Kinematics of the thoracic T10-T11 motion segment: locus of instantaneous axes of rotation in flexion and extension.

PubMed

Qiu, Tian-Xia; Teo, Ee-Chon; Lee, Kim-Kheng; Ng, Hong-Wan; Yang, Kai

2004-04-01

The purpose of this study was to determine the locations and loci of instantaneous axes of rotation (IARs) of the T10-T11 motion segment in flexion and extension. An anatomically accurate three-dimensional model of thoracic T10-T11 functional spinal unit (FSU) was developed and validated against published experimental data under flexion, extension, lateral bending, and axial rotation loading configurations. The validated model was exercised under six load configurations that produced motions only in the sagittal plane to characterize the loci of IARs for flexion and extension. The IARs for both flexion and extension under these six load types were directly below the geometric center of the moving vertebra, and all the loci of IARs were tracked superoanteriorly for flexion and inferoposteriorly for extension with rotation. These findings may offer an insight to better understanding of the kinematics of the human thoracic spine and provide clinically relevant information for the evaluation of spinal stability and implant device functionality.

Solar thermal storage applications program

NASA Astrophysics Data System (ADS)

Peila, W. C.

1982-12-01

The efforts of the Storage Applications Program are reviewed. The program concentrated on the investigation of storage media and evaluation of storage methods. Extensive effort was given to experimental and analytical investigations of nitrate salts. Two tasks are the preliminary design of a 1200 MW/sub th/ system and the design, construction, operation, and evaluation of a subsystem research experiment, which utilized the same design. Some preliminary conclusions drawn from the subsystem research experiment are given.

Using a "Makerspace" Approach to Engage Indonesian Primary Students with STEM

ERIC Educational Resources Information Center

Blackley, Susan; Rahmawati, Yuli; Fitriani, Ella; Sheffield, Rachel; Koul, Rekha

2018-01-01

This paper examines the learning experiences of 291 Year 5 and 6 Indonesian primary school students, across four schools in North Jakarta, who participated in an integrated STEM project that used a 3-phase "Makerspace" approach: exposure, engagement and experimentation, and evaluation and extension. The Wiggle Bots project involved these…

Evaluation of effects of fertilizers on narrow brown leaf spot in organic rice, 2010

USDA-ARS?s Scientific Manuscript database

The experiment was established in a field of League soil (3% sand, 32% silt, and 64% clay) under organic management for many years at the Texas A&M University System's Agrilife Research and Extension Center, Beaumont. The experiment was conducted as a two factorial experimental design with five orga...

Evaluation of high temperature structural adhesives for extended service, phase 4

NASA Technical Reports Server (NTRS)

Hendricks, C. L.; Hill, S. G.; Hale, J. N.

1985-01-01

The evaluation of three phenylquinoxaline polymers as high temperature structural adhesives is presented. These included an experimental crisskubjabke oiktner (X-PQ) and two experimental materials (PPQ-2501) and (PPQ-HC). Lap shear, crack extension, and climing drum peel specimens were fabricated from all three polymers, and tested after thermal, combined thermal/humidity, and stressed Skydrol exposure. All three polymers generally performed well as adhesives at initial test temperatures from 219K (-67 F) to 505K (450 F) and after humidity exposure. The 644K (700 F) cured test specimens exhibited superior Skydrol resistance and thermal stability at 505K (450 F) when compared to the 602K (625 F) cured test specimens.

A comparative study of the constitutive models for silicon carbide

NASA Astrophysics Data System (ADS)

Ding, Jow-Lian; Dwivedi, Sunil; Gupta, Yogendra

2001-06-01

Most of the constitutive models for polycrystalline silicon carbide were developed and evaluated using data from either normal plate impact or Hopkinson bar experiments. At ISP, extensive efforts have been made to gain detailed insight into the shocked state of the silicon carbide (SiC) using innovative experimental methods, viz., lateral stress measurements, in-material unloading measurements, and combined compression shear experiments. The data obtained from these experiments provide some unique information for both developing and evaluating material models. In this study, these data for SiC were first used to evaluate some of the existing models to identify their strength and possible deficiencies. Motivated by both the results of this comparative study and the experimental observations, an improved phenomenological model was developed. The model incorporates pressure dependence of strength, rate sensitivity, damage evolution under both tension and compression, pressure confinement effect on damage evolution, stiffness degradation due to damage, and pressure dependence of stiffness. The model developments are able to capture most of the material features observed experimentally, but more work is needed to better match the experimental data quantitatively.

Heat transfer correlations for multilayer insulation systems

NASA Astrophysics Data System (ADS)

Krishnaprakas, C. K.; Badari Narayana, K.; Dutta, Pradip

2000-01-01

Multilayer insulation (MLI) blankets are extensively used in spacecrafts as lightweight thermal protection systems. Heat transfer analysis of MLI is sometimes too complex to use in practical design applications. Hence, for practical engineering design purposes, it is necessary to have simpler procedures to evaluate the heat transfer rate through MLI. In this paper, four different empirical models for heat transfer are evaluated by fitting against experimentally observed heat flux through MLI blankets of various configurations, and the results are discussed.

Information Foraging and Change Detection for Automated Science Exploration

NASA Technical Reports Server (NTRS)

Furlong, P. Michael; Dille, Michael

2016-01-01

This paper presents a new algorithm for autonomous on-line exploration in unknown environments. The objective is to free remote scientists from possibly-infeasible extensive preliminary site investigation prior to sending robotic agents. We simulate a common exploration task for an autonomous robot sampling the environment at various locations and compare performance against simpler control strategies. An extension is proposed and evaluated that further permits operation in the presence of environmental variability in which the robot encounters a change in the distribution underlying sampling targets. Experimental results indicate a strong improvement in performance across varied parameter choices for the scenario.

Efficacy of Prophyt when combined with Captec for control of peach scab in Alabama, 2014

USDA-ARS?s Scientific Manuscript database

Fungicides were evaluated for control of scab in a mid-ripening peach experimental block (‘Ruston Red’) located at the Chilton Area Research and Extension Center located in Clanton, AL. Chemical formulations were applied with an airblast sprayer (100 gal/A spray volume) at the petal fall and shuck s...

ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 9. Extensible thermodynamic constraints for pure compounds and new model developments.

PubMed

Diky, Vladimir; Chirico, Robert D; Muzny, Chris D; Kazakov, Andrei F; Kroenlein, Kenneth; Magee, Joseph W; Abdulagatov, Ilmutdin; Frenkel, Michael

2013-12-23

ThermoData Engine (TDE) is the first full-scale software implementation of the dynamic data evaluation concept, as reported in this journal. The present article describes the background and implementation for new additions in latest release of TDE. Advances are in the areas of program architecture and quality improvement for automatic property evaluations, particularly for pure compounds. It is shown that selection of appropriate program architecture supports improvement of the quality of the on-demand property evaluations through application of a readily extensible collection of constraints. The basis and implementation for other enhancements to TDE are described briefly. Other enhancements include the following: (1) implementation of model-validity enforcement for specific equations that can provide unphysical results if unconstrained, (2) newly refined group-contribution parameters for estimation of enthalpies of formation for pure compounds containing carbon, hydrogen, and oxygen, (3) implementation of an enhanced group-contribution method (NIST-Modified UNIFAC) in TDE for improved estimation of phase-equilibrium properties for binary mixtures, (4) tools for mutual validation of ideal-gas properties derived through statistical calculations and those derived independently through combination of experimental thermodynamic results, (5) improvements in program reliability and function that stem directly from the recent redesign of the TRC-SOURCE Data Archival System for experimental property values, and (6) implementation of the Peng-Robinson equation of state for binary mixtures, which allows for critical evaluation of mixtures involving supercritical components. Planned future developments are summarized.

The proboscis extension reflex to evaluate learning and memory in honeybees ( Apis mellifera): some caveats

NASA Astrophysics Data System (ADS)

Frost, Elisabeth H.; Shutler, Dave; Hillier, Neil Kirk

2012-09-01

The proboscis extension reflex (PER) is widely used in a classical conditioning (Pavlovian) context to evaluate learning and memory of a variety of insect species. The literature is particularly prodigious for honeybees ( Apis mellifera) with more than a thousand publications. Imagination appears to be the only limit to the types of challenges to which researchers subject honeybees, including all the sensory modalities and a broad diversity of environmental treatments. Accordingly, some remarkable insights have been achieved using PER. However, there are several challenges to evaluating the PER literature that warrant a careful and thorough review. We assess here variation in methods that makes interpretation of studies, even those researching the same question, tenuous. We suggest that the numerous variables that might influence experimental outcomes from PER be thoroughly detailed by researchers. Moreover, the influence of individual variables on results needs to carefully evaluated, as well as among two or more variables. Our intent is to encourage investigation of the influence of numerous variables on PER results.

Evaluations of Energy Spectra of Neutrons Emitted Promptly in Neutron-induced Fission of 235 U and 239 Pu

DOE PAGES

Neudecker, Denise; Talou, Patrick; Kawano, Toshihiko; ...

2018-02-01

The energy spectra of neutrons emitted promptly in the neutron-induced fission reactions of 235U and 239Pu were re-evaluated for ENDF/B-VIII.0. The evaluations presented here are based on a careful modeling of all relevant physics processes, an extensive analysis of experimental data and a detailed quantification of pertinent uncertainties. Energy spectra of neutrons emitted in up to fourth chance fission are considered and both compound and pre-equilibrium processes are included. Also, important nuclear model parameters, such as the average total kinetic energy of the fission fragments and the multiple chance fission probabilities, and their uncertainties are estimated based on experimental knowledge,more » model information and evaluated data. In addition to experimental information already available for ENDF/B-VII.1, these new evaluations make use of recently published experimental data either of high precision or spanning a broad incident energy range, information on legacy measurements explaining discrepancies and recently measured data of the average total kinetic energy as a function of incident neutron energy. The resulting evaluated data and covariances agree well with the experimental database used for the evaluation. However, the evaluated spectra are softer than the 235U and 239Pu ENDF/B-VII.1, JENDL-4.0 and JEFF-3.2 evaluations for incident neutron energies E inc ≤ 1.5 MeV and E inc ≤ 5 MeV, respectively. For E inc > 5 MeV, the evaluated spectra show structures due to the improved modeling which are not present in ENDF/B-VII.1 and JEFF-3.2 but can be observed in JENDL-4.0 evaluations. Part of these new evaluations were adopted for ENDF/B-VIII.0, while the ENDF/B-VII.1 239Pu PFNS was retained for E inc ≤ 5 MeV awaiting more conclusive experimental evidence.« less

Evaluations of Energy Spectra of Neutrons Emitted Promptly in Neutron-induced Fission of 235U and 239Pu

NASA Astrophysics Data System (ADS)

Neudecker, D.; Talou, P.; Kawano, T.; Kahler, A. C.; White, M. C.; Taddeucci, T. N.; Haight, R. C.; Kiedrowski, B.; O'Donnell, J. M.; Gomez, J. A.; Kelly, K. J.; Devlin, M.; Rising, M. E.

2018-02-01

The energy spectra of neutrons emitted promptly in the neutron-induced fission reactions of 235U and 239Pu were re-evaluated for ENDF/B-VIII.0. These evaluations are based on a careful modeling of all relevant physics processes, an extensive analysis of experimental data and a detailed quantification of pertinent uncertainties. Energy spectra of neutrons emitted in up to fourth chance fission are considered and both compound and pre-equilibrium processes are included. Also, important nuclear model parameters, such as the average total kinetic energy of the fission fragments and the multiple chance fission probabilities, and their uncertainties are estimated based on experimental knowledge, model information and evaluated data. In addition to experimental information already available for ENDF/B-VII.1, these new evaluations make use of recently published experimental data either of high precision or spanning a broad incident energy range, information on legacy measurements explaining discrepancies and recently measured data of the average total kinetic energy as a function of incident neutron energy. The resulting evaluated data and covariances agree well with the experimental database used for the evaluation. However, the evaluated spectra are softer than the 235U and 239Pu ENDF/B-VII.1, JENDL-4.0 and JEFF-3.2 evaluations for incident neutron energies Einc ≤ 1.5 MeV and Einc ≤ 5 MeV, respectively. For Einc > 5 MeV, the evaluated spectra show structures due to the improved modeling which are not present in ENDF/B-VII.1 and JEFF-3.2 but can be observed in JENDL-4.0 evaluations. Part of these new evaluations were adopted for ENDF/B-VIII.0, while the ENDF/B-VII.1 239Pu PFNS was retained for Einc ≤ 5 MeV awaiting more conclusive experimental evidence.

Evaluations of Energy Spectra of Neutrons Emitted Promptly in Neutron-induced Fission of 235 U and 239 Pu

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neudecker, Denise; Talou, Patrick; Kawano, Toshihiko

The energy spectra of neutrons emitted promptly in the neutron-induced fission reactions of 235U and 239Pu were re-evaluated for ENDF/B-VIII.0. The evaluations presented here are based on a careful modeling of all relevant physics processes, an extensive analysis of experimental data and a detailed quantification of pertinent uncertainties. Energy spectra of neutrons emitted in up to fourth chance fission are considered and both compound and pre-equilibrium processes are included. Also, important nuclear model parameters, such as the average total kinetic energy of the fission fragments and the multiple chance fission probabilities, and their uncertainties are estimated based on experimental knowledge,more » model information and evaluated data. In addition to experimental information already available for ENDF/B-VII.1, these new evaluations make use of recently published experimental data either of high precision or spanning a broad incident energy range, information on legacy measurements explaining discrepancies and recently measured data of the average total kinetic energy as a function of incident neutron energy. The resulting evaluated data and covariances agree well with the experimental database used for the evaluation. However, the evaluated spectra are softer than the 235U and 239Pu ENDF/B-VII.1, JENDL-4.0 and JEFF-3.2 evaluations for incident neutron energies E inc ≤ 1.5 MeV and E inc ≤ 5 MeV, respectively. For E inc > 5 MeV, the evaluated spectra show structures due to the improved modeling which are not present in ENDF/B-VII.1 and JEFF-3.2 but can be observed in JENDL-4.0 evaluations. Part of these new evaluations were adopted for ENDF/B-VIII.0, while the ENDF/B-VII.1 239Pu PFNS was retained for E inc ≤ 5 MeV awaiting more conclusive experimental evidence.« less

Crystal Growth of ZnSe and Related Ternary Compound Semiconductors by Vapor Transport in Low Gravity

NASA Technical Reports Server (NTRS)

Su, Ching-Hua; Ramachandran, N.

2013-01-01

Crystals of ZnSe and related ternary compounds, such as ZnSeS and ZnSeTe, will be grown by physical vapor transport in the Material Science Research Rack (MSRR) on International Space Station (ISS). The objective of the project is to determine the relative contributions of gravity-driven fluid flows to the compositional distribution, incorporation of impurities and defects, and deviation from stoichiometry observed in the crystals grown by vapor transport as results of buoyance-driven convection and growth interface fluctuations caused by irregular fluid-flows on Earth. The investigation consists of extensive ground-based experimental and theoretical research efforts and concurrent flight experimentation. The objectives of the ground-based studies are (1) obtain the experimental data and conduct the analyses required to define the optimum growth parameters for the flight experiments, (2) perfect various characterization techniques to establish the standard procedure for material characterization, (3) quantitatively establish the characteristics of the crystals grown on Earth as a basis for subsequent comparative evaluations of the crystals grown in a low-gravity environment and (4) develop theoretical and analytical methods required for such evaluations. ZnSe and related ternary compounds have been grown by vapor transport technique with real time in-situ non-invasive monitoring techniques. The grown crystals have been characterized extensively by various techniques to correlate the grown crystal properties with the growth conditions.

An aerodynamic analysis of the autogiro rotor with a comparison between calculated and experimental results

NASA Technical Reports Server (NTRS)

Wheatley, John B

1935-01-01

This report presents an extension of the autogiro theory of Glauert and Lock in which the influence of a pitch varying with the blade radius is evaluated and methods of approximating the effect of blade tip losses and the influence of reversed velocities on the retreating blades are developed. A comparison of calculated and experimental results showed that most of the rotor characteristics could be calculated with reasonable accuracy, and that the type of induced flow assumed has a secondary effect upon the net rotor forces, although the flapping motion is influenced appreciably. An approximate evaluation of the effect of parasite drag on the rotor blades established the importance of including this factor in the analysis.

Extensions of Existing Methods for Use with a New Class of Experimental Designs Useful when There Is Treatment Effect Contamination

ERIC Educational Resources Information Center

Rhoads, Christopher

2011-01-01

Researchers planning a randomized field trial to evaluate the effectiveness of an educational intervention often face the following dilemma. They plan to recruit schools to participate in their study. The question is, "Should the researchers randomly assign individuals (either students or teachers, depending on the intervention) within schools to…

Mitigating exotic impacts: restoring native deer mouse populations elevated by an exotic food subsidy

Treesearch

Dean E. Pearson; Robert J. Fletcher

2008-01-01

The threat posed by exotic organisms to native systems has led to extensive research on exotic invaders, yet management of invasives has progressed relatively slowly. This is partly due to poor understanding of how exotic species management influences native organisms. To address this shortfall, we experimentally evaluated the efficacy of an invasives management tool...

Titanium Honeycomb Panel Testing

NASA Technical Reports Server (NTRS)

Richards, W. Lance; Thompson, Randolph C.

1996-01-01

Thermal-mechanical tests were performed on a titanium honeycomb sandwich panel to experimentally validate the hypersonic wing panel concept and compare test data with analysis. Details of the test article, test fixture development, instrumentation, and test results are presented. After extensive testing to 900 deg. F, non-destructive evaluation of the panel has not detected any significant structural degradation caused by the applied thermal-mechanical loads.

Efficacy of agricultural oil and fungicide combinations as a late dormant treatment for control of peach scab in Alabama, 2016

USDA-ARS?s Scientific Manuscript database

Fungicides were evaluated for control of scab in a mid-ripening peach experimental block (‘Ruston Red’) located at the Chilton Area Research and Extension Center in Clanton, AL. Chemical formulations were applied with an airblast sprayer (112.5 gal/A spray volume). Treatment regimens included a non-...

Evaluating the decision accuracy and speed of clinical data visualizations.

PubMed

Pieczkiewicz, David S; Finkelstein, Stanley M

2010-01-01

Clinicians face an increasing volume of biomedical data. Assessing the efficacy of systems that enable accurate and timely clinical decision making merits corresponding attention. This paper discusses the multiple-reader multiple-case (MRMC) experimental design and linear mixed models as means of assessing and comparing decision accuracy and latency (time) for decision tasks in which clinician readers must interpret visual displays of data. These tools can assess and compare decision accuracy and latency (time). These experimental and statistical techniques, used extensively in radiology imaging studies, offer a number of practical and analytic advantages over more traditional quantitative methods such as percent-correct measurements and ANOVAs, and are recommended for their statistical efficiency and generalizability. An example analysis using readily available, free, and commercial statistical software is provided as an appendix. While these techniques are not appropriate for all evaluation questions, they can provide a valuable addition to the evaluative toolkit of medical informatics research.

Advanced Reservoir Characterization and Evaluation of CO2 Gravity Drainage in the Naturally Fractured Spraberry Trend Area, Class III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knight, Bill; Schechter, David S.

The goal of this project was to assess the economic feasibility of CO2 flooding the naturally fractured Spraberry Trend Area in west Texas. This objective was accomplished through research in four areas: (1) extensive characterization of the reservoirs, (2) experimental studies of crude oil/brine/rock (COBR) interactions in the reservoirs, (3) reservoir performance analysis, and (4) experimental investigations on CO2 gravity drainage in Spraberry whole cores. This provides results of the final year of the six-year project for each of the four areas.

Hierarchic Extensions in the Static and Dynamic Analysis of Elastic Beams. Ph.D. Thesis, 1990 Final Report, May 1990

NASA Technical Reports Server (NTRS)

Watson, Robert A.

1991-01-01

Approximate solutions of static and dynamic beam problems by the p-version of the finite element method are investigated. Within a hierarchy of engineering beam idealizations, rigorous formulations of the strain and kinetic energies for straight and circular beam elements are presented. These formulations include rotating coordinate system effects and geometric nonlinearities to allow for the evaluation of vertical axis wind turbines, the motivating problem for this research. Hierarchic finite element spaces, based on extensions of the polynomial orders used to approximate the displacement variables, are constructed. The developed models are implemented into a general purpose computer program for evaluation. Quality control procedures are examined for a diverse set of sample problems. These procedures include estimating discretization errors in energy norm and natural frequencies, performing static and dynamic equilibrium checks, observing convergence for qualities of interest, and comparison with more exacting theories and experimental data. It is demonstrated that p-extensions produce exponential rates of convergence in the approximation of strain energy and natural frequencies for the class of problems investigated.

Development and evaluation of a musculoskeletal model of the elbow joint complex

NASA Technical Reports Server (NTRS)

Gonzalez, Roger V.; Hutchins, E. L.; Barr, Ronald E.; Abraham, Lawrence D.

1993-01-01

This paper describes the development and evaluation of a musculoskeletal model that represents human elbow flexion-extension and forearm pronation-supination. The length, velocity, and moment arm for each of the eight musculotendon actuators were based on skeletal anatomy and position. Musculotendon parameters were determined for each actuator and verified by comparing analytical torque-angle curves with experimental joint torque data. The parameters and skeletal geometry were also utilized in the musculoskeletal model for the analysis of ballistic elbow joint complex movements. The key objective was to develop a computational model, guided by parameterized optimal control, to investigate the relationship among patterns of muscle excitation, individual muscle forces, and movement kinematics. The model was verified using experimental kinematic, torque, and electromyographic data from volunteer subjects performing ballistic elbow joint complex movements.

Family Implementation of Positive Behavior Support for a Child with Autism: Longitudinal, Single-Case, Experimental, and Descriptive Replication and Extension

ERIC Educational Resources Information Center

Lucyshyn, Joseph M.; Albin, Richard W.; Horner, Robert H.; Mann, Jane C.; Mann, James A.; Wadsworth, Gina

2007-01-01

This study examined the efficacy, social validity, and durability of a positive behavior support (PBS) approach with the family of a girl with autism and severe problem behavior. The study was conducted across a 10-year period beginning when the child was 5 years old. A multiple baseline across family routines design evaluated the functional…

Evaluation of a computational model to predict elbow range of motion

PubMed Central

Nishiwaki, Masao; Johnson, James A.; King, Graham J. W.; Athwal, George S.

2014-01-01

Computer models capable of predicting elbow flexion and extension range of motion (ROM) limits would be useful for assisting surgeons in improving the outcomes of surgical treatment of patients with elbow contractures. A simple and robust computer-based model was developed that predicts elbow joint ROM using bone geometries calculated from computed tomography image data. The model assumes a hinge-like flexion-extension axis, and that elbow passive ROM limits can be based on terminal bony impingement. The model was validated against experimental results with a cadaveric specimen, and was able to predict the flexion and extension limits of the intact joint to 0° and 3°, respectively. The model was also able to predict the flexion and extension limits to 1° and 2°, respectively, when simulated osteophytes were inserted into the joint. Future studies based on this approach will be used for the prediction of elbow flexion-extension ROM in patients with primary osteoarthritis to help identify motion-limiting hypertrophic osteophytes, and will eventually permit real-time computer-assisted navigated excisions. PMID:24841799

Evaluation of Test Methods for Triaxially Braided Composites using a Meso-Scale Finite Element Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Chao

The characterization of triaxially braided composite is complicate due to the nonuniformity of deformation within the unit cell as well as the possibility of the freeedge effect related to the large size of the unit cell. Extensive experimental investigation has been conducted to develop more accurate test approaches in characterizing the actual mechanical properties of the material we are studying. In this work, a meso-scale finite element model is utilized to simulate two complex specimens: notched tensile specimen and tube tensile specimen, which are designed to avoid the free-edge effect and free-edge effect induced premature edge damage. The full fieldmore » strain data is predicted numerically and compared with experimental data obtained by Digit Image Correlation. The numerically predicted tensile strength values are compared with experimentally measured results. The discrepancy between numerically predicted and experimentally measured data, the capability of different test approaches are analyzed and discussed. The presented numerical model could serve as assistance to the evaluation of different test methods, and is especially useful in identifying potential local damage events.« less

Recommended Experimental Procedures for Evaluation of Abrupt Wing Stall Characteristics

NASA Technical Reports Server (NTRS)

Capone, F. J.; Hall, R. M.; Owens, D. B.; Lamar, J. E.; McMillin, S. N.

2003-01-01

This paper presents a review of the experimental program under the Abrupt Wing Stall (AWS) Program. Candidate figures of merit from conventional static tunnel tests are summarized and correlated with data obtained in unique free-to-roll tests. Where possible, free-to-roll results are also correlated with flight data. Based on extensive studies of static experimental figures of merit in the Abrupt Wing Stall Program for four different aircraft configurations, no one specific figure of merit consistently flagged a warning of potential lateral activity when actual activity was seen to occur in the free-to-roll experiments. However, these studies pointed out the importance of measuring and recording the root mean square signals of the force balance.

The Project P.A.T.H.S. in Hong Kong: Work Done and Lessons Learned in a Decade.

PubMed

Shek, Daniel T L; Wu, Florence K Y

2016-02-01

The Project Positive Adolescent Training through Holistic Social Programs is a positive youth development program initiated and financially supported by The Hong Kong Jockey Club Charities Trust. Since 2005, the project has gone through several phases, including the initial phase (2005-2012), school-based extension phase (2009-2016), and community-based extension phase (2013-2017). In the initial phase, with the involvement of academics from 5 universities in Hong Kong, the research team developed youth enhancement programs for junior secondary school students (20 hours per grade), trained the program implementers (20 hours per grade), assisted in the implementation in more than 250 schools, and evaluated the program using multiple evaluation strategies, including a 5-year longitudinal experimental study. In the school-based extension phase, the project was implemented for another cycle (2009-2010 and 2011-2012 school years) and a 6-year longitudinal study was conducted to understand the psychosocial development of Chinese adolescents in Hong Kong. In the community-based extension phase, the programs were administered by social workers in the community settings. Generally speaking, different evaluation findings showed that the programs in Project Positive Adolescent Training through Holistic Social Programs promoted positive development and reduced risk behavior in Chinese adolescents in Hong Kong. Positive youth development attributes and family functioning also have positive contributions to adolescent developmental outcomes over time. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Evolving landscape of low-energy nuclear physics publications

DOE PAGES

Pritychenko, B.

2016-10-01

Evolution of low-energy nuclear physics publications over the last 120 years has been analyzed using nuclear physics databases. An extensive study of Nuclear Science References, Experimental Nuclear Reaction Data (EXFOR), and Evaluated Nuclear Structure Data File (ENSDF) contents provides a unique picture of refereed and non-refereed nuclear physics references. Significant fractional contributions of non-refereed reports, private communications and conference proceedings in EXFOR and ENSDF databases in the 1970’s reflect extensive experimental campaigns and an insufficient number of research journals. This trend has been reversed in recent years because the number of measurements is much lower, while number of journals ismore » higher. In addition, nuclear physics results are mainly published in a limited number of journals, such as Physical Review C and Nuclear Physics A. In the present work, historic publication trends and averages have been extracted and analyzed using nuclear data mining techniques. Lastly, the results of this study and implications are discussed and conclusions presented.« less

Evolving landscape of low-energy nuclear physics publications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pritychenko, B.

Evolution of low-energy nuclear physics publications over the last 120 years has been analyzed using nuclear physics databases. An extensive study of Nuclear Science References, Experimental Nuclear Reaction Data (EXFOR), and Evaluated Nuclear Structure Data File (ENSDF) contents provides a unique picture of refereed and non-refereed nuclear physics references. Significant fractional contributions of non-refereed reports, private communications and conference proceedings in EXFOR and ENSDF databases in the 1970’s reflect extensive experimental campaigns and an insufficient number of research journals. This trend has been reversed in recent years because the number of measurements is much lower, while number of journals ismore » higher. In addition, nuclear physics results are mainly published in a limited number of journals, such as Physical Review C and Nuclear Physics A. In the present work, historic publication trends and averages have been extracted and analyzed using nuclear data mining techniques. Lastly, the results of this study and implications are discussed and conclusions presented.« less

Examining and contrasting the cognitive activities engaged in undergraduate research experiences and lab courses

NASA Astrophysics Data System (ADS)

Holmes, N. G.; Wieman, Carl E.

2016-12-01

While the positive outcomes of undergraduate research experiences (UREs) have been extensively categorized, the mechanisms for those outcomes are less understood. Through lightly structured focus group interviews, we have extracted the cognitive tasks that students identify as engaging in during their UREs. We also use their many comparative statements about their coursework, especially lab courses, to evaluate their experimental physics-related cognitive tasks in those environments. We find there are a number of cognitive tasks consistently encountered in physics UREs that are present in most experimental research. These are seldom encountered in lab or lecture courses, with some notable exceptions. Having time to reflect and fix or revise, and having a sense of autonomy, were both repeatedly cited as key enablers of the benefits of UREs. We also identify tasks encountered in actual experimental research that are not encountered in UREs. We use these findings to identify opportunities for better integration of the cognitive tasks in UREs and lab courses, as well as discussing the barriers that exist. This work responds to extensive calls for science education to better develop students' scientific skills and practices, as well as calls to expose more students to scientific research.

An experimental test of plant canopy reflectance models on cotton

NASA Technical Reports Server (NTRS)

Lemaster, E. W.

1974-01-01

Extensive data on the plant parameters necessary to evaluate any model are presented for a cotton crop. The variation of the bidirectional reflectance function with observer altitude, observer azimuth, and sun altitude angle is presented for a high density cotton crop having leaf index of 19. A comparison with the quantitative behavior obtained from the Suits model is accomplished in the wavelength region from 400 nm to 1050 nm.

A Weibull characterization for tensile fracture of multicomponent brittle fibers

NASA Technical Reports Server (NTRS)

Barrows, R. G.

1977-01-01

A statistical characterization for multicomponent brittle fibers in presented. The method, which is an extension of usual Weibull distribution procedures, statistically considers the components making up a fiber (e.g., substrate, sheath, and surface) as separate entities and taken together as in a fiber. Tensile data for silicon carbide fiber and for an experimental carbon-boron alloy fiber are evaluated in terms of the proposed multicomponent Weibull characterization.

Evaluated cross-section libraries and kerma factors for neutrons up to 100 MeV on {sup 12}C

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chadwick, M.B.; Blann, M.; Cox, L.

1995-04-11

A program is being carried out at Lawrence Livermore National Laboratory to develop high-energy evaluated nuclear data libraries for use in Monte Carlo simulations of cancer radiation therapy. In this report we describe evaluated cross sections and kerma factors for neutrons with incident energies up to 100 MeV on {sup 12}C. The aim of this effort is to incorporate advanced nuclear physics modeling methods, with new experimental measurements, to generate cross section libraries needed for an accurate simulation of dose deposition in fast neutron therapy. The evaluated libraries are based mainly on nuclear model calculations, benchmarked to experimental measurements wheremore » they exist. We use the GNASH code system, which includes Hauser-Feshbach, preequilibrium, and direct reaction mechanisms. The libraries tabulate elastic and nonelastic cross sections, angle-energy correlated production spectra for light ejectiles with A{le}and kinetic energies given to light ejectiles and heavy recoil fragments. The major steps involved in this effort are: (1) development and validation of nuclear models for incident energies up to 100 MeV; (2) collation of experimental measurements, including new results from Louvain-la-Nueve and Los Alamos; (3) extension of the Livermore ENDL formats for representing high-energy data; (4) calculation and evaluation of nuclear data; and (5) validation of the libraries. We describe the evaluations in detail, with particular emphasis on our new high-energy modeling developments. Our evaluations agree well with experimental measurements of integrated and differential cross sections. We compare our results with the recent ENDF/B-VI evaluation which extends up to 32 MeV.« less

Simulator certification methods and the vertical motion simulator

NASA Technical Reports Server (NTRS)

Showalter, T. W.

1981-01-01

The vertical motion simulator (VMS) is designed to simulate a variety of experimental helicopter and STOL/VTOL aircraft as well as other kinds of aircraft with special pitch and Z axis characteristics. The VMS includes a large motion base with extensive vertical and lateral travel capabilities, a computer generated image visual system, and a high speed CDC 7600 computer system, which performs aero model calculations. Guidelines on how to measure and evaluate VMS performance were developed. A survey of simulation users was conducted to ascertain they evaluated and certified simulators for use. The results are presented.

Numerical Simulation with Experimental Validation of the Draping Behavior of Woven Fabrics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodgers, William; Pasupuleti, Praveen; Zhao, Selina

Woven fabric composites are extensively used in molding complex geometrical shapes due to their high conformability compared to other fabrics. Preforming is an important step in the overall process. In this step, the two-dimensional fabric is draped to become the three-dimensional shape of the part prior to resin injection. During preforming, the orientation of the tows may change significantly compared to the initial orientations. Accurate prediction of the tow orientations after molding is important for evaluating the structural performance of the final part. This paper investigates the fiber angle changes for carbon fiber woven fabrics during draping over a truncatedmore » pyramid tool designed and fabricated at the General Motors Research Labs. This aspect of study is a subset of the broad study conducted under the purview of a Department of Energy project funded to GM in developing state of the art computational tools for integrated manufacturing and structural performance prediction of carbon fiber composites. Fabric bending, picture frame testing, and bias-extension evaluations were carried out to determine the material parameters for these fabrics. The PAM-FORM computer program was used to model the draping behavior of these fabrics. Following deformation, fiber angle changes at different locations on the truncated pyramid were measured experimentally. The predicted angles matched the experimental results well as measured along the centerline and at several different locations on the deformed fabric. Details of the test methods used as well as the numerical results with various simulation parameters will be provided.« less

Evaluation of Upland Disposal of Oakland Harbor, California, Sediment; Volume I: Turning Basin Sediments

DTIC Science & Technology

1992-10-01

infiltration studies ( Westerdahl and Skogerboe 1982). Extensive field 53 verification studies have been conducted with the WES Rainfall Simulator...Lysimeter System on a wide range of Corps project sites ( Westerdahl and Skogerboe 1982, Lee and Skogerboe 1984, Skogerboe et al. 1987). The WES Rain- fall...Vicksburg, MS. Winer, B. J. 1971. Statistical Principles in Experimental Design, McGraw- Hill Book Company, New York. Westerdahl , H. E., and Skogerboe, J

Modeling of propulsive jet plumes--extension of modeling capabilities by utilizing wall curvature effects

NASA Astrophysics Data System (ADS)

Doerr, S. E.

1984-06-01

Modeling of aerodynamic interference effects of propulsive jet plumes, by using inert gases as substitute propellants, introduces design limits. To extend the range of modeling capabilities, nozzle wall curvature effects may be utilized. Numerical calculations, using the Method of Characteristics, were made and experimental data were taken to evaluate the merits of the theoretical predictions. A bibliography, listing articles that led to the present report, is included.

Development of a Novel Alginate-Based Pleural Sealant

DTIC Science & Technology

2017-09-01

and will be the subject of ongoing studies . Figure 20: Experimental set-up for endobronchial administration of sealants in the ex vivo pig lung...toxicity. In the studies to date, we have done extensive materials characterization not just of modified alginates but now a number of other biologic...pig) ex vivo lung models and have performed initial in vivo evaluations of several compounds in a non-survival surgery rat lung injury model. The

Evaluation of high temperature structural adhesives for extended service, phase 5

NASA Technical Reports Server (NTRS)

Hendricks, C. L.; Hill, S. G.; Hale, J. N.; Dumars, W. G.

1987-01-01

The evaluation of 3 experimental polymers from NASA-Langley and a commercially produced polymer from Mitsui Toatsu Chemicals as high temperature structural adhesives is presented. A polyphenylquinoxaline (PPQ), polyimide (STPI/LaRC-2), and a polyarylene ether (PAE-SO2) were evaluated as metal-to-metal adhesives. Lap shear, crack extension, and climbing drum peel specimens were fabricated from all three polymers and tested after thermal, combined thermal/humidity, and stressed hydraulic fluid (Skydrol) exposure. The fourth polymer, LARC-TPI was evaluated as an adhesive for titanium honeycomb sandwich structure. All three experimental polymers performed well as metal-to-metal adhesives from 219 K (-65 F) to 505 K (450 F), including humidity exposure. Structural adhesive strength was also maintained at 505 K for a minimum of 3000 hours. LaRC-TPI was evaluated as a high temperature (505 K) adhesive for titanium honeycomb sandwich structure. The LaRC-TPI bonding process development concentrated on improving the honeycomb core-to-skin bond. The most promising approach of those evaluated combined a LaRC-TPI polymer solution with a semi-crystalline LaRC-TPI powder for adhesive film fabrication and fillet formation.

Data base for the prediction of inlet external drag

NASA Technical Reports Server (NTRS)

Mcmillan, O. J.; Perkins, E. W.; Perkins, S. C., Jr.

1980-01-01

Results are presented from a study to define and evaluate the data base for predicting an airframe/propulsion system interference effect shown to be of considerable importance, inlet external drag. The study is focused on supersonic tactical aircraft with highly integrated jet propulsion systems, although some information is included for supersonic strategic aircraft and for transport aircraft designed for high subsonic or low supersonic cruise. The data base for inlet external drag is considered to consist of the theoretical and empirical prediction methods as well as the experimental data identified in an extensive literature search. The state of the art in the subsonic and transonic speed regimes is evaluated. The experimental data base is organized and presented in a series of tables in which the test article, the quantities measured and the ranges of test conditions covered are described for each set of data; in this way, the breadth of coverage and gaps in the existing experimental data are evident. Prediction methods are categorized by method of solution, type of inlet and speed range to which they apply, major features are given, and their accuracy is assessed by means of comparison to experimental data.

Evaluation of the three-dimensional parabolic flow computer program SHIP

NASA Technical Reports Server (NTRS)

Pan, Y. S.

1978-01-01

The three-dimensional parabolic flow program SHIP designed for predicting supersonic combustor flow fields is evaluated to determine its capabilities. The mathematical foundation and numerical procedure are reviewed; simplifications are pointed out and commented upon. The program is then evaluated numerically by applying it to several subsonic and supersonic, turbulent, reacting and nonreacting flow problems. Computational results are compared with available experimental or other analytical data. Good agreements are obtained when the simplifications on which the program is based are justified. Limitations of the program and the needs for improvement and extension are pointed out. The present three dimensional parabolic flow program appears to be potentially useful for the development of supersonic combustors.

High fidelity computational characterization of the mechanical response of thermally aged polycarbonate

NASA Astrophysics Data System (ADS)

Zhang, Zesheng; Zhang, Lili; Jasa, John; Li, Wenlong; Gazonas, George; Negahban, Mehrdad

2017-07-01

A representative all-atom molecular dynamics (MD) system of polycarbonate (PC) is built and conditioned to capture and predict the behaviours of PC in response to a broad range of thermo-mechanical loadings for various thermal aging. The PC system is constructed to have a distribution of molecular weights comparable to a widely used commercial PC (LEXAN 9034), and thermally conditioned to produce models for aged and unaged PC. The MD responses of these models are evaluated through comparisons to existing experimental results carried out at much lower loading rates, but done over a broad range of temperatures and loading modes. These experiments include monotonic extension/compression/shear, unilaterally and bilaterally confined compression, and load-reversal during shear. It is shown that the MD simulations show both qualitative and quantitative similarity with the experimental response. The quantitative similarity is evaluated by comparing the dilatational response under bilaterally confined compression, the shear flow viscosity and the equivalent yield stress. The consistency of the in silico response to real laboratory experiments strongly suggests that the current PC models are physically and mechanically relevant and potentially can be used to investigate thermo-mechanical response to loading conditions that would not easily be possible. These MD models may provide valuable insight into the molecular sources of certain observations, and could possibly offer new perspectives on how to develop constitutive models that are based on better understanding the response of PC under complex loadings. To this latter end, the models are used to predict the response of PC to complex loading modes that would normally be difficult to do or that include characteristics that would be difficult to measure. These include the responses of unaged and aged PC to unilaterally confined extension/compression, cyclic uniaxial/shear loadings, and saw-tooth extension/compression/shear.

Non-Gaussian Distribution of DNA Barcode Extension In Nanochannels Using High-throughput Imaging

NASA Astrophysics Data System (ADS)

Sheats, Julian; Reinhart, Wesley; Reifenberger, Jeff; Gupta, Damini; Muralidhar, Abhiram; Cao, Han; Dorfman, Kevin

2015-03-01

We present experimental data for the extension of internal segments of highly confined DNA using a high-­throughput experimental setup. Barcode­-labeled E. coli genomic DNA molecules were imaged at a high areal density in square nanochannels with sizes ranging from 40 nm to 51 nm in width. Over 25,000 molecules were used to obtain more than 1,000,000 measurements for genomic distances between 2,500 bp and 100,000 bp. The distribution of extensions has positive excess kurtosis and is skew­ left due to weak backfolding in the channel. As a result, the two Odijk theories for the chain extension and variance bracket the experimental data. We compared to predictions of a harmonic approximation for the confinement free energy and show that it produces a substantial error in the variance. These results suggest an inherent error associated with any statistical analysis of barcoded DNA that relies on harmonic models for chain extension. Present address: Department of Chemical and Biological Engineering, Princeton University.

An online database of nuclear electromagnetic moments

NASA Astrophysics Data System (ADS)

Mertzimekis, T. J.; Stamou, K.; Psaltis, A.

2016-01-01

Measurements of nuclear magnetic dipole and electric quadrupole moments are considered quite important for the understanding of nuclear structure both near and far from the valley of stability. The recent advent of radioactive beams has resulted in a plethora of new, continuously flowing, experimental data on nuclear structure - including nuclear moments - which hinders the information management. A new, dedicated, public and user friendly online database (http://magneticmoments.info) has been created comprising experimental data of nuclear electromagnetic moments. The present database supersedes existing printed compilations, including also non-evaluated series of data and relevant meta-data, while putting strong emphasis on bimonthly updates. The scope, features and extensions of the database are reported.

Evaluation of aerodynamic forces acting on oscillating cantilever beams based on the study of the damped flexural vibration of aluminium test samples

NASA Astrophysics Data System (ADS)

Egorov, A. G.; Kamalutdinov, A. M.; Nuriev, A. N.

2018-05-01

The paper is devoted to study of the aerodynamic forces acting on flat cantilever beams performing flexural vibrations in a viscous fluid. Original method for the force evaluation is presented based on analysis of experimental measurements of a logarithmic decrement of vibrations and relative variation in frequency of duralumin test specimens. The theoretical core of the method is based on the classical theory of bending beam oscillations and quasi-two dimensional model of interaction between a beam and a gas. Using the proposed method, extensive series of experiments for a wide range of oscillations parameters were carried out. The processing of the experimental data allowed to establish the global influence of the aerodynamic effects on beam oscillations and the local force characteristics of each cross-section of the beam in the form of universal functions of dimensionless amplitude and dimensionless frequency of oscillation. The obtained estimates of the drag and added mass forces showed a good correspondence with the available numerical and experimental data practically in the entire range of the investigated parameters.

Biomass power for rural development. Technical progress report, January 1--March 31, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

Brief progress reports are presented on the following tasks: design packages for retrofits at the Dunkirk Station; fuel supply and site development plans; major equipment guarantees and project risk sharing; power production commitment; power plant site plan, construction and environmental permits; and experimental strategies for system evaluation. The paper then discusses in more detail the following: feedstock development efforts; clone-site testing and genetic studies; and efforts at outreach, extension and technology transfer.

Mesoscale Particle-Based Model of Electrophoresis

DOE PAGES

Giera, Brian; Zepeda-Ruiz, Luis A.; Pascall, Andrew J.; ...

2015-07-31

Here, we develop and evaluate a semi-empirical particle-based model of electrophoresis using extensive mesoscale simulations. We parameterize the model using only measurable quantities from a broad set of colloidal suspensions with properties that span the experimentally relevant regime. With sufficient sampling, simulated diffusivities and electrophoretic velocities match predictions of the ubiquitous Stokes-Einstein and Henry equations, respectively. This agreement holds for non-polar and aqueous solvents or ionic liquid colloidal suspensions under a wide range of applied electric fields.

Comparative Study of Nonlinear Time Warping Techniques in Isolated Word Speech Recognition Systems

DTIC Science & Technology

1981-06-17

all modules are loaded under a flexible research oriented supervisor, " Cicada ". Cicada allows for the integration of experimental ideas, extensions...evaluate alternate recognition methods. More detailed information about Cicada can be found in7 . In the following we limit our discussion to the design of...43.70 37.78 32.47 44.44 44.32 38 8. Figures Cicada - a flexible research oriented supervisor ReferenceSTernpl ates Front End Matching Digital Signal

Mesoscale Particle-Based Model of Electrophoresis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giera, Brian; Zepeda-Ruiz, Luis A.; Pascall, Andrew J.

Here, we develop and evaluate a semi-empirical particle-based model of electrophoresis using extensive mesoscale simulations. We parameterize the model using only measurable quantities from a broad set of colloidal suspensions with properties that span the experimentally relevant regime. With sufficient sampling, simulated diffusivities and electrophoretic velocities match predictions of the ubiquitous Stokes-Einstein and Henry equations, respectively. This agreement holds for non-polar and aqueous solvents or ionic liquid colloidal suspensions under a wide range of applied electric fields.

The Paucity Problem: Where Have All the Space Reactor Experiments Gone?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bess, John D.; Marshall, Margaret A.

2016-10-01

The Handbooks of the International Criticality Safety Benchmark Evaluation Project (ICSBEP) and the International Reactor Physics Experiment Evaluation Project (IRPhEP) together contain a plethora of documented and evaluated experiments essential in the validation of nuclear data, neutronics codes, and modeling of various nuclear systems. Unfortunately, only a minute selection of handbook data (twelve evaluations) are of actual experimental facilities and mockups designed specifically for space nuclear research. There is a paucity problem, such that the multitude of space nuclear experimental activities performed in the past several decades have yet to be recovered and made available in such detail that themore » international community could benefit from these valuable historical research efforts. Those experiments represent extensive investments in infrastructure, expertise, and cost, as well as constitute significantly valuable resources of data supporting past, present, and future research activities. The ICSBEP and IRPhEP were established to identify and verify comprehensive sets of benchmark data; evaluate the data, including quantification of biases and uncertainties; compile the data and calculations in a standardized format; and formally document the effort into a single source of verified benchmark data. See full abstract in attached document.« less

Investigation of composite materials property requirements for sonic fatigue research

NASA Technical Reports Server (NTRS)

Patrick, H. V. L.

1985-01-01

Experimental techniques for determining the extensional and bending stiffness characteristics for symmetric laminates are presented. Vibrational test techniques for determining the dynamic modulus and material damping are also discussed. Partial extensional stiffness results intially indicate that the laminate theory used for predicting stiffness is accurate. It is clearly shown that the laminate theory can only be as accurate as the physical characteristics describing the lamina, which may vary significantly. It is recommended that all of the stiffness characteristics in both extension and bending be experimentally determined to fully verify the laminate theory. Dynamic modulus should be experimentally evaluated to determine if static data adequately predicts dynamic behavior. Material damping should also be ascertained because laminate damping is an order of magnitude greater than found in common metals and can significantly effect the displacement response of composite panels.

Risk assessment by percolation leaching tests of extensive green roofs with fine fraction of mixed recycled aggregates from construction and demolition waste.

PubMed

López-Uceda, Antonio; Galvín, Adela P; Ayuso, Jesús; Jiménez, José Ramón; Vanwalleghem, Tom; Peña, Adolfo

2018-03-19

Extensive green roofs are urban construction systems that provide thermal regulation and sound proofing for the buildings involved, in addition to providing an urban heat island mitigation or water retention. On the other hand, policies towards reduction of energy consumption, a circular economy and sustainability are core in the European Union. Motivated by this, an experimental study was carried out to evaluate the environmental risk assessment according to release levels of polluting elements on leachates of different green roof substrate mixtures based on recycled aggregates from construction and demolition waste through (i) the performance in laboratory of two procedures: compliance and percolation tests and (ii) an upscaled experimental leaching test for long-term on-site prediction. Four plots were built on a building roof and covered with autochthonous Mediterranean plants in Córdoba, South of Spain. As growing substrate, four mixtures were used of a commercial growing substrate with different proportions of a fine mixed recycled aggregate ranging from 0 to 75% by volume. The results show that these mixtures were classified as non-hazardous materials according to legal limits of the Landfill Directive 2003/33/CE. The release levels registered in extensive green roofs were lower compared to the laboratory test data. This shows how laboratory conditions can overestimate the potential pollutant effect of these materials compared to actual conditions.

Automatic labeling of MR brain images through extensible learning and atlas forests.

PubMed

Xu, Lijun; Liu, Hong; Song, Enmin; Yan, Meng; Jin, Renchao; Hung, Chih-Cheng

2017-12-01

Multiatlas-based method is extensively used in MR brain images segmentation because of its simplicity and robustness. This method provides excellent accuracy although it is time consuming and limited in terms of obtaining information about new atlases. In this study, an automatic labeling of MR brain images through extensible learning and atlas forest is presented to address these limitations. We propose an extensible learning model which allows the multiatlas-based framework capable of managing the datasets with numerous atlases or dynamic atlas datasets and simultaneously ensure the accuracy of automatic labeling. Two new strategies are used to reduce the time and space complexity and improve the efficiency of the automatic labeling of brain MR images. First, atlases are encoded to atlas forests through random forest technology to reduce the time consumed for cross-registration between atlases and target image, and a scatter spatial vector is designed to eliminate errors caused by inaccurate registration. Second, an atlas selection method based on the extensible learning model is used to select atlases for target image without traversing the entire dataset and then obtain the accurate labeling. The labeling results of the proposed method were evaluated in three public datasets, namely, IBSR, LONI LPBA40, and ADNI. With the proposed method, the dice coefficient metric values on the three datasets were 84.17 ± 4.61%, 83.25 ± 4.29%, and 81.88 ± 4.53% which were 5% higher than those of the conventional method, respectively. The efficiency of the extensible learning model was evaluated by state-of-the-art methods for labeling of MR brain images. Experimental results showed that the proposed method could achieve accurate labeling for MR brain images without traversing the entire datasets. In the proposed multiatlas-based method, extensible learning and atlas forests were applied to control the automatic labeling of brain anatomies on large atlas datasets or dynamic atlas datasets and obtain accurate results. © 2017 American Association of Physicists in Medicine.

A survey of keystroke dynamics biometrics.

PubMed

Teh, Pin Shen; Teoh, Andrew Beng Jin; Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions.

Flight Experiments of Physical Vapor Transport of ZnSe: Growth of Crystals in Various Convective Conditions

NASA Technical Reports Server (NTRS)

Su, Ching-Hua

2015-01-01

A low gravity material experiment will be performed in the Material Science Research Rack (MSRR) on International Space Station (ISS). The flight experiment will conduct crystal growths of ZnSe and related ternary compounds, such as ZnSeS and ZnSeTe, by physical vapor transport (PVT). The main objective of the project is to determine the relative contributions of gravity-driven fluid flows to the compositional distribution, incorporation of impurities and defects, and deviation from stoichiometry observed in the grown crystals as results of buoyancy-driven convection and growth interface fluctuations caused by irregular fluid-flows on Earth. The investigation consists of extensive ground-based experimental and theoretical research efforts and concurrent flight experimentation. The objectives of the ground-based studies are (1) obtain the experimental data and conduct the analyses required to define the optimum growth parameters for the flight experiments, (2) perfect various characterization techniques to establish the standard procedure for material characterization, (3) quantitatively establish the characteristics of the crystals grown on Earth as a basis for subsequent comparative evaluations of the crystals grown in a low-gravity environment and (4) develop theoretical and analytical methods required for such evaluations. ZnSe and related ternary compounds have been grown by vapor transport technique with real time in-situ non-invasive monitoring techniques. The grown crystals have been characterized extensively by various techniques to correlate the grown crystal properties with the growth conditions. This talk will focus on the ground-based studies on the PVT crystal growth of ZnSe and related ternary compounds, especially the effects of different growth orientations related to gravity direction on the grown crystals.

Crystal Growth of Ternary Compound Semiconductors in Low Gravity Environment

NASA Technical Reports Server (NTRS)

Su, Ching-Hua

2014-01-01

A low gravity material experiment will be performed in the Material Science Research Rack (MSRR) on International Space Station (ISS). There are two sections of the flight experiment: (I) crystal growth of ZnSe and related ternary compounds, such as ZnSeS and ZnSeTe, by physical vapor transport (PVT) and (II) melt growth of CdZnTe by directional solidification. The main objective of the project is to determine the relative contributions of gravity-driven fluid flows to the compositional distribution, incorporation of impurities and defects, and deviation from stoichiometry observed in the grown crystals as results of buoyancy-driven convection and growth interface fluctuations caused by irregular fluid-flows on Earth. The investigation consists of extensive ground-based experimental and theoretical research efforts and concurrent flight experimentation. This talk will focus on the ground-based studies on the PVT crystal growth of ZnSe and related ternary compounds. The objectives of the ground-based studies are (1) obtain the experimental data and conduct the analyses required to define the optimum growth parameters for the flight experiments, (2) perfect various characterization techniques to establish the standard procedure for material characterization, (3) quantitatively establish the characteristics of the crystals grown on Earth as a basis for subsequent comparative evaluations of the crystals grown in a low-gravity environment and (4) develop theoretical and analytical methods required for such evaluations. ZnSe and related ternary compounds have been grown by vapor transport technique with real time in-situ non-invasive monitoring techniques. The grown crystals have been characterized extensively by various techniques to correlate the grown crystal properties with the growth conditions.

Nuclear Data Sheets for A=40

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Jun

The experimental nuclear structure data and decay data are evaluated for the known nuclides of mass 40 (Mg, Al, Si, P, S, Cl, Ar, K, Ca, Sc, Ti). Detailed evaluated nuclear structure information is presented with the best values recommended for level energies, half-lives, γ-ray energies and intensities, decay properties (energies, intensities and placement of radiations), and other spectroscopic data. The {sup 40}Ca and {sup 40}K nuclides remain as the most extensively studied from many different reactions and decays; no excited states are known in {sup 40}Mg, {sup 40}Al, {sup 40}P and {sup 40}Ti. This work supersedes the earlier fullmore » evaluation of A=40 by J. Cameron and B. Singh (2004Ca38).« less

Recent advances in phase shifted time averaging and stroboscopic interferometry

NASA Astrophysics Data System (ADS)

Styk, Adam; Józwik, Michał

2016-08-01

Classical Time Averaging and Stroboscopic Interferometry are widely used for MEMS/MOEMS dynamic behavior investigations. Unfortunately both methods require an extensive measurement and data processing strategies in order to evaluate the information on maximum amplitude at a given load of vibrating object. In this paper the modified strategies of data processing in both techniques are introduced. These modifications allow for fast and reliable calculation of searched value, without additional complication of measurement systems. Through the paper the both approaches are discussed and experimentally verified.

Performance characterization of polarimetric active radar calibrators and a new single antenna design

NASA Astrophysics Data System (ADS)

Sarabandi, Kamal; Oh, Yisok; Ulaby, Fawwaz T.

1992-10-01

Three aspects of a polarimetric active radar calibrator (PARC) are treated: (1) experimental measurements of the magnitudes and phases of the scattering-matrix elements of a pair of PARCs operating at 1.25 and 5.3 GHz; (2) the design, construction, and performance evaluation of a PARC; and (3) the extension of the single-target-calibration technique (STCT) to a PARC. STCT has heretofore been limited to the use of reciprocal passive calibration devices, such as spheres and trihedral corner reflectors.

Performance characterization of polarimetric active radar calibrators and a new single antenna design

NASA Technical Reports Server (NTRS)

Sarabandi, Kamal; Oh, Yisok; Ulaby, Fawwaz T.

1992-01-01

Three aspects of a polarimetric active radar calibrator (PARC) are treated: (1) experimental measurements of the magnitudes and phases of the scattering-matrix elements of a pair of PARCs operating at 1.25 and 5.3 GHz; (2) the design, construction, and performance evaluation of a PARC; and (3) the extension of the single-target-calibration technique (STCT) to a PARC. STCT has heretofore been limited to the use of reciprocal passive calibration devices, such as spheres and trihedral corner reflectors.

Fine structure of heliumlike ions and determination of the fine structure constant.

PubMed

Pachucki, Krzysztof; Yerokhin, Vladimir A

2010-02-19

We report a calculation of the fine-structure splitting in light heliumlike atoms, which accounts for all quantum electrodynamical effects up to order alpha{5} Ry. For the helium atom, we resolve the previously reported disagreement between theory and experiment and determine the fine-structure constant with an accuracy of 31 ppb. The calculational results are extensively checked by comparison with the experimental data for different nuclear charges and by evaluation of the hydrogenic limit of individual corrections.

Experimental demonstration of OSPF-TE extensions in muiti-domain OBS networks connected by GMPLS network

NASA Astrophysics Data System (ADS)

Tian, Chunlei; Yin, Yawei; Wu, Jian; Lin, Jintong

2008-11-01

The interworking network of Generalized Multi-Protocol Label Switching (GMPLS) and Optical Burst Switching (OBS) is attractive network architecture for the future IP/DWDM network nowadays. In this paper, OSPF-TE extensions for multi-domain Optical Burst Switching networks connected by GMPLS controlled WDM network are proposed, the corresponding experimental results such as the advertising latency are also presented by using an OBS network testbed. The experimental results show that it works effectively on the OBS/GMPLS networks.

Availability of Neutronics Benchmarks in the ICSBEP and IRPhEP Handbooks for Computational Tools Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bess, John D.; Briggs, J. Blair; Ivanova, Tatiana

2017-02-01

In the past several decades, numerous experiments have been performed worldwide to support reactor operations, measurements, design, and nuclear safety. Those experiments represent an extensive international investment in infrastructure, expertise, and cost, representing significantly valuable resources of data supporting past, current, and future research activities. Those valuable assets represent the basis for recording, development, and validation of our nuclear methods and integral nuclear data [1]. The loss of these experimental data, which has occurred all too much in the recent years, is tragic. The high cost to repeat many of these measurements can be prohibitive, if not impossible, to surmount.more » Two international projects were developed, and are under the direction of the Organisation for Co-operation and Development Nuclear Energy Agency (OECD NEA) to address the challenges of not just data preservation, but evaluation of the data to determine its merit for modern and future use. The International Criticality Safety Benchmark Evaluation Project (ICSBEP) was established to identify and verify comprehensive critical benchmark data sets; evaluate the data, including quantification of biases and uncertainties; compile the data and calculations in a standardized format; and formally document the effort into a single source of verified benchmark data [2]. Similarly, the International Reactor Physics Experiment Evaluation Project (IRPhEP) was established to preserve integral reactor physics experimental data, including separate or special effects data for nuclear energy and technology applications [3]. Annually, contributors from around the world continue to collaborate in the evaluation and review of select benchmark experiments for preservation and dissemination. The extensively peer-reviewed integral benchmark data can then be utilized to support nuclear design and safety analysts to validate the analytical tools, methods, and data needed for next-generation reactor design, safety analysis requirements, and all other front- and back-end activities contributing to the overall nuclear fuel cycle where quality neutronics calculations are paramount.« less

Nuclear Data Sheets for A = 139

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, Paresh K.; Singh, Balraj; Singh, Sukhjeet

2016-12-15

The experimental nuclear spectroscopic data for known nuclides of mass number 139 (Sn, Sb, Te, I, Xe, Cs, Ba, La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy) have been evaluated and presented together with adopted properties for levels and gamma rays. This evaluation represents a revision of previous one (2001Bu16) by T.W. Burrows. Since then extensive new data have become available for many A=139 nuclides although, no excited state data are yet available for {sup 139}Sn, {sup 139}Sb, {sup 139}Tb, and {sup 139}Dy. The decay schemes of {sup 139}Sn, {sup 139}Sb, {sup 139}I, {sup 139}Tb and {sup 139}Dymore » nuclei are not known, and those for {sup 139}Gd and {sup 139}Eu are poorly known. Particle-transfer data are available for {sup 139}Ba, {sup 139}La, {sup 139}Ce and {sup 139}Pr. Limited high-spin data are available for {sup 139}Te, {sup 139}I, {sup 139}Cs, {sup 139}Ba, {sup 139}La and {sup 139}Ce, while such data are extensive for {sup 139}Pr, {sup 139}Nd, {sup 139}Pm, {sup 139}Sm, {sup 139}Eu and {sup 139}Gd. Recent {sup 139}Pm high-spin data from two independent studies using the same reaction and similar beam energy are in conflict and could be improved using state-of-the-art large gamma-detector arrays in contrast to the smaller arrays currently used. Cases for which no new experimental information are available since the last update have undergone checking resulting in some changes in the current work, but for the most part these are taken from the previous evaluations. Thus, the present work has greatly benefited from all prior NDS evaluations (2001Bu16, 1989Bu12, 1981Pe04, 1974Gr46), but at the same time data presented herein supersede those in the earlier evaluations.« less

Experimental design matters for statistical analysis: how to handle blocking.

PubMed

Jensen, Signe M; Schaarschmidt, Frank; Onofri, Andrea; Ritz, Christian

2018-03-01

Nowadays, evaluation of the effects of pesticides often relies on experimental designs that involve multiple concentrations of the pesticide of interest or multiple pesticides at specific comparable concentrations and, possibly, secondary factors of interest. Unfortunately, the experimental design is often more or less neglected when analysing data. Two data examples were analysed using different modelling strategies. First, in a randomized complete block design, mean heights of maize treated with a herbicide and one of several adjuvants were compared. Second, translocation of an insecticide applied to maize as a seed treatment was evaluated using incomplete data from an unbalanced design with several layers of hierarchical sampling. Extensive simulations were carried out to further substantiate the effects of different modelling strategies. It was shown that results from suboptimal approaches (two-sample t-tests and ordinary ANOVA assuming independent observations) may be both quantitatively and qualitatively different from the results obtained using an appropriate linear mixed model. The simulations demonstrated that the different approaches may lead to differences in coverage percentages of confidence intervals and type 1 error rates, confirming that misleading conclusions can easily happen when an inappropriate statistical approach is chosen. To ensure that experimental data are summarized appropriately, avoiding misleading conclusions, the experimental design should duly be reflected in the choice of statistical approaches and models. We recommend that author guidelines should explicitly point out that authors need to indicate how the statistical analysis reflects the experimental design. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

A National Perspective on the Current Evaluation Activities in Extension

ERIC Educational Resources Information Center

Lamm, Alexa J.; Israel, Glenn D.; Diehl, David

2013-01-01

In order to enhance Extension evaluation efforts it is important to understand current practices. The study reported here researched the evaluation behaviors of county-based Extension professionals. Extension professionals from eight states (n = 1,173) responded to a survey regarding their evaluation data collection, analysis, and reporting…

Accurate green water loads calculation using naval hydro pack

NASA Astrophysics Data System (ADS)

Jasak, H.; Gatin, I.; Vukčević, V.

2017-12-01

An extensive verification and validation of Finite Volume based CFD software Naval Hydro based on foam-extend is presented in this paper for green water loads. Two-phase numerical model with advanced methods for treating the free surface is employed. Pressure loads on horizontal deck of Floating Production Storage and Offloading vessel (FPSO) model are compared to experimental results from [1] for three incident regular waves. Pressure peaks and integrals of pressure in time are measured on ten different locations on deck for each case. Pressure peaks and integrals are evaluated as average values among the measured incident wave periods, where periodic uncertainty is assessed for both numerical and experimental results. Spatial and temporal discretization refinement study is performed providing numerical discretization uncertainties.

Experimental demonstration of an OpenFlow based software-defined optical network employing packet, fixed and flexible DWDM grid technologies on an international multi-domain testbed.

PubMed

Channegowda, M; Nejabati, R; Rashidi Fard, M; Peng, S; Amaya, N; Zervas, G; Simeonidou, D; Vilalta, R; Casellas, R; Martínez, R; Muñoz, R; Liu, L; Tsuritani, T; Morita, I; Autenrieth, A; Elbers, J P; Kostecki, P; Kaczmarek, P

2013-03-11

Software defined networking (SDN) and flexible grid optical transport technology are two key technologies that allow network operators to customize their infrastructure based on application requirements and therefore minimizing the extra capital and operational costs required for hosting new applications. In this paper, for the first time we report on design, implementation & demonstration of a novel OpenFlow based SDN unified control plane allowing seamless operation across heterogeneous state-of-the-art optical and packet transport domains. We verify and experimentally evaluate OpenFlow protocol extensions for flexible DWDM grid transport technology along with its integration with fixed DWDM grid and layer-2 packet switching.

New Reactor Physics Benchmark Data in the March 2012 Edition of the IRPhEP Handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

John D. Bess; J. Blair Briggs; Jim Gulliford

2012-11-01

The International Reactor Physics Experiment Evaluation Project (IRPhEP) was established to preserve integral reactor physics experimental data, including separate or special effects data for nuclear energy and technology applications. Numerous experiments that have been performed worldwide, represent a large investment of infrastructure, expertise, and cost, and are valuable resources of data for present and future research. These valuable assets provide the basis for recording, development, and validation of methods. If the experimental data are lost, the high cost to repeat many of these measurements may be prohibitive. The purpose of the IRPhEP is to provide an extensively peer-reviewed set ofmore » reactor physics-related integral data that can be used by reactor designers and safety analysts to validate the analytical tools used to design next-generation reactors and establish the safety basis for operation of these reactors. Contributors from around the world collaborate in the evaluation and review of selected benchmark experiments for inclusion in the International Handbook of Evaluated Reactor Physics Benchmark Experiments (IRPhEP Handbook) [1]. Several new evaluations have been prepared for inclusion in the March 2012 edition of the IRPhEP Handbook.« less

Cutting the Wires: Modularization of Cellular Networks for Experimental Design

PubMed Central

Lang, Moritz; Summers, Sean; Stelling, Jörg

2014-01-01

Understanding naturally evolved cellular networks requires the consecutive identification and revision of the interactions between relevant molecular species. In this process, initially often simplified and incomplete networks are extended by integrating new reactions or whole subnetworks to increase consistency between model predictions and new measurement data. However, increased consistency with experimental data alone is not sufficient to show the existence of biomolecular interactions, because the interplay of different potential extensions might lead to overall similar dynamics. Here, we present a graph-based modularization approach to facilitate the design of experiments targeted at independently validating the existence of several potential network extensions. Our method is based on selecting the outputs to measure during an experiment, such that each potential network extension becomes virtually insulated from all others during data analysis. Each output defines a module that only depends on one hypothetical network extension, and all other outputs act as virtual inputs to achieve insulation. Given appropriate experimental time-series measurements of the outputs, our modules can be analyzed, simulated, and compared to the experimental data separately. Our approach exemplifies the close relationship between structural systems identification and modularization, an interplay that promises development of related approaches in the future. PMID:24411264

Effect of stretching program in an industrial workplace on hamstring flexibility and sagittal spinal posture of adult women workers: a randomized controlled trial.

PubMed

Muyor, José M; López-Miñarro, Pedro A; Casimiro, Antonio J

2012-01-01

To determine the effect of a stretching program performed in the workplace on the hamstring muscle extensibility and sagittal spinal posture of adult women. Fifty-eight adult women volunteers (mean age of 44.23 ± 8.87 years) from a private fruit and vegetable company were randomly assigned to experimental (n=27) or control (n=31) groups. The experimental group performed three exercises of hamstrings stretching of 20 seconds per exercise, three sessions a week for a period of 12 weeks. The control group did not participate in any hamstring stretching program. Hamstring flexibility was evaluated through the passive straight leg raise test and toe-touch test, performed both before and after the stretching program. Thoracic and lumbar curvatures and pelvic inclination were measured in relaxed standing and toe-touch test with a Spinal Mouse. Significant increases (p < 0.01) in toe-touch score and straight leg raise angle (in both legs) were found in the experimental group during post-test, while the control group showed a non-significant decrease for both toe-touch score and straight leg raise test. A significant decrease in thoracic curve and significant increase in pelvic inclination were found in the toe-touch test for the experimental group (p <0.05). However, no significant changes were found in standing posture for any group. Hamstring stretching exercises performed in the working place are effective for increasing hamstring muscle extensibility. This increase generates a more aligned thoracic curve and more anterior pelvic inclination when maximal trunk flexion is performed.

A Survey of Keystroke Dynamics Biometrics

PubMed Central

Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions. PMID:24298216

Optimizing Experimental Design for Comparing Models of Brain Function

PubMed Central

Daunizeau, Jean; Preuschoff, Kerstin; Friston, Karl; Stephan, Klaas

2011-01-01

This article presents the first attempt to formalize the optimization of experimental design with the aim of comparing models of brain function based on neuroimaging data. We demonstrate our approach in the context of Dynamic Causal Modelling (DCM), which relates experimental manipulations to observed network dynamics (via hidden neuronal states) and provides an inference framework for selecting among candidate models. Here, we show how to optimize the sensitivity of model selection by choosing among experimental designs according to their respective model selection accuracy. Using Bayesian decision theory, we (i) derive the Laplace-Chernoff risk for model selection, (ii) disclose its relationship with classical design optimality criteria and (iii) assess its sensitivity to basic modelling assumptions. We then evaluate the approach when identifying brain networks using DCM. Monte-Carlo simulations and empirical analyses of fMRI data from a simple bimanual motor task in humans serve to demonstrate the relationship between network identification and the optimal experimental design. For example, we show that deciding whether there is a feedback connection requires shorter epoch durations, relative to asking whether there is experimentally induced change in a connection that is known to be present. Finally, we discuss limitations and potential extensions of this work. PMID:22125485

Evaluation of fuel injection configurations to control carbon and soot formation in small GT combustors

NASA Technical Reports Server (NTRS)

Rosfjord, T. J.; Briehl, D.

1982-01-01

An experimental program to investigate hardware configurations which attempt to minimize carbon formation and soot production without sacrificing performance in small gas turbine combustors has been conducted at the United Technologies Research Center. Four fuel injectors, embodying either airblast atomization, pressure atomization, or fuel vaporization techniques, were combined with nozzle air swirlers and injector sheaths, and evaluated at test conditions which included and extended beyond standard small gas turbine combustor operation. Extensive testing was accomplished with configurations embodying either a spill return or a T-vaporizer injector. Minimal carbon deposits were observed on the spill return nozzle for tests using either Jet A or ERBS test fuel. A more extensive film of soft carbon was observed on the vaporizer after operation at standard engine conditions, with large carbonaceous growths forming on the device during off-design operation at low combustor inlet temperature. Test results indicated that smoke emission levels depended on the combustor fluid mechanics (especially the mixing rates near the injector), the atomization quality of the injector and the fuel hydrogen content.

Effects of a Stretching Development and Maintenance Program on Hamstring Extensibility in Schoolchildren: A Cluster-Randomized Controlled Trial

PubMed Central

Mayorga-Vega, Daniel; Merino-Marban, Rafael; Manzano-Lagunas, Jorge; Blanco, Humberto; Viciana, Jesús

2016-01-01

The main purpose of the present study was to examine the effects of a physical education-based stretching development and maintenance program on hamstring extensibility in schoolchildren. A sample of 150 schoolchildren aged 7-10 years old from a primary school participated in the present study (140 participants were finally included). The six classes balanced by grade were cluster randomly assigned to the experimental group 1 (n = 51), experimental group 2 (n = 51) or control group (n = 49) (i.e., a cluster randomized controlled trial design was used). During the physical education classes, the students from the experimental groups 1 and 2 performed a four-minute stretching program twice a week for nine weeks (first semester). Then, after a five-week period of detraining coinciding with the Christmas holidays, the students from the experimental groups 1 and 2 completed another stretching program twice a week for eleven weeks (second semester). The students from the experimental group 1 continued performing the stretching program for four minutes while those from the experimental group 2 completed a flexibility maintenance program for only one minute. The results of the two-way analysis of variance showed that the physical education-based stretching development program significantly improved the students’ hamstring extensibility (p < 0.001), as well as that these gains obtained remained after the stretching maintenance program (p < 0.001). Additionally, statistically significant differences between the two experimental groups were not found (p > 0.05). After a short-term stretching development program, a physical education-based stretching maintenance program of only one-minute sessions twice a week is effective in maintaining hamstring extensibility among schoolchildren. This knowledge could help and guide teachers to design programs that allow a feasible and effective development and maintenance of students’ flexibility in the physical education setting. Key points A physical education-based stretching maintenance program of only one-minute sessions twice a week is effective in maintaining hamstring extensibility among schoolchildren. A four-minute maintenance program shows similar effects that the one-minute maintenance program on hamstring extensibility among schoolchildren. Physical education teachers and other practitioners could carry out one-minute programs for a feasible and effective maintenance of students’ flexibility. PMID:26957928

Application of Crossover Design for Conducting Rigorous Extension Evaluations

ERIC Educational Resources Information Center

Jayaratne, K. S. U.; Bird, Carolyn L.; McClelland, Jacquelyn W.

2013-01-01

With the increasing demand for accountability of Extension programming, Extension professionals need to apply rigorous evaluation designs. Randomized designs are useful to eliminate selection biases of program participants and to improve the accuracy of evaluation. However, randomized control designs are not practical to apply in Extension program…

Characteristics of Human Brain Activity during the Evaluation of Service-to-Service Brand Extension

PubMed Central

Yang, Taeyang; Lee, Seungji; Seomoon, Eunbi; Kim, Sung-Phil

2018-01-01

Brand extension is a marketing strategy to apply the previously established brand name into new goods or service. A number of studies have reported the characteristics of human event-related potentials (ERPs) in response to the evaluation of goods-to-goods brand extension. In contrast, human brain responses to the evaluation of service extension are relatively unexplored. The aim of this study was investigating cognitive processes underlying the evaluation of service-to-service brand extension with electroencephalography (EEG). A total of 56 text stimuli composed of service brand name (S1) followed by extended service name (S2) were presented to participants. The EEG of participants was recorded while participants were asked to evaluate whether a given brand extension was acceptable or not. The behavioral results revealed that participants could evaluate brand extension though they had little knowledge about the extended services, indicating the role of brand in the evaluation of the services. Additionally, we developed a method of grouping brand extension stimuli according to the fit levels obtained from behavioral responses, instead of grouping of stimuli a priori. The ERP analysis identified three components during the evaluation of brand extension: N2, P300, and N400. No difference in the N2 amplitude was found among the different levels of a fit between S1 and S2. The P300 amplitude for the low level of fit was greater than those for higher levels (p < 0.05). The N400 amplitude was more negative for the mid- and high-level fits than the low level. The ERP results of P300 and N400 indicate that the early stage of brain extension evaluation might first detect low-fit brand extension as an improbable target followed by the late stage of the integration of S2 into S1. Along with previous findings, our results demonstrate different cognitive evaluation of service-to-service brand extension from goods-to-goods. PMID:29479313

Characteristics of Human Brain Activity during the Evaluation of Service-to-Service Brand Extension.

PubMed

Yang, Taeyang; Lee, Seungji; Seomoon, Eunbi; Kim, Sung-Phil

2018-01-01

Brand extension is a marketing strategy to apply the previously established brand name into new goods or service. A number of studies have reported the characteristics of human event-related potentials (ERPs) in response to the evaluation of goods-to-goods brand extension. In contrast, human brain responses to the evaluation of service extension are relatively unexplored. The aim of this study was investigating cognitive processes underlying the evaluation of service-to-service brand extension with electroencephalography (EEG). A total of 56 text stimuli composed of service brand name (S1) followed by extended service name (S2) were presented to participants. The EEG of participants was recorded while participants were asked to evaluate whether a given brand extension was acceptable or not. The behavioral results revealed that participants could evaluate brand extension though they had little knowledge about the extended services, indicating the role of brand in the evaluation of the services. Additionally, we developed a method of grouping brand extension stimuli according to the fit levels obtained from behavioral responses, instead of grouping of stimuli a priori . The ERP analysis identified three components during the evaluation of brand extension: N2, P300, and N400. No difference in the N2 amplitude was found among the different levels of a fit between S1 and S2. The P300 amplitude for the low level of fit was greater than those for higher levels ( p < 0.05). The N400 amplitude was more negative for the mid- and high-level fits than the low level. The ERP results of P300 and N400 indicate that the early stage of brain extension evaluation might first detect low-fit brand extension as an improbable target followed by the late stage of the integration of S2 into S1. Along with previous findings, our results demonstrate different cognitive evaluation of service-to-service brand extension from goods-to-goods.

Interactions between spacecraft motions and the atmospheric cloud physics laboratory experiments

NASA Technical Reports Server (NTRS)

Anderson, B. J.

1981-01-01

In evaluating the effects of spacecraft motions on atmospheric cloud physics laboratory (ACPL) experimentation, the motions of concern are those which will result in the movement of the fluid or cloud particles within the experiment chambers. Of the various vehicle motions and residual forces which can and will occur, three types appear most likely to damage the experimental results: non-steady rotations through a large angle, long-duration accelerations in a constant direction, and vibrations. During the ACPL ice crystal growth experiments, the crystals are suspended near the end of a long fiber (20 cm long by 200 micron diameter) of glass or similar material. Small vibrations of the supported end of the fiber could cause extensive motions of the ice crystal, if care is not taken to avoid this problem.

Advanced reservoir characterization and evaluation of CO{sub 2} gravity drainage in the naturally fractured Spraberry Trend Area, Class III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heckman, Tracy; Schechter, David S.

2000-04-11

The overall goal of this project was to assess the economic feasibility of CO{sub 2} flooding the naturally fractured Spraberry Trend Area in West Texas. This objective was accomplished by conducting research in four areas: (1) extensive characterization of the reservoirs, (2) experimental studies of crude oil/brine/rock (COBR) interaction in the reservoirs, (3) analytical and numerical simulation of Spraberry reservoirs, and, (4) experimental investigations on CO{sub 2} gravity drainage in Spraberry whole cores. This report provides results of the fourth year of the five-year project for each of the four areas including a status report of field activities leading upmore » to injection of CO{sub 2}.« less

Cross-species transmission of CWD prions.

PubMed

Kurt, Timothy D; Sigurdson, Christina J

2016-01-01

Prions cause fatal neurodegenerative diseases in humans and animals and can be transmitted zoonotically. Chronic wasting disease (CWD) is a highly transmissible prion disease of wild deer and elk that affects cervids over extensive regions of the United States and Canada. The risk of cross-species CWD transmission has been experimentally evaluated in a wide array of mammals, including non-human primates and mouse models expressing human cellular prion protein. Here we review the determinants of cross-species CWD transmission, and propose a model that may explain a structural barrier for CWD transmission to humans.

Fluid mass and thermal loading effects on the modal characteristics of space shuttle main engine liquid oxygen inlet splitter vanes

NASA Technical Reports Server (NTRS)

Panossian, H. V.; Boehnlein, J. J.

1987-01-01

An analysis and evaluation of experimental modal survey test data on the variations of modal characteristics induced by pressure and thermal loading events are presented. Extensive modal survey tests were carried out on a Space Shuttle Main Engine (SSME) test article using liquid nitrogen under cryogenic temperatures and high pressures. The results suggest that an increase of pressure under constant cryogenic temperature or a decrease of temperature under high pressure induces an upward shift of frequencies of various modes of the structures.

Evaluation of in-network adaptation of scalable high efficiency video coding (SHVC) in mobile environments

NASA Astrophysics Data System (ADS)

Nightingale, James; Wang, Qi; Grecos, Christos; Goma, Sergio

2014-02-01

High Efficiency Video Coding (HEVC), the latest video compression standard (also known as H.265), can deliver video streams of comparable quality to the current H.264 Advanced Video Coding (H.264/AVC) standard with a 50% reduction in bandwidth. Research into SHVC, the scalable extension to the HEVC standard, is still in its infancy. One important area for investigation is whether, given the greater compression ratio of HEVC (and SHVC), the loss of packets containing video content will have a greater impact on the quality of delivered video than is the case with H.264/AVC or its scalable extension H.264/SVC. In this work we empirically evaluate the layer-based, in-network adaptation of video streams encoded using SHVC in situations where dynamically changing bandwidths and datagram loss ratios require the real-time adaptation of video streams. Through the use of extensive experimentation, we establish a comprehensive set of benchmarks for SHVC-based highdefinition video streaming in loss prone network environments such as those commonly found in mobile networks. Among other results, we highlight that packet losses of only 1% can lead to a substantial reduction in PSNR of over 3dB and error propagation in over 130 pictures following the one in which the loss occurred. This work would be one of the earliest studies in this cutting-edge area that reports benchmark evaluation results for the effects of datagram loss on SHVC picture quality and offers empirical and analytical insights into SHVC adaptation to lossy, mobile networking conditions.

Cutting the wires: modularization of cellular networks for experimental design.

PubMed

Lang, Moritz; Summers, Sean; Stelling, Jörg

2014-01-07

Understanding naturally evolved cellular networks requires the consecutive identification and revision of the interactions between relevant molecular species. In this process, initially often simplified and incomplete networks are extended by integrating new reactions or whole subnetworks to increase consistency between model predictions and new measurement data. However, increased consistency with experimental data alone is not sufficient to show the existence of biomolecular interactions, because the interplay of different potential extensions might lead to overall similar dynamics. Here, we present a graph-based modularization approach to facilitate the design of experiments targeted at independently validating the existence of several potential network extensions. Our method is based on selecting the outputs to measure during an experiment, such that each potential network extension becomes virtually insulated from all others during data analysis. Each output defines a module that only depends on one hypothetical network extension, and all other outputs act as virtual inputs to achieve insulation. Given appropriate experimental time-series measurements of the outputs, our modules can be analyzed, simulated, and compared to the experimental data separately. Our approach exemplifies the close relationship between structural systems identification and modularization, an interplay that promises development of related approaches in the future. Copyright © 2014 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Practical Application of Aspiration as an Outcome Indicator in Extension Evaluation

ERIC Educational Resources Information Center

Jayaratne, K. S. U.

2010-01-01

Extension educators need simple and accurate evaluation tools for program evaluation. This article explains how to use aspiration as an outcome indicator in Extension evaluation and introduces a practical evaluation tool. Aspiration can be described as the readiness for change. By recording participants' levels of aspiration, we will be able to…

Nuclear Data Sheets for A = 192

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baglin, Coral M.

2012-08-15

Experimental structure and decay data for all nuclei with mass A=192 (Ta, W, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Po, At) have been evaluated. This evaluation, covering data received by 15 June 2012, supersedes the 1998 evaluation by C. M. Baglin (Nuclear Data Sheets84, 717 (1998), literature cutoff August 1998) and the subsequent inclusion in the ENSDF database of the new nuclide {sup 192}At (C. M. Baglin, literature cutoff 16 May 2006). It also incorporates the current evaluation of superdeformed-band information by B. Singh. Since the last publication, {sup 192}Ta, {sup 192}W and {sup 192}At have beenmore » observed, and an isomeric state has been identified in {sup 192}Re. The {epsilon} decay of {sup 192}Au has been studied using a multidetector array resulting in an extensively revised level scheme for {sup 192}Pt.« less

Extension of an assessment model of ship traffic exhaust emissions for particulate matter and carbon monoxide

NASA Astrophysics Data System (ADS)

Jalkanen, J.-P.; Johansson, L.; Kukkonen, J.; Brink, A.; Kalli, J.; Stipa, T.

2011-08-01

A method is presented for the evaluation of the exhaust emissions of marine traffic, based on the messages provided by the Automatic Identification System (AIS), which enable the positioning of ship emissions with a high spatial resolution (typically a few metres). The model also takes into account the detailed technical data of each individual vessel. The previously developed model was applicable for evaluating the emissions of NOx, SOx and CO2. This paper addresses a substantial extension of the modelling system, to allow also for the mass-based emissions of particulate matter (PM) and carbon monoxide (CO). The presented Ship Traffic Emissions Assessment Model (STEAM2) allows for the influences of accurate travel routes and ship speed, engine load, fuel sulphur content, multiengine setups, abatement methods and waves. We address in particular the modeling of the influence on the emissions of both engine load and the sulphur content of the fuel. The presented methodology can be used to evaluate the total PM emissions, and those of organic carbon, elemental carbon, ash and hydrated sulphate. We have evaluated the performance of the extended model against available experimental data on engine power, fuel consumption and the composition-resolved emissions of PM. As example results, the geographical distributions of the emissions of PM and CO are presented for the marine regions surrounding the Danish Straits.

IAEA CIELO Evaluation of Neutron-induced Reactions on 235U and 238U Targets

DOE PAGES

Capote, R.; Trkov, A.; Sin, M.; ...

2018-02-01

Evaluations of nuclear reaction data for the major uranium isotopes 238U and 235U were performed within the scope of the CIELO Project on the initiative of the OECD/NEA Data Bank under Working Party on Evaluation Co-operation (WPEC) Subgroup 40 coordinated by the IAEA Nuclear Data Section. Both the mean values and covariances are evaluated from 10 -5 eV up to 30 MeV. The resonance parameters of 238U and 235U were re-evaluated with the addition of newly available data to the existing experimental database. The evaluations in the fast neutron range are based on nuclear model calculations with the code EMPIRE–3.2more » Malta above the resonance range up to 30 MeV. 235U(n,f), 238U(n,f), and 238U(n,γ) cross sections and 235U(n th,f) prompt fission neutron spectrum (PFNS) were evaluated within the Neutron Standards project and are representative of the experimental state-of-the-art measurements. The Standards cross sections were matched in model calculations as closely as possible to guarantee a good predictive power for cross sections of competing neutron scattering channels. 235U(n,γ) cross section includes fluctuations observed in recent experiments. 235U(n,f) PFNS for incident neutron energies from 500 keV to 20 MeV were measured at Los Alamos Chi-Nu facility and re-evaluated using all available experimental data. While respecting the measured differential data, several compensating errors in previous evaluations were identified and removed so that the performance in integral benchmarks was restored or improved. Covariance matrices for 235U and 238U cross sections, angular distributions, spectra and neutron multiplicities were evaluated using the GANDR system that combines experimental data with model uncertainties. Unrecognized systematic uncertainties were considered in the uncertainty quantification for fission and capture cross sections above the thermal range, and for neutron multiplicities. Evaluated files were extensively benchmarked to ensure good performance in reactor calculations and fusion-related systems. New comprehensive evaluations show excellent agreement with available differential data and integral performance better than current evaluated data libraries, and represent a step forward in a quest for better nuclear data for applications.« less

IAEA CIELO Evaluation of Neutron-induced Reactions on 235U and 238U Targets

NASA Astrophysics Data System (ADS)

Capote, R.; Trkov, A.; Sin, M.; Pigni, M. T.; Pronyaev, V. G.; Balibrea, J.; Bernard, D.; Cano-Ott, D.; Danon, Y.; Daskalakis, A.; Goričanec, T.; Herman, M. W.; Kiedrowski, B.; Kopecky, S.; Mendoza, E.; Neudecker, D.; Leal, L.; Noguere, G.; Schillebeeckx, P.; Sirakov, I.; Soukhovitskii, E. S.; Stetcu, I.; Talou, P.

2018-02-01

Evaluations of nuclear reaction data for the major uranium isotopes 238U and 235U were performed within the scope of the CIELO Project on the initiative of the OECD/NEA Data Bank under Working Party on Evaluation Co-operation (WPEC) Subgroup 40 coordinated by the IAEA Nuclear Data Section. Both the mean values and covariances are evaluated from 10-5 eV up to 30 MeV. The resonance parameters of 238U and 235U were re-evaluated with the addition of newly available data to the existing experimental database. The evaluations in the fast neutron range are based on nuclear model calculations with the code EMPIRE-3.2 Malta above the resonance range up to 30 MeV. 235U(n,f), 238U(n,f), and 238U(n,γ) cross sections and 235U(nth,f) prompt fission neutron spectrum (PFNS) were evaluated within the Neutron Standards project and are representative of the experimental state-of-the-art measurements. The Standards cross sections were matched in model calculations as closely as possible to guarantee a good predictive power for cross sections of competing neutron scattering channels. 235U(n,γ) cross section includes fluctuations observed in recent experiments. 235U(n,f) PFNS for incident neutron energies from 500 keV to 20 MeV were measured at Los Alamos Chi-Nu facility and re-evaluated using all available experimental data. While respecting the measured differential data, several compensating errors in previous evaluations were identified and removed so that the performance in integral benchmarks was restored or improved. Covariance matrices for 235U and 238U cross sections, angular distributions, spectra and neutron multiplicities were evaluated using the GANDR system that combines experimental data with model uncertainties. Unrecognized systematic uncertainties were considered in the uncertainty quantification for fission and capture cross sections above the thermal range, and for neutron multiplicities. Evaluated files were extensively benchmarked to ensure good performance in reactor calculations and fusion-related systems. New comprehensive evaluations show excellent agreement with available differential data and integral performance better than current evaluated data libraries, and represent a step forward in a quest for better nuclear data for applications.

IAEA CIELO Evaluation of Neutron-induced Reactions on 235U and 238U Targets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Capote, R.; Trkov, A.; Sin, M.

Evaluations of nuclear reaction data for the major uranium isotopes 238U and 235U were performed within the scope of the CIELO Project on the initiative of the OECD/NEA Data Bank under Working Party on Evaluation Co-operation (WPEC) Subgroup 40 coordinated by the IAEA Nuclear Data Section. Both the mean values and covariances are evaluated from 10 -5 eV up to 30 MeV. The resonance parameters of 238U and 235U were re-evaluated with the addition of newly available data to the existing experimental database. The evaluations in the fast neutron range are based on nuclear model calculations with the code EMPIRE–3.2more » Malta above the resonance range up to 30 MeV. 235U(n,f), 238U(n,f), and 238U(n,γ) cross sections and 235U(n th,f) prompt fission neutron spectrum (PFNS) were evaluated within the Neutron Standards project and are representative of the experimental state-of-the-art measurements. The Standards cross sections were matched in model calculations as closely as possible to guarantee a good predictive power for cross sections of competing neutron scattering channels. 235U(n,γ) cross section includes fluctuations observed in recent experiments. 235U(n,f) PFNS for incident neutron energies from 500 keV to 20 MeV were measured at Los Alamos Chi-Nu facility and re-evaluated using all available experimental data. While respecting the measured differential data, several compensating errors in previous evaluations were identified and removed so that the performance in integral benchmarks was restored or improved. Covariance matrices for 235U and 238U cross sections, angular distributions, spectra and neutron multiplicities were evaluated using the GANDR system that combines experimental data with model uncertainties. Unrecognized systematic uncertainties were considered in the uncertainty quantification for fission and capture cross sections above the thermal range, and for neutron multiplicities. Evaluated files were extensively benchmarked to ensure good performance in reactor calculations and fusion-related systems. New comprehensive evaluations show excellent agreement with available differential data and integral performance better than current evaluated data libraries, and represent a step forward in a quest for better nuclear data for applications.« less

Taxonomy for Assessing Evaluation Competencies in Extension

ERIC Educational Resources Information Center

Rodgers, Michelle S.; Hillaker, Barbara D.; Haas, Bruce E.; Peters, Cheryl

2012-01-01

Evaluation of public service programming is becoming increasingly important with current funding realities. The taxonomy of evaluation competencies compiled by Ghere et al. (2006) provided the starting place for Taxonomy for Assessing Evaluation Competencies in Extension. The Michigan State University Extension case study described here presents a…

Experimental knee joint pain during strength training and muscle strength gain in healthy subjects: a randomized controlled trial.

PubMed

Sørensen, T J; Langberg, H; Hodges, P W; Bliddal, H; Henriksen, M

2012-01-01

Knee joint pain and reduced quadriceps strength are cardinal symptoms in many knee pathologies. In people with painful knee pathologies, quadriceps exercise reduces pain, improves physical function, and increases muscle strength. A general assumption is that pain compromises muscle function and thus may prevent effective rehabilitation. This study evaluated the effects of experimental knee joint pain during quadriceps strength training on muscle strength gain in healthy individuals. Twenty-seven healthy untrained volunteers participated in a randomized controlled trial of quadriceps strengthening (3 times per week for 8 weeks). Participants were randomized to perform resistance training either during pain induced by injections of painful hypertonic saline (pain group, n = 13) or during a nonpainful control condition with injection of isotonic saline (control group, n = 14) into the infrapatellar fat pad. The primary outcome measure was change in maximal isokinetic muscle strength in knee extension/flexion (60, 120, and 180 degrees/second). The group who exercised with pain had a significantly larger improvement in isokinetic muscle strength at all angular velocities of knee extension compared to the control group. In knee flexion there were improvements in isokinetic muscle strength in both groups with no between-group differences. Experimental knee joint pain improved the training-induced gain in muscle strength following 8 weeks of quadriceps training. It remains to be studied whether knee joint pain has a positive effect on strength gain in patients with knee pathology. Copyright © 2012 by the American College of Rheumatology.

Growth of Solid Solution Crystals

NASA Technical Reports Server (NTRS)

Lehoczky, S. L.; Szofran, F. R.; Holland, L. R.

1985-01-01

The major objective of this program is to determine the conditions under which single crystals of solid solutions can be grown from the melt in a Bridgman configuration with a high degree of chemical homogeneity. The central aim is to assess the role of gravity in the growth process and to explore the possible advantages for growth in the absence of gravity. The alloy system being investigated is the solid solution semiconductor with x-values appropriate for infrared detector applications in Hg sub (1-x) Cd sub x Te the 8 to 14 micro m wavelength region. Both melt and Te-solvent growth are being considered. The study consists of an extensive ground-based experimental and theoretical research effort followed by flight experimentation where appropriate. Experimental facilities have been established for the purification, casting, and crystal growth of the alloy system. Facilities have been also established for the metallurgical, compositional, electric and optical characterization of the alloys. Crystals are being grown by the Bridgman-Stockbarger method and are analyzed by various experimental techniques to evaluate the effects of growth conditions on the longitudinal and radial compositional variations and defect densities in the crystals.

Performance Evaluation of Large Aperture 'Polished Panel' Optical Receivers Based on Experimental Data

NASA Technical Reports Server (NTRS)

Vilnrotter, Victor

2013-01-01

Recent interest in hybrid RF/Optical communications has led to the development and installation of a "polished-panel" optical receiver evaluation assembly on the 34-meter research antenna at Deep-Space Station 13 (DSS-13) at NASA's Goldstone Communications Complex. The test setup consists of a custom aluminum panel polished to optical smoothness, and a large-sensor CCD camera designed to image the point-spread function (PSF) generated by the polished aluminum panel. Extensive data has been obtained via realtime tracking and imaging of planets and stars at DSS-13. Both "on-source" and "off-source" data were recorded at various elevations, enabling the development of realistic simulations and analytic models to help determine the performance of future deep-space communications systems operating with on-off keying (OOK) or pulse-position-modulated (PPM) signaling formats with photon-counting detection, and compared with the ultimate quantum bound on detection performance for these modulations. Experimentally determined PSFs were scaled to provide realistic signal-distributions across a photon-counting detector array when a pulse is received, and uncoded as well as block-coded performance analyzed and evaluated for a well-known class of block codes.

Evaluation of mechanical deformation and distributive magnetic loads with different mechanical constraints in two parallel conducting bars

NASA Astrophysics Data System (ADS)

Lee, Ho-Young; Lee, Se-Hee

2017-08-01

Mechanical deformation, bending deformation, and distributive magnetic loads were evaluated numerically and experimentally for conducting materials excited with high current. Until now, many research works have extensively studied the area of magnetic force and mechanical deformation by using coupled approaches such as multiphysics solvers. In coupled analysis for magnetoelastic problems, some articles and commercial software have presented the resultant mechanical deformation and stress on the body. To evaluate the mechanical deformation, the Lorentz force density method (LZ) and the Maxwell stress tensor method (MX) have been widely used for conducting materials. However, it is difficult to find any experimental verification regarding mechanical deformation or bending deformation due to magnetic force density. Therefore, we compared our numerical results to those from experiments with two parallel conducting bars to verify our numerical setup for bending deformation. Before showing this, the basic and interesting coupled simulation was conducted to test the mechanical deformations by the LZ (body force density) and the MX (surface force density) methods. This resulted in MX gave the same total force as LZ, but the local force distribution in MX introduced an incorrect mechanical deformation in the simulation of a solid conductor.

The SeaHorn Verification Framework

NASA Technical Reports Server (NTRS)

Gurfinkel, Arie; Kahsai, Temesghen; Komuravelli, Anvesh; Navas, Jorge A.

2015-01-01

In this paper, we present SeaHorn, a software verification framework. The key distinguishing feature of SeaHorn is its modular design that separates the concerns of the syntax of the programming language, its operational semantics, and the verification semantics. SeaHorn encompasses several novelties: it (a) encodes verification conditions using an efficient yet precise inter-procedural technique, (b) provides flexibility in the verification semantics to allow different levels of precision, (c) leverages the state-of-the-art in software model checking and abstract interpretation for verification, and (d) uses Horn-clauses as an intermediate language to represent verification conditions which simplifies interfacing with multiple verification tools based on Horn-clauses. SeaHorn provides users with a powerful verification tool and researchers with an extensible and customizable framework for experimenting with new software verification techniques. The effectiveness and scalability of SeaHorn are demonstrated by an extensive experimental evaluation using benchmarks from SV-COMP 2015 and real avionics code.

A replication and extension of the PEERS intervention: examining effects on social skills and social anxiety in adolescents with autism spectrum disorders.

PubMed

Schohl, Kirsten A; Van Hecke, Amy V; Carson, Audrey Meyer; Dolan, Bridget; Karst, Jeffrey; Stevens, Sheryl

2014-03-01

This study aimed to evaluate the Program for the Education and Enrichment of Relational Skills (PEERS: Laugeson et al. in J Autism Dev Disord 39(4):596-606, 2009). PEERS focuses on improving friendship quality and social skills among adolescents with higher-functioning ASD. 58 participants aged 11-16 years-old were randomly assigned to either an immediate treatment or waitlist comparison group. Results revealed, in comparison to the waitlist group, that the experimental treatment group significantly improved their knowledge of PEERS concepts and friendship skills, increased in their amount of get-togethers, and decreased in their levels of social anxiety, core autistic symptoms, and problem behaviors from pre-to post-PEERS. This study provides the first independent replication and extension of the empirically-supported PEERS social skills intervention for adolescents with ASD.

Target Fishing for Chemical Compounds using Target-Ligand Activity data and Ranking based Methods

PubMed Central

Wale, Nikil; Karypis, George

2009-01-01

In recent years the development of computational techniques that identify all the likely targets for a given chemical compound, also termed as the problem of Target Fishing, has been an active area of research. Identification of likely targets of a chemical compound helps to understand problems such as toxicity, lack of efficacy in humans, and poor physical properties associated with that compound in the early stages of drug discovery. In this paper we present a set of techniques whose goal is to rank or prioritize targets in the context of a given chemical compound such that most targets that this compound may show activity against appear higher in the ranked list. These methods are based on our extensions to the SVM and Ranking Perceptron algorithms for this problem. Our extensive experimental study shows that the methods developed in this work outperform previous approaches by 2% to 60% under different evaluation criterions. PMID:19764745

Fusible heat sink materials - Evaluation of alternate candidates. [for PLSS cooling systems

NASA Technical Reports Server (NTRS)

Selvaduray, Guna S.; Lomax, W. C.

1992-01-01

Fusible heat sinks are a possible source for thermal regulation of space suited astronauts. Materials with greater thermal storage capability than water could enable both an extension of time between recharging and/or a reduction in size and/or mass. An extensive literature search identified 1,215 candidates with a solid-liquid transformation within the temperature range of -13 C to 5 C. Based on data available in the literature, several candidates with a cooling capacity significantly greater than water were identified. Measurements of the transformation temperature and enthalpy of transformation were then undertaken with a differential scanning calorimeter in order to confirm the accuracy of the literature. Laboratory measurements have thus far not been able to corroborate the extremely high values found from the literature. This paper presents the approach for materials selection utilized in this study, the experimental procedure, and the results of the measurements thus far undertaken.

Evaluation of homogeneous electrocatalysts by cyclic voltammetry.

PubMed

Rountree, Eric S; McCarthy, Brian D; Eisenhart, Thomas T; Dempsey, Jillian L

2014-10-06

The pursuit of solar fuels has motivated extensive research on molecular electrocatalysts capable of evolving hydrogen from protic solutions, reducing CO2, and oxidizing water. Determining accurate figures of merit for these catalysts requires the careful and appropriate application of electroanalytical techniques. This Viewpoint first briefly presents the fundamentals of cyclic voltammetry and highlights practical experimental considerations before focusing on the application of cyclic voltammetry for the characterization of electrocatalysts. Key metrics for comparing catalysts, including the overpotential (η), potential for catalysis (E(cat)), observed rate constant (k(obs)), and potential-dependent turnover frequency, are discussed. The cyclic voltammetric responses for a general electrocatalytic one-electron reduction of a substrate are presented along with methods to extract figures of merit from these data. The extension of this analysis to more complex electrocatalytic schemes, such as those responsible for H2 evolution and CO2 reduction, is then discussed.

Evaluation in Extension.

ERIC Educational Resources Information Center

Byrn, Darcie; And Others

The authors have written this manual to aid workers in the Cooperative Extension Service of the United States to be better able to understand and apply the principles and methods of evaluation. The manual contains three sections which cover the nature and place of evaluation in extension work, the evaluation process, and the uses of evaluation…

Tools for Formative Evaluation: Gathering the Information Necessary for Program Improvement

ERIC Educational Resources Information Center

Jayaratne, K. S. U.

2016-01-01

New Extension educators experience a steep learning curve when attempting to develop effective Extension programs. Formative evaluation is helpful to new, and experienced, Extension educators in determining the changes necessary for making programs more effective. Formative evaluation is an essential part of program evaluation. However, its use…

Twitter Chats: Connect, Foster, and Engage Internal Extension Networks

ERIC Educational Resources Information Center

Seger, Jamie; Hill, Paul; Stafne, Eric; Swadley, Emy

2017-01-01

The eXtension Educational Technology Learning Network (EdTechLN) has found Twitter to be an effective form of informal communication for routinely engaging network members. Twitter chats provide Extension professionals an opportunity to reach and engage one other. As the EdTechLN's experimentation with Twitter chats has demonstrated, the use of…

Metabonomics approaches and the potential application in foodsafety evaluation.

PubMed

Kuang, Hua; Li, Zhe; Peng, Chifang; Liu, Liqiang; Xu, Liguang; Zhu, Yingyue; Wang, Libing; Xu, Chuanlai

2012-01-01

It is essential that the novel biomarkers discovered by means of advanced detection tools based on metabonomics could be used for long-term monitoring in food safety. By summarizing the common biomarkers discovery flowsheet based on metabonomics, this review evaluates the possible application of metabonomics in new biomarker discovery, especially in relation to food safety issues. Metabonomics have the advantages of decreasing detection limits and constant monitoring. Although metabonomics is still in the developmental stage, we believe that, based on its properties, such as noninvasiveness, sensitivity, and persistence, together with rigorous experimental designs, new and novel technologies, as well as increasingly accurate chemometrics and a relational database, metabonomics can demonstrate extensive application in food safety in the postgenome period.

An Extended Damage Plasticity Model for Shotcrete: Formulation and Comparison with Other Shotcrete Models

PubMed Central

Neuner, Matthias; Gamnitzer, Peter; Hofstetter, Günter

2017-01-01

The aims of the present paper are (i) to briefly review single-field and multi-field shotcrete models proposed in the literature; (ii) to propose the extension of a damage-plasticity model for concrete to shotcrete; and (iii) to evaluate the capabilities of the proposed extended damage-plasticity model for shotcrete by comparing the predicted response with experimental data for shotcrete and with the response predicted by shotcrete models, available in the literature. The results of the evaluation will be used for recommendations concerning the application and further improvements of the investigated shotcrete models and they will serve as a basis for the design of a new lab test program, complementing the existing ones. PMID:28772445

Impacts of exposure to images of ideal bodies on male body dissatisfaction: a review.

PubMed

Blond, Anna

2008-09-01

Research suggests that young men's body dissatisfaction increases when they see images of attractive muscular men. This article provides the first extensive review of experimental studies exposing men to advertisements or commercials featuring idealized male bodies. Impacts on body dissatisfaction were evaluated by calculating and analyzing effect sizes from 15 studies. The effect sizes indicate that exposure to images of idealized male bodies has a small but statistically significant negative impact on men's body dissatisfaction. Three studies suggest that young men who are dissatisfied with their bodies are at increased risk for negative self-evaluations when exposed to idealized images. Two studies suggest that men who are satisfied with their bodies may be protected against negative impacts from seeing such images.

A model for growth of a single fungal hypha based on well-mixed tanks in series: simulation of nutrient and vesicle transport in aerial reproductive hyphae.

PubMed

Balmant, Wellington; Sugai-Guérios, Maura Harumi; Coradin, Juliana Hey; Krieger, Nadia; Furigo Junior, Agenor; Mitchell, David Alexander

2015-01-01

Current models that describe the extension of fungal hyphae and development of a mycelium either do not describe the role of vesicles in hyphal extension or do not correctly describe the experimentally observed profile for distribution of vesicles along the hypha. The present work uses the n-tanks-in-series approach to develop a model for hyphal extension that describes the intracellular transport of nutrient to a sub-apical zone where vesicles are formed and then transported to the tip, where tip extension occurs. The model was calibrated using experimental data from the literature for the extension of reproductive aerial hyphae of three different fungi, and was able to describe different profiles involving acceleration and deceleration of the extension rate. A sensitivity analysis showed that the supply of nutrient to the sub-apical vesicle-producing zone is a key factor influencing the rate of extension of the hypha. Although this model was used to describe the extension of a single reproductive aerial hypha, the use of the n-tanks-in-series approach to representing the hypha means that the model has the flexibility to be extended to describe the growth of other types of hyphae and the branching of hyphae to form a complete mycelium.

Experimental evaluation of the extended Dytlewski-style dead time correction formalism for neutron multiplicity counting

NASA Astrophysics Data System (ADS)

Lockhart, M.; Henzlova, D.; Croft, S.; Cutler, T.; Favalli, A.; McGahee, Ch.; Parker, R.

2018-01-01

Over the past few decades, neutron multiplicity counting has played an integral role in Special Nuclear Material (SNM) characterization pertaining to nuclear safeguards. Current neutron multiplicity analysis techniques use singles, doubles, and triples count rates because a methodology to extract and dead time correct higher order count rates (i.e. quads and pents) was not fully developed. This limitation is overcome by the recent extension of a popular dead time correction method developed by Dytlewski. This extended dead time correction algorithm, named Dytlewski-Croft-Favalli(DCF), is detailed in reference Croft and Favalli (2017), which gives an extensive explanation of the theory and implications of this new development. Dead time corrected results can then be used to assay SNM by inverting a set of extended point model equations which as well have only recently been formulated. The current paper discusses and presents the experimental evaluation of practical feasibility of the DCF dead time correction algorithm to demonstrate its performance and applicability in nuclear safeguards applications. In order to test the validity and effectiveness of the dead time correction for quads and pents, 252Cf and SNM sources were measured in high efficiency neutron multiplicity counters at the Los Alamos National Laboratory (LANL) and the count rates were extracted up to the fifth order and corrected for dead time. In order to assess the DCF dead time correction, the corrected data is compared to traditional dead time correction treatment within INCC. The DCF dead time correction is found to provide adequate dead time treatment for broad range of count rates available in practical applications.

A Model for Evaluating eXtension Communities of Practice

ERIC Educational Resources Information Center

Kelsey, Kathleen D.; Stafne, Eric T.

2012-01-01

As Americans shift their work and leisure activities online, Extension seeks to remain viable by delivering programs through a website known as eXtension. eXtension is predicated on the voluntary labor of Extension specialists and educators who form Communities of Practice to create and deliver content through the website. Evaluation of eXtension…

Stochastic Time Models of Syllable Structure

PubMed Central

Shaw, Jason A.; Gafos, Adamantios I.

2015-01-01

Drawing on phonology research within the generative linguistics tradition, stochastic methods, and notions from complex systems, we develop a modelling paradigm linking phonological structure, expressed in terms of syllables, to speech movement data acquired with 3D electromagnetic articulography and X-ray microbeam methods. The essential variable in the models is syllable structure. When mapped to discrete coordination topologies, syllabic organization imposes systematic patterns of variability on the temporal dynamics of speech articulation. We simulated these dynamics under different syllabic parses and evaluated simulations against experimental data from Arabic and English, two languages claimed to parse similar strings of segments into different syllabic structures. Model simulations replicated several key experimental results, including the fallibility of past phonetic heuristics for syllable structure, and exposed the range of conditions under which such heuristics remain valid. More importantly, the modelling approach consistently diagnosed syllable structure proving resilient to multiple sources of variability in experimental data including measurement variability, speaker variability, and contextual variability. Prospects for extensions of our modelling paradigm to acoustic data are also discussed. PMID:25996153

Histological evaluation of direct pulp capping of rat pulp with experimentally developed low-viscosity adhesives containing reparative dentin-promoting agents.

PubMed

Suzuki, Masaya; Taira, Yoshihisa; Kato, Chikage; Shinkai, Koichi; Katoh, Yoshiroh

2016-01-01

This study examines the wound healing process in exposed rat pulp when capped with experimental adhesive resin systems. Experimental adhesive resin system for direct pulp capping was composed of primer-I (PI), -II (PII), and -III (PIII) and an experimental bonding agent (EBA). PI was Clearfil(®) SE Bond(®)/Primer (CSP) containing 5.0 wt% CaCl2, PII was PI containing 10 wt% nanofiller (Aerosil(®) 380), and PIII was CSP containing 5.0 wt% of compounds of equal moles of synthetic peptides (pA and pB) derived from dentin matrix protein 1. EBA was Clearfil(®) SE Bond(®)/Bond (CSB) containing 10 wt% hydroxyapatite powders. Three experimental groups were designed. PI was assigned to experimental Groups 1 and 3. PII was assigned to experimental Groups 2 and 3. PIII and EBA were assigned to all experimental adhesive groups. Control teeth were capped with calcium hydroxide preparation (Dycal(®)), and CSP and CSB were applied to the cavity. The rats were sacrificed after each observation period (14, 28, 56, and 112 days). The following parameters were evaluated: pulp tissue disorganization, inflammatory cell infiltration, reparative dentin formation (RDF), and bacterial penetration. There were no significant differences among all the groups for all parameters and all observation periods (p>0.05, Kruskal-Wallis test). All groups showed initial RDF at 14 days postoperatively and extensive RDF until 112 days postoperatively. Groups 2 and 3 demonstrated higher quantity of mineralized dentin bridge formation compared with Group 1. Addition of nanofillers to the primer was effective in promoting high-density RDF. Experimentally developed adhesive resin systems induce the exposed pulp to produce almost the same quantity of reparative dentin as calcium hydroxide. However, we need further studies to elucidate whether the same results could be obtained in humans. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evaluating performance of containment equipment designed for handling manufactured nanomaterials by use of nanoparticle tracer

NASA Astrophysics Data System (ADS)

Artous, Sébastien; Bombardier, Pierre; Derrough, Samir; Locatelli, Dominique; Nobile, Pierre; Durand, Catherine

2013-04-01

The implementation in many products of manufactured nanoparticles is in strong growth and raises new questions. For this purpose, the CEA - NanoSafety Platform is developing various research topics for health and safety, environment and nanoparticles exposure in professional activities. The working group Nano-CERT/MTD, driven by INERIS, federates actors of the sector: experts, research organizations, industrial users and manufacturers of collective protection. The main activity of this group is to establish specific guidelines or a voluntary certification of collective protection, at a national scale, but with the possibility of a further extension at an European level. The group aims to establish an experimental protocol of certification to characterize collective protections for workers faced with nanomaterials potential exposure. The NanoSafety Platform provides in this presentation a method of collective protection characterization based on the developments in nanoparticles metrology and on the study of existing standards and practices in related areas (chemicals, dust, microbiological and nuclear). This study presents the results obtained during the experimental characterization of a potential nanoparticles transfer in a prototype laboratory fume hood by the use of a particulate tracer of sodium-fluorescein. The efficiency of the equipment and more specifically the efficiency of dynamical air barrier is evaluated, with the experimental results, by calculating the backward diffusion coefficient.

Tracking a Non-Cooperative Target Using Real-Time Stereovision-Based Control: An Experimental Study.

PubMed

Shtark, Tomer; Gurfil, Pini

2017-03-31

Tracking a non-cooperative target is a challenge, because in unfamiliar environments most targets are unknown and unspecified. Stereovision is suited to deal with this issue, because it allows to passively scan large areas and estimate the relative position, velocity and shape of objects. This research is an experimental effort aimed at developing, implementing and evaluating a real-time non-cooperative target tracking methods using stereovision measurements only. A computer-vision feature detection and matching algorithm was developed in order to identify and locate the target in the captured images. Three different filters were designed for estimating the relative position and velocity, and their performance was compared. A line-of-sight control algorithm was used for the purpose of keeping the target within the field-of-view. Extensive analytical and numerical investigations were conducted on the multi-view stereo projection equations and their solutions, which were used to initialize the different filters. This research shows, using an experimental and numerical evaluation, the benefits of using the unscented Kalman filter and the total least squares technique in the stereovision-based tracking problem. These findings offer a general and more accurate method for solving the static and dynamic stereovision triangulation problems and the concomitant line-of-sight control.

Tracking a Non-Cooperative Target Using Real-Time Stereovision-Based Control: An Experimental Study

PubMed Central

Shtark, Tomer; Gurfil, Pini

2017-01-01

Tracking a non-cooperative target is a challenge, because in unfamiliar environments most targets are unknown and unspecified. Stereovision is suited to deal with this issue, because it allows to passively scan large areas and estimate the relative position, velocity and shape of objects. This research is an experimental effort aimed at developing, implementing and evaluating a real-time non-cooperative target tracking methods using stereovision measurements only. A computer-vision feature detection and matching algorithm was developed in order to identify and locate the target in the captured images. Three different filters were designed for estimating the relative position and velocity, and their performance was compared. A line-of-sight control algorithm was used for the purpose of keeping the target within the field-of-view. Extensive analytical and numerical investigations were conducted on the multi-view stereo projection equations and their solutions, which were used to initialize the different filters. This research shows, using an experimental and numerical evaluation, the benefits of using the unscented Kalman filter and the total least squares technique in the stereovision-based tracking problem. These findings offer a general and more accurate method for solving the static and dynamic stereovision triangulation problems and the concomitant line-of-sight control. PMID:28362338

Simulation of Constrained Musculoskeletal Systems in Task Space.

PubMed

Stanev, Dimitar; Moustakas, Konstantinos

2018-02-01

This paper proposes an operational task space formalization of constrained musculoskeletal systems, motivated by its promising results in the field of robotics. The change of representation requires different algorithms for solving the inverse and forward dynamics simulation in the task space domain. We propose an extension to the direct marker control and an adaptation of the computed muscle control algorithms for solving the inverse kinematics and muscle redundancy problems, respectively. Experimental evaluation demonstrates that this framework is not only successful in dealing with the inverse dynamics problem, but also provides an intuitive way of studying and designing simulations, facilitating assessment prior to any experimental data collection. The incorporation of constraints in the derivation unveils an important extension of this framework toward addressing systems that use absolute coordinates and topologies that contain closed kinematic chains. Task space projection reveals a more intuitive encoding of the motion planning problem, allows for better correspondence between observed and estimated variables, provides the means to effectively study the role of kinematic redundancy, and most importantly, offers an abstract point of view and control, which can be advantageous toward further integration with high level models of the precommand level. Task-based approaches could be adopted in the design of simulation related to the study of constrained musculoskeletal systems.

Evaluation of methods for rapid determination of freezing point of aviation fuels

NASA Technical Reports Server (NTRS)

Mathiprakasam, B.

1982-01-01

Methods for identification of the more promising concepts for the development of a portable instrument to rapidly determine the freezing point of aviation fuels are described. The evaluation process consisted of: (1) collection of information on techniques previously used for the determination of the freezing point, (2) screening and selection of these techniques for further evaluation of their suitability in a portable unit for rapid measurement, and (3) an extensive experimental evaluation of the selected techniques and a final selection of the most promising technique. Test apparatuses employing differential thermal analysis and the change in optical transparency during phase change were evaluated and tested. A technique similar to differential thermal analysis using no reference fuel was investigated. In this method, the freezing point was obtained by digitizing the data and locating the point of inflection. Results obtained using this technique compare well with those obtained elsewhere using different techniques. A conceptual design of a portable instrument incorporating this technique is presented.

Universal odd-even staggering in isotopic fragmentation and spallation cross sections of neutron-rich fragments

NASA Astrophysics Data System (ADS)

Mei, B.; Tu, X. L.; Wang, M.

2018-04-01

An evident odd-even staggering (OES) in fragment cross sections has been experimentally observed in many fragmentation and spallation reactions. However, quantitative comparisons of this OES effect in different reaction systems are still scarce for neutron-rich nuclei near the neutron drip line. By employing a third-order difference formula, the magnitudes of this OES in extensive experimental cross sections are systematically investigated for many neutron-rich nuclei with (N -Z ) from 1 to 23 over a broad range of atomic numbers (Z ≈3 -50 ). A comparison of these magnitude values extracted from fragment cross sections measured in different fragmentation and spallation reactions with a large variety of projectile-target combinations over a wide energy range reveals that the OES magnitude is almost independent of the projectile-target combinations and the projectile energy. The weighted average of these OES magnitudes derived from cross sections accurately measured in different reaction systems is adopted as the evaluation value of the OES magnitude. These evaluated OES magnitudes are recommended to be used in fragmentation and spallation models to improve their predictions for fragment cross sections.

Non-formal educator use of evaluation results.

PubMed

Baughman, Sarah; Boyd, Heather H; Franz, Nancy K

2012-08-01

Increasing demands for accountability in educational programming have resulted in increasing calls for program evaluation in educational organizations. Many organizations include conducting program evaluations as part of the job responsibilities of program staff. Cooperative Extension is a complex organization offering non-formal educational programs through land grant universities. Many Extension services require non-formal educational program evaluations be conducted by field-based Extension educators. Evaluation research has focused primarily on the efforts of professional, external evaluators. The work of program staff with many responsibilities including program evaluation has received little attention. This study examined how field based Extension educators (i.e. program staff) in four Extension services use the results of evaluations of programs that they have conducted themselves. Four types of evaluation use are measured and explored; instrumental use, conceptual use, persuasive use and process use. Results indicate that there are few programmatic changes as a result of evaluation findings among the non-formal educators surveyed in this study. Extension educators tend to use evaluation results to persuade others about the value of their programs and learn from the evaluation process. Evaluation use is driven by accountability measures with very little program improvement use as measured in this study. Practical implications include delineating accountability and program improvement tasks within complex organizations in order to align evaluation efforts and to improve the results of both. There is some evidence that evaluation capacity building efforts may be increasing instrumental use by educators evaluating their own programs. Copyright © 2011 Elsevier Ltd. All rights reserved.

Do cervical collars and cervicothoracic orthoses effectively stabilize the injured cervical spine? A biomechanical investigation.

PubMed

Ivancic, Paul C

2013-06-01

In vitro biomechanical study. Our objective was to determine the effectiveness of cervical collars and cervicothoracic orthoses for stabilizing clinically relevant, experimentally produced cervical spine injuries. Most previous in vitro studies of cervical orthoses used a simplified injury model with all ligaments transected at a single spinal level, which differs from real-life neck injuries. Human volunteer studies are limited to measuring only sagittal motions or 3-dimensional motions only of the head or 1 or 2 spinal levels. Three-plane flexibility tests were performed to evaluate 2 cervical collars (Vista Collar and Vista Multipost Collar) and 2 cervicothoracic orthoses (Vista TS and Vista TS4) using a skull-neck-thorax model with 8 injured cervical spine specimens (manufacturer of orthoses: Aspen Medical Products Inc, Irvine, CA). The injuries consisted of flexion-compression at the lower cervical spine and extension-compression at superior spinal levels. Pair-wise repeated measures analysis of variance (P < 0.05) and Bonferroni post hoc tests determined significant differences in average range of motions of the head relative to the base, C7 or T1, among experimental conditions. RESULTS.: All orthoses significantly reduced unrestricted head/base flexion and extension. The orthoses allowed between 8.4% and 25.8% of unrestricted head/base motion in flexion/extension, 57.8% to 75.5% in axial rotation, and 53.8% to 73.7% in lateral bending. The average percentages of unrestricted motion allowed by the Vista Collar, Vista Multipost Collar, Vista TS, and Vista TS4 were: 14.0, 9.7, 6.1, and 4.7, respectively, for middle cervical spine extension and 13.2, 11.8, 3.3, and 0.4, respectively, for lower cervical spine flexion. Successive increases in immobilization were observed from Vista Collar to Vista Multipost Collar, Vista TS, and Vista TS4 in extension at the injured middle cervical spine and in flexion at the injured lower cervical spine. Our results may assist clinicians in selecting the most appropriate orthosis based upon patient-specific cervical spine injuries.

Extension of applicable neutron energy of DARWIN up to 1 GeV.

PubMed

Satoh, D; Sato, T; Endo, A; Matsufuji, N; Takada, M

2007-01-01

The radiation-dose monitor, DARWIN, needs a set of response functions of the liquid organic scintillator to assess a neutron dose. SCINFUL-QMD is a Monte Carlo based computer code to evaluate the response functions. In order to improve the accuracy of the code, a new light-output function based on the experimental data was developed for the production and transport of protons deuterons, tritons, (3)He nuclei and alpha particles, and incorporated into the code. The applicable energy of DARWIN was extended to 1 GeV using the response functions calculated by the modified SCINFUL-QMD code.

Aeroacoustics of Flight Vehicles: Theory and Practice. Volume 1: Noise Sources

NASA Technical Reports Server (NTRS)

Hubbard, Harvey H. (Editor)

1991-01-01

Methodology recommended to evaluate aeroacoustic related problems is provided, and approaches to their solutions are suggested without extensive tables, nomographs, and derivations. Orientation is toward flight vehicles and emphasis is on underlying physical concepts. Theoretical, experimental, and applied aspects are covered, including the main formulations and comparisons of theory and experiment. The topics covered include: propeller and propfan noise, rotor noise, turbomachinery noise, jet noise classical theory and experiments, noise from turbulent shear flows, jet noise generated by large-scale coherent motion, airframe noise, propulsive lift noise, combustion and core noise, and sonic booms.

Experimental study of delta wing leading-edge devices for drag reduction at high lift

NASA Technical Reports Server (NTRS)

Johnson, T. D., Jr.; Rao, D. M.

1982-01-01

The drag reduction devices selected for evaluation were the fence, slot, pylon-type vortex generator, and sharp leading-edge extension. These devices were tested on a 60 degree flatplate delta (with blunt leading edges) in the Langley Research Center 7- by 10-foot high-speed tunnel at low speed and to angles of attack of 28 degrees. Balance and static pressure measurements were taken. The results indicate that all the devices had significant drag reduction capability and improved longitudinal stability while a slight loss of lift and increased cruise drag occurred.

Hormone purification by isoelectric focusing in space

NASA Technical Reports Server (NTRS)

Bier, M.

1982-01-01

The performance of a ground-prototype of an apparatus for recycling isoelectric focusing was evaluated in an effort to provide technology for large scale purification of peptide hormones, proteins, and other biologicals. Special emphasis was given to the effects of gravity on the function of the apparatus and to the determination of potential advantages deriveable from its use in a microgravity environment. A theoretical model of isoelectric focusing sing chemically defined buffer systems for the establishment of the pH gradients was developed. The model was transformed to a form suitable for computer simulations and was used extensively for the design of experimental buffers.

Nuclear Data Sheets for A=85

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, Balraj; Chen, Jun

2014-02-01

Evaluated experimental data are presented for 13 known nuclides of mass 85 (Zn, Ga, Ge, As, Se, Br, Kr, Rb, Sr, Y, Zr, Nb, Mo). Since the previous 1990 evaluation of A=85, {sup 85}Zn, {sup 85}Ga, {sup 85}Ge and {sup 85}nuclides are newly added here. Excited state data for {sup 85}Se, {sup 85}Zr have become available from radioactive decay and in–beam γ–ray studies. New and improved high–spin data are available for {sup 85}Br, {sup 85}Kr, {sup 85}Rb, {sup 85}Y, {sup 85}Nb and {sup 85}Mo. New direct and precise measurement of atomic masses of {sup 85}Ge, {sup 85}As, {sup 85}Se, {supmore » 85}Br, {sup 85}Rb, {sup 85}Zr, {sup 85}Nb and {sup 85}Mo have greatly improved the landscape of β decay–Q values and separation energies in this mass region. In spite of extensive experimental work on the isobaric nuclei of this mass chain several deficiencies remain. No excited states are known in {sup 85}Zn, {sup 85}Ga, {sup 85}As. Only a few excited state are assigned in {sup 85}Ge from {sup 85}Ga β– decay. From radioactivity studies, the decay schemes of {sup 85}Zn and {sup 85}Mo are not known, and those for {sup 85}Ga, {sup 85}Ge, {sup 85}As and 10.9–s isomer of {sup 85}Zr are incomplete. Level lifetimes are not known for excited states in {sup 85}Se, {sup 85}Br, {sup 85}Nb and {sup 85}Mo. The {sup 85}Tc nuclide has not been detected in fragmentation experiments at GANIL, alluding to its unbound nature for proton emission. The {sup 85}Kr, {sup 85}Rb, {sup 85}Sr, and {sup 85}Y nuclides remain the most extensively studied from many different reactions and decays. The evaluation of A=85 nuclides has been done after a span of 23 years, thus includes an extensive amount of new data for almost each nuclide. This work supersedes the data for A=85 nuclides presented in earlier full NDS publication by J. Tepel in 1980Te04 and a later one published in an update mode by H. Sievers in 1991Si01.« less

A Model for Growth of a Single Fungal Hypha Based on Well-Mixed Tanks in Series: Simulation of Nutrient and Vesicle Transport in Aerial Reproductive Hyphae

PubMed Central

Balmant, Wellington; Sugai-Guérios, Maura Harumi; Coradin, Juliana Hey; Krieger, Nadia; Furigo Junior, Agenor; Mitchell, David Alexander

2015-01-01

Current models that describe the extension of fungal hyphae and development of a mycelium either do not describe the role of vesicles in hyphal extension or do not correctly describe the experimentally observed profile for distribution of vesicles along the hypha. The present work uses the n-tanks-in-series approach to develop a model for hyphal extension that describes the intracellular transport of nutrient to a sub-apical zone where vesicles are formed and then transported to the tip, where tip extension occurs. The model was calibrated using experimental data from the literature for the extension of reproductive aerial hyphae of three different fungi, and was able to describe different profiles involving acceleration and deceleration of the extension rate. A sensitivity analysis showed that the supply of nutrient to the sub-apical vesicle-producing zone is a key factor influencing the rate of extension of the hypha. Although this model was used to describe the extension of a single reproductive aerial hypha, the use of the n-tanks-in-series approach to representing the hypha means that the model has the flexibility to be extended to describe the growth of other types of hyphae and the branching of hyphae to form a complete mycelium. PMID:25785863

Display/control requirements for automated VTOL aircraft

NASA Technical Reports Server (NTRS)

Hoffman, W. C.; Kleinman, D. L.; Young, L. R.

1976-01-01

A systematic design methodology for pilot displays in advanced commercial VTOL aircraft was developed and refined. The analyst is provided with a step-by-step procedure for conducting conceptual display/control configurations evaluations for simultaneous monitoring and control pilot tasks. The approach consists of three phases: formulation of information requirements, configuration evaluation, and system selection. Both the monitoring and control performance models are based upon the optimal control model of the human operator. Extensions to the conventional optimal control model required in the display design methodology include explicit optimization of control/monitoring attention; simultaneous monitoring and control performance predictions; and indifference threshold effects. The methodology was applied to NASA's experimental CH-47 helicopter in support of the VALT program. The CH-47 application examined the system performance of six flight conditions. Four candidate configurations are suggested for evaluation in pilot-in-the-loop simulations and eventual flight tests.

Plant Photosynthesis-Irradiance Curve Responses to Pollution Show Non-Competitive Inhibited Michaelis Kinetics

PubMed Central

Lin, Maozi; Wang, Zhiwei; He, Lingchao; Xu, Kang; Cheng, Dongliang; Wang, Genxuan

2015-01-01

Photosynthesis-irradiance (PI) curves are extensively used in field and laboratory research to evaluate the photon-use efficiency of plants. However, most existing models for PI curves focus on the relationship between the photosynthetic rate (Pn) and photosynthetically active radiation (PAR), and do not take account of the influence of environmental factors on the curve. In the present study, we used a new non-competitive inhibited Michaelis-Menten model (NIMM) to predict the co-variation of Pn, PAR, and the relative pollution index (I). We then evaluated the model with published data and our own experimental data. The results indicate that the Pn of plants decreased with increasing I in the environment and, as predicted, were all fitted well by the NIMM model. Therefore, our model provides a robust basis to evaluate and understand the influence of environmental pollution on plant photosynthesis. PMID:26561863

Modal analysis of the human neck in vivo as a criterion for crash test dummy evaluation

NASA Astrophysics Data System (ADS)

Willinger, R.; Bourdet, N.; Fischer, R.; Le Gall, F.

2005-10-01

Low speed rear impact remains an acute automative safety problem because of a lack of knowledge of the mechanical behaviour of the human neck early after impact. Poorly validated mathematical models of the human neck or crash test dummy necks make it difficult to optimize automotive seats and head rests. In this study we have constructed an experimental and theoretical modal analysis of the human head-neck system in the sagittal plane. The method has allowed us to identify the mechanical properties of the neck and to validate a mathematical model in the frequency domain. The extracted modal characteristics consist of a first natural frequency at 1.3±0.1 Hz associated with head flexion-extension motion and a second mode at 8±0.7 Hz associated with antero-posterior translation of the head, also called retraction motion. Based on this new validation parameters we have been able to compare the human and crash test dummy frequency response functions and to evaluate their biofidelity. Three head-neck systems of current test dummies dedicated for use in rear-end car crash accident investigations have been evaluated in the frequency domain. We did not consider any to be acceptable, either because of excessive rigidity of their flexion-extension mode or because they poorly reproduce the head translation mode. In addition to dummy evaluation, this study provides new insight into injury mechanisms when a given natural frequency can be linked to a specific neck deformation.

Extension of an assessment model of ship traffic exhaust emissions for particulate matter and carbon monoxide

NASA Astrophysics Data System (ADS)

Jalkanen, J.-P.; Johansson, L.; Kukkonen, J.; Brink, A.; Kalli, J.; Stipa, T.

2012-03-01

A method is presented for the evaluation of the exhaust emissions of marine traffic, based on the messages provided by the Automatic Identification System (AIS), which enable the positioning of ship emissions with a high spatial resolution (typically a few tens of metres). The model also takes into account the detailed technical data of each individual vessel. The previously developed model was applicable for evaluating the emissions of NOx, SOx and CO2. This paper addresses a substantial extension of the modelling system, to allow also for the mass-based emissions of particulate matter (PM) and carbon monoxide (CO). The presented Ship Traffic Emissions Assessment Model (STEAM2) allows for the influences of accurate travel routes and ship speed, engine load, fuel sulphur content, multiengine setups, abatement methods and waves. We address in particular the modeling of the influence on the emissions of both engine load and the sulphur content of the fuel. The presented methodology can be used to evaluate the total PM emissions, and those of organic carbon, elemental carbon, ash and hydrated sulphate. We have evaluated the performance of the extended model against available experimental data on engine power, fuel consumption and the composition-resolved emissions of PM. We have also compared the annually averaged emission values with those of the corresponding EMEP inventory, As example results, the geographical distributions of the emissions of PM and CO are presented for the marine regions of the Baltic Sea surrounding the Danish Straits.

The applied importance of research on the matching law

PubMed Central

Pierce, W. David; Epling, W. Frank

1995-01-01

In this essay, we evaluate the applied implications of two articles related to the matching law and published in the Journal of the Experimental Analysis of Behavior, May 1994. Building on Mace's (1994) criteria for increasing the applied relevance of basic research, we evaluate the applied implications of basic research studies. Research by Elsmore and McBride (1994) and Savastano and Fantino (1994) involve an extension of the behavioral model of choice. Elsmore and McBride used rats as subjects, but arranged a multioperant environment that resembles some of the complex contingencies of human behavior. Savastino and Fantino used human subjects and extended the matching law to ratio and interval contingencies. These experiments contribute to a growing body of knowledge on the matching law and its relevance for human behavior. PMID:16795866

Utilizing Evaluation To Develop a Marketing Strategy in the Louisiana Cooperative Extension Service.

ERIC Educational Resources Information Center

Coreil, Paul D.; Verma, Satish

Marketing has become a popular strategic initiative among state extension services to meet the growing demand for program accountability. The Louisiana Cooperative Extension Service (LCES) began a formative evaluation of its marketing efforts as a step toward a comprehensive marketing plan. All extension faculty were surveyed to determine their…

NREL Opens Large Database of Inorganic Thin-Film Materials | News | NREL

Science.gov Websites

Inorganic Thin-Film Materials April 3, 2018 An extensive experimental database of inorganic thin-film Energy Laboratory (NREL) is now publicly available. The High Throughput Experimental Materials (HTEM Schroeder / NREL) "All existing experimental databases either contain many entries or have all this

Experimental evaluation of the extended Dytlewski-style dead time correction formalism for neutron multiplicity counting

DOE PAGES

Lockhart, M.; Henzlova, D.; Croft, S.; ...

2017-09-20

Over the past few decades, neutron multiplicity counting has played an integral role in Special Nuclear Material (SNM) characterization pertaining to nuclear safeguards. Current neutron multiplicity analysis techniques use singles, doubles, and triples count rates because a methodology to extract and dead time correct higher order count rates (i.e. quads and pents) was not fully developed. This limitation is overcome by the recent extension of a popular dead time correction method developed by Dytlewski. This extended dead time correction algorithm, named Dytlewski-Croft-Favalli (DCF), is detailed in reference Croft and Favalli (2017), which gives an extensive explanation of the theory andmore » implications of this new development. Dead time corrected results can then be used to assay SNM by inverting a set of extended point model equations which as well have only recently been formulated. Here, we discuss and present the experimental evaluation of practical feasibility of the DCF dead time correction algorithm to demonstrate its performance and applicability in nuclear safeguards applications. In order to test the validity and effectiveness of the dead time correction for quads and pents, 252Cf and SNM sources were measured in high efficiency neutron multiplicity counters at the Los Alamos National Laboratory (LANL) and the count rates were extracted up to the fifth order and corrected for dead time. To assess the DCF dead time correction, the corrected data is compared to traditional dead time correction treatment within INCC. In conclusion, the DCF dead time correction is found to provide adequate dead time treatment for broad range of count rates available in practical applications.« less

Experimental evaluation of the extended Dytlewski-style dead time correction formalism for neutron multiplicity counting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lockhart, M.; Henzlova, D.; Croft, S.

Over the past few decades, neutron multiplicity counting has played an integral role in Special Nuclear Material (SNM) characterization pertaining to nuclear safeguards. Current neutron multiplicity analysis techniques use singles, doubles, and triples count rates because a methodology to extract and dead time correct higher order count rates (i.e. quads and pents) was not fully developed. This limitation is overcome by the recent extension of a popular dead time correction method developed by Dytlewski. This extended dead time correction algorithm, named Dytlewski-Croft-Favalli (DCF), is detailed in reference Croft and Favalli (2017), which gives an extensive explanation of the theory andmore » implications of this new development. Dead time corrected results can then be used to assay SNM by inverting a set of extended point model equations which as well have only recently been formulated. Here, we discuss and present the experimental evaluation of practical feasibility of the DCF dead time correction algorithm to demonstrate its performance and applicability in nuclear safeguards applications. In order to test the validity and effectiveness of the dead time correction for quads and pents, 252Cf and SNM sources were measured in high efficiency neutron multiplicity counters at the Los Alamos National Laboratory (LANL) and the count rates were extracted up to the fifth order and corrected for dead time. To assess the DCF dead time correction, the corrected data is compared to traditional dead time correction treatment within INCC. In conclusion, the DCF dead time correction is found to provide adequate dead time treatment for broad range of count rates available in practical applications.« less

[sgRNA design for the CRISPR/Cas9 system and evaluation of its off-target effects].

PubMed

Xie, Sheng-song; Zhang, Yi; Zhang, Li-sheng; Li, Guang-lei; Zhao, Chang-zhi; Ni, Pan; Zhao, Shu-hong

2015-11-01

The third generation of CRISPR/Cas9-mediated genome editing technology has been successfully applied to genome modification of various species including animals, plants and microorganisms. How to improve the efficiency of CRISPR/Cas9 genome editing and reduce its off-target effects has been extensively explored in this field. Using sgRNA (Small guide RNA) with high efficiency and specificity is one of the critical factors for successful genome editing. Several software have been developed for sgRNA design and/or off-target evaluation, which have advantages and disadvantages respectively. In this review, we summarize characters of 16 kinds online and standalone software for sgRNA design and/or off-target evaluation and conduct a comparative analysis of these different kinds of software through developing 38 evaluation indexes. We also summarize 11 experimental approaches for testing genome editing efficiency and off-target effects as well as how to screen highly efficient and specific sgRNA.

Non-linear effects in finite amplitude wave propagation through ducts and nozzles

NASA Technical Reports Server (NTRS)

Salikuddin, M.; Brown, W. H.

1986-01-01

In this paper an extensive study of non-linear effects in finite amplitude wave propagation through ducts and nozzles is summarized. Some results from earlier studies are included to illustrate the non-linear effects on the transmission characteristics of duct and nozzle terminations. Investigaiations, both experimental and analytical, were carried out to determine the magnitudes of the effects for high intensity pulse propagation. The results derived from these investigations are presented in this paper. They include the effect of the sound intensity on the acoustic characteristics of duct and nozzle terminations, the extent of the non-linearities in the propagation of high intensity impulsive sound inside the duct and out into free field, the acoustic energy dissipation mechanism at a termination as shown by flow visualizations, and quantitative evaluations by experimental and analytical means of the influence of the intensity of a sound pulse on the dissipation of its acoustic power.

Analytical Derivation and Experimental Evaluation of Short-Bearing Approximation for Full Journal Bearing

NASA Technical Reports Server (NTRS)

Dubois, George B; Ocvirk, Fred W

1953-01-01

An approximate analytical solution including the effect of end leakage from the oil film of short plain bearings is presented because of the importance of endwise flow in sleeve bearings of the short lengths commonly used. The analytical approximation is supported by experimental data, resulting in charts which facilitate analysis of short plain bearings. The analytical approximation includes the endwise flow and that part of the circumferential flow which is related to surface velocity and film thickness but neglects the effect of film pressure on the circumferential flow. In practical use, this approximation applies best to bearings having a length-diameter ratio up to 1, and the effects of elastic deflection, inlet oil pressure, and changes of clearance with temperature minimize the relative importance of the neglected term. The analytical approximation was found to be an extension of a little-known pressure-distribution function originally proposed by Michell and Cardullo.

Road Nail: Experimental Solar Powered Intelligent Road Marking System

NASA Astrophysics Data System (ADS)

Samardžija, Dragan; Teslić, Nikola; Todorović, Branislav M.; Kovač, Erne; Isailović, Đorđe; Miladinović, Bojan

2012-03-01

Driving in low visibility conditions (night time, fog or heavy precipitation) is particularly challenging task with an increased probability of traffic accidents and possible injuries. Road Nail is a solar powered intelligent road marking system of wirelessly networked signaling devices that improve driver safety in low visibility conditions along hazardous roadways. Nails or signaling devices are autonomous nodes with capability to accumulate energy, exchange wireless messages, detect approaching vehicles and emit signalization light. We have built an experimental test-bed that consists of 20 nodes and a cellular gateway. Implementation details of the above system, including extensive measurements and performance evaluations in realistic field deployments are presented. A novel distributed network topology discovery scheme is proposed which integrates both sensor and wireless communication aspects, where nodes act autonomously. Finally, integration of the Road Nail system with the cellular network and the Internet is described.

Topiramate as a neuroprotective agent in a rat model of spinal cord injury.

PubMed

Narin, Firat; Hanalioglu, Sahin; Ustun, Huseyin; Kilinc, Kamer; Bilginer, Burcak

2017-12-01

Topiramate (TPM) is a widely used antiepileptic and antimigraine agent which has been shown to exert neuroprotective effects in various experimental traumatic brain injury and stroke models. However, its utility in spinal cord injury has not been studied extensively. Thus, we evaluated effects of TPM on secondary cellular injury mechanisms in an experimental rat model of traumatic spinal cord injury (SCI). After rat models of thoracic contusive SCI were established by free weight-drop method, TPM (40 mg/kg) was given at 12-hour intervals for four times orally. Post TPM treatment, malondialdehyde and protein carbonyl levels were significantly reduced and reduced glutathione levels were increased, while immunoreactivity for endothelial nitric oxide synthase, inducible nitric oxide synthase, and apoptotic peptidase activating factor 1 was diminished in SCI rats. In addition, TPM treatment improved the functional recovery of SCI rats. This study suggests that administration of TPM exerts neuroprotective effects on SCI.

Evaluation of Faculty Performance in Extension and Service. AIR 1989 Annual Forum Paper.

ERIC Educational Resources Information Center

Montgomery, James R.; And Others

A widespread perception exists that faculty with public service or extension activities are not treated equitably either in annual evaluations for merit salary increases or in peer evaluation for promotion. To determine the items considered important in making personnel decisions in extension and service areas, a survey was sent to chief academic…

The Role of Evaluation in Determining the Public Value of Extension

ERIC Educational Resources Information Center

Franz, Nancy; Arnold, Mary; Baughman, Sarah

2014-01-01

Extension has developed a strong evaluation culture across the system for the last 15 years. Yet measures are still limited to the private value of programs, looking at problems in a linear way and at isolated efforts. Across the country, Extension evaluators and administrators need to step up to help answer the "so what?" question about…

Gastroprotective effects of Corchorus olitorius leaf extract against ethanol-induced gastric mucosal hemorrhagic lesions in rats.

PubMed

Al Batran, Rami; Al-Bayaty, Fouad; Abdulla, Mahmood Ameen; Al-Obaidi, Mazen M Jamil; Hajrezaei, Maryam; Hassandarvish, Pouya; Fouad, Mustafa; Golbabapour, Shahram; Talaee, Samaneh

2013-08-01

Corchorus olitorius is a medicinal plant traditionally utilized as an antifertility, anti-convulsive, and purgative agent. This study aimed to evaluate the gastroprotective effect of an ethanolic extract of C. olitorius against ethanol-induced gastric ulcers in adult Sprague Dawley rats. The rats were divided into seven groups according to their pretreatment: an untreated control group, an ulcer control group, a reference control group (20 mg/kg omeprazole), and four experimental groups (50, 100, 200, or 400 mg/kg of extract). Carboxymethyl cellulose was the vehicle for the agents. Prior to the induction of gastric ulcers with absolute ethanol, the rats in each group were pretreated orally. An hour later, the rats were sacrificed, and gastric tissues were collected to evaluate the ulcers and to measure enzymatic activity. The tissues were subjected to histological and immunohistochemical evaluations. Compared with the extensive mucosal damage in the ulcer control group, gross evaluation revealed a marked protection of the gastric mucosa in the experimental groups, with significantly preserved gastric wall mucus. In these groups, superoxide dismutase and malondialdehyde levels were significantly increased (P < 0.05) and reduced (P < 0.05), respectively. In addition to the histologic analyses (HE and periodic acid-Schiff staining), immunohistochemistry confirmed the protection through the upregulation of Hsp70 and the downregulation of Bax proteins. The gastroprotection of the experimental groups was comparable to that of the reference control medicine omeprazole. Our study reports the gastroprotective property of an ethanolic extract of C. olitorius against ethanol-induced gastric mucosal hemorrhagic lesions in rats. © 2013 The Authors. Journal of Gastroenterology and Hepatology published by Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

Gastroprotective effects of Corchorus olitorius leaf extract against ethanol-induced gastric mucosal hemorrhagic lesions in rats

PubMed Central

Al Batran, Rami; Al-Bayaty, Fouad; Ameen Abdulla, Mahmood; Jamil Al-Obaidi, Mazen M; Hajrezaei, Maryam; Hassandarvish, Pouya; Fouad, Mustafa; Golbabapour, Shahram; Talaee, Samaneh

2013-01-01

Background and AimCorchorus olitorius is a medicinal plant traditionally utilized as an antifertility, anti-convulsive, and purgative agent. This study aimed to evaluate the gastroprotective effect of an ethanolic extract of C. olitorius against ethanol-induced gastric ulcers in adult Sprague Dawley rats. MethodsThe rats were divided into seven groups according to their pretreatment: an untreated control group, an ulcer control group, a reference control group (20 mg/kg omeprazole), and four experimental groups (50, 100, 200, or 400 mg/kg of extract). Carboxymethyl cellulose was the vehicle for the agents. Prior to the induction of gastric ulcers with absolute ethanol, the rats in each group were pretreated orally. An hour later, the rats were sacrificed, and gastric tissues were collected to evaluate the ulcers and to measure enzymatic activity. The tissues were subjected to histological and immunohistochemical evaluations. ResultsCompared with the extensive mucosal damage in the ulcer control group, gross evaluation revealed a marked protection of the gastric mucosa in the experimental groups, with significantly preserved gastric wall mucus. In these groups, superoxide dismutase and malondialdehyde levels were significantly increased (P < 0.05) and reduced (P < 0.05), respectively. In addition to the histologic analyses (HE and periodic acid-Schiff staining), immunohistochemistry confirmed the protection through the upregulation of Hsp70 and the downregulation of Bax proteins. The gastroprotection of the experimental groups was comparable to that of the reference control medicine omeprazole. ConclusionsOur study reports the gastroprotective property of an ethanolic extract of C. olitorius against ethanol-induced gastric mucosal hemorrhagic lesions in rats. PMID:23611708

X-ray natural widths, level widths and Coster-Kronig transition probabilities

NASA Astrophysics Data System (ADS)

Papp, T.; Campbell, J. L.; Varga, D.

1997-01-01

A critical review is given for the K-N7 atomic level widths. The experimental level widths were collected from x-ray photoelectron spectroscopy (XPS), x-ray emission spectroscopy (XES), x-ray spectra fluoresced by synchrotron radiation, and photoelectrons from x-ray absorption (PAX). There are only limited atomic number ranges for a few atomic levels where data are available from more than one source. Generally the experimental level widths have large scatter compared to the reported error bars. The experimental data are compared with the recent tabulation of Perkins et al. and of Ohno et al. Ohno et al. performed a many body approach calculation for limited atomic number ranges and have obtained reasonable agreement with the experimental data. Perkins et al. presented a tabulation covering the K-Q1 shells of all atoms, based on extensions of the Scofield calculations for radiative rates and extensions of the Chen calculations for non-radiative rates. The experimental data are in disagreement with this tabulation, in excess of a factor of two in some cases. A short introduction to the experimental Coster-Kronig transition probabilities is presented. It is our opinion that the different experimental approaches result in systematically different experimental data.

simulation of the DNA force-extension curve

NASA Astrophysics Data System (ADS)

Shinaberry, Gregory; Mikhaylov, Ivan; Balaeff, Alexander

A molecular dynamics simulation study of the force-extension curve of double-stranded DNA is presented. Extended simulations of the DNA at multiple points along the force-extension curve are conducted with DNA end-to-end length constrained at each point. The calculated force-extension curve qualitatively reproduces the experimental one. The DNA conformational ensemble at each extension shows that the famous plateau of the force-extension curve results from B-DNA melting, whereas the formation of the earlier-predicted novel DNA conformation called 'zip-DNA' takes place at extensions past the plateau. An extensive analysis of the DNA conformational ensemble in terms of base configuration, backbone configuration, solvent interaction energy, etc., is conducted in order to elucidate the physical origin of DNA elasticity and the main interactions responsible for the shape of the force-extension curve.

Photogrammetric registration of dental plaque accumulation in vivo.

PubMed

Bergström, J

1981-01-01

Using the labial surface of upper anterior laterals for determination, the accumulation of plaque was assessed by means of a stereo-photogrammetric method. The stereoimages were subjected to photogrammetric evaluation, the part of the surface area covered by plaque being given in per cent of the total surface area of the tooth. Plaque extension and plaque topography was studied in young adults with healthy periodontia during a 20 day period of no oral hygiene. At the end of the experimental period, on an average 75 per cent of the surface area was covered by plaque, corresponding to an extension rate of 3.75 per cent per day. The correlation between plaque values obtained by photogrammetry and various estimates obtained from clinical scoring ranged between r = 0.66 and r = 0.78. It is concluded that the method introduced is a sensitive means of determining small amounts of plaque and should prove useful for in vivo investigation of plaque growth and plaque suppression, where measurements of high quality is of importance.

Real-Time Robust Tracking for Motion Blur and Fast Motion via Correlation Filters.

PubMed

Xu, Lingyun; Luo, Haibo; Hui, Bin; Chang, Zheng

2016-09-07

Visual tracking has extensive applications in intelligent monitoring and guidance systems. Among state-of-the-art tracking algorithms, Correlation Filter methods perform favorably in robustness, accuracy and speed. However, it also has shortcomings when dealing with pervasive target scale variation, motion blur and fast motion. In this paper we proposed a new real-time robust scheme based on Kernelized Correlation Filter (KCF) to significantly improve performance on motion blur and fast motion. By fusing KCF and STC trackers, our algorithm also solve the estimation of scale variation in many scenarios. We theoretically analyze the problem for CFs towards motions and utilize the point sharpness function of the target patch to evaluate the motion state of target. Then we set up an efficient scheme to handle the motion and scale variation without much time consuming. Our algorithm preserves the properties of KCF besides the ability to handle special scenarios. In the end extensive experimental results on benchmark of VOT datasets show our algorithm performs advantageously competed with the top-rank trackers.

Towards Resilient Critical Infrastructures: Application of Type-2 Fuzzy Logic in Embedded Network Security Cyber Sensor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ondrej Linda; Todd Vollmer; Jim Alves-Foss

2011-08-01

Resiliency and cyber security of modern critical infrastructures is becoming increasingly important with the growing number of threats in the cyber-environment. This paper proposes an extension to a previously developed fuzzy logic based anomaly detection network security cyber sensor via incorporating Type-2 Fuzzy Logic (T2 FL). In general, fuzzy logic provides a framework for system modeling in linguistic form capable of coping with imprecise and vague meanings of words. T2 FL is an extension of Type-1 FL which proved to be successful in modeling and minimizing the effects of various kinds of dynamic uncertainties. In this paper, T2 FL providesmore » a basis for robust anomaly detection and cyber security state awareness. In addition, the proposed algorithm was specifically developed to comply with the constrained computational requirements of low-cost embedded network security cyber sensors. The performance of the system was evaluated on a set of network data recorded from an experimental cyber-security test-bed.« less

Extension of nanoconfined DNA: Quantitative comparison between experiment and theory

NASA Astrophysics Data System (ADS)

Iarko, V.; Werner, E.; Nyberg, L. K.; Müller, V.; Fritzsche, J.; Ambjörnsson, T.; Beech, J. P.; Tegenfeldt, J. O.; Mehlig, K.; Westerlund, F.; Mehlig, B.

2015-12-01

The extension of DNA confined to nanochannels has been studied intensively and in detail. However, quantitative comparisons between experiments and model calculations are difficult because most theoretical predictions involve undetermined prefactors, and because the model parameters (contour length, Kuhn length, effective width) are difficult to compute reliably, leading to substantial uncertainties. Here we use a recent asymptotically exact theory for the DNA extension in the "extended de Gennes regime" that allows us to compare experimental results with theory. For this purpose, we performed experiments measuring the mean DNA extension and its standard deviation while varying the channel geometry, dye intercalation ratio, and ionic strength of the buffer. The experimental results agree very well with theory at high ionic strengths, indicating that the model parameters are reliable. At low ionic strengths, the agreement is less good. We discuss possible reasons. In principle, our approach allows us to measure the Kuhn length and the effective width of a single DNA molecule and more generally of semiflexible polymers in solution.

Validation of Cross Sections for Monte Carlo Simulation of the Photoelectric Effect

NASA Astrophysics Data System (ADS)

Han, Min Cheol; Kim, Han Sung; Pia, Maria Grazia; Basaglia, Tullio; Batič, Matej; Hoff, Gabriela; Kim, Chan Hyeong; Saracco, Paolo

2016-04-01

Several total and partial photoionization cross section calculations, based on both theoretical and empirical approaches, are quantitatively evaluated with statistical analyses using a large collection of experimental data retrieved from the literature to identify the state of the art for modeling the photoelectric effect in Monte Carlo particle transport. Some of the examined cross section models are available in general purpose Monte Carlo systems, while others have been implemented and subjected to validation tests for the first time to estimate whether they could improve the accuracy of particle transport codes. The validation process identifies Scofield's 1973 non-relativistic calculations, tabulated in the Evaluated Photon Data Library (EPDL), as the one best reproducing experimental measurements of total cross sections. Specialized total cross section models, some of which derive from more recent calculations, do not provide significant improvements. Scofield's non-relativistic calculations are not surpassed regarding the compatibility with experiment of K and L shell photoionization cross sections either, although in a few test cases Ebel's parameterization produces more accurate results close to absorption edges. Modifications to Biggs and Lighthill's parameterization implemented in Geant4 significantly reduce the accuracy of total cross sections at low energies with respect to its original formulation. The scarcity of suitable experimental data hinders a similar extensive analysis for the simulation of the photoelectron angular distribution, which is limited to a qualitative appraisal.

Experimental Demonstration of Frequency Regulation by Commercial Buildings – Part II: Results and Performance Evaluation

DOE PAGES

Vrettos, Evangelos; Kara, Emre Can; MacDonald, Jason; ...

2016-11-15

This paper is the second part of a two-part series presenting the results from an experimental demonstration of frequency regulation in a commercial building test facility. We developed relevant building models and designed a hierarchical controller for reserve scheduling, building climate control and frequency regulation in Part I. In Part II, we introduce the communication architecture and experiment settings, and present extensive experimental results under frequency regulation. More specifically, we compute the day-ahead reserve capacity of the test facility under different assumptions and conditions. Furthermore, we demonstrate the ability of model predictive control to satisfy comfort constraints under frequency regulation,more » and show that fan speed control can track the fast-moving RegD signal of the Pennsylvania, Jersey, and Maryland Power Market (PJM) very accurately. In addition, we discuss potential effects of frequency regulation on building operation (e.g., increase in energy consumption, oscillations in supply air temperature, and effect on chiller cycling), and provide suggestions for real-world implementation projects. Our results show that hierarchical control is appropriate for frequency regulation from commercial buildings.« less

Toxicology of chemical mixtures: Experimental approaches, underlying concepts, and some results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, R.S.; Long, H.L.; Boorman, G.A.

1990-07-01

The toxicology of chemical mixtures will be the toxicology of the 1990s and beyond. While this branch of toxicology most closely reflects the actual human exposure situation, as yet there is no standard protocol or consensus methodology for investigating the toxicology of mixtures. Thus, in this emerging science, experimentation is required just to develop a broadly applicable evaluation system. Several examples are discussed to illustrate the different experimental designs and the concepts behind each. These include the health effects studies of Love Canal soil samples, the Lake Ontario Coho salmon, the water samples repurified from secondary sewage in the citymore » of Denver Potable Water Reuse Demonstration Plant, and the National Toxicology Program (NTP) effort on a mixture of 25 frequently detected groundwater contaminants derived from hazardous waste disposal sites. In the last instance, an extensive research program has been ongoing for the last two years at the NTP, encompassing general toxicology, immunotoxicology, developmental and reproductive toxicology, biochemical toxicology, myelotoxicology, genetic toxicology, neurobehavioral toxicology, and hepato- and renal toxicology.« less

Blade Surface Pressure Distributions in a Rocket Engine Turbine: Experimental Work With On-Blade Pressure Transducers

NASA Technical Reports Server (NTRS)

Hudson, Susan T.; Zoladz, Thomas F.; Griffin, Lisa W.; Turner, James E. (Technical Monitor)

2000-01-01

Understanding the unsteady aspects of turbine rotor flowfields is critical to successful future turbine designs. A technology program was conducted at NASA's Marshall Space Flight Center to increase the understanding of unsteady environments for rocket engine turbines. The experimental program involved instrumenting turbine rotor blades with surface-mounted high frequency response pressure transducers. The turbine model was then tested to measure the unsteady pressures on the rotor blades. The data obtained from the experimental program is unique in three respects. First, much more unsteady data was obtained (several minutes per set point) than has been possible in the past. Also, two independent unsteady data acquisition systems and fundamental signal processing approaches were used. Finally, an extensive steady performance database existed for the turbine model. This allowed an evaluation of the effect of the on-blade instrumentation on the turbine's performance. This unique data set, the lessons learned for acquiring this type of data, and the improvements made to the data analysis and prediction tools will contribute to future turbine programs such as those for reusable launch vehicles.

75 FR 71699 - Pesticide Experimental Use Permits; Receipt of Amendment and Extension Applications; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-24

... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2010-0926; FRL-8853-7] Pesticide Experimental Use... and 264-EUP-143 from Bayer CropScience LP requesting to amend and extend the existing experimental use... fair treatment and meaningful involvement of any group, including minority and/or low income...

Applications of the Integrated High-Performance CMOS Image Sensor to Range Finders — from Optical Triangulation to the Automotive Field

PubMed Central

Wu, Jih-Huah; Pen, Cheng-Chung; Jiang, Joe-Air

2008-01-01

With their significant features, the applications of complementary metal-oxide semiconductor (CMOS) image sensors covers a very extensive range, from industrial automation to traffic applications such as aiming systems, blind guidance, active/passive range finders, etc. In this paper CMOS image sensor-based active and passive range finders are presented. The measurement scheme of the proposed active/passive range finders is based on a simple triangulation method. The designed range finders chiefly consist of a CMOS image sensor and some light sources such as lasers or LEDs. The implementation cost of our range finders is quite low. Image processing software to adjust the exposure time (ET) of the CMOS image sensor to enhance the performance of triangulation-based range finders was also developed. An extensive series of experiments were conducted to evaluate the performance of the designed range finders. From the experimental results, the distance measurement resolutions achieved by the active range finder and the passive range finder can be better than 0.6% and 0.25% within the measurement ranges of 1 to 8 m and 5 to 45 m, respectively. Feasibility tests on applications of the developed CMOS image sensor-based range finders to the automotive field were also conducted. The experimental results demonstrated that our range finders are well-suited for distance measurements in this field. PMID:27879789

Comparative analysis of international standards for the fatigue testing of posterior spinal fixation systems: the importance of preload in ISO 12189.

PubMed

La Barbera, Luigi; Ottardi, Claudia; Villa, Tomaso

2015-10-01

Preclinical evaluation of the mechanical reliability of fixation devices is a mandatory activity before their introduction into market. There are two standardized protocols for preclinical testing of spinal implants. The American Society for Testing Materials (ASTM) recommends the F1717 standard, which describes a vertebrectomy condition that is relatively simple to implement, whereas the International Organization for Standardization (ISO) suggests the 12189 standard, which describes a more complex physiological anterior support-based setup. Moreover, ASTM F1717 is nowadays well established, whereas ISO 12189 has received little attention: A few studies tried to accurately describe the ISO experimental procedure through numeric models, but these studies totally neglect the recommended precompression step. This study aimed to build up a reliable, validated numeric model capable of describing the stress on the rods of a spinal fixator assembled according to ISO 12189 standard procedure. Such a model would more adequately represent the in vitro testing condition. This study used finite element (FE) simulations and experimental validation testing. An FE model of the ISO setup was built to calculate the stress on the rods. Simulation was validated by comparison with experimental strain gauges measurements. The same fixator has been previously virtually mounted in an L2-L4 FE model of the lumbar spine, and stresses in the rods were calculated when the spine was subjected to physiological forces and moments. The comparison between the FE predictions and experimental measurements is in good agreement, thus confirming the suitability of the FE method to evaluate the stresses in the device. The initial precompression induces a significant extension of the assembled construct. As the applied load increases, the initial extension is gradually compensated, so that at peak load the rods are bent in flexion: The final stress value predicted is thus reduced to about 50%, if compared with the previous model where the precompression was not considered. Neglecting the initial preload due to the assembly of the overall construct according to ISO 12189 standard could lead to an overestimation of the stress on the rods up to 50%. To correctly describe the state of stress on the posterior spinal fixator, tested according to the ISO procedure, it is important to take into account the initial preload due to the assembly of the overall construct. Copyright © 2015 Elsevier Inc. All rights reserved.

Performance evaluation of extension education centers in universities based on the balanced scorecard.

PubMed

Wu, Hung-Yi; Lin, Yi-Kuei; Chang, Chi-Hsiang

2011-02-01

This study aims at developing a set of appropriate performance evaluation indices mainly based on balanced scorecard (BSC) for extension education centers in universities by utilizing multiple criteria decision making (MCDM). Through literature reviews and experts who have real practical experiences in extension education, adequate performance evaluation indices have been selected and then utilizing the decision making trial and evaluation laboratory (DEMATEL) and analytic network process (ANP), respectively, further establishes the causality between the four BSC perspectives as well as the relative weights between evaluation indices. According to this previous result, an empirical analysis of the performance evaluation of extension education centers of three universities at Taoyuan County in Taiwan is illustrated by applying VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR). From the analysis results, it indicates that "Learning and growth" is the significant influential factor and it would affect the other three perspectives. In addition, it is discovered that "Internal process" perspective as well as "Financial" perspective play important roles in the performance evaluation of extension education centers. The top three key performance indices are "After-sales service", "Turnover volume", and "Net income". The proposed evaluation model could be considered as a reference for extension education centers in universities to prioritize their improvements on the key performance indices after performing VIKOR analyses. 2010 Elsevier Ltd. All rights reserved.

Experimental validation of a new heterogeneous mechanical test design

NASA Astrophysics Data System (ADS)

Aquino, J.; Campos, A. Andrade; Souto, N.; Thuillier, S.

2018-05-01

Standard material parameters identification strategies generally use an extensive number of classical tests for collecting the required experimental data. However, a great effort has been made recently by the scientific and industrial communities to support this experimental database on heterogeneous tests. These tests can provide richer information on the material behavior allowing the identification of a more complete set of material parameters. This is a result of the recent development of full-field measurements techniques, like digital image correlation (DIC), that can capture the heterogeneous deformation fields on the specimen surface during the test. Recently, new specimen geometries were designed to enhance the richness of the strain field and capture supplementary strain states. The butterfly specimen is an example of these new geometries, designed through a numerical optimization procedure where an indicator capable of evaluating the heterogeneity and the richness of strain information. However, no experimental validation was yet performed. The aim of this work is to experimentally validate the heterogeneous butterfly mechanical test in the parameter identification framework. For this aim, DIC technique and a Finite Element Model Up-date inverse strategy are used together for the parameter identification of a DC04 steel, as well as the calculation of the indicator. The experimental tests are carried out in a universal testing machine with the ARAMIS measuring system to provide the strain states on the specimen surface. The identification strategy is accomplished with the data obtained from the experimental tests and the results are compared to a reference numerical solution.

A hierarchical classification method for finger knuckle print recognition

NASA Astrophysics Data System (ADS)

Kong, Tao; Yang, Gongping; Yang, Lu

2014-12-01

Finger knuckle print has recently been seen as an effective biometric technique. In this paper, we propose a hierarchical classification method for finger knuckle print recognition, which is rooted in traditional score-level fusion methods. In the proposed method, we firstly take Gabor feature as the basic feature for finger knuckle print recognition and then a new decision rule is defined based on the predefined threshold. Finally, the minor feature speeded-up robust feature is conducted for these users, who cannot be recognized by the basic feature. Extensive experiments are performed to evaluate the proposed method, and experimental results show that it can achieve a promising performance.

Stochastic HKMDHE: A multi-objective contrast enhancement algorithm

NASA Astrophysics Data System (ADS)

Pratiher, Sawon; Mukhopadhyay, Sabyasachi; Maity, Srideep; Pradhan, Asima; Ghosh, Nirmalya; Panigrahi, Prasanta K.

2018-02-01

This contribution proposes a novel extension of the existing `Hyper Kurtosis based Modified Duo-Histogram Equalization' (HKMDHE) algorithm, for multi-objective contrast enhancement of biomedical images. A novel modified objective function has been formulated by joint optimization of the individual histogram equalization objectives. The optimal adequacy of the proposed methodology with respect to image quality metrics such as brightness preserving abilities, peak signal-to-noise ratio (PSNR), Structural Similarity Index (SSIM) and universal image quality metric has been experimentally validated. The performance analysis of the proposed Stochastic HKMDHE with existing histogram equalization methodologies like Global Histogram Equalization (GHE) and Contrast Limited Adaptive Histogram Equalization (CLAHE) has been given for comparative evaluation.

Backscattering of decametric waves on magnetically oriented ionosphere inhomogeneities

NASA Astrophysics Data System (ADS)

Sivokon', V. P.

2017-05-01

The method of study of magnetically oriented ionosphere inhomogeneities based on the analysis of radar decametric emission backscattering on inhomogeneities is proposed. It is shown that certain conditions, including the orientation of the propagation route relative to the Earth's magnetic field lines and the polarization and frequency of the emitted wave, make possible resonant backscattering of radiolocation system emission on magnetically oriented ionosphere inhomogeneities. The paper presents the results of experimental observation of scattering in Kamchatka Peninsula. They demonstrated the opportunity to evaluate the extension of the scattering region, the vertical and horizontal components of the velocities of magnetically oriented inhomogeneities, and the frequency dependence of these parameters.

Evaluation of an Integrated Curriculum in Physics, Mathematics, Engineering, and Chemistry

NASA Astrophysics Data System (ADS)

Beichner, Robert

1997-04-01

An experimental, student centered, introductory curriculum called IMPEC (for Integrated Mathematics, Physics, Engineering, and Chemistry curriculum) is in its third year of pilot-testing at NCSU. The curriculum is taught by a multidisciplinary team of professors using a combination of traditional lecturing and alternative instructional methods including cooperative learning, activity-based class sessions, and extensive use of computer modeling, simulations, and the world wide web. This talk will discuss the research basis for our design and implementation of the curriculum, the qualitative and quantitative methods we have been using to assess its effectiveness, and the educational outcomes we have noted so far.

Developing and evaluating a target-background similarity metric for camouflage detection.

PubMed

Lin, Chiuhsiang Joe; Chang, Chi-Chan; Liu, Bor-Shong

2014-01-01

Measurement of camouflage performance is of fundamental importance for military stealth applications. The goal of camouflage assessment algorithms is to automatically assess the effect of camouflage in agreement with human detection responses. In a previous study, we found that the Universal Image Quality Index (UIQI) correlated well with the psychophysical measures, and it could be a potentially camouflage assessment tool. In this study, we want to quantify the camouflage similarity index and psychophysical results. We compare several image quality indexes for computational evaluation of camouflage effectiveness, and present the results of an extensive human visual experiment conducted to evaluate the performance of several camouflage assessment algorithms and analyze the strengths and weaknesses of these algorithms. The experimental data demonstrates the effectiveness of the approach, and the correlation coefficient result of the UIQI was higher than those of other methods. This approach was highly correlated with the human target-searching results. It also showed that this method is an objective and effective camouflage performance evaluation method because it considers the human visual system and image structure, which makes it consistent with the subjective evaluation results.

Experimental evaluation of the Skylab orbital workshop ventilation system concept

NASA Technical Reports Server (NTRS)

Allums, S. L.; Hastings, L. J.; Ralston, J. T.

1972-01-01

Extensive testing was conducted to evaluate the Orbital Workshop ventilation concept. Component tests were utilized to determine the relationship between operating characteristics at 1 and 0.34 atm. System tests were conducted at 1 atm within the Orbital Workshop full-scale mockup to assess delivered volumetric flow rate and compartment air velocities. Component tests with the Anemostat circular diffusers (plenum- and duct-mounted) demonstrated that the diffuser produced essentially equivalent airflow patterns and velocities in 1- and 0.34-atm environments. The tests also showed that the pressure drop across the diffuser could be scaled from 1 to 0.34 atm using the atmosphere pressure ratio. Fan tests indicated that the performance of a multiple, parallel-mounted fan cluster could be predicted by summing the single-fan flow rates at a given delta P.

Thermal power systems small power systems applications project. Volume 2: Detailed report

NASA Technical Reports Server (NTRS)

Marriott, A. T.

1979-01-01

Small power system technology as applied to power plants up to 10 MW in size was considered. Markets for small power systems were characterized and cost goals were established for the project. Candidate power plant system design concepts were selected for evaluation and preliminary performance and cost assessments were made. Breakeven capital costs were determined for leading contenders among the candidate systems. The potential use of small power systems in providing part of the demand for pumping power by the extensive aqueduct system of California, was studied. Criteria and methodologies were developed for the ranking of candidate power plant system design concepts. Experimental power plant concepts of 1 MW rating were studied to define a power plant configuration for subsequent detail design construction, testing and evaluation. Site selection criteria and ground rules were developed.

NRMC - A GPU code for N-Reverse Monte Carlo modeling of fluids in confined media

NASA Astrophysics Data System (ADS)

Sánchez-Gil, Vicente; Noya, Eva G.; Lomba, Enrique

2017-08-01

NRMC is a parallel code for performing N-Reverse Monte Carlo modeling of fluids in confined media [V. Sánchez-Gil, E.G. Noya, E. Lomba, J. Chem. Phys. 140 (2014) 024504]. This method is an extension of the usual Reverse Monte Carlo method to obtain structural models of confined fluids compatible with experimental diffraction patterns, specifically designed to overcome the problem of slow diffusion that can appear under conditions of tight confinement. Most of the computational time in N-Reverse Monte Carlo modeling is spent in the evaluation of the structure factor for each trial configuration, a calculation that can be easily parallelized. Implementation of the structure factor evaluation in NVIDIA® CUDA so that the code can be run on GPUs leads to a speed up of up to two orders of magnitude.

Experimental segregation of iron-nickel metal, iron-sulfide, and olivine in a thermal gradient: Preliminary results

NASA Technical Reports Server (NTRS)

Jurewicz, Stephen R.; Jones, J. H.

1993-01-01

Speculation about the possible mechanisms for core formation in small asteroids raises more questions than answers. Petrologic evidence from iron meteorites, pallasites, and astronomical observations of M asteroids suggests that many small bodies were capable of core formation. Recent work by Taylor reviews the geochemical evidence and examines the possible physical/mechanical constraints on segregation processes. Taylor's evaluation suggests that extensive silicate partial melting (preferably 50 vol. percent or greater) is required before metal can segregate from the surrounding silicate and form a metal core. The arguments for large degrees of silicate partial melting are two-fold: (1) elemental trends in iron meteorites require that the metal was at is liquidus; and (2) experimental observations of metal/sulfide inclusions in partially molten silicate meteorites show that the metal/sulfide tends to form spherules in the liquid silicate due to surface tension effects. Taylor points out that for these metal spherules to sink through a silicate mush, high degrees of silicate partial melting are required to lower the silicate yield strength. Although some qualitative experimental data exists, little is actually known about the behavior of metals and liquid sulfides dispersed in silicate systems. In addition, we have been impressed with the ability of cumulative olivine to expel trapped liquid when placed in a thermal gradient. Consequently, we undertook to accomplish the following: (1) experimentally evaluate the potential for metal/sulfide/silicate segregation in a thermal gradient; and (2) obtain quantitative data of the wetting parameters of metal-sulfide melts among silicate grains.

Cadmium osteotoxicity in experimental animals: Mechanisms and relationship to human exposures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharyya, Maryka H.

Extensive epidemiological studies have recently demonstrated increased cadmium exposure correlating significantly with decreased bone mineral density and increased fracture incidence in humans at lower exposure levels than ever before evaluated. Studies in experimental animals have addressed whether very low concentrations of dietary cadmium can negatively impact the skeleton. This overview evaluates results in experimental animals regarding mechanisms of action on bone and the application of these results to humans. Results demonstrate that long-term dietary exposures in rats, at levels corresponding to environmental exposures in humans, result in increased skeletal fragility and decreased mineral density. Cadmium-induced demineralization begins soon after exposure,more » within 24 h of an oral dose to mice. In bone culture systems, cadmium at low concentrations acts directly on bone cells to cause both decreases in bone formation and increases in bone resorption, independent of its effects on kidney, intestine, or circulating hormone concentrations. Results from gene expression microarray and gene knock-out mouse models provide insight into mechanisms by which cadmium may affect bone. Application of the results to humans is considered with respect to cigarette smoke exposure pathways and direct vs. indirect effects of cadmium. Clearly, understanding the mechanism(s) by which cadmium causes bone loss in experimental animals will provide insight into its diverse effects in humans. Preventing bone loss is critical to maintaining an active, independent lifestyle, particularly among elderly persons. Identifying environmental factors such as cadmium that contribute to increased fractures in humans is an important undertaking and a first step to prevention.« less

14 CFR 1274.905 - Rights in data.

Code of Federal Regulations, 2013 CFR

2013-01-01

... research, experimental, developmental, engineering, demonstration, or design activities are to be carried... the agreement. If cost sharing is unequal or no extensive research, experimental, developmental, engineering, demonstration, or design activities are likely, a different set of provisions may be appropriate...

14 CFR 1274.905 - Rights in data.

Code of Federal Regulations, 2010 CFR

2010-01-01

... research, experimental, developmental, engineering, demonstration, or design activities are to be carried... the agreement. If cost sharing is unequal or no extensive research, experimental, developmental, engineering, demonstration, or design activities are likely, a different set of provisions may be appropriate...

UIUC concrete tie and fastener field testing at TTC.

DOT National Transportation Integrated Search

2014-07-01

In July 2012, the University of Illinois at Urbana-Champaign (UIUC) began an extensive : experimental program at the Transportation : Technology Center (TTC) in Pueblo, CO. The : field experimentation program was part of a : larger research program f...

Residual Upper Arm Motor Function Primes Innervation of Paretic Forearm Muscles in Chronic Stroke after Brain-Machine Interface (BMI) Training

PubMed Central

Curado, Marco Rocha; Cossio, Eliana Garcia; Broetz, Doris; Agostini, Manuel; Cho, Woosang; Brasil, Fabricio Lima; Yilmaz, Oezge; Liberati, Giulia; Lepski, Guilherme

2015-01-01

Background Abnormal upper arm-forearm muscle synergies after stroke are poorly understood. We investigated whether upper arm function primes paralyzed forearm muscles in chronic stroke patients after Brain-Machine Interface (BMI)-based rehabilitation. Shaping upper arm-forearm muscle synergies may support individualized motor rehabilitation strategies. Methods Thirty-two chronic stroke patients with no active finger extensions were randomly assigned to experimental or sham groups and underwent daily BMI training followed by physiotherapy during four weeks. BMI sessions included desynchronization of ipsilesional brain activity and a robotic orthosis to move the paretic limb (experimental group, n = 16). In the sham group (n = 16) orthosis movements were random. Motor function was evaluated with electromyography (EMG) of forearm extensors, and upper arm and hand Fugl-Meyer assessment (FMA) scores. Patients performed distinct upper arm (e.g., shoulder flexion) and hand movements (finger extensions). Forearm EMG activity significantly higher during upper arm movements as compared to finger extensions was considered facilitation of forearm EMG activity. Intraclass correlation coefficient (ICC) was used to test inter-session reliability of facilitation of forearm EMG activity. Results Facilitation of forearm EMG activity ICC ranges from 0.52 to 0.83, indicating fair to high reliability before intervention in both limbs. Facilitation of forearm muscles is higher in the paretic as compared to the healthy limb (p<0.001). Upper arm FMA scores predict facilitation of forearm muscles after intervention in both groups (significant correlations ranged from R = 0.752, p = 0.002 to R = 0.779, p = 0.001), but only in the experimental group upper arm FMA scores predict changes in facilitation of forearm muscles after intervention (R = 0.709, p = 0.002; R = 0.827, p<0.001). Conclusions Residual upper arm motor function primes recruitment of paralyzed forearm muscles in chronic stroke patients and predicts changes in their recruitment after BMI training. This study suggests that changes in upper arm-forearm synergies contribute to stroke motor recovery, and provides candidacy guidelines for similar BMI-based clinical practice. PMID:26495971

Residual Upper Arm Motor Function Primes Innervation of Paretic Forearm Muscles in Chronic Stroke after Brain-Machine Interface (BMI) Training.

PubMed

Curado, Marco Rocha; Cossio, Eliana Garcia; Broetz, Doris; Agostini, Manuel; Cho, Woosang; Brasil, Fabricio Lima; Yilmaz, Oezge; Liberati, Giulia; Lepski, Guilherme; Birbaumer, Niels; Ramos-Murguialday, Ander

2015-01-01

Abnormal upper arm-forearm muscle synergies after stroke are poorly understood. We investigated whether upper arm function primes paralyzed forearm muscles in chronic stroke patients after Brain-Machine Interface (BMI)-based rehabilitation. Shaping upper arm-forearm muscle synergies may support individualized motor rehabilitation strategies. Thirty-two chronic stroke patients with no active finger extensions were randomly assigned to experimental or sham groups and underwent daily BMI training followed by physiotherapy during four weeks. BMI sessions included desynchronization of ipsilesional brain activity and a robotic orthosis to move the paretic limb (experimental group, n = 16). In the sham group (n = 16) orthosis movements were random. Motor function was evaluated with electromyography (EMG) of forearm extensors, and upper arm and hand Fugl-Meyer assessment (FMA) scores. Patients performed distinct upper arm (e.g., shoulder flexion) and hand movements (finger extensions). Forearm EMG activity significantly higher during upper arm movements as compared to finger extensions was considered facilitation of forearm EMG activity. Intraclass correlation coefficient (ICC) was used to test inter-session reliability of facilitation of forearm EMG activity. Facilitation of forearm EMG activity ICC ranges from 0.52 to 0.83, indicating fair to high reliability before intervention in both limbs. Facilitation of forearm muscles is higher in the paretic as compared to the healthy limb (p<0.001). Upper arm FMA scores predict facilitation of forearm muscles after intervention in both groups (significant correlations ranged from R = 0.752, p = 0.002 to R = 0.779, p = 0.001), but only in the experimental group upper arm FMA scores predict changes in facilitation of forearm muscles after intervention (R = 0.709, p = 0.002; R = 0.827, p<0.001). Residual upper arm motor function primes recruitment of paralyzed forearm muscles in chronic stroke patients and predicts changes in their recruitment after BMI training. This study suggests that changes in upper arm-forearm synergies contribute to stroke motor recovery, and provides candidacy guidelines for similar BMI-based clinical practice.

An in vitro evaluation of the integrity of stainless steel crown margins cemented with different luting agents.

PubMed

Ettinger, R L; Kambhu, P P; Asmussen, C M; Damiano, P C

1998-01-01

The elderly population is retaining more teeth which require extensive restorations. The purpose of this study was to identify a luting agent which had the least marginal breakdown when used with stainless steel crowns. Thirty-six caries-free molars were selected, prepared for stainless steel crowns, and embedded in acrylic to support the crown and tooth. The crowns (Unitek/3M) were cemented with 4 different luting agents: (A) Fleck's Cement, (B) Ketac-Cem, (C) All-Bond C & B Cement, and (D) Panavia EX Cement. All the restored teeth were thermocycled and divided into 3 experimental groups. Twelve teeth were stained. The remaining teeth were occlusally loaded and stained. The remaining 12 teeth were thermocycled and stained again. The stainless steel crowns were then sectioned and photographed at 7.5x mag. The dye penetration was evaluated by measurement of the percentage of dye penetration from the crown margin to the cusp tip on each side. Statistical analysis found that the least dye penetration was with All-Bond C & B Cement (p = 0.0001). The most extensive penetration was observed in Ketac-Cem Occlusal loading was a significant factor (p = 0.0001) increasing the dye penetration, but the crown-tooth gap was not.

Analysis of castellated steel beam with oval openings

NASA Astrophysics Data System (ADS)

Tudjono, S.; Sunarto; Han, A. L.

2017-11-01

A castellated steel beam is per definition a wide flange (WF) or I shaped steel profile with openings, to reduce self-weight and improve the effectiveness in terms of material use. Recently, extensive study on these castellated steel beams has been conducted, involving different shapes in web openings. The main goal of these research works was to evaluate and analyze its optimum opening sizes and shapes configuration. More in-depth research work to the behavior and the influence of holes to WF beams need to be conducted. In this paper, an oval shaped web opening is chosen as alternate. The study involves a modification in the variation of oval web openings both in the horizontally and vertically direction. An experimental and numerical study based on the finite element method conducted with the Abaqus/CAE 6.12 software is used to analyze the buckling behavior of the web. The obtained results from the experimental test specimens are in good agreement with the obtained results from the finite element analysis. Furthermore, the numerical model can be expanded to be used as analyzing tool in evaluating and studying the effect and influencing factors of a variation in opening’s parameters.

Effect of a mind-body therapeutic program for infertile women repeating in vitro fertilization treatment on uncertainty, anxiety, and implantation rate.

PubMed

Kim, Miok; Kim, Sue; Chang, Soon-bok; Yoo, Ji-Soo; Kim, Hee Kyung; Cho, Jung Hyun

2014-03-01

The study aimed to develop a mind-body therapeutic program and evaluate its effects on mitigating uncertainty, anxiety, and implantation rate of second-trial in vitro fertilization (IVF) women. This study employed a nonequivalent control group nonsynchronized design. The conceptual framework and program content were developed from a preliminary survey of eight infertile women and the extensive review of the literature. Program focuses on three uncertainty-induced anxieties in infertile women: cognitive, emotional, and biological responses. To evaluate the effect of the intervention, the infertile women with unknown cause preparing for a second IVF treatment were sampled at convenience (26 experimental and 24 control). The experimental group in the study showed greater decrease in uncertainty and anxiety in premeasurements and postmeasurements than the control group did. However, no statistically significant differences in the implantation rate between groups were observed. This study is meaningful as the first intervention program for alleviating uncertainty and anxiety provided during the IVF treatment process. The positive effects of the mind-body therapeutic program in alleviating both uncertainty and anxiety have direct meaning for clinical applications. Copyright © 2014. Published by Elsevier B.V.

Investigation Study on Determination of Fracture Strain and Fractuer Forming Limit Curve Using Different Experimental and Numerical Methods

NASA Astrophysics Data System (ADS)

Farahnak, P.; Urbanek, M.; Džugan, J.

2017-09-01

Forming Limit Curve (FLC) is a well-known tool for the evaluation of failure in sheet metal process. However, its experimental determination and evaluation are rather complex. From theoretical point of view, FLC describes initiation of the instability not fracture. During the last years Digital Image Correlation (DIC) techniques have been developed extensively. Throughout this paper, all the measurements were done using DIC and as it is reported in the literature, different approaches to capture necking and fracture phenomena using Cross Section Method (CSM), Time dependent Method (TDM) and Thinning Method (TM) were investigated. Each aforementioned method has some advantages and disadvantages. Moreover, a cruciform specimen was used in order to cover whole FLC in the range between uniaxial to equi-biaxial tension and as an alternative for Nakajima test. Based on above-mentioned uncertainty about the fracture strain, some advanced numerical failure models can describe necking and fracture phenomena accurately with consideration of anisotropic effects. It is noticeable that in this paper, dog-bone, notch and circular disk specimens are used to calibrate Johnson-Cook (J-C) fracture model. The results are discussed for mild steel DC01.

Experimental study of improved rheology and lubricity of drilling fluids enhanced with nano-particles

NASA Astrophysics Data System (ADS)

Bég, O. Anwar; Espinoza, D. E. Sanchez; Kadir, Ali; Shamshuddin, MD.; Sohail, Ayesha

2018-04-01

An experimental study of the rheology and lubricity properties of a drilling fluid is reported, motivated by applications in highly deviated and extended reach wells. Recent developments in nanofluids have identified that the judicious injection of nano-particles into working drilling fluids may resolve a number of issues including borehole instability, lost circulation, torque and drag, pipe sticking problems, bit balling and reduction in drilling speed. The aim of this article is, therefore, to evaluate the rheological characteristics and lubricity of different nano-particles in water-based mud, with the potential to reduce costs via a decrease in drag and torque during the construction of highly deviated and ERD wells. Extensive results are presented for percentage in torque variation and coefficient of friction before and after aging. Rheology is evaluated via apparent viscosity, plastic viscosity and gel strength variation before and after aging for water-based muds (WBM). Results are included for silica and titanium nano-particles at different concentrations. These properties were measured before and after aging the mud samples at 80 °C during 16 h at static conditions. The best performance was shown with titanium nano-particles at a concentration of 0.60% (w/w) before aging.

A simple analytical method for determining the atmospheric dispersion of upward-directed high velocity releases

NASA Astrophysics Data System (ADS)

Palazzi, E.

The evaluation of atmospheric dispersion of a cloud, arising from a sudden release of flammable or toxic materials, is an essential tool for properly designing flares, vents and other safety devices and to quantify the potential risk related to the existing ones or arising from the various kinds of accidents which can occur in chemical plants. Among the methods developed to treat the important case of upward-directed jets, Hoehne's procedure for determining the behaviour and extent of flammability zone is extensively utilized, particularly concerning petrochemical plants. In a previous study, a substantial simplification of the aforesaid procedure was achieved, by correlating the experimental data with an empirical formula, allowing to obtain a mathematical description of the boundaries of the flammable cloud. Following a theoretical approach, a most general model is developed in the present work, applicable to the various kinds of design problems and/or risk evaluation regarding upward-directed releases from high velocity sources. It is also demonstrated that the model gives conservative results, if applied outside the range of the Hoehne's experimental conditions. Moreover, with simple modifications, the same approach could be easily applied to deal with the atmospheric dispersion of anyhow directed releases.

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer.

PubMed

Alamgeer, Muhammad; Neil Watkins, D; Banakh, Ilia; Kumar, Beena; Gough, Daniel J; Markman, Ben; Ganju, Vinod

2018-04-01

Preclinical studies in small cell lung cancer (SCLC) have shown that hyaluronic acid (HA) can be effectively used to deliver chemotherapy and selectively decrease CD44 expressing (stem cell-like) tumour cells. The current study aimed to replicate these findings and obtain data on safety and activity of HA-irinotecan (HA-IR). Eligible patients with extensive stage SCLC were consented. A safety cohort (n = 5) was treated with HA-IR and Carboplatin (C). Subsequently, the patients were randomised 1:1 to receive experimental (HA-IR + C) or standard (IR + C) treatment, to a maximum of 6 cycles. The second line patients were added to the study and treated with open label HA-IR + C. Tumour response was measured after every 2 cycles. Baseline tumour specimens were stained for CD44s and CD44v6 expression. Circulating tumour cells (CTCs) were enumerated before each treatment cycle. Out of 39 patients screened, 34 were evaluable for the study. The median age was 66 (range 39-83). The overall response rates were 69% and 75% for experimental and standard arms respectively. Median progression free survival was 42 and 28 weeks, respectively (p = 0.892). The treatments were well tolerated. The incidence of grade III/IV diarrhea was more common in the standard arm, while anaemia was more common in the experimental arm. IHC analysis suggested that the patients with CD44s positive tumours may gain survival benefit from HA-IR. HA-IR is well tolerated and active in ES-SCLC. The effect of HA-IR on CD44s + cancer stem-like cells provide an early hint towards a potential novel target.

Two-Stage Categorization in Brand Extension Evaluation: Electrophysiological Time Course Evidence

PubMed Central

Wang, Xiaoyi

2014-01-01

A brand name can be considered a mental category. Similarity-based categorization theory has been used to explain how consumers judge a new product as a member of a known brand, a process called brand extension evaluation. This study was an event-related potential study conducted in two experiments. The study found a two-stage categorization process reflected by the P2 and N400 components in brand extension evaluation. In experiment 1, a prime–probe paradigm was presented in a pair consisting of a brand name and a product name in three conditions, i.e., in-category extension, similar-category extension, and out-of-category extension. Although the task was unrelated to brand extension evaluation, P2 distinguished out-of-category extensions from similar-category and in-category ones, and N400 distinguished similar-category extensions from in-category ones. In experiment 2, a prime–probe paradigm with a related task was used, in which product names included subcategory and major-category product names. The N400 elicited by subcategory products was more significantly negative than that elicited by major-category products, with no salient difference in P2. We speculated that P2 could reflect the early low-level and similarity-based processing in the first stage, whereas N400 could reflect the late analytic and category-based processing in the second stage. PMID:25438152

Enhancing Extensive Reading with Data-Driven Learning

ERIC Educational Resources Information Center

Hadley, Gregory; Charles, Maggie

2017-01-01

This paper investigates using data-driven learning (DDL) as a means of stimulating greater lexicogrammatical knowledge and reading speed among lower proficiency learners in an extensive reading program. For 16 weekly 90-minute sessions, an experimental group (12 students) used DDL materials created from a corpus developed from the Oxford Bookworms…

The key roles of four Experimental Forests in the LTSP International Research Program

Treesearch

Robert F. Powers; Robert Denner; John D. Elioff; Gary O. Fiddler; Deborah Page-Dumroese; Felix Ponder; Allan E. Tiarks; Peter E. Avers; Richard G. Cline; Nelson S. Loftus

2014-01-01

Four Experimental Forests were pivotal in piloting the long-term soil productivity (LTSP) cooperative research program - one of the most successful and extensive collaborative science efforts yet undertaken by the USDA Forest Service. Launched on the Palustris, Challenge, Marcell, and Priest River Experimental Forests, LTSP traces to a seminal discussion during a field...

Simulations of 3D bioprinting: predicting bioprintability of nanofibrillar inks.

PubMed

Göhl, Johan; Markstedt, Kajsa; Mark, Andreas; Håkansson, Karl; Gatenholm, Paul; Edelvik, Fredrik

2018-06-18

3D bioprinting with cell containing bioinks show great promise in the biofabrication of patient specific tissue constructs. To fulfil the multiple requirements of a bioink, a wide range of materials and bioink composition are being developed and evaluated with regard to cell viability, mechanical performance and printability. It is essential that the printability and printing fidelity is not neglected since failure in printing the targeted architecture may be catastrophic for the survival of the cells and consequently the function of the printed tissue. However, experimental evaluation of bioinks printability is time-consuming and must be kept at a minimum, especially when 3D bioprinting with cells that are valuable and costly. This paper demonstrates how experimental evaluation could be complemented with computer based simulations to evaluate newly developed bioinks. Here, a computational fluid dynamics simulation tool was used to study the influence of different printing parameters and evaluate the predictability of the printing process. Based on data from oscillation frequency measurements of the evaluated bioinks, a full stress rheology model was used, where the viscoelastic behaviour of the material was captured. Simulation of the 3D bioprinting process is a powerful tool and will help in reducing the time and cost in the development and evaluation of bioinks. Moreover, it gives the opportunity to isolate parameters such as printing speed, nozzle height, flow rate and printing path to study their influence on the printing fidelity and the viscoelastic stresses within the bioink. The ability to study these features more extensively by simulating the printing process will result in a better understanding of what influences the viability of cells in 3D bioprinted tissue constructs.

The Role of Extension Nutrition Education in Student Achievement of Nutrition Standards in Grades K-3: A Descriptive Evaluation of a School-Based Program

ERIC Educational Resources Information Center

Arnold, Mary E.; Schreiber, Debera

2012-01-01

This article reports the results of a descriptive evaluation of the impact of an in-school Extension nutrition education program in a small, very rural county. The evaluation focused on understanding the nature of the role the Extension educator plays in delivering nutrition education, the impact of the program on student learning and achievement…

Experimental Characterization and Micromechanical Modeling of Woven Carbon/Copper Composites

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Pauly, Christopher C.; Pindera, Marek-Jerzy

1997-01-01

The results of an extensive experimental characterization and a preliminary analytical modeling effort for the elastoplastic mechanical behavior of 8-harness satin weave carbon/copper (C/Cu) composites are presented. Previous experimental and modeling investigations of woven composites are discussed, as is the evolution of, and motivation for, the continuing research on C/Cu composites. Experimental results of monotonic and cyclic tension, compression, and Iosipescu shear tests, and combined tension-compression tests, are presented. With regard to the test results, emphasis is placed on the effect of strain gauge size and placement, the effect of alloying the copper matrix to improve fiber-matrix bonding, yield surface characterization, and failure mechanisms. The analytical methodology used in this investigation consists of an extension of the three-dimensional generalized method of cells (GMC-3D) micromechanics model, developed by Aboudi (1994), to include inhomogeneity and plasticity effects on the subcell level. The extension of the model allows prediction of the elastoplastic mechanical response of woven composites, as represented by a true repeating unit cell for the woven composite. The model is used to examine the effects of refining the representative geometry of the composite, altering the composite overall fiber volume fraction, changing the size and placement of the strain gauge with respect to the composite's reinforcement weave, and including porosity within the infiltrated fiber yarns on the in-plane elastoplastic tensile, compressive, and shear response of 8-harness satin C/Cu. The model predictions are also compared with the appropriate monotonic experimental results.

Performance Evaluation of Extension Education Centers in Universities Based on the Balanced Scorecard

ERIC Educational Resources Information Center

Wu, Hung-Yi; Lin, Yi-Kuei; Chang, Chi-Hsiang

2011-01-01

This study aims at developing a set of appropriate performance evaluation indices mainly based on balanced scorecard (BSC) for extension education centers in universities by utilizing multiple criteria decision making (MCDM). Through literature reviews and experts who have real practical experiences in extension education, adequate performance…

Multiple Year Extension Program Outcomes & Impacts through Evaluation

ERIC Educational Resources Information Center

Hachfeld, Gary A.; Bau, David B.; Holcomb, C. Robert; Craig, J. William

2013-01-01

Dwindling public funding as well as greater competition for grant dollars create a challenge for Extension. For Extension to remain a financially viable organization, educators have to be able to produce substantive, measurable program outcomes and impacts. Evaluative data can inform program development and delivery, and helps administrators…

Extension Sustainability Camp: Design, Implementation, and Evaluation

ERIC Educational Resources Information Center

Brain, Roslynn; Upton, Sally; Tingey, Brett

2015-01-01

Sustainability Camps provide an opportunity for Extension educators to be in the forefront of sustainability outreach and to meet the growing demand for sustainability education. This article shares development, implementation, and evaluation of an Extension Sustainability Camp for youth, grades 4-6. Camp impact was measured via daily pre-and…

14 CFR § 1274.905 - Rights in data.

Code of Federal Regulations, 2014 CFR

2014-01-01

... collaborative research, experimental, developmental, engineering, demonstration, or design activities are to be... under the agreement. If cost sharing is unequal or no extensive research, experimental, developmental, engineering, demonstration, or design activities are likely, a different set of provisions may be appropriate...

Making Evaluation Work for You: Ideas for Deriving Multiple Benefits from Evaluation

ERIC Educational Resources Information Center

Jayaratne, K. S. U.

2016-01-01

Increased demand for accountability has forced Extension educators to evaluate their programs and document program impacts. Due to this situation, some Extension educators may view evaluation simply as the task, imposed on them by administrators, of collecting outcome and impact data for accountability. They do not perceive evaluation as a useful…

Two-phase flow characterization based on advanced instrumentation, neural networks, and mathematical modeling

NASA Astrophysics Data System (ADS)

Mi, Ye

1998-12-01

The major objective of this thesis is focused on theoretical and experimental investigations of identifying and characterizing vertical and horizontal flow regimes in two-phase flows. A methodology of flow regime identification with impedance-based neural network systems and a comprehensive model of vertical slug flow have been developed. Vertical slug flow has been extensively investigated and characterized with geometric, kinematic and hydrodynamic parameters. A multi-sensor impedance void-meter and a multi-sensor magnetic flowmeter were developed. The impedance void-meter was cross-calibrated with other reliable techniques for void fraction measurements. The performance of the impedance void-meter to measure the void propagation velocity was evaluated by the drift flux model. It was proved that the magnetic flowmeter was applicable to vertical slug flow measurements. Separable signals from these instruments allow us to unearth most characteristics of vertical slug flow. A methodology of vertical flow regime identification was developed. Supervised neural network and self-organizing neural network systems were employed. First, they were trained with results from an idealized simulation of impedance in a two-phase mixture. The simulation was mainly based on Mishima and Ishii's flow regime map, the drift flux model, and the newly developed model of slug flow. Then, these trained systems were tested with impedance signals. The results showed that the neural network systems were appropriate classifiers of vertical flow regimes. The theoretical models and experimental databases used in the simulation were reliable. Furthermore, this approach was applied successfully to horizontal flow identification. A comprehensive model was developed to predict important characteristics of vertical slug flow. It was realized that the void fraction of the liquid slug is determined by the relative liquid motion between the Taylor bubble tail and the Taylor bubble wake. Relying on this understanding and experimental results, a special relationship was built for the void fraction of the liquid slug. The prediction of the void fraction of the liquid slug was considerably improved. Experimental characterization of vertical slug flows was performed extensively with the impedance void-meter and the magnetic flowmeter. The theoretical predictions were compared with the experimental results. The agreements between them are very satisfactory.

Calculated X-ray Intensities Using Monte Carlo Algorithms: A Comparison to Experimental EPMA Data

NASA Technical Reports Server (NTRS)

Carpenter, P. K.

2005-01-01

Monte Carlo (MC) modeling has been used extensively to simulate electron scattering and x-ray emission from complex geometries. Here are presented comparisons between MC results and experimental electron-probe microanalysis (EPMA) measurements as well as phi(rhoz) correction algorithms. Experimental EPMA measurements made on NIST SRM 481 (AgAu) and 482 (CuAu) alloys, at a range of accelerating potential and instrument take-off angles, represent a formal microanalysis data set that has been widely used to develop phi(rhoz) correction algorithms. X-ray intensity data produced by MC simulations represents an independent test of both experimental and phi(rhoz) correction algorithms. The alpha-factor method has previously been used to evaluate systematic errors in the analysis of semiconductor and silicate minerals, and is used here to compare the accuracy of experimental and MC-calculated x-ray data. X-ray intensities calculated by MC are used to generate a-factors using the certificated compositions in the CuAu binary relative to pure Cu and Au standards. MC simulations are obtained using the NIST, WinCasino, and WinXray algorithms; derived x-ray intensities have a built-in atomic number correction, and are further corrected for absorption and characteristic fluorescence using the PAP phi(rhoz) correction algorithm. The Penelope code additionally simulates both characteristic and continuum x-ray fluorescence and thus requires no further correction for use in calculating alpha-factors.

Evaluation of the immunogenicity of an experimental subunit vaccine that allows differentiation between infected and vaccinated animals against bluetongue virus serotype 8 in cattle.

PubMed

Anderson, Jenna; Hägglund, Sara; Bréard, Emmanuel; Comtet, Loic; Lövgren Bengtsson, Karin; Pringle, John; Zientara, Stéphan; Valarcher, Jean Francois

2013-08-01

Bluetongue virus (BTV), the causative agent of bluetongue in ruminants, is an emerging virus in northern Europe. The 2006 outbreak of BTV serotype 8 (BTV-8) in Europe was marked by an unusual teratogenic effect and a high frequency of clinical signs in cattle. Conventional control strategies targeting small ruminants were therefore extended to include cattle. Since cattle were not routinely vaccinated before 2006, the immune responses to BTV have not been studied extensively in this species. With the aims of developing a subunit vaccine against BTV-8 for differentiation between infected and vaccinated animals based on viral protein 7 (VP7) antibody detection and of improving the current understanding of the immunogenicity of BTV proteins in cattle, the immune responses induced by recombinant VP2 (BTV-8) and nonstructural protein 1 (NS1) and NS2 (BTV-2) were studied. Cows were immunized twice (with a 3-week interval) with the experimental vaccine, a commercial inactivated vaccine, or a placebo. The two vaccines induced similar neutralizing antibody responses to BTV-8. Furthermore, the antibody responses detected against VP2, NS1, and NS2 were strongest in the animals immunized with the experimental vaccine, and for the first time, a serotype cross-reactive antibody response to NS2 was shown in cattle vaccinated with the commercial vaccine. The two vaccines evoked measurable T cell responses against NS1, thereby supporting a bovine cross-reactive T cell response. Finally, VP7 seroconversion was observed after vaccination with the commercial vaccine, as in natural infections, but not after vaccination with the experimental vaccine, indicating that the experimental vaccine may allow the differentiation of vaccinated animals from infected animals regardless of BTV serotype. The experimental vaccine will be further evaluated during a virulent challenge in a high-containment facility.

Evaluation of the Immunogenicity of an Experimental Subunit Vaccine That Allows Differentiation between Infected and Vaccinated Animals against Bluetongue Virus Serotype 8 in Cattle

PubMed Central

Hägglund, Sara; Bréard, Emmanuel; Comtet, Loic; Lövgren Bengtsson, Karin; Pringle, John; Zientara, Stéphan

2013-01-01

Bluetongue virus (BTV), the causative agent of bluetongue in ruminants, is an emerging virus in northern Europe. The 2006 outbreak of BTV serotype 8 (BTV-8) in Europe was marked by an unusual teratogenic effect and a high frequency of clinical signs in cattle. Conventional control strategies targeting small ruminants were therefore extended to include cattle. Since cattle were not routinely vaccinated before 2006, the immune responses to BTV have not been studied extensively in this species. With the aims of developing a subunit vaccine against BTV-8 for differentiation between infected and vaccinated animals based on viral protein 7 (VP7) antibody detection and of improving the current understanding of the immunogenicity of BTV proteins in cattle, the immune responses induced by recombinant VP2 (BTV-8) and nonstructural protein 1 (NS1) and NS2 (BTV-2) were studied. Cows were immunized twice (with a 3-week interval) with the experimental vaccine, a commercial inactivated vaccine, or a placebo. The two vaccines induced similar neutralizing antibody responses to BTV-8. Furthermore, the antibody responses detected against VP2, NS1, and NS2 were strongest in the animals immunized with the experimental vaccine, and for the first time, a serotype cross-reactive antibody response to NS2 was shown in cattle vaccinated with the commercial vaccine. The two vaccines evoked measurable T cell responses against NS1, thereby supporting a bovine cross-reactive T cell response. Finally, VP7 seroconversion was observed after vaccination with the commercial vaccine, as in natural infections, but not after vaccination with the experimental vaccine, indicating that the experimental vaccine may allow the differentiation of vaccinated animals from infected animals regardless of BTV serotype. The experimental vaccine will be further evaluated during a virulent challenge in a high-containment facility. PMID:23720365

RIPL - Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations

NASA Astrophysics Data System (ADS)

Capote, R.; Herman, M.; Obložinský, P.; Young, P. G.; Goriely, S.; Belgya, T.; Ignatyuk, A. V.; Koning, A. J.; Hilaire, S.; Plujko, V. A.; Avrigeanu, M.; Bersillon, O.; Chadwick, M. B.; Fukahori, T.; Ge, Zhigang; Han, Yinlu; Kailas, S.; Kopecky, J.; Maslov, V. M.; Reffo, G.; Sin, M.; Soukhovitskii, E. Sh.; Talou, P.

2009-12-01

We describe the physics and data included in the Reference Input Parameter Library, which is devoted to input parameters needed in calculations of nuclear reactions and nuclear data evaluations. Advanced modelling codes require substantial numerical input, therefore the International Atomic Energy Agency (IAEA) has worked extensively since 1993 on a library of validated nuclear-model input parameters, referred to as the Reference Input Parameter Library (RIPL). A final RIPL coordinated research project (RIPL-3) was brought to a successful conclusion in December 2008, after 15 years of challenging work carried out through three consecutive IAEA projects. The RIPL-3 library was released in January 2009, and is available on the Web through http://www-nds.iaea.org/RIPL-3/. This work and the resulting database are extremely important to theoreticians involved in the development and use of nuclear reaction modelling (ALICE, EMPIRE, GNASH, UNF, TALYS) both for theoretical research and nuclear data evaluations. The numerical data and computer codes included in RIPL-3 are arranged in seven segments: MASSES contains ground-state properties of nuclei for about 9000 nuclei, including three theoretical predictions of masses and the evaluated experimental masses of Audi et al. (2003). DISCRETE LEVELS contains 117 datasets (one for each element) with all known level schemes, electromagnetic and γ-ray decay probabilities available from ENSDF in October 2007. NEUTRON RESONANCES contains average resonance parameters prepared on the basis of the evaluations performed by Ignatyuk and Mughabghab. OPTICAL MODEL contains 495 sets of phenomenological optical model parameters defined in a wide energy range. When there are insufficient experimental data, the evaluator has to resort to either global parameterizations or microscopic approaches. Radial density distributions to be used as input for microscopic calculations are stored in the MASSES segment. LEVEL DENSITIES contains phenomenological parameterizations based on the modified Fermi gas and superfluid models and microscopic calculations which are based on a realistic microscopic single-particle level scheme. Partial level densities formulae are also recommended. All tabulated total level densities are consistent with both the recommended average neutron resonance parameters and discrete levels. GAMMA contains parameters that quantify giant resonances, experimental gamma-ray strength functions and methods for calculating gamma emission in statistical model codes. The experimental GDR parameters are represented by Lorentzian fits to the photo-absorption cross sections for 102 nuclides ranging from 51V to 239Pu. FISSION includes global prescriptions for fission barriers and nuclear level densities at fission saddle points based on microscopic HFB calculations constrained by experimental fission cross sections.

RIPL - Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Capote, R.; Herman, M.; Oblozinsky, P.

We describe the physics and data included in the Reference Input Parameter Library, which is devoted to input parameters needed in calculations of nuclear reactions and nuclear data evaluations. Advanced modelling codes require substantial numerical input, therefore the International Atomic Energy Agency (IAEA) has worked extensively since 1993 on a library of validated nuclear-model input parameters, referred to as the Reference Input Parameter Library (RIPL). A final RIPL coordinated research project (RIPL-3) was brought to a successful conclusion in December 2008, after 15 years of challenging work carried out through three consecutive IAEA projects. The RIPL-3 library was released inmore » January 2009, and is available on the Web through (http://www-nds.iaea.org/RIPL-3/). This work and the resulting database are extremely important to theoreticians involved in the development and use of nuclear reaction modelling (ALICE, EMPIRE, GNASH, UNF, TALYS) both for theoretical research and nuclear data evaluations. The numerical data and computer codes included in RIPL-3 are arranged in seven segments: MASSES contains ground-state properties of nuclei for about 9000 nuclei, including three theoretical predictions of masses and the evaluated experimental masses of Audi et al. (2003). DISCRETE LEVELS contains 117 datasets (one for each element) with all known level schemes, electromagnetic and {gamma}-ray decay probabilities available from ENSDF in October 2007. NEUTRON RESONANCES contains average resonance parameters prepared on the basis of the evaluations performed by Ignatyuk and Mughabghab. OPTICAL MODEL contains 495 sets of phenomenological optical model parameters defined in a wide energy range. When there are insufficient experimental data, the evaluator has to resort to either global parameterizations or microscopic approaches. Radial density distributions to be used as input for microscopic calculations are stored in the MASSES segment. LEVEL DENSITIES contains phenomenological parameterizations based on the modified Fermi gas and superfluid models and microscopic calculations which are based on a realistic microscopic single-particle level scheme. Partial level densities formulae are also recommended. All tabulated total level densities are consistent with both the recommended average neutron resonance parameters and discrete levels. GAMMA contains parameters that quantify giant resonances, experimental gamma-ray strength functions and methods for calculating gamma emission in statistical model codes. The experimental GDR parameters are represented by Lorentzian fits to the photo-absorption cross sections for 102 nuclides ranging from {sup 51}V to {sup 239}Pu. FISSION includes global prescriptions for fission barriers and nuclear level densities at fission saddle points based on microscopic HFB calculations constrained by experimental fission cross sections.« less

RIPL-Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Capote, R.; Herman, M.; Capote,R.

We describe the physics and data included in the Reference Input Parameter Library, which is devoted to input parameters needed in calculations of nuclear reactions and nuclear data evaluations. Advanced modelling codes require substantial numerical input, therefore the International Atomic Energy Agency (IAEA) has worked extensively since 1993 on a library of validated nuclear-model input parameters, referred to as the Reference Input Parameter Library (RIPL). A final RIPL coordinated research project (RIPL-3) was brought to a successful conclusion in December 2008, after 15 years of challenging work carried out through three consecutive IAEA projects. The RIPL-3 library was released inmore » January 2009, and is available on the Web through http://www-nds.iaea.org/RIPL-3/. This work and the resulting database are extremely important to theoreticians involved in the development and use of nuclear reaction modelling (ALICE, EMPIRE, GNASH, UNF, TALYS) both for theoretical research and nuclear data evaluations. The numerical data and computer codes included in RIPL-3 are arranged in seven segments: MASSES contains ground-state properties of nuclei for about 9000 nuclei, including three theoretical predictions of masses and the evaluated experimental masses of Audi et al. (2003). DISCRETE LEVELS contains 117 datasets (one for each element) with all known level schemes, electromagnetic and {gamma}-ray decay probabilities available from ENSDF in October 2007. NEUTRON RESONANCES contains average resonance parameters prepared on the basis of the evaluations performed by Ignatyuk and Mughabghab. OPTICAL MODEL contains 495 sets of phenomenological optical model parameters defined in a wide energy range. When there are insufficient experimental data, the evaluator has to resort to either global parameterizations or microscopic approaches. Radial density distributions to be used as input for microscopic calculations are stored in the MASSES segment. LEVEL DENSITIES contains phenomenological parameterizations based on the modified Fermi gas and superfluid models and microscopic calculations which are based on a realistic microscopic single-particle level scheme. Partial level densities formulae are also recommended. All tabulated total level densities are consistent with both the recommended average neutron resonance parameters and discrete levels. GAMMA contains parameters that quantify giant resonances, experimental gamma-ray strength functions and methods for calculating gamma emission in statistical model codes. The experimental GDR parameters are represented by Lorentzian fits to the photo-absorption cross sections for 102 nuclides ranging from {sup 51}V to {sup 239}Pu. FISSION includes global prescriptions for fission barriers and nuclear level densities at fission saddle points based on microscopic HFB calculations constrained by experimental fission cross sections.« less

Creep and Oxidation of Hafnium Diboride Based Ultra High Temperature Ceramics at 1500C

DTIC Science & Technology

2015-12-01

through experimentation. Although the Literature Review showed that some theories and models have been developed based on extensive experimental results...of Some Refractory Metals & Ceramics [Fahrenholtz] ........... 14 Figure 4: Creep Strain vs Time Based on Burgers Model ...

75 FR 20874 - Agency Information Collection Activity Seeking OMB Approval

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... to issue Experimental Permits for reusable suborbital rockets to authorize launches for the purpose... Suborbital Rockets. Type of Request: Extension without change of a currently approved collection. OMB Control... FAA's new authority to issue Experimental Permits for reusable [[Page 20875

47 CFR 74.102 - Uses of experimental broadcast stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Section 74.102 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... station will be issued for the purposes of carrying on research and experimentation for the development and advancement of new broadcast technology, equipment, systems or services which are more extensive...

47 CFR 74.102 - Uses of experimental broadcast stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 74.102 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... station will be issued for the purposes of carrying on research and experimentation for the development and advancement of new broadcast technology, equipment, systems or services which are more extensive...

47 CFR 74.102 - Uses of experimental broadcast stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 74.102 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES... station will be issued for the purposes of carrying on research and experimentation for the development and advancement of new broadcast technology, equipment, systems or services which are more extensive...

Analytical and Experimental Performance Evaluation of BLE Neighbor Discovery Process Including Non-Idealities of Real Chipsets

PubMed Central

Perez-Diaz de Cerio, David; Hernández, Ángela; Valenzuela, Jose Luis; Valdovinos, Antonio

2017-01-01

The purpose of this paper is to evaluate from a real perspective the performance of Bluetooth Low Energy (BLE) as a technology that enables fast and reliable discovery of a large number of users/devices in a short period of time. The BLE standard specifies a wide range of configurable parameter values that determine the discovery process and need to be set according to the particular application requirements. Many previous works have been addressed to investigate the discovery process through analytical and simulation models, according to the ideal specification of the standard. However, measurements show that additional scanning gaps appear in the scanning process, which reduce the discovery capabilities. These gaps have been identified in all of the analyzed devices and respond to both regular patterns and variable events associated with the decoding process. We have demonstrated that these non-idealities, which are not taken into account in other studies, have a severe impact on the discovery process performance. Extensive performance evaluation for a varying number of devices and feasible parameter combinations has been done by comparing simulations and experimental measurements. This work also includes a simple mathematical model that closely matches both the standard implementation and the different chipset peculiarities for any possible parameter value specified in the standard and for any number of simultaneous advertising devices under scanner coverage. PMID:28273801

Analytical and Experimental Performance Evaluation of BLE Neighbor Discovery Process Including Non-Idealities of Real Chipsets.

PubMed

Perez-Diaz de Cerio, David; Hernández, Ángela; Valenzuela, Jose Luis; Valdovinos, Antonio

2017-03-03

The purpose of this paper is to evaluate from a real perspective the performance of Bluetooth Low Energy (BLE) as a technology that enables fast and reliable discovery of a large number of users/devices in a short period of time. The BLE standard specifies a wide range of configurable parameter values that determine the discovery process and need to be set according to the particular application requirements. Many previous works have been addressed to investigate the discovery process through analytical and simulation models, according to the ideal specification of the standard. However, measurements show that additional scanning gaps appear in the scanning process, which reduce the discovery capabilities. These gaps have been identified in all of the analyzed devices and respond to both regular patterns and variable events associated with the decoding process. We have demonstrated that these non-idealities, which are not taken into account in other studies, have a severe impact on the discovery process performance. Extensive performance evaluation for a varying number of devices and feasible parameter combinations has been done by comparing simulations and experimental measurements. This work also includes a simple mathematical model that closely matches both the standard implementation and the different chipset peculiarities for any possible parameter value specified in the standard and for any number of simultaneous advertising devices under scanner coverage.

Online Extensive Reading for Advanced Foreign Language Learners: An Evaluation Study

ERIC Educational Resources Information Center

Arnold, Nike

2009-01-01

The following article reports the findings of a qualitative evaluation of an online extensive reading program in German as a foreign language. Designed for advanced learners, it differs from traditional extensive reading programs in two important aspects: students read online instead of printed materials, and there was no teacher preselection to…

A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke

PubMed Central

Maysami, Samaneh; Wong, Raymond; Pradillo, Jesus M; Denes, Adam; Dhungana, Hiramani; Malm, Tarja; Koistinaho, Jari; Orset, Cyrille; Rahman, Mahbubur; Rubio, Marina; Schwaninger, Markus; Vivien, Denis; Bath, Philip M; Rothwell, Nancy J

2015-01-01

Stroke represents a global challenge and is a leading cause of permanent disability worldwide. Despite much effort, translation of research findings to clinical benefit has not yet been successful. Failure of neuroprotection trials is considered, in part, due to the low quality of preclinical studies, low level of reproducibility across different laboratories and that stroke co-morbidities have not been fully considered in experimental models. More rigorous testing of new drug candidates in different experimental models of stroke and initiation of preclinical cross-laboratory studies have been suggested as ways to improve translation. However, to our knowledge, no drugs currently in clinical stroke trials have been investigated in preclinical cross-laboratory studies. The cytokine interleukin 1 is a key mediator of neuronal injury, and the naturally occurring interleukin 1 receptor antagonist has been reported as beneficial in experimental studies of stroke. In the present paper, we report on a preclinical cross-laboratory stroke trial designed to investigate the efficacy of interleukin 1 receptor antagonist in different research laboratories across Europe. Our results strongly support the therapeutic potential of interleukin 1 receptor antagonist in experimental stroke and provide further evidence that interleukin 1 receptor antagonist should be evaluated in more extensive clinical stroke trials. PMID:26661169

Optimality models in the age of experimental evolution and genomics.

PubMed

Bull, J J; Wang, I-N

2010-09-01

Optimality models have been used to predict evolution of many properties of organisms. They typically neglect genetic details, whether by necessity or design. This omission is a common source of criticism, and although this limitation of optimality is widely acknowledged, it has mostly been defended rather than evaluated for its impact. Experimental adaptation of model organisms provides a new arena for testing optimality models and for simultaneously integrating genetics. First, an experimental context with a well-researched organism allows dissection of the evolutionary process to identify causes of model failure--whether the model is wrong about genetics or selection. Second, optimality models provide a meaningful context for the process and mechanics of evolution, and thus may be used to elicit realistic genetic bases of adaptation--an especially useful augmentation to well-researched genetic systems. A few studies of microbes have begun to pioneer this new direction. Incompatibility between the assumed and actual genetics has been demonstrated to be the cause of model failure in some cases. More interestingly, evolution at the phenotypic level has sometimes matched prediction even though the adaptive mutations defy mechanisms established by decades of classic genetic studies. Integration of experimental evolutionary tests with genetics heralds a new wave for optimality models and their extensions that does not merely emphasize the forces driving evolution.

Modal Vibration Analysis of Large Castings

NASA Technical Reports Server (NTRS)

Werlink, Rudolph J.; Margasahayam, Ravi N.

2009-01-01

The art of experimental modal vibration analysis (MVA) has been extended to apply to large castings. This extension was made to enable the use of experimental MVA as a relatively inexpensive, simple means of assessing the internal structural integrity of tread shoes of crawler transporters used to move spacecraft to the launch pad at Kennedy Space Center. Each tread shoe is made from cast iron and weighs about a ton (has a mass .907 kg). The present extended version of experimental MVA could also be applied to other large castings. It could be especially useful to manufacturers as a means of rapidly discriminating against large castings that contain unacceptably large concentrations of internal defects. The use of experimental MVA to assess structural integrity is not new. What are new here are those aspects of the extension of experimental MVA that pertain to the application of MVA to objects so massive that it may not be practical or cost effective to mount them in special test fixtures that impose special test boundary conditions to test them in place under normal conditions of use.

Code Validation Studies of High-Enthalpy Flows

DTIC Science & Technology

2006-12-01

stage of future hypersonic vehicles. The development and design of such vehicles is aided by the use of experimentation and numerical simulation... numerical predictions and experimental measurements. 3. Summary of Previous Work We have studied extensively hypersonic double-cone flows with and in...the experimental measurements and the numerical predictions. When we accounted for that effect in numerical simulations, and also augmented the

The Effects of Extensive Reading and Reading Strategies on Reading Self-Efficacy

ERIC Educational Resources Information Center

Burrows, Lance

2012-01-01

This study is a quasi-experimental, longitudinal investigation into the role that extensive reading and reading strategies play in the cultivation of reading self-efficacy. Conducted over the course of one academic year, how changes in reading self-efficacy translate into changes in reading comprehension was examined. In addition, the…

PHENIX Muon Piston Calorimeter (MPC) APD and Prototype MPC Extension (MPC-EX) Tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lajoie, John

2013-06-20

This is a technical scope of work (TSW) between the Fermi National Accelerator Laboratory (Fermilab) and the experimenters of Muon Piston Calorimeter Extension (MPC-EX) Collaboration who have committed to participate in beam tests to be carried out during the 2013- 2014 Fermilab Test Beam Facility program.

Operational Axioms for Quantum Mechanics

DOE Office of Scientific and Technical Information (OSTI.GOV)

D'Ariano, Giacomo Mauro; Department of Electrical and Computer Engineering, Northwestern University, Evanston, IL 60208

2007-02-21

The mathematical formulation of Quantum Mechanics in terms of complex Hilbert space is derived for finite dimensions, starting from a general definition of physical experiment and from five simple Postulates concerning experimental accessibility and simplicity. For the infinite dimensional case, on the other hand, a C*-algebra representation of physical transformations is derived, starting from just four of the five Postulates via a Gelfand-Naimark-Segal (GNS) construction. The present paper simplifies and sharpens the previous derivation in Ref. [1]. The main ingredient of the axiomatization is the postulated existence of faithful states that allows one to calibrate the experimental apparatus. Such notionmore » is at the basis of the operational definitions of the scalar product and of the transposed of a physical transformation. What is new in the present paper with respect to Ref. [1], is the operational deduction of an involution corresponding to the complex-conjugation for effects, whose extension to transformations allows to define the adjoint of a transformation when the extension is composition-preserving. The existence of such composition-preserving extension among possible extensions is analyzed.« less

Design of a composite wing extension for a general aviation aircraft

NASA Technical Reports Server (NTRS)

Adney, P. S.; Horn, W. J.

1984-01-01

A composite wing extension was designed for a typical general aviation aircraft to improve lift curve slope, dihedral effect, and lift to drag ratio. Advanced composite materials were used in the design to evaluate their use as primary structural components in general aviation aircraft. Extensive wind tunnel tests were used to evaluate six extension shapes. The extension shape chosen as the best choice was 28 inches long with a total area of 17 square feet. Subsequent flight tests showed the wing extension's predicted aerodynamic improvements to be correct. The structural design of the wing extension consisted of a hybrid laminate carbon core with outer layers of Kevlar - layed up over a foam interior which acted as an internal support. The laminate skin of the wing extension was designed from strength requirements, and the foam core was included to prevent buckling. A joint lap was recommended to attach the wing extension to the main wing structure.

Small Scale Trace Contaminant Testing of SA9T at Ambient and Reduced Pressure Conditions

NASA Technical Reports Server (NTRS)

Broerman, Craig; Sweterlitsch, Jeffrey

2011-01-01

A principle concern for air revitalization technology in a closed loop system is the capability to control carbon dioxide (CO2) and humidity (H2O). An amine based sorbent technology, SA9T, has long been evaluated for use in this application and several programs are evaluating it for use in both a cabin as well as space suit applications. While the CO2 and H2O performance of the sorbent has been tested extensively, the question of how trace contaminants impact performance requires further evaluation. This paper presents experimental results of small scale SA9T testing that was performed over a variety of test conditions and with a variety of trace contaminants. Testing evaluated the ability of SA9T media to sufficiently remove CO2 and H2O after exposure to a fully saturated trace contaminant at ambient conditions. Testing also evaluated the impact of CO2 and H2O removal performance at suit loop pressures during cyclic operation with a constant inlet contaminant load. In addition, testing evaluated the performance of SA9T at ambient conditions in a continuous 30-day test with a mixed trace contaminant stream.

Experimental model: dye penetration of extensive interim restorations used during endodontic treatment while under load in a multiple axis chewing simulator.

PubMed

Jensen, Arna-Lee; Abbott, Paul V

2007-10-01

The purpose of this study was to design an experimental model that allowed extensive endodontic interim restorations to be tested for dye penetration while under simulated masticatory load. Extracted premolar teeth had standardized mesio-occluso-distal cavities prepared, and the root canals were instrumented. A cotton wool pellet was placed in the pulp chamber, and the cavities were restored with Cavit, IRM, Ketac-Fil Plus, Ketac-Silver, or composite resin (Z100). They were subjected to the equivalent of 3 months of clinical load while exposed to methylene blue dye. Results of this study could not support IRM as a suitable interim endodontic restorative material to use in extensive cavities. The dye penetration in the Ketac-Fil Plus and Ketac-Silver specimens was not predictable, and the results suggested Cavit and Z100 composite resin require further investigations as potentially useful materials for this purpose.

14 CFR 1274.905 - Rights in data.

Code of Federal Regulations, 2011 CFR

2011-01-01

... research, experimental, developmental, engineering, demonstration, or design activities are to be carried... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Rights in data. 1274.905 Section 1274.905... the agreement. If cost sharing is unequal or no extensive research, experimental, developmental...

An Experimental Investigation into Failure and Localization Phenomena in the Extension to Shear Fracture Transition in Rock

NASA Astrophysics Data System (ADS)

Choens, R. C., II; Chester, F. M.; Bauer, S. J.; Flint, G. M.

2014-12-01

Fluid-pressure assisted fracturing can produce mesh and other large, interconnected and complex networks consisting of both extension and shear fractures in various metamorphic, magmatic and tectonic systems. Presently, rock failure criteria for tensile and low-mean compressive stress conditions is poorly defined, although there is accumulating evidence that the transition from extension to shear fracture with increasing mean stress is continuous. We report on the results of experiments designed to document failure criteria, fracture mode, and localization phenomena for several rock types (sandstone, limestone, chalk and marble). Experiments were conducted in triaxial extension using a necked (dogbone) geometry to achieve mixed tension and compression stress states with local component-strain measurements in the failure region. The failure envelope for all rock types is similar, but are poorly described using Griffith or modified Griffith (Coulomb or other) failure criteria. Notably, the mode of fracture changes systematically from pure extension to shear with increase in compressive mean stress and display a continuous change in fracture orientation with respect to principal stress axes. Differential stress and inelastic strain show a systematic increase with increasing mean stress, whereas the axial stress decreases before increasing with increasing mean stress. The stress and strain data are used to analyze elastic and plastic strains leading to failure and compare the experimental results to predictions for localization using constitutive models incorporating on bifurcation theory. Although models are able to describe the stability behavior and onset of localization qualitatively, the models are unable to predict fracture type or orientation. Constitutive models using single or multiple yield surfaces are unable to predict the experimental results, reflecting the difficulty in capturing the changing micromechanisms from extension to shear failure. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Deopartment of Energy's National Security Administration under contract DE-AC04-94AL85000. SAND2014-16578A

Linearised and non-linearised isotherm models optimization analysis by error functions and statistical means

PubMed Central

2014-01-01

In adsorption study, to describe sorption process and evaluation of best-fitting isotherm model is a key analysis to investigate the theoretical hypothesis. Hence, numerous statistically analysis have been extensively used to estimate validity of the experimental equilibrium adsorption values with the predicted equilibrium values. Several statistical error analysis were carried out. In the present study, the following statistical analysis were carried out to evaluate the adsorption isotherm model fitness, like the Pearson correlation, the coefficient of determination and the Chi-square test, have been used. The ANOVA test was carried out for evaluating significance of various error functions and also coefficient of dispersion were evaluated for linearised and non-linearised models. The adsorption of phenol onto natural soil (Local name Kalathur soil) was carried out, in batch mode at 30 ± 20 C. For estimating the isotherm parameters, to get a holistic view of the analysis the models were compared between linear and non-linear isotherm models. The result reveled that, among above mentioned error functions and statistical functions were designed to determine the best fitting isotherm. PMID:25018878

Seismic risk assessment of Trani's Cathedral bell tower in Apulia, Italy

NASA Astrophysics Data System (ADS)

Diaferio, Mariella; Foti, Dora

2017-09-01

The present paper deals with the evaluation of the seismic vulnerability of slender historical buildings; these structures, in fact, may manifest a high risk with respect to seismic actions as usually they have been designed to resist to gravitational loads only, and are characterized by a high flexibility. To evaluate this behavior, the bell tower of the Trani's Cathedral is investigated. The tower is 57 m tall and is characterized by an unusual building typology, i.e., the walls are composed of a concrete core coupled with external masonry stones. The dynamic parameters and the mechanical properties of the tower have been evaluated on the basis of an extensive experimental campaign that made use of ambient vibration tests and ground penetrating radar tests. Such data have been utilized to calibrate a numerical model of the examined tower. A linear static analysis, a dynamic analysis and a nonlinear static analysis have been carried out on such model to evaluate the displacement capacity of the tower and the seismic risk assessment in accordance with the Italian guidelines.

Recent Efforts in Data Compilations for Nuclear Astrophysics

NASA Astrophysics Data System (ADS)

Dillmann, Iris

2008-05-01

Some recent efforts in compiling data for astrophysical purposes are introduced, which were discussed during a JINA-CARINA Collaboration meeting on ``Nuclear Physics Data Compilation for Nucleosynthesis Modeling'' held at the ECT* in Trento/Italy from May 29th-June 3rd, 2007. The main goal of this collaboration is to develop an updated and unified nuclear reaction database for modeling a wide variety of stellar nucleosynthesis scenarios. Presently a large number of different reaction libraries (REACLIB) are used by the astrophysics community. The ``JINA Reaclib Database'' on http://www.nscl.msu.edu/~nero/db/ aims to merge and fit the latest experimental stellar cross sections and reaction rate data of various compilations, e.g. NACRE and its extension for Big Bang nucleosynthesis, Caughlan and Fowler, Iliadis et al., and KADoNiS. The KADoNiS (Karlsruhe Astrophysical Database of Nucleosynthesis in Stars, http://nuclear-astrophysics.fzk.de/kadonis) project is an online database for neutron capture cross sections relevant to the s process. The present version v0.2 is already included in a REACLIB file from Basel university (http://download.nucastro.org/astro/reaclib). The present status of experimental stellar (n,γ) cross sections in KADoNiS is shown. It contains recommended cross sections for 355 isotopes between 1H and 210Bi, over 80% of them deduced from experimental data. A ``high priority list'' for measurements and evaluations for light charged-particle reactions set up by the JINA-CARINA collaboration is presented. The central web access point to submit and evaluate new data is provided by the Oak Ridge group via the http://www.nucastrodata.org homepage. ``Workflow tools'' aim to make the evaluation process transparent and allow users to follow the progress.

Supplementation with Silk Amino Acids improves physiological parameters defining stamina in elite fin-swimmers.

PubMed

Zubrzycki, Igor Z; Ossowski, Zbigniew; Przybylski, Stanislaw; Wiacek, Magdalena; Clarke, Anna; Trabka, Bartosz

2014-01-01

Previous animal study has shown that supplementation with silk amino acid hydrolysate (SAA) increases stamina in mice. The presented study was the first formal evaluation of the influence of SAA supplementation on parameters defining physiological fitness level in humans. It was a randomized controlled trial with a parallel-group design on elite male fin-swimmers. The experimental group was supplemented with 500 mg of SAA per kg of body mass, dissolved in 250 ml of a Carborade Drink®; the control group with Carborade Drink® alone; 3 times a day, 30 minutes prior to the training session. Changes discerned in the experimental group were more pronounced than those observed in the control group. For example, the change in the serum lactic acid concentration observed in the experimental group was sevenfold less than in the control group [21.8 vs. -3.7 L% for the control and experimental groups, respectively]. An analysis of a lactate profile as a function of a maximal swimming velocity exposed a statistically significant positive shift in the swimming velocity of 0.05 m/s, at the lactate concentration of 4 mmol/L in the experimental group. There was also a positive, although statistically insignificant, increase of 2.6 L% in serum testosterone levels in the experimental group. This study showed that a 12-day SAA supplementation combined with an extensive and rigorous training schedule was sufficient to increase an aerobic stamina. However, this phenomenon was associated with an augmented level of muscular damage (an increased level of creatine phosphokinase in the experimental group).

Torsional actuation with extension-torsion composite coupling and a magnetostrictive actuator

NASA Astrophysics Data System (ADS)

Bothwell, Christopher M.; Chandra, Ramesh; Chopra, Inderjit

1995-04-01

An analytical-experimental study of using magnetostrictive actuators in conjunction with an extension-torsion coupled composite tube to actuate a rotor blade trailing-edge flap to actively control helicopter vibration is presented. Thin walled beam analysis based on Vlasov theory was used to predict the induced twist and extension in a composite tube with magnetostrictive actuation. The study achieved good correlation between theory and experiment. The Kevlar-epoxy systems showed good correlation between measured and predicted twist values.

Using Maps in Web Analytics to Evaluate the Impact of Web-Based Extension Programs

ERIC Educational Resources Information Center

Veregin, Howard

2015-01-01

Maps can be a valuable addition to the Web analytics toolbox for Extension programs that use the Web to disseminate information. Extension professionals use Web analytics tools to evaluate program impacts. Maps add a unique perspective through visualization and analysis of geographic patterns and their relationships to other variables. Maps can…

Cost Effectiveness Ratio: Evaluation Tool for Comparing the Effectiveness of Similar Extension Programs

ERIC Educational Resources Information Center

Jayaratne, K. S. U.

2015-01-01

Extension educators have been challenged to be cost effective in their educational programming. The cost effectiveness ratio is a versatile evaluation indicator for Extension educators to compare the cost of achieving a unit of outcomes or educating a client in similar educational programs. This article describes the cost effectiveness ratio and…

INVESTIGATION INTO THE MECHANISMS OF TISSUE ATOMIZATION BY HIGH INTENSITY FOCUSED ULTRASOUND

PubMed Central

Simon, Julianna C.; Sapozhnikov, Oleg A.; Wang, Yak-Nam; Khokhlova, Vera A.; Crum, Lawrence A.; Bailey, Michael R.

2014-01-01

Ultrasonic atomization, or the emission of a fog of droplets, was recently proposed to explain tissue fractionation in boiling histotripsy. However, even though liquid atomization has been studied extensively, the mechanisms of tissue atomization remain unclear. In this paper, high-speed photography and overpressure were used to evaluate the role of bubbles in tissue atomization. As the static pressure increased, the degree of fractionation decreased, and the ex vivo tissue became thermally denatured. The effect of surface wetness on atomization was also evaluated in vivo and in tissue-mimicking gels where surface wetness was found to enhance atomization by forming surface instabilities that augment cavitation. In addition, experimental results indicated that wetting collagenous tissues, such as the liver capsule, allowed atomization to breach such barriers. These results highlight the importance of bubbles and surface instabilities in atomization and could be used to enhance boiling histotripsy for transition to clinical use. PMID:25662182

Effect of mutation at the interface of Trp-repressor dimeric protein: a steered molecular dynamics simulation.

PubMed

Miño, German; Baez, Mauricio; Gutierrez, Gonzalo

2013-09-01

The strength of key interfacial contacts that stabilize protein-protein interactions have been studied by computer simulation. Experimentally, changes in the interface are evaluated by generating specific mutations at one or more points of the protein structure. Here, such an evaluation is performed by means of steered molecular dynamics and use of a dimeric model of tryptophan repressor and in-silico mutants as a test case. Analysis of four particular cases shows that, in principle, it is possible to distinguish between wild-type and mutant forms by examination of the total energy and force-extension profiles. In particular, detailed atomic level structural analysis indicates that specific mutations at the interface of the dimeric model (positions 19 and 39) alter interactions that appear in the wild-type form of tryptophan repressor, reducing the energy and force required to separate both subunits.

A Self-Assessment Stereo Capture Model Applicable to the Internet of Things

PubMed Central

Lin, Yancong; Yang, Jiachen; Lv, Zhihan; Wei, Wei; Song, Houbing

2015-01-01

The realization of the Internet of Things greatly depends on the information communication among physical terminal devices and informationalized platforms, such as smart sensors, embedded systems and intelligent networks. Playing an important role in information acquisition, sensors for stereo capture have gained extensive attention in various fields. In this paper, we concentrate on promoting such sensors in an intelligent system with self-assessment capability to deal with the distortion and impairment in long-distance shooting applications. The core design is the establishment of the objective evaluation criteria that can reliably predict shooting quality with different camera configurations. Two types of stereo capture systems—toed-in camera configuration and parallel camera configuration—are taken into consideration respectively. The experimental results show that the proposed evaluation criteria can effectively predict the visual perception of stereo capture quality for long-distance shooting. PMID:26308004

Durability evaluation of ceramic components using CARES/LIFE

NASA Technical Reports Server (NTRS)

Nemeth, Noel N.; Powers, Lynn M.; Janosik, Lesley A.; Gyekenyesi, John P.

1994-01-01

The computer program CARES/LIFE calculates the time-dependent reliability of monolithic ceramic components subjected to thermomechanical and/or proof test loading. This program is an extension of the CARES (Ceramics Analysis and Reliability Evaluation of Structures) computer program. CARES/LIFE accounts for the phenomenon of subcritical crack growth (SCG) by utilizing the power law, Paris law, or Walker equation. The two-parameter Weibull cumulative distribution function is used to characterize the variation in component strength. The effects of multiaxial stresses are modeled using either the principle of independent action (PIA), the Weibull normal stress averaging method (NSA), or the Batdorf theory. Inert strength and fatigue parameters are estimated from rupture strength data of naturally flawed specimens loaded in static, dynamic, or cyclic fatigue. Application of this design methodology is demonstrated using experimental data from alumina bar and disk flexure specimens which exhibit SCG when exposed to water.

Durability evaluation of ceramic components using CARES/LIFE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nemeth, N.N.; Janosik, L.A.; Gyekenyesi, J.P.

1996-01-01

The computer program CARES/LIFE calculates the time-dependent reliability of monolithic ceramic components subjected to thermomechanical and/or proof test loading. This program is an extension of the CARES (Ceramics Analysis and Reliability Evaluation of Structures) computer program. CARES/LIFE accounts for the phenomenon of subcritical crack growth (SCG) by utilizing the power law, Paris law, or Walker equation. The two-parameter Weibull cumulative distribution function is used to characterize the variation in component strength. The effects of multiaxial stresses are modeled using either the principle of independent action (PIA), the Weibull normal stress averaging method (NSA), or the Batdorf theory. Inert strength andmore » fatigue parameters are estimated from rupture strength data of naturally flawed specimens loaded in static, dynamic, or cyclic fatigue. Application of this design methodology is demonstrated using experimental data from alumina bar and disk flexure specimens, which exhibit SCG when exposed to water.« less

Space Shuttle main engine product improvement

NASA Technical Reports Server (NTRS)

Lucci, A. D.; Klatt, F. P.

1985-01-01

The current design of the Space Shuttle Main Engine has passed 11 certification cycles, amassed approximately a quarter million seconds of engine test time in 1200 tests and successfully launched the Space Shuttle 17 times of 51 engine launches through May 1985. Building on this extensive background, two development programs are underway at Rocketdyne to improve the flow of hot gas through the powerhead and evaluate the changes to increase the performance margins in the engine. These two programs, called Phase II+ and Technology Test Bed Precursor program are described. Phase II+ develops a two-tube hot-gas manifold that improves the component environment. The Precursor program will evaluate a larger throat main combustion chamber, conduct combustion stability testing of a baffleless main injector, fabricate an experimental weld-free heat exchanger tube, fabricate and test a high pressure oxidizer turbopump with an improved inlet, and develop and test methods for reducing temperature transients at start and shutdown.

Proceedings of the Annual Conference of the Association for International Agricultural and Extension Education (15th, Port of Spain, Trinidad and Tobago March 21-26, 1999).

ERIC Educational Resources Information Center

Richardson, John G., Ed.

This proceedings contains session topics: extension systems, extension programs, extension evaluation, program impacts, extension management, extension reform, experiential learning, program delivery, farming systems research, professional training and development, program strategies, teaching effectiveness, organizational leadership, extension…

A Benchmark and Comparative Study of Video-Based Face Recognition on COX Face Database.

PubMed

Huang, Zhiwu; Shan, Shiguang; Wang, Ruiping; Zhang, Haihong; Lao, Shihong; Kuerban, Alifu; Chen, Xilin

2015-12-01

Face recognition with still face images has been widely studied, while the research on video-based face recognition is inadequate relatively, especially in terms of benchmark datasets and comparisons. Real-world video-based face recognition applications require techniques for three distinct scenarios: 1) Videoto-Still (V2S); 2) Still-to-Video (S2V); and 3) Video-to-Video (V2V), respectively, taking video or still image as query or target. To the best of our knowledge, few datasets and evaluation protocols have benchmarked for all the three scenarios. In order to facilitate the study of this specific topic, this paper contributes a benchmarking and comparative study based on a newly collected still/video face database, named COX(1) Face DB. Specifically, we make three contributions. First, we collect and release a largescale still/video face database to simulate video surveillance with three different video-based face recognition scenarios (i.e., V2S, S2V, and V2V). Second, for benchmarking the three scenarios designed on our database, we review and experimentally compare a number of existing set-based methods. Third, we further propose a novel Point-to-Set Correlation Learning (PSCL) method, and experimentally show that it can be used as a promising baseline method for V2S/S2V face recognition on COX Face DB. Extensive experimental results clearly demonstrate that video-based face recognition needs more efforts, and our COX Face DB is a good benchmark database for evaluation.

Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation.

PubMed

Sriskandan, Shiranee; Ferguson, Melissa; Elliot, Victoria; Faulkner, Lee; Cohen, Jonathan

2006-07-01

Polyclonal human intravenous immunoglobulin (IVIG) has been advocated as an adjunct to therapy in severe invasive streptococcal toxic shock because of its ability to neutralize superantigen toxins. The aim of this study was to assess IVIG therapeutic efficacy in an experimental model of streptococcal toxic shock. To confirm the in vitro activity of IVIG against the Streptococcus pyogenes strain used in the study, IVIG was tested for superantigen neutralizing and bacterial opsonizing activity prior to in vivo studies. To evaluate the in vivo effects of IVIG in terms of microbiological outcome and disease severity in a superantigen-sensitive transgenic model of streptococcal shock, HLA-DQ transgenic mice were treated with IVIG either at the time of infection or after infection with S. pyogenes. Antibiotics were included in some studies. The IVIG preparation neutralized superantigenicity of S. pyogenes in vitro and enhanced bacterial killing in a whole blood assay. When given to mice at the time of S. pyogenes infection, IVIG neutralized circulating superantigens and reduced systemic inflammatory response. Remarkably, IVIG-enhanced systemic clearance of bacteria and enhanced neutrophil infiltrate into the infected tissues. However, when used in combination with penicillin and clindamycin in a delayed treatment setting, IVIG did not confer additional therapeutic benefit, in terms of inflammatory response, bacterial clearance or survival. IVIG monotherapy can confer benefit in experimental streptococcal shock, but extension of these findings to the clinical situation will require further evaluation.

Unified constitutive models for high-temperature structural applications

NASA Technical Reports Server (NTRS)

Lindholm, U. S.; Chan, K. S.; Bodner, S. R.; Weber, R. M.; Walker, K. P.

1988-01-01

Unified constitutive models are characterized by the use of a single inelastic strain rate term for treating all aspects of inelastic deformation, including plasticity, creep, and stress relaxation under monotonic or cyclic loading. The structure of this class of constitutive theory pertinent for high temperature structural applications is first outlined and discussed. The effectiveness of the unified approach for representing high temperature deformation of Ni-base alloys is then evaluated by extensive comparison of experimental data and predictions of the Bodner-Partom and the Walker models. The use of the unified approach for hot section structural component analyses is demonstrated by applying the Walker model in finite element analyses of a benchmark notch problem and a turbine blade problem.

MOCC: A Fast and Robust Correlation-Based Method for Interest Point Matching under Large Scale Changes

NASA Astrophysics Data System (ADS)

Zhao, Feng; Huang, Qingming; Wang, Hao; Gao, Wen

2010-12-01

Similarity measures based on correlation have been used extensively for matching tasks. However, traditional correlation-based image matching methods are sensitive to rotation and scale changes. This paper presents a fast correlation-based method for matching two images with large rotation and significant scale changes. Multiscale oriented corner correlation (MOCC) is used to evaluate the degree of similarity between the feature points. The method is rotation invariant and capable of matching image pairs with scale changes up to a factor of 7. Moreover, MOCC is much faster in comparison with the state-of-the-art matching methods. Experimental results on real images show the robustness and effectiveness of the proposed method.

Persons Camp Using Interpolation Method

NASA Astrophysics Data System (ADS)

Tawfiq, Luma Naji Mohammed; Najm Abood, Israa

2018-05-01

The aim of this paper is to estimate the rate of contaminated soils by using suitable interpolation method as an alternative accurate tool to evaluate the concentration of heavy metals in soil then compared with standard universal value to determine the rate of contamination in the soil. In particular, interpolation methods are extensively applied in the models of the different phenomena where experimental data must be used in computer studies where expressions of those data are required. In this paper the extended divided difference method in two dimensions is used to solve suggested problem. Then, the modification method is applied to estimate the rate of contaminated soils of displaced persons camp in Diyala Governorate, in Iraq.

Flow and Dispersion in Urban Areas

NASA Astrophysics Data System (ADS)

Britter, R. E.

Increasing urbanization and concern about sustainability and quality of life issues have produced considerable interest in flow and dispersion in urban areas. We address this subject at four scales: regional, city, neighborhood, and street. The flow is one over and through a complex array of structures. Most of the local fluid mechanical processes are understood; how these combine and what is the most appropriate framework to study and quantify the result is less clear. Extensive and structured experimental databases have been compiled recently in several laboratories. A number of major field experiments in urban areas have been completed very recently and more are planned. These have aided understanding as well as model development and evaluation.

3D optic disc reconstruction via a global fundus stereo algorithm.

PubMed

Bansal, M; Sizintsev, M; Eledath, J; Sawhney, H; Pearson, D J; Stone, R A

2013-01-01

This paper presents a novel method to recover 3D structure of the optic disc in the retina from two uncalibrated fundus images. Retinal images are commonly uncalibrated when acquired clinically, creating rectification challenges as well as significant radiometric and blur differences within the stereo pair. By exploiting structural peculiarities of the retina, we modified the Graph Cuts computational stereo method (one of current state-of-the-art methods) to yield a high quality algorithm for fundus stereo reconstruction. Extensive qualitative and quantitative experimental evaluation (where OCT scans are used as 3D ground truth) on our and publicly available datasets shows the superiority of the proposed method in comparison to other alternatives.

Virtual Screening of Receptor Sites for Molecularly Imprinted Polymers.

PubMed

Bates, Ferdia; Cela-Pérez, María Concepción; Karim, Kal; Piletsky, Sergey; López-Vilariño, José Manuel

2016-08-01

Molecularly Imprinted Polymers (MIPs) are highly advantageous in the field of analytical chemistry. However, interference from secondary molecules can also impede capture of a target by a MIP receptor. This greatly complicates the design process and often requires extensive laboratory screening which is time consuming, costly, and creates substantial waste products. Herein, is presented a new technique for screening of "virtually imprinted receptors" for rebinding of the molecular template as well as secondary structures, correlating the virtual predictions with experimentally acquired data in three case studies. This novel technique is particularly applicable to the evaluation and prediction of MIP receptor specificity and efficiency in complex aqueous systems. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Perspectives on biotechnological applications of archaea

PubMed Central

Schiraldi, Chiara; Giuliano, Mariateresa; De Rosa, Mario

2002-01-01

Many archaea colonize extreme environments. They include hyperthermophiles, sulfur-metabolizing thermophiles, extreme halophiles and methanogens. Because extremophilic microorganisms have unusual properties, they are a potentially valuable resource in the development of novel biotechnological processes. Despite extensive research, however, there are few existing industrial applications of either archaeal biomass or archaeal enzymes. This review summarizes current knowledge about the biotechnological uses of archaea and archaeal enzymes with special attention to potential applications that are the subject of current experimental evaluation. Topics covered include cultivation methods, recent achievements in genomics, which are of key importance for the development of new biotechnological tools, and the application of wild-type biomasses, engineered microorganisms, enzymes and specific metabolites in particular bioprocesses of industrial interest. PMID:15803645

Perspectives on biotechnological applications of archaea.

PubMed

Schiraldi, Chiara; Giuliano, Mariateresa; De Rosa, Mario

2002-09-01

Many archaea colonize extreme environments. They include hyperthermophiles, sulfur-metabolizing thermophiles, extreme halophiles and methanogens. Because extremophilic microorganisms have unusual properties, they are a potentially valuable resource in the development of novel biotechnological processes. Despite extensive research, however, there are few existing industrial applications of either archaeal biomass or archaeal enzymes. This review summarizes current knowledge about the biotechnological uses of archaea and archaeal enzymes with special attention to potential applications that are the subject of current experimental evaluation. Topics covered include cultivation methods, recent achievements in genomics, which are of key importance for the development of new biotechnological tools, and the application of wild-type biomasses, engineered microorganisms, enzymes and specific metabolites in particular bioprocesses of industrial interest.

Failure Analysis of Discrete Damaged Tailored Extension-Shear-Coupled Stiffened Composite Panels

NASA Technical Reports Server (NTRS)

Baker, Donald J.

2005-01-01

The results of an analytical and experimental investigation of the failure of composite is tiffener panels with extension-shear coupling are presented. This tailored concept, when used in the cover skins of a tiltrotor aircraft wing has the potential for increasing the aeroelastic stability margins and improving the aircraft productivity. The extension-shear coupling is achieved by using unbalanced 45 plies in the skin. The failure analysis of two tailored panel configurations that have the center stringer and adjacent skin severed is presented. Finite element analysis of the damaged panels was conducted using STAGS (STructural Analysis of General Shells) general purpose finite element program that includes a progressive failure capability for laminated composite structures that is based on point-stress analysis, traditional failure criteria, and ply discounting for material degradation. The progressive failure predicted the path of the failure and maximum load capability. There is less than 12 percent difference between the predicted failure load and experimental failure load. There is a good match of the panel stiffness and strength between the progressive failure analysis and the experimental results. The results indicate that the tailored concept would be feasible to use in the wing skin of a tiltrotor aircraft.

Behavioral techniques for attenuating the expression of fear associations in an animal model of anxiety.

PubMed

Laborda, Mario A; Polack, Cody W; Miguez, Gonzalo; Miller, Ralph R

2014-09-01

Recent data indicate that extinguished fear often returns when the testing conditions differ from those of treatment. Several manipulations including extensive extinction training, extinction in multiple contexts, and spacing the extinction trials and sessions reduce the return of fear. Moreover, extensive extinction and extinction in multiple contexts summate in reducing return of fear, and the spacing of the extinction trials and the spacing of extinction sessions summate in reducing return of fear. Here we evaluated whether these techniques also attenuate the context specificity of latent inhibition, and whether they summate to further decrease fear responding at test. In two experiments, with rats as subjects in a lick suppression preparation, we assessed the effects of massive CS preexposure, CS preexposure in multiple contexts, and of spacing the CS-preexposure trials and sessions, in reducing the context specificity of latent inhibition. Fear responding was attenuated by all four manipulations. Moreover, extensive CS preexposure in multiple contexts, and conjoint spacing of the CS-preexposure trials and sessions, were more effective in reducing the context specificity of latent inhibition than each manipulation alone. Our experimental designs evaluated degrees of context specificity of latent inhibition but omitted groups in which latent inhibition was assessed without a context shift away from the context of latent inhibition treatment. This precluded us from drawing conclusions concerning absolute (as opposed to relative) levels of recovery from latent inhibition. Techniques effective in decreasing the return of conditioned fear following extinction are also effective in decreasing the context specificity of latent inhibition in an animal model of anxiety. Fear and anxiety disorders might be prevented in anxious human participants with the same techniques used here, but that is still an empirical question. Copyright © 2014 Elsevier Ltd. All rights reserved.

Physical human-robot interaction of an active pelvis orthosis: toward ergonomic assessment of wearable robots.

PubMed

d'Elia, Nicolò; Vanetti, Federica; Cempini, Marco; Pasquini, Guido; Parri, Andrea; Rabuffetti, Marco; Ferrarin, Maurizio; Molino Lova, Raffaele; Vitiello, Nicola

2017-04-14

In human-centered robotics, exoskeletons are becoming relevant for addressing needs in the healthcare and industrial domains. Owing to their close interaction with the user, the safety and ergonomics of these systems are critical design features that require systematic evaluation methodologies. Proper transfer of mechanical power requires optimal tuning of the kinematic coupling between the robotic and anatomical joint rotation axes. We present the methods and results of an experimental evaluation of the physical interaction with an active pelvis orthosis (APO). This device was designed to effectively assist in hip flexion-extension during locomotion with a minimum impact on the physiological human kinematics, owing to a set of passive degrees of freedom for self-alignment of the human and robotic hip flexion-extension axes. Five healthy volunteers walked on a treadmill at different speeds without and with the APO under different levels of assistance. The user-APO physical interaction was evaluated in terms of: (i) the deviation of human lower-limb joint kinematics when wearing the APO with respect to the physiological behavior (i.e., without the APO); (ii) relative displacements between the APO orthotic shells and the corresponding body segments; and (iii) the discrepancy between the kinematics of the APO and the wearer's hip joints. The results show: (i) negligible interference of the APO in human kinematics under all the experimented conditions; (ii) small (i.e., < 1 cm) relative displacements between the APO cuffs and the corresponding body segments (called stability); and (iii) significant increment in the human-robot kinematics discrepancy at the hip flexion-extension joint associated with speed and assistance level increase. APO mechanics and actuation have negligible interference in human locomotion. Human kinematics was not affected by the APO under all tested conditions. In addition, under all tested conditions, there was no relevant relative displacement between the orthotic cuffs and the corresponding anatomical segments. Hence, the physical human-robot coupling is reliable. These facts prove that the adopted mechanical design of passive degrees of freedom allows an effective human-robot kinematic coupling. We believe that this analysis may be useful for the definition of evaluation metrics for the ergonomics assessment of wearable robots.

The Effectiveness of Asulam for Bracken ( Pteridium aquilinum) Control in the United Kingdom: A Meta-Analysis

NASA Astrophysics Data System (ADS)

Stewart, Gavin B.; Pullin, Andrew S.; Tyler, Claire

2007-11-01

Bracken ( Pteridium aquilinum) is a major problem for livestock-based extensive agriculture, conservation, recreation, and game management globally. It is an invasive species often achieving dominance to the detriment of other species. Control is essential to maintain plant communities such as grassland and lowland heath or if extensive grazing by domestic stock, particularly sheep, is to be viable on upland margins. Bracken is managed primarily by herbicide application or cutting but other techniques including rolling, burning, and grazing are also utilized. Here we evaluate the evidence regarding the effectiveness of asulam for the control of bracken. Thirteen studies provided data for meta-analyses which demonstrate that application of the herbicide asulam reduces bracken abundance. Subgroup analyses indicate that the number of treatments had an important impact, with multiple follow-up treatments more effective than one or two treatments. Management practices should reflect the requirement for repeated follow-up. There is insufficient available experimental evidence for quantitative analysis of the effectiveness of other management interventions, although this results from lack of reporting in papers where cutting and comparisons of cutting and asulam application are concerned. Systematic searching and meta-analytical synthesis have effectively demonstrated the limits of current knowledge, based on recorded empirical evidence, and increasing the call for more rigorous monitoring of bracken control techniques. Lack of experimental evidence on the effectiveness of management such as rolling or grazing with hardy cattle breeds contrasts with the widespread acceptance of their use through dissemination of experience.

Pure moment testing for spinal biomechanics applications: Fixed versus sliding ring cable-driven test designs.

PubMed

Eguizabal, Johnny; Tufaga, Michael; Scheer, Justin K; Ames, Christopher; Lotz, Jeffrey C; Buckley, Jenni M

2010-05-07

In vitro multi-axial bending testing using pure moment loading conditions has become the standard in evaluating the effects of different types of surgical intervention on spinal kinematics. Simple, cable-driven experimental set-ups have been widely adopted because they require little infrastructure. Traditionally, "fixed ring" cable-driven experimental designs have been used; however, there have been concerns with the validity of this set-up in applying pure moment loading. This study involved directly comparing the loading state induced by a traditional "fixed ring" apparatus versus a novel "sliding ring" approach. Flexion-extension bending was performed on an artificial spine model and a single cadaveric test specimen, and the applied loading conditions to the specimen were measured with an in-line multiaxial load cell. The results showed that the fixed ring system applies flexion-extension moments that are 50-60% less than the intended values. This design also imposes non-trivial anterior-posterior shear forces, and non-uniform loading conditions were induced along the length of the specimen. The results of this study indicate that fixed ring systems have the potential to deviate from a pure moment loading state and that our novel sliding ring modification corrects this error in the original test design. This suggests that the proposed sliding ring design should be used for future in vitro spine biomechanics studies involving a cable-driven pure moment apparatus. Copyright 2010 Elsevier Ltd. All rights reserved.

Viral infection--a cure for type 1 diabetes?

PubMed

Hintermann, Edith; Christen, Urs

2007-01-01

Autoimmune diseases are thought to arise as a detrimental combination of genetic predisposition and environmental factors. Because of their potential for direct cellular damage and causing extensive inflammation, viruses are one of the major candidates for triggering autoimmunity. Although there is epidemiological evidence, direct proof for viruses as causative agents for autoimmune disease is hard to get since most viruses have been eliminated from the system by the time of diagnosis. However, evidence from various animal models suggests that viruses can indeed initiate or accelerate autoimmune diseases, such as type 1 diabetes or experimental allergic encephalomyelitis. In contrast, viruses have been also demonstrated to abrogate autoimmune disease in animal models. These observations might offer one explanation why increased frequencies of allergies and autoimmune diseases parallel with higher hygienic standards. This review reflects on the epidemiological evidence for the association of viruses with autoimmune diseases, the experimental evidence for viruses to abrogate an ongoing autoimmune destruction and evaluates the possibility for a therapeutic application.

Aniracetam reverses memory impairment in rats.

PubMed

Martin, J R; Moreau, J L; Jenck, F

1995-02-01

The pyrrolidinone derivative aniracetam given orally immediately after acquisition of an inhibitory avoidance response reproducibly ameliorated scopolamine-induced amnesia in female rats in an extensive series of test sessions conducted over a 1-year period. In a dose-response experiment it was demonstrated that 50 mg kg-1 was the lowest oral dose of aniracetam to significantly ameliorate scopolamine-induced amnesia. Combined results from these numerous test sessions demonstrated that 50 mg kg-1 aniracetam administered to scopolamine-treated rats resulted in 53% of the animals exhibiting correct passive avoidance responding in the retention evaluation versus 9% of the scopolamine-treated rats given vehicle (in comparison, 64% of the rats injected with vehicle rather than scopolamine in this experimental situation exhibited correct responding in the retention test). There was minimal variation in this pattern of results over the successive 1-month blocks constituting the complete experimental period. Thus, the nootropic compound aniracetam replicably exhibited memory enhancing effects in this animal model of reduced cholinergic function.

Robust and Efficient Biomolecular Clustering of Tumor Based on ${p}$ -Norm Singular Value Decomposition.

PubMed

Kong, Xiang-Zhen; Liu, Jin-Xing; Zheng, Chun-Hou; Hou, Mi-Xiao; Wang, Juan

2017-07-01

High dimensionality has become a typical feature of biomolecular data. In this paper, a novel dimension reduction method named p-norm singular value decomposition (PSVD) is proposed to seek the low-rank approximation matrix to the biomolecular data. To enhance the robustness to outliers, the Lp-norm is taken as the error function and the Schatten p-norm is used as the regularization function in the optimization model. To evaluate the performance of PSVD, the Kmeans clustering method is then employed for tumor clustering based on the low-rank approximation matrix. Extensive experiments are carried out on five gene expression data sets including two benchmark data sets and three higher dimensional data sets from the cancer genome atlas. The experimental results demonstrate that the PSVD-based method outperforms many existing methods. Especially, it is experimentally proved that the proposed method is more efficient for processing higher dimensional data with good robustness, stability, and superior time performance.

Experimental test program for evaluation of solid lubricant coating as applied to compliant foil gas bearings to 315 deg C

NASA Technical Reports Server (NTRS)

Wagner, R. C.

1985-01-01

An experimental apparatus and test procedure was developed to compare the performance of two solid lubricant coatings for air lubricated compliant foil gas bearings in the temperature range of 25 to 315 C. Polyimide bonded additive (SBGC) were tested extensively for durability and frictional characteristics. A partial arc bearing constructed of Inconel X-750 was coated on the bore with one of these coatings. The foil was subjected to repeated start/stop cycles. Performance comparisons reveal that although both coatings survive thousands of start/stop cycles, only the PBGF coated bearing achieves the specified 9000 start/stops. There is enough wear on the SBGC coated bearing to warrant termination of the test prior to 9000 start/stop cycles due to coating failure. The frictional characteristics of the PBGF are better at the elevated temperatures than at lower temperatures; a marked increase in sliding friction occurs as the temperature decreases. The SBGC maintains relatively constant frictional characteristics independent of operating temperature.

Modelling and experimental evaluation of parallel connected lithium ion cells for an electric vehicle battery system

NASA Astrophysics Data System (ADS)

Bruen, Thomas; Marco, James

2016-04-01

Variations in cell properties are unavoidable and can be caused by manufacturing tolerances and usage conditions. As a result of this, cells connected in series may have different voltages and states of charge that limit the energy and power capability of the complete battery pack. Methods of removing this energy imbalance have been extensively reported within literature. However, there has been little discussion around the effect that such variation has when cells are connected electrically in parallel. This work aims to explore the impact of connecting cells, with varied properties, in parallel and the issues regarding energy imbalance and battery management that may arise. This has been achieved through analysing experimental data and a validated model. The main results from this study highlight that significant differences in current flow can occur between cells within a parallel stack that will affect how the cells age and the temperature distribution within the battery assembly.

Study of combustion experiments in space

NASA Technical Reports Server (NTRS)

Berlad, A. L.; Huggett, C.; Kaufman, F.; Markstein, G. H.; Palmer, H. B.; Yang, C. H.

1974-01-01

The physical bases and scientific merits were examined of combustion experimentation in a space environment. For a very broad range of fundamental combustion problems, extensive and systematic experimentation at reduced gravitational levels (0 g 1) are viewed as essential to the development of needed observations and related theoretical understanding.

Using Experimental Methods in Higher Education Research

ERIC Educational Resources Information Center

Ross, Steven M.; Morrison, Gary R.; Lowther, Deborah L.

2005-01-01

Experimental methods have been used extensively for many years to conduct research in education and psychology. However, applications of experiments to investigate technology and other instructional innovations in higher education settings have been relatively limited. The present paper examines ways in which experiments can be used productively…

Why Does Experimentation Matter in Teaching Ecology?

ERIC Educational Resources Information Center

Finn, Hugh; Maxwell, Marika; Calver, Michael

2002-01-01

Suggests that because controlled experiments are used extensively by professional ecologists to solve both theoretical and applied problems, experimentation should be a key component of secondary school ecology curricula. Describes five teaching principles to guide secondary school biology teachers in providing a more realistic view of the…

Nonlinear Elasticity of Doped Semiconductors

DTIC Science & Technology

2017-02-01

experimental data from the Stanford University group. The obtained results show that the goal of the project has been reached. MSU has full...length extension modes in n-doped silicon (Si) microelectromechanical (MEMS) resonators and have started a comparison with the experimental data from...coupling to shear strain modes. • Tested the theory against the existing in the literature experimental data on the effect of doping on the speed of

Imaging of neural oscillations with embedded inferential and group prevalence statistics.

PubMed

Donhauser, Peter W; Florin, Esther; Baillet, Sylvain

2018-02-01

Magnetoencephalography and electroencephalography (MEG, EEG) are essential techniques for studying distributed signal dynamics in the human brain. In particular, the functional role of neural oscillations remains to be clarified. For that reason, imaging methods need to identify distinct brain regions that concurrently generate oscillatory activity, with adequate separation in space and time. Yet, spatial smearing and inhomogeneous signal-to-noise are challenging factors to source reconstruction from external sensor data. The detection of weak sources in the presence of stronger regional activity nearby is a typical complication of MEG/EEG source imaging. We propose a novel, hypothesis-driven source reconstruction approach to address these methodological challenges. The imaging with embedded statistics (iES) method is a subspace scanning technique that constrains the mapping problem to the actual experimental design. A major benefit is that, regardless of signal strength, the contributions from all oscillatory sources, which activity is consistent with the tested hypothesis, are equalized in the statistical maps produced. We present extensive evaluations of iES on group MEG data, for mapping 1) induced oscillations using experimental contrasts, 2) ongoing narrow-band oscillations in the resting-state, 3) co-modulation of brain-wide oscillatory power with a seed region, and 4) co-modulation of oscillatory power with peripheral signals (pupil dilation). Along the way, we demonstrate several advantages of iES over standard source imaging approaches. These include the detection of oscillatory coupling without rejection of zero-phase coupling, and detection of ongoing oscillations in deeper brain regions, where signal-to-noise conditions are unfavorable. We also show that iES provides a separate evaluation of oscillatory synchronization and desynchronization in experimental contrasts, which has important statistical advantages. The flexibility of iES allows it to be adjusted to many experimental questions in systems neuroscience.

Experimental and numerical investigation into the influence of loading conditions in biomechanical testing of locking plate fracture fixation devices

PubMed Central

MacLeod, A.; Simpson, A. H. R. W.

2018-01-01

Objectives Secondary fracture healing is strongly influenced by the stiffness of the bone-fixator system. Biomechanical tests are extensively used to investigate stiffness and strength of fixation devices. The stiffness values reported in the literature for locked plating, however, vary by three orders of magnitude. The aim of this study was to examine the influence that the method of restraint and load application has on the stiffness produced, the strain distribution within the bone, and the stresses in the implant for locking plate constructs. Methods Synthetic composite bones were used to evaluate experimentally the influence of four different methods of loading and restraining specimens, all used in recent previous studies. Two plate types and three screw arrangements were also evaluated for each loading scenario. Computational models were also developed and validated using the experimental tests. Results The method of loading was found to affect the gap stiffness strongly (by up to six times) but also the magnitude of the plate stress and the location and magnitude of strains at the bone-screw interface. Conclusions This study demonstrates that the method of loading is responsible for much of the difference in reported stiffness values in the literature. It also shows that previous contradictory findings, such as the influence of working length and very large differences in failure loads, can be readily explained by the choice of loading condition. Cite this article: A. MacLeod, A. H. R. W. Simpson, P. Pankaj. Experimental and numerical investigation into the influence of loading conditions in biomechanical testing of locking plate fracture fixation devices. Bone Joint Res 2018;7:111–120. DOI: 10.1302/2046-3758.71.BJR-2017-0074.R2. PMID:29363522

Electromyography function, disability degree, and pain in leprosy patients undergoing neural mobilization treatment.

PubMed

Véras, Larissa Sales Téles; Vale, Rodrigo Gomes de Souza; Mello, Danielli Braga de; Castro, José Adail Fonseca de; Lima, Vicente; Trott, Alexis; Dantas, Estélio Henrique Martin

2012-02-01

This study aimed to evaluate the effect of the neural mobilization technique on electromyography function, disability degree, and pain in patients with leprosy. A sample of 56 individuals with leprosy was randomized into an experimental group, composed of 29 individuals undergoing treatment with neural mobilization, and a control group of 27 individuals who underwent conventional treatment. In both groups, the lesions in the lower limbs were treated. In the treatment with neural mobilization, the procedure used was mobilization of the lumbosacral roots and sciatic nerve biased to the peroneal nerve that innervates the anterior tibial muscle, which was evaluated in the electromyography. Analysis of the electromyography function showed a significant increase (p<0.05) in the experimental group in both the right (Δ%=22.1, p=0.013) and the left anterior tibial muscles (Δ%=27.7, p=0.009), compared with the control group pre- and post-test. Analysis of the strength both in the movement of horizontal extension (Δ%right=11.7, p=0.003/Δ%left=27.4, p=0.002) and in the movement of back flexion (Δ%right=31.1; p=0.000/Δ%left=34.7, p=0.000) showed a significant increase (p<0.05) in both the right and the left segments when comparing the experimental group pre- and post-test. The experimental group showed a significant reduction (p=0.000) in pain perception and disability degree when the pre- and post-test were compared and when compared with the control group in the post-test. Leprosy patients undergoing the technique of neural mobilization had an improvement in electromyography function and muscle strength, reducing disability degree and pain.

Imaging of neural oscillations with embedded inferential and group prevalence statistics

PubMed Central

2018-01-01

Magnetoencephalography and electroencephalography (MEG, EEG) are essential techniques for studying distributed signal dynamics in the human brain. In particular, the functional role of neural oscillations remains to be clarified. For that reason, imaging methods need to identify distinct brain regions that concurrently generate oscillatory activity, with adequate separation in space and time. Yet, spatial smearing and inhomogeneous signal-to-noise are challenging factors to source reconstruction from external sensor data. The detection of weak sources in the presence of stronger regional activity nearby is a typical complication of MEG/EEG source imaging. We propose a novel, hypothesis-driven source reconstruction approach to address these methodological challenges. The imaging with embedded statistics (iES) method is a subspace scanning technique that constrains the mapping problem to the actual experimental design. A major benefit is that, regardless of signal strength, the contributions from all oscillatory sources, which activity is consistent with the tested hypothesis, are equalized in the statistical maps produced. We present extensive evaluations of iES on group MEG data, for mapping 1) induced oscillations using experimental contrasts, 2) ongoing narrow-band oscillations in the resting-state, 3) co-modulation of brain-wide oscillatory power with a seed region, and 4) co-modulation of oscillatory power with peripheral signals (pupil dilation). Along the way, we demonstrate several advantages of iES over standard source imaging approaches. These include the detection of oscillatory coupling without rejection of zero-phase coupling, and detection of ongoing oscillations in deeper brain regions, where signal-to-noise conditions are unfavorable. We also show that iES provides a separate evaluation of oscillatory synchronization and desynchronization in experimental contrasts, which has important statistical advantages. The flexibility of iES allows it to be adjusted to many experimental questions in systems neuroscience. PMID:29408902

Improved design and durability of aluminum die casting horizontal shot sleeves

NASA Astrophysics Data System (ADS)

Birceanu, Sebastian

The design and performance of shot sleeves is critical in meeting the engineering requirements of aluminum die cast parts. Improvement in shot sleeve materials have a major impact on dimensional stability, reproducibility and quality of the product. This investigation was undertaken in order to improve the life of aluminum die casting horizontal shot sleeves. Preliminary pin tests were run to evaluate the soldering, wash-out and thermal fatigue behavior of commercially available materials and coatings. An experimental rig was designed and constructed for shot sleeve configuration evaluation. Fabrication and testing of experimental shot sleeves was based upon preliminary results and manufacturing costs. Three shot sleeve designs and materials were compared to a reference nitrided H13 sleeve. Nitrided H13 is the preferred material for aluminum die casting shot sleeves because of wear resistance, strength and relative good soldering and wash-out resistance. The study was directed towards damage evaluation on the area under the pouring hole. This area is the most susceptible to damage because of high temperatures and impingement of molten aluminum. The results of this study showed that tungsten and molybdenum had the least amount of soldering and wash-out damage, and the best thermal fatigue resistance. Low solubility in molten aluminum and stability of intermetallic layers are main factors that determine the soldering and wash-out behavior. Thermal conductivity and thermal expansion coefficient directly influence thermal fatigue behavior. TiAlN nanolayered coating was chosen as the material with the best damage resistance among several commercial PVD coatings, because of relatively large thickness and simple deposition conditions. The results show that molybdenum thermal sprayed coating provided the best protection against damage under the pouring hole. Improved bonding is however required for life extension of the coating. TiAlN PVD coating applied on H13 nitrided substrate performed very well as long as the coating was maintained. Nitrided H13 sleeve showed extensive damage that occurred as early as 200 cycles. The nitrided layer only slowed down the diffusion process and dissolution took place at a higher rate as soon as the layer wore off. Stellite 6 sleeve also showed considerable wear under the action of molten aluminum.

A decision support model for investment on P2P lending platform.

PubMed

Zeng, Xiangxiang; Liu, Li; Leung, Stephen; Du, Jiangze; Wang, Xun; Li, Tao

2017-01-01

Peer-to-peer (P2P) lending, as a novel economic lending model, has triggered new challenges on making effective investment decisions. In a P2P lending platform, one lender can invest N loans and a loan may be accepted by M investors, thus forming a bipartite graph. Basing on the bipartite graph model, we built an iteration computation model to evaluate the unknown loans. To validate the proposed model, we perform extensive experiments on real-world data from the largest American P2P lending marketplace-Prosper. By comparing our experimental results with those obtained by Bayes and Logistic Regression, we show that our computation model can help borrowers select good loans and help lenders make good investment decisions. Experimental results also show that the Logistic classification model is a good complement to our iterative computation model, which motivates us to integrate the two classification models. The experimental results of the hybrid classification model demonstrate that the logistic classification model and our iteration computation model are complementary to each other. We conclude that the hybrid model (i.e., the integration of iterative computation model and Logistic classification model) is more efficient and stable than the individual model alone.

A combined experimental and finite element study to predict the failure mechanisms in SiC coated carbon/carbon composites at room and elevated temperatures under flexural loading

NASA Technical Reports Server (NTRS)

Mahfuz, Hassan; Das, Partha S.; Xue, Dongwei; Krishnagopalan, Jaya; Jeelani, Shaik

1993-01-01

Response of quasi-isotropic laminates of SiC coated Carbon/Carbon (C/C) composites have been investigated under flexural loading at various temperatures. Variation of load-deflection behavior with temperatures are studied. Increase in flexural strength and stiffness are observed with the rise in temperature. Extensive analyses through Optical Microscope (OM) and Non-Destructive Evaluation (NDE) have been performed to understand the failure mechanisms. Damage zone is found only within the neighborhood of the loading plane. Isoparametric layered shell elements developed on the basis of the first order shear deformation theory have been used to model the thin laminates of C/C under flexural loading. Large deformation behavior has been considered in the finite element analysis to account for the non-linearities encountered during the actual test. Data generated using finite element analysis are presented to corroborate the experimental findings, and a comparison in respect of displacement and stress-strain behavior are given to check the accuracy of the finite element analysis. Reasonable correlation between the experimental and finite element results have been established.

Understanding the oriented-attachment growth of nanocrystals from an energy point of view: a review

NASA Astrophysics Data System (ADS)

Lv, Weiqiang; He, Weidong; Wang, Xiaoning; Niu, Yinghua; Cao, Huanqi; Dickerson, James H.; Wang, Zhiguo

2014-02-01

Since Penn et al. first discovered the oriented attachment growth of crystals, the oriented attachment mechanism has now become a major research focus in the crystal field, and extensive efforts have been carried out over the past decade to systematically investigate the growth mechanism and the statistical kinetic models. However, most of the work mainly focuses on the experimental results on the oriented attachment growth. In contrast to the previous reviews, our review provides an overview of the recent theoretical advances in oriented attachment kinetics combined with experimental evidences. After a brief introduction to the van der Waals interaction and Coulombic interaction in a colloidal system, the correlation between the kinetic models of oriented attachment growth and the interactions is then our focus. The impact of in situ experimental observation techniques on the study of oriented attachment growth is examined with insightful examples. In addition, the advances in theoretical simulations mainly investigating the thermodynamic origin of these interactions at the atomic level are reviewed. This review seeks to understand the oriented attachment crystal growth from a kinetic point of view and provide a quantitative methodology to rationally design an oriented attachment system with pre-evaluated crystal growth parameters.

A decision support model for investment on P2P lending platform

PubMed Central

Liu, Li; Leung, Stephen; Du, Jiangze; Wang, Xun; Li, Tao

2017-01-01

Peer-to-peer (P2P) lending, as a novel economic lending model, has triggered new challenges on making effective investment decisions. In a P2P lending platform, one lender can invest N loans and a loan may be accepted by M investors, thus forming a bipartite graph. Basing on the bipartite graph model, we built an iteration computation model to evaluate the unknown loans. To validate the proposed model, we perform extensive experiments on real-world data from the largest American P2P lending marketplace—Prosper. By comparing our experimental results with those obtained by Bayes and Logistic Regression, we show that our computation model can help borrowers select good loans and help lenders make good investment decisions. Experimental results also show that the Logistic classification model is a good complement to our iterative computation model, which motivates us to integrate the two classification models. The experimental results of the hybrid classification model demonstrate that the logistic classification model and our iteration computation model are complementary to each other. We conclude that the hybrid model (i.e., the integration of iterative computation model and Logistic classification model) is more efficient and stable than the individual model alone. PMID:28877234

Improvement of mechanical properties and life extension of high reliability structural components by laser shock processing

NASA Astrophysics Data System (ADS)

Ocaña, J. L.; Morales, M.; Porro, J. A.; Iordachescu, D.; Díaz, M.; Ruiz de Lara, L.; Correa, C.

2011-05-01

Profiting by the increasing availability of laser sources delivering intensities above 109 W/cm2 with pulse energies in the range of several Joules and pulse widths in the range of nanoseconds, laser shock processing (LSP) is being consolidating as an effective technology for the improvement of surface mechanical and corrosion resistance properties of metals and is being developed as a practical process amenable to production engineering. The main acknowledged advantage of the laser shock processing technique consists on its capability of inducing a relatively deep compression residual stresses field into metallic alloy pieces allowing an improved mechanical behaviour, explicitly, the life improvement of the treated specimens against wear, crack growth and stress corrosion cracking. Following a short description of the theoretical/computational and experimental methods developed by the authors for the predictive assessment and experimental implementation of LSP treatments, experimental results on the residual stress profiles and associated surface properties modification successfully reached in typical materials (specifically Al and Ti alloys) under different LSP irradiation conditions are presented. In particular, the analysis of the residual stress profiles obtained under different irradiation parameters and the evaluation of the corresponding induced surface properties as roughness and wear resistance are presented.

Baseline experimental investigation of an electrohydrodynamically assisted heat pipe

NASA Technical Reports Server (NTRS)

Duncan, A. B.

1995-01-01

The increases in power demand and associated thermal management requirements of future space programs such as potential Lunar/Mars missions will require enhancing the operating efficiencies of thermal management devices. Currently, the use of electrohydrodynamically (EHD) assisted thermal control devices is under consideration as a potential method of increasing thermal management system capacity. The objectives of the currently described investigation included completing build-up of the EHD-Assisted Heat Pipe Test bed, developing test procedures for an experimental evaluation of the unassisted heat pipe, developing an analytical model capable of predicting the performance limits of the unassisted heat pipe, and obtaining experimental data which would define the performance characteristics of the unassisted heat pipe. The information obtained in the currently proposed study will be used in order to provide extensive comparisons with the EHD-assisted performance observations to be obtained during the continuing investigation of EHD-Assisted heat transfer devices. Through comparisons of the baseline test bed data and the EHD assisted test bed data, accurate insight into the performance enhancing characteristics of EHD augmentation may be obtained. This may lead to optimization, development, and implementation of EHD technology for future space programs.

Light-weight extension tubes for compressed-air garden sprayers

Treesearch

Thomas W. McConkey; Charles E. Swett

1967-01-01

To hand-spray taller trees safely and efficiently, 8-, 12-, and 16-foot extension tubes for compressed-air garden sprayers were designed and built. These light-weight tubes have been used successfully for spraying white pine leaders for weevil control on the Massabesic Experimental Forest in Maine. Bill of materials and assembly instructions are included.

Productive Extension of Semantic Memory in School-Aged Children: Relations with Reading Comprehension and Deployment of Cognitive Resources

ERIC Educational Resources Information Center

Bauer, Patricia J.; Blue, Shala N.; Xu, Aoxiang; Esposito, Alena G.

2016-01-01

We investigated 7- to 10-year-old children's productive extension of semantic memory through self-generation of new factual knowledge derived through integration of separate yet related facts learned through instruction or through reading. In Experiment 1, an experimenter read the to-be-integrated facts. Children successfully learned and…

Is the Treatment with Biological or Non-biological DMARDS a Modifier of Periodontal Condition in Patients with Rheumatoid Arthritis?

PubMed

Romero-Sanchez, Consuelo; Rodríguez, C; Santos-Moreno, P; Mesa, A M; Lafaurie, G I; Giraldo-Q, S; De-Avila, J; Castillo, D M; Duran, M; Chalem, P Ch; Bello Gualtero, J M; Valle-Oñate, R

2017-01-01

Experimental models suggest the use of different therapy protocols in rheumatoid arthritis (RA) as modulators on periodontal condition. This study evaluated the effects of conventional drug treatment and anti-TNF therapy in patients with RA on microbiological and periodontal condition, establishing the association of markers of periodontal infection with indexes of rheumatic activity. One hundred seventy nine individuals with RA were evaluated (62 with anti-TNF-. and 115 with only DMARDs). The periodontal evaluation included plaque and gingival indexes, bleeding on probing (BOP), clinical attachment loss (CAL), pocket depth (PD) and subgingival plaque samples for microbiological analysis. Rheumatologic evaluations included a clinical examination, rheumatoid factor (RF), antibodies against cyclic-citrullinated peptides (ACPAs), and activity markers (DAS28-ERS), high sensitive C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR). Anti-TNF-alpha therapy influenced periodontal microbiota with a higher frequency of T. denticola (p=0.01). Methotrexate combined with leflunomide exhibited a higher extension of CAL (p=0.005), and anti-TNF-alpha therapy with methotrexate was associated with a lower extension of CAL (p=0.05). The use of corticosteroids exerted a protective effect on the number of teeth (p=0.027). The type of DMARD affected P. gingivalis, T. forsythia and E. nodatum presence. Elevated ACPAs titers were associated with the presence of red complex periodontal pathogens (p=0.025). Bleeding on probing was associated with elevated CPR levels (p=0.05), and ESR was associated with a greater PD (p=0.044) and presence of red complex (p=0.030). Different pharmacological treatments for RA affect the clinical condition and subgingival microbiota. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Experimental Errors in QSAR Modeling Sets: What We Can Do and What We Cannot Do.

PubMed

Zhao, Linlin; Wang, Wenyi; Sedykh, Alexander; Zhu, Hao

2017-06-30

Numerous chemical data sets have become available for quantitative structure-activity relationship (QSAR) modeling studies. However, the quality of different data sources may be different based on the nature of experimental protocols. Therefore, potential experimental errors in the modeling sets may lead to the development of poor QSAR models and further affect the predictions of new compounds. In this study, we explored the relationship between the ratio of questionable data in the modeling sets, which was obtained by simulating experimental errors, and the QSAR modeling performance. To this end, we used eight data sets (four continuous endpoints and four categorical endpoints) that have been extensively curated both in-house and by our collaborators to create over 1800 various QSAR models. Each data set was duplicated to create several new modeling sets with different ratios of simulated experimental errors (i.e., randomizing the activities of part of the compounds) in the modeling process. A fivefold cross-validation process was used to evaluate the modeling performance, which deteriorates when the ratio of experimental errors increases. All of the resulting models were also used to predict external sets of new compounds, which were excluded at the beginning of the modeling process. The modeling results showed that the compounds with relatively large prediction errors in cross-validation processes are likely to be those with simulated experimental errors. However, after removing a certain number of compounds with large prediction errors in the cross-validation process, the external predictions of new compounds did not show improvement. Our conclusion is that the QSAR predictions, especially consensus predictions, can identify compounds with potential experimental errors. But removing those compounds by the cross-validation procedure is not a reasonable means to improve model predictivity due to overfitting.

Experimental Errors in QSAR Modeling Sets: What We Can Do and What We Cannot Do

PubMed Central

2017-01-01

Numerous chemical data sets have become available for quantitative structure–activity relationship (QSAR) modeling studies. However, the quality of different data sources may be different based on the nature of experimental protocols. Therefore, potential experimental errors in the modeling sets may lead to the development of poor QSAR models and further affect the predictions of new compounds. In this study, we explored the relationship between the ratio of questionable data in the modeling sets, which was obtained by simulating experimental errors, and the QSAR modeling performance. To this end, we used eight data sets (four continuous endpoints and four categorical endpoints) that have been extensively curated both in-house and by our collaborators to create over 1800 various QSAR models. Each data set was duplicated to create several new modeling sets with different ratios of simulated experimental errors (i.e., randomizing the activities of part of the compounds) in the modeling process. A fivefold cross-validation process was used to evaluate the modeling performance, which deteriorates when the ratio of experimental errors increases. All of the resulting models were also used to predict external sets of new compounds, which were excluded at the beginning of the modeling process. The modeling results showed that the compounds with relatively large prediction errors in cross-validation processes are likely to be those with simulated experimental errors. However, after removing a certain number of compounds with large prediction errors in the cross-validation process, the external predictions of new compounds did not show improvement. Our conclusion is that the QSAR predictions, especially consensus predictions, can identify compounds with potential experimental errors. But removing those compounds by the cross-validation procedure is not a reasonable means to improve model predictivity due to overfitting. PMID:28691113

The role of technetium-99m stannous pyrophosphate in myocardial imaging to recognize, localize and identify extension of acute myocardial infarction in patients

NASA Technical Reports Server (NTRS)

Willerson, J. T.; Parkey, R. W.; Bonte, F. J.; Stokely, E. M.; Buja, E. M.

1975-01-01

The ability of technetium-99m stannous pyrophosphate myocardial scintigrams to aid diagnostically in recognizing, localizing, and identifying extension of acute myocardial infarction in patients was evaluated. The present study is an extension of previous animal and patient evaluations that were recently performed utilizing this myocardial imaging agent.

Real-Time Robust Tracking for Motion Blur and Fast Motion via Correlation Filters

PubMed Central

Xu, Lingyun; Luo, Haibo; Hui, Bin; Chang, Zheng

2016-01-01

Visual tracking has extensive applications in intelligent monitoring and guidance systems. Among state-of-the-art tracking algorithms, Correlation Filter methods perform favorably in robustness, accuracy and speed. However, it also has shortcomings when dealing with pervasive target scale variation, motion blur and fast motion. In this paper we proposed a new real-time robust scheme based on Kernelized Correlation Filter (KCF) to significantly improve performance on motion blur and fast motion. By fusing KCF and STC trackers, our algorithm also solve the estimation of scale variation in many scenarios. We theoretically analyze the problem for CFs towards motions and utilize the point sharpness function of the target patch to evaluate the motion state of target. Then we set up an efficient scheme to handle the motion and scale variation without much time consuming. Our algorithm preserves the properties of KCF besides the ability to handle special scenarios. In the end extensive experimental results on benchmark of VOT datasets show our algorithm performs advantageously competed with the top-rank trackers. PMID:27618046

Standardization in synthetic biology: an engineering discipline coming of age.

PubMed

Decoene, Thomas; De Paepe, Brecht; Maertens, Jo; Coussement, Pieter; Peters, Gert; De Maeseneire, Sofie L; De Mey, Marjan

2018-08-01

Leaping DNA read-and-write technologies, and extensive automation and miniaturization are radically transforming the field of biological experimentation by providing the tools that enable the cost-effective high-throughput required to address the enormous complexity of biological systems. However, standardization of the synthetic biology workflow has not kept abreast with dwindling technical and resource constraints, leading, for example, to the collection of multi-level and multi-omics large data sets that end up disconnected or remain under- or even unexploited. In this contribution, we critically evaluate the various efforts, and the (limited) success thereof, in order to introduce standards for defining, designing, assembling, characterizing, and sharing synthetic biology parts. The causes for this success or the lack thereof, as well as possible solutions to overcome these, are discussed. Akin to other engineering disciplines, extensive standardization will undoubtedly speed-up and reduce the cost of bioprocess development. In this respect, further implementation of synthetic biology standards will be crucial for the field in order to redeem its promise, i.e. to enable predictable forward engineering.

Biological Dynamics Markup Language (BDML): an open format for representing quantitative biological dynamics data

PubMed Central

Kyoda, Koji; Tohsato, Yukako; Ho, Kenneth H. L.; Onami, Shuichi

2015-01-01

Motivation: Recent progress in live-cell imaging and modeling techniques has resulted in generation of a large amount of quantitative data (from experimental measurements and computer simulations) on spatiotemporal dynamics of biological objects such as molecules, cells and organisms. Although many research groups have independently dedicated their efforts to developing software tools for visualizing and analyzing these data, these tools are often not compatible with each other because of different data formats. Results: We developed an open unified format, Biological Dynamics Markup Language (BDML; current version: 0.2), which provides a basic framework for representing quantitative biological dynamics data for objects ranging from molecules to cells to organisms. BDML is based on Extensible Markup Language (XML). Its advantages are machine and human readability and extensibility. BDML will improve the efficiency of development and evaluation of software tools for data visualization and analysis. Availability and implementation: A specification and a schema file for BDML are freely available online at http://ssbd.qbic.riken.jp/bdml/. Contact: sonami@riken.jp Supplementary Information: Supplementary data are available at Bioinformatics online. PMID:25414366

Biological Dynamics Markup Language (BDML): an open format for representing quantitative biological dynamics data.

PubMed

Kyoda, Koji; Tohsato, Yukako; Ho, Kenneth H L; Onami, Shuichi

2015-04-01

Recent progress in live-cell imaging and modeling techniques has resulted in generation of a large amount of quantitative data (from experimental measurements and computer simulations) on spatiotemporal dynamics of biological objects such as molecules, cells and organisms. Although many research groups have independently dedicated their efforts to developing software tools for visualizing and analyzing these data, these tools are often not compatible with each other because of different data formats. We developed an open unified format, Biological Dynamics Markup Language (BDML; current version: 0.2), which provides a basic framework for representing quantitative biological dynamics data for objects ranging from molecules to cells to organisms. BDML is based on Extensible Markup Language (XML). Its advantages are machine and human readability and extensibility. BDML will improve the efficiency of development and evaluation of software tools for data visualization and analysis. A specification and a schema file for BDML are freely available online at http://ssbd.qbic.riken.jp/bdml/. Supplementary data are available at Bioinformatics online. © The Author 2014. Published by Oxford University Press.

75 FR 4381 - Pesticide Experimental Use Permit; Receipt of Amendment and Extension Application; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... application 29964- EUP-6 from Pioneer Hi-Bred International, Incorporated requesting to amend and extend an existing experimental use permit (EUP) for the following plant-incorporated protectants (PIPs) and their..., and therefore is seeking public comment on the EUP application: Submitter: Pioneer Hi-Bred...

Identifying green infrastructure BMPs for reducing nitrogen export to a Chesapeake Bay agricultural stream: model synthesis and extension of experimental data

EPA Science Inventory

Background/Question/Methods The effectiveness of riparian forest buffers and other green infrastructure for reducing nitrogen export to agricultural streams has been well described experimentally, but a clear understanding of process-level hydrological and biogeochemical control...

Bartlett Experimental Forest

Treesearch

Jane Gamal-Eldin

1998-01-01

The Bartlett Experimental Forest is a field laboratory for research on the ecology and management of northern forest ecosystems. Research on the Bartlett includes: 1) extensive investigations on structure and dynamics of forests at several levels, and developing management alternatives to reflect an array of values and benefits sought by users of forest lands, 2) a...

Meta-analysis as a tool to study crop productivity response to poultry litter application

USDA-ARS?s Scientific Manuscript database

Extensive research on the use of poultry litter (PL) under different agricultural practices in the USA has shown both negative and positive effects on crop productivity (either yield or aboveground biomass). However, these experimental results are substantially dependent on the experimental set-up, ...

Control of Boundary Layers for Aero-optical Applications

DTIC Science & Technology

2015-06-23

range of subsonic and supersonic Mach numbers was developed and shown to correctly predict experimentally-observed reductions. Heating the wall allows...40 3.3 Extension to supersonic speeds...boundary layers at supersonic speeds. Comparing the model prediction to the experimental results, it was speculated that while the pressure effects can

Effective evaluation of privacy protection techniques in visible and thermal imagery

NASA Astrophysics Data System (ADS)

Nawaz, Tahir; Berg, Amanda; Ferryman, James; Ahlberg, Jörgen; Felsberg, Michael

2017-09-01

Privacy protection may be defined as replacing the original content in an image region with a (less intrusive) content having modified target appearance information to make it less recognizable by applying a privacy protection technique. Indeed, the development of privacy protection techniques also needs to be complemented with an established objective evaluation method to facilitate their assessment and comparison. Generally, existing evaluation methods rely on the use of subjective judgments or assume a specific target type in image data and use target detection and recognition accuracies to assess privacy protection. An annotation-free evaluation method that is neither subjective nor assumes a specific target type is proposed. It assesses two key aspects of privacy protection: "protection" and "utility." Protection is quantified as an appearance similarity, and utility is measured as a structural similarity between original and privacy-protected image regions. We performed an extensive experimentation using six challenging datasets (having 12 video sequences), including a new dataset (having six sequences) that contains visible and thermal imagery. The new dataset is made available online for the community. We demonstrate effectiveness of the proposed method by evaluating six image-based privacy protection techniques and also show comparisons of the proposed method over existing methods.

Developing and Evaluating a Target-Background Similarity Metric for Camouflage Detection

PubMed Central

Lin, Chiuhsiang Joe; Chang, Chi-Chan; Liu, Bor-Shong

2014-01-01

Background Measurement of camouflage performance is of fundamental importance for military stealth applications. The goal of camouflage assessment algorithms is to automatically assess the effect of camouflage in agreement with human detection responses. In a previous study, we found that the Universal Image Quality Index (UIQI) correlated well with the psychophysical measures, and it could be a potentially camouflage assessment tool. Methodology In this study, we want to quantify the camouflage similarity index and psychophysical results. We compare several image quality indexes for computational evaluation of camouflage effectiveness, and present the results of an extensive human visual experiment conducted to evaluate the performance of several camouflage assessment algorithms and analyze the strengths and weaknesses of these algorithms. Significance The experimental data demonstrates the effectiveness of the approach, and the correlation coefficient result of the UIQI was higher than those of other methods. This approach was highly correlated with the human target-searching results. It also showed that this method is an objective and effective camouflage performance evaluation method because it considers the human visual system and image structure, which makes it consistent with the subjective evaluation results. PMID:24498310

Theoretical and Experimental Investigation of Random Gust Loads Part I : Aerodynamic Transfer Function of a Simple Wing Configuration in Incompressible Flow

NASA Technical Reports Server (NTRS)

Hakkinen, Raimo J; Richardson, A S , Jr

1957-01-01

Sinusoidally oscillating downwash and lift produced on a simple rigid airfoil were measured and compared with calculated values. Statistically stationary random downwash and the corresponding lift on a simple rigid airfoil were also measured and the transfer functions between their power spectra determined. The random experimental values are compared with theoretically approximated values. Limitations of the experimental technique and the need for more extensive experimental data are discussed.

An analytical and experimental study of crack extension in center-notched composites

NASA Technical Reports Server (NTRS)

Beuth, Jack L., Jr.; Herakovich, Carl T.

1987-01-01

The normal stress ratio theory for crack extension in anisotropic materials is studied analytically and experimentally. The theory is applied within a microscopic-level analysis of a single center notch of arbitrary orientation in a unidirectional composite material. The bulk of the analytical work of this study applies an elasticity solution for an infinite plate with a center line to obtain critical stress and crack growth direction predictions. An elasticity solution for an infinite plate with a center elliptical flaw is also used to obtain qualitative predictions of the location of crack initiation on the border of a rounded notch tip. The analytical portion of the study includes the formulation of a new crack growth theory that includes local shear stress. Normal stress ratio theory predictions are obtained for notched unidirectional tensile coupons and unidirectional Iosipescu shear specimens. These predictions are subsequently compared to experimental results.

Analytical and experimental study of axisymmetric truncated plug nozzle flow fields

NASA Technical Reports Server (NTRS)

Muller, T. J.; Sule, W. P.; Fanning, A. E.; Giel, T. V.; Galanga, F. L.

1972-01-01

Experimental and analytical investigation of the flow field and base pressure of internal-external-expansion truncated plug nozzles are discussed. Experimental results for two axisymmetric, conical plug-cylindrical shroud, truncated plug nozzles are presented for both open and closed wake operations. These results include extensive optical and pressure data covering nozzle flow field and base pressure characteristics, diffuser effects, lip shock strength, Mach disc behaviour, and the recompression and reverse flow regions. Transonic experiments for a special planar transonic section are presented. An extension of the analytical method of Hall and Mueller to include the internal shock wave from the shroud exit is presented for closed wake operation. Results of this analysis include effects on the flow field and base pressure of ambient pressure ratio, nozzle geometry, and the ratio of specific heats. Static thrust is presented as a function of ambient pressure ratio and nozzle geometry. A new transonic solution method is also presented.

Deep eutectic solvent formation: a structural view using molecular dynamics simulations with classical force fields

NASA Astrophysics Data System (ADS)

Mainberger, Sebastian; Kindlein, Moritz; Bezold, Franziska; Elts, Ekaterina; Minceva, Mirjana; Briesen, Heiko

2017-06-01

Deep eutectic solvents (DES) have gained a reputation as inexpensive and easy to handle ionic liquid analogues. This work employs molecular dynamics (MD) to simulate a variety of DES. The hydrogen bond acceptor (HBA) choline chloride was paired with the hydrogen bond donors (HBD) glycerol, 1,4-butanediol, and levulinic acid. Levulinic acid was also paired with the zwitterionic HBA betaine. In order to evaluate the reliability of data MD simulations can provide for DES, two force fields were compared: the Merck Molecular Force Field and the General Amber Force Field with two different sets of partial charges for the latter. The force fields were evaluated by comparing available experimental thermodynamic and transport properties against simulated values. Structural analysis was performed on the eutectic systems and compared to non-eutectic compositions. All force fields could be validated against certain experimental properties, but performance varied depending on the system and property in question. While extensive hydrogen bonding was found for all systems, details about the contribution of individual groups strongly varied among force fields. Interaction potentials revealed that HBA-HBA interactions weaken linearly with increasing HBD ratio, while HBD-HBD interactions grew disproportionally in magnitude, which might hint at the eutectic composition of a system.

Numerical Simulation and Experimental Validation of MIG Welding of T-Joints of Thin Aluminum Plates for Top Class Vehicles

NASA Astrophysics Data System (ADS)

Bonazzi, Enrico; Colombini, Elena; Panari, Davide; Vergnano, Alberto; Leali, Francesco; Veronesi, Paolo

2017-01-01

The integration of experiments with numerical simulations can efficiently support a quick evaluation of the welded joint. In this work, the MIG welding operation on aluminum T-joint thin plate has been studied by the integration of both simulation and experiments. The aim of the paper is to enlarge the global database, to promote the use of thin aluminum sheets in automotive body industries and to provide new data. Since the welding of aluminum thin plates is difficult to control due to high speed of the heat source and high heat flows during heating and cooling, a simulation model could be considered an effective design tool to predict the real phenomena. This integrated approach enables new evaluation possibilities on MIG-welded thin aluminum T-joints, as correspondence between the extension of the microstructural zones and the simulation parameters, material hardness, transient 3D temperature distribution on the surface and inside the material, stresses, strains, and deformations. The results of the mechanical simulations are comparable with the experimental measurements along the welding path, especially considering the variability of the process. The results could well predict the welding-induced distortion, which together with local heating during welding must be anticipated and subsequently minimized and counterbalance.

New Focuses on European Extension Education: The Issues. Proceedings of the European Seminar on Extension Education (10th, Vila Real, Portugal, September 1-9, 1991).

ERIC Educational Resources Information Center

Koehnen, Timothy, Ed.; Cristovao, Artur, Ed.

This proceedings report is organized into four sections dealing respectively with: (1) global issues facing extension education; (2) extension strategies and methods; (3) extension planning and evaluation; and (4) training and curriculum development. The following papers are included: "Extension Science: To Broaden the Scope" (van…

Analysis of statistical and standard algorithms for detecting muscle onset with surface electromyography.

PubMed

Tenan, Matthew S; Tweedell, Andrew J; Haynes, Courtney A

2017-01-01

The timing of muscle activity is a commonly applied analytic method to understand how the nervous system controls movement. This study systematically evaluates six classes of standard and statistical algorithms to determine muscle onset in both experimental surface electromyography (EMG) and simulated EMG with a known onset time. Eighteen participants had EMG collected from the biceps brachii and vastus lateralis while performing a biceps curl or knee extension, respectively. Three established methods and three statistical methods for EMG onset were evaluated. Linear envelope, Teager-Kaiser energy operator + linear envelope and sample entropy were the established methods evaluated while general time series mean/variance, sequential and batch processing of parametric and nonparametric tools, and Bayesian changepoint analysis were the statistical techniques used. Visual EMG onset (experimental data) and objective EMG onset (simulated data) were compared with algorithmic EMG onset via root mean square error and linear regression models for stepwise elimination of inferior algorithms. The top algorithms for both data types were analyzed for their mean agreement with the gold standard onset and evaluation of 95% confidence intervals. The top algorithms were all Bayesian changepoint analysis iterations where the parameter of the prior (p0) was zero. The best performing Bayesian algorithms were p0 = 0 and a posterior probability for onset determination at 60-90%. While existing algorithms performed reasonably, the Bayesian changepoint analysis methodology provides greater reliability and accuracy when determining the singular onset of EMG activity in a time series. Further research is needed to determine if this class of algorithms perform equally well when the time series has multiple bursts of muscle activity.

StreamQRE: Modular Specification and Efficient Evaluation of Quantitative Queries over Streaming Data.

PubMed

Mamouras, Konstantinos; Raghothaman, Mukund; Alur, Rajeev; Ives, Zachary G; Khanna, Sanjeev

2017-06-01

Real-time decision making in emerging IoT applications typically relies on computing quantitative summaries of large data streams in an efficient and incremental manner. To simplify the task of programming the desired logic, we propose StreamQRE, which provides natural and high-level constructs for processing streaming data. Our language has a novel integration of linguistic constructs from two distinct programming paradigms: streaming extensions of relational query languages and quantitative extensions of regular expressions. The former allows the programmer to employ relational constructs to partition the input data by keys and to integrate data streams from different sources, while the latter can be used to exploit the logical hierarchy in the input stream for modular specifications. We first present the core language with a small set of combinators, formal semantics, and a decidable type system. We then show how to express a number of common patterns with illustrative examples. Our compilation algorithm translates the high-level query into a streaming algorithm with precise complexity bounds on per-item processing time and total memory footprint. We also show how to integrate approximation algorithms into our framework. We report on an implementation in Java, and evaluate it with respect to existing high-performance engines for processing streaming data. Our experimental evaluation shows that (1) StreamQRE allows more natural and succinct specification of queries compared to existing frameworks, (2) the throughput of our implementation is higher than comparable systems (for example, two-to-four times greater than RxJava), and (3) the approximation algorithms supported by our implementation can lead to substantial memory savings.

StreamQRE: Modular Specification and Efficient Evaluation of Quantitative Queries over Streaming Data*

PubMed Central

Mamouras, Konstantinos; Raghothaman, Mukund; Alur, Rajeev; Ives, Zachary G.; Khanna, Sanjeev

2017-01-01

Real-time decision making in emerging IoT applications typically relies on computing quantitative summaries of large data streams in an efficient and incremental manner. To simplify the task of programming the desired logic, we propose StreamQRE, which provides natural and high-level constructs for processing streaming data. Our language has a novel integration of linguistic constructs from two distinct programming paradigms: streaming extensions of relational query languages and quantitative extensions of regular expressions. The former allows the programmer to employ relational constructs to partition the input data by keys and to integrate data streams from different sources, while the latter can be used to exploit the logical hierarchy in the input stream for modular specifications. We first present the core language with a small set of combinators, formal semantics, and a decidable type system. We then show how to express a number of common patterns with illustrative examples. Our compilation algorithm translates the high-level query into a streaming algorithm with precise complexity bounds on per-item processing time and total memory footprint. We also show how to integrate approximation algorithms into our framework. We report on an implementation in Java, and evaluate it with respect to existing high-performance engines for processing streaming data. Our experimental evaluation shows that (1) StreamQRE allows more natural and succinct specification of queries compared to existing frameworks, (2) the throughput of our implementation is higher than comparable systems (for example, two-to-four times greater than RxJava), and (3) the approximation algorithms supported by our implementation can lead to substantial memory savings. PMID:29151821

Private Agricultural Extension System in Kenya: Practice and Policy Lessons

ERIC Educational Resources Information Center

Muyanga, Milu; Jayne, T. S.

2008-01-01

Private extension system has been at the centre of a debate triggered by inefficient public agricultural extension. The debate is anchored on the premise that the private sector is more efficient in extension service delivery. This study evaluates the private extension system in Kenya. It employs qualitative and quantitative methods. The results…

Extensibility and stiffness of the hamstrings in patients with nonspecific low back pain.

PubMed

Halbertsma, J P; Göeken, L N; Hof, A L; Groothoff, J W; Eisma, W H

2001-02-01

To investigate the extensibility and stiffness of the hamstrings in patients with nonspecific low back pain (LBP). An experimental design. A university laboratory for human movement analysis in a department of rehabilitation medicine. Forty subjects, a patient group (20) and a healthy control group (20). Subjects laid supine on an examination table with a lift frame, with left leg placed in a sling at the ankle. Straight leg raising, pulling force, and activity of hamstring and back muscles were recorded with electrodes. Patients indicated when they experienced tension or pain. The lift force, leg excursion, pelvic-femoral angle, first sensation of pain, and the electromyogram of the hamstrings and back muscles measured in an experimental straight-leg raising set-up. The patient group showed a significant restriction in range of motion (ROM) and extensibility of the hamstrings compared with the control group. No significant difference in hamstring muscle stiffness can be assessed between both groups. The restricted ROM and the decreased extensibility of the hamstrings in patients with nonspecific LBP is not caused by increased muscle stiffness of the hamstrings, but determined by the stretch tolerance of the patients.

Dental extraction following zoledronate, induces osteonecrosis in rat's jaw.

PubMed

Vidal-Gutiérrez, X; Gómez-Clavel, J-F; Gaitán-Cepeda, L-A

2017-03-01

Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks. Previous attempts to establish an animal model have not sufficiently considered disease features. Our aim was to establish an inexpensive and replicable animal model that develops BRONJ in a short time. Thirty-two male Wistar rats were randomly divided into two groups: control and experimental. In the experimental group, we administered 0.06mg/kg intraperitoneal dose of zoledronic acid (ZA) 7 and 14 days prior to maxillary second molar extraction. At two, four and six weeks after tooth extraction, the animals were euthanized, and we dissected the maxilla following histological procedures. We stained serial slides with hematoxylin and eosin and Masson's trichrome. The samples were harvested for macroscopic, radiologic and histological evaluation of bone changes. At two weeks postextraction, we observed exposed necrotic bone in dental socket areas in experimental groups. Radiological analysis revealed osteolytic lesions accompanied by extensive destruction and sequestrum formation in the same group. Histological examination confirmed the absence of necrotic bone in control groups in contrast with the experimental groups. The percentage of empty lacunae and the number of osteoclasts and the necrotic bone area were significantly increased (p<0.05) in the experimental groups. The animal model using ZA administration to prior dental extraction successfully mimicked human BRONJ lesions. Also, the model was easily replicated, inexpensive and showed different features than other previous BRONJ models.

Investigation of the effect of the ejector on the performance of the pulse detonation engine nozzle extension

NASA Astrophysics Data System (ADS)

Korobov, A. E.; Golovastov, S. V.

2015-11-01

Influence of an ejector nozzle extension on gas flow at a pulse detonation engine was investigated numerically and experimentally. Detonation formation was organized in stoichiometric hydrogen-oxygen mixture in cylindrical detonation tube. Cylindrical ejector was constructed and mounted at the open end of the tube. Thrust, air consumption and parameters of the detonation were measured in single and multiple regimes of operation. Axisymmetric model was used in numerical investigation. Equations of Navies-Stokes were solved using a finite-difference scheme Roe of second order of accuracy. Initial conditions were estimated on a base of experimental data. Numerical results were validated with experiments data.

Real-time Experiment Interface for Biological Control Applications

PubMed Central

Lin, Risa J.; Bettencourt, Jonathan; White, John A.; Christini, David J.; Butera, Robert J.

2013-01-01

The Real-time Experiment Interface (RTXI) is a fast and versatile real-time biological experimentation system based on Real-Time Linux. RTXI is open source and free, can be used with an extensive range of experimentation hardware, and can be run on Linux or Windows computers (when using the Live CD). RTXI is currently used extensively for two experiment types: dynamic patch clamp and closed-loop stimulation pattern control in neural and cardiac single cell electrophysiology. RTXI includes standard plug-ins for implementing commonly used electrophysiology protocols with synchronized stimulation, event detection, and online analysis. These and other user-contributed plug-ins can be found on the website (http://www.rtxi.org). PMID:21096883

Fail Safe, High Temperature Magnetic Bearings

NASA Technical Reports Server (NTRS)

Minihan, Thomas; Palazzolo, Alan; Kim, Yeonkyu; Lei, Shu-Liang; Kenny, Andrew; Na, Uhn Joo; Tucker, Randy; Preuss, Jason; Hunt, Andrew; Carter, Bart;

Evaluating the Impact of Cooperative Extension Outreach via Twitter

ERIC Educational Resources Information Center

O'Neill, Barbara

2014-01-01

Twitter is increasingly being used by Extension educators as a teaching and program-marketing tool. It is not enough, however, to simply use Twitter to disseminate information. Steps must be taken to evaluate program impact with quantitative and qualitative data. This article described the following Twitter evaluation metrics: unique hashtags,…

Extensive Evaluation of Using a Game Project in a Software Architecture Course

ERIC Educational Resources Information Center

Wang, Alf Inge

2011-01-01

This article describes an extensive evaluation of introducing a game project to a software architecture course. In this project, university students have to construct and design a type of software architecture, evaluate the architecture, implement an application based on the architecture, and test this implementation. In previous years, the domain…

Biophysics and clinical practice for regenerative processes in cirrhosis of the liver/of liver cirrhosis assisted by Delta-S Entropy Variation Systems.

PubMed

Marineo, G; Fesce, E

2006-12-01

The therapy in question uses an innovative bioengineering device denoted as ''Delta-S DVD Entropy Variation System''. Previous research indicated regression of cirrhosis as evaluated in its morphofunctional and symptomatological aspects. The aim of the study is to confirm and extend previous experimental observations by enhancing hemodynamic evaluation techniques. In order to clarify scar regression, it was decided to include in the endpoints a quantitative evaluation of portal hypertension called HVPG, which is sensitive to the breakdown of hepatic architecture and the influence of regeneration nodules and therefore the advance of cirrhosis. The experimental design consists of a self-controlled study carried out on Child A-B cirrhosis patients with portal hypertension (hepatic venous pressure gradient, HVPG > or = 10 mmHg). Five patients were enrolled, 4 HCV positive, one with autoimmune cirrhosis, all showing extensive symptoms. At the end of the treatment all patients showed a reduction in portal hypertension (mean reduction HVPG = 40.2%, P<0.011), together with an improved ultrasound flowmeter pattern and a sharp decrease or disappearance of the symptoms. No adverse effects were reported. Efficacy on autoimmune cirrhosis was unaffected. By means of a quantitative analysis of portal hypertension and of functional aspects, this study confirms that the Delta-S DVD system can lead to the regression of the scar component of cirrhosis, promote the regeneration of functioning liver tissue with positive effects on hepatic functionality and prevent symptoms and the risk of varicose vein rupture.

Ab initio thermodynamic model for magnesium carbonates and hydrates.

PubMed

Chaka, Anne M; Felmy, Andrew R

2014-09-04

An ab initio thermodynamic framework for predicting properties of hydrated magnesium carbonate minerals has been developed using density-functional theory linked to macroscopic thermodynamics through the experimental chemical potentials for MgO, water, and CO2. Including semiempirical dispersion via the Grimme method and small corrections to the generalized gradient approximation of Perdew, Burke, and Ernzerhof for the heat of formation yields a model with quantitative agreement for the benchmark minerals brucite, magnesite, nesquehonite, and hydromagnesite. The model shows how small differences in experimental conditions determine whether nesquehonite, hydromagnesite, or magnesite is the result of laboratory synthesis from carbonation of brucite, and what transformations are expected to occur on geological time scales. Because of the reliance on parameter-free first-principles methods, the model is reliably extensible to experimental conditions not readily accessible to experiment and to any mineral composition for which the structure is known or can be hypothesized, including structures containing defects, substitutions, or transitional structures during solid state transformations induced by temperature changes or processes such as water, CO2, or O2 diffusion. Demonstrated applications of the ab initio thermodynamic framework include an independent means to evaluate differences in thermodynamic data for lansfordite, predicting the properties of Mg analogues of Ca-based hydrated carbonates monohydrocalcite and ikaite, which have not been observed in nature, and an estimation of the thermodynamics of barringtonite from the stoichiometry and a single experimental observation.

Turbulence Modeling Validation, Testing, and Development

NASA Technical Reports Server (NTRS)

Bardina, J. E.; Huang, P. G.; Coakley, T. J.

1997-01-01

The primary objective of this work is to provide accurate numerical solutions for selected flow fields and to compare and evaluate the performance of selected turbulence models with experimental results. Four popular turbulence models have been tested and validated against experimental data often turbulent flows. The models are: (1) the two-equation k-epsilon model of Wilcox, (2) the two-equation k-epsilon model of Launder and Sharma, (3) the two-equation k-omega/k-epsilon SST model of Menter, and (4) the one-equation model of Spalart and Allmaras. The flows investigated are five free shear flows consisting of a mixing layer, a round jet, a plane jet, a plane wake, and a compressible mixing layer; and five boundary layer flows consisting of an incompressible flat plate, a Mach 5 adiabatic flat plate, a separated boundary layer, an axisymmetric shock-wave/boundary layer interaction, and an RAE 2822 transonic airfoil. The experimental data for these flows are well established and have been extensively used in model developments. The results are shown in the following four sections: Part A describes the equations of motion and boundary conditions; Part B describes the model equations, constants, parameters, boundary conditions, and numerical implementation; and Parts C and D describe the experimental data and the performance of the models in the free-shear flows and the boundary layer flows, respectively.

Vegetation and Ecological Characteristics of Mixed-Conifer and Red Fir Forests at the Teakettle Experimental Forest

Treesearch

Malcolm North; Brian Oakley; Jiquan Chen; Heather Erickson; Andrew Gray; Antonio Izzo; Dale Johnson; Siyan Ma; Jim Marra; Marc Meyer; Kathryn Purcell; Tom Rambo; Dave Rizzo; Brent Roath; Tim Schowalter

2002-01-01

Detailed analysis of mixed-conifer and red fir forests were made from extensive, large vegetation sampling, systematically conducted throughout the Teakettle Experimental Forest. Mixed conifer is characterized by distinct patch conditions of closed-canopy tree clusters, persistent gaps and shrub thickets. This heterogeneous spatial structure provides contrasting...

77 FR 21587 - Pratt and Whitney; A Subsidiary of United Technologies Corporation Cheshire Engine Center...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-10

... Whitney A Subsidiary of United Technologies Corporation Far Group and Experimental Test Group East... Technologies Corporation, FAR Group and Experimental Test Group, supplies/supports and operates as an extension... Test Group. The amended notice applicable to TA-W-75,152 is hereby issued as follows: ``All workers of...

76 FR 3135 - Pesticide Experimental Use Permit; Receipt of Extension Application;

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPP-2009-0608; FRL-8855-3] Pesticide Experimental Use... (PIP) [Event 5307] Bacillus thuringiensis eCry3.1Ab protein and the genetic material necessary for its production (vector pSYN12274) in Event 5307 corn (SYN-[Oslash]53[Oslash]7-1) and combined and single trait...

Improving single molecule force spectroscopy through automated real-time data collection and quantification of experimental conditions

PubMed Central

Scholl, Zackary N.; Marszalek, Piotr E.

2013-01-01

The benefits of single molecule force spectroscopy (SMFS) clearly outweigh the challenges which include small sample sizes, tedious data collection and introduction of human bias during the subjective data selection. These difficulties can be partially eliminated through automation of the experimental data collection process for atomic force microscopy (AFM). Automation can be accomplished using an algorithm that triages usable force-extension recordings quickly with positive and negative selection. We implemented an algorithm based on the windowed fast Fourier transform of force-extension traces that identifies peaks using force-extension regimes to correctly identify usable recordings from proteins composed of repeated domains. This algorithm excels as a real-time diagnostic because it involves <30 ms computational time, has high sensitivity and specificity, and efficiently detects weak unfolding events. We used the statistics provided by the automated procedure to clearly demonstrate the properties of molecular adhesion and how these properties change with differences in the cantilever tip and protein functional groups and protein age. PMID:24001740

Discovering Technicolor

NASA Astrophysics Data System (ADS)

Andersen, J. R.; Antipin, O.; Azuelos, G.; Del Debbio, L.; Del Nobile, E.; Di Chiara, S.; Hapola, T.; Järvinen, M.; Lowdon, P. J.; Maravin, Y.; Masina, I.; Nardecchia, M.; Pica, C.; Sannino, F.

2011-09-01

We provide a pedagogical introduction to extensions of the Standard Model in which the Higgs is composite. These extensions are known as models of dynamical electroweak symmetry breaking or, in brief, Technicolor. Material covered includes: motivations for Technicolor, the construction of underlying gauge theories leading to minimal models of Technicolor, the comparison with electroweak precision data, the low-energy effective theory, the spectrum of the states common to most of the Technicolor models, the decays of the composite particles and the experimental signals at the Large Hadron Collider. The level of the presentation is aimed at readers familiar with the Standard Model but who have little or no prior exposure to Technicolor. Several extensions of the Standard Model featuring a composite Higgs can be reduced to the effective Lagrangian introduced in the text. We establish the relevant experimental benchmarks for Vanilla, Running, Walking, and Custodial Technicolor, and a natural fourth family of leptons, by laying out the framework to discover these models at the Large Hadron Collider.

Role of muscle mass and mode of contraction in circulatory responses to exercise

NASA Technical Reports Server (NTRS)

Lewis, S. F.; Snell, P. G.; Pettinger, W. A.; Blomqvist, C. G.; Taylor, W. F.; Hamra, M.; Graham, R. M.

1985-01-01

The roles of the mode of contraction (dynamic or static) and active muscle mass in determining the cardiovascular response to exercise has been investigated experimentally in six normal men. Exercise consisted of static handgrip and dynamic handgrip exercise, and static and dynamic knee extension for a period of six minutes. Observed increases in mean arterial pressure after exercise were similar for each mode of contraction, but larger for knee extension than handgrip exercise. Cardiac output increased more for dynamic than for static exercise and for each mode more for knee exercise than for handgrip exercise. Systemic resistance was found to be lower for dynamic than for static exercise, and to decrease from resisting levels by about one third during dynamic knee extension. It is shown that the magnitude of cardiovascular response is related to active muscle mass, but is independent of the contraction mode. Equalization of cardiovascular response was achieved by proportionately larger increases in cardiac output during dynamic exercise. The complete experimental results are given in a table.

Productive extension of semantic memory in school-aged children: Relations with reading comprehension and deployment of cognitive resources.

PubMed

Bauer, Patricia J; Blue, Shala N; Xu, Aoxiang; Esposito, Alena G

2016-07-01

We investigated 7- to 10-year-old children's productive extension of semantic memory through self-generation of new factual knowledge derived through integration of separate yet related facts learned through instruction or through reading. In Experiment 1, an experimenter read the to-be-integrated facts. Children successfully learned and integrated the information and used it to further extend their semantic knowledge, as evidenced by high levels of correct responses in open-ended and forced-choice testing. In Experiment 2, on half of the trials, the to-be-integrated facts were read by an experimenter (as in Experiment 1) and on half of the trials, children read the facts themselves. Self-generation performance was high in both conditions (experimenter- and self-read); in both conditions, self-generation of new semantic knowledge was related to an independent measure of children's reading comprehension. In Experiment 3, the way children deployed cognitive resources during reading was predictive of their subsequent recall of newly learned information derived through integration. These findings indicate self-generation of new semantic knowledge through integration in school-age children as well as relations between this productive means of extension of semantic memory and cognitive processes engaged during reading. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Productive Extension of Semantic Memory in School-aged Children: Relations with Reading Comprehension and Deployment of Cognitive Resources

PubMed Central

Bauer, Patricia J.; Blue, Shala N.; Xu, Aoxiang; Esposito, Alena G.

2016-01-01

We investigated 7- to 10-year-old children’s productive extension of semantic memory through self-generation of new factual knowledge derived through integration of separate yet related facts learned through instruction or through reading. In Experiment 1, an experimenter read the to-be-integrated facts. Children successfully learned and integrated the information and used it to further extend their semantic knowledge, as evidenced by high levels of correct responses in open-ended and forced-choice testing. In Experiment 2, on half of the trials, the to-be-integrated facts were read by an experimenter (as in Experiment 1) and on half of the trials, children read the facts themselves. Self-generation performance was high in both conditions (experimenter- and self-read); in both conditions, self-generation of new semantic knowledge was related to an independent measure of children’s reading comprehension. In Experiment 3, the way children deployed cognitive resources during reading was predictive of their subsequent recall of newly learned information derived through integration. These findings indicate self-generation of new semantic knowledge through integration in school-age children as well as relations between this productive means of extension of semantic memory and cognitive processes engaged during reading. PMID:27253263

Sup wit Eval Ext?

ERIC Educational Resources Information Center

Patton, Michael Quinn

2008-01-01

Extension and evaluation share some similar challenges, including working with diverse stakeholders, parallel processes for focusing priorities, meeting common standards of excellence, and adapting to globalization, new technologies, and changing times. Evaluations of extension programs have helped clarify how change occurs, especially the…

77 FR 46750 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-06

... Questionnaire Testing, Evaluation, and Research.'' The proposed collection will utilize qualitative and quantitative methodologies to pretest questionnaires and validate EIA survey forms data quality, including..., Evaluation, and Research; (3) Type of Request: Extension, Without Change, of a Previously Approved Collection...

Fast state estimation subject to random data loss in discrete-time nonlinear stochastic systems

NASA Astrophysics Data System (ADS)

Mahdi Alavi, S. M.; Saif, Mehrdad

2013-12-01

This paper focuses on the design of the standard observer in discrete-time nonlinear stochastic systems subject to random data loss. By the assumption that the system response is incrementally bounded, two sufficient conditions are subsequently derived that guarantee exponential mean-square stability and fast convergence of the estimation error for the problem at hand. An efficient algorithm is also presented to obtain the observer gain. Finally, the proposed methodology is employed for monitoring the Continuous Stirred Tank Reactor (CSTR) via a wireless communication network. The effectiveness of the designed observer is extensively assessed by using an experimental tested-bed that has been fabricated for performance evaluation of the over wireless-network estimation techniques under realistic radio channel conditions.

Recovery from distal ulnar motor conduction block injury: serial EMG studies.

PubMed

Montoya, Liliana; Felice, Kevin J

2002-07-01

Acute conduction block injuries often result from nerve compression or trauma. The temporal pattern of clinical, electrophysiologic, and histopathologic changes following these injuries has been extensively studied in experimental animal models but not in humans. Our recent evaluation of a young man with an injury to the deep motor branch of the ulnar nerve following nerve compression from weightlifting exercises provided the opportunity to follow the course and recovery of a severe conduction block injury with sequential nerve conduction studies. The conduction block slowly and completely resolved, as did the clinical deficit, over a 14-week period. The reduction in conduction block occurred at a linear rate of -6.1% per week. Copyright 2002 Wiley Periodicals, Inc.

Finger Vein Recognition Based on a Personalized Best Bit Map

PubMed Central

Yang, Gongping; Xi, Xiaoming; Yin, Yilong

2012-01-01

Finger vein patterns have recently been recognized as an effective biometric identifier. In this paper, we propose a finger vein recognition method based on a personalized best bit map (PBBM). Our method is rooted in a local binary pattern based method and then inclined to use the best bits only for matching. We first present the concept of PBBM and the generating algorithm. Then we propose the finger vein recognition framework, which consists of preprocessing, feature extraction, and matching. Finally, we design extensive experiments to evaluate the effectiveness of our proposal. Experimental results show that PBBM achieves not only better performance, but also high robustness and reliability. In addition, PBBM can be used as a general framework for binary pattern based recognition. PMID:22438735

Advances and trends in the development of computational models for tires

NASA Technical Reports Server (NTRS)

Noor, A. K.; Tanner, J. A.

1985-01-01

Status and some recent developments of computational models for tires are summarized. Discussion focuses on a number of aspects of tire modeling and analysis including: tire materials and their characterization; evolution of tire models; characteristics of effective finite element models for analyzing tires; analysis needs for tires; and impact of the advances made in finite element technology, computational algorithms, and new computing systems on tire modeling and analysis. An initial set of benchmark problems has been proposed in concert with the U.S. tire industry. Extensive sets of experimental data will be collected for these problems and used for evaluating and validating different tire models. Also, the new Aircraft Landing Dynamics Facility (ALDF) at NASA Langley Research Center is described.

Low data rate digital space communications

NASA Technical Reports Server (NTRS)

Chen, C. H.

1973-01-01

The low available transmitter power and the large frequency uncertainty constrain the data rate to be low. An all-digital communication receiver is proposed, and its feasibility is established. Although coherent systems should be used whenever practical, the noncoherent MFSK system is more suitable for very low data rates. The effect of Rician fading on the performance of MFSK receiver is studied. Fading characteristics of the Venus channel are examined based on the exponential model and available experimental data on the Venus atmosphere. Because of the requirement of high communication efficiency, three codes are evaluated and compared. The rapidly varying phase error at low data rate has great effects on the tracking loop behaviors which are examined by extensive computer study of the phase plane trajectories.

Finger vein recognition based on a personalized best bit map.

PubMed

Yang, Gongping; Xi, Xiaoming; Yin, Yilong

2012-01-01

Finger vein patterns have recently been recognized as an effective biometric identifier. In this paper, we propose a finger vein recognition method based on a personalized best bit map (PBBM). Our method is rooted in a local binary pattern based method and then inclined to use the best bits only for matching. We first present the concept of PBBM and the generating algorithm. Then we propose the finger vein recognition framework, which consists of preprocessing, feature extraction, and matching. Finally, we design extensive experiments to evaluate the effectiveness of our proposal. Experimental results show that PBBM achieves not only better performance, but also high robustness and reliability. In addition, PBBM can be used as a general framework for binary pattern based recognition.

Collision Detection for Underwater ROV Manipulator Systems

PubMed Central

Rossi, Matija; Dooly, Gerard; Toal, Daniel

2018-01-01

Work-class ROVs equipped with robotic manipulators are extensively used for subsea intervention operations. Manipulators are teleoperated by human pilots relying on visual feedback from the worksite. Operating in a remote environment, with limited pilot perception and poor visibility, manipulator collisions which may cause significant damage are likely to happen. This paper presents a real-time collision detection algorithm for marine robotic manipulation. The proposed collision detection mechanism is developed, integrated into a commercial ROV manipulator control system, and successfully evaluated in simulations and experimental setup using a real industry standard underwater manipulator. The presented collision sensing solution has a potential to be a useful pilot assisting tool that can reduce the task load, operational time, and costs of subsea inspection, repair, and maintenance operations. PMID:29642396

Collision Detection for Underwater ROV Manipulator Systems.

PubMed

Sivčev, Satja; Rossi, Matija; Coleman, Joseph; Omerdić, Edin; Dooly, Gerard; Toal, Daniel

2018-04-06

Work-class ROVs equipped with robotic manipulators are extensively used for subsea intervention operations. Manipulators are teleoperated by human pilots relying on visual feedback from the worksite. Operating in a remote environment, with limited pilot perception and poor visibility, manipulator collisions which may cause significant damage are likely to happen. This paper presents a real-time collision detection algorithm for marine robotic manipulation. The proposed collision detection mechanism is developed, integrated into a commercial ROV manipulator control system, and successfully evaluated in simulations and experimental setup using a real industry standard underwater manipulator. The presented collision sensing solution has a potential to be a useful pilot assisting tool that can reduce the task load, operational time, and costs of subsea inspection, repair, and maintenance operations.

Human guinea pigs and the ethics of experimentation: the BMJ's correspondent at the Nuremberg medical trial.

PubMed

Weindling, P

1996-12-07

Though the Nuremberg medical trial was a United States military tribunal, British forensic pathologists supplied extensive evidence for the trial. The BMJ had a correspondent at the trial, and he endorsed a utilitarian legitimation of clinical experiments, justifying the medical research carried out under Nazism as of long term scientific benefit despite the human costs. The British supported an international medical commission to evaluate the ethics and scientific quality of German research. Medical opinions differed over whether German medical atrocities should be given publicity or treated in confidence. The BMJ's correspondent warned against medical researchers being taken over by a totalitarian state, and these arguments were used to oppose the NHS and any state control over medical research.

Combined invariants to similarity transformation and to blur using orthogonal Zernike moments

PubMed Central

Beijing, Chen; Shu, Huazhong; Zhang, Hui; Coatrieux, Gouenou; Luo, Limin; Coatrieux, Jean-Louis

2011-01-01

The derivation of moment invariants has been extensively investigated in the past decades. In this paper, we construct a set of invariants derived from Zernike moments which is simultaneously invariant to similarity transformation and to convolution with circularly symmetric point spread function (PSF). Two main contributions are provided: the theoretical framework for deriving the Zernike moments of a blurred image and the way to construct the combined geometric-blur invariants. The performance of the proposed descriptors is evaluated with various PSFs and similarity transformations. The comparison of the proposed method with the existing ones is also provided in terms of pattern recognition accuracy, template matching and robustness to noise. Experimental results show that the proposed descriptors perform on the overall better. PMID:20679028

78 FR 36571 - Extension of Post-Sale Evaluation Period for Central Gulf of Mexico Planning Area Lease Sale 227

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... DEPARTMENT OF THE INTERIOR Bureau of Ocean Energy Management [MMAA104000] Extension of Post-Sale Evaluation Period for Central Gulf of Mexico Planning Area Lease Sale 227 AGENCY: Bureau of Ocean Energy Management (BOEM), Interior. ACTION: Notice to Extend Post-Sale Evaluation Period. SUMMARY: This notice...

[Giant epidermoid cyst of the skull with extra and intracranial extension. A case report].

PubMed

Akhaddar, A; Gazzaz, M; El Mostarchid, B; Kadiri, B; Lrhezzioui, J; Boucetta, M

2002-09-01

Intradiploic epidermoid cyst of the skull is a rare clinical entity that can exceptionally grow to a large size with intracranial extension. The authors report the case of a 38-year-old man with a giant epidermoid cyst of the parietal bone with extra and intracranial extension, presenting with focal neurological symptoms. The diagnosis was suggested at imaging (skull radiographs, CT and MRI), and confirmed at histology. Complete removal of the cyst and its capsule was performed followed by cranioplasty. Postoperatively, the patient was discharged free of symptoms. CT scan provides good evaluation of the bony lesion and may suggest intracranial extension. MRI is superior for evaluation of cerebral compression. The pathogenesis, clinical presentation, diagnostic evaluation and therapeutic management of these rare lesions are reviewed.

Structural impact response for assessing railway vibration induced on buildings

NASA Astrophysics Data System (ADS)

Kouroussis, Georges; Mouzakis, Harris P.; Vogiatzis, Konstantinos E.

2018-03-01

Over the syears, the rapid growth in railway infrastructure has led to numerous environmental challenges. One such significant issue, particularly in urban areas, is ground-borne vibration. A common source of ground-borne vibration is caused by local defects (e.g. rail joints, switches, turnouts, etc.) that generate large amplitude excitations at isolated locations. Modelling these excitation sources is particularly challenging and requires the use of complex and extensive computational efforts. For some situations, the use of experiments and measured data offers a rapid way to estimate the effect of such defects and to evaluate the railway vibration levels using a scoping approach. In this paper, the problem of railway-induced ground vibrations is presented along with experimental studies to assess the ground vibration and ground borne noise levels, with a particular focus on the structural response of sensitive buildings. The behaviour of particular building foundations is evaluated through experimental data collected in Brussels Region, by presenting the expected frequency responses for various types of buildings, taking into account both the soil-structure interaction and the tramway track response. A second study is dedicated to the Athens metro, where transmissibility functions are used to analyse the effect of various Athenian building face to metro network trough comprehensive measurement campaigns. This allows the verification of appropriate vibration mitigation measures. These benchmark applications based on experimental results have been proved to be efficient to treat a complex problem encountered in practice in urban areas, where the urban rail network interacts with important local defects and where the rise of railway ground vibration problems has clearly been identified.

Computational Fluid Dynamics Modeling of Submerged Objects Under Unidirectional and Oscillatory Flows.

NASA Astrophysics Data System (ADS)

Fytanidis, D. K.; Wu, H.; Landry, B. J.; Garcia, M. H.

2017-12-01

Abandoned Unexploded Ordnances (UXOs) from wartime events, accidents, training or other military activities can be found in coastal environments. While the interest for these hazardous submerged objects is increased, there are still existing knowledge gaps regarding the mechanisms of incipient motion and flow behavior around UXOs lying on the seafloor. Numerical modeling of flow around near bed placed UXOs is conducted for unidirectional and oscillatory flow conditions using Computational Fluid Dynamics techniques. The Reynolds-Averaged Navier-Stokes (RANS) approach is used to simulate the complex turbulent flow field around UXOs. The numerical results are compared with two-dimensional Particle Image Velocimetry measurements from experiments conducted in unidirectional and oscillatory flow facilities within the Ven Te Chow Hydrosystems Laboratory to evaluate the accuracy of the applied RANS-based solver. Realistic boundary conditions are imposed in the numerical models to mimic the experimental conditions in the laboratory facilities. The comparison between the numerical results and the experimental data agrees well. In addition, the effect of the angle of attack on the forces that UXOs experience is examined. Numerical results suggest that the orientation of UXOs with respect to the mean flow is an important parameter for incipient motion under critical flow conditions which is in agreement with prior laboratory experimental results regarding the identification of critical flow conditions for the initiation of motion of UXOs. Finally, an extensive parametric analysis is conducted to evaluate the effect of the maximum current velocity and wave characteristics (maximum velocity and period) on the flow forces and the mean flow pattern around the objects.

Applying Experiments Designed to an Extension Course in Astronomy for High School Students

NASA Astrophysics Data System (ADS)

Rosado, Ricardo Meloni Martins; Mota, Aline Tiara

2015-07-01

This paper presents some experimental activities conducted in an extension course in Astronomy applied to high school students from public and private schools in a town located in the state of Minas Gerais. Seven activities were chosen, among others, to report the impressions of the authors. Some suggestions of application that may be helpful to others teachers are also made.

Improvements to the nuclear model code GNASH for cross section calculations at higher energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, P.G.; Chadwick, M.B.

1994-05-01

The nuclear model code GNASH, which in the past has been used predominantly for incident particle energies below 20 MeV, has been modified extensively for calculations at higher energies. The model extensions and improvements are described in this paper, and their significance is illustrated by comparing calculations with experimental data for incident energies up to 160 MeV.

Bio-Inspired Human-Level Machine Learning

DTIC Science & Technology

2015-10-25

extensions to high-level cognitive functions such as anagram solving problem. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF...extensions to high-level cognitive functions such as anagram solving problem. We expect that the bio-inspired human-level machine learning combined with...numbers of 1011 neurons and 1014 synaptic connections in the human brain. In previous work, we experimentally demonstrated the feasibility of cognitive

OTSEGO COUNTY EXPERIMENTAL PROGRAM FOR TESTING METHODS OF FORMING FARM MANAGEMENT STUDY GROUPS, A PROGRESS REPORT. EXTENSION STUDY, NUMBER 8.

ERIC Educational Resources Information Center

LONGEST, JAMES W.; GENGENBACK, WILLIAM H.

THE MOST FREQUENT METHOD OF GROUP FORMATION FOR INTENSIVE FARM MANAGEMENT PROGRAMS IN NEW YORK STATE HAS BEEN TO COMBINE ALL INTERESTED FARMERS IN LARGE GROUPS AT THE COUNTY EXTENSION HEADQUARTERS. THIS EXPERIMENT WAS SET UP TO STUDY THE EFFECTIVENESS OF TWO METHODS OF FORMING SMALL GROUPS--BY SOCIOMETRIC CHOICE OR SIMILAR CHARACTERISTICS. ALL…

Evaluation of coated columbium test panels having application to a secondary nozzle extension for the RL10 rocket engine system, parts 1 and 2

NASA Technical Reports Server (NTRS)

Murphy, Kenneth S.; Castro, Joaquin H.

1988-01-01

The activity performed on the screening and evaluation of various coatings for application on columbium alloy test panels representative of a radiation-cooled nozzle extension for the RL10 rocket engine is summarized. Vendors and processes of candidate coatings were evaluated. Post engine test evaluations of the two selected coatings are discussed.

Effects of a home-exercise therapy programme on cervical and lumbar range of motion among nurses with neck and lower back pain: a quasi-experimental study.

PubMed

Freimann, Tiina; Merisalu, Eda; Pääsuke, Mati

2015-01-01

Cervical and lumbar range of motion limitations are usually associated with musculoskeletal pain in the neck and lower back, and are a major health problem among nurses. Physical exercise has been evaluated as an effective intervention method for improving cervical and lumbar range of motion, and for preventing and reducing musculoskeletal pain. The purpose of this study was to investigate the effects of a home-exercise therapy programme on cervical and lumbar range of motion among intensive care unit nurses who had experienced mild to moderate musculoskeletal pain in the neck and or lower back during the previous six months. A quasi-experimental study was conducted among intensive care unit nurses at Tartu University Hospital (Estonia) between May and July 2011. Thirteen nurses who had suffered musculoskeletal pain episodes in the neck and or lower back during the previous six months underwent an 8-week home-exercise therapy programme. Eleven nurses without musculoskeletal pain formed a control group. Questions from the Nordic Musculoskeletal Questionnaire and the 11-point Visual Analogue Scale were used to select potential participants for the experimental group via an assessment of the prevalence and intensity of musculoskeletal pain. Cervical range of motion and lumbar range of motion in flexion, extension, lateral flexion and (cervical range of motion only) rotation were measured with a digital goniometer. A paired t-test was used to compare the measured parameters before and after the home-exercise therapy programme. A Student's t-test was used to analyse any differences between the experimental and control groups. After the home-exercise therapy, there was a significant increase (p < 0.05) in cervical range of motion in flexion, extension, lateral flexion and rotation, and in lumbar range of motion in lateral flexion. Cervical range of motion in flexion was significantly higher (p < 0.01) in the experimental group compared to the control group after therapy. Our results suggest an 8-week intensive home-exercise therapy programme may improve cervical and lumbar range of motion among intensive care nurses. Further studies are needed to develop this simple but effective home-exercise therapy programme to help motivate nurses to perform such exercises regularly. Current Controlled Trials ISRCTN19278735. Registered 27 November 2015.

A unified framework for the evaluation of surrogate endpoints in mental-health clinical trials.

PubMed

Molenberghs, Geert; Burzykowski, Tomasz; Alonso, Ariel; Assam, Pryseley; Tilahun, Abel; Buyse, Marc

2010-06-01

For a number of reasons, surrogate endpoints are considered instead of the so-called true endpoint in clinical studies, especially when such endpoints can be measured earlier, and/or with less burden for patient and experimenter. Surrogate endpoints may occur more frequently than their standard counterparts. For these reasons, it is not surprising that the use of surrogate endpoints in clinical practice is increasing. Building on the seminal work of Prentice(1) and Freedman et al.,(2) Buyse et al. (3) framed the evaluation exercise within a meta-analytic setting, in an effort to overcome difficulties that necessarily surround evaluation efforts based on a single trial. In this article, we review the meta-analytic approach for continuous outcomes, discuss extensions to non-normal and longitudinal settings, as well as proposals to unify the somewhat disparate collection of validation measures currently on the market. Implications for design and for predicting the effect of treatment in a new trial, based on the surrogate, are discussed. A case study in schizophrenia is analysed.

Structure and mechanical behavior of human hair.

PubMed

Yu, Yang; Yang, Wen; Wang, Bin; Meyers, Marc André

2017-04-01

The understanding of the mechanical behavior of hair under various conditions broadens our knowledge in biological materials science and contributes to the cosmetic industry. The hierarchical organization of hair is studied from the intermediate filament to the structural levels. The effects of strain rate, relative humidity, and temperature are evaluated. Hair exhibits a high tensile strength, 150-270MPa, which is significantly dependent on strain rate and humidity. The strain-rate sensitivity, approximately 0.06-0.1, is comparable to that of other keratinous materials and common synthetic polymers. The structures of the internal cortex and surface cuticle are affected by the large tensile extension. One distinguishing feature, the unwinding of the α-helix and the possible transformation to β-sheet structure of keratin under tension, which affects the ductility of hair, is analytically evaluated and incorporated into a constitutive equation. A good agreement with the experimental results is obtained. This model elucidates the tensile response of the α-keratin fibers. The contributions of elastic and plastic strains on reloading are evaluated and correlated to structural changes. Copyright © 2016 Elsevier B.V. All rights reserved.

Extension Education: Training Coordinators to Facilitate Distance Education through the Assemblies of God Bible Institute in Belize

ERIC Educational Resources Information Center

Castleberry, Terry Lane

2010-01-01

The specific objective of this project was to train coordinators to open new extension classes and effectively facilitate existing extension classes offered by the Assemblies of God Bible Institute (AGBI) in Belize. Extensive biblical and literary research and a thorough evaluation of current extension classes led to the development of a…

2016 All Bugs Good and Bad Webinar Series - eXtension

Science.gov Websites

Urban Agriculture, Texas A&M AgriLife Extension and Clemson Cooperative Extension. Series / NIFA This work is supported by the USDA National Institute of Food and Agriculture, New Technologies Internationalizing Extension Network Literacy Program Evaluation Volunteer Administration Women in Agriculture

ENDF/B-VII.0: Next Generation Evaluated Nuclear Data Library for Nuclear Science and Technology

NASA Astrophysics Data System (ADS)

Chadwick, M. B.; Obložinský, P.; Herman, M.; Greene, N. M.; McKnight, R. D.; Smith, D. L.; Young, P. G.; MacFarlane, R. E.; Hale, G. M.; Frankle, S. C.; Kahler, A. C.; Kawano, T.; Little, R. C.; Madland, D. G.; Moller, P.; Mosteller, R. D.; Page, P. R.; Talou, P.; Trellue, H.; White, M. C.; Wilson, W. B.; Arcilla, R.; Dunford, C. L.; Mughabghab, S. F.; Pritychenko, B.; Rochman, D.; Sonzogni, A. A.; Lubitz, C. R.; Trumbull, T. H.; Weinman, J. P.; Brown, D. A.; Cullen, D. E.; Heinrichs, D. P.; McNabb, D. P.; Derrien, H.; Dunn, M. E.; Larson, N. M.; Leal, L. C.; Carlson, A. D.; Block, R. C.; Briggs, J. B.; Cheng, E. T.; Huria, H. C.; Zerkle, M. L.; Kozier, K. S.; Courcelle, A.; Pronyaev, V.; van der Marck, S. C.

2006-12-01

We describe the next generation general purpose Evaluated Nuclear Data File, ENDF/B-VII.0, of recommended nuclear data for advanced nuclear science and technology applications. The library, released by the U.S. Cross Section Evaluation Working Group (CSEWG) in December 2006, contains data primarily for reactions with incident neutrons, protons, and photons on almost 400 isotopes, based on experimental data and theory predictions. The principal advances over the previous ENDF/B-VI library are the following: (1) New cross sections for U, Pu, Th, Np and Am actinide isotopes, with improved performance in integral validation criticality and neutron transmission benchmark tests; (2) More precise standard cross sections for neutron reactions on H, 6Li, 10B, Au and for 235,238U fission, developed by a collaboration with the IAEA and the OECD/NEA Working Party on Evaluation Cooperation (WPEC); (3) Improved thermal neutron scattering; (4) An extensive set of neutron cross sections on fission products developed through a WPEC collaboration; (5) A large suite of photonuclear reactions; (6) Extension of many neutron- and proton-induced evaluations up to 150 MeV; (7) Many new light nucleus neutron and proton reactions; (8) Post-fission beta-delayed photon decay spectra; (9) New radioactive decay data; (10) New methods for uncertainties and covariances, together with covariance evaluations for some sample cases; and (11) New actinide fission energy deposition. The paper provides an overview of this library, consisting of 14 sublibraries in the same ENDF-6 format as the earlier ENDF/B-VI library. We describe each of the 14 sublibraries, focusing on neutron reactions. Extensive validation, using radiation transport codes to simulate measured critical assemblies, show major improvements: (a) The long-standing underprediction of low enriched uranium thermal assemblies is removed; (b) The 238U and 208Pb reflector biases in fast systems are largely removed; (c) ENDF/B-VI.8 good agreement for simulations of thermal high-enriched uranium assemblies is preserved; (d) The underprediction of fast criticality of 233,235U and 239Pu assemblies is removed; and (e) The intermediate spectrum critical assemblies are predicted more accurately. We anticipate that the new library will play an important role in nuclear technology applications, including transport simulations supporting national security, nonproliferation, advanced reactor and fuel cycle concepts, criticality safety, fusion, medicine, space applications, nuclear astrophysics, and nuclear physics facility design. The ENDF/B-VII.0 library is archived at the National Nuclear Data Center, BNL, and can be retrieved from www.nndc.bnl.gov.

Pest management in traditional maize stores in West Africa: a farmer's perspective.

PubMed

Meikle, W G; Markham, R H; Nansen, C; Holst, N; Degbey, P; Azoma, K; Korie, S

2002-10-01

Farmers in the Republic of Benin have few resources to invest in protection of stored maize, and prophylactic pesticide application is often recommended by extension and development agencies. Neither the efficacy nor profitability of such an application in traditional maize storage facilities has been addressed quantitatively. In this study, existing management options for stored maize were evaluated monthly over 6 mo in central and southern Benin with respect to their effects on grain injury and on densities of Prostephanus truncatus (Horn) and Sitophilus zeamais Motschulsky. P. truncatus infested 54% of the experimental stores in the study even though Teretrius nigrescens (Lewis), a natural enemy introduced against P. truncatus, was well established in the region. S. zeamais was the most common pest, found in 85% of the experimental storage facilities. Prophylactically treated maize was, on average, worth more than untreated maize for month 1 through 5 in southern Benin, after taking into account market price, pesticide costs, percentage grain damage and weight loss, but maize storage was not profitable overall. No difference was observed between treatments in central Benin. After 6 mo treated storage facilities were not significantly different from untreated storage facilities in terms of either percentage damage or profit in either region. A rapid scouting plan intended to provide farmers with a means for identifying storage facilities at greatest risk of severe P. truncatus infestation was field validated. Given that unsafe pesticide use is prevalent in Benin, research and extension services should clearly state the limitations to prophylactic treatment and increase the effort to educate farmers on appropriate pesticide use, store monitoring and marketing.

Mathematical models of cytotoxic effects in endpoint tumor cell line assays: critical assessment of the application of a single parametric value as a standard criterion to quantify the dose-response effects and new unexplored proposal formats.

PubMed

Calhelha, Ricardo C; Martínez, Mireia A; Prieto, M A; Ferreira, Isabel C F R

2017-10-23

The development of convenient tools for describing and quantifying the effects of standard and novel therapeutic agents is essential for the research community, to perform more precise evaluations. Although mathematical models and quantification criteria have been exchanged in the last decade between different fields of study, there are relevant methodologies that lack proper mathematical descriptions and standard criteria to quantify their responses. Therefore, part of the relevant information that can be drawn from the experimental results obtained and the quantification of its statistical reliability are lost. Despite its relevance, there is not a standard form for the in vitro endpoint tumor cell lines' assays (TCLA) that enables the evaluation of the cytotoxic dose-response effects of anti-tumor drugs. The analysis of all the specific problems associated with the diverse nature of the available TCLA used is unfeasible. However, since most TCLA share the main objectives and similar operative requirements, we have chosen the sulforhodamine B (SRB) colorimetric assay for cytotoxicity screening of tumor cell lines as an experimental case study. In this work, the common biological and practical non-linear dose-response mathematical models are tested against experimental data and, following several statistical analyses, the model based on the Weibull distribution was confirmed as the convenient approximation to test the cytotoxic effectiveness of anti-tumor compounds. Then, the advantages and disadvantages of all the different parametric criteria derived from the model, which enable the quantification of the dose-response drug-effects, are extensively discussed. Therefore, model and standard criteria for easily performing the comparisons between different compounds are established. The advantages include a simple application, provision of parametric estimations that characterize the response as standard criteria, economization of experimental effort and enabling rigorous comparisons among the effects of different compounds and experimental approaches. In all experimental data fitted, the calculated parameters were always statistically significant, the equations proved to be consistent and the correlation coefficient of determination was, in most of the cases, higher than 0.98.

Ultrasonic Nondestructive Evaluation Techniques Applied to the Quantitative Characterization of Textile Composite Materials

NASA Technical Reports Server (NTRS)

Miller, James G.

1997-01-01

In this Progress Report, we describe our recent developments of advanced ultrasonic nondestructive evaluation methods applied to the characterization of anisotropic materials. We present images obtained from experimental measurements of ultrasonic diffraction patterns for a thin woven composite in an immersion setup. In addition, we compare apparent signal loss measurements of the thin woven composite for phase-sensitive and phase-insensitive detection methods. All images of diffraction patterns have been included on the accompanying CD-ROM in the Adobe(Trademark) Portable Document Format (PDF). Due to the extensive amount of data, however, hardcopies of only a small representative selection of the images are included within the printed report. This Progress Report presents experimental results that support successful implementation of single element as well as one and two-dimensional ultrasonic array technologies for the inspection of textile composite structures. In our previous reports, we have addressed issues regarding beam profiles of ultrasonic pressure fields transmitted through a water reference path and transmitted through a thin woven composite sample path. Furthermore, we presented experimental results of the effect of a thin woven composite on the magnitude of an insonifying ultrasonic pressure field. In addition to the study of ultrasonic beam profiles, we consider issues relevant to the application of single-element, one-dimensional, and two-dimensional array technologies towards probing the mechanical properties of advanced engineering composites and structures. We provide comparisons between phase-sensitive and phase-insensitive detection methods for determination of textile composite structure parameters. We also compare phase-sensitive and phase-insensitive - - ---- ----- apparent signal loss measurements in an effort to study the phenomenon of phase cancellation at the face of a finite-aperture single-element receiver. Furthermore, in this Progress Report we extend our work on ultrasonic beam profile issues through investigation of the phase fronts of the pressure field. In Section H of this Progress Report we briefly describe the experimental arrangement and methods for data acquisition of the ultrasonic diffraction patterns upon transmission through a thin woven composite. Section III details the analysis of the experimental data followed by the experimental results in Section IV. Finally, a discussion of the observations and conclusions is found in Section V.

A Capsule-Type Electromagnetic Acoustic Transducer for Fast Screening of External Corrosion in Nonmagnetic Pipes.

PubMed

Li, Yong; Cai, Rui; Yan, Bei; Zainal Abidin, Ilham Mukriz; Jing, Haoqing; Wang, Yi

2018-05-28

For fuel transmission and structural strengthening, small-diameter pipes of nonmagnetic materials are extensively adopted in engineering fields including aerospace, energy, transportation, etc. However, the hostile and corrosive environment leaves them vulnerable to external corrosion which poses a severe threat to structural integrity of pipes. Therefore, it is imperative to nondestructively detect and evaluate the external corrosion in nonmagnetic pipes. In light of this, a capsule-type Electromagnetic Acoustic Transducer (EMAT) for in-situ nondestructive evaluation of nonmagnetic pipes and fast screening of external corrosion is proposed in this paper. A 3D hybrid model for efficient prediction of responses from the proposed transducer to external corrosion is established. Closed-form expressions of field quantities of electromagnetics and EMAT signals are formulated. Simulations based on the hybrid model indicate feasibility of the proposed transducer in detection and evaluation of external corrosion in nonmagnetic pipes. In parallel, experiments with the fabricated transducer have been carried out. Experimental results are supportive of the conclusion drawn from simulations. The investigation via simulations and experiments implies that the proposed capsule-type EMAT is capable of fast screening of external corrosion, which is beneficial to the in-situ nondestructive evaluation of small-diameter nonmagnetic pipes.

EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols

PubMed Central

Kalina, T; Flores-Montero, J; van der Velden, V H J; Martin-Ayuso, M; Böttcher, S; Ritgen, M; Almeida, J; Lhermitte, L; Asnafi, V; Mendonça, A; de Tute, R; Cullen, M; Sedek, L; Vidriales, M B; Pérez, J J; te Marvelde, J G; Mejstrikova, E; Hrusak, O; Szczepański, T; van Dongen, J J M; Orfao, A

2012-01-01

The EU-supported EuroFlow Consortium aimed at innovation and standardization of immunophenotyping for diagnosis and classification of hematological malignancies by introducing 8-color flow cytometry with fully standardized laboratory procedures and antibody panels in order to achieve maximally comparable results among different laboratories. This required the selection of optimal combinations of compatible fluorochromes and the design and evaluation of adequate standard operating procedures (SOPs) for instrument setup, fluorescence compensation and sample preparation. Additionally, we developed software tools for the evaluation of individual antibody reagents and antibody panels. Each section describes what has been evaluated experimentally versus adopted based on existing data and experience. Multicentric evaluation demonstrated high levels of reproducibility based on strict implementation of the EuroFlow SOPs and antibody panels. Overall, the 6 years of extensive collaborative experiments and the analysis of hundreds of cell samples of patients and healthy controls in the EuroFlow centers have provided for the first time laboratory protocols and software tools for fully standardized 8-color flow cytometric immunophenotyping of normal and malignant leukocytes in bone marrow and blood; this has yielded highly comparable data sets, which can be integrated in a single database. PMID:22948490

Delaminated rotator cuff tear: extension of delamination and cuff integrity after arthroscopic rotator cuff repair.

PubMed

Gwak, Heui-Chul; Kim, Chang-Wan; Kim, Jung-Han; Choo, Hye-Jeung; Sagong, Seung-Yeob; Shin, John

2015-05-01

The purpose of this study was to evaluate the extension of delamination and the cuff integrity after arthroscopic repair of delaminated rotator cuff tears. Sixty-five patients with delaminated rotator cuff tears were retrospectively reviewed. The delaminated tears were divided into full-thickness delaminated tears and partial-thickness delaminated tears. To evaluate the medial extension, we calculated the coronal size of the delaminated portion. To evaluate the posterior extension, we checked the tendon involved. Cuff integrity was evaluated by computed tomography arthrography. The mean medial extension in the full-thickness and partial-thickness delaminated tears was 18.1 ± 6.0 mm and 22.7 ± 6.3 mm, respectively (P = .0084). The posterior extension into the supraspinatus and the infraspinatus was 36.9% and 32.3%, respectively, in the full-thickness delaminated tears, and it was 27.7% and 3.1%, respectively, in the partial-thickness delaminated tears (P = .0043). With regard to cuff integrity, 35 cases of anatomic healing, 10 cases of partial healing defects, and 17 cases of retear were detected. Among the patients with retear and partial healing of the defect, all the partially healed defects showed delamination. Three retear patients showed delamination, and 14 retear patients did not show delamination; the difference was statistically significant (P = .0001). The full-thickness delaminated tears showed less medial extension and more posterior extension than the partial-thickness delaminated tears. Delamination did not develop in retear patients, but delamination was common in the patients with partially healed defects. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Comparative Bacterial Proteomics: Analysis of the Core Genome Concept

PubMed Central

Callister, Stephen J.; McCue, Lee Ann; Turse, Joshua E.; Monroe, Matthew E.; Auberry, Kenneth J.; Smith, Richard D.; Adkins, Joshua N.; Lipton, Mary S.

2008-01-01

While comparative bacterial genomic studies commonly predict a set of genes indicative of common ancestry, experimental validation of the existence of this core genome requires extensive measurement and is typically not undertaken. Enabled by an extensive proteome database developed over six years, we have experimentally verified the expression of proteins predicted from genomic ortholog comparisons among 17 environmental and pathogenic bacteria. More exclusive relationships were observed among the expressed protein content of phenotypically related bacteria, which is indicative of the specific lifestyles associated with these organisms. Although genomic studies can establish relative orthologous relationships among a set of bacteria and propose a set of ancestral genes, our proteomics study establishes expressed lifestyle differences among conserved genes and proposes a set of expressed ancestral traits. PMID:18253490

The Synthesis of Single-Subject Experimental Data: Extensions of the Basic Multilevel Model

ERIC Educational Resources Information Center

Van den Noortgate, Wim; Moeyaert, Mariola; Ugille, Maaike; Beretvas, Tasha; Ferron, John

2014-01-01

Due to an increasing interest in the use of single-subject experimental designs (SSEDs), appropriate techniques are needed to analyze this type of data. The purpose of this paper proposal is to present four studies (Beretvas, Hembry, Van den Noortgate, & Ferron, 2013; Bunuan, Hembry & Beretvas, 2013; Moeyaert, Ugille, Ferron, Beretvas,…

Experimental measurements and numerical modeling of marginal burning in live chaparral fuel beds

Treesearch

X. Zhou; D.R. Weise; S Mahalingam

2005-01-01

An extensive experimental and numerical study was completed to analyze the marginal burning behavior of live chaparral shrub fuels that grow in the mountains of southern California. Laboratory fire spread experiments were carried out to determine the effects of wind, slope, moisture content, and fuel characteristics on marginal burning in fuel beds of common...

A Dynamic Calibration Method for Experimental and Analytical Hub Load Comparison

DTIC Science & Technology

2017-03-01

minimal differences were noted. As discussed above, a “dummy” four- bladed hub was fabricated to permit application of shaker loads to the ARES testbed...experimental data used for comparison was from wind-tunnel testing of a set of Active-Twist Rotor (ATR) blades , which had undergone extensive bench...experimental measurements, one low-speed and the other high-speed. Although these blades are capable of actively twisting during flight, in both of these

Using iPads as a Data Collection Tool in Extension Programming Evaluation

ERIC Educational Resources Information Center

Rowntree, J. E.; Witman, R. R.; Lindquist, G. L.; Raven, M. R.

2013-01-01

Program evaluation is an important part of Extension, especially with the increased emphasis on metrics and accountability. Agents are often the point persons for evaluation data collection, and Web-based surveys are a commonly used tool. The iPad tablet with Internet access has the potential to be an effective survey tool. iPads were field tested…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yokosawa, A.

An extensive amount of data were obtained from measurements of protonproton elastic scattering up to 5 GeV/c. We summarize physics learned from these data as well as other related experimental results.

Implicit personality theory in evaluation of brand extensions.

PubMed

Flaherty, K E; Pappas, J M

2000-06-01

Transference, the extent to which consumers transfer their opinions of a parent brand to a new extension, is critical to the success of any brand-extension strategy. Past research has shown that transference is a complex process that varies among persons depending upon an implicit personality theory, entity versus incremental. In a laboratory experiment analysis of ratings for 100 21-yr.-old undergraduates of attitude, perceived fit and risk, prior product involvement, and implicit personality theory (entity versus incremental) the influence of consumers' implicit personality theory on transference was considered within the brand-extension context. As expected, the amount of transference differed between those espousing entity and incremental theories. "Entity theorists" were much more likely to transfer feelings associated with the parent brand to the new extension than were "incremental theorists" who did not rely on prior brand information when forming evaluations of a new extension. This effect did not occur when perceived fit between the parent brand and the extension was high.

Bulk Growth of Wide Band Gap II-VI Compound Semiconductors by Physical Vapor Transport

NASA Technical Reports Server (NTRS)

Su, Ching-Hua

1997-01-01

The mechanism of physical vapor transport of II-VI semiconducting compounds was studied both theoretically, using a one-dimensional diffusion model, as well as experimentally. It was found that the vapor phase stoichiometry is critical in determining the vapor transport rate. The experimental heat treatment methods to control the vapor composition over the starting materials were investigated and the effectiveness of the heat treatments was confirmed by partial pressure measurements using an optical absorption technique. The effect of residual (foreign) gas on the transport rate was also studies theoretically by the diffusion model and confirmed experimentally by the measurements of total pressure and compositions of the residual gas. An in-situ dynamic technique for the transport rate measurements and a further extension of the technique that simultaneously measured the partial pressures and transport rates were performed and, for the first time, the experimentally determined mass fluxes were compared with those calculated, without any adjustable parameters, from the diffusion model. Using the information obtained from the experimental transport rate measurements as guideline high quality bulk crystal of wide band gap II-VI semiconductor were grown from the source materials which undergone the same heat treatment methods. The grown crystals were then extensively characterized with emphasis on the analysis of the crystalline structural defects.

Rocket Engine Turbine Blade Surface Pressure Distributions Experiment and Computations

NASA Technical Reports Server (NTRS)

Hudson, Susan T.; Zoladz, Thomas F.; Dorney, Daniel J.; Turner, James (Technical Monitor)

2002-01-01

Understanding the unsteady aspects of turbine rotor flow fields is critical to successful future turbine designs. A technology program was conducted at NASA's Marshall Space Flight Center to increase the understanding of unsteady environments for rocket engine turbines. The experimental program involved instrumenting turbine rotor blades with miniature surface mounted high frequency response pressure transducers. The turbine model was then tested to measure the unsteady pressures on the rotor blades. The data obtained from the experimental program is unique in two respects. First, much more unsteady data was obtained (several minutes per set point) than has been possible in the past. Also, an extensive steady performance database existed for the turbine model. This allowed an evaluation of the effect of the on-blade instrumentation on the turbine's performance. A three-dimensional unsteady Navier-Stokes analysis was also used to blindly predict the unsteady flow field in the turbine at the design operating conditions and at +15 degrees relative incidence to the first-stage rotor. The predicted time-averaged and unsteady pressure distributions show good agreement with the experimental data. This unique data set, the lessons learned for acquiring this type of data, and the improvements made to the data analysis and prediction tools are contributing significantly to current Space Launch Initiative turbine airflow test and blade surface pressure prediction efforts.

Patterns of shading tolerance determined from experimental ...

EPA Pesticide Factsheets

An extensive review of the experimental literature on seagrass shading evaluated the relationship between experimental light reductions, duration of experiment and seagrass response metrics to determine whether there were consistent statistical patterns. There were highly significant linear relationships of both percent biomass and percent shoot density reduction versus percent light reduction (versus controls), although unexplained variation in the data were high. Duration of exposure affected extent of response for both metrics, but was more clearly a factor in biomass response. Both biomass and shoot density showed linear responses to duration of light reduction for treatments 60%. Unexplained variation was again high, and greater for shoot density than biomass. With few exceptions, regressions of both biomass and shoot density on light reduction for individual species and for genera were statistically significant, but also tended to show high degrees of variability in data. Multivariate regressions that included both percent light reduction and duration of reduction as dependent variables increased the percentage of variation explained in almost every case. Analysis of response data by seagrass life history category (Colonizing, Opportunistic, Persistent) did not yield clearly separate response relationships in most cases. Biomass tended to show somewhat less variation in response to light reduction than shoot density, and of the two, may be the prefe

Model validations for low-global warming potential refrigerants in mini-split air-conditioning units

DOE PAGES

Shen, Bo; Shrestha, Som; Abdelaziz, Omar

2016-09-02

To identify low GWP (global warming potential) refrigerants to replace R-22 and R-410A, extensive experimental evaluations were conducted for multiple candidates of refrigerant at the standard test conditions and at high-ambient conditions with outdoor temperature varying from 27.8 C to 55.0 C.. In the study, R-22 was compared to propane (R-290), DR-3, ARM-20B, N-20B and R-444B in a mini-split air conditioning unit originally designed for R-22; R-410A was compared to R-32, DR-55, ARM-71A, L41-2 (R-447A) in a mini-split unit designed for R-410A. To reveal physics behind the measured performance results, thermodynamic properties of the alternative refrigerants were analysed. In addition,more » the experimental data was used to calibrate a physics-based equipment model, i.e. ORNL Heat Pump Design Model (HPDM). The calibrated model translated the experimental results to key calculated parameters, i.e. compressor efficiencies, refrigerant side two-phase heat transfer coefficients, corresponding to each refrigerant. As a result, these calculated values provide scientific insights on the performance of the alternative refrigerants and are useful for other applications beyond mini-split air conditioning units.« less

Model validations for low-global warming potential refrigerants in mini-split air-conditioning units

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Bo; Shrestha, Som; Abdelaziz, Omar

To identify low GWP (global warming potential) refrigerants to replace R-22 and R-410A, extensive experimental evaluations were conducted for multiple candidates of refrigerant at the standard test conditions and at high-ambient conditions with outdoor temperature varying from 27.8 C to 55.0 C.. In the study, R-22 was compared to propane (R-290), DR-3, ARM-20B, N-20B and R-444B in a mini-split air conditioning unit originally designed for R-22; R-410A was compared to R-32, DR-55, ARM-71A, L41-2 (R-447A) in a mini-split unit designed for R-410A. To reveal physics behind the measured performance results, thermodynamic properties of the alternative refrigerants were analysed. In addition,more » the experimental data was used to calibrate a physics-based equipment model, i.e. ORNL Heat Pump Design Model (HPDM). The calibrated model translated the experimental results to key calculated parameters, i.e. compressor efficiencies, refrigerant side two-phase heat transfer coefficients, corresponding to each refrigerant. As a result, these calculated values provide scientific insights on the performance of the alternative refrigerants and are useful for other applications beyond mini-split air conditioning units.« less

Extension's Online Presence: Are Land-Grant Universities Promoting the Tripartite Mission?

ERIC Educational Resources Information Center

Arnold, Shannon; Hill, Alexandra; Bailey, Nikki; Meyers, Courtney

2012-01-01

Land-grant universities were established with a tripartite mission: education, research, and outreach through the Cooperative Extension Service. The purpose of the study reported here was to evaluate the online presence and technological adoptions of Extension on land-grant university, college of agriculture, and state Extension websites. Almost…

The Impacts of the Great Recession on State Natural Resource Extension Programs

ERIC Educational Resources Information Center

Serenari, Christopher; Peterson, M. Nils; Bardon, Robert E.; Brown, Robert D.

2013-01-01

The Great Recession contributed to major budget cuts for natural resource Extension programs in the United States. Despite the potentially large cuts, their impacts and how Extension has adapted their programs have not been evaluated. We begin addressing these needs with surveys of Association of Natural Resource Extension Professionals members…

EXTENSION IN RURAL COMMUNITIES, A MANUAL FOR AGRICULTURAL AND HOME EXTENSION WORKERS.

ERIC Educational Resources Information Center

SAVILE, A.H.

A PRACTICAL GUIDE IS PROVIDED FOR TRAINERS OF ADVISORY AND EXTENSION WORKERS AND LOCAL LEADERS IN AGRICULTURE AND COMMUNITY DEVELOPMENT IN DEVELOPING NATIONS. BASIC PRINCIPLES OF AGRICULTURAL EXTENSION, COMMUNITY SURVEY PROCEDURES, ELEMENTS OF PROGRAM PLANNING, AND PURPOSES AND METHODS OF PROGRAM EVALUATION ARE DESCRIBED. THEN FOLLOW TWO CHAPTERS…

Knee extension isometric torque production differences based on verbal motivation given to introverted and extroverted female children.

PubMed

McWhorter, J Wesley; Landers, Merrill; Young, Daniel; Puentedura, E Louie; Hickman, Robbin A; Brooksby, Candi; Liveratti, Marc; Taylor, Lisa

2011-08-01

To date, little research has been conducted to test the efficacy of different forms of motivation based on a female child's personality type. The purpose of this study was to evaluate the ability of female children to perform a maximal knee extension isometric torque test with varying forms of motivation, based on the child's personality type (introvert vs. extrovert). The subjects were asked to perform a maximal isometric knee extension test under three different conditions: 1) with no verbal motivation, 2) with verbal motivation from the evaluator only, and 3) with verbal motivation from a group of their peers and the evaluator combined. A 2×3 mixed ANOVA was significant for an interaction (F 2,62=17.530; p<0.0005). Post hoc testing for the introverted group showed that scores without verbal motivation were significantly higher than with verbal motivation from the evaluator or the evaluator plus the peers. The extroverted group revealed that scores with verbal motivation from the evaluator or the evaluator plus the peers were significantly higher than without verbal motivation. Results suggest that verbal motivation has a varying effect on isometric knee extension torque production in female children with different personality types. Extroverted girls perform better with motivation, whereas introverted girls perform better without motivation from others.

Logo Effects on Brand Extension Evaluations from the Electrophysiological Perspective.

PubMed

Shang, Qian; Pei, Guanxiong; Dai, Shenyi; Wang, Xiaoyi

2017-01-01

Brand extension typically has two strategies: brand name extension (BN) and brand logo extension (BL). The current study explored which strategy (BN or BL) better enhanced the success of dissimilar brand extension and product promotion in enterprises. Event-related potentials (ERPs) were used to investigate electrophysiological processes when subjects evaluated their acceptance of the brand extension using a combined picture of S1 and S2. S1 was a famous brand presented by two identity signs (brand name and brand logo). S2 was a picture of an extension product that belonged to a dissimilar product category than S1. The behavior data showed that BL was more acceptable than BN in the dissimilar brand extension. The neurophysiology process was reflected by a less negative N2 component and a larger P300 component in the BL than in the BN. We suggested that N2 reflected a whole conflict between the brand-product combination and the long-term memory and that P300 could be regarded as the reflection of the categorization process in the working memory.

Logo Effects on Brand Extension Evaluations from the Electrophysiological Perspective

PubMed Central

Shang, Qian; Pei, Guanxiong; Dai, Shenyi; Wang, Xiaoyi

2017-01-01

Brand extension typically has two strategies: brand name extension (BN) and brand logo extension (BL). The current study explored which strategy (BN or BL) better enhanced the success of dissimilar brand extension and product promotion in enterprises. Event-related potentials (ERPs) were used to investigate electrophysiological processes when subjects evaluated their acceptance of the brand extension using a combined picture of S1 and S2. S1 was a famous brand presented by two identity signs (brand name and brand logo). S2 was a picture of an extension product that belonged to a dissimilar product category than S1. The behavior data showed that BL was more acceptable than BN in the dissimilar brand extension. The neurophysiology process was reflected by a less negative N2 component and a larger P300 component in the BL than in the BN. We suggested that N2 reflected a whole conflict between the brand-product combination and the long-term memory and that P300 could be regarded as the reflection of the categorization process in the working memory. PMID:28337121

Broadband Scattering from Sand and Sand/Mud Sediments with Extensive Environmental Characterization

DTIC Science & Technology

2017-01-30

experiment , extensive envi- ronmental characterization was also performed to support data/model comparisons for both experimental efforts. The site...mechanisms, potentially addressing questions left unresolved from the previous sediment acoustics experiments , SAX99 and SAX04. This work was also to provide...environmental characterization to support the analysis of data collected during the Target and Reverberation Experiment in 2013 (TREX13) as well as

Experimental and analytical investigation of dynamic characteristics of extension-twist-coupled composite tubular spars

NASA Astrophysics Data System (ADS)

Lake, Renee C.; Izadpanah, Amir P.; Baucom, Robert M.

1993-02-01

The results from a study aimed at improving the dynamic and aerodynamic characteristics of composite rotor blades through the use of extension-twist coupling are presented. A set of extension-twist-coupled composite spars was manufactured with four plies of graphite-epoxy cloth prepreg. These spars were noncircular in cross-section design and were therefore subject to warping deformations. Three different cross-sectional geometries were developed: D-shape, square, and flattened ellipse. Three spars of each type were fabricated to assess the degree of repeatability in the manufacturing process of extension-twist-coupled structures. Results from free-free vibration tests of the spars were compared with results from normal modes and frequency analyses of companion shell-finite-element models. Five global modes were identified within the frequency range from 0 to 2000 Hz for each spar. The experimental results for only one D-shape spar could be determined, however, and agreed within 13.8 percent of the analytical results. Frequencies corresponding to the five global modes for the three square spars agreed within 9.5, 11.6, and 8.5 percent of the respective analytical results and for the three elliptical spars agreed within 4.9, 7.7, and 9.6 percent of the respective analytical results.

Experimental and analytical investigation of dynamic characteristics of extension-twist-coupled composite tubular spars

NASA Technical Reports Server (NTRS)

Lake, Renee C.; Izadpanah, Amir P.; Baucom, Robert M.

1993-01-01

The results from a study aimed at improving the dynamic and aerodynamic characteristics of composite rotor blades through the use of extension-twist coupling are presented. A set of extension-twist-coupled composite spars was manufactured with four plies of graphite-epoxy cloth prepreg. These spars were noncircular in cross-section design and were therefore subject to warping deformations. Three different cross-sectional geometries were developed: D-shape, square, and flattened ellipse. Three spars of each type were fabricated to assess the degree of repeatability in the manufacturing process of extension-twist-coupled structures. Results from free-free vibration tests of the spars were compared with results from normal modes and frequency analyses of companion shell-finite-element models. Five global modes were identified within the frequency range from 0 to 2000 Hz for each spar. The experimental results for only one D-shape spar could be determined, however, and agreed within 13.8 percent of the analytical results. Frequencies corresponding to the five global modes for the three square spars agreed within 9.5, 11.6, and 8.5 percent of the respective analytical results and for the three elliptical spars agreed within 4.9, 7.7, and 9.6 percent of the respective analytical results.

Preface of "The Second Symposium on Border Zones Between Experimental and Numerical Application Including Solution Approaches By Extensions of Standard Numerical Methods"

NASA Astrophysics Data System (ADS)

Ortleb, Sigrun; Seidel, Christian

2017-07-01

In this second symposium at the limits of experimental and numerical methods, recent research is presented on practically relevant problems. Presentations discuss experimental investigation as well as numerical methods with a strong focus on application. In addition, problems are identified which require a hybrid experimental-numerical approach. Topics include fast explicit diffusion applied to a geothermal energy storage tank, noise in experimental measurements of electrical quantities, thermal fluid structure interaction, tensegrity structures, experimental and numerical methods for Chladni figures, optimized construction of hydroelectric power stations, experimental and numerical limits in the investigation of rain-wind induced vibrations as well as the application of exponential integrators in a domain-based IMEX setting.

Theory and simulations of covariance mapping in multiple dimensions for data analysis in high-event-rate experiments

NASA Astrophysics Data System (ADS)

Zhaunerchyk, V.; Frasinski, L. J.; Eland, J. H. D.; Feifel, R.

2014-05-01

Multidimensional covariance analysis and its validity for correlation of processes leading to multiple products are investigated from a theoretical point of view. The need to correct for false correlations induced by experimental parameters which fluctuate from shot to shot, such as the intensity of self-amplified spontaneous emission x-ray free-electron laser pulses, is emphasized. Threefold covariance analysis based on simple extension of the two-variable formulation is shown to be valid for variables exhibiting Poisson statistics. In this case, false correlations arising from fluctuations in an unstable experimental parameter that scale linearly with signals can be eliminated by threefold partial covariance analysis, as defined here. Fourfold covariance based on the same simple extension is found to be invalid in general. Where fluctuations in an unstable parameter induce nonlinear signal variations, a technique of contingent covariance analysis is proposed here to suppress false correlations. In this paper we also show a method to eliminate false correlations associated with fluctuations of several unstable experimental parameters.

The Relaxation Matrix for Symmetric Tops with Inversion Symmetry. II; Line Mixing Effects in the V1 Band of NH3

NASA Technical Reports Server (NTRS)

Boulet, C.; Ma, Q.

2016-01-01

Line mixing effects have been calculated in the ?1 parallel band of self-broadened NH3. The theoretical approach is an extension of a semi-classical model to symmetric-top molecules with inversion symmetry developed in the companion paper [Q. Ma and C. Boulet, J. Chem. Phys. 144, 224303 (2016)]. This model takes into account line coupling effects and hence enables the calculation of the entire relaxation matrix. A detailed analysis of the various coupling mechanisms is carried out for Q and R inversion doublets. The model has been applied to the calculation of the shape of the Q branch and of some R manifolds for which an obvious signature of line mixing effects has been experimentally demonstrated. Comparisons with measurements show that the present formalism leads to an accurate prediction of the available experimental line shapes. Discrepancies between the experimental and theoretical sets of first order mixing parameters are discussed as well as some extensions of both theory and experiment.

Capturing Cyclic Variability in EGR Dilute SI Combustion using Multi-Cycle RANS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scarcelli, Riccardo; Sevik, James; Wallner, Thomas

Dilute combustion is an effective approach to increase the thermal efficiency of spark-ignition (SI) internal combustion engines (ICEs). However, high dilution levels typically result in large cycle-to-cycle variations (CCV) and poor combustion stability, therefore limiting the efficiency improvement. In order to extend the dilution tolerance of SI engines, advanced ignition systems are the subject of extensive research. When simulating the effect of the ignition characteristics on CCV, providing a numerical result matching the measured average in-cylinder pressure trace does not deliver useful information regarding combustion stability. Typically Large Eddy Simulations (LES) are performed to simulate cyclic engine variations, since Reynold-Averagedmore » Navier-Stokes (RANS) modeling is expected to deliver an ensemble-averaged result. In this paper it is shown that, when using RANS, the cyclic perturbations coming from different initial conditions at each cycle are not damped out even after many simulated cycles. As a result, multi-cycle RANS results feature cyclic variability. This allows evaluating the effect of advanced ignition sources on combustion stability but requires validation against the entire cycle-resolved experimental dataset. A single-cylinder GDI research engine is simulated using RANS and the numerical results for 20 consecutive engine cycles are evaluated for several operating conditions, including stoichiometric as well as EGR dilute operation. The effect of the ignition characteristics on CCV is also evaluated. Results show not only that multi-cycle RANS simulations can capture cyclic variability and deliver similar trends as the experimental data, but more importantly that RANS might be an effective, lower-cost alternative to LES for the evaluation of ignition strategies for combustion systems that operate close to the stability limit.« less

Analysis of statistical and standard algorithms for detecting muscle onset with surface electromyography

PubMed Central

Tweedell, Andrew J.; Haynes, Courtney A.

2017-01-01

The timing of muscle activity is a commonly applied analytic method to understand how the nervous system controls movement. This study systematically evaluates six classes of standard and statistical algorithms to determine muscle onset in both experimental surface electromyography (EMG) and simulated EMG with a known onset time. Eighteen participants had EMG collected from the biceps brachii and vastus lateralis while performing a biceps curl or knee extension, respectively. Three established methods and three statistical methods for EMG onset were evaluated. Linear envelope, Teager-Kaiser energy operator + linear envelope and sample entropy were the established methods evaluated while general time series mean/variance, sequential and batch processing of parametric and nonparametric tools, and Bayesian changepoint analysis were the statistical techniques used. Visual EMG onset (experimental data) and objective EMG onset (simulated data) were compared with algorithmic EMG onset via root mean square error and linear regression models for stepwise elimination of inferior algorithms. The top algorithms for both data types were analyzed for their mean agreement with the gold standard onset and evaluation of 95% confidence intervals. The top algorithms were all Bayesian changepoint analysis iterations where the parameter of the prior (p0) was zero. The best performing Bayesian algorithms were p0 = 0 and a posterior probability for onset determination at 60–90%. While existing algorithms performed reasonably, the Bayesian changepoint analysis methodology provides greater reliability and accuracy when determining the singular onset of EMG activity in a time series. Further research is needed to determine if this class of algorithms perform equally well when the time series has multiple bursts of muscle activity. PMID:28489897

Mid-career faculty development in academic medicine: How does it impact faculty and institutional vitality?

PubMed Central

Campion, MaryAnn W.; Bhasin, Robina M.; Beaudette, Donald J.; Shann, Mary H.; Benjamin, Emelia J.

2016-01-01

Purpose Faculty vitality is integral to the advancement of higher education. Strengthening vitality is particularly important for mid-career faculty, who represent the largest and most dissatisfied segment. The demands of academic medicine appear to be another factor that may put faculty at risk of attrition. To address these issues, we initiated a ten-month mid-career faculty development program. Methods A mixed-methods quasi-experimental design was used to evaluate the program's impact on faculty and institutional vitality. Pre/post surveys compared participants with a matched reference group. Quantitative data were augmented by interviews and focus groups with multiple stakeholders. Results At the program's conclusion, participants showed statistically significant gains in knowledge, skills, attitudes, and connectivity when compared to the referents. Conclusion Given that mid-career faculty development in academic medicine has not been extensively studied, our evaluation provides a useful perspective to guide future initiatives aimed at enhancing the vitality and leadership capacity of mid-career faculty. PMID:27942418

Quantitative evaluation of hidden defects in cast iron components using ultrasound activated lock-in vibrothermography.

PubMed

Montanini, R; Freni, F; Rossi, G L

2012-09-01

This paper reports one of the first experimental results on the application of ultrasound activated lock-in vibrothermography for quantitative assessment of buried flaws in complex cast parts. The use of amplitude modulated ultrasonic heat generation allowed selective response of defective areas within the part, as the defect itself is turned into a local thermal wave emitter. Quantitative evaluation of hidden damages was accomplished by estimating independently both the area and the depth extension of the buried flaws, while x-ray 3D computed tomography was used as reference for sizing accuracy assessment. To retrieve flaw's area, a simple yet effective histogram-based phase image segmentation algorithm with automatic pixels classification has been developed. A clear correlation was found between the thermal (phase) signature measured by the infrared camera on the target surface and the actual mean cross-section area of the flaw. Due to the very fast cycle time (<30 s/part), the method could potentially be applied for 100% quality control of casting components.

Uncertainty Analysis for the Evaluation of a Passive Runway Arresting System

NASA Technical Reports Server (NTRS)

Deloach, Richard; Marlowe, Jill M.; Yager, Thomas J.

2009-01-01

This paper considers the stopping distance of an aircraft involved in a runway overrun incident when the runway has been provided with an extension comprised of a material engineered to induce high levels of rolling friction and drag. A formula for stopping distance is derived that is shown to be the product of a known formula for the case of friction without drag, and a dimensionless constant between 0 and 1 that quantifies the further reduction in stopping distance when drag is introduced. This additional quantity, identified as the Drag Reduction Factor, D, is shown to depend on the ratio of drag force to friction force experienced by the aircraft as it enters the overrun area. The specific functional form of D is shown to depend on how drag varies with speed. A detailed uncertainty analysis is presented which reveals how the uncertainty in estimates of stopping distance are influenced by experimental error in the force measurements that are acquired in a typical evaluation experiment conducted to assess candidate overrun materials.

Antibacterial Potential of 2.5% Sodium Hypochlorite in Distinct Irrigation Protocols on Enterococcus faecalis Biofilm.

PubMed

Alves, Denise Ramos Silveira; Cunha, Rodrigo Sanches; da Silveira Bueno, Carlos Eduardo; de Alencar, Ana Helena Gonçalves; de Araújo Estrela, Cyntia Rodrigues; dos Santos, Tatiane Oliveira; Estrela, Carlos

2015-05-01

The aim of this study was to evaluate the effect of irrigation methods on antibacterial potential of 2.5% NaOCl on Enterococcus faecalis biofilm. Enterococcus faecalis biofilms were prepared during 60 days on 48 human root canals and randomized into control and experimental groups using positive and negative pressure irrigation. Bacterial growth was analyzed using turbidity of culture medium followed by UV spectrophotometry, and scanning electron microscopy (SEM) analyses were performed. Mean and standard deviations were used for evaluate the mean optical densities associated to the number of bacteria present culture, and Scheirer-Ray-Hare (an extension of the Kruskal-Wallis test) and Tamhane test to analyze the SEM images in the groups and thirds. Significance was set at 5%. Enterococcus faecalis was still present after root canal cleaning regardless of irrigation methods or bacterial identification methods. Positive and negative pressure irrigation protocols using 2.5% NaOCl show a similar capacity to reduce E. faecalis in infected root canals.

Use and optimization of a dual-flowrate loading strategy to maximize throughput in protein-a affinity chromatography.

PubMed

Ghose, Sanchayita; Nagrath, Deepak; Hubbard, Brian; Brooks, Clayton; Cramer, Steven M

2004-01-01

The effect of an alternate strategy employing two different flowrates during loading was explored as a means of increasing system productivity in Protein-A chromatography. The effect of such a loading strategy was evaluated using a chromatographic model that was able to accurately predict experimental breakthrough curves for this Protein-A system. A gradient-based optimization routine is carried out to establish the optimal loading conditions (initial and final flowrates and switching time). The two-step loading strategy (using a higher flowrate during the initial stages followed by a lower flowrate) was evaluated for an Fc-fusion protein and was found to result in significant improvements in process throughput. In an extension of this optimization routine, dynamic loading capacity and productivity were simultaneously optimized using a weighted objective function, and this result was compared to that obtained with the single flowrate. Again, the dual-flowrate strategy was found to be superior.

Correlation, evaluation, and extension of linearized theories for tire motion and wheel shimmy

NASA Technical Reports Server (NTRS)

Smiley, Robert F

1957-01-01

An evaluation is made of the existing theories of a linearized tire motion and wheel shimmy. It is demonstrated that most of the previously published theories represent varying degrees of approximation to a summary theory developed in this report which is a minor modification of the basic theory of Von Schlippe and Dietrich. In most cases where strong differences exist between the previously published theories and summary theory, the previously published theories are shown to possess certain deficiencies. A series of systematic approximations to the summary theory is developed for the treatment of problems too simple to merit the use of the complete summary theory, and procedures are discussed for applying the summary theory and its systematic approximations to the shimmy of more complex landing-gear structures than have previously been considered. Comparisons of the existing experimental data with the predictions of the summary theory and the systematic approximations provide a fair substantiation of the more detailed approximate theories.

Mid-career faculty development in academic medicine: How does it impact faculty and institutional vitality?

PubMed

Campion, MaryAnn W; Bhasin, Robina M; Beaudette, Donald J; Shann, Mary H; Benjamin, Emelia J

2016-09-01

Faculty vitality is integral to the advancement of higher education. Strengthening vitality is particularly important for mid-career faculty, who represent the largest and most dissatisfied segment. The demands of academic medicine appear to be another factor that may put faculty at risk of attrition. To address these issues, we initiated a ten-month mid-career faculty development program. A mixed-methods quasi-experimental design was used to evaluate the program's impact on faculty and institutional vitality. Pre/post surveys compared participants with a matched reference group. Quantitative data were augmented by interviews and focus groups with multiple stakeholders. At the program's conclusion, participants showed statistically significant gains in knowledge, skills, attitudes, and connectivity when compared to the referents. Given that mid-career faculty development in academic medicine has not been extensively studied, our evaluation provides a useful perspective to guide future initiatives aimed at enhancing the vitality and leadership capacity of mid-career faculty.

76 FR 2674 - Proposed Waiver and Extension of Project Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... the project. Additionally, PIRCs conducting experimental design studies experienced logistical challenges associated with establishing treatment and control groups. An additional year of funding would...

A soft wearable robot for the shoulder: Design, characterization, and preliminary testing.

PubMed

O'Neill, Ciaran T; Phipps, Nathan S; Cappello, Leonardo; Paganoni, Sabrina; Walsh, Conor J

2017-07-01

In this paper, we present a soft wearable robot for the shoulder which has the potential to assist individuals suffering from a range of neuromuscular conditions affecting the shoulder to perform activities of daily living. This wearable robot combines two types of soft textile pneumatic actuators which were custom developed for this particular application to support the upper arm through shoulder abduction and horizontal flexion/extension. The advantage of a textile-based approach is that the robot can be lightweight, low-profile, comfortable and non-restrictive to the wearer, and easy to don like an item of clothing. The actuator's ability to fold flat when not in use allows the robot to be almost invisible under clothing, potentially allowing the user to avoid any stigma associated with using assistive devices in public. To abduct the arm, a textilebased pneumatic actuator was developed to fit within the axilla to push the arm upwards, while a pair of smaller actuators pivot the abduction actuator to allow for horizontal extension and flexion. The individual textile actuators were experimentally evaluated before being integrated into a wearable garment. Human subject testing was performed to evaluate the ability of the robot to assist the arm by monitoring changes in biological muscle activity when comparing the robot powered on and off. Preliminary results show large reductions in muscular effort in targeted muscles, demonstrating the feasibility and promise of such a soft wearable robot for the shoulder.

A method for modifying two-dimensional adaptive wind-tunnel walls including analytical and experimental verification

NASA Technical Reports Server (NTRS)

Everhart, J. L.

1983-01-01

The theoretical development of a simple and consistent method for removing the interference in adaptive-wall wind tunnels is reported. A Cauchy integral formulation of the velocities in an imaginary infinite extension of the real wind-tunnel flow is obtained and evaluated on a closed contour dividing the real and imaginary flow. The contour consists of the upper and lower effective wind-tunnel walls (wall plus boundary-layer displacement thickness) and upstream and downstream boundaries perpendicular to the axial tunnel flow. The resulting integral expressions for the streamwise and normal perturbation velocities on the contour are integrated by assuming a linear variation of the velocities between data-measurement stations along the contour. In an iterative process, the velocity components calculated on the upper and lower boundaries are then used to correct the shape of the wall to remove the interference. Convergence of the technique is shown numerically for the cases of a circular cylinder and a lifting and nonlifting NACA 0012 airfoil in incompressible flow. Experimental convergence at a transonic Mach number is demonstrated by using an NACA 0012 airfoil at zero lift.

Static tests of excess ground attenuation at Wallops Flight Center

NASA Astrophysics Data System (ADS)

Sutherland, L. C.; Brown, R.

1981-06-01

An extensive experimental measurement program which evaluated the attenuation of sound for close to horizontal propagation over the ground was designed to replicate, under static conditions, results of the flight measurements carried out earlier by NASA at the same site (Wallops Flight Center). The program consisted of a total of 41 measurement runs of attenuation, in excess of spreading and air absorption losses, for one third octave bands over a frequency range of 50 to 4000 Hz. Each run consisted of measurements at 10 locations up to 675 m, from a source located at nominal elevations of 2.5, or 10 m over either a grassy surface or an adjacent asphalt concrete runway surface. The tests provided a total of over 8100 measurements of attenuation under conditions of low wind speed averaging about 1 m/s and, for most of the tests, a slightly positive temperature gradient, averaging about 0.3 C/m from 1.2 to 7 m. The results of the measurements are expected to provide useful experimental background for the further development of prediction models of near grazing incidence sound propagation losses.

Fluid displacement during droplet formation at microfluidic flow-focusing junctions.

PubMed

Huang, Haishui; He, Xiaoming

2015-11-07

Microdroplets and microcapsules have been widely produced using microfluidic flow-focusing junctions for biomedical and chemical applications. However, the multiphase microfluidic flow at the flow-focusing junction has not been well investigated. In this study, the displacement of two (core and shell) aqueous fluids that disperse into droplets altogether in a carrier oil emulsion was investigated both numerically and experimentally. It was found that extensive displacement of the two aqueous fluids within the droplet during its formation could occur as a result of the shear effect of the carrier fluid and the capillary effect of interfacial tension. We further identified that the two mechanisms of fluid displacement can be evaluated by two dimensionless parameters. The quantitative relationship between the degree of fluid displacement and these two dimensionless parameters was determined experimentally. Finally, we demonstrated that the degree of fluid displacement could be controlled to generate hydrogel microparticles of different morphologies using planar or nonplanar flow-focusing junctions. These findings should provide useful guidance to the microfluidic production of microscale droplets or capsules for various biomedical and chemical applications.

Static tests of excess ground attenuation at Wallops Flight Center

NASA Technical Reports Server (NTRS)

Sutherland, L. C.; Brown, R.

1981-01-01

An extensive experimental measurement program which evaluated the attenuation of sound for close to horizontal propagation over the ground was designed to replicate, under static conditions, results of the flight measurements carried out earlier by NASA at the same site (Wallops Flight Center). The program consisted of a total of 41 measurement runs of attenuation, in excess of spreading and air absorption losses, for one third octave bands over a frequency range of 50 to 4000 Hz. Each run consisted of measurements at 10 locations up to 675 m, from a source located at nominal elevations of 2.5, or 10 m over either a grassy surface or an adjacent asphalt concrete runway surface. The tests provided a total of over 8100 measurements of attenuation under conditions of low wind speed averaging about 1 m/s and, for most of the tests, a slightly positive temperature gradient, averaging about 0.3 C/m from 1.2 to 7 m. The results of the measurements are expected to provide useful experimental background for the further development of prediction models of near grazing incidence sound propagation losses.

RC beams shear-strengthened with fabric-reinforced-cementitious-matrix (FRCM) composite

NASA Astrophysics Data System (ADS)

Loreto, Giovanni; Babaeidarabad, Saman; Leardini, Lorenzo; Nanni, Antonio

2015-12-01

The interest in retrofit/rehabilitation of existing concrete structures has increased due to degradation and/or introduction of more stringent design requirements. Among the externally-bonded strengthening systems fiber-reinforced polymers is the most widely known technology. Despite its effectiveness as a material system, the presence of an organic binder has some drawbacks that could be addressed by using in its place a cementitious binder as in fabric-reinforced cementitious matrix (FRCM) systems. The purpose of this paper is to evaluate the behavior of reinforced concrete (RC) beams strengthened in shear with U-wraps made of FRCM. An extensive experimental program was undertaken in order to understand and characterize this composite when used as a strengthening system. The laboratory results demonstrate the technical viability of FRCM for shear strengthening of RC beams. Based on the experimental and analytical results, FRCM increases shear strength but not proportionally to the number of fabric plies installed. On the other hand, FRCM failure modes are related with a high consistency to the amount of external reinforcement applied. Design considerations based on the algorithms proposed by ACI guidelines are also provided.

Kernel Regression Estimation of Fiber Orientation Mixtures in Diffusion MRI

PubMed Central

Cabeen, Ryan P.; Bastin, Mark E.; Laidlaw, David H.

2016-01-01

We present and evaluate a method for kernel regression estimation of fiber orientations and associated volume fractions for diffusion MR tractography and population-based atlas construction in clinical imaging studies of brain white matter. This is a model-based image processing technique in which representative fiber models are estimated from collections of component fiber models in model-valued image data. This extends prior work in nonparametric image processing and multi-compartment processing to provide computational tools for image interpolation, smoothing, and fusion with fiber orientation mixtures. In contrast to related work on multi-compartment processing, this approach is based on directional measures of divergence and includes data-adaptive extensions for model selection and bilateral filtering. This is useful for reconstructing complex anatomical features in clinical datasets analyzed with the ball-and-sticks model, and our framework’s data-adaptive extensions are potentially useful for general multi-compartment image processing. We experimentally evaluate our approach with both synthetic data from computational phantoms and in vivo clinical data from human subjects. With synthetic data experiments, we evaluate performance based on errors in fiber orientation, volume fraction, compartment count, and tractography-based connectivity. With in vivo data experiments, we first show improved scan-rescan reproducibility and reliability of quantitative fiber bundle metrics, including mean length, volume, streamline count, and mean volume fraction. We then demonstrate the creation of a multi-fiber tractography atlas from a population of 80 human subjects. In comparison to single tensor atlasing, our multi-fiber atlas shows more complete features of known fiber bundles and includes reconstructions of the lateral projections of the corpus callosum and complex fronto-parietal connections of the superior longitudinal fasciculus I, II, and III. PMID:26691524

Research applications for an Object and Action Naming Battery to assess naming skills in adult Spanish-English bilingual speakers.

PubMed

Edmonds, Lisa A; Donovan, Neila J

2014-06-01

Virtually no valid materials are available to evaluate confrontation naming in Spanish-English bilingual adults in the U.S. In a recent study, a large group of young Spanish-English bilingual adults were evaluated on An Object and Action Naming Battery (Edmonds & Donovan in Journal of Speech, Language, and Hearing Research 55:359-381, 2012). Rasch analyses of the responses resulted in evidence for the content and construct validity of the retained items. However, the scope of that study did not allow for extensive examination of individual item characteristics, group analyses of participants, or the provision of testing and scoring materials or raw data, thereby limiting the ability of researchers to administer the test to Spanish-English bilinguals and to score the items with confidence. In this study, we present the in-depth information described above on the basis of further analyses, including (1) online searchable spreadsheets with extensive empirical (e.g., accuracy and name agreeability) and psycholinguistic item statistics; (2) answer sheets and instructions for scoring and interpreting the responses to the Rasch items; (3) tables of alternative correct responses for English and Spanish; (4) ability strata determined for all naming conditions (English and Spanish nouns and verbs); and (5) comparisons of accuracy across proficiency groups (i.e., Spanish dominant, English dominant, and balanced). These data indicate that the Rasch items from An Object and Action Naming Battery are valid and sensitive for the evaluation of naming in young Spanish-English bilingual adults. Additional information based on participant responses for all of the items on the battery can provide researchers with valuable information to aid in stimulus development and response interpretation for experimental studies in this population.

Bench-Scale Trace Contaminant Testing of SA9T at Ambient and Reduced Pressure Conditions

NASA Technical Reports Server (NTRS)

Broerman, Craig; Sweterlitsch, Jeff

2011-01-01

A principal concern for air revitalization technology in a closed loop system is the capability to control carbon dioxide (CO2) and humidity (H2O). An amine based sorbent technology, SA9T, has been evaluated for use in this application and several programs are evaluating it for use in both cabin and space suit applications. While the CO2 and H2O performance of the sorbent has been tested extensively, the question of how trace contaminants impact performance requires further evaluation. This paper presents experimental results of bench-scale SA9T testing that was performed under a variety of test conditions and with several different trace contaminants. Tests were conducted to determine if the capacity of the SA9T media to sufficiently remove CO2 and H2O is compromised after exposure to a fully saturated trace contaminant at ambient conditions. Tests also were conducted to evaluate the performance of SA9T at ambient conditions in a continuous 30-day test with a mixed trace contaminant stream. In addition, testing also evaluated the impact of CO2 and H2O removal performance at suit loop pressures (29.6 KPa/4.3 psia) during cyclic operation with a constant inlet contaminant load.

Experimental Estimation of Mutation Rates in a Wheat Population With a Gene Genealogy Approach

PubMed Central

Raquin, Anne-Laure; Depaulis, Frantz; Lambert, Amaury; Galic, Nathalie; Brabant, Philippe; Goldringer, Isabelle

2008-01-01

Microsatellite markers are extensively used to evaluate genetic diversity in natural or experimental evolving populations. Their high degree of polymorphism reflects their high mutation rates. Estimates of the mutation rates are therefore necessary when characterizing diversity in populations. As a complement to the classical experimental designs, we propose to use experimental populations, where the initial state is entirely known and some intermediate states have been thoroughly surveyed, thus providing a short timescale estimation together with a large number of cumulated meioses. In this article, we derived four original gene genealogy-based methods to assess mutation rates with limited bias due to relevant model assumptions incorporating the initial state, the number of new alleles, and the genetic effective population size. We studied the evolution of genetic diversity at 21 microsatellite markers, after 15 generations in an experimental wheat population. Compared to the parents, 23 new alleles were found in generation 15 at 9 of the 21 loci studied. We provide evidence that they arose by mutation. Corresponding estimates of the mutation rates ranged from 0 to 4.97 × 10−3 per generation (i.e., year). Sequences of several alleles revealed that length polymorphism was only due to variation in the core of the microsatellite. Among different microsatellite characteristics, both the motif repeat number and an independent estimation of the Nei diversity were correlated with the novel diversity. Despite a reduced genetic effective size, global diversity at microsatellite markers increased in this population, suggesting that microsatellite diversity should be used with caution as an indicator in biodiversity conservation issues. PMID:18689900

Experimental estimation of mutation rates in a wheat population with a gene genealogy approach.

PubMed

Raquin, Anne-Laure; Depaulis, Frantz; Lambert, Amaury; Galic, Nathalie; Brabant, Philippe; Goldringer, Isabelle

2008-08-01

Microsatellite markers are extensively used to evaluate genetic diversity in natural or experimental evolving populations. Their high degree of polymorphism reflects their high mutation rates. Estimates of the mutation rates are therefore necessary when characterizing diversity in populations. As a complement to the classical experimental designs, we propose to use experimental populations, where the initial state is entirely known and some intermediate states have been thoroughly surveyed, thus providing a short timescale estimation together with a large number of cumulated meioses. In this article, we derived four original gene genealogy-based methods to assess mutation rates with limited bias due to relevant model assumptions incorporating the initial state, the number of new alleles, and the genetic effective population size. We studied the evolution of genetic diversity at 21 microsatellite markers, after 15 generations in an experimental wheat population. Compared to the parents, 23 new alleles were found in generation 15 at 9 of the 21 loci studied. We provide evidence that they arose by mutation. Corresponding estimates of the mutation rates ranged from 0 to 4.97 x 10(-3) per generation (i.e., year). Sequences of several alleles revealed that length polymorphism was only due to variation in the core of the microsatellite. Among different microsatellite characteristics, both the motif repeat number and an independent estimation of the Nei diversity were correlated with the novel diversity. Despite a reduced genetic effective size, global diversity at microsatellite markers increased in this population, suggesting that microsatellite diversity should be used with caution as an indicator in biodiversity conservation issues.

Dental extraction following zoledronate, induces osteonecrosis in rat´s jaw

PubMed Central

Gómez-Clavel, José-Francisco; Gaitán-Cepeda, Luis-Alberto

2017-01-01

Background Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks. Previous attempts to establish an animal model have not sufficiently considered disease features. Our aim was to establish an inexpensive and replicable animal model that develops BRONJ in a short time. Material and Methods Thirty-two male Wistar rats were randomly divided into two groups: control and experimental. In the experimental group, we administered 0.06mg/kg intraperitoneal dose of zoledronic acid (ZA) 7 and 14 days prior to maxillary second molar extraction. At two, four and six weeks after tooth extraction, the animals were euthanized, and we dissected the maxilla following histological procedures. We stained serial slides with hematoxylin and eosin and Masson’s trichrome. The samples were harvested for macroscopic, radiologic and histological evaluation of bone changes. Results At two weeks postextraction, we observed exposed necrotic bone in dental socket areas in experimental groups. Radiological analysis revealed osteolytic lesions accompanied by extensive destruction and sequestrum formation in the same group. Histological examination confirmed the absence of necrotic bone in control groups in contrast with the experimental groups. The percentage of empty lacunae and the number of osteoclasts and the necrotic bone area were significantly increased (p<0.05) in the experimental groups. Conclusions The animal model using ZA administration to prior dental extraction successfully mimicked human BRONJ lesions. Also, the model was easily replicated, inexpensive and showed different features than other previous BRONJ models. Key words:Bisphosphonates, osteonecrosis, dental extractions, animal model, BRONJ. PMID:28160593

Performance of a RBCC Engine in Rocket-Operation

NASA Astrophysics Data System (ADS)

Tomioka, Sadatake; Kubo, Takahiro; Noboru Sakuranaka; Tani, Koichiro

Combination of a scramjet (supersonic combustion ramjet) flow-pass with embedded rocket engines (the combined system termed as Rocket-based Combined Cycle engine) are expected to be the most effective propulsion system for space launch vehicles. Either SSTO (Single Stage To Orbit) system or TSTO (Two Stage To Orbit) system with separation at high altitude needs final stage acceleration in space, so that the RBCC (Rocket Based Combined Cycle) engine should be operated as rocket engines. Performance of the scramjet combustor as the extension to the rocket nozzle, was experimentally evaluated by injecting inert gas at various pressure through the embedded rocket chamber while the whole sub-scaled model was placed in a low pressure chamber connected to an air-driven ejector system. The results showed that the thrust coefficient was about 1.2, the low value being found to mainly due to the friction force on the scramjet combustor wall, while blocking the scramjet flow pass’s opening to increase nozzle extension thrust surface, was found to have little effects on the thrust performance. The combustor was shortened to reduce the friction loss, however, degree of reduction was limited as friction decreased rapidly with distance from the onset of the scramjet combustor.

Design and control of the MINDWALKER exoskeleton.

PubMed

Wang, Shiqian; Wang, Letian; Meijneke, Cory; van Asseldonk, Edwin; Hoellinger, Thomas; Cheron, Guy; Ivanenko, Yuri; La Scaleia, Valentina; Sylos-Labini, Francesca; Molinari, Marco; Tamburella, Federica; Pisotta, Iolanda; Thorsteinsson, Freygardur; Ilzkovitz, Michel; Gancet, Jeremi; Nevatia, Yashodhan; Hauffe, Ralf; Zanow, Frank; van der Kooij, Herman

2015-03-01

Powered exoskeletons can empower paraplegics to stand and walk. Actively controlled hip ab/adduction (HAA) is needed for weight shift and for lateral foot placement to support dynamic balance control and to counteract disturbances in the frontal plane. Here, we describe the design, control, and preliminary evaluation of a novel exoskeleton, MINDWALKER. Besides powered hip flexion/extension and knee flexion/extension, it also has powered HAA. Each of the powered joints has a series elastic actuator, which can deliver 100 Nm torque and 1 kW power. A finite-state machine based controller provides gait assistance in both the sagittal and frontal planes. State transitions, such as stepping, can be triggered by the displacement of the Center of Mass (CoM). A novel step-width adaptation algorithm was proposed to stabilize lateral balance. We tested this exoskeleton on both healthy subjects and paraplegics. Experimental results showed that all users could successfully trigger steps by CoM displacement. The step-width adaptation algorithm could actively counteract disturbances, such as pushes. With the current implementations, stable walking without crutches has been achieved for healthy subjects but not yet for SCI paraplegics. More research and development is needed to improve the gait stability.

Hidden contributions of the enamel rods on the fracture resistance of human teeth

PubMed Central

Yahyazadehfar, M.; Bajaj, Devendra; Arola, Dwayne D.

2013-01-01

The enamel of human teeth is generally regarded as a brittle material with low fracture toughness. Consequently, the contributions of this tissue in resisting tooth fracture and the importance of its complex microstructure have been largely overlooked. In this study an experimental evaluation of the crack growth resistance of human enamel was conducted to characterize the role of rod (i.e. prism) orientation and degree of decussation on the fracture behavior of this tissue. Incremental crack growth was achieved in-plane, with the rods in directions longitudinal or transverse to their axes. Results showed that the fracture resistance of enamel is both inhomogeneous and spatially anisotropic. Cracks extending transverse to the rods in the outer enamel undergo a lower rise in toughness with extension, and achieve significantly lower fracture resistance than in the longitudinal direction. Though cracks initiating at the surface of teeth may begin extension towards the dentin–enamel junction, they are deflected by the decussated rods and continue growth about the tooth’s periphery, transverse to the rods in the outer enamel. This process facilitates dissipation of fracture energy and averts cracks from extending towards the dentin and vital pulp. PMID:23022547

Model identification and vision-based H∞ position control of 6-DoF cable-driven parallel robots

NASA Astrophysics Data System (ADS)

Chellal, R.; Cuvillon, L.; Laroche, E.

2017-04-01

This paper presents methodologies for the identification and control of 6-degrees of freedom (6-DoF) cable-driven parallel robots (CDPRs). First a two-step identification methodology is proposed to accurately estimate the kinematic parameters independently and prior to the dynamic parameters of a physics-based model of CDPRs. Second, an original control scheme is developed, including a vision-based position controller tuned with the H∞ methodology and a cable tension distribution algorithm. The position is controlled in the operational space, making use of the end-effector pose measured by a motion-tracking system. A four-block H∞ design scheme with adjusted weighting filters ensures good trajectory tracking and disturbance rejection properties for the CDPR system, which is a nonlinear-coupled MIMO system with constrained states. The tension management algorithm generates control signals that maintain the cables under feasible tensions. The paper makes an extensive review of the available methods and presents an extension of one of them. The presented methodologies are evaluated by simulations and experimentally on a redundant 6-DoF INCA 6D CDPR with eight cables, equipped with a motion-tracking system.

Ulcerative proctitis: an update on the pharmacotherapy and management.

PubMed

Gecse, Krisztina B; Lakatos, Peter L

2014-08-01

Ulcerative colitis (UC) presents as proctitis in approximately a quarter of the patients. It may progress into left-sided or extensive colitis in up to 50% of cases upon long-term follow-up. Currently available data on ulcerative proctitis are summarized and critically reviewed. Extensive literature search (MEDLINE) was performed to identify relevant articles up to March 2014. The short-term goal of the treatment in UC is to induce remission, whereas long-term goals are to maintain remission and prevent disease progression. Topically administered 5-aminosalicylates (5-ASA) and corticosteroids are effective in the treatment of proctitis, although they seem to be underused in everyday practice. Locally administered 5-ASA preparations are more effective than oral compounds. The combination of topical and oral 5-ASA and steroids should be considered for escalation of treatment. Refractory patients should be re-evaluated to exclude for compliance failures, infections or proximal disease extent. True refractory or steroid-dependent patients may require immunomodulators or biological therapy. Alternative medicine can be used complementarily, while experimental approaches are reserved for patients failing conventional medication. Proctocolectomy may be the last resort of treatment. Upon long-term, 5-ASA maintenance treatment is indicated in all UC cases to prevent relapse and disease progression.

Critical stresses for extension of filament-bridged matrix cracks in ceramic-matrix composites: An assessment with a model composite with tailored interfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Danchaivijit, S.; Shetty, D.K.; Eldridge, J.

Matrix cracking was studied in a model unidirectional composite of SiC filaments in an epoxy-bonded alumina matrix. The residual clamping stress on the filaments due to the shrinkage of the epoxy was moderated with the addition of the alumina filler, and the filament surface was coated with a releasing agent to produce unbonded frictional interfaces. Uniaxial tension specimens with controlled through-cracks with bridging filaments were fabricated by a two-step casting technique. Critical stresses for extension of the filament-bridged cracks of various lengths were measured in uniaxial tension using a high-sensitivity extensometer. The measured crack-length dependence of the critical stress wasmore » in good agreement with the prediction of a stress-intensity analysis that employed a new force-displacement law for the bridging filaments. The analysis required independent experimental evaluation of the matrix fracture toughness, the interfacial sliding friction stress, and the residual tension in the matrix. The matrix-cracking stress for the test specimens without the deliberately introduced cracks was significantly higher than the steady-state cracking stress measured for the long, filament-bridged cracks.« less

Evaluating the utility of two gestural discomfort evaluation methods

PubMed Central

Son, Minseok; Jung, Jaemoon; Park, Woojin

2017-01-01

Evaluating physical discomfort of designed gestures is important for creating safe and usable gesture-based interaction systems; yet, gestural discomfort evaluation has not been extensively studied in HCI, and few evaluation methods seem currently available whose utility has been experimentally confirmed. To address this, this study empirically demonstrated the utility of the subjective rating method after a small number of gesture repetitions (a maximum of four repetitions) in evaluating designed gestures in terms of physical discomfort resulting from prolonged, repetitive gesture use. The subjective rating method has been widely used in previous gesture studies but without empirical evidence on its utility. This study also proposed a gesture discomfort evaluation method based on an existing ergonomics posture evaluation tool (Rapid Upper Limb Assessment) and demonstrated its utility in evaluating designed gestures in terms of physical discomfort resulting from prolonged, repetitive gesture use. Rapid Upper Limb Assessment is an ergonomics postural analysis tool that quantifies the work-related musculoskeletal disorders risks for manual tasks, and has been hypothesized to be capable of correctly determining discomfort resulting from prolonged, repetitive gesture use. The two methods were evaluated through comparisons against a baseline method involving discomfort rating after actual prolonged, repetitive gesture use. Correlation analyses indicated that both methods were in good agreement with the baseline. The methods proposed in this study seem useful for predicting discomfort resulting from prolonged, repetitive gesture use, and are expected to help interaction designers create safe and usable gesture-based interaction systems. PMID:28423016

Finishing bacterial genome assemblies with Mix.

PubMed

Soueidan, Hayssam; Maurier, Florence; Groppi, Alexis; Sirand-Pugnet, Pascal; Tardy, Florence; Citti, Christine; Dupuy, Virginie; Nikolski, Macha

2013-01-01

Among challenges that hamper reaping the benefits of genome assembly are both unfinished assemblies and the ensuing experimental costs. First, numerous software solutions for genome de novo assembly are available, each having its advantages and drawbacks, without clear guidelines as to how to choose among them. Second, these solutions produce draft assemblies that often require a resource intensive finishing phase. In this paper we address these two aspects by developing Mix , a tool that mixes two or more draft assemblies, without relying on a reference genome and having the goal to reduce contig fragmentation and thus speed-up genome finishing. The proposed algorithm builds an extension graph where vertices represent extremities of contigs and edges represent existing alignments between these extremities. These alignment edges are used for contig extension. The resulting output assembly corresponds to a set of paths in the extension graph that maximizes the cumulative contig length. We evaluate the performance of Mix on bacterial NGS data from the GAGE-B study and apply it to newly sequenced Mycoplasma genomes. Resulting final assemblies demonstrate a significant improvement in the overall assembly quality. In particular, Mix is consistent by providing better overall quality results even when the choice is guided solely by standard assembly statistics, as is the case for de novo projects. Mix is implemented in Python and is available at https://github.com/cbib/MIX, novel data for our Mycoplasma study is available at http://services.cbib.u-bordeaux2.fr/mix/.

Nondestructive analysis and development

NASA Technical Reports Server (NTRS)

Moslehy, Faissal A.

1993-01-01

This final report summarizes the achievements of project #4 of the NASA/UCF Cooperative Agreement from January 1990 to December 1992. The objectives of this project are to review NASA's NDE program at Kennedy Space Center (KSC) and recommend means for enhancing the present testing capabilities through the use of improved or new technologies. During the period of the project, extensive development of a reliable nondestructive, non-contact vibration technique to determine and quantify the bond condition of the thermal protection system (TPS) tiles of the Space Shuttle Orbiter was undertaken. Experimental modal analysis (EMA) is used as a non-destructive technique for the evaluation of Space Shuttle thermal protection system (TPS) tile bond integrity. Finite element (FE) models for tile systems were developed and were used to generate their vibration characteristics (i.e. natural frequencies and mode shapes). Various TPS tile assembly configurations as well as different bond conditions were analyzed. Results of finite element analyses demonstrated a drop in natural frequencies and a change in mode shapes which correlate with both size and location of disbond. Results of experimental testing of tile panels correlated with FE results and demonstrated the feasibility of EMA as a viable technique for tile bond verification. Finally, testing performed on the Space Shuttle Columbia using a laser doppler velocimeter demonstrated the application of EMA, when combined with FE modeling, as a non-contact, non-destructive bond evaluation technique.

Cheating and Anti-Cheating in Gossip-Based Protocol: An Experimental Investigation

NASA Astrophysics Data System (ADS)

Xiao, Xin; Shi, Yuanchun; Tang, Yun; Zhang, Nan

During recent years, there has been a rapid growth in deployment of gossip-based protocol in many multicast applications. In a typical gossip-based protocol, each node acts as dual roles of receiver and sender, independently exchanging data with its neighbors to facilitate scalability and resilience. However, most of previous work in this literature seldom considered cheating issue of end users, which is also very important in face of the fact that the mutual cooperation inherently determines overall system performance. In this paper, we investigate the dishonest behaviors in decentralized gossip-based protocol through extensive experimental study. Our original contributions come in two-fold: In the first part of cheating study, we analytically discuss two typical cheating strategies, that is, intentionally increasing subscription requests and untruthfully calculating forwarding probability, and further evaluate their negative impacts. The results indicate that more attention should be paid to defending cheating behaviors in gossip-based protocol. In the second part of anti-cheating study, we propose a receiver-driven measurement mechanism, which evaluates individual forwarding traffic from the perspective of receivers and thus identifies cheating nodes with high incoming/outgoing ratio. Furthermore, we extend our mechanism by introducing reliable factor to further improve its accuracy. The experiments under various conditions show that it performs quite well in case of serious cheating and achieves considerable performance in other cases.

Scaffold microstructure effects on functional and mechanical performance: Integration of theoretical and experimental approaches for bone tissue engineering applications.

PubMed

Cavo, Marta; Scaglione, Silvia

2016-11-01

The really nontrivial goal of tissue engineering is combining all scaffold micro-architectural features, affecting both fluid-dynamical and mechanical performance, to obtain a fully functional implant. In this work we identified an optimal geometrical pattern for bone tissue engineering applications, best balancing several graft needs which correspond to competing design goals. In particular, we investigated the occurred changes in graft behavior by varying pore size (300μm, 600μm, 900μm), interpore distance (equal to pore size or 300μm fixed) and pores interconnection (absent, 45°-oriented, 90°-oriented). Mathematical considerations and Computational Fluid Dynamics (CFD) tools, here combined in a complete theoretical model, were carried out to this aim. Poly-lactic acid (PLA) based samples were realized by 3D printing, basing on the modeled architectures. A collagen (COL) coating was also realized on grafts surface and the interaction between PLA and COL, besides the protein contribution to graft bioactivity, was evaluated. Scaffolds were extensively characterized; human articular cells were used to test their biocompatibility and to evaluate the theoretical model predictions. Grafts fulfilled both the chemical and physical requirements. Finally, a good agreement was found between the theoretical model predictions and the experimental data, making these prototypes good candidates for bone graft replacements. Copyright © 2016 Elsevier B.V. All rights reserved.

Mechanics of fiber reinforced materials

NASA Astrophysics Data System (ADS)

Sun, Huiyu

This dissertation is dedicated to mechanics of fiber reinforced materials and the woven reinforcement and composed of four parts of research: analytical characterization of the interfaces in laminated composites; micromechanics of braided composites; shear deformation, and Poisson's ratios of woven fabric reinforcements. A new approach to evaluate the mechanical characteristics of interfaces between composite laminae based on a modified laminate theory is proposed. By including an interface as a special lamina termed the "bonding-layer" in the analysis, the mechanical properties of the interfaces are obtained. A numerical illustration is given. For micro-mechanical properties of three-dimensionally braided composite materials, a new method via homogenization theory and incompatible multivariable FEM is developed. Results from the hybrid stress element approach compare more favorably with the experimental data than other existing numerical methods widely used. To evaluate the shearing properties for woven fabrics, a new mechanical model is proposed during the initial slip region. Analytical results show that this model provides better agreement with the experiments for both the initial shear modulus and the slipping angle than the existing models. Finally, another mechanical model for a woven fabric made of extensible yarns is employed to calculate the fabric Poisson's ratios. Theoretical results are compared with the available experimental data. A thorough examination on the influences of various mechanical properties of yarns and structural parameters of fabrics on the Poisson's ratios of a woven fabric is given at the end.

Exploring the Impact of Professional Development and Professional Practice on School Leaders' Self-Efficacy: A Quasi-Experimental Study

ERIC Educational Resources Information Center

Petridou, Alexandra; Nicolaidou, Maria; Karagiorgi, Yiasemina

2017-01-01

Self-efficacy is extensively discussed within social cognitive theory. This study aimed to explore the impact of professional development and practice on school leaders' self-efficacy in Cyprus. A quasi-experimental design involving 2 groups of novice secondary deputy head teachers was employed. All participants practised leadership at the time,…

What Can We Learn from Toddlers about Categorical Perception of Color? Comments on Goldstein, Davidoff, and Roberson

ERIC Educational Resources Information Center

Franklin, Anna; Wright, Oliver; Davies, Ian R. L.

2009-01-01

We comment on Goldstein, Davidoff, and Roberson's replication and extension ("Journal of Experimental Child Psychology, 102", 219-238 [2009]) of our study of the effect of toddlers' color term knowledge on their categorical perception (CP) of color ("Journal of Experimental Child Psychology, 90", 114-141 [2005]). First, we discuss how best to…

Turning data into knowledge for over 50 years: USDA Forest Service research on the Penobscot Experimental Forest

Treesearch

Laura S. Kenefic; Paul E. Sendak; John C. Brissette

2006-01-01

Scientists from the Northeastern Research Station of the USDA Forest Service have been conducting long-term silvicultural research on the Penobscot Experimental Forest (PEF) in Maine since the early 1950s. The core experiment, which includes 10 replicated treatments, has generated an extensive dataset on forest response to both silvicultural treatments and exploitative...

Ensuring Data Quality in Extension Research and Evaluation Studies

ERIC Educational Resources Information Center

Radhakrishna, Rama; Tobin, Daniel; Brennan, Mark; Thomson, Joan

2012-01-01

This article presents a checklist as a guide for Extension professionals to use in research and evaluation studies they carry out. A total of 40 statements grouped under eight data quality components--relevance, objectivity, validity, reliability, integrity, generalizability, completeness, and utility--are identified to ensure that research…

Working with Our Publics. In-Service Education for Cooperative Extension. Module 2. The Extension Education Process.

ERIC Educational Resources Information Center

Mustian, R. David; And Others

This module is the second in an inservice education series for extension professionals that consists of seven independent training modules. It is an introduction to, and guided practice in, the premises, concepts, and processes of nonformal extension education--planning, designing and implementing, and evaluating and accounting for extension…

An ambient assisted living approach in designing domiciliary services combined with innovative technologies for patients with Alzheimer's disease: a case study.

PubMed

Cavallo, Filippo; Aquilano, Michela; Arvati, Marco

2015-02-01

Alzheimer's disease (AD) is one of the most disabling diseases to affect large numbers of elderly people worldwide. Because of the characteristics of this disease, patients with AD require daily assistance from service providers both in nursing homes and at home. Domiciliary assistance has been demonstrated to be cost effective and efficient in the first phase of the disease, helping to slow down the course of the illness, improve the quality of life and care, and extend independence for patients and caregivers. In this context, the aim of this work is to demonstrate the technical effectiveness and acceptability of an innovative domiciliary smart sensor system for providing domiciliary assistance to patients with AD which has been developed with an Ambient Assisted Living (AAL) approach. The design, development, testing, and evaluation of the innovative technological solution were performed by a multidisciplinary team. In all, 15 sociomedical operators and 14 patients with AD were directly involved in defining the end-users' needs and requirements, identifying design principles with acceptability and usability features and evaluating the technological solutions before and after the real experimentation. A modular technological system was produced to help caregivers continuously monitor the health status, safety, and daily activities of patients with AD. During the experimentation, the acceptability, utility, usability, and efficacy of this system were evaluated as quite positive. The experience described in this article demonstrated that AAL technologies are feasible and effective nowadays and can be actively used in assisting patients with AD in their homes. The extensive involvement of caregivers in the experimentation allowed to assess that there is, through the use of the technological system, a proven improvement in care performance and efficiency of care provision by both formal and informal caregivers and consequently an increase in the quality of life of patients, their relatives, and their caregivers. © The Author(s) 2014.

Incubation Temperature, But Not Pequi Oil Supplementation, Affects Methane Production, and the Ruminal Microbiota in a Rumen Simulation Technique (Rusitec) System.

PubMed

Duarte, Andrea C; Holman, Devin B; Alexander, Trevor W; Kiri, Kerstin; Breves, Gerhard; Chaves, Alexandre V

2017-01-01

Lipid supplementation is a promising strategy for methane mitigation in cattle and has been evaluated using several different lipid sources. However, limited studies have assessed the effect of temperature on methane emissions from cattle and changes in incubation temperature have also not been extensively evaluated. The aim of this study was to evaluate the combined effect of pequi oil (high in unsaturated fatty acids) and incubation temperature on fermentation characteristics and microbial communities using the rumen simulation technique. A completely randomized experiment was conducted over a 28-day period using a Rusitec system. The experiment was divided into four periods of 7 days each, the first of which was a 7-day adaptation period followed by three experimental periods. The two treatments consisted of a control diet (no pequi oil inclusion) and a diet supplemented with pequi oil (1.5 mL/day) which increased the dietary fat content to 6% (dry matter, DM-basis). Three fermenter vessels (i.e., replicates) were allocated to each treatment. In the first experimental period, the incubation temperature was maintained at 39°C, decreased to 35°C in the second experimental period and then increased again to 39°C in the third. Pequi oil was continuously supplemented during the experiment. Microbial communities were assessed using high-throughput sequencing of the archaeal and bacterial 16S rRNA gene. Methane production was reduced by 57% following a 4°C decrease in incubation temperature. Supplementation with pequi oil increased the dietary fat content to 6% (DM-basis) but did not affect methane production. Analysis of the microbiota revealed that decreasing incubation temperature to 35°C affected the archaeal and bacterial diversity and richness of liquid-associated microbes, but lipid supplementation did not change microbial diversity.

Mirror therapy for distal radial fractures: A pilot randomized controlled study.

PubMed

Bayon-Calatayud, Manuel; Benavente-Valdepeñas, Ana Maria; Del Prado Vazquez-Muñoz, Maria

2016-10-12

To investigate the efficacy of mirror therapy in reducing pain and disability in patients with distal radial fractures. Pilot randomized controlled study. Twenty-two patients with closed distal radial fracture. Patients were randomly assigned to experimental (= 11) or control (= 11) groups. Researchers were blinded to group allocation. Both groups received conventional physiotherapy. In addition, the experimental group had 15 sessions of mirror therapy (a daily session, 30 min). The control group received the same amount of conventional occupational therapy. Assessment was made from baseline to post-treatment. Pain was measured on a visual analogue scale (VAS). Active wrist extension and Quick-DASH (Disabilities of Arm, Shoulder and Hand) were used to assess functional recovery. Pain, disability, and range of motion improved for both groups after intervention. No significant post-treatment differences were found between groups in Quick-DASH (= 0.409), active wrist extension (= 0.191) and VAS scores (= 0.807). There was no significant difference in active wrist extension between groups. Mirror therapy was not superior to conventional occupational therapy in reducing pain and disability.

10 CFR 30.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... private institution, group, Government agency other than the Commission or the Department, except that the... experimentation; or (2) the extension of investigative findings and theories of a scientific or technical nature...

Single scattering from nonspherical Chebyshev particles: A compendium of calculations

NASA Technical Reports Server (NTRS)

Wiscombe, W. J.; Mugnai, A.

1986-01-01

A large set of exact calculations of the scattering from a class of nonspherical particles known as Chebyshev particles' has been performed. Phase function and degree of polarization in random orientation, and parallel and perpendicular intensities in fixed orientations, are plotted for a variety of particles shapes and sizes. The intention is to furnish a data base against which both experimental data, and the predictions of approximate methods, can be tested. The calculations are performed with the widely-used Extended Boundary Condition Method. An extensive discussion of this method is given, including much material that is not easily available elsewhere (especially the analysis of its convergence properties). An extensive review is also given of all extant methods for nonspherical scattering calculations, as well as of the available pool of experimental data.

Plasma gasification of municipal solid waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carter, G.W.; Tsangaris, A.V.

1995-12-31

Resorption Canada Limited (RCL) has conducted extensive operational testing with plasma technology in their plasma facility near Ottawa, Ontario, Canada to develop an environmentally friendly waste disposal process. Plasma technology, when utilized in a reactor vessel with the exclusion of oxygen, provides for the complete gasification of all combustibles in source materials with non-combustibles being converted to a non-hazardous slag. The energy and environmental characteristics of the plasma gasification of carbonaceous waste materials were studied over a period of eight years during which RCL completed extensive experimentation with MSW. A plasma processing system capable of processing 200--400 lbs/hr of MSWmore » was designed and built. The experimentation on MSW concentrated on establishing the optimum operating parameters and determining the energy and environmental characteristics at these operating parameters.« less

The landing flare: An analysis and flight-test investigation

NASA Technical Reports Server (NTRS)

Seckel, E.

1975-01-01

Results are given of an extensive investigation of conventional landing flares in general aviation type airplanes. A wide range of parameters influencing flare behavior are simulated in experimental landings in a variable-stability Navion. The most important feature of the flare is found to be the airplane's deceleration in the flare. Various effects on this are correlated in terms of the average flare load factor. Piloting technique is extensively discussed. Design criteria are presented.

A System for the Measurement of the Subjective Visual Vertical using a Virtual Reality Device.

PubMed

Negrillo-Cárdenas, José; Rueda-Ruiz, Antonio J; Ogayar-Anguita, Carlos J; Lomas-Vega, Rafael; Segura-Sánchez, Rafael J

2018-05-31

The Subjective Visual Vertical (SVV) is a common test for evaluating the perception of verticality. Altered verticality has been connected with disorders in the otolithic, visual or proprioceptive systems, caused by stroke, Parkinson's disease or multiple sclerosis, among others. Currently, this test is carried out using a variety of specific, mostly homemade apparatuses that include moving planes, buckets, hemispheric domes or a line projected in a screen. Our aim is to develop a flexible, inexpensive, user-friendly and easily extensible system based on virtual reality for the measurement of the SVV and several related visual diagnostic tests, and validate it through an experimental evaluation. Two different hardware configurations were tested with 50 healthy volunteers in a controlled environment; 28 of them were males and 22 females, with ages ranging from 18 to 49 years, being 23 the average age. The Intraclass Correlation Coefficient (ICC) was computed in each device. In addition, a usability survey was conducted. ICC = 0.85 in the first configuration (CI = 0.75-0.92), ICC = 0.76 in the second configuration (CI = 0.61-0.87), both with 95% of confidence, which means a substantial reliability. Moreover, 92.2% of subjects rated the usability of the system as "very good". Our evaluation showed that the proposed system is suitable for the measurement of SVV in healthy subjects. The next step is to perform a more elaborated experimentation on patients and compare the results with the measurements obtained from traditional methods.

[Electronic spectra of triphenodioxazines dyes by modified PPP-MO method].

PubMed

Wang, Xue-jie

2002-02-01

The triphenodioxazines dyes have good colour and luster, excellent colour fastness to light, and strong painted. They are used as the dyes and pigment extensively, and also be used as the photoelectronic transformation, laser dyes and far-infrared anti-radiation material. The colour and constitution of triphenodioxazines dyes were evaluated by means of the modified PPP-SCF-MO method with variable R, beta approximation. The calculated wavelengths of maximum absorption are in good agreement with experimental results. It was found that there exists a good correlated relationship between the wavenumber of fluorescence maximum nu fl and the calculated fluorescence emission energy delta Efl, as nu fl = 11.6837 delta Efl + 3.3485(k.cm-1), r = 0.9547. The relationship between structure of molecular and properties of electronic spectra has been discussed.

Shear thinning of the Lennard-Jones fluid by molecular dynamics

NASA Astrophysics Data System (ADS)

Heyes, David M.

1985-11-01

Extensive Molecular Dynamics, MD, calculations of the Lennard-Jones, LJ, rheological equation of state have been made. Non-equilibrium MD permits evaluation of shear thinning of the dense LJ liquid which adheres in behaviour quite closely with that of more complex “real molecules”. However, quantitative correspondence with simple analytic formulae for non-Newtonian behaviour used in the treatment of experimental data is hindered by poor prediction of certain key parameters. For example, at low shear rates, the equilibrium Newtonian viscosity and, at high shear rates, a limiting shear stress are often required. Both are difficult to obtain by simulation in the portion of the LJ phase diagram which exhibits significant shear thinning and using present techniques. Suggestions for improving the Eyring model for shear thinning are made.

Human guinea pigs and the ethics of experimentation: the BMJ's correspondent at the Nuremberg medical trial.

PubMed Central

Weindling, P.

1996-01-01

Though the Nuremberg medical trial was a United States military tribunal, British forensic pathologists supplied extensive evidence for the trial. The BMJ had a correspondent at the trial, and he endorsed a utilitarian legitimation of clinical experiments, justifying the medical research carried out under Nazism as of long term scientific benefit despite the human costs. The British supported an international medical commission to evaluate the ethics and scientific quality of German research. Medical opinions differed over whether German medical atrocities should be given publicity or treated in confidence. The BMJ's correspondent warned against medical researchers being taken over by a totalitarian state, and these arguments were used to oppose the NHS and any state control over medical research. Images Fig 1 PMID:8973237

Air-Coupled Ultrasonic Measurements in Composites

NASA Astrophysics Data System (ADS)

Kommareddy, V.; Peters, J. J.; Dayal, V.; Hsu, D. K.

2004-02-01

Air-coupled ultrasound is a non-contact technique and has clear advantages over water-coupled testing. Research of air-coupled ultrasonics, especially using capacitance and micromachined transducers, has been extensively reported in the literature. This paper reports our experience of applying piezoceramic air-coupled transducers for nondestructive evaluation of composites. The beam profiles of air-coupled piezoceramic transducers, with and without apodization, were mapped out. The transmission of air-coupled ultrasonic energy through composite plates of different thickness was measured experimentally; model calculation of the transmission coefficient, taking into account the frequency bandwidth of the transducer, agreed with the measurement results. The occurrence of diffraction phenomenon ("Poisson bright spot") while imaging flaws in composite laminates was investigated. The resolution of scanned images obtained with air-coupled transducers was investigated for different frequency, focusing, and apodization conditions.

A Benders based rolling horizon algorithm for a dynamic facility location problem

DOE PAGES

Marufuzzaman,, Mohammad; Gedik, Ridvan; Roni, Mohammad S.

2016-06-28

This study presents a well-known capacitated dynamic facility location problem (DFLP) that satisfies the customer demand at a minimum cost by determining the time period for opening, closing, or retaining an existing facility in a given location. To solve this challenging NP-hard problem, this paper develops a unique hybrid solution algorithm that combines a rolling horizon algorithm with an accelerated Benders decomposition algorithm. Extensive computational experiments are performed on benchmark test instances to evaluate the hybrid algorithm’s efficiency and robustness in solving the DFLP problem. Computational results indicate that the hybrid Benders based rolling horizon algorithm consistently offers high qualitymore » feasible solutions in a much shorter computational time period than the standalone rolling horizon and accelerated Benders decomposition algorithms in the experimental range.« less

Evaluation of 1.5-T Cell Flash Memory Total Ionizing Dose Response

NASA Astrophysics Data System (ADS)

Clark, Lawrence T.; Holbert, Keith E.; Adams, James W.; Navale, Harshad; Anderson, Blake C.

2015-12-01

Flash memory is an essential part of systems used in harsh environments, experienced by both terrestrial and aerospace TID applications. This paper presents studies of COTS flash memory TID hardness. While there is substantial literature on flash memory TID response, this work focuses for the first time on 1.5 transistor per cell flash memory. The experimental results show hardness varying from about 100 krad(Si) to over 250 krad(Si) depending on the usage model. We explore the circuit and device aspects of the results, based on the extensive reliability literature for this flash memory type. Failure modes indicate both device damage and circuit marginalities. Sector erase failure limits, but read only operation allows TID exceeding 200 krad(Si). The failures are analyzed by type.

Nanomedical innovation: the SEON-concept for an improved cancer therapy with magnetic nanoparticles.

PubMed

Lyer, Stefan; Tietze, Rainer; Unterweger, Harald; Zaloga, Jan; Singh, Raminder; Matuszak, Jasmin; Poettler, Marina; Friedrich, Ralf P; Duerr, Stephan; Cicha, Iwona; Janko, Christina; Alexiou, Christoph

2015-01-01

Nanomedicine offers tremendous opportunities for the development of novel therapeutic and diagnostic tools. During the last decades, extensive knowledge was gained about stabilizing and the coating of nanoparticles, their functionalization for drug binding and drug release and possible strategies for therapies and diagnostics of different diseases. Most recently, more and more emphasis has been placed on nanotoxicology and nanosafety aspects. The section of experimental oncology and nanomedicine developed a concept for translating this knowledge into clinical application of magnetic drug targeting for the treatment of cancer and other diseases using superparamagnetic iron oxide nanoparticles. This approach includes reproducible synthesis, detailed characterization, nanotoxicological testing, evaluation in ex vivo models, preclinical animal studies and production of superparamagnetic iron oxide nanoparticles according to good manufacturing practice regulations.

Friendly protection of houses by affordable isolation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazzolani, Federico M.; Mandara, Alberto; Froncillo, Salvatore

2008-07-08

The paper deals with a case of seismic isolation carried out in Campania (Italy), referring to the construction of a house building. The concerned case is a three-storey reinforced concrete frame building, in which the isolation system has been applied between the basement top and the first floor deck. The paper reports the main steps of this work, starting from the design, carried out according to the latest Italian seismic code, going throughout the construction stage, up to the extensive on-site testing program performed to evaluate the dynamic response of the building. Relevant technological solutions are illustrated and discussed. Bothmore » theoretical calculation and experimental measurements demonstrate the effectiveness of the solution adopted, not only from the technical point of view, but also in an economic perspective.« less

Experimental demonstration of software defined data center optical networks with Tbps end-to-end tunability

NASA Astrophysics Data System (ADS)

Zhao, Yongli; Zhang, Jie; Ji, Yuefeng; Li, Hui; Wang, Huitao; Ge, Chao

2015-10-01

The end-to-end tunability is important to provision elastic channel for the burst traffic of data center optical networks. Then, how to complete the end-to-end tunability based on elastic optical networks? Software defined networking (SDN) based end-to-end tunability solution is proposed for software defined data center optical networks, and the protocol extension and implementation procedure are designed accordingly. For the first time, the flexible grid all optical networks with Tbps end-to-end tunable transport and switch system have been online demonstrated for data center interconnection, which are controlled by OpenDayLight (ODL) based controller. The performance of the end-to-end tunable transport and switch system has been evaluated with wavelength number tuning, bit rate tuning, and transmit power tuning procedure.

Assessing Aircraft Susceptibility to Nonlinear Aircraft-Pilot Coupling/Pilot-Induced Oscillations

NASA Technical Reports Server (NTRS)

Hess, R.A.; Stout, P. W.

1997-01-01

A unified approach for assessing aircraft susceptibility to aircraft-pilot coupling (or pilot-induced oscillations) which was previously reported in the literature and applied to linear systems is extended to nonlinear systems, with emphasis upon vehicles with actuator rate saturation. The linear methodology provided a tool for predicting: (1) handling qualities levels, (2) pilot-induced oscillation rating levels and (3) a frequency range in which pilot-induced oscillations are likely to occur. The extension to nonlinear systems provides a methodology for predicting the latter two quantities. Eight examples are presented to illustrate the use of the technique. The dearth of experimental flight-test data involving systematic variation and assessment of the effects of actuator rate limits presently prevents a more thorough evaluation of the methodology.

Assessment of the neutron dose field around a biomedical cyclotron: FLUKA simulation and experimental measurements.

PubMed

Infantino, Angelo; Cicoria, Gianfranco; Lucconi, Giulia; Pancaldi, Davide; Vichi, Sara; Zagni, Federico; Mostacci, Domiziano; Marengo, Mario

2016-12-01

In the planning of a new cyclotron facility, an accurate knowledge of the radiation field around the accelerator is fundamental for the design of shielding, the protection of workers, the general public and the environment. Monte Carlo simulations can be very useful in this process, and their use is constantly increasing. However, few data have been published so far as regards the proper validation of Monte Carlo simulation against experimental measurements, particularly in the energy range of biomedical cyclotrons. In this work a detailed model of an existing installation of a GE PETtrace 16.5MeV cyclotron was developed using FLUKA. An extensive measurement campaign of the neutron ambient dose equivalent H ∗ (10) in marked positions around the cyclotron was conducted using a neutron rem-counter probe and CR39 neutron detectors. Data from a previous measurement campaign performed by our group using TLDs were also re-evaluated. The FLUKA model was then validated by comparing the results of high-statistics simulations with experimental data. In 10 out of 12 measurement locations, FLUKA simulations were in agreement within uncertainties with all the three different sets of experimental data; in the remaining 2 positions, the agreement was with 2/3 of the measurements. Our work allows to quantitatively validate our FLUKA simulation setup and confirms that Monte Carlo technique can produce accurate results in the energy range of biomedical cyclotrons. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Assessing the accuracy of subject-specific, muscle-model parameters determined by optimizing to match isometric strength.

PubMed

DeSmitt, Holly J; Domire, Zachary J

2016-12-01

Biomechanical models are sensitive to the choice of model parameters. Therefore, determination of accurate subject specific model parameters is important. One approach to generate these parameters is to optimize the values such that the model output will match experimentally measured strength curves. This approach is attractive as it is inexpensive and should provide an excellent match to experimentally measured strength. However, given the problem of muscle redundancy, it is not clear that this approach generates accurate individual muscle forces. The purpose of this investigation is to evaluate this approach using simulated data to enable a direct comparison. It is hypothesized that the optimization approach will be able to recreate accurate muscle model parameters when information from measurable parameters is given. A model of isometric knee extension was developed to simulate a strength curve across a range of knee angles. In order to realistically recreate experimentally measured strength, random noise was added to the modeled strength. Parameters were solved for using a genetic search algorithm. When noise was added to the measurements the strength curve was reasonably recreated. However, the individual muscle model parameters and force curves were far less accurate. Based upon this examination, it is clear that very different sets of model parameters can recreate similar strength curves. Therefore, experimental variation in strength measurements has a significant influence on the results. Given the difficulty in accurately recreating individual muscle parameters, it may be more appropriate to perform simulations with lumped actuators representing similar muscles.

The heavy top quark and supersymmetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hall, L.J.

1997-01-01

Three aspects of supersymmetric theories are discussed: electroweak symmetry breaking, the issues of flavor, and gauge unification. The heavy top quark plays an important, sometimes dominant, role in each case. Additional symmetries lead to extensions of the Standard Model which can provide an understanding for many of the outstanding problems of particle physics. A broken supersymmetric extension of spacetime allows electroweak symmetry breaking to follow from the dynamics of the heavy top quark; an extension of isospin provides a constrained framework for understanding the pattern of quark and lepton masses; and a grand unified extension of the Standard Model gaugemore » group provides an elegant understanding of the gauge quantum numbers of the components of a generation. Experimental signatures for each of these additional symmetries are discussed.« less

Exploring bacterial infections: theoretical and experimental studies of the bacterial population dynamics and antibiotic treatment

NASA Astrophysics Data System (ADS)

Shao, Xinxian

Bacterial infections are very common in human society. Thus extensive research has been conducted to reveal the molecular mechanisms of the pathogenesis and to evaluate the antibiotics' efficacy against bacteria. Little is known, however, about the population dynamics of bacterial populations and their interactions with the host's immune system. In this dissertation, a stochatic model is developed featuring stochastic phenotypic switching of bacterial individuals to explain the single-variant bottleneck discovered in multi strain bacterial infections. I explored early events in a bacterial infection establishment using classical experiments of Moxon and Murphy on neonatal rats. I showed that the minimal model and its simple variants do not work. I proposed modifications to the model that could explain the data quantitatively. The bacterial infections are also commonly established in physical structures, as biofilms or 3-d colonies. In contrast, most research on antibiotic treatment of bacterial infections has been conducted in well-mixed liquid cultures. I explored the efficacy of antibiotics to treat such bacterial colonies, a broadly applicable method is designed and evaluated where discrete bacterial colonies on 2-d surfaces were exposed to antibiotics. I discuss possible explanations and hypotheses for the experimental results. To verify these hypotheses, we investigated the dynamics of bacterial population as 3-d colonies. We showed that a minimal mathematical model of bacterial colony growth in 3-d was able to account for the experimentally observed presence of a diffusion-limited regime. The model further revealed highly loose packing of the cells in 3-d colonies and smaller cell sizes in colonies than plancktonic cells in corresponding liquid culture. Further experimental tests of the model predictions have revealed that the ratio of the cell size in liquid culture to that in colony cultures was consistent with the model prediction, that the dead cells emerged randomly in a colony, and that the cells packed heterogeneously in the outer part of a colony, possibly explaining the loose packing.

Critical evaluation of measured rotational-vibrational transitions of four sulphur isotopologues of S16O2

NASA Astrophysics Data System (ADS)

Tóbiás, Roland; Furtenbacher, Tibor; Császár, Attila G.; Naumenko, Olga V.; Tennyson, Jonathan; Flaud, Jean-Marie; Kumar, Praveen; Poirier, Bill

2018-03-01

A critical evaluation and validation of the complete set of previously published experimental rotational-vibrational line positions is reported for the four stable sulphur isotopologues of the semirigid SO2 molecule - i.e., 32S16O2, 33S16O2, 34S16O2, and 36S16O2. The experimentally measured, assigned, and labeled transitions are collated from 43 sources. The 32S16O2, 33S16O2, 34S16O2, and 36S16O2 datasets contain 40,269, 15,628, 31,080, and 31 lines, respectively. Of the datasets collated, only the extremely limited 36S16O2 dataset is not subjected to a detailed analysis. As part of a detailed analysis of the experimental spectroscopic networks corresponding to the ground electronic states of the 32S16O2, 33S16O2, and 34S16O2 isotopologues, the MARVEL (Measured Active Rotational-Vibrational Energy Levels) procedure is used to determine the rovibrational energy levels. The rovibrational levels and their vibrational parent and asymmetric-top quantum numbers are compared to ones obtained from accurate variational nuclear-motion computations as well as to results of carefully designed effective Hamiltonian models. The rovibrational energy levels of the three isotopologues having the same labels are also compared against each other to ensure self-consistency. This careful, multifaceted analysis gives rise to 15,130, 5852, and 10,893 validated rovibrational energy levels, with a typical accuracy of a few 0.0001 cm-1 , for 32S16O2, 33S16O2, and 34S16O2, respectively. The extensive list of validated experimental lines and empirical (MARVEL) energy levels of the S16O2 isotopologues studied are deposited in the Supplementary Material of this article, as well as in the distributed information system ReSpecTh (http://respecth.hu).

Mechanical behavior, damage tolerance and durability of fiber metal laminates for aircraft structures

NASA Astrophysics Data System (ADS)

Wu, Guocai

This study systematically explores the mechanical behavior, damage tolerance and durability of fiber metal laminates, a promising candidate materials system for next generation aerospace structures. The experimental results indicated that GLARE laminates exhibited a bilinear deformation behavior under static in-plane loading. Both an analytical constitutive model based on a modified classical lamination theory which incorporates the elasto-plastic behavior of aluminum alloy and a numerical simulation based on finite element modeling are used to predict the nonlinear stress-strain response and deformation behavior of GLARE laminates. The blunt notched strength of GLARE laminates increased with decreasing specimen width and decreasing hole diameter. The notched strength of GLARE laminates was evaluated based on a modified point stress criterion. A computer simulation based on finite element method was performed to study stress concentration and distribution around the notch and verify the analytical and experimental results of notched strength. Good agreement is obtained between the model predictions and experimental results. Experimental results also indicate that GLARE laminates exhibited superior impact properties to those of monolithic 2024-T3 aluminum alloy at low velocity impact loading. The GLARE 5-2/1 laminate with 0°/90°/90°/0° fiber configuration exhibits a better impact resistance than the GLARE 4-3/2 laminate with 0°/90°/0° fiber orientation. The characteristic impact energies, the damage area, and the permanent deflection of laminates are used to evaluate the impact damage resistance. The post-impact residual tensile strength under various damage states ranging from the plastic dent, barely visible impact damage (BVID), clearly visible impact damage (CVID) up to the complete perforation was also measured and compared. The post-impact fatigue behavior under various stress levels and impact damage states was extensively explored. The damage initiation and progression, failure modes and crack propagation under different loading conditions were investigated and identified with microscopy, SEM, X-ray radiography, and by chemically removing outer aluminum layers.

Theoretical prediction of pullout strengths for dental and orthopaedic screws with conical profile and buttress threads.

PubMed

Shih, Kao-Shang; Hou, Sheng-Mou; Lin, Shang-Chih

2017-12-01

The pullout strength of a screw is an indicator of how secure bone fragments are being held in place. Such bone-purchasing ability is sensitive to bone quality, thread design, and the pilot hole, and is often evaluated by experimental and numerical methods. Historically, there are some mathematical formulae to simulate the screw withdrawal from the synthetic bone. There are great variations in screw specifications. However, extensive investigation of the correlation between experimental and analytical results has not been reported in literature. Referring to the literature formulae, this study aims to evaluate the differences in the calculated pullout strengths. The pullout tests of the surgical screws are measured and the sawbone is used as the testing block. The absolute errors and correlation coefficients of the experimental and analytical results are calculated as the comparison baselines of the formulae. The absolute error of the dental, traumatic, and spinal groups are 21.7%, 95.5%, and 37.0%, respectively. For the screws with a conical profile and/or tiny threads, the calculated and measured results are not well correlated. The formulae are not accurate indicators of the pullout strengths of the screws where the design parameters are slightly varied. However, the experimental and numerical results are highly correlated for the cylindrical screws. The pullout strength of a conical screw is higher than that of its counterpart, but all formulae consistently predict the opposite results. In general, the bony purchase of the buttress threads is securer than that of the symmetric thread. An absolute error of up to 51.4% indicates the theoretical results cannot predict the actual value of the pullout strength. Only thread diameter, pitch, and depth are considered in the investigated formulae. The thread profile and shape should be formulated to modify the slippage mechanism at the bone-screw interfaces and simulate the strength change in the squeezed bones, especially for the conical screw. Copyright © 2017. Published by Elsevier B.V.

Effect of facet joint injection versus systemic steroids in low back pain: a randomized controlled trial.

PubMed

Ribeiro, Luiza Helena; Furtado, Rita Nely Vilar; Konai, Monique Sayuri; Andreo, Ana Beatriz; Rosenfeld, Andre; Natour, Jamil

2013-11-01

Randomized clinical trial. To compare the effectiveness of facet joint injection versus systemic steroid in patients with a diagnosis of facet joint syndrome. The term facet joint syndrome has been used to define back pain originating from the facet joints. Treatment is mainly conservative, although interventions, including intra-articular injections and medial branch nerve blocks are used to manage facet-mediated pain. Several studies have evaluated the effectiveness of these interventions. Results of facet joint injection, however, are conflicting. Sixty subjects with a diagnosis of facet joint syndrome were enrolled in the study. They were randomized into experimental and control groups. The experimental group was administered with intra-articular injection of 6 lumbar facet joints with triamcinolone hexacetonide; the control group was administered with triamcinolone acetonide intramuscular injection of 6 lumbar paravertebral points. Visits were taken at baseline and at 1, 4, 12, and 24 weeks after interventions. Outcome measures were used: pain visual analogue scale, pain visual analogue scale during extension of the spine, Likert scale, improvement percentage scale, Roland-Morris, 36-Item Short Form Health Survey, and accountability of medications taken.Homogeneity was tested using the Student t, Pearson χ, and Mann-Whitney tests. Analysis of variance was used to analyze differences in the groups over time and the Student t test to analyze differences between groups at each time evaluation. The groups were similar at baseline. Comparisons between the groups showed, in analysis of variance analysis, an improvement in the experimental group regarding diclofenac intake and quality of life, in the "role physical" profile, assessed by 36-Item Short Form Health Survey.In the analysis at each time point, an improvement in the experimental group was also found in the Roland-Morris questionnaire, in the improvement percentage scale and in the response to treatment, assessed by the Likert scale. Both treatments were effective, with a slight superiority of the intra-articular injection of steroids over intramuscular injection.

Beneficial effect of Mentha suaveolens essential oil in the treatment of vaginal candidiasis assessed by real-time monitoring of infection

PubMed Central

2011-01-01

Background Vaginal candidiasis is a frequent and common distressing disease affecting up to 75% of the women of fertile age; most of these women have recurrent episodes. Essential oils from aromatic plants have been shown to have antimicrobial and antifungal activities. This study was aimed at assessing the anti-fungal activity of essential oil from Mentha suaveolens (EOMS) in an experimental infection of vaginal candidiasis. Methods The in vitro and in vivo activity of EOMS was assessed. The in vitro activity was evaluated under standard CLSI methods, and the in vivo analysis was carried out by exploiting a novel, non-invasive model of vaginal candidiasis in mice based on an in vivo imaging technique. Differences between essential oil treated and saline treated mice were evaluated by the non-parametric Mann-Whitney U-test. Viable count data from a time kill assay and yeast and hyphae survival test were compared using the Student's t-test (two-tailed). Results Our main findings were: i) EOMS shows potent candidastatic and candidacidal activity in an in vitro experimental system; ii) EOMS gives a degree of protection against vaginal candidiasis in an in vivo experimental system. Conclusions This study shows for the first time that the essential oil of a Moroccan plant Mentha suaveolens is candidastatic and candidacidal in vitro, and has a degree of anticandidal activity in a model of vaginal infection, as demonstrated in an in vivo monitoring imaging system. We conclude that our findings lay the ground for further, more extensive investigations to identify the active EOMS component(s), promising in the therapeutically problematic setting of chronic vaginal candidiasis in humans. PMID:21356078

Experimental investigation of basic oxygen furnace slag used as aggregate in asphalt mixture.

PubMed

Xue, Yongjie; Wu, Shaopeng; Hou, Haobo; Zha, Jin

2006-11-16

Chinese researchers have commenced a great deal of researches on the development of application fields of basic oxygen steel making furnace slag (BOF slag) for many years. Lots of new applications and properties have been found, but few of them in asphalt mixture of road construction engineering. This paper discussed the feasibility of BOF steel slag used as aggregate in asphalt pavement by two points of view including BOF steel slag's physical and micro-properties as well as steel slag asphalt materials and pavement performances. For the former part, this paper mainly concerned the mechanochemistry and physical changes of the steel slag and studied it by performing XRD, SEM, TG and mercury porosimeter analysis and testing method. In the second part, this paper intended to use BOF steel slag as raw material, and design steel slag SMA mixture. By using traditional rutting test, soak wheel track and modified Lottman test, the high temperature stability and water resistance ability were tested. Single axes compression test and indirect tensile test were performed to evaluate the low temperature crack resistance performance and fatigue characteristic. Simultaneously, by observing steel slag SMA pavement which was paved successfully. A follow-up study to evaluate the performance of the experimental pavement confirmed that the experimental pavement was comparable with conventional asphalt pavement, even superior to the later in some aspects. All of above test results and analysis had only one main purpose that this paper validated the opinion that using BOF slag in asphalt concrete is feasible. So this paper suggested that treated and tested steel slag should be used in a more extensive range, especially in asphalt mixture paving projects in such an abundant steel slag resource region.

Effects of fin clipping on survival and position-holding behavior of brown darters, Etheostoma edwini

USGS Publications Warehouse

Champagne, C.E.; Austin, J.D.; Jelks, H.L.; Jordan, F.

2008-01-01

Advent of the polymerase chain reaction (PCR) has allowed conservation biologists to use small portions of tissue to obtain genetic material for population genetic and taxonomic study. Fin clips are used extensively in large-sized fishes, but it is unclear how clipping enough fin tissue for genetic analysis will affect survival of smaller fishes such as minnows and darters, which are among the most threatened organisms in North America. We tested for effects of fin clipping on survival and swimming performance of non-threatened Brown Darters (Etheostoma edwini) in order to justify similar tissue collection in co-occurring endangered Okaloosa Darters (E. okaloosae). We collected 48 E. edwini from a small stream in northwest Florida, transported them to the laboratory, and randomly assigned them to one of three experimental groups: control, entire right pectoral fin removed, or rear half of caudal fin removed. Successful amplification of DNA indicated that our fin clips were large enough for genetic analysis using PCR. No mortality occurred during a two-month observation period. Fin regeneration was almost complete and we could not visually distinguish clipped fins from control fins after two months. We then randomly assigned fish into the same three experimental groups, clipped fins, and evaluated their ability to hold position at 20 cm/sec in an experimental flow chamber. Neither fish size nor treatment type affected position-holding behavior. Fin clipping does not adversely affect survival and swimming performance of E. edwini maintained in the laboratory. Additional research on the effects of fin clipping on small-sized fishes should be conducted in the field to evaluate survival under natural conditions. ?? 2008 by the American Society of Ichthyologists and Herpetologists.

Formulation and experimental evaluation of closed-form control laws for the rapid maneuvering of reactor neutronic power

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernard, J.A.

1989-09-01

This report describes both the theoretical development and the experimental evaluation of a novel, robust methodology for the time-optimal adjustment of a reactor's neutronic power under conditions of closed-loop digital control. Central to the approach are the MIT-SNL Period-Generated Minimum Time Control Laws' which determine the rate at which reactivity should be changed in order to cause a reactor's neutronic power to conform to a specified trajectory. Using these laws, reactor power can be safely raised by five to seven orders of magnitude in a few seconds. The MIT-SNL laws were developed to facilitate rapid increases of neutronic power onmore » spacecraft reactors operating in an SDI environment. However, these laws are generic and have other applications including the rapid recovery of research and test reactors subsequent to an unanticipated shutdown, power increases following the achievement of criticality on commercial reactors, power adjustments on commercial reactors so as to minimize thermal stress, and automated startups. The work reported here was performed by the Massachusetts Institute of Technology under contract to the Sandia National Laboratories. Support was also provided by the US Department of Energy's Division of University and Industry Programs. The work described in this report is significant in that a novel solution to the problem of time-optimal control of neutronic power was identified, in that a rigorous description of a reactor's dynamics was derived in that the rate of change of reactivity was recognized as the proper control signal, and in that extensive experimental trials were conducted of these newly developed concepts on actual nuclear reactors. 43 refs., 118 figs., 11 tabs.« less

A novel experimental design method to optimize hydrophilic matrix formulations with drug release profiles and mechanical properties.

PubMed

Choi, Du Hyung; Lim, Jun Yeul; Shin, Sangmun; Choi, Won Jun; Jeong, Seong Hoon; Lee, Sangkil

2014-10-01

To investigate the effects of hydrophilic polymers on the matrix system, an experimental design method was developed to integrate response surface methodology and the time series modeling. Moreover, the relationships among polymers on the matrix system were studied with the evaluation of physical properties including water uptake, mass loss, diffusion, and gelling index. A mixture simplex lattice design was proposed while considering eight input control factors: Polyethylene glycol 6000 (x1 ), polyethylene oxide (PEO) N-10 (x2 ), PEO 301 (x3 ), PEO coagulant (x4 ), PEO 303 (x5 ), hydroxypropyl methylcellulose (HPMC) 100SR (x6 ), HPMC 4000SR (x7 ), and HPMC 10(5) SR (x8 ). With the modeling, optimal formulations were obtained depending on the four types of targets. The optimal formulations showed the four significant factors (x1 , x2 , x3 , and x8 ) and other four input factors (x4 , x5 , x6 , and x7 ) were not significant based on drug release profiles. Moreover, the optimization results were analyzed with estimated values, targets values, absolute biases, and relative biases based on observed times for the drug release rates with four different targets. The result showed that optimal solutions and target values had consistent patterns with small biases. On the basis of the physical properties of the optimal solutions, the type and ratio of the hydrophilic polymer and the relationships between polymers significantly influenced the physical properties of the system and drug release. This experimental design method is very useful in formulating a matrix system with optimal drug release. Moreover, it can distinctly confirm the relationships between excipients and the effects on the system with extensive and intensive evaluations. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.

Experimental approach to domino-style basement fault systems with evaporites during extension and subsequent inversion

NASA Astrophysics Data System (ADS)

Ferrer, Oriol; McClay, Ken

2017-04-01

Salt is mechanically weaker than other sedimentary rocks in rift basins. During extension it commonly acts as a strain localizer, decoupling supra- and sub-salt deformation. In this scenario the movement of the subsalt faults combined with the salt migration commonly constraint the development of syncline basins. The shape of these synclines is basically controlled by the thickness and strength of the overlying salt section, as well as by the shapes of the extensional faults, and the magnitudes and slip rates along the faults. The inherited extensional structure, and particularly the continuity of the salt section, plays a key role if the rift basin is subsequently inverted. This research utilizes scaled physical models to analyse the interplay between subsalt structures and suprasalt units during both extension and inversion in domino-style basement fault systems. The experimental program includes twelve analogue models to analyze how the thickness and stratigraphy of the salt unit as well as the thickness of the pre-extensional cover constraint the structural style during extension and subsequent inversion. Different models with the same setup have been used to examine the kinematic evolution. Model kinematics was documented and analyzed combining high-resolution photographs and sub-millimeter resolution scanners. The vertical sections carried out at the end of the experiments have been used to characterize the variations of the structures along strike using new methodologies (3D voxel models in image processing software and 3D seismic). The experimental results show that after extension, rift systems with salt affected by domino-style basement faults don't show the classical growth stratal wedges. In this case synclinal basins develop above the salt on the hangingwall of the basement faults. The evolution of supra- and subsalt deformation is initially decoupled by the salt layer. Salt migrates from the main depocenters towards the edges of the basin constraining the sinking of this basin. As extension progressed, salt was locally depleted above the basement faults. From this point the structural style changed dramatically evolving to a coupled deformation. Welding produces a variation in the position of the basin depocenter that jumps towards a new formed antithetic fault above the depleted area. During inversion this basins were progressively folded and uplifted. Shortcuts formed on subsalt fault whereas the salt section acts as a contractional detachment transferring part of the deformation out of the basin. Changes in thickness of the salt section during the inversion produced primary welds and these permitted the sub-polymer deformation to propagate upwards into the supra-salt layers. These experimental results are compared with seismic examples from different areas of the Southern North Sea.

Evaluation of On-Farm Food Safety Programming in Pennsylvania: Implications for Extension

ERIC Educational Resources Information Center

Nayak, Roshan; Tobin, Daniel; Thomson, Joan; Radhakrishna, Rama; LaBorde, Luke

2015-01-01

Penn State Extension conducted on-farm food safety workshops statewide to train fruit and vegetable growers on Good Agricultural Practices (GAPs). These workshops were evaluated using pre- and post-tests to assess the impact of the training on participating growers. Results indicate overall increases in produce growers' knowledge, attitudes,…

76 FR 24060 - Proposed Extension of Existing Information Collection; Testing, Evaluation, and Approval of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-29

... Extension of Existing Information Collection; Testing, Evaluation, and Approval of Mining Products AGENCY... Reduction Act of 1995 [44 U.S.C. 3506(c)(2)(A)]. This program helps to ensure that requested data can be..., testing, approval and certification, and quality control of mining equipment and components, materials...

Evaluating a New and Aspiring County Extension Director Leadership Education Program: Determining Outcomes and Needed Improvements

ERIC Educational Resources Information Center

Jayaratne, K. S. U.; Owen, Mitchel; Jones, David

2010-01-01

This leadership education evaluation study explored the leadership development outcomes of potential county extension directors and the ways to improve the program. The leadership education program aimed to improve participants' leadership abilities in understanding self, building relationships and managing resources. The analysis of quantitative…

30 CFR 27.11 - Extension of certification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Extension of certification. 27.11 Section 27.11 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS METHANE-MONITORING SYSTEMS General Provisions § 27.11 Extension of...

30 CFR 27.11 - Extension of certification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Extension of certification. 27.11 Section 27.11 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS METHANE-MONITORING SYSTEMS General Provisions § 27.11 Extension of...

Selected advanced aerodynamics and active controls technology concepts development on a derivative B-747 aircraft

NASA Technical Reports Server (NTRS)

1983-01-01

Analytical design and wind tunnel test evaluations covering the feasibility of applying wing tip extensions, winglets, and active control wing had alleviation to the model B747 are described. Aerodynamic improvement offered by wing tip extension and winglet individually, and the combined aerodynamic and weight improvements when wing load alleviation is combined with the tip extension or the winglet are evaluated. Results are presented in the form of incremental effects on weight mission range, fuel usage, cost, and airline operating economics.

Research on Liquidity Risk Evaluation of Chinese A-Shares Market Based on Extension Theory

NASA Astrophysics Data System (ADS)

Bai-Qing, Sun; Peng-Xiang, Liu; Lin, Zhang; Yan-Ge, Li

This research defines the liquidity risk of stock market in matter-element theory and affair-element theory, establishes the indicator system of the forewarning for liquidity risks,designs the model and the process of early warning using the extension set method, extension dependent function and the comprehensive evaluation model. And the paper studies empirically A-shares market through the data of 1A0001, which prove that the model can better describe liquidity risk of China’s A-share market. At last, it gives the corresponding policy recommendations.

Role of the USDA Forest Service experimental forest: an extension point of view

Treesearch

Eric L. Taylor; C. Darwin Foster; Diomy Zamora

2013-01-01

The expansive network of experimental forests (EF) facilitated by the U.S. Forest Service (Forest Service) encompasses a fairly complete representation of the forest ecotypes in the nation. The network, 101 years old this year (2009), has provided researchers with a wealth of long-term data on silviculture, watershed protection, and restoration. However, our nation’s...

Aircraft interior noise prediction using a structural-acoustic analogy in NASTRAN modal synthesis

NASA Technical Reports Server (NTRS)

Grosveld, Ferdinand W.; Sullivan, Brenda M.; Marulo, Francesco

1988-01-01

The noise induced inside a cylindrical fuselage model by shaker excitation is investigated theoretically and experimentally. The NASTRAN modal-synthesis program is used in the theoretical analysis, and the predictions are compared with experimental measurements in extensive graphs. Good general agreement is obtained, but the need for further refinements to account for acoustic-cavity damping and structural-acoustic interaction is indicated.

Experimental StudyHigh Altitude Forced Convective Cooling of Electromechanical Actuation Systems

DTIC Science & Technology

2016-01-01

experimental validation at altitudes above 16,000 feet, relevant to commercial and military aircraft. The convective heat transfer coefficient at altitudes...and natural occurring phenomena. Figure 1.3 also shows that a typical flight ceiling for commercial and military air breathing aircraft is about...However, they have not been extensively vetted in atmospheric conditions experienced by commercial and tactical military aircraft. 1.3 Purpose

Epilepsy in cerebrovascular diseases: Review of experimental and clinical data with meta-analysis of risk factors.

PubMed

Ferlazzo, Edoardo; Gasparini, Sara; Beghi, Ettore; Sueri, Chiara; Russo, Emilio; Leo, Antonio; Labate, Angelo; Gambardella, Antonio; Belcastro, Vincenzo; Striano, Pasquale; Paciaroni, Maurizio; Pisani, Laura Rosa; Aguglia, Umberto

2016-08-01

Seizures may occur in close temporal association with a stroke or after a variable interval. Moreover, epilepsy is often encountered in patients with leukoaraiosis. Although early post-stroke seizures have been studied extensively, less attention has been paid to post-stroke epilepsy (PSE) and to epilepsy associated with leukoaraiosis (EAL). The aim of this paper is to review data concerning pathophysiology, prognosis, and treatment of PSE and EAL. We performed an extensive literature search to identify experimental and clinical articles on PSE and EAL. We also conducted a systematic review of risk factors for PSE and EAL among eligible studies. PSE is caused by enhanced neuronal excitability within and near the scar. The role played by white matter changes in EAL remains to be elucidated. Meta-analysis showed that cortical involvement (odds ratio [OR] 3.71, 95% confidence interval [CI] 2.34-5.90, p < 0.001), cerebral hemorrhage (OR 2.41, 95% CI 1.57-3.70, p < 0.001), and early seizures (OR 4.43, 95% CI 2.36-8.32, p < 0.001) are associated with an increased risk of PSE. As regards EAL, no prospective, population-based studies evaluated the role of different variables on seizure risk. Studies about the management of PSE are limited. PSE is generally well controlled by drugs. Data about risk factors, prognosis, and treatment of EAL are lacking. Pathophysiology and risk factors are well defined for PSE but need to be elucidated for EAL. Management of PSE and EAL relies on the clinician's judgment and should be tailored on an individual basis. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

Influence of bone marrow on osseointegration in long bones: an experimental study in sheep.

PubMed

Morelli, Fabrizio; Lang, Niklaus P; Bengazi, Franco; Baffone, Davide; Vila Morales, C Dadonim; Botticelli, Daniele

2015-03-01

To evaluate the influence of yellow bone marrow on osseointegration of titanium oral implants using a long bone model. The two tibiae of eight sheep were used as experimental sites. Two osteotomies for implant installation were prepared in each tibia. At the control sites, no further treatments were performed while, at the test sites, bone marrow was removed from the osteotomy site with a curette to an extent that exceeded the implant dimensions. As a result, the apical portion of the implants at the control sites was in contact with bone marrow while, at the test sites, it was in contact with the blood clot. After 2 months, the same procedures were performed in the contralateral side. After another month, the animal was sacrificed. Ground sections were obtained for histological analysis. After 1 month of healing, no differences between test and control sites were found in the apical extension of osseointegration and the percentage of new bone-to-implant contact. However, after 3 months of healing, a higher percentage of new bone-to-implant contact was found at the test compared to the control sites in the marrow compartment. The apical extension of osseointegration, however, was similar to that found at the 1-month healing period both for test and control sites. Osseointegration appeared to be favored by the presence of a blood clot when compared to the presence of yellow fatty bone marrow. Moreover, the contact with cortical bone appeared to be a prerequisite for the osseointegration process in the long bone model. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Experimental and Numerical Studies on Development of Fracture Process Zone (FPZ) in Rocks under Cyclic and Static Loadings

NASA Astrophysics Data System (ADS)

Ghamgosar, M.; Erarslan, N.

2016-03-01

The development of fracture process zones (FPZ) in the Cracked Chevron Notched Brazilian Disc (CCNBD) monsonite and Brisbane tuff specimens was investigated to evaluate the mechanical behaviour of brittle rocks under static and various cyclic loadings. An FPZ is a region that involves different types of damage around the pre-existing and/or stress-induced crack tips in engineering materials. This highly damaged area includes micro- and meso-cracks, which emerge prior to the main fracture growth or extension and ultimately coalescence to macrofractures, leading to the failure. The experiments and numerical simulations were designed for this study to investigate the following features of FPZ in rocks: (1) ligament connections and (2) microcracking and its coalescence in FPZ. A Computed Tomography (CT) scan technique was also used to investigate the FPZ behaviour in selected rock specimens. The CT scan results showed that the fracturing velocity is entirely dependent on the appropriate amount of fracture energy absorbed in rock specimens due to the change of frequency and amplitudes of the dynamic loading. Extended Finite Element Method (XFEM) was used to compute the displacements, tensile stress distribution and plastic energy dissipation around the propagating crack tip in FPZ. One of the most important observations, the shape of FPZ and its extension around the crack tip, was made using numerical and experimental results, which supported the CT scan results. When the static rupture and the cyclic rupture were compared, the main differences are twofold: (1) the number of fragments produced is much greater under cyclic loading than under static loading, and (2) intergranular cracks are formed due to particle breakage under cyclic loading compared with smooth and bright cracks along cleavage planes under static loading.

Application of heat pipe technology in permanent mold casting of nonferrous alloys

NASA Astrophysics Data System (ADS)

Elalem, Kaled

The issue of mold cooling is one, which presents a foundry with a dilemma. On the one hand; the use of air for cooling is safe and practical, however, it is not very effective and high cost. On the other hand, water-cooling can be very effective but it raises serious concerns about safety, especially with a metal such as magnesium. An alternative option that is being developed at McGill University uses heat pipe technology to carry out the cooling. The experimental program consisted of designing a permanent mold to produce AZ91E magnesium alloy and A356 aluminum alloy castings with shrinkage defects. Heat pipes were then used to reduce these defects. The heat pipes used in this work are novel and are patent pending. They are referred to as McGill Heat Pipes. Computer modeling was used extensively in designing the mold and the heat pipes. Final designs for the mold and the heat pipes were chosen based on the modeling results. Laboratory tests of the heat pipe were performed before conducting the actual experimental plan. The laboratory testing results verified the excellent performance of the heat pipes as anticipated by the model. An industrial mold made of H13 tool steel was constructed to cast nonferrous alloys. The heat pipes were installed and initial testing and actual industrial trials were conducted. This is the first time where a McGill heat pipe was used in an industrial permanent mold casting process for nonferrous alloys. The effects of cooling using heat pipes on AZ91E and A356 were evaluated using computer modeling and experimental trials. Microstructural analyses were conducted to measure the secondary dendrite arm spacing, SDAS, and the grain size to evaluate the cooling effects on the castings. The modeling and the experimental results agreed quite well. The metallurgical differences between AZ91E and A356 were investigated using modeling and experimental results. Selected results from modeling, laboratory and industrial trials are presented. The results show a promising future for heat pipe technology in cooling permanent molds for the casting of nonferrous alloys.

Integrated trimodal SSEP experimental setup for visual, auditory and tactile stimulation

NASA Astrophysics Data System (ADS)

Kuś, Rafał; Spustek, Tomasz; Zieleniewska, Magdalena; Duszyk, Anna; Rogowski, Piotr; Suffczyński, Piotr

2017-12-01

Objective. Steady-state evoked potentials (SSEPs), the brain responses to repetitive stimulation, are commonly used in both clinical practice and scientific research. Particular brain mechanisms underlying SSEPs in different modalities (i.e. visual, auditory and tactile) are very complex and still not completely understood. Each response has distinct resonant frequencies and exhibits a particular brain topography. Moreover, the topography can be frequency-dependent, as in case of auditory potentials. However, to study each modality separately and also to investigate multisensory interactions through multimodal experiments, a proper experimental setup appears to be of critical importance. The aim of this study was to design and evaluate a novel SSEP experimental setup providing a repetitive stimulation in three different modalities (visual, tactile and auditory) with a precise control of stimuli parameters. Results from a pilot study with a stimulation in a particular modality and in two modalities simultaneously prove the feasibility of the device to study SSEP phenomenon. Approach. We developed a setup of three separate stimulators that allows for a precise generation of repetitive stimuli. Besides sequential stimulation in a particular modality, parallel stimulation in up to three different modalities can be delivered. Stimulus in each modality is characterized by a stimulation frequency and a waveform (sine or square wave). We also present a novel methodology for the analysis of SSEPs. Main results. Apart from constructing the experimental setup, we conducted a pilot study with both sequential and simultaneous stimulation paradigms. EEG signals recorded during this study were analyzed with advanced methodology based on spatial filtering and adaptive approximation, followed by statistical evaluation. Significance. We developed a novel experimental setup for performing SSEP experiments. In this sense our study continues the ongoing research in this field. On the other hand, the described setup along with the presented methodology is a considerable improvement and an extension of methods constituting the state-of-the-art in the related field. Device flexibility both with developed analysis methodology can lead to further development of diagnostic methods and provide deeper insight into information processing in the human brain.

Experimental results on gamma-ray sources at E sub 0 = 10(13) - 10(14) eV

NASA Technical Reports Server (NTRS)

Morello, C.; Navarra, G.; Periale, L.; Vallania, P.

1985-01-01

The detection of very high energy gamma ray sources has been reported in the last few years by means of extensive air shower observations. The Plateau Rosa array for the registration of the arrival directions of extensive air showers has been operating since 1980 and first results on Cygnus X-3 have been reported. Here, the status of observations of Cygnus X-3 and of the Crab Pulsar are reported.

Performance analysis and experimental study on rainfall water purification with an extensive green roof matrix layer in Shanghai, China.

PubMed

Guo, Jiankang; Zhang, Yanting; Che, Shengquan

2018-02-01

Current research has validated the purification of rainwater by a substrate layer of green roofs to some extent, though the effects of the substrate layer on rainwater purification have not been adequately quantified. The present study set up nine extensive green roof experiment combinations based on the current conditions of precipitation characteristics observed in Shanghai, China. Different rain with pollutants were simulated, and the orthogonal design L9 (33) test was conducted to measure purification performance. The purification influences of the extensive green roof substrate layer were quantitatively analyzed in Shanghai to optimize the thickness, proportion of substrate, and sodium polyacrylate content. The experimental outcomes resulted in ammonium nitrogen (NH 4 + -N), lead (Pb), and zinc (Zn) removal of up to 93.87%, 98.81%, and 94.55% in the artificial rainfall, respectively, and NH 4 + -N, Pb, and Zn event mean concentration (EMC) was depressed to 0.263 mg/L, 0.002 mg/L and 0.018 mg/L, respectively, which were all well below the pollutant concentrations of artificial rainfall. With reference to the rainfall chemical characteristics of Shanghai, a combination of a 200 mm thickness, proportions of 1:1:2 of Loam: Perlite: Cocopeat and 2 g/L sodium polyacrylate content was suggested for the design of an extensive green roof substrate to purify NH 4 + -N, Pb and Zn.

Interdisciplinary Professional Development Needs of Cooperative Extension Field Educators

ERIC Educational Resources Information Center

Sondgerath, Travis

2016-01-01

The study discussed in this article sought to identify cross-program professional development needs of county-based Extension professionals (field educators). The study instrument was completed by 105 county-based Extension professionals. Interdisciplinary topics, such as program evaluation and volunteer management, were identified as subjects of…

Materials Science News | Materials Science | NREL

Science.gov Websites

News Release: NREL Opens Large Database of Inorganic Thin-Film Materials An extensive experimental developing a rechargeable non-aqueous magnesium-metal battery. January 30, 2018 Dave Moore: Taking Roundabout

Evaluation of the Neutron Data Standards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carlson, A. D.; Pronyaev, V. G.; Capote, R.

With the need for improving existing nuclear data evaluations, (e.g., ENDF/B-VIII.0 and JEFF-3.3 releases) the first step was to evaluate the standards for use in such a library. This new standards evaluation made use of improved experimental data and some developments in the methodology of analysis and evaluation. In addition to the work on the traditional standards, this work produced the extension of some energy ranges and includes new reactions that are called reference cross sections. Since the effort extends beyond the traditional standards, it is called the neutron data standards evaluation. This international effort has produced new evaluations ofmore » the following cross section standards: the H(n,n), 6Li(n,t), 10B(n,α), 10B(n,α 1γ), natC(n,n), Au(n,γ), 235U(n,f) and 238U(n,f). Also in the evaluation process the 238U(n,γ) and 239Pu(n,f) cross sections that are not standards were evaluated. Evaluations were also obtained for data that are not traditional standards: the Maxwellian spectrum averaged cross section for the Au(n,γ) cross section at 30 keV; reference cross sections for prompt γ-ray production in fast neutron-induced reactions; reference cross sections for very high energy fission cross sections; the 252Cf spontaneous fission neutron spectrum and the 235U prompt fission neutron spectrum induced by thermal incident neutrons; and the thermal neutron constants. The data and covariance matrices of the uncertainties were obtained directly from the evaluation procedure.« less

Evaluation of the Neutron Data Standards

DOE PAGES

Carlson, A. D.; Pronyaev, V. G.; Capote, R.; ...

2018-02-01

With the need for improving existing nuclear data evaluations, (e.g., ENDF/B-VIII.0 and JEFF-3.3 releases) the first step was to evaluate the standards for use in such a library. This new standards evaluation made use of improved experimental data and some developments in the methodology of analysis and evaluation. In addition to the work on the traditional standards, this work produced the extension of some energy ranges and includes new reactions that are called reference cross sections. Since the effort extends beyond the traditional standards, it is called the neutron data standards evaluation. This international effort has produced new evaluations ofmore » the following cross section standards: the H(n,n), 6Li(n,t), 10B(n,α), 10B(n,α 1γ), natC(n,n), Au(n,γ), 235U(n,f) and 238U(n,f). Also in the evaluation process the 238U(n,γ) and 239Pu(n,f) cross sections that are not standards were evaluated. Evaluations were also obtained for data that are not traditional standards: the Maxwellian spectrum averaged cross section for the Au(n,γ) cross section at 30 keV; reference cross sections for prompt γ-ray production in fast neutron-induced reactions; reference cross sections for very high energy fission cross sections; the 252Cf spontaneous fission neutron spectrum and the 235U prompt fission neutron spectrum induced by thermal incident neutrons; and the thermal neutron constants. The data and covariance matrices of the uncertainties were obtained directly from the evaluation procedure.« less

Evaluation of the Neutron Data Standards

NASA Astrophysics Data System (ADS)

Carlson, A. D.; Pronyaev, V. G.; Capote, R.; Hale, G. M.; Chen, Z.-P.; Duran, I.; Hambsch, F.-J.; Kunieda, S.; Mannhart, W.; Marcinkevicius, B.; Nelson, R. O.; Neudecker, D.; Noguere, G.; Paris, M.; Simakov, S. P.; Schillebeeckx, P.; Smith, D. L.; Tao, X.; Trkov, A.; Wallner, A.; Wang, W.

2018-02-01

With the need for improving existing nuclear data evaluations, (e.g., ENDF/B-VIII.0 and JEFF-3.3 releases) the first step was to evaluate the standards for use in such a library. This new standards evaluation made use of improved experimental data and some developments in the methodology of analysis and evaluation. In addition to the work on the traditional standards, this work produced the extension of some energy ranges and includes new reactions that are called reference cross sections. Since the effort extends beyond the traditional standards, it is called the neutron data standards evaluation. This international effort has produced new evaluations of the following cross section standards: the H(n,n), 6Li(n,t), 10B(n,α), 10B(n,α1 γ), natC(n,n), Au(n,γ), 235U(n,f) and 238U(n,f). Also in the evaluation process the 238U(n,γ) and 239Pu(n,f) cross sections that are not standards were evaluated. Evaluations were also obtained for data that are not traditional standards: the Maxwellian spectrum averaged cross section for the Au(n,γ) cross section at 30 keV; reference cross sections for prompt γ-ray production in fast neutron-induced reactions; reference cross sections for very high energy fission cross sections; the 252Cf spontaneous fission neutron spectrum and the 235U prompt fission neutron spectrum induced by thermal incident neutrons; and the thermal neutron constants. The data and covariance matrices of the uncertainties were obtained directly from the evaluation procedure.

Predicted Turbine Heat Transfer for a Range of Test Conditions

NASA Technical Reports Server (NTRS)

Boyle, R. J.; Lucci, B. L.

1996-01-01

Comparisons are shown between predictions and experimental data for blade and endwall heat transfer. The comparisons of computational domain parisons are given for both vane and rotor geometries over an extensive range of Reynolds and Mach numbers. Comparisons are made with experimental data from a variety of sources. A number of turbulence models are available for predicting blade surface heat transfer, as well as aerodynamic performance. The results of an investigation to determine the turbulence model which gives the best agreement with experimental data over a wide range of test conditions are presented.

Two types of lateral extension in juvenile nasopharyngeal angiofibroma: diagnostic and therapeutic management.

PubMed

Szymańska, Anna; Szymański, Marcin; Czekajska-Chehab, Elżbieta; Szczerbo-Trojanowska, Małgorzata

2015-01-01

Juvenile nasopharyngeal angiofibroma is a benign, locally aggressive nasopharyngeal tumor. Apart from anterior lateral extension to the pterygopalatine fossa, it may spread laterally posterior to the pterygoid process, showing posterior lateral growth pattern, which is less common and more difficult to identify during surgery. We analyzed the routes of lateral spread, modalities useful in its diagnosis, the incidence of lateral extension and its influence on outcomes of surgical treatment. The records of 37 patients with laterally extending JNA treated at our institution between 1987 and 2011 were retrospectively evaluated. Computed tomography was performed in all patients and magnetic resonance imaging in 17 (46 %) patients. CT and MRI were evaluated to determine routes and extension of JNA lateral spread. Anterior lateral extension to the pterygopalatine fossa occurred in 36 (97 %) patients and further to the infratemporal fossa in 20 (54 %) patients. In 16 (43 %) cases posterior lateral spread was observed: posterior to the pterygoid process and/or between its plates. The recurrence rate was 29.7 % (11/37). The majority of residual lesions was located behind the pterygoid process (7/11). Recurrent disease occurred in 3/21 patients with anterior lateral extension, in 7/15 patients with both types of lateral extensions and in 1 patient with posterior lateral extension. JNA posterior lateral extension may spread behind the pterygoid process or between its plates. The recurrence rate in patients with anterior and/or posterior lateral extension is significantly higher than in patients with anterior lateral extension only. Both CT and MRI allow identification of the anterior and posterior lateral extensions.

Evaluation of an Extension-Delivered Resource for Accelerating Progress in Childhood Obesity Prevention: The BEPA-Toolkit

ERIC Educational Resources Information Center

Gunter, Katherine B.; Abi Nader, Patrick; Armington, Amanda; Hicks, John C.; John, Deborah

2017-01-01

The Balanced Energy Physical Activity Toolkit, or the BEPA-Toolkit, supports physical activity (PA) programming via Extension in elementary schools. In a pilot study, we evaluated the effectiveness of the BEPA-Toolkit as used by teachers through Supplemental Nutrition Assistance Program Education partnerships. We surveyed teachers (n = 57)…

A Quantitative Assessment of an Outsourced Agricultural Extension Service in the Umzimkhulu District of KwaZulu-Natal, South Africa

ERIC Educational Resources Information Center

Lyne, Michael C.; Jonas, Nomonde; Ortmann, Gerald F.

2018-01-01

Purpose: This study evaluates the impact of an outsourced extension service delivered by Lima Rural Development Foundation (Lima) in the Umzimkhulu district of South Africa. The evaluation is conducted at both the household and program levels. Design/methodology/approach: Household impacts were estimated using two-stage regression with…

Demonstrating Impact through Replicable Analysis: Implications of an Evaluation of Arkansas's Expanded Food and Nutrition Education Program

ERIC Educational Resources Information Center

Phelps, Josh; Brite-Lane, Allison; Crook, Tina; Hakkak, Reza; Fuller, Serena

2017-01-01

The evaluation described in this article focused on the effectiveness of Arkansas's Extension-based Expanded Food and Nutrition Education Program (EFNEP) but demonstrates an analytic approach that may be useful across Extension programs. We analyzed data from 1,810 Arkansas EFNEP participants' entry and exit Behavior Checklists to assess…

Engagement, Exploration, Explanation, Extension, and Evaluation (5E) Learning Cycle and Conceptual Change Text as Learning Tools

ERIC Educational Resources Information Center

Balci, Sibel; Cakiroglu, Jale; Tekkaya, Ceren

2006-01-01

The purpose of this study is to investigate the effects of the Engagement, Exploration, Explanation, Extension, and Evaluation (5E) learning cycle, conceptual change texts, and traditional instructions on 8th grade students' understanding of photosynthesis and respiration in plants. Students' understanding of photosynthesis and respiration in…

Use of Interactive Electronic Audience Response Tools (Clickers) to Evaluate Knowledge Gained in Extension Programming

ERIC Educational Resources Information Center

Gunn, Patrick; Loy, Dan

2015-01-01

Effectively measuring short-term impact, particularly a change in knowledge resulting from Extension programming, can prove to be challenging. Clicker-based technology, when used properly, is one alternative that may allow educators to better evaluate this aspect of the logic model. While the potential interface between clicker technology and…

Development of polyphenylquinoxaline graphite composites

NASA Technical Reports Server (NTRS)

Hoggatt, J. T.; Hergenrother, P. M.; Shdo, J. G.

1973-01-01

The potential of polyphenylquinoxaline (PPQ)/graphite composites to serve as structural material at 316 C (600 F)has been demonstrated using a block copolymer, BlCo(13), PPQ derivative. Initially, thirteen polyphenylquinoxalines were evaluated. From this work, four candidate polymers were selected for preliminary evaluation as matrices for HMS graphite fiber reinforced composites. The preliminary composite evaluation enabled selection of one of the four polymers for advanced composite preparation and testing. Using an experimentally established cure schedule for each of the four polymers, preliminary laminates of 50% resin volume content, prepared without postcure, were tested for flexure strength and modulus, interlaminar shear strength (short beam), and tensile strength and modulus at ambient temperature. A block copolymer (Bl Co 13) derived from one mole p-bis (phenylglyoxalyl) benzene, one fourth mole 3,3'-diaminobenzidine and three-fourths mole 3,3', 4,4'-tetraminobenzophenone was selected for extensive study. Tensile, flexural, and interlaminar shear values were obtained after aging and testing postcured BlCo(13) laminates at 316 C (600 F). The potential of PPQ/graphite laminates to serve as short term structural materials at temperatures up to 371 C (700 F) was demonstrated through weight loss experiments.

Evaluation of DNA Force Fields in Implicit Solvation

PubMed Central

Gaillard, Thomas; Case, David A.

2011-01-01

DNA structural deformations and dynamics are crucial to its interactions in the cell. Theoretical simulations are essential tools to explore the structure, dynamics, and thermodynamics of biomolecules in a systematic way. Molecular mechanics force fields for DNA have benefited from constant improvements during the last decades. Several studies have evaluated and compared available force fields when the solvent is modeled by explicit molecules. On the other hand, few systematic studies have assessed the quality of duplex DNA models when implicit solvation is employed. The interest of an implicit modeling of the solvent consists in the important gain in the simulation performance and conformational sampling speed. In this study, respective influences of the force field and the implicit solvation model choice on DNA simulation quality are evaluated. To this end, extensive implicit solvent duplex DNA simulations are performed, attempting to reach both conformational and sequence diversity convergence. Structural parameters are extracted from simulations and statistically compared to available experimental and explicit solvation simulation data. Our results quantitatively expose the respective strengths and weaknesses of the different DNA force fields and implicit solvation models studied. This work can lead to the suggestion of improvements to current DNA theoretical models. PMID:22043178

Simulation of gamma-initiated showers

NASA Technical Reports Server (NTRS)

Stamenov, Y.; Vancov, K.; Vodenicharova, T.

1985-01-01

The main average characteristics of muon, electron and hadron components of extensive air showers were calculate using a standard model of nuclear interaction. The obtained results are in good agreement with Tien Shan experimental data.

Experimental assessment of aggregate surfacing materials.

DOT National Transportation Integrated Search

2007-06-30

"An extensive suite of geotechnical laboratory tests were conducted to quantify differences in : engineering properties of three crushed aggregates commonly used on Montana highway projects. The : material types are identified in the Montana Suppleme...

Evaluation of Deep Learning Based Stereo Matching Methods: from Ground to Aerial Images

NASA Astrophysics Data System (ADS)

Liu, J.; Ji, S.; Zhang, C.; Qin, Z.

2018-05-01

Dense stereo matching has been extensively studied in photogrammetry and computer vision. In this paper we evaluate the application of deep learning based stereo methods, which were raised from 2016 and rapidly spread, on aerial stereos other than ground images that are commonly used in computer vision community. Two popular methods are evaluated. One learns matching cost with a convolutional neural network (known as MC-CNN); the other produces a disparity map in an end-to-end manner by utilizing both geometry and context (known as GC-net). First, we evaluate the performance of the deep learning based methods for aerial stereo images by a direct model reuse. The models pre-trained on KITTI 2012, KITTI 2015 and Driving datasets separately, are directly applied to three aerial datasets. We also give the results of direct training on target aerial datasets. Second, the deep learning based methods are compared to the classic stereo matching method, Semi-Global Matching(SGM), and a photogrammetric software, SURE, on the same aerial datasets. Third, transfer learning strategy is introduced to aerial image matching based on the assumption of a few target samples available for model fine tuning. It experimentally proved that the conventional methods and the deep learning based methods performed similarly, and the latter had greater potential to be explored.

Active Aging Promotion: Results from the Vital Aging Program

PubMed Central

Caprara, Mariagiovanna; Molina, María Ángeles; Schettini, Rocío; Santacreu, Marta; Orosa, Teresa; Mendoza-Núñez, Víctor Manuel; Rojas, Macarena; Fernández-Ballesteros, Rocío

2013-01-01

Active aging is one of the terms in the semantic network of aging well, together with others such as successful, productive, competent aging. All allude to the new paradigm in gerontology, whereby aging is considered from a positive perspective. Most authors in the field agree active aging is a multidimensional concept, embracing health, physical and cognitive fitness, positive affect and control, social relationships and engagement. This paper describes Vital Aging, an individual active aging promotion program implemented through three modalities: Life, Multimedia, and e-Learning. The program was developed on the basis of extensive evidence about individual determinants of active aging. The different versions of Vital Aging are described, and four evaluation studies (both formative and summative) are reported. Formative evaluation reflected participants' satisfaction and expected changes; summative evaluations yielded some quite encouraging results using quasi-experimental designs: those who took part in the programs increased their physical exercise, significantly improved their diet, reported better memory, had better emotional balance, and enjoyed more cultural, intellectual, affective, and social activities than they did before the course, thus increasing their social relationships. These results are discussed in the context of the common literature within the field and, also, taking into account the limitations of the evaluations accomplished. PMID:23476644

Short physical performance battery for middle-aged and older adult cardiovascular disease patients: implication for strength tests and lower extremity morphological evaluation.

PubMed

Yasuda, Tomohiro; Fukumura, Kazuya; Nakajima, Toshiaki

2017-04-01

[Purpose] To examine if the SPPB is higher with healthy subjects than outpatients, which was higher than inpatients and if the SPPB can be validated assessment tool for strength tests and lower extremity morphological evaluation in cardiovascular disease patients. [Subjects and Methods] Twenty-four middle aged and older adults with cardiovascular disease were recruited from inpatient and outpatient facilities and assigned to separate experimental groups. Twelve age-matched healthy volunteers were assigned to a control group. SPPB test was used to assess balance and functional motilities. The test outcomes were compared with level of care (inpatient vs. outpatient), physical characteristics, strength and lower extremity morphology. [Results] Total SPPB scores, strength tests (knee extensor muscle strength), and lower extremity morphological evaluation (muscle thickness of anterior and posterior mid-thigh and posterior lower-leg) were greater in healthy subjects and outpatients groups compared with inpatients. To predict total Short Physical Performance Battery scores, the predicted knee extension and anterior mid-thigh muscle thickness were calculated. [Conclusion] The SPPB is an effective tool as the strength tests and lower extremity morphological evaluation for middle-aged and older adult cardiovascular disease patients. Notably, high knee extensor muscle strength and quadriceps femoris muscle thickness are positively associated with high SPPB scores.

LHC benchmark scenarios for the real Higgs singlet extension of the standard model

DOE PAGES

Robens, Tania; Stefaniak, Tim

2016-05-13

Here, we present benchmark scenarios for searches for an additional Higgs state in the real Higgs singlet extension of the Standard Model in Run 2 of the LHC. The scenarios are selected such that they ful ll all relevant current theoretical and experimental constraints, but can potentially be discovered at the current LHC run. We take into account the results presented in earlier work and update the experimental constraints from relevant LHC Higgs searches and signal rate measurements. The benchmark scenarios are given separately for the low mass and high mass region, i.e. the mass range where the additional Higgsmore » state is lighter or heavier than the discovered Higgs state at around 125 GeV. They have also been presented in the framework of the LHC Higgs Cross Section Working Group.« less

Extensive Reading Coursebooks in China

ERIC Educational Resources Information Center

Renandya, Willy A.; Hu, Guangwei; Xiang, Yu

2015-01-01

This article reports on a principle-based evaluation of eight dedicated extensive reading coursebooks published in mainland China and used in many universities across the country. The aim is to determine the extent to which these coursebooks reflect a core set of nine second language acquisition and extensive reading principles. Our analysis shows…