it became clear that physiological deconditioning during space flight could produce significant symptoms upon return to Earth. The signs and symptoms observed during the entry, landing, and egress after Shuttle missions have included very high heart rates and low blood pressures upon standing. Dizziness, 'graying out,' and fainting have occurred on ambulation or shortly thereafter. Other symptoms at landing have included headache, light-headedness, nausea and vomitting, leg cramping, inability to stand for several minutes after wheel-stop, and unsteadiness of gait.

  3. Agents in grid extended to clouds

    NASA Astrophysics Data System (ADS)

    Wasielewska, K.; Ganzha, M.; Paprzycki, M.; Bǎdicǎ, C.; Ivanovic, M.; Lirkov, I.; Fidanova, S.

    2016-10-01

    The presented work is an attempt to extend considerations from the Agents in Grid (AiG) project to the Clouds. The AiG project is aimed at the development of an agent-semantic infrastructure for efficient resource management in the grid. Decision support within the AIG system helps the user, without in-depth knowledge, to choose optimal algorithm and/or resource to solve a problem from a given domain, and later to choose the best contract defining terms of collaboration with the provider of a resource used to solve the problem. Cloud computing refers to an architecture, in which groups of remote servers are networked, to allow online access to computer services or resources. The general vision is the same as in the case of computational grids, i.e., to reduce cost of computing, as well as to increase flexibility and reliability of the infrastructure. However, there are also important differences. It is relatively easy to notice that solutions considered in the context of the AiG system can be easily extended to computational clouds that evolved from computational grids. As it was shown in the case of grids, integrating software agents, semantics and cloud computing could enable highly efficient, intelligent systems, making clouds even more flexible, autonomic and usable.

  4. Silicon drift chamber with extended energy range

    NASA Astrophysics Data System (ADS)

    Labanti, Claudio; Dal Fiume, Daniele; Fiorini, Carlo; Longoni, Antonio; Mauri, Alessandro; Perotti, Francesco; Rossi, Elio; Stephen, John B.

    2000-12-01

    The requirement for future X-ray Astronomy instrumentation to exhibit a combination of good energy resolution and an extended energy range may be fulfilled by the development of a X ray detectors made from coupling a Silicon Drift Chamber (SDC), to a scintillation crystal. We report on such a detector made with an SDC of 3 mm diameter and using a Caesium Iodide [CsI(Tl)] scintillator. The radiation input window is located on the Si side of the assembly so than soft X-rays are directly detected by the SDC. This allows a minimum threshold of about 1 keV at 0 degrees Celsius to be obtained. The Silicon Drift Chamber acts also as a photodiode able to detect the scintillation light produced by the CsI(Tl), thus extending the energy range of such a device up to some MeV. The discrimination of events between these two detection layers is performed by using a pulse shape discriminator in order to differentiate between the different rise times of the collected charge. The detector concept is discussed on the basis of the results already achieved and the future developments foreseen.

  5. Applying SPAM to the extended MWA

    NASA Astrophysics Data System (ADS)

    Hurley-Walker, N.; Intema, H.

    2017-01-01

    The extended baselines of the MWA move the instrument into a more difficult calibration and imaging regime, where the more widely-separated antennas are more likely to view the sky through different ionospheric conditions, leading to differential refractive effects over the array. Current extrapolations by Trott, Jordan, and Hurley-Walker imply that the diffractive scale will remain larger than the longest baseline for 50-70% of observations, but these are extrapolations only. Other instruments have performed observations with baselines longer than the diffractive scale, and used software techniques to mitigate the ionospheric distortions. One such survey is the Tata Institute of Fundamental Research Giant Metrewave Radio Telescope Sky Survey (TGSS) at 150 MHz. Intema et al. (2016) used the Source Peeling & Atmospheric Modeling (SPAM) software to produce a catalogue of over 600,000 sources from data that had previously been slow and difficult to process. This proposal is for a short series of observations to test the usage of the SPAM software on the extended MWA, and to find the optimal observing parameters for its use. If successful, this could assist other groups in effectively utilising the long baselines.

  6. Extending U.S. Medicare to Mexico

    PubMed Central

    Haims, Marla C.; Dick, Andrew W.

    2012-01-01

    Abstract There is a lack of hard data on the exact number of Medicare-eligible retirees residing in Mexico, but it is at least in the tens of thousands and is certainly rising as the baby boom generation reaches retirement. Because Medicare does not cover health services received outside the United States, these retirees must travel to the United States for health care or purchase alternative coverage for health services received in Mexico. There are several arguments for extending Medicare to Mexico—that is, allowing Medicare-eligible beneficiaries to receive their Medicare benefits in Mexico. Medicare-eligible retirees living in Mexico would certainly benefit, and Mexico might benefit from improved quality of care and an expanded health economy. Moreover, American taxpayers might benefit from a reduced total cost of Medicare: To the extent that extending Medicare to Mexico induces Medicare beneficiaries to substitute higher-cost U.S. health care services with lower-cost Mexican services, overall Medicare expenditures might be reduced. The authors outline four options for how this policy change might be implemented and describe a conceptual model that could be used to assess the effects of each option. PMID:28083264

  7. An extended synthesis for evolutionary biology.

    PubMed

    Pigliucci, Massimo

    2009-06-01

    Evolutionary theory is undergoing an intense period of discussion and reevaluation. This, contrary to the misleading claims of creationists and other pseudoscientists, is no harbinger of a crisis but rather the opposite: the field is expanding dramatically in terms of both empirical discoveries and new ideas. In this essay I briefly trace the conceptual history of evolutionary theory from Darwinism to neo-Darwinism, and from the Modern Synthesis to what I refer to as the Extended Synthesis, a more inclusive conceptual framework containing among others evo-devo, an expanded theory of heredity, elements of complexity theory, ideas about evolvability, and a reevaluation of levels of selection. I argue that evolutionary biology has never seen a paradigm shift, in the philosophical sense of the term, except when it moved from natural theology to empirical science in the middle of the 19th century. The Extended Synthesis, accordingly, is an expansion of the Modern Synthesis of the 1930s and 1940s, and one that--like its predecessor--will probably take decades to complete.

  8. Fundamentals of Physics, Extended 7th Edition

    NASA Astrophysics Data System (ADS)

    Halliday, David; Resnick, Robert; Walker, Jearl

    2004-05-01

    No other book on the market today can match the 30-year success of Halliday, Resnick and Walker's Fundamentals of Physics! Fundamentals of Physics, 7th Edition and the Extended Version, 7th Edition offer a solid understanding of fundamental physics concepts, helping readers apply this conceptual understanding to quantitative problem solving, in a breezy, easy-to-understand style. A unique combination of authoritative content and stimulating applications. * Numerous improvements in the text, based on feedback from the many users of the sixth edition (both instructors and students) * Several thousand end-of-chapter problems have been rewritten to streamline both the presentations and answers * 'Chapter Puzzlers' open each chapter with an intriguing application or question that is explained or answered in the chapter * Problem-solving tactics are provided to help beginning Physics students solve problems and avoid common error * The first section in every chapter introduces the subject of the chapter by asking and answering, "What is Physics?" as the question pertains to the chapter * Numerous supplements available to aid teachers and students The extended edition provides coverage of developments in Physics in the last 100 years, including: Einstein and Relativity, Bohr and others and Quantum Theory, and the more recent theoretical developments like String Theory.

  9. Extended Solar System Structures Observed by WISE

    NASA Astrophysics Data System (ADS)

    Sykes, Mark V.; Masci, Frank; Cutri, Roc; Walker, Russell; Mainzer, Amy; Bauer, James; Stevenson, Rachel; Tricarico, Pasquale

    2014-11-01

    Extended structures associated with recent asteroid collisions and comets were detected by the Infrared Astronomical Satellite, which conducted the first survey of the thermal emission of the sky in 1983. Twenty-seven years later, the Wide-field Infrared Survey Explorer (WISE), conducted a more sensitive survey of the sky at wavelengths spanning the shorter IRAS bandpasses and detected many of these same structures. Initial identifications include asteroid dust bands associated with collisions giving rise to the Karin and Beagle clusters within the Koronis and Themis asteroid families, respectively. An additional pair of bands is associated with the collision giving rise to the Veritas asteroid family. Comet trails associated with short-period comets have also been observed. Type 2 trails, detected by IRAS and possibly associated with asteroid collisions within the past few thousand years, have yet to be identified. Because WISE is significantly more sensitive than IRAS in the mid-infrared, it has detected some trails extending much further over their orbits and will greatly expand the catalog of trails detected in addition to those observed by IRAS and Spitzer (the latter by targeted observations). WISE and the yet more sensitive NEOCAM survey telescope will provide important insights into the recent collisional history of the asteroid belt and the nature and evolution of comets.

  10. Screw-Shaped Light in Extended Electromagnetics

    NASA Astrophysics Data System (ADS)

    Lehnert, B.

    2005-01-01

    Twisted light beams have recently been observed for which the energy travels in a corkscrew-shaped path, spiralling around the beam's central axis. These discoveries are expected to become important to the development of new methods in the field of communication, as well as to the invention of new tools in microbiology. In this paper is shown that conventional theory based on Maxwell's equations cannot explain the basic features of twisted light. On the other hand an extended electromagnetic theory, based on a nonzero electric field divergence in the vacuum state, appears to be reconcilable with the main behaviour of the twisted light phenomena. The solutions and the set of modes being obtained from this extended theory are applicable both to models of high and low density photon beams and to those of individual photons, all having limited extensions in space and possessing an angular momentum (spin). Thereby beam models can be developed the intensity of which forms a ring-shaped cross-section, and individual photon models can be obtained which have the features of "needle radiation". However, within the limits of validity of the approximations made so far in the analysis, it is not clear whether the effective diameter of the individual photon models can be small enough to approach atomic dimensions.

  11. Planet Hunters in the Kepler Extended Mission

    NASA Astrophysics Data System (ADS)

    Schwamb, Megan E.; Lintott, C. J.; Fischer, D.; Brewer, J. M.; Giguere, M. J.; Lynn, S.; Parrish, M.; Schawinski, K.; Simpson, R.; Smith, A. M.; Orosz, J. A.; Carter, J. A.; Howard, A.; Torres, G.; Crepp, J. R.; Keel, W. C.; Welsh, W. F.; Kaib, N. A.; Terrell, D.; Gagliano, R.; Jek, K. J.

    2013-01-01

    Planet Hunters (http://www.planethunters.org), part of the Zooniverse's (http://www.zooniverse.org) collection of online citizen science projects, uses the World Wide Web to enlist the general public to identify transits in the Kepler light curves. Volunteers are asked to draw boxes to mark the locations of visible transits, with multiple independent classifiers reviewing a randomly selected ~30-day light curve segment from one of Kepler's ~160,000 target stars. Since December 2010, more than 170,000 members of the general public have participated in Planet Hunters contributing over 13 million classifications. With the start of the Kepler extended mission, Planet Hunters has entered a new phase. We will detail the upgrades and new features added to the project, highlighting in particular our search for circumbinary planets (planets orbiting both stars in binary) in the the extended mission Quarterly data releases. We will also report on our latest planet candidates, including the characterization of our first confirmed planet candidate, a circumbinary planet in a four star system. Acknowledgements: MES is supported by a National Science Foundation Astronomy and Astrophysics Postdoctoral Fellowship under award AST-1003258 and in part by an American Philosophical Society Franklin Grant.

  12. Thermoplastic Polyurethanes with Isosorbide Chain Extender

    SciTech Connect

    Javni, Ivan; Bilic, Olivera; Bilic, Nikola; Petrovic, Zoran; Eastwood, Eric; Zhang, Fan; Ilavsky, Jan

    2015-12-15

    Isosorbide, a renewable diol derived from starch, was used alone or in combination with butane diol (BD) as the chain extender in two series of thermoplastic polyurethanes (TPU) with 50 and 70% polytetramethylene ether glycol (PTMEG) soft segment concentration (SSC), respectively. In the synthesized TPUs, the hard segment composition was systematically varied in both series following BD/isosorbide molar ratios of 100 : 0; 75 : 25; 50 : 50; 25 : 75, and 0 : 100 to examine in detail the effect of chain extenders on properties of segmented polyurethane elastomers with different morphologies. We found that polyurethanes with 50% SSC were hard elastomers with Shore D hardness of around 50, which is consistent with assumed co-continuous morphology. Polymers with 70% SSC displayed lower Shore A hardness of 74–79 (Shore D around 25) as a result of globular hard domains dispersed in the soft matrix. Insertion of isosorbide increased rigidity, melting point and glass transition temperature of hard segments and tensile strength of elastomers with 50% SSC. These effects were weaker or non-existent in 70% SSC series due to the short hard segments and low content of isosorbide. We also found that the thermal stability was lowered by increasing isosorbide content in both series.

  13. Choice mechanisms for past, temporally extended outcomes

    PubMed Central

    Vestergaard, Martin D.; Schultz, Wolfram

    2015-01-01

    Accurate retrospection is critical in many decision scenarios ranging from investment banking to hedonic psychology. A notoriously difficult case is to integrate previously perceived values over the duration of an experience. Failure in retrospective evaluation leads to suboptimal outcome when previous experiences are under consideration for revisit. A biologically plausible mechanism underlying evaluation of temporally extended outcomes is leaky integration of evidence. The leaky integrator favours positive temporal contrasts, in turn leading to undue emphasis on recency. To investigate choice mechanisms underlying suboptimal outcome based on retrospective evaluation, we used computational and behavioural techniques to model choice between perceived extended outcomes with different temporal profiles. Second-price auctions served to establish the perceived values of virtual coins offered sequentially to humans in a rapid monetary gambling task. Results show that lesser-valued options involving successive growth were systematically preferred to better options with declining temporal profiles. The disadvantageous inclination towards persistent growth was mitigated in some individuals in whom a longer time constant of the leaky integrator resulted in fewer violations of dominance. These results demonstrate how focusing on immediate gains is less beneficial than considering longer perspectives. PMID:26063841

  14. Thermodynamic products in extended phase-space

    NASA Astrophysics Data System (ADS)

    Pradhan, Parthapratim

    We have examined the thermodynamic properties for a variety of spherically symmetric charged-AdS black hole (BH) solutions, including the charged AdS BH surrounded by quintessence dark energy and charged AdS BH in f(R) gravity in extended phase-space. This framework involves treating the cosmological constant as thermodynamic variable (for example: thermodynamic pressure and thermodynamic volume). Then they should behave as an analog of Van-der-Waal (VdW) like systems. In the extended phase-space we have calculated the entropy product and thermodynamic volume product of all horizons. The mass (or enthalpy) independent nature of the said product signals they are universal quantities. The divergence of the specific heat indicates that the second-order phase transition occurs under certain condition. In Appendix A, we have studied the thermodynamic volume products for axisymmetric spacetime and it is shown to be not universal in nature. Finally, in Appendix B, we have studied the P ‑ V criticality of Cauchy horizon for charged-AdS BH and found to be an universal relation of critical values between two horizons as Pc‑ = P c+, vc‑ = v c+, Tc‑ = ‑T c+, ρc‑ = ‑ρ c+. The symbols are defined in the main work.

  15. Muon production in extended air shower simulations.

    PubMed

    Pierog, T; Werner, K

    2008-10-24

    Whereas air shower simulations are very valuable tools for interpreting cosmic ray data, there is a long-standing problem: it is difficult to accommodate at the same time the longitudinal development of air showers and the number of muons measured on the ground. Using a new hadronic interaction model (EPOS) in air shower simulations produces much more muons, in agreement with results from the HiRes-MIA experiment. We find that this is mainly due to a better description of (anti) baryon production in hadronic interactions. This is an aspect of air shower physics which has been neglected so far.

  16. Extended Glauber Model of Antiproton-Nucleus Annihilation for All Energies and Mass Numbers

    SciTech Connect

    Lee, Teck-Ghee; Wong, Cheuk-Yin

    2014-01-01

    Previous analytical formulas in the Glauber model for high-energy nucleus-nucleus collisions developed by Wong are utilized and extended to study Antiproton-nucleus annihilations for both high and low energies, after taking into account the effects of Coulomb and nuclear interactions, and the change of the antiproton momentum inside a nucleus. The extended analytical formulas capture the main features of the experimental antiproton-nucleus annihilation cross sections for all energies and mass numbers. At high antiproton energies, they exhibit the granular property for the lightest nuclei and the black-disk limit for the heavy nuclei. At low antiproton energies, they display the effect of the antiproton momentum increase due to the nuclear interaction for the light nuclei, and the effect of the magnification due to the attractive Coulomb interaction for the heavy nuclei.

  17. Intrinsic chemical sensor fibers for extended-length chlorine detection

    NASA Astrophysics Data System (ADS)

    Cordero, Steven R.; Ruiz, David; Huang, Weijie; Cohen, Leonard G.; Lieberman, Robert A.

    2004-12-01

    A fiber optic chlorine sensor having its entire length as the sensing element is reported here. The fiber consists of a silica core and a chlorine-sensitive cladding. Upon exposure to chlorine, the cladding very rapidly changes color resulting in attenuation of the light throughput of the fiber. A two-meter portion of sensor fiber responds to 10-ppm chlorine in milliseconds and to 1 ppm in several seconds. Furthermore, response to 100 ppb chlorine is realized in minutes. The high sensitivity suggests that the propagating modes of the light interact strongly with the cladding, and that these interactions are massively increased (Beers Law) due to the extended sensor length. The sensitivity to 1 ppm chlorine gas as a function of the length of fiber exposed between 0.3-30 meters is presented. The sensitivity to concentrations of chlorine from 0.1ppm-10ppm has been determined for a fixed 2 meter length of fiber. Pre-exposure fiber attenuation measures 70 dB/km (@ 633 nm) making it possible to detect chlorine on a continuous length of fiber on the scale of one hundred meters or more using standard detection methods (e.g. laser and photodetectors). This will replace the need of having a collection of point-detectors to cover large areas.

  18. Self-forces on extended bodies in electrodynamics

    SciTech Connect

    Harte, Abraham I.

    2006-03-15

    In this paper, we study the bulk motion of a classical extended charge in flat spacetime. A formalism developed by W. G. Dixon is used to determine how the details of such a particle's internal structure influence its equations of motion. We place essentially no restrictions (other than boundedness) on the shape of the charge, and allow for inhomogeneity, internal currents, elasticity, and spin. Even if the angular momentum remains small, many such systems are found to be affected by large self-interaction effects beyond the standard Lorentz-Dirac force. These are particularly significant if the particle's charge density fails to be much greater than its 3-current density (or vice versa) in the center-of-mass frame. Additional terms also arise in the equations of motion if the dipole moment is too large, and when the 'center-of-electromagnetic mass' is far from the 'center-of-bare mass' (roughly speaking). These conditions are often quite restrictive. General equations of motion were also derived under the assumption that the particle can only interact with the radiative component of its self-field. These are much simpler than the equations derived using the full retarded self-field; as are the conditions required to recover the Lorentz-Dirac equation.

  19. Ultraviolet spectroscopy of the extended solar corona

    NASA Astrophysics Data System (ADS)

    Kohl, John L.; Noci, Giancarlo; Cranmer, Steven R.; Raymond, John C.

    2006-04-01

    The first observations of ultraviolet spectral line profiles and intensities from the extended solar corona (i.e., more than 1.5 solar radii from Sun-center) were obtained on 13 April 1979 when a rocket-borne ultraviolet coronagraph spectrometer of the Harvard-Smithsonian Center for Astrophysics made direct measurements of proton kinetic temperatures, and obtained upper limits on outflow velocities in a quiet coronal region and a polar coronal hole. Following those observations, ultraviolet coronagraphic spectroscopy has expanded to include observations of over 60 spectral lines in coronal holes, streamers, coronal jets, and solar flare/coronal mass ejection (CME) events. Spectroscopic diagnostic techniques have been developed to determine proton, electron and ion kinetic temperatures and velocity distributions, proton and ion bulk flow speeds and chemical abundances. The observations have been made during three sounding rocket flights, four Shuttle deployed and retrieved Spartan 201 flights, and the Solar and Heliospheric Observatory (SOHO) mission. Ultraviolet spectroscopy of the extended solar corona has led to fundamentally new views of the acceleration regions of the solar wind and CMEs. Observations with the Ultraviolet Coronagraph Spectrometer (UVCS) on SOHO revealed surprisingly large temperatures, outflow speeds, and velocity distribution anisotropies in coronal holes, especially for minor ions. Those measurements have guided theorists to discard some candidate physical processes of solar wind acceleration and to increase and expand investigations of ion cyclotron resonance and related processes. Analyses of UVCS observations of CME plasma properties and the evolution of CMEs have provided the following: temperatures, inflow velocities and derived values of resistivity and reconnection rates in CME current sheets, compression ratios and extremely high ion temperatures behind CME shocks, and three dimensional flow velocities and magnetic field chirality in

  20. PREFACE: Complex Dynamics in Spatially Extended Systems

    NASA Astrophysics Data System (ADS)

    Mosekilde, Erik; Bohr, Tomas; Rasmussen, Jens Juul; Leth Christiansen, Peter

    1996-01-01

    Self-organization, or the spontaneous emergence of patterns and structures under far-from-equilibrium conditions, turbulence, and related nonlinear dynamic phenomena in spatially extended systems have developed into one of the most exciting topics of modern science. Phenomena of this type arise in a wide variety of different fields, ranging from the development of chemical and biological patterns in reaction-diffusion systems over vortex formation in connection with chemical, optical, hydrodynamic or magnetohydrodynamic turbulence to technical applications in connection with liquid crystal displays or pulse compression in optical communication systems. Lasers often show interesting patterns produced by self-focusing and other nonlinear phenomena, diffusion limited aggregation is known to generate fractal-like structures, and amazing struc- tures also arise in bacterial growth processes or when a droplet of an oil suspension of finely divided magnetic particles is subject to a magnetic field perpendicular to the surface of the cell in which it is contained. In September 1995 the Niels Bohr Institute in Copenhagen was the venue of an International Conference on Complex Dynamics in Spatially Extended Systems. Organizers of the conference were the three Danish centers for nonlinear dynamics: The Center for Chaos and Turbulence Studies (CATS), located at the Niels Bohr Institute; the Center for Modeling, Nonlinear Dynamics and Irreversible Thermodynamics (MIDIT), located at the Technical University of Denmark, and the Center for Nonlinear Dynamics in Continuum Systems, located at the Risø National Laboratories. In the spirit of the successful NATO Advanced Research Workshops on Spatiotemporal Patterns in Nonequilibrium Systems of which the last was held in Santa Fe, New Mexico in 1993, the conference aimed at stimulating new ideas and providing a forum for the exchange of knowledge between leading practitioners of the field. With its 50 invited speakers and more than

  1. Ongoing Mars Missions: Extended Mission Plans

    NASA Astrophysics Data System (ADS)

    Zurek, Richard; Diniega, Serina; Crisp, Joy; Fraeman, Abigail; Golombek, Matt; Jakosky, Bruce; Plaut, Jeff; Senske, David A.; Tamppari, Leslie; Thompson, Thomas W.; Vasavada, Ashwin R.

    2016-10-01

    Many key scientific discoveries in planetary science have been made during extended missions. This is certainly true for the Mars missions both in orbit and on the planet's surface. Every two years, ongoing NASA planetary missions propose investigations for the next two years. This year, as part of the 2016 Planetary Sciences Division (PSD) Mission Senior Review, the Mars Odyssey (ODY) orbiter project submitted a proposal for its 7th extended mission, the Mars Exploration Rover (MER-B) Opportunity submitted for its 10th, the Mars Reconnaissance Orbiter (MRO) for its 4th, and the Mars Science Laboratory (MSL) Curiosity rover and the Mars Atmosphere and Volatile Evolution (MVN) orbiter for their 2nd extended missions, respectively. Continued US participation in the ongoing Mars Express Mission (MEX) was also proposed. These missions arrived at Mars in 2001, 2004, 2006, 2012, 2014, and 2003, respectively. Highlights of proposed activities include systematic observations of the surface and atmosphere in twilight (early morning and late evening), building on a 13-year record of global mapping (ODY); exploration of a crater rim gully and interior of Endeavour Crater, while continuing to test what can and cannot be seen from orbit (MER-B); refocused observations of ancient aqueous deposits and polar cap interiors, while adding a 6th Mars year of change detection in the atmosphere and the surface (MRO); exploration and sampling by a rover of mineralogically diverse strata of Mt. Sharp and of atmospheric methane in Gale Crater (MSL); and further characterization of atmospheric escape under different solar conditions (MVN). As proposed, these activities follow up on previous discoveries (e.g., recurring slope lineae, habitable environments), while expanding spatial and temporal coverage to guide new detailed observations. An independent review panel evaluated these proposals, met with project representatives in May, and made recommendations to NASA in June 2016. In this

  2. Low-momentum NN interactions and all-order summation of ring diagrams of symmetric nuclear matter

    NASA Astrophysics Data System (ADS)

    Siu, L.-W.; Holt, J. W.; Kuo, T. T. S.; Brown, G. E.

    2009-05-01

    We study the equation of state for symmetric nuclear matter using a ring-diagram approach in which the particle-particle hole-hole (pphh) ring diagrams within a momentum model space of decimation scale Λ are summed to all orders. The calculation is carried out using the renormalized low-momentum nucleon-nucleon (NN) interaction Vlow-k, which is obtained from a bare NN potential by integrating out the high-momentum components beyond Λ. The bare NN potentials of CD-Bonn, Nijmegen, and Idaho have been employed. The choice of Λ and its influence on the single particle spectrum are discussed. Ring-diagram correlations at intermediate momenta (k≃2fm-1) are found to be particularly important for nuclear saturation, suggesting the necessity of using a sufficiently large decimation scale so that the above momentum region is not integrated out. Using Vlow-k with Λ~3fm-1, we perform a ring-diagram computation with the above potentials, which all yield saturation energies E/A and Fermi momenta kF(0) considerably larger than the empirical values. On the other hand, similar computations with the medium-dependent Brown-Rho scaled NN potentials give satisfactory results of E/A≃-15 MeV and kF(0)≃1.4fm-1. The effect of this medium dependence is well reproduced by an empirical three-body force of the Skyrme type.

  3. Affordances and the musically extended mind

    PubMed Central

    Krueger, Joel

    2014-01-01

    I defend a model of the musically extended mind. I consider how acts of “musicking” grant access to novel emotional experiences otherwise inaccessible. First, I discuss the idea of “musical affordances” and specify both what musical affordances are and how they invite different forms of entrainment. Next, I argue that musical affordances – via soliciting different forms of entrainment – enhance the functionality of various endogenous, emotion-granting regulative processes, drawing novel experiences out of us with an expanded complexity and phenomenal character. I argue that music therefore ought to be thought of as part of the vehicle needed to realize these emotional experiences. I appeal to different sources of empirical work to develop this idea. PMID:24432008

  4. Extendability of parallel sections in vector bundles

    NASA Astrophysics Data System (ADS)

    Kirschner, Tim

    2016-01-01

    I address the following question: Given a differentiable manifold M, what are the open subsets U of M such that, for all vector bundles E over M and all linear connections ∇ on E, any ∇-parallel section in E defined on U extends to a ∇-parallel section in E defined on M? For simply connected manifolds M (among others) I describe the entirety of all such sets U which are, in addition, the complement of a C1 submanifold, boundary allowed, of M. This delivers a partial positive answer to a problem posed by Antonio J. Di Scala and Gianni Manno (2014). Furthermore, in case M is an open submanifold of Rn, n ≥ 2, I prove that the complement of U in M, not required to be a submanifold now, can have arbitrarily large n-dimensional Lebesgue measure.

  5. Revisiting perturbations in extended quasidilaton massive gravity

    SciTech Connect

    Heisenberg, Lavinia

    2015-04-01

    In this work we study the theory of extended quasidilaton massive gravity together with the presence of matter fields. After discussing the homogeneous and isotropic fully dynamical background equations, which governs the exact expansion history of the universe, we consider small cosmological perturbations around these general FLRW solutions. The stability of tensor, vector and scalar perturbations on top of these general background solutions give rise to slightly different constraints on the parameters of the theory than those obtained in the approximative assumption of the late-time asymptotic form of the expansion history, which does not correspond to our current epoch. This opens up the possibility of stable FLRW solutions to be compared with current data on cosmic expansion with the restricted parameter space based on theoretical ground.

  6. Extended Lagrange interpolation in L1 spaces

    NASA Astrophysics Data System (ADS)

    Occorsio, Donatella; Russo, Maria Grazia

    2016-10-01

    Let w (x )=e-xβxα , w ¯(x )=x w (x ) and denote by {pm(w)}m,{pn(w¯)}n the corresponding sequences of orthonormal polynomials. The zeros of the polynomial Q2 m +1=pm +1(w )pm(w ¯) are simple and are sufficiently far among them. Therefore it is possible to construct an interpolation process essentially based on the zeros of Q2m+1, which is called "Extended Lagrange Interpolation". Here we study the convergence of this interpolation process in suitable weighted L1 spaces. This study completes the results given by the authors in previous papers in weighted Lup((0 ,+∞ )) , for 1≤p≤∞. Moreover an application of the proposed interpolation process in order to construct an e cient product quadrature scheme for weakly singular integrals is given.

  7. Preparing Cassini Uplink Operations for Extended Mission

    NASA Technical Reports Server (NTRS)

    Maxwell, Jennifer L.; McCullar, Michelle L.; Conner, Diane

    2008-01-01

    The Cassini-Huygens Mission to Saturn and Titan, a joint venture between the National Aeronautics and Space Administration, the European Space Agency, and the Italian Space Agency, is conducting a four-year, prime mission exploring the Saturnian system, including its atmosphere, rings, magnetosphere, moons and icy satellites. Launched in 1997, Cassini began its prime mission in 2004. Cassini is now preparing for a new era, a two-year extended mission to revisit many of the highlights and new discoveries made during the prime mission. Because of the light time delay from Earth to Saturn, and the time needed to coordinate the complicated science and engineering activities that take place on the spacecraft, commanding on Cassini is done in approximately 40-day intervals known as sequences. The Cassini Uplink Operations team is responsible for the final development and validation of the pointing profile and instrument and spacecraft commands that are contained in a sequence. During this final analysis prior to uplink to the spacecraft, thorough and exact evaluation is necessary to ensure there are no mistakes during commanding. In order to perform this evaluation, complete and refined processes and procedures are fundamental. The Uplink Operations team is also responsible for anomaly response during sequence execution, a process in which critical decisions often are made in real-time. Recent anomalies on other spacecraft missions have highlighted two major risks in the operations process: (1) personnel turnover and the retirement of critical knowledge and (2) aging, outdated operations procedures. If other missions are a good barometer, the Cassini extended mission will be presented with a high personnel turnover of the Cassini flight team, which could lead to a loss of expertise that has been essential to the success of the prime mission. In order to prepare the Cassini Uplink Operations Team for this possibility and to continue to develop and operate safe science and

  8. IRAS observations of extended zodiacal structures

    NASA Technical Reports Server (NTRS)

    Sykes, Mark V.

    1988-01-01

    In 1983, the Infrared Astronomical Satellite discovered two pairs of dust bands, straddling the ecliptic plane and located in the asteroid belt. New analysis of the IRAS data has resulted in the detection of as many as eight additional bands, spread over more than 40 deg of ecliptic latitude. Dust band morphology is found to vary between different band pairs, having a typical apparent width of a few degrees. This limits the total number of bands which can be distinguished to near the number observed. The Tempel 2 and Encke dust trails are observed to extend over much more of their orbits than had been previously reported, and a new type of dust trail is found which has a relatively large angular width and no imbedded cometary source.

  9. Angle-resolved photoemission extended fine structure

    SciTech Connect

    Barton, J.J.

    1985-03-01

    Measurements of the Angle-Resolved Photoemission Extended Fine Structure (ARPEFS) from the S(1s) core level of a c(2 x 2)S/Ni(001) are analyzed to determine the spacing between the S overlayer and the first and second Ni layers. ARPEFS is a type of photoelectron diffraction measurement in which the photoelectron kinetic energy is swept typically from 100 to 600 eV. By using this wide range of intermediate energies we add high precision and theoretical simplification to the advantages of the photoelectron diffraction technique for determining surface structures. We report developments in the theory of photoelectron scattering in the intermediate energy range, measurement of the experimental photoemission spectra, their reduction to ARPEFS, and the surface structure determination from the ARPEFS by combined Fourier and multiple-scattering analyses. 202 refs., 67 figs., 2 tabs.

  10. Topological Characterization of Extended Quantum Ising Models.

    PubMed

    Zhang, G; Song, Z

    2015-10-23

    We show that a class of exactly solvable quantum Ising models, including the transverse-field Ising model and anisotropic XY model, can be characterized as the loops in a two-dimensional auxiliary space. The transverse-field Ising model corresponds to a circle and the XY model corresponds to an ellipse, while other models yield cardioid, limacon, hypocycloid, and Lissajous curves etc. It is shown that the variation of the ground state energy density, which is a function of the loop, experiences a nonanalytical point when the winding number of the corresponding loop changes. The winding number can serve as a topological quantum number of the quantum phases in the extended quantum Ising model, which sheds some light upon the relation between quantum phase transition and the geometrical order parameter characterizing the phase diagram.

  11. Life extending control: An interdisciplinary engineering thrust

    NASA Technical Reports Server (NTRS)

    Lorenzo, Carl F.; Merrill, Walter C.

    1991-01-01

    The concept of Life Extending Control (LEC) is introduced. Possible extensions to the cyclic damage prediction approach are presented based on the identification of a model from elementary forms. Several candidate elementary forms are presented. These extensions will result in a continuous or differential form of the damage prediction model. Two possible approaches to the LEC based on the existing cyclic damage prediction method, the measured variables LEC and the estimated variables LEC, are defined. Here, damage estimates or measurements would be used directly in the LEC. A simple hydraulic actuator driven position control system example is used to illustrate the main ideas behind LEC. Results from a simple hydraulic actuator example demonstrate that overall system performance (dynamic plus life) can be maximized by accounting for component damage in the control design.

  12. Action principles for extended magnetohydrodynamic models

    NASA Astrophysics Data System (ADS)

    Keramidas Charidakos, I.; Lingam, M.; Morrison, P. J.; White, R. L.; Wurm, A.

    2014-09-01

    The general, non-dissipative, two-fluid model in plasma physics is Hamiltonian, but this property is sometimes lost or obscured in the process of deriving simplified (or reduced) two-fluid or one-fluid models from the two-fluid equations of motion. To ensure that the reduced models are Hamiltonian, we start with the general two-fluid action functional, and make all the approximations, changes of variables, and expansions directly within the action context. The resulting equations are then mapped to the Eulerian fluid variables using a novel nonlocal Lagrange-Euler map. Using this method, we recover Lüst's general two-fluid model, extended magnetohydrodynamic (MHD), Hall MHD, and electron MHD from a unified framework. The variational formulation allows us to use Noether's theorem to derive conserved quantities for each symmetry of the action.

  13. Electrodynamic tether system study: Extended study

    NASA Technical Reports Server (NTRS)

    1988-01-01

    This document is the final report of a study performed by Ball Space Systems Division (BSSD) for the NASA Johnson Space Center under an extension to contract NAS9-17666. The tasks for the extended study were as follows: (1) Define an interface between the Electrodynamic Tether System (ETS) and the Space Station (SS); (2) Identify growth paths for the 100 kW ETS defined in the original study to a 200 kW level of performance; (3) Quantify orbit perturbations caused by cyclic day/night operations of a Plasma Motor/Generator (PMG) on the SS and explore methods of minimizing these effects; (4) Define the analyses, precursor technology, ground tests, and precursor demonstrations leading up to a demonstration mission for an electrodynamic tether system that would be capable of producing maneuvering thrust levels of 25 newtons; and (5) Propose a development schedule for the demonstration mission and preliminary cost estimates.

  14. Extended mission/lunar rover, executive summary

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The design project selected to be undertaken by the 1991/92 Aerospace Design Group was that of conceptually designing an Extended Mission Rover for use on the Lunar Surface. This vehicle would serve the function as a mobile base of sorts, and be able to provide future astronauts with a mobile 'shirt-sleeve' self-sufficient living and working environment. Some of the proposed missions would be planetary surface exploration, construction and maintenance, hardware set-up and in-situ resource experimentation. The need for this type of vehicle has already been declared in the Stafford Group's report on the future of America's Space Program, entitled 'America at the Threshold: America's Space Exploration Initiative'. In the four architectures described within the report, the concept of a pressurized vehicle occurred multiple times. The approximate time frame that this vehicle would be put into use is 2010-2030.

  15. Autopoiesis + extended cognition + nature = can buildings think?

    PubMed Central

    Dollens, Dennis

    2015-01-01

    To incorporate metabolic, bioremedial functions into the performance of buildings and to balance generative architecture's dominant focus on computational programming and digital fabrication, this text first discusses hybridizing Maturana and Varela's biological theory of autopoiesis with Andy Clark's hypothesis of extended cognition. Doing so establishes a procedural protocol to research biological domains from which design could source data/insight from biosemiotics, sensory plants, and biocomputation. I trace computation and botanic simulations back to Alan Turing's little-known 1950s Morphogenetic drawings, reaction-diffusion algorithms, and pioneering artificial intelligence (AI) in order to establish bioarchitecture's generative point of origin. I ask provocatively, Can buildings think? as a question echoing Turing's own, "Can machines think?" PMID:26478784

  16. Relic gravitational waves and extended inflation

    NASA Technical Reports Server (NTRS)

    Turner, Michael S.; Wilczek, Frank

    1990-01-01

    In extended inflation, a new version of inflation where the transition from the false-vacuum phase to a radiation-dominated Universe is accomplished by bubble nucleation and percolation, bubble collisions supply a potent-and potentially detectable-source of gravitational waves. The present energy density in relic gravity waves from bubble collisions is expected to be about 10(exp -5) of closure density-many orders of magnitude greater than that of the gravity waves produced by quantum fluctuations. Their characteristic wavelength depends upon the reheating temperature T(sub RH): lambda is approximately 10(exp 4) cm (10(exp 14) GeV/T(sub RH)). If large numbers of black holes are produced, a not implausible outcome, they will evaporate producing comparable amounts of shorter wavelength waves, lambda is approximately 10(exp -6) cm (T(sub RH)/10(exp 14) GeV).

  17. Extended Performance 8-cm Mercury Ion Thruster

    NASA Technical Reports Server (NTRS)

    Mantenieks, M. A.

    1981-01-01

    A slightly modified 8-cm Hg ion thruster demonstrated significant increase in performance. Thrust was increased by almost a factor of five over that of the baseline thruster. Thruster operation with various three grid ion optics configurations; thruster performance as a function of accelerator grid open area, cathode baffle, and cathode orifice size; and a life test of 614 hours at a beam current of 250 mA (17.5 mN thrust) are discussed. Highest thruster efficiency was obtained with the smallest open area accelerator grid. The benefits in efficiency from the low neutral loss grids were mitigated, however, by the limitation such grids place on attainable ion beam current densities. The thruster components suffered negligible weight losses during a life test, which indicated that operation of the 8-cm thruster at extended levels of thrust and power is possible with no significant loss of lifetime.

  18. Extended performance technology study 30-cm thruster

    NASA Technical Reports Server (NTRS)

    Beattie, J. R.

    1983-01-01

    The extended performance technology study was an investigation of advanced discharge chambers and thruster components that were designed to operate under conditions which result in an increase in the thrust and thrust to power ratio of the state of the art J-series thruster. The high level of performance was achieved by a discharge chamber that employs a ring cusp magnetic confinement arrangement and a three grid ion extraction assembly. It is shown that the ring cusp magnetic field geometry confines the plasma to the volume immediately adjacent to the ion extraction assembly. A high emission current hollow cathode that demonstrated operation at an emission current as high as J sub E = 40 A, and measurements which show the breakdown voltage of individual sections of the J-series propellant flow electrical isolator is about 340 V per section are investigated.

  19. Extending stochastic network calculus to loss analysis.

    PubMed

    Luo, Chao; Yu, Li; Zheng, Jun

    2013-01-01

    Loss is an important parameter of Quality of Service (QoS). Though stochastic network calculus is a very useful tool for performance evaluation of computer networks, existing studies on stochastic service guarantees mainly focused on the delay and backlog. Some efforts have been made to analyse loss by deterministic network calculus, but there are few results to extend stochastic network calculus for loss analysis. In this paper, we introduce a new parameter named loss factor into stochastic network calculus and then derive the loss bound through the existing arrival curve and service curve via this parameter. We then prove that our result is suitable for the networks with multiple input flows. Simulations show the impact of buffer size, arrival traffic, and service on the loss factor.

  20. [Enterobacteria producing extended spectrum beta-lactamases].

    PubMed

    Lucet, J C; Régnier, B

    1998-04-01

    Extended-spectrum beta-lactamases (ESBL) were first observed in 1983. Since then, the number and variety of ESBLs have increased rapidly, particularly in France, and their distribution is now worldwide. The number of ESBLs has now reached more than 30, some of them spreading largely in several countries, such as SHV-4 in France. Intensive care units were first involved. Patients from nursing homes may recirculate ESBLs into acute care units. ESBL clinical epidemiology does not differ from other enterobacteriaceae. Digestive tract is the main reservoir, hands are the route of transmission. Infection develops in about 50% of colonized patients, more than one-half being urinary tract infections. Risk factors for colonization or infection are length of exposure to an epidemic strain and frequency of health-care-worker contact. Strategies for containing spreading of ESBL-producing strains include use of barrier precautions for carriers. Judicious use of antimicrobial agents is also important, by decreasing antibiotic selective pressure.

  1. Nanodosimetric track structure in homogeneous extended beams.

    PubMed

    Conte, V; Moro, D; Colautti, P; Grosswendt, B

    2015-09-01

    Physical aspects of particle track structure are important in determining the induction of clustered damage in relevant subcellular structures like the DNA and higher-order genomic structures. The direct measurement of track-structure properties of ionising radiation is feasible today by counting the number of ionisations produced inside a small gas volume. In particular, the so-called track-nanodosimeter, installed at the TANDEM-ALPI accelerator complex of LNL, measures ionisation cluster-size distributions in a simulated subcellular structure of dimensions 20 nm, corresponding approximately to the diameter of the chromatin fibre. The target volume is irradiated by pencil beams of primary particles passing at specified impact parameter. To directly relate these measured track-structure data to radiobiological measurements performed in broad homogeneous particle beams, these data can be integrated over the impact parameter. This procedure was successfully applied to 240 MeV carbon ions and compared with Monte Carlo simulations for extended fields.

  2. Dynamical Symmetry Breaking of Extended Gauge Symmetries

    NASA Astrophysics Data System (ADS)

    Appelquist, Thomas; Shrock, Robert

    2003-05-01

    We construct asymptotically free gauge theories exhibiting dynamical breaking of the left-right gauge group GLR=SU(3)c×SU(2)L×SU(2)R×U(1)B-L, and its extension to the Pati-Salam gauge group G422=SU(4)PS×SU(2)L×SU(2)R. The models incorporate technicolor for electroweak breaking, and extended technicolor for the breaking of GLR and G422 and the generation of fermion masses. They include a seesaw mechanism for neutrino masses, without a grand unified theory (GUT) scale. These models explain why GLR and G422 break to SU(3)c×SU(2)L×U(1)Y, and why this takes place at a scale (˜103 TeV) large compared to the electroweak scale, but much smaller than a GUT scale.

  3. Extended Ehrenfest theorem with radiative corrections

    NASA Astrophysics Data System (ADS)

    de la Peña, L.; Cetto, A. M.; Valdés-Hernández, A.

    2015-10-01

    A set of basic evolution equations for the mean values of dynamical variables is obtained from the Fokker-Planck equation applied to the general problem of a particle subject to a random force. The specific case of stochastic electrodynamics is then considered, in which the random force is due to the zero-point radiation field. Elsewhere it has been shown that when this system reaches a state of energy balance, it becomes controlled by an equation identical to Schrödinger’s, if the radiationless approximation is made. The Fokker-Planck equation was shown to lead to the Ehrenfest theorem under such an approximation. Here we show that when the radiative terms are not neglected, an extended form of the Ehrenfest equation is obtained, from which follow, among others, the correct formulas for the atomic lifetimes and the (nonrelativistic) Lamb shift.

  4. Extended distribution functions for our Galaxy

    NASA Astrophysics Data System (ADS)

    Sanders, Jason L.; Binney, James

    2015-06-01

    We extend models of our Galaxy based on distribution functions that are analytic functions of the action integrals to extended distribution functions (EDFs), which have an analytic dependence on metallicity as well. We use a simple, but physically motivated, functional forms for the metallicity of the interstellar medium as a function of radius and time and for the star formation rate, and a model for the diffusion of stars through phase space to suggest the required functional form of an EDF. We introduce a simple prescription for radial migration that preserves the overall profile of the disc while allowing individual stars to migrate throughout the disc. Our models explicitly consider the thin and thick discs as two distinct components separated in age. We show how an EDF can be used to incorporate realistic selection functions in models, and to construct mock catalogues of observed samples. We show that the selection function of the Geneva-Copenhagen Survey (GCS) biases in favour of young stars, which have atypically small random velocities. With the selection function taken into account our models produce good fits of the GCS data in chemo-dynamical space and the Gilmore & Reid (1983) density data. From our EDF, we predict the structure of the Sloan Extension for Galactic Understanding and Exploration G-dwarf sample. The kinematics are successfully predicted. The predicted metallicity distribution has too few stars with [Fe/H] ≃ -0.5 dex and too many metal-rich stars. A significant problem may be the lack of any chemical-kinematic correlations in our thick disc. We argue that EDFs will prove essential tools for the analysis of both observational data and sophisticated models of Galaxy formation and evolution.

  5. Beyond six parameters: Extending Λ CDM

    NASA Astrophysics Data System (ADS)

    Di Valentino, Eleonora; Melchiorri, Alessandro; Silk, Joseph

    2015-12-01

    Cosmological constraints are usually derived under the assumption of a six-parameter Λ CDM theoretical framework or simple one-parameter extensions. In this paper we present, for the first time, cosmological constraints in a significantly extended scenario, varying up to 12 cosmological parameters simultaneously, including the sum of neutrino masses, the neutrino effective number, the dark energy equation of state, the gravitational wave background and the running of the spectral index of primordial perturbations. Using the latest Planck 2015 data release (with polarization), we found no significant indication for extensions to the standard Λ CDM scenario, with the notable exception of the angular power spectrum lensing amplitude, Alens , which is larger than the expected value at more than 2 standard deviations, even when combining the Planck data with BAO and supernovae type Ia external data sets. In our extended cosmological framework, we find that a combined Planck+BAO analysis constrains the value of the rms density fluctuation parameter to σ8=0.781-0.063+0.065 at 95 % C.L., helping to relieve the possible tensions with the CFHTlenS cosmic shear survey. We also find a lower value for the reionization optical depth τ =0.058-0.043+0.040 at 95 % C.L. with respect to the one derived under the assumption of Λ CDM . The scalar spectral index nS is now compatible with a Harrison-Zeldovich spectrum to within 2.5 standard deviations. Combining the Planck data set with the Hubble Space Telescope prior on the Hubble constant provides a value for the equation of state w <-1 at more than 2 standard deviations, while the neutrino effective number is fully compatible with the expectations of the standard three neutrino framework.

  6. Reconnection in compressible plasmas: Extended conversion region

    SciTech Connect

    Birn, J.; Hesse, M.; Zenitani, S.

    2011-11-15

    The classical Sweet-Parker approach to steady-state magnetic reconnection is extended into the regime of large resistivity (small magnetic Reynolds or Lundquist number) when the aspect ratio between the outflow and inflow scale, {delta} = d/L, approaches unity. In a previous paper [Paper I, Hesse et al., Phys. Plasmas 18, 042104 (2011)], the vicinity of the dissipation site (''diffusion region'') was investigated. In this paper, the approach is extended to cover larger sites, in which the energy transfer and conversion is not confined to the diffusion region. Consistent with the results of Paper I, we find that increasing aspect ratio {delta} is associated with increasing compression, increasing reconnection rate for low {beta}, but slightly decreasing rate for higher {beta}, decreasing outflow speed, and increasing outflow magnetic field. These trends are stronger for lower {beta}. Deviations from the traditional Sweet-Parker limit {delta}{yields} 0 become significant for R{sub m}<{approx}10, where R{sub m} is the magnetic Reynolds number (Lundquist number) based on the half-thickness of the current layer responsible for the Ohmic dissipation. They are also more significant for small {gamma}, that is, for increasing compressibility. In contrast to the results of Paper I, but consistent with earlier results for {delta}<<1, we find that in this limit the outflow speed is given by the Alfven speed {nu}{sub A} in the inflow region and the energy conversion is given by an even split of Poynting flux into enthalpy flux and bulk kinetic energy flux. However, with increasing {delta} the conversion to enthalpy flux becomes more and more dominant.

  7. The extended Estabrook-Wahlquist method

    NASA Astrophysics Data System (ADS)

    Choudhury, S. Roy; Russo, Matthew

    2016-07-01

    Variable Coefficient Korteweg de Vries (vcKdV), modified Korteweg de Vries (vcMKdV), and nonlinear Schrödinger (NLS) equations have a long history dating from their derivation in various applications. A technique based on extended Lax Pairs has been devised recently to derive time-and-space-dependent-coefficient generalizations of various such Lax-integrable NLPDE hierarchies, which are thus more general than almost all cases considered earlier via methods such as the Painlevé Test, Bell Polynomials, and similarity methods. However, this technique, although operationally effective, has the significant disadvantage that, for any integrable system with spatiotemporally varying coefficients, one must 'guess' a generalization of the structure of the known Lax Pair for the corresponding system with constant coefficients. Motivated by the somewhat arbitrary nature of the above procedure, we embark in this paper on an attempt to systematize the derivation of Lax-integrable systems with variable coefficients. We consider the Estabrook-Wahlquist (EW) prolongation technique, a relatively self-consistent procedure requiring little prior information. However, this immediately requires that the technique be significantly generalized in several ways, including solving matrix partial differential equations instead of algebraic ones as the structure of the Lax Pair is systematically computed, and also in solving the constraint equations to deduce the explicit forms for various 'coefficient' matrices. The new and extended EW technique which results is illustrated by algorithmically deriving generalized Lax-integrable versions of the NLS, generalized fifth-order KdV, MKdV, and derivative nonlinear Schrödinger (DNLS) equations. We also show how this method correctly excludes the existence of a nontrivial Lax pair for a nonintegrable NLPDE such as the variable-coefficient cubic-quintic NLS.

  8. Reconnection in compressible plasmas: Extended conversion region

    NASA Astrophysics Data System (ADS)

    Birn, J.; Hesse, M.; Zenitani, S.

    2011-11-01

    The classical Sweet-Parker approach to steady-state magnetic reconnection is extended into the regime of large resistivity (small magnetic Reynolds or Lundquist number) when the aspect ratio between the outflow and inflow scale, δ = d/L, approaches unity. In a previous paper [Paper I, Hesse et al., Phys. Plasmas 18, 042104 (2011)], the vicinity of the dissipation site ("diffusion region") was investigated. In this paper, the approach is extended to cover larger sites, in which the energy transfer and conversion is not confined to the diffusion region. Consistent with the results of Paper I, we find that increasing aspect ratio δ is associated with increasing compression, increasing reconnection rate for low β, but slightly decreasing rate for higher β, decreasing outflow speed, and increasing outflow magnetic field. These trends are stronger for lower β. Deviations from the traditional Sweet-Parker limit δ → 0 become significant for Rm <~10, where Rm is the magnetic Reynolds number (Lundquist number) based on the half-thickness of the current layer responsible for the Ohmic dissipation. They are also more significant for small γ, that is, for increasing compressibility. In contrast to the results of Paper I, but consistent with earlier results for δ ≪1, we find that in this limit the outflow speed is given by the Alfvén speed νA in the inflow region and the energy conversion is given by an even split of Poynting flux into enthalpy flux and bulk kinetic energy flux. However, with increasing δ the conversion to enthalpy flux becomes more and more dominant.

  9. Reconnection in Compressible Plasmas: Extended Conversion Region

    NASA Technical Reports Server (NTRS)

    Birn, J.; Hesse, M.; Zenitani, S.

    2011-01-01

    The classical Sweet-Parker approach to steady-state magnetic reconnection is extended into the regime of large resistivity (small magnetic Reynolds or Lundquist number) when the aspect ratio between the outflow and inflow scale, delta = d/L, approaches unity. In a previous paper the vicinity of the dissipation site ("diffusion region") was investigated. In this paper, the approach is extended to cover larger sites, in which the energy transfer and conversion is not confined to the diffusion region. Consistent with the results of Paper I, we find that increasing aspect ratio delta is associated with increasing compression, increasing reconnect ion rate for low Beta, but slightly decreasing rate for higher Beta, decreasing outflow speed, and increasing outflow magnetic field. These trends are stronger for lower Beta. Deviations from the traditional Sweet-Parker limit delta approaches 0 become significant for R(sub m) approx < 10, where R(sub m) is the magnetic Reynolds number (Lundquist number) based on the half-thickness of the current layer responsible for the Ohmic dissipation. They are also more significant for small gamma, that is, for increasing compressibility. In contrast to the results of Paper I, but consistent with earlier results for delta much < 1,nu(sub A) we find that in this limit the outflow speed is given by the Alfven speed nu(sub A) in the inflow region and the energy conversion is given by an even split of Poynting flux into enthalpy flux and bulk kinetic energy flux. However, with increasing delta the conversion to enthalpy flux becomes more and more dominant.

  10. X-ray imaging of extended magnetic domain walls in Ni80Fe20 wires

    SciTech Connect

    Basu, S.; Fry, P. W.; Allwood, D. A.; Bryan, M. T.; Gibbs, M. R. J.; Schrefl, T.; Im, M.-Y.; Fischer, P.

    2009-06-20

    We have used magnetic transmission X-ray microscopy to image magnetization configurations in 700 nm wide Ni{sub 80}Fe{sub 20} planar wires attached to 'nucleation' pads Domain walls were observed to inject only across half of the wire width but extend to several micrometers in length. Magnetostatic interactions with adjacent wires caused further unusual domain wall behavior. Micromagnetic modeling suggests the extended walls have Neel-like structure along their length and indicates weaker exchange coupling than is often assumed. These observations explain previous measurements of domain wall injection and demonstrate that magnetic domain walls in larger nanowires cannot always be considered as localized entities.

  11. Extended-gate organic field-effect transistor for the detection of histamine in water

    NASA Astrophysics Data System (ADS)

    Minamiki, Tsukuru; Minami, Tsuyoshi; Yokoyama, Daisuke; Fukuda, Kenjiro; Kumaki, Daisuke; Tokito, Shizuo

    2015-04-01

    As part of our ongoing research program to develop health care sensors based on organic field-effect transistor (OFET) devices, we have attempted to detect histamine using an extended-gate OFET. Histamine is found in spoiled or decayed fish, and causes foodborne illness known as scombroid food poisoning. The new OFET device possesses an extended gate functionalized by carboxyalkanethiol that can interact with histamine. As a result, we have succeeded in detecting histamine in water through a shift in OFET threshold voltage. This result indicates the potential utility of the designed OFET devices in food freshness sensing.

  12. Extended trigonometric Cherednik algebras and nonstationary Schrödinger equations with delta-potentials

    NASA Astrophysics Data System (ADS)

    Hartwig, J. T.; Stokman, J. V.

    2013-02-01

    We realize an extended version of the trigonometric Cherednik algebra as affine Dunkl operators involving Heaviside functions. We use the quadratic Casimir element of the extended trigonometric Cherednik algebra to define an explicit nonstationary Schrödinger equation with delta-potential. We use coordinate Bethe ansatz methods to construct solutions of the nonstationary Schrödinger equation in terms of generalized Bethe wave functions. It is shown that the generalized Bethe wave functions satisfy affine difference Knizhnik-Zamolodchikov equations as functions of the momenta. The relation to the vector valued root system analogs of the quantum Bose gas on the circle with delta-function interactions is indicated.

  13. Use of extended laser plasma for generation of high-order harmonics of picosecond duration

    SciTech Connect

    Ganeev, R A; Boltaev, G S; Reyimbaev, Sh; Sherniyozov, Kh; Usmanov, T

    2015-07-31

    We report the results of experimental investigations on the generation of picosecond radiation harmonics in extended laser plasma produced on the surface of different metal targets. The effect of plasma length, heating pulse duration and delay between the heating and transformable pulses on the efficiency of conversion to higher harmonics is studied. The λ = 1064 nm radiation conversion to a short-wavelength (down to 50 nm, 21st harmonic) range in extended plasma of several metals is demonstrated. (interaction of laser radiation with matter. laser plasma)

  14. Developing a general interaction potential for hydrophobic and hydrophilic interactions.

    PubMed

    Donaldson, Stephen H; Røyne, Anja; Kristiansen, Kai; Rapp, Michael V; Das, Saurabh; Gebbie, Matthew A; Lee, Dong Woog; Stock, Philipp; Valtiner, Markus; Israelachvili, Jacob

    2015-02-24

    We review direct force measurements on a broad class of hydrophobic and hydrophilic surfaces. These measurements have enabled the development of a general interaction potential per unit area, W(D) = -2γ(i)Hy exp(-D/D(H)) in terms of a nondimensional Hydra parameter, Hy, that applies to both hydrophobic and hydrophilic interactions between extended surfaces. This potential allows one to quantitatively account for additional attractions and repulsions not included in the well-known combination of electrostatic double layer and van der Waals theories, the so-called Derjaguin-Landau-Verwey-Overbeek (DLVO) theory. The interaction energy is exponentially decaying with decay length D(H) ≈ 0.3-2 nm for both hydrophobic and hydrophilic interactions, with the exact value of D(H) depending on the precise system and conditions. The pre-exponential factor depends on the interfacial tension, γ(i), of the interacting surfaces and Hy. For Hy > 0, the interaction potential describes interactions between partially hydrophobic surfaces, with the maximum hydrophobic interaction (i.e., two fully hydrophobic surfaces) corresponding to Hy = 1. Hydrophobic interactions between hydrophobic monolayer surfaces measured with the surface forces apparatus (SFA) are shown to be well described by the proposed interaction potential. The potential becomes repulsive for Hy < 0, corresponding to partially hydrophilic (hydrated) interfaces. Hydrated surfaces such as mica, silica, and lipid bilayers are discussed and reviewed in the context of the values of Hy appropriate for each system.

  15. Extending classical molecular theory with polarization.

    PubMed

    Keyes, Tom; Napoleon, Raeanne L

    2011-01-27

    A classical, polarizable, electrostatic theory of short-ranged atom-atom interactions, incorporating the smeared nature of atomic partial charges, is presented. Detailed models are constructed for CO monomer and for CO interacting with an iron atom, as a first step toward heme proteins. A good representation is obtained of the bond-length-dependent dipole of CO monomer from fitting at the equilibrium distance only. Essential features of the binding of CO to myoglobin (Mb) and model heme compounds, including the binding energy, the position of the minimum in the Fe-C potential, the Fe-C frequency, the bending energy, the linear geometry of FeCO, and the increase of the Stark tuning rate and IR intensity, are obtained, suggesting that a substantial part of the Fe-CO interaction consists of a classical, noncovalent, "electrostatic bond ". The binding energy is primarily polarization energy, and the polarization energy of an OH pair in water is shown to be comparable to the experimental hydrogen bond energy.

  16. Interacting faults

    NASA Astrophysics Data System (ADS)

    Peacock, D. C. P.; Nixon, C. W.; Rotevatn, A.; Sanderson, D. J.; Zuluaga, L. F.

    2017-04-01

    The way that faults interact with each other controls fault geometries, displacements and strains. Faults rarely occur individually but as sets or networks, with the arrangement of these faults producing a variety of different fault interactions. Fault interactions are characterised in terms of the following: 1) Geometry - the spatial arrangement of the faults. Interacting faults may or may not be geometrically linked (i.e. physically connected), when fault planes share an intersection line. 2) Kinematics - the displacement distributions of the interacting faults and whether the displacement directions are parallel, perpendicular or oblique to the intersection line. Interacting faults may or may not be kinematically linked, where the displacements, stresses and strains of one fault influences those of the other. 3) Displacement and strain in the interaction zone - whether the faults have the same or opposite displacement directions, and if extension or contraction dominates in the acute bisector between the faults. 4) Chronology - the relative ages of the faults. This characterisation scheme is used to suggest a classification for interacting faults. Different types of interaction are illustrated using metre-scale faults from the Mesozoic rocks of Somerset and examples from the literature.

  17. Should nucleotide sequence analyzing computer algorithms always extend homologies by extending homologies?

    PubMed

    Burnett, L; Basten, A; Hensley, W J

    1986-01-10

    Most computer algorithms used for comparing or aligning nucleotide sequences rely on the premise that the best way to extend a homology between the two sequences is to select a match rather than a mismatch. We have tested this assumption and found that it is not always valid.

  18. Extended Heat Deposition in Hot Jupiters: Application to Ohmic Heating

    NASA Astrophysics Data System (ADS)

    Ginzburg, Sivan; Sari, Re'em

    2016-03-01

    The observed radii of many giant exoplanets in close orbits exceed theoretical predictions. One suggested origin for this discrepancy is heat deposited deep inside the atmospheres of these “hot Jupiters”. Here, we study extended power sources that distribute heat from the photosphere to the deep interior of the planet. Our analytical treatment is a generalization of a previous analysis of localized “point sources”. We model the deposition profile as a power law in the optical depth and find that planetary cooling and contraction halt when the internal luminosity (i.e., cooling rate) of the planet drops below the heat deposited in the planet’s convective region. A slowdown in the evolutionary cooling prior to equilibrium is possible only for sources that do not extend to the planet’s center. We estimate the ohmic dissipation resulting from the interaction between the atmospheric winds and the planet’s magnetic field, and apply our analytical model to ohmically heated planets. Our model can account for the observed radii of most inflated planets, which have equilibrium temperatures of ≈1500-2500 K and are inflated to a radius of ≈ 1.6{R}J. However, some extremely inflated planets remain unexplained by our model. We also argue that ohmically inflated planets have already reached their equilibrium phase, and no longer contract. Following Wu & Lithwick, who argued that ohmic heating could only suspend and not reverse contraction, we calculate the time it takes ohmic heating to re-inflate a cold planet to its equilibrium configuration. We find that while it is possible to re-inflate a cold planet, the re-inflation timescales are longer by a factor of ≈ 30 than the cooling time.

  19. Extending the International Space Station Life and Operability

    NASA Technical Reports Server (NTRS)

    Cecil, Andrew J.; Pitts, R. Lee; Sparks, Ray N.; Wickline, Thomas W.; Zoller, David A.

    2012-01-01

    The International Space Station (ISS) is in an operational configuration with final assembly complete. To fully utilize ISS and extend the operational life, it became necessary to upgrade and extend the onboard systems with the Obsolescence Driven Avionics Redesign (ODAR) project. ODAR enabled a joint project between the Johnson Space Center (JSC) and Marshall Space Flight Center (MSFC) focused on upgrading the onboard payload and Ku-Band systems, expanding the voice and video capabilities, and including more modern protocols allowing unprecedented access for payload investigators to their on-orbit payloads. The MSFC Huntsville Operations Support Center (HOSC) was tasked with developing a high-rate enhanced Functionally Distributed Processor (eFDP) to handle 300Mbps Return Link data, double the legacy rate, and incorporate a Line Outage Recorder (LOR). The eFDP also provides a 25Mbps uplink transmission rate with a Space Link Extension (SLE) interface. HOSC also updated the Payload Data Services System (PDSS) to incorporate the latest Consultative Committee for Space Data Systems (CCSDS) protocols, most notably the use of the Internet Protocol (IP) Encapsulation, in addition to the legacy capabilities. The Central Command Processor was also updated to interact with the new onboard and ground capabilities of Mission Control Center -- Houston (MCC-H) for the uplink functionality. The architecture, implementation, and lessons learned, including integration and incorporation of Commercial Off The Shelf (COTS) hardware and software into the operational mission of the ISS, is described herein. The applicability of this new technology provides new benefits to ISS payload users and ensures better utilization of the ISS by the science community

  20. Comparison of two dilution rates on canine semen quality after cryopreservation in a coconut water extender.

    PubMed

    de Cássia Soares Cardoso, Rita; Silva, Alexandre Rodrigues; da Silva, Lúcia Daniel Machado

    2006-05-01

    The objective of the present study was to evaluate the effect of sperm dilution (one part semen:one part extender or at 200 x 10(6) spermatozoa/mL) using a coconut water extender on the post-thaw sperm quality. Twelve ejaculates were collected from six dogs. Semen was divided into two aliquots, one for dilution one part semen:one part extender (group 1) and another for a concentration of 200 x 10(6) spermatozoa/mL (group 2). Semen was initially extended at 37 degrees C at a proportion of one part semen:half part extender (1:1/2) for group 1 (A-fraction). For group 2, the volume for a concentration of 200 x 10(6) spermatozoa/mL was calculated and a half of this volume was used for the initial dilution (A-fraction, 37 degrees C). Coconut water extender containing 20% egg yolk was used for this initial dilution in both groups. After dilution, the semen was cooled for 40 min in a thermal box (15 degrees C) and for 30 min in a refrigerator. The other half of the extender (B-fraction) containing egg yolk and glycerol (12%) was added to semen in both groups. Subsequently, the final concentration of glycerol in the extender was 6%. Ejaculates were frozen in 0.25 mL straws 5 cm above the surface of liquid nitrogen and stored at -196 degrees C. After 1 week, straws were thawed at 37 degrees C for 1 min and the microscopic criteria were evaluated. The dilution method had no influence on sperm motility, vigor and normal spermatozoa (71.4 compared with 67.7%). There was no effect of dog, ejaculate within male on post-thaw semen quality. Moreover, there was not a male x treatment interaction. Both treatments were efficient in preserving sperm quality.